BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Forsythia21_contig00057306
         (1205 letters)

Database: ./nr 
           69,698,275 sequences; 24,982,196,650 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

emb|CDP07797.1| unnamed protein product [Coffea canephora]            259   4e-66
ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2 [Vitis vinifera]   249   4e-63
ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform ...   248   6e-63
ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform ...   248   6e-63
ref|XP_011087923.1| PREDICTED: DNA topoisomerase 2 isoform X2 [S...   245   4e-62
ref|XP_011087914.1| PREDICTED: DNA topoisomerase 2 isoform X1 [S...   245   4e-62
ref|XP_006345427.1| PREDICTED: DNA topoisomerase 2-like [Solanum...   245   5e-62
ref|XP_012849677.1| PREDICTED: DNA topoisomerase 2 [Erythranthe ...   240   2e-60
ref|XP_007009327.1| DNA topoisomerase 2 isoform 1 [Theobroma cac...   234   1e-58
ref|XP_007009328.1| DNA topoisomerase 2 isoform 2 [Theobroma cac...   234   1e-58
ref|XP_010324649.1| PREDICTED: DNA topoisomerase 2 isoform X1 [S...   233   3e-58
dbj|BAE06274.1| topoisomerase II [Scutellaria baicalensis]            231   8e-58
ref|XP_004229644.1| PREDICTED: DNA topoisomerase 2 isoform X2 [S...   229   2e-57
ref|XP_008231457.1| PREDICTED: DNA topoisomerase 2 isoform X1 [P...   227   2e-56
ref|XP_008231458.1| PREDICTED: DNA topoisomerase 2 isoform X2 [P...   226   3e-56
ref|XP_010257162.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...   226   3e-56
ref|XP_010097430.1| DNA topoisomerase 2 [Morus notabilis] gi|587...   225   6e-56
emb|CBI24922.3| unnamed protein product [Vitis vinifera]              223   2e-55
ref|XP_010023678.1| PREDICTED: DNA topoisomerase 2-like [Eucalyp...   222   5e-55
ref|XP_002314046.2| DNA topoisomerase family protein [Populus tr...   221   8e-55

>emb|CDP07797.1| unnamed protein product [Coffea canephora]
          Length = 1486

 Score =  259 bits (661), Expect = 4e-66
 Identities = 184/400 (46%), Positives = 227/400 (56%), Gaps = 27/400 (6%)
 Frame = -1

Query: 1205 TTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNRDKLI 1026
            + E +VAGS +  EETEE+S++ATS+GVRASDYEYL+SM+IGSLT+EKVQELC +RDKL 
Sbjct: 1078 SVEAAVAGSIEDAEETEESSEVATSKGVRASDYEYLISMAIGSLTLEKVQELCADRDKLK 1137

Query: 1025 QEVEEMRKATINSLWTKDLDALERELDEQDRRDALTEEEAMEIKAKTRKASKP-----AT 861
             EV+++ KAT  SLWTKDLDALE +LDEQD  DA  E    E+++K  K   P     A 
Sbjct: 1138 GEVDDLIKATPKSLWTKDLDALESQLDEQDISDAQAEAARKEMRSKAMKDDGPKPTRQAP 1197

Query: 860  KNPRKNNKKISKTESAAEPMEISTNSEIETVSANVGPFPPSDNARVVVQKKAP-RKGKSV 684
            KNPRK NKK S TE   EPMEIS++S +ET +  V    P   A     KKAP RKGK+ 
Sbjct: 1198 KNPRKYNKKASNTEPTTEPMEISSSSALETNNV-VEVAKPKGKAG---PKKAPARKGKTF 1253

Query: 683  AALKXXXXXXXXEILALNERIAAYNL-DSSPDHAEAPESEVSEVQIKNKGPTRKAAATKK 507
            + L+        E+LAL +R+AAYNL  SSPD +E  E+E+       K    K A TKK
Sbjct: 1254 SVLRDEDDEDDDEVLALKDRLAAYNLGSSSPDQSETMETEIP------KREPSKRATTKK 1307

Query: 506  PLSTVT-----XXXXXXXXXXXXXXEVMPAEEXXXXXXXXXXXXXXXXXXXXXKRGPASK 342
            PL +VT                     + A                       KRG A+K
Sbjct: 1308 PLVSVTEISDDDDDQIEISDDEDFELEVEAAPKEKGRKKTANSKAAKPTAAPKKRGQANK 1367

Query: 341  KSQILGQKLITEVLQGA---ADSPDKKVRKIRISPFNKKSGSVLGR-----------XXX 204
             SQ++GQKLITEVL+ A     SP+KKVR++R SPFNKKSGSVL R              
Sbjct: 1368 TSQLVGQKLITEVLKPADVSKISPEKKVRRMRPSPFNKKSGSVLERLSQQETDKISPESE 1427

Query: 203  XXXXXXXXXXXXXXXESNQVVVPRARPQRANSR-KATYVL 87
                           ES QVVVPRARP+R  +R KA YV+
Sbjct: 1428 EQEESPASNASGSTEESAQVVVPRARPRRGGNRGKAKYVM 1467


>ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2 [Vitis vinifera]
          Length = 1489

 Score =  249 bits (635), Expect = 4e-63
 Identities = 170/397 (42%), Positives = 224/397 (56%), Gaps = 24/397 (6%)
 Frame = -1

Query: 1205 TTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNRDKLI 1026
            + EI+VAG+TD  EE EEN+D  +  GVRA+DYEYLLSM+IG+LT+EKVQELC +RDKL 
Sbjct: 1079 SVEIAVAGATDDTEEAEENTDAVSKGGVRATDYEYLLSMAIGTLTLEKVQELCADRDKLN 1138

Query: 1025 QEVEEMRKATINSLWTKDLDALERELDEQDRRDALTEEEAMEIKAKT-----RKASKPAT 861
            + V++++KAT  +LW  DLDALERELDEQD+ DA  EE   ++K++       K S+ A 
Sbjct: 1139 KGVDDLKKATPKALWITDLDALERELDEQDKNDARAEETRKQLKSRVMSEAGMKVSRQAP 1198

Query: 860  KNPRKNNKKISKTESAAEPMEISTNSEIETVSANVGPFPPSDNARVVVQKKAPRKGKSVA 681
            KNPRKNNKK +  E AAE M++S +S +E  S      P    A     +KAP K K + 
Sbjct: 1199 KNPRKNNKKANNAEPAAETMDVSASSAMEMESVPEVVKPKGRAA----PRKAPAKKKEMP 1254

Query: 680  ALKXXXXXXXXEILALNERIAAYNLDSSPDHAEAPESEVSEV-QIKNKGPTRKAAATKKP 504
                       E+  L ER+AAYNL+SSPD + A E+EV +V   + K P+R+AAA KKP
Sbjct: 1255 T-SVLKDEDDDEVHELKERLAAYNLESSPDGSAAMEAEVPQVPAARKKEPSRRAAAQKKP 1313

Query: 503  LSTVTXXXXXXXXXXXXXXEVMPAEE------XXXXXXXXXXXXXXXXXXXXXKRGPASK 342
            L++ T              E + A +                           KRG A+K
Sbjct: 1314 LASFTEISDDDEDDEDFEVEEVSASDVKKKGGRKPAANAKAAAAKPAAAAAKNKRGAANK 1373

Query: 341  KS-QILGQKLITEVLQGAAD---SPDKKVRKIRISPFNKKSGSVLG-------RXXXXXX 195
            +  Q+LGQ L+TE+ + A     SP+KKVRK+R SPFNKKSGSVLG              
Sbjct: 1374 QQPQLLGQTLLTEIFKPAETLGISPEKKVRKMRASPFNKKSGSVLGSTGEEDETAETEEN 1433

Query: 194  XXXXXXXXXXXXESNQVVVP-RARPQRANSRKATYVL 87
                        ESN+VV+P R RPQR N  +  YV+
Sbjct: 1434 SGSASTSNSSGGESNEVVMPARTRPQRENRVQTRYVV 1470


>ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform X2 [Nelumbo nucifera]
          Length = 1503

 Score =  248 bits (633), Expect = 6e-63
 Identities = 171/404 (42%), Positives = 224/404 (55%), Gaps = 33/404 (8%)
 Frame = -1

Query: 1199 EISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNRDKLIQE 1020
            E +VAG+ +  EE EENS++ +S+GVRASDYEYLLSM+IG+LT+EKVQELC++RDKL  E
Sbjct: 1083 EAAVAGANEDGEENEENSEVVSSRGVRASDYEYLLSMAIGTLTLEKVQELCSDRDKLNHE 1142

Query: 1019 VEEMRKATINSLWTKDLDALERELDEQDRRDALTEEEAMEIKAKT-----RKASKPATKN 855
            VEE+RKAT NSLW  DLDALE+ELDEQD+ DA  EE   E+K +       KAS+ A KN
Sbjct: 1143 VEELRKATPNSLWMNDLDALEKELDEQDKNDAQAEEARKELKNRVMSEAGMKASRQAPKN 1202

Query: 854  PRKNN-KKISKTESAAEPMEIST-NSEIETVSANVGPFPPSDNARVVVQKKAPRKGKSVA 681
            PRK N KK S +E+  E +  S+  S +ETV   V P       R    KKAP K  ++ 
Sbjct: 1203 PRKTNAKKPSTSETVTESVAASSVGSAMETVPEVVKP-----KGRGGRPKKAPAKKDNMR 1257

Query: 680  ALKXXXXXXXXEILALNERIAAYNLDSSPDHAEAPESEVSEVQIKNKGPTRKAAATKKPL 501
             +         +++ L ER+AAYNLDSSP+ +   E+EV++V  K K P+++AAA K+P 
Sbjct: 1258 LV--DSDEDDVDVIELKERLAAYNLDSSPEQSAVMETEVAKVPAKKKEPSKRAAAQKQPS 1315

Query: 500  S-----------TVTXXXXXXXXXXXXXXEVMP--AEEXXXXXXXXXXXXXXXXXXXXXK 360
            S            V               +  P   E                      K
Sbjct: 1316 SYTEISDDDDGMDVQTIREESIGEIVSDEDFEPEVEEAPKGGRGGRKPAANGKAAASTKK 1375

Query: 359  RGPASKKSQILGQKLITEVL---QGAADSPDKKVRKIRISPFNKKSGSVLGRXXXXXXXX 189
            RG A+K++ +LGQK IT++L   + A  SP+KKVRK+R SPFNKKSGSVLGR        
Sbjct: 1376 RGAANKQTSVLGQKKITDLLKPAENAGVSPEKKVRKMRASPFNKKSGSVLGRVGGMVGDI 1435

Query: 188  XXXXXXXXXXES----------NQVVVPRARPQRANSRKATYVL 87
                       +          ++VV  R RPQR N  KA YV+
Sbjct: 1436 SPMGSEEQQTGTSSASTDSAELSEVVPARPRPQRVNRGKAKYVI 1479


>ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform X1 [Nelumbo nucifera]
          Length = 1504

 Score =  248 bits (633), Expect = 6e-63
 Identities = 172/404 (42%), Positives = 223/404 (55%), Gaps = 33/404 (8%)
 Frame = -1

Query: 1199 EISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNRDKLIQE 1020
            E +VAG+ +  EE EENS++ +S+GVRASDYEYLLSM+IG+LT+EKVQELC++RDKL  E
Sbjct: 1083 EAAVAGANEDGEENEENSEVVSSRGVRASDYEYLLSMAIGTLTLEKVQELCSDRDKLNHE 1142

Query: 1019 VEEMRKATINSLWTKDLDALERELDEQDRRDALTEEEAMEIKAKT-----RKASKPATKN 855
            VEE+RKAT NSLW  DLDALE+ELDEQD+ DA  EE   E+K +       KAS+ A KN
Sbjct: 1143 VEELRKATPNSLWMNDLDALEKELDEQDKNDAQAEEARKELKNRVMSEAGMKASRQAPKN 1202

Query: 854  PRKNN-KKISKTESAAEPMEIST-NSEIETVSANVGPFPPSDNARVVVQKKAPRKGKSVA 681
            PRK N KK S +E+  E +  S+  S +ETV   V P       R    KKAP K +   
Sbjct: 1203 PRKTNAKKPSTSETVTESVAASSVGSAMETVPEVVKP-----KGRGGRPKKAPAKKQDNM 1257

Query: 680  ALKXXXXXXXXEILALNERIAAYNLDSSPDHAEAPESEVSEVQIKNKGPTRKAAATKKPL 501
             L         +++ L ER+AAYNLDSSP+ +   E+EV++V  K K P+++AAA K+P 
Sbjct: 1258 RL-VDSDEDDVDVIELKERLAAYNLDSSPEQSAVMETEVAKVPAKKKEPSKRAAAQKQPS 1316

Query: 500  S-----------TVTXXXXXXXXXXXXXXEVMP--AEEXXXXXXXXXXXXXXXXXXXXXK 360
            S            V               +  P   E                      K
Sbjct: 1317 SYTEISDDDDGMDVQTIREESIGEIVSDEDFEPEVEEAPKGGRGGRKPAANGKAAASTKK 1376

Query: 359  RGPASKKSQILGQKLITEVL---QGAADSPDKKVRKIRISPFNKKSGSVLGRXXXXXXXX 189
            RG A+K++ +LGQK IT++L   + A  SP+KKVRK+R SPFNKKSGSVLGR        
Sbjct: 1377 RGAANKQTSVLGQKKITDLLKPAENAGVSPEKKVRKMRASPFNKKSGSVLGRVGGMVGDI 1436

Query: 188  XXXXXXXXXXES----------NQVVVPRARPQRANSRKATYVL 87
                       +          ++VV  R RPQR N  KA YV+
Sbjct: 1437 SPMGSEEQQTGTSSASTDSAELSEVVPARPRPQRVNRGKAKYVI 1480


>ref|XP_011087923.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Sesamum indicum]
          Length = 1483

 Score =  245 bits (626), Expect = 4e-62
 Identities = 169/384 (44%), Positives = 217/384 (56%), Gaps = 13/384 (3%)
 Frame = -1

Query: 1199 EISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNRDKLIQE 1020
            E+++AGS D  EETEEN+         ASDY+YLLS++IG+LT EK+QEL   RDKL+QE
Sbjct: 1092 EVAIAGSLDEAEETEENTS--------ASDYDYLLSLAIGTLTAEKIQELRAERDKLMQE 1143

Query: 1019 VEEMRKATINSLWTKDLDALERE-LDEQDRRDALTEEEAMEIKAKTRKASKPATKNPRKN 843
            VE +++AT+ SLW  DLDALE + ++EQ++ +   E+E  +I   T   S+P  KNPRKN
Sbjct: 1144 VENLKRATVKSLWMNDLDALESKFIEEQNKSEKKWEKEREKING-TVNISRPVQKNPRKN 1202

Query: 842  NKKISKTESAAEPMEISTNSEIETVSANVGPFPPSDNARVVVQKKAP-RKGKSVAALKXX 666
            NKK +  ES    ME+S ++  E  + N G        R   +KKAP  K  SVA     
Sbjct: 1203 NKKATNKES---QMEVSGDTVPE--AGNAGDI-KKPKGRTAAKKKAPAEKVTSVA----- 1251

Query: 665  XXXXXXEILALNERIAAYNLDSSPDHAEAPES-EVSEVQIKNKGPTRKAAATKKPLSTVT 489
                  EI  L  R+AAYN DSSPD  +  E+ EVS++Q K K P+RKAAA KKPL TV+
Sbjct: 1252 DENDDEEISDLRHRLAAYNFDSSPDRPQEMETEEVSQLQTKKKEPSRKAAAQKKPLPTVS 1311

Query: 488  XXXXXXXXXXXXXXEVMPAEEXXXXXXXXXXXXXXXXXXXXXKRGP-ASKKSQILGQKLI 312
                          +    +E                     KRGP ASK+SQ LGQKLI
Sbjct: 1312 ESHDDDDIQIIDDDDDFVPDEKKKKGGRKPGNAKAAKPPSTKKRGPAASKQSQTLGQKLI 1371

Query: 311  TEVLQGAADSPDKKVRKIRISPFNKKSGSVLGRXXXXXXXXXXXXXXXXXXESN------ 150
            TEVL+ A +SP+KKVRK+R SPFNKKSGS+LGR                   ++      
Sbjct: 1372 TEVLKPAENSPEKKVRKVRASPFNKKSGSILGRTINVEEEEEGSTSAEQADSTSTLGSVT 1431

Query: 149  ---QVVVPRARPQRANSRKATYVL 87
               Q V P+ARPQRAN  KATYV+
Sbjct: 1432 DVGQAVAPKARPQRANRGKATYVI 1455


>ref|XP_011087914.1| PREDICTED: DNA topoisomerase 2 isoform X1 [Sesamum indicum]
          Length = 1484

 Score =  245 bits (626), Expect = 4e-62
 Identities = 167/383 (43%), Positives = 218/383 (56%), Gaps = 12/383 (3%)
 Frame = -1

Query: 1199 EISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNRDKLIQE 1020
            E+++AGS D  EETEEN+         ASDY+YLLS++IG+LT EK+QEL   RDKL+QE
Sbjct: 1092 EVAIAGSLDEAEETEENTS--------ASDYDYLLSLAIGTLTAEKIQELRAERDKLMQE 1143

Query: 1019 VEEMRKATINSLWTKDLDALERE-LDEQDRRDALTEEEAMEIKAKTRKASKPATKNPRKN 843
            VE +++AT+ SLW  DLDALE + ++EQ++ +   E+E  +I   T   S+P  KNPRKN
Sbjct: 1144 VENLKRATVKSLWMNDLDALESKFIEEQNKSEKKWEKEREKING-TVNISRPVQKNPRKN 1202

Query: 842  NKKISKTESAAEPMEISTNSEIETVSANVGPFPPSDNARVVVQKKAPRKGKSVAALKXXX 663
            NKK +  ES    ME+S ++  E  + N G        R   +KKAP + K V ++    
Sbjct: 1203 NKKATNKES---QMEVSGDTVPE--AGNAGDI-KKPKGRTAAKKKAPAE-KQVTSV--AD 1253

Query: 662  XXXXXEILALNERIAAYNLDSSPDHAEAPES-EVSEVQIKNKGPTRKAAATKKPLSTVTX 486
                 EI  L  R+AAYN DSSPD  +  E+ EVS++Q K K P+RKAAA KKPL TV+ 
Sbjct: 1254 ENDDEEISDLRHRLAAYNFDSSPDRPQEMETEEVSQLQTKKKEPSRKAAAQKKPLPTVSE 1313

Query: 485  XXXXXXXXXXXXXEVMPAEEXXXXXXXXXXXXXXXXXXXXXKRGP-ASKKSQILGQKLIT 309
                         +    +E                     KRGP ASK+SQ LGQKLIT
Sbjct: 1314 SHDDDDIQIIDDDDDFVPDEKKKKGGRKPGNAKAAKPPSTKKRGPAASKQSQTLGQKLIT 1373

Query: 308  EVLQGAADSPDKKVRKIRISPFNKKSGSVLGRXXXXXXXXXXXXXXXXXXESN------- 150
            EVL+ A +SP+KKVRK+R SPFNKKSGS+LGR                   ++       
Sbjct: 1374 EVLKPAENSPEKKVRKVRASPFNKKSGSILGRTINVEEEEEGSTSAEQADSTSTLGSVTD 1433

Query: 149  --QVVVPRARPQRANSRKATYVL 87
              Q V P+ARPQRAN  KATYV+
Sbjct: 1434 VGQAVAPKARPQRANRGKATYVI 1456


>ref|XP_006345427.1| PREDICTED: DNA topoisomerase 2-like [Solanum tuberosum]
          Length = 1485

 Score =  245 bits (625), Expect = 5e-62
 Identities = 165/388 (42%), Positives = 211/388 (54%), Gaps = 17/388 (4%)
 Frame = -1

Query: 1199 EISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNRDKLIQE 1020
            E  VA STD  E++EE+ +  +++GVRASDY+YLLSM+IG+LT+EKVQELC +RDKL  E
Sbjct: 1076 EAVVADSTDDAEDSEESPE-ESNKGVRASDYDYLLSMAIGTLTLEKVQELCADRDKLNAE 1134

Query: 1019 VEEMRKATINSLWTKDLDALERELDEQDRRDALTEEEAMEIKAKTRKASKPATK-NPRKN 843
            VE+MR AT   LW KDLD L+++LDEQD+ D  TEE   ++K K   A+  A K  PRK 
Sbjct: 1135 VEDMRNATPKDLWMKDLDVLDKQLDEQDKLDIQTEEAREKLKKKVMNAAGKAPKPKPRKT 1194

Query: 842  NKKISKTESAAEPMEISTNSEIETVSANVGPFPPSDNARVVVQKKAPRKGKSVAALKXXX 663
             KK +  ES AEPM++S  S  ET +      P     R    KKAP K K V       
Sbjct: 1195 TKKAAVVESTAEPMDVSVGSMAETANVTEVAKP---KGRGGGSKKAPAKAKPVVV---ED 1248

Query: 662  XXXXXEILALNERIAAYNLDSSPDHAEAPESEVSEVQIKNKGPTRKAAATKKPLSTVTXX 483
                 E+LAL +R+AAYNL+SSPD +E  E+E  + Q   K P ++AAA KK L +    
Sbjct: 1249 EEEEDEVLALKDRLAAYNLNSSPDRSEVTETEAPKAQ--TKAPAKRAAAQKKALPSTPDV 1306

Query: 482  XXXXXXXXXXXXEVMPAE----EXXXXXXXXXXXXXXXXXXXXXKRGPASKKSQILGQKL 315
                             E                          KR PA+K+SQ +GQ+L
Sbjct: 1307 SEGEDEIEISDDNEFAPEVAVGGKKKGGRKPAAAKAAAAPKPPKKRAPANKQSQSVGQRL 1366

Query: 314  ITEVLQGAAD---SPDKKVRKIRISPFNKKSGSVLGR---------XXXXXXXXXXXXXX 171
            IT+VL+ A D   SPD+KVRK+R SPFNKKSG+V+GR                       
Sbjct: 1367 ITQVLKPAEDAGVSPDRKVRKMRESPFNKKSGAVMGRNTSSSSSTSHESEVSPPIPSLGS 1426

Query: 170  XXXXESNQVVVPRARPQRANSRKATYVL 87
                 S  VV P+ARPQRAN  K TYV+
Sbjct: 1427 LEEEVSEVVVAPKARPQRANRTKTTYVI 1454


>ref|XP_012849677.1| PREDICTED: DNA topoisomerase 2 [Erythranthe guttatus]
            gi|604314150|gb|EYU27037.1| hypothetical protein
            MIMGU_mgv1a000169mg [Erythranthe guttata]
          Length = 1503

 Score =  240 bits (612), Expect = 2e-60
 Identities = 156/390 (40%), Positives = 219/390 (56%), Gaps = 17/390 (4%)
 Frame = -1

Query: 1205 TTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNRDKLI 1026
            T E++VAG+TD  EETE+N+++  ++GV ASDY+YLLS++IG+LT EK+QEL + R++L 
Sbjct: 1092 TPEVAVAGATDDTEETEDNTEVEIAKGVSASDYDYLLSLAIGTLTAEKLQELRDERERLT 1151

Query: 1025 QEVEEMRKATINSLWTKDLDALERE-LDEQDRRDALTEEEAMEIKAKTRKASKPATKNPR 849
            QEVE+++K+T+ SLWTKDLDALE + +++    +   EE+   I+    K ++P  KNPR
Sbjct: 1152 QEVEDLKKSTVKSLWTKDLDALEAKIIEDLKNSEKKWEEDRQRIQGGETKIARPLAKNPR 1211

Query: 848  KNNKK-ISKTESAAEPMEISTNSEIETVSANVGPFPPSDNARVVVQKKAPRKGKSVAALK 672
            KN KK  +K ES AE M++S N+  ET    V             +KKAP   K VA   
Sbjct: 1212 KNTKKATTKKESTAEHMDVSDNTVTET--DKVAEIKKPRGKAAAAKKKAP-VAKVVA--- 1265

Query: 671  XXXXXXXXEILALNERIAAYNLDSSPDHAEAPESEVSEVQIKNKGPTRKAAATKKPLSTV 492
                     +  L +RIAAYN DSSPD AE  E+E+ ++Q K K PT++AA  KK +S V
Sbjct: 1266 EADEDDDDGVAELRQRIAAYNFDSSPDRAEDMETELPQLQTKKKEPTKRAAPRKKQVSIV 1325

Query: 491  TXXXXXXXXXXXXXXEVMPAE--EXXXXXXXXXXXXXXXXXXXXXKRGPASKKSQILGQK 318
            +              +  P +  +                     KRGPASK+SQ++GQK
Sbjct: 1326 SDDEEDDDIEIIDDDDFEPEDKKKKGGRKPANPKAAAAKPPAGAKKRGPASKQSQLVGQK 1385

Query: 317  LITEVLQ---GAADSPDKKVRKIRISPFNKKSGSVLGRXXXXXXXXXXXXXXXXXXESNQ 147
            LITEVL+    A DSP+KKVR++R SPFNKKS S+LGR                  E  +
Sbjct: 1386 LITEVLKPTAAADDSPEKKVRRMRASPFNKKSSSILGRGAINVDDDEDKEIGETSNEQER 1445

Query: 146  VVVPR----------ARPQRANSRKATYVL 87
              V            +RP+R N R+ +YV+
Sbjct: 1446 SSVSDDVSKGVGPAVSRPKRVNRRQTSYVI 1475


>ref|XP_007009327.1| DNA topoisomerase 2 isoform 1 [Theobroma cacao]
            gi|508726240|gb|EOY18137.1| DNA topoisomerase 2 isoform 1
            [Theobroma cacao]
          Length = 1473

 Score =  234 bits (597), Expect = 1e-58
 Identities = 162/396 (40%), Positives = 219/396 (55%), Gaps = 23/396 (5%)
 Frame = -1

Query: 1205 TTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNRDKLI 1026
            T E++VAG+TD  EETEENS+++ ++G++ASDY+YLLSM+IGSLT+EKVQELC +RDKL 
Sbjct: 1071 TVEVAVAGATDDTEETEENSEVS-AKGLQASDYDYLLSMAIGSLTLEKVQELCADRDKLQ 1129

Query: 1025 QEVEEMRKATINSLWTKDLDALERELDEQDRRDALTEEEAMEIKAK---TRKASKPATKN 855
            QEVE++RKAT  SLW KDLD LE +LDEQD+  A  EE A  +K +    ++A + A K 
Sbjct: 1130 QEVEDLRKATPKSLWLKDLDNLEIQLDEQDKA-AQAEEAAKLVKGRGEAGKRAQRQAPKI 1188

Query: 854  PRKNNKKISKTESAAEPMEISTNSEIETVSANVGPFPPSDNARVVVQKKAPRKGKSVAAL 675
            PRK NKK    E+  E  +IS++S +ET +A     P          +   RK K   + 
Sbjct: 1189 PRKINKKEKNAETVTETTDISSSSAMETETAPAAVKPKG--------RGGSRKAKKDDS- 1239

Query: 674  KXXXXXXXXEILALNERIAAYNLDSSPDHAEAPESEVSEVQIKNKGPTRKAAAT-KKPLS 498
                      I  L ER+A YNLDSSPDH+ A E+EV +V    K P+++AAA  KKP +
Sbjct: 1240 -DDDDDEDFGIPDLRERLAKYNLDSSPDHSAAMETEVPQVPAGKKEPSKRAAAARKKPAT 1298

Query: 497  TVTXXXXXXXXXXXXXXEV---------MPAEEXXXXXXXXXXXXXXXXXXXXXKRGPAS 345
            +++              ++          PA +                     KRGPA+
Sbjct: 1299 SLSEISESIGEIDINDEDLEVVEVAAAAAPAGKKGGRKPAANSKAAAKPPAAAKKRGPAA 1358

Query: 344  KKSQILGQKLITEVLQGAAD---SPDKKVRKIRISPFNKKSGSVLGRXXXXXXXXXXXXX 174
               +   QKL+TE+L+ A D   SP+KKVRK+R SPFNKKSGSVLGR             
Sbjct: 1359 AGKKSQQQKLLTEMLKPAEDSGISPEKKVRKMRASPFNKKSGSVLGRVGKELESTTDSEE 1418

Query: 173  XXXXXESN-------QVVVPRARPQRANSRKATYVL 87
                   +       ++V  R RPQR N ++ TYVL
Sbjct: 1419 TFGSSSMSADTEEVTEIVPARPRPQRTNRKQTTYVL 1454


>ref|XP_007009328.1| DNA topoisomerase 2 isoform 2 [Theobroma cacao]
            gi|508726241|gb|EOY18138.1| DNA topoisomerase 2 isoform 2
            [Theobroma cacao]
          Length = 1285

 Score =  234 bits (596), Expect = 1e-58
 Identities = 164/399 (41%), Positives = 222/399 (55%), Gaps = 26/399 (6%)
 Frame = -1

Query: 1205 TTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNRDKLI 1026
            T E++VAG+TD  EETEENS+++ ++G++ASDY+YLLSM+IGSLT+EKVQELC +RDKL 
Sbjct: 882  TVEVAVAGATDDTEETEENSEVS-AKGLQASDYDYLLSMAIGSLTLEKVQELCADRDKLQ 940

Query: 1025 QEVEEMRKATINSLWTKDLDALERELDEQDRRDALTEEEAMEIKAK---TRKASKPATKN 855
            QEVE++RKAT  SLW KDLD LE +LDEQD+  A  EE A  +K +    ++A + A K 
Sbjct: 941  QEVEDLRKATPKSLWLKDLDNLEIQLDEQDKA-AQAEEAAKLVKGRGEAGKRAQRQAPKI 999

Query: 854  PRKNNKKISKTESAAEPMEISTNSEIETVSANVGPFPPSDNARVVVQKKAPRKGKSVAAL 675
            PRK NKK    E+  E  +IS++S +ET          ++ A   V+ K   +G S  A 
Sbjct: 1000 PRKINKKEKNAETVTETTDISSSSAMET----------AETAPAAVKPKG--RGGSRKAK 1047

Query: 674  K---XXXXXXXXEILALNERIAAYNLDSSPDHAEAPESEVSEVQIKNKGPTRKAAAT-KK 507
            K            I  L ER+A YNLDSSPDH+ A E+EV +V    K P+++AAA  KK
Sbjct: 1048 KDDSDDDDDEDFGIPDLRERLAKYNLDSSPDHSAAMETEVPQVPAGKKEPSKRAAAARKK 1107

Query: 506  PLSTVTXXXXXXXXXXXXXXEV---------MPAEEXXXXXXXXXXXXXXXXXXXXXKRG 354
            P ++++              ++          PA +                     KRG
Sbjct: 1108 PATSLSEISESIGEIDINDEDLEVVEVAAAAAPAGKKGGRKPAANSKAAAKPPAAAKKRG 1167

Query: 353  PASKKSQILGQKLITEVLQGAAD---SPDKKVRKIRISPFNKKSGSVLGRXXXXXXXXXX 183
            PA+   +   QKL+TE+L+ A D   SP+KKVRK+R SPFNKKSGSVLGR          
Sbjct: 1168 PAAAGKKSQQQKLLTEMLKPAEDSGISPEKKVRKMRASPFNKKSGSVLGRVGKELESTTD 1227

Query: 182  XXXXXXXXESN-------QVVVPRARPQRANSRKATYVL 87
                      +       ++V  R RPQR N ++ TYVL
Sbjct: 1228 SEETFGSSSMSADTEEVTEIVPARPRPQRTNRKQTTYVL 1266


>ref|XP_010324649.1| PREDICTED: DNA topoisomerase 2 isoform X1 [Solanum lycopersicum]
          Length = 1478

 Score =  233 bits (593), Expect = 3e-58
 Identities = 163/389 (41%), Positives = 211/389 (54%), Gaps = 18/389 (4%)
 Frame = -1

Query: 1199 EISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNRDKLIQE 1020
            E  VA STD  +++EE+ +  +S+GVRASDY+YLLSM+IG+LT+EKVQELC +RDKL  E
Sbjct: 1076 EAVVADSTDDADDSEESPE-ESSRGVRASDYDYLLSMAIGTLTLEKVQELCADRDKLNAE 1134

Query: 1019 VEEMRKATINSLWTKDLDALERELDEQDRRDALTEEEAMEIKAKTRKAS-KPATK-NPRK 846
            VE+MR AT   LW KDLD L+++LDEQD+ D  TEE   ++K K   A+ K A K  PRK
Sbjct: 1135 VEDMRNATPKHLWMKDLDVLDKQLDEQDKIDIQTEEAREKLKKKVMNAAGKAAPKPKPRK 1194

Query: 845  NNKKISKTESAAEPMEISTNSEIETVSANVGPFPPSDNARVVVQKKAPRKGKSVAALKXX 666
             NK   K ES AE M++S  S  ET  ANV        + VV  K   R  K    +   
Sbjct: 1195 TNK---KAESTAESMDVSFGSTAET--ANV--------SEVVKPKGRGRPAKQAKPIVVE 1241

Query: 665  XXXXXXEILALNERIAAYNLDSSPDHAEAPESEVSEVQIKNKGPTRKAAATKKPLSTVTX 486
                  E+LAL +R+AAYNL+SSPD +E  E+EV + Q   K P ++AAA KK L +   
Sbjct: 1242 DEEEEDEVLALKDRLAAYNLNSSPDRSEVTETEVPKAQ--TKAPAKRAAAQKKALPSTPD 1299

Query: 485  XXXXXXXXXXXXXEVMPAEEXXXXXXXXXXXXXXXXXXXXXKRG---PASKKSQILGQKL 315
                         E  PA                         G   PA+ +SQ +GQ+L
Sbjct: 1300 VSDGEDAIEIDDDEFEPAAAVGGKKKGGRKPAAAKAAAAPKPPGKKAPANNQSQSVGQRL 1359

Query: 314  ITEVLQGAAD---SPDKKVRKIRISPFNKKSGSVLGR----------XXXXXXXXXXXXX 174
            IT+VL+ A D   SPD+KVRK+R SPFNKKSG+V+G+                       
Sbjct: 1360 ITQVLKPAEDAGVSPDRKVRKMRASPFNKKSGAVMGKNTSSSSTSSHESEEVSPLIPSLG 1419

Query: 173  XXXXXESNQVVVPRARPQRANSRKATYVL 87
                  S  VV P+ARPQRA  +  TYV+
Sbjct: 1420 SLDEEVSEVVVAPKARPQRATKKTTTYVI 1448


>dbj|BAE06274.1| topoisomerase II [Scutellaria baicalensis]
          Length = 1469

 Score =  231 bits (589), Expect = 8e-58
 Identities = 161/374 (43%), Positives = 208/374 (55%), Gaps = 3/374 (0%)
 Frame = -1

Query: 1199 EISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNRDKLIQE 1020
            E+++AG+TD  EETEENS++  + GV +SDY+YLLS++IG+LT EK+QEL   RDKL+QE
Sbjct: 1089 EVAIAGATDDGEETEENSEVPIAPGVSSSDYDYLLSLAIGTLTTEKMQELRAERDKLMQE 1148

Query: 1019 VEEMRKATINSLWTKDLDALEREL-DEQDRRDALTEEEAMEIKAKTRKASKPATKNPRKN 843
            VEE++++T  SLW KDLDALE +L +EQ   +   E+   +I  KT    +   KNPRK 
Sbjct: 1149 VEELKQSTARSLWNKDLDALEDKLAEEQKIYEETWEKNKRKIHGKT-DTLEIIQKNPRK- 1206

Query: 842  NKKISKTESAAEPMEISTNSEIETVSANVGPFPPSDNARVVVQKKAPRKGKSVAALKXXX 663
            NKK +K ESA E MEIS N+  ET      P       +   +KK P   K V A     
Sbjct: 1207 NKKTTKKESAVE-MEISENTTTETDVKIKKP-----RGKAAAKKKEP-AAKVVTAAPVEE 1259

Query: 662  XXXXXEILALNERIAAYNLDSSPDHAEAPESEVSEVQIKNKGPTRKAAATKKPLSTVTXX 483
                  I  L +RIAAYN DSSPDH+E   +EV+ VQ KNK P R+ AA KK LS  +  
Sbjct: 1260 QEDDDGIADLRQRIAAYNFDSSPDHSEDMATEVAPVQTKNKQPARRGAAQKKTLSAASET 1319

Query: 482  XXXXXXXXXXXXEVMPAEEXXXXXXXXXXXXXXXXXXXXXKRGPASKK-SQILGQKLITE 306
                             E                      KRGP++K+ SQ++GQKLITE
Sbjct: 1320 DEDDDAF----------EPEEKKKKGGRKPAAAKAPAAAKKRGPSAKQSSQLVGQKLITE 1369

Query: 305  VLQGAA-DSPDKKVRKIRISPFNKKSGSVLGRXXXXXXXXXXXXXXXXXXESNQVVVPRA 129
            VL+ AA DSP+KKVR++R SPFNKKS S+LG+                           A
Sbjct: 1370 VLKPAADDSPEKKVRRMRESPFNKKSSSILGKTINIDDDDEEETSGTSSMNEGAAA---A 1426

Query: 128  RPQRANSRKATYVL 87
            RP+RAN  KA YV+
Sbjct: 1427 RPKRANRGKAKYVI 1440


>ref|XP_004229644.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Solanum lycopersicum]
          Length = 1477

 Score =  229 bits (585), Expect = 2e-57
 Identities = 159/389 (40%), Positives = 208/389 (53%), Gaps = 18/389 (4%)
 Frame = -1

Query: 1199 EISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNRDKLIQE 1020
            E  VA STD  +++EE+ +  +S+GVRASDY+YLLSM+IG+LT+EKVQELC +RDKL  E
Sbjct: 1076 EAVVADSTDDADDSEESPE-ESSRGVRASDYDYLLSMAIGTLTLEKVQELCADRDKLNAE 1134

Query: 1019 VEEMRKATINSLWTKDLDALERELDEQDRRDALTEEEAMEIKAKTRKAS-KPATK-NPRK 846
            VE+MR AT   LW KDLD L+++LDEQD+ D  TEE   ++K K   A+ K A K  PRK
Sbjct: 1135 VEDMRNATPKHLWMKDLDVLDKQLDEQDKIDIQTEEAREKLKKKVMNAAGKAAPKPKPRK 1194

Query: 845  NNKKISKTESAAEPMEISTNSEIETVSANVGPFPPSDNARVVVQKKAPRKGKSVAALKXX 666
             NK   K ES AE M++S  S  ET            N   VV+ K   +      +   
Sbjct: 1195 TNK---KAESTAESMDVSFGSTAETA-----------NVSEVVKPKGRGRPAKAKPIVVE 1240

Query: 665  XXXXXXEILALNERIAAYNLDSSPDHAEAPESEVSEVQIKNKGPTRKAAATKKPLSTVTX 486
                  E+LAL +R+AAYNL+SSPD +E  E+EV + Q   K P ++AAA KK L +   
Sbjct: 1241 DEEEEDEVLALKDRLAAYNLNSSPDRSEVTETEVPKAQ--TKAPAKRAAAQKKALPSTPD 1298

Query: 485  XXXXXXXXXXXXXEVMPAEEXXXXXXXXXXXXXXXXXXXXXKRG---PASKKSQILGQKL 315
                         E  PA                         G   PA+ +SQ +GQ+L
Sbjct: 1299 VSDGEDAIEIDDDEFEPAAAVGGKKKGGRKPAAAKAAAAPKPPGKKAPANNQSQSVGQRL 1358

Query: 314  ITEVLQGAAD---SPDKKVRKIRISPFNKKSGSVLGR----------XXXXXXXXXXXXX 174
            IT+VL+ A D   SPD+KVRK+R SPFNKKSG+V+G+                       
Sbjct: 1359 ITQVLKPAEDAGVSPDRKVRKMRASPFNKKSGAVMGKNTSSSSTSSHESEEVSPLIPSLG 1418

Query: 173  XXXXXESNQVVVPRARPQRANSRKATYVL 87
                  S  VV P+ARPQRA  +  TYV+
Sbjct: 1419 SLDEEVSEVVVAPKARPQRATKKTTTYVI 1447


>ref|XP_008231457.1| PREDICTED: DNA topoisomerase 2 isoform X1 [Prunus mume]
          Length = 1471

 Score =  227 bits (578), Expect = 2e-56
 Identities = 157/386 (40%), Positives = 203/386 (52%), Gaps = 15/386 (3%)
 Frame = -1

Query: 1199 EISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNRDKLIQE 1020
            E  VAG+ +  EETEENS+ A+  G R SDYEYL+SM+IG+LTIE+VQ LC +RDK+  E
Sbjct: 1082 EPEVAGAIEDTEETEENSESASGNGARISDYEYLISMAIGTLTIERVQALCADRDKVNNE 1141

Query: 1019 VEEMRKATINSLWTKDLDALERELDEQDRRDALTEEEAMEIK-----AKTRKASKPATKN 855
            V E+R +T  SLW KDLDALE EL E ++ +AL EE   + +     A   K SKPA KN
Sbjct: 1142 VAELRNSTPRSLWLKDLDALEMELGELEKSEALAEEAKKKSRNQVKNAPAAKVSKPAPKN 1201

Query: 854  PRKNNKKISKTESAAEPMEISTNSEIETVSANVGPFPPSDNARV-VVQKKAPRKGKSVAA 678
            PRKNNKK +  E+AAE  E S++   E   A     P     +V  V KKAP   K  A 
Sbjct: 1202 PRKNNKKANNAEAAAESRETSSSFVFEMEKA-----PEIVKRKVGAVAKKAPAGKKQQAK 1256

Query: 677  LKXXXXXXXXEILALNERIAAYNLDSSPDHAEAPESEVSEVQIKNKGPTRKAAATKKPLS 498
                      E+L L +R+AAYNLDSSP+++   E+EV +  ++ K P+++A        
Sbjct: 1257 SAVVLSDDDDEVLELKDRLAAYNLDSSPENSAGKETEVPQEPVQRKEPSKRA-------- 1308

Query: 497  TVTXXXXXXXXXXXXXXEVMPAEEXXXXXXXXXXXXXXXXXXXXXKRGPASKKSQI---L 327
                                PA                       KRG A+K+SQ     
Sbjct: 1309 ----MQIDDDEDFEVEIAAAPAAGKKGGRKAAGTTKASKPPAAAKKRGAANKQSQASSSS 1364

Query: 326  GQKLITEVLQGAAD---SPDKKVRKIRISPFNKKSGSVLGR---XXXXXXXXXXXXXXXX 165
            GQKL+T++L+ A     SP+ KVRK+R SPFNKKSGSV+GR                   
Sbjct: 1365 GQKLLTDMLKPAETSGISPEPKVRKMRASPFNKKSGSVMGRESLEVEMAESEEKVDTPST 1424

Query: 164  XXESNQVVVPRARPQRANSRKATYVL 87
               S+  V  RARPQRAN R+  YVL
Sbjct: 1425 EERSDAPVAARARPQRANRRQTRYVL 1450


>ref|XP_008231458.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Prunus mume]
          Length = 1470

 Score =  226 bits (576), Expect = 3e-56
 Identities = 158/386 (40%), Positives = 204/386 (52%), Gaps = 15/386 (3%)
 Frame = -1

Query: 1199 EISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNRDKLIQE 1020
            E  VAG+ +  EETEENS+ A+  G R SDYEYL+SM+IG+LTIE+VQ LC +RDK+  E
Sbjct: 1082 EPEVAGAIEDTEETEENSESASGNGARISDYEYLISMAIGTLTIERVQALCADRDKVNNE 1141

Query: 1019 VEEMRKATINSLWTKDLDALERELDEQDRRDALTEEEAMEIK-----AKTRKASKPATKN 855
            V E+R +T  SLW KDLDALE EL E ++ +AL EE   + +     A   K SKPA KN
Sbjct: 1142 VAELRNSTPRSLWLKDLDALEMELGELEKSEALAEEAKKKSRNQVKNAPAAKVSKPAPKN 1201

Query: 854  PRKNNKKISKTESAAEPMEISTNSEIETVSANVGPFPPSDNARV-VVQKKAPRKGKSVAA 678
            PRKNNKK +  E+AAE  E S++   E   A     P     +V  V KKAP  GK  A 
Sbjct: 1202 PRKNNKKANNAEAAAESRETSSSFVFEMEKA-----PEIVKRKVGAVAKKAP-AGKKQAK 1255

Query: 677  LKXXXXXXXXEILALNERIAAYNLDSSPDHAEAPESEVSEVQIKNKGPTRKAAATKKPLS 498
                      E+L L +R+AAYNLDSSP+++   E+EV +  ++ K P+++A        
Sbjct: 1256 SAVVLSDDDDEVLELKDRLAAYNLDSSPENSAGKETEVPQEPVQRKEPSKRA-------- 1307

Query: 497  TVTXXXXXXXXXXXXXXEVMPAEEXXXXXXXXXXXXXXXXXXXXXKRGPASKKSQI---L 327
                                PA                       KRG A+K+SQ     
Sbjct: 1308 ----MQIDDDEDFEVEIAAAPAAGKKGGRKAAGTTKASKPPAAAKKRGAANKQSQASSSS 1363

Query: 326  GQKLITEVLQGAAD---SPDKKVRKIRISPFNKKSGSVLGR---XXXXXXXXXXXXXXXX 165
            GQKL+T++L+ A     SP+ KVRK+R SPFNKKSGSV+GR                   
Sbjct: 1364 GQKLLTDMLKPAETSGISPEPKVRKMRASPFNKKSGSVMGRESLEVEMAESEEKVDTPST 1423

Query: 164  XXESNQVVVPRARPQRANSRKATYVL 87
               S+  V  RARPQRAN R+  YVL
Sbjct: 1424 EERSDAPVAARARPQRANRRQTRYVL 1449


>ref|XP_010257162.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 2-like [Nelumbo
            nucifera]
          Length = 1489

 Score =  226 bits (575), Expect = 3e-56
 Identities = 164/411 (39%), Positives = 215/411 (52%), Gaps = 38/411 (9%)
 Frame = -1

Query: 1205 TTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNRDKLI 1026
            T E++VAG+T+  EE EENS++ +S+GVRASDYEYLLSM+IG+LT+EKVQELC + +KL 
Sbjct: 1065 TVEVAVAGATEDAEENEENSEVVSSKGVRASDYEYLLSMAIGTLTLEKVQELCADSNKLN 1124

Query: 1025 QEVEEMRKATINSLWTKDLDALERELDEQDRRDALTEEEAMEIKAKTR-----KASKPAT 861
             EV+E+RKAT  +LW +DLDALE+ELDEQD+ DA  E+   E+K++       K S+ A 
Sbjct: 1125 HEVDELRKATPKTLWLRDLDALEKELDEQDKNDAQAEDARKELKSRVMSDAGLKVSRQAP 1184

Query: 860  KNPRKNN-KKISKTESAAEPMEISTNSEIETVSANVGPFPPSDNARVVVQKKAPRKGKSV 684
            KNPRK N KK +  E  AE +  S  S +ET +      P      +    KA  K +  
Sbjct: 1185 KNPRKTNAKKNNNLEPVAESVAASVGSAMETGNVAEVAKPKGRGGPM----KASAKKQDQ 1240

Query: 683  AALKXXXXXXXXEILALNERIAAYNLDSSPDHAEAPESEVSE-VQIKNKGPTRKAAATKK 507
             AL         ++L L ER+AAYNLDSSPD + A E+EV++    + KGP++ AAA KK
Sbjct: 1241 LAL-ADSDEDDEDVLELKERLAAYNLDSSPDQSAAMETEVAKPPAARKKGPSKMAAAQKK 1299

Query: 506  PLSTVTXXXXXXXXXXXXXXEVM----------PAEEXXXXXXXXXXXXXXXXXXXXXKR 357
              S+ T              E M          P                         +
Sbjct: 1300 HPSSYTENSDDDDVTMHTIEENMRENGNDEDFEPEAAGPRGGKKGGRKPAAAKVKTAAAK 1359

Query: 356  GPASKKSQ--------ILGQKLITEVLQ---GAADSPDKKVRKIRISPFNKKSGSVLGRX 210
              A+ K +        +L QKLITEVL+    +  SP+KKVRK+R  PFN+KS SVLGR 
Sbjct: 1360 PTAATKKRGPANKQPSLLSQKLITEVLKPVDNSGVSPEKKVRKMRAFPFNRKSASVLGRV 1419

Query: 209  XXXXXXXXXXXXXXXXXESN----------QVVVPRARPQRANSRKATYVL 87
                              S+            VV R RPQRAN  KA YVL
Sbjct: 1420 SGKVGEVSPKLSEEEPGSSSGSASTNTEEVSEVVARPRPQRANRGKARYVL 1470


>ref|XP_010097430.1| DNA topoisomerase 2 [Morus notabilis] gi|587879182|gb|EXB68160.1| DNA
            topoisomerase 2 [Morus notabilis]
          Length = 1451

 Score =  225 bits (573), Expect = 6e-56
 Identities = 161/408 (39%), Positives = 207/408 (50%), Gaps = 37/408 (9%)
 Frame = -1

Query: 1199 EISVAGSTDVPEETEENSDM-ATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNRDKLIQ 1023
            E  VAG T+  E+TEENS+  A S   R SDYEYLLSM+IG+LT+EKVQ LC  +DKL  
Sbjct: 1042 EPEVAGVTEDAEDTEENSNAEAISTEARISDYEYLLSMAIGTLTLEKVQALCGEKDKLNN 1101

Query: 1022 EVEEMRKATINSLWTKDLDALERELDEQDRRDALTEEEAMEIKAKTR-----KASKPATK 858
            EVEE+RKAT  SLW KDLDALE +LDE ++ DA  EE   + K + +     K S+ A K
Sbjct: 1102 EVEELRKATPKSLWVKDLDALETQLDELNKSDAQAEEARKKSKGQVKNAAVSKVSRQAPK 1161

Query: 857  NPRKNNKKISKTESAAE-------PMEISTNSEIETVSANVGPFPPSDNARVVVQKKAPR 699
             PRKN KK S  E+ A+        ME     E+       GP            KKA  
Sbjct: 1162 VPRKNTKKASNAEAIADITENFDSAMEFEKAPEVAKPKGRAGP------------KKAAS 1209

Query: 698  KGKSVAALKXXXXXXXXEILALNERIAAYNLDSSPDHAEAPESEVSEVQIKNKGPTRKAA 519
            K      +         E+LAL +R+AAYNLDSSPD +   ++E  +V +  K PT++AA
Sbjct: 1210 K-----VVVEDDDDDDDEVLALKDRLAAYNLDSSPDKSSEMDTEAPQVPVPKKAPTKRAA 1264

Query: 518  ATKKPLSTVT--------XXXXXXXXXXXXXXEVMPAEE-----XXXXXXXXXXXXXXXX 378
            A KK L+TV+                         PA+                      
Sbjct: 1265 AQKKTLATVSETVNLDDDDDDEIDGDEDFELESTAPAKAAAKKGGKKPAVSTKAVSKAPA 1324

Query: 377  XXXXXKRGPASKKSQILGQKLITEVLQGAAD---SPDKKVRKIRISPFNKKSGSVLGRXX 207
                 +RG A+K+ Q+LGQKL+T++L+ A +   SP+KKVRK+R SPFNKKSGSVLGR  
Sbjct: 1325 AAATKRRGAANKEPQVLGQKLLTDMLKPAENSGLSPEKKVRKMRASPFNKKSGSVLGRAV 1384

Query: 206  XXXXXXXXXXXXXXXXESN--------QVVVPRARPQRANSRKATYVL 87
                             S         +V   +ARPQRAN  +A YVL
Sbjct: 1385 NIDDDDEATTASQENSPSTSESVDDVVEVPASKARPQRANRTQARYVL 1432


>emb|CBI24922.3| unnamed protein product [Vitis vinifera]
          Length = 1452

 Score =  223 bits (568), Expect = 2e-55
 Identities = 157/372 (42%), Positives = 206/372 (55%), Gaps = 24/372 (6%)
 Frame = -1

Query: 1130 QGVRASDYEYLLSMSIGSLTIEKVQELCNNRDKLIQEVEEMRKATINSLWTKDLDALERE 951
            Q VRA+DYEYLLSM+IG+LT+EKVQELC +RDKL + V++++KAT  +LW  DLDALERE
Sbjct: 1067 QKVRATDYEYLLSMAIGTLTLEKVQELCADRDKLNKGVDDLKKATPKALWITDLDALERE 1126

Query: 950  LDEQDRRDALTEEEAMEIKAKT-----RKASKPATKNPRKNNKKISKTESAAEPMEISTN 786
            LDEQD+ DA  EE   ++K++       K S+ A KNPRKNNKK +  E AAE M++S +
Sbjct: 1127 LDEQDKNDARAEETRKQLKSRVMSEAGMKVSRQAPKNPRKNNKKANNAEPAAETMDVSAS 1186

Query: 785  SEIETVSANVGPFPPSDNARVVVQKKAPRKGKSVAALKXXXXXXXXEILALNERIAAYNL 606
            S +E  S      P    A     +KAP K K +            E+  L ER+AAYNL
Sbjct: 1187 SAMEMESVPEVVKPKGRAA----PRKAPAKKKEMPT-SVLKDEDDDEVHELKERLAAYNL 1241

Query: 605  DSSPDHAEAPESEVSEV-QIKNKGPTRKAAATKKPLSTVTXXXXXXXXXXXXXXEVMPAE 429
            +SSPD + A E+EV +V   + K P+R+AAA KKPL++ T              E + A 
Sbjct: 1242 ESSPDGSAAMEAEVPQVPAARKKEPSRRAAAQKKPLASFTEISDDDEDDEDFEVEEVSAS 1301

Query: 428  E------XXXXXXXXXXXXXXXXXXXXXKRGPASKKS-QILGQKLITEVLQGAAD---SP 279
            +                           KRG A+K+  Q+LGQ L+TE+ + A     SP
Sbjct: 1302 DVKKKGGRKPAANAKAAAAKPAAAAAKNKRGAANKQQPQLLGQTLLTEIFKPAETLGISP 1361

Query: 278  DKKVRKIRISPFNKKSGSVLG-------RXXXXXXXXXXXXXXXXXXESNQVVVP-RARP 123
            +KKVRK+R SPFNKKSGSVLG                          ESN+VV+P R RP
Sbjct: 1362 EKKVRKMRASPFNKKSGSVLGSTGEEDETAETEENSGSASTSNSSGGESNEVVMPARTRP 1421

Query: 122  QRANSRKATYVL 87
            QR N  +  YV+
Sbjct: 1422 QRENRVQTRYVV 1433


>ref|XP_010023678.1| PREDICTED: DNA topoisomerase 2-like [Eucalyptus grandis]
            gi|629094018|gb|KCW60013.1| hypothetical protein
            EUGRSUZ_H02748 [Eucalyptus grandis]
          Length = 1496

 Score =  222 bits (565), Expect = 5e-55
 Identities = 152/392 (38%), Positives = 212/392 (54%), Gaps = 19/392 (4%)
 Frame = -1

Query: 1205 TTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNRDKLI 1026
            T E +VAGSTD  EETEENS+  T++GV+ASDYEYLLSM+IG+LT+EKVQELC ++DKL+
Sbjct: 1096 TIETAVAGSTDDAEETEENSE-PTTKGVKASDYEYLLSMAIGALTLEKVQELCADKDKLV 1154

Query: 1025 QEVEEMRKATINSLWTKDLDALERELDEQDRRDALTEEEAMEIKAKTR------KASKPA 864
             EV+ +RKAT  +LW +DL ALE +LDEQ++ DA  EE     KA+++      K S+ A
Sbjct: 1155 DEVDALRKATPENLWLEDLAALEEKLDEQEKMDAQAEETR---KARSKANGVGTKVSRQA 1211

Query: 863  TKNPRKNNKKISKTESAAEPMEISTNSEIETVSANVGPFPPSDNARVVVQKKAPRKGKSV 684
             K PRKN+ K +  E+ A   E++  S +   + N              +  AP+  KS 
Sbjct: 1212 PKKPRKNDTKANNPEAQA---EVTQGSTVTLEAGNAADVAKPKRGAGARKAPAPKPSKSA 1268

Query: 683  AALKXXXXXXXXEILALNERIAAYNLDSSPDHAEAPESEVSEVQIKNKGPTRKAAATKKP 504
            +           E+L L ER+AAYNL+SSPD++ A E +V E+ +K K P+++AA  KKP
Sbjct: 1269 SV---SDDDEDFEMLDLKERLAAYNLESSPDNSSALEDKVPEIPVKEKEPSKRAATRKKP 1325

Query: 503  ---LSTVTXXXXXXXXXXXXXXEV-MPAEEXXXXXXXXXXXXXXXXXXXXXKRGPASKKS 336
               LS ++               V   AE                       +   + + 
Sbjct: 1326 SVILSEISEEENSNDSGDDDYETVDSEAEVAKKKGGRKPSAAAKKSKPPAATKKGQANRQ 1385

Query: 335  QILG--QKLITEVLQGAAD---SPDKKVRKIRISPFNKKSGSVLGRXXXXXXXXXXXXXX 171
            Q  G  Q+L+TE+L+ A     SP+KKVRK+R SPFNKKS S+LG+              
Sbjct: 1386 QARGTSQRLLTEMLKPAESTGVSPEKKVRKMRASPFNKKSSSLLGKEGKADSSTSEEMSS 1445

Query: 170  XXXXESNQVVV----PRARPQRANSRKATYVL 87
                   + VV    P+ RPQR N ++ TYVL
Sbjct: 1446 NPMSNDGEDVVEVAPPKRRPQRVNRKQTTYVL 1477


>ref|XP_002314046.2| DNA topoisomerase family protein [Populus trichocarpa]
            gi|550331162|gb|EEE88001.2| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 1482

 Score =  221 bits (563), Expect = 8e-55
 Identities = 159/391 (40%), Positives = 213/391 (54%), Gaps = 23/391 (5%)
 Frame = -1

Query: 1190 VAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNRDKLIQEVEE 1011
            VAG+TD  EE E++ D++   GVRASDY+YLLSM+IG+LT+E+VQ+LC +RDKL  EV+ 
Sbjct: 1086 VAGATDDTEEAEDSPDVS---GVRASDYDYLLSMAIGTLTLERVQQLCADRDKLNGEVDS 1142

Query: 1010 MRKATINSLWTKDLDALERELDEQDRRDALTEEEAMEIK---AKTR---KASKPATKNPR 849
            +RK T   LW KDL+ALE +LD  D  DA  EE   ++K   AK     K SK A K PR
Sbjct: 1143 LRKTTPKVLWVKDLEALEMQLDMLDEYDAEAEEARRKLKGGGAKGEAGFKVSKQAPKYPR 1202

Query: 848  KNNKKISKTESAAEPMEISTNSEIETVSANVGPFPPSDNARVVVQ-------KKAPRKGK 690
            KN KK    E + E    S++  IET S        S+NA  VV+       KKAP K +
Sbjct: 1203 KNTKKAINEEVSVETTGTSSSFAIETAS--------SENAAAVVKPKGRAGSKKAPAKME 1254

Query: 689  SVAALKXXXXXXXXEILALNERIAAYNLDSSPDHAEAPESEVSEVQIKNKGPTRKAAATK 510
             ++ +         EI +L +R+ AY LDSSP+ +   E++V +V      P R+ AA K
Sbjct: 1255 KLSPV-LDDFDEDDEIESLKDRLNAYRLDSSPEQSADMETDVLQV------PARRGAARK 1307

Query: 509  KPLSTVT------XXXXXXXXXXXXXXEVMPAEEXXXXXXXXXXXXXXXXXXXXXKRGPA 348
            KPL+ V+                     +   ++                     +RGPA
Sbjct: 1308 KPLANVSVISDSEDEPNLDDDADVEVKALPETKKKGGRKAAAANDKAAKPPAATKRRGPA 1367

Query: 347  SKKSQILGQKLITEVL---QGAADSPDKKVRKIRISPFNKKSGSVLGRXXXXXXXXXXXX 177
            S++SQ LGQKL+TE+L   +GA  SP+KKVRK+R SPFNKKSGSVLGR            
Sbjct: 1368 SQQSQGLGQKLLTEMLKPAEGAGISPEKKVRKVRASPFNKKSGSVLGRIHKEDDTGSEPM 1427

Query: 176  XXXXXXESNQVVVP-RARPQRANSRKATYVL 87
                   ++ + VP RARPQRAN ++  YVL
Sbjct: 1428 SASSSENTDVIDVPARARPQRANRKQTRYVL 1458