BLASTX nr result
ID: Forsythia21_contig00036337
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Forsythia21_contig00036337
(320 letters)
Database: ./nr
69,698,275 sequences; 24,982,196,650 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gb|KIW21312.1| scytalone dehydratase [Exophiala spinifera] 79 1e-20
gb|KIX01361.1| scytalone dehydratase [Rhinocladiella mackenziei ... 82 1e-20
ref|XP_007737378.1| scytalone dehydratase [Capronia epimyces CBS... 81 2e-20
gb|EKG18496.1| Scytalone dehydratase [Macrophomina phaseolina MS6] 80 3e-20
ref|XP_007724583.1| scytalone dehydratase [Capronia coronata CBS... 80 4e-20
gb|KIW41835.1| scytalone dehydratase [Exophiala oligosperma] 78 9e-20
gb|KIW50816.1| scytalone dehydratase [Exophiala xenobiotica] 78 3e-19
gb|KIV77451.1| hypothetical protein PV11_09245 [Exophiala sideris] 79 2e-18
ref|XP_001908532.1| hypothetical protein [Podospora anserina S m... 70 2e-14
ref|XP_962944.1| scytalone dehydratase [Neurospora crassa OR74A]... 69 6e-14
ref|XP_009850511.1| scytalone dehydratase [Neurospora tetrasperm... 69 1e-13
ref|XP_003350389.1| scytalone dehydratase [Sordaria macrospora k... 68 1e-13
ref|XP_007925880.1| hypothetical protein MYCFIDRAFT_58137 [Pseud... 82 2e-13
ref|XP_003712572.1| scytalone dehydratase [Magnaporthe oryzae 70... 71 8e-13
ref|XP_001221619.1| hypothetical protein CHGG_05524 [Chaetomium ... 61 8e-13
pdb|3STD|A Chain A, Scytalone Dehydratase And Cyanocinnoline Inh... 71 8e-13
pdb|4STD|A Chain A, High Resolution Structures Of Scytalone Dehy... 71 8e-13
ref|XP_001801786.1| hypothetical protein SNOG_11546 [Phaeosphaer... 79 9e-13
gb|EME46236.1| hypothetical protein DOTSEDRAFT_70291 [Dothistrom... 79 1e-12
gb|EMF14379.1| Scytalone dehydratase complexed with tight-bindin... 79 2e-12
>gb|KIW21312.1| scytalone dehydratase [Exophiala spinifera]
Length = 199
Score = 79.0 bits (193), Expect(2) = 1e-20
Identities = 32/39 (82%), Positives = 36/39 (92%)
Frame = -1
Query: 320 DETRSHILVKGHAHSYNIHWYKKVNGVWKFAGLNPDIRW 204
D +R+ I VKGHAHSYN+HWYKKV+GVWKFAGLNPDIRW
Sbjct: 127 DASRTKIKVKGHAHSYNLHWYKKVDGVWKFAGLNPDIRW 165
Score = 47.0 bits (110), Expect(2) = 1e-20
Identities = 25/41 (60%), Positives = 29/41 (70%), Gaps = 6/41 (14%)
Frame = -3
Query: 225 LEP*YQVAEYDFDKVFAEGRDELGE------AKQAAGIPAE 121
L P + EYDFDKVFAEGR+ELGE A++A GIPAE
Sbjct: 159 LNPDIRWGEYDFDKVFAEGREELGEDEAKKVAQEAQGIPAE 199
>gb|KIX01361.1| scytalone dehydratase [Rhinocladiella mackenziei CBS 650.93]
Length = 185
Score = 82.4 bits (202), Expect(2) = 1e-20
Identities = 34/39 (87%), Positives = 37/39 (94%)
Frame = -1
Query: 320 DETRSHILVKGHAHSYNIHWYKKVNGVWKFAGLNPDIRW 204
D TR+ ILVKGHAHSYN+HWYKKV+GVWKFAGLNPDIRW
Sbjct: 112 DATRTKILVKGHAHSYNMHWYKKVDGVWKFAGLNPDIRW 150
Score = 43.5 bits (101), Expect(2) = 1e-20
Identities = 23/40 (57%), Positives = 27/40 (67%), Gaps = 7/40 (17%)
Frame = -3
Query: 225 LEP*YQVAEYDFDKVFAEGRDELGE-------AKQAAGIP 127
L P + EYDFDKVFA+GR+ELGE AK+A GIP
Sbjct: 144 LNPDIRWGEYDFDKVFADGREELGEKEEAEKLAKEAQGIP 183
>ref|XP_007737378.1| scytalone dehydratase [Capronia epimyces CBS 606.96]
gi|590002716|gb|EXJ77933.1| scytalone dehydratase
[Capronia epimyces CBS 606.96]
Length = 188
Score = 80.9 bits (198), Expect(2) = 2e-20
Identities = 33/39 (84%), Positives = 36/39 (92%)
Frame = -1
Query: 320 DETRSHILVKGHAHSYNIHWYKKVNGVWKFAGLNPDIRW 204
DETRS +LVKGHAHS N HWYKK++GVWKFAGLNPDIRW
Sbjct: 112 DETRSKVLVKGHAHSSNTHWYKKIDGVWKFAGLNPDIRW 150
Score = 44.7 bits (104), Expect(2) = 2e-20
Identities = 24/45 (53%), Positives = 29/45 (64%), Gaps = 10/45 (22%)
Frame = -3
Query: 225 LEP*YQVAEYDFDKVFAEGRDELGE----------AKQAAGIPAE 121
L P + EYDFDKVFA+GR+ELG+ AK+A GIPAE
Sbjct: 144 LNPDIRWGEYDFDKVFADGREELGDKEKAEEADKVAKEAQGIPAE 188
>gb|EKG18496.1| Scytalone dehydratase [Macrophomina phaseolina MS6]
Length = 189
Score = 79.7 bits (195), Expect(2) = 3e-20
Identities = 33/39 (84%), Positives = 35/39 (89%)
Frame = -1
Query: 320 DETRSHILVKGHAHSYNIHWYKKVNGVWKFAGLNPDIRW 204
DETR+ + VKGHAHS N HWYKKVNGVWKFAGLNPDIRW
Sbjct: 110 DETRTTVAVKGHAHSTNTHWYKKVNGVWKFAGLNPDIRW 148
Score = 45.4 bits (106), Expect(2) = 3e-20
Identities = 21/33 (63%), Positives = 22/33 (66%)
Frame = -3
Query: 225 LEP*YQVAEYDFDKVFAEGRDELGEAKQAAGIP 127
L P + EYDFDKVFA GRDE GE K GIP
Sbjct: 142 LNPDIRWGEYDFDKVFASGRDEFGETKAVEGIP 174
>ref|XP_007724583.1| scytalone dehydratase [Capronia coronata CBS 617.96]
gi|590013374|gb|EXJ88577.1| scytalone dehydratase
[Capronia coronata CBS 617.96]
Length = 188
Score = 79.7 bits (195), Expect(2) = 4e-20
Identities = 32/39 (82%), Positives = 36/39 (92%)
Frame = -1
Query: 320 DETRSHILVKGHAHSYNIHWYKKVNGVWKFAGLNPDIRW 204
DETR+ +LVKGHAHS N HWYKK++GVWKFAGLNPDIRW
Sbjct: 112 DETRTKVLVKGHAHSSNTHWYKKIDGVWKFAGLNPDIRW 150
Score = 44.7 bits (104), Expect(2) = 4e-20
Identities = 24/45 (53%), Positives = 29/45 (64%), Gaps = 10/45 (22%)
Frame = -3
Query: 225 LEP*YQVAEYDFDKVFAEGRDELGE----------AKQAAGIPAE 121
L P + EYDFDKVFA+GR+ELG+ AK+A GIPAE
Sbjct: 144 LNPDIRWGEYDFDKVFADGREELGDQEKAEEAEKVAKEAQGIPAE 188
>gb|KIW41835.1| scytalone dehydratase [Exophiala oligosperma]
Length = 183
Score = 78.2 bits (191), Expect(2) = 9e-20
Identities = 31/39 (79%), Positives = 36/39 (92%)
Frame = -1
Query: 320 DETRSHILVKGHAHSYNIHWYKKVNGVWKFAGLNPDIRW 204
D +R+ + VKGHAHSYN+HWYKKV+GVWKFAGLNPDIRW
Sbjct: 111 DASRTKVKVKGHAHSYNMHWYKKVDGVWKFAGLNPDIRW 149
Score = 45.1 bits (105), Expect(2) = 9e-20
Identities = 24/40 (60%), Positives = 28/40 (70%), Gaps = 6/40 (15%)
Frame = -3
Query: 225 LEP*YQVAEYDFDKVFAEGRDELGE------AKQAAGIPA 124
L P + EYDFDKVFAEGR+ELGE A++A GIPA
Sbjct: 143 LNPDIRWGEYDFDKVFAEGREELGEEEAKKVAQEAQGIPA 182
>gb|KIW50816.1| scytalone dehydratase [Exophiala xenobiotica]
Length = 184
Score = 78.2 bits (191), Expect(2) = 3e-19
Identities = 31/39 (79%), Positives = 36/39 (92%)
Frame = -1
Query: 320 DETRSHILVKGHAHSYNIHWYKKVNGVWKFAGLNPDIRW 204
D +R+ I VKGHAHSYN+HWYKK++GVWKFAGLNPDIRW
Sbjct: 112 DASRTKIKVKGHAHSYNMHWYKKIDGVWKFAGLNPDIRW 150
Score = 43.5 bits (101), Expect(2) = 3e-19
Identities = 23/39 (58%), Positives = 27/39 (69%), Gaps = 6/39 (15%)
Frame = -3
Query: 225 LEP*YQVAEYDFDKVFAEGRDELGE------AKQAAGIP 127
L P + EYDFDKVFAEGR+ELGE A++A GIP
Sbjct: 144 LNPDIRWGEYDFDKVFAEGREELGEEEAKKVAQEAQGIP 182
>gb|KIV77451.1| hypothetical protein PV11_09245 [Exophiala sideris]
Length = 227
Score = 79.3 bits (194), Expect(2) = 2e-18
Identities = 32/39 (82%), Positives = 36/39 (92%)
Frame = -1
Query: 320 DETRSHILVKGHAHSYNIHWYKKVNGVWKFAGLNPDIRW 204
D +R+ I VKGHAHSYN+HWYKKV+GVWKFAGLNPDIRW
Sbjct: 151 DASRAQIKVKGHAHSYNLHWYKKVDGVWKFAGLNPDIRW 189
Score = 39.3 bits (90), Expect(2) = 2e-18
Identities = 20/45 (44%), Positives = 28/45 (62%), Gaps = 10/45 (22%)
Frame = -3
Query: 225 LEP*YQVAEYDFDKVFAEGRDELGE----------AKQAAGIPAE 121
L P + E+DFD+VF EGR+ELG+ AKQA G+P++
Sbjct: 183 LNPDIRWGEFDFDRVFEEGREELGDKEKAEEADKLAKQAEGVPSK 227
>ref|XP_001908532.1| hypothetical protein [Podospora anserina S mat+]
gi|170943552|emb|CAP69205.1| unnamed protein product
[Podospora anserina S mat+] gi|681103228|emb|CDP32686.1|
Putative scytalone dehydratase [Podospora anserina S
mat+]
Length = 171
Score = 70.5 bits (171), Expect(2) = 2e-14
Identities = 29/39 (74%), Positives = 34/39 (87%)
Frame = -1
Query: 320 DETRSHILVKGHAHSYNIHWYKKVNGVWKFAGLNPDIRW 204
D + S + VKGHAHS+N H+YKKVNGVWKFAGLNP+IRW
Sbjct: 114 DSSLSKVEVKGHAHSHNTHYYKKVNGVWKFAGLNPNIRW 152
Score = 35.0 bits (79), Expect(2) = 2e-14
Identities = 16/25 (64%), Positives = 17/25 (68%)
Frame = -3
Query: 225 LEP*YQVAEYDFDKVFAEGRDELGE 151
L P + EYDFDKVFA GRD GE
Sbjct: 146 LNPNIRWFEYDFDKVFASGRDNFGE 170
>ref|XP_962944.1| scytalone dehydratase [Neurospora crassa OR74A]
gi|28924589|gb|EAA33708.1| scytalone dehydratase
[Neurospora crassa OR74A] gi|725981537|gb|KHE84649.1|
scytalone dehydratase [Neurospora crassa]
Length = 174
Score = 68.9 bits (167), Expect(2) = 6e-14
Identities = 27/39 (69%), Positives = 33/39 (84%)
Frame = -1
Query: 320 DETRSHILVKGHAHSYNIHWYKKVNGVWKFAGLNPDIRW 204
D + + + V GHAHS+N H+YKK+NGVWKFAGLNPDIRW
Sbjct: 116 DSSCTKVAVTGHAHSHNTHYYKKINGVWKFAGLNPDIRW 154
Score = 34.7 bits (78), Expect(2) = 6e-14
Identities = 16/25 (64%), Positives = 19/25 (76%)
Frame = -3
Query: 225 LEP*YQVAEYDFDKVFAEGRDELGE 151
L P + E DFDKVFA+GR+ELGE
Sbjct: 148 LNPDIRWTEGDFDKVFADGREELGE 172
>ref|XP_009850511.1| scytalone dehydratase [Neurospora tetrasperma FGSC 2508]
gi|336469226|gb|EGO57388.1| scytalone dehydratase
[Neurospora tetrasperma FGSC 2508]
gi|350291142|gb|EGZ72356.1| scytalone dehydratase
[Neurospora tetrasperma FGSC 2509]
Length = 174
Score = 68.9 bits (167), Expect(2) = 1e-13
Identities = 27/39 (69%), Positives = 33/39 (84%)
Frame = -1
Query: 320 DETRSHILVKGHAHSYNIHWYKKVNGVWKFAGLNPDIRW 204
D + + + V GHAHS+N H+YKK+NGVWKFAGLNPDIRW
Sbjct: 116 DSSCTKVAVTGHAHSHNTHYYKKINGVWKFAGLNPDIRW 154
Score = 33.9 bits (76), Expect(2) = 1e-13
Identities = 16/26 (61%), Positives = 19/26 (73%)
Frame = -3
Query: 225 LEP*YQVAEYDFDKVFAEGRDELGEA 148
L P + E DFD VFA+GR+ELGEA
Sbjct: 148 LNPDIRWTEGDFDMVFADGREELGEA 173
>ref|XP_003350389.1| scytalone dehydratase [Sordaria macrospora k-hell]
gi|380090912|emb|CCC11445.1| scytalone dehydratase
[Sordaria macrospora k-hell]
Length = 174
Score = 67.8 bits (164), Expect(2) = 1e-13
Identities = 27/39 (69%), Positives = 34/39 (87%)
Frame = -1
Query: 320 DETRSHILVKGHAHSYNIHWYKKVNGVWKFAGLNPDIRW 204
D++ + + V GHAHS+N H+YKKV+GVWKFAGLNPDIRW
Sbjct: 116 DKSCTKVAVTGHAHSHNTHYYKKVDGVWKFAGLNPDIRW 154
Score = 34.7 bits (78), Expect(2) = 1e-13
Identities = 16/25 (64%), Positives = 19/25 (76%)
Frame = -3
Query: 225 LEP*YQVAEYDFDKVFAEGRDELGE 151
L P + E DFDKVFA+GR+ELGE
Sbjct: 148 LNPDIRWTEGDFDKVFADGREELGE 172
>ref|XP_007925880.1| hypothetical protein MYCFIDRAFT_58137 [Pseudocercospora fijiensis
CIRAD86] gi|452982864|gb|EME82622.1| hypothetical
protein MYCFIDRAFT_58137 [Pseudocercospora fijiensis
CIRAD86]
Length = 195
Score = 81.6 bits (200), Expect = 2e-13
Identities = 33/39 (84%), Positives = 36/39 (92%)
Frame = -1
Query: 320 DETRSHILVKGHAHSYNIHWYKKVNGVWKFAGLNPDIRW 204
DET S + VKGHAHS+N+HWYKKVNGVWKFAGLNPDIRW
Sbjct: 119 DETLSKVAVKGHAHSFNLHWYKKVNGVWKFAGLNPDIRW 157
>ref|XP_003712572.1| scytalone dehydratase [Magnaporthe oryzae 70-15]
gi|3024596|sp|P56221.1|SCYD_MAGO7 RecName:
Full=Scytalone dehydratase [Magnaporthe oryzae 70-15]
gi|157833862|pdb|1STD|A Chain A, Crystal Structure Of
Scytalone Dehydratase: A Disease Determinant Of The Rice
Pathogen, Magnaporthe Grisea gi|157836372|pdb|2STD|A
Chain A, Scytalone Dehydratase Complexed With
Tight-Binding Inhibitor Carpropamid
gi|3798734|dbj|BAA34046.1| scytalone dehydratase
[Magnaporthe grisea] gi|351644904|gb|EHA52765.1|
scytalone dehydratase [Magnaporthe oryzae 70-15]
gi|440474360|gb|ELQ43109.1| scytalone dehydratase
[Magnaporthe oryzae Y34] gi|440488405|gb|ELQ68132.1|
scytalone dehydratase [Magnaporthe oryzae P131]
Length = 172
Score = 70.9 bits (172), Expect(2) = 8e-13
Identities = 27/39 (69%), Positives = 32/39 (82%)
Frame = -1
Query: 320 DETRSHILVKGHAHSYNIHWYKKVNGVWKFAGLNPDIRW 204
D T + +KGHAHS N+HWYKK++GVWKFAGL PDIRW
Sbjct: 115 DTTMKEVTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRW 153
Score = 28.9 bits (63), Expect(2) = 8e-13
Identities = 10/25 (40%), Positives = 18/25 (72%)
Frame = -3
Query: 225 LEP*YQVAEYDFDKVFAEGRDELGE 151
L+P + E+DFD++F +GR+ G+
Sbjct: 147 LKPDIRWGEFDFDRIFEDGRETFGD 171
>ref|XP_001221619.1| hypothetical protein CHGG_05524 [Chaetomium globosum CBS 148.51]
gi|88181437|gb|EAQ88905.1| hypothetical protein
CHGG_05524 [Chaetomium globosum CBS 148.51]
Length = 172
Score = 61.2 bits (147), Expect(2) = 8e-13
Identities = 24/39 (61%), Positives = 30/39 (76%)
Frame = -1
Query: 320 DETRSHILVKGHAHSYNIHWYKKVNGVWKFAGLNPDIRW 204
D + ++ VKGHAH +N H+Y KV GVWKFAGL+P IRW
Sbjct: 114 DASLQNVEVKGHAHGFNTHYYNKVGGVWKFAGLSPTIRW 152
Score = 38.5 bits (88), Expect(2) = 8e-13
Identities = 17/27 (62%), Positives = 20/27 (74%)
Frame = -3
Query: 225 LEP*YQVAEYDFDKVFAEGRDELGEAK 145
L P + +EYDFDKVFA GRD GE+K
Sbjct: 146 LSPTIRWSEYDFDKVFASGRDNFGESK 172
>pdb|3STD|A Chain A, Scytalone Dehydratase And Cyanocinnoline Inhibitor
gi|6435663|pdb|3STD|B Chain B, Scytalone Dehydratase And
Cyanocinnoline Inhibitor gi|6435664|pdb|3STD|C Chain C,
Scytalone Dehydratase And Cyanocinnoline Inhibitor
Length = 165
Score = 70.9 bits (172), Expect(2) = 8e-13
Identities = 27/39 (69%), Positives = 32/39 (82%)
Frame = -1
Query: 320 DETRSHILVKGHAHSYNIHWYKKVNGVWKFAGLNPDIRW 204
D T + +KGHAHS N+HWYKK++GVWKFAGL PDIRW
Sbjct: 108 DTTMKEVTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRW 146
Score = 28.9 bits (63), Expect(2) = 8e-13
Identities = 10/25 (40%), Positives = 18/25 (72%)
Frame = -3
Query: 225 LEP*YQVAEYDFDKVFAEGRDELGE 151
L+P + E+DFD++F +GR+ G+
Sbjct: 140 LKPDIRWGEFDFDRIFEDGRETFGD 164
>pdb|4STD|A Chain A, High Resolution Structures Of Scytalone
Dehydratase-Inhibitor Complexes Crystallized At
Physiological Ph gi|6730613|pdb|4STD|B Chain B, High
Resolution Structures Of Scytalone Dehydratase-Inhibitor
Complexes Crystallized At Physiological Ph
gi|6730614|pdb|4STD|C Chain C, High Resolution
Structures Of Scytalone Dehydratase-Inhibitor Complexes
Crystallized At Physiological Ph gi|6730615|pdb|5STD|A
Chain A, Scytalone Dehydratase Plus Inhibitor 2
gi|6730616|pdb|5STD|B Chain B, Scytalone Dehydratase
Plus Inhibitor 2 gi|6730617|pdb|5STD|C Chain C,
Scytalone Dehydratase Plus Inhibitor 2
gi|6730622|pdb|6STD|A Chain A, Scytalone Dehydratase
Plus Inhibitor 3 gi|6730623|pdb|6STD|B Chain B,
Scytalone Dehydratase Plus Inhibitor 3
gi|6730624|pdb|6STD|C Chain C, Scytalone Dehydratase
Plus Inhibitor 3 gi|6730625|pdb|7STD|A Chain A,
Scytalone Dehydratase Plus Inhibitor 4
gi|6730626|pdb|7STD|B Chain B, Scytalone Dehydratase
Plus Inhibitor 4 gi|6730627|pdb|7STD|C Chain C,
Scytalone Dehydratase Plus Inhibitor 4
Length = 164
Score = 70.9 bits (172), Expect(2) = 8e-13
Identities = 27/39 (69%), Positives = 32/39 (82%)
Frame = -1
Query: 320 DETRSHILVKGHAHSYNIHWYKKVNGVWKFAGLNPDIRW 204
D T + +KGHAHS N+HWYKK++GVWKFAGL PDIRW
Sbjct: 107 DTTMKEVTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRW 145
Score = 28.9 bits (63), Expect(2) = 8e-13
Identities = 10/25 (40%), Positives = 18/25 (72%)
Frame = -3
Query: 225 LEP*YQVAEYDFDKVFAEGRDELGE 151
L+P + E+DFD++F +GR+ G+
Sbjct: 139 LKPDIRWGEFDFDRIFEDGRETFGD 163
>ref|XP_001801786.1| hypothetical protein SNOG_11546 [Phaeosphaeria nodorum SN15]
gi|160703252|gb|EAT81254.2| hypothetical protein
SNOG_11546 [Phaeosphaeria nodorum SN15]
Length = 114
Score = 79.3 bits (194), Expect = 9e-13
Identities = 32/39 (82%), Positives = 36/39 (92%)
Frame = -1
Query: 320 DETRSHILVKGHAHSYNIHWYKKVNGVWKFAGLNPDIRW 204
DET S +LVKGHAHS+N+HWYKKV+G WKFAGLNPDIRW
Sbjct: 47 DETMSKVLVKGHAHSFNMHWYKKVDGEWKFAGLNPDIRW 85
>gb|EME46236.1| hypothetical protein DOTSEDRAFT_70291 [Dothistroma septosporum
NZE10]
Length = 195
Score = 79.0 bits (193), Expect = 1e-12
Identities = 30/39 (76%), Positives = 36/39 (92%)
Frame = -1
Query: 320 DETRSHILVKGHAHSYNIHWYKKVNGVWKFAGLNPDIRW 204
DE+ + + VKGHAHS+N+HWYKK+NGVWKFAGLNPDIRW
Sbjct: 124 DESMTEVTVKGHAHSFNMHWYKKINGVWKFAGLNPDIRW 162
>gb|EMF14379.1| Scytalone dehydratase complexed with tight-binding inhibitor
Carpropamid [Sphaerulina musiva SO2202]
Length = 202
Score = 78.6 bits (192), Expect = 2e-12
Identities = 31/39 (79%), Positives = 36/39 (92%)
Frame = -1
Query: 320 DETRSHILVKGHAHSYNIHWYKKVNGVWKFAGLNPDIRW 204
DET + ++VKGHAHSYN HWYKK+NGVWKFAGLNP+IRW
Sbjct: 119 DETCTTVMVKGHAHSYNHHWYKKINGVWKFAGLNPEIRW 157