BLASTX nr result
ID: Forsythia21_contig00019767
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Forsythia21_contig00019767
(665 letters)
Database: ./nr
69,698,275 sequences; 24,982,196,650 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|XP_012857856.1| PREDICTED: vacuolar-processing enzyme-like [... 205 2e-50
ref|XP_012847061.1| PREDICTED: vacuolar-processing enzyme-like [... 194 4e-47
ref|XP_003525979.1| PREDICTED: vacuolar-processing enzyme-like [... 192 1e-46
emb|CDP08231.1| unnamed protein product [Coffea canephora] 191 3e-46
emb|CAH59407.1| endopeptidase 1 [Plantago major] 190 7e-46
gb|KHN29737.1| Vacuolar-processing enzyme [Glycine soja] 189 9e-46
ref|XP_009616670.1| PREDICTED: vacuolar-processing enzyme-like [... 189 2e-45
ref|XP_009337146.1| PREDICTED: vacuolar-processing enzyme-like [... 188 2e-45
ref|XP_009361606.1| PREDICTED: vacuolar-processing enzyme-like [... 188 3e-45
ref|XP_006578073.1| PREDICTED: vacuolar-processing enzyme-like [... 188 3e-45
dbj|BAC86022.1| unnamed protein product [Homo sapiens] 188 3e-45
ref|XP_008393660.1| PREDICTED: vacuolar-processing enzyme [Malus... 186 7e-45
ref|XP_002516472.1| Vacuolar-processing enzyme precursor, putati... 186 7e-45
gb|AGC94759.1| vacuolar processing enzyme [Malus micromalus] 186 7e-45
gb|AGC94758.1| vacuolar processing enzyme [Malus hupehensis] 186 7e-45
gb|AGC94756.1| vacuolar processing enzyme [Malus sieversii] 186 7e-45
gb|ACR24644.1| vacuolar processing enzyme [Malus hupehensis var.... 186 7e-45
ref|XP_011019533.1| PREDICTED: vacuolar-processing enzyme isofor... 186 1e-44
ref|XP_011019532.1| PREDICTED: vacuolar-processing enzyme isofor... 186 1e-44
gb|ACQ91103.1| vacuolar processing enzyme a [Populus tomentosa] 186 1e-44
>ref|XP_012857856.1| PREDICTED: vacuolar-processing enzyme-like [Erythranthe guttatus]
gi|604300561|gb|EYU20379.1| hypothetical protein
MIMGU_mgv1a005412mg [Erythranthe guttata]
Length = 484
Score = 205 bits (521), Expect = 2e-50
Identities = 94/108 (87%), Positives = 103/108 (95%)
Frame = -1
Query: 665 MAHRTHIDSSIKLVGKILFGIEKGPDMLKNIRPTGQPLVDDWDCLKSLVRTFETHCGSLS 486
MAHRTH+DSSIKL+GK+LFGI+KGP MLK +RP+GQPLVDDWDCLKSLVRTFETHCGSLS
Sbjct: 377 MAHRTHVDSSIKLIGKLLFGIDKGPQMLKAMRPSGQPLVDDWDCLKSLVRTFETHCGSLS 436
Query: 485 QYGMKHMRSIANICNAGIKQEQMAEASGQACVSFPSSSWSSLHMGFSA 342
QYGMKHMRSIANICNAG+ +EQMAEASGQAC SFPS+SWSSLH GFSA
Sbjct: 437 QYGMKHMRSIANICNAGVTREQMAEASGQACTSFPSNSWSSLHRGFSA 484
>ref|XP_012847061.1| PREDICTED: vacuolar-processing enzyme-like [Erythranthe guttatus]
gi|604317236|gb|EYU29312.1| hypothetical protein
MIMGU_mgv1a005315mg [Erythranthe guttata]
Length = 489
Score = 194 bits (493), Expect = 4e-47
Identities = 89/108 (82%), Positives = 97/108 (89%)
Frame = -1
Query: 665 MAHRTHIDSSIKLVGKILFGIEKGPDMLKNIRPTGQPLVDDWDCLKSLVRTFETHCGSLS 486
MAHRTHID+SIKL+GK+LFG +KGP +LK +RP G+PLVDDW CLKSLVRTFETHCGSLS
Sbjct: 382 MAHRTHIDNSIKLIGKLLFGFQKGPQVLKTVRPAGKPLVDDWTCLKSLVRTFETHCGSLS 441
Query: 485 QYGMKHMRSIANICNAGIKQEQMAEASGQACVSFPSSSWSSLHMGFSA 342
QYGMKHMRSIANICNAG+ EQMAE S QAC SFPSSSWSSLH GFSA
Sbjct: 442 QYGMKHMRSIANICNAGVSIEQMAEVSAQACTSFPSSSWSSLHRGFSA 489
>ref|XP_003525979.1| PREDICTED: vacuolar-processing enzyme-like [Glycine max]
gi|734402751|gb|KHN32223.1| Vacuolar-processing enzyme
[Glycine soja]
Length = 484
Score = 192 bits (489), Expect = 1e-46
Identities = 86/108 (79%), Positives = 99/108 (91%)
Frame = -1
Query: 665 MAHRTHIDSSIKLVGKILFGIEKGPDMLKNIRPTGQPLVDDWDCLKSLVRTFETHCGSLS 486
M+HR HID ++KL+GK+LFGIEKGP++L ++RP GQPLVDDWDCLK+LVRTFETHCGSLS
Sbjct: 377 MSHRMHIDDNMKLIGKLLFGIEKGPELLSSVRPAGQPLVDDWDCLKTLVRTFETHCGSLS 436
Query: 485 QYGMKHMRSIANICNAGIKQEQMAEASGQACVSFPSSSWSSLHMGFSA 342
QYGMKHMRS AN CNAGI++EQMAEAS QACVS P+SSWSSLH GFSA
Sbjct: 437 QYGMKHMRSFANFCNAGIRKEQMAEASAQACVSIPASSWSSLHRGFSA 484
>emb|CDP08231.1| unnamed protein product [Coffea canephora]
Length = 488
Score = 191 bits (485), Expect = 3e-46
Identities = 86/108 (79%), Positives = 99/108 (91%)
Frame = -1
Query: 665 MAHRTHIDSSIKLVGKILFGIEKGPDMLKNIRPTGQPLVDDWDCLKSLVRTFETHCGSLS 486
M+HR HID+S+KL+GK+LFGIEKG ++L ++RP G PL DDWDCLKSLVRTFETHCGSLS
Sbjct: 381 MSHRMHIDNSVKLIGKLLFGIEKGSEILNSVRPAGHPLADDWDCLKSLVRTFETHCGSLS 440
Query: 485 QYGMKHMRSIANICNAGIKQEQMAEASGQACVSFPSSSWSSLHMGFSA 342
QYGMKHMRSIANICNAGIK++QMAEA+ QACVS PS+SWSSLH GFSA
Sbjct: 441 QYGMKHMRSIANICNAGIKKDQMAEAAAQACVSLPSNSWSSLHRGFSA 488
>emb|CAH59407.1| endopeptidase 1 [Plantago major]
Length = 165
Score = 190 bits (482), Expect = 7e-46
Identities = 86/108 (79%), Positives = 98/108 (90%)
Frame = -1
Query: 665 MAHRTHIDSSIKLVGKILFGIEKGPDMLKNIRPTGQPLVDDWDCLKSLVRTFETHCGSLS 486
MAHRTHID+SIKL+GK+LFGIEKGP++LK ++P G+PLV DW CLKSLVRTFETHCGSLS
Sbjct: 58 MAHRTHIDNSIKLIGKLLFGIEKGPEVLKGVQPAGEPLVYDWSCLKSLVRTFETHCGSLS 117
Query: 485 QYGMKHMRSIANICNAGIKQEQMAEASGQACVSFPSSSWSSLHMGFSA 342
QYGMKHMRSIANICNAG+ +EQM EAS QAC + PS+SWSSLH GFSA
Sbjct: 118 QYGMKHMRSIANICNAGVTKEQMTEASAQACTTLPSNSWSSLHRGFSA 165
>gb|KHN29737.1| Vacuolar-processing enzyme [Glycine soja]
Length = 483
Score = 189 bits (481), Expect = 9e-46
Identities = 84/108 (77%), Positives = 98/108 (90%)
Frame = -1
Query: 665 MAHRTHIDSSIKLVGKILFGIEKGPDMLKNIRPTGQPLVDDWDCLKSLVRTFETHCGSLS 486
M+HR HID S+K +GK+LFGIEKGP++L ++RP GQPLVDDWDCLK+LVRTFETHCGSLS
Sbjct: 376 MSHRMHIDDSMKRIGKLLFGIEKGPELLSSVRPAGQPLVDDWDCLKTLVRTFETHCGSLS 435
Query: 485 QYGMKHMRSIANICNAGIKQEQMAEASGQACVSFPSSSWSSLHMGFSA 342
QYGMKHMRS AN CNAGI++EQMAEAS QACV+ P+SSWSS+H GFSA
Sbjct: 436 QYGMKHMRSFANFCNAGIRKEQMAEASAQACVNIPASSWSSMHRGFSA 483
>ref|XP_009616670.1| PREDICTED: vacuolar-processing enzyme-like [Nicotiana
tomentosiformis] gi|27544008|dbj|BAC54828.1| vacuolar
processing enzyme-1b [Nicotiana tabacum]
Length = 489
Score = 189 bits (479), Expect = 2e-45
Identities = 85/108 (78%), Positives = 97/108 (89%)
Frame = -1
Query: 665 MAHRTHIDSSIKLVGKILFGIEKGPDMLKNIRPTGQPLVDDWDCLKSLVRTFETHCGSLS 486
++HR H+D+S+ LVGK+LFGIEKGP++L +RP GQPLVDDWDCLKS VRTFETHCGSLS
Sbjct: 382 ISHRVHLDNSVALVGKLLFGIEKGPEVLSGVRPAGQPLVDDWDCLKSFVRTFETHCGSLS 441
Query: 485 QYGMKHMRSIANICNAGIKQEQMAEASGQACVSFPSSSWSSLHMGFSA 342
QYGMKHMRSIANICNAGIK+EQM EAS QAC S PS++WSSLH GFSA
Sbjct: 442 QYGMKHMRSIANICNAGIKKEQMVEASAQACPSVPSNTWSSLHRGFSA 489
>ref|XP_009337146.1| PREDICTED: vacuolar-processing enzyme-like [Pyrus x bretschneideri]
Length = 495
Score = 188 bits (478), Expect = 2e-45
Identities = 84/108 (77%), Positives = 98/108 (90%)
Frame = -1
Query: 665 MAHRTHIDSSIKLVGKILFGIEKGPDMLKNIRPTGQPLVDDWDCLKSLVRTFETHCGSLS 486
M+HR HID ++KL+GK+LFGIEKGP++L +RP GQPLVDDWDCLK++VR+FETHCGSLS
Sbjct: 388 MSHRMHIDETMKLIGKLLFGIEKGPEVLNAVRPAGQPLVDDWDCLKTMVRSFETHCGSLS 447
Query: 485 QYGMKHMRSIANICNAGIKQEQMAEASGQACVSFPSSSWSSLHMGFSA 342
QYGMKHMRS+ANICNAG+ +EQMAEAS QACVS PS WSSLHMGFSA
Sbjct: 448 QYGMKHMRSLANICNAGMTKEQMAEASAQACVSVPSGRWSSLHMGFSA 495
>ref|XP_009361606.1| PREDICTED: vacuolar-processing enzyme-like [Pyrus x bretschneideri]
Length = 494
Score = 188 bits (477), Expect = 3e-45
Identities = 85/108 (78%), Positives = 97/108 (89%)
Frame = -1
Query: 665 MAHRTHIDSSIKLVGKILFGIEKGPDMLKNIRPTGQPLVDDWDCLKSLVRTFETHCGSLS 486
M+HR HID ++KL+GK+LFGIEKGP +L +RP GQPLVDDWDCLK++VR+FETHCGSLS
Sbjct: 387 MSHRMHIDQTMKLIGKLLFGIEKGPQVLNAVRPAGQPLVDDWDCLKTMVRSFETHCGSLS 446
Query: 485 QYGMKHMRSIANICNAGIKQEQMAEASGQACVSFPSSSWSSLHMGFSA 342
QYGMKHMRS+ANICNAG+ QEQMAEAS QACVS PSS WSSLH GFSA
Sbjct: 447 QYGMKHMRSLANICNAGMTQEQMAEASAQACVSAPSSRWSSLHRGFSA 494
>ref|XP_006578073.1| PREDICTED: vacuolar-processing enzyme-like [Glycine max]
Length = 483
Score = 188 bits (477), Expect = 3e-45
Identities = 83/108 (76%), Positives = 97/108 (89%)
Frame = -1
Query: 665 MAHRTHIDSSIKLVGKILFGIEKGPDMLKNIRPTGQPLVDDWDCLKSLVRTFETHCGSLS 486
M+HR HID S+K +GK+ FGIEKGP++L ++RP GQPLVDDWDCLK+LVRTFETHCGSLS
Sbjct: 376 MSHRMHIDDSMKRIGKLFFGIEKGPELLSSVRPAGQPLVDDWDCLKTLVRTFETHCGSLS 435
Query: 485 QYGMKHMRSIANICNAGIKQEQMAEASGQACVSFPSSSWSSLHMGFSA 342
QYGMKHMRS AN CNAGI++EQMAEAS QACV+ P+SSWSS+H GFSA
Sbjct: 436 QYGMKHMRSFANFCNAGIRKEQMAEASAQACVNIPASSWSSMHRGFSA 483
>dbj|BAC86022.1| unnamed protein product [Homo sapiens]
Length = 483
Score = 188 bits (477), Expect = 3e-45
Identities = 83/108 (76%), Positives = 97/108 (89%)
Frame = -1
Query: 665 MAHRTHIDSSIKLVGKILFGIEKGPDMLKNIRPTGQPLVDDWDCLKSLVRTFETHCGSLS 486
M+HR HID S+K +GK+ FGIEKGP++L ++RP GQPLVDDWDCLK+LVRTFETHCGSLS
Sbjct: 376 MSHRMHIDDSMKRIGKLFFGIEKGPELLSSVRPAGQPLVDDWDCLKTLVRTFETHCGSLS 435
Query: 485 QYGMKHMRSIANICNAGIKQEQMAEASGQACVSFPSSSWSSLHMGFSA 342
QYGMKHMRS AN CNAGI++EQMAEAS QACV+ P+SSWSS+H GFSA
Sbjct: 436 QYGMKHMRSFANFCNAGIRKEQMAEASAQACVNIPASSWSSMHRGFSA 483
>ref|XP_008393660.1| PREDICTED: vacuolar-processing enzyme [Malus domestica]
gi|658050486|ref|XP_008360960.1| PREDICTED:
vacuolar-processing enzyme-like [Malus domestica]
Length = 494
Score = 186 bits (473), Expect = 7e-45
Identities = 84/108 (77%), Positives = 96/108 (88%)
Frame = -1
Query: 665 MAHRTHIDSSIKLVGKILFGIEKGPDMLKNIRPTGQPLVDDWDCLKSLVRTFETHCGSLS 486
M+HR HID ++KL+GK+LFGIEKGP +L +RP GQPLVDDWDCLK++VR+FETHCGSLS
Sbjct: 387 MSHRMHIDQTMKLIGKLLFGIEKGPQVLNAVRPAGQPLVDDWDCLKTMVRSFETHCGSLS 446
Query: 485 QYGMKHMRSIANICNAGIKQEQMAEASGQACVSFPSSSWSSLHMGFSA 342
QYGMKHMRS+ANICNAG+ QEQMAEAS QACVS PS WSSLH GFSA
Sbjct: 447 QYGMKHMRSLANICNAGMTQEQMAEASAQACVSAPSGRWSSLHRGFSA 494
>ref|XP_002516472.1| Vacuolar-processing enzyme precursor, putative [Ricinus communis]
gi|223544292|gb|EEF45813.1| Vacuolar-processing enzyme
precursor, putative [Ricinus communis]
Length = 492
Score = 186 bits (473), Expect = 7e-45
Identities = 81/108 (75%), Positives = 96/108 (88%)
Frame = -1
Query: 665 MAHRTHIDSSIKLVGKILFGIEKGPDMLKNIRPTGQPLVDDWDCLKSLVRTFETHCGSLS 486
M+HR HID S+KL+GK+LFG+EK ++L +RP GQPLVDDWDCLK LVRTFETHCGS+S
Sbjct: 385 MSHRMHIDHSVKLIGKLLFGLEKASEVLSTVRPAGQPLVDDWDCLKKLVRTFETHCGSIS 444
Query: 485 QYGMKHMRSIANICNAGIKQEQMAEASGQACVSFPSSSWSSLHMGFSA 342
QYGMKHMRS+AN+CNAGI++EQMAEAS QAC++FPS WSSLH GFSA
Sbjct: 445 QYGMKHMRSLANLCNAGIREEQMAEASAQACITFPSGPWSSLHKGFSA 492
>gb|AGC94759.1| vacuolar processing enzyme [Malus micromalus]
Length = 494
Score = 186 bits (473), Expect = 7e-45
Identities = 84/108 (77%), Positives = 96/108 (88%)
Frame = -1
Query: 665 MAHRTHIDSSIKLVGKILFGIEKGPDMLKNIRPTGQPLVDDWDCLKSLVRTFETHCGSLS 486
M+HR HID ++KL+GK+LFGIEKGP +L +RP GQPLVDDWDCLK++VR+FETHCGSLS
Sbjct: 387 MSHRMHIDQTMKLIGKLLFGIEKGPQVLNAVRPAGQPLVDDWDCLKTMVRSFETHCGSLS 446
Query: 485 QYGMKHMRSIANICNAGIKQEQMAEASGQACVSFPSSSWSSLHMGFSA 342
QYGMKHMRS+ANICNAG+ QEQMAEAS QACVS PS WSSLH GFSA
Sbjct: 447 QYGMKHMRSLANICNAGMTQEQMAEASAQACVSAPSGRWSSLHRGFSA 494
>gb|AGC94758.1| vacuolar processing enzyme [Malus hupehensis]
Length = 494
Score = 186 bits (473), Expect = 7e-45
Identities = 84/108 (77%), Positives = 96/108 (88%)
Frame = -1
Query: 665 MAHRTHIDSSIKLVGKILFGIEKGPDMLKNIRPTGQPLVDDWDCLKSLVRTFETHCGSLS 486
M+HR HID ++KL+GK+LFGIEKGP +L +RP GQPLVDDWDCLK++VR+FETHCGSLS
Sbjct: 387 MSHRMHIDQTMKLIGKLLFGIEKGPQVLNAVRPAGQPLVDDWDCLKTMVRSFETHCGSLS 446
Query: 485 QYGMKHMRSIANICNAGIKQEQMAEASGQACVSFPSSSWSSLHMGFSA 342
QYGMKHMRS+ANICNAG+ QEQMAEAS QACVS PS WSSLH GFSA
Sbjct: 447 QYGMKHMRSLANICNAGMTQEQMAEASAQACVSAPSGRWSSLHRGFSA 494
>gb|AGC94756.1| vacuolar processing enzyme [Malus sieversii]
Length = 494
Score = 186 bits (473), Expect = 7e-45
Identities = 84/108 (77%), Positives = 96/108 (88%)
Frame = -1
Query: 665 MAHRTHIDSSIKLVGKILFGIEKGPDMLKNIRPTGQPLVDDWDCLKSLVRTFETHCGSLS 486
M+HR HID ++KL+GK+LFGIEKGP +L +RP GQPLVDDWDCLK++VR+FETHCGSLS
Sbjct: 387 MSHRMHIDQTMKLIGKLLFGIEKGPQVLNAVRPAGQPLVDDWDCLKTMVRSFETHCGSLS 446
Query: 485 QYGMKHMRSIANICNAGIKQEQMAEASGQACVSFPSSSWSSLHMGFSA 342
QYGMKHMRS+ANICNAG+ QEQMAEAS QACVS PS WSSLH GFSA
Sbjct: 447 QYGMKHMRSLANICNAGMTQEQMAEASAQACVSAPSGRWSSLHRGFSA 494
>gb|ACR24644.1| vacuolar processing enzyme [Malus hupehensis var. mengshanensis]
Length = 494
Score = 186 bits (473), Expect = 7e-45
Identities = 84/108 (77%), Positives = 96/108 (88%)
Frame = -1
Query: 665 MAHRTHIDSSIKLVGKILFGIEKGPDMLKNIRPTGQPLVDDWDCLKSLVRTFETHCGSLS 486
M+HR HID ++KL+GK+LFGIEKGP +L +RP GQPLVDDWDCLK++VR+FETHCGSLS
Sbjct: 387 MSHRMHIDQTMKLIGKLLFGIEKGPQVLNAVRPAGQPLVDDWDCLKTMVRSFETHCGSLS 446
Query: 485 QYGMKHMRSIANICNAGIKQEQMAEASGQACVSFPSSSWSSLHMGFSA 342
QYGMKHMRS+ANICNAG+ QEQMAEAS QACVS PS WSSLH GFSA
Sbjct: 447 QYGMKHMRSLANICNAGMTQEQMAEASAQACVSAPSGRWSSLHRGFSA 494
>ref|XP_011019533.1| PREDICTED: vacuolar-processing enzyme isoform X2 [Populus
euphratica]
Length = 395
Score = 186 bits (472), Expect = 1e-44
Identities = 85/108 (78%), Positives = 96/108 (88%)
Frame = -1
Query: 665 MAHRTHIDSSIKLVGKILFGIEKGPDMLKNIRPTGQPLVDDWDCLKSLVRTFETHCGSLS 486
M+HR HID SIKL+GK+LFGIEK ++L +RP GQPLVDDW CLK+LVRTFETHCGS+S
Sbjct: 288 MSHRMHIDHSIKLIGKLLFGIEKASEVLNTVRPAGQPLVDDWVCLKTLVRTFETHCGSIS 347
Query: 485 QYGMKHMRSIANICNAGIKQEQMAEASGQACVSFPSSSWSSLHMGFSA 342
QYGMKHMRS+AN+CNAGI +EQMAEAS QACVSFPS SWSSLH GFSA
Sbjct: 348 QYGMKHMRSLANLCNAGIVKEQMAEASAQACVSFPSGSWSSLHKGFSA 395
>ref|XP_011019532.1| PREDICTED: vacuolar-processing enzyme isoform X1 [Populus
euphratica]
Length = 493
Score = 186 bits (472), Expect = 1e-44
Identities = 85/108 (78%), Positives = 96/108 (88%)
Frame = -1
Query: 665 MAHRTHIDSSIKLVGKILFGIEKGPDMLKNIRPTGQPLVDDWDCLKSLVRTFETHCGSLS 486
M+HR HID SIKL+GK+LFGIEK ++L +RP GQPLVDDW CLK+LVRTFETHCGS+S
Sbjct: 386 MSHRMHIDHSIKLIGKLLFGIEKASEVLNTVRPAGQPLVDDWVCLKTLVRTFETHCGSIS 445
Query: 485 QYGMKHMRSIANICNAGIKQEQMAEASGQACVSFPSSSWSSLHMGFSA 342
QYGMKHMRS+AN+CNAGI +EQMAEAS QACVSFPS SWSSLH GFSA
Sbjct: 446 QYGMKHMRSLANLCNAGIVKEQMAEASAQACVSFPSGSWSSLHKGFSA 493
>gb|ACQ91103.1| vacuolar processing enzyme a [Populus tomentosa]
Length = 493
Score = 186 bits (472), Expect = 1e-44
Identities = 85/108 (78%), Positives = 96/108 (88%)
Frame = -1
Query: 665 MAHRTHIDSSIKLVGKILFGIEKGPDMLKNIRPTGQPLVDDWDCLKSLVRTFETHCGSLS 486
M+HR HID SIKL+GK+LFGIEK ++L N+RP GQPLVDDW CLK+LVRTFETHCGS+S
Sbjct: 386 MSHRMHIDHSIKLIGKLLFGIEKASEVLNNVRPAGQPLVDDWVCLKTLVRTFETHCGSIS 445
Query: 485 QYGMKHMRSIANICNAGIKQEQMAEASGQACVSFPSSSWSSLHMGFSA 342
QYGMKHMRS+AN+CNAGI +EQMAEAS QACVS PS SWSSLH GFSA
Sbjct: 446 QYGMKHMRSLANLCNAGIVKEQMAEASAQACVSIPSGSWSSLHKGFSA 493