BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Forsythia21_contig00001841
         (3361 letters)

Database: ./nr 
           69,698,275 sequences; 24,982,196,650 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_011093631.1| PREDICTED: DNA topoisomerase 1-like [Sesamum...  1243   0.0  
emb|CDP13767.1| unnamed protein product [Coffea canephora]           1182   0.0  
dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]                1175   0.0  
dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]      1163   0.0  
gb|EYU30724.1| hypothetical protein MIMGU_mgv1a001121mg [Erythra...  1156   0.0  
dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]              1155   0.0  
dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]               1150   0.0  
dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]            1142   0.0  
dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. g...  1140   0.0  
dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]            1134   0.0  
dbj|BAK32956.1| topoisomerase I [Ophiorrhiza fucosa]                 1125   0.0  
dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]                 1125   0.0  
dbj|BAK32961.1| topoisomerase I [Ophiorrhiza ridleyana]              1121   0.0  
dbj|BAK32959.1| topoisomerase I [Ophiorrhiza plumbea]                1110   0.0  
dbj|BAK32963.1| topoisomerase I [Ophiorrhiza sp. 35]                 1109   0.0  
dbj|BAK32957.1| topoisomerase I [Ophiorrhiza harrisiana]             1100   0.0  
ref|XP_007020664.1| DNA topoisomerase I alpha isoform 1 [Theobro...  1082   0.0  
ref|XP_009790344.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...  1075   0.0  
ref|XP_010266803.1| PREDICTED: DNA topoisomerase 1-like [Nelumbo...  1071   0.0  
ref|XP_009619726.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...  1070   0.0  

>ref|XP_011093631.1| PREDICTED: DNA topoisomerase 1-like [Sesamum indicum]
          Length = 893

 Score = 1243 bits (3217), Expect = 0.0
 Identities = 646/898 (71%), Positives = 707/898 (78%), Gaps = 3/898 (0%)
 Frame = -3

Query: 2993 MAVEACSXXXXXXXXXXXXXXLVFKRXXXXXXXXXXXXXXXXXXXXQKHDRQLGRPMPDV 2814
            MA+E+C+              LVFKR                     KHDR L RP PDV
Sbjct: 1    MAIESCNDQKLMDDMDEDDEPLVFKRSSSSAKQSQGNSETKRPLSQ-KHDRPLNRPSPDV 59

Query: 2813 RSQNGKSSVVQKGKMAFSSKSPPVKSPLRSPEASNSSAKAYPLRPPEANLRPSAAY--RS 2640
            R QNG+S+++QK K   SS++PP++SPL SP++SNSSAKA  +RP E + RPS +    S
Sbjct: 60   RPQNGQSTMIQKSKTVPSSRTPPLRSPLASPKSSNSSAKALAVRPREVDPRPSTSVTDES 119

Query: 2639 DNVNRPMKVGKPSIGSATEPN-DSDDSEDDKPLSARLSTGLXXXXXXXXXXXXXXSRLGQ 2463
            ++V   +K  KPS  +    N DS+DSEDDKPLSARL  GL                  Q
Sbjct: 120  NSVKHQIKDEKPSTKATGGLNEDSEDSEDDKPLSARLPAGLSKVNSNHANKGPNALTSVQ 179

Query: 2462 KPSIPKLEDSDDEKPLSSKVQLKSNVGTSYASKSYDSDEDKPLVAKNNQNGSALRDSSSK 2283
            K  IPK EDSDDE PLSSK Q+KSN G S    S  S E KPL+AK +QNGSA   S+ +
Sbjct: 180  KTKIPKPEDSDDEIPLSSKFQVKSNAGESTNRPSI-SGERKPLLAKYDQNGSA---SAER 235

Query: 2282 KPSTMLSKRPASEIKSAGQSSVKKHKLSNASVPINNKQASVKAEPKVEDDDDHVPISQRM 2103
            KPST+L KRPA  +KSAG+S +KK KLS+AS P   K+ S+K E K EDD+DHVPISQR+
Sbjct: 236  KPSTILKKRPADGVKSAGESYLKKPKLSDASTPNKTKETSIKDEMKDEDDEDHVPISQRI 295

Query: 2102 KKPATADKKSSAVKNVTXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPPGSGEGQKWTTLI 1923
            K+  ++DKKSS+ KN+T                            VPP SGEGQKWTTL+
Sbjct: 296  KQQTSSDKKSSSAKNMTKPISASAKKTSKKPKKVMKNSKYSKSSKVPPSSGEGQKWTTLV 355

Query: 1922 HNGVIFPPPYQPHGVKILYKGKPVNLTPEQEEVATMFAVMLDTEYMSKPKFKENFMSDWR 1743
            HNGVIFPPPY+PHGVK+LYKGKPV+LTPEQEEVATM+AVMLDT+YM+KPKFKENFM+DWR
Sbjct: 356  HNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLDTDYMNKPKFKENFMADWR 415

Query: 1742 KILGKNHIIQNLEDCDFTPIYEWHQXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAIVNG 1563
            KILGKNH+IQ+LE CDFTPIYEWHQ                          KYMWAIVNG
Sbjct: 416  KILGKNHVIQSLEHCDFTPIYEWHQKEKEKKKQMTAEEKKALKEEKLKQEEKYMWAIVNG 475

Query: 1562 VKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAPIPECPIPGERWKEI 1383
            VKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRPSDITINIGKDAPIPECPIPGE WKEI
Sbjct: 476  VKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWKEI 535

Query: 1382 RHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKSRLLKDYIQGIRAAYTK 1203
            RHDNTVTWLA+WNDPINPKEFKYVFLAASSTLKGQSDKEKYEK+RLLKDYI GIRAAYTK
Sbjct: 536  RHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTK 595

Query: 1202 DFASKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPIPPNILKFDF 1023
            DF +KD TKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP+PPNILKFDF
Sbjct: 596  DFTNKDPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDF 655

Query: 1022 LGKDSIRYQNEVEVEPAVFKAIQQFRSGKKAGDDIFDKLDTSKLNAHLKELMPGLTAKVF 843
            LGKDSIRYQNEVEVE  VFKAIQQFRSGKK  DD+FD+LDTSKLNAHLKELMPGLTAKVF
Sbjct: 656  LGKDSIRYQNEVEVETPVFKAIQQFRSGKKGSDDMFDRLDTSKLNAHLKELMPGLTAKVF 715

Query: 842  RTYNASITLDEMLSRETKGGDVAENVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEK 663
            RTYNASITLD+ LSRETKGGDVAE VVVYQHANKEVAIICNHQRTVSKSHSAQM RLNEK
Sbjct: 716  RTYNASITLDDKLSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMTRLNEK 775

Query: 662  IEELKGVLEELTTDLSRAKKGKPPLKSADGKPKRNLNPEALEKKISQTNAKIEKMERDKE 483
            IEELKGVLEEL TDL+RAKKGKPPLKSADGKPKRNLNP+ALEKKI+QTNAKIEKMERDKE
Sbjct: 776  IEELKGVLEELQTDLARAKKGKPPLKSADGKPKRNLNPDALEKKIAQTNAKIEKMERDKE 835

Query: 482  TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPSFRF 309
            TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF WAMDVDPSFRF
Sbjct: 836  TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPSFRF 893


>emb|CDP13767.1| unnamed protein product [Coffea canephora]
          Length = 926

 Score = 1182 bits (3057), Expect = 0.0
 Identities = 627/928 (67%), Positives = 691/928 (74%), Gaps = 33/928 (3%)
 Frame = -3

Query: 2993 MAVEACSXXXXXXXXXXXXXXLVFKRXXXXXXXXXXXXXXXXXXXXQKHDRQLGRPMPDV 2814
            MAVEACS              LVFKR                     K D Q  R   DV
Sbjct: 1    MAVEACSTPSLLEDSDEENAPLVFKRTSSSSKQNLSNSETKKLSSQ-KRDGQSSRNSSDV 59

Query: 2813 RSQNGKSSVVQKGKMAFSSKSPPVKSPLRSPEASNSSAKAYPLRPPEANLRPSAAYRS-- 2640
               NG+SS  Q G++  S+K+PP KSPL SP+A+N SAK   +  P AN +PS++  +  
Sbjct: 60   CPVNGQSSSAQTGRVVSSAKTPPAKSPLSSPKAANISAKTSLITSPGANSKPSSSTSATV 119

Query: 2639 ----DNVNRPM-KVGKPSIGSATEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXXXS 2475
                ++ N P+ K+ K S+ +A   +  +DS+DDKPL A+L +G               S
Sbjct: 120  KQLENHKNSPVVKLPKRSVSAAKLSSTPEDSDDDKPLMAKLPSGSSRAIVNHGNKDGDGS 179

Query: 2474 RLGQKPSIPKLEDSDDEKPLSSKVQLKSNVGTSYASKSYDSDEDKPLVAKNNQNGSALRD 2295
             L QKP + + EDSDDEKPLSS+   KSN+  S  SKS +  E K L AK  QNGSALRD
Sbjct: 180  SLVQKPGVEEDEDSDDEKPLSSRYLSKSNLVESI-SKSRNPGEKKSLPAKVQQNGSALRD 238

Query: 2294 SSSKKPSTMLSKRPASEIKSAGQSSVKKHKLSNASVPINNKQASVKAEPKVEDDDD---- 2127
                K S++ +KRP  E+KS+ +S+VKK KLS  +  IN KQA++KAEPKVEDDDD    
Sbjct: 239  GPVGKSSSLSNKRPPGEVKSSDESAVKKPKLSGPTAAINKKQATLKAEPKVEDDDDDILI 298

Query: 2126 ----------------------HVPISQRMKKPATADKKSSAVKNVTXXXXXXXXXXXXX 2013
                                  HVPI+QRMKK  T+  +SS+VK V              
Sbjct: 299  SQTAKKMFASASKPKSNDDDDDHVPITQRMKKSTTSVSQSSSVKKVAKVVSSSLKKTNKK 358

Query: 2012 XXXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQ 1833
                           VPPGSGEGQKWTTL+HNGVIFPPPY+PHGVK+LYKG+PV LTPEQ
Sbjct: 359  SKKIIKKSKYSKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGQPVTLTPEQ 418

Query: 1832 EEVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFTPIYEWHQXXXXX 1653
            EEVATMFAVMLDT+YMSKP+FKENF SDW++ILGKNH IQNLEDCDF PIYEWHQ     
Sbjct: 419  EEVATMFAVMLDTDYMSKPQFKENFFSDWKRILGKNHTIQNLEDCDFRPIYEWHQKEKEK 478

Query: 1652 XXXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKR 1473
                                 KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+
Sbjct: 479  KKQMTTEEKKSLKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKK 538

Query: 1472 RIRPSDITINIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASS 1293
            RIRP DITINIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASS
Sbjct: 539  RIRPRDITINIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASS 598

Query: 1292 TLKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFASKDLTKKQIAVATYLIDKLALRAGNEK 1113
            TLKGQSDKEKYEK+RLLKDYI GIR AYTKDFASKD  KKQIAVATYLIDKLALRAGNEK
Sbjct: 599  TLKGQSDKEKYEKARLLKDYIHGIRTAYTKDFASKDPMKKQIAVATYLIDKLALRAGNEK 658

Query: 1112 DDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKK 933
            DDDEADTVGCCTLKVENVEP+PPNILKFDFLGKDSIRYQNEVEVE  VFKAIQQFRSGK+
Sbjct: 659  DDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVESGVFKAIQQFRSGKE 718

Query: 932  AGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQ 753
              +D+FDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLSR+T GGDV E VVVYQ
Sbjct: 719  GSEDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRKTNGGDVLEKVVVYQ 778

Query: 752  HANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADG 573
             ANKEVAIICNHQRTVSK+HSAQM RLNEKIEELKGVLEEL TDLSRAKKGKPPLK+ADG
Sbjct: 779  QANKEVAIICNHQRTVSKTHSAQMSRLNEKIEELKGVLEELKTDLSRAKKGKPPLKNADG 838

Query: 572  KPKRNLNPEALEKKISQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH 393
            KPKRNLNPEALE+KI+QTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH
Sbjct: 839  KPKRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH 898

Query: 392  EVPIEKIFNKSLLAKFTWAMDVDPSFRF 309
            EVPIEKIFNKSLLAKF W+MDVDPSFRF
Sbjct: 899  EVPIEKIFNKSLLAKFAWSMDVDPSFRF 926


>dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]
          Length = 910

 Score = 1175 bits (3039), Expect = 0.0
 Identities = 628/922 (68%), Positives = 688/922 (74%), Gaps = 27/922 (2%)
 Frame = -3

Query: 2993 MAVEACSXXXXXXXXXXXXXXLVFKRXXXXXXXXXXXXXXXXXXXXQKHDRQLGRPMPDV 2814
            MAVEAC               +VFKR                     K D Q  R + D 
Sbjct: 1    MAVEACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRKVSSQ-KRDGQSVRQIYDS 59

Query: 2813 RSQNGKSSVVQKGKMAFSSK---------SPP-----VKSPLRSPEASNSSAKAYPLRPP 2676
            R  NG+SS  QKG+M   SK         SPP     VKSPL SP+ S SSAK  P+   
Sbjct: 60   RPANGESSSGQKGRMVPPSKPSQVKSPLSSPPSKPSQVKSPLSSPKVSTSSAKKSPVSSL 119

Query: 2675 EANLRPSAA----------YRSDNVNRPMKVGKPSIGSATEPNDSDDSEDDKPLSARLST 2526
             AN +PS +          ++S  V +  K     + SA   NDS+DS+D KPLS R S 
Sbjct: 120  PANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAII-NDSEDSDDGKPLSLRHSA 178

Query: 2525 GLXXXXXXXXXXXXXXSRLGQKPSIPKLEDSDDEKPLSSKVQLKSNVGTSYASKSYDSDE 2346
                            +++ ++ S P+ EDSDDEKPLSS+  LKS VG S  SK+YDSD+
Sbjct: 179  S---------SSKGNTNQVSKEGSKPENEDSDDEKPLSSRFPLKSGVGES-TSKAYDSDD 228

Query: 2345 DKPLVAKNNQNGSALRDSSSKKPSTMLSKRPASEIKSAGQSSVKKHKLSNASVPINNKQA 2166
            DKPL  K   NGSA+RD    K S M +KRP  +IKS+ Q SVKK KLS+ + P N KQA
Sbjct: 229  DKPLAKKLQHNGSAMRDGQPNKYSNMSNKRPPGDIKSSNQLSVKKPKLSSVTAPTNKKQA 288

Query: 2165 SVKAEPKVEDDDD-HVPISQRMKKPATADKKSSAVKNVTXXXXXXXXXXXXXXXXXXXXX 1989
            SVK EPK EDDDD H+PISQR+KK  T++ KSS++K  T                     
Sbjct: 289  SVKPEPKAEDDDDDHLPISQRIKKSPTSESKSSSIKKTTKVVSSSVKKVNKKSKKVMKNS 348

Query: 1988 XXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQEEVATMFA 1809
                   VPP SGEG+KW  L HNGVIFPPPY+PHG+K+LYKGKPV+LTPEQEEVATMFA
Sbjct: 349  KYSKSSKVPPSSGEGKKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVATMFA 408

Query: 1808 VMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFTPIYEWHQXXXXXXXXXXXXX 1629
            VMLDT+YM+KP+FKENF  DW+KILGKNH+IQNLE+CDF+PIYEWHQ             
Sbjct: 409  VMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSEKEKKKQMTTEE 468

Query: 1628 XXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDIT 1449
                         KYMWA V+G KEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRP DIT
Sbjct: 469  KKALKEEKLKQEEKYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCDIT 528

Query: 1448 INIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGQSDK 1269
            INIGKDAPIPECP+PGERWKE+RHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKG SDK
Sbjct: 529  INIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGLSDK 588

Query: 1268 EKYEKSRLLKDYIQGIRAAYTKDFASKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTV 1089
            EKYEK+RLLKDYIQGIRAAYTKDFASKD TKKQIAVATYLIDKLALRAGNEKDDDEADTV
Sbjct: 589  EKYEKARLLKDYIQGIRAAYTKDFASKDPTKKQIAVATYLIDKLALRAGNEKDDDEADTV 648

Query: 1088 GCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKKAGDDIFDK 909
            GCCTLKVENVEP+PPNILKFDFLGKDSIRYQNEVEVE AVFKAIQQFRSGK+   D+FD 
Sbjct: 649  GCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSSDLFDL 708

Query: 908  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQHANKEVAI 729
            LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLSRETKGGDVAE VVVYQHANKEVAI
Sbjct: 709  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKEVAI 768

Query: 728  ICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKS--ADGKPKRNL 555
            ICNHQRTVSKSHSAQMLRLNEKIEELK V+EEL +DLSR KKGKPPLKS  ADGKPKRNL
Sbjct: 769  ICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPKRNL 828

Query: 554  NPEALEKKISQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEK 375
            NPE+LEKKI+QTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEK
Sbjct: 829  NPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEK 888

Query: 374  IFNKSLLAKFTWAMDVDPSFRF 309
            IFNKSLLAKFTWAMDVDPSFRF
Sbjct: 889  IFNKSLLAKFTWAMDVDPSFRF 910


>dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]
          Length = 925

 Score = 1163 bits (3008), Expect = 0.0
 Identities = 609/881 (69%), Positives = 675/881 (76%), Gaps = 33/881 (3%)
 Frame = -3

Query: 2852 KHDRQLGRPMPDVRSQNGKSSVVQKGKMAFSSKSPPVKSPLRSPEASNSSAKAYPLRPPE 2673
            K D Q      DVR  NG+SS  QKG++  S+K+PPVKSPL SP+ASNSSAKA P+  P 
Sbjct: 46   KQDGQSAVHTSDVRPANGESSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPG 105

Query: 2672 ANLRPSAAYRS----DNVNRPMKV---GKPSIGSATEPNDSDDSEDDKPLSARLSTGLXX 2514
            AN +PSA+  S     N ++        KPS+ +A   ++S+ S+D+KPLSAR       
Sbjct: 106  ANSKPSASATSTAKQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSK 165

Query: 2513 XXXXXXXXXXXXSRLGQKPSIPKLEDSDDEKPLSSKVQLKSNVGTSYASKSYDSDEDKPL 2334
                        S   ++P I + EDS+DEKPLS +   KS++G S  SKSYDSDE KPL
Sbjct: 166  GKSNHANKEGGDSCSIRRPVIEESEDSEDEKPLSCRFTSKSSLGES-TSKSYDSDEKKPL 224

Query: 2333 VAKNNQNGSALRDSSSKKPSTMLSKRPASEIKSAGQSSVKKHKLSNASVPINNKQASVKA 2154
             AK  QNGSA RD    K +++ +KRP  E KS  QSSVKK KLS+    I+NKQA+VK 
Sbjct: 225  AAKVQQNGSASRDGPMNKSASLSNKRPPGEAKSLNQSSVKKPKLSSPITSISNKQAAVKP 284

Query: 2153 EPKVEDDDDHVPISQRMKK-------------------------PATADKKSSAVKNVTX 2049
            EPK EDDDD++P+SQR KK                         PA+  K S  VK  + 
Sbjct: 285  EPKAEDDDDNIPLSQRGKKSQSATSKPKDDDDDNVPISQRIKKSPASVSKSSVPVKKAST 344

Query: 2048 XXXXXXXXXXXXXXXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKIL 1869
                                       VPPGSGEGQKWTTL+HNGVIFPPPY+PHGVK+L
Sbjct: 345  VVSSSLKKVNKNSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKML 404

Query: 1868 YKGKPVNLTPEQEEVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFT 1689
            YK +P+ LTPEQEEVATMFAVMLDT+YM+KP FKENF SDW+KILGKNH+IQNLEDCDF 
Sbjct: 405  YKRQPITLTPEQEEVATMFAVMLDTDYMNKPCFKENFFSDWKKILGKNHMIQNLEDCDFG 464

Query: 1688 PIYEWHQXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRG 1509
            PIYEWHQ                          KYMWAIV+GVKEKVGNFRVEPPGLFRG
Sbjct: 465  PIYEWHQQEKEKKKQMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRG 524

Query: 1508 RGEHPKMGKLKRRIRPSDITINIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINP 1329
            RGEHPKMGKLK+RIRP DITINIGKDAPIPECPIPGERWKE+R+ NTVTWLA+WNDPIN 
Sbjct: 525  RGEHPKMGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNGNTVTWLAYWNDPINQ 584

Query: 1328 KEFKYVFLAASSTLKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATY 1152
            KEFKYVFLAASSTLKGQSDKEKYEK+RLLKDYI GIRAAYTKDF + KD  KKQIAVATY
Sbjct: 585  KEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATY 644

Query: 1151 LIDKLALRAGNEKDDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPA 972
            LIDKLALRAGNEKDDDEADTVGCCTLKVENVEP+PPNILKFDFLGKDSIRYQNEV+VEPA
Sbjct: 645  LIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPA 704

Query: 971  VFKAIQQFRSGKKAGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRET 792
            VFKAIQQFRSGK+  +D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS+ET
Sbjct: 705  VFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKET 764

Query: 791  KGGDVAENVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSR 612
            KGG+VAENVVVYQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  LEEL TDLSR
Sbjct: 765  KGGEVAENVVVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSR 824

Query: 611  AKKGKPPLKSADGKPKRNLNPEALEKKISQTNAKIEKMERDKETKEDLKTVALGTSKINY 432
            AKKGKPP K ADGK KRNLNPEALE+KI+QTNAKIEKMERDKETKEDLKTVALGTSKINY
Sbjct: 825  AKKGKPPTKGADGKAKRNLNPEALERKITQTNAKIEKMERDKETKEDLKTVALGTSKINY 884

Query: 431  LDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPSFRF 309
            LDPRITVAWCKRHEVPIEKIFNKSLLAKF W+MDVDPSFRF
Sbjct: 885  LDPRITVAWCKRHEVPIEKIFNKSLLAKFAWSMDVDPSFRF 925


>gb|EYU30724.1| hypothetical protein MIMGU_mgv1a001121mg [Erythranthe guttata]
          Length = 883

 Score = 1156 bits (2990), Expect = 0.0
 Identities = 598/852 (70%), Positives = 674/852 (79%), Gaps = 4/852 (0%)
 Frame = -3

Query: 2852 KHDRQLGRPMPDVRSQNGKSSVVQKGKMAFSSKS--PPVKSPLRSPEASNSSAKAYPLRP 2679
            KH+ Q+GR   DVR QNG ++  QKGK   SS S  PPV+  L SP++SNSS KA P++ 
Sbjct: 47   KHNAQVGRQSSDVRPQNGTNANAQKGKSVTSSSSMKPPVRPSLVSPKSSNSSVKASPIKS 106

Query: 2678 PEANLRPSAAYRSDNVNRPMKVGKPSIGSATEPNDSDDSEDDKPLSARLSTGLXXXXXXX 2499
            P+ N +PS +   ++          S+ S  +  +S+DSEDDKPLSAR   G        
Sbjct: 107  PDVNSKPSTSVVGES---------KSVKSTIKEENSEDSEDDKPLSARQVAG-SSKNNPN 156

Query: 2498 XXXXXXXSRLGQKPSIPKLEDSDDEKPLSSKVQLKSNVGTSYASKSYDSDEDKPLVA-KN 2322
                     LG+K ++PK EDSDDE PLS+K Q KSN G S  S+S  S+E KPLVA K 
Sbjct: 157  QTNKPNAPNLGKKSNVPKPEDSDDEIPLSAKFQGKSNAGAS-TSRSSHSEEKKPLVARKP 215

Query: 2321 NQNGSALRDSSSKKPSTMLSKRPASEIKSAGQSSVKKHKLSNASVPINNKQASVKAEPKV 2142
            ++NGSA   S+ +KPST+L KRPA  + SAGQS++KK KLS+ S+   +K+ASVK E K 
Sbjct: 216  DKNGSA---STERKPSTVLQKRPADGVASAGQSNLKKPKLSD-SLASKDKKASVKPEVKA 271

Query: 2141 EDDDDHVPISQRMKKPATADKKSS-AVKNVTXXXXXXXXXXXXXXXXXXXXXXXXXXXXV 1965
            EDD+D VP+SQR KK  T +KK S A+K                               +
Sbjct: 272  EDDEDLVPLSQRTKKSTTPEKKPSPALKTNNKTNSKTNSKTNKKSKQVSKDNNYSKSSKL 331

Query: 1964 PPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQEEVATMFAVMLDTEYM 1785
            PP SG+GQKWTTL+HNGVIFPPPY+PHGVK+LYKGKPVNLTPEQEEVATM+AVML+T+Y+
Sbjct: 332  PPSSGDGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVNLTPEQEEVATMYAVMLETDYL 391

Query: 1784 SKPKFKENFMSDWRKILGKNHIIQNLEDCDFTPIYEWHQXXXXXXXXXXXXXXXXXXXXX 1605
             KP+FKENFM+DW+KILGKNH+IQ+LE CDFTPIYEWHQ                     
Sbjct: 392  KKPQFKENFMTDWKKILGKNHVIQSLEHCDFTPIYEWHQREKEKKKQMSTDEKKALKEEK 451

Query: 1604 XXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAP 1425
                 KYMWA+++GV+EKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIG+DAP
Sbjct: 452  LKLEEKYMWAVLDGVREKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGRDAP 511

Query: 1424 IPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKSRL 1245
            IPECPI GERWKEIRHDNTVTWLA+W+DPIN KEFKYVFLAASSTLKGQSDKEKYEK+RL
Sbjct: 512  IPECPIEGERWKEIRHDNTVTWLAYWSDPINGKEFKYVFLAASSTLKGQSDKEKYEKARL 571

Query: 1244 LKDYIQGIRAAYTKDFASKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE 1065
            LKDYIQGIR AYT+DF SKD  KKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE
Sbjct: 572  LKDYIQGIRTAYTRDFVSKDPAKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE 631

Query: 1064 NVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKKAGDDIFDKLDTSKLNA 885
            NVEP+PPNILKFDFLGKDSIRYQNEVEVE AVFKAIQQFRSGKK GDD+FDKLDTSKLNA
Sbjct: 632  NVEPVPPNILKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDKLDTSKLNA 691

Query: 884  HLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQHANKEVAIICNHQRTV 705
            HLKELMPGLTAKVFRTYNASITLD+ LSRETKGGD+AE VV Y HANKEVAIICNHQRTV
Sbjct: 692  HLKELMPGLTAKVFRTYNASITLDDKLSRETKGGDLAEKVVTYNHANKEVAIICNHQRTV 751

Query: 704  SKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADGKPKRNLNPEALEKKIS 525
            SK+HSAQMLRL+EKI+ELKGVLEEL TDL RA+KGKP L  ADGK KRN+NPEALE+KI+
Sbjct: 752  SKTHSAQMLRLDEKIDELKGVLEELKTDLGRARKGKPLLAGADGKAKRNINPEALERKIA 811

Query: 524  QTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 345
            QT AKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEK+FNKSLL KF
Sbjct: 812  QTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKMFNKSLLEKF 871

Query: 344  TWAMDVDPSFRF 309
            +WAMDVDPSFRF
Sbjct: 872  SWAMDVDPSFRF 883


>dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]
          Length = 894

 Score = 1155 bits (2987), Expect = 0.0
 Identities = 608/860 (70%), Positives = 674/860 (78%), Gaps = 12/860 (1%)
 Frame = -3

Query: 2852 KHDRQLGRPMPDVRSQNGKSSVVQKGKMAFSSKSPPVKSPLRSPEASNSSAKAYPLRPPE 2673
            ++D Q GR + DV S NG+SS   KGK   ++K   +KSP+ SP+AS S AKA P+  P+
Sbjct: 46   RYDGQSGRQVSDVPSTNGQSSSASKGK---TTKLSSMKSPIASPKASTSFAKASPVANPK 102

Query: 2672 ANL----RPSAAYRSDNVNRPMKVGKPSIGSATEPNDSDDSEDDKPLSARLSTGLXXXXX 2505
             +     R   + + + +N  +K  K  +  A EP    DSED+KPLSARL TGL     
Sbjct: 103  VSSSSDDRSKHSSKQNTIN-VVKEEKELVNPAAEPYG--DSEDEKPLSARLFTGLTKGSS 159

Query: 2504 XXXXXXXXXSRLGQKPSIPKLE------DSDDEKPLSSKVQLKSNVGTSYASKSYDSDED 2343
                     S     P +PK E      DSDDE PLSSK +LK+N GTS   KSY+SD++
Sbjct: 160  NNANKGLINSSPASLP-VPKPEINRYSDDSDDEIPLSSKFRLKANAGTSTV-KSYESDDN 217

Query: 2342 KPLVAKNNQNGSALRDSSSKKPSTMLSKRPASEIKSAGQSSVKKHKLSNASVPINNKQAS 2163
            K LV+   QNGS  R S S   S  ++KRP  E+KS+ QSSVKK KLS+AS P+NNKQAS
Sbjct: 218  KTLVSNFQQNGSINRGSKS---SIKVNKRPLGEVKSSVQSSVKKPKLSDASTPVNNKQAS 274

Query: 2162 VKAEPKVED-DDDHVPISQRMKKPATADKKSSAVKN-VTXXXXXXXXXXXXXXXXXXXXX 1989
             KAEPK +D DDDHVPISQRMKK AT+  KSS  K  VT                     
Sbjct: 275  KKAEPKADDSDDDHVPISQRMKKSATSGNKSSTAKQKVTKVVSSSMKKASKKFKKVVKKS 334

Query: 1988 XXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQEEVATMFA 1809
                   VPP SGEG+KW TL+HNGVIFPPPY+PHGVK+LYKGKPV+LTPEQEEVATMFA
Sbjct: 335  KYSKSSKVPPSSGEGKKWNTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFA 394

Query: 1808 VMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFTPIYEWHQXXXXXXXXXXXXX 1629
            VMLDT+YM+K KFKENFM DWRKILGKNH+IQNLEDCDFTPIYEWHQ             
Sbjct: 395  VMLDTDYMTKSKFKENFMDDWRKILGKNHVIQNLEDCDFTPIYEWHQREKEKKKKMTAEE 454

Query: 1628 XXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDIT 1449
                         KYMWAIVNGVKEKVGNFRVEPP LFRGRGEHPKMGKLK+ IRPSDIT
Sbjct: 455  KKVLKEERLKQEEKYMWAIVNGVKEKVGNFRVEPPSLFRGRGEHPKMGKLKKCIRPSDIT 514

Query: 1448 INIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGQSDK 1269
            INIGKDAPIPECPIPGE WKEIRHDNTVTWLAFWNDPI P+EFKYVFLAASS+LKGQSDK
Sbjct: 515  INIGKDAPIPECPIPGESWKEIRHDNTVTWLAFWNDPIKPREFKYVFLAASSSLKGQSDK 574

Query: 1268 EKYEKSRLLKDYIQGIRAAYTKDFASKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTV 1089
            EKYEK+RLLKD+IQGIRAAYTKDFASKD+TK+QIAVATYLIDKLALRAGNEKDDDEADTV
Sbjct: 575  EKYEKARLLKDFIQGIRAAYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTV 634

Query: 1088 GCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKKAGDDIFDK 909
            GCCTLKVENVEP PP+ILKFDFLGKDSIRYQNEVEVE  V+KAIQQFR+GK+ GDD+FDK
Sbjct: 635  GCCTLKVENVEPKPPSILKFDFLGKDSIRYQNEVEVELPVYKAIQQFRTGKRGGDDLFDK 694

Query: 908  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQHANKEVAI 729
            LDTSKLNAHLK LMPGLTAKVFRTYNASITLDEMLSRETKGG+VAE +VVYQHANKEVAI
Sbjct: 695  LDTSKLNAHLKGLMPGLTAKVFRTYNASITLDEMLSRETKGGNVAEKIVVYQHANKEVAI 754

Query: 728  ICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADGKPKRNLNP 549
            ICNHQRTVSKSH AQM RLN KI+ELKG+L+ L TDL+RAKKGKPPL+ ADGKPKRNL P
Sbjct: 755  ICNHQRTVSKSHPAQMTRLNGKIDELKGILDGLQTDLARAKKGKPPLEDADGKPKRNLTP 814

Query: 548  EALEKKISQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 369
            EALE+KI QTNAKIEKMERDKETKE LKT+ALGTSKI+YLDPRITVAWCKRHEVPIEK+F
Sbjct: 815  EALERKIGQTNAKIEKMERDKETKEGLKTIALGTSKISYLDPRITVAWCKRHEVPIEKVF 874

Query: 368  NKSLLAKFTWAMDVDPSFRF 309
            NKSLLAKF W+MDVDPSFRF
Sbjct: 875  NKSLLAKFAWSMDVDPSFRF 894


>dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]
          Length = 927

 Score = 1150 bits (2974), Expect = 0.0
 Identities = 603/883 (68%), Positives = 672/883 (76%), Gaps = 35/883 (3%)
 Frame = -3

Query: 2852 KHDRQLGRPMPDVRSQNGKSSVVQKGKMAFSSKSPPVKSPLRSPEASNSSAKAYPLRPPE 2673
            KH  Q      DVR  NG+SS  QKG++  S+K+PPVKSPL SP+ASNSSAKA P+  P 
Sbjct: 46   KHVGQSAVHTSDVRPANGESSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPG 105

Query: 2672 ANLRPSAAYRS----DNVNRPMKV---GKPSIGSATEPNDSDDSEDDKPLSARLSTGLXX 2514
            AN +PSA+  S     N ++        KPS+ +A   ++S+ S+D+KPLSAR       
Sbjct: 106  ANSKPSASATSTAKQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSK 165

Query: 2513 XXXXXXXXXXXXSRLGQKPSIPKLEDSDDEKPLSSKVQLKSNVGTSYASKSYDSDEDKPL 2334
                        S   ++  I + EDS+DEKPLS +   KS++G S  SKSYDSDE KPL
Sbjct: 166  GKSNHANKEGGDSCSIRRRVIEESEDSEDEKPLSRRFTSKSSLGES-TSKSYDSDEKKPL 224

Query: 2333 VAKNNQNGSALRDSSSKKPSTMLSKRPASEIKSAGQSSVKKHKLSNASVPINNKQASVKA 2154
             AK  QNGS  RD    K +++ +KRP  E+KS  QSSVKK KLS+    I+NKQA+VK 
Sbjct: 225  AAKVQQNGSVSRDGPMNKSASLSNKRPPGEVKSLNQSSVKKPKLSSPITSISNKQAAVKP 284

Query: 2153 EP--KVEDDDDHVPISQRMKK-------------------------PATADKKSSAVKNV 2055
            EP  K EDDDD++P+SQR KK                         PA+  K S+ VK  
Sbjct: 285  EPEPKAEDDDDNIPLSQRGKKSQAATSKPKDEDDDNVPIAQRIKKSPASVSKSSAPVKKA 344

Query: 2054 TXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVK 1875
            +                            VPPGSGEGQKWTTL+HNGVIFPPPY PHGVK
Sbjct: 345  STVVSPSLKKVNKNSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYNPHGVK 404

Query: 1874 ILYKGKPVNLTPEQEEVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCD 1695
            +LYK +P+ LTPEQEEVATMFAVMLDT+YM+KP+FKENF SDW+K+LGKNH IQNLEDCD
Sbjct: 405  MLYKRQPITLTPEQEEVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCD 464

Query: 1694 FTPIYEWHQXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLF 1515
            F PIYEWHQ                          KYMWAIV+GVKEKVGNFRVEPPGLF
Sbjct: 465  FGPIYEWHQQEKEKKKQMTTEEKKALKEDKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLF 524

Query: 1514 RGRGEHPKMGKLKRRIRPSDITINIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPI 1335
            RGRGEHPKMGKLK+RIRP DITINIGKDAPIPECPIPGERWKE+R+DNTVTWLAFW DPI
Sbjct: 525  RGRGEHPKMGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWIDPI 584

Query: 1334 NPKEFKYVFLAASSTLKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVA 1158
            N KEFKYVFLAASSTLKGQSDKEKYEK+RLLKDYI GIRAAYTKDF + KD  KKQIAVA
Sbjct: 585  NQKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVA 644

Query: 1157 TYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVE 978
            TYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP+PPNILKFDFLGKDSIRYQNEV+VE
Sbjct: 645  TYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVE 704

Query: 977  PAVFKAIQQFRSGKKAGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSR 798
            PAVFKAIQQFRSGK+  +D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS+
Sbjct: 705  PAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSK 764

Query: 797  ETKGGDVAENVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDL 618
            ETKGG+VAE VVVYQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL TDL
Sbjct: 765  ETKGGEVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTAMEELKTDL 824

Query: 617  SRAKKGKPPLKSADGKPKRNLNPEALEKKISQTNAKIEKMERDKETKEDLKTVALGTSKI 438
            SR KKGKPP K ADGKPKRNLNPEALE+K++Q NAKIEKMERDKETKEDLKTVALGTSKI
Sbjct: 825  SRVKKGKPPSKGADGKPKRNLNPEALERKMAQINAKIEKMERDKETKEDLKTVALGTSKI 884

Query: 437  NYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPSFRF 309
            NYLDPRITVAWCKRHEVPIEKIFNKSLLAKF W+MDVDPSFRF
Sbjct: 885  NYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWSMDVDPSFRF 927


>dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]
          Length = 920

 Score = 1142 bits (2954), Expect = 0.0
 Identities = 605/921 (65%), Positives = 680/921 (73%), Gaps = 33/921 (3%)
 Frame = -3

Query: 2993 MAVEACSXXXXXXXXXXXXXXLVFKRXXXXXXXXXXXXXXXXXXXXQKHDRQLGRPMPDV 2814
            MAVEAC+              ++FKR                     KH  Q      DV
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQ-KHVGQSAVHTSDV 59

Query: 2813 RSQNGKSSVVQKGKMAFSSKSPPVKSPLRSPEASNSSAKAYPLRPPEANLRPSAAYRS-- 2640
            R  NG++S  QKG++  S+K+PPVKSPL SP+ASNSSAKA P+  P AN +PSA+  S  
Sbjct: 60   RPANGENSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATSTA 119

Query: 2639 --DNVNRPMKV---GKPSIGSATEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXXXS 2475
               N ++        KPS+ +A   ++S+ S+D+KPLSAR                   S
Sbjct: 120  KQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDS 179

Query: 2474 RLGQKPSIPKLEDSDDEKPLSSKVQLKSNVGTSYASKSYDSDEDKPLVAKNNQNGSALRD 2295
               ++P I + EDS+DEKPLS +   KS++G S  SKSYDSDE KPL AK   NGSA RD
Sbjct: 180  CSIRRPVIEESEDSEDEKPLSRRFTSKSSLGES-TSKSYDSDEKKPLAAKVQPNGSASRD 238

Query: 2294 SSSKKPSTMLSKRPASEIKSAGQSSVKKHKLSNASVPINNKQASVKAEPKVEDDDDHVPI 2115
            S   K +++ +KRP  E+KS  QSS+KK KLS+    I+NKQA+VK EPK EDDDD++P+
Sbjct: 239  SPMNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPL 298

Query: 2114 SQRMKK-------------------------PATADKKSSAVKNVTXXXXXXXXXXXXXX 2010
            SQR KK                         PA+  K S+ VK  +              
Sbjct: 299  SQRGKKSQTATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKS 358

Query: 2009 XXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQE 1830
                          VPPGSGEGQKWTTL+HNGVIFPPPY+PHGVK+LYK +P+ LTPEQE
Sbjct: 359  KKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQE 418

Query: 1829 EVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFTPIYEWHQXXXXXX 1650
            EVATMFAVMLDT+YM+KP+FKENF SDW+K+LGKNH IQNLEDCDF PIYEWHQ      
Sbjct: 419  EVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKK 478

Query: 1649 XXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRR 1470
                                KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+R
Sbjct: 479  KQMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR 538

Query: 1469 IRPSDITINIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASST 1290
            IRP DITINIGKDAPIPECPIPGERWKE+R+DNTVTWLA+WNDPIN KEFKYVFLAASST
Sbjct: 539  IRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAASST 598

Query: 1289 LKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATYLIDKLALRAGNEK 1113
            LKGQSDKEKYEK+RLLKDYI GIRAAYTKDF + KD  KKQIAVATYLIDKLALRAGNEK
Sbjct: 599  LKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEK 658

Query: 1112 DDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKK 933
            DDDEADTVGCCTLKVENVEP+PPNILKFDFLGKDSIRYQNEV+VEPAVFKAI QFRSGK+
Sbjct: 659  DDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIHQFRSGKE 718

Query: 932  AGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQ 753
              +D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS++T GG+VAE VVVYQ
Sbjct: 719  GSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKKTNGGEVAEKVVVYQ 778

Query: 752  HANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADG 573
            HANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  LEEL TDLSRAKKGKP  K ADG
Sbjct: 779  HANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPLSKGADG 838

Query: 572  KPKRNLNPEALEKKISQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH 393
            KPKRNLNPEALE+KI+QTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH
Sbjct: 839  KPKRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH 898

Query: 392  EVPIEKIFNKSLLAKFTWAMD 330
            EVPIEKIFNKSLLAKF WAM+
Sbjct: 899  EVPIEKIFNKSLLAKFAWAMN 919


>dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. glabra]
          Length = 920

 Score = 1140 bits (2948), Expect = 0.0
 Identities = 604/921 (65%), Positives = 680/921 (73%), Gaps = 33/921 (3%)
 Frame = -3

Query: 2993 MAVEACSXXXXXXXXXXXXXXLVFKRXXXXXXXXXXXXXXXXXXXXQKHDRQLGRPMPDV 2814
            MAVEAC+              ++FKR                     +H  Q      DV
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQ-RHVGQSAVHTSDV 59

Query: 2813 RSQNGKSSVVQKGKMAFSSKSPPVKSPLRSPEASNSSAKAYPLRPPEANLRPSAAYRS-- 2640
            R  NG++S  QKG++  S+K+PPVKSPL SP+ASNSSAKA P+    AN +PSA+  S  
Sbjct: 60   RPANGENSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSAGANSKPSASATSTA 119

Query: 2639 --DNVNRPMKV---GKPSIGSATEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXXXS 2475
               N ++        KPS+ +A   ++S+ S+D+KPLSAR                   S
Sbjct: 120  KQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDS 179

Query: 2474 RLGQKPSIPKLEDSDDEKPLSSKVQLKSNVGTSYASKSYDSDEDKPLVAKNNQNGSALRD 2295
               ++P I + EDS+DEKPLS +   KS++G S  SKSYDSDE KPL AK   NGSA RD
Sbjct: 180  CSIRRPVIEESEDSEDEKPLSRRFTSKSSLGES-TSKSYDSDEKKPLAAKVQPNGSASRD 238

Query: 2294 SSSKKPSTMLSKRPASEIKSAGQSSVKKHKLSNASVPINNKQASVKAEPKVEDDDDHVPI 2115
            S   K +++ +KRP  E+KS  QSS+KK KLS+    I+NKQA+VK EPK EDDDD++P+
Sbjct: 239  SPMNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPL 298

Query: 2114 SQRMKK-------------------------PATADKKSSAVKNVTXXXXXXXXXXXXXX 2010
            SQR KK                         PA+  K S+ VK  +              
Sbjct: 299  SQRGKKSQTATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKS 358

Query: 2009 XXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQE 1830
                          VPPGSGEGQKWTTL+HNGVIFPPPY+PHGVK+LYK +P+ LTPEQE
Sbjct: 359  KKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQE 418

Query: 1829 EVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFTPIYEWHQXXXXXX 1650
            EVATMFAVMLDT+YM+KP+FKENF SDW+K+LGKNH IQNLEDCDF PIYEWHQ      
Sbjct: 419  EVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKK 478

Query: 1649 XXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRR 1470
                                KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+R
Sbjct: 479  KQMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR 538

Query: 1469 IRPSDITINIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASST 1290
            IRP DITINIGKDAPIPECPIPGERWKE+R+DNTVTWLA+WNDPIN KEFKYVFLAASST
Sbjct: 539  IRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAASST 598

Query: 1289 LKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATYLIDKLALRAGNEK 1113
            LKGQSDKEKYEK+RLLKDYI GIRAAYTKDF + KD  KKQIAVATYLIDKLALRAGNEK
Sbjct: 599  LKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEK 658

Query: 1112 DDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKK 933
            DDDEADTVGCCTLKVENVEP+PPNILKFDFLGKDSIRYQNEV+VEPAVFKAIQQFRSGK+
Sbjct: 659  DDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKE 718

Query: 932  AGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQ 753
              +D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS++T GG+VAE VVVYQ
Sbjct: 719  GSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKKTNGGEVAEKVVVYQ 778

Query: 752  HANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADG 573
            HANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  LEEL TDLSRAKKGKP  K ADG
Sbjct: 779  HANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPLSKGADG 838

Query: 572  KPKRNLNPEALEKKISQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH 393
            KPKRNLNPEALE+KI+QTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH
Sbjct: 839  KPKRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH 898

Query: 392  EVPIEKIFNKSLLAKFTWAMD 330
            EVPIEKIFNKSLLAKF WAM+
Sbjct: 899  EVPIEKIFNKSLLAKFAWAMN 919


>dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]
          Length = 926

 Score = 1134 bits (2932), Expect = 0.0
 Identities = 602/928 (64%), Positives = 680/928 (73%), Gaps = 33/928 (3%)
 Frame = -3

Query: 2993 MAVEACSXXXXXXXXXXXXXXLVFKRXXXXXXXXXXXXXXXXXXXXQKHDRQLGRPMPDV 2814
            MAVEAC+              ++FKR                     KH  Q      DV
Sbjct: 1    MAVEACTTPNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQ-KHVGQSAVHTSDV 59

Query: 2813 RSQNGKSSVVQKGKMAFSSKSPPVKSPLRSPEASNSSAKAYPLRPPEANLRPSAAYRS-- 2640
            R  NG+SS  QKG++  S+++PPVKSPL SP+ASNSSAKA P+  P AN + SA+  S  
Sbjct: 60   RPANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTA 119

Query: 2639 --DNVNRPMKV---GKPSIGSATEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXXXS 2475
               N ++        KPS+ +A   ++S+ S+D+KPL AR S                 S
Sbjct: 120  KQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDS 179

Query: 2474 RLGQKPSIPKLEDSDDEKPLSSKVQLKSNVGTSYASKSYDSDEDKPLVAKNNQNGSALRD 2295
               ++P I + EDS+DEKPLS +   KS++G S  SKSYDSDE KPL  K  QNGSA RD
Sbjct: 180  CSIRRPVIEESEDSEDEKPLSRRFPSKSSLGES-TSKSYDSDEKKPLATKVQQNGSASRD 238

Query: 2294 SSSKKPSTMLSKRPASEIKSAGQSSVKKHKLSNASVPINNKQASVKAEPKVEDDDDHVPI 2115
                K +++L+KR   E+KS  QSS+KK KLS+    I+NKQA+VK EPK EDDDD++P+
Sbjct: 239  GPMNKSASLLNKRAPGEVKSLNQSSLKKAKLSSPITSISNKQAAVKPEPKAEDDDDNIPL 298

Query: 2114 SQRMKK-------------------------PATADKKSSAVKNVTXXXXXXXXXXXXXX 2010
            SQR KK                         PA+  K S+ VK  +              
Sbjct: 299  SQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKS 358

Query: 2009 XXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQE 1830
                          VPPGSGEGQKWTTL+HNGV+F PPY+PHGVK+LYK +P+ LTPEQE
Sbjct: 359  KKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFLPPYKPHGVKMLYKXQPLTLTPEQE 418

Query: 1829 EVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFTPIYEWHQXXXXXX 1650
            EVATMFAVMLDT+YM+KP+FKENF SDW+K+LGKNH +QNLEDCDF PIYEWHQ      
Sbjct: 419  EVATMFAVMLDTDYMTKPRFKENFFSDWKKMLGKNHTVQNLEDCDFGPIYEWHQQEKEKR 478

Query: 1649 XXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRR 1470
                                KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+R
Sbjct: 479  KQMTTEEKKALKEERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR 538

Query: 1469 IRPSDITINIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASST 1290
            IRP DITINIGKDAPIPECPIPGERWKE+R+DNTVTWLAFWNDPIN KE KYVFLAASST
Sbjct: 539  IRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWNDPINQKECKYVFLAASST 598

Query: 1289 LKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATYLIDKLALRAGNEK 1113
            LKGQSDKEKYEK+RLLKDYI GIRAAYTKDF + KD  KKQIAVATYLIDKLALRAGNEK
Sbjct: 599  LKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEK 658

Query: 1112 DDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKK 933
            DDDEADTVGCCTLKVENVEP+PPNILK DF+GKDSIRYQNEV+VEPAVFKAIQQFRSGK+
Sbjct: 659  DDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKE 718

Query: 932  AGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQ 753
               D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS+ETKGG VAE V VYQ
Sbjct: 719  GCADLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQ 778

Query: 752  HANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADG 573
            HANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  LEEL TDLSRAKKGKPP K ADG
Sbjct: 779  HANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPAKGADG 838

Query: 572  KPKRNLNPEALEKKISQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH 393
            +PKRNLNPE+LE+KI+QTNAKIEKMERDK+TKEDLK VAL TSKI+YLDPRITVAWCKRH
Sbjct: 839  EPKRNLNPESLERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRH 898

Query: 392  EVPIEKIFNKSLLAKFTWAMDVDPSFRF 309
            EVPIEKIFNKSLLAKF W+MDVDPSFRF
Sbjct: 899  EVPIEKIFNKSLLAKFAWSMDVDPSFRF 926


>dbj|BAK32956.1| topoisomerase I [Ophiorrhiza fucosa]
          Length = 926

 Score = 1125 bits (2911), Expect = 0.0
 Identities = 597/928 (64%), Positives = 676/928 (72%), Gaps = 33/928 (3%)
 Frame = -3

Query: 2993 MAVEACSXXXXXXXXXXXXXXLVFKRXXXXXXXXXXXXXXXXXXXXQKHDRQLGRPMPDV 2814
            MAVEAC+              ++FKR                     KH  Q      DV
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQ-KHVGQSAVHTSDV 59

Query: 2813 RSQNGKSSVVQKGKMAFSSKSPPVKSPLRSPEASNSSAKAYPLRPPEANLRPSAAYRS-- 2640
            R  NG+SS  QKG++  S+++PPVKSPL SP+ASNSSAKA P+  P AN + SA+  S  
Sbjct: 60   RPANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTA 119

Query: 2639 --DNVNRPMKV---GKPSIGSATEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXXXS 2475
               N ++        KPS+  A   ++S+ S+D+KPL AR S                 S
Sbjct: 120  KQQNHHKSSAAFIEPKPSVPPAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDS 179

Query: 2474 RLGQKPSIPKLEDSDDEKPLSSKVQLKSNVGTSYASKSYDSDEDKPLVAKNNQNGSALRD 2295
               ++P + + EDS+DEKPLS +   KS++G S  SKSYDSDE KPL AK  QNGSA RD
Sbjct: 180  CSIRRPVVEESEDSEDEKPLSRRFPSKSSLGES-TSKSYDSDEKKPLAAKVQQNGSASRD 238

Query: 2294 SSSKKPSTMLSKRPASEIKSAGQSSVKKHKLSNASVPINNKQASVKAEPKVEDDDDHVPI 2115
                K +++ +KR   E+KS  QSS+KK KLS+    I+NKQA+VK EPK EDDDD++P+
Sbjct: 239  GPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPL 298

Query: 2114 SQRMKK-------------------------PATADKKSSAVKNVTXXXXXXXXXXXXXX 2010
            SQR KK                         PA+  K S+ VK  +              
Sbjct: 299  SQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKS 358

Query: 2009 XXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQE 1830
                          VPPGSGEGQKWTTL+HNGV+FPPPY+PHGVK+LYK +P+ LTPEQE
Sbjct: 359  KKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQE 418

Query: 1829 EVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFTPIYEWHQXXXXXX 1650
            EVATMFA MLDT+YM+KP+FKENF SDW+KILGKNH IQNLEDCDF PIYEWHQ      
Sbjct: 419  EVATMFAAMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEREKK 478

Query: 1649 XXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRR 1470
                                KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLK+R
Sbjct: 479  KQMTTEEKKALKDERLQLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKR 538

Query: 1469 IRPSDITINIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASST 1290
            I P DITINIGKDAPIPECPIPGERWKE+R+DNTVTWLA+WNDP+N KE KYVFLA SST
Sbjct: 539  IHPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPSST 598

Query: 1289 LKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATYLIDKLALRAGNEK 1113
            LKGQSDKEKYEK+RLLKDYI GIRAAYTKDF + KD  KKQIAVATYLIDKLALRAGNEK
Sbjct: 599  LKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEK 658

Query: 1112 DDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKK 933
            DDDEADTVGCCTLKVENVEP+PPNILK DF+GKDSIRYQNEV+VEPAVFKAIQQFRSGK+
Sbjct: 659  DDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKE 718

Query: 932  AGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQ 753
              +D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS+ETKGG VAE V VYQ
Sbjct: 719  GSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQ 778

Query: 752  HANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADG 573
            HANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  LEEL TDLSRAKKGKPP K  DG
Sbjct: 779  HANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDG 838

Query: 572  KPKRNLNPEALEKKISQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH 393
            +PKRNLNPEALE+KI+QTNAKIEKMERDK+TKEDLK VAL TSKI+YLDPRITVAWCKR 
Sbjct: 839  EPKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQ 898

Query: 392  EVPIEKIFNKSLLAKFTWAMDVDPSFRF 309
            EVPIEK+FNKSLLAKF WAMDVDPSFRF
Sbjct: 899  EVPIEKMFNKSLLAKFAWAMDVDPSFRF 926


>dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]
          Length = 926

 Score = 1125 bits (2911), Expect = 0.0
 Identities = 597/928 (64%), Positives = 678/928 (73%), Gaps = 33/928 (3%)
 Frame = -3

Query: 2993 MAVEACSXXXXXXXXXXXXXXLVFKRXXXXXXXXXXXXXXXXXXXXQKHDRQLGRPMPDV 2814
            MAVEAC+              ++FKR                     KH  Q      DV
Sbjct: 1    MAVEACTTPNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQ-KHVGQSAVHTSDV 59

Query: 2813 RSQNGKSSVVQKGKMAFSSKSPPVKSPLRSPEASNSSAKAYPLRPPEANLRPSAAYRS-- 2640
            R  NG+SS  QKG++  S+++PPVKSPL SP+ASNSSAKA P+  P AN + SA+  S  
Sbjct: 60   RPANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTA 119

Query: 2639 --DNVNRPMKV---GKPSIGSATEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXXXS 2475
               N ++        KPS+ +A   ++S+ S+D+KPL AR S                 S
Sbjct: 120  KQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDS 179

Query: 2474 RLGQKPSIPKLEDSDDEKPLSSKVQLKSNVGTSYASKSYDSDEDKPLVAKNNQNGSALRD 2295
               ++P I + EDS+DEKPLS +   KS++G S  SKS+DSDE KPL AK  QNGSA RD
Sbjct: 180  CSIRRPVIEESEDSEDEKPLSRRFPSKSSLGES-TSKSHDSDEKKPLAAKVQQNGSASRD 238

Query: 2294 SSSKKPSTMLSKRPASEIKSAGQSSVKKHKLSNASVPINNKQASVKAEPKVEDDDDHVPI 2115
                K +++ +KR   E+KS  QSS+KK KLS+    I+NKQA+VK EPK EDDDD++P+
Sbjct: 239  GPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSTITSISNKQAAVKPEPKAEDDDDNIPL 298

Query: 2114 SQRMKK-------------------------PATADKKSSAVKNVTXXXXXXXXXXXXXX 2010
            SQR KK                         PA+  K S+ VK  +              
Sbjct: 299  SQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKS 358

Query: 2009 XXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQE 1830
                          VPPGSGEGQKWTTL+HNGV+FPPPY+PHGVK+LYK +P+ LTPEQE
Sbjct: 359  KKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQE 418

Query: 1829 EVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFTPIYEWHQXXXXXX 1650
            EVATMFA MLDT+YM+KP+FKENF SDW+KILGKNH IQNLEDCDF PIYEWHQ      
Sbjct: 419  EVATMFAAMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEKEKK 478

Query: 1649 XXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRR 1470
                                KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLK+R
Sbjct: 479  KQMTTEEKKALKEERLQLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKR 538

Query: 1469 IRPSDITINIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASST 1290
            IRP DITINIGKDAPIPECPIPGERWKE+R+DNTVTWLA+WNDP+N KE KYVFLAASST
Sbjct: 539  IRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAASST 598

Query: 1289 LKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATYLIDKLALRAGNEK 1113
            LKGQSDKEKYEK+RLLKDYI GIRAAYTKDF + KD  KKQ+AVATYLIDKLALRAGNEK
Sbjct: 599  LKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQVAVATYLIDKLALRAGNEK 658

Query: 1112 DDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKK 933
            DDDEADTVGCCTLKVENVEP+PPNILK DF+GKDSIRYQNEV+VEPAVFKAIQQFRSGK+
Sbjct: 659  DDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKE 718

Query: 932  AGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQ 753
              +D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS+ETKGG VAE V VYQ
Sbjct: 719  GSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQ 778

Query: 752  HANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADG 573
             ANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  LEEL TDLSRAKKGKPP K  DG
Sbjct: 779  RANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDG 838

Query: 572  KPKRNLNPEALEKKISQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH 393
            +PKRNLNPEALE+KI+QTNAKIEKMERDK+TKEDLK VAL TSKI+YLDPRITVAWCKR 
Sbjct: 839  EPKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQ 898

Query: 392  EVPIEKIFNKSLLAKFTWAMDVDPSFRF 309
            EVPIEK+FNKSLLAKF WAMDVDPSFRF
Sbjct: 899  EVPIEKMFNKSLLAKFAWAMDVDPSFRF 926


>dbj|BAK32961.1| topoisomerase I [Ophiorrhiza ridleyana]
          Length = 926

 Score = 1121 bits (2899), Expect = 0.0
 Identities = 594/928 (64%), Positives = 677/928 (72%), Gaps = 33/928 (3%)
 Frame = -3

Query: 2993 MAVEACSXXXXXXXXXXXXXXLVFKRXXXXXXXXXXXXXXXXXXXXQKHDRQLGRPMPDV 2814
            MAVEAC+              ++FKR                     KH  Q      DV
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPTSKQNQANAEKKKLSLQ-KHVGQSAVHTSDV 59

Query: 2813 RSQNGKSSVVQKGKMAFSSKSPPVKSPLRSPEASNSSAKAYPLRPPEANLRPSAAYRS-- 2640
            R  NG+SS  QKG++  S+++PPVKSPL SP+ASNSSAKA P+  P AN + SA+  S  
Sbjct: 60   RPANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTA 119

Query: 2639 --DNVNRPMKV---GKPSIGSATEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXXXS 2475
               N ++        KPS+ +A   ++S+ S+D+KPL AR S                 S
Sbjct: 120  KQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSMGKSNHANKEGGDS 179

Query: 2474 RLGQKPSIPKLEDSDDEKPLSSKVQLKSNVGTSYASKSYDSDEDKPLVAKNNQNGSALRD 2295
               ++P I + EDS+DEKPLS +   KS++G S  SKSYDSDE KPL AK  QNGSA  +
Sbjct: 180  CSIRRPVIEESEDSEDEKPLSRRFPSKSSLGES-TSKSYDSDEKKPLAAKVQQNGSASPE 238

Query: 2294 SSSKKPSTMLSKRPASEIKSAGQSSVKKHKLSNASVPINNKQASVKAEPKVEDDDDHVPI 2115
                K +++ +KR   E+KS  QSS+KK KLS+    I+NKQA+VK EPK EDDDD++P+
Sbjct: 239  GPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPL 298

Query: 2114 SQRMKK-------------------------PATADKKSSAVKNVTXXXXXXXXXXXXXX 2010
            SQR KK                         P +  K S+ VK  +              
Sbjct: 299  SQRGKKSQTAASKPKDEDDDHAPISQRIKKSPVSVSKSSAPVKKASTVVSTSLKKVNKKS 358

Query: 2009 XXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQE 1830
                          VPPGSGEGQKWTTL+HNGV+FPPPY+PHGVK+LYK +P+ LTPEQE
Sbjct: 359  KKVIRKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQE 418

Query: 1829 EVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFTPIYEWHQXXXXXX 1650
            EVATMFAVMLDT+YM+KP+FKENF SDW+KILGKNH IQNLEDCDF PIYEWHQ      
Sbjct: 419  EVATMFAVMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEKEKK 478

Query: 1649 XXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRR 1470
                                KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLK+R
Sbjct: 479  KQMTTEEKKALKEERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKR 538

Query: 1469 IRPSDITINIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASST 1290
            IRP DITINIGKDAPIPECPIPGERWKE+R+DNTVTWLA+WNDP+N KE KYVFLAASST
Sbjct: 539  IRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNIKECKYVFLAASST 598

Query: 1289 LKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATYLIDKLALRAGNEK 1113
            LKGQS KEKYEK+R+LKDYI GIRAAYTK F + KD  KKQIAVATYLIDKLALRAGNEK
Sbjct: 599  LKGQSVKEKYEKARVLKDYIHGIRAAYTKGFTNNKDPMKKQIAVATYLIDKLALRAGNEK 658

Query: 1112 DDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKK 933
            DDDEADTVGCCTLKVENVEP+PPNILK DF+GKDSIRYQNEV+VEPAVFKAIQQFRSGK+
Sbjct: 659  DDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKE 718

Query: 932  AGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQ 753
              +D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS+ETKGG +AE V VYQ
Sbjct: 719  GSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKIAEKVAVYQ 778

Query: 752  HANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADG 573
            HANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  LEEL TDLSRAKKGKPP K ADG
Sbjct: 779  HANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKDADG 838

Query: 572  KPKRNLNPEALEKKISQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH 393
            +PKRNLNPE+LE+KI+QTNAKIEKMERDK+TKEDLK VAL TSKI+YLDPRITVAWCKR 
Sbjct: 839  EPKRNLNPESLERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQ 898

Query: 392  EVPIEKIFNKSLLAKFTWAMDVDPSFRF 309
            EVPIEK+FNKSLLAKF WAMDVDPSFRF
Sbjct: 899  EVPIEKMFNKSLLAKFAWAMDVDPSFRF 926


>dbj|BAK32959.1| topoisomerase I [Ophiorrhiza plumbea]
          Length = 920

 Score = 1110 bits (2871), Expect = 0.0
 Identities = 591/921 (64%), Positives = 669/921 (72%), Gaps = 33/921 (3%)
 Frame = -3

Query: 2993 MAVEACSXXXXXXXXXXXXXXLVFKRXXXXXXXXXXXXXXXXXXXXQKHDRQLGRPMPDV 2814
            MAVEAC+              ++FKR                     KH  Q      DV
Sbjct: 1    MAVEACTTPNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQ-KHVGQSAVHTSDV 59

Query: 2813 RSQNGKSSVVQKGKMAFSSKSPPVKSPLRSPEASNSSAKAYPLRPPEANLRPSAAYRS-- 2640
            R  NG+SS  QKG++  S+++PPVKSPL SP+ASNSSAKA P+  P AN + SA+  S  
Sbjct: 60   RPANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTA 119

Query: 2639 --DNVNRPMKV---GKPSIGSATEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXXXS 2475
               N ++        KPS+ +A   ++S+ S+D+KPL AR S                 S
Sbjct: 120  KQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDS 179

Query: 2474 RLGQKPSIPKLEDSDDEKPLSSKVQLKSNVGTSYASKSYDSDEDKPLVAKNNQNGSALRD 2295
               ++P I + EDS+DEKPLS +   KS++G S  SKSYDSDE KPL AK   NGSA RD
Sbjct: 180  CSIRRPVIEESEDSEDEKPLSRRFPSKSSLGES-TSKSYDSDEKKPLAAKVQPNGSASRD 238

Query: 2294 SSSKKPSTMLSKRPASEIKSAGQSSVKKHKLSNASVPINNKQASVKAEPKVEDDDDHVPI 2115
                K +++ +KR   E+KS  QSS+KK KLS+    I+NKQA+VK EPK EDDDD++P+
Sbjct: 239  GPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPL 298

Query: 2114 SQRMKK-------------------------PATADKKSSAVKNVTXXXXXXXXXXXXXX 2010
            SQR KK                         PA+  K S+ VK  +              
Sbjct: 299  SQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKS 358

Query: 2009 XXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQE 1830
                          VPPGSGEGQKWTTL+HNGVIFPPPY+PHGVK+LYK +P+ LTPEQE
Sbjct: 359  KKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQE 418

Query: 1829 EVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFTPIYEWHQXXXXXX 1650
            EVATMFAVMLDT+YM+KP+FKENF SDW+K+LGKNH IQNLEDCDF PIYEWHQ      
Sbjct: 419  EVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKK 478

Query: 1649 XXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRR 1470
                                KYMW IV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLK+R
Sbjct: 479  KQMTTEEKKALKEERLQQEEKYMWVIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKR 538

Query: 1469 IRPSDITINIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASST 1290
            IRP DITINIGKDAPIPECPIPGERWKE+R+DNTVTWLA+WNDPIN KE KYVFL ASST
Sbjct: 539  IRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKERKYVFLGASST 598

Query: 1289 LKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATYLIDKLALRAGNEK 1113
            LKGQSDKEKYEK+RLLKDYI GIRAAYTKDF + KD  KKQIAVATYLIDKLALRAGNEK
Sbjct: 599  LKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEK 658

Query: 1112 DDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKK 933
            DDDEADTVGCCTLKVENVEP+PPNILK DF+GKDSIRYQNEV+VEPAVFKAIQQFRSGK+
Sbjct: 659  DDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKE 718

Query: 932  AGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQ 753
               D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS+ETKGG VAE V VYQ
Sbjct: 719  GSADLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQ 778

Query: 752  HANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADG 573
            HANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  LEEL TDLSRAKKGKPP K ADG
Sbjct: 779  HANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGADG 838

Query: 572  KPKRNLNPEALEKKISQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH 393
            +PKRNLNPEALE+KI+QTNAKIEKME DK+TKEDLK VAL TSKI+YL PRITVAWCKRH
Sbjct: 839  EPKRNLNPEALERKIAQTNAKIEKMEGDKKTKEDLKAVALSTSKISYLGPRITVAWCKRH 898

Query: 392  EVPIEKIFNKSLLAKFTWAMD 330
            EVPIEK+FNKSLLAKF WAM+
Sbjct: 899  EVPIEKMFNKSLLAKFAWAMN 919


>dbj|BAK32963.1| topoisomerase I [Ophiorrhiza sp. 35]
          Length = 920

 Score = 1109 bits (2869), Expect = 0.0
 Identities = 589/921 (63%), Positives = 670/921 (72%), Gaps = 33/921 (3%)
 Frame = -3

Query: 2993 MAVEACSXXXXXXXXXXXXXXLVFKRXXXXXXXXXXXXXXXXXXXXQKHDRQLGRPMPDV 2814
            MAVEAC+              ++FKR                     KH  Q      DV
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQ-KHVGQSAVHTSDV 59

Query: 2813 RSQNGKSSVVQKGKMAFSSKSPPVKSPLRSPEASNSSAKAYPLRPPEANLRPSAAYRS-- 2640
            R  NG+SS  QKG++  S+++PPVKSPL SP+ASNSSAKA P+  P AN + SA+  S  
Sbjct: 60   RPANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTA 119

Query: 2639 --DNVNRPMKV---GKPSIGSATEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXXXS 2475
               N ++        KPS+  A   ++S+ S+D+KPL AR S                 S
Sbjct: 120  KQQNHHKSSAAFIEPKPSVPPAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDS 179

Query: 2474 RLGQKPSIPKLEDSDDEKPLSSKVQLKSNVGTSYASKSYDSDEDKPLVAKNNQNGSALRD 2295
               ++P + + EDS+DEKPLS +   KS++G S  SKSYDSDE KPL AK  QNGSA RD
Sbjct: 180  CSIRRPVVEESEDSEDEKPLSRRFPSKSSLGES-TSKSYDSDEKKPLAAKVQQNGSASRD 238

Query: 2294 SSSKKPSTMLSKRPASEIKSAGQSSVKKHKLSNASVPINNKQASVKAEPKVEDDDDHVPI 2115
                K +++ +KR   E+KS  QSS+KK KLS+    I+NKQA+VK EPK EDDDD++P+
Sbjct: 239  GPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPL 298

Query: 2114 SQRMKK-------------------------PATADKKSSAVKNVTXXXXXXXXXXXXXX 2010
            SQR KK                         PA+  K S+ VK  +              
Sbjct: 299  SQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKS 358

Query: 2009 XXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQE 1830
                          VPPGSGEGQKWTTL+HNGVIFPPPY+PHGVK+LYK +P+ LTPEQE
Sbjct: 359  KKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPLTLTPEQE 418

Query: 1829 EVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFTPIYEWHQXXXXXX 1650
            EVATMFAVMLDT+YM+KP+FKENF SDW+K+LGKNH IQNLEDCDF PIYEWHQ      
Sbjct: 419  EVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEREKK 478

Query: 1649 XXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRR 1470
                                KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLK+R
Sbjct: 479  KQMTTEEKKALKDERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKR 538

Query: 1469 IRPSDITINIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASST 1290
            I P DITINIGKDAPIPECPIPGERWKE+R+DNTVTWLA+WNDP+N KE KYVFLA SST
Sbjct: 539  IHPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPSST 598

Query: 1289 LKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATYLIDKLALRAGNEK 1113
            LKGQSDKEKYEK+RLLKDYI GIRAAYTKDF + KD  KKQIAVATYLIDKLALRAGNEK
Sbjct: 599  LKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEK 658

Query: 1112 DDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKK 933
            DDDEADTVGCCTL+VENVEP+PPNILK DF+GKDSIRYQNEV+VEPAVFKAIQQFRSGK+
Sbjct: 659  DDDEADTVGCCTLRVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKE 718

Query: 932  AGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQ 753
              +D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS+ETKGG VAE V VYQ
Sbjct: 719  GSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQ 778

Query: 752  HANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADG 573
            HANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  LEEL TDLSRAKKGKPP K  DG
Sbjct: 779  HANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDG 838

Query: 572  KPKRNLNPEALEKKISQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH 393
            +PKRNLNPEALE+KI+QTNAKIEKMERDK+TKEDLK VAL TSKI+YLDPRITVAWCKR 
Sbjct: 839  EPKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQ 898

Query: 392  EVPIEKIFNKSLLAKFTWAMD 330
            EVPIEK+FNKSLLAKF WAM+
Sbjct: 899  EVPIEKMFNKSLLAKFAWAMN 919


>dbj|BAK32957.1| topoisomerase I [Ophiorrhiza harrisiana]
          Length = 920

 Score = 1100 bits (2844), Expect = 0.0
 Identities = 586/921 (63%), Positives = 668/921 (72%), Gaps = 33/921 (3%)
 Frame = -3

Query: 2993 MAVEACSXXXXXXXXXXXXXXLVFKRXXXXXXXXXXXXXXXXXXXXQKHDRQLGRPMPDV 2814
            MAVEAC+              ++FKR                     KH  Q      DV
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQ-KHVGQSAVHTSDV 59

Query: 2813 RSQNGKSSVVQKGKMAFSSKSPPVKSPLRSPEASNSSAKAYPLRPPEANLRPSAAYRS-- 2640
            R  NG+SS  QKG++  S+++PPVKSPL SP+ASNSSAKA P+  P AN + SA+  S  
Sbjct: 60   RPANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTA 119

Query: 2639 --DNVNRPMKV---GKPSIGSATEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXXXS 2475
               N ++        KPS+  A   ++S+ S+D+KPL AR S                 S
Sbjct: 120  KQQNHHKSSAAFIEPKPSVPPAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDS 179

Query: 2474 RLGQKPSIPKLEDSDDEKPLSSKVQLKSNVGTSYASKSYDSDEDKPLVAKNNQNGSALRD 2295
               ++P + + EDS+DEKPLS +   KS++G S  SKSYDSDE KPL AK  QNGSA RD
Sbjct: 180  CSIRRPVVEESEDSEDEKPLSRRFPSKSSLGES-TSKSYDSDEKKPLAAKVQQNGSASRD 238

Query: 2294 SSSKKPSTMLSKRPASEIKSAGQSSVKKHKLSNASVPINNKQASVKAEPKVEDDDDHVPI 2115
                K +++ +KR   E+KS  QSS+KK KLS+    I+NKQA+VK EPK EDDDD++P+
Sbjct: 239  GPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPL 298

Query: 2114 SQRMKK-------------------------PATADKKSSAVKNVTXXXXXXXXXXXXXX 2010
            SQR KK                         PA+  K S+ VK  +              
Sbjct: 299  SQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKS 358

Query: 2009 XXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQE 1830
                          VPPGSGEGQKWTTL+HNGV+F PPY+PHGVK+LYK +P+ LTPEQE
Sbjct: 359  KKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFLPPYKPHGVKMLYKQQPLTLTPEQE 418

Query: 1829 EVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFTPIYEWHQXXXXXX 1650
            EVATMFAVMLDT+YM+KP+FKENF SDW+K+LGKNH +QNLEDCDF PIYEWHQ      
Sbjct: 419  EVATMFAVMLDTDYMTKPRFKENFFSDWKKMLGKNHTVQNLEDCDFGPIYEWHQQEKEKR 478

Query: 1649 XXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRR 1470
                                KYM AIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLK+R
Sbjct: 479  KQMTTEEKKALKEERLQQEEKYMRAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKR 538

Query: 1469 IRPSDITINIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASST 1290
            I P DITINIGKDAPIPECPIPGERWKE+R+DNTVTWLA+WNDP+N KE KYVFLA SST
Sbjct: 539  IHPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPSST 598

Query: 1289 LKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATYLIDKLALRAGNEK 1113
            LKGQSDKEKYEK+RLLKDYI GIRAAYTKDF + KD  KKQIAVATYLIDKLALRAGNEK
Sbjct: 599  LKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEK 658

Query: 1112 DDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKK 933
            DDDEADTVGCCTLKVENVEP+PPNILK DF+GKDSIRYQNEV+VEPAVFKAIQQFRSGK+
Sbjct: 659  DDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKE 718

Query: 932  AGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQ 753
              +D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS+ETKGG VAE V VYQ
Sbjct: 719  GSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQ 778

Query: 752  HANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADG 573
            HANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  LEEL TDLSRAKKGKPP K  DG
Sbjct: 779  HANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDG 838

Query: 572  KPKRNLNPEALEKKISQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH 393
            +PKRNLNPEALE+KI+QTNAKIEKMERDK+TKEDLK VAL TSKI+YLDPRITVAWCKR 
Sbjct: 839  EPKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQ 898

Query: 392  EVPIEKIFNKSLLAKFTWAMD 330
            EVPIEK+FNKSLLAKF WAM+
Sbjct: 899  EVPIEKMFNKSLLAKFAWAMN 919


>ref|XP_007020664.1| DNA topoisomerase I alpha isoform 1 [Theobroma cacao]
            gi|590606147|ref|XP_007020665.1| DNA topoisomerase I
            alpha isoform 1 [Theobroma cacao]
            gi|508720292|gb|EOY12189.1| DNA topoisomerase I alpha
            isoform 1 [Theobroma cacao] gi|508720293|gb|EOY12190.1|
            DNA topoisomerase I alpha isoform 1 [Theobroma cacao]
          Length = 904

 Score = 1082 bits (2797), Expect = 0.0
 Identities = 575/907 (63%), Positives = 653/907 (71%), Gaps = 12/907 (1%)
 Frame = -3

Query: 2993 MAVEACSXXXXXXXXXXXXXXLVFKRXXXXXXXXXXXXXXXXXXXXQKHDRQLGRPMPDV 2814
            MAVEA +              +VFKR                    Q+ D Q GR + DV
Sbjct: 1    MAVEAPAKHVYDFDDDDDDGPVVFKRNNTSSSKQNQLNSEVKKASSQRSDGQSGRQVSDV 60

Query: 2813 RSQNGKSSVVQKGKMAFSSKSPPVKSPLRSPEASNSSAKAYPLRPPEANLRPSAAYRSD- 2637
            RS NG+SS   K K   SSKSPPVKSP+ SP+AS SS KA P++ P  N + S +     
Sbjct: 61   RSPNGQSSNAPKNKSISSSKSPPVKSPILSPKASTSSTKALPVKSPVVNFKASTSLNDQS 120

Query: 2636 ------NVNRPMKVGKPSIGSATEPNDSDDSEDDK-PLSARLS-TGLXXXXXXXXXXXXX 2481
                  N+   +K G+  I   TEPN  DD +DD  PLSARL                  
Sbjct: 121  KQALKQNMTTAVKEGRSPIKGTTEPNSDDDDDDDSLPLSARLKGISNQGNKGASTSAPAQ 180

Query: 2480 XSRLGQKPSIP-KLEDSDDEKPLSSKVQLKSNVGTSYASKSYDSDEDKPLVAKNNQNGSA 2304
              RL  K  +    ED DDE PLS++  +KSN GTS +S+ +D DE KPL +K  QNGS 
Sbjct: 181  SRRLVPKTEVKVSAEDPDDEAPLSARFNVKSNTGTS-SSRLHDCDEKKPLASKIQQNGSI 239

Query: 2303 LRDSSSKKPSTMLSKRPASEIKSAGQSSVKKHKLSNASVPINNKQASVKAEPKVEDDDDH 2124
            ++    +  ST+  KRP  +  S+  SS KK K S+A   +  KQ +VKAE K ++DDDH
Sbjct: 240  MK-GKQQNSSTLSGKRPLDKGNSSDHSSAKKPKTSDAPTTMKTKQVTVKAE-KADEDDDH 297

Query: 2123 VPISQRMKKPATADKKSSAVKN-VTXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPPGSGE 1947
            +PI+QRMKK   ++ K S++K   T                            VPP SG+
Sbjct: 298  MPIAQRMKKSTASNSKLSSMKQKTTKVVSSSFKKINKKSKKEMKSSKYIKSTKVPPSSGD 357

Query: 1946 GQK-WTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQEEVATMFAVMLDTEYMSKPKF 1770
            GQK W+TL+HNGVIFP PY PHGVK+LY G+PV+LTPEQEEVATMFAVM DT+YMSK +F
Sbjct: 358  GQKKWSTLVHNGVIFPSPYTPHGVKMLYDGRPVDLTPEQEEVATMFAVMKDTDYMSKTQF 417

Query: 1769 KENFMSDWRKILGKNHIIQNLEDCDFTPIYEWHQXXXXXXXXXXXXXXXXXXXXXXXXXX 1590
            K+NF  DW K+LGKNH I++L+ CDFTPIYEWH                           
Sbjct: 418  KKNFWEDWSKLLGKNHTIKDLDRCDFTPIYEWHLQEKEKKKQMSSEEKKALKEEKLKQEE 477

Query: 1589 KYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAPIPECP 1410
            K+MWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAPIPECP
Sbjct: 478  KFMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAPIPECP 537

Query: 1409 IPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKSRLLKDYI 1230
            IPGERWK+I+HDNTVTWLAFWNDPINPKEFKYVFLAASS+LKGQSDKEKYEK+R+LKDYI
Sbjct: 538  IPGERWKDIKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYI 597

Query: 1229 QGIRAAYTKDFASKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPI 1050
            + IRAAYTKDF +KD+ K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NVE I
Sbjct: 598  KNIRAAYTKDFTTKDVMKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGNVECI 657

Query: 1049 PPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKKAGDDIFDKLDTSKLNAHLKEL 870
            PPN LKFDFLGKDSI+Y N VEVE  V+KAI QF++GK   DD+FDKLDTSKLNAHLKEL
Sbjct: 658  PPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKSKSDDLFDKLDTSKLNAHLKEL 717

Query: 869  MPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQHANKEVAIICNHQRTVSKSHS 690
            MPGLTAKVFRTYNASITLDEML++ETK GDVAE VVVYQ ANKEVAIICNHQR++SKSHS
Sbjct: 718  MPGLTAKVFRTYNASITLDEMLNKETKDGDVAEKVVVYQRANKEVAIICNHQRSISKSHS 777

Query: 689  AQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADGKPKRNLNPEALEKKISQTNAK 510
            AQM RL EKI ELKGVL+EL  DL RAKKGKPPLK ADGK KRNL P+A++KKI QTNAK
Sbjct: 778  AQMSRLTEKITELKGVLKELKIDLDRAKKGKPPLKDADGKQKRNLTPQAIQKKIDQTNAK 837

Query: 509  IEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD 330
            IEKMERD +TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF WAMD
Sbjct: 838  IEKMERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMD 897

Query: 329  VDPSFRF 309
            VDP FRF
Sbjct: 898  VDPDFRF 904


>ref|XP_009790344.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 1-like [Nicotiana
            sylvestris]
          Length = 876

 Score = 1075 bits (2781), Expect = 0.0
 Identities = 565/853 (66%), Positives = 638/853 (74%), Gaps = 5/853 (0%)
 Frame = -3

Query: 2852 KHDRQLGRPMPDVRSQNGKSSVVQKGKMAFSSKSPPVKSPLRSPEASNSSAKAYPLRPPE 2673
            K D + GR + DVRS NG++S  QK K   SSK+ P  SP  SP+AS SS++  P   P 
Sbjct: 43   KQDGRSGRQVSDVRSPNGQNSSAQKVKAGTSSKASPAVSPFTSPKASPSSSRISPA--PN 100

Query: 2672 ANLRPSAAYRSDNVNRPMKV----GKPSIGSATEPND-SDDSEDDKPLSARLSTGLXXXX 2508
            +    SA  ++ NVN+  K+     K ++   + PND ++DSEDDKPLSARLS+GL    
Sbjct: 101  SRPSASAGNQAKNVNQQSKIVPNEPKQAVEPKSGPNDEAEDSEDDKPLSARLSSGLSKSI 160

Query: 2507 XXXXXXXXXXSRLGQKPSIPKLEDSDDEKPLSSKVQLKSNVGTSYASKSYDSDEDKPLVA 2328
                      S   QK   PK EDSDDE PL+S+ QLKSN G S  SKS +S+E KP   
Sbjct: 161  SSHANKVLGTSASVQKSKPPKKEDSDDEIPLASRFQLKSNAGAS-TSKSSNSEEVKP--- 216

Query: 2327 KNNQNGSALRDSSSKKPSTMLSKRPASEIKSAGQSSVKKHKLSNASVPINNKQASVKAEP 2148
            K  QNG           +T+LSKRP  ++    +  +K               ASVK E 
Sbjct: 217  KIRQNGLP--------STTVLSKRPPGDVSLLLRLQLKSLGFLMHLHLFRLSXASVKPEK 268

Query: 2147 KVEDDDDHVPISQRMKKPATADKKSSAVKNVTXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1968
            K EDDDD VPISQR+KK   +  K S+ K  T                            
Sbjct: 269  KTEDDDDDVPISQRIKKSVASASKVSSTKKATKVVSSSMKTKKKLKKSKYSKSSKLQ--- 325

Query: 1967 VPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQEEVATMFAVMLDTEY 1788
              P SGEGQKWTTL+HNGVIFPP Y+PHGVK+LYKGKP+NLTPEQEEVATM+AVMLDTEY
Sbjct: 326  --PSSGEGQKWTTLVHNGVIFPPSYKPHGVKMLYKGKPINLTPEQEEVATMYAVMLDTEY 383

Query: 1787 MSKPKFKENFMSDWRKILGKNHIIQNLEDCDFTPIYEWHQXXXXXXXXXXXXXXXXXXXX 1608
            MSKP+FKENFM+DWRKILGKNH+IQNL+DCDFTPIYEWHQ                    
Sbjct: 384  MSKPQFKENFMNDWRKILGKNHVIQNLDDCDFTPIYEWHQSEKEKKKQMSTEEKKALREE 443

Query: 1607 XXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDA 1428
                  KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRP+DITINIGK A
Sbjct: 444  KLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPNDITINIGKGA 503

Query: 1427 PIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKSR 1248
            PIPECPIPGERWKE+RHDNTVTWLAFWNDPINP+EFKYVFLAASS+LKGQSDKEKYEK+R
Sbjct: 504  PIPECPIPGERWKEVRHDNTVTWLAFWNDPINPREFKYVFLAASSSLKGQSDKEKYEKAR 563

Query: 1247 LLKDYIQGIRAAYTKDFASKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 1068
             LKDYI+GIR+AYTKDF SKD  K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV
Sbjct: 564  RLKDYIEGIRSAYTKDFTSKDPVKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 623

Query: 1067 ENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKKAGDDIFDKLDTSKLN 888
            ENVEP+PPNILKFDFLGKDSIRYQNEV V   VFKAIQ FRSGKK GDD+FDKLDTSKLN
Sbjct: 624  ENVEPVPPNILKFDFLGKDSIRYQNEVAVYEPVFKAIQLFRSGKKGGDDLFDKLDTSKLN 683

Query: 887  AHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQHANKEVAIICNHQRT 708
            AHLKELMPGLTAKVFRTYNAS+TL++ L++ T+GG++AE V VY  ANKEVAIICNHQR+
Sbjct: 684  AHLKELMPGLTAKVFRTYNASVTLEQQLTKLTQGGELAEKVAVYNLANKEVAIICNHQRS 743

Query: 707  VSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADGKPKRNLNPEALEKKI 528
            VSKSHS Q+ +LNEKI+ELK +LEE   DL+RAKKGKPPLK ADGK KRNL PEAL+KK+
Sbjct: 744  VSKSHSVQISKLNEKIDELKALLEEFKVDLARAKKGKPPLKGADGKAKRNLAPEALQKKM 803

Query: 527  SQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAK 348
             QTNAKIE +E+  ETKE+LKTVALGTSKINYLDPRITVAWCKRHEVPIEK+FNKSLLAK
Sbjct: 804  DQTNAKIENIEKQIETKEELKTVALGTSKINYLDPRITVAWCKRHEVPIEKMFNKSLLAK 863

Query: 347  FTWAMDVDPSFRF 309
            F WAMDV+PSF F
Sbjct: 864  FAWAMDVEPSFTF 876


>ref|XP_010266803.1| PREDICTED: DNA topoisomerase 1-like [Nelumbo nucifera]
          Length = 890

 Score = 1071 bits (2770), Expect = 0.0
 Identities = 567/858 (66%), Positives = 642/858 (74%), Gaps = 10/858 (1%)
 Frame = -3

Query: 2852 KHDRQLGRPMPDVRSQNGKSSVVQKGKMAFSSKSPPVKSPLRSPEASNSSAKAYPLRPPE 2673
            K D   G+ + D  S NG++S +QKGK   SSK+   KS   S +AS S        P +
Sbjct: 48   KRDGSSGKCVSDSFSPNGQNSSLQKGKAVQSSKASTGKSTETSSKASTSITDKLKCSPQK 107

Query: 2672 ANLRPSAAYRSDNVNRPMKVGKPSIGSATEP-NDSDDSEDDKPLSARLSTGLXXXXXXXX 2496
             +         DN+ + +K  KP      EP  DS DS+DDKPLS RL T          
Sbjct: 108  NS-------SIDNMEKQLK--KP----CNEPYTDSVDSDDDKPLSIRLPTSASLLKCKSS 154

Query: 2495 XXXXXXSR------LGQKPSIPKL---EDSDDEKPLSSKVQLKSNVGTSYASKSYDSDED 2343
                  S         +K ++      EDS+DE PLS K++LK +VG S   K YDS E+
Sbjct: 155  PVSKGLSSPVASSSQSEKTNVTNKKSSEDSEDELPLSLKLKLKPSVGLS-GKKFYDSGEE 213

Query: 2342 KPLVAKNNQNGSALRDSSSKKPSTMLSKRPASEIKSAGQSSVKKHKLSNASVPINNKQAS 2163
            KPLV+K  QNGS+ RD+   K    L+KRP S   S+GQS VKK K+S  SVP   KQ S
Sbjct: 214  KPLVSKLQQNGSSKRDNEPLKSPKNLNKRPLSGANSSGQSLVKKLKVSEVSVPTKVKQTS 273

Query: 2162 VKAEPKVEDDDDHVPISQRMKKPATADKKSSAVKNVTXXXXXXXXXXXXXXXXXXXXXXX 1983
            +K+EPK ED+DD +PISQR+KK A++D KS ++K  T                       
Sbjct: 274  IKSEPKEEDEDD-IPISQRLKKSASSDDKSLSLKKTTKVVSSSFKKTTNKLKKAAKNSKY 332

Query: 1982 XXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQEEVATMFAVM 1803
                 +PP SGEGQKWTTL HNGVIFPP Y+PHGVK+LY GKPV+LTPEQEEVATMFAVM
Sbjct: 333  SKSTKMPPSSGEGQKWTTLEHNGVIFPPLYKPHGVKMLYNGKPVDLTPEQEEVATMFAVM 392

Query: 1802 LDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFTPIYEWHQXXXXXXXXXXXXXXX 1623
             DT+Y +K +F ENFM+DWR ILGKNH+I+  E CDFTPIYEWHQ               
Sbjct: 393  KDTDYATKSRFIENFMNDWRTILGKNHVIKKFELCDFTPIYEWHQREKEKKKQMSAEEKK 452

Query: 1622 XXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITIN 1443
                       KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RI PSDITIN
Sbjct: 453  ALKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITIN 512

Query: 1442 IGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGQSDKEK 1263
            IGK APIPECPIPGERWKE+RHDNTVTWLAFWNDPINPKEFKYVFLAASS+LKGQSDKEK
Sbjct: 513  IGKGAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEK 572

Query: 1262 YEKSRLLKDYIQGIRAAYTKDFASKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGC 1083
            YEK+RLLKDYI+ IRA YT+DF SKD+TK+QIAVATYLIDKLALRAGNEKDDDEADTVGC
Sbjct: 573  YEKARLLKDYIKDIRANYTRDFVSKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGC 632

Query: 1082 CTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKKAGDDIFDKLD 903
            CTLKVENVE +PPN L+FDFLGKDSIRY N VEVE AV+KAI QF++GK+ G+D+FD LD
Sbjct: 633  CTLKVENVELVPPNKLQFDFLGKDSIRYFNTVEVELAVYKAIGQFKNGKEDGEDLFDSLD 692

Query: 902  TSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQHANKEVAIIC 723
            TSKLNAHLKELMPGLTAKVFRTYNASITLDEML+RE+KGGDVAE + VYQHANKEVAIIC
Sbjct: 693  TSKLNAHLKELMPGLTAKVFRTYNASITLDEMLNRESKGGDVAEKIAVYQHANKEVAIIC 752

Query: 722  NHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADGKPKRNLNPEA 543
            NHQR+VSKSHSAQM RL++KI+ELK  L+EL TDL+RAKKGKPPLK ADGKPKRNL PEA
Sbjct: 753  NHQRSVSKSHSAQMHRLDDKIKELKDALDELKTDLARAKKGKPPLKGADGKPKRNLTPEA 812

Query: 542  LEKKISQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNK 363
            LEKKI+Q NAKIEKMERDK+ KEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIEKIFNK
Sbjct: 813  LEKKIAQANAKIEKMERDKQIKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNK 872

Query: 362  SLLAKFTWAMDVDPSFRF 309
            SLLAKF WAMDVDP FRF
Sbjct: 873  SLLAKFAWAMDVDPDFRF 890


>ref|XP_009619726.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 1-like [Nicotiana
            tomentosiformis]
          Length = 877

 Score = 1070 bits (2767), Expect = 0.0
 Identities = 565/853 (66%), Positives = 635/853 (74%), Gaps = 5/853 (0%)
 Frame = -3

Query: 2852 KHDRQLGRPMPDVRSQNGKSSVVQKGKMAFSSKSPPVKSPLRSPEASNSSAKAYPLRPPE 2673
            K D + GR   DVRS NG+SS  QK K   SSK+    SP  SP+AS SS +  P   P 
Sbjct: 44   KQDGRSGRQASDVRSPNGQSSSAQKVKAGTSSKASRAVSPFTSPKASPSSGRTSPA--PN 101

Query: 2672 ANLRPSAAYRSDNVNRPMKV----GKPSIGSATEPND-SDDSEDDKPLSARLSTGLXXXX 2508
            +    SA  ++ +VN+  K+     K ++   +EPND ++DSEDDKPLSARLS+GL    
Sbjct: 102  SRPSASAGNQAKDVNQQSKIVPNEPKQAVEPKSEPNDEAEDSEDDKPLSARLSSGLSKSN 161

Query: 2507 XXXXXXXXXXSRLGQKPSIPKLEDSDDEKPLSSKVQLKSNVGTSYASKSYDSDEDKPLVA 2328
                      S   QK   PK EDSDDE PL+S+ QLKSN G S  SKS +S+E KP   
Sbjct: 162  SSHANKVLGTSASVQKSRPPKKEDSDDEIPLASRFQLKSNAGAS-TSKSSNSEEVKP--- 217

Query: 2327 KNNQNGSALRDSSSKKPSTMLSKRPASEIKSAGQSSVKKHKLSNASVPINNKQASVKAEP 2148
            K  QNG           +T+LSKRP  ++    +  +K               ASVK E 
Sbjct: 218  KIRQNGLP--------STTVLSKRPPGDVSLLLRLQLKSLGFLMHLHLFRVSXASVKPEK 269

Query: 2147 KVEDDDDHVPISQRMKKPATADKKSSAVKNVTXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1968
            K EDDDD VPISQR+KK   +  K S+ K  T                            
Sbjct: 270  KTEDDDDDVPISQRIKKSVASASKLSSAKKATKVVSSSMKTKKKLKKSKYSKSSKLQ--- 326

Query: 1967 VPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQEEVATMFAVMLDTEY 1788
              P SGEGQKWTTL+HNGVIFPPPY+PHGVK+LYKGKPV+LTPEQEEVATM+AVMLDT+Y
Sbjct: 327  --PSSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLDTDY 384

Query: 1787 MSKPKFKENFMSDWRKILGKNHIIQNLEDCDFTPIYEWHQXXXXXXXXXXXXXXXXXXXX 1608
            MSK +FKENFM+DWRKILGKNH+IQNL+DCDFTPIYEWHQ                    
Sbjct: 385  MSKLQFKENFMNDWRKILGKNHVIQNLDDCDFTPIYEWHQSEKEKKKQMSTEEKKALREE 444

Query: 1607 XXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDA 1428
                  KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRP+DITINIGK A
Sbjct: 445  KLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPNDITINIGKGA 504

Query: 1427 PIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKSR 1248
            PIPECPIPGERWKE+RHDNTVTWLAFWNDPINP+EFKYVFLAASS+LKGQSDKEKYEK+R
Sbjct: 505  PIPECPIPGERWKEVRHDNTVTWLAFWNDPINPREFKYVFLAASSSLKGQSDKEKYEKAR 564

Query: 1247 LLKDYIQGIRAAYTKDFASKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 1068
             LKDYI+GIR+AYTKDF SKD  K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV
Sbjct: 565  RLKDYIEGIRSAYTKDFTSKDPVKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 624

Query: 1067 ENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKKAGDDIFDKLDTSKLN 888
            ENVEP+PPNILKFDFLGKDSIRYQNEV V   VFKAIQ FRSGKK GDD+FDKLDTSKLN
Sbjct: 625  ENVEPVPPNILKFDFLGKDSIRYQNEVAVYEPVFKAIQLFRSGKKGGDDLFDKLDTSKLN 684

Query: 887  AHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQHANKEVAIICNHQRT 708
            AHLKELMPGLTAKVFRTYNAS+TL++ L++ T+GG++AE V VY  ANKEVAIICNHQR+
Sbjct: 685  AHLKELMPGLTAKVFRTYNASVTLEQQLTKLTQGGELAEKVAVYNLANKEVAIICNHQRS 744

Query: 707  VSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADGKPKRNLNPEALEKKI 528
            VSKSHS Q+ +LNEKI+ELK +LEE   DL+RAKKGKPPLK ADGK KRNL PEAL+KKI
Sbjct: 745  VSKSHSVQISKLNEKIDELKALLEEFKVDLARAKKGKPPLKGADGKAKRNLAPEALQKKI 804

Query: 527  SQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAK 348
             QTN KIE +ER  ETKE+LKTVALGTSKINYLDPRITVAWCKRHEVPIEK+FNKSLLAK
Sbjct: 805  DQTNVKIENIERQIETKEELKTVALGTSKINYLDPRITVAWCKRHEVPIEKMFNKSLLAK 864

Query: 347  FTWAMDVDPSFRF 309
            F WAMDV+PSF F
Sbjct: 865  FAWAMDVEPSFTF 877