BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Ephedra29_contig00004194
         (2536 letters)

Database: ./nr 
           115,041,592 sequences; 42,171,959,267 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AEX13478.1 hypothetical protein UMN_4616_01, partial [Pinus radi...   183   3e-50
AEX13477.1 hypothetical protein UMN_4616_01, partial [Pinus taeda]    179   7e-49
AEX13476.1 hypothetical protein UMN_4616_01, partial [Pinus taeda]    176   8e-48
OAE35386.1 hypothetical protein AXG93_2587s1010 [Marchantia poly...   145   3e-33
4HQD_A Chain A, Crystal Structure Of Engineered Protein. Northea...   108   1e-23
4GPM_A Chain A, Crystal Structure Of Engineered Protein. Northea...   103   7e-22
4HB5_A Chain A, Crystal Structure Of Engineered Protein. Northea...   103   9e-22
5EIL_A Chain A, Computational Design Of A High-affinity Metallop...    96   3e-19
4GMR_A Chain A, Crystal Structure Of Engineered Protein. Northea...    94   2e-18
4ATZ_D Chain D, Ad5 Knob In Complex With A Designed Ankyrin Repe...    93   2e-18
4HLL_A Chain A, Crystal Structure Of Artificial Ankyrin Repeat P...    94   2e-18
2V5Q_C Chain C, Crystal Structure Of Wild-type Plk-1 Kinase Doma...    93   3e-18
3NOC_D Chain D, Designed Ankyrin Repeat Protein (Darpin) Binders...    93   4e-18
AFI09265.1 LmrCD-specific DARPin, partial [synthetic construct]        92   1e-17
4K5A_B Chain B, Co-crystallization With Conformation-specific De...    91   1e-17
AAO25692.1 ankyrin repeat protein E4_8, partial [synthetic const...    92   2e-17
4F6R_D Chain D, Tubulin:stathmin-Like Domain Complex 4HNA_D Chai...    91   2e-17
1SVX_A Chain A, Crystal Structure Of A Designed Selected Ankyrin...    90   3e-17
CAQ52955.1 CD4-specific ankyrin repeat protein D27.2 [synthetic ...    90   3e-17
4DUI_A Chain A, Darpin D1 Binding To Tubulin Beta Chain (not In ...    90   5e-17

>AEX13478.1 hypothetical protein UMN_4616_01, partial [Pinus radiata]
          Length = 147

 Score =  183 bits (464), Expect = 3e-50
 Identities = 85/137 (62%), Positives = 110/137 (80%)
 Frame = +3

Query: 1113 AVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNTTRRMIDAKDK 1292
            AVR N+   ++KL+ GG  IQS D++GRT LHWATVLGHE+ALK LLLNT+R++ID KDK
Sbjct: 10   AVRSNDAGMIKKLLEGGNPIQSSDSIGRTPLHWATVLGHEKALKALLLNTSRQIIDTKDK 69

Query: 1293 HGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEVVDLLIENGAD 1472
             GRT LHY C+ G  QFAS++IKRGAS  S D +GRTPLHYA Q++  ++V+LL+ NGA+
Sbjct: 70   LGRTPLHYGCAGGRTQFASILIKRGASVNSKDSKGRTPLHYAAQNVKVDMVELLLNNGAN 129

Query: 1473 KNVGDCDGVASWDMALQ 1523
            K+VGDC+GV  WD+AL+
Sbjct: 130  KDVGDCNGVRPWDLALK 146


>AEX13477.1 hypothetical protein UMN_4616_01, partial [Pinus taeda]
          Length = 147

 Score =  179 bits (454), Expect = 7e-49
 Identities = 83/137 (60%), Positives = 111/137 (81%)
 Frame = +3

Query: 1113 AVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNTTRRMIDAKDK 1292
            AVR N++  ++KLIAGG  IQS D++G+T LHWATVLGH+EALK LLLNT++++ID KDK
Sbjct: 10   AVRSNDVGVIKKLIAGGNLIQSSDSIGQTPLHWATVLGHDEALKALLLNTSKQLIDVKDK 69

Query: 1293 HGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEVVDLLIENGAD 1472
             GRT LHYAC+ G  Q AS +IKRGA   S+D +GRTPLHYA Q++  ++V+LL++NGA+
Sbjct: 70   LGRTSLHYACAEGRTQLASNLIKRGAPVNSMDSKGRTPLHYATQNVKVDMVELLLKNGAE 129

Query: 1473 KNVGDCDGVASWDMALQ 1523
            K+V DC+GV  WD+AL+
Sbjct: 130  KDVRDCNGVGPWDLALK 146


>AEX13476.1 hypothetical protein UMN_4616_01, partial [Pinus taeda]
          Length = 147

 Score =  176 bits (446), Expect = 8e-48
 Identities = 81/137 (59%), Positives = 110/137 (80%)
 Frame = +3

Query: 1113 AVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNTTRRMIDAKDK 1292
            AV+ N++  ++ LIAGG  IQS D++G+T LHWATVLGH+EALK LLLNT++++ID KDK
Sbjct: 10   AVKSNDVGVIKNLIAGGNLIQSSDSIGQTPLHWATVLGHDEALKALLLNTSKQLIDVKDK 69

Query: 1293 HGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEVVDLLIENGAD 1472
             GRT LHYAC+ G  Q AS +IKRGA   S+D +GRTPLHYA Q++  ++V+LL++NGA+
Sbjct: 70   LGRTSLHYACAEGRTQLASNLIKRGAPVNSMDSKGRTPLHYATQNVKVDMVELLLKNGAE 129

Query: 1473 KNVGDCDGVASWDMALQ 1523
            K+V DC+GV  WD+AL+
Sbjct: 130  KDVKDCNGVGPWDLALK 146


>OAE35386.1 hypothetical protein AXG93_2587s1010 [Marchantia polymorpha subsp.
            polymorpha]
          Length = 499

 Score =  145 bits (366), Expect = 3e-33
 Identities = 97/279 (34%), Positives = 134/279 (48%), Gaps = 19/279 (6%)
 Frame = +3

Query: 1113 AVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNTTRRMIDAKDK 1292
            AV+ N++  +RKLI  G  + S D  GR+ LHWA V GH+EA K L+LNT++R +D+ D 
Sbjct: 39   AVKENDVTTIRKLIERGAKVNSPDRFGRSPLHWAIVYGHQEATKALILNTSKRALDSTDS 98

Query: 1293 HGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEVVDLLIENGAD 1472
             G T LHYA   G  +   ++I RGA     D R RTPLH+A Q   P +V++LI  GAD
Sbjct: 99   CGCTALHYAALGGRTEIGRILIDRGAQVNCADSRQRTPLHFAAQHPQPTMVEMLISRGAD 158

Query: 1473 KNVGD------CDGVASWDMALQLGCSHLFGALKSHHAVRVENNEETEQSQAKKHHIKNA 1634
            K   D      CD    W     L C              +  +   +  + K H ++  
Sbjct: 159  KRCRDFREYLPCDVALEWASFSSLAC--------------LRPDAPKKDPKLKVHPVEIV 204

Query: 1635 ENDYLQAKKHHPIKNEGLQGKQYGSLDALLADWKRA--EAKKKEEPHDPV--------KD 1784
            +    +A     ++ +G       SLD LL  WK A  EA++K+E    V        + 
Sbjct: 205  DCPDARAAAVDVVQRKG------PSLDKLLESWKSAETEARRKKEAESQVAARSFADLQQ 258

Query: 1785 ALNVWREAEAVARQERKMHS--PNSCED-GNDTFCQSSS 1892
             L  WR AE  ARQ  +  S  P+  +D GND F  S S
Sbjct: 259  RLQEWRAAELDARQAHRADSSRPSFVDDWGNDAFSSSPS 297


>4HQD_A Chain A, Crystal Structure Of Engineered Protein. Northeast
            Structural Genomics Consortium Target Or265. 4HQD_B Chain
            B, Crystal Structure Of Engineered Protein. Northeast
            Structural Genomics Consortium Target Or265.
          Length = 169

 Score =  108 bits (270), Expect = 1e-23
 Identities = 62/168 (36%), Positives = 87/168 (51%), Gaps = 7/168 (4%)
 Frame = +3

Query: 1083 MDNCAPGLLRAVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNT 1262
            M      L+ A      D+++ LI  G  + + D+ GRT LH+A   GH+E +K+L+   
Sbjct: 1    MSELGKRLIEAAENGNKDRVKDLIENGADVNASDSDGRTPLHYAAKEGHKEIVKLLISKG 60

Query: 1263 TRRMIDAKDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEV 1442
                ++AKD  GRT LHYA   G+ +   L+I +GA   + D  GRTPLHYA +    E+
Sbjct: 61   AD--VNAKDSDGRTPLHYAAKEGHKEIVKLLISKGADVNAKDSDGRTPLHYAAKEGHKEI 118

Query: 1443 VDLLIENGADKNVGDCDGVASWDMALQLGCSHLF-------GALKSHH 1565
            V LLI  GAD N  D DG    D+A + G   +        G L+ HH
Sbjct: 119  VKLLISKGADVNTSDSDGRTPLDLAREHGNEEIVKLLEKQGGWLEHHH 166


>4GPM_A Chain A, Crystal Structure Of Engineered Protein. Northeast
            Structural Genomics Consortium Target Or264. 4GPM_B Chain
            B, Crystal Structure Of Engineered Protein. Northeast
            Structural Genomics Consortium Target Or264.
          Length = 169

 Score =  103 bits (257), Expect = 7e-22
 Identities = 61/168 (36%), Positives = 87/168 (51%), Gaps = 7/168 (4%)
 Frame = +3

Query: 1083 MDNCAPGLLRAVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNT 1262
            M      L+ A      D+++ LI  G  + + D+ GRT LH A   GH+E +K+L+   
Sbjct: 1    MSELGKRLIEAAENGNKDRVKDLIENGADVNASDSDGRTPLHHAAENGHKEVVKLLISKG 60

Query: 1263 TRRMIDAKDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEV 1442
                ++AKD  GRT LH+A   G+ +   L+I +GA   + D  GRTPLH+A ++   EV
Sbjct: 61   AD--VNAKDSDGRTPLHHAAENGHKEVVKLLISKGADVNAKDSDGRTPLHHAAENGHKEV 118

Query: 1443 VDLLIENGADKNVGDCDGVASWDMALQLGCSHLF-------GALKSHH 1565
            V LLI  GAD N  D DG    D+A + G   +        G L+ HH
Sbjct: 119  VKLLISKGADVNTSDSDGRTPLDLAREHGNEEVVKLLEKQGGWLEHHH 166


>4HB5_A Chain A, Crystal Structure Of Engineered Protein. Northeast
            Structural Genomics Consortium Target Or267. 4HB5_B Chain
            B, Crystal Structure Of Engineered Protein. Northeast
            Structural Genomics Consortium Target Or267.
          Length = 169

 Score =  103 bits (256), Expect = 9e-22
 Identities = 60/168 (35%), Positives = 86/168 (51%), Gaps = 7/168 (4%)
 Frame = +3

Query: 1083 MDNCAPGLLRAVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNT 1262
            M      L+ A      D+++ L+  G    + D+ GRT LH+A   GH+E +K+LL   
Sbjct: 1    MSELGKRLIEAAENGNKDRVKDLLENGADPNASDSDGRTPLHYAAENGHKEIVKLLLSKG 60

Query: 1263 TRRMIDAKDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEV 1442
                 +AKD  GRT LHYA   G+ +   L++ +GA   + D  GRTPLHYA ++   E+
Sbjct: 61   ADP--NAKDSDGRTPLHYAAENGHKEIVKLLLSKGADPNAKDSDGRTPLHYAAENGHKEI 118

Query: 1443 VDLLIENGADKNVGDCDGVASWDMALQLGCSHLF-------GALKSHH 1565
            V LL+  GAD N  D DG    D+A + G   +        G L+ HH
Sbjct: 119  VKLLLSKGADPNTSDSDGRTPLDLAREHGNEEIVKLLEKQGGWLEHHH 166



 Score = 73.6 bits (179), Expect = 2e-11
 Identities = 43/115 (37%), Positives = 60/115 (52%)
 Frame = +3

Query: 1224 GHEEALKVLLLNTTRRMIDAKDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRT 1403
            G+++ +K LL N      +A D  GRT LHYA   G+ +   L++ +GA   + D  GRT
Sbjct: 15   GNKDRVKDLLENGADP--NASDSDGRTPLHYAAENGHKEIVKLLLSKGADPNAKDSDGRT 72

Query: 1404 PLHYAVQSMSPEVVDLLIENGADKNVGDCDGVASWDMALQLGCSHLFGALKSHHA 1568
            PLHYA ++   E+V LL+  GAD N  D DG      A + G   +   L S  A
Sbjct: 73   PLHYAAENGHKEIVKLLLSKGADPNAKDSDGRTPLHYAAENGHKEIVKLLLSKGA 127


>5EIL_A Chain A, Computational Design Of A High-affinity Metalloprotein
            Homotrimer Containing A Metal Chelating Non-canonical
            Amino Acid 5EIL_B Chain B, Computational Design Of A
            High-affinity Metalloprotein Homotrimer Containing A
            Metal Chelating Non-canonical Amino Acid 5EIL_C Chain C,
            Computational Design Of A High-affinity Metalloprotein
            Homotrimer Containing A Metal Chelating Non-canonical
            Amino Acid
          Length = 159

 Score = 95.5 bits (236), Expect = 3e-19
 Identities = 54/142 (38%), Positives = 78/142 (54%)
 Frame = +3

Query: 1104 LLRAVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNTTRRMIDA 1283
            L+ AV +   + ++ L+  G    + D  G T LH A + GH+E +K+LL        +A
Sbjct: 8    LIXAVLIGSKEAVKVLLDLGADPNASDEDGLTPLHAAAMAGHKEIVKLLLSKGADP--NA 65

Query: 1284 KDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEVVDLLIEN 1463
            KD  GRT LHYA   G+ +   L++ +GA   + D  GRTPLHYA ++   E+V LL+  
Sbjct: 66   KDSDGRTPLHYAAENGHKEIVKLLLSKGADPNAKDSDGRTPLHYAAENGHKEIVKLLLSK 125

Query: 1464 GADKNVGDCDGVASWDMALQLG 1529
            GAD N  D DG    D+A + G
Sbjct: 126  GADPNTSDSDGRTPLDLAREHG 147



 Score = 74.3 bits (181), Expect = 8e-12
 Identities = 45/119 (37%), Positives = 63/119 (52%)
 Frame = +3

Query: 1212 ATVLGHEEALKVLLLNTTRRMIDAKDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDC 1391
            A ++G +EA+KVLL        +A D+ G T LH A  AG+ +   L++ +GA   + D 
Sbjct: 11   AVLIGSKEAVKVLL--DLGADPNASDEDGLTPLHAAAMAGHKEIVKLLLSKGADPNAKDS 68

Query: 1392 RGRTPLHYAVQSMSPEVVDLLIENGADKNVGDCDGVASWDMALQLGCSHLFGALKSHHA 1568
             GRTPLHYA ++   E+V LL+  GAD N  D DG      A + G   +   L S  A
Sbjct: 69   DGRTPLHYAAENGHKEIVKLLLSKGADPNAKDSDGRTPLHYAAENGHKEIVKLLLSKGA 127



 Score = 71.6 bits (174), Expect = 7e-11
 Identities = 46/129 (35%), Positives = 68/129 (52%)
 Frame = +3

Query: 1080 DMDNCAPGLLRAVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLN 1259
            D D   P L  A      + ++ L++ G    + D+ GRT LH+A   GH+E +K+LL  
Sbjct: 34   DEDGLTP-LHAAAMAGHKEIVKLLLSKGADPNAKDSDGRTPLHYAAENGHKEIVKLLLSK 92

Query: 1260 TTRRMIDAKDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPE 1439
                  +AKD  GRT LHYA   G+ +   L++ +GA   + D  GRTPL  A +  + E
Sbjct: 93   GADP--NAKDSDGRTPLHYAAENGHKEIVKLLLSKGADPNTSDSDGRTPLDLAREHGNEE 150

Query: 1440 VVDLLIENG 1466
            +V LL + G
Sbjct: 151  IVKLLEKQG 159


>4GMR_A Chain A, Crystal Structure Of Engineered Protein. Northeast
            Structural Genomics Consortium Target Or266. 4GMR_B Chain
            B, Crystal Structure Of Engineered Protein. Northeast
            Structural Genomics Consortium Target Or266.
          Length = 169

 Score = 94.0 bits (232), Expect = 2e-18
 Identities = 56/168 (33%), Positives = 84/168 (50%), Gaps = 7/168 (4%)
 Frame = +3

Query: 1083 MDNCAPGLLRAVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNT 1262
            M      L+ A      D+++ L+  G  + + D+ G+T LH A   GH+E +K+LL   
Sbjct: 1    MSELGKRLIEAAENGNKDRVKDLLENGADVNASDSDGKTPLHLAAENGHKEVVKLLLSQG 60

Query: 1263 TRRMIDAKDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEV 1442
                 +AKD  G+T LH A   G+ +   L++ +GA   + D  G+TPLH A ++   EV
Sbjct: 61   ADP--NAKDSDGKTPLHLAAENGHKEVVKLLLSQGADPNAKDSDGKTPLHLAAENGHKEV 118

Query: 1443 VDLLIENGADKNVGDCDGVASWDMALQLGCSHLF-------GALKSHH 1565
            V LL+  GAD N  D DG    D+A + G   +        G L+ HH
Sbjct: 119  VKLLLSQGADPNTSDSDGRTPLDLAREHGNEEVVKLLEKQGGWLEHHH 166



 Score = 68.2 bits (165), Expect = 1e-09
 Identities = 40/115 (34%), Positives = 60/115 (52%)
 Frame = +3

Query: 1224 GHEEALKVLLLNTTRRMIDAKDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRT 1403
            G+++ +K LL N     ++A D  G+T LH A   G+ +   L++ +GA   + D  G+T
Sbjct: 15   GNKDRVKDLLENGAD--VNASDSDGKTPLHLAAENGHKEVVKLLLSQGADPNAKDSDGKT 72

Query: 1404 PLHYAVQSMSPEVVDLLIENGADKNVGDCDGVASWDMALQLGCSHLFGALKSHHA 1568
            PLH A ++   EVV LL+  GAD N  D DG     +A + G   +   L S  A
Sbjct: 73   PLHLAAENGHKEVVKLLLSQGADPNAKDSDGKTPLHLAAENGHKEVVKLLLSQGA 127


>4ATZ_D Chain D, Ad5 Knob In Complex With A Designed Ankyrin Repeat Protein
            4ATZ_E Chain E, Ad5 Knob In Complex With A Designed
            Ankyrin Repeat Protein 4ATZ_F Chain F, Ad5 Knob In
            Complex With A Designed Ankyrin Repeat Protein
          Length = 154

 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 52/142 (36%), Positives = 83/142 (58%)
 Frame = +3

Query: 1104 LLRAVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNTTRRMIDA 1283
            LL A R  + D++R L+A G    + D  GRT LH A  +GH E ++VLL N     ++A
Sbjct: 6    LLEAARAGQDDEVRILMANGADANAYDHYGRTPLHMAAAVGHLEIVEVLLRNGAD--VNA 63

Query: 1284 KDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEVVDLLIEN 1463
             D +G T LH A S G+++   +++K GA   + D  G TPL+ A      E+V++L+++
Sbjct: 64   VDTNGTTPLHLAASLGHLEIVEVLLKYGADVNAKDATGITPLYLAAYWGHLEIVEVLLKH 123

Query: 1464 GADKNVGDCDGVASWDMALQLG 1529
            GAD N  D  G  ++D+++ +G
Sbjct: 124  GADVNAQDKFGKTAFDISIDIG 145



 Score = 69.7 bits (169), Expect = 3e-10
 Identities = 40/127 (31%), Positives = 66/127 (51%)
 Frame = +3

Query: 1188 LGRTALHWATVLGHEEALKVLLLNTTRRMIDAKDKHGRTCLHYACSAGNVQFASLMIKRG 1367
            LG+  L  A   G ++ +++L+ N      +A D +GRT LH A + G+++   ++++ G
Sbjct: 2    LGKKLLEAARA-GQDDEVRILMANGADA--NAYDHYGRTPLHMAAAVGHLEIVEVLLRNG 58

Query: 1368 ASAKSVDCRGRTPLHYAVQSMSPEVVDLLIENGADKNVGDCDGVASWDMALQLGCSHLFG 1547
            A   +VD  G TPLH A      E+V++L++ GAD N  D  G+    +A   G   +  
Sbjct: 59   ADVNAVDTNGTTPLHLAASLGHLEIVEVLLKYGADVNAKDATGITPLYLAAYWGHLEIVE 118

Query: 1548 ALKSHHA 1568
             L  H A
Sbjct: 119  VLLKHGA 125


>4HLL_A Chain A, Crystal Structure Of Artificial Ankyrin Repeat
            Protein_ank(gag)1d4
          Length = 173

 Score = 93.6 bits (231), Expect = 2e-18
 Identities = 53/152 (34%), Positives = 86/152 (56%)
 Frame = +3

Query: 1104 LLRAVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNTTRRMIDA 1283
            LL A R  + D++R L+  G  + + D++G T LH A   GH E +++LL +     ++A
Sbjct: 21   LLEAARAGQDDEVRLLLEHGADVNARDSIGSTPLHLAAYYGHLEIVRLLLEHGAD--VNA 78

Query: 1284 KDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEVVDLLIEN 1463
            +D  G T LHYA   G+++   L+++ GA   + D  G TPLH A +    E+V LL+++
Sbjct: 79   RDSTGTTPLHYAARLGHLEIVRLLLEHGADVNARDAMGWTPLHLAAKKGHLEIVRLLLKH 138

Query: 1464 GADKNVGDCDGVASWDMALQLGCSHLFGALKS 1559
            GAD N  D  G  ++D+++  G   L   L+S
Sbjct: 139  GADVNANDHFGKTAFDISIDNGNEDLAEILQS 170



 Score = 65.5 bits (158), Expect = 1e-08
 Identities = 42/127 (33%), Positives = 66/127 (51%)
 Frame = +3

Query: 1188 LGRTALHWATVLGHEEALKVLLLNTTRRMIDAKDKHGRTCLHYACSAGNVQFASLMIKRG 1367
            LG+  L  A   G ++ +++LL +     ++A+D  G T LH A   G+++   L+++ G
Sbjct: 17   LGKKLLEAARA-GQDDEVRLLLEHGAD--VNARDSIGSTPLHLAAYYGHLEIVRLLLEHG 73

Query: 1368 ASAKSVDCRGRTPLHYAVQSMSPEVVDLLIENGADKNVGDCDGVASWDMALQLGCSHLFG 1547
            A   + D  G TPLHYA +    E+V LL+E+GAD N  D  G     +A + G   +  
Sbjct: 74   ADVNARDSTGTTPLHYAARLGHLEIVRLLLEHGADVNARDAMGWTPLHLAAKKGHLEIVR 133

Query: 1548 ALKSHHA 1568
             L  H A
Sbjct: 134  LLLKHGA 140


>2V5Q_C Chain C, Crystal Structure Of Wild-type Plk-1 Kinase Domain In
            Complex With A Selective Darpin 2V5Q_D Chain D, Crystal
            Structure Of Wild-type Plk-1 Kinase Domain In Complex
            With A Selective Darpin
          Length = 167

 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 53/142 (37%), Positives = 80/142 (56%)
 Frame = +3

Query: 1104 LLRAVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNTTRRMIDA 1283
            LL A R  + D++R LIA G  + + D  G T LH A V GH E ++VLL +     +DA
Sbjct: 18   LLEAARAGQDDEVRILIANGADVNAVDNTGLTPLHLAAVSGHLEIVEVLLKHGAD--VDA 75

Query: 1284 KDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEVVDLLIEN 1463
             D +G T LH A   G+++   +++K GA   + D  G TPLH A      E+V++L++ 
Sbjct: 76   ADVYGFTPLHLAAMTGHLEIVEVLLKYGADVNAFDMTGSTPLHLAADEGHLEIVEVLLKY 135

Query: 1464 GADKNVGDCDGVASWDMALQLG 1529
            GAD N  D  G  ++D+++  G
Sbjct: 136  GADVNAQDKFGKTAFDISIDNG 157


>3NOC_D Chain D, Designed Ankyrin Repeat Protein (Darpin) Binders To Acrb:
            Plasticity Of The Interface 3NOC_E Chain E, Designed
            Ankyrin Repeat Protein (Darpin) Binders To Acrb:
            Plasticity Of The Interface
          Length = 169

 Score = 92.8 bits (229), Expect = 4e-18
 Identities = 53/142 (37%), Positives = 81/142 (57%)
 Frame = +3

Query: 1104 LLRAVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNTTRRMIDA 1283
            LL A R  + D++R L+A G  + + D  G T LH A   GH E ++VLL N     ++A
Sbjct: 18   LLEAARAGQDDEVRILMANGADVNARDFTGWTPLHLAAHFGHLEIVEVLLKNGAD--VNA 75

Query: 1284 KDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEVVDLLIEN 1463
            KD  G T LH A   G+++   +++K GA   + D  G TPLH A +    E+V++L++N
Sbjct: 76   KDSLGVTPLHLAARRGHLEIVEVLLKNGADVNASDSHGFTPLHLAAKRGHLEIVEVLLKN 135

Query: 1464 GADKNVGDCDGVASWDMALQLG 1529
            GAD N  D  G  ++D+++  G
Sbjct: 136  GADVNAQDKFGKTAFDISIDNG 157



 Score = 62.4 bits (150), Expect = 1e-07
 Identities = 34/114 (29%), Positives = 60/114 (52%)
 Frame = +3

Query: 1113 AVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNTTRRMIDAKDK 1292
            A     L+ +  L+  G  + + D+LG T LH A   GH E ++VLL N     ++A D 
Sbjct: 54   AAHFGHLEIVEVLLKNGADVNAKDSLGVTPLHLAARRGHLEIVEVLLKNGAD--VNASDS 111

Query: 1293 HGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEVVDLL 1454
            HG T LH A   G+++   +++K GA   + D  G+T    ++ + + ++ ++L
Sbjct: 112  HGFTPLHLAAKRGHLEIVEVLLKNGADVNAQDKFGKTAFDISIDNGNEDLAEIL 165


>AFI09265.1 LmrCD-specific DARPin, partial [synthetic construct]
          Length = 169

 Score = 91.7 bits (226), Expect = 1e-17
 Identities = 51/142 (35%), Positives = 80/142 (56%)
 Frame = +3

Query: 1104 LLRAVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNTTRRMIDA 1283
            LL A R+   D++R L+A G  + + D  G T LH A  +GH E ++VLL N     ++A
Sbjct: 18   LLEAARVGRDDEVRILMANGADVNAKDIFGDTPLHLAAWIGHLEIVEVLLKNGAD--VNA 75

Query: 1284 KDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEVVDLLIEN 1463
             D  G T LH A  AG+++   +++K GA   ++D  G TPLH        E+V++L++N
Sbjct: 76   ADIWGNTPLHLAADAGHLEIVEVLLKHGADVNAIDWMGDTPLHLTALWGHLEIVEVLLKN 135

Query: 1464 GADKNVGDCDGVASWDMALQLG 1529
            G D N  D  G  ++D+++  G
Sbjct: 136  GVDVNAQDKFGKTAFDISIDNG 157


>4K5A_B Chain B, Co-crystallization With Conformation-specific Designed
            Ankyrin Repeat Proteins Explains The Conformational
            Flexibility Of Bcl-w
          Length = 169

 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 52/142 (36%), Positives = 81/142 (57%)
 Frame = +3

Query: 1104 LLRAVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNTTRRMIDA 1283
            LL A  + + D++R L+A G  + + D  G T LH A + GH E ++VLL   T   ++A
Sbjct: 18   LLEAANVGQHDEVRILMANGADVNAADKYGDTPLHLAAMNGHLEIVEVLL--KTGADVNA 75

Query: 1284 KDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEVVDLLIEN 1463
             D  GRT LH A   G+++   +++K GA   +    G+TPLH A Q    E+V++L+++
Sbjct: 76   VDFMGRTPLHLAADNGHLEIVEVLLKHGADVNAQAFWGKTPLHLAAQQGHLEIVEVLLKH 135

Query: 1464 GADKNVGDCDGVASWDMALQLG 1529
            GAD N  D  G   +D+A+  G
Sbjct: 136  GADVNAQDKFGKTPFDLAIDNG 157



 Score = 72.4 bits (176), Expect = 5e-11
 Identities = 44/127 (34%), Positives = 69/127 (54%)
 Frame = +3

Query: 1188 LGRTALHWATVLGHEEALKVLLLNTTRRMIDAKDKHGRTCLHYACSAGNVQFASLMIKRG 1367
            LG+  L  A V  H+E +++L+ N     ++A DK+G T LH A   G+++   +++K G
Sbjct: 14   LGKKLLEAANVGQHDE-VRILMANGAD--VNAADKYGDTPLHLAAMNGHLEIVEVLLKTG 70

Query: 1368 ASAKSVDCRGRTPLHYAVQSMSPEVVDLLIENGADKNVGDCDGVASWDMALQLGCSHLFG 1547
            A   +VD  GRTPLH A  +   E+V++L+++GAD N     G     +A Q G   +  
Sbjct: 71   ADVNAVDFMGRTPLHLAADNGHLEIVEVLLKHGADVNAQAFWGKTPLHLAAQQGHLEIVE 130

Query: 1548 ALKSHHA 1568
             L  H A
Sbjct: 131  VLLKHGA 137



 Score = 58.5 bits (140), Expect = 3e-06
 Identities = 32/108 (29%), Positives = 60/108 (55%)
 Frame = +3

Query: 1131 LDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNTTRRMIDAKDKHGRTCL 1310
            L+ +  L+  G  + + D +GRT LH A   GH E ++VLL +     ++A+   G+T L
Sbjct: 60   LEIVEVLLKTGADVNAVDFMGRTPLHLAADNGHLEIVEVLLKHGAD--VNAQAFWGKTPL 117

Query: 1311 HYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEVVDLL 1454
            H A   G+++   +++K GA   + D  G+TP   A+ + + ++ ++L
Sbjct: 118  HLAAQQGHLEIVEVLLKHGADVNAQDKFGKTPFDLAIDNGNEDIAEVL 165


>AAO25692.1 ankyrin repeat protein E4_8, partial [synthetic construct]
          Length = 199

 Score = 92.0 bits (227), Expect = 2e-17
 Identities = 53/142 (37%), Positives = 80/142 (56%)
 Frame = +3

Query: 1104 LLRAVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNTTRRMIDA 1283
            LL A R  + D++R L+A G  + + D  G T LH A  +GH E ++VLL N     ++A
Sbjct: 18   LLEAARAGQDDEVRILMANGADVNARDRDGNTPLHLAADMGHLEIVEVLLKNGAD--VNA 75

Query: 1284 KDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEVVDLLIEN 1463
             D  G T LH A   G+++   +++K GA   ++D  G TPLH A  +   E+V++L++N
Sbjct: 76   DDVTGFTPLHLAAVWGHLEIVEVLLKNGADVNAIDTIGYTPLHLAANNGHLEIVEVLLKN 135

Query: 1464 GADKNVGDCDGVASWDMALQLG 1529
            GAD N  D +GV    +A   G
Sbjct: 136  GADVNAHDTNGVTPLHLAAHEG 157



 Score = 81.6 bits (200), Expect = 6e-14
 Identities = 51/150 (34%), Positives = 79/150 (52%)
 Frame = +3

Query: 1080 DMDNCAPGLLRAVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLN 1259
            D D   P L  A  +  L+ +  L+  G  + + D  G T LH A V GH E ++VLL N
Sbjct: 44   DRDGNTP-LHLAADMGHLEIVEVLLKNGADVNADDVTGFTPLHLAAVWGHLEIVEVLLKN 102

Query: 1260 TTRRMIDAKDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPE 1439
                 ++A D  G T LH A + G+++   +++K GA   + D  G TPLH A      E
Sbjct: 103  GAD--VNAIDTIGYTPLHLAANNGHLEIVEVLLKNGADVNAHDTNGVTPLHLAAHEGHLE 160

Query: 1440 VVDLLIENGADKNVGDCDGVASWDMALQLG 1529
            +V++L++ GAD N  D  G  ++D+++  G
Sbjct: 161  IVEVLLKYGADVNAQDKFGKTAFDISIDNG 190


>4F6R_D Chain D, Tubulin:stathmin-Like Domain Complex 4HNA_D Chain D, Kinesin
            Motor Domain In The Adp-mg-alfx State In Complex With
            Tubulin And A Darpin
          Length = 169

 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 51/142 (35%), Positives = 82/142 (57%)
 Frame = +3

Query: 1104 LLRAVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNTTRRMIDA 1283
            LL A R  + D++R L+A G  + + D  G+T LH A + GH E ++VLL +     ++A
Sbjct: 18   LLEAARAGQDDEVRILMANGADVNAEDDSGKTPLHLAAIKGHLEIVEVLLKHGAD--VNA 75

Query: 1284 KDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEVVDLLIEN 1463
             DK G T LH A   G+++   +++K GA   + D  G TPLH A  +   E+V++L++ 
Sbjct: 76   ADKMGDTPLHLAALYGHLEIVEVLLKNGADVNATDTYGFTPLHLAADAGHLEIVEVLLKY 135

Query: 1464 GADKNVGDCDGVASWDMALQLG 1529
            GAD N  D  G  ++D+++  G
Sbjct: 136  GADVNAQDKFGKTAFDISIDNG 157



 Score = 65.5 bits (158), Expect = 1e-08
 Identities = 37/114 (32%), Positives = 61/114 (53%)
 Frame = +3

Query: 1188 LGRTALHWATVLGHEEALKVLLLNTTRRMIDAKDKHGRTCLHYACSAGNVQFASLMIKRG 1367
            LG+  L  A   G ++ +++L+ N     ++A+D  G+T LH A   G+++   +++K G
Sbjct: 14   LGKKLLEAARA-GQDDEVRILMANGAD--VNAEDDSGKTPLHLAAIKGHLEIVEVLLKHG 70

Query: 1368 ASAKSVDCRGRTPLHYAVQSMSPEVVDLLIENGADKNVGDCDGVASWDMALQLG 1529
            A   + D  G TPLH A      E+V++L++NGAD N  D  G     +A   G
Sbjct: 71   ADVNAADKMGDTPLHLAALYGHLEIVEVLLKNGADVNATDTYGFTPLHLAADAG 124


>1SVX_A Chain A, Crystal Structure Of A Designed Selected Ankyrin Repeat
            Protein In Complex With The Maltose Binding Protein
            AAQ93810.1 ankyrin repeat protein off7 [synthetic
            construct]
          Length = 169

 Score = 90.1 bits (222), Expect = 3e-17
 Identities = 51/142 (35%), Positives = 81/142 (57%)
 Frame = +3

Query: 1104 LLRAVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNTTRRMIDA 1283
            LL A R  + D++R L+A G  + + D  G T LH A   GH E ++VLL +     +DA
Sbjct: 18   LLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGAD--VDA 75

Query: 1284 KDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEVVDLLIEN 1463
             D  G T LH A   G+++   +++K GA   ++D  G TPLH A +    E+V++L+++
Sbjct: 76   SDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKH 135

Query: 1464 GADKNVGDCDGVASWDMALQLG 1529
            GAD N  D  G  ++D+++  G
Sbjct: 136  GADVNAQDKFGKTAFDISIDNG 157



 Score = 70.9 bits (172), Expect = 2e-10
 Identities = 42/127 (33%), Positives = 67/127 (52%)
 Frame = +3

Query: 1188 LGRTALHWATVLGHEEALKVLLLNTTRRMIDAKDKHGRTCLHYACSAGNVQFASLMIKRG 1367
            LGR  L  A   G ++ +++L+ N     ++A D  G T LH A  +G+++   +++K G
Sbjct: 14   LGRKLLEAARA-GQDDEVRILMANGAD--VNAADNTGTTPLHLAAYSGHLEIVEVLLKHG 70

Query: 1368 ASAKSVDCRGRTPLHYAVQSMSPEVVDLLIENGADKNVGDCDGVASWDMALQLGCSHLFG 1547
            A   + D  G TPLH A      E+V++L++NGAD N  D DG+    +A + G   +  
Sbjct: 71   ADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVE 130

Query: 1548 ALKSHHA 1568
             L  H A
Sbjct: 131  VLLKHGA 137


>CAQ52955.1 CD4-specific ankyrin repeat protein D27.2 [synthetic construct]
          Length = 169

 Score = 90.1 bits (222), Expect = 3e-17
 Identities = 52/142 (36%), Positives = 84/142 (59%)
 Frame = +3

Query: 1104 LLRAVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNTTRRMIDA 1283
            LL A R  + D++R L+A G  + + D  GRT+LH A   GH E ++VLL +     ++A
Sbjct: 18   LLEAARAGQDDEVRILMANGADVNAKDDEGRTSLHLAAREGHLEIVEVLLKHGAD--VNA 75

Query: 1284 KDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEVVDLLIEN 1463
            +D +G T LH A + G+++   +++K  A   ++D  G TPLH A      EVV++L++N
Sbjct: 76   QDWYGSTPLHLAAAWGHLEIVEVLLKNVADVNAMDGDGSTPLHLAAHYAHLEVVEVLLKN 135

Query: 1464 GADKNVGDCDGVASWDMALQLG 1529
            GAD N  D  G  ++D+++  G
Sbjct: 136  GADVNAQDKFGKTAFDISIDNG 157



 Score = 66.2 bits (160), Expect = 7e-09
 Identities = 37/103 (35%), Positives = 58/103 (56%)
 Frame = +3

Query: 1188 LGRTALHWATVLGHEEALKVLLLNTTRRMIDAKDKHGRTCLHYACSAGNVQFASLMIKRG 1367
            LG+  L  A   G ++ +++L+ N     ++AKD  GRT LH A   G+++   +++K G
Sbjct: 14   LGKRLLEAARA-GQDDEVRILMANGAD--VNAKDDEGRTSLHLAAREGHLEIVEVLLKHG 70

Query: 1368 ASAKSVDCRGRTPLHYAVQSMSPEVVDLLIENGADKNVGDCDG 1496
            A   + D  G TPLH A      E+V++L++N AD N  D DG
Sbjct: 71   ADVNAQDWYGSTPLHLAAAWGHLEIVEVLLKNVADVNAMDGDG 113


>4DUI_A Chain A, Darpin D1 Binding To Tubulin Beta Chain (not In Complex)
          Length = 169

 Score = 89.7 bits (221), Expect = 5e-17
 Identities = 52/142 (36%), Positives = 81/142 (57%)
 Frame = +3

Query: 1104 LLRAVRLNELDKMRKLIAGGYAIQSCDALGRTALHWATVLGHEEALKVLLLNTTRRMIDA 1283
            LL A R  + D++R L+A G  + + DA G T LH A   GH E ++VLL +     ++A
Sbjct: 18   LLEAARAGQDDEVRILMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGAD--VNA 75

Query: 1284 KDKHGRTCLHYACSAGNVQFASLMIKRGASAKSVDCRGRTPLHYAVQSMSPEVVDLLIEN 1463
             D  G T LH A   G+++   +++K GA   +VD  G TPLH A      E+V++L+++
Sbjct: 76   IDIXGSTPLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLHLAAIMGHLEIVEVLLKH 135

Query: 1464 GADKNVGDCDGVASWDMALQLG 1529
            GAD N  D  G  ++D+++  G
Sbjct: 136  GADVNAQDKFGKTAFDISIDNG 157



 Score = 65.1 bits (157), Expect = 2e-08
 Identities = 39/127 (30%), Positives = 66/127 (51%)
 Frame = +3

Query: 1188 LGRTALHWATVLGHEEALKVLLLNTTRRMIDAKDKHGRTCLHYACSAGNVQFASLMIKRG 1367
            LG+  L  A   G ++ +++L+ N     ++A D  G T LH A + G+++   +++K G
Sbjct: 14   LGKKLLEAARA-GQDDEVRILMANGAD--VNATDASGLTPLHLAATYGHLEIVEVLLKHG 70

Query: 1368 ASAKSVDCRGRTPLHYAVQSMSPEVVDLLIENGADKNVGDCDGVASWDMALQLGCSHLFG 1547
            A   ++D  G TPLH A      E+V++L+++GAD N  D  G     +A  +G   +  
Sbjct: 71   ADVNAIDIXGSTPLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLHLAAIMGHLEIVE 130

Query: 1548 ALKSHHA 1568
             L  H A
Sbjct: 131  VLLKHGA 137