BLASTX nr result
ID: Ephedra28_contig00020808
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Ephedra28_contig00020808
(2246 letters)
Database: ./nr
37,332,560 sequences; 13,225,080,153 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|XP_001438717.1| hypothetical protein [Paramecium tetraurelia... 111 2e-21
ref|XP_001581403.1| viral A-type inclusion protein [Trichomonas ... 110 3e-21
ref|XP_001323236.1| viral A-type inclusion protein [Trichomonas ... 110 3e-21
ref|XP_006819694.1| PREDICTED: nuclear anchorage protein 1-like ... 106 4e-20
ref|XP_002495471.1| ZYRO0B12144p [Zygosaccharomyces rouxii] gi|2... 106 5e-20
ref|XP_005159741.1| PREDICTED: titin isoform X4 [Danio rerio] 105 1e-19
ref|XP_005159740.1| PREDICTED: titin isoform X3 [Danio rerio] 105 1e-19
ref|XP_005159739.1| PREDICTED: titin isoform X2 [Danio rerio] 105 1e-19
ref|XP_005159738.1| PREDICTED: titin isoform X1 [Danio rerio] 105 1e-19
ref|XP_685984.6| PREDICTED: titin isoform X7 [Danio rerio] 105 1e-19
ref|XP_637450.1| zipper-like domain-containing protein [Dictyost... 103 2e-19
gb|AAB70839.1| ZipA [Dictyostelium discoideum] 103 2e-19
ref|XP_001579764.1| viral A-type inclusion protein [Trichomonas ... 103 3e-19
ref|XP_005159743.1| PREDICTED: titin isoform X6 [Danio rerio] 102 9e-19
ref|XP_005159742.1| PREDICTED: titin isoform X5 [Danio rerio] 102 9e-19
ref|XP_001582487.1| viral A-type inclusion protein [Trichomonas ... 102 9e-19
ref|XP_001312904.1| viral A-type inclusion protein [Trichomonas ... 102 9e-19
ref|XP_001318285.1| viral A-type inclusion protein [Trichomonas ... 100 2e-18
gb|EAR89974.2| hypothetical protein TTHERM_00561660 [Tetrahymena... 100 3e-18
gb|EMG48182.1| hypothetical protein G210_1294 [Candida maltosa X... 100 3e-18
>ref|XP_001438717.1| hypothetical protein [Paramecium tetraurelia strain d4-2]
gi|124405889|emb|CAK71320.1| unnamed protein product
[Paramecium tetraurelia]
Length = 2413
Score = 111 bits (277), Expect = 2e-21
Identities = 130/662 (19%), Positives = 283/662 (42%), Gaps = 49/662 (7%)
Frame = -2
Query: 2200 SEDLKETVKNLQ------SDLDIEQ-KLSTDRQSEIYSLSAELERITQSEQMSLK---RL 2051
S+ L ET ++L+ + ++IE+ KL ++ + + L++I Q EQ +LK ++
Sbjct: 1023 SKKLNETSQDLEKLKFDLNQVEIEKGKLFQQQEDSLIQIKDLLQKIEQGEQHNLKLKDQI 1082
Query: 2050 KEAEQTLLEAESERESLKAELEE----------SISVLKQELSSARLQIESLEKELNQAN 1901
++ EQ L + +E + + E+ E + LK + S LQIE EK ++Q N
Sbjct: 1083 EQQEQRLQDNIAELQIKQEEINEMAMKEQASKFELDCLKAKCLSYELQIEDQEKLISQQN 1142
Query: 1900 EEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEV 1721
+ + LS+ + Q+ +L++ +++L +L+ ++Y +D ++ L+E IE K
Sbjct: 1143 NQAQQLSEIQEQLQDLQKNNEELQQNLNDKEQNYDILQNAYYDIGDQKKNLEEEIEDKNQ 1202
Query: 1720 EERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEEST 1541
E S ++ D+ + ++++ + I +L+ ++Q S + + F E
Sbjct: 1203 E---------ISIQNRDLKI--YKEQIDQNKALINQLQEQIAQFRNSANIN---FAEN-- 1246
Query: 1540 KVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHD 1361
C L ++++ +E+ +++ N++E S +K LE + ++ N +++
Sbjct: 1247 -----CKLNEQVQMMKKELESYQI----DSKQNLDERSDKIKDLE--QQIIDLQNELENQ 1295
Query: 1360 TLSSTHQGS-MEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKM 1184
++ S +E+ ++ T +N + Q + EE K KQ E +
Sbjct: 1296 QFQIQYKDSKIEELNNNLQETSENLDDIKQELEITSRQLKNEQAQKEEELKCKQQLEGII 1355
Query: 1183 LQAELN--NWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIEL 1010
Q +L ++ N + L L N ++ +I K + + Q+ E ++E+
Sbjct: 1356 QQQKLEAQQYILTTNQQQENLLSLHNKIIEYCNEIESLKNQI--STLQIECEKQQKEMEV 1413
Query: 1009 VEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIE 830
+ +N +L+ + K +E Q FQ + K + L EK+Q +E
Sbjct: 1414 LNENLNQANTLLEDQ---------KSNLENSEFQINYFQTQSKEIKIQYDQLQEKLQDLE 1464
Query: 829 EREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQ 650
+ ++L S + + + + Q+EIS K+ L + + + +Q I+
Sbjct: 1465 QENEILNRNQSNNAQKQEQIQNEKYILQQEISQLKQSLATLFEERQNNQDRIQELIFTIE 1524
Query: 649 -------------EMLLNQNVNYPLE----ATVNIGFDQSMDEAVSEIAVQTFPNKDTED 521
E++ NQ ++ N + Q+++ +++ KD +
Sbjct: 1525 LQKSEDAKKDQKIELITNQELDLQQRLIELQEQNTTYQQNIESIQNQL-------KDEQL 1577
Query: 520 INTEIAHTSDKDE---------EVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDP 368
I + ++KD+ E+++L Q+ NL+ + L+Q + L+ +
Sbjct: 1578 ITENLKQQNEKDQKQIDELKNIEIVQLNQQIVNLKEKIAFLEQNEIQTSELSSHLENLRQ 1637
Query: 367 EK 362
EK
Sbjct: 1638 EK 1639
Score = 76.6 bits (187), Expect = 4e-11
Identities = 123/666 (18%), Positives = 274/666 (41%), Gaps = 54/666 (8%)
Frame = -2
Query: 2233 VRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKR 2054
V+ +++K K + E+ ++ ++ + S+L + Q+ + EI + LE+ Q ++ ++
Sbjct: 737 VKQELKKLKKLEEEYQQ-LRQINSNLTLAQE---ELNLEIEEKNQLLEQNKQQLEIEQEQ 792
Query: 2053 LKEAEQTLLEAESERESLKA-----ELEESISVLKQELSSARLQIESLEKELNQANEEVK 1889
L+ A + LE + + ++ K +LE I LKQ+ + ++ESL+ + ++++
Sbjct: 793 LQNAIKENLELKQQNQTQKLLEVNKQLELQIEGLKQKEKEQQAKLESLKTQTENQDKKLI 852
Query: 1888 VLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQ 1709
Q+ + E QL++ L DY L+Q+ +K E+ + + E RQ
Sbjct: 853 QNQNLIQQLNDKENSHSQLNSQLQSDVNDY---LKQIQEKSQEVEKFKMDLLSSENRVRQ 909
Query: 1708 RECMLAASERSNDI--------NVNALEKKLSAYEG--------------KIRRLENDVS 1595
+E L A+E N+I N A ++++ + I++L+ D++
Sbjct: 910 QE--LIANELKNEIMLLTNENNNHKAQQQQIQELQQNLQTQINLNQDQLVSIQKLKEDLN 967
Query: 1594 QLTLSVDFSAGVFKEESTKVSNACDLLQ----EIENFLREIR---VETKVTIQEARHNVE 1436
QL + + + +S ++ DLLQ +N L++++ VE + I E +
Sbjct: 968 QLNQQITYKSEQLDSQSMDINQQKDLLQLQIISQQNQLKQLQQQIVENETVITEQSKKLN 1027
Query: 1435 EFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSM-EDKASSQSSTGDNDPKAXXXXXXX 1259
E S ++ L++ +Q+E ++ L + S+ + K Q
Sbjct: 1028 ETSQDLEKLKFDLNQVE----IEKGKLFQQQEDSLIQIKDLLQKIEQGEQHNLKLKDQIE 1083
Query: 1258 XXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNA----------EMGKFLCLCNS 1109
+ N+ + K +++ E M + L C+ A + K + N+
Sbjct: 1084 QQEQRLQDNIAELQIKQEEINEMAMKEQASKFELDCLKAKCLSYELQIEDQEKLISQQNN 1143
Query: 1108 MVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDV----ENVQKELLI 941
+I + +DL N+ +L+ ++ + + + A D+ +N+++E+
Sbjct: 1144 QAQQLSEIQEQLQDLQKNNEELQQNLNDKE----QNYDILQNAYYDIGDQKKNLEEEIED 1199
Query: 940 WKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQ 761
I K ++ ++ I L E+I Q + + + +Q + +
Sbjct: 1200 KNQEISIQNRDLKIYKEQIDQNKALINQLQEQIAQFRNSANINFAENCKLNEQVQMMKKE 1259
Query: 760 LTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLN-----QNVNYPLEATVNI 596
L Q + + D I ++E +LQ+ Q + + +N L+ T
Sbjct: 1260 LESYQIDSKQNLDERSDKIKDLEQQIIDLQNELENQQFQIQYKDSKIEELNNNLQET--- 1316
Query: 595 GFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQ 416
+++D+ E+ + + K+ + E + E +I+ Q ++E Q ++ +QQ
Sbjct: 1317 --SENLDDIKQELEITSRQLKNEQAQKEEELKCKQQLEGIIQ-QQKLEAQQYILTTNQQQ 1373
Query: 415 NTKLEL 398
L L
Sbjct: 1374 ENLLSL 1379
Score = 76.6 bits (187), Expect = 4e-11
Identities = 119/585 (20%), Positives = 248/585 (42%), Gaps = 54/585 (9%)
Frame = -2
Query: 2215 KEKNISEDLKETVKNLQSDLDIEQKLS-TDRQ--SEIYSLSAELERITQSEQMSLKRLKE 2045
K + ++ +L+ET +NL DI+Q+L T RQ +E EL+ Q E + ++ E
Sbjct: 1305 KIEELNNNLQETSENLD---DIKQELEITSRQLKNEQAQKEEELKCKQQLEGIIQQQKLE 1361
Query: 2044 AEQTLLEAESERESLKA-------------ELEESISVLKQELSSARLQIESLEKELNQA 1904
A+Q +L ++E+L + L+ IS L+ E + ++E L + LNQA
Sbjct: 1362 AQQYILTTNQQQENLLSLHNKIIEYCNEIESLKNQISTLQIECEKQQKEMEVLNENLNQA 1421
Query: 1903 N----EEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVI 1736
N ++ L +Q+ + S+++ ++ E Q +++NEI +
Sbjct: 1422 NTLLEDQKSNLENSEFQINYFQTQSKEIKIQYDQLQEKL-----QDLEQENEILNRNQSN 1476
Query: 1735 EQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVF 1556
++ E+ Q E + E ++ L++ L+ + + ++ + +L +++
Sbjct: 1477 NAQKQEQIQNEKYILQQE------ISQLKQSLATLFEERQNNQDRIQELIFTIELQ---- 1526
Query: 1555 KEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSN 1376
K E K +L+ E L++ +E + + N+E + +K + + L+ N
Sbjct: 1527 KSEDAKKDQKIELITNQELDLQQRLIELQEQNTTYQQNIESIQNQLKDEQLITENLKQQN 1586
Query: 1375 TMDH---DTLSSTHQGSMEDK-ASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKS 1208
D D L + + + + + + RQ + +E K
Sbjct: 1587 EKDQKQIDELKNIEIVQLNQQIVNLKEKIAFLEQNEIQTSELSSHLENLRQEKQIKEQKE 1646
Query: 1207 KQM-EEYKMLQAELNNWLSCMN-------AEMGKFLCLCNSM--VYLEGDILKYKEDLLL 1058
K EE L+ E+NN+ + +N + L M + ++ + LK +E L+
Sbjct: 1647 KLFREENDKLKEEINNFKNQINQLERDNITNEQNYHQLQEEMKTIEIKYEQLKTQEQQLI 1706
Query: 1057 NHGQLRAE-MSSLKI-------ELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSK 902
Q ++E +S+LK+ +L + N + + + + ++ + + E Q +
Sbjct: 1707 QLNQDKSEQISNLKVIQTDFEQKLEQLNNEIKVYQEEKQTQENKISQLNELQLQLENQRE 1766
Query: 901 AFQLELKHANMSI-----------CSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLT 755
+ LEL+ N I C +EKI Q+ + +T L K+ + ++ +L+
Sbjct: 1767 SITLELEQLNEQIKDLKKQSEINACQQNEKIDQLTNQ----ITLLQQKNEEQENQIKELS 1822
Query: 754 LAQEEISSTK-EMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVN 623
L EE+ + + ++ +A +T L ++ Q+QE L N+ N
Sbjct: 1823 LQNEELQDQQLQFMEQLQTEKQAHNTQLSENY-QLQEKLQNELEN 1866
>ref|XP_001581403.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121915630|gb|EAY20417.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 4263
Score = 110 bits (275), Expect = 3e-21
Identities = 134/679 (19%), Positives = 300/679 (44%), Gaps = 58/679 (8%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
+I++ K ET+K LQS+++ ++ D+ +EI L + ++ + +++
Sbjct: 1481 EIEQHKQTISQRDETIKQLQSEIEQHKQTIADKNNEIEQLKNTISEREETIKQLQNEIEQ 1540
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQ 1865
+QT+ E ++E + K E+E+ KQ +S+ +IE L+K +++ + E++ L K
Sbjct: 1541 HKQTMAERDAEIQKNKEEIEQQ----KQTISNNNNEIEQLKKTISERDAEIEQLKK---T 1593
Query: 1864 VLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKE--VEERQREC--- 1700
+ E +E +QL ++ + + S ++ K + + I +KE +++ Q E
Sbjct: 1594 IAERDESIKQLQNEIEQHKQTISQRDAEIEQLKQTVQQRDQTIAEKEDLIKQLQSEIEQH 1653
Query: 1699 MLAASERSNDI-----NVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKV 1535
S+++N+I VNA ++ + + +I + + +++ + + +++ +
Sbjct: 1654 KQTISDKNNEIEQLKQTVNARDEAIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQTI 1713
Query: 1534 SNACDLLQEIENFLREIR---VETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDH 1364
S + +++++N + + + + I++ + V++ + E L QL++
Sbjct: 1714 SQRDETIKQLQNEIEQHKQTISQRDAEIEQLKQTVQQSDQTIAEKEDLIKQLQSEIEQHK 1773
Query: 1363 DTLSSTH---QGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEE 1193
T++ Q + E+ + + D E QN + + K++E+
Sbjct: 1774 QTIAERDAEIQKNKEEIEQQKQTISQRDES------IKQMQSEIEQNKQTIADREKEIEQ 1827
Query: 1192 YKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRA-----EMS 1028
+K AE +N + + E+ + ++ + +I K KE++ + + A E
Sbjct: 1828 HKQTIAERDNSIKQLQEEIEQHK---QTIAERDAEIQKNKEEIQQKNEAINALTNEGEEK 1884
Query: 1027 SLKIELVEKNGFMGYAVLDVENVQKELL-IWKDRAMIAEGQS---KAFQLELKHANMSIC 860
LKI +E N ++ N KEL D + E Q+ K E+K N I
Sbjct: 1885 RLKILELEANN------ENLINKVKELNDSVSDLNLSTENQNSVVKQMTDEIKDLNKQIH 1938
Query: 859 SLSEKIQ----QIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNME 692
L K + QIEE++K + + +TK + L +L E +++TK ++ I N++
Sbjct: 1939 ELEVKSENQQKQIEEKDKEIQSLTNTK-AQNEELIKKLQEEVENLTNTKNQNEETIKNLQ 1997
Query: 691 ASDTNLQSHFNQIQEMLLNQ--------NVNYPLEATVNIGFDQ---------SMDEAVS 563
+L NQ ++++ Q N E T+ +Q + +E +
Sbjct: 1998 EQVQSLTETKNQNEDLIKKQQEQIQSLTNTKNENEETIKNLQEQVQSLTETKATNEETIK 2057
Query: 562 EIAVQTFPNKDTEDINTE-----------IAHTSDKDEEVI-KLQSQVENLQSLVQMLKQ 419
++ + +T+ N E +++T +++EE+I KLQ +++NL + ++
Sbjct: 2058 KLQGEVQSLTETKATNEEQIKKQQEEIQSLSNTKNENEELIKKLQEEIQNLTNTKTQNEE 2117
Query: 418 QNTKLELLAKKTSEMDPEK 362
Q KL+ + + + EK
Sbjct: 2118 QIKKLQEEIQNLQKQNAEK 2136
Score = 95.5 bits (236), Expect = 9e-17
Identities = 140/684 (20%), Positives = 289/684 (42%), Gaps = 51/684 (7%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELER-------- 2087
++ ++ +Q+ + ++ +K LQS+++ ++ +R +EI E+E+
Sbjct: 1741 IEQLKQTVQQSDQTIAEKEDLIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQTISQR 1800
Query: 2086 ----------ITQSEQMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQ 1937
I Q++Q R KE EQ + +ER++ +L+E I KQ ++ +
Sbjct: 1801 DESIKQMQSEIEQNKQTIADREKEIEQH-KQTIAERDNSIKQLQEEIEQHKQTIAERDAE 1859
Query: 1936 IESLEKELNQANEEVKVLS----KFRYQVLELEEYSQQL----------SADLSKVHEDY 1799
I+ ++E+ Q NE + L+ + R ++LELE ++ L +DL+ E+
Sbjct: 1860 IQKNKEEIQQKNEAINALTNEGEEKRLKILELEANNENLINKVKELNDSVSDLNLSTENQ 1919
Query: 1798 SAALRQLFDKKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKI 1619
++ ++Q+ D EI L + I + EV+ ++ + D + +L + E I
Sbjct: 1920 NSVVKQMTD---EIKDLNKQIHELEVKSENQQKQI----EEKDKEIQSLTNTKAQNEELI 1972
Query: 1618 RRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNV 1439
++L+ +V LT + + + K +V + L E +N ++ + + IQ +
Sbjct: 1973 KKLQEEVENLTNTKNQNEETIKNLQEQVQS----LTETKNQNEDLIKKQQEQIQSLTNTK 2028
Query: 1438 EEFSSVVKHL-EYLKSQLETSNTMDH--DTLSSTHQGSMEDKASSQSSTGDNDPKAXXXX 1268
E +K+L E ++S ET T + L Q E KA+++ +
Sbjct: 2029 NENEETIKNLQEQVQSLTETKATNEETIKKLQGEVQSLTETKATNEEQIKKQQEEIQSLS 2088
Query: 1267 XXXXXXXECRQNLENE-----ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMV 1103
E + L+ E K++ E+ K LQ E+ N L NAE + N+ +
Sbjct: 2089 NTKNENEELIKKLQEEIQNLTNTKTQNEEQIKKLQEEIQN-LQKQNAEKDDKINEFNAKL 2147
Query: 1102 YLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGF---MGYAVLDVENVQKELLIWKD 932
+ ++L + E++ L + EK+ + + D+EN + +L
Sbjct: 2148 ---STLSSSSDELTTKFINAQNEINQLTKQNNEKDNLISQLNQKISDLENAKSQL----- 2199
Query: 931 RAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTL 752
E + E + L E+ + +EE ++ +L T+ T+++ A+L
Sbjct: 2200 -----ENEKSQLIQEKTNLEQEKAQLLEQKKNLEEEKQ----KLETEKTNLEQEKAKLIE 2250
Query: 751 AQEEISSTKEMLKDFIDNMEASDTNL---QSHFNQIQEMLLNQNVNYPLEATVNIGFDQS 581
+ + K L + N+E L +++ Q + L+ + N E I +
Sbjct: 2251 EKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTN 2310
Query: 580 MDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLE 401
+++ ++ ++ N + E I ++ ++E KL + NL+ L ++ T LE
Sbjct: 2311 LEQEKAK-PIEEKTNLEQEKAKL-IEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLE 2368
Query: 400 -----LLAKKTSEMDPEKYFHFEE 344
L+ +KT+ ++ EK EE
Sbjct: 2369 QEKAKLIEEKTN-LEQEKAKLIEE 2391
Score = 94.0 bits (232), Expect = 3e-16
Identities = 141/753 (18%), Positives = 320/753 (42%), Gaps = 57/753 (7%)
Frame = -2
Query: 2221 IQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEA 2042
I ++ N + LK+ V + ++ ++ ++ + I L ++E+ Q + + +++
Sbjct: 1426 INEQSNTIDSLKQDVATKEEEIKQLKQTVSENEEVIKQLQTDIEQKDAEIQKNKEEIEQH 1485
Query: 2041 EQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQV 1862
+QT+ + + + L++E+E+ KQ ++ +IE L+ +++ E +K L
Sbjct: 1486 KQTISQRDETIKQLQSEIEQH----KQTIADKNNEIEQLKNTISEREETIKQLQN----- 1536
Query: 1861 LELEEYSQQLS---ADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECMLA 1691
E+E++ Q ++ A++ K E+ + + + NEI L++ I +++ E Q + +A
Sbjct: 1537 -EIEQHKQTMAERDAEIQKNKEEIEQQKQTISNNNNEIEQLKKTISERDAEIEQLKKTIA 1595
Query: 1690 ASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQ 1511
D ++ L+ ++ ++ I + + ++ QL +V ++ ++ DL++
Sbjct: 1596 ----ERDESIKQLQNEIEQHKQTISQRDAEIEQLKQTV-------QQRDQTIAEKEDLIK 1644
Query: 1510 EIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSM 1331
++++ + + K TI + + +E+ V + QL++ T++
Sbjct: 1645 QLQSEIE----QHKQTISDKNNEIEQLKQTVNARDEAIKQLQSEIEQHKQTIAERDAEIQ 1700
Query: 1330 EDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAEL---NNW 1160
++K + + ++ S++ E K LQ E+
Sbjct: 1701 KNKEEIE---------------------------QQKQTISQRDETIKQLQNEIEQHKQT 1733
Query: 1159 LSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYA 980
+S +AE+ + V + KEDL+ QL++E+ K + E++ +
Sbjct: 1734 ISQRDAEIEQL----KQTVQQSDQTIAEKEDLI---KQLQSEIEQHKQTIAERDAEIQKN 1786
Query: 979 VLDVENVQKELLIWKDRAMIAEGQSKAFQ---------LELKHANMSICSLSEKIQQIEE 827
++E QK+ + +D + I + QS+ Q E++ +I I+Q++E
Sbjct: 1787 KEEIEQ-QKQTISQRDES-IKQMQSEIEQNKQTIADREKEIEQHKQTIAERDNSIKQLQE 1844
Query: 826 REKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTK---EMLKDFIDNMEASDTNLQSHFNQ 656
+ ++ +D ++Q ++ E I++ E + I +EA++ NL + +
Sbjct: 1845 EIEQHKQTIAERDAEIQKNKEEIQQKNEAINALTNEGEEKRLKILELEANNENLINKVKE 1904
Query: 655 IQEMLLNQNVNYPLEATVNIGFD---QSMDEAVSEIAVQT-FPNKDTEDINTEI---AHT 497
+ + + + N++ + +V + +++ + E+ V++ K E+ + EI +T
Sbjct: 1905 LNDSVSDLNLSTENQNSVVKQMTDEIKDLNKQIHELEVKSENQQKQIEEKDKEIQSLTNT 1964
Query: 496 SDKDEEVI-KLQSQVE--------------NLQSLVQMLKQQNTKLELLAKKTSEM---- 374
++EE+I KLQ +VE NLQ VQ L + + E L KK E
Sbjct: 1965 KAQNEELIKKLQEEVENLTNTKNQNEETIKNLQEQVQSLTETKNQNEDLIKKQQEQIQSL 2024
Query: 373 ------DPEKYFHFEELCQSLVXXXXXXXXXXXXXXXKNQVLV-------KQVKEMQVTL 233
+ E + +E QSL + Q L +Q+K+ Q +
Sbjct: 2025 TNTKNENEETIKNLQEQVQSLTETKATNEETIKKLQGEVQSLTETKATNEEQIKKQQEEI 2084
Query: 232 QSESPMEGETDSISENAIGSQPAGKLSTELHNV 134
QS S + E + + + KL E+ N+
Sbjct: 2085 QSLSNTKNENEELIK---------KLQEEIQNL 2108
Score = 93.6 bits (231), Expect = 3e-16
Identities = 150/709 (21%), Positives = 302/709 (42%), Gaps = 99/709 (13%)
Frame = -2
Query: 2233 VRLDIQKEKNISEDLK--ETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSL 2060
V +D QK+ + +K + KNL+ D QK++ + Q+ IY L + + Q+ +M
Sbjct: 3445 VIIDRQKKFVGQQKMKIADLEKNLKESNDEAQKMTKNLQTTIYELEDRCQNLNQTIEMKN 3504
Query: 2059 KRLKEAEQTLLEAESERESLKAE--------------------------LEESISVLKQE 1958
RL+E E+T+ + E E LK + L++++S ++
Sbjct: 3505 FRLRENEKTIEDLNKEIEFLKGKIDILSREISMYSDNSSKDNLISKIVSLQKTVSEKDEQ 3564
Query: 1957 LSSAR------LQIE-SLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDY 1799
L+ A+ L+IE +++E++Q N + L + +VL L + S + + + SKV D
Sbjct: 3565 LNDAKINSNNSLEIEDKMQQEIDQKNSRIHHLEN-QMRVL-LNKASHENAKEESKVKIDL 3622
Query: 1798 SAALRQLFDKKNEITCLQE---VIEQK------EVEERQRECMLAASERSNDIN-VNALE 1649
A +L + +N+ + LQE ++ K ++E+Q E + A + +NDIN ++ L+
Sbjct: 3623 KKANVKLSNLENDFSSLQEENAALKSKVSKLELVIKEKQSEINIMAQKNNNDINEISELK 3682
Query: 1648 KKL--------------SAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQ 1511
KL +I +L ND+ +D S + +K++ L Q
Sbjct: 3683 SKLRKQNEDFTQEKSSAEKQRSEIDQLTNDLKAKNNELDDSKSEIRILKSKIN---QLQQ 3739
Query: 1510 EIENFLREIRVET-KVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGS 1334
+ + ++ E+ K++ E + +E + K L+ K+ E + ++ L + Q
Sbjct: 3740 DFDAKNHSLQKESEKLSQLEEKMKEKELELLNKSLDNDKAAKEIIEKLQNENLEQSKQLK 3799
Query: 1333 MEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQ---AELNN 1163
++K Q ND QN +NE+ E++K+ + EL +
Sbjct: 3800 KKEKDIEQMKQILND--LNNEQGELKGKIMTLQN-DNEQITKTSQEKFKLNEKKSEELVS 3856
Query: 1162 WLSCMNAEMG-KFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAE-MSSLKIELVEKNGFM 989
++ +N E+ K + +++ E +I K K D L Q+ E +++L+ E+++
Sbjct: 3857 MINKLNDEIAEKNKTINGTLLQKEKEITKLKND--LEQSQITNERITNLESEMMKMKQLN 3914
Query: 988 GYAVLDVENVQKELLIWKDRAMIAEGQSKAFQ----LELKHANMSICSLSEKIQQIEERE 821
+ D+ +EL+ + + E + K Q L+ S L KI ++E+
Sbjct: 3915 DDLMNDINRYNEELI--EKENELQELREKLIQSGNNLQKVTPEQSYFDLQMKITELEDII 3972
Query: 820 KVLLTQLSTKDTDMQHLAAQLTLAQEEISSTK-------------------EMLKDFIDN 698
K +QL K ++ +L ++L +S K KD ID
Sbjct: 3973 KDKNSQLENKTNEITNLYSKLYNTSPPSNSKKPRNTKLEVEKMRIKMAELENKNKDLIDQ 4032
Query: 697 MEASDTNLQSHFNQ----IQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKD 530
+++LQ+ NQ + M N+N +N+ + + + + + +
Sbjct: 4033 NTRMNSDLQAQINQNNKLKRHMKDNENNFNSQINQLNLKLQKVVSDYEARLLILDNSKNQ 4092
Query: 529 TEDINTEIAHTSDKDEEVIKLQSQV-------ENLQSLVQMLKQQNTKL 404
T+ +N K+EE++ + Q+ + L++ +++ K+QN L
Sbjct: 4093 TQRVNELRERIKQKNEEILSKEKQINENKLENDKLKNEIELSKKQNEDL 4141
Score = 90.5 bits (223), Expect = 3e-15
Identities = 131/656 (19%), Positives = 271/656 (41%), Gaps = 25/656 (3%)
Frame = -2
Query: 2221 IQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSE---QMSLKRL 2051
IQ N + +ET+KNLQ + + + I L E++ +T+++ + +K+
Sbjct: 2021 IQSLTNTKNENEETIKNLQEQVQSLTETKATNEETIKKLQGEVQSLTETKATNEEQIKKQ 2080
Query: 2050 KEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELN----QANEEVKVL 1883
+E Q+L ++E E L +L+E I L + QI+ L++E+ Q E+ +
Sbjct: 2081 QEEIQSLSNTKNENEELIKKLQEEIQNLTNTKTQNEEQIKKLQEEIQNLQKQNAEKDDKI 2140
Query: 1882 SKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQ----KEVEE 1715
++F ++ L S +L+ + + +Q +K N I+ L + I K E
Sbjct: 2141 NEFNAKLSTLSSSSDELTTKFINAQNEINQLTKQNNEKDNLISQLNQKISDLENAKSQLE 2200
Query: 1714 RQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKV 1535
++ ++ LE+K + E K ++LE + + L A + +E++
Sbjct: 2201 NEKSQLIQEKTNLEQEKAQLLEQKKNLEEEK-QKLETEKTNLEQE---KAKLIEEKTNLE 2256
Query: 1534 SNACDLLQEIENFLREIR--VETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHD 1361
L++E N +E +E K +++ + + E + +LE K++L T
Sbjct: 2257 QEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKT---NLEQEKAKLIEEKT---- 2309
Query: 1360 TLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECK------SKQM 1199
L +E+K + + + E + NLE E+ K + +
Sbjct: 2310 NLEQEKAKPIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQ 2369
Query: 1198 EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSL- 1022
E+ K+++ + N + E K + ++ + +++ K +L +L E ++L
Sbjct: 2370 EKAKLIEEKTN-----LEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLE 2424
Query: 1021 --KIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSE 848
K +L+E+ ++E + +LL Q K + E + L E
Sbjct: 2425 QEKAKLIEEK-------TNLEQEKSQLL----------DQKKNLEEEKQRLETEKAKLIE 2467
Query: 847 KIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFID--NMEASDTNL 674
+E+ + LL Q + + L + AQ+ I + ++D N++ D +L
Sbjct: 2468 DKTNLEQEKAQLLEQKKNLEEEKAKLEEEKAQAQKTIEEKDQEIEDLTSQINVKTKDLSL 2527
Query: 673 -QSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHT 497
+S FN N + ++T+ +++ + + EI K E+
Sbjct: 2528 LESDFN-------NMSFTNADQSTMISNYEKELSDKNKEINDLQNQLKQMTQNRDELQSK 2580
Query: 496 SDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEKYFHFEELCQSL 329
SDK E I+ + +N+Q+L L+Q+N + E L ++ ++ E ++ Q L
Sbjct: 2581 SDKLNEEIE---EKKNIQNLESSLEQKNKENEDLKQQLNKTQGELSAQLQQKTQEL 2633
Score = 88.2 bits (217), Expect = 1e-14
Identities = 118/629 (18%), Positives = 267/629 (42%), Gaps = 10/629 (1%)
Frame = -2
Query: 2218 QKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAE 2039
Q+++ I+E ++ +K LQS+++ ++ +D+ +EI L + ++ + +++ +
Sbjct: 1631 QRDQTIAEK-EDLIKQLQSEIEQHKQTISDKNNEIEQLKQTVNARDEAIKQLQSEIEQHK 1689
Query: 2038 QTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRY 1868
QT+ E ++E + K E+E ++IS + + + +IE ++ ++Q + E++ L +
Sbjct: 1690 QTIAERDAEIQKNKEEIEQQKQTISQRDETIKQLQNEIEQHKQTISQRDAEIEQLKQTVQ 1749
Query: 1867 Q----VLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQREC 1700
Q + E E+ +QL +++ + + + ++ K EI ++ I Q++ +Q +
Sbjct: 1750 QSDQTIAEKEDLIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQTISQRDESIKQMQS 1809
Query: 1699 MLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACD 1520
+ N + EK++ ++ I +N + QL ++ E ++ +
Sbjct: 1810 EI----EQNKQTIADREKEIEQHKQTIAERDNSIKQLQEEIEQHKQTIAERDAEIQKNKE 1865
Query: 1519 LLQ---EIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSS 1349
+Q E N L E ++ I E N E + VK L S L S + +S
Sbjct: 1866 EIQQKNEAINALTNEGEEKRLKILELEANNENLINKVKELNDSVSDLNLST----ENQNS 1921
Query: 1348 THQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAEL 1169
+ ++ + + K+ + Q+L N + +++++ K LQ E+
Sbjct: 1922 VVKQMTDEIKDLNKQIHELEVKSENQQKQIEEKDKEIQSLTNTKAQNEEL--IKKLQEEV 1979
Query: 1168 NNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFM 989
N + N L + L + EDL+ + +++ K E E
Sbjct: 1980 ENLTNTKNQNEETIKNLQEQVQSLT-ETKNQNEDLIKKQQEQIQSLTNTKNENEE----- 2033
Query: 988 GYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLL 809
++N+Q+++ + E K Q E++ + + E+I++ +E +
Sbjct: 2034 -----TIKNLQEQVQSLTETKATNEETIKKLQGEVQSLTETKATNEEQIKKQQEE----I 2084
Query: 808 TQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQN 629
LS + + L +L + +++TK ++ I ++ NLQ + + + N
Sbjct: 2085 QSLSNTKNENEELIKKLQEEIQNLTNTKTQNEEQIKKLQEEIQNLQKQNAEKDDKINEFN 2144
Query: 628 VNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVEN 449
S DE ++ F N E IN ++KD + +L ++ +
Sbjct: 2145 AKLST-------LSSSSDELTTK-----FINAQNE-INQLTKQNNEKDNLISQLNQKISD 2191
Query: 448 LQSLVQMLKQQNTKLELLAKKTSEMDPEK 362
L++ L +N K +L+ +KT+ ++ EK
Sbjct: 2192 LENAKSQL--ENEKSQLIQEKTN-LEQEK 2217
Score = 83.2 bits (204), Expect = 4e-13
Identities = 131/742 (17%), Positives = 299/742 (40%), Gaps = 28/742 (3%)
Frame = -2
Query: 2233 VRLDIQKEKNI----SEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQM 2066
+ + I+ + NI +DLK+T + L+ R+ +I AE I + +
Sbjct: 1295 MEMTIKNQANIIKAKDDDLKQTKEILEY-----------REEQIEKFIAESVSIRDAIET 1343
Query: 2065 SLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKV 1886
+R+ E E L + + E AE++E R +E L K+L +A E++ V
Sbjct: 1344 LKQRISELEMLLEKKDKENNDKIAEIQE----------ENRQTLEQLAKQLQEAEEDINV 1393
Query: 1885 L----SKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVE 1718
L + ++ E ++ +Q++ D+ + E + ++ N I L++ + KE E
Sbjct: 1394 LEGNCQVYEQEIAEKDKQIEQMTNDIKSLEE-------VINEQSNTIDSLKQDVATKEEE 1446
Query: 1717 ERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTK 1538
+Q L++ +S E I++L+ D+ Q + + ++
Sbjct: 1447 IKQ------------------LKQTVSENEEVIKQLQTDIEQKDAEIQKNKEEIEQHKQT 1488
Query: 1537 VSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDT 1358
+S + ++++++ + + K TI + + +E+ + + E QL+ T
Sbjct: 1489 ISQRDETIKQLQSEIE----QHKQTIADKNNEIEQLKNTISEREETIKQLQNEIEQHKQT 1544
Query: 1357 LSSTH---QGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECK---SKQME 1196
++ Q + E+ + + +N+ + ++ E E+ K +++ E
Sbjct: 1545 MAERDAEIQKNKEEIEQQKQTISNNNNE-----IEQLKKTISERDAEIEQLKKTIAERDE 1599
Query: 1195 EYKMLQAEL---NNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSS 1025
K LQ E+ +S +AE+ + V + KEDL+ QL++E+
Sbjct: 1600 SIKQLQNEIEQHKQTISQRDAEIEQL----KQTVQQRDQTIAEKEDLI---KQLQSEIEQ 1652
Query: 1024 LKIELVEKNGFMGYAVLDV-------ENVQKELLIWKDRAMIAEGQSKAFQLELKHANMS 866
K + +KN + V + +Q E+ K + + + + E++ +
Sbjct: 1653 HKQTISDKNNEIEQLKQTVNARDEAIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQT 1712
Query: 865 ICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEAS 686
I E I+Q++ + +S +D +++ L + + + I+ ++++K +E
Sbjct: 1713 ISQRDETIKQLQNEIEQHKQTISQRDAEIEQLKQTVQQSDQTIAEKEDLIKQLQSEIEQH 1772
Query: 685 DTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDT-EDINTE 509
+ +IQ+ N+ + T++ DE++ ++ + NK T D E
Sbjct: 1773 KQTIAERDAEIQK---NKEEIEQQKQTIS-----QRDESIKQMQSEIEQNKQTIADREKE 1824
Query: 508 IAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEKYFHFEELCQSL 329
I + + + + ++ LQ ++ KQ + + +K E +K E +L
Sbjct: 1825 I---EQHKQTIAERDNSIKQLQEEIEQHKQTIAERDAEIQKNKEEIQQK----NEAINAL 1877
Query: 328 VXXXXXXXXXXXXXXXKNQVLVKQVKEMQVTLQSESPMEGETDSISENAIGSQPAGK--- 158
N+ L+ +VKE+ ++S + + ++N++ Q +
Sbjct: 1878 TNEGEEKRLKILELEANNENLINKVKEL-----NDSVSDLNLSTENQNSVVKQMTDEIKD 1932
Query: 157 LSTELHNVHGNTERVPLQLLNK 92
L+ ++H + +E Q+ K
Sbjct: 1933 LNKQIHELEVKSENQQKQIEEK 1954
Score = 83.2 bits (204), Expect = 4e-13
Identities = 136/696 (19%), Positives = 298/696 (42%), Gaps = 57/696 (8%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVK-------NLQSDLDIEQKLSTDRQSEIYSLSAELERI 2084
+DA + ++QK+ +++L+ +K L++ L K D+ I SL +
Sbjct: 3266 VDATKRELQKQLQNNKELQNQIKMTKEQFAKLEAKLQSVVKKLNDKDQRIDSLMSSDPNN 3325
Query: 2083 TQSEQMSLK---------RLK-------EAEQTLLEAESERESLKAELEESISVLKQELS 1952
Q+ Q++ + +LK Q+L + ++S K++L+ES + LK EL
Sbjct: 3326 KQTNQLNKQISDLNLENEKLKTRVDIITRENQSLKDDLESQKSQKSKLDESCNALKTELI 3385
Query: 1951 SARLQIESLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFD 1772
+ + ++ +++L + E++ + +K Q+ EL+ A+ + ++ + ++ +
Sbjct: 3386 NKKSIMDQYKEKLKELMEQINLKNK---QISELK-------AEFNGSDDEDRKSYVKVIE 3435
Query: 1771 KKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQ 1592
++ EIT L+ +I++++ Q++ +A E++ + + +K + I LE+
Sbjct: 3436 QEGEITELKVIIDRQKKFVGQQKMKIADLEKNLKESNDEAQKMTKNLQTTIYELEDRCQN 3495
Query: 1591 LTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKH 1412
L +++ +E + DL +EIE +I + ++ I N + + + K
Sbjct: 3496 LNQTIEMKNFRLRENEKTIE---DLNKEIEFLKGKIDILSR-EISMYSDNSSKDNLISKI 3551
Query: 1411 LEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQN 1232
+ K+ E ++ ++S + +EDK + D + +
Sbjct: 3552 VSLQKTVSEKDEQLNDAKINSNNSLEIEDKMQQEI---DQKNSRIHHLENQMRVLLNKAS 3608
Query: 1231 LENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLL-- 1058
EN + +SK + K +L+N + ++ + L + + LE I + + ++ +
Sbjct: 3609 HENAKEESKVKIDLKKANVKLSNLENDFSSLQEENAALKSKVSKLELVIKEKQSEINIMA 3668
Query: 1057 --NHGQLRAEMSSLKIELVEKN--------------GFMGYAVLDVENVQKELLIWKDRA 926
N+ + E+S LK +L ++N + D++ EL K
Sbjct: 3669 QKNNNDIN-EISELKSKLRKQNEDFTQEKSSAEKQRSEIDQLTNDLKAKNNELDDSKSEI 3727
Query: 925 MIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLT--L 752
I + + Q + N S+ SEK+ Q+EE+ K +L K D A ++ L
Sbjct: 3728 RILKSKINQLQQDFDAKNHSLQKESEKLSQLEEKMKEKELELLNKSLDNDKAAKEIIEKL 3787
Query: 751 AQEEISSTKEMLKDF--IDNMEASDTNLQSHFNQIQEMLLN-QNVNYPLEATVNIGFDQS 581
E + +K++ K I+ M+ +L + +++ ++ QN N + T F +
Sbjct: 3788 QNENLEQSKQLKKKEKDIEQMKQILNDLNNEQGELKGKIMTLQNDNEQITKTSQEKFKLN 3847
Query: 580 MDEAVSEIAVQTFPNKDTEDINTEIAHTS-DKDEEVIKLQSQVE----------NLQSLV 434
++ +++ N + + N I T K++E+ KL++ +E NL+S +
Sbjct: 3848 EKKSEELVSMINKLNDEIAEKNKTINGTLLQKEKEITKLKNDLEQSQITNERITNLESEM 3907
Query: 433 QMLKQQNTKLELLAKKTSEMDPEKYFHFEELCQSLV 326
+KQ N L + +E EK +EL + L+
Sbjct: 3908 MKMKQLNDDLMNDINRYNEELIEKENELQELREKLI 3943
Score = 79.0 bits (193), Expect = 8e-12
Identities = 122/634 (19%), Positives = 268/634 (42%), Gaps = 15/634 (2%)
Frame = -2
Query: 2230 RLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAEL---ERITQSEQMSL 2060
+ ++++EK+ D K+ ++ + L+ E+ + ++ + A+L ++ + E+ L
Sbjct: 2434 KTNLEQEKSQLLDQKKNLEEEKQRLETEKAKLIEDKTNLEQEKAQLLEQKKNLEEEKAKL 2493
Query: 2059 KRLK-EAEQTLLEAESERESLKAELE---ESISVLKQELSSARL-------QIESLEKEL 1913
+ K +A++T+ E + E E L +++ + +S+L+ + ++ I + EKEL
Sbjct: 2494 EEEKAQAQKTIEEKDQEIEDLTSQINVKTKDLSLLESDFNNMSFTNADQSTMISNYEKEL 2553
Query: 1912 NQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIE 1733
+ N+E+ L Q+ ++ + +L + K++E+ ++K I L+ +E
Sbjct: 2554 SDKNKEINDLQN---QLKQMTQNRDELQSKSDKLNEE--------IEEKKNIQNLESSLE 2602
Query: 1732 QKEVEERQRECMLAASERSNDINVNALEKKLSA-YEGKIRRLENDVSQLTLSVDFSAGVF 1556
QK E + L N + +LSA + K + LEN L+ +F+
Sbjct: 2603 QKNKENEDLKQQL-----------NKTQGELSAQLQQKTQELEN------LTKEFNDLKQ 2645
Query: 1555 KEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSN 1376
K E T N +EI N + + K Q + V E + E + L+ +
Sbjct: 2646 KSEQTIAQNN----EEIANLKKNVAERDKKISQLLENEVNELKKKLSDKENENTSLKNTI 2701
Query: 1375 TMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQME 1196
+ + +++ + ++ DK + + +N + E + K ++++
Sbjct: 2702 SERENEINNLKK-NVSDKENEINQLKNN---------------LTMRETELNKMKDEEVK 2745
Query: 1195 EYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKI 1016
K + A+ + L +N GKF N++ ++ + KE + L ++ +K
Sbjct: 2746 NAKQIIAQKDKDLEELN---GKFNDTNNNLSKANDELKQLKEQI----ESLNKQIEQMKC 2798
Query: 1015 ELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQ 836
K + +++ ++ L D+ + Q E+K ++ E++++
Sbjct: 2799 SNNLKESEIKQLTSNLQKYKQALKELNDQNKQKDSQINQLNNEMKELQQTLKQTQEQLKE 2858
Query: 835 IEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQ 656
+++ K L+TK+ + A L E+ ++ + D +N++ D L
Sbjct: 2859 TQDQLKQTQETLATKEKEFAKSAEDL---NNELKKKQQAIDDLQNNLKQKDAEL------ 2909
Query: 655 IQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEV 476
+ LEA N F+ +A +EIA K+ E + ++A+TS K+ E
Sbjct: 2910 -------TDTKQKLEAKTN-EFNDLKQKAENEIASL---RKEIEQLKAKLANTS-KELEA 2957
Query: 475 IKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEM 374
K +S ++ K++N KL++ K +EM
Sbjct: 2958 SKSESDLQ---------KKENDKLKVNLAKIAEM 2982
Score = 71.6 bits (174), Expect = 1e-09
Identities = 137/743 (18%), Positives = 300/743 (40%), Gaps = 111/743 (14%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
++ K + + LKE +++L ++ + + ++SEI L++ L++ Q+ + + K+
Sbjct: 2771 NLSKANDELKQLKEQIESLNKQIEQMKCSNNLKESEIKQLTSNLQKYKQALKELNDQNKQ 2830
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQ---ELSSARLQIESLEKELNQANEEV-KVLSK 1877
+ + + +E + L+ L+++ LK+ +L + + + EKE ++ E++ L K
Sbjct: 2831 KDSQINQLNNEMKELQQTLKQTQEQLKETQDQLKQTQETLATKEKEFAKSAEDLNNELKK 2890
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKK----NEITCLQEVIEQKEVEERQ 1709
+ + +L+ +Q A+L+ + A + D K NEI L++ IEQ + +
Sbjct: 2891 KQQAIDDLQNNLKQKDAELTDTKQKLEAKTNEFNDLKQKAENEIASLRKEIEQLKAKLAN 2950
Query: 1708 RECMLAASERSNDINVNALEK----------------------------KLSAYEGKIRR 1613
L AS+ +D+ +K K+ + KI+
Sbjct: 2951 TSKELEASKSESDLQKKENDKLKVNLAKIAEMYKTLKSESENNSAKSNDKIKQMQEKIQN 3010
Query: 1612 LENDVSQLTLSVD--FSAGVFKEESTKVSNACDL---------LQEIENFLREIRVE--- 1475
LE V ++ L+ + + ++E+ ++ N L ++E E RE ++
Sbjct: 3011 LEIQVEKMKLANENLTNENKLQKETIEMLNKKLLESNKSLTASIKEYETLKRENNLQKDQ 3070
Query: 1474 -TKVTIQEARHNVEEFSSVVKHLEYLKSQLE------TSNTMDHDTLSSTHQGSMEDKAS 1316
TK+T Q + ++F+ + K + S+L + + L S +Q E
Sbjct: 3071 ITKLTSQ-VQKLTQDFTQLKKEKAEVDSKLNELLDLLAQKDKEIERLKSENQKLNE---L 3126
Query: 1315 SQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEM 1136
Q T D + K C L E K+K++E ++ LNN L+ E+
Sbjct: 3127 YQQITKDLEEK---EFLIQSQNNRCIDLLNLTEKKNKEIETLQISNDSLNNSLTKSQMEL 3183
Query: 1135 GKFLCL----------CNSMVYLEGDILKYKEDLLL---NHGQLRAEMSSLKIELVEKNG 995
+ L N + L + +L L G ++ +L ++ KN
Sbjct: 3184 REKSTLLENAKDKITESNRKLALFDRLSANSSELNLTSSGRGIKKSSSMNLSTDMDSKNK 3243
Query: 994 FMGYAVLDVENVQKELLIWKDRAMIAEGQ-------SKAFQLELKHANMSICSLSEKIQQ 836
+ + +++ L + K+ + + +K Q ++K L K+Q
Sbjct: 3244 IINQQEQTIIGLEQSLKVSKNEVDATKRELQKQLQNNKELQNQIKMTKEQFAKLEAKLQS 3303
Query: 835 I-------EEREKVLLT---------QLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFI 704
+ ++R L++ QL+ + +D+ +L + I+ + LKD +
Sbjct: 3304 VVKKLNDKDQRIDSLMSSDPNNKQTNQLNKQISDLNLENEKLKTRVDIITRENQSLKDDL 3363
Query: 703 DNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTE 524
++ ++ + L N ++ L+N+ ++ + + + E + +I ++ NK
Sbjct: 3364 ESQKSQKSKLDESCNALKTELINKK-------SIMDQYKEKLKELMEQINLK---NKQIS 3413
Query: 523 DINTEIAHTSDKDE----EVIKLQSQVENLQSLVQMLK----QQNTKLELLAKKTSEMDP 368
++ E + D+D +VI+ + ++ L+ ++ K QQ K+ L K E +
Sbjct: 3414 ELKAEFNGSDDEDRKSYVKVIEQEGEITELKVIIDRQKKFVGQQKMKIADLEKNLKESND 3473
Query: 367 E----------KYFHFEELCQSL 329
E + E+ CQ+L
Sbjct: 3474 EAQKMTKNLQTTIYELEDRCQNL 3496
>ref|XP_001323236.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121906097|gb|EAY11013.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 2458
Score = 110 bits (275), Expect = 3e-21
Identities = 149/725 (20%), Positives = 309/725 (42%), Gaps = 93/725 (12%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSE---IYSLSAELERITQSEQMSLKR 2054
+I K K+ E+LK+ +++ + + + E D +E I +L +E+E + + S+K
Sbjct: 1005 EIHKLKSEIEELKKKLESSEQNKEEENNGWGDENTETENIDNLKSEIEELNKKLDESIKS 1064
Query: 2053 LKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKEL---NQANEEVKVL 1883
E ++ + E + E E L+ +L E+ S ++E++ + Q+E L ++L NQ NEE++
Sbjct: 1065 NDEKQKKIEEMKQENEELQTQLFENNS--EEEINKFKSQVEELTQKLQESNQKNEELQ-- 1120
Query: 1882 SKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRE 1703
S+ Q E+++ +Q + K+ ++ S D KNEI+ LQ+ E+ + +++
Sbjct: 1121 SQTEKQNNEIDDLKKQKEEENEKLQKEIS-------DLKNEISQLQQKEEENGSDLQKQI 1173
Query: 1702 CMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNAC 1523
+L + ND ++ L K++ + + + +++ L + + K E+ K N
Sbjct: 1174 EVLKQTNEKNDEDIEQLAKQIDELQTEKEKQNEEINDLKSQLQ-NVSEIKSENEKQKNEI 1232
Query: 1522 DLL---------------------QEIENFLREIRVETKVTIQEARHNVEE--------- 1433
D L +EI EI E K ++E+ N EE
Sbjct: 1233 DDLKKENEELQTQLFEIGNNQEKEEEIHKLKSEIE-ELKKKLEESEQNKEEENIDNLKSE 1291
Query: 1432 ---FSSVVKHLEYLKSQLETSNT-MDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXX 1265
+K LE QL+ N+ + + S Q S E++ + +++
Sbjct: 1292 NETLKEEIKRLESDNEQLKKQNSELQQENKSLHQQQSKEEEENGWGEENESEELKSENES 1351
Query: 1264 XXXXXXECRQNLENEECKSK---------QMEEYKMLQAELNNWLSCMNAEMGKFLCLCN 1112
E ++ L+ +E + + + E+YK + L N +N K L N
Sbjct: 1352 LKKQIEELKEQLKQKEDQGQEENGWGDENETEDYKSQISALENEKRTLNK---KIKDLAN 1408
Query: 1111 SMVYLEGDILKYKEDL--LLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIW 938
+ L+ K ++ L + ++ + +E E + + E +++
Sbjct: 1409 GLKTLKSKNEKLEQQLKDINSNNSTNDNSKDISVEFNETEEKITELEFENEELRRNNESL 1468
Query: 937 KDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQL 758
+ + Q+ E K + + +L E+++++EE +L ++++HL ++L
Sbjct: 1469 SEEKKTLQKQNNKLVSENKTLSDEVSTLREQVEELEEETISTSNELR---SEIEHLRSEL 1525
Query: 757 TLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEML---------LNQNVNYPLEAT 605
L ++E+ TK + ++N E +++N+ S + +E + L Q P +
Sbjct: 1526 VLREQELEQTKNN-NNNVNNNENNNSNVHSDQSIYEEKISLLKQQLEELKQQQQKPFDHE 1584
Query: 604 VNIGFD---------QSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVE 452
N D + + + E+ Q F +T + N + +K++E+ KL+S++E
Sbjct: 1585 DNNDSDEINKLKKEIEDLKQENEELQNQLFEGGETNENNNQ-----EKEDEIHKLKSEIE 1639
Query: 451 NLQSLVQMLKQ-----------QNT----------KLELLAKKTSEM---DPEKYFHFEE 344
L+ ++ +Q +NT ++E L KK +E+ + EK EE
Sbjct: 1640 ELKKKLESSEQNKEEENNGWGDENTETENIENLKSEIEELNKKLNELSKSNDEKQKKIEE 1699
Query: 343 LCQSL 329
L Q L
Sbjct: 1700 LEQKL 1704
Score = 86.7 bits (213), Expect = 4e-14
Identities = 134/618 (21%), Positives = 264/618 (42%), Gaps = 24/618 (3%)
Frame = -2
Query: 2197 EDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTLLEAE 2018
++L + +L++ L + LS EI SL A++ + Q+ K +E EQ L+AE
Sbjct: 213 QELNAQITDLKNQLAAKDSLS----DEIASLKAQIAELNQNNS---KSSEENEQ--LKAE 263
Query: 2017 SERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKF--RYQVLELEEY 1844
S++++ + +S LK+ + + QI ++E+N L F Q +E+E+Y
Sbjct: 264 SQKDASSDDKNSDLSRLKKAVVQLKKQIAQKDQEINDLKTSNMQLQNFNNETQNVEIEKY 323
Query: 1843 SQQLSADLSKVHEDYSAALRQL-FDKKNEITCLQEVIEQKEVEERQRECMLAASERSNDI 1667
Q+ + K+ E A +L + N + LQ IE+ + E + + + +E +
Sbjct: 324 KSQI-IEFQKIIESLKAENAKLQTENTNTVDKLQSEIEKLKQENSELQNQIQENEDGWND 382
Query: 1666 NVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLRE 1487
N N E L+N +++L ++ + + EE+ + L Q I++ ++
Sbjct: 383 NNNEEE------------LQNQITELQKQLEENKKSYSEETEQ------LKQIIDDDSKQ 424
Query: 1486 IRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQS 1307
I + K + EA+ + S + L+ K QL+ + L + D+A+
Sbjct: 425 IE-DLKQKLAEAQDHEGNSDSQLAKLQTEKQQLDKKLVDVANALRKLKTKNDNDQAT--- 480
Query: 1306 STGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKF 1127
+ N EN + KQ+EE K Q NN + AE+
Sbjct: 481 --------------------ISKLNEENSSLQ-KQIEELK--QQTANN--ASYEAEI--- 512
Query: 1126 LCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKEL 947
++ K +DL + + ++ E L+ E+ E N ++E +K++
Sbjct: 513 -----------QNLKKQLQDLQIQNDDIKTENEHLQQEMFENN-----KSEEIEQQKKQI 556
Query: 946 LIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQL------STKDT 785
+ E SK+ +++ K N I +L+++I+QI++ + L +L ++ D
Sbjct: 557 -----SELQKEISSKSSEIQAK--NDEIENLNKEIEQIKKENQELNEELFQNNENNSNDE 609
Query: 784 DMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQ----------IQEMLLN 635
+++ L Q+ Q+EIS + ++ +E L+ H ++ E L +
Sbjct: 610 EIEKLKTQIQSLQKEISDLSQQNNNYKSQVEELKEELEKHQSEQDENGWGEENESEELKS 669
Query: 634 QNVNY-----PLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIK 470
+N N L+ +N DQ +E +TED+ +EI K+ E +K
Sbjct: 670 ENENLKKQIEELKEQLNQKEDQGQEEN------GWCNENETEDLKSEIEQLK-KENETLK 722
Query: 469 LQSQVENLQSLVQMLKQQ 416
++ E+L+ ++ LK+Q
Sbjct: 723 QNNETESLKKQIEELKEQ 740
Score = 86.3 bits (212), Expect = 5e-14
Identities = 143/717 (19%), Positives = 304/717 (42%), Gaps = 38/717 (5%)
Frame = -2
Query: 2221 IQKEKNISEDLKETVKNLQSDL-------DIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
IQK + + +ET L ++L + ++KL D EI ++ +Q++
Sbjct: 47 IQKCSDALIEERETTATLTNELAECDKKIEEKEKLIEDLAKEIENMKNTTSTASQNDSGL 106
Query: 2062 LKRLKEAEQTLLEAESERESLK---AELEESISVLKQ-------ELSSARLQIESLEKEL 1913
+ ++E EQ + ESE +++K +EL++ I K+ E + + ++E+++ E
Sbjct: 107 EEVVQEFEQKIETLESENKTMKDQNSELQQQIQQYKELTDKLSTESTELQQKMENIKSED 166
Query: 1912 NQANEE-VKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVI 1736
A E ++ +S Q+ +L+E +Q + ++ +A ++ + +IT L+ +
Sbjct: 167 KSAEETLLQTISDQDIQINKLKEELEQAKLAANSSEQNTNAFAQKEQELNAQITDLKNQL 226
Query: 1735 EQKEVEERQRECMLAASERSNDINVNALE-----KKLSAYEGKIRRLENDVSQLTLSVDF 1571
K+ + + A N N + E K S + +D+S+L +V
Sbjct: 227 AAKDSLSDEIASLKAQIAELNQNNSKSSEENEQLKAESQKDASSDDKNSDLSRLKKAVVQ 286
Query: 1570 SAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQ 1391
++ ++++ +++NF E + V I++ + + EF +++ L+ ++
Sbjct: 287 LKKQIAQKDQEINDLKTSNMQLQNFNNETQ---NVEIEKYKSQIIEFQKIIESLKAENAK 343
Query: 1390 LETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECK 1211
L+T NT D L S + ++ + Q+ +N+ + L+N+ +
Sbjct: 344 LQTENTNTVDKLQSEIEKLKQENSELQNQIQENE--------DGWNDNNNEEELQNQITE 395
Query: 1210 -SKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNH-GQLRA 1037
KQ+EE K +E L + + K + + LK K +H G +
Sbjct: 396 LQKQLEENKKSYSEETEQLKQIIDDDSKQI-----------EDLKQKLAEAQDHEGNSDS 444
Query: 1036 EMSSLKIELVEKNGFMGYAVLDVENVQKELLIW--KDRAMIA----EGQSKAFQL-ELKH 878
+++ L+ E + + ++DV N ++L D+A I+ E S Q+ ELK
Sbjct: 445 QLAKLQTEKQQ----LDKKLVDVANALRKLKTKNDNDQATISKLNEENSSLQKQIEELKQ 500
Query: 877 ANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQL--TLAQEEISSTKEMLKDFI 704
+ S +IQ ++++ + L Q T+ +HL ++ EEI K+ + +
Sbjct: 501 QTANNASYEAEIQNLKKQLQDLQIQNDDIKTENEHLQQEMFENNKSEEIEQQKKQISELQ 560
Query: 703 DNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTE 524
+ + + +Q+ ++I +N+N +E K+ +
Sbjct: 561 KEISSKSSEIQAKNDEI------ENLNKEIEQI----------------------KKENQ 592
Query: 523 DINTEIAHTSD---KDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEKYFH 353
++N E+ ++ DEE+ KL++Q+++LQ + L QQN + + E+ E H
Sbjct: 593 ELNEELFQNNENNSNDEEIEKLKTQIQSLQKEISDLSQQNNNYK---SQVEELKEELEKH 649
Query: 352 FEELCQSLVXXXXXXXXXXXXXXXKNQVLVKQVKEMQVTL-QSESPMEGETDSISEN 185
E ++ +N+ L KQ++E++ L Q E + E +EN
Sbjct: 650 QSEQDEN----GWGEENESEELKSENENLKKQIEELKEQLNQKEDQGQEENGWCNEN 702
Score = 83.6 bits (205), Expect = 3e-13
Identities = 148/667 (22%), Positives = 268/667 (40%), Gaps = 40/667 (5%)
Frame = -2
Query: 2221 IQKE-KNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
I+KE + ++E+L + +N +D +IE KL T +I SL E+ ++Q +++E
Sbjct: 587 IKKENQELNEELFQNNENNSNDEEIE-KLKT----QIQSLQKEISDLSQQNNNYKSQVEE 641
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKF--R 1871
++ L + +SE++ E LK E + + QIE L+++LNQ ++ + + +
Sbjct: 642 LKEELEKHQSEQDENGWGEENESEELKSENENLKKQIEELKEQLNQKEDQGQEENGWCNE 701
Query: 1870 YQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECMLA 1691
+ +L+ +QL + + ++ + K +I L+E ++QKE ++ Q E
Sbjct: 702 NETEDLKSEIEQLKKENETLKQN-----NETESLKKQIEELKEQLKQKE-DQGQEENGWG 755
Query: 1690 ASERSNDI--NVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVS--NAC 1523
+ D ++ALE + KI+ L N + L + KE + + N+
Sbjct: 756 EENETEDYKSQISALENEKRTLNKKIKDLANGLKTLKSKNEKLEQQLKENANNGNNDNSK 815
Query: 1522 DLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTH 1343
D+ E N E E + +E R N E S K L ++L + N D +S+
Sbjct: 816 DISVEF-NETEEKITELEFENEELRRNNESLSEEKKTLHKQNNKLVSENKTLSDEVSTLR 874
Query: 1342 QGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNN 1163
+ +E+ ST + E E +S+ + + L+ NN
Sbjct: 875 E-QVEELEEETISTSN------------------ELRSEIEHLRSELVVREQELEQTKNN 915
Query: 1162 WLSCMNAEMGKFLCLCNSMVYLEG--------DILKYKEDLLLNHGQLRAEMSSLKIEL- 1010
+ N E + +Y E + LK + N+ +L E SLK E+
Sbjct: 916 NNNVNNNENNNSNVHSDQSIYEEKISLLKQQLEELKQSQSSNNNNEELEKENISLKKEIE 975
Query: 1009 --------VEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELK--------- 881
++ F G + N +KE I K ++ I E + K E
Sbjct: 976 DLKQENEGLQNQLFEGGETNENNNQEKEDEIHKLKSEIEELKKKLESSEQNKEEENNGWG 1035
Query: 880 HANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKD--F 707
N ++ +IEE K L + + D + + EE+ E L+ F
Sbjct: 1036 DENTETENIDNLKSEIEELNKKLDESIKSNDEKQKKI--------EEMKQENEELQTQLF 1087
Query: 706 IDNMEASDTNLQSHFNQIQEMLLNQN-VNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKD 530
+N E +S ++ + L N N L++ ++ D + K+
Sbjct: 1088 ENNSEEEINKFKSQVEELTQKLQESNQKNEELQSQTEKQNNEIDDLKKQKEEENEKLQKE 1147
Query: 529 TEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTK----LELLAKKTSEMDPEK 362
D+ EI+ K+EE +LQ +++LKQ N K +E LAK+ E+ EK
Sbjct: 1148 ISDLKNEISQLQQKEEE------NGSDLQKQIEVLKQTNEKNDEDIEQLAKQIDELQTEK 1201
Query: 361 YFHFEEL 341
EE+
Sbjct: 1202 EKQNEEI 1208
Score = 80.9 bits (198), Expect = 2e-12
Identities = 139/673 (20%), Positives = 286/673 (42%), Gaps = 53/673 (7%)
Frame = -2
Query: 2233 VRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQ-------- 2078
++ + +K+KN +DLK+ + LQ+ L E + +++ EI+ L +E+E + +
Sbjct: 1221 IKSENEKQKNEIDDLKKENEELQTQL-FEIGNNQEKEEEIHKLKSEIEELKKKLEESEQN 1279
Query: 2077 SEQMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELN---Q 1907
E+ ++ LK +TL E ES +L++ S L+QE S Q +S E+E N +
Sbjct: 1280 KEEENIDNLKSENETLKEEIKRLESDNEQLKKQNSELQQENKSLHQQ-QSKEEEENGWGE 1338
Query: 1906 ANEEVKVLSKFRYQVLELEEYSQQLSADLSKVH-----------EDYSAALRQLFDKK-- 1766
NE ++ S+ ++EE +QL + EDY + + L ++K
Sbjct: 1339 ENESEELKSENESLKKQIEELKEQLKQKEDQGQEENGWGDENETEDYKSQISALENEKRT 1398
Query: 1765 ---------NEITCLQEVIEQKEVEERQRECMLAASERSNDINV--NALEKKLSAYE--- 1628
N + L+ E+ E + + + ++ S DI+V N E+K++ E
Sbjct: 1399 LNKKIKDLANGLKTLKSKNEKLEQQLKDINSNNSTNDNSKDISVEFNETEEKITELEFEN 1458
Query: 1627 GKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEAR 1448
++RR +S+ ++ E+ +S+ L+E + E+ ET T E R
Sbjct: 1459 EELRRNNESLSEEKKTLQKQNNKLVSENKTLSDEVSTLRE---QVEELEEETISTSNELR 1515
Query: 1447 HNVEEFSS--VVKHLEYLKSQLETSNTMDHDTLSS---THQGSMEDKASSQSSTGDNDPK 1283
+E S V++ E +++ +N +++ +S + Q E+K S +
Sbjct: 1516 SEIEHLRSELVLREQELEQTKNNNNNVNNNENNNSNVHSDQSIYEEKISLLKQ------Q 1569
Query: 1282 AXXXXXXXXXXXECRQNLENEECK--SKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNS 1109
+ N +++E K++E+ K EL N L E + N+
Sbjct: 1570 LEELKQQQQKPFDHEDNNDSDEINKLKKEIEDLKQENEELQNQL-FEGGETNE-----NN 1623
Query: 1108 MVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDR 929
E +I K K ++ +L+ ++ S + E+N G + EN++
Sbjct: 1624 NQEKEDEIHKLKSEI----EELKKKLESSEQNKEEENNGWGDENTETENIEN-------- 1671
Query: 928 AMIAEGQSKAFQLELKHANMSICSLS----EKIQQIEEREKVLLTQLSTKDTD---MQHL 770
+ E++ N + LS EK ++IEE E+ L + KD + ++ L
Sbjct: 1672 ----------LKSEIEELNKKLNELSKSNDEKQKKIEELEQKLQESQNNKDEEEENIEDL 1721
Query: 769 AAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGF 590
QL + + + + ++ I+N++ ++ +I E L + +A +
Sbjct: 1722 KEQLEQLRRDAITKSKQDQEEIENLKKQIEEKEADIEEITEELEQLRKDSITKAKQD--- 1778
Query: 589 DQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENL-QSLVQMLKQQN 413
+ +++ +EI Q + +++N EI +K+ E L+ +++ L + +Q K
Sbjct: 1779 QEEIEKLQNEIQKQ---KEIIDNLNAEIDELGEKEAEHEDLKDELQQLRKDSLQKAKIDQ 1835
Query: 412 TKLELLAKKTSEM 374
+++ L + S +
Sbjct: 1836 AEIDRLNAEVSNL 1848
Score = 79.7 bits (195), Expect = 5e-12
Identities = 139/686 (20%), Positives = 274/686 (39%), Gaps = 66/686 (9%)
Frame = -2
Query: 2218 QKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAE 2039
+K + + L+E + Q D E +D EI L E+E + Q + +L E
Sbjct: 1561 EKISLLKQQLEELKQQQQKPFDHEDNNDSD---EINKLKKEIEDLKQENEELQNQLFEGG 1617
Query: 2038 QTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQVL 1859
+T E+E +L+ I LK++L S+ E N E + + + ++
Sbjct: 1618 ETNENNNQEKEDEIHKLKSEIEELKKKLESSEQNKEEENNGWGDENTETENIENLKSEIE 1677
Query: 1858 ELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQ-KEVEERQRECMLAASE 1682
EL + +LS + + ++L + +N +E IE KE E+ R + S+
Sbjct: 1678 ELNKKLNELSKSNDEKQKKIEELEQKLQESQNNKDEEEENIEDLKEQLEQLRRDAITKSK 1737
Query: 1681 RSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEI- 1505
+ + + L+K++ E I + ++ QL A +EE K+ N +EI
Sbjct: 1738 QDQE-EIENLKKQIEEKEADIEEITEELEQLRKDSITKAKQDQEEIEKLQNEIQKQKEII 1796
Query: 1504 -----------------ENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLET-- 1382
E+ E++ K ++Q+A+ + E + + LK +LE
Sbjct: 1797 DNLNAEIDELGEKEAEHEDLKDELQQLRKDSLQKAKIDQAEIDRLNAEVSNLKFELENGK 1856
Query: 1381 SNTMDHDTLSSTH-----------QGSMEDKAS-----SQSSTGDNDP---KAXXXXXXX 1259
N D + H + +EDK S + + DP K
Sbjct: 1857 ENIWGDDDDNEKHKETLTEIIEKLKSEIEDKNSEIEKLEEEISQFEDPTEVKQENKKLKE 1916
Query: 1258 XXXXECRQNLE----NEE------------------CKSKQMEEYKMLQAELNNWLSCMN 1145
RQN E NEE K+++E + +L++ L+ +
Sbjct: 1917 ELDQALRQNAELGNVNEENNKLREQLKQSIDTNELKTLEKKLKEKEEENQKLHDDLNTLQ 1976
Query: 1144 AEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVE 965
E+ + + E ++ + + L N + ++S L +L E+ F+ V +E
Sbjct: 1977 FELNNSIAGLPKINQSESMEIRDEVERLANENK---KLSELTKKLEEEKNFL---VSQLE 2030
Query: 964 NVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDT 785
NV + K+ + E +L+LK A L ++I ++ E+ + + S ++
Sbjct: 2031 NVVQRNDYEKELQNVEE-----LKLKLKKAEKDNEELLQQIDELVEQNETENHEKSDAES 2085
Query: 784 DMQHLAAQLTL---AQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPL 614
+++ L A+L +++E +E + + +E S+T N+ + +++QN
Sbjct: 2086 ELKSLKAELAKLKDSEKEYQVLREEVDELTQKIEESET-----INKELKTIIDQNDTSAA 2140
Query: 613 EATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLV 434
E FD+ + VS++ Q ED+ + + + +E+ KL + L + +
Sbjct: 2141 ENMYKAQFDE-LKALVSDLKSQ------NEDLKKD---SENSKQEITKLTEEKTELNANI 2190
Query: 433 QMLKQQNTKLEL-LAKKTSEMDPEKY 359
+ L Q N+ L + K T+E+ K+
Sbjct: 2191 EKLTQDNSNLSSNVEKLTNEISNLKF 2216
>ref|XP_006819694.1| PREDICTED: nuclear anchorage protein 1-like [Saccoglossus
kowalevskii]
Length = 4661
Score = 106 bits (265), Expect = 4e-20
Identities = 143/674 (21%), Positives = 310/674 (45%), Gaps = 52/674 (7%)
Frame = -2
Query: 2227 LDIQKEKNISEDLK--ETVKNLQSDLDIEQKLSTDRQSE----IYSLSAELERITQ---- 2078
LD+ ++K + D E + L+ + ++K S +Q E I L++E+E++ Q
Sbjct: 1342 LDLLQQKLVETDSNSAEKISELEQQVSEKEKRSLLQQEENNESITKLNSEMEKLQQQFQE 1401
Query: 2077 ------SEQMSLKRLK---EAEQTLLEAESER-ESLKAELEESISVL---KQELSSARLQ 1937
S++ KRL+ + ++TLL+++ + E L+ ++E + L ++E++
Sbjct: 1402 ERSQLHSQERETKRLQHDLQEKETLLQSQEKGVEELQLRIQEKENQLQCEREEVALLHQN 1461
Query: 1936 IESLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI 1757
+E E+ L EEV L + ++LE E Q +++K+ + QL +K+N +
Sbjct: 1462 LEEKEEVLLSQREEVDTLHR---EILEKESMLQSQKGEIAKLQQ-------QLIEKENML 1511
Query: 1756 TCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSV 1577
QE IEQ + + +++ +L +S + V+ ++ +L + ++ + ++ + +
Sbjct: 1512 CLQQEKIEQLQSQLQEKVTLL----QSQEDEVHRMQLELQEEQNMLQLQKEEIENVQKKL 1567
Query: 1576 DFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLK 1397
+ + + N LQE +N L + E V +QE + E S++ K + +
Sbjct: 1568 IEKESLLEAGKHCIENLEHQLQEKDNMLHSQKNEMDVVLQE---KLAELSTLQKEIVMQQ 1624
Query: 1396 SQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEE 1217
S ++ N D DTL + +ED S + R+
Sbjct: 1625 SLVDEKN-KDIDTLRKRAE-DLEDTILSADDSNST---------LQTQIQTLREERNESF 1673
Query: 1216 CKSKQM--------EEYKMLQAELN---NWLSCMNAEMGK----FLCLCNSMVYLEGDIL 1082
KSKQ+ ++ M+Q EL+ N +S + +++ K L L NS+ E D+
Sbjct: 1674 SKSKQLDANLQELQQQLTMVQKELSVAQNEISSLQSQLEKSENCVLMLNNSIAEKEEDMT 1733
Query: 1081 KYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSK 902
++K++ + ++ +M +L E ++K+ + ++EN Q + ++ ++ + +
Sbjct: 1734 RFKQERDAHDIKVAEDMQNLLDENLKKHQELQN---ELEN-QTQFMLQENATTEERHKQQ 1789
Query: 901 AFQL-ELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTK 725
++ LK + +C+ E +Q+ E + QL + + + Q+T+ ++ +
Sbjct: 1790 LCEIASLKKTSAEMCTEKEILQKTVEDNLQKIYQLQGEVKEKEEELGQITVLTHQLQAQN 1849
Query: 724 EMLKDFIDNMEASDTNLQSHFNQIQEMLLN-----QNVNYPL-EATVNIGFDQSMDEAVS 563
+ +MEA+++ ++SHFNQ++++ L +NV L +AT + ++E +
Sbjct: 1850 Q-------DMEAANSQIKSHFNQLEDLKLQTEERAKNVASELTQATAKVNL---LEEHLL 1899
Query: 562 EIAVQTFPNKDTE---DINTEIAHTSDKDEEVIKLQSQVENL----QSLVQMLKQQNTKL 404
E Q F N E + E + +K++EV K+ +Q+ + SL ++K++N +
Sbjct: 1900 E-QQQMFENTIGEMRNQLMDEKVNIEEKEKEVDKVHNQLMAVMVEKDSLNTVIKEKNDTV 1958
Query: 403 ELLAKKTSEMDPEK 362
E + + + EK
Sbjct: 1959 EEIRNQLKALITEK 1972
Score = 82.0 bits (201), Expect = 1e-12
Identities = 143/692 (20%), Positives = 288/692 (41%), Gaps = 57/692 (8%)
Frame = -2
Query: 2233 VRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKR 2054
++L++Q+E+N+ + KE ++N+Q L ++ L + I +L +L+ + + M +
Sbjct: 1542 MQLELQEEQNMLQLQKEEIENVQKKLIEKESLLEAGKHCIENLEHQLQ---EKDNMLHSQ 1598
Query: 2053 LKEAEQTLLEAESERESLKAEL---EESISVLKQELSSARLQIESLEKELNQANEEVKVL 1883
E + L E +E +L+ E+ + + +++ + R + E LE + A++ L
Sbjct: 1599 KNEMDVVLQEKLAELSTLQKEIVMQQSLVDEKNKDIDTLRKRAEDLEDTILSADDSNSTL 1658
Query: 1882 ----SKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKE--- 1724
R + E S+QL A+L ++ + + ++L +NEI+ LQ +E+ E
Sbjct: 1659 QTQIQTLREERNESFSKSKQLDANLQELQQQLTMVQKELSVAQNEISSLQSQLEKSENCV 1718
Query: 1723 ------VEERQRECMLAASER-SNDINV-----NALEKKLSAYEGKIRRLENDVSQLTLS 1580
+ E++ + ER ++DI V N L++ L ++ LEN +Q L
Sbjct: 1719 LMLNNSIAEKEEDMTRFKQERDAHDIKVAEDMQNLLDENLKKHQELQNELENQ-TQFMLQ 1777
Query: 1579 VDFSA-----------GVFKEESTKVSNACDLLQE-IENFLREIRVETKVTIQEARHNVE 1436
+ + K+ S ++ ++LQ+ +E+ L++I + + ++E +
Sbjct: 1778 ENATTEERHKQQLCEIASLKKTSAEMCTEKEILQKTVEDNLQKI-YQLQGEVKEKEEELG 1836
Query: 1435 EFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXX 1256
+ + + L+ +E +N+ +H +ED N
Sbjct: 1837 QITVLTHQLQAQNQDMEAANSQ-----IKSHFNQLEDLKLQTEERAKN------------ 1879
Query: 1255 XXXECRQNLENEECKSKQMEEYKMLQAEL-NNWLSCMNAEMGKFLCLCNSMVYLEGDILK 1079
L K +EE+ + Q ++ N + M N ++ + +I +
Sbjct: 1880 ----VASELTQATAKVNLLEEHLLEQQQMFENTIGEMR----------NQLMDEKVNIEE 1925
Query: 1078 YKEDLLLNHGQLRA---EMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQ 908
++++ H QL A E SL + EKN V ++ N K L+ K+ + A +
Sbjct: 1926 KEKEVDKVHNQLMAVMVEKDSLNTVIKEKND----TVEEIRNQLKALITEKEN-LSAILE 1980
Query: 907 SKAFQLELKHANMSICSLSEK---IQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEI 737
K ++E KH N + + SEK I I+E+ +V + Q++ + ++ QL E +
Sbjct: 1981 EKVQEIEHKH-NEVLSATSEKESLIVTIQEKNEV-IKQMNKLIEEKEYTIEQLKKQLEFL 2038
Query: 736 SSTKEMLKDFIDNME--------------ASDTNLQSHFNQIQEMLLNQNVN-YPLEATV 602
S KE L+ +D E A N+ + Q+M+ N + E+ +
Sbjct: 2039 ESEKEGLERSVDEKEQLIDQMQNQLISSVAEKENMHIMIEEKQKMIALIETNAHECESNL 2098
Query: 601 NIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEV-IKLQSQVENLQSLVQML 425
N Q +E A+ + E++ ++ + E+ +LQS V L+ L
Sbjct: 2099 NDKCKQLTNELTGTNAMLQEVSNGKENLEVQLQEMQNSVEDFRRRLQSNVNELEERTSQL 2158
Query: 424 KQQNTKLELLAKKTSEMDPEKYFHFEELCQSL 329
QQ + LA + + + H E Q L
Sbjct: 2159 NQQIQINQDLAAQIERQENDIKNHKEAASQML 2190
Score = 78.2 bits (191), Expect = 1e-11
Identities = 126/658 (19%), Positives = 272/658 (41%), Gaps = 50/658 (7%)
Frame = -2
Query: 2188 KETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTLLEAES-- 2015
+ T+ +++ L E+ +++ E+ + +L + + +KE T+ E +
Sbjct: 1906 ENTIGEMRNQLMDEKVNIEEKEKEVDKVHNQLMAVMVEKDSLNTVIKEKNDTVEEIRNQL 1965
Query: 2014 -----ERESLKAELEESISVLK---QELSSARLQIESLEKELNQANEEVKVLSKFRYQVL 1859
E+E+L A LEE + ++ E+ SA + ESL + + NE +K ++K ++
Sbjct: 1966 KALITEKENLSAILEEKVQEIEHKHNEVLSATSEKESLIVTIQEKNEVIKQMNK----LI 2021
Query: 1858 ELEEYS-QQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECMLAASE 1682
E +EY+ +QL L + E L + D+K ++ +++ Q + + + +E
Sbjct: 2022 EEKEYTIEQLKKQLEFL-ESEKEGLERSVDEKEQL-----------IDQMQNQLISSVAE 2069
Query: 1681 RSN-DINVNALEKKLSAYEGKIRRLENDVS----QLTLSVDFSAGVFKEESTKVSNACDL 1517
+ N I + +K ++ E E++++ QLT + + + +E S N
Sbjct: 2070 KENMHIMIEEKQKMIALIETNAHECESNLNDKCKQLTNELTGTNAMLQEVSNGKENLEVQ 2129
Query: 1516 LQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQG 1337
LQE++N + + R + + E + + ++ + L +Q+E + + Q
Sbjct: 2130 LQEMQNSVEDFRRRLQSNVNELEERTSQLNQQIQINQDLAAQIERQENDIKNHKEAASQM 2189
Query: 1336 SMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWL 1157
+ + +Q +N+ K + ++ + E S + E + L LNN L
Sbjct: 2190 LNQIETLNQDIAINNEKKQSLARDVESFTFQLQEKNKVIEMLSHEGSEKESL---LNNEL 2246
Query: 1156 SCMN---AEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSL------KIELVE 1004
S A++ K L M+ + ++++ E+ + + E+ + + + +E
Sbjct: 2247 SIAQAKAAQLDKDLAATTEMMMNKMEVIQQLEEEIRGKERKMIELEDILQKKNEECDRIE 2306
Query: 1003 KNGFMGYAVLDVENVQKEL--LIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIE 830
N + A LD EN L I + M+ + Q + + +++I+
Sbjct: 2307 TN--LKQANLDHENTVLRLNTEITEKTTMVEQQQGQ---------------IESLVKEID 2349
Query: 829 EREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKE-----------MLKDFIDNMEASD 683
E + +L + +TK T++ L +L ++ I + K + K F + E
Sbjct: 2350 EIQNMLQEEENTKQTEIHSLNEELQVSMSAIQTLKSEATEKQNIVIAIEKQFQEREEHFQ 2409
Query: 682 TNLQSHFNQIQEM---LLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINT 512
+ + +H +I E L ++ F+ + E+ EI K ED+
Sbjct: 2410 SEMMAHETKIVEYEHELTELREGLSIKENEKCQFEHQLSESQKEI------GKLEEDLRE 2463
Query: 511 EIAHTSDKDE----EVIKLQSQVENLQS-----LVQMLKQQNTKLELLAKKTSEMDPE 365
E HTS D+ E+ Q ++ QS + +++++ + E AK S+ D +
Sbjct: 2464 EKHHTSKLDDELKHELAATQQSSDHQQSEQSGHVARLVEELSQLRESTAKDISQYDEQ 2521
Score = 77.8 bits (190), Expect = 2e-11
Identities = 118/641 (18%), Positives = 250/641 (39%), Gaps = 29/641 (4%)
Frame = -2
Query: 2209 KNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTL 2030
+N + K+ V NLQ+ + + + + SE+ L L+ + + + + ++L + Q L
Sbjct: 884 ENSLRERKQEVDNLQTAVITQNETAESTASEVDILKKTLQELERHKATNEEQLAKLGQEL 943
Query: 2029 LEAESERESLKAELEESISVL-----------------KQELSSARLQIESLEKELNQAN 1901
+ +E+ L +L E +L + + ++ L+ +L
Sbjct: 944 SDITTEKGHLDEKLVEKQHILVDTAEKLRQREMEATTWAENFAGKETEVAELQVQLGSVQ 1003
Query: 1900 EEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQ--K 1727
E+VK ++ +LELE L ++L + ++ + K+E + +IEQ K
Sbjct: 1004 EKVKNMNT---HILELENALDTLQSELDEANKSIEDERNRFNGDKSE---YERIIEQQNK 1057
Query: 1726 EVEERQRECMLAASERSNDIN-VNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
++EE R ND N + L++ + E ++++ +N + + + F+E
Sbjct: 1058 DIEELH-------LARKNDSNAADELKENVRLLESEVQKQKNQFEKKVQDIQHLSQEFQE 1110
Query: 1549 ESTKVSNA---CDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETS 1379
K+S+ ++LQE ++ + ++VE+K+T S+++ + ++ +L
Sbjct: 1111 LELKMSSTNREIEVLQESQS-VEGVKVESKIT------------SLLEQISDIEKELMQQ 1157
Query: 1378 NTMDHD------TLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEE 1217
+HD L++ H +K Q D K + +E
Sbjct: 1158 QNRNHDQEQVIAKLNTDH-----EKLQQQLHERDTQLKGVQEQLIHTLQLVQDKETGYQE 1212
Query: 1216 CKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRA 1037
EEY+ L+ ++ + +E+G C ++ Q+R
Sbjct: 1213 QLKTAKEEYQSLEDNNKEHVNNLASEIGTLTAGCENL-------------------QIRL 1253
Query: 1036 EMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICS 857
E + +E+ +KE D +M I
Sbjct: 1254 E------------------EMQMEHAKKE-----DASM-----------------QEINQ 1273
Query: 856 LSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTN 677
L +K++Q +E+ + +L + ST QL Q++++S + L D + + N
Sbjct: 1274 LQQKLKQEQEKHQAMLNRSST----------QLLSLQDDLTSVSKQLDDERKHFNNKEGN 1323
Query: 676 LQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHT 497
L S + +QE L + L + D + E +SE+ Q +E +
Sbjct: 1324 LLSELDSLQEKLSMSQKDLDLLQQKLVETDSNSAEKISELEQQV-----SEKEKRSLLQQ 1378
Query: 496 SDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEM 374
+ +E + KL S++E LQ Q +++ ++L ++T +
Sbjct: 1379 EENNESITKLNSEMEKLQ---QQFQEERSQLHSQERETKRL 1416
Score = 77.4 bits (189), Expect = 2e-11
Identities = 119/598 (19%), Positives = 251/598 (41%), Gaps = 33/598 (5%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSL 2060
D + I E ++++ KNL +D ++E K S+D ++ + EL +I + + +
Sbjct: 2769 DLTQKVIDNEIQFVQEIENLKKNL-NDKEVELKRSSDEENNLAQRVNELNKIIEEKDQCI 2827
Query: 2059 KRLKEAEQTLLEAESERESLKAELEESISVLK-------QELS----SARLQIESLEKEL 1913
K+L E L + E+ ESL +L E LK QEL +A ++ + LE +L
Sbjct: 2828 KKL---EVVLEDNENMMESLSVQLHEKDKKLKELIEKQEQELQDFQDAAAVKKKQLEDQL 2884
Query: 1912 NQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIE 1733
Q E+ + + ++ +E+Y+QQL +L H L+ F + T Q+ ++
Sbjct: 2885 QQYEEKELTHASLQEKLDCVEQYNQQLRDELQTKHFTVE-KLQHNFQESE--TSWQKEMQ 2941
Query: 1732 QKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFK 1553
+ E E +E ++ ++ +L + + + + LE+++ Q +++
Sbjct: 2942 KAEKEHSYKETIIQQELKTLQEKHKSLNETMQSKNQLLETLEHELQQTKEAMESLKQQQA 3001
Query: 1552 EESTKVSNACDLLQEIENFLRE-----------IRVETKVTIQEARHNVEEFSSVVKHLE 1406
++ + N + L+ I+ L E I++ +E + E + + +E
Sbjct: 3002 DQDEIIKNEKEDLKMIQQNLSEKETLCDELTNQIQMLESEQSKETQSYREAYENSFSKIE 3061
Query: 1405 YLKSQLETSNTM-----DHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXEC 1241
++ Q++ N M + T T ++ + + S + + +
Sbjct: 3062 EMEMQVQAKNEMIEILKEQLTEKETDLVTLGTSFTEKDSKVEELTHSFSALQATLDEEKE 3121
Query: 1240 RQNLENEECK---SKQMEEYKMLQAEL---NNWLSCMNAEMGKFLCLCNSMVYLEGDILK 1079
+ +E E + +K +E+ K L+A+L + + +N E+ S+ ++G
Sbjct: 3122 KHGIEIENIRKRYAKLLEKAKELKAKLELSSREKNALNDEI-------ESLKKMQG---- 3170
Query: 1078 YKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKA 899
ED + H L+ E+ SL+ E+ EKN + +V + E++ K+ A + E ++
Sbjct: 3171 -TEDEV--HIHLKQEVESLRKEVWEKNEKVLSLKDNVSKFENEIIKQKEFAELKEQEASK 3227
Query: 898 FQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEM 719
+Q L+ N I L I ER + ++ + ++ + ++ Q+ KE
Sbjct: 3228 YQDNLEKLNEQIVILQNNISSQTERADISDKKVIKQQEVIKEQSESISKLQKGFVLLKEK 3287
Query: 718 LKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQT 545
+K ++ L+ +I+E L Q ++ E + D A+ E QT
Sbjct: 3288 VKSQRSEIQELKETLKMQVEKIEE--LQQELDNEREIVKKVSDDLKEHVAIKEELEQT 3343
Score = 67.0 bits (162), Expect = 3e-08
Identities = 137/650 (21%), Positives = 262/650 (40%), Gaps = 45/650 (6%)
Frame = -2
Query: 2194 DLKETVKNLQSDLD------IEQKLSTDRQSEIYS-----LSAELERITQSEQMSLKRLK 2048
+L+ + Q +LD IE +++ Q + S L EL+ Q+ + K LK
Sbjct: 521 ELESLLHQTQGELDQSKQRLIELDSASESQHHVQSEELDKLRTELKEKEQTIKDLSKSLK 580
Query: 2047 EAEQTLLEAESERESLKAELEESISVLKQ------ELSSARLQIESLEKELNQANEEVKV 1886
E E +L+A++ + LE + LKQ E+S + QI LE E Q ++
Sbjct: 581 ETETKVLKAKAHSKKRMRNLETELEQLKQSDSLAEEVSGLQHQIAELEDEKGQLQLKLVD 640
Query: 1885 LSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQR 1706
+ +++EL++ L+ + ++ + S L+Q +K+N + E+ E R
Sbjct: 641 FDEMNIKLVELQDTIDLLTQEKQELIQSVS-ELKQ--EKENNDATIHEL----EDRIRMM 693
Query: 1705 ECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNA 1526
E + SE + +E +I +++ + QL D E +VS
Sbjct: 694 EATFSQSEEDQKLE----------HEARIHEMKSMMEQLREEKD------TERKARVSFE 737
Query: 1525 CDLLQEIENFLR--EIRVETK-VTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTL 1355
+L E+E R E +E++ TI + N+E+ S ++K ++ ET+ ++ D +
Sbjct: 738 ARIL-ELEEIQRRNEFSLESQNQTITAMKDNLEKLSEMLKEVQ------ETNTCIEQDKV 790
Query: 1354 SSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQA 1175
+ + ++ ++ K E R E E + + M E LQ
Sbjct: 791 TLELRLVQIEEEKDGLEREKHELKEEVQSLNSKIENEHRPLFEIENERKQYMNEITSLQQ 850
Query: 1174 ELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNG 995
LN+ + K L +E ++L K ++ + + + E+ +L+ ++ +N
Sbjct: 851 GLND---IQQSHQQKEELLRQKEERIE-ELLSNKIEIENSLRERKQEVDNLQTAVITQNE 906
Query: 994 FMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKI--------- 842
+V+ ++K L + E Q EL L EK+
Sbjct: 907 TAESTASEVDILKKTLQELERHKATNEEQLAKLGQELSDITTEKGHLDEKLVEKQHILVD 966
Query: 841 --QQIEEREKVLLT---QLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTN 677
+++ +RE T + K+T++ L QL QE++ K M ++ A DT
Sbjct: 967 TAEKLRQREMEATTWAENFAGKETEVAELQVQLGSVQEKV---KNMNTHILELENALDT- 1022
Query: 676 LQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHT 497
LQS ++ + + ++ + D+S E + E NKD E+++ +
Sbjct: 1023 LQSELDEANKSIEDERNRF--------NGDKSEYERIIE-----QQNKDIEELHLARKND 1069
Query: 496 SDK-----------DEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTS 380
S+ + EV K ++Q E +Q L Q+ +LEL T+
Sbjct: 1070 SNAADELKENVRLLESEVQKQKNQFEKKVQDIQHLSQEFQELELKMSSTN 1119
Score = 66.6 bits (161), Expect = 4e-08
Identities = 133/676 (19%), Positives = 268/676 (39%), Gaps = 42/676 (6%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
++ +++ Q + + + + + L DL Q T +Q E Y A++E++ QS
Sbjct: 2601 VEELKIAQQNTEQVQDMYAQQIAKLTQDLAGTQD-DTKKQHENYI--AQIEKLNQSLAER 2657
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEV--K 1889
++ +Q ++ S ++SL ++ I L++E+S R + + +EL + E + +
Sbjct: 2658 EHIIENIQQ---QSSSSQQSLLEVHKQEIVKLQEEVSETRHTLSGITQELQEGQERLIHE 2714
Query: 1888 VLSKFRYQV---------LELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVI 1736
+ +KF+ Q LE + +L ++ +H L DK I L + +
Sbjct: 2715 IDAKFQLQEELGRVEAEKANLESNTMELQESITLLHSKLEEIQTHLHDKNEIIEDLTQKV 2774
Query: 1735 EQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVF 1556
E++ Q + L+K L+ E +++R ++ + L V+ +
Sbjct: 2775 IDNEIQFVQE--------------IENLKKNLNDKEVELKRSSDEENNLAQRVNELNKII 2820
Query: 1555 KEESTKVSNACDLLQEIENFLREIRVET-------KVTIQEARHNVEEFSSVVKHLEYLK 1397
+E+ + +L++ EN + + V+ K I++ +++F K
Sbjct: 2821 EEKDQCIKKLEVVLEDNENMMESLSVQLHEKDKKLKELIEKQEQELQDFQDAA---AVKK 2877
Query: 1396 SQLETSNTMDHDTLSSTHQGSMEDKAS-----SQSSTGDNDPKAXXXXXXXXXXXECRQN 1232
QLE ++ TH S+++K +Q + K E +
Sbjct: 2878 KQLE-DQLQQYEEKELTH-ASLQEKLDCVEQYNQQLRDELQTKHFTVEKLQHNFQESETS 2935
Query: 1231 LENEECKSKQMEEYK--MLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLL 1058
+ E K+++ YK ++Q EL E K L N + + +L+ E L
Sbjct: 2936 WQKEMQKAEKEHSYKETIIQQELKTL-----QEKHKSL---NETMQSKNQLLETLEHEL- 2986
Query: 1057 NHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELL--------IWKDRAMIAEGQSK 902
Q + M SLK + +++ + D++ +Q+ L + M+ QSK
Sbjct: 2987 --QQTKEAMESLKQQQADQDEIIKNEKEDLKMIQQNLSEKETLCDELTNQIQMLESEQSK 3044
Query: 901 AFQLELKHANMSICSLSEKIQQIE---EREKVLLTQLSTKDTDMQHLAAQLTLAQEEISS 731
Q + S + E Q++ E ++L QL+ K+TD+ L T E+ S
Sbjct: 3045 ETQSYREAYENSFSKIEEMEMQVQAKNEMIEILKEQLTEKETDLVTLGTSFT---EKDSK 3101
Query: 730 TKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAV 551
+E+ F D + H +I+ + + + +++A A
Sbjct: 3102 VEELTHSFSALQATLDEEKEKHGIEIE--------------NIRKRYAKLLEKAKELKAK 3147
Query: 550 QTFPNKDTEDINTEIAH----TSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKT 383
+++ +N EI +DE I L+ +VE+L+ V ++N K+ L
Sbjct: 3148 LELSSREKNALNDEIESLKKMQGTEDEVHIHLKQEVESLRKEVW---EKNEKVLSLKDNV 3204
Query: 382 SEMDPE--KYFHFEEL 341
S+ + E K F EL
Sbjct: 3205 SKFENEIIKQKEFAEL 3220
Score = 64.7 bits (156), Expect = 2e-07
Identities = 140/689 (20%), Positives = 297/689 (43%), Gaps = 72/689 (10%)
Frame = -2
Query: 2221 IQKEK-NISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAE-LERITQSEQMSLKRL- 2051
+Q EK N+ E+L++ V+ ++D I + +T ++E + E L+R LK+L
Sbjct: 3445 LQHEKDNVDEELRKLVQ--ETDRQIVELEATRSENEHMKTNLETLQREKDVMDEELKKLV 3502
Query: 2050 ---KEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQANEEVK 1889
+ ++ L A +E E K E E E +E++ ++ +++ E E +K
Sbjct: 3503 QETDQQQEDLEAARNESEHWKTEFEKKQEEFLETHEEITRVMGELATMQMEKADEEERLK 3562
Query: 1888 VLSKFRYQVLE-LEEYSQQLSADLSKVHEDYSAALR-QLFDKKNEITCLQEVIEQKE--V 1721
+ ++ ++E ++QLS D+++ ++ Q+ ++ E L++ +E E +
Sbjct: 3563 AIQLSSASSMDSVQEMTRQLS-DMTEAKQELEQTFNAQIKERTMECENLKKSLEDAENII 3621
Query: 1720 EERQRECMLAASERSNDINVNALEKKLSAYEGK---IRRLEN-DVSQLTLSVDFSAGVFK 1553
E Q + A E+ +I ++ S+ EG+ +++LE+ ++ L ++ SA + K
Sbjct: 3622 SELQTQ-KSAVMEQLKEIELS----NASSTEGQQEMVKQLEDVTTAKQNLEIESSATIEK 3676
Query: 1552 EESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLE-------YLKS 1394
ES + DL + ++++ +++ + + + H ++F + LE K+
Sbjct: 3677 LESACEALRNDL-ESGKSYINQLKSQVEELQKVKDHLKQQFDETLARLETAQLSEEQFKN 3735
Query: 1393 QLETSNTMDHDTLSSTHQGSMED-----KASSQSSTGDNDPKAXXXXXXXXXXXECRQNL 1229
QLET T + D +T Q + + SS+S D K + L
Sbjct: 3736 QLETL-TRERDEWHTTMQELKYEIENLRQNSSESVVETMDVKNELNVLRDKHRQTSDELL 3794
Query: 1228 ----ENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLL 1061
E E KS++ + L E ++W + M + L S ++ + K +L
Sbjct: 3795 AVKNELEALKSEKSNVAETLIKERDDWYTKMQESKYEIENLRQSSSDMDTETRNIKNELT 3854
Query: 1060 L---NHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQL 890
L H Q E+ K E+ V + +V+ ELL + ++++F
Sbjct: 3855 LLGEKHEQTLKELVIAKNEVSSVTEKFQIVVNECASVKDELLSVQQSCQDKGLKNESFMQ 3914
Query: 889 EL---KHANMSICSLSEKIQQ-----------IEEREKVLLTQLSTKDTDMQHLAAQLTL 752
EL K + +C ++K++Q ++ KV + + + ++Q + + L
Sbjct: 3915 ELTTLKDEHQQVCEENQKLKQKTTLYHTHLVKMKNELKVGKNENNQQQAELQKMKSLLER 3974
Query: 751 AQEEISSTKEMLKDFIDN-----------------MEASDTNLQ-SHFN-QIQEMLLNQN 629
EI S E +++ ++ E SD +++ H++ +I EM +
Sbjct: 3975 QNTEIKSQLEKIREDMEQKNIDTRDKYENEIARLRQELSDKDVEVEHYDAEIAEMKKDLT 4034
Query: 628 V--NYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQV 455
+ + LE G S+ +S++ D + I E++ ++ +E+ ++ Q
Sbjct: 4035 LIESEKLECVNETG---SLRRQLSDVG------SDRDTIAWELSSVKEELDELKLVEEQN 4085
Query: 454 ENLQSLVQMLKQQNTKLE-LLAKKTSEMD 371
L+ + ++K+QN +LE L ++ S+ D
Sbjct: 4086 RTLEKELNVVKEQNKELENRLQQELSDKD 4114
Score = 58.9 bits (141), Expect = 9e-06
Identities = 118/636 (18%), Positives = 254/636 (39%), Gaps = 28/636 (4%)
Frame = -2
Query: 2197 EDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTLLEAE 2018
++ E +K + ++ ++ + ++ L +E E + +S + + + + L+ +
Sbjct: 2008 QEKNEVIKQMNKLIEEKEYTIEQLKKQLEFLESEKEGLERSVDEKEQLIDQMQNQLISSV 2067
Query: 2017 SERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQVLELEEYSQ 1838
+E+E++ +EE ++ ++A +L + Q E L+ + E+ +
Sbjct: 2068 AEKENMHIMIEEKQKMIALIETNAHECESNLNDKCKQLTNE---LTGTNAMLQEVSNGKE 2124
Query: 1837 QLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVN 1658
L L ++ R+L NE+ EER S+ + I +N
Sbjct: 2125 NLEVQLQEMQNSVEDFRRRLQSNVNEL------------EER-------TSQLNQQIQIN 2165
Query: 1657 A-LEKKLSAYEGKIRRLENDVSQL-----TLSVDFSAGVFKEESTKVSNACDLLQEIENF 1496
L ++ E I+ + SQ+ TL+ D + K++S L +++E+F
Sbjct: 2166 QDLAAQIERQENDIKNHKEAASQMLNQIETLNQDIAINNEKKQS--------LARDVESF 2217
Query: 1495 LREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKAS 1316
+++ + KV I+ H E S++ + E +Q + + +D D L++T + M
Sbjct: 2218 TFQLQEKNKV-IEMLSHEGSEKESLLNN-ELSIAQAKAAQ-LDKD-LAATTEMMMNKMEV 2273
Query: 1315 SQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAEL-------NNWL 1157
Q + K R+ +E E+ K+ EE ++ L N +
Sbjct: 2274 IQQLEEEIRGKE-------------RKMIELEDILQKKNEECDRIETNLKQANLDHENTV 2320
Query: 1156 SCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAV 977
+N E+ + + +G I +++ L+ E ++ + E+ N + ++
Sbjct: 2321 LRLNTEITEKTTMVEQQ---QGQIESLVKEIDEIQNMLQEEENTKQTEIHSLNEELQVSM 2377
Query: 976 LDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLS 797
++ ++ E ++ I K FQ +H + + KI + E L LS
Sbjct: 2378 SAIQTLKSEA---TEKQNIVIAIEKQFQEREEHFQSEMMAHETKIVEYEHELTELREGLS 2434
Query: 796 TKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYP 617
K+ + QL+ +Q+EI +E L++ + D L+ Q+ +Q
Sbjct: 2435 IKENEKCQFEHQLSESQKEIGKLEEDLREEKHHTSKLDDELKHELAATQQSSDHQQ---- 2490
Query: 616 LEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDK---------------DE 482
+ G + E +S++ T KD + ++A S++ E
Sbjct: 2491 ---SEQSGHVARLVEELSQLREST--AKDISQYDEQVAKLSEQLSATQERLQEKEDYYTE 2545
Query: 481 EVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEM 374
+VI+L ++ + Q KQQ+T +E +A+ T E+
Sbjct: 2546 QVIRLTEELTGMNE--QAKKQQDTYVEQIAELTKEL 2579
>ref|XP_002495471.1| ZYRO0B12144p [Zygosaccharomyces rouxii] gi|238938361|emb|CAR26538.1|
ZYRO0B12144p [Zygosaccharomyces rouxii]
Length = 2005
Score = 106 bits (264), Expect = 5e-20
Identities = 155/678 (22%), Positives = 291/678 (42%), Gaps = 46/678 (6%)
Frame = -2
Query: 2227 LDIQKEKNISEDLKETVKNLQSDLDIE----QKLSTDRQSEIYSLSAELERITQSEQMSL 2060
LD Q K++ E+LK V ++ + D + QK+ Q E SL + L++ +S + L
Sbjct: 1176 LDEQNTKSV-EELKTRVLEVEKERDEKHNNVQKIENKLQEESKSLES-LQKSQESNKSKL 1233
Query: 2059 KRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLS 1880
K L++ +LL+ +++ S K L+E+ + +K++ ++ +I L++ + N E+ L
Sbjct: 1234 KVLQDKLDSLLQEKNDLVSEKNNLKENFAKVKEDFEESQRKIHGLKESEKKKNHELHELQ 1293
Query: 1879 KFRYQVLELEEYSQQLSADLSKVHEDYSAALRQL-FDKKNEITCLQEVIEQKEVEERQRE 1703
K L+++ Q+ ADL + E+ L+ L D KN ++VIE+ E E+
Sbjct: 1294 KKFKGELDVK---QKQIADLERSREEVDKNLKNLQVDVKNVSEENKKVIEKLEKEKEALS 1350
Query: 1702 CMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNAC 1523
L +S+ N++ +KK+ EGK +L ++++QLT FKE+S K
Sbjct: 1351 LELNKLRKSSKENLDDRDKKIKDLEGKETKLSSELNQLT-------NKFKEDSKKNQENI 1403
Query: 1522 DLLQEIENFLREIRVE----TKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTL 1355
L+E + + + R E +K+ +++ + + + VK + S+L+ S+ D + +
Sbjct: 1404 QHLEEEKKIITDQRAELQKNSKMDLEKKEKKIRDLENSVKRISSELSKLQKSSQNDKEEV 1463
Query: 1354 SSTHQGSME-----DKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEY 1190
S + E +K + G + + Q + K+K++E
Sbjct: 1464 ESVKKDLQEKVQAFEKERKLLNEGSDAVTKQYSERITVLEDKVHQTELEVQRKNKELESA 1523
Query: 1189 KM----LQAELNNWLSCMNAEMGKFLCLC----NSMVYLEGDILKYKEDLLLNHGQLRAE 1034
K EL N L E+ ++ LE D+ +E L E
Sbjct: 1524 KSAADEASGELRNQLEEKVVEVSSLKSTIGEQEKAIKKLESDLTDSRESGNKKIEDLNGE 1583
Query: 1033 MSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMI----AEGQSKAFQLELKHANMS 866
+ +LK L +K + D+ E +D E SKA Q +L+++ S
Sbjct: 1584 LEALKKALSDKQAEIEANKSDLNKRAGERKELEDTIATLQKKVENSSKALQ-QLENSTDS 1642
Query: 865 ICS-----LSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFID 701
+ EK IE+ E V L KD D + QL + E SS KE L+
Sbjct: 1643 SKKNQENLIKEKDTNIEKLE-VAAKDLRKKDEDK---SKQLAALESEKSSMKENLE---K 1695
Query: 700 NMEASDTNLQSHFNQIQEM-LLNQNVNYPLEATVNIGFDQ-SMDEAVSEIA-----VQTF 542
N++ D ++ +Q+ +M L + ++ + F++ S E ++EI +Q
Sbjct: 1696 NVKEKDESIAQFKSQVADMESLKKELDENTNKLERMKFEEKSRIEKLTEITEEKKKIQKE 1755
Query: 541 PNKDTEDINTEIAHTSDKDEEVIKLQSQ----VENLQSLVQMLKQQNTKLEL----LAKK 386
K +ED K +E+ + +++ + L+ L+ ++ K E L+K
Sbjct: 1756 LEKRSEDAQNSRTELEQKTDELKRYEAEKKLTIGKLEKLLSEKERIIAKFEAEIADLSKS 1815
Query: 385 TSEMDPEKYFHFEELCQS 332
++ E H ++L S
Sbjct: 1816 NKDLKTELEQHSKKLSNS 1833
Score = 72.0 bits (175), Expect = 1e-09
Identities = 146/685 (21%), Positives = 281/685 (41%), Gaps = 58/685 (8%)
Frame = -2
Query: 2245 TLDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQM 2066
TL A ++ + EK ++L E V +L S + LS Q E L+ E+E+
Sbjct: 964 TLSAEKVKLNSEK---QELLEQVSSLNSSYE---SLSKRHQDETSDLNVEVEK------- 1010
Query: 2065 SLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKV 1886
LKE L E ++ + ++ E+ + L+++ QIE+ E E +A +
Sbjct: 1011 ----LKETVSHLKVQVDELKTSRDQITENANNLQEQCKIFEGQIENQEAEKKEAEKRYME 1066
Query: 1885 LSK-FRYQVLELEEYS---QQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVE 1718
L + F+ +LE+ + Q+L+ ++ + + L K+ ++ + E ++ E
Sbjct: 1067 LKQNFQVSTTDLEKLAKEKQELNDAKGSNEKELNKLKKDLEGKEQKLKSITERAQELEKT 1126
Query: 1717 ERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQL-----------TLSVD- 1574
++ A SER N+ ALE + + LEN++ QL T SV+
Sbjct: 1127 LDEQRNSNADSERKLKENIKALEHQKKEAISNSKELENELDQLKNKHKSLDEQNTKSVEE 1186
Query: 1573 ---FSAGVFKEESTKVSNACDLLQEIENFLRE---------------------IRVETKV 1466
V KE K +N +Q+IEN L+E ++ +
Sbjct: 1187 LKTRVLEVEKERDEKHNN----VQKIENKLQEESKSLESLQKSQESNKSKLKVLQDKLDS 1242
Query: 1465 TIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDP 1286
+QE V E +++ ++ +K E S H S + + E + G+ D
Sbjct: 1243 LLQEKNDLVSEKNNLKENFAKVKEDFEESQRKIHGLKESEKKKNHELHELQKKFKGELDV 1302
Query: 1285 KAXXXXXXXXXXXECRQNLENEECKSKQM-EEYKMLQAELNNWLSCMNAEMGKFLCLCNS 1109
K E +NL+N + K + EE K + +L ++ E+ K L S
Sbjct: 1303 KQKQIADLERSREEVDKNLKNLQVDVKNVSEENKKVIEKLEKEKEALSLELNK---LRKS 1359
Query: 1108 MVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDR 929
D K +DL +L +E++ L N F + + EN+Q + +++
Sbjct: 1360 SKENLDDRDKKIKDLEGKETKLSSELNQL------TNKFKEDSKKNQENIQH---LEEEK 1410
Query: 928 AMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLA 749
+I + +++ K++ M + +KI+ +E K + ++LS Q+
Sbjct: 1411 KIITDQRAEL----QKNSKMDLEKKEKKIRDLENSVKRISSELSKLQKSSQN-------D 1459
Query: 748 QEEISSTKEMLKDFIDNM--------EASDTNLQSHFNQI--------QEMLLNQNVNYP 617
+EE+ S K+ L++ + E SD + + +I Q L Q N
Sbjct: 1460 KEEVESVKKDLQEKVQAFEKERKLLNEGSDAVTKQYSERITVLEDKVHQTELEVQRKNKE 1519
Query: 616 LEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQV-ENLQS 440
LE+ + DEA E+ Q + ++++ + ++++ + KL+S + ++ +S
Sbjct: 1520 LESA-----KSAADEASGELRNQL--EEKVVEVSSLKSTIGEQEKAIKKLESDLTDSRES 1572
Query: 439 LVQMLKQQNTKLELLAKKTSEMDPE 365
+ ++ N +LE L K S+ E
Sbjct: 1573 GNKKIEDLNGELEALKKALSDKQAE 1597
Score = 65.5 bits (158), Expect = 1e-07
Identities = 133/664 (20%), Positives = 267/664 (40%), Gaps = 56/664 (8%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L+A++++I+K + E + +L S+ + K S + +S+ S + ++T+
Sbjct: 874 LEALQVNIKKAE-------ERIASLNSEKNALIKESGEWKSKFQSHDNLISKMTE----- 921
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVL 1883
+LK ++ E ++ER+SL L E+ S EL++ + ++ +L E + N E + L
Sbjct: 922 --KLKSFSESYKELQNERDSLSRSLHEASSNSSNELTALKNELATLSAEKVKLNSEKQEL 979
Query: 1882 SKFRYQVLELEEYSQQLSA--DLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQ 1709
LE+ S S+ LSK H+D ++ D E+ L+E + +V+ +
Sbjct: 980 ---------LEQVSSLNSSYESLSKRHQDETS------DLNVEVEKLKETVSHLKVQVDE 1024
Query: 1708 RECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQ-----LTLSVDFSAGV----- 1559
L S N N L+++ +EG+I E + + + L +F
Sbjct: 1025 ----LKTSRDQITENANNLQEQCKIFEGQIENQEAEKKEAEKRYMELKQNFQVSTTDLEK 1080
Query: 1558 -------------------------FKEESTKVSNACDLLQEIENFLREIRVETKVTIQE 1454
+ + K+ + + QE+E L E R + ++
Sbjct: 1081 LAKEKQELNDAKGSNEKELNKLKKDLEGKEQKLKSITERAQELEKTLDEQRNSNADSERK 1140
Query: 1453 ARHNVEEFSSVVKHLEYLKSQLETSNTMD-----HDTLSSTHQGSMED-KASSQSSTGDN 1292
+ N++ K E + + E N +D H +L + S+E+ K +
Sbjct: 1141 LKENIKALEHQKK--EAISNSKELENELDQLKNKHKSLDEQNTKSVEELKTRVLEVEKER 1198
Query: 1291 DPKAXXXXXXXXXXXECRQNLENE-ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLC 1115
D K Q +EN+ + +SK +E + Q + L + ++ L
Sbjct: 1199 DEKHNNV-----------QKIENKLQEESKSLESLQKSQESNKSKLKVLQDKLDSLLQEK 1247
Query: 1114 NSMV----YLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKEL 947
N +V L+ + K KED + + ++ LK +KN ++ +QK+
Sbjct: 1248 NDLVSEKNNLKENFAKVKEDF----EESQRKIHGLKESEKKKNH-------ELHELQKK- 1295
Query: 946 LIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLA 767
+K + + Q + + + ++ +L ++ + E K ++ +L + + + L+
Sbjct: 1296 --FKGELDVKQKQIADLERSREEVDKNLKNLQVDVKNVSEENKKVIEKL---EKEKEALS 1350
Query: 766 AQLTLAQEEISSTKEMLKD---FIDNMEASDTNLQSHFNQI-----QEMLLNQNVNYPLE 611
+L ++ S+KE L D I ++E +T L S NQ+ ++ NQ LE
Sbjct: 1351 LELNKLRK---SSKENLDDRDKKIKDLEGKETKLSSELNQLTNKFKEDSKKNQENIQHLE 1407
Query: 610 ATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQ 431
I DQ + + K D+ + S E+ KLQ +N + V+
Sbjct: 1408 EEKKIITDQRAELQKNSKMDLEKKEKKIRDLENSVKRIS---SELSKLQKSSQNDKEEVE 1464
Query: 430 MLKQ 419
+K+
Sbjct: 1465 SVKK 1468
Score = 59.7 bits (143), Expect = 5e-06
Identities = 111/583 (19%), Positives = 243/583 (41%), Gaps = 39/583 (6%)
Frame = -2
Query: 1993 ELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSK 1814
EL+E I L+ + +++ L LEK+L+ NEE + L+K ++VL+ + + S LSK
Sbjct: 700 ELKEGIKKLESDSNTSLLD---LEKKLHSLNEEHEKLNK-EHEVLQKDH--SEASEQLSK 753
Query: 1813 VHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSA 1634
+ ++ ++L D +T ++ + + ++++ A E +N N ++ E
Sbjct: 754 IRQE----CKELRDTLQAVTNERDNLSSENTKKQK------ALETANQTNTSSGE----- 798
Query: 1633 YEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQE 1454
K++ LEN + +T + + + + ++ + E+E+ +++++ +T E
Sbjct: 799 ---KVKTLENKLKGVTADKNKAEEGINKMTRELMSLTRSKGELESKIKDLQKKTDKLTNE 855
Query: 1453 ARHNVEEFSSVV----KHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDP 1286
+ F ++ ++LE L+ ++ + +L+S +++ +S +D
Sbjct: 856 FGKKEKVFEGILEKRDQNLEALQVNIKKAEER-IASLNSEKNALIKESGEWKSKFQSHDN 914
Query: 1285 KAXXXXXXXXXXXECRQNLENE-ECKSKQMEEYKMLQAE----LNNWLSCMNAEMGKFLC 1121
E + L+NE + S+ + E + L N L+ ++AE K
Sbjct: 915 LISKMTEKLKSFSESYKELQNERDSLSRSLHEASSNSSNELTALKNELATLSAEKVKLNS 974
Query: 1120 LCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLI 941
++ + E L H + E S L +E+ + + + + V+ ++
Sbjct: 975 EKQELLEQVSSLNSSYESLSKRH---QDETSDLNVEVEKLKETVSHLKVQVDELKTSRDQ 1031
Query: 940 WKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQ 761
+ A + Q K F+ ++++ +EK ++ E+R L TD++ LA +
Sbjct: 1032 ITENANNLQEQCKIFEGQIENQE------AEK-KEAEKRYMELKQNFQVSTTDLEKLAKE 1084
Query: 760 LTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEM------LLNQNVNYPLEATVN 599
+ S ++ L ++E + L+S + QE+ N N + + N
Sbjct: 1085 KQELNDAKGSNEKELNKLKKDLEGKEQKLKSITERAQELEKTLDEQRNSNADSERKLKEN 1144
Query: 598 I-GFDQSMDEAVS-----EIAVQTFPN----------KDTEDINTEIAHTSDKDEE---- 479
I + EA+S E + N K E++ T + + +E
Sbjct: 1145 IKALEHQKKEAISNSKELENELDQLKNKHKSLDEQNTKSVEELKTRVLEVEKERDEKHNN 1204
Query: 478 ----VIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEK 362
KLQ + ++L+SL + + +KL++L K + EK
Sbjct: 1205 VQKIENKLQEESKSLESLQKSQESNKSKLKVLQDKLDSLLQEK 1247
>ref|XP_005159741.1| PREDICTED: titin isoform X4 [Danio rerio]
Length = 15580
Score = 105 bits (261), Expect = 1e-19
Identities = 135/637 (21%), Positives = 287/637 (45%), Gaps = 30/637 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD + ++ K++ D+ ET+KN + LD +++ +++ EI + ++ S
Sbjct: 3781 LDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDED 3840
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEE---SISVLKQELSSARLQIESLEKELNQANEEV 1892
LK +K +Q E +++ E +K ELE I +K+E+ + R +E + +EL + E
Sbjct: 3841 LKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESF 3900
Query: 1891 KVL---SKFRYQVL-ELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKE 1724
L +K ++L E++ ++ L A+L K ++ + + ++ +E + +E
Sbjct: 3901 THLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLRE 3960
Query: 1723 VEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEES 1544
E Q + + +R + + +E + +A I ++ D+ +S+D A K +
Sbjct: 3961 DELGQLQAEIHKQQREIEKEKSNIESERAA----IIKIVEDLQHKIISLDRDAESLKLDR 4016
Query: 1543 TKVSNACDLLQ----EIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQLETS 1379
N ++L+ E+E EI + K+ Q R VEE ++ + K + + + +E +
Sbjct: 4017 EAFENEREVLKQMKTELERETDEIE-KIKLETQHDRQRVEEMTAQITKERDKINNLIEET 4075
Query: 1378 NTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE------- 1220
N D L+ ++ E S QS + + + +++LE +
Sbjct: 4076 NRKDM-VLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQKENTLAE 4134
Query: 1219 -----ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLN 1055
E K E + E+ + M + + L + L+ ++ K KE ++ +
Sbjct: 4135 IQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKD 4194
Query: 1054 HGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHA 875
R+E+ + EL ++ M + ++N +K L+ KD+ + E Q + + E +
Sbjct: 4195 ----RSELDLRQSELDKQQTNMNDIIETMKNERK--LLDKDKEEMEE-QKQEMEKERDNM 4247
Query: 874 NMSICSLSEKIQQIEEREKVL---LTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFI 704
+ SI SL E ++ ++ +++V+ +L ++Q A ++ +EE + ++ L+
Sbjct: 4248 DQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQNERQSLEKMT 4307
Query: 703 DNM--EASD-TNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNK 533
+ E D +L + + +EML V A + D ++ + E + +K
Sbjct: 4308 KALIKEREDLVHLAEYTKREKEMLDEMQV-----ANKSSMADLQREKRILEEMRENI-SK 4361
Query: 532 DTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
TEDI E + +++E+ KLQ++V+ QS + M K
Sbjct: 4362 QTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEK 4398
Score = 100 bits (250), Expect = 2e-18
Identities = 128/638 (20%), Positives = 274/638 (42%), Gaps = 31/638 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD + ++ K++ D+ ET+KN + LD +++ + +++ E+ + ++ +S
Sbjct: 5324 LDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 5383
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEE---SISVLKQELSSARLQIESLEKELNQANEEV 1892
LK +K +Q L + +S+ E +K ELE I +K+E+ + R +E + + L + E++
Sbjct: 5384 LKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL 5443
Query: 1891 KVLSKFRYQVL-ELEEYSQQLSAD-------LSKVHEDYSAALRQLFDKKNEITCLQEVI 1736
+K QVL E++ ++ AD L ++ E+ S + +KK + ++ +
Sbjct: 5444 AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDEL 5503
Query: 1735 EQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTL---SVDFSA 1565
Q + E +++ + + + + A+ K + + KI L+ D L L + +
Sbjct: 5504 RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEK 5563
Query: 1564 GVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQL 1388
V K+ T++ D +++I K+ Q R VEE ++ + K + + + +
Sbjct: 5564 EVLKQMKTELEREADEIEKI-----------KLETQHDRQRVEEMAAQIQKDRDEINNLI 5612
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE---- 1220
E +N D L+ ++ E S QS + + + +++LE +
Sbjct: 5613 EETNRKDM-VLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENT 5671
Query: 1219 --------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL 1064
E K E E+ + MN + + L + L+ ++ K KE +
Sbjct: 5672 LAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEII 5731
Query: 1063 LLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLEL 884
+ + QL S L + N M ++N +K+L KD+ + E Q + + E
Sbjct: 5732 MKDRSQLDLRQSELDKQQTNMNDIME----TMKNERKQL--DKDKEEMEE-QKQEMEKER 5784
Query: 883 KHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFI 704
+ + S SL E +++ K+ + ++ + +L +EIS KE ++
Sbjct: 5785 DNMDQSRKSLDED----QKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKR 5840
Query: 703 DNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAV----QTFPN 536
+E L + + + + + + + SM + E ++ + +
Sbjct: 5841 QRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENIS 5900
Query: 535 KDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
K E I+ E + +++E+ KLQ++V+ QS + M K
Sbjct: 5901 KLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEK 5938
Score = 97.8 bits (242), Expect = 2e-17
Identities = 125/659 (18%), Positives = 285/659 (43%), Gaps = 33/659 (5%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSL 2060
D + ++ K++ D+ ET+KN + LD +++ +++ E+ + ++ +S L
Sbjct: 6195 DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKDL 6254
Query: 2059 KRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQANE--- 1898
K +K +Q E +++ E +K ELE + I +K+E + R +E + +EL + E
Sbjct: 6255 KMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFT 6314
Query: 1897 --------EVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQE 1742
E ++L K + L Q+ ++L ++ E+ S + +KK + ++
Sbjct: 6315 HLAEDTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLRED 6374
Query: 1741 VIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTL---SVDF 1571
+ Q + E +++ + + + + A+ K + + KI L+ D L L + +
Sbjct: 6375 ELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFEN 6434
Query: 1570 SAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKS 1394
V K+ T++ D +++I K+ Q R VEE ++ ++ + +
Sbjct: 6435 EREVLKQMKTELEREADEIEKI-----------KLETQHERQRVEEMTADFMETMNNERK 6483
Query: 1393 QLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEEC 1214
QL+ + M E K + D D +Q LE E+
Sbjct: 6484 QLDKNKVMIE-----------EQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKN 6532
Query: 1213 KSKQM--------EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL-- 1064
K +QM +E ++ E N + L YL +I + + L
Sbjct: 6533 KLEQMKIGLEREADEISKIKEETQNERQNLEKMAN---ALKEEREYLAEEIKRKNQVLDK 6589
Query: 1063 --LLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKD--RAMIAEGQSKAF 896
+ N L A++ K L E + + D+EN +++ + +D + + E Q +
Sbjct: 6590 IKVANESTL-ADLQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQS 6648
Query: 895 QLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEML 716
+++++ N+ SE+ I E++ ++T+L K D++ ++ +E + + + +L
Sbjct: 6649 EIDMEKTNIE----SERAAMIREKQN-MMTELKKKSEDVEMQMKEILTEKELLHNDRNLL 6703
Query: 715 KDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPN 536
K +++++ +++ ++++ EA N ++M + +++ +Q
Sbjct: 6704 KKDVEDLQQKLMSIERD---------SESLKLDKEAFEN--EKEAMKQMKTDLQIQA--- 6749
Query: 535 KDTEDINTEIAHTSDK-DEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEK 362
+ E I E H + +E+ ++Q + E + +LV+ +K+ K +++ + +E+ EK
Sbjct: 6750 DEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIKK---KRDIIDESYTEIRKEK 6805
Score = 95.9 bits (237), Expect = 7e-17
Identities = 132/685 (19%), Positives = 288/685 (42%), Gaps = 26/685 (3%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
D+Q+EK+I E+++E + L+ +D E++ S R+ E+ L E++ K+ +
Sbjct: 5884 DLQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQ----------KQQSK 5933
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSK---- 1877
+ ESER ++ E + ++ LK++ +Q++ + E + + K+L++
Sbjct: 5934 IDMEKTNIESERAAMIREKQNMMTELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVEN 5993
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVE---ERQR 1706
+ ++++LE S++L D + E+ A++Q+ K ++ + IE+ ++E +RQR
Sbjct: 5994 LQQKLIDLERDSKRLKLD-REAFENEKEAMKQM---KTDLQIQADEIEKIKLETQHDRQR 6049
Query: 1705 ECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNA 1526
+AA + +N L ++ + + + D+ + S+ + ++E +
Sbjct: 6050 VEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKT 6109
Query: 1525 CDLLQEIENFLREIRVETKVTIQEARHNVEEFS-SVVKHLEYLKSQLETSNTMDHDTLSS 1349
L +++ L + + T IQ+ R +VE+ + ++ + + +K Q E N
Sbjct: 6110 RSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMN--------- 6160
Query: 1348 THQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-ECKSKQMEEYKMLQAE 1172
+D+ + N +Q LE E E K ++ + Q+E
Sbjct: 6161 ----QKQDELDQLKTEIQN----------------LQQELEKEKEIIMKDRSQFDLRQSE 6200
Query: 1171 L-------NNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIE 1013
L N+ + M E + M + ++ K K D + L ++ +K++
Sbjct: 6201 LDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKDLKMMKLQ 6260
Query: 1012 ---LVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSE-- 848
E+ + +++E E+ K+ + ELK S L+E
Sbjct: 6261 KQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFTHLAEDT 6320
Query: 847 -KIQQIEEREKV----LLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASD 683
K Q+I ++ KV L+ L + ++++ + ++ E++ + KE L+ D +
Sbjct: 6321 KKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLREDEL---- 6376
Query: 682 TNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIA 503
LQ+ + Q + + +N E I K+ ED+ +I
Sbjct: 6377 WQLQAEIYKQQREIEKEKINIESERAAII--------------------KNVEDLQHKII 6416
Query: 502 HTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEKYFHFEELCQSLVX 323
+ D+D E +KL E ++ ++LKQ T+LE A + ++ E H + + +
Sbjct: 6417 -SLDRDSESLKLDR--EAFENEREVLKQMKTELEREADEIEKIKLETQ-HERQRVEEMTA 6472
Query: 322 XXXXXXXXXXXXXXKNQVLVKQVKE 248
KN+V++++ K+
Sbjct: 6473 DFMETMNNERKQLDKNKVMIEEQKQ 6497
Score = 95.5 bits (236), Expect = 9e-17
Identities = 119/641 (18%), Positives = 277/641 (43%), Gaps = 34/641 (5%)
Frame = -2
Query: 2242 LDAVRLDIQKEKN----ISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQS 2075
++ ++L+ Q E+ ++ D ET+ N + L+ ++ +++ E+ ++++ +S
Sbjct: 4903 IEKIKLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKS 4962
Query: 2074 EQMSLKRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQA 1904
+LK +K +Q + E +++ E +K ELE + I +K+E + R ++E + +EL +
Sbjct: 4963 LDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEADEIRKIKEETQNERQRLEKMTEELKKE 5022
Query: 1903 NE-----------EVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI 1757
E E K+L K + L Q+ ++L ++ E+ S +K +I
Sbjct: 5023 KESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKI 5082
Query: 1756 TCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSV 1577
++ +EQ + E +++ + + +N+ A+ K + + K+ L+ D+ L L
Sbjct: 5083 RLREDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRDLESLKLDR 5142
Query: 1576 DFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYL 1400
+ F+ E + L+ + +I++ET Q R VEE ++ + K + +
Sbjct: 5143 E----AFENEREVLKQIKTDLKRKAEEIEKIKLET----QHDRQRVEEMTAQIQKERDKI 5194
Query: 1399 KSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE 1220
+ +E +N D L+ E + +S + + ++NLE +
Sbjct: 5195 NNLIEETNRKDM-VLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQ 5253
Query: 1219 ------------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKY 1076
E K E++ + ++ + M + + L + L+ ++ K
Sbjct: 5254 RKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQQELEKE 5313
Query: 1075 KEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAF 896
KE ++ + QL S L + N M ++N +K+L K+ E Q +
Sbjct: 5314 KEIIMKDRSQLDLRQSELDKQQTNVNDIME----TMKNERKQLDKDKEE---TEEQKQEM 5366
Query: 895 QLELKHANMSICSLSEKIQQIEEREKVL---LTQLSTKDTDMQHLAAQLTLAQEEISSTK 725
+ E + S SL E ++ ++ +++VL ++L +++ A ++ +EEI + +
Sbjct: 5367 EKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNER 5426
Query: 724 EMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQT 545
+ L+ + ++ +L + ++L V + +++E I
Sbjct: 5427 QNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENI---- 5482
Query: 544 FPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
+K TED+ + + +++E+ +LQ+++ Q ++ K
Sbjct: 5483 --SKQTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEK 5521
Score = 92.0 bits (227), Expect = 1e-15
Identities = 137/648 (21%), Positives = 278/648 (42%), Gaps = 30/648 (4%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIE-QKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++ +K+I E+ + + DL E K S D + ++ + E E + ++ K ++
Sbjct: 3594 EMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLTEKELLESDRKLLKKDVE 3653
Query: 2047 EAEQTLLEAESERESLKAE---LEESISVLKQELSSARLQIESLEKELNQANEEVKVLSK 1877
+Q LL ES+ ESLK + LE VLKQ + + + E +EK + E + + +
Sbjct: 3654 NLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEE 3713
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIE--QKEVEERQRE 1703
Q+ + EY Q+++ ++++ D +Q+ K++E+ L+ I+ Q+E+E+ +
Sbjct: 3714 MTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQELEKEKEI 3773
Query: 1702 CMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSV---------------DFS 1568
M SE D+ + L+K+ + I ++N+ QL DF
Sbjct: 3774 IMKDRSEL--DLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFD 3831
Query: 1567 AG--VFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKS 1394
G E+ + + +E +N L ++++E + E R EE + + LE +
Sbjct: 3832 QGRNSLDEDLKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTE 3891
Query: 1393 QLETSNTMDHDTLSSTHQGSMEDKASSQSSTGD----NDPKAXXXXXXXXXXXECRQNL- 1229
+L+ + S TH ED Q + N+ E R+N+
Sbjct: 3892 ELK------REKESFTHLA--EDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENIS 3943
Query: 1228 -ENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNH 1052
+ E+ K+K+ E ++ + EL + ++ + + +++ I+K EDL
Sbjct: 3944 KQTEDVKNKK-ENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKI 4002
Query: 1051 GQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHAN 872
L + SLK+ ++ F EN ++ L K + + +LE +H
Sbjct: 4003 ISLDRDAESLKL---DREAF--------ENEREVLKQMKTELERETDEIEKIKLETQHDR 4051
Query: 871 MSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNME 692
+ ++ +I + ++ L+ + + KD + + + I S K+ML+ N+E
Sbjct: 4052 QRVEEMTAQITKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLE 4111
Query: 691 ASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINT 512
+ +S +++E L Q N E Q E + K E+I
Sbjct: 4112 KT----RSELYKVKEDLEKQKENTLAEI-------QKEREDL---------EKMNENITI 4151
Query: 511 EIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTK-LELLAKKTSEMD 371
E+ ++E++ + Q +++ L++ +Q L+Q+ K E++ K SE+D
Sbjct: 4152 EMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELD 4199
Score = 84.0 bits (206), Expect = 3e-13
Identities = 137/676 (20%), Positives = 281/676 (41%), Gaps = 48/676 (7%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDL-DIEQKLSTDRQSEIYSLS-AELER---ITQ 2078
L R DI+K E K ++ + +L D + +L DR + ++ EL+R + +
Sbjct: 9048 LQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRE 9107
Query: 2077 SEQMSLKRLKEAEQTLL---EAESERESLK-------------AELEESISVLKQELSSA 1946
+E + K L++ EQ + + E++ E+L+ A+ E++ +Q+L
Sbjct: 9108 TEDLERKILQQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLL 9167
Query: 1945 RLQIESLEKELNQA--NEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFD 1772
+ ++S E EL EE K L + + + E + ++S ++ +Y + +L
Sbjct: 9168 QGALQSQESELENRVFMEEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQR 9227
Query: 1771 KKNEITCLQEVIEQKEVE--------ERQRECMLAASERSNDINVNALEKKLSA---YEG 1625
+K ++ + IEQ++ + ERQ E + D NALEK S +
Sbjct: 9228 EKEQLEISKNQIEQEKKDLQNMKSNLERQLESLRHEKANVED-EKNALEKMRSESKEIQN 9286
Query: 1624 KIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARH 1445
IR+ D+ + ++ +EE+ ++ + ++++++ L++ R + ++ +
Sbjct: 9287 AIRKEREDLENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINN 9346
Query: 1444 NVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXX 1265
+EE + + K ++E + D E + D K
Sbjct: 9347 KMEELLQMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQE--- 9403
Query: 1264 XXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDI 1085
+ E K + +E K L E+ + + EM + +G +
Sbjct: 9404 ------------KEREIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLL 9451
Query: 1084 LKYKEDLLLNHGQLRAEMSSL---KIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAE 914
K K++L +L +M L K E E+ + +E+++KE I K++ + +
Sbjct: 9452 EKEKQELKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEK 9511
Query: 913 GQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTK-DTDMQHLAAQLTLAQEE- 740
+ QL++ L+++ ++ ++EK L Q + + Q L T EE
Sbjct: 9512 SNIEEMQLKIFKQQR----LNDQTREENKKEKESLEQQRFETEQQKQMLEISTTKMMEEK 9567
Query: 739 -----ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMD 575
+S + KD ++ + A TN + H + + L+ + +E I D+
Sbjct: 9568 NEMADLSRELQKAKDELEKI-AYKTNKERHEVEQMQAELHSQIQ-AIEQQGQIMQDKQNH 9625
Query: 574 EAVSEIAVQTFPNK---DTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTK- 407
E+++Q + + E H ++ EE K Q +E +++ +++ KQ+N K
Sbjct: 9626 LEEKELSIQRKEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQKNNKD 9685
Query: 406 LELLAKKTSEMDPEKY 359
ELL K SE++ EKY
Sbjct: 9686 FELLEKIRSELENEKY 9701
Score = 80.1 bits (196), Expect = 4e-12
Identities = 118/630 (18%), Positives = 261/630 (41%), Gaps = 10/630 (1%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
D+Q+EK I E+++E + D++ E++ S R+ E+ L E++ K+ E
Sbjct: 4344 DLQREKRILEEMRENISKQTEDIENEKEKSKLREDELKKLQTEVQ----------KQQSE 4393
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESL--EKEL--NQANEEVKVLSK 1877
+ ESER + E + ++ LK++ +Q++ + EKEL N +N K +
Sbjct: 4394 IDMEKTNIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMED 4453
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVE---ERQR 1706
+ +++ +E S+ L D E + L K ++ + IE+ ++E +RQR
Sbjct: 4454 LKQKLMSIERDSESLKLD----REAFGNEKEVLKQMKTDLQIQADEIEKIKLETQHDRQR 4509
Query: 1705 ECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNA 1526
A + + +N L + + + + ++ D+ + S+ + ++E +
Sbjct: 4510 VEEKTAQIQKDRDEINNLIVETNRKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLEKT 4569
Query: 1525 -CDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSS 1349
+L + EN + +E K I++ + N+ +KH E Q + + +
Sbjct: 4570 RSELARAKENLETQREIERK-DIEKMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQN 4628
Query: 1348 THQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAEL 1169
Q ++K + D + + + ++NE KQ+++ K E
Sbjct: 4629 LQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNER---KQLDKDK---EET 4682
Query: 1168 NNWLSCMNAEMGKFLCLCNSMVYLEGDI--LKYKEDLLLNHGQLRAEMSSLKIELVEKNG 995
M E F S L+ D+ +K ++ ++ + ++++ +KIEL +
Sbjct: 4683 EEQKQEMEKEKHDF---DQSRKSLDEDLKMMKLQKQVI---EEEKSKLKQMKIELEREAD 4736
Query: 994 FMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKV 815
++ V++E ++ I E ++A + E + + ++ + +++ +
Sbjct: 4737 -------EIRKVKEET---QNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANES 4786
Query: 814 LLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLN 635
L + + +++Q + ++ E++ + KE ++ E LQ+ ++ Q
Sbjct: 4787 TLADILRERSNLQEMRENISKQTEDVENKKEKIR----LREEKLKQLQAEIHKQQSETEK 4842
Query: 634 QNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQV 455
+ N E I KD ED+ ++I + D+D E +KL
Sbjct: 4843 EKSNIERERAAII--------------------KDVEDLQSKII-SLDRDAESLKLDR-- 4879
Query: 454 ENLQSLVQMLKQQNTKLELLAKKTSEMDPE 365
E ++ + LKQ T+LE A + ++ E
Sbjct: 4880 EAFENEKEELKQMKTELEREADEIEKIKLE 4909
Score = 79.7 bits (195), Expect = 5e-12
Identities = 122/685 (17%), Positives = 295/685 (43%), Gaps = 64/685 (9%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
+I+KEK KE + + + +I + T+R+ E+Y + +ELER+ K+L +
Sbjct: 10841 EIKKEKE-----KENEEEEEEEEEIRVIVETERK-ELYQIKSELERVRSEIDHEQKKLND 10894
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSA--RLQIESLEKELNQANEEV--KVLSK 1877
+ + + + + E +K+E+ + +++E S ++Q +LEK + ++E+ K++ +
Sbjct: 10895 YMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVE 10954
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECM 1697
Q +++ ++L + K+ ++ + ++ +NE +++V E+ +++RE +
Sbjct: 10955 VEEQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKKVDEE---IKKERETL 11011
Query: 1696 LAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDL 1517
R +I++ +++L + + +R + D+ +++ ++ E+ + N DL
Sbjct: 11012 -----REMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDIN-------EQKLHLKNQRDL 11059
Query: 1516 LQEIENFLREIRVETKVTIQEARHNVEEFSSVV--KHLEYLKSQLETSNTMDHDTLSSTH 1343
L+ + R E + + + ++EF + V + + K ++E +T +
Sbjct: 11060 LE-------QEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARII 11112
Query: 1342 QGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECK---SKQMEEYKMLQAE 1172
+ M+ KA Q + + + + EE + + EE +++E
Sbjct: 11113 E--MKTKAELQEIMQEKEEE------------------DEEEMRVIVEMEREELNQIKSE 11152
Query: 1171 LNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSL---------- 1022
L S ++ E K + + D+ K K +++ Q+ E S L
Sbjct: 11153 LKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLE 11212
Query: 1021 KIELVEKNGFMGYAVLDVENVQKELLIWK-----DRAMIAEGQSKAFQ--LELKHANMSI 863
+ ++ + ++ VE +K++ + K +R IA+ Q Q +L++ N I
Sbjct: 11213 RHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERI 11272
Query: 862 CSLSEKI---------------QQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISST 728
+ E+I ++ EE V+ K D++ ++ + +++ +
Sbjct: 11273 KEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDVNKQNQDLMNQ 11332
Query: 727 KEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEA---VSEI 557
+++LK + + T LQ ++ + Q + +S++E + E+
Sbjct: 11333 RDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEM 11392
Query: 556 AVQTFP-----NKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLV-----------QML 425
+T P K+ E+ A K EE+ +++SQ+E ++S + +M+
Sbjct: 11393 KTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMI 11452
Query: 424 KQQNTKLEL----LAKKTSEMDPEK 362
+Q+ LE + K+ +M+ E+
Sbjct: 11453 EQEKEDLEKMKSEIMKQRQQMEEER 11477
Score = 78.6 bits (192), Expect = 1e-11
Identities = 129/680 (18%), Positives = 300/680 (44%), Gaps = 61/680 (8%)
Frame = -2
Query: 2227 LDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++IQKE+ I E LK + + DL+ E+ +++I SLS +L+ ++ E + R +
Sbjct: 3114 VEIQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI-SLSEDLKEQSEREGIDNTRTR 3172
Query: 2047 ----------------------EAEQTLLEAESER-ESLKAELEESISVLKQELSSARLQ 1937
E ++ ++E E ++ E +KAEL++ K EL + R
Sbjct: 3173 IKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNERQN 3232
Query: 1936 IESLEKELNQANEEVKVLSK--FRYQV----LELEEYSQQLSADLSKVHEDYSAALRQLF 1775
+E +L + E V+ L++ R QV +++E Q+ + + +K ++ L +L
Sbjct: 3233 LEEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQE--RVLIELK 3290
Query: 1774 DKKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVS 1595
+I +E +E + +EER++ + A ++ + L++ +S + I N
Sbjct: 3291 KTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDI---VNKTE 3347
Query: 1594 QLTLS----VDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFS 1427
QL L A +++++ +N ++ E + L + E +E +E S
Sbjct: 3348 QLRLREVELEQLQALIYRQQDEIEANRKAIINE-KYRLEGQKTEIDRLQREVNQMMEYAS 3406
Query: 1426 SVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSS-TGDNDPKAXXXXXXXXXX 1250
+LE KS++ + D + +G +E++ ++ + D K
Sbjct: 3407 KDRANLEKEKSEM-IAQKHQMDIELNKERGLIEERTQMLNTYEKEMDQKRTALEVEMKEL 3465
Query: 1249 XECRQNLENEECKSKQM--------EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLE 1094
+Q ++ E+ K +QM ++ K L+ + N + + + +L
Sbjct: 3466 KYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLAHLA 3525
Query: 1093 GDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAE 914
D + +++ + H A++ K L + M +++ +K++++ +D+ +
Sbjct: 3526 EDTKRKDDEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQQMQ 3585
Query: 913 GQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEIS 734
+ Q E+ SI + + + ++ + L+T+L+ + D++ ++ +E +
Sbjct: 3586 AEINRQQTEM-DTKKSI--IENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLTEKELLE 3642
Query: 733 STKEMLKDFIDNMEASDTNLQS---HFNQIQEMLLNQ---------NVNYPLEATVNIGF 590
S +++LK ++N++ ++S Q +E+L N+ ++ E I
Sbjct: 3643 SDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKL 3702
Query: 589 D-----QSMDEAVSEIAV-QTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQM 428
+ Q ++E ++I + + K ++I EI +++++ + Q +++ L++ +Q
Sbjct: 3703 ETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQN 3762
Query: 427 LKQQNTK-LELLAKKTSEMD 371
L+Q+ K E++ K SE+D
Sbjct: 3763 LQQELEKEKEIIMKDRSELD 3782
Score = 78.6 bits (192), Expect = 1e-11
Identities = 131/650 (20%), Positives = 261/650 (40%), Gaps = 30/650 (4%)
Frame = -2
Query: 2245 TLDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQM 2066
T+ R + K+K +E+ K+ ++ + D D +K S
Sbjct: 4667 TMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRK---------------------SLDE 4705
Query: 2065 SLKRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQANEE 1895
LK +K +Q + E +S+ + +K ELE + I +K+E + R E + + L + E+
Sbjct: 4706 DLKMMKLQKQVIEEEKSKLKQMKIELEREADEIRKVKEETQNERQIFEKMTEALKKERED 4765
Query: 1894 VKVLSKFRYQVL-ELEEYSQQLSAD-------LSKVHEDYSAALRQLFDKKNEITCLQEV 1739
+ +K + QVL E++ ++ AD L ++ E+ S + +KK +I +E
Sbjct: 4766 LSEDAKRKNQVLDEMKVANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLREEK 4825
Query: 1738 IEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGV 1559
++Q + E +++ + + + A+ K + + KI L+ D L L +
Sbjct: 4826 LKQLQAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDRE----A 4881
Query: 1558 FKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETS 1379
F+ E ++ L+ + + +I++ET Q R VEE ++ +ET
Sbjct: 4882 FENEKEELKQMKTELEREADEIEKIKLET----QHERQRVEEMTA---------DFMETM 4928
Query: 1378 NTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQM 1199
N + L+ + E K + D D +Q +E E+ K +QM
Sbjct: 4929 NN-ERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQM 4987
Query: 1198 --------EEYKMLQAELNN---WLSCMNAEMGKFLCLCNSMVYLEGDI---LKYKEDLL 1061
+E + ++ E N L M E+ K S +L D K + +
Sbjct: 4988 KIELEKEADEIRKIKEETQNERQRLEKMTEELKKEK---ESFTHLAEDTKTEKKILDKMK 5044
Query: 1060 LNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELK 881
+ + L A++ K L E + D E ++++ + +D + + Q E+K
Sbjct: 5045 VANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQLQAEIHKQQGEIK 5104
Query: 880 HANMSICSLSEKIQQIEEREKVLLTQLSTKDT-DMQHLAAQLTLAQEEISSTKEMLKDFI 704
EK ER ++ KD D+QH L E + +E ++
Sbjct: 5105 ---------MEKSNNESERAAII------KDVKDLQHKMFSLDRDLESLKLDREAFENER 5149
Query: 703 DNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTE 524
+ ++ T+L+ +I+++ L + Q ++E ++I K+ +
Sbjct: 5150 EVLKQIKTDLKRKAEEIEKIKLETQHD-----------RQRVEEMTAQI------QKERD 5192
Query: 523 DINTEIAHTSDKD----EEVIKLQSQVENLQSLVQMLKQQNTKLELLAKK 386
IN I T+ KD E +++ +++ ++S ML+++ LE K
Sbjct: 5193 KINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSK 5242
Score = 76.3 bits (186), Expect = 5e-11
Identities = 150/706 (21%), Positives = 304/706 (43%), Gaps = 71/706 (10%)
Frame = -2
Query: 2233 VRLDIQKEKNISEDLKET-------VKNLQSDLDIEQKLSTD--------------RQSE 2117
+++++QK+KN E+L+ T V+N + LD +QK D +SE
Sbjct: 13908 LQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSE 13967
Query: 2116 IYSLSAELERITQSEQMSLKRLKEAEQTLLE-----AESERESLKAE------LEESISV 1970
+ LS L Q EQ L+RL E E+ +E ESE++S++ E L+E + V
Sbjct: 13968 LNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIESEKQSIERERAELKRLKEEVEV 14027
Query: 1969 ------LKQELSSARLQIESLEKELNQANEEVKVL-SKFRYQVLELEEYSQQLSADLSKV 1811
L+Q+ + + + E LE E + EE+ L + + + EL+ ++++ A K
Sbjct: 14028 QHERTLLQQDKNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEA---KR 14084
Query: 1810 HEDYSAALRQLFD----KKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKK 1643
E+ L + + K E L+E I +K+ + ++ L + R + +L++
Sbjct: 14085 QEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQ-TSLDEI 14143
Query: 1642 LSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREI-RVET-- 1472
E + R LE V+ + V K E T S ++ + N ++E+ R++T
Sbjct: 14144 TKTDERRQRALEETVA----TTAKQPIVIKLEDTLTSEVQEMRDHLNNEIKELARMKTIM 14199
Query: 1471 ---KVTIQEARHNV----EEFSSVVKHLEYLKSQLE---TSNTMDHDTLSSTHQGSMEDK 1322
K +++A+ ++ EEF ++ KS+ E T D + LS+T +
Sbjct: 14200 KMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLD---KKN 14256
Query: 1321 ASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNA 1142
+++T K + ++N+ENE + KQ+E+ + +Q + + ++
Sbjct: 14257 KEIENNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQIEQEREIQRKAD--VTSTEK 14314
Query: 1141 EMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVE- 965
EM Y E + YK +L + +++ + S +EL + + + +
Sbjct: 14315 EM-----------YTEK--VTYKTELEDSKEKIKPDRDS-TLELTDTDSAKTDGEREAQT 14360
Query: 964 ---NVQKELLIWKDRAMIAEGQSKAFQ------LELKHANMSICSLSEKIQQIEEREKVL 812
VQ L + D E + LEL A + L E+ + EE + V+
Sbjct: 14361 LETKVQDVLQLTDDTTQDQEELHDEMENKMKIILELNKAKKDLQKLKEECRSAEEEKSVI 14420
Query: 811 LTQLSTKDTDMQHLAAQ-LTLAQE--EISSTKEMLKDFIDNMEASDTNLQSHFNQIQEML 641
+ L + ++ + ++ L+L QE ++ K ++ M+ ++ + + ++
Sbjct: 14421 MESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWE--TDVQ 14478
Query: 640 LNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKD-EEVIKLQ 464
+ Q P+E T +I +S +E ++ Q K + + +E+ D + E+V +++
Sbjct: 14479 IQQEGQEPIETTGHI-TKKSEEEISAKKTKQPIVTKLEDTLTSEVQEMRDMEIEDVARMK 14537
Query: 463 SQVENLQSLVQMLKQQ-NTKLELLAKKTSEMDPEKYFHFEELCQSL 329
+ ++ + ++ K ++E + E EK + E L Q L
Sbjct: 14538 TMMKMEKDQLEQAKSDIQRQMEEFERNMEETLKEKSRNEETLLQLL 14583
Score = 75.9 bits (185), Expect = 7e-11
Identities = 131/629 (20%), Positives = 268/629 (42%), Gaps = 25/629 (3%)
Frame = -2
Query: 2227 LDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++IQKE+ I E LK + + DL+ E+ +++I SL ELE ++ E + R++
Sbjct: 2720 VEIQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI-SLREELEEQSEKEGIDKTRVR 2778
Query: 2047 EAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRY 1868
+Q + E E R ++ ELE + + KQ + R +IE ++ EL +E K K R
Sbjct: 2779 -IKQEMDELEQTRLNVVKELENN-ELQKQIIEDERDKIEQIKAEL---QKEAKDTEKQRQ 2833
Query: 1867 QVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIE------QKE------ 1724
+ ++++ L +D + ++ D++ + L++ +E +KE
Sbjct: 2834 DIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDLKK 2893
Query: 1723 --VEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
E + E L + R ++I + ++K+ E +L+ +S+ ++ F++
Sbjct: 2894 TNTEMKDLEKQLESQNRQHEIQLAEIQKEREILE----QLKLTLSKQKEDLEKERDCFEK 2949
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFS-SVVKHLEYLKSQLETSNT 1373
E +S +L ++ E RE +T+V I++ +++ +VVK LE +N
Sbjct: 2950 EKADISLREELQEQSE---REGIGKTRVRIKKEMDELKQTRLNVVKELE--------NNE 2998
Query: 1372 MDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEE 1193
+ + + KA Q D + + E L+NE+ K +
Sbjct: 2999 LQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEK-KDIETST 3057
Query: 1192 YKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIE 1013
++ E N + E + +++ D+ K K ++ QL +++ +I+
Sbjct: 3058 DRIRDEEANLEVQKQRLESDR-----DTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQ 3112
Query: 1012 LVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELK--HANMSICSLSEKIQ 839
LVE +QKE I + + Q + + E + SLSE ++
Sbjct: 3113 LVE--------------IQKEREILEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLK 3158
Query: 838 QIEEREKV--LLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSH 665
+ ERE + T++ + +++ L QE K++++D D +E L+
Sbjct: 3159 EQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKE 3218
Query: 664 FNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEI---AHTS 494
+ + L N+ N EA + D+ E+++E + + I TE+ A+ S
Sbjct: 3219 AEKTKLELQNERQNLE-EAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANES 3277
Query: 493 DK---DEEVIKLQSQVENLQSLVQMLKQQ 416
+K + +I+L+ V ++ + L+ Q
Sbjct: 3278 NKQMQERVLIELKKTVTDIAGAKEDLENQ 3306
Score = 75.9 bits (185), Expect = 7e-11
Identities = 137/684 (20%), Positives = 276/684 (40%), Gaps = 75/684 (10%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L ++ ++ KEK E++K+ VK + ++ E++ + + + I +
Sbjct: 8971 LQQMKNELNKEKEQVEEMKQMVKTERVKIEQEKE----------EMRKQTQEIEDGHEKL 9020
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVL 1883
K+ + A++ L +A SE + LK +L + + +Q++ ++E+ ++ L++ + E+
Sbjct: 9021 QKKTEIADKLLQDANSESDRLK-DLSMKLQMQRQDIEKTNTEMETKKRSLDRMSREL--- 9076
Query: 1882 SKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRE 1703
Q L + Y + L K+ E+ E +E+K +++R+++
Sbjct: 9077 --------------QDDKIRLKNDRDAYEKDMTHLELKREELVRETEDLERKILQQREQD 9122
Query: 1702 CMLAASERSNDINVNALE-------KKLSAYEGKIRRLENDVSQLTL--------SVDFS 1568
M ++R + ALE KK + + ++ + ++ +L L +
Sbjct: 9123 EM---AKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQESELE 9179
Query: 1567 AGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQL 1388
VF EE + A +E L E+ E R +EE + LE K+Q+
Sbjct: 9180 NRVFMEEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQREKEQLEISKNQI 9239
Query: 1387 ETSNTMDHDTLSSTHQGSME----DKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLEN- 1223
E D + S + +E +KA+ + + + R++LEN
Sbjct: 9240 E-QEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENC 9298
Query: 1222 ---EECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNH 1052
E + K+MEE + +++E+ K ++ E I E+LL
Sbjct: 9299 WVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSR---ENIESREEKINNKMEELL--- 9352
Query: 1051 GQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDR------AMIAEGQ------ 908
Q++ EM K E+ +++ + A +D+EN + E+ +D+ I E +
Sbjct: 9353 -QMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQ 9411
Query: 907 --------SKAFQLELKHANMSICSLSEKIQQIE------EREKVLLTQLSTK-DTDMQH 773
S+ +L++K M + + + Q+IE E+EK L Q + + M
Sbjct: 9412 LDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMD 9471
Query: 772 LAAQLTLAQEE---ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLL----NQNVN--- 623
L + +EE + + K L+D E L + I+EM L Q +N
Sbjct: 9472 LTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQT 9531
Query: 622 -----YPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTE--DINTEIAHTSDKDEEVI--- 473
E+ F+ + + EI+ + E D++ E+ D+ E++
Sbjct: 9532 REENKKEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDELEKIAYKT 9591
Query: 472 -KLQSQVENLQ----SLVQMLKQQ 416
K + +VE +Q S +Q ++QQ
Sbjct: 9592 NKERHEVEQMQAELHSQIQAIEQQ 9615
Score = 75.1 bits (183), Expect = 1e-10
Identities = 131/671 (19%), Positives = 280/671 (41%), Gaps = 33/671 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD ++ ++Q E E++K + +++++ EQ+ + I +LE + +
Sbjct: 9942 LDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGDLEIMRADYE-- 9999
Query: 2062 LKRLKEAEQTLLEAESERESL---KAELEESISVLKQELSSARLQIESLEKELNQANEEV 1892
K+ ++ E+ +EA+ ER+ L K+ELE+ + + E +EKE N
Sbjct: 10000 -KQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKERNDLE--- 10055
Query: 1891 KVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQ--KEVE 1718
K+ S+ Q ++E+ +L + + + + K++I +E++E+ EVE
Sbjct: 10056 KMKSELMTQRQQMEDERSELDQKIKEANTE-----------KDKIEKNKEIVERLMAEVE 10104
Query: 1717 ERQRECML----AASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
E++ + L A ER N ++ L L+ E +++ + + E
Sbjct: 10105 EQRNDFKLKKEELALERQNIVDEKYL---LAQCETELQNKSEQIRNM------------E 10149
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTM 1370
E+ K N + L+E E L+ + E K I+E E+ + + K +L+
Sbjct: 10150 EAVK--NERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKK-- 10205
Query: 1369 DHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEY 1190
DTL + Q + D + R+ E + K+MEE
Sbjct: 10206 --DTLEQEREEINHKWTQFQQRIDEFDAQV-------------RKQKEEDLTNQKKMEEE 10250
Query: 1189 KMLQAELNNWLSCMNA----EMGKFLCLCNSMVYLEGDILKYKED---LLLNHGQLRAEM 1031
+ E+N + M E + + L+ I+K KE + + R ++
Sbjct: 10251 RKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAMTIKLKMEREDL 10310
Query: 1030 SSLKIELVEKNGFMGYAVLDVENVQKEL-----LIWKDRAMIAEGQSKAFQLELKHANMS 866
+K ELV + +V++ QK+L +I +++ + + +S+ + +
Sbjct: 10311 DQIKSELVREK-------TEVDHEQKKLNDDIKMIEQEKEDLEKMKSE-IMTQKQEMEKE 10362
Query: 865 ICSLSEKIQQIE------EREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFI 704
L KIQQ + E+ K ++ +L + + +H ++ L +EE+ ++ + D
Sbjct: 10363 RSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRH---EIQLQKEELDIERQKIADEQ 10419
Query: 703 DNMEASDTNLQSHFNQIQEMLLNQNVNYPLEA--TVNIGFDQSMDEAVSEIAVQTFPNKD 530
D + + + LQ+ +I+ +N+ + E + ++ +E S +D
Sbjct: 10420 DLLIQNKSELQNENERIRN--INEVIKKERETLKEMEAHLEKEKEEMKSITEETRRQKED 10477
Query: 529 TEDINTEIAHTSDKDEEVIK----LQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEK 362
E ++T+I +++++++K L+ + E++ L+Q+ + + K E D K
Sbjct: 10478 LEKMSTDI---KEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQVSKQKEEDLTK 10534
Query: 361 YFHFEELCQSL 329
+E +SL
Sbjct: 10535 QKEMKEERKSL 10545
Score = 75.1 bits (183), Expect = 1e-10
Identities = 132/702 (18%), Positives = 287/702 (40%), Gaps = 68/702 (9%)
Frame = -2
Query: 2245 TLDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLST-------DRQSEIYSLSAELER 2087
TL + ++KEK + + E + + DL +K+ST D +S+ L E E
Sbjct: 11841 TLKEMEAYLEKEKEEMKSITEETRRQKEDL---EKMSTHINEQKQDLRSQRDLLEQEREE 11897
Query: 2086 ITQSEQMSLKRL--------KEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIE 1931
I + +R+ K+ E+ L + + +E K+ E ++L+ + + + E
Sbjct: 11898 INHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMK---TKAEPE 11954
Query: 1930 SLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITC 1751
++KE + EE ++ K + E+E Q+ + L +V + ++L D K I
Sbjct: 11955 EIKKEKEKEEEEQEMRVKVEMERKEIE----QIKSQLERVRSEMDHEQKKLNDDKKMIEQ 12010
Query: 1750 LQEVIE--QKEVEERQRECMLAASERSNDINVNALEK-KLSAYEGKIRRLENDVSQLTLS 1580
+E +E + E+ +++++ SE I LEK + + + +L +V +
Sbjct: 12011 EKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHE 12070
Query: 1579 VDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYL 1400
+ F E K+++ DLL ++ K+ Q ++E +K
Sbjct: 12071 IQFQKEELDIERQKIADEQDLL-----------IQNKIEQQNENERIKEMDEEIKKERET 12119
Query: 1399 KSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE 1220
++E + + + + S + + K + + D + + +Q+L N+
Sbjct: 12120 LKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQ--------------KQDLMNQ 12165
Query: 1219 ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGD-----------ILKYK 1073
KQ E E+N+ L+ + + +F N +V + + +K
Sbjct: 12166 RDLLKQERE------EMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEY 12219
Query: 1072 EDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQ 893
E ++ + R E+ ++++ ++N + +E +K+ K+R E Q +A
Sbjct: 12220 ESIIEETNRKRTELEEIEVDQSQQNKNVETMKDLLEKERKD--TEKER---EELQKQADD 12274
Query: 892 LELK------HANMSICSLSEKIQQIEEREKVLLTQ---LSTKDTDMQHLAAQLTLAQEE 740
LE++ MS SL E+ + +E++ +L Q L + DM +L Q+E
Sbjct: 12275 LEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKE 12334
Query: 739 ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSE 560
I + K +++ +E + +++E L N V + +++ + + E
Sbjct: 12335 IQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKHQQQ-IEE 12393
Query: 559 IAVQTFPNKDTED----------------------INTEIAHTS---DKDEEVIKLQSQ- 458
+ V+T +D D + E+ T D EE +KL+ Q
Sbjct: 12394 MRVKTKMERDELDQLMAKMLMDRKENERSKDMIGLLKKEMEQTKFNLDAQEEELKLEKQK 12453
Query: 457 VENLQSLVQM----LKQQNTKLELLAKKTSEMDPEKYFHFEE 344
++N + ++M +K++ ++++ L ++ E D + + +E
Sbjct: 12454 IQNEKKDLEMFKAEIKREASEVKTLKEQQLEKDTKAFEALKE 12495
Score = 75.1 bits (183), Expect = 1e-10
Identities = 125/644 (19%), Positives = 282/644 (43%), Gaps = 28/644 (4%)
Frame = -2
Query: 2218 QKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELE-RITQSEQMSLKRLKEA 2042
+KEK+ +++ ++++S ++ +L T+ ++I +++EL+ R + E + K+ KE
Sbjct: 13358 RKEKHAEAEIQRQFEDIES---VKVRLVTE-SNQIDKMNSELKTRSEELENLIKKQQKEF 13413
Query: 2041 EQTLLEAESERESLK---AELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFR 1871
E E + ER++L+ AELE + LK ++ + L+KE N+ E +L + +
Sbjct: 13414 ETKENEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREK 13473
Query: 1870 YQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-----TCLQEV-IEQKEVEERQ 1709
++ + + QQ ++ + + + + L +NE+ + L + +E+ E+++ +
Sbjct: 13474 SELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLK 13533
Query: 1708 RECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSN 1529
E + + + S + L++ E K +L+N + ++ + + +E+ +
Sbjct: 13534 TE--IQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMD---KLSIQREKDSLEEI 13588
Query: 1528 ACDLLQEIENFLREIRVETKVT--IQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTL 1355
DL ++ E E+R ++T I + +++ + L +++ +E + L
Sbjct: 13589 KADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQAKI----L 13644
Query: 1354 SSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSK-QMEEYKMLQ 1178
S Q +K + S +ND R++LE + ++ ++E + +
Sbjct: 13645 ESDVQLLQTEKEILEKSKTEND--------------LLREDLEKQRKRNDLTLQELRKEK 13690
Query: 1177 AELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKN 998
L ++ + E L N V L+ LK KE L + R EM L+++L +
Sbjct: 13691 MALEQMITDITKEKDAVASLQNE-VSLKQHELKNKETEL---DEQRKEMDDLRMQLEMRQ 13746
Query: 997 GFMG-----YAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELK----HANMSICSLSEK 845
V VEN++ + + ++ E + + Q +K N+ S ++
Sbjct: 13747 NSTNKQQQEVDVFIVENMKMRNDLESMKTLLDE-ERRQLQDNIKTFEDQKNVLHPSKTDA 13805
Query: 844 IQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSH 665
+QQ +E EK T + T+ ++ ++ + +EI +KE L+ +E +
Sbjct: 13806 VQQTDELEK-FTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGK 13864
Query: 664 FNQIQEMLLNQNVNYPLEATVNIGFD--QSMDEAVSEIAVQTFPNKDTEDINTEIAHTSD 491
QI+ + L A + G D +++ + ++A++ K ++ + +
Sbjct: 13865 RAQIESL-------EQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKN 13917
Query: 490 KDEEVIKL----QSQVENLQSLVQMLKQQNTKLELLAKKTSEMD 371
+ EE+ + QVEN + + + KQQ +++ SE D
Sbjct: 13918 ELEELRNTIEAEKHQVENRK--IMLDKQQKEVEDIMTVIKSERD 13959
Score = 72.8 bits (177), Expect = 6e-10
Identities = 145/702 (20%), Positives = 296/702 (42%), Gaps = 82/702 (11%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSE--------- 2072
+IQKE+ I E LK T+ + DL+ E+ +++I SL EL+ ++ E
Sbjct: 2918 EIQKEREILEQLKLTLSKQKEDLEKERDCFEKEKADI-SLREELQEQSEREGIGKTRVRI 2976
Query: 2071 --------QMSLKRLKEAEQTLLE---AESER---ESLKAELE---ESISVLKQELSSAR 1943
Q L +KE E L+ E ER E +KAEL+ E ++++ R
Sbjct: 2977 KKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDR 3036
Query: 1942 LQIESLEKELNQANEEVKV-LSKFRYQVLELEEYSQQLSAD-----------------LS 1817
E + +L ++++ + R + LE Q+L +D +
Sbjct: 3037 RNNEEMVIKLQNEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKERFDLEKTKTEMG 3096
Query: 1816 KVHEDYSAALRQLFDKKNEITCLQEVIE--------QKEVEERQRECMLAASERSNDINV 1661
+ + + +RQ + EI +E++E QKE E++R+C + DI++
Sbjct: 3097 NLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCF---EKEKADISL 3153
Query: 1660 NALEKKLSAYEGKIRRLENDVSQLTLSVD----FSAGVFKEESTK------VSNACDLLQ 1511
+ K+ S EG ++N +++ +D + KE+ + + D ++
Sbjct: 3154 SEDLKEQSEREG----IDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIE 3209
Query: 1510 EIENFLREIRVETKVTIQEARHNVEEFSSVVK----HLEYLKSQLETSNTMDHDTLSSTH 1343
+I+ L++ +TK+ +Q R N+EE + +K ++E L +L + + T
Sbjct: 3210 QIKAELKKEAEKTKLELQNERQNLEEAGTKLKKDRENVESLAEELGRKQVVLENMQIET- 3268
Query: 1342 QGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNN 1163
M+ KA ++S+ + +++LEN+ + + E+ K+ QAE+
Sbjct: 3269 --EMQRKA-NESNKQMQERVLIELKKTVTDIAGAKEDLENQLLEER--EKNKVKQAEI-- 3321
Query: 1162 WLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQL----------RAEMSSLKIE 1013
AE L + + DI+ E L L +L + E+ + +
Sbjct: 3322 -----QAEKDMLYLLKQGISEQQVDIVNKTEQLRLREVELEQLQALIYRQQDEIEANRKA 3376
Query: 1012 LVEKNGFMGYAVLDVENVQKEL-----LIWKDRAMIAEGQSKAFQLELKHANMSICSLSE 848
++ + + +++ +Q+E+ KDRA + + +S+ + KH M I L++
Sbjct: 3377 IINEKYRLEGQKTEIDRLQREVNQMMEYASKDRANLEKEKSE--MIAQKH-QMDI-ELNK 3432
Query: 847 KIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQS 668
+ IEER ++ L+T + +M L + +E+ K+ +++ + ++ LQ
Sbjct: 3433 ERGLIEERTQM----LNTYEKEMDQKRTALEVEMKELKYHKQAIQEEKNKLQQMKIELQR 3488
Query: 667 HFNQIQEML-LNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSD 491
+ I+++ +N LE ++ D+ ++ +A T D + E A +D
Sbjct: 3489 EADDIKKLKEKTRNERQSLEKMAE-NLEKEKDD-LAHLAEDTKRKDDEMKVLHESA-LAD 3545
Query: 490 KDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPE 365
+E L+ E++ +M+ + K+ L K +M E
Sbjct: 3546 IQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQQMQAE 3587
Score = 70.9 bits (172), Expect = 2e-09
Identities = 105/631 (16%), Positives = 253/631 (40%), Gaps = 12/631 (1%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L+ V +IQ+EK + + + +L+ + +RQ +I + +LE E+
Sbjct: 9749 LNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLE-----EEKL 9803
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEES-ISVLKQELSSARLQIESLE---KELNQANEE 1895
L +++ + E +R+ K E+ E+ + V+K++ +AR + E + +E Q NE
Sbjct: 9804 LVQIEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNEN 9863
Query: 1894 VKVL-----SKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-TCLQEVIE 1733
K L Q EL++ + L + E+ + R L ++K + E++
Sbjct: 9864 AKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILR 9923
Query: 1732 QKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFK 1553
Q++ E+++E M+ KL + +++ + ++ +D
Sbjct: 9924 QRDDLEKEKEDMMKK------------WNKLDVLQNEMQNENKAMEEIKYELDGKRNEIN 9971
Query: 1552 EESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNT 1373
+E ++ + + E + L +R + + Q+ E K L+ +KS+LE T
Sbjct: 9972 KEQQRLEESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKT 10031
Query: 1372 -MDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQME 1196
+D++ + +M +K + ++ RQ +E+E
Sbjct: 10032 EIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQ------------RQQMEDE-------- 10071
Query: 1195 EYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKI 1016
++EL+ + N E K + L ++ + + D L +L E +
Sbjct: 10072 -----RSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQRNDFKLKKEELALERQN--- 10123
Query: 1015 ELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQ 836
+V++ + +++N +++ + + +K+ ++ +Q+
Sbjct: 10124 -IVDEKYLLAQCETELQNKSEQI--------------RNMEEAVKNERETLKETEAHLQR 10168
Query: 835 IEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQ 656
++ K ++ + S + D++ ++ + + ++E+ + K+ L+ + + T Q ++
Sbjct: 10169 DKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDE 10228
Query: 655 IQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDE-E 479
+ Q ++ + M+E K E++N +I K E E
Sbjct: 10229 FDAQVRKQKEE-------DLTNQKKMEE----------ERKCLEEVNGKIIEMKTKAELE 10271
Query: 478 VIKLQSQVENLQSLVQMLKQQNTKLELLAKK 386
++ ++E LQ+L + + ++ K E + K
Sbjct: 10272 HHEINQKIEELQTLQEQIMKEKEKAEAMTIK 10302
Score = 70.5 bits (171), Expect = 3e-09
Identities = 135/717 (18%), Positives = 295/717 (41%), Gaps = 94/717 (13%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKETVKNLQSD-------LDIEQKLSTDRQSEIYSLSAELERIT 2081
D R DI+ K I + L V+ + D LDIE++ D Q + A+L+
Sbjct: 11488 DLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNEN 11547
Query: 2080 QSEQMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQAN 1901
+ + + +K+ ++TL E E+ L+ E EE SV+++ + +E + ++N+ N
Sbjct: 11548 ERIKEMDEEIKKEKETLKEMEAH---LRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQN 11604
Query: 1900 EEV----KVLSKFRYQV----LELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQ 1745
+++ +L + R ++ +L++ + A +SK E+ +++ +++ + +
Sbjct: 11605 QDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETK 11664
Query: 1744 -EVIE----------QKEVEERQRECMLAASERSND-------------INVNALEKKLS 1637
++IE +KE E+ + E M A E + ++ +KKL+
Sbjct: 11665 IKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLN 11724
Query: 1636 AYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSN--------ACDLLQEIENFLREIR 1481
+ I + + D+ ++ + +EE +++ N CD IEN +EI
Sbjct: 11725 DDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCD----IEN-SKEIV 11779
Query: 1480 VETKVTIQEARHNVE--------EFSSVVKHLEYL---KSQLETSN----------TMDH 1364
+ V ++E +H ++ E + + L KS+L+ N +
Sbjct: 11780 QKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKER 11839
Query: 1363 DTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEE--- 1193
+TL ++K +S T + + E +Q+L ++ +Q E
Sbjct: 11840 ETLKEMEAYLEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEIN 11899
Query: 1192 --YKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLK 1019
+K LQ ++ + + ++ + + L M + + K ++L + +AE +K
Sbjct: 11900 HKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANIL--EMKTKAEPEEIK 11957
Query: 1018 IELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQ 839
E EK + VE +KE+ K + + Q +L I E ++
Sbjct: 11958 KE-KEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLE 12016
Query: 838 QIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFN 659
+++ Q+ + +++ Q L + +I ++KE+++ + +E +Q
Sbjct: 12017 KMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKE 12076
Query: 658 QI----------QEMLLNQNVNYPLEATVNIGFDQSMD---EAVSEIAVQTFPNKDTEDI 518
++ Q++L+ + E D+ + E + E+ V K+ E+I
Sbjct: 12077 ELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNL--QKEKEEI 12134
Query: 517 NTEIAHTSDKDEEVIKLQS----QVENLQSLVQMLKQQ----NTKLELLAKKTSEMD 371
+ I T + E++ K+ + Q ++L + +LKQ+ N KL L ++ E +
Sbjct: 12135 ESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFE 12191
Score = 67.4 bits (163), Expect = 3e-08
Identities = 132/650 (20%), Positives = 266/650 (40%), Gaps = 34/650 (5%)
Frame = -2
Query: 2224 DIQKEK-NISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
+I EK NI + ++ Q+ + +K S D + ++ + E E + + K ++
Sbjct: 6649 EIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVE 6708
Query: 2047 EAEQTLLEAESERESLKAE---LEESISVLKQELSSARLQIESLEK-ELNQANEEVKVLS 1880
+ +Q L+ E + ESLK + E +KQ + ++Q + +EK +L +E +V
Sbjct: 6709 DLQQKLMSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRV-- 6766
Query: 1879 KFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-TCLQEVIEQKEVEERQRE 1703
++ +A + K E+ + + ++ K++ I E+ ++KE E R
Sbjct: 6767 -------------EEKTAQIQKEREEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRS 6813
Query: 1702 CMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNAC 1523
+ A ++ N N +E L+ + K LE +S + S K E
Sbjct: 6814 DLEKAKSQTFKQNKN-IEIALAEIQQKRNALEK------MSKEISRDRMKLE-------- 6858
Query: 1522 DLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTH 1343
+ K IQ AR +E ++ + K L S D L +
Sbjct: 6859 ---------------DEKKEIQLAREELERMHGDMQRQQEAKDHL-LSGITDESLLKKSE 6902
Query: 1342 -----QGSMEDKA----SSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEEC-------- 1214
Q S DKA ++ S D P +++ E+E+
Sbjct: 6903 AEIVLQPSQVDKAKPARKTEISDSDKQPVFVQQMPEMDLKDALKKDFESEKLDLPKVKDV 6962
Query: 1213 --KSKQME-EYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQL 1043
+ +QM+ E K+++ E++ L M AE+ K E D ++ K+ + N Q
Sbjct: 6963 LPQDQQMKLEQKLIEDEMDK-LKQMRAELQK-----------EADQIEKKKQDMQNERQK 7010
Query: 1042 RAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLE---LKHAN 872
+M++ E N E + +E+ I K + + Q+ AFQ+E +
Sbjct: 7011 LDDMAARLQEERRTN----------ERLNEEINIQK---VNQQKQATAFQMEKTDFERIK 7057
Query: 871 MSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNME 692
I ++++ +E+ K +T++ + ++ + A ++ E I++ + L
Sbjct: 7058 TEIDQANKELADQQEKNKKTITEMQKERETLEEMRANISKQVETITNENKSL-------- 7109
Query: 691 ASDTNLQSHFNQIQEMLLNQNVNY-PLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDI- 518
++ +S ++QE +L Q L+ T+ + Q +D+ S+I + K+ +D+
Sbjct: 7110 ---SSRESELAKLQEDILQQQQEMDELKNTIMMEMCQ-LDQRQSDIDLL---QKEVDDLM 7162
Query: 517 ---NTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSE 377
TE+A+ + E +++ +Q N++S + LK + E L K +E
Sbjct: 7163 DFTKTEMANV---ERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNE 7209
Score = 67.0 bits (162), Expect = 3e-08
Identities = 116/631 (18%), Positives = 263/631 (41%), Gaps = 25/631 (3%)
Frame = -2
Query: 2188 KETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTLLEAESER 2009
+E + +++++DIE+ + + ELE+I Q +AE E
Sbjct: 12967 REELAKMKTEIDIERDEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQHDEIHGGI 13026
Query: 2008 ESLKAELEESISVLKQELSSARLQIESLEKELNQANEEV-KVLSKFRYQVLELE--EYSQ 1838
+SLK E EE I +K +L + + E++ + + +E+ K ++ +E E + +
Sbjct: 13027 DSLKEEREE-IEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDK 13085
Query: 1837 QLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVN 1658
L ++ K+ A L+ +KN + + E + +E E + C + E++ ++N
Sbjct: 13086 NLQDEMMKI----EAILKVTKKQKNYLEQMNENL-TREKTELETNCQMLEREKT-ELNKK 13139
Query: 1657 ALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRV 1478
E + + K+ E + + +D A EE K+ +E+ N EI+
Sbjct: 13140 VKETE-EFHMSKMEEREAERKTIERVMDEMA----EEHEKIKKE---REELVNMEEEIKK 13191
Query: 1477 ETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTG 1298
+ +V ++ E + L++ +S+L D ++S + ++ + S Q
Sbjct: 13192 QRRV----LEESMNEMTKKKSELQHERSELYKQKQQLEDMIASESKRDVDTERSRQDKED 13247
Query: 1297 DNDPKAXXXXXXXXXXXECRQNLENEECK---SKQMEEYKMLQAELNNWLSCMNAEMGKF 1127
+ K ++ + E K +++ E + +Q++LN+ M+ E K
Sbjct: 13248 EQILKREREEIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKL 13307
Query: 1126 LCL-------CNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDV 968
L + N++ + D+ K +E++ Q + E I + E +A ++
Sbjct: 13308 LYMKTEIQVKTNALEKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEI 13367
Query: 967 ENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKD 788
+ +++ K R + Q ELK + SE+++ + ++++ + TK+
Sbjct: 13368 QRQFEDIESVKVRLVTESNQIDKMNSELK-------TRSEELENLIKKQQ---KEFETKE 13417
Query: 787 TDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEM--LLNQNVNYPL 614
+MQ L E+ LK+ I+ + + +LQ N+ +E+ +L + +
Sbjct: 13418 NEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREKSELY 13477
Query: 613 EATVNIGFDQSMDEAVSEIA------VQTFPNKDTEDINTEIAHTSDKDEEVIKL----Q 464
+ + + E + + ++ N+ ++ + ++ S + E+ KL Q
Sbjct: 13478 QEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTEIQ 13537
Query: 463 SQVENLQSLVQMLKQQNTKLELLAKKTSEMD 371
S+ E+++ + LKQ + E K +++D
Sbjct: 13538 SEKESIEEEKKTLKQLKDENE---SKRTQLD 13565
Score = 65.9 bits (159), Expect = 7e-08
Identities = 135/678 (19%), Positives = 282/678 (41%), Gaps = 63/678 (9%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKE-------TVKNLQSDLDIEQKLSTDRQSEIYSLSAELERIT 2081
D + I KEK S ++E T + + +++ E++ RQ E+ E+ERI
Sbjct: 546 DVEKAKILKEKEESIRIREEARQERETTELVNAEIKAEKERLNQRQEEMLRERQEIERIK 605
Query: 2080 QSEQMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQAN 1901
+ + ++ ++ + + E +KAE++ I +++++ + E +E+ +
Sbjct: 606 HETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKEQMEEAKVELE 665
Query: 1900 EEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITC---------- 1751
EE + L + R V E ++ L ++ +V E+ + R+ ++ E+
Sbjct: 666 EEREDLERKRDLVSREIEQAEFLRNEILRVKEEMESRWRETETEEVELRAKTQHELERLE 725
Query: 1750 -LQEVIE--QKEVEERQRECML-------AASERSNDINVNALEKKLSAYEGKIRRLEND 1601
L+E E QK +EE + E ML E D +V ++ ++ + K +L
Sbjct: 726 KLREETERSQKNIEESKIELMLWKESLDKLKGEMEEDKHVVIMQ--MNEAKAKEEQLTMV 783
Query: 1600 VSQLTL---SVDFSAGVFKEESTKVSNACDLLQ----EIENFLREIRVETKVTIQEARHN 1442
+ QL + + S KEE +++ + LQ E+E++ R + E K A+
Sbjct: 784 IEQLEIERGEITISREKVKEELDEINRMRNELQRQHAEMEDWFRVVNKE-KEEANLAKLA 842
Query: 1441 VEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXX 1262
V E + LK Q+E S ++ ++ ++E + Q KA
Sbjct: 843 VHEAEML------LKKQMEESEKRRYEMITE----ALEQRDEIQK-------KAEELEQI 885
Query: 1261 XXXXXECRQNLE-----NEECKSKQME---EYKMLQAELNNWLSCMNAEMGKFLCLCNS- 1109
RQ LE +E K +E + ++ ++ + L A+ K L +S
Sbjct: 886 NKEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLFEMDSE 945
Query: 1108 ---MVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLI- 941
+ + + K+DL Q R EM VE++ + ++E ++ +L+I
Sbjct: 946 RKELEQMRFQVENEKKDL----EQRRYEMMRYD---VEQSAQVQRQKEELEKIKSQLVID 998
Query: 940 ----WKDRAMIAEGQSKAFQL--ELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDM 779
+ R + + + KA L E++ + E+ +Q EE ++L + + D+
Sbjct: 999 TESMNRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRLLRKDMENEREDL 1058
Query: 778 QHLAAQLTL--------AQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVN 623
+ + + TL +EEI+ + ++ D E D + N +E ++ +
Sbjct: 1059 EKIRVE-TLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRK--- 1114
Query: 622 YPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIK--LQSQVEN 449
+EA + M E + ++ V+ K+ D+ E A + E++K L Q E+
Sbjct: 1115 --MEA-----MKREMGE-IEDMKVELTKQKENIDMKMEHARLEMTNLEMMKADLLRQKED 1166
Query: 448 LQSLVQMLKQQNTKLELL 395
+++ + K + ++E++
Sbjct: 1167 IENQMLAAKSERQQMEVM 1184
Score = 65.5 bits (158), Expect = 1e-07
Identities = 142/774 (18%), Positives = 319/774 (41%), Gaps = 66/774 (8%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
+++ ++ + ED K ++N++ +L E + ++ +E + + + L++
Sbjct: 1805 NLEAQRKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEK 1864
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQ 1865
+ + ++ER +LE + + L+ + + + LEK +++ N + K +
Sbjct: 1865 KRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEK-ISELNSQQKDEIENEKS 1923
Query: 1864 VLELEEYS-QQLSADLSKVHEDYSAALRQLFDKKNEITCLQ-EVIEQ-KEVEERQRECML 1694
+++ EY QQ+ DL++ ++ +F +K+E+ Q E+ EQ K+V + +
Sbjct: 1924 KIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQDEIAEQLKQVGDMMQ---F 1980
Query: 1693 AASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLL 1514
+E+ N L+++ +A + ++E D++ L S + K+E V N LL
Sbjct: 1981 TQNEKDN------LDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKE---VLNEKRLL 2031
Query: 1513 QEIE-NFLREIR--VETKVTIQEARHNVE-EFSSVVKHLEYLKSQLET----SNTMDHDT 1358
++ + +R+++ + K+ ++ + ++ + S+ + + L+S L+T + + DT
Sbjct: 2032 EDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDT 2091
Query: 1357 LSSTHQGSMEDKA---------------SSQSSTGDNDPKAXXXXXXXXXXXECRQNLEN 1223
L+ + +ED A ++ D D + + +L+
Sbjct: 2092 LAEKQK--LEDAAVELQKERDEIMNIAEETKRKREDVDKIRVGIEKQEITFKDLKADLQK 2149
Query: 1222 E--------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKED 1067
E + K ++ K ++ ++ M+ + + ++ ++ ++ K +++
Sbjct: 2150 EAAIVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVDKERQE 2209
Query: 1066 LLLNHGQLRAEMSSLKIE------LVEKNGFMGYAV--------LDVENVQKELLIWKDR 929
+ +L E S L+ + EKN + + L EN+ KE I
Sbjct: 2210 VESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTI---- 2265
Query: 928 AMIAEGQSKAFQLELKHANMSICSLSEKIQQIEE------REKVLLTQLSTKDTDMQHLA 767
F+LE +H + K +QI+E EKV + Q+ D D Q
Sbjct: 2266 ----------FELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQA-DKDQQRKK 2314
Query: 766 AQL--------TLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLE 611
A+ T A EE E L++ +N+E + H N+ +E+ ++ + +E
Sbjct: 2315 AEYVKTARGRETTALEEQRQEMESLREEYENVEKQ----KKHVNEQKELFESRMKSLEME 2370
Query: 610 ATVNIGFDQSMDEAVSEIAVQ-TFPNKDTEDINTEIAHTSDKDEEVIK-LQSQVENLQSL 437
+ + +D+ ++ Q K+ + + TE+ ++ E K L+ Q + +
Sbjct: 2371 NEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTE 2430
Query: 436 VQMLKQQNTKLELLAKKTSEMDPEKYFHFEELCQSLVXXXXXXXXXXXXXXXKNQVLVKQ 257
ML+ Q +E KT E+D + +L S V + + VK+
Sbjct: 2431 TYMLETQKPVVE--KSKTDELDEVRKKINADL--SEVEKQKSALVQMNLKISQEESYVKK 2486
Query: 256 VKEMQVTLQSESPMEGETDSISENAIGSQPA--GKLSTELHNVHGNTERVPLQL 101
K+ ++E M+ + +N + + A K EL NV E+ +++
Sbjct: 2487 EKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEI 2540
Score = 65.5 bits (158), Expect = 1e-07
Identities = 135/673 (20%), Positives = 272/673 (40%), Gaps = 57/673 (8%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQ--------KLSTDR---QSEIYSLSAELERITQ 2078
D+QKEKN +E+LK ++ +S+L E+ ++ T R +SE+ +L +
Sbjct: 13454 DLQKEKNKTEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELED 13513
Query: 2077 SEQMSLKRLK----EAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELN 1910
++ L RL E ++ E +SE+ES++ E ++++ LK E S R Q+++ +++N
Sbjct: 13514 EKKSMLSRLSMEKHEIDKLKTEIQSEKESIEEE-KKTLKQLKDENESKRTQLDNTIEKMN 13572
Query: 1909 ----------QANEEVKVLSKFRYQVLELE-----EYSQQLSADLSKVHED--------- 1802
+ EE+K + + + L+ E + + Q+S D + +D
Sbjct: 13573 MDKLSIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRS 13632
Query: 1801 -YSAALRQLFDKKNEITCLQ---EVIEQKEVEERQRECMLAASERSNDINVNALEKKLSA 1634
+ RQ ++++ LQ E++E+ + E L + ND+ + L K+ A
Sbjct: 13633 MRADIERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEKQRKRNDLTLQELRKEKMA 13692
Query: 1633 YEGKIRRLEND---VSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVT 1463
E I + + V+ L V K + T++ + ++ L + T
Sbjct: 13693 LEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQ 13752
Query: 1462 IQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPK 1283
QE + E + LE +K+ L+ D + + S + D
Sbjct: 13753 QQEVDVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDEL 13812
Query: 1282 AXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMV 1103
+ E + +K++ + K LN + E+ S+
Sbjct: 13813 EKFTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLE 13872
Query: 1102 YLEGDILKYKED---LLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWK- 935
L D+L +D L+ Q+ E + K E VE + ++E ++ + K
Sbjct: 13873 QLRADLLAGADDIKTLVQTEKQMAIEDTEKKTE-VELQMNLQKQKNELEELRNTIEAEKH 13931
Query: 934 ---DRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAA 764
+R ++ + Q K + I ++ + + + E+EK L +LS L
Sbjct: 13932 QVENRKIMLDKQQKEVE--------DIMTVIKSERDVLEKEKSELNKLS------HVLNE 13977
Query: 763 QLTLAQEEISSTKEMLKDFIDN----MEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNI 596
++ QEE+ E +D I+N +E+ +++ +++ L + V E T+ +
Sbjct: 13978 KVQREQEELERLLEKERDDIENCKKIIESEKQSIERERAELKR--LKEEVEVQHERTL-L 14034
Query: 595 GFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQ 416
D++M + K+ E + E A T+ EE+ L+ +++ S + ML +
Sbjct: 14035 QQDKNMIQ------------KEKEHLEGEKARTT---EEIHNLKEEIKRKSSELDMLNK- 14078
Query: 415 NTKLELLAKKTSE 377
E+ AK+ E
Sbjct: 14079 ----EIEAKRQEE 14087
Score = 64.7 bits (156), Expect = 2e-07
Identities = 117/652 (17%), Positives = 266/652 (40%), Gaps = 26/652 (3%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L+ + D+QK K +E + L+ + QSE+ SL+ E++ + Q +
Sbjct: 14396 LNKAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIK--- 14452
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVL---KQELSSARLQIESLEKELNQANEEV 1892
E +Q ++ + + S+ + E + + ++ + + + E+E++ +
Sbjct: 14453 ----TEMQQIEIKMQIQTRSVATQWETDVQIQQEGQEPIETTGHITKKSEEEISAKKTKQ 14508
Query: 1891 KVLSKFRYQVL-ELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVE- 1718
+++K + E++E D++++ QL K++I E E+ E
Sbjct: 14509 PIVTKLEDTLTSEVQEMRDMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEET 14568
Query: 1717 ----ERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
R E +L +D++ N L++K E + +++QL ++ + K+
Sbjct: 14569 LKEKSRNEETLLQLLHDKDDLS-NTLDEKSKEIENITVTFKRNIAQLETTI----AMMKK 14623
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTM 1370
+ + N L++ E REI+ T T E E + V + L+ E
Sbjct: 14624 DKENIENELLQLKQTEQ-EREIQRGTDDTSNER----ENYDEKVTYKTELEDSKEKKKPD 14678
Query: 1369 DHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-ECKSKQMEE 1193
+L T S + ++ T + K + ++ L +E E K K + E
Sbjct: 14679 RDSSLKLTDADSAKTDGEREAQT--LETKVQDVLQLTDYTTQDQEELHDEMENKMKIILE 14736
Query: 1192 YKMLQAELNNWL-SCMNAEMGKFLCL------CNSMVYLEGDILKYKEDLLLNH-GQLRA 1037
+ +L C +AE K + + NS+ ++ ++L ++ ++H Q++
Sbjct: 14737 LNEAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQE--IDHLAQIKT 14794
Query: 1036 EMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICS 857
EM ++I++ + +V + W+ I +GQ E I
Sbjct: 14795 EMQQIEIKM----------QIQTRSVATQ---WETDVQIQQGQ------EATETTGHITK 14835
Query: 856 LSEKIQQIEEREKVLLTQL-STKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDT 680
SE+ ++ ++ +T+L T +++Q + L E+++ K ++K D +E + +
Sbjct: 14836 KSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVARMKTIMKMEKDQLEQAKS 14895
Query: 679 NLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAH 500
++Q+ + F+++M+EA+ E + ++++
Sbjct: 14896 DIQTQMEE---------------------FERNMEEAMEEKSRNEEKLLQLTHDKEDLSN 14934
Query: 499 TSDKDEEVIKLQSQ-----VENLQSLVQMLK--QQNTKLELLAKKTSEMDPE 365
T DK + I+ ++ + L++ + ++K ++N + ELL K +E + E
Sbjct: 14935 TLDKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQERE 14986
Score = 63.9 bits (154), Expect = 3e-07
Identities = 125/676 (18%), Positives = 275/676 (40%), Gaps = 49/676 (7%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDL-------KETVKNLQSDLDIEQKLSTDRQSEIYSL-SAELER 2087
++ + D+Q E+ +D+ + T + L +++I QK++ +Q+ + + + ER
Sbjct: 6997 IEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINI-QKVNQQKQATAFQMEKTDFER 7055
Query: 2086 ITQSEQMSLKRLKEAEQ----TLLEAESERESLKAELEESISVLKQELSSARLQIESLEK 1919
I + K L + ++ T+ E + ERE+L+ E+ +IS + +++ + S E
Sbjct: 7056 IKTEIDQANKELADQQEKNKKTITEMQKERETLE-EMRANISKQVETITNENKSLSSRES 7114
Query: 1918 ELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEV 1739
EL + E++ Q E++E + ++ QL ++++I LQ+
Sbjct: 7115 ELAKLQEDI------LQQQQEMDELKNTIMMEMC-----------QLDQRQSDIDLLQKE 7157
Query: 1738 I---------EQKEVEERQRECMLAASERSNDINVNALEK------KLSAYEGKIRRLEN 1604
+ E VE + E + +D+ +EK +L E K +E
Sbjct: 7158 VDDLMDFTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNEEK-DLIEK 7216
Query: 1603 DVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS 1424
+ LT ++D + + ++ N + I+N +E+ + K+++Q +EFS
Sbjct: 7217 ERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKELE-KMKISLQRKAIGFKEFSE 7275
Query: 1423 VVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXE 1244
K + ++ T D +G ++ Q+ + K E
Sbjct: 7276 KTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQT-----EKKRRKTYYTEDLFQE 7330
Query: 1243 CRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL 1064
+ +L+ K EE + E+ + +N E + S + +I K KE +
Sbjct: 7331 EKTDLQ------KTKEEINYDREEIYRQRTELNKEKETLKQMHTSNLKEIENIEKEKEKI 7384
Query: 1063 LLNHG---QLRAEMSSLKIELVEKNGFM----GYAVLDVENVQKELLIWKDRAMIAEGQS 905
Q+RAE+ + + ++ + M D+EN+Q E KD +
Sbjct: 7385 QRTWNELDQIRAELQNKQRDMDDTTNIMMKEKAELARDLENLQNE----KDELQKSRENI 7440
Query: 904 KAFQLELKHANMSIC-SLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISST 728
+ EL+ + +L+++ QQ E ++ K+ + + A++ + + +
Sbjct: 7441 QKLMKELQEERLKTSEALNKERQQFTE-------EIKLKNDSLDEIQAEIDRQKRALVTD 7493
Query: 727 KEML-KDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNI-----GFDQSMDEAV 566
KE++ K +D + D QS + I L + + +V I ++ DE +
Sbjct: 7494 KEIITKQMMDLQKTQDVRRQSDESDIARANLQRERESLDQLSVEILKQKQDLERERDELL 7553
Query: 565 SE---IAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQ-----VENLQSLVQMLKQQNT 410
+ + Q N++ + + TE+ + E++ K Q EN +L + L++ N
Sbjct: 7554 EQWRLVETQKMDNENVKQLKTELLDEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNL 7613
Query: 409 KLELLAKKTSEMDPEK 362
+ + + + ++++ K
Sbjct: 7614 QKQGIQDERAQLERMK 7629
Score = 63.9 bits (154), Expect = 3e-07
Identities = 130/706 (18%), Positives = 276/706 (39%), Gaps = 79/706 (11%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLD--------IEQKLSTDR------------- 2126
++ +R DI +EKN ++ +SDL+ +Q + +R
Sbjct: 12683 IEKIRQDIDREKN-------DLEKYRSDLEKQYEEMEICKQNIENERAELEIDLENIIIE 12735
Query: 2125 ----QSEIYSLSAELE---------------RITQSEQMSLKRLKEAEQTLLEAESERES 2003
Q + S+ +L+ R + + + K +E EQ E E++
Sbjct: 12736 TKSKQERLESIEVQLQEKNVQMGTILDELNKRQEELDAIKAKTQREKEQMGHTEELEKDE 12795
Query: 2002 LKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSAD 1823
L A L++ ++K+ + + Q E L+KE +Q L K + LE+E + L+++
Sbjct: 12796 LIAILQKREEIVKRHMEEIQNQREELQKEKDQFGNMQAELQKGQ---LEMEMHQLMLNSE 12852
Query: 1822 ----------LSKVHEDYSAALRQLFDKKNEITCLQEVI-EQKEVEERQRECMLAASERS 1676
L K E++ + L ++ E + L++++ E+K VEE M A +
Sbjct: 12853 RDELNGMRVNLEKQKEEFELMQQNLESRRPE-SLLEDILKEKKRVEE-----MAAQLSKE 12906
Query: 1675 NDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDL----LQE 1508
+ N + + + E KI+++E ++ + + + ++E + N + LQ
Sbjct: 12907 QEEFRNIMSETIKRME-KIKQIEGEIKTKQIEMACLEELKQKELDEQKNMRECENQELQM 12965
Query: 1507 IENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSN------TMDHDTLSST 1346
L +++ E + E + +++ LE +K L+ + HD +
Sbjct: 12966 RREELAKMKTEIDIERDEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQHDEIHGG 13025
Query: 1345 HQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELN 1166
E++ + D K + LE +E + +QM ++ E N
Sbjct: 13026 IDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQM----AVETEDN 13081
Query: 1165 NWLSCMNAEMGKFLCLC-------NSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELV 1007
+ + EM K + N + + ++ + K +L N L E + L ++
Sbjct: 13082 DSDKNLQDEMMKIEAILKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNKKVK 13141
Query: 1006 EKNGFMGYAVLDVENVQKELLIWKDRAM--IAEGQSKAFQLELKHANMSICSLSEKIQQI 833
E F + + E +K + +R M +AE K +K + ++ E+I++
Sbjct: 13142 ETEEFHMSKMEEREAERKTI----ERVMDEMAEEHEK-----IKKEREELVNMEEEIKKQ 13192
Query: 832 EEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQ-SHFNQ 656
+ + +++ K +++QH + E+ K+ L+D I + D + + S ++
Sbjct: 13193 RRVLEESMNEMTKKKSELQH-------ERSELYKQKQQLEDMIASESKRDVDTERSRQDK 13245
Query: 655 IQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEV 476
E +L + E ++++ Q K+ ED+ T + + E +
Sbjct: 13246 EDEQILKRE-----------------REEIADMKDQLL--KEKEDVETTKERINREKEHI 13286
Query: 475 IKLQSQVENL--------QSLVQMLKQQNTKLELLAKKTSEMDPEK 362
K+QSQ+ + Q L+ M + K L K ++ E+
Sbjct: 13287 EKMQSQLNDQKEEMDLENQKLLYMKTEIQVKTNALEKMMQDLQKER 13332
Score = 63.5 bits (153), Expect = 4e-07
Identities = 110/654 (16%), Positives = 277/654 (42%), Gaps = 44/654 (6%)
Frame = -2
Query: 2230 RLDIQKEKNISEDL-------KETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSE 2072
+ DI+ K I + L K ++ + +LDIE++ D Q + +EL+ +
Sbjct: 10655 KCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERI 10714
Query: 2071 QMSLKRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKEL-NQA 1904
+ + +K+ +TL E E+ E K E++ E LK++L + K+L NQ
Sbjct: 10715 RNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRLKEDLEKMSTDVNKQNKDLMNQR 10774
Query: 1903 N----EEVKVLSKFRYQVLELEEYSQQLS----ADLSKVHEDYSAALRQLFDKKNEITCL 1748
+ E ++ K++ ++E+ Q+S DL K + + L + K + +
Sbjct: 10775 DLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPK-EKGMKEDRKSLEETKANVIEM 10833
Query: 1747 QEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFS 1568
+ E +E+++ + + E +I V ++ Y+ +++++ ++ +D
Sbjct: 10834 KTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELYQ-----IKSELERVRSEID-- 10886
Query: 1567 AGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQL 1388
E K+++ ++++ + L +++ E Q+ E + ++ K +
Sbjct: 10887 -----HEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDI 10941
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKS 1208
E S + + E + Q + D + + + L+NE +
Sbjct: 10942 EKSKEIVEKLMVEVE----EQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERI 10997
Query: 1207 KQM-EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEM 1031
K++ EE K + L + E + + + D+ K D+ L+ +
Sbjct: 10998 KKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQR 11057
Query: 1030 SSLKIELVEKNGFMGYAVLDVE------NVQKELL----IWKDRAMIAEGQSKAFQLELK 881
L+ E E N M ++ + Q+E L + ++R + E +++ +++ K
Sbjct: 11058 DLLEQEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTK 11117
Query: 880 HANMSICSLSEKIQQIEEREKVLL----TQLSTKDTDMQHLAAQLTLAQEEISSTKEMLK 713
I + EK ++ EE +V++ +L+ ++++ + +++ Q++++ K++++
Sbjct: 11118 AELQEI--MQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIE 11175
Query: 712 DFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFD-QSMDEAVSEIAVQTFPN 536
+++E + + + Q++E ++ ++ T D ++ E V ++ V+
Sbjct: 11176 QEKEDLEKMKSEIMTQRQQMEEE--RSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQ 11233
Query: 535 K-----DTEDINTEIAHTSDKDEEVI----KLQSQVENLQSLVQMLKQQNTKLE 401
+ E+++ E +D+ V+ KLQ++ E ++ + + +K++ L+
Sbjct: 11234 RKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLK 11287
>ref|XP_005159740.1| PREDICTED: titin isoform X3 [Danio rerio]
Length = 15590
Score = 105 bits (261), Expect = 1e-19
Identities = 135/637 (21%), Positives = 287/637 (45%), Gaps = 30/637 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD + ++ K++ D+ ET+KN + LD +++ +++ EI + ++ S
Sbjct: 3781 LDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDED 3840
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEE---SISVLKQELSSARLQIESLEKELNQANEEV 1892
LK +K +Q E +++ E +K ELE I +K+E+ + R +E + +EL + E
Sbjct: 3841 LKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESF 3900
Query: 1891 KVL---SKFRYQVL-ELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKE 1724
L +K ++L E++ ++ L A+L K ++ + + ++ +E + +E
Sbjct: 3901 THLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLRE 3960
Query: 1723 VEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEES 1544
E Q + + +R + + +E + +A I ++ D+ +S+D A K +
Sbjct: 3961 DELGQLQAEIHKQQREIEKEKSNIESERAA----IIKIVEDLQHKIISLDRDAESLKLDR 4016
Query: 1543 TKVSNACDLLQ----EIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQLETS 1379
N ++L+ E+E EI + K+ Q R VEE ++ + K + + + +E +
Sbjct: 4017 EAFENEREVLKQMKTELERETDEIE-KIKLETQHDRQRVEEMTAQITKERDKINNLIEET 4075
Query: 1378 NTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE------- 1220
N D L+ ++ E S QS + + + +++LE +
Sbjct: 4076 NRKDM-VLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQKENTLAE 4134
Query: 1219 -----ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLN 1055
E K E + E+ + M + + L + L+ ++ K KE ++ +
Sbjct: 4135 IQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKD 4194
Query: 1054 HGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHA 875
R+E+ + EL ++ M + ++N +K L+ KD+ + E Q + + E +
Sbjct: 4195 ----RSELDLRQSELDKQQTNMNDIIETMKNERK--LLDKDKEEMEE-QKQEMEKERDNM 4247
Query: 874 NMSICSLSEKIQQIEEREKVL---LTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFI 704
+ SI SL E ++ ++ +++V+ +L ++Q A ++ +EE + ++ L+
Sbjct: 4248 DQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQNERQSLEKMT 4307
Query: 703 DNM--EASD-TNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNK 533
+ E D +L + + +EML V A + D ++ + E + +K
Sbjct: 4308 KALIKEREDLVHLAEYTKREKEMLDEMQV-----ANKSSMADLQREKRILEEMRENI-SK 4361
Query: 532 DTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
TEDI E + +++E+ KLQ++V+ QS + M K
Sbjct: 4362 QTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEK 4398
Score = 102 bits (253), Expect = 9e-19
Identities = 127/657 (19%), Positives = 292/657 (44%), Gaps = 30/657 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD + ++ K++ D+ ET+KN + LD +++ +++ E+ +++ +S
Sbjct: 6204 LDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDED 6263
Query: 2062 LKRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQANEEV 1892
LK +K +Q + E +++ E +K ELE + I +K+E + R +E + +EL + ++V
Sbjct: 6264 LKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDV 6323
Query: 1891 KVLS----KFRYQVLELEEYSQQLSADLSK-------VHEDYSAALRQLFDKKNEITCLQ 1745
L+ + + + E++ ++ ADL K + E+ S + +K++I +
Sbjct: 6324 AHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLRE 6383
Query: 1744 EVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSA 1565
+ +EQ + E +++ + + + A+ K + + KI L+ D L L +
Sbjct: 6384 DELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDRE--- 6440
Query: 1564 GVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQL 1388
F+ E ++ L+ + + +I++ET Q R VEE ++ ++ + + QL
Sbjct: 6441 -AFENEKEELKQMKTELEREADEIEKIKLET----QHERQRVEEMTADFMETMNNERKQL 6495
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKS 1208
+ + M E K + D D +Q LE E+ K
Sbjct: 6496 DKNKVMIE-----------EQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKL 6544
Query: 1207 KQM--------EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL---- 1064
+QM +E ++ E N + L YL +I + + L
Sbjct: 6545 EQMKIGLEREADEISKIKEETQNERQNLEKMAN---ALKEEREYLAEEIKRKNQVLDKIK 6601
Query: 1063 LLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKD--RAMIAEGQSKAFQL 890
+ N L A++ K L E + + D+EN +++ + +D + + E Q + ++
Sbjct: 6602 VANESTL-ADLQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEI 6660
Query: 889 ELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKD 710
+++ N+ SE+ I E++ ++T+L K D++ ++ +E + + + +LK
Sbjct: 6661 DMEKTNIE----SERAAMIREKQN-MMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKK 6715
Query: 709 FIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKD 530
+++++ +++ ++++ EA N ++M + +++ +Q +
Sbjct: 6716 DVEDLQQKLMSIERD---------SESLKLDKEAFEN--EKEAMKQMKTDLQIQA---DE 6761
Query: 529 TEDINTEIAHTSDK-DEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEK 362
E I E H + +E+ ++Q + E + +LV+ +K+ K +++ + +E+ EK
Sbjct: 6762 IEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIKK---KRDIIDESYTEIRKEK 6815
Score = 100 bits (250), Expect = 2e-18
Identities = 128/638 (20%), Positives = 274/638 (42%), Gaps = 31/638 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD + ++ K++ D+ ET+KN + LD +++ + +++ E+ + ++ +S
Sbjct: 4917 LDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 4976
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEE---SISVLKQELSSARLQIESLEKELNQANEEV 1892
LK +K +Q L + +S+ E +K ELE I +K+E+ + R +E + + L + E++
Sbjct: 4977 LKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL 5036
Query: 1891 KVLSKFRYQVL-ELEEYSQQLSAD-------LSKVHEDYSAALRQLFDKKNEITCLQEVI 1736
+K QVL E++ ++ AD L ++ E+ S + +KK + ++ +
Sbjct: 5037 AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDEL 5096
Query: 1735 EQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTL---SVDFSA 1565
Q + E +++ + + + + A+ K + + KI L+ D L L + +
Sbjct: 5097 RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEK 5156
Query: 1564 GVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQL 1388
V K+ T++ D +++I K+ Q R VEE ++ + K + + + +
Sbjct: 5157 EVLKQMKTELEREADEIEKI-----------KLETQHDRQRVEEMAAQIQKDRDEINNLI 5205
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE---- 1220
E +N D L+ ++ E S QS + + + +++LE +
Sbjct: 5206 EETNRKDM-VLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENT 5264
Query: 1219 --------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL 1064
E K E E+ + MN + + L + L+ ++ K KE +
Sbjct: 5265 LAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEII 5324
Query: 1063 LLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLEL 884
+ + QL S L + N M ++N +K+L KD+ + E Q + + E
Sbjct: 5325 MKDRSQLDLRQSELDKQQTNMNDIME----TMKNERKQL--DKDKEEMEE-QKQEMEKER 5377
Query: 883 KHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFI 704
+ + S SL E +++ K+ + ++ + +L +EIS KE ++
Sbjct: 5378 DNMDQSRKSLDED----QKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKR 5433
Query: 703 DNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAV----QTFPN 536
+E L + + + + + + + SM + E ++ + +
Sbjct: 5434 QRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENIS 5493
Query: 535 KDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
K E I+ E + +++E+ KLQ++V+ QS + M K
Sbjct: 5494 KLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEK 5531
Score = 96.7 bits (239), Expect = 4e-17
Identities = 120/630 (19%), Positives = 272/630 (43%), Gaps = 12/630 (1%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
D+Q+EK I E+++E + D++ E++ S R+ E+ L E++ K+ E
Sbjct: 4344 DLQREKRILEEMRENISKQTEDIENEKEKSKLREDELKKLQTEVQ----------KQQSE 4393
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESL--EKEL--NQANEEVKVLSK 1877
+ ESER + E + ++ LK++ +Q++ + EKEL N +N K +
Sbjct: 4394 IDMEKTNIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMED 4453
Query: 1876 FRYQVLELEEYSQQLSADL------SKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEE 1715
+ +++ +E S+ L D +V + L+ D+ +I L+ E++ VEE
Sbjct: 4454 LKQKLMSIERDSESLKLDREAFGNEKEVLKQMKTDLQIQADEIEKIK-LETQHERQRVEE 4512
Query: 1714 RQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKV 1535
+ M + +N N ++++ + ++ + +D+ Q S+D + + K +
Sbjct: 4513 MTADFMETMNNERKQLNKN--KEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQK--- 4567
Query: 1534 SNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTL 1355
+++E +N L ++++E + E R EE + + LE + +L+ + ++
Sbjct: 4568 ----QVIEEEKNKLEQMKIELEKEADEIRKIKEETQNERQRLEKMTEELK----KEKESF 4619
Query: 1354 SSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-ECKSKQMEEYKMLQ 1178
+ + + +K N+ E R+N+ + E K+ E+ ++ +
Sbjct: 4620 THLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLRE 4679
Query: 1177 AELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKN 998
EL + ++ + G+ ++ I+K +DL L ++ SLK+ ++
Sbjct: 4680 DELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRDLESLKL---DRE 4736
Query: 997 GFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREK 818
F EN ++ L K + + +LE +H + ++ +IQ+ ++
Sbjct: 4737 AF--------ENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVEEMTAQIQKERDKIN 4788
Query: 817 VLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLL 638
L+ + + KD + + ++ + I S ++ML+ ++E + + LL
Sbjct: 4789 NLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLE-----------KTRSKLL 4837
Query: 637 NQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQ 458
N + + + Q E + K E EI ++E++ + Q +
Sbjct: 4838 RAKENLEKQRKIKLAEIQKEREDL---------EKMNEKFTIEIHDIKHQEEQMKQKQDE 4888
Query: 457 VENLQSLVQMLKQQNTK-LELLAKKTSEMD 371
++ L++ +Q L+Q+ K E++ K S++D
Sbjct: 4889 LDQLKTEIQNLQQELEKEKEIIMKDRSQLD 4918
Score = 95.1 bits (235), Expect = 1e-16
Identities = 127/646 (19%), Positives = 274/646 (42%), Gaps = 26/646 (4%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
D+Q+EK+I E+++E + L+ +D E++ S R+ E+ L E++ K+ +
Sbjct: 5477 DLQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQ----------KQQSK 5526
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSK---- 1877
+ ESER ++ E + ++ LK++ +Q++ + E + + K+L++
Sbjct: 5527 IDMEKTNIESERAAMIREKQNMMTELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVEN 5586
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVE---ERQR 1706
+ ++++LE S++L D + E+ A++Q+ K ++ + IE+ ++E +RQR
Sbjct: 5587 LQQKLIDLERDSKRLKLD-REAFENEKEAMKQM---KTDLQIQADEIEKIKLETQHDRQR 5642
Query: 1705 ECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNA 1526
+AA + +N L ++ + + + D+ + S+ + ++E +
Sbjct: 5643 VEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKT 5702
Query: 1525 CDLLQEIENFLREIRVETKVTIQEARHNVEEFS-SVVKHLEYLKSQLETSNTMDHDTLSS 1349
L +++ L + + T IQ+ R +VE+ + ++ + + +K Q E N
Sbjct: 5703 RSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMN--------- 5753
Query: 1348 THQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-ECKSKQMEEYKMLQAE 1172
+D+ + N +Q LE E E K ++ + Q+E
Sbjct: 5754 ----QKQDELDQLKTEIQN----------------LQQELEKEKEIIMKDRSQFDLRQSE 5793
Query: 1171 L-------NNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIE 1013
L N+ + M E + M + ++ K K D + L ++ +K++
Sbjct: 5794 LDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKDLKMMKLQ 5853
Query: 1012 ---LVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSE-- 848
E+ + +++E E+ K+ + ELK S L+E
Sbjct: 5854 KQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFTHLAEDT 5913
Query: 847 -KIQQIEEREKV----LLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASD 683
K Q+I ++ KV L+ L + ++++ + ++ E++ + KE L+ D +
Sbjct: 5914 KKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLREDEL---- 5969
Query: 682 TNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIA 503
LQ+ + Q + + +N E I K+ ED+ +I
Sbjct: 5970 WQLQAEIYKQQREIEKEKINIESERAAII--------------------KNVEDLQHKII 6009
Query: 502 HTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPE 365
+ D+D E +KL E ++ ++LKQ T+LE A + ++ E
Sbjct: 6010 -SLDRDSESLKLDR--EAFENEREVLKQMKTELEREADEIEKIKLE 6052
Score = 92.0 bits (227), Expect = 1e-15
Identities = 137/648 (21%), Positives = 278/648 (42%), Gaps = 30/648 (4%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIE-QKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++ +K+I E+ + + DL E K S D + ++ + E E + ++ K ++
Sbjct: 3594 EMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLTEKELLESDRKLLKKDVE 3653
Query: 2047 EAEQTLLEAESERESLKAE---LEESISVLKQELSSARLQIESLEKELNQANEEVKVLSK 1877
+Q LL ES+ ESLK + LE VLKQ + + + E +EK + E + + +
Sbjct: 3654 NLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEE 3713
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIE--QKEVEERQRE 1703
Q+ + EY Q+++ ++++ D +Q+ K++E+ L+ I+ Q+E+E+ +
Sbjct: 3714 MTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQELEKEKEI 3773
Query: 1702 CMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSV---------------DFS 1568
M SE D+ + L+K+ + I ++N+ QL DF
Sbjct: 3774 IMKDRSEL--DLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFD 3831
Query: 1567 AG--VFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKS 1394
G E+ + + +E +N L ++++E + E R EE + + LE +
Sbjct: 3832 QGRNSLDEDLKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTE 3891
Query: 1393 QLETSNTMDHDTLSSTHQGSMEDKASSQSSTGD----NDPKAXXXXXXXXXXXECRQNL- 1229
+L+ + S TH ED Q + N+ E R+N+
Sbjct: 3892 ELK------REKESFTHLA--EDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENIS 3943
Query: 1228 -ENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNH 1052
+ E+ K+K+ E ++ + EL + ++ + + +++ I+K EDL
Sbjct: 3944 KQTEDVKNKK-ENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKI 4002
Query: 1051 GQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHAN 872
L + SLK+ ++ F EN ++ L K + + +LE +H
Sbjct: 4003 ISLDRDAESLKL---DREAF--------ENEREVLKQMKTELERETDEIEKIKLETQHDR 4051
Query: 871 MSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNME 692
+ ++ +I + ++ L+ + + KD + + + I S K+ML+ N+E
Sbjct: 4052 QRVEEMTAQITKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLE 4111
Query: 691 ASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINT 512
+ +S +++E L Q N E Q E + K E+I
Sbjct: 4112 KT----RSELYKVKEDLEKQKENTLAEI-------QKEREDL---------EKMNENITI 4151
Query: 511 EIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTK-LELLAKKTSEMD 371
E+ ++E++ + Q +++ L++ +Q L+Q+ K E++ K SE+D
Sbjct: 4152 EMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELD 4199
Score = 92.0 bits (227), Expect = 1e-15
Identities = 127/649 (19%), Positives = 278/649 (42%), Gaps = 43/649 (6%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSL 2060
D + ++ K++ D+ ET+KN + LD +++ +++ E+ + ++ +S L
Sbjct: 5788 DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKDL 5847
Query: 2059 KRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQANE--- 1898
K +K +Q E +++ E +K ELE + I +K+E + R +E + +EL + E
Sbjct: 5848 KMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFT 5907
Query: 1897 --------EVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQE 1742
E ++L K + L Q+ ++L ++ E+ S + +KK + ++
Sbjct: 5908 HLAEDTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLRED 5967
Query: 1741 VIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTL---SVDF 1571
+ Q + E +++ + + + + A+ K + + KI L+ D L L + +
Sbjct: 5968 ELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFEN 6027
Query: 1570 SAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKS 1394
V K+ T++ D +++I K+ Q R VEE ++ + K + + +
Sbjct: 6028 EREVLKQMKTELEREADEIEKI-----------KLETQHDRQRVEEMTAQIQKDRDKINN 6076
Query: 1393 QLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-- 1220
+E +N D L+ ++ + S QS + + + +++LE +
Sbjct: 6077 LIEETNRKDM-VLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKE 6135
Query: 1219 ----------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKE 1070
E K E E+ + MN + + L + L+ ++ K KE
Sbjct: 6136 NTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKE 6195
Query: 1069 DLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQL 890
++ QL S L + N M ++N +K+L KD+ + E Q + +
Sbjct: 6196 IIMKARSQLDRRQSELDKQQTNMNDIME----TMKNERKQL--DKDKEEMEE-QKQEMEK 6248
Query: 889 ELKHANMSICSLSEKIQQIEEREKVL---LTQLSTKDTDMQHLAAQLTLAQEEISSTKEM 719
E + + S SL E ++ ++ +++V+ +L +++ A + +EE + +++
Sbjct: 6249 ERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQI 6308
Query: 718 LKDFIDNME---------ASDTNLQSHFNQIQEM-LLNQNVNYPLEATVNIGFDQSMDEA 569
L+ + ++ A DT + N + EM + N++ L+ +++E
Sbjct: 6309 LEKMAEELKKERKDVAHLAEDTKREK--NSLDEMKVANESSMADLQKE-----KSNLEEM 6361
Query: 568 VSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
I +K TEDI E +++E+ +LQ+++ QS ++ K
Sbjct: 6362 KENI------SKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEK 6404
Score = 84.0 bits (206), Expect = 3e-13
Identities = 137/676 (20%), Positives = 281/676 (41%), Gaps = 48/676 (7%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDL-DIEQKLSTDRQSEIYSLS-AELER---ITQ 2078
L R DI+K E K ++ + +L D + +L DR + ++ EL+R + +
Sbjct: 9058 LQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRE 9117
Query: 2077 SEQMSLKRLKEAEQTLL---EAESERESLK-------------AELEESISVLKQELSSA 1946
+E + K L++ EQ + + E++ E+L+ A+ E++ +Q+L
Sbjct: 9118 TEDLERKILQQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLL 9177
Query: 1945 RLQIESLEKELNQA--NEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFD 1772
+ ++S E EL EE K L + + + E + ++S ++ +Y + +L
Sbjct: 9178 QGALQSQESELENRVFMEEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQR 9237
Query: 1771 KKNEITCLQEVIEQKEVE--------ERQRECMLAASERSNDINVNALEKKLSA---YEG 1625
+K ++ + IEQ++ + ERQ E + D NALEK S +
Sbjct: 9238 EKEQLEISKNQIEQEKKDLQNMKSNLERQLESLRHEKANVED-EKNALEKMRSESKEIQN 9296
Query: 1624 KIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARH 1445
IR+ D+ + ++ +EE+ ++ + ++++++ L++ R + ++ +
Sbjct: 9297 AIRKEREDLENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINN 9356
Query: 1444 NVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXX 1265
+EE + + K ++E + D E + D K
Sbjct: 9357 KMEELLQMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQE--- 9413
Query: 1264 XXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDI 1085
+ E K + +E K L E+ + + EM + +G +
Sbjct: 9414 ------------KEREIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLL 9461
Query: 1084 LKYKEDLLLNHGQLRAEMSSL---KIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAE 914
K K++L +L +M L K E E+ + +E+++KE I K++ + +
Sbjct: 9462 EKEKQELKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEK 9521
Query: 913 GQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTK-DTDMQHLAAQLTLAQEE- 740
+ QL++ L+++ ++ ++EK L Q + + Q L T EE
Sbjct: 9522 SNIEEMQLKIFKQQR----LNDQTREENKKEKESLEQQRFETEQQKQMLEISTTKMMEEK 9577
Query: 739 -----ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMD 575
+S + KD ++ + A TN + H + + L+ + +E I D+
Sbjct: 9578 NEMADLSRELQKAKDELEKI-AYKTNKERHEVEQMQAELHSQIQ-AIEQQGQIMQDKQNH 9635
Query: 574 EAVSEIAVQTFPNK---DTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTK- 407
E+++Q + + E H ++ EE K Q +E +++ +++ KQ+N K
Sbjct: 9636 LEEKELSIQRKEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQKNNKD 9695
Query: 406 LELLAKKTSEMDPEKY 359
ELL K SE++ EKY
Sbjct: 9696 FELLEKIRSELENEKY 9711
Score = 80.5 bits (197), Expect = 3e-12
Identities = 122/645 (18%), Positives = 264/645 (40%), Gaps = 32/645 (4%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELER--------- 2087
+++ D+QKEK+ E+++E + D + E++ R+ E+ L AE+ +
Sbjct: 4641 ESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQLQAEIHKQQGEIKMEK 4700
Query: 2086 -ITQSEQMS-LKRLKEAEQTLLEAESERESLKAE---LEESISVLKQELSSARLQIESLE 1922
+SE+ + +K +K+ + + + + ESLK + E VLKQ + + + E +E
Sbjct: 4701 SNNESERAAIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIE 4760
Query: 1921 KELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQE 1742
K + + + + + Q+ + + L + ++ + ++ +K I ++
Sbjct: 4761 KIKLETQHDRQRVEEMTAQIQKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRD 4820
Query: 1741 VIEQKEVE-ERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSA 1565
++E+++ + E+ R +L A E LEK+ +I++ D+ ++
Sbjct: 4821 MLEKEKHDLEKTRSKLLRAKEN--------LEKQRKIKLAEIQKEREDLEKMNEKFTIEI 4872
Query: 1564 GVFKEESTKVSNACD----LLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLK 1397
K + ++ D L EI+N +E+ E ++ +++ S + K +
Sbjct: 4873 HDIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNVN 4932
Query: 1396 SQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEE 1217
+ET + L + + E K + D D +Q LE+E+
Sbjct: 4933 DIMETMKN-ERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEK 4991
Query: 1216 CKSKQME-EYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDIL-------KYKEDLL 1061
K +QM+ E + E+ + E + ++ D+ + +++
Sbjct: 4992 SKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDEMK 5051
Query: 1060 LNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELK 881
+ + A++ K L E + DVEN ++ L + +D + + Q E++
Sbjct: 5052 VANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQREIE 5111
Query: 880 HANMSICSLSEKIQQIEEREKVLLTQLSTKDT-DMQHLAAQLTLAQEEISSTKEMLKDFI 704
EKI ER ++ KD D+QH L E + +E ++
Sbjct: 5112 ---------KEKINIESERAAII------KDVEDLQHKIICLDRDAESLKLDREAFENEK 5156
Query: 703 DNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTE 524
+ ++ T L+ ++I+++ L Q + V E+A Q KD +
Sbjct: 5157 EVLKQMKTELEREADEIEKIKLE---------------TQHDRQRVEEMAAQI--QKDRD 5199
Query: 523 DINTEIAHTSDKD----EEVIKLQSQVENLQSLVQMLKQQNTKLE 401
+IN I T+ KD E+ ++ +++++QS ML+++ LE
Sbjct: 5200 EINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLE 5244
Score = 79.7 bits (195), Expect = 5e-12
Identities = 122/685 (17%), Positives = 295/685 (43%), Gaps = 64/685 (9%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
+I+KEK KE + + + +I + T+R+ E+Y + +ELER+ K+L +
Sbjct: 10851 EIKKEKE-----KENEEEEEEEEEIRVIVETERK-ELYQIKSELERVRSEIDHEQKKLND 10904
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSA--RLQIESLEKELNQANEEV--KVLSK 1877
+ + + + + E +K+E+ + +++E S ++Q +LEK + ++E+ K++ +
Sbjct: 10905 YMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVE 10964
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECM 1697
Q +++ ++L + K+ ++ + ++ +NE +++V E+ +++RE +
Sbjct: 10965 VEEQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKKVDEE---IKKERETL 11021
Query: 1696 LAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDL 1517
R +I++ +++L + + +R + D+ +++ ++ E+ + N DL
Sbjct: 11022 -----REMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDIN-------EQKLHLKNQRDL 11069
Query: 1516 LQEIENFLREIRVETKVTIQEARHNVEEFSSVV--KHLEYLKSQLETSNTMDHDTLSSTH 1343
L+ + R E + + + ++EF + V + + K ++E +T +
Sbjct: 11070 LE-------QEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARII 11122
Query: 1342 QGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECK---SKQMEEYKMLQAE 1172
+ M+ KA Q + + + + EE + + EE +++E
Sbjct: 11123 E--MKTKAELQEIMQEKEEE------------------DEEEMRVIVEMEREELNQIKSE 11162
Query: 1171 LNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSL---------- 1022
L S ++ E K + + D+ K K +++ Q+ E S L
Sbjct: 11163 LKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLE 11222
Query: 1021 KIELVEKNGFMGYAVLDVENVQKELLIWK-----DRAMIAEGQSKAFQ--LELKHANMSI 863
+ ++ + ++ VE +K++ + K +R IA+ Q Q +L++ N I
Sbjct: 11223 RHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERI 11282
Query: 862 CSLSEKI---------------QQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISST 728
+ E+I ++ EE V+ K D++ ++ + +++ +
Sbjct: 11283 KEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDVNKQNQDLMNQ 11342
Query: 727 KEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEA---VSEI 557
+++LK + + T LQ ++ + Q + +S++E + E+
Sbjct: 11343 RDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEM 11402
Query: 556 AVQTFP-----NKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLV-----------QML 425
+T P K+ E+ A K EE+ +++SQ+E ++S + +M+
Sbjct: 11403 KTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMI 11462
Query: 424 KQQNTKLEL----LAKKTSEMDPEK 362
+Q+ LE + K+ +M+ E+
Sbjct: 11463 EQEKEDLEKMKSEIMKQRQQMEEER 11487
Score = 78.6 bits (192), Expect = 1e-11
Identities = 129/680 (18%), Positives = 300/680 (44%), Gaps = 61/680 (8%)
Frame = -2
Query: 2227 LDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++IQKE+ I E LK + + DL+ E+ +++I SLS +L+ ++ E + R +
Sbjct: 3114 VEIQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI-SLSEDLKEQSEREGIDNTRTR 3172
Query: 2047 ----------------------EAEQTLLEAESER-ESLKAELEESISVLKQELSSARLQ 1937
E ++ ++E E ++ E +KAEL++ K EL + R
Sbjct: 3173 IKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNERQN 3232
Query: 1936 IESLEKELNQANEEVKVLSK--FRYQV----LELEEYSQQLSADLSKVHEDYSAALRQLF 1775
+E +L + E V+ L++ R QV +++E Q+ + + +K ++ L +L
Sbjct: 3233 LEEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQE--RVLIELK 3290
Query: 1774 DKKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVS 1595
+I +E +E + +EER++ + A ++ + L++ +S + I N
Sbjct: 3291 KTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDI---VNKTE 3347
Query: 1594 QLTLS----VDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFS 1427
QL L A +++++ +N ++ E + L + E +E +E S
Sbjct: 3348 QLRLREVELEQLQALIYRQQDEIEANRKAIINE-KYRLEGQKTEIDRLQREVNQMMEYAS 3406
Query: 1426 SVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSS-TGDNDPKAXXXXXXXXXX 1250
+LE KS++ + D + +G +E++ ++ + D K
Sbjct: 3407 KDRANLEKEKSEM-IAQKHQMDIELNKERGLIEERTQMLNTYEKEMDQKRTALEVEMKEL 3465
Query: 1249 XECRQNLENEECKSKQM--------EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLE 1094
+Q ++ E+ K +QM ++ K L+ + N + + + +L
Sbjct: 3466 KYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLAHLA 3525
Query: 1093 GDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAE 914
D + +++ + H A++ K L + M +++ +K++++ +D+ +
Sbjct: 3526 EDTKRKDDEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQQMQ 3585
Query: 913 GQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEIS 734
+ Q E+ SI + + + ++ + L+T+L+ + D++ ++ +E +
Sbjct: 3586 AEINRQQTEM-DTKKSI--IENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLTEKELLE 3642
Query: 733 STKEMLKDFIDNMEASDTNLQS---HFNQIQEMLLNQ---------NVNYPLEATVNIGF 590
S +++LK ++N++ ++S Q +E+L N+ ++ E I
Sbjct: 3643 SDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKL 3702
Query: 589 D-----QSMDEAVSEIAV-QTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQM 428
+ Q ++E ++I + + K ++I EI +++++ + Q +++ L++ +Q
Sbjct: 3703 ETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQN 3762
Query: 427 LKQQNTK-LELLAKKTSEMD 371
L+Q+ K E++ K SE+D
Sbjct: 3763 LQQELEKEKEIIMKDRSELD 3782
Score = 76.3 bits (186), Expect = 5e-11
Identities = 150/706 (21%), Positives = 304/706 (43%), Gaps = 71/706 (10%)
Frame = -2
Query: 2233 VRLDIQKEKNISEDLKET-------VKNLQSDLDIEQKLSTD--------------RQSE 2117
+++++QK+KN E+L+ T V+N + LD +QK D +SE
Sbjct: 13918 LQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSE 13977
Query: 2116 IYSLSAELERITQSEQMSLKRLKEAEQTLLE-----AESERESLKAE------LEESISV 1970
+ LS L Q EQ L+RL E E+ +E ESE++S++ E L+E + V
Sbjct: 13978 LNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIESEKQSIERERAELKRLKEEVEV 14037
Query: 1969 ------LKQELSSARLQIESLEKELNQANEEVKVL-SKFRYQVLELEEYSQQLSADLSKV 1811
L+Q+ + + + E LE E + EE+ L + + + EL+ ++++ A K
Sbjct: 14038 QHERTLLQQDKNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEA---KR 14094
Query: 1810 HEDYSAALRQLFD----KKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKK 1643
E+ L + + K E L+E I +K+ + ++ L + R + +L++
Sbjct: 14095 QEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQ-TSLDEI 14153
Query: 1642 LSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREI-RVET-- 1472
E + R LE V+ + V K E T S ++ + N ++E+ R++T
Sbjct: 14154 TKTDERRQRALEETVA----TTAKQPIVIKLEDTLTSEVQEMRDHLNNEIKELARMKTIM 14209
Query: 1471 ---KVTIQEARHNV----EEFSSVVKHLEYLKSQLE---TSNTMDHDTLSSTHQGSMEDK 1322
K +++A+ ++ EEF ++ KS+ E T D + LS+T +
Sbjct: 14210 KMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLD---KKN 14266
Query: 1321 ASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNA 1142
+++T K + ++N+ENE + KQ+E+ + +Q + + ++
Sbjct: 14267 KEIENNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQIEQEREIQRKAD--VTSTEK 14324
Query: 1141 EMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVE- 965
EM Y E + YK +L + +++ + S +EL + + + +
Sbjct: 14325 EM-----------YTEK--VTYKTELEDSKEKIKPDRDS-TLELTDTDSAKTDGEREAQT 14370
Query: 964 ---NVQKELLIWKDRAMIAEGQSKAFQ------LELKHANMSICSLSEKIQQIEEREKVL 812
VQ L + D E + LEL A + L E+ + EE + V+
Sbjct: 14371 LETKVQDVLQLTDDTTQDQEELHDEMENKMKIILELNKAKKDLQKLKEECRSAEEEKSVI 14430
Query: 811 LTQLSTKDTDMQHLAAQ-LTLAQE--EISSTKEMLKDFIDNMEASDTNLQSHFNQIQEML 641
+ L + ++ + ++ L+L QE ++ K ++ M+ ++ + + ++
Sbjct: 14431 MESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWE--TDVQ 14488
Query: 640 LNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKD-EEVIKLQ 464
+ Q P+E T +I +S +E ++ Q K + + +E+ D + E+V +++
Sbjct: 14489 IQQEGQEPIETTGHI-TKKSEEEISAKKTKQPIVTKLEDTLTSEVQEMRDMEIEDVARMK 14547
Query: 463 SQVENLQSLVQMLKQQ-NTKLELLAKKTSEMDPEKYFHFEELCQSL 329
+ ++ + ++ K ++E + E EK + E L Q L
Sbjct: 14548 TMMKMEKDQLEQAKSDIQRQMEEFERNMEETLKEKSRNEETLLQLL 14593
Score = 75.9 bits (185), Expect = 7e-11
Identities = 131/629 (20%), Positives = 268/629 (42%), Gaps = 25/629 (3%)
Frame = -2
Query: 2227 LDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++IQKE+ I E LK + + DL+ E+ +++I SL ELE ++ E + R++
Sbjct: 2720 VEIQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI-SLREELEEQSEKEGIDKTRVR 2778
Query: 2047 EAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRY 1868
+Q + E E R ++ ELE + + KQ + R +IE ++ EL +E K K R
Sbjct: 2779 -IKQEMDELEQTRLNVVKELENN-ELQKQIIEDERDKIEQIKAEL---QKEAKDTEKQRQ 2833
Query: 1867 QVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIE------QKE------ 1724
+ ++++ L +D + ++ D++ + L++ +E +KE
Sbjct: 2834 DIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDLKK 2893
Query: 1723 --VEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
E + E L + R ++I + ++K+ E +L+ +S+ ++ F++
Sbjct: 2894 TNTEMKDLEKQLESQNRQHEIQLAEIQKEREILE----QLKLTLSKQKEDLEKERDCFEK 2949
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFS-SVVKHLEYLKSQLETSNT 1373
E +S +L ++ E RE +T+V I++ +++ +VVK LE +N
Sbjct: 2950 EKADISLREELQEQSE---REGIGKTRVRIKKEMDELKQTRLNVVKELE--------NNE 2998
Query: 1372 MDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEE 1193
+ + + KA Q D + + E L+NE+ K +
Sbjct: 2999 LQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEK-KDIETST 3057
Query: 1192 YKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIE 1013
++ E N + E + +++ D+ K K ++ QL +++ +I+
Sbjct: 3058 DRIRDEEANLEVQKQRLESDR-----DTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQ 3112
Query: 1012 LVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELK--HANMSICSLSEKIQ 839
LVE +QKE I + + Q + + E + SLSE ++
Sbjct: 3113 LVE--------------IQKEREILEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLK 3158
Query: 838 QIEEREKV--LLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSH 665
+ ERE + T++ + +++ L QE K++++D D +E L+
Sbjct: 3159 EQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKE 3218
Query: 664 FNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEI---AHTS 494
+ + L N+ N EA + D+ E+++E + + I TE+ A+ S
Sbjct: 3219 AEKTKLELQNERQNLE-EAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANES 3277
Query: 493 DK---DEEVIKLQSQVENLQSLVQMLKQQ 416
+K + +I+L+ V ++ + L+ Q
Sbjct: 3278 NKQMQERVLIELKKTVTDIAGAKEDLENQ 3306
Score = 75.9 bits (185), Expect = 7e-11
Identities = 137/684 (20%), Positives = 276/684 (40%), Gaps = 75/684 (10%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L ++ ++ KEK E++K+ VK + ++ E++ + + + I +
Sbjct: 8981 LQQMKNELNKEKEQVEEMKQMVKTERVKIEQEKE----------EMRKQTQEIEDGHEKL 9030
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVL 1883
K+ + A++ L +A SE + LK +L + + +Q++ ++E+ ++ L++ + E+
Sbjct: 9031 QKKTEIADKLLQDANSESDRLK-DLSMKLQMQRQDIEKTNTEMETKKRSLDRMSREL--- 9086
Query: 1882 SKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRE 1703
Q L + Y + L K+ E+ E +E+K +++R+++
Sbjct: 9087 --------------QDDKIRLKNDRDAYEKDMTHLELKREELVRETEDLERKILQQREQD 9132
Query: 1702 CMLAASERSNDINVNALE-------KKLSAYEGKIRRLENDVSQLTL--------SVDFS 1568
M ++R + ALE KK + + ++ + ++ +L L +
Sbjct: 9133 EM---AKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQESELE 9189
Query: 1567 AGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQL 1388
VF EE + A +E L E+ E R +EE + LE K+Q+
Sbjct: 9190 NRVFMEEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQREKEQLEISKNQI 9249
Query: 1387 ETSNTMDHDTLSSTHQGSME----DKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLEN- 1223
E D + S + +E +KA+ + + + R++LEN
Sbjct: 9250 E-QEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENC 9308
Query: 1222 ---EECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNH 1052
E + K+MEE + +++E+ K ++ E I E+LL
Sbjct: 9309 WVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSR---ENIESREEKINNKMEELL--- 9362
Query: 1051 GQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDR------AMIAEGQ------ 908
Q++ EM K E+ +++ + A +D+EN + E+ +D+ I E +
Sbjct: 9363 -QMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQ 9421
Query: 907 --------SKAFQLELKHANMSICSLSEKIQQIE------EREKVLLTQLSTK-DTDMQH 773
S+ +L++K M + + + Q+IE E+EK L Q + + M
Sbjct: 9422 LDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMD 9481
Query: 772 LAAQLTLAQEE---ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLL----NQNVN--- 623
L + +EE + + K L+D E L + I+EM L Q +N
Sbjct: 9482 LTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQT 9541
Query: 622 -----YPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTE--DINTEIAHTSDKDEEVI--- 473
E+ F+ + + EI+ + E D++ E+ D+ E++
Sbjct: 9542 REENKKEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDELEKIAYKT 9601
Query: 472 -KLQSQVENLQ----SLVQMLKQQ 416
K + +VE +Q S +Q ++QQ
Sbjct: 9602 NKERHEVEQMQAELHSQIQAIEQQ 9625
Score = 75.1 bits (183), Expect = 1e-10
Identities = 131/671 (19%), Positives = 280/671 (41%), Gaps = 33/671 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD ++ ++Q E E++K + +++++ EQ+ + I +LE + +
Sbjct: 9952 LDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGDLEIMRADYE-- 10009
Query: 2062 LKRLKEAEQTLLEAESERESL---KAELEESISVLKQELSSARLQIESLEKELNQANEEV 1892
K+ ++ E+ +EA+ ER+ L K+ELE+ + + E +EKE N
Sbjct: 10010 -KQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKERNDLE--- 10065
Query: 1891 KVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQ--KEVE 1718
K+ S+ Q ++E+ +L + + + + K++I +E++E+ EVE
Sbjct: 10066 KMKSELMTQRQQMEDERSELDQKIKEANTE-----------KDKIEKNKEIVERLMAEVE 10114
Query: 1717 ERQRECML----AASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
E++ + L A ER N ++ L L+ E +++ + + E
Sbjct: 10115 EQRNDFKLKKEELALERQNIVDEKYL---LAQCETELQNKSEQIRNM------------E 10159
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTM 1370
E+ K N + L+E E L+ + E K I+E E+ + + K +L+
Sbjct: 10160 EAVK--NERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKK-- 10215
Query: 1369 DHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEY 1190
DTL + Q + D + R+ E + K+MEE
Sbjct: 10216 --DTLEQEREEINHKWTQFQQRIDEFDAQV-------------RKQKEEDLTNQKKMEEE 10260
Query: 1189 KMLQAELNNWLSCMNA----EMGKFLCLCNSMVYLEGDILKYKED---LLLNHGQLRAEM 1031
+ E+N + M E + + L+ I+K KE + + R ++
Sbjct: 10261 RKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAMTIKLKMEREDL 10320
Query: 1030 SSLKIELVEKNGFMGYAVLDVENVQKEL-----LIWKDRAMIAEGQSKAFQLELKHANMS 866
+K ELV + +V++ QK+L +I +++ + + +S+ + +
Sbjct: 10321 DQIKSELVREK-------TEVDHEQKKLNDDIKMIEQEKEDLEKMKSE-IMTQKQEMEKE 10372
Query: 865 ICSLSEKIQQIE------EREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFI 704
L KIQQ + E+ K ++ +L + + +H ++ L +EE+ ++ + D
Sbjct: 10373 RSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRH---EIQLQKEELDIERQKIADEQ 10429
Query: 703 DNMEASDTNLQSHFNQIQEMLLNQNVNYPLEA--TVNIGFDQSMDEAVSEIAVQTFPNKD 530
D + + + LQ+ +I+ +N+ + E + ++ +E S +D
Sbjct: 10430 DLLIQNKSELQNENERIRN--INEVIKKERETLKEMEAHLEKEKEEMKSITEETRRQKED 10487
Query: 529 TEDINTEIAHTSDKDEEVIK----LQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEK 362
E ++T+I +++++++K L+ + E++ L+Q+ + + K E D K
Sbjct: 10488 LEKMSTDI---KEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQVSKQKEEDLTK 10544
Query: 361 YFHFEELCQSL 329
+E +SL
Sbjct: 10545 QKEMKEERKSL 10555
Score = 75.1 bits (183), Expect = 1e-10
Identities = 132/702 (18%), Positives = 287/702 (40%), Gaps = 68/702 (9%)
Frame = -2
Query: 2245 TLDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLST-------DRQSEIYSLSAELER 2087
TL + ++KEK + + E + + DL +K+ST D +S+ L E E
Sbjct: 11851 TLKEMEAYLEKEKEEMKSITEETRRQKEDL---EKMSTHINEQKQDLRSQRDLLEQEREE 11907
Query: 2086 ITQSEQMSLKRL--------KEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIE 1931
I + +R+ K+ E+ L + + +E K+ E ++L+ + + + E
Sbjct: 11908 INHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMK---TKAEPE 11964
Query: 1930 SLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITC 1751
++KE + EE ++ K + E+E Q+ + L +V + ++L D K I
Sbjct: 11965 EIKKEKEKEEEEQEMRVKVEMERKEIE----QIKSQLERVRSEMDHEQKKLNDDKKMIEQ 12020
Query: 1750 LQEVIE--QKEVEERQRECMLAASERSNDINVNALEK-KLSAYEGKIRRLENDVSQLTLS 1580
+E +E + E+ +++++ SE I LEK + + + +L +V +
Sbjct: 12021 EKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHE 12080
Query: 1579 VDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYL 1400
+ F E K+++ DLL ++ K+ Q ++E +K
Sbjct: 12081 IQFQKEELDIERQKIADEQDLL-----------IQNKIEQQNENERIKEMDEEIKKERET 12129
Query: 1399 KSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE 1220
++E + + + + S + + K + + D + + +Q+L N+
Sbjct: 12130 LKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQ--------------KQDLMNQ 12175
Query: 1219 ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGD-----------ILKYK 1073
KQ E E+N+ L+ + + +F N +V + + +K
Sbjct: 12176 RDLLKQERE------EMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEY 12229
Query: 1072 EDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQ 893
E ++ + R E+ ++++ ++N + +E +K+ K+R E Q +A
Sbjct: 12230 ESIIEETNRKRTELEEIEVDQSQQNKNVETMKDLLEKERKD--TEKER---EELQKQADD 12284
Query: 892 LELK------HANMSICSLSEKIQQIEEREKVLLTQ---LSTKDTDMQHLAAQLTLAQEE 740
LE++ MS SL E+ + +E++ +L Q L + DM +L Q+E
Sbjct: 12285 LEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKE 12344
Query: 739 ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSE 560
I + K +++ +E + +++E L N V + +++ + + E
Sbjct: 12345 IQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKHQQQ-IEE 12403
Query: 559 IAVQTFPNKDTED----------------------INTEIAHTS---DKDEEVIKLQSQ- 458
+ V+T +D D + E+ T D EE +KL+ Q
Sbjct: 12404 MRVKTKMERDELDQLMAKMLMDRKENERSKDMIGLLKKEMEQTKFNLDAQEEELKLEKQK 12463
Query: 457 VENLQSLVQM----LKQQNTKLELLAKKTSEMDPEKYFHFEE 344
++N + ++M +K++ ++++ L ++ E D + + +E
Sbjct: 12464 IQNEKKDLEMFKAEIKREASEVKTLKEQQLEKDTKAFEALKE 12505
Score = 75.1 bits (183), Expect = 1e-10
Identities = 125/644 (19%), Positives = 282/644 (43%), Gaps = 28/644 (4%)
Frame = -2
Query: 2218 QKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELE-RITQSEQMSLKRLKEA 2042
+KEK+ +++ ++++S ++ +L T+ ++I +++EL+ R + E + K+ KE
Sbjct: 13368 RKEKHAEAEIQRQFEDIES---VKVRLVTE-SNQIDKMNSELKTRSEELENLIKKQQKEF 13423
Query: 2041 EQTLLEAESERESLK---AELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFR 1871
E E + ER++L+ AELE + LK ++ + L+KE N+ E +L + +
Sbjct: 13424 ETKENEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREK 13483
Query: 1870 YQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-----TCLQEV-IEQKEVEERQ 1709
++ + + QQ ++ + + + + L +NE+ + L + +E+ E+++ +
Sbjct: 13484 SELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLK 13543
Query: 1708 RECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSN 1529
E + + + S + L++ E K +L+N + ++ + + +E+ +
Sbjct: 13544 TE--IQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMD---KLSIQREKDSLEEI 13598
Query: 1528 ACDLLQEIENFLREIRVETKVT--IQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTL 1355
DL ++ E E+R ++T I + +++ + L +++ +E + L
Sbjct: 13599 KADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQAKI----L 13654
Query: 1354 SSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSK-QMEEYKMLQ 1178
S Q +K + S +ND R++LE + ++ ++E + +
Sbjct: 13655 ESDVQLLQTEKEILEKSKTEND--------------LLREDLEKQRKRNDLTLQELRKEK 13700
Query: 1177 AELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKN 998
L ++ + E L N V L+ LK KE L + R EM L+++L +
Sbjct: 13701 MALEQMITDITKEKDAVASLQNE-VSLKQHELKNKETEL---DEQRKEMDDLRMQLEMRQ 13756
Query: 997 GFMG-----YAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELK----HANMSICSLSEK 845
V VEN++ + + ++ E + + Q +K N+ S ++
Sbjct: 13757 NSTNKQQQEVDVFIVENMKMRNDLESMKTLLDE-ERRQLQDNIKTFEDQKNVLHPSKTDA 13815
Query: 844 IQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSH 665
+QQ +E EK T + T+ ++ ++ + +EI +KE L+ +E +
Sbjct: 13816 VQQTDELEK-FTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGK 13874
Query: 664 FNQIQEMLLNQNVNYPLEATVNIGFD--QSMDEAVSEIAVQTFPNKDTEDINTEIAHTSD 491
QI+ + L A + G D +++ + ++A++ K ++ + +
Sbjct: 13875 RAQIESL-------EQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKN 13927
Query: 490 KDEEVIKL----QSQVENLQSLVQMLKQQNTKLELLAKKTSEMD 371
+ EE+ + QVEN + + + KQQ +++ SE D
Sbjct: 13928 ELEELRNTIEAEKHQVENRK--IMLDKQQKEVEDIMTVIKSERD 13969
Score = 72.8 bits (177), Expect = 6e-10
Identities = 145/702 (20%), Positives = 296/702 (42%), Gaps = 82/702 (11%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSE--------- 2072
+IQKE+ I E LK T+ + DL+ E+ +++I SL EL+ ++ E
Sbjct: 2918 EIQKEREILEQLKLTLSKQKEDLEKERDCFEKEKADI-SLREELQEQSEREGIGKTRVRI 2976
Query: 2071 --------QMSLKRLKEAEQTLLE---AESER---ESLKAELE---ESISVLKQELSSAR 1943
Q L +KE E L+ E ER E +KAEL+ E ++++ R
Sbjct: 2977 KKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDR 3036
Query: 1942 LQIESLEKELNQANEEVKV-LSKFRYQVLELEEYSQQLSAD-----------------LS 1817
E + +L ++++ + R + LE Q+L +D +
Sbjct: 3037 RNNEEMVIKLQNEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKERFDLEKTKTEMG 3096
Query: 1816 KVHEDYSAALRQLFDKKNEITCLQEVIE--------QKEVEERQRECMLAASERSNDINV 1661
+ + + +RQ + EI +E++E QKE E++R+C + DI++
Sbjct: 3097 NLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCF---EKEKADISL 3153
Query: 1660 NALEKKLSAYEGKIRRLENDVSQLTLSVD----FSAGVFKEESTK------VSNACDLLQ 1511
+ K+ S EG ++N +++ +D + KE+ + + D ++
Sbjct: 3154 SEDLKEQSEREG----IDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIE 3209
Query: 1510 EIENFLREIRVETKVTIQEARHNVEEFSSVVK----HLEYLKSQLETSNTMDHDTLSSTH 1343
+I+ L++ +TK+ +Q R N+EE + +K ++E L +L + + T
Sbjct: 3210 QIKAELKKEAEKTKLELQNERQNLEEAGTKLKKDRENVESLAEELGRKQVVLENMQIET- 3268
Query: 1342 QGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNN 1163
M+ KA ++S+ + +++LEN+ + + E+ K+ QAE+
Sbjct: 3269 --EMQRKA-NESNKQMQERVLIELKKTVTDIAGAKEDLENQLLEER--EKNKVKQAEI-- 3321
Query: 1162 WLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQL----------RAEMSSLKIE 1013
AE L + + DI+ E L L +L + E+ + +
Sbjct: 3322 -----QAEKDMLYLLKQGISEQQVDIVNKTEQLRLREVELEQLQALIYRQQDEIEANRKA 3376
Query: 1012 LVEKNGFMGYAVLDVENVQKEL-----LIWKDRAMIAEGQSKAFQLELKHANMSICSLSE 848
++ + + +++ +Q+E+ KDRA + + +S+ + KH M I L++
Sbjct: 3377 IINEKYRLEGQKTEIDRLQREVNQMMEYASKDRANLEKEKSE--MIAQKH-QMDI-ELNK 3432
Query: 847 KIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQS 668
+ IEER ++ L+T + +M L + +E+ K+ +++ + ++ LQ
Sbjct: 3433 ERGLIEERTQM----LNTYEKEMDQKRTALEVEMKELKYHKQAIQEEKNKLQQMKIELQR 3488
Query: 667 HFNQIQEML-LNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSD 491
+ I+++ +N LE ++ D+ ++ +A T D + E A +D
Sbjct: 3489 EADDIKKLKEKTRNERQSLEKMAE-NLEKEKDD-LAHLAEDTKRKDDEMKVLHESA-LAD 3545
Query: 490 KDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPE 365
+E L+ E++ +M+ + K+ L K +M E
Sbjct: 3546 IQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQQMQAE 3587
Score = 70.9 bits (172), Expect = 2e-09
Identities = 105/631 (16%), Positives = 253/631 (40%), Gaps = 12/631 (1%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L+ V +IQ+EK + + + +L+ + +RQ +I + +LE E+
Sbjct: 9759 LNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLE-----EEKL 9813
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEES-ISVLKQELSSARLQIESLE---KELNQANEE 1895
L +++ + E +R+ K E+ E+ + V+K++ +AR + E + +E Q NE
Sbjct: 9814 LVQIEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNEN 9873
Query: 1894 VKVL-----SKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-TCLQEVIE 1733
K L Q EL++ + L + E+ + R L ++K + E++
Sbjct: 9874 AKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILR 9933
Query: 1732 QKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFK 1553
Q++ E+++E M+ KL + +++ + ++ +D
Sbjct: 9934 QRDDLEKEKEDMMKK------------WNKLDVLQNEMQNENKAMEEIKYELDGKRNEIN 9981
Query: 1552 EESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNT 1373
+E ++ + + E + L +R + + Q+ E K L+ +KS+LE T
Sbjct: 9982 KEQQRLEESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKT 10041
Query: 1372 -MDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQME 1196
+D++ + +M +K + ++ RQ +E+E
Sbjct: 10042 EIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQ------------RQQMEDE-------- 10081
Query: 1195 EYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKI 1016
++EL+ + N E K + L ++ + + D L +L E +
Sbjct: 10082 -----RSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQRNDFKLKKEELALERQN--- 10133
Query: 1015 ELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQ 836
+V++ + +++N +++ + + +K+ ++ +Q+
Sbjct: 10134 -IVDEKYLLAQCETELQNKSEQI--------------RNMEEAVKNERETLKETEAHLQR 10178
Query: 835 IEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQ 656
++ K ++ + S + D++ ++ + + ++E+ + K+ L+ + + T Q ++
Sbjct: 10179 DKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDE 10238
Query: 655 IQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDE-E 479
+ Q ++ + M+E K E++N +I K E E
Sbjct: 10239 FDAQVRKQKEE-------DLTNQKKMEE----------ERKCLEEVNGKIIEMKTKAELE 10281
Query: 478 VIKLQSQVENLQSLVQMLKQQNTKLELLAKK 386
++ ++E LQ+L + + ++ K E + K
Sbjct: 10282 HHEINQKIEELQTLQEQIMKEKEKAEAMTIK 10312
Score = 70.5 bits (171), Expect = 3e-09
Identities = 135/717 (18%), Positives = 295/717 (41%), Gaps = 94/717 (13%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKETVKNLQSD-------LDIEQKLSTDRQSEIYSLSAELERIT 2081
D R DI+ K I + L V+ + D LDIE++ D Q + A+L+
Sbjct: 11498 DLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNEN 11557
Query: 2080 QSEQMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQAN 1901
+ + + +K+ ++TL E E+ L+ E EE SV+++ + +E + ++N+ N
Sbjct: 11558 ERIKEMDEEIKKEKETLKEMEAH---LRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQN 11614
Query: 1900 EEV----KVLSKFRYQV----LELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQ 1745
+++ +L + R ++ +L++ + A +SK E+ +++ +++ + +
Sbjct: 11615 QDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETK 11674
Query: 1744 -EVIE----------QKEVEERQRECMLAASERSND-------------INVNALEKKLS 1637
++IE +KE E+ + E M A E + ++ +KKL+
Sbjct: 11675 IKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLN 11734
Query: 1636 AYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSN--------ACDLLQEIENFLREIR 1481
+ I + + D+ ++ + +EE +++ N CD IEN +EI
Sbjct: 11735 DDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCD----IEN-SKEIV 11789
Query: 1480 VETKVTIQEARHNVE--------EFSSVVKHLEYL---KSQLETSN----------TMDH 1364
+ V ++E +H ++ E + + L KS+L+ N +
Sbjct: 11790 QKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKER 11849
Query: 1363 DTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEE--- 1193
+TL ++K +S T + + E +Q+L ++ +Q E
Sbjct: 11850 ETLKEMEAYLEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEIN 11909
Query: 1192 --YKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLK 1019
+K LQ ++ + + ++ + + L M + + K ++L + +AE +K
Sbjct: 11910 HKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANIL--EMKTKAEPEEIK 11967
Query: 1018 IELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQ 839
E EK + VE +KE+ K + + Q +L I E ++
Sbjct: 11968 KE-KEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLE 12026
Query: 838 QIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFN 659
+++ Q+ + +++ Q L + +I ++KE+++ + +E +Q
Sbjct: 12027 KMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKE 12086
Query: 658 QI----------QEMLLNQNVNYPLEATVNIGFDQSMD---EAVSEIAVQTFPNKDTEDI 518
++ Q++L+ + E D+ + E + E+ V K+ E+I
Sbjct: 12087 ELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNL--QKEKEEI 12144
Query: 517 NTEIAHTSDKDEEVIKLQS----QVENLQSLVQMLKQQ----NTKLELLAKKTSEMD 371
+ I T + E++ K+ + Q ++L + +LKQ+ N KL L ++ E +
Sbjct: 12145 ESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFE 12201
Score = 67.4 bits (163), Expect = 3e-08
Identities = 132/650 (20%), Positives = 266/650 (40%), Gaps = 34/650 (5%)
Frame = -2
Query: 2224 DIQKEK-NISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
+I EK NI + ++ Q+ + +K S D + ++ + E E + + K ++
Sbjct: 6659 EIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVE 6718
Query: 2047 EAEQTLLEAESERESLKAE---LEESISVLKQELSSARLQIESLEK-ELNQANEEVKVLS 1880
+ +Q L+ E + ESLK + E +KQ + ++Q + +EK +L +E +V
Sbjct: 6719 DLQQKLMSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRV-- 6776
Query: 1879 KFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-TCLQEVIEQKEVEERQRE 1703
++ +A + K E+ + + ++ K++ I E+ ++KE E R
Sbjct: 6777 -------------EEKTAQIQKEREEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRS 6823
Query: 1702 CMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNAC 1523
+ A ++ N N +E L+ + K LE +S + S K E
Sbjct: 6824 DLEKAKSQTFKQNKN-IEIALAEIQQKRNALEK------MSKEISRDRMKLE-------- 6868
Query: 1522 DLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTH 1343
+ K IQ AR +E ++ + K L S D L +
Sbjct: 6869 ---------------DEKKEIQLAREELERMHGDMQRQQEAKDHL-LSGITDESLLKKSE 6912
Query: 1342 -----QGSMEDKA----SSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEEC-------- 1214
Q S DKA ++ S D P +++ E+E+
Sbjct: 6913 AEIVLQPSQVDKAKPARKTEISDSDKQPVFVQQMPEMDLKDALKKDFESEKLDLPKVKDV 6972
Query: 1213 --KSKQME-EYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQL 1043
+ +QM+ E K+++ E++ L M AE+ K E D ++ K+ + N Q
Sbjct: 6973 LPQDQQMKLEQKLIEDEMDK-LKQMRAELQK-----------EADQIEKKKQDMQNERQK 7020
Query: 1042 RAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLE---LKHAN 872
+M++ E N E + +E+ I K + + Q+ AFQ+E +
Sbjct: 7021 LDDMAARLQEERRTN----------ERLNEEINIQK---VNQQKQATAFQMEKTDFERIK 7067
Query: 871 MSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNME 692
I ++++ +E+ K +T++ + ++ + A ++ E I++ + L
Sbjct: 7068 TEIDQANKELADQQEKNKKTITEMQKERETLEEMRANISKQVETITNENKSL-------- 7119
Query: 691 ASDTNLQSHFNQIQEMLLNQNVNY-PLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDI- 518
++ +S ++QE +L Q L+ T+ + Q +D+ S+I + K+ +D+
Sbjct: 7120 ---SSRESELAKLQEDILQQQQEMDELKNTIMMEMCQ-LDQRQSDIDLL---QKEVDDLM 7172
Query: 517 ---NTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSE 377
TE+A+ + E +++ +Q N++S + LK + E L K +E
Sbjct: 7173 DFTKTEMANV---ERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNE 7219
Score = 67.0 bits (162), Expect = 3e-08
Identities = 116/631 (18%), Positives = 263/631 (41%), Gaps = 25/631 (3%)
Frame = -2
Query: 2188 KETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTLLEAESER 2009
+E + +++++DIE+ + + ELE+I Q +AE E
Sbjct: 12977 REELAKMKTEIDIERDEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQHDEIHGGI 13036
Query: 2008 ESLKAELEESISVLKQELSSARLQIESLEKELNQANEEV-KVLSKFRYQVLELE--EYSQ 1838
+SLK E EE I +K +L + + E++ + + +E+ K ++ +E E + +
Sbjct: 13037 DSLKEEREE-IEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDK 13095
Query: 1837 QLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVN 1658
L ++ K+ A L+ +KN + + E + +E E + C + E++ ++N
Sbjct: 13096 NLQDEMMKI----EAILKVTKKQKNYLEQMNENL-TREKTELETNCQMLEREKT-ELNKK 13149
Query: 1657 ALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRV 1478
E + + K+ E + + +D A EE K+ +E+ N EI+
Sbjct: 13150 VKETE-EFHMSKMEEREAERKTIERVMDEMA----EEHEKIKKE---REELVNMEEEIKK 13201
Query: 1477 ETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTG 1298
+ +V ++ E + L++ +S+L D ++S + ++ + S Q
Sbjct: 13202 QRRV----LEESMNEMTKKKSELQHERSELYKQKQQLEDMIASESKRDVDTERSRQDKED 13257
Query: 1297 DNDPKAXXXXXXXXXXXECRQNLENEECK---SKQMEEYKMLQAELNNWLSCMNAEMGKF 1127
+ K ++ + E K +++ E + +Q++LN+ M+ E K
Sbjct: 13258 EQILKREREEIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKL 13317
Query: 1126 LCL-------CNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDV 968
L + N++ + D+ K +E++ Q + E I + E +A ++
Sbjct: 13318 LYMKTEIQVKTNALEKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEI 13377
Query: 967 ENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKD 788
+ +++ K R + Q ELK + SE+++ + ++++ + TK+
Sbjct: 13378 QRQFEDIESVKVRLVTESNQIDKMNSELK-------TRSEELENLIKKQQ---KEFETKE 13427
Query: 787 TDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEM--LLNQNVNYPL 614
+MQ L E+ LK+ I+ + + +LQ N+ +E+ +L + +
Sbjct: 13428 NEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREKSELY 13487
Query: 613 EATVNIGFDQSMDEAVSEIA------VQTFPNKDTEDINTEIAHTSDKDEEVIKL----Q 464
+ + + E + + ++ N+ ++ + ++ S + E+ KL Q
Sbjct: 13488 QEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTEIQ 13547
Query: 463 SQVENLQSLVQMLKQQNTKLELLAKKTSEMD 371
S+ E+++ + LKQ + E K +++D
Sbjct: 13548 SEKESIEEEKKTLKQLKDENE---SKRTQLD 13575
Score = 65.9 bits (159), Expect = 7e-08
Identities = 135/678 (19%), Positives = 282/678 (41%), Gaps = 63/678 (9%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKE-------TVKNLQSDLDIEQKLSTDRQSEIYSLSAELERIT 2081
D + I KEK S ++E T + + +++ E++ RQ E+ E+ERI
Sbjct: 546 DVEKAKILKEKEESIRIREEARQERETTELVNAEIKAEKERLNQRQEEMLRERQEIERIK 605
Query: 2080 QSEQMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQAN 1901
+ + ++ ++ + + E +KAE++ I +++++ + E +E+ +
Sbjct: 606 HETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKEQMEEAKVELE 665
Query: 1900 EEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITC---------- 1751
EE + L + R V E ++ L ++ +V E+ + R+ ++ E+
Sbjct: 666 EEREDLERKRDLVSREIEQAEFLRNEILRVKEEMESRWRETETEEVELRAKTQHELERLE 725
Query: 1750 -LQEVIE--QKEVEERQRECML-------AASERSNDINVNALEKKLSAYEGKIRRLEND 1601
L+E E QK +EE + E ML E D +V ++ ++ + K +L
Sbjct: 726 KLREETERSQKNIEESKIELMLWKESLDKLKGEMEEDKHVVIMQ--MNEAKAKEEQLTMV 783
Query: 1600 VSQLTL---SVDFSAGVFKEESTKVSNACDLLQ----EIENFLREIRVETKVTIQEARHN 1442
+ QL + + S KEE +++ + LQ E+E++ R + E K A+
Sbjct: 784 IEQLEIERGEITISREKVKEELDEINRMRNELQRQHAEMEDWFRVVNKE-KEEANLAKLA 842
Query: 1441 VEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXX 1262
V E + LK Q+E S ++ ++ ++E + Q KA
Sbjct: 843 VHEAEML------LKKQMEESEKRRYEMITE----ALEQRDEIQK-------KAEELEQI 885
Query: 1261 XXXXXECRQNLE-----NEECKSKQME---EYKMLQAELNNWLSCMNAEMGKFLCLCNS- 1109
RQ LE +E K +E + ++ ++ + L A+ K L +S
Sbjct: 886 NKEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLFEMDSE 945
Query: 1108 ---MVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLI- 941
+ + + K+DL Q R EM VE++ + ++E ++ +L+I
Sbjct: 946 RKELEQMRFQVENEKKDL----EQRRYEMMRYD---VEQSAQVQRQKEELEKIKSQLVID 998
Query: 940 ----WKDRAMIAEGQSKAFQL--ELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDM 779
+ R + + + KA L E++ + E+ +Q EE ++L + + D+
Sbjct: 999 TESMNRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRLLRKDMENEREDL 1058
Query: 778 QHLAAQLTL--------AQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVN 623
+ + + TL +EEI+ + ++ D E D + N +E ++ +
Sbjct: 1059 EKIRVE-TLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRK--- 1114
Query: 622 YPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIK--LQSQVEN 449
+EA + M E + ++ V+ K+ D+ E A + E++K L Q E+
Sbjct: 1115 --MEA-----MKREMGE-IEDMKVELTKQKENIDMKMEHARLEMTNLEMMKADLLRQKED 1166
Query: 448 LQSLVQMLKQQNTKLELL 395
+++ + K + ++E++
Sbjct: 1167 IENQMLAAKSERQQMEVM 1184
Score = 65.5 bits (158), Expect = 1e-07
Identities = 142/774 (18%), Positives = 319/774 (41%), Gaps = 66/774 (8%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
+++ ++ + ED K ++N++ +L E + ++ +E + + + L++
Sbjct: 1805 NLEAQRKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEK 1864
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQ 1865
+ + ++ER +LE + + L+ + + + LEK +++ N + K +
Sbjct: 1865 KRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEK-ISELNSQQKDEIENEKS 1923
Query: 1864 VLELEEYS-QQLSADLSKVHEDYSAALRQLFDKKNEITCLQ-EVIEQ-KEVEERQRECML 1694
+++ EY QQ+ DL++ ++ +F +K+E+ Q E+ EQ K+V + +
Sbjct: 1924 KIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQDEIAEQLKQVGDMMQ---F 1980
Query: 1693 AASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLL 1514
+E+ N L+++ +A + ++E D++ L S + K+E V N LL
Sbjct: 1981 TQNEKDN------LDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKE---VLNEKRLL 2031
Query: 1513 QEIE-NFLREIR--VETKVTIQEARHNVE-EFSSVVKHLEYLKSQLET----SNTMDHDT 1358
++ + +R+++ + K+ ++ + ++ + S+ + + L+S L+T + + DT
Sbjct: 2032 EDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDT 2091
Query: 1357 LSSTHQGSMEDKA---------------SSQSSTGDNDPKAXXXXXXXXXXXECRQNLEN 1223
L+ + +ED A ++ D D + + +L+
Sbjct: 2092 LAEKQK--LEDAAVELQKERDEIMNIAEETKRKREDVDKIRVGIEKQEITFKDLKADLQK 2149
Query: 1222 E--------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKED 1067
E + K ++ K ++ ++ M+ + + ++ ++ ++ K +++
Sbjct: 2150 EAAIVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVDKERQE 2209
Query: 1066 LLLNHGQLRAEMSSLKIE------LVEKNGFMGYAV--------LDVENVQKELLIWKDR 929
+ +L E S L+ + EKN + + L EN+ KE I
Sbjct: 2210 VESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTI---- 2265
Query: 928 AMIAEGQSKAFQLELKHANMSICSLSEKIQQIEE------REKVLLTQLSTKDTDMQHLA 767
F+LE +H + K +QI+E EKV + Q+ D D Q
Sbjct: 2266 ----------FELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQA-DKDQQRKK 2314
Query: 766 AQL--------TLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLE 611
A+ T A EE E L++ +N+E + H N+ +E+ ++ + +E
Sbjct: 2315 AEYVKTARGRETTALEEQRQEMESLREEYENVEKQ----KKHVNEQKELFESRMKSLEME 2370
Query: 610 ATVNIGFDQSMDEAVSEIAVQ-TFPNKDTEDINTEIAHTSDKDEEVIK-LQSQVENLQSL 437
+ + +D+ ++ Q K+ + + TE+ ++ E K L+ Q + +
Sbjct: 2371 NEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTE 2430
Query: 436 VQMLKQQNTKLELLAKKTSEMDPEKYFHFEELCQSLVXXXXXXXXXXXXXXXKNQVLVKQ 257
ML+ Q +E KT E+D + +L S V + + VK+
Sbjct: 2431 TYMLETQKPVVE--KSKTDELDEVRKKINADL--SEVEKQKSALVQMNLKISQEESYVKK 2486
Query: 256 VKEMQVTLQSESPMEGETDSISENAIGSQPA--GKLSTELHNVHGNTERVPLQL 101
K+ ++E M+ + +N + + A K EL NV E+ +++
Sbjct: 2487 EKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEI 2540
Score = 65.5 bits (158), Expect = 1e-07
Identities = 135/673 (20%), Positives = 272/673 (40%), Gaps = 57/673 (8%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQ--------KLSTDR---QSEIYSLSAELERITQ 2078
D+QKEKN +E+LK ++ +S+L E+ ++ T R +SE+ +L +
Sbjct: 13464 DLQKEKNKTEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELED 13523
Query: 2077 SEQMSLKRLK----EAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELN 1910
++ L RL E ++ E +SE+ES++ E ++++ LK E S R Q+++ +++N
Sbjct: 13524 EKKSMLSRLSMEKHEIDKLKTEIQSEKESIEEE-KKTLKQLKDENESKRTQLDNTIEKMN 13582
Query: 1909 ----------QANEEVKVLSKFRYQVLELE-----EYSQQLSADLSKVHED--------- 1802
+ EE+K + + + L+ E + + Q+S D + +D
Sbjct: 13583 MDKLSIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRS 13642
Query: 1801 -YSAALRQLFDKKNEITCLQ---EVIEQKEVEERQRECMLAASERSNDINVNALEKKLSA 1634
+ RQ ++++ LQ E++E+ + E L + ND+ + L K+ A
Sbjct: 13643 MRADIERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEKQRKRNDLTLQELRKEKMA 13702
Query: 1633 YEGKIRRLEND---VSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVT 1463
E I + + V+ L V K + T++ + ++ L + T
Sbjct: 13703 LEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQ 13762
Query: 1462 IQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPK 1283
QE + E + LE +K+ L+ D + + S + D
Sbjct: 13763 QQEVDVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDEL 13822
Query: 1282 AXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMV 1103
+ E + +K++ + K LN + E+ S+
Sbjct: 13823 EKFTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLE 13882
Query: 1102 YLEGDILKYKED---LLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWK- 935
L D+L +D L+ Q+ E + K E VE + ++E ++ + K
Sbjct: 13883 QLRADLLAGADDIKTLVQTEKQMAIEDTEKKTE-VELQMNLQKQKNELEELRNTIEAEKH 13941
Query: 934 ---DRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAA 764
+R ++ + Q K + I ++ + + + E+EK L +LS L
Sbjct: 13942 QVENRKIMLDKQQKEVE--------DIMTVIKSERDVLEKEKSELNKLS------HVLNE 13987
Query: 763 QLTLAQEEISSTKEMLKDFIDN----MEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNI 596
++ QEE+ E +D I+N +E+ +++ +++ L + V E T+ +
Sbjct: 13988 KVQREQEELERLLEKERDDIENCKKIIESEKQSIERERAELKR--LKEEVEVQHERTL-L 14044
Query: 595 GFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQ 416
D++M + K+ E + E A T+ EE+ L+ +++ S + ML +
Sbjct: 14045 QQDKNMIQ------------KEKEHLEGEKARTT---EEIHNLKEEIKRKSSELDMLNK- 14088
Query: 415 NTKLELLAKKTSE 377
E+ AK+ E
Sbjct: 14089 ----EIEAKRQEE 14097
Score = 64.7 bits (156), Expect = 2e-07
Identities = 117/652 (17%), Positives = 266/652 (40%), Gaps = 26/652 (3%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L+ + D+QK K +E + L+ + QSE+ SL+ E++ + Q +
Sbjct: 14406 LNKAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIK--- 14462
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVL---KQELSSARLQIESLEKELNQANEEV 1892
E +Q ++ + + S+ + E + + ++ + + + E+E++ +
Sbjct: 14463 ----TEMQQIEIKMQIQTRSVATQWETDVQIQQEGQEPIETTGHITKKSEEEISAKKTKQ 14518
Query: 1891 KVLSKFRYQVL-ELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVE- 1718
+++K + E++E D++++ QL K++I E E+ E
Sbjct: 14519 PIVTKLEDTLTSEVQEMRDMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEET 14578
Query: 1717 ----ERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
R E +L +D++ N L++K E + +++QL ++ + K+
Sbjct: 14579 LKEKSRNEETLLQLLHDKDDLS-NTLDEKSKEIENITVTFKRNIAQLETTI----AMMKK 14633
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTM 1370
+ + N L++ E REI+ T T E E + V + L+ E
Sbjct: 14634 DKENIENELLQLKQTEQ-EREIQRGTDDTSNER----ENYDEKVTYKTELEDSKEKKKPD 14688
Query: 1369 DHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-ECKSKQMEE 1193
+L T S + ++ T + K + ++ L +E E K K + E
Sbjct: 14689 RDSSLKLTDADSAKTDGEREAQT--LETKVQDVLQLTDYTTQDQEELHDEMENKMKIILE 14746
Query: 1192 YKMLQAELNNWL-SCMNAEMGKFLCL------CNSMVYLEGDILKYKEDLLLNH-GQLRA 1037
+ +L C +AE K + + NS+ ++ ++L ++ ++H Q++
Sbjct: 14747 LNEAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQE--IDHLAQIKT 14804
Query: 1036 EMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICS 857
EM ++I++ + +V + W+ I +GQ E I
Sbjct: 14805 EMQQIEIKM----------QIQTRSVATQ---WETDVQIQQGQ------EATETTGHITK 14845
Query: 856 LSEKIQQIEEREKVLLTQL-STKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDT 680
SE+ ++ ++ +T+L T +++Q + L E+++ K ++K D +E + +
Sbjct: 14846 KSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVARMKTIMKMEKDQLEQAKS 14905
Query: 679 NLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAH 500
++Q+ + F+++M+EA+ E + ++++
Sbjct: 14906 DIQTQMEE---------------------FERNMEEAMEEKSRNEEKLLQLTHDKEDLSN 14944
Query: 499 TSDKDEEVIKLQSQ-----VENLQSLVQMLK--QQNTKLELLAKKTSEMDPE 365
T DK + I+ ++ + L++ + ++K ++N + ELL K +E + E
Sbjct: 14945 TLDKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQERE 14996
Score = 63.9 bits (154), Expect = 3e-07
Identities = 125/676 (18%), Positives = 275/676 (40%), Gaps = 49/676 (7%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDL-------KETVKNLQSDLDIEQKLSTDRQSEIYSL-SAELER 2087
++ + D+Q E+ +D+ + T + L +++I QK++ +Q+ + + + ER
Sbjct: 7007 IEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINI-QKVNQQKQATAFQMEKTDFER 7065
Query: 2086 ITQSEQMSLKRLKEAEQ----TLLEAESERESLKAELEESISVLKQELSSARLQIESLEK 1919
I + K L + ++ T+ E + ERE+L+ E+ +IS + +++ + S E
Sbjct: 7066 IKTEIDQANKELADQQEKNKKTITEMQKERETLE-EMRANISKQVETITNENKSLSSRES 7124
Query: 1918 ELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEV 1739
EL + E++ Q E++E + ++ QL ++++I LQ+
Sbjct: 7125 ELAKLQEDI------LQQQQEMDELKNTIMMEMC-----------QLDQRQSDIDLLQKE 7167
Query: 1738 I---------EQKEVEERQRECMLAASERSNDINVNALEK------KLSAYEGKIRRLEN 1604
+ E VE + E + +D+ +EK +L E K +E
Sbjct: 7168 VDDLMDFTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNEEK-DLIEK 7226
Query: 1603 DVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS 1424
+ LT ++D + + ++ N + I+N +E+ + K+++Q +EFS
Sbjct: 7227 ERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKELE-KMKISLQRKAIGFKEFSE 7285
Query: 1423 VVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXE 1244
K + ++ T D +G ++ Q+ + K E
Sbjct: 7286 KTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQT-----EKKRRKTYYTEDLFQE 7340
Query: 1243 CRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL 1064
+ +L+ K EE + E+ + +N E + S + +I K KE +
Sbjct: 7341 EKTDLQ------KTKEEINYDREEIYRQRTELNKEKETLKQMHTSNLKEIENIEKEKEKI 7394
Query: 1063 LLNHG---QLRAEMSSLKIELVEKNGFM----GYAVLDVENVQKELLIWKDRAMIAEGQS 905
Q+RAE+ + + ++ + M D+EN+Q E KD +
Sbjct: 7395 QRTWNELDQIRAELQNKQRDMDDTTNIMMKEKAELARDLENLQNE----KDELQKSRENI 7450
Query: 904 KAFQLELKHANMSIC-SLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISST 728
+ EL+ + +L+++ QQ E ++ K+ + + A++ + + +
Sbjct: 7451 QKLMKELQEERLKTSEALNKERQQFTE-------EIKLKNDSLDEIQAEIDRQKRALVTD 7503
Query: 727 KEML-KDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNI-----GFDQSMDEAV 566
KE++ K +D + D QS + I L + + +V I ++ DE +
Sbjct: 7504 KEIITKQMMDLQKTQDVRRQSDESDIARANLQRERESLDQLSVEILKQKQDLERERDELL 7563
Query: 565 SE---IAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQ-----VENLQSLVQMLKQQNT 410
+ + Q N++ + + TE+ + E++ K Q EN +L + L++ N
Sbjct: 7564 EQWRLVETQKMDNENVKQLKTELLDEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNL 7623
Query: 409 KLELLAKKTSEMDPEK 362
+ + + + ++++ K
Sbjct: 7624 QKQGIQDERAQLERMK 7639
Score = 63.9 bits (154), Expect = 3e-07
Identities = 130/706 (18%), Positives = 276/706 (39%), Gaps = 79/706 (11%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLD--------IEQKLSTDR------------- 2126
++ +R DI +EKN ++ +SDL+ +Q + +R
Sbjct: 12693 IEKIRQDIDREKN-------DLEKYRSDLEKQYEEMEICKQNIENERAELEIDLENIIIE 12745
Query: 2125 ----QSEIYSLSAELE---------------RITQSEQMSLKRLKEAEQTLLEAESERES 2003
Q + S+ +L+ R + + + K +E EQ E E++
Sbjct: 12746 TKSKQERLESIEVQLQEKNVQMGTILDELNKRQEELDAIKAKTQREKEQMGHTEELEKDE 12805
Query: 2002 LKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSAD 1823
L A L++ ++K+ + + Q E L+KE +Q L K + LE+E + L+++
Sbjct: 12806 LIAILQKREEIVKRHMEEIQNQREELQKEKDQFGNMQAELQKGQ---LEMEMHQLMLNSE 12862
Query: 1822 ----------LSKVHEDYSAALRQLFDKKNEITCLQEVI-EQKEVEERQRECMLAASERS 1676
L K E++ + L ++ E + L++++ E+K VEE M A +
Sbjct: 12863 RDELNGMRVNLEKQKEEFELMQQNLESRRPE-SLLEDILKEKKRVEE-----MAAQLSKE 12916
Query: 1675 NDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDL----LQE 1508
+ N + + + E KI+++E ++ + + + ++E + N + LQ
Sbjct: 12917 QEEFRNIMSETIKRME-KIKQIEGEIKTKQIEMACLEELKQKELDEQKNMRECENQELQM 12975
Query: 1507 IENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSN------TMDHDTLSST 1346
L +++ E + E + +++ LE +K L+ + HD +
Sbjct: 12976 RREELAKMKTEIDIERDEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQHDEIHGG 13035
Query: 1345 HQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELN 1166
E++ + D K + LE +E + +QM ++ E N
Sbjct: 13036 IDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQM----AVETEDN 13091
Query: 1165 NWLSCMNAEMGKFLCLC-------NSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELV 1007
+ + EM K + N + + ++ + K +L N L E + L ++
Sbjct: 13092 DSDKNLQDEMMKIEAILKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNKKVK 13151
Query: 1006 EKNGFMGYAVLDVENVQKELLIWKDRAM--IAEGQSKAFQLELKHANMSICSLSEKIQQI 833
E F + + E +K + +R M +AE K +K + ++ E+I++
Sbjct: 13152 ETEEFHMSKMEEREAERKTI----ERVMDEMAEEHEK-----IKKEREELVNMEEEIKKQ 13202
Query: 832 EEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQ-SHFNQ 656
+ + +++ K +++QH + E+ K+ L+D I + D + + S ++
Sbjct: 13203 RRVLEESMNEMTKKKSELQH-------ERSELYKQKQQLEDMIASESKRDVDTERSRQDK 13255
Query: 655 IQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEV 476
E +L + E ++++ Q K+ ED+ T + + E +
Sbjct: 13256 EDEQILKRE-----------------REEIADMKDQLL--KEKEDVETTKERINREKEHI 13296
Query: 475 IKLQSQVENL--------QSLVQMLKQQNTKLELLAKKTSEMDPEK 362
K+QSQ+ + Q L+ M + K L K ++ E+
Sbjct: 13297 EKMQSQLNDQKEEMDLENQKLLYMKTEIQVKTNALEKMMQDLQKER 13342
Score = 63.5 bits (153), Expect = 4e-07
Identities = 110/654 (16%), Positives = 277/654 (42%), Gaps = 44/654 (6%)
Frame = -2
Query: 2230 RLDIQKEKNISEDL-------KETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSE 2072
+ DI+ K I + L K ++ + +LDIE++ D Q + +EL+ +
Sbjct: 10665 KCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERI 10724
Query: 2071 QMSLKRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKEL-NQA 1904
+ + +K+ +TL E E+ E K E++ E LK++L + K+L NQ
Sbjct: 10725 RNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRLKEDLEKMSTDVNKQNKDLMNQR 10784
Query: 1903 N----EEVKVLSKFRYQVLELEEYSQQLS----ADLSKVHEDYSAALRQLFDKKNEITCL 1748
+ E ++ K++ ++E+ Q+S DL K + + L + K + +
Sbjct: 10785 DLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPK-EKGMKEDRKSLEETKANVIEM 10843
Query: 1747 QEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFS 1568
+ E +E+++ + + E +I V ++ Y+ +++++ ++ +D
Sbjct: 10844 KTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELYQ-----IKSELERVRSEID-- 10896
Query: 1567 AGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQL 1388
E K+++ ++++ + L +++ E Q+ E + ++ K +
Sbjct: 10897 -----HEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDI 10951
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKS 1208
E S + + E + Q + D + + + L+NE +
Sbjct: 10952 EKSKEIVEKLMVEVE----EQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERI 11007
Query: 1207 KQM-EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEM 1031
K++ EE K + L + E + + + D+ K D+ L+ +
Sbjct: 11008 KKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQR 11067
Query: 1030 SSLKIELVEKNGFMGYAVLDVE------NVQKELL----IWKDRAMIAEGQSKAFQLELK 881
L+ E E N M ++ + Q+E L + ++R + E +++ +++ K
Sbjct: 11068 DLLEQEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTK 11127
Query: 880 HANMSICSLSEKIQQIEEREKVLL----TQLSTKDTDMQHLAAQLTLAQEEISSTKEMLK 713
I + EK ++ EE +V++ +L+ ++++ + +++ Q++++ K++++
Sbjct: 11128 AELQEI--MQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIE 11185
Query: 712 DFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFD-QSMDEAVSEIAVQTFPN 536
+++E + + + Q++E ++ ++ T D ++ E V ++ V+
Sbjct: 11186 QEKEDLEKMKSEIMTQRQQMEEE--RSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQ 11243
Query: 535 K-----DTEDINTEIAHTSDKDEEVI----KLQSQVENLQSLVQMLKQQNTKLE 401
+ E+++ E +D+ V+ KLQ++ E ++ + + +K++ L+
Sbjct: 11244 RKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLK 11297
>ref|XP_005159739.1| PREDICTED: titin isoform X2 [Danio rerio]
Length = 15734
Score = 105 bits (261), Expect = 1e-19
Identities = 135/637 (21%), Positives = 287/637 (45%), Gaps = 30/637 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD + ++ K++ D+ ET+KN + LD +++ +++ EI + ++ S
Sbjct: 3781 LDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDED 3840
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEE---SISVLKQELSSARLQIESLEKELNQANEEV 1892
LK +K +Q E +++ E +K ELE I +K+E+ + R +E + +EL + E
Sbjct: 3841 LKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESF 3900
Query: 1891 KVL---SKFRYQVL-ELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKE 1724
L +K ++L E++ ++ L A+L K ++ + + ++ +E + +E
Sbjct: 3901 THLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLRE 3960
Query: 1723 VEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEES 1544
E Q + + +R + + +E + +A I ++ D+ +S+D A K +
Sbjct: 3961 DELGQLQAEIHKQQREIEKEKSNIESERAA----IIKIVEDLQHKIISLDRDAESLKLDR 4016
Query: 1543 TKVSNACDLLQ----EIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQLETS 1379
N ++L+ E+E EI + K+ Q R VEE ++ + K + + + +E +
Sbjct: 4017 EAFENEREVLKQMKTELERETDEIE-KIKLETQHDRQRVEEMTAQITKERDKINNLIEET 4075
Query: 1378 NTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE------- 1220
N D L+ ++ E S QS + + + +++LE +
Sbjct: 4076 NRKDM-VLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQKENTLAE 4134
Query: 1219 -----ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLN 1055
E K E + E+ + M + + L + L+ ++ K KE ++ +
Sbjct: 4135 IQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKD 4194
Query: 1054 HGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHA 875
R+E+ + EL ++ M + ++N +K L+ KD+ + E Q + + E +
Sbjct: 4195 ----RSELDLRQSELDKQQTNMNDIIETMKNERK--LLDKDKEEMEE-QKQEMEKERDNM 4247
Query: 874 NMSICSLSEKIQQIEEREKVL---LTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFI 704
+ SI SL E ++ ++ +++V+ +L ++Q A ++ +EE + ++ L+
Sbjct: 4248 DQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQNERQSLEKMT 4307
Query: 703 DNM--EASD-TNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNK 533
+ E D +L + + +EML V A + D ++ + E + +K
Sbjct: 4308 KALIKEREDLVHLAEYTKREKEMLDEMQV-----ANKSSMADLQREKRILEEMRENI-SK 4361
Query: 532 DTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
TEDI E + +++E+ KLQ++V+ QS + M K
Sbjct: 4362 QTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEK 4398
Score = 102 bits (253), Expect = 9e-19
Identities = 127/657 (19%), Positives = 292/657 (44%), Gaps = 30/657 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD + ++ K++ D+ ET+KN + LD +++ +++ E+ +++ +S
Sbjct: 6348 LDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDED 6407
Query: 2062 LKRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQANEEV 1892
LK +K +Q + E +++ E +K ELE + I +K+E + R +E + +EL + ++V
Sbjct: 6408 LKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDV 6467
Query: 1891 KVLS----KFRYQVLELEEYSQQLSADLSK-------VHEDYSAALRQLFDKKNEITCLQ 1745
L+ + + + E++ ++ ADL K + E+ S + +K++I +
Sbjct: 6468 AHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLRE 6527
Query: 1744 EVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSA 1565
+ +EQ + E +++ + + + A+ K + + KI L+ D L L +
Sbjct: 6528 DELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDRE--- 6584
Query: 1564 GVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQL 1388
F+ E ++ L+ + + +I++ET Q R VEE ++ ++ + + QL
Sbjct: 6585 -AFENEKEELKQMKTELEREADEIEKIKLET----QHERQRVEEMTADFMETMNNERKQL 6639
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKS 1208
+ + M E K + D D +Q LE E+ K
Sbjct: 6640 DKNKVMIE-----------EQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKL 6688
Query: 1207 KQM--------EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL---- 1064
+QM +E ++ E N + L YL +I + + L
Sbjct: 6689 EQMKIGLEREADEISKIKEETQNERQNLEKMAN---ALKEEREYLAEEIKRKNQVLDKIK 6745
Query: 1063 LLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKD--RAMIAEGQSKAFQL 890
+ N L A++ K L E + + D+EN +++ + +D + + E Q + ++
Sbjct: 6746 VANESTL-ADLQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEI 6804
Query: 889 ELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKD 710
+++ N+ SE+ I E++ ++T+L K D++ ++ +E + + + +LK
Sbjct: 6805 DMEKTNIE----SERAAMIREKQN-MMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKK 6859
Query: 709 FIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKD 530
+++++ +++ ++++ EA N ++M + +++ +Q +
Sbjct: 6860 DVEDLQQKLMSIERD---------SESLKLDKEAFEN--EKEAMKQMKTDLQIQA---DE 6905
Query: 529 TEDINTEIAHTSDK-DEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEK 362
E I E H + +E+ ++Q + E + +LV+ +K+ K +++ + +E+ EK
Sbjct: 6906 IEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIKK---KRDIIDESYTEIRKEK 6959
Score = 100 bits (250), Expect = 2e-18
Identities = 128/638 (20%), Positives = 274/638 (42%), Gaps = 31/638 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD + ++ K++ D+ ET+KN + LD +++ + +++ E+ + ++ +S
Sbjct: 5061 LDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 5120
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEE---SISVLKQELSSARLQIESLEKELNQANEEV 1892
LK +K +Q L + +S+ E +K ELE I +K+E+ + R +E + + L + E++
Sbjct: 5121 LKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL 5180
Query: 1891 KVLSKFRYQVL-ELEEYSQQLSAD-------LSKVHEDYSAALRQLFDKKNEITCLQEVI 1736
+K QVL E++ ++ AD L ++ E+ S + +KK + ++ +
Sbjct: 5181 AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDEL 5240
Query: 1735 EQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTL---SVDFSA 1565
Q + E +++ + + + + A+ K + + KI L+ D L L + +
Sbjct: 5241 RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEK 5300
Query: 1564 GVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQL 1388
V K+ T++ D +++I K+ Q R VEE ++ + K + + + +
Sbjct: 5301 EVLKQMKTELEREADEIEKI-----------KLETQHDRQRVEEMAAQIQKDRDEINNLI 5349
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE---- 1220
E +N D L+ ++ E S QS + + + +++LE +
Sbjct: 5350 EETNRKDM-VLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENT 5408
Query: 1219 --------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL 1064
E K E E+ + MN + + L + L+ ++ K KE +
Sbjct: 5409 LAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEII 5468
Query: 1063 LLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLEL 884
+ + QL S L + N M ++N +K+L KD+ + E Q + + E
Sbjct: 5469 MKDRSQLDLRQSELDKQQTNMNDIME----TMKNERKQL--DKDKEEMEE-QKQEMEKER 5521
Query: 883 KHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFI 704
+ + S SL E +++ K+ + ++ + +L +EIS KE ++
Sbjct: 5522 DNMDQSRKSLDED----QKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKR 5577
Query: 703 DNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAV----QTFPN 536
+E L + + + + + + + SM + E ++ + +
Sbjct: 5578 QRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENIS 5637
Query: 535 KDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
K E I+ E + +++E+ KLQ++V+ QS + M K
Sbjct: 5638 KLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEK 5675
Score = 95.1 bits (235), Expect = 1e-16
Identities = 127/646 (19%), Positives = 274/646 (42%), Gaps = 26/646 (4%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
D+Q+EK+I E+++E + L+ +D E++ S R+ E+ L E++ K+ +
Sbjct: 5621 DLQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQ----------KQQSK 5670
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSK---- 1877
+ ESER ++ E + ++ LK++ +Q++ + E + + K+L++
Sbjct: 5671 IDMEKTNIESERAAMIREKQNMMTELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVEN 5730
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVE---ERQR 1706
+ ++++LE S++L D + E+ A++Q+ K ++ + IE+ ++E +RQR
Sbjct: 5731 LQQKLIDLERDSKRLKLD-REAFENEKEAMKQM---KTDLQIQADEIEKIKLETQHDRQR 5786
Query: 1705 ECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNA 1526
+AA + +N L ++ + + + D+ + S+ + ++E +
Sbjct: 5787 VEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKT 5846
Query: 1525 CDLLQEIENFLREIRVETKVTIQEARHNVEEFS-SVVKHLEYLKSQLETSNTMDHDTLSS 1349
L +++ L + + T IQ+ R +VE+ + ++ + + +K Q E N
Sbjct: 5847 RSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMN--------- 5897
Query: 1348 THQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-ECKSKQMEEYKMLQAE 1172
+D+ + N +Q LE E E K ++ + Q+E
Sbjct: 5898 ----QKQDELDQLKTEIQN----------------LQQELEKEKEIIMKDRSQFDLRQSE 5937
Query: 1171 L-------NNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIE 1013
L N+ + M E + M + ++ K K D + L ++ +K++
Sbjct: 5938 LDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKDLKMMKLQ 5997
Query: 1012 ---LVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSE-- 848
E+ + +++E E+ K+ + ELK S L+E
Sbjct: 5998 KQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFTHLAEDT 6057
Query: 847 -KIQQIEEREKV----LLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASD 683
K Q+I ++ KV L+ L + ++++ + ++ E++ + KE L+ D +
Sbjct: 6058 KKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLREDEL---- 6113
Query: 682 TNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIA 503
LQ+ + Q + + +N E I K+ ED+ +I
Sbjct: 6114 WQLQAEIYKQQREIEKEKINIESERAAII--------------------KNVEDLQHKII 6153
Query: 502 HTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPE 365
+ D+D E +KL E ++ ++LKQ T+LE A + ++ E
Sbjct: 6154 -SLDRDSESLKLDR--EAFENEREVLKQMKTELEREADEIEKIKLE 6196
Score = 92.0 bits (227), Expect = 1e-15
Identities = 137/648 (21%), Positives = 278/648 (42%), Gaps = 30/648 (4%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIE-QKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++ +K+I E+ + + DL E K S D + ++ + E E + ++ K ++
Sbjct: 3594 EMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLTEKELLESDRKLLKKDVE 3653
Query: 2047 EAEQTLLEAESERESLKAE---LEESISVLKQELSSARLQIESLEKELNQANEEVKVLSK 1877
+Q LL ES+ ESLK + LE VLKQ + + + E +EK + E + + +
Sbjct: 3654 NLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEE 3713
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIE--QKEVEERQRE 1703
Q+ + EY Q+++ ++++ D +Q+ K++E+ L+ I+ Q+E+E+ +
Sbjct: 3714 MTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQELEKEKEI 3773
Query: 1702 CMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSV---------------DFS 1568
M SE D+ + L+K+ + I ++N+ QL DF
Sbjct: 3774 IMKDRSEL--DLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFD 3831
Query: 1567 AG--VFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKS 1394
G E+ + + +E +N L ++++E + E R EE + + LE +
Sbjct: 3832 QGRNSLDEDLKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTE 3891
Query: 1393 QLETSNTMDHDTLSSTHQGSMEDKASSQSSTGD----NDPKAXXXXXXXXXXXECRQNL- 1229
+L+ + S TH ED Q + N+ E R+N+
Sbjct: 3892 ELK------REKESFTHLA--EDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENIS 3943
Query: 1228 -ENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNH 1052
+ E+ K+K+ E ++ + EL + ++ + + +++ I+K EDL
Sbjct: 3944 KQTEDVKNKK-ENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKI 4002
Query: 1051 GQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHAN 872
L + SLK+ ++ F EN ++ L K + + +LE +H
Sbjct: 4003 ISLDRDAESLKL---DREAF--------ENEREVLKQMKTELERETDEIEKIKLETQHDR 4051
Query: 871 MSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNME 692
+ ++ +I + ++ L+ + + KD + + + I S K+ML+ N+E
Sbjct: 4052 QRVEEMTAQITKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLE 4111
Query: 691 ASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINT 512
+ +S +++E L Q N E Q E + K E+I
Sbjct: 4112 KT----RSELYKVKEDLEKQKENTLAEI-------QKEREDL---------EKMNENITI 4151
Query: 511 EIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTK-LELLAKKTSEMD 371
E+ ++E++ + Q +++ L++ +Q L+Q+ K E++ K SE+D
Sbjct: 4152 EMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELD 4199
Score = 92.0 bits (227), Expect = 1e-15
Identities = 127/649 (19%), Positives = 278/649 (42%), Gaps = 43/649 (6%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSL 2060
D + ++ K++ D+ ET+KN + LD +++ +++ E+ + ++ +S L
Sbjct: 5932 DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKDL 5991
Query: 2059 KRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQANE--- 1898
K +K +Q E +++ E +K ELE + I +K+E + R +E + +EL + E
Sbjct: 5992 KMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFT 6051
Query: 1897 --------EVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQE 1742
E ++L K + L Q+ ++L ++ E+ S + +KK + ++
Sbjct: 6052 HLAEDTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLRED 6111
Query: 1741 VIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTL---SVDF 1571
+ Q + E +++ + + + + A+ K + + KI L+ D L L + +
Sbjct: 6112 ELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFEN 6171
Query: 1570 SAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKS 1394
V K+ T++ D +++I K+ Q R VEE ++ + K + + +
Sbjct: 6172 EREVLKQMKTELEREADEIEKI-----------KLETQHDRQRVEEMTAQIQKDRDKINN 6220
Query: 1393 QLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-- 1220
+E +N D L+ ++ + S QS + + + +++LE +
Sbjct: 6221 LIEETNRKDM-VLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKE 6279
Query: 1219 ----------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKE 1070
E K E E+ + MN + + L + L+ ++ K KE
Sbjct: 6280 NTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKE 6339
Query: 1069 DLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQL 890
++ QL S L + N M ++N +K+L KD+ + E Q + +
Sbjct: 6340 IIMKARSQLDRRQSELDKQQTNMNDIME----TMKNERKQL--DKDKEEMEE-QKQEMEK 6392
Query: 889 ELKHANMSICSLSEKIQQIEEREKVL---LTQLSTKDTDMQHLAAQLTLAQEEISSTKEM 719
E + + S SL E ++ ++ +++V+ +L +++ A + +EE + +++
Sbjct: 6393 ERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQI 6452
Query: 718 LKDFIDNME---------ASDTNLQSHFNQIQEM-LLNQNVNYPLEATVNIGFDQSMDEA 569
L+ + ++ A DT + N + EM + N++ L+ +++E
Sbjct: 6453 LEKMAEELKKERKDVAHLAEDTKREK--NSLDEMKVANESSMADLQKE-----KSNLEEM 6505
Query: 568 VSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
I +K TEDI E +++E+ +LQ+++ QS ++ K
Sbjct: 6506 KENI------SKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEK 6548
Score = 84.0 bits (206), Expect = 3e-13
Identities = 120/635 (18%), Positives = 266/635 (41%), Gaps = 27/635 (4%)
Frame = -2
Query: 2245 TLDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQM 2066
T+ R + K+K +E+ K+ ++ + D D +K S
Sbjct: 4667 TMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRK---------------------SLDE 4705
Query: 2065 SLKRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQANEE 1895
LK +K +Q + E +S+ + +K ELE + I +K+E + R E + + L + E+
Sbjct: 4706 DLKMMKLQKQVIEEEKSKLKQMKIELEREADEIRKVKEETQNERQIFEKMTEALKKERED 4765
Query: 1894 VKVLSKFRYQVL-ELEEYSQQLSAD-------LSKVHEDYSAALRQLFDKKNEITCLQEV 1739
+ +K + QVL E++ ++ AD L ++ E+ S + +KK +I +E
Sbjct: 4766 LSEDAKRKNQVLDEMKVANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLREEK 4825
Query: 1738 IEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGV 1559
++Q + E +++ + + + A+ K + + KI L+ D L L +
Sbjct: 4826 LKQLQAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDRE----A 4881
Query: 1558 FKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQLET 1382
F+ E ++ L+ + + +I++ET Q R VEE ++ + K + + + +E
Sbjct: 4882 FENEKEELKQMKTELEREADEIEKIKLET----QHDRQRVEEMTAQIQKERDKINNLIEE 4937
Query: 1381 SNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE------ 1220
+N D L+ E + +S + + ++NLE +
Sbjct: 4938 TNRKDM-VLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKLA 4996
Query: 1219 ------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLL 1058
E K E++ + ++ + M + + L + L+ ++ K KE ++
Sbjct: 4997 EIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMK 5056
Query: 1057 NHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKH 878
+ QL S L + N M ++N +K+L K+ E Q + + E
Sbjct: 5057 DRSQLDLRQSELDKQQTNVNDIME----TMKNERKQLDKDKEE---TEEQKQEMEKEKHD 5109
Query: 877 ANMSICSLSEKIQQIEEREKVL---LTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDF 707
+ S SL E ++ ++ +++VL ++L +++ A ++ +EEI + ++ L+
Sbjct: 5110 FDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKM 5169
Query: 706 IDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDT 527
+ ++ +L + ++L V + +++E I +K T
Sbjct: 5170 TEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENI------SKQT 5223
Query: 526 EDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
ED+ + + +++E+ +LQ+++ Q ++ K
Sbjct: 5224 EDVENKKENLRLREDELRQLQAEIHKQQREIEKEK 5258
Score = 84.0 bits (206), Expect = 3e-13
Identities = 137/676 (20%), Positives = 281/676 (41%), Gaps = 48/676 (7%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDL-DIEQKLSTDRQSEIYSLS-AELER---ITQ 2078
L R DI+K E K ++ + +L D + +L DR + ++ EL+R + +
Sbjct: 9202 LQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRE 9261
Query: 2077 SEQMSLKRLKEAEQTLL---EAESERESLK-------------AELEESISVLKQELSSA 1946
+E + K L++ EQ + + E++ E+L+ A+ E++ +Q+L
Sbjct: 9262 TEDLERKILQQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLL 9321
Query: 1945 RLQIESLEKELNQA--NEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFD 1772
+ ++S E EL EE K L + + + E + ++S ++ +Y + +L
Sbjct: 9322 QGALQSQESELENRVFMEEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQR 9381
Query: 1771 KKNEITCLQEVIEQKEVE--------ERQRECMLAASERSNDINVNALEKKLSA---YEG 1625
+K ++ + IEQ++ + ERQ E + D NALEK S +
Sbjct: 9382 EKEQLEISKNQIEQEKKDLQNMKSNLERQLESLRHEKANVED-EKNALEKMRSESKEIQN 9440
Query: 1624 KIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARH 1445
IR+ D+ + ++ +EE+ ++ + ++++++ L++ R + ++ +
Sbjct: 9441 AIRKEREDLENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINN 9500
Query: 1444 NVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXX 1265
+EE + + K ++E + D E + D K
Sbjct: 9501 KMEELLQMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQE--- 9557
Query: 1264 XXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDI 1085
+ E K + +E K L E+ + + EM + +G +
Sbjct: 9558 ------------KEREIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLL 9605
Query: 1084 LKYKEDLLLNHGQLRAEMSSL---KIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAE 914
K K++L +L +M L K E E+ + +E+++KE I K++ + +
Sbjct: 9606 EKEKQELKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEK 9665
Query: 913 GQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTK-DTDMQHLAAQLTLAQEE- 740
+ QL++ L+++ ++ ++EK L Q + + Q L T EE
Sbjct: 9666 SNIEEMQLKIFKQQR----LNDQTREENKKEKESLEQQRFETEQQKQMLEISTTKMMEEK 9721
Query: 739 -----ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMD 575
+S + KD ++ + A TN + H + + L+ + +E I D+
Sbjct: 9722 NEMADLSRELQKAKDELEKI-AYKTNKERHEVEQMQAELHSQIQ-AIEQQGQIMQDKQNH 9779
Query: 574 EAVSEIAVQTFPNK---DTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTK- 407
E+++Q + + E H ++ EE K Q +E +++ +++ KQ+N K
Sbjct: 9780 LEEKELSIQRKEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQKNNKD 9839
Query: 406 LELLAKKTSEMDPEKY 359
ELL K SE++ EKY
Sbjct: 9840 FELLEKIRSELENEKY 9855
Score = 80.1 bits (196), Expect = 4e-12
Identities = 118/630 (18%), Positives = 261/630 (41%), Gaps = 10/630 (1%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
D+Q+EK I E+++E + D++ E++ S R+ E+ L E++ K+ E
Sbjct: 4344 DLQREKRILEEMRENISKQTEDIENEKEKSKLREDELKKLQTEVQ----------KQQSE 4393
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESL--EKEL--NQANEEVKVLSK 1877
+ ESER + E + ++ LK++ +Q++ + EKEL N +N K +
Sbjct: 4394 IDMEKTNIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMED 4453
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVE---ERQR 1706
+ +++ +E S+ L D E + L K ++ + IE+ ++E +RQR
Sbjct: 4454 LKQKLMSIERDSESLKLD----REAFGNEKEVLKQMKTDLQIQADEIEKIKLETQHDRQR 4509
Query: 1705 ECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNA 1526
A + + +N L + + + + ++ D+ + S+ + ++E +
Sbjct: 4510 VEEKTAQIQKDRDEINNLIVETNRKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLEKT 4569
Query: 1525 -CDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSS 1349
+L + EN + +E K I++ + N+ +KH E Q + + +
Sbjct: 4570 RSELARAKENLETQREIERK-DIEKMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQN 4628
Query: 1348 THQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAEL 1169
Q ++K + D + + + ++NE KQ+++ K E
Sbjct: 4629 LQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNER---KQLDKDK---EET 4682
Query: 1168 NNWLSCMNAEMGKFLCLCNSMVYLEGDI--LKYKEDLLLNHGQLRAEMSSLKIELVEKNG 995
M E F S L+ D+ +K ++ ++ + ++++ +KIEL +
Sbjct: 4683 EEQKQEMEKEKHDF---DQSRKSLDEDLKMMKLQKQVI---EEEKSKLKQMKIELEREAD 4736
Query: 994 FMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKV 815
++ V++E ++ I E ++A + E + + ++ + +++ +
Sbjct: 4737 -------EIRKVKEET---QNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANES 4786
Query: 814 LLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLN 635
L + + +++Q + ++ E++ + KE ++ E LQ+ ++ Q
Sbjct: 4787 TLADILRERSNLQEMRENISKQTEDVENKKEKIR----LREEKLKQLQAEIHKQQSETEK 4842
Query: 634 QNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQV 455
+ N E I KD ED+ ++I + D+D E +KL
Sbjct: 4843 EKSNIERERAAII--------------------KDVEDLQSKII-SLDRDAESLKLDR-- 4879
Query: 454 ENLQSLVQMLKQQNTKLELLAKKTSEMDPE 365
E ++ + LKQ T+LE A + ++ E
Sbjct: 4880 EAFENEKEELKQMKTELEREADEIEKIKLE 4909
Score = 79.7 bits (195), Expect = 5e-12
Identities = 122/685 (17%), Positives = 295/685 (43%), Gaps = 64/685 (9%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
+I+KEK KE + + + +I + T+R+ E+Y + +ELER+ K+L +
Sbjct: 10995 EIKKEKE-----KENEEEEEEEEEIRVIVETERK-ELYQIKSELERVRSEIDHEQKKLND 11048
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSA--RLQIESLEKELNQANEEV--KVLSK 1877
+ + + + + E +K+E+ + +++E S ++Q +LEK + ++E+ K++ +
Sbjct: 11049 YMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVE 11108
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECM 1697
Q +++ ++L + K+ ++ + ++ +NE +++V E+ +++RE +
Sbjct: 11109 VEEQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKKVDEE---IKKERETL 11165
Query: 1696 LAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDL 1517
R +I++ +++L + + +R + D+ +++ ++ E+ + N DL
Sbjct: 11166 -----REMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDIN-------EQKLHLKNQRDL 11213
Query: 1516 LQEIENFLREIRVETKVTIQEARHNVEEFSSVV--KHLEYLKSQLETSNTMDHDTLSSTH 1343
L+ + R E + + + ++EF + V + + K ++E +T +
Sbjct: 11214 LE-------QEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARII 11266
Query: 1342 QGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECK---SKQMEEYKMLQAE 1172
+ M+ KA Q + + + + EE + + EE +++E
Sbjct: 11267 E--MKTKAELQEIMQEKEEE------------------DEEEMRVIVEMEREELNQIKSE 11306
Query: 1171 LNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSL---------- 1022
L S ++ E K + + D+ K K +++ Q+ E S L
Sbjct: 11307 LKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLE 11366
Query: 1021 KIELVEKNGFMGYAVLDVENVQKELLIWK-----DRAMIAEGQSKAFQ--LELKHANMSI 863
+ ++ + ++ VE +K++ + K +R IA+ Q Q +L++ N I
Sbjct: 11367 RHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERI 11426
Query: 862 CSLSEKI---------------QQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISST 728
+ E+I ++ EE V+ K D++ ++ + +++ +
Sbjct: 11427 KEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDVNKQNQDLMNQ 11486
Query: 727 KEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEA---VSEI 557
+++LK + + T LQ ++ + Q + +S++E + E+
Sbjct: 11487 RDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEM 11546
Query: 556 AVQTFP-----NKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLV-----------QML 425
+T P K+ E+ A K EE+ +++SQ+E ++S + +M+
Sbjct: 11547 KTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMI 11606
Query: 424 KQQNTKLEL----LAKKTSEMDPEK 362
+Q+ LE + K+ +M+ E+
Sbjct: 11607 EQEKEDLEKMKSEIMKQRQQMEEER 11631
Score = 78.6 bits (192), Expect = 1e-11
Identities = 129/680 (18%), Positives = 300/680 (44%), Gaps = 61/680 (8%)
Frame = -2
Query: 2227 LDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++IQKE+ I E LK + + DL+ E+ +++I SLS +L+ ++ E + R +
Sbjct: 3114 VEIQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI-SLSEDLKEQSEREGIDNTRTR 3172
Query: 2047 ----------------------EAEQTLLEAESER-ESLKAELEESISVLKQELSSARLQ 1937
E ++ ++E E ++ E +KAEL++ K EL + R
Sbjct: 3173 IKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNERQN 3232
Query: 1936 IESLEKELNQANEEVKVLSK--FRYQV----LELEEYSQQLSADLSKVHEDYSAALRQLF 1775
+E +L + E V+ L++ R QV +++E Q+ + + +K ++ L +L
Sbjct: 3233 LEEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQE--RVLIELK 3290
Query: 1774 DKKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVS 1595
+I +E +E + +EER++ + A ++ + L++ +S + I N
Sbjct: 3291 KTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDI---VNKTE 3347
Query: 1594 QLTLS----VDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFS 1427
QL L A +++++ +N ++ E + L + E +E +E S
Sbjct: 3348 QLRLREVELEQLQALIYRQQDEIEANRKAIINE-KYRLEGQKTEIDRLQREVNQMMEYAS 3406
Query: 1426 SVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSS-TGDNDPKAXXXXXXXXXX 1250
+LE KS++ + D + +G +E++ ++ + D K
Sbjct: 3407 KDRANLEKEKSEM-IAQKHQMDIELNKERGLIEERTQMLNTYEKEMDQKRTALEVEMKEL 3465
Query: 1249 XECRQNLENEECKSKQM--------EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLE 1094
+Q ++ E+ K +QM ++ K L+ + N + + + +L
Sbjct: 3466 KYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLAHLA 3525
Query: 1093 GDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAE 914
D + +++ + H A++ K L + M +++ +K++++ +D+ +
Sbjct: 3526 EDTKRKDDEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQQMQ 3585
Query: 913 GQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEIS 734
+ Q E+ SI + + + ++ + L+T+L+ + D++ ++ +E +
Sbjct: 3586 AEINRQQTEM-DTKKSI--IENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLTEKELLE 3642
Query: 733 STKEMLKDFIDNMEASDTNLQS---HFNQIQEMLLNQ---------NVNYPLEATVNIGF 590
S +++LK ++N++ ++S Q +E+L N+ ++ E I
Sbjct: 3643 SDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKL 3702
Query: 589 D-----QSMDEAVSEIAV-QTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQM 428
+ Q ++E ++I + + K ++I EI +++++ + Q +++ L++ +Q
Sbjct: 3703 ETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQN 3762
Query: 427 LKQQNTK-LELLAKKTSEMD 371
L+Q+ K E++ K SE+D
Sbjct: 3763 LQQELEKEKEIIMKDRSELD 3782
Score = 76.3 bits (186), Expect = 5e-11
Identities = 150/706 (21%), Positives = 304/706 (43%), Gaps = 71/706 (10%)
Frame = -2
Query: 2233 VRLDIQKEKNISEDLKET-------VKNLQSDLDIEQKLSTD--------------RQSE 2117
+++++QK+KN E+L+ T V+N + LD +QK D +SE
Sbjct: 14062 LQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSE 14121
Query: 2116 IYSLSAELERITQSEQMSLKRLKEAEQTLLE-----AESERESLKAE------LEESISV 1970
+ LS L Q EQ L+RL E E+ +E ESE++S++ E L+E + V
Sbjct: 14122 LNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIESEKQSIERERAELKRLKEEVEV 14181
Query: 1969 ------LKQELSSARLQIESLEKELNQANEEVKVL-SKFRYQVLELEEYSQQLSADLSKV 1811
L+Q+ + + + E LE E + EE+ L + + + EL+ ++++ A K
Sbjct: 14182 QHERTLLQQDKNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEA---KR 14238
Query: 1810 HEDYSAALRQLFD----KKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKK 1643
E+ L + + K E L+E I +K+ + ++ L + R + +L++
Sbjct: 14239 QEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQ-TSLDEI 14297
Query: 1642 LSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREI-RVET-- 1472
E + R LE V+ + V K E T S ++ + N ++E+ R++T
Sbjct: 14298 TKTDERRQRALEETVA----TTAKQPIVIKLEDTLTSEVQEMRDHLNNEIKELARMKTIM 14353
Query: 1471 ---KVTIQEARHNV----EEFSSVVKHLEYLKSQLE---TSNTMDHDTLSSTHQGSMEDK 1322
K +++A+ ++ EEF ++ KS+ E T D + LS+T +
Sbjct: 14354 KMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLD---KKN 14410
Query: 1321 ASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNA 1142
+++T K + ++N+ENE + KQ+E+ + +Q + + ++
Sbjct: 14411 KEIENNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQIEQEREIQRKAD--VTSTEK 14468
Query: 1141 EMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVE- 965
EM Y E + YK +L + +++ + S +EL + + + +
Sbjct: 14469 EM-----------YTEK--VTYKTELEDSKEKIKPDRDS-TLELTDTDSAKTDGEREAQT 14514
Query: 964 ---NVQKELLIWKDRAMIAEGQSKAFQ------LELKHANMSICSLSEKIQQIEEREKVL 812
VQ L + D E + LEL A + L E+ + EE + V+
Sbjct: 14515 LETKVQDVLQLTDDTTQDQEELHDEMENKMKIILELNKAKKDLQKLKEECRSAEEEKSVI 14574
Query: 811 LTQLSTKDTDMQHLAAQ-LTLAQE--EISSTKEMLKDFIDNMEASDTNLQSHFNQIQEML 641
+ L + ++ + ++ L+L QE ++ K ++ M+ ++ + + ++
Sbjct: 14575 MESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWE--TDVQ 14632
Query: 640 LNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKD-EEVIKLQ 464
+ Q P+E T +I +S +E ++ Q K + + +E+ D + E+V +++
Sbjct: 14633 IQQEGQEPIETTGHI-TKKSEEEISAKKTKQPIVTKLEDTLTSEVQEMRDMEIEDVARMK 14691
Query: 463 SQVENLQSLVQMLKQQ-NTKLELLAKKTSEMDPEKYFHFEELCQSL 329
+ ++ + ++ K ++E + E EK + E L Q L
Sbjct: 14692 TMMKMEKDQLEQAKSDIQRQMEEFERNMEETLKEKSRNEETLLQLL 14737
Score = 75.9 bits (185), Expect = 7e-11
Identities = 131/629 (20%), Positives = 268/629 (42%), Gaps = 25/629 (3%)
Frame = -2
Query: 2227 LDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++IQKE+ I E LK + + DL+ E+ +++I SL ELE ++ E + R++
Sbjct: 2720 VEIQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI-SLREELEEQSEKEGIDKTRVR 2778
Query: 2047 EAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRY 1868
+Q + E E R ++ ELE + + KQ + R +IE ++ EL +E K K R
Sbjct: 2779 -IKQEMDELEQTRLNVVKELENN-ELQKQIIEDERDKIEQIKAEL---QKEAKDTEKQRQ 2833
Query: 1867 QVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIE------QKE------ 1724
+ ++++ L +D + ++ D++ + L++ +E +KE
Sbjct: 2834 DIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDLKK 2893
Query: 1723 --VEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
E + E L + R ++I + ++K+ E +L+ +S+ ++ F++
Sbjct: 2894 TNTEMKDLEKQLESQNRQHEIQLAEIQKEREILE----QLKLTLSKQKEDLEKERDCFEK 2949
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFS-SVVKHLEYLKSQLETSNT 1373
E +S +L ++ E RE +T+V I++ +++ +VVK LE +N
Sbjct: 2950 EKADISLREELQEQSE---REGIGKTRVRIKKEMDELKQTRLNVVKELE--------NNE 2998
Query: 1372 MDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEE 1193
+ + + KA Q D + + E L+NE+ K +
Sbjct: 2999 LQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEK-KDIETST 3057
Query: 1192 YKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIE 1013
++ E N + E + +++ D+ K K ++ QL +++ +I+
Sbjct: 3058 DRIRDEEANLEVQKQRLESDR-----DTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQ 3112
Query: 1012 LVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELK--HANMSICSLSEKIQ 839
LVE +QKE I + + Q + + E + SLSE ++
Sbjct: 3113 LVE--------------IQKEREILEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLK 3158
Query: 838 QIEEREKV--LLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSH 665
+ ERE + T++ + +++ L QE K++++D D +E L+
Sbjct: 3159 EQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKE 3218
Query: 664 FNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEI---AHTS 494
+ + L N+ N EA + D+ E+++E + + I TE+ A+ S
Sbjct: 3219 AEKTKLELQNERQNLE-EAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANES 3277
Query: 493 DK---DEEVIKLQSQVENLQSLVQMLKQQ 416
+K + +I+L+ V ++ + L+ Q
Sbjct: 3278 NKQMQERVLIELKKTVTDIAGAKEDLENQ 3306
Score = 75.9 bits (185), Expect = 7e-11
Identities = 137/684 (20%), Positives = 276/684 (40%), Gaps = 75/684 (10%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L ++ ++ KEK E++K+ VK + ++ E++ + + + I +
Sbjct: 9125 LQQMKNELNKEKEQVEEMKQMVKTERVKIEQEKE----------EMRKQTQEIEDGHEKL 9174
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVL 1883
K+ + A++ L +A SE + LK +L + + +Q++ ++E+ ++ L++ + E+
Sbjct: 9175 QKKTEIADKLLQDANSESDRLK-DLSMKLQMQRQDIEKTNTEMETKKRSLDRMSREL--- 9230
Query: 1882 SKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRE 1703
Q L + Y + L K+ E+ E +E+K +++R+++
Sbjct: 9231 --------------QDDKIRLKNDRDAYEKDMTHLELKREELVRETEDLERKILQQREQD 9276
Query: 1702 CMLAASERSNDINVNALE-------KKLSAYEGKIRRLENDVSQLTL--------SVDFS 1568
M ++R + ALE KK + + ++ + ++ +L L +
Sbjct: 9277 EM---AKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQESELE 9333
Query: 1567 AGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQL 1388
VF EE + A +E L E+ E R +EE + LE K+Q+
Sbjct: 9334 NRVFMEEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQREKEQLEISKNQI 9393
Query: 1387 ETSNTMDHDTLSSTHQGSME----DKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLEN- 1223
E D + S + +E +KA+ + + + R++LEN
Sbjct: 9394 E-QEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENC 9452
Query: 1222 ---EECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNH 1052
E + K+MEE + +++E+ K ++ E I E+LL
Sbjct: 9453 WVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSR---ENIESREEKINNKMEELL--- 9506
Query: 1051 GQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDR------AMIAEGQ------ 908
Q++ EM K E+ +++ + A +D+EN + E+ +D+ I E +
Sbjct: 9507 -QMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQ 9565
Query: 907 --------SKAFQLELKHANMSICSLSEKIQQIE------EREKVLLTQLSTK-DTDMQH 773
S+ +L++K M + + + Q+IE E+EK L Q + + M
Sbjct: 9566 LDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMD 9625
Query: 772 LAAQLTLAQEE---ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLL----NQNVN--- 623
L + +EE + + K L+D E L + I+EM L Q +N
Sbjct: 9626 LTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQT 9685
Query: 622 -----YPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTE--DINTEIAHTSDKDEEVI--- 473
E+ F+ + + EI+ + E D++ E+ D+ E++
Sbjct: 9686 REENKKEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDELEKIAYKT 9745
Query: 472 -KLQSQVENLQ----SLVQMLKQQ 416
K + +VE +Q S +Q ++QQ
Sbjct: 9746 NKERHEVEQMQAELHSQIQAIEQQ 9769
Score = 75.1 bits (183), Expect = 1e-10
Identities = 124/623 (19%), Positives = 263/623 (42%), Gaps = 12/623 (1%)
Frame = -2
Query: 2203 ISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTLLE 2024
I ++KE +K ++SD D+ +K D + L E + K+ + L E
Sbjct: 4948 IKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLE----------KQRKIKLAE 4997
Query: 2023 AESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQVLELEEY 1844
+ ERE L+ ++ E ++ ++ Q++ + EL+Q E++ L + ELE+
Sbjct: 4998 IQKEREDLE-KMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQQ------ELEKE 5050
Query: 1843 SQQLSADLSKVHEDYSAALRQL-FDKKNEITCLQEVIEQKEVEERQRECMLAASERSNDI 1667
+ + D S++ LRQ DK+ T + +++E + E +Q L + +
Sbjct: 5051 KEIIMKDRSQLD------LRQSELDKQQ--TNVNDIMETMKNERKQ----LDKDKEETEE 5098
Query: 1666 NVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLRE 1487
+EK+ ++ + L+ D+ + L V ++E +K+ + E+E E
Sbjct: 5099 QKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQ----VLEDEKSKLE---QMKIELEREAVE 5151
Query: 1486 IRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQS 1307
IR + K IQ R N+E+ + +K ++ N D + ++ ++ D +S
Sbjct: 5152 IR-KIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKS 5210
Query: 1306 STGDNDPKAXXXXXXXXXXXECRQNL--ENEECKSK------QMEEYKMLQAELNNWLSC 1151
+ + R+N+ + E+ ++K + +E + LQAE++
Sbjct: 5211 NLEE-----------------MRENISKQTEDVENKKENLRLREDELRQLQAEIHK---- 5249
Query: 1150 MNAEMGKFLCLCNSMVYLEGD---ILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYA 980
E+ K + +E + I+K EDL L + SLK+ ++ F
Sbjct: 5250 QQREIEK------EKINIESERAAIIKDVEDLQHKIICLDRDAESLKL---DREAF---- 5296
Query: 979 VLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQL 800
EN ++ L K + + +LE +H + ++ +IQ+ + L+ +
Sbjct: 5297 ----ENEKEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDEINNLIEET 5352
Query: 799 STKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNY 620
+ KD + + + I S K+ML+ ++E + +S +++E L Q N
Sbjct: 5353 NRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKT----RSELYKVKEDLEKQKENT 5408
Query: 619 PLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQS 440
E + M+E ++ ++ +I + + K +E+ +L+++++NLQ
Sbjct: 5409 LAEIQKEREDLEKMNENIT---------REMHEIKHQEEQMNQKQDELDQLKTEIQNLQQ 5459
Query: 439 LVQMLKQQNTKLELLAKKTSEMD 371
++ K E++ K S++D
Sbjct: 5460 ELEKEK------EIIMKDRSQLD 5476
Score = 75.1 bits (183), Expect = 1e-10
Identities = 131/671 (19%), Positives = 280/671 (41%), Gaps = 33/671 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD ++ ++Q E E++K + +++++ EQ+ + I +LE + +
Sbjct: 10096 LDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGDLEIMRADYE-- 10153
Query: 2062 LKRLKEAEQTLLEAESERESL---KAELEESISVLKQELSSARLQIESLEKELNQANEEV 1892
K+ ++ E+ +EA+ ER+ L K+ELE+ + + E +EKE N
Sbjct: 10154 -KQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKERNDLE--- 10209
Query: 1891 KVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQ--KEVE 1718
K+ S+ Q ++E+ +L + + + + K++I +E++E+ EVE
Sbjct: 10210 KMKSELMTQRQQMEDERSELDQKIKEANTE-----------KDKIEKNKEIVERLMAEVE 10258
Query: 1717 ERQRECML----AASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
E++ + L A ER N ++ L L+ E +++ + + E
Sbjct: 10259 EQRNDFKLKKEELALERQNIVDEKYL---LAQCETELQNKSEQIRNM------------E 10303
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTM 1370
E+ K N + L+E E L+ + E K I+E E+ + + K +L+
Sbjct: 10304 EAVK--NERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKK-- 10359
Query: 1369 DHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEY 1190
DTL + Q + D + R+ E + K+MEE
Sbjct: 10360 --DTLEQEREEINHKWTQFQQRIDEFDAQV-------------RKQKEEDLTNQKKMEEE 10404
Query: 1189 KMLQAELNNWLSCMNA----EMGKFLCLCNSMVYLEGDILKYKED---LLLNHGQLRAEM 1031
+ E+N + M E + + L+ I+K KE + + R ++
Sbjct: 10405 RKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAMTIKLKMEREDL 10464
Query: 1030 SSLKIELVEKNGFMGYAVLDVENVQKEL-----LIWKDRAMIAEGQSKAFQLELKHANMS 866
+K ELV + +V++ QK+L +I +++ + + +S+ + +
Sbjct: 10465 DQIKSELVREK-------TEVDHEQKKLNDDIKMIEQEKEDLEKMKSE-IMTQKQEMEKE 10516
Query: 865 ICSLSEKIQQIE------EREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFI 704
L KIQQ + E+ K ++ +L + + +H ++ L +EE+ ++ + D
Sbjct: 10517 RSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRH---EIQLQKEELDIERQKIADEQ 10573
Query: 703 DNMEASDTNLQSHFNQIQEMLLNQNVNYPLEA--TVNIGFDQSMDEAVSEIAVQTFPNKD 530
D + + + LQ+ +I+ +N+ + E + ++ +E S +D
Sbjct: 10574 DLLIQNKSELQNENERIRN--INEVIKKERETLKEMEAHLEKEKEEMKSITEETRRQKED 10631
Query: 529 TEDINTEIAHTSDKDEEVIK----LQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEK 362
E ++T+I +++++++K L+ + E++ L+Q+ + + K E D K
Sbjct: 10632 LEKMSTDI---KEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQVSKQKEEDLTK 10688
Query: 361 YFHFEELCQSL 329
+E +SL
Sbjct: 10689 QKEMKEERKSL 10699
Score = 75.1 bits (183), Expect = 1e-10
Identities = 132/702 (18%), Positives = 287/702 (40%), Gaps = 68/702 (9%)
Frame = -2
Query: 2245 TLDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLST-------DRQSEIYSLSAELER 2087
TL + ++KEK + + E + + DL +K+ST D +S+ L E E
Sbjct: 11995 TLKEMEAYLEKEKEEMKSITEETRRQKEDL---EKMSTHINEQKQDLRSQRDLLEQEREE 12051
Query: 2086 ITQSEQMSLKRL--------KEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIE 1931
I + +R+ K+ E+ L + + +E K+ E ++L+ + + + E
Sbjct: 12052 INHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMK---TKAEPE 12108
Query: 1930 SLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITC 1751
++KE + EE ++ K + E+E Q+ + L +V + ++L D K I
Sbjct: 12109 EIKKEKEKEEEEQEMRVKVEMERKEIE----QIKSQLERVRSEMDHEQKKLNDDKKMIEQ 12164
Query: 1750 LQEVIE--QKEVEERQRECMLAASERSNDINVNALEK-KLSAYEGKIRRLENDVSQLTLS 1580
+E +E + E+ +++++ SE I LEK + + + +L +V +
Sbjct: 12165 EKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHE 12224
Query: 1579 VDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYL 1400
+ F E K+++ DLL ++ K+ Q ++E +K
Sbjct: 12225 IQFQKEELDIERQKIADEQDLL-----------IQNKIEQQNENERIKEMDEEIKKERET 12273
Query: 1399 KSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE 1220
++E + + + + S + + K + + D + + +Q+L N+
Sbjct: 12274 LKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQ--------------KQDLMNQ 12319
Query: 1219 ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGD-----------ILKYK 1073
KQ E E+N+ L+ + + +F N +V + + +K
Sbjct: 12320 RDLLKQERE------EMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEY 12373
Query: 1072 EDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQ 893
E ++ + R E+ ++++ ++N + +E +K+ K+R E Q +A
Sbjct: 12374 ESIIEETNRKRTELEEIEVDQSQQNKNVETMKDLLEKERKD--TEKER---EELQKQADD 12428
Query: 892 LELK------HANMSICSLSEKIQQIEEREKVLLTQ---LSTKDTDMQHLAAQLTLAQEE 740
LE++ MS SL E+ + +E++ +L Q L + DM +L Q+E
Sbjct: 12429 LEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKE 12488
Query: 739 ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSE 560
I + K +++ +E + +++E L N V + +++ + + E
Sbjct: 12489 IQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKHQQQ-IEE 12547
Query: 559 IAVQTFPNKDTED----------------------INTEIAHTS---DKDEEVIKLQSQ- 458
+ V+T +D D + E+ T D EE +KL+ Q
Sbjct: 12548 MRVKTKMERDELDQLMAKMLMDRKENERSKDMIGLLKKEMEQTKFNLDAQEEELKLEKQK 12607
Query: 457 VENLQSLVQM----LKQQNTKLELLAKKTSEMDPEKYFHFEE 344
++N + ++M +K++ ++++ L ++ E D + + +E
Sbjct: 12608 IQNEKKDLEMFKAEIKREASEVKTLKEQQLEKDTKAFEALKE 12649
Score = 75.1 bits (183), Expect = 1e-10
Identities = 125/644 (19%), Positives = 282/644 (43%), Gaps = 28/644 (4%)
Frame = -2
Query: 2218 QKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELE-RITQSEQMSLKRLKEA 2042
+KEK+ +++ ++++S ++ +L T+ ++I +++EL+ R + E + K+ KE
Sbjct: 13512 RKEKHAEAEIQRQFEDIES---VKVRLVTE-SNQIDKMNSELKTRSEELENLIKKQQKEF 13567
Query: 2041 EQTLLEAESERESLK---AELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFR 1871
E E + ER++L+ AELE + LK ++ + L+KE N+ E +L + +
Sbjct: 13568 ETKENEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREK 13627
Query: 1870 YQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-----TCLQEV-IEQKEVEERQ 1709
++ + + QQ ++ + + + + L +NE+ + L + +E+ E+++ +
Sbjct: 13628 SELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLK 13687
Query: 1708 RECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSN 1529
E + + + S + L++ E K +L+N + ++ + + +E+ +
Sbjct: 13688 TE--IQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMD---KLSIQREKDSLEEI 13742
Query: 1528 ACDLLQEIENFLREIRVETKVT--IQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTL 1355
DL ++ E E+R ++T I + +++ + L +++ +E + L
Sbjct: 13743 KADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQAKI----L 13798
Query: 1354 SSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSK-QMEEYKMLQ 1178
S Q +K + S +ND R++LE + ++ ++E + +
Sbjct: 13799 ESDVQLLQTEKEILEKSKTEND--------------LLREDLEKQRKRNDLTLQELRKEK 13844
Query: 1177 AELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKN 998
L ++ + E L N V L+ LK KE L + R EM L+++L +
Sbjct: 13845 MALEQMITDITKEKDAVASLQNE-VSLKQHELKNKETEL---DEQRKEMDDLRMQLEMRQ 13900
Query: 997 GFMG-----YAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELK----HANMSICSLSEK 845
V VEN++ + + ++ E + + Q +K N+ S ++
Sbjct: 13901 NSTNKQQQEVDVFIVENMKMRNDLESMKTLLDE-ERRQLQDNIKTFEDQKNVLHPSKTDA 13959
Query: 844 IQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSH 665
+QQ +E EK T + T+ ++ ++ + +EI +KE L+ +E +
Sbjct: 13960 VQQTDELEK-FTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGK 14018
Query: 664 FNQIQEMLLNQNVNYPLEATVNIGFD--QSMDEAVSEIAVQTFPNKDTEDINTEIAHTSD 491
QI+ + L A + G D +++ + ++A++ K ++ + +
Sbjct: 14019 RAQIESL-------EQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKN 14071
Query: 490 KDEEVIKL----QSQVENLQSLVQMLKQQNTKLELLAKKTSEMD 371
+ EE+ + QVEN + + + KQQ +++ SE D
Sbjct: 14072 ELEELRNTIEAEKHQVENRK--IMLDKQQKEVEDIMTVIKSERD 14113
Score = 72.8 bits (177), Expect = 6e-10
Identities = 145/702 (20%), Positives = 296/702 (42%), Gaps = 82/702 (11%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSE--------- 2072
+IQKE+ I E LK T+ + DL+ E+ +++I SL EL+ ++ E
Sbjct: 2918 EIQKEREILEQLKLTLSKQKEDLEKERDCFEKEKADI-SLREELQEQSEREGIGKTRVRI 2976
Query: 2071 --------QMSLKRLKEAEQTLLE---AESER---ESLKAELE---ESISVLKQELSSAR 1943
Q L +KE E L+ E ER E +KAEL+ E ++++ R
Sbjct: 2977 KKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDR 3036
Query: 1942 LQIESLEKELNQANEEVKV-LSKFRYQVLELEEYSQQLSAD-----------------LS 1817
E + +L ++++ + R + LE Q+L +D +
Sbjct: 3037 RNNEEMVIKLQNEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKERFDLEKTKTEMG 3096
Query: 1816 KVHEDYSAALRQLFDKKNEITCLQEVIE--------QKEVEERQRECMLAASERSNDINV 1661
+ + + +RQ + EI +E++E QKE E++R+C + DI++
Sbjct: 3097 NLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCF---EKEKADISL 3153
Query: 1660 NALEKKLSAYEGKIRRLENDVSQLTLSVD----FSAGVFKEESTK------VSNACDLLQ 1511
+ K+ S EG ++N +++ +D + KE+ + + D ++
Sbjct: 3154 SEDLKEQSEREG----IDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIE 3209
Query: 1510 EIENFLREIRVETKVTIQEARHNVEEFSSVVK----HLEYLKSQLETSNTMDHDTLSSTH 1343
+I+ L++ +TK+ +Q R N+EE + +K ++E L +L + + T
Sbjct: 3210 QIKAELKKEAEKTKLELQNERQNLEEAGTKLKKDRENVESLAEELGRKQVVLENMQIET- 3268
Query: 1342 QGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNN 1163
M+ KA ++S+ + +++LEN+ + + E+ K+ QAE+
Sbjct: 3269 --EMQRKA-NESNKQMQERVLIELKKTVTDIAGAKEDLENQLLEER--EKNKVKQAEI-- 3321
Query: 1162 WLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQL----------RAEMSSLKIE 1013
AE L + + DI+ E L L +L + E+ + +
Sbjct: 3322 -----QAEKDMLYLLKQGISEQQVDIVNKTEQLRLREVELEQLQALIYRQQDEIEANRKA 3376
Query: 1012 LVEKNGFMGYAVLDVENVQKEL-----LIWKDRAMIAEGQSKAFQLELKHANMSICSLSE 848
++ + + +++ +Q+E+ KDRA + + +S+ + KH M I L++
Sbjct: 3377 IINEKYRLEGQKTEIDRLQREVNQMMEYASKDRANLEKEKSE--MIAQKH-QMDI-ELNK 3432
Query: 847 KIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQS 668
+ IEER ++ L+T + +M L + +E+ K+ +++ + ++ LQ
Sbjct: 3433 ERGLIEERTQM----LNTYEKEMDQKRTALEVEMKELKYHKQAIQEEKNKLQQMKIELQR 3488
Query: 667 HFNQIQEML-LNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSD 491
+ I+++ +N LE ++ D+ ++ +A T D + E A +D
Sbjct: 3489 EADDIKKLKEKTRNERQSLEKMAE-NLEKEKDD-LAHLAEDTKRKDDEMKVLHESA-LAD 3545
Query: 490 KDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPE 365
+E L+ E++ +M+ + K+ L K +M E
Sbjct: 3546 IQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQQMQAE 3587
Score = 70.9 bits (172), Expect = 2e-09
Identities = 105/631 (16%), Positives = 253/631 (40%), Gaps = 12/631 (1%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L+ V +IQ+EK + + + +L+ + +RQ +I + +LE E+
Sbjct: 9903 LNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLE-----EEKL 9957
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEES-ISVLKQELSSARLQIESLE---KELNQANEE 1895
L +++ + E +R+ K E+ E+ + V+K++ +AR + E + +E Q NE
Sbjct: 9958 LVQIEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNEN 10017
Query: 1894 VKVL-----SKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-TCLQEVIE 1733
K L Q EL++ + L + E+ + R L ++K + E++
Sbjct: 10018 AKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILR 10077
Query: 1732 QKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFK 1553
Q++ E+++E M+ KL + +++ + ++ +D
Sbjct: 10078 QRDDLEKEKEDMMKK------------WNKLDVLQNEMQNENKAMEEIKYELDGKRNEIN 10125
Query: 1552 EESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNT 1373
+E ++ + + E + L +R + + Q+ E K L+ +KS+LE T
Sbjct: 10126 KEQQRLEESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKT 10185
Query: 1372 -MDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQME 1196
+D++ + +M +K + ++ RQ +E+E
Sbjct: 10186 EIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQ------------RQQMEDE-------- 10225
Query: 1195 EYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKI 1016
++EL+ + N E K + L ++ + + D L +L E +
Sbjct: 10226 -----RSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQRNDFKLKKEELALERQN--- 10277
Query: 1015 ELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQ 836
+V++ + +++N +++ + + +K+ ++ +Q+
Sbjct: 10278 -IVDEKYLLAQCETELQNKSEQI--------------RNMEEAVKNERETLKETEAHLQR 10322
Query: 835 IEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQ 656
++ K ++ + S + D++ ++ + + ++E+ + K+ L+ + + T Q ++
Sbjct: 10323 DKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDE 10382
Query: 655 IQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDE-E 479
+ Q ++ + M+E K E++N +I K E E
Sbjct: 10383 FDAQVRKQKEE-------DLTNQKKMEE----------ERKCLEEVNGKIIEMKTKAELE 10425
Query: 478 VIKLQSQVENLQSLVQMLKQQNTKLELLAKK 386
++ ++E LQ+L + + ++ K E + K
Sbjct: 10426 HHEINQKIEELQTLQEQIMKEKEKAEAMTIK 10456
Score = 70.5 bits (171), Expect = 3e-09
Identities = 135/717 (18%), Positives = 295/717 (41%), Gaps = 94/717 (13%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKETVKNLQSD-------LDIEQKLSTDRQSEIYSLSAELERIT 2081
D R DI+ K I + L V+ + D LDIE++ D Q + A+L+
Sbjct: 11642 DLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNEN 11701
Query: 2080 QSEQMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQAN 1901
+ + + +K+ ++TL E E+ L+ E EE SV+++ + +E + ++N+ N
Sbjct: 11702 ERIKEMDEEIKKEKETLKEMEAH---LRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQN 11758
Query: 1900 EEV----KVLSKFRYQV----LELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQ 1745
+++ +L + R ++ +L++ + A +SK E+ +++ +++ + +
Sbjct: 11759 QDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETK 11818
Query: 1744 -EVIE----------QKEVEERQRECMLAASERSND-------------INVNALEKKLS 1637
++IE +KE E+ + E M A E + ++ +KKL+
Sbjct: 11819 IKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLN 11878
Query: 1636 AYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSN--------ACDLLQEIENFLREIR 1481
+ I + + D+ ++ + +EE +++ N CD IEN +EI
Sbjct: 11879 DDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCD----IEN-SKEIV 11933
Query: 1480 VETKVTIQEARHNVE--------EFSSVVKHLEYL---KSQLETSN----------TMDH 1364
+ V ++E +H ++ E + + L KS+L+ N +
Sbjct: 11934 QKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKER 11993
Query: 1363 DTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEE--- 1193
+TL ++K +S T + + E +Q+L ++ +Q E
Sbjct: 11994 ETLKEMEAYLEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEIN 12053
Query: 1192 --YKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLK 1019
+K LQ ++ + + ++ + + L M + + K ++L + +AE +K
Sbjct: 12054 HKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANIL--EMKTKAEPEEIK 12111
Query: 1018 IELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQ 839
E EK + VE +KE+ K + + Q +L I E ++
Sbjct: 12112 KE-KEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLE 12170
Query: 838 QIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFN 659
+++ Q+ + +++ Q L + +I ++KE+++ + +E +Q
Sbjct: 12171 KMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKE 12230
Query: 658 QI----------QEMLLNQNVNYPLEATVNIGFDQSMD---EAVSEIAVQTFPNKDTEDI 518
++ Q++L+ + E D+ + E + E+ V K+ E+I
Sbjct: 12231 ELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNL--QKEKEEI 12288
Query: 517 NTEIAHTSDKDEEVIKLQS----QVENLQSLVQMLKQQ----NTKLELLAKKTSEMD 371
+ I T + E++ K+ + Q ++L + +LKQ+ N KL L ++ E +
Sbjct: 12289 ESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFE 12345
Score = 67.4 bits (163), Expect = 3e-08
Identities = 132/650 (20%), Positives = 266/650 (40%), Gaps = 34/650 (5%)
Frame = -2
Query: 2224 DIQKEK-NISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
+I EK NI + ++ Q+ + +K S D + ++ + E E + + K ++
Sbjct: 6803 EIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVE 6862
Query: 2047 EAEQTLLEAESERESLKAE---LEESISVLKQELSSARLQIESLEK-ELNQANEEVKVLS 1880
+ +Q L+ E + ESLK + E +KQ + ++Q + +EK +L +E +V
Sbjct: 6863 DLQQKLMSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRV-- 6920
Query: 1879 KFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-TCLQEVIEQKEVEERQRE 1703
++ +A + K E+ + + ++ K++ I E+ ++KE E R
Sbjct: 6921 -------------EEKTAQIQKEREEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRS 6967
Query: 1702 CMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNAC 1523
+ A ++ N N +E L+ + K LE +S + S K E
Sbjct: 6968 DLEKAKSQTFKQNKN-IEIALAEIQQKRNALEK------MSKEISRDRMKLE-------- 7012
Query: 1522 DLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTH 1343
+ K IQ AR +E ++ + K L S D L +
Sbjct: 7013 ---------------DEKKEIQLAREELERMHGDMQRQQEAKDHL-LSGITDESLLKKSE 7056
Query: 1342 -----QGSMEDKA----SSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEEC-------- 1214
Q S DKA ++ S D P +++ E+E+
Sbjct: 7057 AEIVLQPSQVDKAKPARKTEISDSDKQPVFVQQMPEMDLKDALKKDFESEKLDLPKVKDV 7116
Query: 1213 --KSKQME-EYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQL 1043
+ +QM+ E K+++ E++ L M AE+ K E D ++ K+ + N Q
Sbjct: 7117 LPQDQQMKLEQKLIEDEMDK-LKQMRAELQK-----------EADQIEKKKQDMQNERQK 7164
Query: 1042 RAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLE---LKHAN 872
+M++ E N E + +E+ I K + + Q+ AFQ+E +
Sbjct: 7165 LDDMAARLQEERRTN----------ERLNEEINIQK---VNQQKQATAFQMEKTDFERIK 7211
Query: 871 MSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNME 692
I ++++ +E+ K +T++ + ++ + A ++ E I++ + L
Sbjct: 7212 TEIDQANKELADQQEKNKKTITEMQKERETLEEMRANISKQVETITNENKSL-------- 7263
Query: 691 ASDTNLQSHFNQIQEMLLNQNVNY-PLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDI- 518
++ +S ++QE +L Q L+ T+ + Q +D+ S+I + K+ +D+
Sbjct: 7264 ---SSRESELAKLQEDILQQQQEMDELKNTIMMEMCQ-LDQRQSDIDLL---QKEVDDLM 7316
Query: 517 ---NTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSE 377
TE+A+ + E +++ +Q N++S + LK + E L K +E
Sbjct: 7317 DFTKTEMANV---ERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNE 7363
Score = 67.0 bits (162), Expect = 3e-08
Identities = 116/631 (18%), Positives = 263/631 (41%), Gaps = 25/631 (3%)
Frame = -2
Query: 2188 KETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTLLEAESER 2009
+E + +++++DIE+ + + ELE+I Q +AE E
Sbjct: 13121 REELAKMKTEIDIERDEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQHDEIHGGI 13180
Query: 2008 ESLKAELEESISVLKQELSSARLQIESLEKELNQANEEV-KVLSKFRYQVLELE--EYSQ 1838
+SLK E EE I +K +L + + E++ + + +E+ K ++ +E E + +
Sbjct: 13181 DSLKEEREE-IEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDK 13239
Query: 1837 QLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVN 1658
L ++ K+ A L+ +KN + + E + +E E + C + E++ ++N
Sbjct: 13240 NLQDEMMKI----EAILKVTKKQKNYLEQMNENL-TREKTELETNCQMLEREKT-ELNKK 13293
Query: 1657 ALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRV 1478
E + + K+ E + + +D A EE K+ +E+ N EI+
Sbjct: 13294 VKETE-EFHMSKMEEREAERKTIERVMDEMA----EEHEKIKKE---REELVNMEEEIKK 13345
Query: 1477 ETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTG 1298
+ +V ++ E + L++ +S+L D ++S + ++ + S Q
Sbjct: 13346 QRRV----LEESMNEMTKKKSELQHERSELYKQKQQLEDMIASESKRDVDTERSRQDKED 13401
Query: 1297 DNDPKAXXXXXXXXXXXECRQNLENEECK---SKQMEEYKMLQAELNNWLSCMNAEMGKF 1127
+ K ++ + E K +++ E + +Q++LN+ M+ E K
Sbjct: 13402 EQILKREREEIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKL 13461
Query: 1126 LCL-------CNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDV 968
L + N++ + D+ K +E++ Q + E I + E +A ++
Sbjct: 13462 LYMKTEIQVKTNALEKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEI 13521
Query: 967 ENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKD 788
+ +++ K R + Q ELK + SE+++ + ++++ + TK+
Sbjct: 13522 QRQFEDIESVKVRLVTESNQIDKMNSELK-------TRSEELENLIKKQQ---KEFETKE 13571
Query: 787 TDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEM--LLNQNVNYPL 614
+MQ L E+ LK+ I+ + + +LQ N+ +E+ +L + +
Sbjct: 13572 NEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREKSELY 13631
Query: 613 EATVNIGFDQSMDEAVSEIA------VQTFPNKDTEDINTEIAHTSDKDEEVIKL----Q 464
+ + + E + + ++ N+ ++ + ++ S + E+ KL Q
Sbjct: 13632 QEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTEIQ 13691
Query: 463 SQVENLQSLVQMLKQQNTKLELLAKKTSEMD 371
S+ E+++ + LKQ + E K +++D
Sbjct: 13692 SEKESIEEEKKTLKQLKDENE---SKRTQLD 13719
Score = 65.9 bits (159), Expect = 7e-08
Identities = 135/678 (19%), Positives = 282/678 (41%), Gaps = 63/678 (9%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKE-------TVKNLQSDLDIEQKLSTDRQSEIYSLSAELERIT 2081
D + I KEK S ++E T + + +++ E++ RQ E+ E+ERI
Sbjct: 546 DVEKAKILKEKEESIRIREEARQERETTELVNAEIKAEKERLNQRQEEMLRERQEIERIK 605
Query: 2080 QSEQMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQAN 1901
+ + ++ ++ + + E +KAE++ I +++++ + E +E+ +
Sbjct: 606 HETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKEQMEEAKVELE 665
Query: 1900 EEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITC---------- 1751
EE + L + R V E ++ L ++ +V E+ + R+ ++ E+
Sbjct: 666 EEREDLERKRDLVSREIEQAEFLRNEILRVKEEMESRWRETETEEVELRAKTQHELERLE 725
Query: 1750 -LQEVIE--QKEVEERQRECML-------AASERSNDINVNALEKKLSAYEGKIRRLEND 1601
L+E E QK +EE + E ML E D +V ++ ++ + K +L
Sbjct: 726 KLREETERSQKNIEESKIELMLWKESLDKLKGEMEEDKHVVIMQ--MNEAKAKEEQLTMV 783
Query: 1600 VSQLTL---SVDFSAGVFKEESTKVSNACDLLQ----EIENFLREIRVETKVTIQEARHN 1442
+ QL + + S KEE +++ + LQ E+E++ R + E K A+
Sbjct: 784 IEQLEIERGEITISREKVKEELDEINRMRNELQRQHAEMEDWFRVVNKE-KEEANLAKLA 842
Query: 1441 VEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXX 1262
V E + LK Q+E S ++ ++ ++E + Q KA
Sbjct: 843 VHEAEML------LKKQMEESEKRRYEMITE----ALEQRDEIQK-------KAEELEQI 885
Query: 1261 XXXXXECRQNLE-----NEECKSKQME---EYKMLQAELNNWLSCMNAEMGKFLCLCNS- 1109
RQ LE +E K +E + ++ ++ + L A+ K L +S
Sbjct: 886 NKEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLFEMDSE 945
Query: 1108 ---MVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLI- 941
+ + + K+DL Q R EM VE++ + ++E ++ +L+I
Sbjct: 946 RKELEQMRFQVENEKKDL----EQRRYEMMRYD---VEQSAQVQRQKEELEKIKSQLVID 998
Query: 940 ----WKDRAMIAEGQSKAFQL--ELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDM 779
+ R + + + KA L E++ + E+ +Q EE ++L + + D+
Sbjct: 999 TESMNRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRLLRKDMENEREDL 1058
Query: 778 QHLAAQLTL--------AQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVN 623
+ + + TL +EEI+ + ++ D E D + N +E ++ +
Sbjct: 1059 EKIRVE-TLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRK--- 1114
Query: 622 YPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIK--LQSQVEN 449
+EA + M E + ++ V+ K+ D+ E A + E++K L Q E+
Sbjct: 1115 --MEA-----MKREMGE-IEDMKVELTKQKENIDMKMEHARLEMTNLEMMKADLLRQKED 1166
Query: 448 LQSLVQMLKQQNTKLELL 395
+++ + K + ++E++
Sbjct: 1167 IENQMLAAKSERQQMEVM 1184
Score = 65.5 bits (158), Expect = 1e-07
Identities = 142/774 (18%), Positives = 319/774 (41%), Gaps = 66/774 (8%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
+++ ++ + ED K ++N++ +L E + ++ +E + + + L++
Sbjct: 1805 NLEAQRKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEK 1864
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQ 1865
+ + ++ER +LE + + L+ + + + LEK +++ N + K +
Sbjct: 1865 KRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEK-ISELNSQQKDEIENEKS 1923
Query: 1864 VLELEEYS-QQLSADLSKVHEDYSAALRQLFDKKNEITCLQ-EVIEQ-KEVEERQRECML 1694
+++ EY QQ+ DL++ ++ +F +K+E+ Q E+ EQ K+V + +
Sbjct: 1924 KIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQDEIAEQLKQVGDMMQ---F 1980
Query: 1693 AASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLL 1514
+E+ N L+++ +A + ++E D++ L S + K+E V N LL
Sbjct: 1981 TQNEKDN------LDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKE---VLNEKRLL 2031
Query: 1513 QEIE-NFLREIR--VETKVTIQEARHNVE-EFSSVVKHLEYLKSQLET----SNTMDHDT 1358
++ + +R+++ + K+ ++ + ++ + S+ + + L+S L+T + + DT
Sbjct: 2032 EDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDT 2091
Query: 1357 LSSTHQGSMEDKA---------------SSQSSTGDNDPKAXXXXXXXXXXXECRQNLEN 1223
L+ + +ED A ++ D D + + +L+
Sbjct: 2092 LAEKQK--LEDAAVELQKERDEIMNIAEETKRKREDVDKIRVGIEKQEITFKDLKADLQK 2149
Query: 1222 E--------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKED 1067
E + K ++ K ++ ++ M+ + + ++ ++ ++ K +++
Sbjct: 2150 EAAIVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVDKERQE 2209
Query: 1066 LLLNHGQLRAEMSSLKIE------LVEKNGFMGYAV--------LDVENVQKELLIWKDR 929
+ +L E S L+ + EKN + + L EN+ KE I
Sbjct: 2210 VESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTI---- 2265
Query: 928 AMIAEGQSKAFQLELKHANMSICSLSEKIQQIEE------REKVLLTQLSTKDTDMQHLA 767
F+LE +H + K +QI+E EKV + Q+ D D Q
Sbjct: 2266 ----------FELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQA-DKDQQRKK 2314
Query: 766 AQL--------TLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLE 611
A+ T A EE E L++ +N+E + H N+ +E+ ++ + +E
Sbjct: 2315 AEYVKTARGRETTALEEQRQEMESLREEYENVEKQ----KKHVNEQKELFESRMKSLEME 2370
Query: 610 ATVNIGFDQSMDEAVSEIAVQ-TFPNKDTEDINTEIAHTSDKDEEVIK-LQSQVENLQSL 437
+ + +D+ ++ Q K+ + + TE+ ++ E K L+ Q + +
Sbjct: 2371 NEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTE 2430
Query: 436 VQMLKQQNTKLELLAKKTSEMDPEKYFHFEELCQSLVXXXXXXXXXXXXXXXKNQVLVKQ 257
ML+ Q +E KT E+D + +L S V + + VK+
Sbjct: 2431 TYMLETQKPVVE--KSKTDELDEVRKKINADL--SEVEKQKSALVQMNLKISQEESYVKK 2486
Query: 256 VKEMQVTLQSESPMEGETDSISENAIGSQPA--GKLSTELHNVHGNTERVPLQL 101
K+ ++E M+ + +N + + A K EL NV E+ +++
Sbjct: 2487 EKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEI 2540
Score = 65.5 bits (158), Expect = 1e-07
Identities = 135/673 (20%), Positives = 272/673 (40%), Gaps = 57/673 (8%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQ--------KLSTDR---QSEIYSLSAELERITQ 2078
D+QKEKN +E+LK ++ +S+L E+ ++ T R +SE+ +L +
Sbjct: 13608 DLQKEKNKTEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELED 13667
Query: 2077 SEQMSLKRLK----EAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELN 1910
++ L RL E ++ E +SE+ES++ E ++++ LK E S R Q+++ +++N
Sbjct: 13668 EKKSMLSRLSMEKHEIDKLKTEIQSEKESIEEE-KKTLKQLKDENESKRTQLDNTIEKMN 13726
Query: 1909 ----------QANEEVKVLSKFRYQVLELE-----EYSQQLSADLSKVHED--------- 1802
+ EE+K + + + L+ E + + Q+S D + +D
Sbjct: 13727 MDKLSIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRS 13786
Query: 1801 -YSAALRQLFDKKNEITCLQ---EVIEQKEVEERQRECMLAASERSNDINVNALEKKLSA 1634
+ RQ ++++ LQ E++E+ + E L + ND+ + L K+ A
Sbjct: 13787 MRADIERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEKQRKRNDLTLQELRKEKMA 13846
Query: 1633 YEGKIRRLEND---VSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVT 1463
E I + + V+ L V K + T++ + ++ L + T
Sbjct: 13847 LEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQ 13906
Query: 1462 IQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPK 1283
QE + E + LE +K+ L+ D + + S + D
Sbjct: 13907 QQEVDVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDEL 13966
Query: 1282 AXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMV 1103
+ E + +K++ + K LN + E+ S+
Sbjct: 13967 EKFTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLE 14026
Query: 1102 YLEGDILKYKED---LLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWK- 935
L D+L +D L+ Q+ E + K E VE + ++E ++ + K
Sbjct: 14027 QLRADLLAGADDIKTLVQTEKQMAIEDTEKKTE-VELQMNLQKQKNELEELRNTIEAEKH 14085
Query: 934 ---DRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAA 764
+R ++ + Q K + I ++ + + + E+EK L +LS L
Sbjct: 14086 QVENRKIMLDKQQKEVE--------DIMTVIKSERDVLEKEKSELNKLS------HVLNE 14131
Query: 763 QLTLAQEEISSTKEMLKDFIDN----MEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNI 596
++ QEE+ E +D I+N +E+ +++ +++ L + V E T+ +
Sbjct: 14132 KVQREQEELERLLEKERDDIENCKKIIESEKQSIERERAELKR--LKEEVEVQHERTL-L 14188
Query: 595 GFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQ 416
D++M + K+ E + E A T+ EE+ L+ +++ S + ML +
Sbjct: 14189 QQDKNMIQ------------KEKEHLEGEKARTT---EEIHNLKEEIKRKSSELDMLNK- 14232
Query: 415 NTKLELLAKKTSE 377
E+ AK+ E
Sbjct: 14233 ----EIEAKRQEE 14241
Score = 64.7 bits (156), Expect = 2e-07
Identities = 117/652 (17%), Positives = 266/652 (40%), Gaps = 26/652 (3%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L+ + D+QK K +E + L+ + QSE+ SL+ E++ + Q +
Sbjct: 14550 LNKAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIK--- 14606
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVL---KQELSSARLQIESLEKELNQANEEV 1892
E +Q ++ + + S+ + E + + ++ + + + E+E++ +
Sbjct: 14607 ----TEMQQIEIKMQIQTRSVATQWETDVQIQQEGQEPIETTGHITKKSEEEISAKKTKQ 14662
Query: 1891 KVLSKFRYQVL-ELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVE- 1718
+++K + E++E D++++ QL K++I E E+ E
Sbjct: 14663 PIVTKLEDTLTSEVQEMRDMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEET 14722
Query: 1717 ----ERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
R E +L +D++ N L++K E + +++QL ++ + K+
Sbjct: 14723 LKEKSRNEETLLQLLHDKDDLS-NTLDEKSKEIENITVTFKRNIAQLETTI----AMMKK 14777
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTM 1370
+ + N L++ E REI+ T T E E + V + L+ E
Sbjct: 14778 DKENIENELLQLKQTEQ-EREIQRGTDDTSNER----ENYDEKVTYKTELEDSKEKKKPD 14832
Query: 1369 DHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-ECKSKQMEE 1193
+L T S + ++ T + K + ++ L +E E K K + E
Sbjct: 14833 RDSSLKLTDADSAKTDGEREAQT--LETKVQDVLQLTDYTTQDQEELHDEMENKMKIILE 14890
Query: 1192 YKMLQAELNNWL-SCMNAEMGKFLCL------CNSMVYLEGDILKYKEDLLLNH-GQLRA 1037
+ +L C +AE K + + NS+ ++ ++L ++ ++H Q++
Sbjct: 14891 LNEAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQE--IDHLAQIKT 14948
Query: 1036 EMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICS 857
EM ++I++ + +V + W+ I +GQ E I
Sbjct: 14949 EMQQIEIKM----------QIQTRSVATQ---WETDVQIQQGQ------EATETTGHITK 14989
Query: 856 LSEKIQQIEEREKVLLTQL-STKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDT 680
SE+ ++ ++ +T+L T +++Q + L E+++ K ++K D +E + +
Sbjct: 14990 KSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVARMKTIMKMEKDQLEQAKS 15049
Query: 679 NLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAH 500
++Q+ + F+++M+EA+ E + ++++
Sbjct: 15050 DIQTQMEE---------------------FERNMEEAMEEKSRNEEKLLQLTHDKEDLSN 15088
Query: 499 TSDKDEEVIKLQSQ-----VENLQSLVQMLK--QQNTKLELLAKKTSEMDPE 365
T DK + I+ ++ + L++ + ++K ++N + ELL K +E + E
Sbjct: 15089 TLDKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQERE 15140
Score = 63.9 bits (154), Expect = 3e-07
Identities = 125/676 (18%), Positives = 275/676 (40%), Gaps = 49/676 (7%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDL-------KETVKNLQSDLDIEQKLSTDRQSEIYSL-SAELER 2087
++ + D+Q E+ +D+ + T + L +++I QK++ +Q+ + + + ER
Sbjct: 7151 IEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINI-QKVNQQKQATAFQMEKTDFER 7209
Query: 2086 ITQSEQMSLKRLKEAEQ----TLLEAESERESLKAELEESISVLKQELSSARLQIESLEK 1919
I + K L + ++ T+ E + ERE+L+ E+ +IS + +++ + S E
Sbjct: 7210 IKTEIDQANKELADQQEKNKKTITEMQKERETLE-EMRANISKQVETITNENKSLSSRES 7268
Query: 1918 ELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEV 1739
EL + E++ Q E++E + ++ QL ++++I LQ+
Sbjct: 7269 ELAKLQEDI------LQQQQEMDELKNTIMMEMC-----------QLDQRQSDIDLLQKE 7311
Query: 1738 I---------EQKEVEERQRECMLAASERSNDINVNALEK------KLSAYEGKIRRLEN 1604
+ E VE + E + +D+ +EK +L E K +E
Sbjct: 7312 VDDLMDFTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNEEK-DLIEK 7370
Query: 1603 DVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS 1424
+ LT ++D + + ++ N + I+N +E+ + K+++Q +EFS
Sbjct: 7371 ERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKELE-KMKISLQRKAIGFKEFSE 7429
Query: 1423 VVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXE 1244
K + ++ T D +G ++ Q+ + K E
Sbjct: 7430 KTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQT-----EKKRRKTYYTEDLFQE 7484
Query: 1243 CRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL 1064
+ +L+ K EE + E+ + +N E + S + +I K KE +
Sbjct: 7485 EKTDLQ------KTKEEINYDREEIYRQRTELNKEKETLKQMHTSNLKEIENIEKEKEKI 7538
Query: 1063 LLNHG---QLRAEMSSLKIELVEKNGFM----GYAVLDVENVQKELLIWKDRAMIAEGQS 905
Q+RAE+ + + ++ + M D+EN+Q E KD +
Sbjct: 7539 QRTWNELDQIRAELQNKQRDMDDTTNIMMKEKAELARDLENLQNE----KDELQKSRENI 7594
Query: 904 KAFQLELKHANMSIC-SLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISST 728
+ EL+ + +L+++ QQ E ++ K+ + + A++ + + +
Sbjct: 7595 QKLMKELQEERLKTSEALNKERQQFTE-------EIKLKNDSLDEIQAEIDRQKRALVTD 7647
Query: 727 KEML-KDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNI-----GFDQSMDEAV 566
KE++ K +D + D QS + I L + + +V I ++ DE +
Sbjct: 7648 KEIITKQMMDLQKTQDVRRQSDESDIARANLQRERESLDQLSVEILKQKQDLERERDELL 7707
Query: 565 SE---IAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQ-----VENLQSLVQMLKQQNT 410
+ + Q N++ + + TE+ + E++ K Q EN +L + L++ N
Sbjct: 7708 EQWRLVETQKMDNENVKQLKTELLDEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNL 7767
Query: 409 KLELLAKKTSEMDPEK 362
+ + + + ++++ K
Sbjct: 7768 QKQGIQDERAQLERMK 7783
Score = 63.9 bits (154), Expect = 3e-07
Identities = 130/706 (18%), Positives = 276/706 (39%), Gaps = 79/706 (11%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLD--------IEQKLSTDR------------- 2126
++ +R DI +EKN ++ +SDL+ +Q + +R
Sbjct: 12837 IEKIRQDIDREKN-------DLEKYRSDLEKQYEEMEICKQNIENERAELEIDLENIIIE 12889
Query: 2125 ----QSEIYSLSAELE---------------RITQSEQMSLKRLKEAEQTLLEAESERES 2003
Q + S+ +L+ R + + + K +E EQ E E++
Sbjct: 12890 TKSKQERLESIEVQLQEKNVQMGTILDELNKRQEELDAIKAKTQREKEQMGHTEELEKDE 12949
Query: 2002 LKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSAD 1823
L A L++ ++K+ + + Q E L+KE +Q L K + LE+E + L+++
Sbjct: 12950 LIAILQKREEIVKRHMEEIQNQREELQKEKDQFGNMQAELQKGQ---LEMEMHQLMLNSE 13006
Query: 1822 ----------LSKVHEDYSAALRQLFDKKNEITCLQEVI-EQKEVEERQRECMLAASERS 1676
L K E++ + L ++ E + L++++ E+K VEE M A +
Sbjct: 13007 RDELNGMRVNLEKQKEEFELMQQNLESRRPE-SLLEDILKEKKRVEE-----MAAQLSKE 13060
Query: 1675 NDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDL----LQE 1508
+ N + + + E KI+++E ++ + + + ++E + N + LQ
Sbjct: 13061 QEEFRNIMSETIKRME-KIKQIEGEIKTKQIEMACLEELKQKELDEQKNMRECENQELQM 13119
Query: 1507 IENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSN------TMDHDTLSST 1346
L +++ E + E + +++ LE +K L+ + HD +
Sbjct: 13120 RREELAKMKTEIDIERDEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQHDEIHGG 13179
Query: 1345 HQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELN 1166
E++ + D K + LE +E + +QM ++ E N
Sbjct: 13180 IDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQM----AVETEDN 13235
Query: 1165 NWLSCMNAEMGKFLCLC-------NSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELV 1007
+ + EM K + N + + ++ + K +L N L E + L ++
Sbjct: 13236 DSDKNLQDEMMKIEAILKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNKKVK 13295
Query: 1006 EKNGFMGYAVLDVENVQKELLIWKDRAM--IAEGQSKAFQLELKHANMSICSLSEKIQQI 833
E F + + E +K + +R M +AE K +K + ++ E+I++
Sbjct: 13296 ETEEFHMSKMEEREAERKTI----ERVMDEMAEEHEK-----IKKEREELVNMEEEIKKQ 13346
Query: 832 EEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQ-SHFNQ 656
+ + +++ K +++QH + E+ K+ L+D I + D + + S ++
Sbjct: 13347 RRVLEESMNEMTKKKSELQH-------ERSELYKQKQQLEDMIASESKRDVDTERSRQDK 13399
Query: 655 IQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEV 476
E +L + E ++++ Q K+ ED+ T + + E +
Sbjct: 13400 EDEQILKRE-----------------REEIADMKDQLL--KEKEDVETTKERINREKEHI 13440
Query: 475 IKLQSQVENL--------QSLVQMLKQQNTKLELLAKKTSEMDPEK 362
K+QSQ+ + Q L+ M + K L K ++ E+
Sbjct: 13441 EKMQSQLNDQKEEMDLENQKLLYMKTEIQVKTNALEKMMQDLQKER 13486
Score = 63.5 bits (153), Expect = 4e-07
Identities = 110/654 (16%), Positives = 277/654 (42%), Gaps = 44/654 (6%)
Frame = -2
Query: 2230 RLDIQKEKNISEDL-------KETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSE 2072
+ DI+ K I + L K ++ + +LDIE++ D Q + +EL+ +
Sbjct: 10809 KCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERI 10868
Query: 2071 QMSLKRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKEL-NQA 1904
+ + +K+ +TL E E+ E K E++ E LK++L + K+L NQ
Sbjct: 10869 RNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRLKEDLEKMSTDVNKQNKDLMNQR 10928
Query: 1903 N----EEVKVLSKFRYQVLELEEYSQQLS----ADLSKVHEDYSAALRQLFDKKNEITCL 1748
+ E ++ K++ ++E+ Q+S DL K + + L + K + +
Sbjct: 10929 DLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPK-EKGMKEDRKSLEETKANVIEM 10987
Query: 1747 QEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFS 1568
+ E +E+++ + + E +I V ++ Y+ +++++ ++ +D
Sbjct: 10988 KTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELYQ-----IKSELERVRSEID-- 11040
Query: 1567 AGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQL 1388
E K+++ ++++ + L +++ E Q+ E + ++ K +
Sbjct: 11041 -----HEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDI 11095
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKS 1208
E S + + E + Q + D + + + L+NE +
Sbjct: 11096 EKSKEIVEKLMVEVE----EQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERI 11151
Query: 1207 KQM-EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEM 1031
K++ EE K + L + E + + + D+ K D+ L+ +
Sbjct: 11152 KKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQR 11211
Query: 1030 SSLKIELVEKNGFMGYAVLDVE------NVQKELL----IWKDRAMIAEGQSKAFQLELK 881
L+ E E N M ++ + Q+E L + ++R + E +++ +++ K
Sbjct: 11212 DLLEQEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTK 11271
Query: 880 HANMSICSLSEKIQQIEEREKVLL----TQLSTKDTDMQHLAAQLTLAQEEISSTKEMLK 713
I + EK ++ EE +V++ +L+ ++++ + +++ Q++++ K++++
Sbjct: 11272 AELQEI--MQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIE 11329
Query: 712 DFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFD-QSMDEAVSEIAVQTFPN 536
+++E + + + Q++E ++ ++ T D ++ E V ++ V+
Sbjct: 11330 QEKEDLEKMKSEIMTQRQQMEEE--RSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQ 11387
Query: 535 K-----DTEDINTEIAHTSDKDEEVI----KLQSQVENLQSLVQMLKQQNTKLE 401
+ E+++ E +D+ V+ KLQ++ E ++ + + +K++ L+
Sbjct: 11388 RKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLK 11441
>ref|XP_005159738.1| PREDICTED: titin isoform X1 [Danio rerio]
Length = 15746
Score = 105 bits (261), Expect = 1e-19
Identities = 135/637 (21%), Positives = 287/637 (45%), Gaps = 30/637 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD + ++ K++ D+ ET+KN + LD +++ +++ EI + ++ S
Sbjct: 3530 LDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDED 3589
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEE---SISVLKQELSSARLQIESLEKELNQANEEV 1892
LK +K +Q E +++ E +K ELE I +K+E+ + R +E + +EL + E
Sbjct: 3590 LKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESF 3649
Query: 1891 KVL---SKFRYQVL-ELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKE 1724
L +K ++L E++ ++ L A+L K ++ + + ++ +E + +E
Sbjct: 3650 THLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLRE 3709
Query: 1723 VEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEES 1544
E Q + + +R + + +E + +A I ++ D+ +S+D A K +
Sbjct: 3710 DELGQLQAEIHKQQREIEKEKSNIESERAA----IIKIVEDLQHKIISLDRDAESLKLDR 3765
Query: 1543 TKVSNACDLLQ----EIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQLETS 1379
N ++L+ E+E EI + K+ Q R VEE ++ + K + + + +E +
Sbjct: 3766 EAFENEREVLKQMKTELERETDEIE-KIKLETQHDRQRVEEMTAQITKERDKINNLIEET 3824
Query: 1378 NTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE------- 1220
N D L+ ++ E S QS + + + +++LE +
Sbjct: 3825 NRKDM-VLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQKENTLAE 3883
Query: 1219 -----ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLN 1055
E K E + E+ + M + + L + L+ ++ K KE ++ +
Sbjct: 3884 IQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKD 3943
Query: 1054 HGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHA 875
R+E+ + EL ++ M + ++N +K L+ KD+ + E Q + + E +
Sbjct: 3944 ----RSELDLRQSELDKQQTNMNDIIETMKNERK--LLDKDKEEMEE-QKQEMEKERDNM 3996
Query: 874 NMSICSLSEKIQQIEEREKVL---LTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFI 704
+ SI SL E ++ ++ +++V+ +L ++Q A ++ +EE + ++ L+
Sbjct: 3997 DQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQNERQSLEKMT 4056
Query: 703 DNM--EASD-TNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNK 533
+ E D +L + + +EML V A + D ++ + E + +K
Sbjct: 4057 KALIKEREDLVHLAEYTKREKEMLDEMQV-----ANKSSMADLQREKRILEEMRENI-SK 4110
Query: 532 DTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
TEDI E + +++E+ KLQ++V+ QS + M K
Sbjct: 4111 QTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEK 4147
Score = 102 bits (253), Expect = 9e-19
Identities = 127/657 (19%), Positives = 292/657 (44%), Gaps = 30/657 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD + ++ K++ D+ ET+KN + LD +++ +++ E+ +++ +S
Sbjct: 6360 LDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDED 6419
Query: 2062 LKRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQANEEV 1892
LK +K +Q + E +++ E +K ELE + I +K+E + R +E + +EL + ++V
Sbjct: 6420 LKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDV 6479
Query: 1891 KVLS----KFRYQVLELEEYSQQLSADLSK-------VHEDYSAALRQLFDKKNEITCLQ 1745
L+ + + + E++ ++ ADL K + E+ S + +K++I +
Sbjct: 6480 AHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLRE 6539
Query: 1744 EVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSA 1565
+ +EQ + E +++ + + + A+ K + + KI L+ D L L +
Sbjct: 6540 DELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDRE--- 6596
Query: 1564 GVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQL 1388
F+ E ++ L+ + + +I++ET Q R VEE ++ ++ + + QL
Sbjct: 6597 -AFENEKEELKQMKTELEREADEIEKIKLET----QHERQRVEEMTADFMETMNNERKQL 6651
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKS 1208
+ + M E K + D D +Q LE E+ K
Sbjct: 6652 DKNKVMIE-----------EQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKL 6700
Query: 1207 KQM--------EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL---- 1064
+QM +E ++ E N + L YL +I + + L
Sbjct: 6701 EQMKIGLEREADEISKIKEETQNERQNLEKMAN---ALKEEREYLAEEIKRKNQVLDKIK 6757
Query: 1063 LLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKD--RAMIAEGQSKAFQL 890
+ N L A++ K L E + + D+EN +++ + +D + + E Q + ++
Sbjct: 6758 VANESTL-ADLQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEI 6816
Query: 889 ELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKD 710
+++ N+ SE+ I E++ ++T+L K D++ ++ +E + + + +LK
Sbjct: 6817 DMEKTNIE----SERAAMIREKQN-MMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKK 6871
Query: 709 FIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKD 530
+++++ +++ ++++ EA N ++M + +++ +Q +
Sbjct: 6872 DVEDLQQKLMSIERD---------SESLKLDKEAFEN--EKEAMKQMKTDLQIQA---DE 6917
Query: 529 TEDINTEIAHTSDK-DEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEK 362
E I E H + +E+ ++Q + E + +LV+ +K+ K +++ + +E+ EK
Sbjct: 6918 IEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIKK---KRDIIDESYTEIRKEK 6971
Score = 100 bits (250), Expect = 2e-18
Identities = 128/638 (20%), Positives = 274/638 (42%), Gaps = 31/638 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD + ++ K++ D+ ET+KN + LD +++ + +++ E+ + ++ +S
Sbjct: 5073 LDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 5132
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEE---SISVLKQELSSARLQIESLEKELNQANEEV 1892
LK +K +Q L + +S+ E +K ELE I +K+E+ + R +E + + L + E++
Sbjct: 5133 LKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL 5192
Query: 1891 KVLSKFRYQVL-ELEEYSQQLSAD-------LSKVHEDYSAALRQLFDKKNEITCLQEVI 1736
+K QVL E++ ++ AD L ++ E+ S + +KK + ++ +
Sbjct: 5193 AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDEL 5252
Query: 1735 EQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTL---SVDFSA 1565
Q + E +++ + + + + A+ K + + KI L+ D L L + +
Sbjct: 5253 RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEK 5312
Query: 1564 GVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQL 1388
V K+ T++ D +++I K+ Q R VEE ++ + K + + + +
Sbjct: 5313 EVLKQMKTELEREADEIEKI-----------KLETQHDRQRVEEMAAQIQKDRDEINNLI 5361
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE---- 1220
E +N D L+ ++ E S QS + + + +++LE +
Sbjct: 5362 EETNRKDM-VLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENT 5420
Query: 1219 --------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL 1064
E K E E+ + MN + + L + L+ ++ K KE +
Sbjct: 5421 LAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEII 5480
Query: 1063 LLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLEL 884
+ + QL S L + N M ++N +K+L KD+ + E Q + + E
Sbjct: 5481 MKDRSQLDLRQSELDKQQTNMNDIME----TMKNERKQL--DKDKEEMEE-QKQEMEKER 5533
Query: 883 KHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFI 704
+ + S SL E +++ K+ + ++ + +L +EIS KE ++
Sbjct: 5534 DNMDQSRKSLDED----QKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKR 5589
Query: 703 DNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAV----QTFPN 536
+E L + + + + + + + SM + E ++ + +
Sbjct: 5590 QRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENIS 5649
Query: 535 KDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
K E I+ E + +++E+ KLQ++V+ QS + M K
Sbjct: 5650 KLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEK 5687
Score = 95.5 bits (236), Expect = 9e-17
Identities = 119/641 (18%), Positives = 277/641 (43%), Gaps = 34/641 (5%)
Frame = -2
Query: 2242 LDAVRLDIQKEKN----ISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQS 2075
++ ++L+ Q E+ ++ D ET+ N + L+ ++ +++ E+ ++++ +S
Sbjct: 4652 IEKIKLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKS 4711
Query: 2074 EQMSLKRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQA 1904
+LK +K +Q + E +++ E +K ELE + I +K+E + R ++E + +EL +
Sbjct: 4712 LDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEADEIRKIKEETQNERQRLEKMTEELKKE 4771
Query: 1903 NE-----------EVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI 1757
E E K+L K + L Q+ ++L ++ E+ S +K +I
Sbjct: 4772 KESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKI 4831
Query: 1756 TCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSV 1577
++ +EQ + E +++ + + +N+ A+ K + + K+ L+ D+ L L
Sbjct: 4832 RLREDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRDLESLKLDR 4891
Query: 1576 DFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYL 1400
+ F+ E + L+ + +I++ET Q R VEE ++ + K + +
Sbjct: 4892 E----AFENEREVLKQIKTDLKRKAEEIEKIKLET----QHDRQRVEEMTAQIQKERDKI 4943
Query: 1399 KSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE 1220
+ +E +N D L+ E + +S + + ++NLE +
Sbjct: 4944 NNLIEETNRKDM-VLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQ 5002
Query: 1219 ------------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKY 1076
E K E++ + ++ + M + + L + L+ ++ K
Sbjct: 5003 RKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQQELEKE 5062
Query: 1075 KEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAF 896
KE ++ + QL S L + N M ++N +K+L K+ E Q +
Sbjct: 5063 KEIIMKDRSQLDLRQSELDKQQTNVNDIME----TMKNERKQLDKDKEE---TEEQKQEM 5115
Query: 895 QLELKHANMSICSLSEKIQQIEEREKVL---LTQLSTKDTDMQHLAAQLTLAQEEISSTK 725
+ E + S SL E ++ ++ +++VL ++L +++ A ++ +EEI + +
Sbjct: 5116 EKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNER 5175
Query: 724 EMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQT 545
+ L+ + ++ +L + ++L V + +++E I
Sbjct: 5176 QNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENI---- 5231
Query: 544 FPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
+K TED+ + + +++E+ +LQ+++ Q ++ K
Sbjct: 5232 --SKQTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEK 5270
Score = 95.1 bits (235), Expect = 1e-16
Identities = 127/646 (19%), Positives = 274/646 (42%), Gaps = 26/646 (4%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
D+Q+EK+I E+++E + L+ +D E++ S R+ E+ L E++ K+ +
Sbjct: 5633 DLQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQ----------KQQSK 5682
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSK---- 1877
+ ESER ++ E + ++ LK++ +Q++ + E + + K+L++
Sbjct: 5683 IDMEKTNIESERAAMIREKQNMMTELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVEN 5742
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVE---ERQR 1706
+ ++++LE S++L D + E+ A++Q+ K ++ + IE+ ++E +RQR
Sbjct: 5743 LQQKLIDLERDSKRLKLD-REAFENEKEAMKQM---KTDLQIQADEIEKIKLETQHDRQR 5798
Query: 1705 ECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNA 1526
+AA + +N L ++ + + + D+ + S+ + ++E +
Sbjct: 5799 VEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKT 5858
Query: 1525 CDLLQEIENFLREIRVETKVTIQEARHNVEEFS-SVVKHLEYLKSQLETSNTMDHDTLSS 1349
L +++ L + + T IQ+ R +VE+ + ++ + + +K Q E N
Sbjct: 5859 RSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMN--------- 5909
Query: 1348 THQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-ECKSKQMEEYKMLQAE 1172
+D+ + N +Q LE E E K ++ + Q+E
Sbjct: 5910 ----QKQDELDQLKTEIQN----------------LQQELEKEKEIIMKDRSQFDLRQSE 5949
Query: 1171 L-------NNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIE 1013
L N+ + M E + M + ++ K K D + L ++ +K++
Sbjct: 5950 LDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKDLKMMKLQ 6009
Query: 1012 ---LVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSE-- 848
E+ + +++E E+ K+ + ELK S L+E
Sbjct: 6010 KQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFTHLAEDT 6069
Query: 847 -KIQQIEEREKV----LLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASD 683
K Q+I ++ KV L+ L + ++++ + ++ E++ + KE L+ D +
Sbjct: 6070 KKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLREDEL---- 6125
Query: 682 TNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIA 503
LQ+ + Q + + +N E I K+ ED+ +I
Sbjct: 6126 WQLQAEIYKQQREIEKEKINIESERAAII--------------------KNVEDLQHKII 6165
Query: 502 HTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPE 365
+ D+D E +KL E ++ ++LKQ T+LE A + ++ E
Sbjct: 6166 -SLDRDSESLKLDR--EAFENEREVLKQMKTELEREADEIEKIKLE 6208
Score = 92.0 bits (227), Expect = 1e-15
Identities = 137/648 (21%), Positives = 278/648 (42%), Gaps = 30/648 (4%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIE-QKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++ +K+I E+ + + DL E K S D + ++ + E E + ++ K ++
Sbjct: 3343 EMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLTEKELLESDRKLLKKDVE 3402
Query: 2047 EAEQTLLEAESERESLKAE---LEESISVLKQELSSARLQIESLEKELNQANEEVKVLSK 1877
+Q LL ES+ ESLK + LE VLKQ + + + E +EK + E + + +
Sbjct: 3403 NLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEE 3462
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIE--QKEVEERQRE 1703
Q+ + EY Q+++ ++++ D +Q+ K++E+ L+ I+ Q+E+E+ +
Sbjct: 3463 MTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQELEKEKEI 3522
Query: 1702 CMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSV---------------DFS 1568
M SE D+ + L+K+ + I ++N+ QL DF
Sbjct: 3523 IMKDRSEL--DLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFD 3580
Query: 1567 AG--VFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKS 1394
G E+ + + +E +N L ++++E + E R EE + + LE +
Sbjct: 3581 QGRNSLDEDLKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTE 3640
Query: 1393 QLETSNTMDHDTLSSTHQGSMEDKASSQSSTGD----NDPKAXXXXXXXXXXXECRQNL- 1229
+L+ + S TH ED Q + N+ E R+N+
Sbjct: 3641 ELK------REKESFTHLA--EDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENIS 3692
Query: 1228 -ENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNH 1052
+ E+ K+K+ E ++ + EL + ++ + + +++ I+K EDL
Sbjct: 3693 KQTEDVKNKK-ENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKI 3751
Query: 1051 GQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHAN 872
L + SLK+ ++ F EN ++ L K + + +LE +H
Sbjct: 3752 ISLDRDAESLKL---DREAF--------ENEREVLKQMKTELERETDEIEKIKLETQHDR 3800
Query: 871 MSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNME 692
+ ++ +I + ++ L+ + + KD + + + I S K+ML+ N+E
Sbjct: 3801 QRVEEMTAQITKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLE 3860
Query: 691 ASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINT 512
+ +S +++E L Q N E Q E + K E+I
Sbjct: 3861 KT----RSELYKVKEDLEKQKENTLAEI-------QKEREDL---------EKMNENITI 3900
Query: 511 EIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTK-LELLAKKTSEMD 371
E+ ++E++ + Q +++ L++ +Q L+Q+ K E++ K SE+D
Sbjct: 3901 EMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELD 3948
Score = 92.0 bits (227), Expect = 1e-15
Identities = 127/649 (19%), Positives = 278/649 (42%), Gaps = 43/649 (6%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSL 2060
D + ++ K++ D+ ET+KN + LD +++ +++ E+ + ++ +S L
Sbjct: 5944 DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKDL 6003
Query: 2059 KRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQANE--- 1898
K +K +Q E +++ E +K ELE + I +K+E + R +E + +EL + E
Sbjct: 6004 KMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFT 6063
Query: 1897 --------EVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQE 1742
E ++L K + L Q+ ++L ++ E+ S + +KK + ++
Sbjct: 6064 HLAEDTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLRED 6123
Query: 1741 VIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTL---SVDF 1571
+ Q + E +++ + + + + A+ K + + KI L+ D L L + +
Sbjct: 6124 ELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFEN 6183
Query: 1570 SAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKS 1394
V K+ T++ D +++I K+ Q R VEE ++ + K + + +
Sbjct: 6184 EREVLKQMKTELEREADEIEKI-----------KLETQHDRQRVEEMTAQIQKDRDKINN 6232
Query: 1393 QLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-- 1220
+E +N D L+ ++ + S QS + + + +++LE +
Sbjct: 6233 LIEETNRKDM-VLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKE 6291
Query: 1219 ----------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKE 1070
E K E E+ + MN + + L + L+ ++ K KE
Sbjct: 6292 NTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKE 6351
Query: 1069 DLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQL 890
++ QL S L + N M ++N +K+L KD+ + E Q + +
Sbjct: 6352 IIMKARSQLDRRQSELDKQQTNMNDIME----TMKNERKQL--DKDKEEMEE-QKQEMEK 6404
Query: 889 ELKHANMSICSLSEKIQQIEEREKVL---LTQLSTKDTDMQHLAAQLTLAQEEISSTKEM 719
E + + S SL E ++ ++ +++V+ +L +++ A + +EE + +++
Sbjct: 6405 ERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQI 6464
Query: 718 LKDFIDNME---------ASDTNLQSHFNQIQEM-LLNQNVNYPLEATVNIGFDQSMDEA 569
L+ + ++ A DT + N + EM + N++ L+ +++E
Sbjct: 6465 LEKMAEELKKERKDVAHLAEDTKREK--NSLDEMKVANESSMADLQKE-----KSNLEEM 6517
Query: 568 VSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
I +K TEDI E +++E+ +LQ+++ QS ++ K
Sbjct: 6518 KENI------SKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEK 6560
Score = 84.0 bits (206), Expect = 3e-13
Identities = 137/676 (20%), Positives = 281/676 (41%), Gaps = 48/676 (7%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDL-DIEQKLSTDRQSEIYSLS-AELER---ITQ 2078
L R DI+K E K ++ + +L D + +L DR + ++ EL+R + +
Sbjct: 9214 LQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRE 9273
Query: 2077 SEQMSLKRLKEAEQTLL---EAESERESLK-------------AELEESISVLKQELSSA 1946
+E + K L++ EQ + + E++ E+L+ A+ E++ +Q+L
Sbjct: 9274 TEDLERKILQQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLL 9333
Query: 1945 RLQIESLEKELNQA--NEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFD 1772
+ ++S E EL EE K L + + + E + ++S ++ +Y + +L
Sbjct: 9334 QGALQSQESELENRVFMEEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQR 9393
Query: 1771 KKNEITCLQEVIEQKEVE--------ERQRECMLAASERSNDINVNALEKKLSA---YEG 1625
+K ++ + IEQ++ + ERQ E + D NALEK S +
Sbjct: 9394 EKEQLEISKNQIEQEKKDLQNMKSNLERQLESLRHEKANVED-EKNALEKMRSESKEIQN 9452
Query: 1624 KIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARH 1445
IR+ D+ + ++ +EE+ ++ + ++++++ L++ R + ++ +
Sbjct: 9453 AIRKEREDLENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINN 9512
Query: 1444 NVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXX 1265
+EE + + K ++E + D E + D K
Sbjct: 9513 KMEELLQMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQE--- 9569
Query: 1264 XXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDI 1085
+ E K + +E K L E+ + + EM + +G +
Sbjct: 9570 ------------KEREIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLL 9617
Query: 1084 LKYKEDLLLNHGQLRAEMSSL---KIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAE 914
K K++L +L +M L K E E+ + +E+++KE I K++ + +
Sbjct: 9618 EKEKQELKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEK 9677
Query: 913 GQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTK-DTDMQHLAAQLTLAQEE- 740
+ QL++ L+++ ++ ++EK L Q + + Q L T EE
Sbjct: 9678 SNIEEMQLKIFKQQR----LNDQTREENKKEKESLEQQRFETEQQKQMLEISTTKMMEEK 9733
Query: 739 -----ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMD 575
+S + KD ++ + A TN + H + + L+ + +E I D+
Sbjct: 9734 NEMADLSRELQKAKDELEKI-AYKTNKERHEVEQMQAELHSQIQ-AIEQQGQIMQDKQNH 9791
Query: 574 EAVSEIAVQTFPNK---DTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTK- 407
E+++Q + + E H ++ EE K Q +E +++ +++ KQ+N K
Sbjct: 9792 LEEKELSIQRKEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQKNNKD 9851
Query: 406 LELLAKKTSEMDPEKY 359
ELL K SE++ EKY
Sbjct: 9852 FELLEKIRSELENEKY 9867
Score = 80.1 bits (196), Expect = 4e-12
Identities = 118/630 (18%), Positives = 261/630 (41%), Gaps = 10/630 (1%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
D+Q+EK I E+++E + D++ E++ S R+ E+ L E++ K+ E
Sbjct: 4093 DLQREKRILEEMRENISKQTEDIENEKEKSKLREDELKKLQTEVQ----------KQQSE 4142
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESL--EKEL--NQANEEVKVLSK 1877
+ ESER + E + ++ LK++ +Q++ + EKEL N +N K +
Sbjct: 4143 IDMEKTNIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMED 4202
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVE---ERQR 1706
+ +++ +E S+ L D E + L K ++ + IE+ ++E +RQR
Sbjct: 4203 LKQKLMSIERDSESLKLD----REAFGNEKEVLKQMKTDLQIQADEIEKIKLETQHDRQR 4258
Query: 1705 ECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNA 1526
A + + +N L + + + + ++ D+ + S+ + ++E +
Sbjct: 4259 VEEKTAQIQKDRDEINNLIVETNRKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLEKT 4318
Query: 1525 -CDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSS 1349
+L + EN + +E K I++ + N+ +KH E Q + + +
Sbjct: 4319 RSELARAKENLETQREIERK-DIEKMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQN 4377
Query: 1348 THQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAEL 1169
Q ++K + D + + + ++NE KQ+++ K E
Sbjct: 4378 LQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNER---KQLDKDK---EET 4431
Query: 1168 NNWLSCMNAEMGKFLCLCNSMVYLEGDI--LKYKEDLLLNHGQLRAEMSSLKIELVEKNG 995
M E F S L+ D+ +K ++ ++ + ++++ +KIEL +
Sbjct: 4432 EEQKQEMEKEKHDF---DQSRKSLDEDLKMMKLQKQVI---EEEKSKLKQMKIELEREAD 4485
Query: 994 FMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKV 815
++ V++E ++ I E ++A + E + + ++ + +++ +
Sbjct: 4486 -------EIRKVKEET---QNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANES 4535
Query: 814 LLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLN 635
L + + +++Q + ++ E++ + KE ++ E LQ+ ++ Q
Sbjct: 4536 TLADILRERSNLQEMRENISKQTEDVENKKEKIR----LREEKLKQLQAEIHKQQSETEK 4591
Query: 634 QNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQV 455
+ N E I KD ED+ ++I + D+D E +KL
Sbjct: 4592 EKSNIERERAAII--------------------KDVEDLQSKII-SLDRDAESLKLDR-- 4628
Query: 454 ENLQSLVQMLKQQNTKLELLAKKTSEMDPE 365
E ++ + LKQ T+LE A + ++ E
Sbjct: 4629 EAFENEKEELKQMKTELEREADEIEKIKLE 4658
Score = 79.7 bits (195), Expect = 5e-12
Identities = 122/685 (17%), Positives = 295/685 (43%), Gaps = 64/685 (9%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
+I+KEK KE + + + +I + T+R+ E+Y + +ELER+ K+L +
Sbjct: 11007 EIKKEKE-----KENEEEEEEEEEIRVIVETERK-ELYQIKSELERVRSEIDHEQKKLND 11060
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSA--RLQIESLEKELNQANEEV--KVLSK 1877
+ + + + + E +K+E+ + +++E S ++Q +LEK + ++E+ K++ +
Sbjct: 11061 YMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVE 11120
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECM 1697
Q +++ ++L + K+ ++ + ++ +NE +++V E+ +++RE +
Sbjct: 11121 VEEQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKKVDEE---IKKERETL 11177
Query: 1696 LAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDL 1517
R +I++ +++L + + +R + D+ +++ ++ E+ + N DL
Sbjct: 11178 -----REMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDIN-------EQKLHLKNQRDL 11225
Query: 1516 LQEIENFLREIRVETKVTIQEARHNVEEFSSVV--KHLEYLKSQLETSNTMDHDTLSSTH 1343
L+ + R E + + + ++EF + V + + K ++E +T +
Sbjct: 11226 LE-------QEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARII 11278
Query: 1342 QGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECK---SKQMEEYKMLQAE 1172
+ M+ KA Q + + + + EE + + EE +++E
Sbjct: 11279 E--MKTKAELQEIMQEKEEE------------------DEEEMRVIVEMEREELNQIKSE 11318
Query: 1171 LNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSL---------- 1022
L S ++ E K + + D+ K K +++ Q+ E S L
Sbjct: 11319 LKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLE 11378
Query: 1021 KIELVEKNGFMGYAVLDVENVQKELLIWK-----DRAMIAEGQSKAFQ--LELKHANMSI 863
+ ++ + ++ VE +K++ + K +R IA+ Q Q +L++ N I
Sbjct: 11379 RHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERI 11438
Query: 862 CSLSEKI---------------QQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISST 728
+ E+I ++ EE V+ K D++ ++ + +++ +
Sbjct: 11439 KEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDVNKQNQDLMNQ 11498
Query: 727 KEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEA---VSEI 557
+++LK + + T LQ ++ + Q + +S++E + E+
Sbjct: 11499 RDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEM 11558
Query: 556 AVQTFP-----NKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLV-----------QML 425
+T P K+ E+ A K EE+ +++SQ+E ++S + +M+
Sbjct: 11559 KTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMI 11618
Query: 424 KQQNTKLEL----LAKKTSEMDPEK 362
+Q+ LE + K+ +M+ E+
Sbjct: 11619 EQEKEDLEKMKSEIMKQRQQMEEER 11643
Score = 78.6 bits (192), Expect = 1e-11
Identities = 129/680 (18%), Positives = 300/680 (44%), Gaps = 61/680 (8%)
Frame = -2
Query: 2227 LDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++IQKE+ I E LK + + DL+ E+ +++I SLS +L+ ++ E + R +
Sbjct: 2863 VEIQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI-SLSEDLKEQSEREGIDNTRTR 2921
Query: 2047 ----------------------EAEQTLLEAESER-ESLKAELEESISVLKQELSSARLQ 1937
E ++ ++E E ++ E +KAEL++ K EL + R
Sbjct: 2922 IKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNERQN 2981
Query: 1936 IESLEKELNQANEEVKVLSK--FRYQV----LELEEYSQQLSADLSKVHEDYSAALRQLF 1775
+E +L + E V+ L++ R QV +++E Q+ + + +K ++ L +L
Sbjct: 2982 LEEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQE--RVLIELK 3039
Query: 1774 DKKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVS 1595
+I +E +E + +EER++ + A ++ + L++ +S + I N
Sbjct: 3040 KTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDI---VNKTE 3096
Query: 1594 QLTLS----VDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFS 1427
QL L A +++++ +N ++ E + L + E +E +E S
Sbjct: 3097 QLRLREVELEQLQALIYRQQDEIEANRKAIINE-KYRLEGQKTEIDRLQREVNQMMEYAS 3155
Query: 1426 SVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSS-TGDNDPKAXXXXXXXXXX 1250
+LE KS++ + D + +G +E++ ++ + D K
Sbjct: 3156 KDRANLEKEKSEM-IAQKHQMDIELNKERGLIEERTQMLNTYEKEMDQKRTALEVEMKEL 3214
Query: 1249 XECRQNLENEECKSKQM--------EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLE 1094
+Q ++ E+ K +QM ++ K L+ + N + + + +L
Sbjct: 3215 KYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLAHLA 3274
Query: 1093 GDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAE 914
D + +++ + H A++ K L + M +++ +K++++ +D+ +
Sbjct: 3275 EDTKRKDDEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQQMQ 3334
Query: 913 GQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEIS 734
+ Q E+ SI + + + ++ + L+T+L+ + D++ ++ +E +
Sbjct: 3335 AEINRQQTEM-DTKKSI--IENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLTEKELLE 3391
Query: 733 STKEMLKDFIDNMEASDTNLQS---HFNQIQEMLLNQ---------NVNYPLEATVNIGF 590
S +++LK ++N++ ++S Q +E+L N+ ++ E I
Sbjct: 3392 SDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKL 3451
Query: 589 D-----QSMDEAVSEIAV-QTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQM 428
+ Q ++E ++I + + K ++I EI +++++ + Q +++ L++ +Q
Sbjct: 3452 ETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQN 3511
Query: 427 LKQQNTK-LELLAKKTSEMD 371
L+Q+ K E++ K SE+D
Sbjct: 3512 LQQELEKEKEIIMKDRSELD 3531
Score = 78.6 bits (192), Expect = 1e-11
Identities = 131/650 (20%), Positives = 261/650 (40%), Gaps = 30/650 (4%)
Frame = -2
Query: 2245 TLDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQM 2066
T+ R + K+K +E+ K+ ++ + D D +K S
Sbjct: 4416 TMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRK---------------------SLDE 4454
Query: 2065 SLKRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQANEE 1895
LK +K +Q + E +S+ + +K ELE + I +K+E + R E + + L + E+
Sbjct: 4455 DLKMMKLQKQVIEEEKSKLKQMKIELEREADEIRKVKEETQNERQIFEKMTEALKKERED 4514
Query: 1894 VKVLSKFRYQVL-ELEEYSQQLSAD-------LSKVHEDYSAALRQLFDKKNEITCLQEV 1739
+ +K + QVL E++ ++ AD L ++ E+ S + +KK +I +E
Sbjct: 4515 LSEDAKRKNQVLDEMKVANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLREEK 4574
Query: 1738 IEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGV 1559
++Q + E +++ + + + A+ K + + KI L+ D L L +
Sbjct: 4575 LKQLQAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDRE----A 4630
Query: 1558 FKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETS 1379
F+ E ++ L+ + + +I++ET Q R VEE ++ +ET
Sbjct: 4631 FENEKEELKQMKTELEREADEIEKIKLET----QHERQRVEEMTA---------DFMETM 4677
Query: 1378 NTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQM 1199
N + L+ + E K + D D +Q +E E+ K +QM
Sbjct: 4678 NN-ERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQM 4736
Query: 1198 --------EEYKMLQAELNN---WLSCMNAEMGKFLCLCNSMVYLEGDI---LKYKEDLL 1061
+E + ++ E N L M E+ K S +L D K + +
Sbjct: 4737 KIELEKEADEIRKIKEETQNERQRLEKMTEELKKEK---ESFTHLAEDTKTEKKILDKMK 4793
Query: 1060 LNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELK 881
+ + L A++ K L E + D E ++++ + +D + + Q E+K
Sbjct: 4794 VANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQLQAEIHKQQGEIK 4853
Query: 880 HANMSICSLSEKIQQIEEREKVLLTQLSTKDT-DMQHLAAQLTLAQEEISSTKEMLKDFI 704
EK ER ++ KD D+QH L E + +E ++
Sbjct: 4854 ---------MEKSNNESERAAII------KDVKDLQHKMFSLDRDLESLKLDREAFENER 4898
Query: 703 DNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTE 524
+ ++ T+L+ +I+++ L + Q ++E ++I K+ +
Sbjct: 4899 EVLKQIKTDLKRKAEEIEKIKLETQHD-----------RQRVEEMTAQI------QKERD 4941
Query: 523 DINTEIAHTSDKD----EEVIKLQSQVENLQSLVQMLKQQNTKLELLAKK 386
IN I T+ KD E +++ +++ ++S ML+++ LE K
Sbjct: 4942 KINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSK 4991
Score = 76.3 bits (186), Expect = 5e-11
Identities = 150/706 (21%), Positives = 304/706 (43%), Gaps = 71/706 (10%)
Frame = -2
Query: 2233 VRLDIQKEKNISEDLKET-------VKNLQSDLDIEQKLSTD--------------RQSE 2117
+++++QK+KN E+L+ T V+N + LD +QK D +SE
Sbjct: 14074 LQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSE 14133
Query: 2116 IYSLSAELERITQSEQMSLKRLKEAEQTLLE-----AESERESLKAE------LEESISV 1970
+ LS L Q EQ L+RL E E+ +E ESE++S++ E L+E + V
Sbjct: 14134 LNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIESEKQSIERERAELKRLKEEVEV 14193
Query: 1969 ------LKQELSSARLQIESLEKELNQANEEVKVL-SKFRYQVLELEEYSQQLSADLSKV 1811
L+Q+ + + + E LE E + EE+ L + + + EL+ ++++ A K
Sbjct: 14194 QHERTLLQQDKNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEA---KR 14250
Query: 1810 HEDYSAALRQLFD----KKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKK 1643
E+ L + + K E L+E I +K+ + ++ L + R + +L++
Sbjct: 14251 QEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQ-TSLDEI 14309
Query: 1642 LSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREI-RVET-- 1472
E + R LE V+ + V K E T S ++ + N ++E+ R++T
Sbjct: 14310 TKTDERRQRALEETVA----TTAKQPIVIKLEDTLTSEVQEMRDHLNNEIKELARMKTIM 14365
Query: 1471 ---KVTIQEARHNV----EEFSSVVKHLEYLKSQLE---TSNTMDHDTLSSTHQGSMEDK 1322
K +++A+ ++ EEF ++ KS+ E T D + LS+T +
Sbjct: 14366 KMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLD---KKN 14422
Query: 1321 ASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNA 1142
+++T K + ++N+ENE + KQ+E+ + +Q + + ++
Sbjct: 14423 KEIENNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQIEQEREIQRKAD--VTSTEK 14480
Query: 1141 EMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVE- 965
EM Y E + YK +L + +++ + S +EL + + + +
Sbjct: 14481 EM-----------YTEK--VTYKTELEDSKEKIKPDRDS-TLELTDTDSAKTDGEREAQT 14526
Query: 964 ---NVQKELLIWKDRAMIAEGQSKAFQ------LELKHANMSICSLSEKIQQIEEREKVL 812
VQ L + D E + LEL A + L E+ + EE + V+
Sbjct: 14527 LETKVQDVLQLTDDTTQDQEELHDEMENKMKIILELNKAKKDLQKLKEECRSAEEEKSVI 14586
Query: 811 LTQLSTKDTDMQHLAAQ-LTLAQE--EISSTKEMLKDFIDNMEASDTNLQSHFNQIQEML 641
+ L + ++ + ++ L+L QE ++ K ++ M+ ++ + + ++
Sbjct: 14587 MESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWE--TDVQ 14644
Query: 640 LNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKD-EEVIKLQ 464
+ Q P+E T +I +S +E ++ Q K + + +E+ D + E+V +++
Sbjct: 14645 IQQEGQEPIETTGHI-TKKSEEEISAKKTKQPIVTKLEDTLTSEVQEMRDMEIEDVARMK 14703
Query: 463 SQVENLQSLVQMLKQQ-NTKLELLAKKTSEMDPEKYFHFEELCQSL 329
+ ++ + ++ K ++E + E EK + E L Q L
Sbjct: 14704 TMMKMEKDQLEQAKSDIQRQMEEFERNMEETLKEKSRNEETLLQLL 14749
Score = 75.9 bits (185), Expect = 7e-11
Identities = 131/629 (20%), Positives = 268/629 (42%), Gaps = 25/629 (3%)
Frame = -2
Query: 2227 LDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++IQKE+ I E LK + + DL+ E+ +++I SL ELE ++ E + R++
Sbjct: 2469 VEIQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI-SLREELEEQSEKEGIDKTRVR 2527
Query: 2047 EAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRY 1868
+Q + E E R ++ ELE + + KQ + R +IE ++ EL +E K K R
Sbjct: 2528 -IKQEMDELEQTRLNVVKELENN-ELQKQIIEDERDKIEQIKAEL---QKEAKDTEKQRQ 2582
Query: 1867 QVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIE------QKE------ 1724
+ ++++ L +D + ++ D++ + L++ +E +KE
Sbjct: 2583 DIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDLKK 2642
Query: 1723 --VEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
E + E L + R ++I + ++K+ E +L+ +S+ ++ F++
Sbjct: 2643 TNTEMKDLEKQLESQNRQHEIQLAEIQKEREILE----QLKLTLSKQKEDLEKERDCFEK 2698
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFS-SVVKHLEYLKSQLETSNT 1373
E +S +L ++ E RE +T+V I++ +++ +VVK LE +N
Sbjct: 2699 EKADISLREELQEQSE---REGIGKTRVRIKKEMDELKQTRLNVVKELE--------NNE 2747
Query: 1372 MDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEE 1193
+ + + KA Q D + + E L+NE+ K +
Sbjct: 2748 LQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEK-KDIETST 2806
Query: 1192 YKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIE 1013
++ E N + E + +++ D+ K K ++ QL +++ +I+
Sbjct: 2807 DRIRDEEANLEVQKQRLESDR-----DTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQ 2861
Query: 1012 LVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELK--HANMSICSLSEKIQ 839
LVE +QKE I + + Q + + E + SLSE ++
Sbjct: 2862 LVE--------------IQKEREILEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLK 2907
Query: 838 QIEEREKV--LLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSH 665
+ ERE + T++ + +++ L QE K++++D D +E L+
Sbjct: 2908 EQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKE 2967
Query: 664 FNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEI---AHTS 494
+ + L N+ N EA + D+ E+++E + + I TE+ A+ S
Sbjct: 2968 AEKTKLELQNERQNLE-EAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANES 3026
Query: 493 DK---DEEVIKLQSQVENLQSLVQMLKQQ 416
+K + +I+L+ V ++ + L+ Q
Sbjct: 3027 NKQMQERVLIELKKTVTDIAGAKEDLENQ 3055
Score = 75.9 bits (185), Expect = 7e-11
Identities = 137/684 (20%), Positives = 276/684 (40%), Gaps = 75/684 (10%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L ++ ++ KEK E++K+ VK + ++ E++ + + + I +
Sbjct: 9137 LQQMKNELNKEKEQVEEMKQMVKTERVKIEQEKE----------EMRKQTQEIEDGHEKL 9186
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVL 1883
K+ + A++ L +A SE + LK +L + + +Q++ ++E+ ++ L++ + E+
Sbjct: 9187 QKKTEIADKLLQDANSESDRLK-DLSMKLQMQRQDIEKTNTEMETKKRSLDRMSREL--- 9242
Query: 1882 SKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRE 1703
Q L + Y + L K+ E+ E +E+K +++R+++
Sbjct: 9243 --------------QDDKIRLKNDRDAYEKDMTHLELKREELVRETEDLERKILQQREQD 9288
Query: 1702 CMLAASERSNDINVNALE-------KKLSAYEGKIRRLENDVSQLTL--------SVDFS 1568
M ++R + ALE KK + + ++ + ++ +L L +
Sbjct: 9289 EM---AKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQESELE 9345
Query: 1567 AGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQL 1388
VF EE + A +E L E+ E R +EE + LE K+Q+
Sbjct: 9346 NRVFMEEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQREKEQLEISKNQI 9405
Query: 1387 ETSNTMDHDTLSSTHQGSME----DKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLEN- 1223
E D + S + +E +KA+ + + + R++LEN
Sbjct: 9406 E-QEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENC 9464
Query: 1222 ---EECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNH 1052
E + K+MEE + +++E+ K ++ E I E+LL
Sbjct: 9465 WVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSR---ENIESREEKINNKMEELL--- 9518
Query: 1051 GQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDR------AMIAEGQ------ 908
Q++ EM K E+ +++ + A +D+EN + E+ +D+ I E +
Sbjct: 9519 -QMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQ 9577
Query: 907 --------SKAFQLELKHANMSICSLSEKIQQIE------EREKVLLTQLSTK-DTDMQH 773
S+ +L++K M + + + Q+IE E+EK L Q + + M
Sbjct: 9578 LDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMD 9637
Query: 772 LAAQLTLAQEE---ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLL----NQNVN--- 623
L + +EE + + K L+D E L + I+EM L Q +N
Sbjct: 9638 LTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQT 9697
Query: 622 -----YPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTE--DINTEIAHTSDKDEEVI--- 473
E+ F+ + + EI+ + E D++ E+ D+ E++
Sbjct: 9698 REENKKEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDELEKIAYKT 9757
Query: 472 -KLQSQVENLQ----SLVQMLKQQ 416
K + +VE +Q S +Q ++QQ
Sbjct: 9758 NKERHEVEQMQAELHSQIQAIEQQ 9781
Score = 75.1 bits (183), Expect = 1e-10
Identities = 131/671 (19%), Positives = 280/671 (41%), Gaps = 33/671 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD ++ ++Q E E++K + +++++ EQ+ + I +LE + +
Sbjct: 10108 LDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGDLEIMRADYE-- 10165
Query: 2062 LKRLKEAEQTLLEAESERESL---KAELEESISVLKQELSSARLQIESLEKELNQANEEV 1892
K+ ++ E+ +EA+ ER+ L K+ELE+ + + E +EKE N
Sbjct: 10166 -KQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKERNDLE--- 10221
Query: 1891 KVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQ--KEVE 1718
K+ S+ Q ++E+ +L + + + + K++I +E++E+ EVE
Sbjct: 10222 KMKSELMTQRQQMEDERSELDQKIKEANTE-----------KDKIEKNKEIVERLMAEVE 10270
Query: 1717 ERQRECML----AASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
E++ + L A ER N ++ L L+ E +++ + + E
Sbjct: 10271 EQRNDFKLKKEELALERQNIVDEKYL---LAQCETELQNKSEQIRNM------------E 10315
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTM 1370
E+ K N + L+E E L+ + E K I+E E+ + + K +L+
Sbjct: 10316 EAVK--NERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKK-- 10371
Query: 1369 DHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEY 1190
DTL + Q + D + R+ E + K+MEE
Sbjct: 10372 --DTLEQEREEINHKWTQFQQRIDEFDAQV-------------RKQKEEDLTNQKKMEEE 10416
Query: 1189 KMLQAELNNWLSCMNA----EMGKFLCLCNSMVYLEGDILKYKED---LLLNHGQLRAEM 1031
+ E+N + M E + + L+ I+K KE + + R ++
Sbjct: 10417 RKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAMTIKLKMEREDL 10476
Query: 1030 SSLKIELVEKNGFMGYAVLDVENVQKEL-----LIWKDRAMIAEGQSKAFQLELKHANMS 866
+K ELV + +V++ QK+L +I +++ + + +S+ + +
Sbjct: 10477 DQIKSELVREK-------TEVDHEQKKLNDDIKMIEQEKEDLEKMKSE-IMTQKQEMEKE 10528
Query: 865 ICSLSEKIQQIE------EREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFI 704
L KIQQ + E+ K ++ +L + + +H ++ L +EE+ ++ + D
Sbjct: 10529 RSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRH---EIQLQKEELDIERQKIADEQ 10585
Query: 703 DNMEASDTNLQSHFNQIQEMLLNQNVNYPLEA--TVNIGFDQSMDEAVSEIAVQTFPNKD 530
D + + + LQ+ +I+ +N+ + E + ++ +E S +D
Sbjct: 10586 DLLIQNKSELQNENERIRN--INEVIKKERETLKEMEAHLEKEKEEMKSITEETRRQKED 10643
Query: 529 TEDINTEIAHTSDKDEEVIK----LQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEK 362
E ++T+I +++++++K L+ + E++ L+Q+ + + K E D K
Sbjct: 10644 LEKMSTDI---KEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQVSKQKEEDLTK 10700
Query: 361 YFHFEELCQSL 329
+E +SL
Sbjct: 10701 QKEMKEERKSL 10711
Score = 75.1 bits (183), Expect = 1e-10
Identities = 132/702 (18%), Positives = 287/702 (40%), Gaps = 68/702 (9%)
Frame = -2
Query: 2245 TLDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLST-------DRQSEIYSLSAELER 2087
TL + ++KEK + + E + + DL +K+ST D +S+ L E E
Sbjct: 12007 TLKEMEAYLEKEKEEMKSITEETRRQKEDL---EKMSTHINEQKQDLRSQRDLLEQEREE 12063
Query: 2086 ITQSEQMSLKRL--------KEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIE 1931
I + +R+ K+ E+ L + + +E K+ E ++L+ + + + E
Sbjct: 12064 INHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMK---TKAEPE 12120
Query: 1930 SLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITC 1751
++KE + EE ++ K + E+E Q+ + L +V + ++L D K I
Sbjct: 12121 EIKKEKEKEEEEQEMRVKVEMERKEIE----QIKSQLERVRSEMDHEQKKLNDDKKMIEQ 12176
Query: 1750 LQEVIE--QKEVEERQRECMLAASERSNDINVNALEK-KLSAYEGKIRRLENDVSQLTLS 1580
+E +E + E+ +++++ SE I LEK + + + +L +V +
Sbjct: 12177 EKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHE 12236
Query: 1579 VDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYL 1400
+ F E K+++ DLL ++ K+ Q ++E +K
Sbjct: 12237 IQFQKEELDIERQKIADEQDLL-----------IQNKIEQQNENERIKEMDEEIKKERET 12285
Query: 1399 KSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE 1220
++E + + + + S + + K + + D + + +Q+L N+
Sbjct: 12286 LKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQ--------------KQDLMNQ 12331
Query: 1219 ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGD-----------ILKYK 1073
KQ E E+N+ L+ + + +F N +V + + +K
Sbjct: 12332 RDLLKQERE------EMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEY 12385
Query: 1072 EDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQ 893
E ++ + R E+ ++++ ++N + +E +K+ K+R E Q +A
Sbjct: 12386 ESIIEETNRKRTELEEIEVDQSQQNKNVETMKDLLEKERKD--TEKER---EELQKQADD 12440
Query: 892 LELK------HANMSICSLSEKIQQIEEREKVLLTQ---LSTKDTDMQHLAAQLTLAQEE 740
LE++ MS SL E+ + +E++ +L Q L + DM +L Q+E
Sbjct: 12441 LEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKE 12500
Query: 739 ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSE 560
I + K +++ +E + +++E L N V + +++ + + E
Sbjct: 12501 IQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKHQQQ-IEE 12559
Query: 559 IAVQTFPNKDTED----------------------INTEIAHTS---DKDEEVIKLQSQ- 458
+ V+T +D D + E+ T D EE +KL+ Q
Sbjct: 12560 MRVKTKMERDELDQLMAKMLMDRKENERSKDMIGLLKKEMEQTKFNLDAQEEELKLEKQK 12619
Query: 457 VENLQSLVQM----LKQQNTKLELLAKKTSEMDPEKYFHFEE 344
++N + ++M +K++ ++++ L ++ E D + + +E
Sbjct: 12620 IQNEKKDLEMFKAEIKREASEVKTLKEQQLEKDTKAFEALKE 12661
Score = 75.1 bits (183), Expect = 1e-10
Identities = 125/644 (19%), Positives = 282/644 (43%), Gaps = 28/644 (4%)
Frame = -2
Query: 2218 QKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELE-RITQSEQMSLKRLKEA 2042
+KEK+ +++ ++++S ++ +L T+ ++I +++EL+ R + E + K+ KE
Sbjct: 13524 RKEKHAEAEIQRQFEDIES---VKVRLVTE-SNQIDKMNSELKTRSEELENLIKKQQKEF 13579
Query: 2041 EQTLLEAESERESLK---AELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFR 1871
E E + ER++L+ AELE + LK ++ + L+KE N+ E +L + +
Sbjct: 13580 ETKENEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREK 13639
Query: 1870 YQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-----TCLQEV-IEQKEVEERQ 1709
++ + + QQ ++ + + + + L +NE+ + L + +E+ E+++ +
Sbjct: 13640 SELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLK 13699
Query: 1708 RECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSN 1529
E + + + S + L++ E K +L+N + ++ + + +E+ +
Sbjct: 13700 TE--IQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMD---KLSIQREKDSLEEI 13754
Query: 1528 ACDLLQEIENFLREIRVETKVT--IQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTL 1355
DL ++ E E+R ++T I + +++ + L +++ +E + L
Sbjct: 13755 KADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQAKI----L 13810
Query: 1354 SSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSK-QMEEYKMLQ 1178
S Q +K + S +ND R++LE + ++ ++E + +
Sbjct: 13811 ESDVQLLQTEKEILEKSKTEND--------------LLREDLEKQRKRNDLTLQELRKEK 13856
Query: 1177 AELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKN 998
L ++ + E L N V L+ LK KE L + R EM L+++L +
Sbjct: 13857 MALEQMITDITKEKDAVASLQNE-VSLKQHELKNKETEL---DEQRKEMDDLRMQLEMRQ 13912
Query: 997 GFMG-----YAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELK----HANMSICSLSEK 845
V VEN++ + + ++ E + + Q +K N+ S ++
Sbjct: 13913 NSTNKQQQEVDVFIVENMKMRNDLESMKTLLDE-ERRQLQDNIKTFEDQKNVLHPSKTDA 13971
Query: 844 IQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSH 665
+QQ +E EK T + T+ ++ ++ + +EI +KE L+ +E +
Sbjct: 13972 VQQTDELEK-FTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGK 14030
Query: 664 FNQIQEMLLNQNVNYPLEATVNIGFD--QSMDEAVSEIAVQTFPNKDTEDINTEIAHTSD 491
QI+ + L A + G D +++ + ++A++ K ++ + +
Sbjct: 14031 RAQIESL-------EQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKN 14083
Query: 490 KDEEVIKL----QSQVENLQSLVQMLKQQNTKLELLAKKTSEMD 371
+ EE+ + QVEN + + + KQQ +++ SE D
Sbjct: 14084 ELEELRNTIEAEKHQVENRK--IMLDKQQKEVEDIMTVIKSERD 14125
Score = 72.8 bits (177), Expect = 6e-10
Identities = 145/702 (20%), Positives = 296/702 (42%), Gaps = 82/702 (11%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSE--------- 2072
+IQKE+ I E LK T+ + DL+ E+ +++I SL EL+ ++ E
Sbjct: 2667 EIQKEREILEQLKLTLSKQKEDLEKERDCFEKEKADI-SLREELQEQSEREGIGKTRVRI 2725
Query: 2071 --------QMSLKRLKEAEQTLLE---AESER---ESLKAELE---ESISVLKQELSSAR 1943
Q L +KE E L+ E ER E +KAEL+ E ++++ R
Sbjct: 2726 KKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDR 2785
Query: 1942 LQIESLEKELNQANEEVKV-LSKFRYQVLELEEYSQQLSAD-----------------LS 1817
E + +L ++++ + R + LE Q+L +D +
Sbjct: 2786 RNNEEMVIKLQNEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKERFDLEKTKTEMG 2845
Query: 1816 KVHEDYSAALRQLFDKKNEITCLQEVIE--------QKEVEERQRECMLAASERSNDINV 1661
+ + + +RQ + EI +E++E QKE E++R+C + DI++
Sbjct: 2846 NLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCF---EKEKADISL 2902
Query: 1660 NALEKKLSAYEGKIRRLENDVSQLTLSVD----FSAGVFKEESTK------VSNACDLLQ 1511
+ K+ S EG ++N +++ +D + KE+ + + D ++
Sbjct: 2903 SEDLKEQSEREG----IDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIE 2958
Query: 1510 EIENFLREIRVETKVTIQEARHNVEEFSSVVK----HLEYLKSQLETSNTMDHDTLSSTH 1343
+I+ L++ +TK+ +Q R N+EE + +K ++E L +L + + T
Sbjct: 2959 QIKAELKKEAEKTKLELQNERQNLEEAGTKLKKDRENVESLAEELGRKQVVLENMQIET- 3017
Query: 1342 QGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNN 1163
M+ KA ++S+ + +++LEN+ + + E+ K+ QAE+
Sbjct: 3018 --EMQRKA-NESNKQMQERVLIELKKTVTDIAGAKEDLENQLLEER--EKNKVKQAEI-- 3070
Query: 1162 WLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQL----------RAEMSSLKIE 1013
AE L + + DI+ E L L +L + E+ + +
Sbjct: 3071 -----QAEKDMLYLLKQGISEQQVDIVNKTEQLRLREVELEQLQALIYRQQDEIEANRKA 3125
Query: 1012 LVEKNGFMGYAVLDVENVQKEL-----LIWKDRAMIAEGQSKAFQLELKHANMSICSLSE 848
++ + + +++ +Q+E+ KDRA + + +S+ + KH M I L++
Sbjct: 3126 IINEKYRLEGQKTEIDRLQREVNQMMEYASKDRANLEKEKSE--MIAQKH-QMDI-ELNK 3181
Query: 847 KIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQS 668
+ IEER ++ L+T + +M L + +E+ K+ +++ + ++ LQ
Sbjct: 3182 ERGLIEERTQM----LNTYEKEMDQKRTALEVEMKELKYHKQAIQEEKNKLQQMKIELQR 3237
Query: 667 HFNQIQEML-LNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSD 491
+ I+++ +N LE ++ D+ ++ +A T D + E A +D
Sbjct: 3238 EADDIKKLKEKTRNERQSLEKMAE-NLEKEKDD-LAHLAEDTKRKDDEMKVLHESA-LAD 3294
Query: 490 KDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPE 365
+E L+ E++ +M+ + K+ L K +M E
Sbjct: 3295 IQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQQMQAE 3336
Score = 70.9 bits (172), Expect = 2e-09
Identities = 105/631 (16%), Positives = 253/631 (40%), Gaps = 12/631 (1%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L+ V +IQ+EK + + + +L+ + +RQ +I + +LE E+
Sbjct: 9915 LNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLE-----EEKL 9969
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEES-ISVLKQELSSARLQIESLE---KELNQANEE 1895
L +++ + E +R+ K E+ E+ + V+K++ +AR + E + +E Q NE
Sbjct: 9970 LVQIEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNEN 10029
Query: 1894 VKVL-----SKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-TCLQEVIE 1733
K L Q EL++ + L + E+ + R L ++K + E++
Sbjct: 10030 AKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILR 10089
Query: 1732 QKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFK 1553
Q++ E+++E M+ KL + +++ + ++ +D
Sbjct: 10090 QRDDLEKEKEDMMKK------------WNKLDVLQNEMQNENKAMEEIKYELDGKRNEIN 10137
Query: 1552 EESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNT 1373
+E ++ + + E + L +R + + Q+ E K L+ +KS+LE T
Sbjct: 10138 KEQQRLEESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKT 10197
Query: 1372 -MDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQME 1196
+D++ + +M +K + ++ RQ +E+E
Sbjct: 10198 EIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQ------------RQQMEDE-------- 10237
Query: 1195 EYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKI 1016
++EL+ + N E K + L ++ + + D L +L E +
Sbjct: 10238 -----RSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQRNDFKLKKEELALERQN--- 10289
Query: 1015 ELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQ 836
+V++ + +++N +++ + + +K+ ++ +Q+
Sbjct: 10290 -IVDEKYLLAQCETELQNKSEQI--------------RNMEEAVKNERETLKETEAHLQR 10334
Query: 835 IEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQ 656
++ K ++ + S + D++ ++ + + ++E+ + K+ L+ + + T Q ++
Sbjct: 10335 DKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDE 10394
Query: 655 IQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDE-E 479
+ Q ++ + M+E K E++N +I K E E
Sbjct: 10395 FDAQVRKQKEE-------DLTNQKKMEE----------ERKCLEEVNGKIIEMKTKAELE 10437
Query: 478 VIKLQSQVENLQSLVQMLKQQNTKLELLAKK 386
++ ++E LQ+L + + ++ K E + K
Sbjct: 10438 HHEINQKIEELQTLQEQIMKEKEKAEAMTIK 10468
Score = 70.5 bits (171), Expect = 3e-09
Identities = 135/717 (18%), Positives = 295/717 (41%), Gaps = 94/717 (13%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKETVKNLQSD-------LDIEQKLSTDRQSEIYSLSAELERIT 2081
D R DI+ K I + L V+ + D LDIE++ D Q + A+L+
Sbjct: 11654 DLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNEN 11713
Query: 2080 QSEQMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQAN 1901
+ + + +K+ ++TL E E+ L+ E EE SV+++ + +E + ++N+ N
Sbjct: 11714 ERIKEMDEEIKKEKETLKEMEAH---LRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQN 11770
Query: 1900 EEV----KVLSKFRYQV----LELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQ 1745
+++ +L + R ++ +L++ + A +SK E+ +++ +++ + +
Sbjct: 11771 QDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETK 11830
Query: 1744 -EVIE----------QKEVEERQRECMLAASERSND-------------INVNALEKKLS 1637
++IE +KE E+ + E M A E + ++ +KKL+
Sbjct: 11831 IKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLN 11890
Query: 1636 AYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSN--------ACDLLQEIENFLREIR 1481
+ I + + D+ ++ + +EE +++ N CD IEN +EI
Sbjct: 11891 DDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCD----IEN-SKEIV 11945
Query: 1480 VETKVTIQEARHNVE--------EFSSVVKHLEYL---KSQLETSN----------TMDH 1364
+ V ++E +H ++ E + + L KS+L+ N +
Sbjct: 11946 QKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKER 12005
Query: 1363 DTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEE--- 1193
+TL ++K +S T + + E +Q+L ++ +Q E
Sbjct: 12006 ETLKEMEAYLEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEIN 12065
Query: 1192 --YKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLK 1019
+K LQ ++ + + ++ + + L M + + K ++L + +AE +K
Sbjct: 12066 HKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANIL--EMKTKAEPEEIK 12123
Query: 1018 IELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQ 839
E EK + VE +KE+ K + + Q +L I E ++
Sbjct: 12124 KE-KEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLE 12182
Query: 838 QIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFN 659
+++ Q+ + +++ Q L + +I ++KE+++ + +E +Q
Sbjct: 12183 KMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKE 12242
Query: 658 QI----------QEMLLNQNVNYPLEATVNIGFDQSMD---EAVSEIAVQTFPNKDTEDI 518
++ Q++L+ + E D+ + E + E+ V K+ E+I
Sbjct: 12243 ELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNL--QKEKEEI 12300
Query: 517 NTEIAHTSDKDEEVIKLQS----QVENLQSLVQMLKQQ----NTKLELLAKKTSEMD 371
+ I T + E++ K+ + Q ++L + +LKQ+ N KL L ++ E +
Sbjct: 12301 ESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFE 12357
Score = 67.4 bits (163), Expect = 3e-08
Identities = 132/650 (20%), Positives = 266/650 (40%), Gaps = 34/650 (5%)
Frame = -2
Query: 2224 DIQKEK-NISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
+I EK NI + ++ Q+ + +K S D + ++ + E E + + K ++
Sbjct: 6815 EIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVE 6874
Query: 2047 EAEQTLLEAESERESLKAE---LEESISVLKQELSSARLQIESLEK-ELNQANEEVKVLS 1880
+ +Q L+ E + ESLK + E +KQ + ++Q + +EK +L +E +V
Sbjct: 6875 DLQQKLMSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRV-- 6932
Query: 1879 KFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-TCLQEVIEQKEVEERQRE 1703
++ +A + K E+ + + ++ K++ I E+ ++KE E R
Sbjct: 6933 -------------EEKTAQIQKEREEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRS 6979
Query: 1702 CMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNAC 1523
+ A ++ N N +E L+ + K LE +S + S K E
Sbjct: 6980 DLEKAKSQTFKQNKN-IEIALAEIQQKRNALEK------MSKEISRDRMKLE-------- 7024
Query: 1522 DLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTH 1343
+ K IQ AR +E ++ + K L S D L +
Sbjct: 7025 ---------------DEKKEIQLAREELERMHGDMQRQQEAKDHL-LSGITDESLLKKSE 7068
Query: 1342 -----QGSMEDKA----SSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEEC-------- 1214
Q S DKA ++ S D P +++ E+E+
Sbjct: 7069 AEIVLQPSQVDKAKPARKTEISDSDKQPVFVQQMPEMDLKDALKKDFESEKLDLPKVKDV 7128
Query: 1213 --KSKQME-EYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQL 1043
+ +QM+ E K+++ E++ L M AE+ K E D ++ K+ + N Q
Sbjct: 7129 LPQDQQMKLEQKLIEDEMDK-LKQMRAELQK-----------EADQIEKKKQDMQNERQK 7176
Query: 1042 RAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLE---LKHAN 872
+M++ E N E + +E+ I K + + Q+ AFQ+E +
Sbjct: 7177 LDDMAARLQEERRTN----------ERLNEEINIQK---VNQQKQATAFQMEKTDFERIK 7223
Query: 871 MSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNME 692
I ++++ +E+ K +T++ + ++ + A ++ E I++ + L
Sbjct: 7224 TEIDQANKELADQQEKNKKTITEMQKERETLEEMRANISKQVETITNENKSL-------- 7275
Query: 691 ASDTNLQSHFNQIQEMLLNQNVNY-PLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDI- 518
++ +S ++QE +L Q L+ T+ + Q +D+ S+I + K+ +D+
Sbjct: 7276 ---SSRESELAKLQEDILQQQQEMDELKNTIMMEMCQ-LDQRQSDIDLL---QKEVDDLM 7328
Query: 517 ---NTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSE 377
TE+A+ + E +++ +Q N++S + LK + E L K +E
Sbjct: 7329 DFTKTEMANV---ERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNE 7375
Score = 67.0 bits (162), Expect = 3e-08
Identities = 116/631 (18%), Positives = 263/631 (41%), Gaps = 25/631 (3%)
Frame = -2
Query: 2188 KETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTLLEAESER 2009
+E + +++++DIE+ + + ELE+I Q +AE E
Sbjct: 13133 REELAKMKTEIDIERDEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQHDEIHGGI 13192
Query: 2008 ESLKAELEESISVLKQELSSARLQIESLEKELNQANEEV-KVLSKFRYQVLELE--EYSQ 1838
+SLK E EE I +K +L + + E++ + + +E+ K ++ +E E + +
Sbjct: 13193 DSLKEEREE-IEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDK 13251
Query: 1837 QLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVN 1658
L ++ K+ A L+ +KN + + E + +E E + C + E++ ++N
Sbjct: 13252 NLQDEMMKI----EAILKVTKKQKNYLEQMNENL-TREKTELETNCQMLEREKT-ELNKK 13305
Query: 1657 ALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRV 1478
E + + K+ E + + +D A EE K+ +E+ N EI+
Sbjct: 13306 VKETE-EFHMSKMEEREAERKTIERVMDEMA----EEHEKIKKE---REELVNMEEEIKK 13357
Query: 1477 ETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTG 1298
+ +V ++ E + L++ +S+L D ++S + ++ + S Q
Sbjct: 13358 QRRV----LEESMNEMTKKKSELQHERSELYKQKQQLEDMIASESKRDVDTERSRQDKED 13413
Query: 1297 DNDPKAXXXXXXXXXXXECRQNLENEECK---SKQMEEYKMLQAELNNWLSCMNAEMGKF 1127
+ K ++ + E K +++ E + +Q++LN+ M+ E K
Sbjct: 13414 EQILKREREEIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKL 13473
Query: 1126 LCL-------CNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDV 968
L + N++ + D+ K +E++ Q + E I + E +A ++
Sbjct: 13474 LYMKTEIQVKTNALEKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEI 13533
Query: 967 ENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKD 788
+ +++ K R + Q ELK + SE+++ + ++++ + TK+
Sbjct: 13534 QRQFEDIESVKVRLVTESNQIDKMNSELK-------TRSEELENLIKKQQ---KEFETKE 13583
Query: 787 TDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEM--LLNQNVNYPL 614
+MQ L E+ LK+ I+ + + +LQ N+ +E+ +L + +
Sbjct: 13584 NEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREKSELY 13643
Query: 613 EATVNIGFDQSMDEAVSEIA------VQTFPNKDTEDINTEIAHTSDKDEEVIKL----Q 464
+ + + E + + ++ N+ ++ + ++ S + E+ KL Q
Sbjct: 13644 QEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTEIQ 13703
Query: 463 SQVENLQSLVQMLKQQNTKLELLAKKTSEMD 371
S+ E+++ + LKQ + E K +++D
Sbjct: 13704 SEKESIEEEKKTLKQLKDENE---SKRTQLD 13731
Score = 66.2 bits (160), Expect = 6e-08
Identities = 137/696 (19%), Positives = 288/696 (41%), Gaps = 63/696 (9%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKE-------TVKNLQSDLDIEQKLSTDRQSEIYSLSAELERIT 2081
D + I KEK S ++E T + + +++ E++ RQ E+ E+ERI
Sbjct: 546 DVEKAKILKEKEESIRIREEARQERETTELVNAEIKAEKERLNQRQEEMLRERQEIERIK 605
Query: 2080 QSEQMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQAN 1901
+ + ++ ++ + + E +KAE++ I +++++ + E +E+ +
Sbjct: 606 HETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKEQMEEAKVELE 665
Query: 1900 EEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITC---------- 1751
EE + L + R V E ++ L ++ +V E+ + R+ ++ E+
Sbjct: 666 EEREDLERKRDLVSREIEQAEFLRNEILRVKEEMESRWRETETEEVELRAKTQHELERLE 725
Query: 1750 -LQEVIE--QKEVEERQRECML-------AASERSNDINVNALEKKLSAYEGKIRRLEND 1601
L+E E QK +EE + E ML E D +V ++ ++ + K +L
Sbjct: 726 KLREETERSQKNIEESKIELMLWKESLDKLKGEMEEDKHVVIMQ--MNEAKAKEEQLTMV 783
Query: 1600 VSQLTL---SVDFSAGVFKEESTKVSNACDLLQ----EIENFLREIRVETKVTIQEARHN 1442
+ QL + + S KEE +++ + LQ E+E++ R + E K A+
Sbjct: 784 IEQLEIERGEITISREKVKEELDEINRMRNELQRQHAEMEDWFRVVNKE-KEEANLAKLA 842
Query: 1441 VEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXX 1262
V E + LK Q+E S ++ ++ ++E + Q KA
Sbjct: 843 VHEAEML------LKKQMEESEKRRYEMITE----ALEQRDEIQK-------KAEELEQI 885
Query: 1261 XXXXXECRQNLE-----NEECKSKQME---EYKMLQAELNNWLSCMNAEMGKFLCLCNS- 1109
RQ LE +E K +E + ++ ++ + L A+ K L +S
Sbjct: 886 NKEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLFEMDSE 945
Query: 1108 ---MVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLI- 941
+ + + K+DL Q R EM VE++ + ++E ++ +L+I
Sbjct: 946 RKELEQMRFQVENEKKDL----EQRRYEMMRYD---VEQSAQVQRQKEELEKIKSQLVID 998
Query: 940 ----WKDRAMIAEGQSKAFQL--ELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDM 779
+ R + + + KA L E++ + E+ +Q EE ++L + + D+
Sbjct: 999 TESMNRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRLLRKDMENEREDL 1058
Query: 778 QHLAAQLTL--------AQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVN 623
+ + + TL +EEI+ + ++ D E D + N +E ++ +
Sbjct: 1059 EKIRVE-TLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRK--- 1114
Query: 622 YPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIK--LQSQVEN 449
+EA + M E + ++ V+ K+ D+ E A + E++K L Q E+
Sbjct: 1115 --MEA-----MKREMGE-IEDMKVELTKQKENIDMKMEHARLEMTNLEMMKADLLRQKED 1166
Query: 448 LQSLVQMLKQQNTKLELLAKKTSEMDPEKYFHFEEL 341
+++ + K + ++E++ + + + EE+
Sbjct: 1167 IENQMLAAKSERQQMEVMRTEILKQKEDLEERLEEV 1202
Score = 65.5 bits (158), Expect = 1e-07
Identities = 142/774 (18%), Positives = 319/774 (41%), Gaps = 66/774 (8%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
+++ ++ + ED K ++N++ +L E + ++ +E + + + L++
Sbjct: 1554 NLEAQRKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEK 1613
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQ 1865
+ + ++ER +LE + + L+ + + + LEK +++ N + K +
Sbjct: 1614 KRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEK-ISELNSQQKDEIENEKS 1672
Query: 1864 VLELEEYS-QQLSADLSKVHEDYSAALRQLFDKKNEITCLQ-EVIEQ-KEVEERQRECML 1694
+++ EY QQ+ DL++ ++ +F +K+E+ Q E+ EQ K+V + +
Sbjct: 1673 KIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQDEIAEQLKQVGDMMQ---F 1729
Query: 1693 AASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLL 1514
+E+ N L+++ +A + ++E D++ L S + K+E V N LL
Sbjct: 1730 TQNEKDN------LDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKE---VLNEKRLL 1780
Query: 1513 QEIE-NFLREIR--VETKVTIQEARHNVE-EFSSVVKHLEYLKSQLET----SNTMDHDT 1358
++ + +R+++ + K+ ++ + ++ + S+ + + L+S L+T + + DT
Sbjct: 1781 EDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDT 1840
Query: 1357 LSSTHQGSMEDKA---------------SSQSSTGDNDPKAXXXXXXXXXXXECRQNLEN 1223
L+ + +ED A ++ D D + + +L+
Sbjct: 1841 LAEKQK--LEDAAVELQKERDEIMNIAEETKRKREDVDKIRVGIEKQEITFKDLKADLQK 1898
Query: 1222 E--------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKED 1067
E + K ++ K ++ ++ M+ + + ++ ++ ++ K +++
Sbjct: 1899 EAAIVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVDKERQE 1958
Query: 1066 LLLNHGQLRAEMSSLKIE------LVEKNGFMGYAV--------LDVENVQKELLIWKDR 929
+ +L E S L+ + EKN + + L EN+ KE I
Sbjct: 1959 VESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTI---- 2014
Query: 928 AMIAEGQSKAFQLELKHANMSICSLSEKIQQIEE------REKVLLTQLSTKDTDMQHLA 767
F+LE +H + K +QI+E EKV + Q+ D D Q
Sbjct: 2015 ----------FELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQA-DKDQQRKK 2063
Query: 766 AQL--------TLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLE 611
A+ T A EE E L++ +N+E + H N+ +E+ ++ + +E
Sbjct: 2064 AEYVKTARGRETTALEEQRQEMESLREEYENVEKQ----KKHVNEQKELFESRMKSLEME 2119
Query: 610 ATVNIGFDQSMDEAVSEIAVQ-TFPNKDTEDINTEIAHTSDKDEEVIK-LQSQVENLQSL 437
+ + +D+ ++ Q K+ + + TE+ ++ E K L+ Q + +
Sbjct: 2120 NEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTE 2179
Query: 436 VQMLKQQNTKLELLAKKTSEMDPEKYFHFEELCQSLVXXXXXXXXXXXXXXXKNQVLVKQ 257
ML+ Q +E KT E+D + +L S V + + VK+
Sbjct: 2180 TYMLETQKPVVE--KSKTDELDEVRKKINADL--SEVEKQKSALVQMNLKISQEESYVKK 2235
Query: 256 VKEMQVTLQSESPMEGETDSISENAIGSQPA--GKLSTELHNVHGNTERVPLQL 101
K+ ++E M+ + +N + + A K EL NV E+ +++
Sbjct: 2236 EKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEI 2289
Score = 65.5 bits (158), Expect = 1e-07
Identities = 135/673 (20%), Positives = 272/673 (40%), Gaps = 57/673 (8%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQ--------KLSTDR---QSEIYSLSAELERITQ 2078
D+QKEKN +E+LK ++ +S+L E+ ++ T R +SE+ +L +
Sbjct: 13620 DLQKEKNKTEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELED 13679
Query: 2077 SEQMSLKRLK----EAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELN 1910
++ L RL E ++ E +SE+ES++ E ++++ LK E S R Q+++ +++N
Sbjct: 13680 EKKSMLSRLSMEKHEIDKLKTEIQSEKESIEEE-KKTLKQLKDENESKRTQLDNTIEKMN 13738
Query: 1909 ----------QANEEVKVLSKFRYQVLELE-----EYSQQLSADLSKVHED--------- 1802
+ EE+K + + + L+ E + + Q+S D + +D
Sbjct: 13739 MDKLSIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRS 13798
Query: 1801 -YSAALRQLFDKKNEITCLQ---EVIEQKEVEERQRECMLAASERSNDINVNALEKKLSA 1634
+ RQ ++++ LQ E++E+ + E L + ND+ + L K+ A
Sbjct: 13799 MRADIERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEKQRKRNDLTLQELRKEKMA 13858
Query: 1633 YEGKIRRLEND---VSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVT 1463
E I + + V+ L V K + T++ + ++ L + T
Sbjct: 13859 LEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQ 13918
Query: 1462 IQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPK 1283
QE + E + LE +K+ L+ D + + S + D
Sbjct: 13919 QQEVDVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDEL 13978
Query: 1282 AXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMV 1103
+ E + +K++ + K LN + E+ S+
Sbjct: 13979 EKFTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLE 14038
Query: 1102 YLEGDILKYKED---LLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWK- 935
L D+L +D L+ Q+ E + K E VE + ++E ++ + K
Sbjct: 14039 QLRADLLAGADDIKTLVQTEKQMAIEDTEKKTE-VELQMNLQKQKNELEELRNTIEAEKH 14097
Query: 934 ---DRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAA 764
+R ++ + Q K + I ++ + + + E+EK L +LS L
Sbjct: 14098 QVENRKIMLDKQQKEVE--------DIMTVIKSERDVLEKEKSELNKLS------HVLNE 14143
Query: 763 QLTLAQEEISSTKEMLKDFIDN----MEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNI 596
++ QEE+ E +D I+N +E+ +++ +++ L + V E T+ +
Sbjct: 14144 KVQREQEELERLLEKERDDIENCKKIIESEKQSIERERAELKR--LKEEVEVQHERTL-L 14200
Query: 595 GFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQ 416
D++M + K+ E + E A T+ EE+ L+ +++ S + ML +
Sbjct: 14201 QQDKNMIQ------------KEKEHLEGEKARTT---EEIHNLKEEIKRKSSELDMLNK- 14244
Query: 415 NTKLELLAKKTSE 377
E+ AK+ E
Sbjct: 14245 ----EIEAKRQEE 14253
Score = 64.7 bits (156), Expect = 2e-07
Identities = 117/652 (17%), Positives = 266/652 (40%), Gaps = 26/652 (3%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L+ + D+QK K +E + L+ + QSE+ SL+ E++ + Q +
Sbjct: 14562 LNKAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIK--- 14618
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVL---KQELSSARLQIESLEKELNQANEEV 1892
E +Q ++ + + S+ + E + + ++ + + + E+E++ +
Sbjct: 14619 ----TEMQQIEIKMQIQTRSVATQWETDVQIQQEGQEPIETTGHITKKSEEEISAKKTKQ 14674
Query: 1891 KVLSKFRYQVL-ELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVE- 1718
+++K + E++E D++++ QL K++I E E+ E
Sbjct: 14675 PIVTKLEDTLTSEVQEMRDMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEET 14734
Query: 1717 ----ERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
R E +L +D++ N L++K E + +++QL ++ + K+
Sbjct: 14735 LKEKSRNEETLLQLLHDKDDLS-NTLDEKSKEIENITVTFKRNIAQLETTI----AMMKK 14789
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTM 1370
+ + N L++ E REI+ T T E E + V + L+ E
Sbjct: 14790 DKENIENELLQLKQTEQ-EREIQRGTDDTSNER----ENYDEKVTYKTELEDSKEKKKPD 14844
Query: 1369 DHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-ECKSKQMEE 1193
+L T S + ++ T + K + ++ L +E E K K + E
Sbjct: 14845 RDSSLKLTDADSAKTDGEREAQT--LETKVQDVLQLTDYTTQDQEELHDEMENKMKIILE 14902
Query: 1192 YKMLQAELNNWL-SCMNAEMGKFLCL------CNSMVYLEGDILKYKEDLLLNH-GQLRA 1037
+ +L C +AE K + + NS+ ++ ++L ++ ++H Q++
Sbjct: 14903 LNEAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQE--IDHLAQIKT 14960
Query: 1036 EMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICS 857
EM ++I++ + +V + W+ I +GQ E I
Sbjct: 14961 EMQQIEIKM----------QIQTRSVATQ---WETDVQIQQGQ------EATETTGHITK 15001
Query: 856 LSEKIQQIEEREKVLLTQL-STKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDT 680
SE+ ++ ++ +T+L T +++Q + L E+++ K ++K D +E + +
Sbjct: 15002 KSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVARMKTIMKMEKDQLEQAKS 15061
Query: 679 NLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAH 500
++Q+ + F+++M+EA+ E + ++++
Sbjct: 15062 DIQTQMEE---------------------FERNMEEAMEEKSRNEEKLLQLTHDKEDLSN 15100
Query: 499 TSDKDEEVIKLQSQ-----VENLQSLVQMLK--QQNTKLELLAKKTSEMDPE 365
T DK + I+ ++ + L++ + ++K ++N + ELL K +E + E
Sbjct: 15101 TLDKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQERE 15152
Score = 63.9 bits (154), Expect = 3e-07
Identities = 125/676 (18%), Positives = 275/676 (40%), Gaps = 49/676 (7%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDL-------KETVKNLQSDLDIEQKLSTDRQSEIYSL-SAELER 2087
++ + D+Q E+ +D+ + T + L +++I QK++ +Q+ + + + ER
Sbjct: 7163 IEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINI-QKVNQQKQATAFQMEKTDFER 7221
Query: 2086 ITQSEQMSLKRLKEAEQ----TLLEAESERESLKAELEESISVLKQELSSARLQIESLEK 1919
I + K L + ++ T+ E + ERE+L+ E+ +IS + +++ + S E
Sbjct: 7222 IKTEIDQANKELADQQEKNKKTITEMQKERETLE-EMRANISKQVETITNENKSLSSRES 7280
Query: 1918 ELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEV 1739
EL + E++ Q E++E + ++ QL ++++I LQ+
Sbjct: 7281 ELAKLQEDI------LQQQQEMDELKNTIMMEMC-----------QLDQRQSDIDLLQKE 7323
Query: 1738 I---------EQKEVEERQRECMLAASERSNDINVNALEK------KLSAYEGKIRRLEN 1604
+ E VE + E + +D+ +EK +L E K +E
Sbjct: 7324 VDDLMDFTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNEEK-DLIEK 7382
Query: 1603 DVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS 1424
+ LT ++D + + ++ N + I+N +E+ + K+++Q +EFS
Sbjct: 7383 ERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKELE-KMKISLQRKAIGFKEFSE 7441
Query: 1423 VVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXE 1244
K + ++ T D +G ++ Q+ + K E
Sbjct: 7442 KTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQT-----EKKRRKTYYTEDLFQE 7496
Query: 1243 CRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL 1064
+ +L+ K EE + E+ + +N E + S + +I K KE +
Sbjct: 7497 EKTDLQ------KTKEEINYDREEIYRQRTELNKEKETLKQMHTSNLKEIENIEKEKEKI 7550
Query: 1063 LLNHG---QLRAEMSSLKIELVEKNGFM----GYAVLDVENVQKELLIWKDRAMIAEGQS 905
Q+RAE+ + + ++ + M D+EN+Q E KD +
Sbjct: 7551 QRTWNELDQIRAELQNKQRDMDDTTNIMMKEKAELARDLENLQNE----KDELQKSRENI 7606
Query: 904 KAFQLELKHANMSIC-SLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISST 728
+ EL+ + +L+++ QQ E ++ K+ + + A++ + + +
Sbjct: 7607 QKLMKELQEERLKTSEALNKERQQFTE-------EIKLKNDSLDEIQAEIDRQKRALVTD 7659
Query: 727 KEML-KDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNI-----GFDQSMDEAV 566
KE++ K +D + D QS + I L + + +V I ++ DE +
Sbjct: 7660 KEIITKQMMDLQKTQDVRRQSDESDIARANLQRERESLDQLSVEILKQKQDLERERDELL 7719
Query: 565 SE---IAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQ-----VENLQSLVQMLKQQNT 410
+ + Q N++ + + TE+ + E++ K Q EN +L + L++ N
Sbjct: 7720 EQWRLVETQKMDNENVKQLKTELLDEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNL 7779
Query: 409 KLELLAKKTSEMDPEK 362
+ + + + ++++ K
Sbjct: 7780 QKQGIQDERAQLERMK 7795
Score = 63.9 bits (154), Expect = 3e-07
Identities = 130/706 (18%), Positives = 276/706 (39%), Gaps = 79/706 (11%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLD--------IEQKLSTDR------------- 2126
++ +R DI +EKN ++ +SDL+ +Q + +R
Sbjct: 12849 IEKIRQDIDREKN-------DLEKYRSDLEKQYEEMEICKQNIENERAELEIDLENIIIE 12901
Query: 2125 ----QSEIYSLSAELE---------------RITQSEQMSLKRLKEAEQTLLEAESERES 2003
Q + S+ +L+ R + + + K +E EQ E E++
Sbjct: 12902 TKSKQERLESIEVQLQEKNVQMGTILDELNKRQEELDAIKAKTQREKEQMGHTEELEKDE 12961
Query: 2002 LKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSAD 1823
L A L++ ++K+ + + Q E L+KE +Q L K + LE+E + L+++
Sbjct: 12962 LIAILQKREEIVKRHMEEIQNQREELQKEKDQFGNMQAELQKGQ---LEMEMHQLMLNSE 13018
Query: 1822 ----------LSKVHEDYSAALRQLFDKKNEITCLQEVI-EQKEVEERQRECMLAASERS 1676
L K E++ + L ++ E + L++++ E+K VEE M A +
Sbjct: 13019 RDELNGMRVNLEKQKEEFELMQQNLESRRPE-SLLEDILKEKKRVEE-----MAAQLSKE 13072
Query: 1675 NDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDL----LQE 1508
+ N + + + E KI+++E ++ + + + ++E + N + LQ
Sbjct: 13073 QEEFRNIMSETIKRME-KIKQIEGEIKTKQIEMACLEELKQKELDEQKNMRECENQELQM 13131
Query: 1507 IENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSN------TMDHDTLSST 1346
L +++ E + E + +++ LE +K L+ + HD +
Sbjct: 13132 RREELAKMKTEIDIERDEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQHDEIHGG 13191
Query: 1345 HQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELN 1166
E++ + D K + LE +E + +QM ++ E N
Sbjct: 13192 IDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQM----AVETEDN 13247
Query: 1165 NWLSCMNAEMGKFLCLC-------NSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELV 1007
+ + EM K + N + + ++ + K +L N L E + L ++
Sbjct: 13248 DSDKNLQDEMMKIEAILKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNKKVK 13307
Query: 1006 EKNGFMGYAVLDVENVQKELLIWKDRAM--IAEGQSKAFQLELKHANMSICSLSEKIQQI 833
E F + + E +K + +R M +AE K +K + ++ E+I++
Sbjct: 13308 ETEEFHMSKMEEREAERKTI----ERVMDEMAEEHEK-----IKKEREELVNMEEEIKKQ 13358
Query: 832 EEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQ-SHFNQ 656
+ + +++ K +++QH + E+ K+ L+D I + D + + S ++
Sbjct: 13359 RRVLEESMNEMTKKKSELQH-------ERSELYKQKQQLEDMIASESKRDVDTERSRQDK 13411
Query: 655 IQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEV 476
E +L + E ++++ Q K+ ED+ T + + E +
Sbjct: 13412 EDEQILKRE-----------------REEIADMKDQLL--KEKEDVETTKERINREKEHI 13452
Query: 475 IKLQSQVENL--------QSLVQMLKQQNTKLELLAKKTSEMDPEK 362
K+QSQ+ + Q L+ M + K L K ++ E+
Sbjct: 13453 EKMQSQLNDQKEEMDLENQKLLYMKTEIQVKTNALEKMMQDLQKER 13498
Score = 63.5 bits (153), Expect = 4e-07
Identities = 110/654 (16%), Positives = 277/654 (42%), Gaps = 44/654 (6%)
Frame = -2
Query: 2230 RLDIQKEKNISEDL-------KETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSE 2072
+ DI+ K I + L K ++ + +LDIE++ D Q + +EL+ +
Sbjct: 10821 KCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERI 10880
Query: 2071 QMSLKRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKEL-NQA 1904
+ + +K+ +TL E E+ E K E++ E LK++L + K+L NQ
Sbjct: 10881 RNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRLKEDLEKMSTDVNKQNKDLMNQR 10940
Query: 1903 N----EEVKVLSKFRYQVLELEEYSQQLS----ADLSKVHEDYSAALRQLFDKKNEITCL 1748
+ E ++ K++ ++E+ Q+S DL K + + L + K + +
Sbjct: 10941 DLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPK-EKGMKEDRKSLEETKANVIEM 10999
Query: 1747 QEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFS 1568
+ E +E+++ + + E +I V ++ Y+ +++++ ++ +D
Sbjct: 11000 KTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELYQ-----IKSELERVRSEID-- 11052
Query: 1567 AGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQL 1388
E K+++ ++++ + L +++ E Q+ E + ++ K +
Sbjct: 11053 -----HEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDI 11107
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKS 1208
E S + + E + Q + D + + + L+NE +
Sbjct: 11108 EKSKEIVEKLMVEVE----EQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERI 11163
Query: 1207 KQM-EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEM 1031
K++ EE K + L + E + + + D+ K D+ L+ +
Sbjct: 11164 KKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQR 11223
Query: 1030 SSLKIELVEKNGFMGYAVLDVE------NVQKELL----IWKDRAMIAEGQSKAFQLELK 881
L+ E E N M ++ + Q+E L + ++R + E +++ +++ K
Sbjct: 11224 DLLEQEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTK 11283
Query: 880 HANMSICSLSEKIQQIEEREKVLL----TQLSTKDTDMQHLAAQLTLAQEEISSTKEMLK 713
I + EK ++ EE +V++ +L+ ++++ + +++ Q++++ K++++
Sbjct: 11284 AELQEI--MQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIE 11341
Query: 712 DFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFD-QSMDEAVSEIAVQTFPN 536
+++E + + + Q++E ++ ++ T D ++ E V ++ V+
Sbjct: 11342 QEKEDLEKMKSEIMTQRQQMEEE--RSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQ 11399
Query: 535 K-----DTEDINTEIAHTSDKDEEVI----KLQSQVENLQSLVQMLKQQNTKLE 401
+ E+++ E +D+ V+ KLQ++ E ++ + + +K++ L+
Sbjct: 11400 RKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLK 11453
>ref|XP_685984.6| PREDICTED: titin isoform X7 [Danio rerio]
Length = 15997
Score = 105 bits (261), Expect = 1e-19
Identities = 135/637 (21%), Positives = 287/637 (45%), Gaps = 30/637 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD + ++ K++ D+ ET+KN + LD +++ +++ EI + ++ S
Sbjct: 3781 LDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDED 3840
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEE---SISVLKQELSSARLQIESLEKELNQANEEV 1892
LK +K +Q E +++ E +K ELE I +K+E+ + R +E + +EL + E
Sbjct: 3841 LKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESF 3900
Query: 1891 KVL---SKFRYQVL-ELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKE 1724
L +K ++L E++ ++ L A+L K ++ + + ++ +E + +E
Sbjct: 3901 THLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLRE 3960
Query: 1723 VEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEES 1544
E Q + + +R + + +E + +A I ++ D+ +S+D A K +
Sbjct: 3961 DELGQLQAEIHKQQREIEKEKSNIESERAA----IIKIVEDLQHKIISLDRDAESLKLDR 4016
Query: 1543 TKVSNACDLLQ----EIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQLETS 1379
N ++L+ E+E EI + K+ Q R VEE ++ + K + + + +E +
Sbjct: 4017 EAFENEREVLKQMKTELERETDEIE-KIKLETQHDRQRVEEMTAQITKERDKINNLIEET 4075
Query: 1378 NTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE------- 1220
N D L+ ++ E S QS + + + +++LE +
Sbjct: 4076 NRKDM-VLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQKENTLAE 4134
Query: 1219 -----ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLN 1055
E K E + E+ + M + + L + L+ ++ K KE ++ +
Sbjct: 4135 IQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKD 4194
Query: 1054 HGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHA 875
R+E+ + EL ++ M + ++N +K L+ KD+ + E Q + + E +
Sbjct: 4195 ----RSELDLRQSELDKQQTNMNDIIETMKNERK--LLDKDKEEMEE-QKQEMEKERDNM 4247
Query: 874 NMSICSLSEKIQQIEEREKVL---LTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFI 704
+ SI SL E ++ ++ +++V+ +L ++Q A ++ +EE + ++ L+
Sbjct: 4248 DQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQNERQSLEKMT 4307
Query: 703 DNM--EASD-TNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNK 533
+ E D +L + + +EML V A + D ++ + E + +K
Sbjct: 4308 KALIKEREDLVHLAEYTKREKEMLDEMQV-----ANKSSMADLQREKRILEEMRENI-SK 4361
Query: 532 DTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
TEDI E + +++E+ KLQ++V+ QS + M K
Sbjct: 4362 QTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEK 4398
Score = 102 bits (253), Expect = 9e-19
Identities = 127/657 (19%), Positives = 292/657 (44%), Gaps = 30/657 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD + ++ K++ D+ ET+KN + LD +++ +++ E+ +++ +S
Sbjct: 6611 LDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDED 6670
Query: 2062 LKRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQANEEV 1892
LK +K +Q + E +++ E +K ELE + I +K+E + R +E + +EL + ++V
Sbjct: 6671 LKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDV 6730
Query: 1891 KVLS----KFRYQVLELEEYSQQLSADLSK-------VHEDYSAALRQLFDKKNEITCLQ 1745
L+ + + + E++ ++ ADL K + E+ S + +K++I +
Sbjct: 6731 AHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLRE 6790
Query: 1744 EVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSA 1565
+ +EQ + E +++ + + + A+ K + + KI L+ D L L +
Sbjct: 6791 DELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDRE--- 6847
Query: 1564 GVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQL 1388
F+ E ++ L+ + + +I++ET Q R VEE ++ ++ + + QL
Sbjct: 6848 -AFENEKEELKQMKTELEREADEIEKIKLET----QHERQRVEEMTADFMETMNNERKQL 6902
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKS 1208
+ + M E K + D D +Q LE E+ K
Sbjct: 6903 DKNKVMIE-----------EQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKL 6951
Query: 1207 KQM--------EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL---- 1064
+QM +E ++ E N + L YL +I + + L
Sbjct: 6952 EQMKIGLEREADEISKIKEETQNERQNLEKMAN---ALKEEREYLAEEIKRKNQVLDKIK 7008
Query: 1063 LLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKD--RAMIAEGQSKAFQL 890
+ N L A++ K L E + + D+EN +++ + +D + + E Q + ++
Sbjct: 7009 VANESTL-ADLQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEI 7067
Query: 889 ELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKD 710
+++ N+ SE+ I E++ ++T+L K D++ ++ +E + + + +LK
Sbjct: 7068 DMEKTNIE----SERAAMIREKQN-MMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKK 7122
Query: 709 FIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKD 530
+++++ +++ ++++ EA N ++M + +++ +Q +
Sbjct: 7123 DVEDLQQKLMSIERD---------SESLKLDKEAFEN--EKEAMKQMKTDLQIQA---DE 7168
Query: 529 TEDINTEIAHTSDK-DEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEK 362
E I E H + +E+ ++Q + E + +LV+ +K+ K +++ + +E+ EK
Sbjct: 7169 IEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIKK---KRDIIDESYTEIRKEK 7222
Score = 100 bits (250), Expect = 2e-18
Identities = 128/638 (20%), Positives = 274/638 (42%), Gaps = 31/638 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD + ++ K++ D+ ET+KN + LD +++ + +++ E+ + ++ +S
Sbjct: 5324 LDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 5383
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEE---SISVLKQELSSARLQIESLEKELNQANEEV 1892
LK +K +Q L + +S+ E +K ELE I +K+E+ + R +E + + L + E++
Sbjct: 5384 LKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL 5443
Query: 1891 KVLSKFRYQVL-ELEEYSQQLSAD-------LSKVHEDYSAALRQLFDKKNEITCLQEVI 1736
+K QVL E++ ++ AD L ++ E+ S + +KK + ++ +
Sbjct: 5444 AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDEL 5503
Query: 1735 EQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTL---SVDFSA 1565
Q + E +++ + + + + A+ K + + KI L+ D L L + +
Sbjct: 5504 RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEK 5563
Query: 1564 GVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQL 1388
V K+ T++ D +++I K+ Q R VEE ++ + K + + + +
Sbjct: 5564 EVLKQMKTELEREADEIEKI-----------KLETQHDRQRVEEMAAQIQKDRDEINNLI 5612
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE---- 1220
E +N D L+ ++ E S QS + + + +++LE +
Sbjct: 5613 EETNRKDM-VLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENT 5671
Query: 1219 --------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL 1064
E K E E+ + MN + + L + L+ ++ K KE +
Sbjct: 5672 LAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEII 5731
Query: 1063 LLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLEL 884
+ + QL S L + N M ++N +K+L KD+ + E Q + + E
Sbjct: 5732 MKDRSQLDLRQSELDKQQTNMNDIME----TMKNERKQL--DKDKEEMEE-QKQEMEKER 5784
Query: 883 KHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFI 704
+ + S SL E +++ K+ + ++ + +L +EIS KE ++
Sbjct: 5785 DNMDQSRKSLDED----QKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKR 5840
Query: 703 DNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAV----QTFPN 536
+E L + + + + + + + SM + E ++ + +
Sbjct: 5841 QRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENIS 5900
Query: 535 KDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
K E I+ E + +++E+ KLQ++V+ QS + M K
Sbjct: 5901 KLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEK 5938
Score = 95.5 bits (236), Expect = 9e-17
Identities = 119/641 (18%), Positives = 277/641 (43%), Gaps = 34/641 (5%)
Frame = -2
Query: 2242 LDAVRLDIQKEKN----ISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQS 2075
++ ++L+ Q E+ ++ D ET+ N + L+ ++ +++ E+ ++++ +S
Sbjct: 4903 IEKIKLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKS 4962
Query: 2074 EQMSLKRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQA 1904
+LK +K +Q + E +++ E +K ELE + I +K+E + R ++E + +EL +
Sbjct: 4963 LDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEADEIRKIKEETQNERQRLEKMTEELKKE 5022
Query: 1903 NE-----------EVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI 1757
E E K+L K + L Q+ ++L ++ E+ S +K +I
Sbjct: 5023 KESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKI 5082
Query: 1756 TCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSV 1577
++ +EQ + E +++ + + +N+ A+ K + + K+ L+ D+ L L
Sbjct: 5083 RLREDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRDLESLKLDR 5142
Query: 1576 DFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYL 1400
+ F+ E + L+ + +I++ET Q R VEE ++ + K + +
Sbjct: 5143 E----AFENEREVLKQIKTDLKRKAEEIEKIKLET----QHDRQRVEEMTAQIQKERDKI 5194
Query: 1399 KSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE 1220
+ +E +N D L+ E + +S + + ++NLE +
Sbjct: 5195 NNLIEETNRKDM-VLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQ 5253
Query: 1219 ------------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKY 1076
E K E++ + ++ + M + + L + L+ ++ K
Sbjct: 5254 RKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQQELEKE 5313
Query: 1075 KEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAF 896
KE ++ + QL S L + N M ++N +K+L K+ E Q +
Sbjct: 5314 KEIIMKDRSQLDLRQSELDKQQTNVNDIME----TMKNERKQLDKDKEE---TEEQKQEM 5366
Query: 895 QLELKHANMSICSLSEKIQQIEEREKVL---LTQLSTKDTDMQHLAAQLTLAQEEISSTK 725
+ E + S SL E ++ ++ +++VL ++L +++ A ++ +EEI + +
Sbjct: 5367 EKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNER 5426
Query: 724 EMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQT 545
+ L+ + ++ +L + ++L V + +++E I
Sbjct: 5427 QNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENI---- 5482
Query: 544 FPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
+K TED+ + + +++E+ +LQ+++ Q ++ K
Sbjct: 5483 --SKQTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEK 5521
Score = 95.1 bits (235), Expect = 1e-16
Identities = 127/646 (19%), Positives = 274/646 (42%), Gaps = 26/646 (4%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
D+Q+EK+I E+++E + L+ +D E++ S R+ E+ L E++ K+ +
Sbjct: 5884 DLQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQ----------KQQSK 5933
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSK---- 1877
+ ESER ++ E + ++ LK++ +Q++ + E + + K+L++
Sbjct: 5934 IDMEKTNIESERAAMIREKQNMMTELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVEN 5993
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVE---ERQR 1706
+ ++++LE S++L D + E+ A++Q+ K ++ + IE+ ++E +RQR
Sbjct: 5994 LQQKLIDLERDSKRLKLD-REAFENEKEAMKQM---KTDLQIQADEIEKIKLETQHDRQR 6049
Query: 1705 ECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNA 1526
+AA + +N L ++ + + + D+ + S+ + ++E +
Sbjct: 6050 VEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKT 6109
Query: 1525 CDLLQEIENFLREIRVETKVTIQEARHNVEEFS-SVVKHLEYLKSQLETSNTMDHDTLSS 1349
L +++ L + + T IQ+ R +VE+ + ++ + + +K Q E N
Sbjct: 6110 RSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMN--------- 6160
Query: 1348 THQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-ECKSKQMEEYKMLQAE 1172
+D+ + N +Q LE E E K ++ + Q+E
Sbjct: 6161 ----QKQDELDQLKTEIQN----------------LQQELEKEKEIIMKDRSQFDLRQSE 6200
Query: 1171 L-------NNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIE 1013
L N+ + M E + M + ++ K K D + L ++ +K++
Sbjct: 6201 LDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKDLKMMKLQ 6260
Query: 1012 ---LVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSE-- 848
E+ + +++E E+ K+ + ELK S L+E
Sbjct: 6261 KQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFTHLAEDT 6320
Query: 847 -KIQQIEEREKV----LLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASD 683
K Q+I ++ KV L+ L + ++++ + ++ E++ + KE L+ D +
Sbjct: 6321 KKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLREDEL---- 6376
Query: 682 TNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIA 503
LQ+ + Q + + +N E I K+ ED+ +I
Sbjct: 6377 WQLQAEIYKQQREIEKEKINIESERAAII--------------------KNVEDLQHKII 6416
Query: 502 HTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPE 365
+ D+D E +KL E ++ ++LKQ T+LE A + ++ E
Sbjct: 6417 -SLDRDSESLKLDR--EAFENEREVLKQMKTELEREADEIEKIKLE 6459
Score = 92.0 bits (227), Expect = 1e-15
Identities = 137/648 (21%), Positives = 278/648 (42%), Gaps = 30/648 (4%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIE-QKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++ +K+I E+ + + DL E K S D + ++ + E E + ++ K ++
Sbjct: 3594 EMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLTEKELLESDRKLLKKDVE 3653
Query: 2047 EAEQTLLEAESERESLKAE---LEESISVLKQELSSARLQIESLEKELNQANEEVKVLSK 1877
+Q LL ES+ ESLK + LE VLKQ + + + E +EK + E + + +
Sbjct: 3654 NLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEE 3713
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIE--QKEVEERQRE 1703
Q+ + EY Q+++ ++++ D +Q+ K++E+ L+ I+ Q+E+E+ +
Sbjct: 3714 MTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQELEKEKEI 3773
Query: 1702 CMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSV---------------DFS 1568
M SE D+ + L+K+ + I ++N+ QL DF
Sbjct: 3774 IMKDRSEL--DLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFD 3831
Query: 1567 AG--VFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKS 1394
G E+ + + +E +N L ++++E + E R EE + + LE +
Sbjct: 3832 QGRNSLDEDLKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTE 3891
Query: 1393 QLETSNTMDHDTLSSTHQGSMEDKASSQSSTGD----NDPKAXXXXXXXXXXXECRQNL- 1229
+L+ + S TH ED Q + N+ E R+N+
Sbjct: 3892 ELK------REKESFTHLA--EDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENIS 3943
Query: 1228 -ENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNH 1052
+ E+ K+K+ E ++ + EL + ++ + + +++ I+K EDL
Sbjct: 3944 KQTEDVKNKK-ENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKI 4002
Query: 1051 GQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHAN 872
L + SLK+ ++ F EN ++ L K + + +LE +H
Sbjct: 4003 ISLDRDAESLKL---DREAF--------ENEREVLKQMKTELERETDEIEKIKLETQHDR 4051
Query: 871 MSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNME 692
+ ++ +I + ++ L+ + + KD + + + I S K+ML+ N+E
Sbjct: 4052 QRVEEMTAQITKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLE 4111
Query: 691 ASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINT 512
+ +S +++E L Q N E Q E + K E+I
Sbjct: 4112 KT----RSELYKVKEDLEKQKENTLAEI-------QKEREDL---------EKMNENITI 4151
Query: 511 EIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTK-LELLAKKTSEMD 371
E+ ++E++ + Q +++ L++ +Q L+Q+ K E++ K SE+D
Sbjct: 4152 EMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELD 4199
Score = 92.0 bits (227), Expect = 1e-15
Identities = 127/649 (19%), Positives = 278/649 (42%), Gaps = 43/649 (6%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSL 2060
D + ++ K++ D+ ET+KN + LD +++ +++ E+ + ++ +S L
Sbjct: 6195 DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKDL 6254
Query: 2059 KRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQANE--- 1898
K +K +Q E +++ E +K ELE + I +K+E + R +E + +EL + E
Sbjct: 6255 KMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFT 6314
Query: 1897 --------EVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQE 1742
E ++L K + L Q+ ++L ++ E+ S + +KK + ++
Sbjct: 6315 HLAEDTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLRED 6374
Query: 1741 VIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTL---SVDF 1571
+ Q + E +++ + + + + A+ K + + KI L+ D L L + +
Sbjct: 6375 ELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFEN 6434
Query: 1570 SAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKS 1394
V K+ T++ D +++I K+ Q R VEE ++ + K + + +
Sbjct: 6435 EREVLKQMKTELEREADEIEKI-----------KLETQHDRQRVEEMTAQIQKDRDKINN 6483
Query: 1393 QLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-- 1220
+E +N D L+ ++ + S QS + + + +++LE +
Sbjct: 6484 LIEETNRKDM-VLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKE 6542
Query: 1219 ----------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKE 1070
E K E E+ + MN + + L + L+ ++ K KE
Sbjct: 6543 NTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKE 6602
Query: 1069 DLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQL 890
++ QL S L + N M ++N +K+L KD+ + E Q + +
Sbjct: 6603 IIMKARSQLDRRQSELDKQQTNMNDIME----TMKNERKQL--DKDKEEMEE-QKQEMEK 6655
Query: 889 ELKHANMSICSLSEKIQQIEEREKVL---LTQLSTKDTDMQHLAAQLTLAQEEISSTKEM 719
E + + S SL E ++ ++ +++V+ +L +++ A + +EE + +++
Sbjct: 6656 ERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQI 6715
Query: 718 LKDFIDNME---------ASDTNLQSHFNQIQEM-LLNQNVNYPLEATVNIGFDQSMDEA 569
L+ + ++ A DT + N + EM + N++ L+ +++E
Sbjct: 6716 LEKMAEELKKERKDVAHLAEDTKREK--NSLDEMKVANESSMADLQKE-----KSNLEEM 6768
Query: 568 VSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
I +K TEDI E +++E+ +LQ+++ QS ++ K
Sbjct: 6769 KENI------SKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEK 6811
Score = 84.0 bits (206), Expect = 3e-13
Identities = 137/676 (20%), Positives = 281/676 (41%), Gaps = 48/676 (7%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDL-DIEQKLSTDRQSEIYSLS-AELER---ITQ 2078
L R DI+K E K ++ + +L D + +L DR + ++ EL+R + +
Sbjct: 9465 LQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRE 9524
Query: 2077 SEQMSLKRLKEAEQTLL---EAESERESLK-------------AELEESISVLKQELSSA 1946
+E + K L++ EQ + + E++ E+L+ A+ E++ +Q+L
Sbjct: 9525 TEDLERKILQQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLL 9584
Query: 1945 RLQIESLEKELNQA--NEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFD 1772
+ ++S E EL EE K L + + + E + ++S ++ +Y + +L
Sbjct: 9585 QGALQSQESELENRVFMEEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQR 9644
Query: 1771 KKNEITCLQEVIEQKEVE--------ERQRECMLAASERSNDINVNALEKKLSA---YEG 1625
+K ++ + IEQ++ + ERQ E + D NALEK S +
Sbjct: 9645 EKEQLEISKNQIEQEKKDLQNMKSNLERQLESLRHEKANVED-EKNALEKMRSESKEIQN 9703
Query: 1624 KIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARH 1445
IR+ D+ + ++ +EE+ ++ + ++++++ L++ R + ++ +
Sbjct: 9704 AIRKEREDLENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINN 9763
Query: 1444 NVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXX 1265
+EE + + K ++E + D E + D K
Sbjct: 9764 KMEELLQMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQE--- 9820
Query: 1264 XXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDI 1085
+ E K + +E K L E+ + + EM + +G +
Sbjct: 9821 ------------KEREIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLL 9868
Query: 1084 LKYKEDLLLNHGQLRAEMSSL---KIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAE 914
K K++L +L +M L K E E+ + +E+++KE I K++ + +
Sbjct: 9869 EKEKQELKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEK 9928
Query: 913 GQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTK-DTDMQHLAAQLTLAQEE- 740
+ QL++ L+++ ++ ++EK L Q + + Q L T EE
Sbjct: 9929 SNIEEMQLKIFKQQR----LNDQTREENKKEKESLEQQRFETEQQKQMLEISTTKMMEEK 9984
Query: 739 -----ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMD 575
+S + KD ++ + A TN + H + + L+ + +E I D+
Sbjct: 9985 NEMADLSRELQKAKDELEKI-AYKTNKERHEVEQMQAELHSQIQ-AIEQQGQIMQDKQNH 10042
Query: 574 EAVSEIAVQTFPNK---DTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTK- 407
E+++Q + + E H ++ EE K Q +E +++ +++ KQ+N K
Sbjct: 10043 LEEKELSIQRKEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQKNNKD 10102
Query: 406 LELLAKKTSEMDPEKY 359
ELL K SE++ EKY
Sbjct: 10103 FELLEKIRSELENEKY 10118
Score = 80.1 bits (196), Expect = 4e-12
Identities = 118/630 (18%), Positives = 261/630 (41%), Gaps = 10/630 (1%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
D+Q+EK I E+++E + D++ E++ S R+ E+ L E++ K+ E
Sbjct: 4344 DLQREKRILEEMRENISKQTEDIENEKEKSKLREDELKKLQTEVQ----------KQQSE 4393
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESL--EKEL--NQANEEVKVLSK 1877
+ ESER + E + ++ LK++ +Q++ + EKEL N +N K +
Sbjct: 4394 IDMEKTNIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMED 4453
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVE---ERQR 1706
+ +++ +E S+ L D E + L K ++ + IE+ ++E +RQR
Sbjct: 4454 LKQKLMSIERDSESLKLD----REAFGNEKEVLKQMKTDLQIQADEIEKIKLETQHDRQR 4509
Query: 1705 ECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNA 1526
A + + +N L + + + + ++ D+ + S+ + ++E +
Sbjct: 4510 VEEKTAQIQKDRDEINNLIVETNRKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLEKT 4569
Query: 1525 -CDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSS 1349
+L + EN + +E K I++ + N+ +KH E Q + + +
Sbjct: 4570 RSELARAKENLETQREIERK-DIEKMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQN 4628
Query: 1348 THQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAEL 1169
Q ++K + D + + + ++NE KQ+++ K E
Sbjct: 4629 LQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNER---KQLDKDK---EET 4682
Query: 1168 NNWLSCMNAEMGKFLCLCNSMVYLEGDI--LKYKEDLLLNHGQLRAEMSSLKIELVEKNG 995
M E F S L+ D+ +K ++ ++ + ++++ +KIEL +
Sbjct: 4683 EEQKQEMEKEKHDF---DQSRKSLDEDLKMMKLQKQVI---EEEKSKLKQMKIELEREAD 4736
Query: 994 FMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKV 815
++ V++E ++ I E ++A + E + + ++ + +++ +
Sbjct: 4737 -------EIRKVKEET---QNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANES 4786
Query: 814 LLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLN 635
L + + +++Q + ++ E++ + KE ++ E LQ+ ++ Q
Sbjct: 4787 TLADILRERSNLQEMRENISKQTEDVENKKEKIR----LREEKLKQLQAEIHKQQSETEK 4842
Query: 634 QNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQV 455
+ N E I KD ED+ ++I + D+D E +KL
Sbjct: 4843 EKSNIERERAAII--------------------KDVEDLQSKII-SLDRDAESLKLDR-- 4879
Query: 454 ENLQSLVQMLKQQNTKLELLAKKTSEMDPE 365
E ++ + LKQ T+LE A + ++ E
Sbjct: 4880 EAFENEKEELKQMKTELEREADEIEKIKLE 4909
Score = 79.7 bits (195), Expect = 5e-12
Identities = 122/685 (17%), Positives = 295/685 (43%), Gaps = 64/685 (9%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
+I+KEK KE + + + +I + T+R+ E+Y + +ELER+ K+L +
Sbjct: 11258 EIKKEKE-----KENEEEEEEEEEIRVIVETERK-ELYQIKSELERVRSEIDHEQKKLND 11311
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSA--RLQIESLEKELNQANEEV--KVLSK 1877
+ + + + + E +K+E+ + +++E S ++Q +LEK + ++E+ K++ +
Sbjct: 11312 YMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVE 11371
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECM 1697
Q +++ ++L + K+ ++ + ++ +NE +++V E+ +++RE +
Sbjct: 11372 VEEQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKKVDEE---IKKERETL 11428
Query: 1696 LAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDL 1517
R +I++ +++L + + +R + D+ +++ ++ E+ + N DL
Sbjct: 11429 -----REMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDIN-------EQKLHLKNQRDL 11476
Query: 1516 LQEIENFLREIRVETKVTIQEARHNVEEFSSVV--KHLEYLKSQLETSNTMDHDTLSSTH 1343
L+ + R E + + + ++EF + V + + K ++E +T +
Sbjct: 11477 LE-------QEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARII 11529
Query: 1342 QGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECK---SKQMEEYKMLQAE 1172
+ M+ KA Q + + + + EE + + EE +++E
Sbjct: 11530 E--MKTKAELQEIMQEKEEE------------------DEEEMRVIVEMEREELNQIKSE 11569
Query: 1171 LNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSL---------- 1022
L S ++ E K + + D+ K K +++ Q+ E S L
Sbjct: 11570 LKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLE 11629
Query: 1021 KIELVEKNGFMGYAVLDVENVQKELLIWK-----DRAMIAEGQSKAFQ--LELKHANMSI 863
+ ++ + ++ VE +K++ + K +R IA+ Q Q +L++ N I
Sbjct: 11630 RHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERI 11689
Query: 862 CSLSEKI---------------QQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISST 728
+ E+I ++ EE V+ K D++ ++ + +++ +
Sbjct: 11690 KEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDVNKQNQDLMNQ 11749
Query: 727 KEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEA---VSEI 557
+++LK + + T LQ ++ + Q + +S++E + E+
Sbjct: 11750 RDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEM 11809
Query: 556 AVQTFP-----NKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLV-----------QML 425
+T P K+ E+ A K EE+ +++SQ+E ++S + +M+
Sbjct: 11810 KTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMI 11869
Query: 424 KQQNTKLEL----LAKKTSEMDPEK 362
+Q+ LE + K+ +M+ E+
Sbjct: 11870 EQEKEDLEKMKSEIMKQRQQMEEER 11894
Score = 78.6 bits (192), Expect = 1e-11
Identities = 129/680 (18%), Positives = 300/680 (44%), Gaps = 61/680 (8%)
Frame = -2
Query: 2227 LDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++IQKE+ I E LK + + DL+ E+ +++I SLS +L+ ++ E + R +
Sbjct: 3114 VEIQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI-SLSEDLKEQSEREGIDNTRTR 3172
Query: 2047 ----------------------EAEQTLLEAESER-ESLKAELEESISVLKQELSSARLQ 1937
E ++ ++E E ++ E +KAEL++ K EL + R
Sbjct: 3173 IKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNERQN 3232
Query: 1936 IESLEKELNQANEEVKVLSK--FRYQV----LELEEYSQQLSADLSKVHEDYSAALRQLF 1775
+E +L + E V+ L++ R QV +++E Q+ + + +K ++ L +L
Sbjct: 3233 LEEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQE--RVLIELK 3290
Query: 1774 DKKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVS 1595
+I +E +E + +EER++ + A ++ + L++ +S + I N
Sbjct: 3291 KTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDI---VNKTE 3347
Query: 1594 QLTLS----VDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFS 1427
QL L A +++++ +N ++ E + L + E +E +E S
Sbjct: 3348 QLRLREVELEQLQALIYRQQDEIEANRKAIINE-KYRLEGQKTEIDRLQREVNQMMEYAS 3406
Query: 1426 SVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSS-TGDNDPKAXXXXXXXXXX 1250
+LE KS++ + D + +G +E++ ++ + D K
Sbjct: 3407 KDRANLEKEKSEM-IAQKHQMDIELNKERGLIEERTQMLNTYEKEMDQKRTALEVEMKEL 3465
Query: 1249 XECRQNLENEECKSKQM--------EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLE 1094
+Q ++ E+ K +QM ++ K L+ + N + + + +L
Sbjct: 3466 KYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLAHLA 3525
Query: 1093 GDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAE 914
D + +++ + H A++ K L + M +++ +K++++ +D+ +
Sbjct: 3526 EDTKRKDDEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQQMQ 3585
Query: 913 GQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEIS 734
+ Q E+ SI + + + ++ + L+T+L+ + D++ ++ +E +
Sbjct: 3586 AEINRQQTEM-DTKKSI--IENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLTEKELLE 3642
Query: 733 STKEMLKDFIDNMEASDTNLQS---HFNQIQEMLLNQ---------NVNYPLEATVNIGF 590
S +++LK ++N++ ++S Q +E+L N+ ++ E I
Sbjct: 3643 SDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKL 3702
Query: 589 D-----QSMDEAVSEIAV-QTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQM 428
+ Q ++E ++I + + K ++I EI +++++ + Q +++ L++ +Q
Sbjct: 3703 ETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQN 3762
Query: 427 LKQQNTK-LELLAKKTSEMD 371
L+Q+ K E++ K SE+D
Sbjct: 3763 LQQELEKEKEIIMKDRSELD 3782
Score = 78.6 bits (192), Expect = 1e-11
Identities = 131/650 (20%), Positives = 261/650 (40%), Gaps = 30/650 (4%)
Frame = -2
Query: 2245 TLDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQM 2066
T+ R + K+K +E+ K+ ++ + D D +K S
Sbjct: 4667 TMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRK---------------------SLDE 4705
Query: 2065 SLKRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQANEE 1895
LK +K +Q + E +S+ + +K ELE + I +K+E + R E + + L + E+
Sbjct: 4706 DLKMMKLQKQVIEEEKSKLKQMKIELEREADEIRKVKEETQNERQIFEKMTEALKKERED 4765
Query: 1894 VKVLSKFRYQVL-ELEEYSQQLSAD-------LSKVHEDYSAALRQLFDKKNEITCLQEV 1739
+ +K + QVL E++ ++ AD L ++ E+ S + +KK +I +E
Sbjct: 4766 LSEDAKRKNQVLDEMKVANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLREEK 4825
Query: 1738 IEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGV 1559
++Q + E +++ + + + A+ K + + KI L+ D L L +
Sbjct: 4826 LKQLQAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDRE----A 4881
Query: 1558 FKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETS 1379
F+ E ++ L+ + + +I++ET Q R VEE ++ +ET
Sbjct: 4882 FENEKEELKQMKTELEREADEIEKIKLET----QHERQRVEEMTA---------DFMETM 4928
Query: 1378 NTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQM 1199
N + L+ + E K + D D +Q +E E+ K +QM
Sbjct: 4929 NN-ERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQM 4987
Query: 1198 --------EEYKMLQAELNN---WLSCMNAEMGKFLCLCNSMVYLEGDI---LKYKEDLL 1061
+E + ++ E N L M E+ K S +L D K + +
Sbjct: 4988 KIELEKEADEIRKIKEETQNERQRLEKMTEELKKEK---ESFTHLAEDTKTEKKILDKMK 5044
Query: 1060 LNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELK 881
+ + L A++ K L E + D E ++++ + +D + + Q E+K
Sbjct: 5045 VANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQLQAEIHKQQGEIK 5104
Query: 880 HANMSICSLSEKIQQIEEREKVLLTQLSTKDT-DMQHLAAQLTLAQEEISSTKEMLKDFI 704
EK ER ++ KD D+QH L E + +E ++
Sbjct: 5105 ---------MEKSNNESERAAII------KDVKDLQHKMFSLDRDLESLKLDREAFENER 5149
Query: 703 DNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTE 524
+ ++ T+L+ +I+++ L + Q ++E ++I K+ +
Sbjct: 5150 EVLKQIKTDLKRKAEEIEKIKLETQHD-----------RQRVEEMTAQI------QKERD 5192
Query: 523 DINTEIAHTSDKD----EEVIKLQSQVENLQSLVQMLKQQNTKLELLAKK 386
IN I T+ KD E +++ +++ ++S ML+++ LE K
Sbjct: 5193 KINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSK 5242
Score = 76.3 bits (186), Expect = 5e-11
Identities = 150/706 (21%), Positives = 304/706 (43%), Gaps = 71/706 (10%)
Frame = -2
Query: 2233 VRLDIQKEKNISEDLKET-------VKNLQSDLDIEQKLSTD--------------RQSE 2117
+++++QK+KN E+L+ T V+N + LD +QK D +SE
Sbjct: 14325 LQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSE 14384
Query: 2116 IYSLSAELERITQSEQMSLKRLKEAEQTLLE-----AESERESLKAE------LEESISV 1970
+ LS L Q EQ L+RL E E+ +E ESE++S++ E L+E + V
Sbjct: 14385 LNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIESEKQSIERERAELKRLKEEVEV 14444
Query: 1969 ------LKQELSSARLQIESLEKELNQANEEVKVL-SKFRYQVLELEEYSQQLSADLSKV 1811
L+Q+ + + + E LE E + EE+ L + + + EL+ ++++ A K
Sbjct: 14445 QHERTLLQQDKNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEA---KR 14501
Query: 1810 HEDYSAALRQLFD----KKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKK 1643
E+ L + + K E L+E I +K+ + ++ L + R + +L++
Sbjct: 14502 QEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQ-TSLDEI 14560
Query: 1642 LSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREI-RVET-- 1472
E + R LE V+ + V K E T S ++ + N ++E+ R++T
Sbjct: 14561 TKTDERRQRALEETVA----TTAKQPIVIKLEDTLTSEVQEMRDHLNNEIKELARMKTIM 14616
Query: 1471 ---KVTIQEARHNV----EEFSSVVKHLEYLKSQLE---TSNTMDHDTLSSTHQGSMEDK 1322
K +++A+ ++ EEF ++ KS+ E T D + LS+T +
Sbjct: 14617 KMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLD---KKN 14673
Query: 1321 ASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNA 1142
+++T K + ++N+ENE + KQ+E+ + +Q + + ++
Sbjct: 14674 KEIENNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQIEQEREIQRKAD--VTSTEK 14731
Query: 1141 EMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVE- 965
EM Y E + YK +L + +++ + S +EL + + + +
Sbjct: 14732 EM-----------YTEK--VTYKTELEDSKEKIKPDRDS-TLELTDTDSAKTDGEREAQT 14777
Query: 964 ---NVQKELLIWKDRAMIAEGQSKAFQ------LELKHANMSICSLSEKIQQIEEREKVL 812
VQ L + D E + LEL A + L E+ + EE + V+
Sbjct: 14778 LETKVQDVLQLTDDTTQDQEELHDEMENKMKIILELNKAKKDLQKLKEECRSAEEEKSVI 14837
Query: 811 LTQLSTKDTDMQHLAAQ-LTLAQE--EISSTKEMLKDFIDNMEASDTNLQSHFNQIQEML 641
+ L + ++ + ++ L+L QE ++ K ++ M+ ++ + + ++
Sbjct: 14838 MESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWE--TDVQ 14895
Query: 640 LNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKD-EEVIKLQ 464
+ Q P+E T +I +S +E ++ Q K + + +E+ D + E+V +++
Sbjct: 14896 IQQEGQEPIETTGHI-TKKSEEEISAKKTKQPIVTKLEDTLTSEVQEMRDMEIEDVARMK 14954
Query: 463 SQVENLQSLVQMLKQQ-NTKLELLAKKTSEMDPEKYFHFEELCQSL 329
+ ++ + ++ K ++E + E EK + E L Q L
Sbjct: 14955 TMMKMEKDQLEQAKSDIQRQMEEFERNMEETLKEKSRNEETLLQLL 15000
Score = 75.9 bits (185), Expect = 7e-11
Identities = 131/629 (20%), Positives = 268/629 (42%), Gaps = 25/629 (3%)
Frame = -2
Query: 2227 LDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++IQKE+ I E LK + + DL+ E+ +++I SL ELE ++ E + R++
Sbjct: 2720 VEIQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI-SLREELEEQSEKEGIDKTRVR 2778
Query: 2047 EAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRY 1868
+Q + E E R ++ ELE + + KQ + R +IE ++ EL +E K K R
Sbjct: 2779 -IKQEMDELEQTRLNVVKELENN-ELQKQIIEDERDKIEQIKAEL---QKEAKDTEKQRQ 2833
Query: 1867 QVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIE------QKE------ 1724
+ ++++ L +D + ++ D++ + L++ +E +KE
Sbjct: 2834 DIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDLKK 2893
Query: 1723 --VEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
E + E L + R ++I + ++K+ E +L+ +S+ ++ F++
Sbjct: 2894 TNTEMKDLEKQLESQNRQHEIQLAEIQKEREILE----QLKLTLSKQKEDLEKERDCFEK 2949
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFS-SVVKHLEYLKSQLETSNT 1373
E +S +L ++ E RE +T+V I++ +++ +VVK LE +N
Sbjct: 2950 EKADISLREELQEQSE---REGIGKTRVRIKKEMDELKQTRLNVVKELE--------NNE 2998
Query: 1372 MDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEE 1193
+ + + KA Q D + + E L+NE+ K +
Sbjct: 2999 LQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEK-KDIETST 3057
Query: 1192 YKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIE 1013
++ E N + E + +++ D+ K K ++ QL +++ +I+
Sbjct: 3058 DRIRDEEANLEVQKQRLESDR-----DTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQ 3112
Query: 1012 LVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELK--HANMSICSLSEKIQ 839
LVE +QKE I + + Q + + E + SLSE ++
Sbjct: 3113 LVE--------------IQKEREILEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLK 3158
Query: 838 QIEEREKV--LLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSH 665
+ ERE + T++ + +++ L QE K++++D D +E L+
Sbjct: 3159 EQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKE 3218
Query: 664 FNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEI---AHTS 494
+ + L N+ N EA + D+ E+++E + + I TE+ A+ S
Sbjct: 3219 AEKTKLELQNERQNLE-EAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANES 3277
Query: 493 DK---DEEVIKLQSQVENLQSLVQMLKQQ 416
+K + +I+L+ V ++ + L+ Q
Sbjct: 3278 NKQMQERVLIELKKTVTDIAGAKEDLENQ 3306
Score = 75.9 bits (185), Expect = 7e-11
Identities = 137/684 (20%), Positives = 276/684 (40%), Gaps = 75/684 (10%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L ++ ++ KEK E++K+ VK + ++ E++ + + + I +
Sbjct: 9388 LQQMKNELNKEKEQVEEMKQMVKTERVKIEQEKE----------EMRKQTQEIEDGHEKL 9437
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVL 1883
K+ + A++ L +A SE + LK +L + + +Q++ ++E+ ++ L++ + E+
Sbjct: 9438 QKKTEIADKLLQDANSESDRLK-DLSMKLQMQRQDIEKTNTEMETKKRSLDRMSREL--- 9493
Query: 1882 SKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRE 1703
Q L + Y + L K+ E+ E +E+K +++R+++
Sbjct: 9494 --------------QDDKIRLKNDRDAYEKDMTHLELKREELVRETEDLERKILQQREQD 9539
Query: 1702 CMLAASERSNDINVNALE-------KKLSAYEGKIRRLENDVSQLTL--------SVDFS 1568
M ++R + ALE KK + + ++ + ++ +L L +
Sbjct: 9540 EM---AKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQESELE 9596
Query: 1567 AGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQL 1388
VF EE + A +E L E+ E R +EE + LE K+Q+
Sbjct: 9597 NRVFMEEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQREKEQLEISKNQI 9656
Query: 1387 ETSNTMDHDTLSSTHQGSME----DKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLEN- 1223
E D + S + +E +KA+ + + + R++LEN
Sbjct: 9657 E-QEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENC 9715
Query: 1222 ---EECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNH 1052
E + K+MEE + +++E+ K ++ E I E+LL
Sbjct: 9716 WVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSR---ENIESREEKINNKMEELL--- 9769
Query: 1051 GQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDR------AMIAEGQ------ 908
Q++ EM K E+ +++ + A +D+EN + E+ +D+ I E +
Sbjct: 9770 -QMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQ 9828
Query: 907 --------SKAFQLELKHANMSICSLSEKIQQIE------EREKVLLTQLSTK-DTDMQH 773
S+ +L++K M + + + Q+IE E+EK L Q + + M
Sbjct: 9829 LDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMD 9888
Query: 772 LAAQLTLAQEE---ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLL----NQNVN--- 623
L + +EE + + K L+D E L + I+EM L Q +N
Sbjct: 9889 LTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQT 9948
Query: 622 -----YPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTE--DINTEIAHTSDKDEEVI--- 473
E+ F+ + + EI+ + E D++ E+ D+ E++
Sbjct: 9949 REENKKEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDELEKIAYKT 10008
Query: 472 -KLQSQVENLQ----SLVQMLKQQ 416
K + +VE +Q S +Q ++QQ
Sbjct: 10009 NKERHEVEQMQAELHSQIQAIEQQ 10032
Score = 75.1 bits (183), Expect = 1e-10
Identities = 131/671 (19%), Positives = 280/671 (41%), Gaps = 33/671 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD ++ ++Q E E++K + +++++ EQ+ + I +LE + +
Sbjct: 10359 LDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGDLEIMRADYE-- 10416
Query: 2062 LKRLKEAEQTLLEAESERESL---KAELEESISVLKQELSSARLQIESLEKELNQANEEV 1892
K+ ++ E+ +EA+ ER+ L K+ELE+ + + E +EKE N
Sbjct: 10417 -KQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKERNDLE--- 10472
Query: 1891 KVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQ--KEVE 1718
K+ S+ Q ++E+ +L + + + + K++I +E++E+ EVE
Sbjct: 10473 KMKSELMTQRQQMEDERSELDQKIKEANTE-----------KDKIEKNKEIVERLMAEVE 10521
Query: 1717 ERQRECML----AASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
E++ + L A ER N ++ L L+ E +++ + + E
Sbjct: 10522 EQRNDFKLKKEELALERQNIVDEKYL---LAQCETELQNKSEQIRNM------------E 10566
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTM 1370
E+ K N + L+E E L+ + E K I+E E+ + + K +L+
Sbjct: 10567 EAVK--NERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKK-- 10622
Query: 1369 DHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEY 1190
DTL + Q + D + R+ E + K+MEE
Sbjct: 10623 --DTLEQEREEINHKWTQFQQRIDEFDAQV-------------RKQKEEDLTNQKKMEEE 10667
Query: 1189 KMLQAELNNWLSCMNA----EMGKFLCLCNSMVYLEGDILKYKED---LLLNHGQLRAEM 1031
+ E+N + M E + + L+ I+K KE + + R ++
Sbjct: 10668 RKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAMTIKLKMEREDL 10727
Query: 1030 SSLKIELVEKNGFMGYAVLDVENVQKEL-----LIWKDRAMIAEGQSKAFQLELKHANMS 866
+K ELV + +V++ QK+L +I +++ + + +S+ + +
Sbjct: 10728 DQIKSELVREK-------TEVDHEQKKLNDDIKMIEQEKEDLEKMKSE-IMTQKQEMEKE 10779
Query: 865 ICSLSEKIQQIE------EREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFI 704
L KIQQ + E+ K ++ +L + + +H ++ L +EE+ ++ + D
Sbjct: 10780 RSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRH---EIQLQKEELDIERQKIADEQ 10836
Query: 703 DNMEASDTNLQSHFNQIQEMLLNQNVNYPLEA--TVNIGFDQSMDEAVSEIAVQTFPNKD 530
D + + + LQ+ +I+ +N+ + E + ++ +E S +D
Sbjct: 10837 DLLIQNKSELQNENERIRN--INEVIKKERETLKEMEAHLEKEKEEMKSITEETRRQKED 10894
Query: 529 TEDINTEIAHTSDKDEEVIK----LQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEK 362
E ++T+I +++++++K L+ + E++ L+Q+ + + K E D K
Sbjct: 10895 LEKMSTDI---KEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQVSKQKEEDLTK 10951
Query: 361 YFHFEELCQSL 329
+E +SL
Sbjct: 10952 QKEMKEERKSL 10962
Score = 75.1 bits (183), Expect = 1e-10
Identities = 132/702 (18%), Positives = 287/702 (40%), Gaps = 68/702 (9%)
Frame = -2
Query: 2245 TLDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLST-------DRQSEIYSLSAELER 2087
TL + ++KEK + + E + + DL +K+ST D +S+ L E E
Sbjct: 12258 TLKEMEAYLEKEKEEMKSITEETRRQKEDL---EKMSTHINEQKQDLRSQRDLLEQEREE 12314
Query: 2086 ITQSEQMSLKRL--------KEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIE 1931
I + +R+ K+ E+ L + + +E K+ E ++L+ + + + E
Sbjct: 12315 INHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMK---TKAEPE 12371
Query: 1930 SLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITC 1751
++KE + EE ++ K + E+E Q+ + L +V + ++L D K I
Sbjct: 12372 EIKKEKEKEEEEQEMRVKVEMERKEIE----QIKSQLERVRSEMDHEQKKLNDDKKMIEQ 12427
Query: 1750 LQEVIE--QKEVEERQRECMLAASERSNDINVNALEK-KLSAYEGKIRRLENDVSQLTLS 1580
+E +E + E+ +++++ SE I LEK + + + +L +V +
Sbjct: 12428 EKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHE 12487
Query: 1579 VDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYL 1400
+ F E K+++ DLL ++ K+ Q ++E +K
Sbjct: 12488 IQFQKEELDIERQKIADEQDLL-----------IQNKIEQQNENERIKEMDEEIKKERET 12536
Query: 1399 KSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE 1220
++E + + + + S + + K + + D + + +Q+L N+
Sbjct: 12537 LKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQ--------------KQDLMNQ 12582
Query: 1219 ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGD-----------ILKYK 1073
KQ E E+N+ L+ + + +F N +V + + +K
Sbjct: 12583 RDLLKQERE------EMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEY 12636
Query: 1072 EDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQ 893
E ++ + R E+ ++++ ++N + +E +K+ K+R E Q +A
Sbjct: 12637 ESIIEETNRKRTELEEIEVDQSQQNKNVETMKDLLEKERKD--TEKER---EELQKQADD 12691
Query: 892 LELK------HANMSICSLSEKIQQIEEREKVLLTQ---LSTKDTDMQHLAAQLTLAQEE 740
LE++ MS SL E+ + +E++ +L Q L + DM +L Q+E
Sbjct: 12692 LEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKE 12751
Query: 739 ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSE 560
I + K +++ +E + +++E L N V + +++ + + E
Sbjct: 12752 IQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKHQQQ-IEE 12810
Query: 559 IAVQTFPNKDTED----------------------INTEIAHTS---DKDEEVIKLQSQ- 458
+ V+T +D D + E+ T D EE +KL+ Q
Sbjct: 12811 MRVKTKMERDELDQLMAKMLMDRKENERSKDMIGLLKKEMEQTKFNLDAQEEELKLEKQK 12870
Query: 457 VENLQSLVQM----LKQQNTKLELLAKKTSEMDPEKYFHFEE 344
++N + ++M +K++ ++++ L ++ E D + + +E
Sbjct: 12871 IQNEKKDLEMFKAEIKREASEVKTLKEQQLEKDTKAFEALKE 12912
Score = 75.1 bits (183), Expect = 1e-10
Identities = 125/644 (19%), Positives = 282/644 (43%), Gaps = 28/644 (4%)
Frame = -2
Query: 2218 QKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELE-RITQSEQMSLKRLKEA 2042
+KEK+ +++ ++++S ++ +L T+ ++I +++EL+ R + E + K+ KE
Sbjct: 13775 RKEKHAEAEIQRQFEDIES---VKVRLVTE-SNQIDKMNSELKTRSEELENLIKKQQKEF 13830
Query: 2041 EQTLLEAESERESLK---AELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFR 1871
E E + ER++L+ AELE + LK ++ + L+KE N+ E +L + +
Sbjct: 13831 ETKENEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREK 13890
Query: 1870 YQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-----TCLQEV-IEQKEVEERQ 1709
++ + + QQ ++ + + + + L +NE+ + L + +E+ E+++ +
Sbjct: 13891 SELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLK 13950
Query: 1708 RECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSN 1529
E + + + S + L++ E K +L+N + ++ + + +E+ +
Sbjct: 13951 TE--IQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMD---KLSIQREKDSLEEI 14005
Query: 1528 ACDLLQEIENFLREIRVETKVT--IQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTL 1355
DL ++ E E+R ++T I + +++ + L +++ +E + L
Sbjct: 14006 KADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQAKI----L 14061
Query: 1354 SSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSK-QMEEYKMLQ 1178
S Q +K + S +ND R++LE + ++ ++E + +
Sbjct: 14062 ESDVQLLQTEKEILEKSKTEND--------------LLREDLEKQRKRNDLTLQELRKEK 14107
Query: 1177 AELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKN 998
L ++ + E L N V L+ LK KE L + R EM L+++L +
Sbjct: 14108 MALEQMITDITKEKDAVASLQNE-VSLKQHELKNKETEL---DEQRKEMDDLRMQLEMRQ 14163
Query: 997 GFMG-----YAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELK----HANMSICSLSEK 845
V VEN++ + + ++ E + + Q +K N+ S ++
Sbjct: 14164 NSTNKQQQEVDVFIVENMKMRNDLESMKTLLDE-ERRQLQDNIKTFEDQKNVLHPSKTDA 14222
Query: 844 IQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSH 665
+QQ +E EK T + T+ ++ ++ + +EI +KE L+ +E +
Sbjct: 14223 VQQTDELEK-FTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGK 14281
Query: 664 FNQIQEMLLNQNVNYPLEATVNIGFD--QSMDEAVSEIAVQTFPNKDTEDINTEIAHTSD 491
QI+ + L A + G D +++ + ++A++ K ++ + +
Sbjct: 14282 RAQIESL-------EQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKN 14334
Query: 490 KDEEVIKL----QSQVENLQSLVQMLKQQNTKLELLAKKTSEMD 371
+ EE+ + QVEN + + + KQQ +++ SE D
Sbjct: 14335 ELEELRNTIEAEKHQVENRK--IMLDKQQKEVEDIMTVIKSERD 14376
Score = 72.8 bits (177), Expect = 6e-10
Identities = 145/702 (20%), Positives = 296/702 (42%), Gaps = 82/702 (11%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSE--------- 2072
+IQKE+ I E LK T+ + DL+ E+ +++I SL EL+ ++ E
Sbjct: 2918 EIQKEREILEQLKLTLSKQKEDLEKERDCFEKEKADI-SLREELQEQSEREGIGKTRVRI 2976
Query: 2071 --------QMSLKRLKEAEQTLLE---AESER---ESLKAELE---ESISVLKQELSSAR 1943
Q L +KE E L+ E ER E +KAEL+ E ++++ R
Sbjct: 2977 KKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDR 3036
Query: 1942 LQIESLEKELNQANEEVKV-LSKFRYQVLELEEYSQQLSAD-----------------LS 1817
E + +L ++++ + R + LE Q+L +D +
Sbjct: 3037 RNNEEMVIKLQNEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKERFDLEKTKTEMG 3096
Query: 1816 KVHEDYSAALRQLFDKKNEITCLQEVIE--------QKEVEERQRECMLAASERSNDINV 1661
+ + + +RQ + EI +E++E QKE E++R+C + DI++
Sbjct: 3097 NLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCF---EKEKADISL 3153
Query: 1660 NALEKKLSAYEGKIRRLENDVSQLTLSVD----FSAGVFKEESTK------VSNACDLLQ 1511
+ K+ S EG ++N +++ +D + KE+ + + D ++
Sbjct: 3154 SEDLKEQSEREG----IDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIE 3209
Query: 1510 EIENFLREIRVETKVTIQEARHNVEEFSSVVK----HLEYLKSQLETSNTMDHDTLSSTH 1343
+I+ L++ +TK+ +Q R N+EE + +K ++E L +L + + T
Sbjct: 3210 QIKAELKKEAEKTKLELQNERQNLEEAGTKLKKDRENVESLAEELGRKQVVLENMQIET- 3268
Query: 1342 QGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNN 1163
M+ KA ++S+ + +++LEN+ + + E+ K+ QAE+
Sbjct: 3269 --EMQRKA-NESNKQMQERVLIELKKTVTDIAGAKEDLENQLLEER--EKNKVKQAEI-- 3321
Query: 1162 WLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQL----------RAEMSSLKIE 1013
AE L + + DI+ E L L +L + E+ + +
Sbjct: 3322 -----QAEKDMLYLLKQGISEQQVDIVNKTEQLRLREVELEQLQALIYRQQDEIEANRKA 3376
Query: 1012 LVEKNGFMGYAVLDVENVQKEL-----LIWKDRAMIAEGQSKAFQLELKHANMSICSLSE 848
++ + + +++ +Q+E+ KDRA + + +S+ + KH M I L++
Sbjct: 3377 IINEKYRLEGQKTEIDRLQREVNQMMEYASKDRANLEKEKSE--MIAQKH-QMDI-ELNK 3432
Query: 847 KIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQS 668
+ IEER ++ L+T + +M L + +E+ K+ +++ + ++ LQ
Sbjct: 3433 ERGLIEERTQM----LNTYEKEMDQKRTALEVEMKELKYHKQAIQEEKNKLQQMKIELQR 3488
Query: 667 HFNQIQEML-LNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSD 491
+ I+++ +N LE ++ D+ ++ +A T D + E A +D
Sbjct: 3489 EADDIKKLKEKTRNERQSLEKMAE-NLEKEKDD-LAHLAEDTKRKDDEMKVLHESA-LAD 3545
Query: 490 KDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPE 365
+E L+ E++ +M+ + K+ L K +M E
Sbjct: 3546 IQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQQMQAE 3587
Score = 70.9 bits (172), Expect = 2e-09
Identities = 105/631 (16%), Positives = 253/631 (40%), Gaps = 12/631 (1%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L+ V +IQ+EK + + + +L+ + +RQ +I + +LE E+
Sbjct: 10166 LNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLE-----EEKL 10220
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEES-ISVLKQELSSARLQIESLE---KELNQANEE 1895
L +++ + E +R+ K E+ E+ + V+K++ +AR + E + +E Q NE
Sbjct: 10221 LVQIEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNEN 10280
Query: 1894 VKVL-----SKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-TCLQEVIE 1733
K L Q EL++ + L + E+ + R L ++K + E++
Sbjct: 10281 AKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILR 10340
Query: 1732 QKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFK 1553
Q++ E+++E M+ KL + +++ + ++ +D
Sbjct: 10341 QRDDLEKEKEDMMKK------------WNKLDVLQNEMQNENKAMEEIKYELDGKRNEIN 10388
Query: 1552 EESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNT 1373
+E ++ + + E + L +R + + Q+ E K L+ +KS+LE T
Sbjct: 10389 KEQQRLEESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKT 10448
Query: 1372 -MDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQME 1196
+D++ + +M +K + ++ RQ +E+E
Sbjct: 10449 EIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQ------------RQQMEDE-------- 10488
Query: 1195 EYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKI 1016
++EL+ + N E K + L ++ + + D L +L E +
Sbjct: 10489 -----RSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQRNDFKLKKEELALERQN--- 10540
Query: 1015 ELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQ 836
+V++ + +++N +++ + + +K+ ++ +Q+
Sbjct: 10541 -IVDEKYLLAQCETELQNKSEQI--------------RNMEEAVKNERETLKETEAHLQR 10585
Query: 835 IEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQ 656
++ K ++ + S + D++ ++ + + ++E+ + K+ L+ + + T Q ++
Sbjct: 10586 DKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDE 10645
Query: 655 IQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDE-E 479
+ Q ++ + M+E K E++N +I K E E
Sbjct: 10646 FDAQVRKQKEE-------DLTNQKKMEE----------ERKCLEEVNGKIIEMKTKAELE 10688
Query: 478 VIKLQSQVENLQSLVQMLKQQNTKLELLAKK 386
++ ++E LQ+L + + ++ K E + K
Sbjct: 10689 HHEINQKIEELQTLQEQIMKEKEKAEAMTIK 10719
Score = 70.5 bits (171), Expect = 3e-09
Identities = 135/717 (18%), Positives = 295/717 (41%), Gaps = 94/717 (13%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKETVKNLQSD-------LDIEQKLSTDRQSEIYSLSAELERIT 2081
D R DI+ K I + L V+ + D LDIE++ D Q + A+L+
Sbjct: 11905 DLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNEN 11964
Query: 2080 QSEQMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQAN 1901
+ + + +K+ ++TL E E+ L+ E EE SV+++ + +E + ++N+ N
Sbjct: 11965 ERIKEMDEEIKKEKETLKEMEAH---LRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQN 12021
Query: 1900 EEV----KVLSKFRYQV----LELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQ 1745
+++ +L + R ++ +L++ + A +SK E+ +++ +++ + +
Sbjct: 12022 QDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETK 12081
Query: 1744 -EVIE----------QKEVEERQRECMLAASERSND-------------INVNALEKKLS 1637
++IE +KE E+ + E M A E + ++ +KKL+
Sbjct: 12082 IKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLN 12141
Query: 1636 AYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSN--------ACDLLQEIENFLREIR 1481
+ I + + D+ ++ + +EE +++ N CD IEN +EI
Sbjct: 12142 DDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCD----IEN-SKEIV 12196
Query: 1480 VETKVTIQEARHNVE--------EFSSVVKHLEYL---KSQLETSN----------TMDH 1364
+ V ++E +H ++ E + + L KS+L+ N +
Sbjct: 12197 QKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKER 12256
Query: 1363 DTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEE--- 1193
+TL ++K +S T + + E +Q+L ++ +Q E
Sbjct: 12257 ETLKEMEAYLEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEIN 12316
Query: 1192 --YKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLK 1019
+K LQ ++ + + ++ + + L M + + K ++L + +AE +K
Sbjct: 12317 HKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANIL--EMKTKAEPEEIK 12374
Query: 1018 IELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQ 839
E EK + VE +KE+ K + + Q +L I E ++
Sbjct: 12375 KE-KEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLE 12433
Query: 838 QIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFN 659
+++ Q+ + +++ Q L + +I ++KE+++ + +E +Q
Sbjct: 12434 KMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKE 12493
Query: 658 QI----------QEMLLNQNVNYPLEATVNIGFDQSMD---EAVSEIAVQTFPNKDTEDI 518
++ Q++L+ + E D+ + E + E+ V K+ E+I
Sbjct: 12494 ELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNL--QKEKEEI 12551
Query: 517 NTEIAHTSDKDEEVIKLQS----QVENLQSLVQMLKQQ----NTKLELLAKKTSEMD 371
+ I T + E++ K+ + Q ++L + +LKQ+ N KL L ++ E +
Sbjct: 12552 ESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFE 12608
Score = 67.4 bits (163), Expect = 3e-08
Identities = 132/650 (20%), Positives = 266/650 (40%), Gaps = 34/650 (5%)
Frame = -2
Query: 2224 DIQKEK-NISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
+I EK NI + ++ Q+ + +K S D + ++ + E E + + K ++
Sbjct: 7066 EIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVE 7125
Query: 2047 EAEQTLLEAESERESLKAE---LEESISVLKQELSSARLQIESLEK-ELNQANEEVKVLS 1880
+ +Q L+ E + ESLK + E +KQ + ++Q + +EK +L +E +V
Sbjct: 7126 DLQQKLMSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRV-- 7183
Query: 1879 KFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-TCLQEVIEQKEVEERQRE 1703
++ +A + K E+ + + ++ K++ I E+ ++KE E R
Sbjct: 7184 -------------EEKTAQIQKEREEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRS 7230
Query: 1702 CMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNAC 1523
+ A ++ N N +E L+ + K LE +S + S K E
Sbjct: 7231 DLEKAKSQTFKQNKN-IEIALAEIQQKRNALEK------MSKEISRDRMKLE-------- 7275
Query: 1522 DLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTH 1343
+ K IQ AR +E ++ + K L S D L +
Sbjct: 7276 ---------------DEKKEIQLAREELERMHGDMQRQQEAKDHL-LSGITDESLLKKSE 7319
Query: 1342 -----QGSMEDKA----SSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEEC-------- 1214
Q S DKA ++ S D P +++ E+E+
Sbjct: 7320 AEIVLQPSQVDKAKPARKTEISDSDKQPVFVQQMPEMDLKDALKKDFESEKLDLPKVKDV 7379
Query: 1213 --KSKQME-EYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQL 1043
+ +QM+ E K+++ E++ L M AE+ K E D ++ K+ + N Q
Sbjct: 7380 LPQDQQMKLEQKLIEDEMDK-LKQMRAELQK-----------EADQIEKKKQDMQNERQK 7427
Query: 1042 RAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLE---LKHAN 872
+M++ E N E + +E+ I K + + Q+ AFQ+E +
Sbjct: 7428 LDDMAARLQEERRTN----------ERLNEEINIQK---VNQQKQATAFQMEKTDFERIK 7474
Query: 871 MSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNME 692
I ++++ +E+ K +T++ + ++ + A ++ E I++ + L
Sbjct: 7475 TEIDQANKELADQQEKNKKTITEMQKERETLEEMRANISKQVETITNENKSL-------- 7526
Query: 691 ASDTNLQSHFNQIQEMLLNQNVNY-PLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDI- 518
++ +S ++QE +L Q L+ T+ + Q +D+ S+I + K+ +D+
Sbjct: 7527 ---SSRESELAKLQEDILQQQQEMDELKNTIMMEMCQ-LDQRQSDIDLL---QKEVDDLM 7579
Query: 517 ---NTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSE 377
TE+A+ + E +++ +Q N++S + LK + E L K +E
Sbjct: 7580 DFTKTEMANV---ERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNE 7626
Score = 67.0 bits (162), Expect = 3e-08
Identities = 116/631 (18%), Positives = 263/631 (41%), Gaps = 25/631 (3%)
Frame = -2
Query: 2188 KETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTLLEAESER 2009
+E + +++++DIE+ + + ELE+I Q +AE E
Sbjct: 13384 REELAKMKTEIDIERDEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQHDEIHGGI 13443
Query: 2008 ESLKAELEESISVLKQELSSARLQIESLEKELNQANEEV-KVLSKFRYQVLELE--EYSQ 1838
+SLK E EE I +K +L + + E++ + + +E+ K ++ +E E + +
Sbjct: 13444 DSLKEEREE-IEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDK 13502
Query: 1837 QLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVN 1658
L ++ K+ A L+ +KN + + E + +E E + C + E++ ++N
Sbjct: 13503 NLQDEMMKI----EAILKVTKKQKNYLEQMNENL-TREKTELETNCQMLEREKT-ELNKK 13556
Query: 1657 ALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRV 1478
E + + K+ E + + +D A EE K+ +E+ N EI+
Sbjct: 13557 VKETE-EFHMSKMEEREAERKTIERVMDEMA----EEHEKIKKE---REELVNMEEEIKK 13608
Query: 1477 ETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTG 1298
+ +V ++ E + L++ +S+L D ++S + ++ + S Q
Sbjct: 13609 QRRV----LEESMNEMTKKKSELQHERSELYKQKQQLEDMIASESKRDVDTERSRQDKED 13664
Query: 1297 DNDPKAXXXXXXXXXXXECRQNLENEECK---SKQMEEYKMLQAELNNWLSCMNAEMGKF 1127
+ K ++ + E K +++ E + +Q++LN+ M+ E K
Sbjct: 13665 EQILKREREEIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKL 13724
Query: 1126 LCL-------CNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDV 968
L + N++ + D+ K +E++ Q + E I + E +A ++
Sbjct: 13725 LYMKTEIQVKTNALEKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEI 13784
Query: 967 ENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKD 788
+ +++ K R + Q ELK + SE+++ + ++++ + TK+
Sbjct: 13785 QRQFEDIESVKVRLVTESNQIDKMNSELK-------TRSEELENLIKKQQ---KEFETKE 13834
Query: 787 TDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEM--LLNQNVNYPL 614
+MQ L E+ LK+ I+ + + +LQ N+ +E+ +L + +
Sbjct: 13835 NEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREKSELY 13894
Query: 613 EATVNIGFDQSMDEAVSEIA------VQTFPNKDTEDINTEIAHTSDKDEEVIKL----Q 464
+ + + E + + ++ N+ ++ + ++ S + E+ KL Q
Sbjct: 13895 QEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTEIQ 13954
Query: 463 SQVENLQSLVQMLKQQNTKLELLAKKTSEMD 371
S+ E+++ + LKQ + E K +++D
Sbjct: 13955 SEKESIEEEKKTLKQLKDENE---SKRTQLD 13982
Score = 65.9 bits (159), Expect = 7e-08
Identities = 135/678 (19%), Positives = 282/678 (41%), Gaps = 63/678 (9%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKE-------TVKNLQSDLDIEQKLSTDRQSEIYSLSAELERIT 2081
D + I KEK S ++E T + + +++ E++ RQ E+ E+ERI
Sbjct: 546 DVEKAKILKEKEESIRIREEARQERETTELVNAEIKAEKERLNQRQEEMLRERQEIERIK 605
Query: 2080 QSEQMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQAN 1901
+ + ++ ++ + + E +KAE++ I +++++ + E +E+ +
Sbjct: 606 HETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKEQMEEAKVELE 665
Query: 1900 EEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITC---------- 1751
EE + L + R V E ++ L ++ +V E+ + R+ ++ E+
Sbjct: 666 EEREDLERKRDLVSREIEQAEFLRNEILRVKEEMESRWRETETEEVELRAKTQHELERLE 725
Query: 1750 -LQEVIE--QKEVEERQRECML-------AASERSNDINVNALEKKLSAYEGKIRRLEND 1601
L+E E QK +EE + E ML E D +V ++ ++ + K +L
Sbjct: 726 KLREETERSQKNIEESKIELMLWKESLDKLKGEMEEDKHVVIMQ--MNEAKAKEEQLTMV 783
Query: 1600 VSQLTL---SVDFSAGVFKEESTKVSNACDLLQ----EIENFLREIRVETKVTIQEARHN 1442
+ QL + + S KEE +++ + LQ E+E++ R + E K A+
Sbjct: 784 IEQLEIERGEITISREKVKEELDEINRMRNELQRQHAEMEDWFRVVNKE-KEEANLAKLA 842
Query: 1441 VEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXX 1262
V E + LK Q+E S ++ ++ ++E + Q KA
Sbjct: 843 VHEAEML------LKKQMEESEKRRYEMITE----ALEQRDEIQK-------KAEELEQI 885
Query: 1261 XXXXXECRQNLE-----NEECKSKQME---EYKMLQAELNNWLSCMNAEMGKFLCLCNS- 1109
RQ LE +E K +E + ++ ++ + L A+ K L +S
Sbjct: 886 NKEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLFEMDSE 945
Query: 1108 ---MVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLI- 941
+ + + K+DL Q R EM VE++ + ++E ++ +L+I
Sbjct: 946 RKELEQMRFQVENEKKDL----EQRRYEMMRYD---VEQSAQVQRQKEELEKIKSQLVID 998
Query: 940 ----WKDRAMIAEGQSKAFQL--ELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDM 779
+ R + + + KA L E++ + E+ +Q EE ++L + + D+
Sbjct: 999 TESMNRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRLLRKDMENEREDL 1058
Query: 778 QHLAAQLTL--------AQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVN 623
+ + + TL +EEI+ + ++ D E D + N +E ++ +
Sbjct: 1059 EKIRVE-TLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRK--- 1114
Query: 622 YPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIK--LQSQVEN 449
+EA + M E + ++ V+ K+ D+ E A + E++K L Q E+
Sbjct: 1115 --MEA-----MKREMGE-IEDMKVELTKQKENIDMKMEHARLEMTNLEMMKADLLRQKED 1166
Query: 448 LQSLVQMLKQQNTKLELL 395
+++ + K + ++E++
Sbjct: 1167 IENQMLAAKSERQQMEVM 1184
Score = 65.5 bits (158), Expect = 1e-07
Identities = 142/774 (18%), Positives = 319/774 (41%), Gaps = 66/774 (8%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
+++ ++ + ED K ++N++ +L E + ++ +E + + + L++
Sbjct: 1805 NLEAQRKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEK 1864
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQ 1865
+ + ++ER +LE + + L+ + + + LEK +++ N + K +
Sbjct: 1865 KRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEK-ISELNSQQKDEIENEKS 1923
Query: 1864 VLELEEYS-QQLSADLSKVHEDYSAALRQLFDKKNEITCLQ-EVIEQ-KEVEERQRECML 1694
+++ EY QQ+ DL++ ++ +F +K+E+ Q E+ EQ K+V + +
Sbjct: 1924 KIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQDEIAEQLKQVGDMMQ---F 1980
Query: 1693 AASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLL 1514
+E+ N L+++ +A + ++E D++ L S + K+E V N LL
Sbjct: 1981 TQNEKDN------LDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKE---VLNEKRLL 2031
Query: 1513 QEIE-NFLREIR--VETKVTIQEARHNVE-EFSSVVKHLEYLKSQLET----SNTMDHDT 1358
++ + +R+++ + K+ ++ + ++ + S+ + + L+S L+T + + DT
Sbjct: 2032 EDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDT 2091
Query: 1357 LSSTHQGSMEDKA---------------SSQSSTGDNDPKAXXXXXXXXXXXECRQNLEN 1223
L+ + +ED A ++ D D + + +L+
Sbjct: 2092 LAEKQK--LEDAAVELQKERDEIMNIAEETKRKREDVDKIRVGIEKQEITFKDLKADLQK 2149
Query: 1222 E--------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKED 1067
E + K ++ K ++ ++ M+ + + ++ ++ ++ K +++
Sbjct: 2150 EAAIVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVDKERQE 2209
Query: 1066 LLLNHGQLRAEMSSLKIE------LVEKNGFMGYAV--------LDVENVQKELLIWKDR 929
+ +L E S L+ + EKN + + L EN+ KE I
Sbjct: 2210 VESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTI---- 2265
Query: 928 AMIAEGQSKAFQLELKHANMSICSLSEKIQQIEE------REKVLLTQLSTKDTDMQHLA 767
F+LE +H + K +QI+E EKV + Q+ D D Q
Sbjct: 2266 ----------FELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQA-DKDQQRKK 2314
Query: 766 AQL--------TLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLE 611
A+ T A EE E L++ +N+E + H N+ +E+ ++ + +E
Sbjct: 2315 AEYVKTARGRETTALEEQRQEMESLREEYENVEKQ----KKHVNEQKELFESRMKSLEME 2370
Query: 610 ATVNIGFDQSMDEAVSEIAVQ-TFPNKDTEDINTEIAHTSDKDEEVIK-LQSQVENLQSL 437
+ + +D+ ++ Q K+ + + TE+ ++ E K L+ Q + +
Sbjct: 2371 NEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTE 2430
Query: 436 VQMLKQQNTKLELLAKKTSEMDPEKYFHFEELCQSLVXXXXXXXXXXXXXXXKNQVLVKQ 257
ML+ Q +E KT E+D + +L S V + + VK+
Sbjct: 2431 TYMLETQKPVVE--KSKTDELDEVRKKINADL--SEVEKQKSALVQMNLKISQEESYVKK 2486
Query: 256 VKEMQVTLQSESPMEGETDSISENAIGSQPA--GKLSTELHNVHGNTERVPLQL 101
K+ ++E M+ + +N + + A K EL NV E+ +++
Sbjct: 2487 EKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEI 2540
Score = 65.5 bits (158), Expect = 1e-07
Identities = 135/673 (20%), Positives = 272/673 (40%), Gaps = 57/673 (8%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQ--------KLSTDR---QSEIYSLSAELERITQ 2078
D+QKEKN +E+LK ++ +S+L E+ ++ T R +SE+ +L +
Sbjct: 13871 DLQKEKNKTEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELED 13930
Query: 2077 SEQMSLKRLK----EAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELN 1910
++ L RL E ++ E +SE+ES++ E ++++ LK E S R Q+++ +++N
Sbjct: 13931 EKKSMLSRLSMEKHEIDKLKTEIQSEKESIEEE-KKTLKQLKDENESKRTQLDNTIEKMN 13989
Query: 1909 ----------QANEEVKVLSKFRYQVLELE-----EYSQQLSADLSKVHED--------- 1802
+ EE+K + + + L+ E + + Q+S D + +D
Sbjct: 13990 MDKLSIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRS 14049
Query: 1801 -YSAALRQLFDKKNEITCLQ---EVIEQKEVEERQRECMLAASERSNDINVNALEKKLSA 1634
+ RQ ++++ LQ E++E+ + E L + ND+ + L K+ A
Sbjct: 14050 MRADIERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEKQRKRNDLTLQELRKEKMA 14109
Query: 1633 YEGKIRRLEND---VSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVT 1463
E I + + V+ L V K + T++ + ++ L + T
Sbjct: 14110 LEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQ 14169
Query: 1462 IQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPK 1283
QE + E + LE +K+ L+ D + + S + D
Sbjct: 14170 QQEVDVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDEL 14229
Query: 1282 AXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMV 1103
+ E + +K++ + K LN + E+ S+
Sbjct: 14230 EKFTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLE 14289
Query: 1102 YLEGDILKYKED---LLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWK- 935
L D+L +D L+ Q+ E + K E VE + ++E ++ + K
Sbjct: 14290 QLRADLLAGADDIKTLVQTEKQMAIEDTEKKTE-VELQMNLQKQKNELEELRNTIEAEKH 14348
Query: 934 ---DRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAA 764
+R ++ + Q K + I ++ + + + E+EK L +LS L
Sbjct: 14349 QVENRKIMLDKQQKEVE--------DIMTVIKSERDVLEKEKSELNKLS------HVLNE 14394
Query: 763 QLTLAQEEISSTKEMLKDFIDN----MEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNI 596
++ QEE+ E +D I+N +E+ +++ +++ L + V E T+ +
Sbjct: 14395 KVQREQEELERLLEKERDDIENCKKIIESEKQSIERERAELKR--LKEEVEVQHERTL-L 14451
Query: 595 GFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQ 416
D++M + K+ E + E A T+ EE+ L+ +++ S + ML +
Sbjct: 14452 QQDKNMIQ------------KEKEHLEGEKARTT---EEIHNLKEEIKRKSSELDMLNK- 14495
Query: 415 NTKLELLAKKTSE 377
E+ AK+ E
Sbjct: 14496 ----EIEAKRQEE 14504
Score = 64.7 bits (156), Expect = 2e-07
Identities = 117/652 (17%), Positives = 266/652 (40%), Gaps = 26/652 (3%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L+ + D+QK K +E + L+ + QSE+ SL+ E++ + Q +
Sbjct: 14813 LNKAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIK--- 14869
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVL---KQELSSARLQIESLEKELNQANEEV 1892
E +Q ++ + + S+ + E + + ++ + + + E+E++ +
Sbjct: 14870 ----TEMQQIEIKMQIQTRSVATQWETDVQIQQEGQEPIETTGHITKKSEEEISAKKTKQ 14925
Query: 1891 KVLSKFRYQVL-ELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVE- 1718
+++K + E++E D++++ QL K++I E E+ E
Sbjct: 14926 PIVTKLEDTLTSEVQEMRDMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEET 14985
Query: 1717 ----ERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
R E +L +D++ N L++K E + +++QL ++ + K+
Sbjct: 14986 LKEKSRNEETLLQLLHDKDDLS-NTLDEKSKEIENITVTFKRNIAQLETTI----AMMKK 15040
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTM 1370
+ + N L++ E REI+ T T E E + V + L+ E
Sbjct: 15041 DKENIENELLQLKQTEQ-EREIQRGTDDTSNER----ENYDEKVTYKTELEDSKEKKKPD 15095
Query: 1369 DHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-ECKSKQMEE 1193
+L T S + ++ T + K + ++ L +E E K K + E
Sbjct: 15096 RDSSLKLTDADSAKTDGEREAQT--LETKVQDVLQLTDYTTQDQEELHDEMENKMKIILE 15153
Query: 1192 YKMLQAELNNWL-SCMNAEMGKFLCL------CNSMVYLEGDILKYKEDLLLNH-GQLRA 1037
+ +L C +AE K + + NS+ ++ ++L ++ ++H Q++
Sbjct: 15154 LNEAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQE--IDHLAQIKT 15211
Query: 1036 EMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICS 857
EM ++I++ + +V + W+ I +GQ E I
Sbjct: 15212 EMQQIEIKM----------QIQTRSVATQ---WETDVQIQQGQ------EATETTGHITK 15252
Query: 856 LSEKIQQIEEREKVLLTQL-STKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDT 680
SE+ ++ ++ +T+L T +++Q + L E+++ K ++K D +E + +
Sbjct: 15253 KSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVARMKTIMKMEKDQLEQAKS 15312
Query: 679 NLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAH 500
++Q+ + F+++M+EA+ E + ++++
Sbjct: 15313 DIQTQMEE---------------------FERNMEEAMEEKSRNEEKLLQLTHDKEDLSN 15351
Query: 499 TSDKDEEVIKLQSQ-----VENLQSLVQMLK--QQNTKLELLAKKTSEMDPE 365
T DK + I+ ++ + L++ + ++K ++N + ELL K +E + E
Sbjct: 15352 TLDKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQERE 15403
Score = 63.9 bits (154), Expect = 3e-07
Identities = 125/676 (18%), Positives = 275/676 (40%), Gaps = 49/676 (7%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDL-------KETVKNLQSDLDIEQKLSTDRQSEIYSL-SAELER 2087
++ + D+Q E+ +D+ + T + L +++I QK++ +Q+ + + + ER
Sbjct: 7414 IEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINI-QKVNQQKQATAFQMEKTDFER 7472
Query: 2086 ITQSEQMSLKRLKEAEQ----TLLEAESERESLKAELEESISVLKQELSSARLQIESLEK 1919
I + K L + ++ T+ E + ERE+L+ E+ +IS + +++ + S E
Sbjct: 7473 IKTEIDQANKELADQQEKNKKTITEMQKERETLE-EMRANISKQVETITNENKSLSSRES 7531
Query: 1918 ELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEV 1739
EL + E++ Q E++E + ++ QL ++++I LQ+
Sbjct: 7532 ELAKLQEDI------LQQQQEMDELKNTIMMEMC-----------QLDQRQSDIDLLQKE 7574
Query: 1738 I---------EQKEVEERQRECMLAASERSNDINVNALEK------KLSAYEGKIRRLEN 1604
+ E VE + E + +D+ +EK +L E K +E
Sbjct: 7575 VDDLMDFTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNEEK-DLIEK 7633
Query: 1603 DVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS 1424
+ LT ++D + + ++ N + I+N +E+ + K+++Q +EFS
Sbjct: 7634 ERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKELE-KMKISLQRKAIGFKEFSE 7692
Query: 1423 VVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXE 1244
K + ++ T D +G ++ Q+ + K E
Sbjct: 7693 KTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQT-----EKKRRKTYYTEDLFQE 7747
Query: 1243 CRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL 1064
+ +L+ K EE + E+ + +N E + S + +I K KE +
Sbjct: 7748 EKTDLQ------KTKEEINYDREEIYRQRTELNKEKETLKQMHTSNLKEIENIEKEKEKI 7801
Query: 1063 LLNHG---QLRAEMSSLKIELVEKNGFM----GYAVLDVENVQKELLIWKDRAMIAEGQS 905
Q+RAE+ + + ++ + M D+EN+Q E KD +
Sbjct: 7802 QRTWNELDQIRAELQNKQRDMDDTTNIMMKEKAELARDLENLQNE----KDELQKSRENI 7857
Query: 904 KAFQLELKHANMSIC-SLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISST 728
+ EL+ + +L+++ QQ E ++ K+ + + A++ + + +
Sbjct: 7858 QKLMKELQEERLKTSEALNKERQQFTE-------EIKLKNDSLDEIQAEIDRQKRALVTD 7910
Query: 727 KEML-KDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNI-----GFDQSMDEAV 566
KE++ K +D + D QS + I L + + +V I ++ DE +
Sbjct: 7911 KEIITKQMMDLQKTQDVRRQSDESDIARANLQRERESLDQLSVEILKQKQDLERERDELL 7970
Query: 565 SE---IAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQ-----VENLQSLVQMLKQQNT 410
+ + Q N++ + + TE+ + E++ K Q EN +L + L++ N
Sbjct: 7971 EQWRLVETQKMDNENVKQLKTELLDEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNL 8030
Query: 409 KLELLAKKTSEMDPEK 362
+ + + + ++++ K
Sbjct: 8031 QKQGIQDERAQLERMK 8046
Score = 63.9 bits (154), Expect = 3e-07
Identities = 130/706 (18%), Positives = 276/706 (39%), Gaps = 79/706 (11%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLD--------IEQKLSTDR------------- 2126
++ +R DI +EKN ++ +SDL+ +Q + +R
Sbjct: 13100 IEKIRQDIDREKN-------DLEKYRSDLEKQYEEMEICKQNIENERAELEIDLENIIIE 13152
Query: 2125 ----QSEIYSLSAELE---------------RITQSEQMSLKRLKEAEQTLLEAESERES 2003
Q + S+ +L+ R + + + K +E EQ E E++
Sbjct: 13153 TKSKQERLESIEVQLQEKNVQMGTILDELNKRQEELDAIKAKTQREKEQMGHTEELEKDE 13212
Query: 2002 LKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSAD 1823
L A L++ ++K+ + + Q E L+KE +Q L K + LE+E + L+++
Sbjct: 13213 LIAILQKREEIVKRHMEEIQNQREELQKEKDQFGNMQAELQKGQ---LEMEMHQLMLNSE 13269
Query: 1822 ----------LSKVHEDYSAALRQLFDKKNEITCLQEVI-EQKEVEERQRECMLAASERS 1676
L K E++ + L ++ E + L++++ E+K VEE M A +
Sbjct: 13270 RDELNGMRVNLEKQKEEFELMQQNLESRRPE-SLLEDILKEKKRVEE-----MAAQLSKE 13323
Query: 1675 NDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDL----LQE 1508
+ N + + + E KI+++E ++ + + + ++E + N + LQ
Sbjct: 13324 QEEFRNIMSETIKRME-KIKQIEGEIKTKQIEMACLEELKQKELDEQKNMRECENQELQM 13382
Query: 1507 IENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSN------TMDHDTLSST 1346
L +++ E + E + +++ LE +K L+ + HD +
Sbjct: 13383 RREELAKMKTEIDIERDEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQHDEIHGG 13442
Query: 1345 HQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELN 1166
E++ + D K + LE +E + +QM ++ E N
Sbjct: 13443 IDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQM----AVETEDN 13498
Query: 1165 NWLSCMNAEMGKFLCLC-------NSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELV 1007
+ + EM K + N + + ++ + K +L N L E + L ++
Sbjct: 13499 DSDKNLQDEMMKIEAILKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNKKVK 13558
Query: 1006 EKNGFMGYAVLDVENVQKELLIWKDRAM--IAEGQSKAFQLELKHANMSICSLSEKIQQI 833
E F + + E +K + +R M +AE K +K + ++ E+I++
Sbjct: 13559 ETEEFHMSKMEEREAERKTI----ERVMDEMAEEHEK-----IKKEREELVNMEEEIKKQ 13609
Query: 832 EEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQ-SHFNQ 656
+ + +++ K +++QH + E+ K+ L+D I + D + + S ++
Sbjct: 13610 RRVLEESMNEMTKKKSELQH-------ERSELYKQKQQLEDMIASESKRDVDTERSRQDK 13662
Query: 655 IQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEV 476
E +L + E ++++ Q K+ ED+ T + + E +
Sbjct: 13663 EDEQILKRE-----------------REEIADMKDQLL--KEKEDVETTKERINREKEHI 13703
Query: 475 IKLQSQVENL--------QSLVQMLKQQNTKLELLAKKTSEMDPEK 362
K+QSQ+ + Q L+ M + K L K ++ E+
Sbjct: 13704 EKMQSQLNDQKEEMDLENQKLLYMKTEIQVKTNALEKMMQDLQKER 13749
Score = 63.5 bits (153), Expect = 4e-07
Identities = 110/654 (16%), Positives = 277/654 (42%), Gaps = 44/654 (6%)
Frame = -2
Query: 2230 RLDIQKEKNISEDL-------KETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSE 2072
+ DI+ K I + L K ++ + +LDIE++ D Q + +EL+ +
Sbjct: 11072 KCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERI 11131
Query: 2071 QMSLKRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKEL-NQA 1904
+ + +K+ +TL E E+ E K E++ E LK++L + K+L NQ
Sbjct: 11132 RNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRLKEDLEKMSTDVNKQNKDLMNQR 11191
Query: 1903 N----EEVKVLSKFRYQVLELEEYSQQLS----ADLSKVHEDYSAALRQLFDKKNEITCL 1748
+ E ++ K++ ++E+ Q+S DL K + + L + K + +
Sbjct: 11192 DLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPK-EKGMKEDRKSLEETKANVIEM 11250
Query: 1747 QEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFS 1568
+ E +E+++ + + E +I V ++ Y+ +++++ ++ +D
Sbjct: 11251 KTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELYQ-----IKSELERVRSEID-- 11303
Query: 1567 AGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQL 1388
E K+++ ++++ + L +++ E Q+ E + ++ K +
Sbjct: 11304 -----HEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDI 11358
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKS 1208
E S + + E + Q + D + + + L+NE +
Sbjct: 11359 EKSKEIVEKLMVEVE----EQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERI 11414
Query: 1207 KQM-EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEM 1031
K++ EE K + L + E + + + D+ K D+ L+ +
Sbjct: 11415 KKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQR 11474
Query: 1030 SSLKIELVEKNGFMGYAVLDVE------NVQKELL----IWKDRAMIAEGQSKAFQLELK 881
L+ E E N M ++ + Q+E L + ++R + E +++ +++ K
Sbjct: 11475 DLLEQEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTK 11534
Query: 880 HANMSICSLSEKIQQIEEREKVLL----TQLSTKDTDMQHLAAQLTLAQEEISSTKEMLK 713
I + EK ++ EE +V++ +L+ ++++ + +++ Q++++ K++++
Sbjct: 11535 AELQEI--MQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIE 11592
Query: 712 DFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFD-QSMDEAVSEIAVQTFPN 536
+++E + + + Q++E ++ ++ T D ++ E V ++ V+
Sbjct: 11593 QEKEDLEKMKSEIMTQRQQMEEE--RSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQ 11650
Query: 535 K-----DTEDINTEIAHTSDKDEEVI----KLQSQVENLQSLVQMLKQQNTKLE 401
+ E+++ E +D+ V+ KLQ++ E ++ + + +K++ L+
Sbjct: 11651 RKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLK 11704
>ref|XP_637450.1| zipper-like domain-containing protein [Dictyostelium discoideum AX4]
gi|60465873|gb|EAL63944.1| zipper-like domain-containing
protein [Dictyostelium discoideum AX4]
Length = 1024
Score = 103 bits (258), Expect = 2e-19
Identities = 139/694 (20%), Positives = 302/694 (43%), Gaps = 71/694 (10%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQ-----SEIYSLSAELERI--- 2084
D+ + +I ++NI L E +K L+ +++ + +T ++ S I + +L++
Sbjct: 238 DSHKKEITNKENIETTLLEKIKRLEQQIELNKSTTTQQKTPESNSPINQSTNDLQQYNYT 297
Query: 2083 ------TQSEQMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLE 1922
T + K + E + L +E+E + + ++ I +L+Q++SS +++ L
Sbjct: 298 LNGGNNTTTTTNLKKEITELQSELSNISAEKEIMVQKYQQQIVILQQQVSSFTEKVDDLT 357
Query: 1921 KELNQANEEVKVLSKF-------RYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKN 1763
L+Q ++ L++ +++ E ++ +A+L + E Y + + D+K+
Sbjct: 358 NVLSQKETKIGELTRATNGFTTKETELIRSYEDEKKRTAELLERLEMYEKMNKNITDEKD 417
Query: 1762 -EITCLQEVIEQKEVEER-----------QRECMLAASERSNDINVNALEKKLSAYEGKI 1619
+I L + +E K+ E++ Q + LA+++ + + + +LS + +
Sbjct: 418 FQIEKLVDQLEAKQSEQQTTTNNLQNEISQLKQQLASNQSTESQALQSKITELSQLQSEF 477
Query: 1618 RRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNV 1439
+L+N QL K++S + + Q + L+ + + + T+Q+ +
Sbjct: 478 EKLQN---QLQSKDSELLETSKKQSALLEQQSEDSQSKDEKLKSVELNLQQTLQQLQSKD 534
Query: 1438 EEFSSVVKHLEYLKSQLETSNTMDHD------TLSSTHQGSMEDKASSQSSTGDNDPKAX 1277
+E +V LE Q E S + D TL T Q + K+ + + N+ K
Sbjct: 535 QELQNVKSQLE---QQSEDSESKDQKLKSVELTLQQTLQQLQDVKSQLEQQSEHNESK-- 589
Query: 1276 XXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYL 1097
+E+ KS ++ LQ +L + S ++++ + CL
Sbjct: 590 -----------------DEKLKSIELN----LQQQLQSKDSELSSKDEQLKCL------- 621
Query: 1096 EGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFM-------GYAVLDVENVQKELLIW 938
E ++ KE L +E+SS+K +L+ K+ + +++++ +L
Sbjct: 622 ESELSSVKEQLSSQSSNTDSELSSVKDQLLSKDSELKSKDEQLSNKDSQIKSIESDLQSV 681
Query: 937 KDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQL 758
KD+ + + ++ + +L + + + +I+ IE + + QLS+KD ++Q QL
Sbjct: 682 KDQLSSKDQELQSTKDQLSSKDEQLSNKDTQIKSIESDLQSVKDQLSSKDQELQSTKDQL 741
Query: 757 TLAQEEISSTKEML----------KDFI-------DNMEASDTNLQSHFNQI----QEML 641
+ +E+ STK+ L KD + D + A DT LQS +Q+ E+
Sbjct: 742 SSKDQELQSTKDQLSTKDQELQSAKDQLSCQSSTTDQLSAKDTELQSTKDQLSSKDSELQ 801
Query: 640 LNQNVNYPLEATVNIGFDQ--SMDEAVSEIAVQ-TFPNKDTEDINTEI-AHTSDKDEEVI 473
++ ++ + DQ S D + I Q + + D + + ++ + SD
Sbjct: 802 SIKDQLSTKDSELQSSKDQLSSKDSELQSIKDQLSSKDSDLQSVKDQLSSKDSDLQSTKD 861
Query: 472 KLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMD 371
+L S+ + LQS+ L ++ +L+ + K SE D
Sbjct: 862 QLSSKDQELQSVKDELTSKDQELQQITSKQSEQD 895
>gb|AAB70839.1| ZipA [Dictyostelium discoideum]
Length = 924
Score = 103 bits (258), Expect = 2e-19
Identities = 139/694 (20%), Positives = 302/694 (43%), Gaps = 71/694 (10%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQ-----SEIYSLSAELERI--- 2084
D+ + +I ++NI L E +K L+ +++ + +T ++ S I + +L++
Sbjct: 238 DSHKKEITNKENIETTLLEKIKRLEQQIELNKSTTTQQKTPESNSPINQSTNDLQQYNYT 297
Query: 2083 ------TQSEQMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLE 1922
T + K + E + L +E+E + + ++ I +L+Q++SS +++ L
Sbjct: 298 LNGGNNTTTTTNLKKEITELQSELSNISAEKEIMVQKYQQQIVILQQQVSSFTEKVDDLT 357
Query: 1921 KELNQANEEVKVLSKF-------RYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKN 1763
L+Q ++ L++ +++ E ++ +A+L + E Y + + D+K+
Sbjct: 358 NVLSQKETKIGELTRATNGFTTKETELIRSYEDEKKRTAELLERLEMYEKMNKNITDEKD 417
Query: 1762 -EITCLQEVIEQKEVEER-----------QRECMLAASERSNDINVNALEKKLSAYEGKI 1619
+I L + +E K+ E++ Q + LA+++ + + + +LS + +
Sbjct: 418 FQIEKLVDQLEAKQSEQQTTTNNLQNEISQLKQQLASNQSTESQALQSKITELSQLQSEF 477
Query: 1618 RRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNV 1439
+L+N QL K++S + + Q + L+ + + + T+Q+ +
Sbjct: 478 EKLQN---QLQSKDSELLETSKKQSALLEQQSEDSQSKDEKLKSVELNLQQTLQQLQSKD 534
Query: 1438 EEFSSVVKHLEYLKSQLETSNTMDHD------TLSSTHQGSMEDKASSQSSTGDNDPKAX 1277
+E +V LE Q E S + D TL T Q + K+ + + N+ K
Sbjct: 535 QELQNVKSQLE---QQSEDSESKDQKLKSVELTLQQTLQQLQDVKSQLEQQSEHNESK-- 589
Query: 1276 XXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYL 1097
+E+ KS ++ LQ +L + S ++++ + CL
Sbjct: 590 -----------------DEKLKSIELN----LQQQLQSKDSELSSKDEQLKCL------- 621
Query: 1096 EGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFM-------GYAVLDVENVQKELLIW 938
E ++ KE L +E+SS+K +L+ K+ + +++++ +L
Sbjct: 622 ESELSSVKEQLSSQSSNTDSELSSVKDQLLSKDSELKSKDEQLSNKDSQIKSIESDLQSV 681
Query: 937 KDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQL 758
KD+ + + ++ + +L + + + +I+ IE + + QLS+KD ++Q QL
Sbjct: 682 KDQLSSKDQELQSTKDQLSSKDEQLSNKDTQIKSIESDLQSVKDQLSSKDQELQSTKDQL 741
Query: 757 TLAQEEISSTKEML----------KDFI-------DNMEASDTNLQSHFNQI----QEML 641
+ +E+ STK+ L KD + D + A DT LQS +Q+ E+
Sbjct: 742 SSKDQELQSTKDQLSTKDQELQSAKDQLSCQSSTTDQLSAKDTELQSTKDQLSSKDSELQ 801
Query: 640 LNQNVNYPLEATVNIGFDQ--SMDEAVSEIAVQ-TFPNKDTEDINTEI-AHTSDKDEEVI 473
++ ++ + DQ S D + I Q + + D + + ++ + SD
Sbjct: 802 SIKDQLSTKDSELQSSKDQLSSKDSELQSIKDQLSSKDSDLQSVKDQLSSKDSDLQSTKD 861
Query: 472 KLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMD 371
+L S+ + LQS+ L ++ +L+ + K SE D
Sbjct: 862 QLSSKDQELQSVKDELTSKDQELQQITSKQSEQD 895
>ref|XP_001579764.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121913974|gb|EAY18778.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 3369
Score = 103 bits (257), Expect = 3e-19
Identities = 157/752 (20%), Positives = 325/752 (43%), Gaps = 44/752 (5%)
Frame = -2
Query: 2215 KEKNISEDLKETV---------KNLQSDLDIEQ--KLSTDRQSEIYSLSAELERITQSEQ 2069
K+K+I E++ E V KN Q D EQ ++T+ ++ I +L+ +L
Sbjct: 8 KDKSI-EEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNKNNEID 66
Query: 2068 MSLKRLKEAE---QTLLEAESERESLKAELEESISVLKQE----LSSARLQIESLEKELN 1910
+ ++L+ E L E SERE EL+E + KQE +S +L++ES + E+N
Sbjct: 67 LLHQQLQSKETEISKLTENVSEREKSFTELQEQLEKAKQEHEETISEIKLKLESKDNEIN 126
Query: 1909 QANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQ 1730
+ N LS+ R ++ + + + +L+ LS+ + + L + EI+ ++ I +
Sbjct: 127 ELN---STLSQIRSELEQTNKQNTELTETLSQKESNINEINDNLSKLREEISEKEKTINE 183
Query: 1729 K--EVEERQRECMLAASERSNDI-----NVNALEKKLSAYEGKIRRLENDVSQLTLSVDF 1571
K ++EE ++ SE+ N + +N LE++ +I L+ + L +
Sbjct: 184 KSSKIEELNQQ----ISEKDNSLKEMTEKINNLEEENKQKNSRIEELQQQLESLRNDDEN 239
Query: 1570 SAGVFKEESTKVSNACDLLQEI--------ENFLREIRVETK---VTIQEARHNVEEFSS 1424
EE ++ + + L E+ E L ++ + K I E NV + S
Sbjct: 240 RINNLYEELSQKESKINELNELMMQQQTGKETILSQLNEQIKEKDSKIGELEENVSKLES 299
Query: 1423 VV----KHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGD---NDPKAXXXXX 1265
+ ++ L SQ+ + M +D S + ++ + S Q+S D K
Sbjct: 300 EISQKESNINELSSQVSEKDKMVNDI--SEEKNELQKQLSDQNSMIDELNEQIKELTDNL 357
Query: 1264 XXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDI 1085
++ +N+E S++ E L+ E++ L+ + E K + + +
Sbjct: 358 SKSTTESTEKDSKNQELISEKETEISHLKEEISK-LTEQHGEKDKLIQELTEQIQTQDIN 416
Query: 1084 LKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQS 905
LK K+ N +L+ +S + EL EK+ + + +E +K+L I + + +S
Sbjct: 417 LKQKDS---NISELQVLVSQKETELSEKDNSINEFIHKLE--EKDLQIKELNEQLNNKES 471
Query: 904 KAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTK 725
++ N I +Q+I ++ L + K+T++ +L+ + +I+
Sbjct: 472 -----QINELNAQISDKENSLQEITDKVHTLEETVQNKETEINQKNEELSERETKINELN 526
Query: 724 EMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEI-AVQ 548
E++ ++ + + S+ ++I E LNQ ++ + S+ E ++ +++
Sbjct: 527 EIISQKDSEIQQKNEEISSNNSKIDE--LNQQIS---------NKENSLQELTDKVHSLE 575
Query: 547 TFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDP 368
T ++ I+ S+K+EE KLQ E +Q+ +K + +K++ + ++ S+ D
Sbjct: 576 TKNSEQETQIDELTKLVSEKEEENNKLQ---ETIQTKETEIKDKQSKVDEMNQEISDKDK 632
Query: 367 EKYFHFEELCQSLVXXXXXXXXXXXXXXXKNQVLVKQVKEMQVTLQSESPMEGETDSISE 188
EE+ + + +N+ Q+ EM+ + S + E E
Sbjct: 633 S----IEEITERV-----------NKLEEENKTKNSQIDEMKEQISSITTNE-------E 670
Query: 187 NAIGSQPAGKLSTELHNVHGNTERVPLQLLNK 92
AI + L+T+L+N + + + QL +K
Sbjct: 671 TAIST-----LNTQLNNKNNEIDLLHQQLQSK 697
Score = 100 bits (250), Expect = 2e-18
Identities = 138/662 (20%), Positives = 285/662 (43%), Gaps = 44/662 (6%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQS---EQMSLKR 2054
DI +K + KE++ N + KL+T+R+S+I LS +L ++ + E +S +
Sbjct: 1268 DIISKKEEEKAEKESLLNENIN-----KLNTERESQINELSEKLLKLEEQLKQETLSNED 1322
Query: 2053 LKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKF 1874
+K+ +L + E ++ + L Q+++ QI +K +N EE+K S
Sbjct: 1323 MKQTNTSLSQKIDEMAFQLSDKTSQLQELNQQITVLSSQISDKDKTVNDLQEEIKEKSVQ 1382
Query: 1873 RYQ----VLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQR 1706
+ + +L+E+ +Q D+ E + ++ K NEI + +E KE E Q
Sbjct: 1383 NEENSRIINDLKEFIKQYDEDIKSKDEKIKSIEQEKDAKINEI---KAELETKETENSQL 1439
Query: 1705 ECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVD-FSAGVFKEESTKVSN 1529
N++ L+ LS+ + + + +D ++L ++ + + ++E+ S
Sbjct: 1440 FG-----------NISELQNMLSSRDSEYETVCSDNNKLKQEIEALKSSLSEKENDFASI 1488
Query: 1528 ACDLLQEIENFLREIRVETKV---TIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDT 1358
+E+ N +E+ TK Q+ E S++ K +E LKS L
Sbjct: 1489 LSKYDEEVSNHNKEVEELTKKDEENKQQVDEKENEISNLKKEIENLKSSLNE-------- 1540
Query: 1357 LSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQ 1178
+D SQ+S +D + +Q E K +++ K +
Sbjct: 1541 ---------KDNEISQNSQAIDDSSKHVQELQHQFDEDLKQKQEEISAKDEELSNLKKVL 1591
Query: 1177 AELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLN-HGQLRAE---MSSLKIEL 1010
E + ++ E + + + +++ KE ++ + G++ E +++ + E+
Sbjct: 1592 EEEKSEITSSLQEKDELIKQKEEEISNLNSVIQEKEKVIASLQGKVNDENNEVNAKEAEI 1651
Query: 1009 VEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIE 830
V N ++ ++Q++L + IAE + + +L+ SI ++I ++
Sbjct: 1652 VSLNEIQKKKEEEISSLQEKL-----NSTIAEKEKEISELQ-----SSINDKDKEISSLQ 1701
Query: 829 EREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQ-- 656
E+ + ++TK+T++ L QL EEI++ K +K+ + + + LQS N+
Sbjct: 1702 EKVNIENNDVNTKETEISSLNDQLKQKDEEINNLKSEIKEKFEEL----SKLQSLVNENE 1757
Query: 655 -----IQEMLLNQNVNYPLEATVN----IGFDQSMDEAVSEIAV--QTFPN----KDTED 521
+QE + + +N E + + S+ E EI++ + F N KD E
Sbjct: 1758 QVIVSLQEKVNSDEINKENELKMKEEEISNLNGSIQEKEKEISLLKENFNNSLAQKDEEI 1817
Query: 520 IN-------TEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQ-----NTKLELLAKKTSE 377
N + TS E++ KLQS+++ + + +++ N KLELL +K E
Sbjct: 1818 SNLKKVLEEEKSGITSSLQEQISKLQSEIKERDEIQKKKEEEIQTLSNEKLELLKQKEEE 1877
Query: 376 MD 371
++
Sbjct: 1878 IN 1879
Score = 95.9 bits (237), Expect = 7e-17
Identities = 145/698 (20%), Positives = 295/698 (42%), Gaps = 97/698 (13%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
++AV+ ++ K+ +++ +E + S+ D E S + S + AE E+ S+ +
Sbjct: 859 IEAVQSELAKKDKENKEFEELMSQAISEKDEEISKSKNGISSLQEKLAEKEKEINSKNEA 918
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVK-- 1889
KE L+ S+R+ + L +SI L++E+S+ I E ++N+ EE+
Sbjct: 919 NTAEKEENSKLI---SQRDEEISNLNKSIDELRKEISTKDETISQFESKINELIEEISKK 975
Query: 1888 --VLSKFRYQVLELEEYSQQLSADLSKVHE-------DYSAALRQLFDKKNEITCLQEVI 1736
+++ ++ EL E Q +++ + E S QL +K+ I L+E +
Sbjct: 976 ELTINEKETKIAELNEQITQKENEINGLKEAEKVMETKISEIESQLTEKEKSINELEETV 1035
Query: 1735 EQKEVEERQRECMLAASE-RSNDIN----------------VNALEKKLSAYEGKIRRLE 1607
+ KE E Q+ L+ E + N++N +++ K+ +I E
Sbjct: 1036 QNKETEINQKNEELSERETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQISNKE 1095
Query: 1606 NDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIE---NFLREIRVETKVT-IQEARHNV 1439
N + +LT V E+ T++ L+ E E N L+E ++TK T I++ + V
Sbjct: 1096 NSLQELTDKVHSLETKNSEQETQIEELTKLVSEKEEENNKLQET-IQTKETEIKDKQSKV 1154
Query: 1438 EEFSSVVKHLEYLKSQL-ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXX 1262
+E + + + ++ E N ++ + + T +++ SS N+ A
Sbjct: 1155 DEMNQEISDKDKSIEEITERVNKLEEE--NKTKNSQIDEMKEQISSITTNEETAISTLNT 1212
Query: 1261 XXXXXECRQNLENEECKSKQMEEYKMLQ--AELNNWLSCMNAEMGKFLCLCNSMVYLEGD 1088
+L +++ +SK+ E ++ + +E NN L E+ + N + D
Sbjct: 1213 QLNNKNNEIDLLHQQLQSKETEIKQLNEEISERNNALQTKETEIKEKELKINEL----ND 1268
Query: 1087 ILKYKED--------LLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKD 932
I+ KE+ L N +L E S EL EK + L E + E + +
Sbjct: 1269 IISKKEEEKAEKESLLNENINKLNTERESQINELSEKLLKLEEQ-LKQETLSNEDMKQTN 1327
Query: 931 RAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKD---TDMQHLAAQ 761
++ + AFQL K + ++Q++ ++ VL +Q+S KD D+Q +
Sbjct: 1328 TSLSQKIDEMAFQLSDK---------TSQLQELNQQITVLSSQISDKDKTVNDLQEEIKE 1378
Query: 760 LTLAQEE----ISSTKEMLKDFIDNMEASDTNLQS------------------------- 668
++ EE I+ KE +K + +++++ D ++S
Sbjct: 1379 KSVQNEENSRIINDLKEFIKQYDEDIKSKDEKIKSIEQEKDAKINEIKAELETKETENSQ 1438
Query: 667 ---HFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQ-----TFPNKDTEDI-- 518
+ +++Q ML +++ Y + N Q ++ S ++ + + +K E++
Sbjct: 1439 LFGNISELQNMLSSRDSEYETVCSDNNKLKQEIEALKSSLSEKENDFASILSKYDEEVSN 1498
Query: 517 -NTEIAHTSDKDEE-----------VIKLQSQVENLQS 440
N E+ + KDEE + L+ ++ENL+S
Sbjct: 1499 HNKEVEELTKKDEENKQQVDEKENEISNLKKEIENLKS 1536
Score = 92.8 bits (229), Expect = 6e-16
Identities = 129/684 (18%), Positives = 299/684 (43%), Gaps = 54/684 (7%)
Frame = -2
Query: 2215 KEKNIS-EDLKETVKNLQSDLDIEQKLST------DRQSEIYSLSAELERITQSEQMSLK 2057
K KN +++KE + ++ ++ E +ST ++ +EI L +L+ + ++
Sbjct: 649 KTKNSQIDEMKEQISSITTNE--ETAISTLNTQLNNKNNEIDLLHQQLQSKETENEKAIN 706
Query: 2056 RLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVK---- 1889
L + L E + + + EL E IS QE+ +++SL ELNQ NEE+K
Sbjct: 707 ELNDKLNKLYEEIANKNTNITELNEQISSKNQEIVDRDNKLQSLGTELNQKNEEIKEKDS 766
Query: 1888 -------VLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQ 1730
++SK ++ +L+E +S+ + +++ + + + + N+I ++ ++
Sbjct: 767 KIGEFNDLVSKKDSEINQLQEEIADISSKIEELNNEIATKDASILELNNKIA--EKDLKI 824
Query: 1729 KEVEERQRECMLAASERSNDIN------------VNALEKKLSAYEGKIRRLENDVSQLT 1586
K ++E + +E+ NDI+ + A++ +L+ + + + E +SQ
Sbjct: 825 KSLDEEKSSLQSKPAEKENDISDLLVKYDEKCSEIEAVQSELAKKDKENKEFEELMSQAI 884
Query: 1585 LSVDFSAGVFKEESTKVSNACDLLQE-IENFLREIRVETKVTIQEARHNV-------EEF 1430
D EE +K N LQE + +EI + + E N EE
Sbjct: 885 SEKD-------EEISKSKNGISSLQEKLAEKEKEINSKNEANTAEKEENSKLISQRDEEI 937
Query: 1429 SSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXX 1250
S++ K ++ L+ ++ T + S ++ +E+ + + + + + K
Sbjct: 938 SNLNKSIDELRKEISTKDETISQFESKINE-LIEEISKKELTINEKETKIAELNEQI--- 993
Query: 1249 XECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKE 1070
ENE K+ E K+++ +++ S + + L ++ E +I + E
Sbjct: 994 ----TQKENEINGLKEAE--KVMETKISEIESQLTEKEKSINELEETVQNKETEINQKNE 1047
Query: 1069 DLLLNH---GQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKA 899
+L +L +S E+ +KN + ++ + ++ I + E K
Sbjct: 1048 ELSERETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQ--ISNKENSLQELTDKV 1105
Query: 898 FQLELKHANM--SICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTK 725
LE K++ I L++ + + EE L + TK+T+++ +++ +EIS
Sbjct: 1106 HSLETKNSEQETQIEELTKLVSEKEEENNKLQETIQTKETEIKDKQSKVDEMNQEISDKD 1165
Query: 724 EMLKDF---IDNMEASDTNLQSHFNQIQEMLLNQNVNYPLE-ATVNIGFDQSMDEAVSEI 557
+ +++ ++ +E + S ++++E + + N +T+N + +E ++
Sbjct: 1166 KSIEEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNKNNEI--DL 1223
Query: 556 AVQTFPNKDTE--DINTEIAHTSD----KDEEVIKLQSQVENLQSLVQMLKQQNTKLE-L 398
Q +K+TE +N EI+ ++ K+ E+ + + ++ L ++ +++ + E L
Sbjct: 1224 LHQQLQSKETEIKQLNEEISERNNALQTKETEIKEKELKINELNDIISKKEEEKAEKESL 1283
Query: 397 LAKKTSEMDPEKYFHFEELCQSLV 326
L + ++++ E+ EL + L+
Sbjct: 1284 LNENINKLNTERESQINELSEKLL 1307
Score = 88.6 bits (218), Expect = 1e-14
Identities = 113/568 (19%), Positives = 248/568 (43%), Gaps = 35/568 (6%)
Frame = -2
Query: 1969 LKQELSSARLQIESLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAA 1790
+ QE+S IE + + +N+ EE K + +++E +Q+S+ + S
Sbjct: 1 MNQEISDKDKSIEEITERVNKLEEENKTKNS------QIDEMKEQISSITTNEETAISTL 54
Query: 1789 LRQLFDKKNEITCLQEVIEQKEVE---------ERQR-----ECMLAASERSNDINVNAL 1652
QL +K NEI L + ++ KE E ER++ + L +++ ++ ++ +
Sbjct: 55 NTQLNNKNNEIDLLHQQLQSKETEISKLTENVSEREKSFTELQEQLEKAKQEHEETISEI 114
Query: 1651 EKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIR--- 1481
+ KL + + +I L + +SQ+ ++ + E + +S + EI + L ++R
Sbjct: 115 KLKLESKDNEINELNSTLSQIRSELEQTNKQNTELTETLSQKESNINEINDNLSKLREEI 174
Query: 1480 VETKVTIQEARHNVEEFSSVVKHLE-YLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSS 1304
E + TI E +EE + + + LK E N ++ + + + S ++ Q
Sbjct: 175 SEKEKTINEKSSKIEELNQQISEKDNSLKEMTEKINNLEEE---NKQKNSRIEELQQQLE 231
Query: 1303 TGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQ--------AELNNWLSCM 1148
+ ND + + L +E K ++ E M Q ++LN +
Sbjct: 232 SLRNDDE--------NRINNLYEELSQKESKINELNELMMQQQTGKETILSQLNEQIKEK 283
Query: 1147 NAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDV 968
++++G+ LE ++ K + ++ Q + ++ L ++ EK+ + +
Sbjct: 284 DSKIGE----------LEENVSKLESEI----SQKESNINELSSQVSEKDKMVNDISEEK 329
Query: 967 ENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKD 788
+QK+L +MI E + +L +LS+ + E++ +S K+
Sbjct: 330 NELQKQLS--DQNSMIDELNEQIKEL--------TDNLSKSTTESTEKDSKNQELISEKE 379
Query: 787 TDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEM--LLNQNVNYPL 614
T++ HL +++ E+ +++++ + ++ D NL+ + I E+ L++Q
Sbjct: 380 TEISHLKEEISKLTEQHGEKDKLIQELTEQIQTQDINLKQKDSNISELQVLVSQKETELS 439
Query: 613 EATVNIG-FDQSMDEAVSEIAV--QTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQ 443
E +I F ++E +I + NK+++ IN A SDK+ + ++ +V L+
Sbjct: 440 EKDNSINEFIHKLEEKDLQIKELNEQLNNKESQ-INELNAQISDKENSLQEITDKVHTLE 498
Query: 442 SLVQ----MLKQQNTKLELLAKKTSEMD 371
VQ + Q+N +L K +E++
Sbjct: 499 ETVQNKETEINQKNEELSERETKINELN 526
Score = 87.4 bits (215), Expect = 2e-14
Identities = 137/686 (19%), Positives = 293/686 (42%), Gaps = 68/686 (9%)
Frame = -2
Query: 2218 QKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAE-LERITQSEQM-------- 2066
+++ I+ L+E + LQS++ ++ ++ EI +LS E LE + Q E+
Sbjct: 1826 EEKSGITSSLQEQISKLQSEIKERDEIQKKKEEEIQTLSNEKLELLKQKEEEINVLNSKL 1885
Query: 2065 --SLKRLKEAE------QTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELN 1910
S++ LK+ E + E ++E +EL+ I+ LK ELS+ + ++E L + +
Sbjct: 1886 NESVELLKQKEGDNENNDKISEIRQQKEKEISELQSEINSLKNELSANKEEMEKLNETIK 1945
Query: 1909 QANEEV------------------KVLSKFRYQVLELEEYSQQLSADLSKVHE--DYSAA 1790
+ +EE+ +LS + ++ + S + SK E D
Sbjct: 1946 ERDEEISSIKQKADDDKSEVNSISNILSDIKQKLSNQTQESIKEGRVFSKEREVPDEETN 2005
Query: 1789 LRQL-----FDKKNEITCLQEVIEQKEVEERQ-----RECMLAASERSNDINVN------ 1658
+ QL K +E+ +EVIE + +E R + SE +++ N
Sbjct: 2006 ISQLDYSPIKSKPSEVVKSREVIELVDEDEGNETNDIRSTVEYLSETIDEMQANIEELKK 2065
Query: 1657 -----ALEKKLSAYEGKIRRLENDVSQLTLSVDFSA--GVFKEESTKVSNACDLLQEIEN 1499
+ EK+ Y+ + R+ D +++ ++ + +++ + N LQ +
Sbjct: 2066 ENAKKSQEKQSLIYQNQQLRILLDSAEIEMNKKSQGMMTMMNDKNGLIENLTKELQTTRS 2125
Query: 1498 FLREIRVETKVTIQEAR----HNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSM 1331
L +I+ + +Q+ + ++ + ++ Q+ + D ++ T Q
Sbjct: 2126 QLNDIKQQAVYQMQQQKSFDDQEIQRLNGLISQKLSENEQMRQQFNLQADAMNKTIQ--E 2183
Query: 1330 EDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNL--ENEECKSKQMEEYKMLQAELNNWL 1157
+D+ +Q T +A QNL ENEE S++ E ++++LN +
Sbjct: 2184 KDEMINQIKT-----RANKLLNEKLNENSNLQNLQKENEEKLSQKENELNQIKSQLNTVI 2238
Query: 1156 SCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAV 977
NA+ + L N + +E +K +EDL+ N +L E S + L+E +
Sbjct: 2239 --QNAQ-SQISALQNEKIAIENK-MKQQEDLIQNM-KLANESSEQSLSLLEGENSKLEQI 2293
Query: 976 LDVENVQKELLIWKDRAMIAEGQSKAFQ--LELKHANMSICSLSEKIQQIEEREKVLLTQ 803
KE I K +AM E + K Q E+ N + +Q + L++
Sbjct: 2294 CANLKKSKEEEIEKMKAMFNEYKVKVMQDRTEILSQNEQLKQNYISLQNELASSRNNLSE 2353
Query: 802 LSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVN 623
+++ + + L + + + + +S ++ I+ ++ + NL+++ +Q+ E+ QN N
Sbjct: 2354 INSLQSKVNDLQNENSNIKSKANSMLSSMQQKINELQTENINLKNNQSQLNEL---QNSN 2410
Query: 622 YPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQ 443
L+ +N ++ + SEI+ + ++ NT I + + + + L +Q++ Q
Sbjct: 2411 NSLQTKLN-ELEKENETKNSEISSLQQKLNELQNDNTTIKNKA--NSILNSLNNQLKESQ 2467
Query: 442 SLVQMLKQQNTKLELLAKKTSEMDPE 365
+ + L+ +NT ++ L + + E
Sbjct: 2468 TKLNELQNENTSIKTLETQIHSLQTE 2493
Score = 86.3 bits (212), Expect = 5e-14
Identities = 132/676 (19%), Positives = 277/676 (40%), Gaps = 80/676 (11%)
Frame = -2
Query: 2197 EDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTLLEAE 2018
E+L + V + + + Q+ +++EI ++++ + Q K ++E + + + E
Sbjct: 1120 EELTKLVSEKEEENNKLQETIQTKETEIKDKQSKVDEMNQEISDKDKSIEEITERVNKLE 1179
Query: 2017 SERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQVLELEEYSQ 1838
E ++ ++++E + ++ I +L +LN N E+ +L + Q+ E +
Sbjct: 1180 EENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNKNNEIDLLHQ---QLQSKETEIK 1236
Query: 1837 QLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVN 1658
QL+ ++S+ + ++ +K+ +I L ++I +KE E+ ++E +L +E N +N
Sbjct: 1237 QLNEEISERNNALQTKETEIKEKELKINELNDIISKKEEEKAEKESLL--NENINKLNTE 1294
Query: 1657 ALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRV 1478
E +++ K+ +LE + Q TLS + S K+ L + + L+E+
Sbjct: 1295 R-ESQINELSEKLLKLEEQLKQETLSNEDMKQTNTSLSQKIDEMAFQLSDKTSQLQELNQ 1353
Query: 1477 ETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTG 1298
+ V + + + + + ++ Q E ++ + +D Q + K+ +
Sbjct: 1354 QITVLSSQISDKDKTVNDLQEEIKEKSVQNEENSRIINDLKEFIKQYDEDIKSKDEKIKS 1413
Query: 1297 DNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQ--AELNNWLSCMNAEMGKFL 1124
K + + N E ++K+ E ++ +EL N LS ++E + +
Sbjct: 1414 IEQEK------------DAKINEIKAELETKETENSQLFGNISELQNMLSSRDSEY-ETV 1460
Query: 1123 CLCNSMVYLEGDILK----------------YKEDLLLNHGQ------------------ 1046
C N+ + E + LK Y E++ NH +
Sbjct: 1461 CSDNNKLKQEIEALKSSLSEKENDFASILSKYDEEVS-NHNKEVEELTKKDEENKQQVDE 1519
Query: 1045 -------LRAEMSSLKIELVEKNGFMGYAVLDVENVQKEL----------LIWKDRAMIA 917
L+ E+ +LK L EK+ + +++ K + L K + A
Sbjct: 1520 KENEISNLKKEIENLKSSLNEKDNEISQNSQAIDDSSKHVQELQHQFDEDLKQKQEEISA 1579
Query: 916 EGQS-----KAFQLELKHANMSICSLSEKIQQ-----------IEEREKVLLT------- 806
+ + K + E S+ E I+Q I+E+EKV+ +
Sbjct: 1580 KDEELSNLKKVLEEEKSEITSSLQEKDELIKQKEEEISNLNSVIQEKEKVIASLQGKVND 1639
Query: 805 ---QLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLN 635
+++ K+ ++ L +EEISS +E L I E + LQS N + + +
Sbjct: 1640 ENNEVNAKEAEIVSLNEIQKKKEEEISSLQEKLNSTIAEKEKEISELQSSINDKDKEISS 1699
Query: 634 QNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQV 455
L+ VNI + + ++ + E+IN + +K EE+ KLQS V
Sbjct: 1700 ------LQEKVNIENNDVNTKETEISSLNDQLKQKDEEINNLKSEIKEKFEELSKLQSLV 1753
Query: 454 -ENLQSLVQMLKQQNT 410
EN Q +V + ++ N+
Sbjct: 1754 NENEQVIVSLQEKVNS 1769
Score = 82.4 bits (202), Expect = 8e-13
Identities = 134/645 (20%), Positives = 276/645 (42%), Gaps = 44/645 (6%)
Frame = -2
Query: 2203 ISEDLKETVK-----NLQSDLDIEQKLSTDRQ-SEIYSLSAELERITQSEQMSLKRL-KE 2045
IS+ L E + NLQ+D + D ++I + + +L +E +L+ L KE
Sbjct: 2156 ISQKLSENEQMRQQFNLQADAMNKTIQEKDEMINQIKTRANKLLNEKLNENSNLQNLQKE 2215
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSA---RLQIESLEKELNQANEEVKVLSKF 1874
E+ L + E+E +K++L I + ++S+ ++ IE+ K+ + +K+ ++
Sbjct: 2216 NEEKLSQKENELNQIKSQLNTVIQNAQSQISALQNEKIAIENKMKQQEDLIQNMKLANES 2275
Query: 1873 RYQVLELEEYS----QQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQR 1706
Q L L E +Q+ A+L K E+ ++ +F++ ++ +Q+ E E+ +
Sbjct: 2276 SEQSLSLLEGENSKLEQICANLKKSKEEEIEKMKAMFNEY-KVKVMQDRTEILSQNEQLK 2334
Query: 1705 ECMLA-----ASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEEST 1541
+ ++ AS R+N +N+L+ K++ + + +++ + + S+ + E+
Sbjct: 2335 QNYISLQNELASSRNNLSEINSLQSKVNDLQNENSNIKSKANSMLSSMQQKINELQTENI 2394
Query: 1540 KVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHD 1361
+ N L E++N ++ + +E E SS+ + L L++ T +
Sbjct: 2395 NLKNNQSQLNELQNSNNSLQTKLNELEKENETKNSEISSLQQKLNELQNDNTTIKNKANS 2454
Query: 1360 TLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSK-------- 1205
L+S + E + +N ENE KS+
Sbjct: 2455 ILNSLNNQLKESQTKLNELQNENTSIKTLETQIHSL------QTENETIKSQSQETINSL 2508
Query: 1204 ---------QMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSM------VYLEG-DILKYK 1073
Q++E LQ+ELN+ + + K L NS + +E +IL K
Sbjct: 2509 NSRISELQNQIQEISQLQSELNDLKTENQSLHEKISELTNSYNSKISELQIENQEILSSK 2568
Query: 1072 EDLLLNH-GQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAF 896
E + + +L+ E SLK+++ EK + N EL+ D ++ E K
Sbjct: 2569 EQISQSKLSELQNENQSLKLQISEKEEENEKLM----NSNSELMNQID--LVKEDTKK-- 2620
Query: 895 QLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEML 716
E+ H +I KI + +Q+S + + L +E S E+L
Sbjct: 2621 --EISHLQATINEKQTKIDGLN-------SQISQNEEERIGKLESLQSTIDEDKSQIEIL 2671
Query: 715 KDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPN 536
+ + ++E+ NLQ H+++I E +Q N+ +A V +++ +S++ +
Sbjct: 2672 EQKVSDLESKLENLQKHYSEI-ETKNSQYENFISKARVAFNENKA---KISQLETENNSL 2727
Query: 535 KDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLE 401
K+ + +N E A +S+ + L++ + +K++N+KLE
Sbjct: 2728 KE-KVVNYENAISSNDSQ-----------LKNFISQMKEENSKLE 2760
Score = 77.8 bits (190), Expect = 2e-11
Identities = 128/668 (19%), Positives = 292/668 (43%), Gaps = 30/668 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L++++ I ++K+ E L++ V +L+S L+ QK SEI + +++ E +++
Sbjct: 2654 LESLQSTIDEDKSQIEILEQKVSDLESKLENLQK----HYSEIETKNSQYENFISKARVA 2709
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVL 1883
E + + + E+E SLK ++ + + S + I +++E ++ EE L
Sbjct: 2710 FN---ENKAKISQLETENNSLKEKVVNYENAISSNDSQLKNFISQMKEENSKLEEEKSQL 2766
Query: 1882 SKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRE 1703
K ++ +LEE ++Q + LSK +E + R+ ++K ++ + E+ +EE ++
Sbjct: 2767 IKENQRIPQLEEENKQFANQLSKFNEKLTQIDRETEEEKTKL-----LTEKSNLEEEIKQ 2821
Query: 1702 CMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNAC 1523
+ +E N+ V LE++ S + K+ N + + ++ ++S K
Sbjct: 2822 -LKQQNEEINNEKVQ-LEEQFSNAKSKLAEEINQIKKPNEEIN------NDQSNKEEEKS 2873
Query: 1522 DLLQEIENFLREIRVETKVTIQEARHNV-EEFSSVVKHLEYLKSQLETSNTMDHDTLSST 1346
L ++I FL E + +QE H + E S + + L +K Q E N + L++
Sbjct: 2874 KLREQINEFLNE-----RTHLQEQIHQISNEKSQLQEELNEVKKQNEKINE-EIQLLNND 2927
Query: 1345 HQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKS---KQMEEYKMLQA 1175
EDK++ + + + EE KS KQ+ + + +
Sbjct: 2928 KSQLQEDKSALEEVLKQMEQQ--------------NDQSSTEEMKSNYEKQINDLQSKVS 2973
Query: 1174 ELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNG 995
EL N L E + L + + L + +E+ L Q++ ++ + ++
Sbjct: 2974 ELENKLISQTEEKSQIANLESVIEKLRNENKNIEEEKLKFEKQVKDLQTNAETNDQREDK 3033
Query: 994 FMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKI-QQIEEREK 818
+ + E +Q+++ +++ + I Q ++K I + +K +QI +
Sbjct: 3034 ITELKLRNAE-LQQQMKDYQNNSQI-----NLLQNQIKDLQSQISAQKQKYEEQINSQ-- 3085
Query: 817 VLLTQLSTKDTDMQHLAAQLTLAQ------EEISSTKEMLKDFIDNMEASDTNLQSHFNQ 656
T+ +D ++ + + L + +++ E LK I ++E T L S+ N
Sbjct: 3086 ---TKNEEEDEGIEVVNRDINLDEGEKDDFQKLKEENEQLKKKISDLE---TKLNSYVN- 3138
Query: 655 IQEMLLNQNV---NYPLEATVNIGFDQSMDEAVSEIAVQTFPN------KDTEDINTEI- 506
+ +L Q + ++ +++ G D+ A I +Q K ED+ +I
Sbjct: 3139 -ENAILQQKIAELGGDIDVSIDYGSDKDAIIAKLRILLQRALRLDKKRVKTIEDLEEKIK 3197
Query: 505 ---------AHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEKYFH 353
++ + +E++ +L+ ++EN ++ ++ Q+N L+ + +K++ + +
Sbjct: 3198 SFGVSVHNSSYEAQLEEQIKELKQKIENNEASDDLI-QKNESLKKMVQKSNTLYGQLMEE 3256
Query: 352 FEELCQSL 329
++L ++L
Sbjct: 3257 NQQLIKTL 3264
Score = 77.4 bits (189), Expect = 2e-11
Identities = 130/657 (19%), Positives = 274/657 (41%), Gaps = 44/657 (6%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQS-EQM 2066
+++++ ++ K E L ET+K ++ ++ + D +SE+ S+S L I Q
Sbjct: 1923 INSLKNELSANKEEMEKLNETIKERDEEISSIKQKADDDKSEVNSISNILSDIKQKLSNQ 1982
Query: 2065 SLKRLKEAEQTLLEAE-SERESLKAELEES-ISVLKQELSSARLQIESL-EKELNQANEE 1895
+ + +KE E E + E+ ++L+ S I E+ +R IE + E E N+ N+
Sbjct: 1983 TQESIKEGRVFSKEREVPDEETNISQLDYSPIKSKPSEVVKSREVIELVDEDEGNETNDI 2042
Query: 1894 VKVLSKFRYQVLELEEYSQQLSADLSKVHED------YSAALRQLFD-------KKNEIT 1754
+ + E++ ++L + +K ++ + LR L D KK++
Sbjct: 2043 RSTVEYLSETIDEMQANIEELKKENAKKSQEKQSLIYQNQQLRILLDSAEIEMNKKSQGM 2102
Query: 1753 CLQEVIEQKEVEERQRECMLAASERSNDINVNA---LEKKLSAYEGKIRRLENDVSQLTL 1583
+ +E +E S+ NDI A ++++ S + +I+RL +SQ
Sbjct: 2103 MTMMNDKNGLIENLTKELQTTRSQ-LNDIKQQAVYQMQQQKSFDDQEIQRLNGLISQKLS 2161
Query: 1582 SVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQE-----------ARHNVE 1436
+ F ++ ++ +QE + + +I+ + E + N E
Sbjct: 2162 ENEQMRQQFNLQADAMNKT---IQEKDEMINQIKTRANKLLNEKLNENSNLQNLQKENEE 2218
Query: 1435 EFSSVVKHLEYLKSQLET--SNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXX 1262
+ S L +KSQL T N + + ++E+K Q N A
Sbjct: 2219 KLSQKENELNQIKSQLNTVIQNAQSQISALQNEKIAIENKMKQQEDLIQNMKLA------ 2272
Query: 1261 XXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCN----SMVYLE 1094
N +E+ S E L+ N E+ K + N ++
Sbjct: 2273 ---------NESSEQSLSLLEGENSKLEQICANLKKSKEEEIEKMKAMFNEYKVKVMQDR 2323
Query: 1093 GDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAE 914
+IL E L N+ L+ E++S + L E N V D++N + K +M++
Sbjct: 2324 TEILSQNEQLKQNYISLQNELASSRNNLSEINSLQS-KVNDLQNENSNIKS-KANSMLSS 2381
Query: 913 GQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLS-------TKDTDMQHLAAQLT 755
Q K +L+ ++ N+ + ++ +++ L T+L+ TK++++ L +L
Sbjct: 2382 MQQKINELQTENINLK--NNQSQLNELQNSNNSLQTKLNELEKENETKNSEISSLQQKLN 2439
Query: 754 LAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMD 575
Q + ++ K ++++ Q+ N++Q N+N + T I Q+ +
Sbjct: 2440 ELQNDNTTIKNKANSILNSLNNQLKESQTKLNELQ----NENTSIKTLET-QIHSLQTEN 2494
Query: 574 EAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKL 404
E + + +T +N+ I+ ++ +E+ +LQS++ +L++ Q L ++ ++L
Sbjct: 2495 ETIKSQSQETI-----NSLNSRISELQNQIQEISQLQSELNDLKTENQSLHEKISEL 2546
>ref|XP_005159743.1| PREDICTED: titin isoform X6 [Danio rerio]
Length = 15134
Score = 102 bits (253), Expect = 9e-19
Identities = 127/657 (19%), Positives = 292/657 (44%), Gaps = 30/657 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD + ++ K++ D+ ET+KN + LD +++ +++ E+ +++ +S
Sbjct: 5748 LDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDED 5807
Query: 2062 LKRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQANEEV 1892
LK +K +Q + E +++ E +K ELE + I +K+E + R +E + +EL + ++V
Sbjct: 5808 LKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDV 5867
Query: 1891 KVLS----KFRYQVLELEEYSQQLSADLSK-------VHEDYSAALRQLFDKKNEITCLQ 1745
L+ + + + E++ ++ ADL K + E+ S + +K++I +
Sbjct: 5868 AHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLRE 5927
Query: 1744 EVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSA 1565
+ +EQ + E +++ + + + A+ K + + KI L+ D L L +
Sbjct: 5928 DELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDRE--- 5984
Query: 1564 GVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQL 1388
F+ E ++ L+ + + +I++ET Q R VEE ++ ++ + + QL
Sbjct: 5985 -AFENEKEELKQMKTELEREADEIEKIKLET----QHERQRVEEMTADFMETMNNERKQL 6039
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKS 1208
+ + M E K + D D +Q LE E+ K
Sbjct: 6040 DKNKVMIE-----------EQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKL 6088
Query: 1207 KQM--------EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL---- 1064
+QM +E ++ E N + L YL +I + + L
Sbjct: 6089 EQMKIGLEREADEISKIKEETQNERQNLEKMAN---ALKEEREYLAEEIKRKNQVLDKIK 6145
Query: 1063 LLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKD--RAMIAEGQSKAFQL 890
+ N L A++ K L E + + D+EN +++ + +D + + E Q + ++
Sbjct: 6146 VANESTL-ADLQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEI 6204
Query: 889 ELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKD 710
+++ N+ SE+ I E++ ++T+L K D++ ++ +E + + + +LK
Sbjct: 6205 DMEKTNIE----SERAAMIREKQN-MMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKK 6259
Query: 709 FIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKD 530
+++++ +++ ++++ EA N ++M + +++ +Q +
Sbjct: 6260 DVEDLQQKLMSIERD---------SESLKLDKEAFEN--EKEAMKQMKTDLQIQA---DE 6305
Query: 529 TEDINTEIAHTSDK-DEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEK 362
E I E H + +E+ ++Q + E + +LV+ +K+ K +++ + +E+ EK
Sbjct: 6306 IEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIKK---KRDIIDESYTEIRKEK 6359
Score = 100 bits (250), Expect = 2e-18
Identities = 128/638 (20%), Positives = 274/638 (42%), Gaps = 31/638 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD + ++ K++ D+ ET+KN + LD +++ + +++ E+ + ++ +S
Sbjct: 4461 LDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 4520
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEE---SISVLKQELSSARLQIESLEKELNQANEEV 1892
LK +K +Q L + +S+ E +K ELE I +K+E+ + R +E + + L + E++
Sbjct: 4521 LKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL 4580
Query: 1891 KVLSKFRYQVL-ELEEYSQQLSAD-------LSKVHEDYSAALRQLFDKKNEITCLQEVI 1736
+K QVL E++ ++ AD L ++ E+ S + +KK + ++ +
Sbjct: 4581 AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDEL 4640
Query: 1735 EQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTL---SVDFSA 1565
Q + E +++ + + + + A+ K + + KI L+ D L L + +
Sbjct: 4641 RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEK 4700
Query: 1564 GVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQL 1388
V K+ T++ D +++I K+ Q R VEE ++ + K + + + +
Sbjct: 4701 EVLKQMKTELEREADEIEKI-----------KLETQHDRQRVEEMAAQIQKDRDEINNLI 4749
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE---- 1220
E +N D L+ ++ E S QS + + + +++LE +
Sbjct: 4750 EETNRKDM-VLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENT 4808
Query: 1219 --------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL 1064
E K E E+ + MN + + L + L+ ++ K KE +
Sbjct: 4809 LAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEII 4868
Query: 1063 LLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLEL 884
+ + QL S L + N M ++N +K+L KD+ + E Q + + E
Sbjct: 4869 MKDRSQLDLRQSELDKQQTNMNDIME----TMKNERKQL--DKDKEEMEE-QKQEMEKER 4921
Query: 883 KHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFI 704
+ + S SL E +++ K+ + ++ + +L +EIS KE ++
Sbjct: 4922 DNMDQSRKSLDED----QKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKR 4977
Query: 703 DNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAV----QTFPN 536
+E L + + + + + + + SM + E ++ + +
Sbjct: 4978 QRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENIS 5037
Query: 535 KDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
K E I+ E + +++E+ KLQ++V+ QS + M K
Sbjct: 5038 KLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEK 5075
Score = 95.1 bits (235), Expect = 1e-16
Identities = 127/646 (19%), Positives = 274/646 (42%), Gaps = 26/646 (4%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
D+Q+EK+I E+++E + L+ +D E++ S R+ E+ L E++ K+ +
Sbjct: 5021 DLQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQ----------KQQSK 5070
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSK---- 1877
+ ESER ++ E + ++ LK++ +Q++ + E + + K+L++
Sbjct: 5071 IDMEKTNIESERAAMIREKQNMMTELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVEN 5130
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVE---ERQR 1706
+ ++++LE S++L D + E+ A++Q+ K ++ + IE+ ++E +RQR
Sbjct: 5131 LQQKLIDLERDSKRLKLD-REAFENEKEAMKQM---KTDLQIQADEIEKIKLETQHDRQR 5186
Query: 1705 ECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNA 1526
+AA + +N L ++ + + + D+ + S+ + ++E +
Sbjct: 5187 VEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKT 5246
Query: 1525 CDLLQEIENFLREIRVETKVTIQEARHNVEEFS-SVVKHLEYLKSQLETSNTMDHDTLSS 1349
L +++ L + + T IQ+ R +VE+ + ++ + + +K Q E N
Sbjct: 5247 RSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMN--------- 5297
Query: 1348 THQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-ECKSKQMEEYKMLQAE 1172
+D+ + N +Q LE E E K ++ + Q+E
Sbjct: 5298 ----QKQDELDQLKTEIQN----------------LQQELEKEKEIIMKDRSQFDLRQSE 5337
Query: 1171 L-------NNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIE 1013
L N+ + M E + M + ++ K K D + L ++ +K++
Sbjct: 5338 LDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKDLKMMKLQ 5397
Query: 1012 ---LVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSE-- 848
E+ + +++E E+ K+ + ELK S L+E
Sbjct: 5398 KQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFTHLAEDT 5457
Query: 847 -KIQQIEEREKV----LLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASD 683
K Q+I ++ KV L+ L + ++++ + ++ E++ + KE L+ D +
Sbjct: 5458 KKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLREDEL---- 5513
Query: 682 TNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIA 503
LQ+ + Q + + +N E I K+ ED+ +I
Sbjct: 5514 WQLQAEIYKQQREIEKEKINIESERAAII--------------------KNVEDLQHKII 5553
Query: 502 HTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPE 365
+ D+D E +KL E ++ ++LKQ T+LE A + ++ E
Sbjct: 5554 -SLDRDSESLKLDR--EAFENEREVLKQMKTELEREADEIEKIKLE 5596
Score = 92.0 bits (227), Expect = 1e-15
Identities = 127/649 (19%), Positives = 278/649 (42%), Gaps = 43/649 (6%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSL 2060
D + ++ K++ D+ ET+KN + LD +++ +++ E+ + ++ +S L
Sbjct: 5332 DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKDL 5391
Query: 2059 KRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQANE--- 1898
K +K +Q E +++ E +K ELE + I +K+E + R +E + +EL + E
Sbjct: 5392 KMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFT 5451
Query: 1897 --------EVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQE 1742
E ++L K + L Q+ ++L ++ E+ S + +KK + ++
Sbjct: 5452 HLAEDTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLRED 5511
Query: 1741 VIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTL---SVDF 1571
+ Q + E +++ + + + + A+ K + + KI L+ D L L + +
Sbjct: 5512 ELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFEN 5571
Query: 1570 SAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKS 1394
V K+ T++ D +++I K+ Q R VEE ++ + K + + +
Sbjct: 5572 EREVLKQMKTELEREADEIEKI-----------KLETQHDRQRVEEMTAQIQKDRDKINN 5620
Query: 1393 QLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-- 1220
+E +N D L+ ++ + S QS + + + +++LE +
Sbjct: 5621 LIEETNRKDM-VLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKE 5679
Query: 1219 ----------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKE 1070
E K E E+ + MN + + L + L+ ++ K KE
Sbjct: 5680 NTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKE 5739
Query: 1069 DLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQL 890
++ QL S L + N M ++N +K+L KD+ + E Q + +
Sbjct: 5740 IIMKARSQLDRRQSELDKQQTNMNDIME----TMKNERKQL--DKDKEEMEE-QKQEMEK 5792
Query: 889 ELKHANMSICSLSEKIQQIEEREKVL---LTQLSTKDTDMQHLAAQLTLAQEEISSTKEM 719
E + + S SL E ++ ++ +++V+ +L +++ A + +EE + +++
Sbjct: 5793 ERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQI 5852
Query: 718 LKDFIDNME---------ASDTNLQSHFNQIQEM-LLNQNVNYPLEATVNIGFDQSMDEA 569
L+ + ++ A DT + N + EM + N++ L+ +++E
Sbjct: 5853 LEKMAEELKKERKDVAHLAEDTKREK--NSLDEMKVANESSMADLQKE-----KSNLEEM 5905
Query: 568 VSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
I +K TEDI E +++E+ +LQ+++ QS ++ K
Sbjct: 5906 KENI------SKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEK 5948
Score = 90.5 bits (223), Expect = 3e-15
Identities = 133/649 (20%), Positives = 269/649 (41%), Gaps = 30/649 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD + ++ K++ D+ ET+KN + LD +++ +++ EI + ++ S
Sbjct: 3781 LDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDED 3840
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEE---SISVLKQELSSARLQIESLEKELNQANEEV 1892
LK +K +Q E +++ E +K ELE I +K+E+ + R +E + +EL + E
Sbjct: 3841 LKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESF 3900
Query: 1891 KVL---SKFRYQVL-ELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKE 1724
L +K ++L E++ ++ L A+L K ++ + + ++ +E + +E
Sbjct: 3901 THLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLRE 3960
Query: 1723 VEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEES 1544
E Q + + +R + + +E + +A I ++ D+ +S+D A K +
Sbjct: 3961 DELGQLQAEIHKQQREIEKEKSNIESERAA----IIKIVEDLQHKIISLDRDAESLKLDR 4016
Query: 1543 TKVSNACDLLQ----EIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSN 1376
N ++L+ E+E EI + K+ Q R VEE ++ +ET N
Sbjct: 4017 EAFENEREVLKQMKTELERETDEIE-KIKLETQHERQRVEEMTA---------DFMETMN 4066
Query: 1375 TMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQM- 1199
+ L+ + E K + D D +Q +E E+ K +QM
Sbjct: 4067 N-ERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMK 4125
Query: 1198 -------EEYKMLQAELNN---WLSCMNAEMGKFLCLCNSMVYLEGDI---LKYKEDLLL 1058
+E + ++ E N L M E+ K S +L D K + + +
Sbjct: 4126 IELEKEADEIRKIKEETQNERQRLEKMTEELKKEK---ESFTHLAEDTKTEKKILDKMKV 4182
Query: 1057 NHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKH 878
+ L A++ K L E + D E ++++ + +D + + Q E+K
Sbjct: 4183 ANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQLQAEIHKQQGEIK- 4241
Query: 877 ANMSICSLSEKIQQIEEREKVLLTQLSTKDT-DMQHLAAQLTLAQEEISSTKEMLKDFID 701
EK ER ++ KD D+QH L E + +E ++ +
Sbjct: 4242 --------MEKSNNESERAAII------KDVKDLQHKMFSLDRDLESLKLDREAFENERE 4287
Query: 700 NMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTED 521
++ T+L+ +I+++ L + Q ++E ++I K+ +
Sbjct: 4288 VLKQIKTDLKRKAEEIEKIKLETQHD-----------RQRVEEMTAQI------QKERDK 4330
Query: 520 INTEIAHTSDKD----EEVIKLQSQVENLQSLVQMLKQQNTKLELLAKK 386
IN I T+ KD E +++ +++ ++S ML+++ LE K
Sbjct: 4331 INNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSK 4379
Score = 84.0 bits (206), Expect = 3e-13
Identities = 137/676 (20%), Positives = 281/676 (41%), Gaps = 48/676 (7%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDL-DIEQKLSTDRQSEIYSLS-AELER---ITQ 2078
L R DI+K E K ++ + +L D + +L DR + ++ EL+R + +
Sbjct: 8602 LQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRE 8661
Query: 2077 SEQMSLKRLKEAEQTLL---EAESERESLK-------------AELEESISVLKQELSSA 1946
+E + K L++ EQ + + E++ E+L+ A+ E++ +Q+L
Sbjct: 8662 TEDLERKILQQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLL 8721
Query: 1945 RLQIESLEKELNQA--NEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFD 1772
+ ++S E EL EE K L + + + E + ++S ++ +Y + +L
Sbjct: 8722 QGALQSQESELENRVFMEEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQR 8781
Query: 1771 KKNEITCLQEVIEQKEVE--------ERQRECMLAASERSNDINVNALEKKLSA---YEG 1625
+K ++ + IEQ++ + ERQ E + D NALEK S +
Sbjct: 8782 EKEQLEISKNQIEQEKKDLQNMKSNLERQLESLRHEKANVED-EKNALEKMRSESKEIQN 8840
Query: 1624 KIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARH 1445
IR+ D+ + ++ +EE+ ++ + ++++++ L++ R + ++ +
Sbjct: 8841 AIRKEREDLENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINN 8900
Query: 1444 NVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXX 1265
+EE + + K ++E + D E + D K
Sbjct: 8901 KMEELLQMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQE--- 8957
Query: 1264 XXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDI 1085
+ E K + +E K L E+ + + EM + +G +
Sbjct: 8958 ------------KEREIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLL 9005
Query: 1084 LKYKEDLLLNHGQLRAEMSSL---KIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAE 914
K K++L +L +M L K E E+ + +E+++KE I K++ + +
Sbjct: 9006 EKEKQELKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEK 9065
Query: 913 GQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTK-DTDMQHLAAQLTLAQEE- 740
+ QL++ L+++ ++ ++EK L Q + + Q L T EE
Sbjct: 9066 SNIEEMQLKIFKQQR----LNDQTREENKKEKESLEQQRFETEQQKQMLEISTTKMMEEK 9121
Query: 739 -----ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMD 575
+S + KD ++ + A TN + H + + L+ + +E I D+
Sbjct: 9122 NEMADLSRELQKAKDELEKI-AYKTNKERHEVEQMQAELHSQIQ-AIEQQGQIMQDKQNH 9179
Query: 574 EAVSEIAVQTFPNK---DTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTK- 407
E+++Q + + E H ++ EE K Q +E +++ +++ KQ+N K
Sbjct: 9180 LEEKELSIQRKEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQKNNKD 9239
Query: 406 LELLAKKTSEMDPEKY 359
ELL K SE++ EKY
Sbjct: 9240 FELLEKIRSELENEKY 9255
Score = 81.6 bits (200), Expect = 1e-12
Identities = 127/652 (19%), Positives = 275/652 (42%), Gaps = 31/652 (4%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIE-QKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++ +K+I E+ + + DL E K S D + ++ + E E + ++ K ++
Sbjct: 3594 EMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLTEKELLESDRKLLKKDVE 3653
Query: 2047 EAEQTLLEAESERESLKAE---LEESISVLKQELSSARLQIESLEKELNQANEEVKVLSK 1877
+Q LL ES+ ESLK + LE VLKQ + + + E +EK + E + + +
Sbjct: 3654 NLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEE 3713
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIE--QKEVEERQRE 1703
Q+ + EY Q+++ ++++ D +Q+ K++E+ L+ I+ Q+E+E+ +
Sbjct: 3714 MTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQELEKEKEI 3773
Query: 1702 CMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSV---------------DFS 1568
M SE D+ + L+K+ + I ++N+ QL DF
Sbjct: 3774 IMKDRSEL--DLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFD 3831
Query: 1567 AG--VFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKS 1394
G E+ + + +E +N L ++++E + E R EE + + LE +
Sbjct: 3832 QGRNSLDEDLKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTE 3891
Query: 1393 QLETSNTMDHDTLSSTHQGSMEDKASSQSSTGD----NDPKAXXXXXXXXXXXECRQNL- 1229
+L+ + S TH ED Q + N+ E R+N+
Sbjct: 3892 ELK------REKESFTHLA--EDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENIS 3943
Query: 1228 -ENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNH 1052
+ E+ K+K+ E ++ + EL + ++ + + +++ I+K EDL
Sbjct: 3944 KQTEDVKNKK-ENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKI 4002
Query: 1051 GQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHAN 872
L + SLK+ ++ F EN ++ L K + + +LE +H
Sbjct: 4003 ISLDRDAESLKL---DREAF--------ENEREVLKQMKTELERETDEIEKIKLETQHER 4051
Query: 871 MSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNME 692
+ ++ + E+ QL+ +MQ ++ + ++ +++ L + M+
Sbjct: 4052 QRVEEMTADFMETMNNER---KQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMK 4108
Query: 691 ASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINT 512
++ N++++M + EA + + T K ++ T
Sbjct: 4109 LQKQVIEEEKNKLEQM----KIELEKEADEIRKIKEETQNERQRLEKMTEELKKEKESFT 4164
Query: 511 EIAHTSDKDEEVI-KLQSQVENLQSLVQMLKQQNTKL-ELLAKKTSEMDPEK 362
+A + +++++ K++ E+L + +Q K ++ E ++K+T + + EK
Sbjct: 4165 HLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEK 4216
Score = 79.7 bits (195), Expect = 5e-12
Identities = 122/685 (17%), Positives = 295/685 (43%), Gaps = 64/685 (9%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
+I+KEK KE + + + +I + T+R+ E+Y + +ELER+ K+L +
Sbjct: 10395 EIKKEKE-----KENEEEEEEEEEIRVIVETERK-ELYQIKSELERVRSEIDHEQKKLND 10448
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSA--RLQIESLEKELNQANEEV--KVLSK 1877
+ + + + + E +K+E+ + +++E S ++Q +LEK + ++E+ K++ +
Sbjct: 10449 YMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVE 10508
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECM 1697
Q +++ ++L + K+ ++ + ++ +NE +++V E+ +++RE +
Sbjct: 10509 VEEQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKKVDEE---IKKERETL 10565
Query: 1696 LAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDL 1517
R +I++ +++L + + +R + D+ +++ ++ E+ + N DL
Sbjct: 10566 -----REMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDIN-------EQKLHLKNQRDL 10613
Query: 1516 LQEIENFLREIRVETKVTIQEARHNVEEFSSVV--KHLEYLKSQLETSNTMDHDTLSSTH 1343
L+ + R E + + + ++EF + V + + K ++E +T +
Sbjct: 10614 LE-------QEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARII 10666
Query: 1342 QGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECK---SKQMEEYKMLQAE 1172
+ M+ KA Q + + + + EE + + EE +++E
Sbjct: 10667 E--MKTKAELQEIMQEKEEE------------------DEEEMRVIVEMEREELNQIKSE 10706
Query: 1171 LNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSL---------- 1022
L S ++ E K + + D+ K K +++ Q+ E S L
Sbjct: 10707 LKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLE 10766
Query: 1021 KIELVEKNGFMGYAVLDVENVQKELLIWK-----DRAMIAEGQSKAFQ--LELKHANMSI 863
+ ++ + ++ VE +K++ + K +R IA+ Q Q +L++ N I
Sbjct: 10767 RHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERI 10826
Query: 862 CSLSEKI---------------QQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISST 728
+ E+I ++ EE V+ K D++ ++ + +++ +
Sbjct: 10827 KEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDVNKQNQDLMNQ 10886
Query: 727 KEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEA---VSEI 557
+++LK + + T LQ ++ + Q + +S++E + E+
Sbjct: 10887 RDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEM 10946
Query: 556 AVQTFP-----NKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLV-----------QML 425
+T P K+ E+ A K EE+ +++SQ+E ++S + +M+
Sbjct: 10947 KTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMI 11006
Query: 424 KQQNTKLEL----LAKKTSEMDPEK 362
+Q+ LE + K+ +M+ E+
Sbjct: 11007 EQEKEDLEKMKSEIMKQRQQMEEER 11031
Score = 78.6 bits (192), Expect = 1e-11
Identities = 129/680 (18%), Positives = 300/680 (44%), Gaps = 61/680 (8%)
Frame = -2
Query: 2227 LDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++IQKE+ I E LK + + DL+ E+ +++I SLS +L+ ++ E + R +
Sbjct: 3114 VEIQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI-SLSEDLKEQSEREGIDNTRTR 3172
Query: 2047 ----------------------EAEQTLLEAESER-ESLKAELEESISVLKQELSSARLQ 1937
E ++ ++E E ++ E +KAEL++ K EL + R
Sbjct: 3173 IKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNERQN 3232
Query: 1936 IESLEKELNQANEEVKVLSK--FRYQV----LELEEYSQQLSADLSKVHEDYSAALRQLF 1775
+E +L + E V+ L++ R QV +++E Q+ + + +K ++ L +L
Sbjct: 3233 LEEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQE--RVLIELK 3290
Query: 1774 DKKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVS 1595
+I +E +E + +EER++ + A ++ + L++ +S + I N
Sbjct: 3291 KTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDI---VNKTE 3347
Query: 1594 QLTLS----VDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFS 1427
QL L A +++++ +N ++ E + L + E +E +E S
Sbjct: 3348 QLRLREVELEQLQALIYRQQDEIEANRKAIINE-KYRLEGQKTEIDRLQREVNQMMEYAS 3406
Query: 1426 SVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSS-TGDNDPKAXXXXXXXXXX 1250
+LE KS++ + D + +G +E++ ++ + D K
Sbjct: 3407 KDRANLEKEKSEM-IAQKHQMDIELNKERGLIEERTQMLNTYEKEMDQKRTALEVEMKEL 3465
Query: 1249 XECRQNLENEECKSKQM--------EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLE 1094
+Q ++ E+ K +QM ++ K L+ + N + + + +L
Sbjct: 3466 KYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLAHLA 3525
Query: 1093 GDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAE 914
D + +++ + H A++ K L + M +++ +K++++ +D+ +
Sbjct: 3526 EDTKRKDDEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQQMQ 3585
Query: 913 GQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEIS 734
+ Q E+ SI + + + ++ + L+T+L+ + D++ ++ +E +
Sbjct: 3586 AEINRQQTEM-DTKKSI--IENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLTEKELLE 3642
Query: 733 STKEMLKDFIDNMEASDTNLQS---HFNQIQEMLLNQ---------NVNYPLEATVNIGF 590
S +++LK ++N++ ++S Q +E+L N+ ++ E I
Sbjct: 3643 SDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKL 3702
Query: 589 D-----QSMDEAVSEIAV-QTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQM 428
+ Q ++E ++I + + K ++I EI +++++ + Q +++ L++ +Q
Sbjct: 3703 ETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQN 3762
Query: 427 LKQQNTK-LELLAKKTSEMD 371
L+Q+ K E++ K SE+D
Sbjct: 3763 LQQELEKEKEIIMKDRSELD 3782
Score = 76.3 bits (186), Expect = 5e-11
Identities = 150/706 (21%), Positives = 304/706 (43%), Gaps = 71/706 (10%)
Frame = -2
Query: 2233 VRLDIQKEKNISEDLKET-------VKNLQSDLDIEQKLSTD--------------RQSE 2117
+++++QK+KN E+L+ T V+N + LD +QK D +SE
Sbjct: 13462 LQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSE 13521
Query: 2116 IYSLSAELERITQSEQMSLKRLKEAEQTLLE-----AESERESLKAE------LEESISV 1970
+ LS L Q EQ L+RL E E+ +E ESE++S++ E L+E + V
Sbjct: 13522 LNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIESEKQSIERERAELKRLKEEVEV 13581
Query: 1969 ------LKQELSSARLQIESLEKELNQANEEVKVL-SKFRYQVLELEEYSQQLSADLSKV 1811
L+Q+ + + + E LE E + EE+ L + + + EL+ ++++ A K
Sbjct: 13582 QHERTLLQQDKNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEA---KR 13638
Query: 1810 HEDYSAALRQLFD----KKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKK 1643
E+ L + + K E L+E I +K+ + ++ L + R + +L++
Sbjct: 13639 QEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQ-TSLDEI 13697
Query: 1642 LSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREI-RVET-- 1472
E + R LE V+ + V K E T S ++ + N ++E+ R++T
Sbjct: 13698 TKTDERRQRALEETVA----TTAKQPIVIKLEDTLTSEVQEMRDHLNNEIKELARMKTIM 13753
Query: 1471 ---KVTIQEARHNV----EEFSSVVKHLEYLKSQLE---TSNTMDHDTLSSTHQGSMEDK 1322
K +++A+ ++ EEF ++ KS+ E T D + LS+T +
Sbjct: 13754 KMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLD---KKN 13810
Query: 1321 ASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNA 1142
+++T K + ++N+ENE + KQ+E+ + +Q + + ++
Sbjct: 13811 KEIENNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQIEQEREIQRKAD--VTSTEK 13868
Query: 1141 EMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVE- 965
EM Y E + YK +L + +++ + S +EL + + + +
Sbjct: 13869 EM-----------YTEK--VTYKTELEDSKEKIKPDRDS-TLELTDTDSAKTDGEREAQT 13914
Query: 964 ---NVQKELLIWKDRAMIAEGQSKAFQ------LELKHANMSICSLSEKIQQIEEREKVL 812
VQ L + D E + LEL A + L E+ + EE + V+
Sbjct: 13915 LETKVQDVLQLTDDTTQDQEELHDEMENKMKIILELNKAKKDLQKLKEECRSAEEEKSVI 13974
Query: 811 LTQLSTKDTDMQHLAAQ-LTLAQE--EISSTKEMLKDFIDNMEASDTNLQSHFNQIQEML 641
+ L + ++ + ++ L+L QE ++ K ++ M+ ++ + + ++
Sbjct: 13975 MESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWE--TDVQ 14032
Query: 640 LNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKD-EEVIKLQ 464
+ Q P+E T +I +S +E ++ Q K + + +E+ D + E+V +++
Sbjct: 14033 IQQEGQEPIETTGHI-TKKSEEEISAKKTKQPIVTKLEDTLTSEVQEMRDMEIEDVARMK 14091
Query: 463 SQVENLQSLVQMLKQQ-NTKLELLAKKTSEMDPEKYFHFEELCQSL 329
+ ++ + ++ K ++E + E EK + E L Q L
Sbjct: 14092 TMMKMEKDQLEQAKSDIQRQMEEFERNMEETLKEKSRNEETLLQLL 14137
Score = 75.9 bits (185), Expect = 7e-11
Identities = 131/629 (20%), Positives = 268/629 (42%), Gaps = 25/629 (3%)
Frame = -2
Query: 2227 LDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++IQKE+ I E LK + + DL+ E+ +++I SL ELE ++ E + R++
Sbjct: 2720 VEIQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI-SLREELEEQSEKEGIDKTRVR 2778
Query: 2047 EAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRY 1868
+Q + E E R ++ ELE + + KQ + R +IE ++ EL +E K K R
Sbjct: 2779 -IKQEMDELEQTRLNVVKELENN-ELQKQIIEDERDKIEQIKAEL---QKEAKDTEKQRQ 2833
Query: 1867 QVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIE------QKE------ 1724
+ ++++ L +D + ++ D++ + L++ +E +KE
Sbjct: 2834 DIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDLKK 2893
Query: 1723 --VEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
E + E L + R ++I + ++K+ E +L+ +S+ ++ F++
Sbjct: 2894 TNTEMKDLEKQLESQNRQHEIQLAEIQKEREILE----QLKLTLSKQKEDLEKERDCFEK 2949
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFS-SVVKHLEYLKSQLETSNT 1373
E +S +L ++ E RE +T+V I++ +++ +VVK LE +N
Sbjct: 2950 EKADISLREELQEQSE---REGIGKTRVRIKKEMDELKQTRLNVVKELE--------NNE 2998
Query: 1372 MDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEE 1193
+ + + KA Q D + + E L+NE+ K +
Sbjct: 2999 LQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEK-KDIETST 3057
Query: 1192 YKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIE 1013
++ E N + E + +++ D+ K K ++ QL +++ +I+
Sbjct: 3058 DRIRDEEANLEVQKQRLESDR-----DTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQ 3112
Query: 1012 LVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELK--HANMSICSLSEKIQ 839
LVE +QKE I + + Q + + E + SLSE ++
Sbjct: 3113 LVE--------------IQKEREILEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLK 3158
Query: 838 QIEEREKV--LLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSH 665
+ ERE + T++ + +++ L QE K++++D D +E L+
Sbjct: 3159 EQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKE 3218
Query: 664 FNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEI---AHTS 494
+ + L N+ N EA + D+ E+++E + + I TE+ A+ S
Sbjct: 3219 AEKTKLELQNERQNLE-EAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANES 3277
Query: 493 DK---DEEVIKLQSQVENLQSLVQMLKQQ 416
+K + +I+L+ V ++ + L+ Q
Sbjct: 3278 NKQMQERVLIELKKTVTDIAGAKEDLENQ 3306
Score = 75.9 bits (185), Expect = 7e-11
Identities = 137/684 (20%), Positives = 276/684 (40%), Gaps = 75/684 (10%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L ++ ++ KEK E++K+ VK + ++ E++ + + + I +
Sbjct: 8525 LQQMKNELNKEKEQVEEMKQMVKTERVKIEQEKE----------EMRKQTQEIEDGHEKL 8574
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVL 1883
K+ + A++ L +A SE + LK +L + + +Q++ ++E+ ++ L++ + E+
Sbjct: 8575 QKKTEIADKLLQDANSESDRLK-DLSMKLQMQRQDIEKTNTEMETKKRSLDRMSREL--- 8630
Query: 1882 SKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRE 1703
Q L + Y + L K+ E+ E +E+K +++R+++
Sbjct: 8631 --------------QDDKIRLKNDRDAYEKDMTHLELKREELVRETEDLERKILQQREQD 8676
Query: 1702 CMLAASERSNDINVNALE-------KKLSAYEGKIRRLENDVSQLTL--------SVDFS 1568
M ++R + ALE KK + + ++ + ++ +L L +
Sbjct: 8677 EM---AKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQESELE 8733
Query: 1567 AGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQL 1388
VF EE + A +E L E+ E R +EE + LE K+Q+
Sbjct: 8734 NRVFMEEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQREKEQLEISKNQI 8793
Query: 1387 ETSNTMDHDTLSSTHQGSME----DKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLEN- 1223
E D + S + +E +KA+ + + + R++LEN
Sbjct: 8794 E-QEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENC 8852
Query: 1222 ---EECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNH 1052
E + K+MEE + +++E+ K ++ E I E+LL
Sbjct: 8853 WVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSR---ENIESREEKINNKMEELL--- 8906
Query: 1051 GQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDR------AMIAEGQ------ 908
Q++ EM K E+ +++ + A +D+EN + E+ +D+ I E +
Sbjct: 8907 -QMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQ 8965
Query: 907 --------SKAFQLELKHANMSICSLSEKIQQIE------EREKVLLTQLSTK-DTDMQH 773
S+ +L++K M + + + Q+IE E+EK L Q + + M
Sbjct: 8966 LDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMD 9025
Query: 772 LAAQLTLAQEE---ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLL----NQNVN--- 623
L + +EE + + K L+D E L + I+EM L Q +N
Sbjct: 9026 LTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQT 9085
Query: 622 -----YPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTE--DINTEIAHTSDKDEEVI--- 473
E+ F+ + + EI+ + E D++ E+ D+ E++
Sbjct: 9086 REENKKEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDELEKIAYKT 9145
Query: 472 -KLQSQVENLQ----SLVQMLKQQ 416
K + +VE +Q S +Q ++QQ
Sbjct: 9146 NKERHEVEQMQAELHSQIQAIEQQ 9169
Score = 75.1 bits (183), Expect = 1e-10
Identities = 124/623 (19%), Positives = 263/623 (42%), Gaps = 12/623 (1%)
Frame = -2
Query: 2203 ISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTLLE 2024
I ++KE +K ++SD D+ +K D + L E + K+ + L E
Sbjct: 4348 IKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLE----------KQRKIKLAE 4397
Query: 2023 AESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQVLELEEY 1844
+ ERE L+ ++ E ++ ++ Q++ + EL+Q E++ L + ELE+
Sbjct: 4398 IQKEREDLE-KMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQQ------ELEKE 4450
Query: 1843 SQQLSADLSKVHEDYSAALRQL-FDKKNEITCLQEVIEQKEVEERQRECMLAASERSNDI 1667
+ + D S++ LRQ DK+ T + +++E + E +Q L + +
Sbjct: 4451 KEIIMKDRSQLD------LRQSELDKQQ--TNVNDIMETMKNERKQ----LDKDKEETEE 4498
Query: 1666 NVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLRE 1487
+EK+ ++ + L+ D+ + L V ++E +K+ + E+E E
Sbjct: 4499 QKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQ----VLEDEKSKLE---QMKIELEREAVE 4551
Query: 1486 IRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQS 1307
IR + K IQ R N+E+ + +K ++ N D + ++ ++ D +S
Sbjct: 4552 IR-KIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKS 4610
Query: 1306 STGDNDPKAXXXXXXXXXXXECRQNL--ENEECKSK------QMEEYKMLQAELNNWLSC 1151
+ + R+N+ + E+ ++K + +E + LQAE++
Sbjct: 4611 NLEE-----------------MRENISKQTEDVENKKENLRLREDELRQLQAEIHK---- 4649
Query: 1150 MNAEMGKFLCLCNSMVYLEGD---ILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYA 980
E+ K + +E + I+K EDL L + SLK+ ++ F
Sbjct: 4650 QQREIEK------EKINIESERAAIIKDVEDLQHKIICLDRDAESLKL---DREAF---- 4696
Query: 979 VLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQL 800
EN ++ L K + + +LE +H + ++ +IQ+ + L+ +
Sbjct: 4697 ----ENEKEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDEINNLIEET 4752
Query: 799 STKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNY 620
+ KD + + + I S K+ML+ ++E + +S +++E L Q N
Sbjct: 4753 NRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKT----RSELYKVKEDLEKQKENT 4808
Query: 619 PLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQS 440
E + M+E ++ ++ +I + + K +E+ +L+++++NLQ
Sbjct: 4809 LAEIQKEREDLEKMNENIT---------REMHEIKHQEEQMNQKQDELDQLKTEIQNLQQ 4859
Query: 439 LVQMLKQQNTKLELLAKKTSEMD 371
++ K E++ K S++D
Sbjct: 4860 ELEKEK------EIIMKDRSQLD 4876
Score = 75.1 bits (183), Expect = 1e-10
Identities = 131/671 (19%), Positives = 280/671 (41%), Gaps = 33/671 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD ++ ++Q E E++K + +++++ EQ+ + I +LE + +
Sbjct: 9496 LDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGDLEIMRADYE-- 9553
Query: 2062 LKRLKEAEQTLLEAESERESL---KAELEESISVLKQELSSARLQIESLEKELNQANEEV 1892
K+ ++ E+ +EA+ ER+ L K+ELE+ + + E +EKE N
Sbjct: 9554 -KQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKERNDLE--- 9609
Query: 1891 KVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQ--KEVE 1718
K+ S+ Q ++E+ +L + + + + K++I +E++E+ EVE
Sbjct: 9610 KMKSELMTQRQQMEDERSELDQKIKEANTE-----------KDKIEKNKEIVERLMAEVE 9658
Query: 1717 ERQRECML----AASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
E++ + L A ER N ++ L L+ E +++ + + E
Sbjct: 9659 EQRNDFKLKKEELALERQNIVDEKYL---LAQCETELQNKSEQIRNM------------E 9703
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTM 1370
E+ K N + L+E E L+ + E K I+E E+ + + K +L+
Sbjct: 9704 EAVK--NERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKK-- 9759
Query: 1369 DHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEY 1190
DTL + Q + D + R+ E + K+MEE
Sbjct: 9760 --DTLEQEREEINHKWTQFQQRIDEFDAQV-------------RKQKEEDLTNQKKMEEE 9804
Query: 1189 KMLQAELNNWLSCMNA----EMGKFLCLCNSMVYLEGDILKYKED---LLLNHGQLRAEM 1031
+ E+N + M E + + L+ I+K KE + + R ++
Sbjct: 9805 RKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAMTIKLKMEREDL 9864
Query: 1030 SSLKIELVEKNGFMGYAVLDVENVQKEL-----LIWKDRAMIAEGQSKAFQLELKHANMS 866
+K ELV + +V++ QK+L +I +++ + + +S+ + +
Sbjct: 9865 DQIKSELVREK-------TEVDHEQKKLNDDIKMIEQEKEDLEKMKSE-IMTQKQEMEKE 9916
Query: 865 ICSLSEKIQQIE------EREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFI 704
L KIQQ + E+ K ++ +L + + +H ++ L +EE+ ++ + D
Sbjct: 9917 RSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRH---EIQLQKEELDIERQKIADEQ 9973
Query: 703 DNMEASDTNLQSHFNQIQEMLLNQNVNYPLEA--TVNIGFDQSMDEAVSEIAVQTFPNKD 530
D + + + LQ+ +I+ +N+ + E + ++ +E S +D
Sbjct: 9974 DLLIQNKSELQNENERIRN--INEVIKKERETLKEMEAHLEKEKEEMKSITEETRRQKED 10031
Query: 529 TEDINTEIAHTSDKDEEVIK----LQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEK 362
E ++T+I +++++++K L+ + E++ L+Q+ + + K E D K
Sbjct: 10032 LEKMSTDI---KEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQVSKQKEEDLTK 10088
Query: 361 YFHFEELCQSL 329
+E +SL
Sbjct: 10089 QKEMKEERKSL 10099
Score = 75.1 bits (183), Expect = 1e-10
Identities = 132/702 (18%), Positives = 287/702 (40%), Gaps = 68/702 (9%)
Frame = -2
Query: 2245 TLDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLST-------DRQSEIYSLSAELER 2087
TL + ++KEK + + E + + DL +K+ST D +S+ L E E
Sbjct: 11395 TLKEMEAYLEKEKEEMKSITEETRRQKEDL---EKMSTHINEQKQDLRSQRDLLEQEREE 11451
Query: 2086 ITQSEQMSLKRL--------KEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIE 1931
I + +R+ K+ E+ L + + +E K+ E ++L+ + + + E
Sbjct: 11452 INHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMK---TKAEPE 11508
Query: 1930 SLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITC 1751
++KE + EE ++ K + E+E Q+ + L +V + ++L D K I
Sbjct: 11509 EIKKEKEKEEEEQEMRVKVEMERKEIE----QIKSQLERVRSEMDHEQKKLNDDKKMIEQ 11564
Query: 1750 LQEVIE--QKEVEERQRECMLAASERSNDINVNALEK-KLSAYEGKIRRLENDVSQLTLS 1580
+E +E + E+ +++++ SE I LEK + + + +L +V +
Sbjct: 11565 EKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHE 11624
Query: 1579 VDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYL 1400
+ F E K+++ DLL ++ K+ Q ++E +K
Sbjct: 11625 IQFQKEELDIERQKIADEQDLL-----------IQNKIEQQNENERIKEMDEEIKKERET 11673
Query: 1399 KSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE 1220
++E + + + + S + + K + + D + + +Q+L N+
Sbjct: 11674 LKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQ--------------KQDLMNQ 11719
Query: 1219 ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGD-----------ILKYK 1073
KQ E E+N+ L+ + + +F N +V + + +K
Sbjct: 11720 RDLLKQERE------EMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEY 11773
Query: 1072 EDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQ 893
E ++ + R E+ ++++ ++N + +E +K+ K+R E Q +A
Sbjct: 11774 ESIIEETNRKRTELEEIEVDQSQQNKNVETMKDLLEKERKD--TEKER---EELQKQADD 11828
Query: 892 LELK------HANMSICSLSEKIQQIEEREKVLLTQ---LSTKDTDMQHLAAQLTLAQEE 740
LE++ MS SL E+ + +E++ +L Q L + DM +L Q+E
Sbjct: 11829 LEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKE 11888
Query: 739 ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSE 560
I + K +++ +E + +++E L N V + +++ + + E
Sbjct: 11889 IQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKHQQQ-IEE 11947
Query: 559 IAVQTFPNKDTED----------------------INTEIAHTS---DKDEEVIKLQSQ- 458
+ V+T +D D + E+ T D EE +KL+ Q
Sbjct: 11948 MRVKTKMERDELDQLMAKMLMDRKENERSKDMIGLLKKEMEQTKFNLDAQEEELKLEKQK 12007
Query: 457 VENLQSLVQM----LKQQNTKLELLAKKTSEMDPEKYFHFEE 344
++N + ++M +K++ ++++ L ++ E D + + +E
Sbjct: 12008 IQNEKKDLEMFKAEIKREASEVKTLKEQQLEKDTKAFEALKE 12049
Score = 75.1 bits (183), Expect = 1e-10
Identities = 125/644 (19%), Positives = 282/644 (43%), Gaps = 28/644 (4%)
Frame = -2
Query: 2218 QKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELE-RITQSEQMSLKRLKEA 2042
+KEK+ +++ ++++S ++ +L T+ ++I +++EL+ R + E + K+ KE
Sbjct: 12912 RKEKHAEAEIQRQFEDIES---VKVRLVTE-SNQIDKMNSELKTRSEELENLIKKQQKEF 12967
Query: 2041 EQTLLEAESERESLK---AELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFR 1871
E E + ER++L+ AELE + LK ++ + L+KE N+ E +L + +
Sbjct: 12968 ETKENEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREK 13027
Query: 1870 YQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-----TCLQEV-IEQKEVEERQ 1709
++ + + QQ ++ + + + + L +NE+ + L + +E+ E+++ +
Sbjct: 13028 SELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLK 13087
Query: 1708 RECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSN 1529
E + + + S + L++ E K +L+N + ++ + + +E+ +
Sbjct: 13088 TE--IQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMD---KLSIQREKDSLEEI 13142
Query: 1528 ACDLLQEIENFLREIRVETKVT--IQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTL 1355
DL ++ E E+R ++T I + +++ + L +++ +E + L
Sbjct: 13143 KADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQAKI----L 13198
Query: 1354 SSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSK-QMEEYKMLQ 1178
S Q +K + S +ND R++LE + ++ ++E + +
Sbjct: 13199 ESDVQLLQTEKEILEKSKTEND--------------LLREDLEKQRKRNDLTLQELRKEK 13244
Query: 1177 AELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKN 998
L ++ + E L N V L+ LK KE L + R EM L+++L +
Sbjct: 13245 MALEQMITDITKEKDAVASLQNE-VSLKQHELKNKETEL---DEQRKEMDDLRMQLEMRQ 13300
Query: 997 GFMG-----YAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELK----HANMSICSLSEK 845
V VEN++ + + ++ E + + Q +K N+ S ++
Sbjct: 13301 NSTNKQQQEVDVFIVENMKMRNDLESMKTLLDE-ERRQLQDNIKTFEDQKNVLHPSKTDA 13359
Query: 844 IQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSH 665
+QQ +E EK T + T+ ++ ++ + +EI +KE L+ +E +
Sbjct: 13360 VQQTDELEK-FTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGK 13418
Query: 664 FNQIQEMLLNQNVNYPLEATVNIGFD--QSMDEAVSEIAVQTFPNKDTEDINTEIAHTSD 491
QI+ + L A + G D +++ + ++A++ K ++ + +
Sbjct: 13419 RAQIESL-------EQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKN 13471
Query: 490 KDEEVIKL----QSQVENLQSLVQMLKQQNTKLELLAKKTSEMD 371
+ EE+ + QVEN + + + KQQ +++ SE D
Sbjct: 13472 ELEELRNTIEAEKHQVENRK--IMLDKQQKEVEDIMTVIKSERD 13513
Score = 72.8 bits (177), Expect = 6e-10
Identities = 145/702 (20%), Positives = 296/702 (42%), Gaps = 82/702 (11%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSE--------- 2072
+IQKE+ I E LK T+ + DL+ E+ +++I SL EL+ ++ E
Sbjct: 2918 EIQKEREILEQLKLTLSKQKEDLEKERDCFEKEKADI-SLREELQEQSEREGIGKTRVRI 2976
Query: 2071 --------QMSLKRLKEAEQTLLE---AESER---ESLKAELE---ESISVLKQELSSAR 1943
Q L +KE E L+ E ER E +KAEL+ E ++++ R
Sbjct: 2977 KKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDR 3036
Query: 1942 LQIESLEKELNQANEEVKV-LSKFRYQVLELEEYSQQLSAD-----------------LS 1817
E + +L ++++ + R + LE Q+L +D +
Sbjct: 3037 RNNEEMVIKLQNEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKERFDLEKTKTEMG 3096
Query: 1816 KVHEDYSAALRQLFDKKNEITCLQEVIE--------QKEVEERQRECMLAASERSNDINV 1661
+ + + +RQ + EI +E++E QKE E++R+C + DI++
Sbjct: 3097 NLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCF---EKEKADISL 3153
Query: 1660 NALEKKLSAYEGKIRRLENDVSQLTLSVD----FSAGVFKEESTK------VSNACDLLQ 1511
+ K+ S EG ++N +++ +D + KE+ + + D ++
Sbjct: 3154 SEDLKEQSEREG----IDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIE 3209
Query: 1510 EIENFLREIRVETKVTIQEARHNVEEFSSVVK----HLEYLKSQLETSNTMDHDTLSSTH 1343
+I+ L++ +TK+ +Q R N+EE + +K ++E L +L + + T
Sbjct: 3210 QIKAELKKEAEKTKLELQNERQNLEEAGTKLKKDRENVESLAEELGRKQVVLENMQIET- 3268
Query: 1342 QGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNN 1163
M+ KA ++S+ + +++LEN+ + + E+ K+ QAE+
Sbjct: 3269 --EMQRKA-NESNKQMQERVLIELKKTVTDIAGAKEDLENQLLEER--EKNKVKQAEI-- 3321
Query: 1162 WLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQL----------RAEMSSLKIE 1013
AE L + + DI+ E L L +L + E+ + +
Sbjct: 3322 -----QAEKDMLYLLKQGISEQQVDIVNKTEQLRLREVELEQLQALIYRQQDEIEANRKA 3376
Query: 1012 LVEKNGFMGYAVLDVENVQKEL-----LIWKDRAMIAEGQSKAFQLELKHANMSICSLSE 848
++ + + +++ +Q+E+ KDRA + + +S+ + KH M I L++
Sbjct: 3377 IINEKYRLEGQKTEIDRLQREVNQMMEYASKDRANLEKEKSE--MIAQKH-QMDI-ELNK 3432
Query: 847 KIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQS 668
+ IEER ++ L+T + +M L + +E+ K+ +++ + ++ LQ
Sbjct: 3433 ERGLIEERTQM----LNTYEKEMDQKRTALEVEMKELKYHKQAIQEEKNKLQQMKIELQR 3488
Query: 667 HFNQIQEML-LNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSD 491
+ I+++ +N LE ++ D+ ++ +A T D + E A +D
Sbjct: 3489 EADDIKKLKEKTRNERQSLEKMAE-NLEKEKDD-LAHLAEDTKRKDDEMKVLHESA-LAD 3545
Query: 490 KDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPE 365
+E L+ E++ +M+ + K+ L K +M E
Sbjct: 3546 IQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQQMQAE 3587
Score = 70.9 bits (172), Expect = 2e-09
Identities = 105/631 (16%), Positives = 253/631 (40%), Gaps = 12/631 (1%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L+ V +IQ+EK + + + +L+ + +RQ +I + +LE E+
Sbjct: 9303 LNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLE-----EEKL 9357
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEES-ISVLKQELSSARLQIESLE---KELNQANEE 1895
L +++ + E +R+ K E+ E+ + V+K++ +AR + E + +E Q NE
Sbjct: 9358 LVQIEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNEN 9417
Query: 1894 VKVL-----SKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-TCLQEVIE 1733
K L Q EL++ + L + E+ + R L ++K + E++
Sbjct: 9418 AKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILR 9477
Query: 1732 QKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFK 1553
Q++ E+++E M+ KL + +++ + ++ +D
Sbjct: 9478 QRDDLEKEKEDMMKK------------WNKLDVLQNEMQNENKAMEEIKYELDGKRNEIN 9525
Query: 1552 EESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNT 1373
+E ++ + + E + L +R + + Q+ E K L+ +KS+LE T
Sbjct: 9526 KEQQRLEESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKT 9585
Query: 1372 -MDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQME 1196
+D++ + +M +K + ++ RQ +E+E
Sbjct: 9586 EIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQ------------RQQMEDE-------- 9625
Query: 1195 EYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKI 1016
++EL+ + N E K + L ++ + + D L +L E +
Sbjct: 9626 -----RSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQRNDFKLKKEELALERQN--- 9677
Query: 1015 ELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQ 836
+V++ + +++N +++ + + +K+ ++ +Q+
Sbjct: 9678 -IVDEKYLLAQCETELQNKSEQI--------------RNMEEAVKNERETLKETEAHLQR 9722
Query: 835 IEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQ 656
++ K ++ + S + D++ ++ + + ++E+ + K+ L+ + + T Q ++
Sbjct: 9723 DKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDE 9782
Query: 655 IQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDE-E 479
+ Q ++ + M+E K E++N +I K E E
Sbjct: 9783 FDAQVRKQKEE-------DLTNQKKMEE----------ERKCLEEVNGKIIEMKTKAELE 9825
Query: 478 VIKLQSQVENLQSLVQMLKQQNTKLELLAKK 386
++ ++E LQ+L + + ++ K E + K
Sbjct: 9826 HHEINQKIEELQTLQEQIMKEKEKAEAMTIK 9856
Score = 70.5 bits (171), Expect = 3e-09
Identities = 135/717 (18%), Positives = 295/717 (41%), Gaps = 94/717 (13%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKETVKNLQSD-------LDIEQKLSTDRQSEIYSLSAELERIT 2081
D R DI+ K I + L V+ + D LDIE++ D Q + A+L+
Sbjct: 11042 DLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNEN 11101
Query: 2080 QSEQMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQAN 1901
+ + + +K+ ++TL E E+ L+ E EE SV+++ + +E + ++N+ N
Sbjct: 11102 ERIKEMDEEIKKEKETLKEMEAH---LRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQN 11158
Query: 1900 EEV----KVLSKFRYQV----LELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQ 1745
+++ +L + R ++ +L++ + A +SK E+ +++ +++ + +
Sbjct: 11159 QDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETK 11218
Query: 1744 -EVIE----------QKEVEERQRECMLAASERSND-------------INVNALEKKLS 1637
++IE +KE E+ + E M A E + ++ +KKL+
Sbjct: 11219 IKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLN 11278
Query: 1636 AYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSN--------ACDLLQEIENFLREIR 1481
+ I + + D+ ++ + +EE +++ N CD IEN +EI
Sbjct: 11279 DDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCD----IEN-SKEIV 11333
Query: 1480 VETKVTIQEARHNVE--------EFSSVVKHLEYL---KSQLETSN----------TMDH 1364
+ V ++E +H ++ E + + L KS+L+ N +
Sbjct: 11334 QKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKER 11393
Query: 1363 DTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEE--- 1193
+TL ++K +S T + + E +Q+L ++ +Q E
Sbjct: 11394 ETLKEMEAYLEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEIN 11453
Query: 1192 --YKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLK 1019
+K LQ ++ + + ++ + + L M + + K ++L + +AE +K
Sbjct: 11454 HKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANIL--EMKTKAEPEEIK 11511
Query: 1018 IELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQ 839
E EK + VE +KE+ K + + Q +L I E ++
Sbjct: 11512 KE-KEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLE 11570
Query: 838 QIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFN 659
+++ Q+ + +++ Q L + +I ++KE+++ + +E +Q
Sbjct: 11571 KMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKE 11630
Query: 658 QI----------QEMLLNQNVNYPLEATVNIGFDQSMD---EAVSEIAVQTFPNKDTEDI 518
++ Q++L+ + E D+ + E + E+ V K+ E+I
Sbjct: 11631 ELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNL--QKEKEEI 11688
Query: 517 NTEIAHTSDKDEEVIKLQS----QVENLQSLVQMLKQQ----NTKLELLAKKTSEMD 371
+ I T + E++ K+ + Q ++L + +LKQ+ N KL L ++ E +
Sbjct: 11689 ESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFE 11745
Score = 70.1 bits (170), Expect = 4e-09
Identities = 138/668 (20%), Positives = 268/668 (40%), Gaps = 40/668 (5%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L +++++Q+E + + LKE +N + L +K++ + + E L A L T+ +
Sbjct: 3479 LQQMKIELQREADDIKKLKEKTRNERQSL---EKMAENLEKEKDDL-AHLAEDTKRKDDE 3534
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVL 1883
+K L E+ ++ E K LE+ +++ + I+S +K++ +L
Sbjct: 3535 MKVLHESALADIQKE------KCNLEQ----MRESMFKQNEMIDSEKKKM--------IL 3576
Query: 1882 SKFRYQVLELEEYSQQLSADLSK--VHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQ 1709
+ + Q ++ E QQ D K + + +A ++ D E+T E +E + E
Sbjct: 3577 REDKLQQMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLT 3636
Query: 1708 RECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSN 1529
+ +L + + +V L++KL E L+ D L + V K+ T
Sbjct: 3637 EKELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELL----ENEKEVLKQMKT---- 3688
Query: 1528 ACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQLETSNTMDHDTLS 1352
DL E E + +I++ET Q R VEE ++ + K EYL+ + HD
Sbjct: 3689 --DLQGEAEE-IEKIKLET----QHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKY 3741
Query: 1351 STHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-ECKSKQMEEYKMLQA 1175
Q + Q T +Q LE E E K E + Q+
Sbjct: 3742 QEKQMKQKQDELDQLKT---------------EIQNLQQELEKEKEIIMKDRSELDLKQS 3786
Query: 1174 EL-------NNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKI 1016
EL N+ + M E + M + +I K K D L ++ +K+
Sbjct: 3787 ELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKL 3846
Query: 1015 E---LVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSE- 848
+ E+ + +++E E+ K+ + ELK S L+E
Sbjct: 3847 QKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESFTHLAED 3906
Query: 847 --KIQQIEEREKV----LLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEAS 686
K Q+I + KV L+ +L + ++ + + ++ E++ + KE L+ D +
Sbjct: 3907 TKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLREDELGQL 3966
Query: 685 DTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQ-----SMDEAVSEIAV--QTFPNKD- 530
+ +I++ N+ A + I D S+D + + + F N+
Sbjct: 3967 QAEIHKQQREIEKE--KSNIESERAAIIKIVEDLQHKIISLDRDAESLKLDREAFENERE 4024
Query: 529 -TEDINTEIAHTSDKDEEVIKLQSQVEN----------LQSLVQMLKQQNTKLELLAKKT 383
+ + TE+ +D+ E+ IKL++Q E ++++ KQ N E + ++
Sbjct: 4025 VLKQMKTELERETDEIEK-IKLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQEQK 4083
Query: 382 SEMDPEKY 359
EM+ E++
Sbjct: 4084 QEMEKERH 4091
Score = 67.4 bits (163), Expect = 3e-08
Identities = 132/650 (20%), Positives = 266/650 (40%), Gaps = 34/650 (5%)
Frame = -2
Query: 2224 DIQKEK-NISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
+I EK NI + ++ Q+ + +K S D + ++ + E E + + K ++
Sbjct: 6203 EIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVE 6262
Query: 2047 EAEQTLLEAESERESLKAE---LEESISVLKQELSSARLQIESLEK-ELNQANEEVKVLS 1880
+ +Q L+ E + ESLK + E +KQ + ++Q + +EK +L +E +V
Sbjct: 6263 DLQQKLMSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRV-- 6320
Query: 1879 KFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-TCLQEVIEQKEVEERQRE 1703
++ +A + K E+ + + ++ K++ I E+ ++KE E R
Sbjct: 6321 -------------EEKTAQIQKEREEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRS 6367
Query: 1702 CMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNAC 1523
+ A ++ N N +E L+ + K LE +S + S K E
Sbjct: 6368 DLEKAKSQTFKQNKN-IEIALAEIQQKRNALEK------MSKEISRDRMKLE-------- 6412
Query: 1522 DLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTH 1343
+ K IQ AR +E ++ + K L S D L +
Sbjct: 6413 ---------------DEKKEIQLAREELERMHGDMQRQQEAKDHL-LSGITDESLLKKSE 6456
Query: 1342 -----QGSMEDKA----SSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEEC-------- 1214
Q S DKA ++ S D P +++ E+E+
Sbjct: 6457 AEIVLQPSQVDKAKPARKTEISDSDKQPVFVQQMPEMDLKDALKKDFESEKLDLPKVKDV 6516
Query: 1213 --KSKQME-EYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQL 1043
+ +QM+ E K+++ E++ L M AE+ K E D ++ K+ + N Q
Sbjct: 6517 LPQDQQMKLEQKLIEDEMDK-LKQMRAELQK-----------EADQIEKKKQDMQNERQK 6564
Query: 1042 RAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLE---LKHAN 872
+M++ E N E + +E+ I K + + Q+ AFQ+E +
Sbjct: 6565 LDDMAARLQEERRTN----------ERLNEEINIQK---VNQQKQATAFQMEKTDFERIK 6611
Query: 871 MSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNME 692
I ++++ +E+ K +T++ + ++ + A ++ E I++ + L
Sbjct: 6612 TEIDQANKELADQQEKNKKTITEMQKERETLEEMRANISKQVETITNENKSL-------- 6663
Query: 691 ASDTNLQSHFNQIQEMLLNQNVNY-PLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDI- 518
++ +S ++QE +L Q L+ T+ + Q +D+ S+I + K+ +D+
Sbjct: 6664 ---SSRESELAKLQEDILQQQQEMDELKNTIMMEMCQ-LDQRQSDIDLL---QKEVDDLM 6716
Query: 517 ---NTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSE 377
TE+A+ + E +++ +Q N++S + LK + E L K +E
Sbjct: 6717 DFTKTEMANV---ERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNE 6763
Score = 67.0 bits (162), Expect = 3e-08
Identities = 116/631 (18%), Positives = 263/631 (41%), Gaps = 25/631 (3%)
Frame = -2
Query: 2188 KETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTLLEAESER 2009
+E + +++++DIE+ + + ELE+I Q +AE E
Sbjct: 12521 REELAKMKTEIDIERDEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQHDEIHGGI 12580
Query: 2008 ESLKAELEESISVLKQELSSARLQIESLEKELNQANEEV-KVLSKFRYQVLELE--EYSQ 1838
+SLK E EE I +K +L + + E++ + + +E+ K ++ +E E + +
Sbjct: 12581 DSLKEEREE-IEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDK 12639
Query: 1837 QLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVN 1658
L ++ K+ A L+ +KN + + E + +E E + C + E++ ++N
Sbjct: 12640 NLQDEMMKI----EAILKVTKKQKNYLEQMNENL-TREKTELETNCQMLEREKT-ELNKK 12693
Query: 1657 ALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRV 1478
E + + K+ E + + +D A EE K+ +E+ N EI+
Sbjct: 12694 VKETE-EFHMSKMEEREAERKTIERVMDEMA----EEHEKIKKE---REELVNMEEEIKK 12745
Query: 1477 ETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTG 1298
+ +V ++ E + L++ +S+L D ++S + ++ + S Q
Sbjct: 12746 QRRV----LEESMNEMTKKKSELQHERSELYKQKQQLEDMIASESKRDVDTERSRQDKED 12801
Query: 1297 DNDPKAXXXXXXXXXXXECRQNLENEECK---SKQMEEYKMLQAELNNWLSCMNAEMGKF 1127
+ K ++ + E K +++ E + +Q++LN+ M+ E K
Sbjct: 12802 EQILKREREEIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKL 12861
Query: 1126 LCL-------CNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDV 968
L + N++ + D+ K +E++ Q + E I + E +A ++
Sbjct: 12862 LYMKTEIQVKTNALEKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEI 12921
Query: 967 ENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKD 788
+ +++ K R + Q ELK + SE+++ + ++++ + TK+
Sbjct: 12922 QRQFEDIESVKVRLVTESNQIDKMNSELK-------TRSEELENLIKKQQ---KEFETKE 12971
Query: 787 TDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEM--LLNQNVNYPL 614
+MQ L E+ LK+ I+ + + +LQ N+ +E+ +L + +
Sbjct: 12972 NEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREKSELY 13031
Query: 613 EATVNIGFDQSMDEAVSEIA------VQTFPNKDTEDINTEIAHTSDKDEEVIKL----Q 464
+ + + E + + ++ N+ ++ + ++ S + E+ KL Q
Sbjct: 13032 QEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTEIQ 13091
Query: 463 SQVENLQSLVQMLKQQNTKLELLAKKTSEMD 371
S+ E+++ + LKQ + E K +++D
Sbjct: 13092 SEKESIEEEKKTLKQLKDENE---SKRTQLD 13119
Score = 65.9 bits (159), Expect = 7e-08
Identities = 135/678 (19%), Positives = 282/678 (41%), Gaps = 63/678 (9%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKE-------TVKNLQSDLDIEQKLSTDRQSEIYSLSAELERIT 2081
D + I KEK S ++E T + + +++ E++ RQ E+ E+ERI
Sbjct: 546 DVEKAKILKEKEESIRIREEARQERETTELVNAEIKAEKERLNQRQEEMLRERQEIERIK 605
Query: 2080 QSEQMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQAN 1901
+ + ++ ++ + + E +KAE++ I +++++ + E +E+ +
Sbjct: 606 HETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKEQMEEAKVELE 665
Query: 1900 EEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITC---------- 1751
EE + L + R V E ++ L ++ +V E+ + R+ ++ E+
Sbjct: 666 EEREDLERKRDLVSREIEQAEFLRNEILRVKEEMESRWRETETEEVELRAKTQHELERLE 725
Query: 1750 -LQEVIE--QKEVEERQRECML-------AASERSNDINVNALEKKLSAYEGKIRRLEND 1601
L+E E QK +EE + E ML E D +V ++ ++ + K +L
Sbjct: 726 KLREETERSQKNIEESKIELMLWKESLDKLKGEMEEDKHVVIMQ--MNEAKAKEEQLTMV 783
Query: 1600 VSQLTL---SVDFSAGVFKEESTKVSNACDLLQ----EIENFLREIRVETKVTIQEARHN 1442
+ QL + + S KEE +++ + LQ E+E++ R + E K A+
Sbjct: 784 IEQLEIERGEITISREKVKEELDEINRMRNELQRQHAEMEDWFRVVNKE-KEEANLAKLA 842
Query: 1441 VEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXX 1262
V E + LK Q+E S ++ ++ ++E + Q KA
Sbjct: 843 VHEAEML------LKKQMEESEKRRYEMITE----ALEQRDEIQK-------KAEELEQI 885
Query: 1261 XXXXXECRQNLE-----NEECKSKQME---EYKMLQAELNNWLSCMNAEMGKFLCLCNS- 1109
RQ LE +E K +E + ++ ++ + L A+ K L +S
Sbjct: 886 NKEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLFEMDSE 945
Query: 1108 ---MVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLI- 941
+ + + K+DL Q R EM VE++ + ++E ++ +L+I
Sbjct: 946 RKELEQMRFQVENEKKDL----EQRRYEMMRYD---VEQSAQVQRQKEELEKIKSQLVID 998
Query: 940 ----WKDRAMIAEGQSKAFQL--ELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDM 779
+ R + + + KA L E++ + E+ +Q EE ++L + + D+
Sbjct: 999 TESMNRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRLLRKDMENEREDL 1058
Query: 778 QHLAAQLTL--------AQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVN 623
+ + + TL +EEI+ + ++ D E D + N +E ++ +
Sbjct: 1059 EKIRVE-TLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRK--- 1114
Query: 622 YPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIK--LQSQVEN 449
+EA + M E + ++ V+ K+ D+ E A + E++K L Q E+
Sbjct: 1115 --MEA-----MKREMGE-IEDMKVELTKQKENIDMKMEHARLEMTNLEMMKADLLRQKED 1166
Query: 448 LQSLVQMLKQQNTKLELL 395
+++ + K + ++E++
Sbjct: 1167 IENQMLAAKSERQQMEVM 1184
Score = 65.5 bits (158), Expect = 1e-07
Identities = 142/774 (18%), Positives = 319/774 (41%), Gaps = 66/774 (8%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
+++ ++ + ED K ++N++ +L E + ++ +E + + + L++
Sbjct: 1805 NLEAQRKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEK 1864
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQ 1865
+ + ++ER +LE + + L+ + + + LEK +++ N + K +
Sbjct: 1865 KRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEK-ISELNSQQKDEIENEKS 1923
Query: 1864 VLELEEYS-QQLSADLSKVHEDYSAALRQLFDKKNEITCLQ-EVIEQ-KEVEERQRECML 1694
+++ EY QQ+ DL++ ++ +F +K+E+ Q E+ EQ K+V + +
Sbjct: 1924 KIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQDEIAEQLKQVGDMMQ---F 1980
Query: 1693 AASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLL 1514
+E+ N L+++ +A + ++E D++ L S + K+E V N LL
Sbjct: 1981 TQNEKDN------LDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKE---VLNEKRLL 2031
Query: 1513 QEIE-NFLREIR--VETKVTIQEARHNVE-EFSSVVKHLEYLKSQLET----SNTMDHDT 1358
++ + +R+++ + K+ ++ + ++ + S+ + + L+S L+T + + DT
Sbjct: 2032 EDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDT 2091
Query: 1357 LSSTHQGSMEDKA---------------SSQSSTGDNDPKAXXXXXXXXXXXECRQNLEN 1223
L+ + +ED A ++ D D + + +L+
Sbjct: 2092 LAEKQK--LEDAAVELQKERDEIMNIAEETKRKREDVDKIRVGIEKQEITFKDLKADLQK 2149
Query: 1222 E--------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKED 1067
E + K ++ K ++ ++ M+ + + ++ ++ ++ K +++
Sbjct: 2150 EAAIVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVDKERQE 2209
Query: 1066 LLLNHGQLRAEMSSLKIE------LVEKNGFMGYAV--------LDVENVQKELLIWKDR 929
+ +L E S L+ + EKN + + L EN+ KE I
Sbjct: 2210 VESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTI---- 2265
Query: 928 AMIAEGQSKAFQLELKHANMSICSLSEKIQQIEE------REKVLLTQLSTKDTDMQHLA 767
F+LE +H + K +QI+E EKV + Q+ D D Q
Sbjct: 2266 ----------FELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQA-DKDQQRKK 2314
Query: 766 AQL--------TLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLE 611
A+ T A EE E L++ +N+E + H N+ +E+ ++ + +E
Sbjct: 2315 AEYVKTARGRETTALEEQRQEMESLREEYENVEKQ----KKHVNEQKELFESRMKSLEME 2370
Query: 610 ATVNIGFDQSMDEAVSEIAVQ-TFPNKDTEDINTEIAHTSDKDEEVIK-LQSQVENLQSL 437
+ + +D+ ++ Q K+ + + TE+ ++ E K L+ Q + +
Sbjct: 2371 NEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTE 2430
Query: 436 VQMLKQQNTKLELLAKKTSEMDPEKYFHFEELCQSLVXXXXXXXXXXXXXXXKNQVLVKQ 257
ML+ Q +E KT E+D + +L S V + + VK+
Sbjct: 2431 TYMLETQKPVVE--KSKTDELDEVRKKINADL--SEVEKQKSALVQMNLKISQEESYVKK 2486
Query: 256 VKEMQVTLQSESPMEGETDSISENAIGSQPA--GKLSTELHNVHGNTERVPLQL 101
K+ ++E M+ + +N + + A K EL NV E+ +++
Sbjct: 2487 EKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEI 2540
Score = 65.5 bits (158), Expect = 1e-07
Identities = 135/673 (20%), Positives = 272/673 (40%), Gaps = 57/673 (8%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQ--------KLSTDR---QSEIYSLSAELERITQ 2078
D+QKEKN +E+LK ++ +S+L E+ ++ T R +SE+ +L +
Sbjct: 13008 DLQKEKNKTEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELED 13067
Query: 2077 SEQMSLKRLK----EAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELN 1910
++ L RL E ++ E +SE+ES++ E ++++ LK E S R Q+++ +++N
Sbjct: 13068 EKKSMLSRLSMEKHEIDKLKTEIQSEKESIEEE-KKTLKQLKDENESKRTQLDNTIEKMN 13126
Query: 1909 ----------QANEEVKVLSKFRYQVLELE-----EYSQQLSADLSKVHED--------- 1802
+ EE+K + + + L+ E + + Q+S D + +D
Sbjct: 13127 MDKLSIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRS 13186
Query: 1801 -YSAALRQLFDKKNEITCLQ---EVIEQKEVEERQRECMLAASERSNDINVNALEKKLSA 1634
+ RQ ++++ LQ E++E+ + E L + ND+ + L K+ A
Sbjct: 13187 MRADIERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEKQRKRNDLTLQELRKEKMA 13246
Query: 1633 YEGKIRRLEND---VSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVT 1463
E I + + V+ L V K + T++ + ++ L + T
Sbjct: 13247 LEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQ 13306
Query: 1462 IQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPK 1283
QE + E + LE +K+ L+ D + + S + D
Sbjct: 13307 QQEVDVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDEL 13366
Query: 1282 AXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMV 1103
+ E + +K++ + K LN + E+ S+
Sbjct: 13367 EKFTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLE 13426
Query: 1102 YLEGDILKYKED---LLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWK- 935
L D+L +D L+ Q+ E + K E VE + ++E ++ + K
Sbjct: 13427 QLRADLLAGADDIKTLVQTEKQMAIEDTEKKTE-VELQMNLQKQKNELEELRNTIEAEKH 13485
Query: 934 ---DRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAA 764
+R ++ + Q K + I ++ + + + E+EK L +LS L
Sbjct: 13486 QVENRKIMLDKQQKEVE--------DIMTVIKSERDVLEKEKSELNKLS------HVLNE 13531
Query: 763 QLTLAQEEISSTKEMLKDFIDN----MEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNI 596
++ QEE+ E +D I+N +E+ +++ +++ L + V E T+ +
Sbjct: 13532 KVQREQEELERLLEKERDDIENCKKIIESEKQSIERERAELKR--LKEEVEVQHERTL-L 13588
Query: 595 GFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQ 416
D++M + K+ E + E A T+ EE+ L+ +++ S + ML +
Sbjct: 13589 QQDKNMIQ------------KEKEHLEGEKARTT---EEIHNLKEEIKRKSSELDMLNK- 13632
Query: 415 NTKLELLAKKTSE 377
E+ AK+ E
Sbjct: 13633 ----EIEAKRQEE 13641
Score = 64.7 bits (156), Expect = 2e-07
Identities = 117/652 (17%), Positives = 266/652 (40%), Gaps = 26/652 (3%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L+ + D+QK K +E + L+ + QSE+ SL+ E++ + Q +
Sbjct: 13950 LNKAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIK--- 14006
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVL---KQELSSARLQIESLEKELNQANEEV 1892
E +Q ++ + + S+ + E + + ++ + + + E+E++ +
Sbjct: 14007 ----TEMQQIEIKMQIQTRSVATQWETDVQIQQEGQEPIETTGHITKKSEEEISAKKTKQ 14062
Query: 1891 KVLSKFRYQVL-ELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVE- 1718
+++K + E++E D++++ QL K++I E E+ E
Sbjct: 14063 PIVTKLEDTLTSEVQEMRDMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEET 14122
Query: 1717 ----ERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
R E +L +D++ N L++K E + +++QL ++ + K+
Sbjct: 14123 LKEKSRNEETLLQLLHDKDDLS-NTLDEKSKEIENITVTFKRNIAQLETTI----AMMKK 14177
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTM 1370
+ + N L++ E REI+ T T E E + V + L+ E
Sbjct: 14178 DKENIENELLQLKQTEQ-EREIQRGTDDTSNER----ENYDEKVTYKTELEDSKEKKKPD 14232
Query: 1369 DHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-ECKSKQMEE 1193
+L T S + ++ T + K + ++ L +E E K K + E
Sbjct: 14233 RDSSLKLTDADSAKTDGEREAQT--LETKVQDVLQLTDYTTQDQEELHDEMENKMKIILE 14290
Query: 1192 YKMLQAELNNWL-SCMNAEMGKFLCL------CNSMVYLEGDILKYKEDLLLNH-GQLRA 1037
+ +L C +AE K + + NS+ ++ ++L ++ ++H Q++
Sbjct: 14291 LNEAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQE--IDHLAQIKT 14348
Query: 1036 EMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICS 857
EM ++I++ + +V + W+ I +GQ E I
Sbjct: 14349 EMQQIEIKM----------QIQTRSVATQ---WETDVQIQQGQ------EATETTGHITK 14389
Query: 856 LSEKIQQIEEREKVLLTQL-STKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDT 680
SE+ ++ ++ +T+L T +++Q + L E+++ K ++K D +E + +
Sbjct: 14390 KSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVARMKTIMKMEKDQLEQAKS 14449
Query: 679 NLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAH 500
++Q+ + F+++M+EA+ E + ++++
Sbjct: 14450 DIQTQMEE---------------------FERNMEEAMEEKSRNEEKLLQLTHDKEDLSN 14488
Query: 499 TSDKDEEVIKLQSQ-----VENLQSLVQMLK--QQNTKLELLAKKTSEMDPE 365
T DK + I+ ++ + L++ + ++K ++N + ELL K +E + E
Sbjct: 14489 TLDKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQERE 14540
Score = 63.9 bits (154), Expect = 3e-07
Identities = 125/676 (18%), Positives = 275/676 (40%), Gaps = 49/676 (7%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDL-------KETVKNLQSDLDIEQKLSTDRQSEIYSL-SAELER 2087
++ + D+Q E+ +D+ + T + L +++I QK++ +Q+ + + + ER
Sbjct: 6551 IEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINI-QKVNQQKQATAFQMEKTDFER 6609
Query: 2086 ITQSEQMSLKRLKEAEQ----TLLEAESERESLKAELEESISVLKQELSSARLQIESLEK 1919
I + K L + ++ T+ E + ERE+L+ E+ +IS + +++ + S E
Sbjct: 6610 IKTEIDQANKELADQQEKNKKTITEMQKERETLE-EMRANISKQVETITNENKSLSSRES 6668
Query: 1918 ELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEV 1739
EL + E++ Q E++E + ++ QL ++++I LQ+
Sbjct: 6669 ELAKLQEDI------LQQQQEMDELKNTIMMEMC-----------QLDQRQSDIDLLQKE 6711
Query: 1738 I---------EQKEVEERQRECMLAASERSNDINVNALEK------KLSAYEGKIRRLEN 1604
+ E VE + E + +D+ +EK +L E K +E
Sbjct: 6712 VDDLMDFTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNEEK-DLIEK 6770
Query: 1603 DVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS 1424
+ LT ++D + + ++ N + I+N +E+ + K+++Q +EFS
Sbjct: 6771 ERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKELE-KMKISLQRKAIGFKEFSE 6829
Query: 1423 VVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXE 1244
K + ++ T D +G ++ Q+ + K E
Sbjct: 6830 KTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQT-----EKKRRKTYYTEDLFQE 6884
Query: 1243 CRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL 1064
+ +L+ K EE + E+ + +N E + S + +I K KE +
Sbjct: 6885 EKTDLQ------KTKEEINYDREEIYRQRTELNKEKETLKQMHTSNLKEIENIEKEKEKI 6938
Query: 1063 LLNHG---QLRAEMSSLKIELVEKNGFM----GYAVLDVENVQKELLIWKDRAMIAEGQS 905
Q+RAE+ + + ++ + M D+EN+Q E KD +
Sbjct: 6939 QRTWNELDQIRAELQNKQRDMDDTTNIMMKEKAELARDLENLQNE----KDELQKSRENI 6994
Query: 904 KAFQLELKHANMSIC-SLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISST 728
+ EL+ + +L+++ QQ E ++ K+ + + A++ + + +
Sbjct: 6995 QKLMKELQEERLKTSEALNKERQQFTE-------EIKLKNDSLDEIQAEIDRQKRALVTD 7047
Query: 727 KEML-KDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNI-----GFDQSMDEAV 566
KE++ K +D + D QS + I L + + +V I ++ DE +
Sbjct: 7048 KEIITKQMMDLQKTQDVRRQSDESDIARANLQRERESLDQLSVEILKQKQDLERERDELL 7107
Query: 565 SE---IAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQ-----VENLQSLVQMLKQQNT 410
+ + Q N++ + + TE+ + E++ K Q EN +L + L++ N
Sbjct: 7108 EQWRLVETQKMDNENVKQLKTELLDEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNL 7167
Query: 409 KLELLAKKTSEMDPEK 362
+ + + + ++++ K
Sbjct: 7168 QKQGIQDERAQLERMK 7183
Score = 63.9 bits (154), Expect = 3e-07
Identities = 130/706 (18%), Positives = 276/706 (39%), Gaps = 79/706 (11%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLD--------IEQKLSTDR------------- 2126
++ +R DI +EKN ++ +SDL+ +Q + +R
Sbjct: 12237 IEKIRQDIDREKN-------DLEKYRSDLEKQYEEMEICKQNIENERAELEIDLENIIIE 12289
Query: 2125 ----QSEIYSLSAELE---------------RITQSEQMSLKRLKEAEQTLLEAESERES 2003
Q + S+ +L+ R + + + K +E EQ E E++
Sbjct: 12290 TKSKQERLESIEVQLQEKNVQMGTILDELNKRQEELDAIKAKTQREKEQMGHTEELEKDE 12349
Query: 2002 LKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSAD 1823
L A L++ ++K+ + + Q E L+KE +Q L K + LE+E + L+++
Sbjct: 12350 LIAILQKREEIVKRHMEEIQNQREELQKEKDQFGNMQAELQKGQ---LEMEMHQLMLNSE 12406
Query: 1822 ----------LSKVHEDYSAALRQLFDKKNEITCLQEVI-EQKEVEERQRECMLAASERS 1676
L K E++ + L ++ E + L++++ E+K VEE M A +
Sbjct: 12407 RDELNGMRVNLEKQKEEFELMQQNLESRRPE-SLLEDILKEKKRVEE-----MAAQLSKE 12460
Query: 1675 NDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDL----LQE 1508
+ N + + + E KI+++E ++ + + + ++E + N + LQ
Sbjct: 12461 QEEFRNIMSETIKRME-KIKQIEGEIKTKQIEMACLEELKQKELDEQKNMRECENQELQM 12519
Query: 1507 IENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSN------TMDHDTLSST 1346
L +++ E + E + +++ LE +K L+ + HD +
Sbjct: 12520 RREELAKMKTEIDIERDEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQHDEIHGG 12579
Query: 1345 HQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELN 1166
E++ + D K + LE +E + +QM ++ E N
Sbjct: 12580 IDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQM----AVETEDN 12635
Query: 1165 NWLSCMNAEMGKFLCLC-------NSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELV 1007
+ + EM K + N + + ++ + K +L N L E + L ++
Sbjct: 12636 DSDKNLQDEMMKIEAILKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNKKVK 12695
Query: 1006 EKNGFMGYAVLDVENVQKELLIWKDRAM--IAEGQSKAFQLELKHANMSICSLSEKIQQI 833
E F + + E +K + +R M +AE K +K + ++ E+I++
Sbjct: 12696 ETEEFHMSKMEEREAERKTI----ERVMDEMAEEHEK-----IKKEREELVNMEEEIKKQ 12746
Query: 832 EEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQ-SHFNQ 656
+ + +++ K +++QH + E+ K+ L+D I + D + + S ++
Sbjct: 12747 RRVLEESMNEMTKKKSELQH-------ERSELYKQKQQLEDMIASESKRDVDTERSRQDK 12799
Query: 655 IQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEV 476
E +L + E ++++ Q K+ ED+ T + + E +
Sbjct: 12800 EDEQILKRE-----------------REEIADMKDQLL--KEKEDVETTKERINREKEHI 12840
Query: 475 IKLQSQVENL--------QSLVQMLKQQNTKLELLAKKTSEMDPEK 362
K+QSQ+ + Q L+ M + K L K ++ E+
Sbjct: 12841 EKMQSQLNDQKEEMDLENQKLLYMKTEIQVKTNALEKMMQDLQKER 12886
Score = 63.5 bits (153), Expect = 4e-07
Identities = 110/654 (16%), Positives = 277/654 (42%), Gaps = 44/654 (6%)
Frame = -2
Query: 2230 RLDIQKEKNISEDL-------KETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSE 2072
+ DI+ K I + L K ++ + +LDIE++ D Q + +EL+ +
Sbjct: 10209 KCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERI 10268
Query: 2071 QMSLKRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKEL-NQA 1904
+ + +K+ +TL E E+ E K E++ E LK++L + K+L NQ
Sbjct: 10269 RNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRLKEDLEKMSTDVNKQNKDLMNQR 10328
Query: 1903 N----EEVKVLSKFRYQVLELEEYSQQLS----ADLSKVHEDYSAALRQLFDKKNEITCL 1748
+ E ++ K++ ++E+ Q+S DL K + + L + K + +
Sbjct: 10329 DLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPK-EKGMKEDRKSLEETKANVIEM 10387
Query: 1747 QEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFS 1568
+ E +E+++ + + E +I V ++ Y+ +++++ ++ +D
Sbjct: 10388 KTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELYQ-----IKSELERVRSEID-- 10440
Query: 1567 AGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQL 1388
E K+++ ++++ + L +++ E Q+ E + ++ K +
Sbjct: 10441 -----HEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDI 10495
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKS 1208
E S + + E + Q + D + + + L+NE +
Sbjct: 10496 EKSKEIVEKLMVEVE----EQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERI 10551
Query: 1207 KQM-EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEM 1031
K++ EE K + L + E + + + D+ K D+ L+ +
Sbjct: 10552 KKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQR 10611
Query: 1030 SSLKIELVEKNGFMGYAVLDVE------NVQKELL----IWKDRAMIAEGQSKAFQLELK 881
L+ E E N M ++ + Q+E L + ++R + E +++ +++ K
Sbjct: 10612 DLLEQEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTK 10671
Query: 880 HANMSICSLSEKIQQIEEREKVLL----TQLSTKDTDMQHLAAQLTLAQEEISSTKEMLK 713
I + EK ++ EE +V++ +L+ ++++ + +++ Q++++ K++++
Sbjct: 10672 AELQEI--MQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIE 10729
Query: 712 DFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFD-QSMDEAVSEIAVQTFPN 536
+++E + + + Q++E ++ ++ T D ++ E V ++ V+
Sbjct: 10730 QEKEDLEKMKSEIMTQRQQMEEE--RSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQ 10787
Query: 535 K-----DTEDINTEIAHTSDKDEEVI----KLQSQVENLQSLVQMLKQQNTKLE 401
+ E+++ E +D+ V+ KLQ++ E ++ + + +K++ L+
Sbjct: 10788 RKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLK 10841
>ref|XP_005159742.1| PREDICTED: titin isoform X5 [Danio rerio]
Length = 15134
Score = 102 bits (253), Expect = 9e-19
Identities = 127/657 (19%), Positives = 292/657 (44%), Gaps = 30/657 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD + ++ K++ D+ ET+KN + LD +++ +++ E+ +++ +S
Sbjct: 5748 LDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDED 5807
Query: 2062 LKRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQANEEV 1892
LK +K +Q + E +++ E +K ELE + I +K+E + R +E + +EL + ++V
Sbjct: 5808 LKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDV 5867
Query: 1891 KVLS----KFRYQVLELEEYSQQLSADLSK-------VHEDYSAALRQLFDKKNEITCLQ 1745
L+ + + + E++ ++ ADL K + E+ S + +K++I +
Sbjct: 5868 AHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLRE 5927
Query: 1744 EVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSA 1565
+ +EQ + E +++ + + + A+ K + + KI L+ D L L +
Sbjct: 5928 DELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDRE--- 5984
Query: 1564 GVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQL 1388
F+ E ++ L+ + + +I++ET Q R VEE ++ ++ + + QL
Sbjct: 5985 -AFENEKEELKQMKTELEREADEIEKIKLET----QHERQRVEEMTADFMETMNNERKQL 6039
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKS 1208
+ + M E K + D D +Q LE E+ K
Sbjct: 6040 DKNKVMIE-----------EQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKL 6088
Query: 1207 KQM--------EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL---- 1064
+QM +E ++ E N + L YL +I + + L
Sbjct: 6089 EQMKIGLEREADEISKIKEETQNERQNLEKMAN---ALKEEREYLAEEIKRKNQVLDKIK 6145
Query: 1063 LLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKD--RAMIAEGQSKAFQL 890
+ N L A++ K L E + + D+EN +++ + +D + + E Q + ++
Sbjct: 6146 VANESTL-ADLQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEI 6204
Query: 889 ELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKD 710
+++ N+ SE+ I E++ ++T+L K D++ ++ +E + + + +LK
Sbjct: 6205 DMEKTNIE----SERAAMIREKQN-MMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKK 6259
Query: 709 FIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKD 530
+++++ +++ ++++ EA N ++M + +++ +Q +
Sbjct: 6260 DVEDLQQKLMSIERD---------SESLKLDKEAFEN--EKEAMKQMKTDLQIQA---DE 6305
Query: 529 TEDINTEIAHTSDK-DEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEK 362
E I E H + +E+ ++Q + E + +LV+ +K+ K +++ + +E+ EK
Sbjct: 6306 IEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIKK---KRDIIDESYTEIRKEK 6359
Score = 100 bits (250), Expect = 2e-18
Identities = 128/638 (20%), Positives = 274/638 (42%), Gaps = 31/638 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD + ++ K++ D+ ET+KN + LD +++ + +++ E+ + ++ +S
Sbjct: 4461 LDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 4520
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEE---SISVLKQELSSARLQIESLEKELNQANEEV 1892
LK +K +Q L + +S+ E +K ELE I +K+E+ + R +E + + L + E++
Sbjct: 4521 LKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL 4580
Query: 1891 KVLSKFRYQVL-ELEEYSQQLSAD-------LSKVHEDYSAALRQLFDKKNEITCLQEVI 1736
+K QVL E++ ++ AD L ++ E+ S + +KK + ++ +
Sbjct: 4581 AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDEL 4640
Query: 1735 EQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTL---SVDFSA 1565
Q + E +++ + + + + A+ K + + KI L+ D L L + +
Sbjct: 4641 RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEK 4700
Query: 1564 GVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQL 1388
V K+ T++ D +++I K+ Q R VEE ++ + K + + + +
Sbjct: 4701 EVLKQMKTELEREADEIEKI-----------KLETQHDRQRVEEMAAQIQKDRDEINNLI 4749
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE---- 1220
E +N D L+ ++ E S QS + + + +++LE +
Sbjct: 4750 EETNRKDM-VLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENT 4808
Query: 1219 --------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL 1064
E K E E+ + MN + + L + L+ ++ K KE +
Sbjct: 4809 LAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEII 4868
Query: 1063 LLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLEL 884
+ + QL S L + N M ++N +K+L KD+ + E Q + + E
Sbjct: 4869 MKDRSQLDLRQSELDKQQTNMNDIME----TMKNERKQL--DKDKEEMEE-QKQEMEKER 4921
Query: 883 KHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFI 704
+ + S SL E +++ K+ + ++ + +L +EIS KE ++
Sbjct: 4922 DNMDQSRKSLDED----QKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKR 4977
Query: 703 DNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAV----QTFPN 536
+E L + + + + + + + SM + E ++ + +
Sbjct: 4978 QRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENIS 5037
Query: 535 KDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
K E I+ E + +++E+ KLQ++V+ QS + M K
Sbjct: 5038 KLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEK 5075
Score = 95.1 bits (235), Expect = 1e-16
Identities = 127/646 (19%), Positives = 274/646 (42%), Gaps = 26/646 (4%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
D+Q+EK+I E+++E + L+ +D E++ S R+ E+ L E++ K+ +
Sbjct: 5021 DLQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQ----------KQQSK 5070
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSK---- 1877
+ ESER ++ E + ++ LK++ +Q++ + E + + K+L++
Sbjct: 5071 IDMEKTNIESERAAMIREKQNMMTELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVEN 5130
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVE---ERQR 1706
+ ++++LE S++L D + E+ A++Q+ K ++ + IE+ ++E +RQR
Sbjct: 5131 LQQKLIDLERDSKRLKLD-REAFENEKEAMKQM---KTDLQIQADEIEKIKLETQHDRQR 5186
Query: 1705 ECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNA 1526
+AA + +N L ++ + + + D+ + S+ + ++E +
Sbjct: 5187 VEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKT 5246
Query: 1525 CDLLQEIENFLREIRVETKVTIQEARHNVEEFS-SVVKHLEYLKSQLETSNTMDHDTLSS 1349
L +++ L + + T IQ+ R +VE+ + ++ + + +K Q E N
Sbjct: 5247 RSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMN--------- 5297
Query: 1348 THQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-ECKSKQMEEYKMLQAE 1172
+D+ + N +Q LE E E K ++ + Q+E
Sbjct: 5298 ----QKQDELDQLKTEIQN----------------LQQELEKEKEIIMKDRSQFDLRQSE 5337
Query: 1171 L-------NNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIE 1013
L N+ + M E + M + ++ K K D + L ++ +K++
Sbjct: 5338 LDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKDLKMMKLQ 5397
Query: 1012 ---LVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSE-- 848
E+ + +++E E+ K+ + ELK S L+E
Sbjct: 5398 KQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFTHLAEDT 5457
Query: 847 -KIQQIEEREKV----LLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASD 683
K Q+I ++ KV L+ L + ++++ + ++ E++ + KE L+ D +
Sbjct: 5458 KKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLREDEL---- 5513
Query: 682 TNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIA 503
LQ+ + Q + + +N E I K+ ED+ +I
Sbjct: 5514 WQLQAEIYKQQREIEKEKINIESERAAII--------------------KNVEDLQHKII 5553
Query: 502 HTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPE 365
+ D+D E +KL E ++ ++LKQ T+LE A + ++ E
Sbjct: 5554 -SLDRDSESLKLDR--EAFENEREVLKQMKTELEREADEIEKIKLE 5596
Score = 92.0 bits (227), Expect = 1e-15
Identities = 127/649 (19%), Positives = 278/649 (42%), Gaps = 43/649 (6%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSL 2060
D + ++ K++ D+ ET+KN + LD +++ +++ E+ + ++ +S L
Sbjct: 5332 DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKDL 5391
Query: 2059 KRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKELNQANE--- 1898
K +K +Q E +++ E +K ELE + I +K+E + R +E + +EL + E
Sbjct: 5392 KMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFT 5451
Query: 1897 --------EVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQE 1742
E ++L K + L Q+ ++L ++ E+ S + +KK + ++
Sbjct: 5452 HLAEDTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLRED 5511
Query: 1741 VIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTL---SVDF 1571
+ Q + E +++ + + + + A+ K + + KI L+ D L L + +
Sbjct: 5512 ELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFEN 5571
Query: 1570 SAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKS 1394
V K+ T++ D +++I K+ Q R VEE ++ + K + + +
Sbjct: 5572 EREVLKQMKTELEREADEIEKI-----------KLETQHDRQRVEEMTAQIQKDRDKINN 5620
Query: 1393 QLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-- 1220
+E +N D L+ ++ + S QS + + + +++LE +
Sbjct: 5621 LIEETNRKDM-VLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKE 5679
Query: 1219 ----------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKE 1070
E K E E+ + MN + + L + L+ ++ K KE
Sbjct: 5680 NTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKE 5739
Query: 1069 DLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQL 890
++ QL S L + N M ++N +K+L KD+ + E Q + +
Sbjct: 5740 IIMKARSQLDRRQSELDKQQTNMNDIME----TMKNERKQL--DKDKEEMEE-QKQEMEK 5792
Query: 889 ELKHANMSICSLSEKIQQIEEREKVL---LTQLSTKDTDMQHLAAQLTLAQEEISSTKEM 719
E + + S SL E ++ ++ +++V+ +L +++ A + +EE + +++
Sbjct: 5793 ERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQI 5852
Query: 718 LKDFIDNME---------ASDTNLQSHFNQIQEM-LLNQNVNYPLEATVNIGFDQSMDEA 569
L+ + ++ A DT + N + EM + N++ L+ +++E
Sbjct: 5853 LEKMAEELKKERKDVAHLAEDTKREK--NSLDEMKVANESSMADLQKE-----KSNLEEM 5905
Query: 568 VSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLK 422
I +K TEDI E +++E+ +LQ+++ QS ++ K
Sbjct: 5906 KENI------SKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEK 5948
Score = 90.5 bits (223), Expect = 3e-15
Identities = 133/649 (20%), Positives = 269/649 (41%), Gaps = 30/649 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD + ++ K++ D+ ET+KN + LD +++ +++ EI + ++ S
Sbjct: 3781 LDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDED 3840
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEE---SISVLKQELSSARLQIESLEKELNQANEEV 1892
LK +K +Q E +++ E +K ELE I +K+E+ + R +E + +EL + E
Sbjct: 3841 LKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESF 3900
Query: 1891 KVL---SKFRYQVL-ELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKE 1724
L +K ++L E++ ++ L A+L K ++ + + ++ +E + +E
Sbjct: 3901 THLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLRE 3960
Query: 1723 VEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEES 1544
E Q + + +R + + +E + +A I ++ D+ +S+D A K +
Sbjct: 3961 DELGQLQAEIHKQQREIEKEKSNIESERAA----IIKIVEDLQHKIISLDRDAESLKLDR 4016
Query: 1543 TKVSNACDLLQ----EIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSN 1376
N ++L+ E+E EI + K+ Q R VEE ++ +ET N
Sbjct: 4017 EAFENEREVLKQMKTELEREADEIE-KIKLETQHERQRVEEMTA---------DFMETMN 4066
Query: 1375 TMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQM- 1199
+ L+ + E K + D D +Q +E E+ K +QM
Sbjct: 4067 N-ERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMK 4125
Query: 1198 -------EEYKMLQAELNN---WLSCMNAEMGKFLCLCNSMVYLEGDI---LKYKEDLLL 1058
+E + ++ E N L M E+ K S +L D K + + +
Sbjct: 4126 IELEKEADEIRKIKEETQNERQRLEKMTEELKKEK---ESFTHLAEDTKTEKKILDKMKV 4182
Query: 1057 NHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKH 878
+ L A++ K L E + D E ++++ + +D + + Q E+K
Sbjct: 4183 ANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQLQAEIHKQQGEIK- 4241
Query: 877 ANMSICSLSEKIQQIEEREKVLLTQLSTKDT-DMQHLAAQLTLAQEEISSTKEMLKDFID 701
EK ER ++ KD D+QH L E + +E ++ +
Sbjct: 4242 --------MEKSNNESERAAII------KDVKDLQHKMFSLDRDLESLKLDREAFENERE 4287
Query: 700 NMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTED 521
++ T+L+ +I+++ L + Q ++E ++I K+ +
Sbjct: 4288 VLKQIKTDLKRKAEEIEKIKLETQHD-----------RQRVEEMTAQI------QKERDK 4330
Query: 520 INTEIAHTSDKD----EEVIKLQSQVENLQSLVQMLKQQNTKLELLAKK 386
IN I T+ KD E +++ +++ ++S ML+++ LE K
Sbjct: 4331 INNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSK 4379
Score = 84.0 bits (206), Expect = 3e-13
Identities = 137/676 (20%), Positives = 281/676 (41%), Gaps = 48/676 (7%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDL-DIEQKLSTDRQSEIYSLS-AELER---ITQ 2078
L R DI+K E K ++ + +L D + +L DR + ++ EL+R + +
Sbjct: 8602 LQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRE 8661
Query: 2077 SEQMSLKRLKEAEQTLL---EAESERESLK-------------AELEESISVLKQELSSA 1946
+E + K L++ EQ + + E++ E+L+ A+ E++ +Q+L
Sbjct: 8662 TEDLERKILQQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLL 8721
Query: 1945 RLQIESLEKELNQA--NEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFD 1772
+ ++S E EL EE K L + + + E + ++S ++ +Y + +L
Sbjct: 8722 QGALQSQESELENRVFMEEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQR 8781
Query: 1771 KKNEITCLQEVIEQKEVE--------ERQRECMLAASERSNDINVNALEKKLSA---YEG 1625
+K ++ + IEQ++ + ERQ E + D NALEK S +
Sbjct: 8782 EKEQLEISKNQIEQEKKDLQNMKSNLERQLESLRHEKANVED-EKNALEKMRSESKEIQN 8840
Query: 1624 KIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARH 1445
IR+ D+ + ++ +EE+ ++ + ++++++ L++ R + ++ +
Sbjct: 8841 AIRKEREDLENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINN 8900
Query: 1444 NVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXX 1265
+EE + + K ++E + D E + D K
Sbjct: 8901 KMEELLQMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQE--- 8957
Query: 1264 XXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDI 1085
+ E K + +E K L E+ + + EM + +G +
Sbjct: 8958 ------------KEREIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLL 9005
Query: 1084 LKYKEDLLLNHGQLRAEMSSL---KIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAE 914
K K++L +L +M L K E E+ + +E+++KE I K++ + +
Sbjct: 9006 EKEKQELKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEK 9065
Query: 913 GQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTK-DTDMQHLAAQLTLAQEE- 740
+ QL++ L+++ ++ ++EK L Q + + Q L T EE
Sbjct: 9066 SNIEEMQLKIFKQQR----LNDQTREENKKEKESLEQQRFETEQQKQMLEISTTKMMEEK 9121
Query: 739 -----ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMD 575
+S + KD ++ + A TN + H + + L+ + +E I D+
Sbjct: 9122 NEMADLSRELQKAKDELEKI-AYKTNKERHEVEQMQAELHSQIQ-AIEQQGQIMQDKQNH 9179
Query: 574 EAVSEIAVQTFPNK---DTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTK- 407
E+++Q + + E H ++ EE K Q +E +++ +++ KQ+N K
Sbjct: 9180 LEEKELSIQRKEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQKNNKD 9239
Query: 406 LELLAKKTSEMDPEKY 359
ELL K SE++ EKY
Sbjct: 9240 FELLEKIRSELENEKY 9255
Score = 81.6 bits (200), Expect = 1e-12
Identities = 127/652 (19%), Positives = 275/652 (42%), Gaps = 31/652 (4%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIE-QKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++ +K+I E+ + + DL E K S D + ++ + E E + ++ K ++
Sbjct: 3594 EMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLTEKELLESDRKLLKKDVE 3653
Query: 2047 EAEQTLLEAESERESLKAE---LEESISVLKQELSSARLQIESLEKELNQANEEVKVLSK 1877
+Q LL ES+ ESLK + LE VLKQ + + + E +EK + E + + +
Sbjct: 3654 NLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEE 3713
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIE--QKEVEERQRE 1703
Q+ + EY Q+++ ++++ D +Q+ K++E+ L+ I+ Q+E+E+ +
Sbjct: 3714 MTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQELEKEKEI 3773
Query: 1702 CMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSV---------------DFS 1568
M SE D+ + L+K+ + I ++N+ QL DF
Sbjct: 3774 IMKDRSEL--DLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFD 3831
Query: 1567 AG--VFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKS 1394
G E+ + + +E +N L ++++E + E R EE + + LE +
Sbjct: 3832 QGRNSLDEDLKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTE 3891
Query: 1393 QLETSNTMDHDTLSSTHQGSMEDKASSQSSTGD----NDPKAXXXXXXXXXXXECRQNL- 1229
+L+ + S TH ED Q + N+ E R+N+
Sbjct: 3892 ELK------REKESFTHLA--EDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENIS 3943
Query: 1228 -ENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNH 1052
+ E+ K+K+ E ++ + EL + ++ + + +++ I+K EDL
Sbjct: 3944 KQTEDVKNKK-ENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKI 4002
Query: 1051 GQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHAN 872
L + SLK+ ++ F EN ++ L K + + +LE +H
Sbjct: 4003 ISLDRDAESLKL---DREAF--------ENEREVLKQMKTELEREADEIEKIKLETQHER 4051
Query: 871 MSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNME 692
+ ++ + E+ QL+ +MQ ++ + ++ +++ L + M+
Sbjct: 4052 QRVEEMTADFMETMNNER---KQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMK 4108
Query: 691 ASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINT 512
++ N++++M + EA + + T K ++ T
Sbjct: 4109 LQKQVIEEEKNKLEQM----KIELEKEADEIRKIKEETQNERQRLEKMTEELKKEKESFT 4164
Query: 511 EIAHTSDKDEEVI-KLQSQVENLQSLVQMLKQQNTKL-ELLAKKTSEMDPEK 362
+A + +++++ K++ E+L + +Q K ++ E ++K+T + + EK
Sbjct: 4165 HLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEK 4216
Score = 79.7 bits (195), Expect = 5e-12
Identities = 122/685 (17%), Positives = 295/685 (43%), Gaps = 64/685 (9%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
+I+KEK KE + + + +I + T+R+ E+Y + +ELER+ K+L +
Sbjct: 10395 EIKKEKE-----KENEEEEEEEEEIRVIVETERK-ELYQIKSELERVRSEIDHEQKKLND 10448
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSA--RLQIESLEKELNQANEEV--KVLSK 1877
+ + + + + E +K+E+ + +++E S ++Q +LEK + ++E+ K++ +
Sbjct: 10449 YMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVE 10508
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECM 1697
Q +++ ++L + K+ ++ + ++ +NE +++V E+ +++RE +
Sbjct: 10509 VEEQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKKVDEE---IKKERETL 10565
Query: 1696 LAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDL 1517
R +I++ +++L + + +R + D+ +++ ++ E+ + N DL
Sbjct: 10566 -----REMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDIN-------EQKLHLKNQRDL 10613
Query: 1516 LQEIENFLREIRVETKVTIQEARHNVEEFSSVV--KHLEYLKSQLETSNTMDHDTLSSTH 1343
L+ + R E + + + ++EF + V + + K ++E +T +
Sbjct: 10614 LE-------QEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARII 10666
Query: 1342 QGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECK---SKQMEEYKMLQAE 1172
+ M+ KA Q + + + + EE + + EE +++E
Sbjct: 10667 E--MKTKAELQEIMQEKEEE------------------DEEEMRVIVEMEREELNQIKSE 10706
Query: 1171 LNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSL---------- 1022
L S ++ E K + + D+ K K +++ Q+ E S L
Sbjct: 10707 LKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLE 10766
Query: 1021 KIELVEKNGFMGYAVLDVENVQKELLIWK-----DRAMIAEGQSKAFQ--LELKHANMSI 863
+ ++ + ++ VE +K++ + K +R IA+ Q Q +L++ N I
Sbjct: 10767 RHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERI 10826
Query: 862 CSLSEKI---------------QQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISST 728
+ E+I ++ EE V+ K D++ ++ + +++ +
Sbjct: 10827 KEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDVNKQNQDLMNQ 10886
Query: 727 KEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEA---VSEI 557
+++LK + + T LQ ++ + Q + +S++E + E+
Sbjct: 10887 RDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEM 10946
Query: 556 AVQTFP-----NKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLV-----------QML 425
+T P K+ E+ A K EE+ +++SQ+E ++S + +M+
Sbjct: 10947 KTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMI 11006
Query: 424 KQQNTKLEL----LAKKTSEMDPEK 362
+Q+ LE + K+ +M+ E+
Sbjct: 11007 EQEKEDLEKMKSEIMKQRQQMEEER 11031
Score = 78.6 bits (192), Expect = 1e-11
Identities = 129/680 (18%), Positives = 300/680 (44%), Gaps = 61/680 (8%)
Frame = -2
Query: 2227 LDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++IQKE+ I E LK + + DL+ E+ +++I SLS +L+ ++ E + R +
Sbjct: 3114 VEIQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI-SLSEDLKEQSEREGIDNTRTR 3172
Query: 2047 ----------------------EAEQTLLEAESER-ESLKAELEESISVLKQELSSARLQ 1937
E ++ ++E E ++ E +KAEL++ K EL + R
Sbjct: 3173 IKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNERQN 3232
Query: 1936 IESLEKELNQANEEVKVLSK--FRYQV----LELEEYSQQLSADLSKVHEDYSAALRQLF 1775
+E +L + E V+ L++ R QV +++E Q+ + + +K ++ L +L
Sbjct: 3233 LEEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQE--RVLIELK 3290
Query: 1774 DKKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVS 1595
+I +E +E + +EER++ + A ++ + L++ +S + I N
Sbjct: 3291 KTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDI---VNKTE 3347
Query: 1594 QLTLS----VDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFS 1427
QL L A +++++ +N ++ E + L + E +E +E S
Sbjct: 3348 QLRLREVELEQLQALIYRQQDEIEANRKAIINE-KYRLEGQKTEIDRLQREVNQMMEYAS 3406
Query: 1426 SVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSS-TGDNDPKAXXXXXXXXXX 1250
+LE KS++ + D + +G +E++ ++ + D K
Sbjct: 3407 KDRANLEKEKSEM-IAQKHQMDIELNKERGLIEERTQMLNTYEKEMDQKRTALEVEMKEL 3465
Query: 1249 XECRQNLENEECKSKQM--------EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLE 1094
+Q ++ E+ K +QM ++ K L+ + N + + + +L
Sbjct: 3466 KYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLAHLA 3525
Query: 1093 GDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAE 914
D + +++ + H A++ K L + M +++ +K++++ +D+ +
Sbjct: 3526 EDTKRKDDEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQQMQ 3585
Query: 913 GQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEIS 734
+ Q E+ SI + + + ++ + L+T+L+ + D++ ++ +E +
Sbjct: 3586 AEINRQQTEM-DTKKSI--IENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLTEKELLE 3642
Query: 733 STKEMLKDFIDNMEASDTNLQS---HFNQIQEMLLNQ---------NVNYPLEATVNIGF 590
S +++LK ++N++ ++S Q +E+L N+ ++ E I
Sbjct: 3643 SDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKL 3702
Query: 589 D-----QSMDEAVSEIAV-QTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQM 428
+ Q ++E ++I + + K ++I EI +++++ + Q +++ L++ +Q
Sbjct: 3703 ETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQN 3762
Query: 427 LKQQNTK-LELLAKKTSEMD 371
L+Q+ K E++ K SE+D
Sbjct: 3763 LQQELEKEKEIIMKDRSELD 3782
Score = 76.3 bits (186), Expect = 5e-11
Identities = 150/706 (21%), Positives = 304/706 (43%), Gaps = 71/706 (10%)
Frame = -2
Query: 2233 VRLDIQKEKNISEDLKET-------VKNLQSDLDIEQKLSTD--------------RQSE 2117
+++++QK+KN E+L+ T V+N + LD +QK D +SE
Sbjct: 13462 LQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSE 13521
Query: 2116 IYSLSAELERITQSEQMSLKRLKEAEQTLLE-----AESERESLKAE------LEESISV 1970
+ LS L Q EQ L+RL E E+ +E ESE++S++ E L+E + V
Sbjct: 13522 LNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIESEKQSIERERAELKRLKEEVEV 13581
Query: 1969 ------LKQELSSARLQIESLEKELNQANEEVKVL-SKFRYQVLELEEYSQQLSADLSKV 1811
L+Q+ + + + E LE E + EE+ L + + + EL+ ++++ A K
Sbjct: 13582 QHERTLLQQDKNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEA---KR 13638
Query: 1810 HEDYSAALRQLFD----KKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKK 1643
E+ L + + K E L+E I +K+ + ++ L + R + +L++
Sbjct: 13639 QEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQ-TSLDEI 13697
Query: 1642 LSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREI-RVET-- 1472
E + R LE V+ + V K E T S ++ + N ++E+ R++T
Sbjct: 13698 TKTDERRQRALEETVA----TTAKQPIVIKLEDTLTSEVQEMRDHLNNEIKELARMKTIM 13753
Query: 1471 ---KVTIQEARHNV----EEFSSVVKHLEYLKSQLE---TSNTMDHDTLSSTHQGSMEDK 1322
K +++A+ ++ EEF ++ KS+ E T D + LS+T +
Sbjct: 13754 KMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLD---KKN 13810
Query: 1321 ASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNA 1142
+++T K + ++N+ENE + KQ+E+ + +Q + + ++
Sbjct: 13811 KEIENNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQIEQEREIQRKAD--VTSTEK 13868
Query: 1141 EMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVE- 965
EM Y E + YK +L + +++ + S +EL + + + +
Sbjct: 13869 EM-----------YTEK--VTYKTELEDSKEKIKPDRDS-TLELTDTDSAKTDGEREAQT 13914
Query: 964 ---NVQKELLIWKDRAMIAEGQSKAFQ------LELKHANMSICSLSEKIQQIEEREKVL 812
VQ L + D E + LEL A + L E+ + EE + V+
Sbjct: 13915 LETKVQDVLQLTDDTTQDQEELHDEMENKMKIILELNKAKKDLQKLKEECRSAEEEKSVI 13974
Query: 811 LTQLSTKDTDMQHLAAQ-LTLAQE--EISSTKEMLKDFIDNMEASDTNLQSHFNQIQEML 641
+ L + ++ + ++ L+L QE ++ K ++ M+ ++ + + ++
Sbjct: 13975 MESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWE--TDVQ 14032
Query: 640 LNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKD-EEVIKLQ 464
+ Q P+E T +I +S +E ++ Q K + + +E+ D + E+V +++
Sbjct: 14033 IQQEGQEPIETTGHI-TKKSEEEISAKKTKQPIVTKLEDTLTSEVQEMRDMEIEDVARMK 14091
Query: 463 SQVENLQSLVQMLKQQ-NTKLELLAKKTSEMDPEKYFHFEELCQSL 329
+ ++ + ++ K ++E + E EK + E L Q L
Sbjct: 14092 TMMKMEKDQLEQAKSDIQRQMEEFERNMEETLKEKSRNEETLLQLL 14137
Score = 75.9 bits (185), Expect = 7e-11
Identities = 131/629 (20%), Positives = 268/629 (42%), Gaps = 25/629 (3%)
Frame = -2
Query: 2227 LDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
++IQKE+ I E LK + + DL+ E+ +++I SL ELE ++ E + R++
Sbjct: 2720 VEIQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI-SLREELEEQSEKEGIDKTRVR 2778
Query: 2047 EAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRY 1868
+Q + E E R ++ ELE + + KQ + R +IE ++ EL +E K K R
Sbjct: 2779 -IKQEMDELEQTRLNVVKELENN-ELQKQIIEDERDKIEQIKAEL---QKEAKDTEKQRQ 2833
Query: 1867 QVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIE------QKE------ 1724
+ ++++ L +D + ++ D++ + L++ +E +KE
Sbjct: 2834 DIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDLKK 2893
Query: 1723 --VEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
E + E L + R ++I + ++K+ E +L+ +S+ ++ F++
Sbjct: 2894 TNTEMKDLEKQLESQNRQHEIQLAEIQKEREILE----QLKLTLSKQKEDLEKERDCFEK 2949
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFS-SVVKHLEYLKSQLETSNT 1373
E +S +L ++ E RE +T+V I++ +++ +VVK LE +N
Sbjct: 2950 EKADISLREELQEQSE---REGIGKTRVRIKKEMDELKQTRLNVVKELE--------NNE 2998
Query: 1372 MDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEE 1193
+ + + KA Q D + + E L+NE+ K +
Sbjct: 2999 LQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEK-KDIETST 3057
Query: 1192 YKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIE 1013
++ E N + E + +++ D+ K K ++ QL +++ +I+
Sbjct: 3058 DRIRDEEANLEVQKQRLESDR-----DTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQ 3112
Query: 1012 LVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELK--HANMSICSLSEKIQ 839
LVE +QKE I + + Q + + E + SLSE ++
Sbjct: 3113 LVE--------------IQKEREILEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLK 3158
Query: 838 QIEEREKV--LLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSH 665
+ ERE + T++ + +++ L QE K++++D D +E L+
Sbjct: 3159 EQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKE 3218
Query: 664 FNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEI---AHTS 494
+ + L N+ N EA + D+ E+++E + + I TE+ A+ S
Sbjct: 3219 AEKTKLELQNERQNLE-EAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANES 3277
Query: 493 DK---DEEVIKLQSQVENLQSLVQMLKQQ 416
+K + +I+L+ V ++ + L+ Q
Sbjct: 3278 NKQMQERVLIELKKTVTDIAGAKEDLENQ 3306
Score = 75.9 bits (185), Expect = 7e-11
Identities = 137/684 (20%), Positives = 276/684 (40%), Gaps = 75/684 (10%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L ++ ++ KEK E++K+ VK + ++ E++ + + + I +
Sbjct: 8525 LQQMKNELNKEKEQVEEMKQMVKTERVKIEQEKE----------EMRKQTQEIEDGHEKL 8574
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVL 1883
K+ + A++ L +A SE + LK +L + + +Q++ ++E+ ++ L++ + E+
Sbjct: 8575 QKKTEIADKLLQDANSESDRLK-DLSMKLQMQRQDIEKTNTEMETKKRSLDRMSREL--- 8630
Query: 1882 SKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRE 1703
Q L + Y + L K+ E+ E +E+K +++R+++
Sbjct: 8631 --------------QDDKIRLKNDRDAYEKDMTHLELKREELVRETEDLERKILQQREQD 8676
Query: 1702 CMLAASERSNDINVNALE-------KKLSAYEGKIRRLENDVSQLTL--------SVDFS 1568
M ++R + ALE KK + + ++ + ++ +L L +
Sbjct: 8677 EM---AKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQESELE 8733
Query: 1567 AGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQL 1388
VF EE + A +E L E+ E R +EE + LE K+Q+
Sbjct: 8734 NRVFMEEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQREKEQLEISKNQI 8793
Query: 1387 ETSNTMDHDTLSSTHQGSME----DKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLEN- 1223
E D + S + +E +KA+ + + + R++LEN
Sbjct: 8794 E-QEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENC 8852
Query: 1222 ---EECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNH 1052
E + K+MEE + +++E+ K ++ E I E+LL
Sbjct: 8853 WVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSR---ENIESREEKINNKMEELL--- 8906
Query: 1051 GQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDR------AMIAEGQ------ 908
Q++ EM K E+ +++ + A +D+EN + E+ +D+ I E +
Sbjct: 8907 -QMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQ 8965
Query: 907 --------SKAFQLELKHANMSICSLSEKIQQIE------EREKVLLTQLSTK-DTDMQH 773
S+ +L++K M + + + Q+IE E+EK L Q + + M
Sbjct: 8966 LDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMD 9025
Query: 772 LAAQLTLAQEE---ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLL----NQNVN--- 623
L + +EE + + K L+D E L + I+EM L Q +N
Sbjct: 9026 LTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQT 9085
Query: 622 -----YPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTE--DINTEIAHTSDKDEEVI--- 473
E+ F+ + + EI+ + E D++ E+ D+ E++
Sbjct: 9086 REENKKEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDELEKIAYKT 9145
Query: 472 -KLQSQVENLQ----SLVQMLKQQ 416
K + +VE +Q S +Q ++QQ
Sbjct: 9146 NKERHEVEQMQAELHSQIQAIEQQ 9169
Score = 75.1 bits (183), Expect = 1e-10
Identities = 124/623 (19%), Positives = 263/623 (42%), Gaps = 12/623 (1%)
Frame = -2
Query: 2203 ISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTLLE 2024
I ++KE +K ++SD D+ +K D + L E + K+ + L E
Sbjct: 4348 IKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLE----------KQRKIKLAE 4397
Query: 2023 AESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQVLELEEY 1844
+ ERE L+ ++ E ++ ++ Q++ + EL+Q E++ L + ELE+
Sbjct: 4398 IQKEREDLE-KMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQQ------ELEKE 4450
Query: 1843 SQQLSADLSKVHEDYSAALRQL-FDKKNEITCLQEVIEQKEVEERQRECMLAASERSNDI 1667
+ + D S++ LRQ DK+ T + +++E + E +Q L + +
Sbjct: 4451 KEIIMKDRSQLD------LRQSELDKQQ--TNVNDIMETMKNERKQ----LDKDKEETEE 4498
Query: 1666 NVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLRE 1487
+EK+ ++ + L+ D+ + L V ++E +K+ + E+E E
Sbjct: 4499 QKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQ----VLEDEKSKLE---QMKIELEREAVE 4551
Query: 1486 IRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQS 1307
IR + K IQ R N+E+ + +K ++ N D + ++ ++ D +S
Sbjct: 4552 IR-KIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKS 4610
Query: 1306 STGDNDPKAXXXXXXXXXXXECRQNL--ENEECKSK------QMEEYKMLQAELNNWLSC 1151
+ + R+N+ + E+ ++K + +E + LQAE++
Sbjct: 4611 NLEE-----------------MRENISKQTEDVENKKENLRLREDELRQLQAEIHK---- 4649
Query: 1150 MNAEMGKFLCLCNSMVYLEGD---ILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYA 980
E+ K + +E + I+K EDL L + SLK+ ++ F
Sbjct: 4650 QQREIEK------EKINIESERAAIIKDVEDLQHKIICLDRDAESLKL---DREAF---- 4696
Query: 979 VLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQL 800
EN ++ L K + + +LE +H + ++ +IQ+ + L+ +
Sbjct: 4697 ----ENEKEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDEINNLIEET 4752
Query: 799 STKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNY 620
+ KD + + + I S K+ML+ ++E + +S +++E L Q N
Sbjct: 4753 NRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKT----RSELYKVKEDLEKQKENT 4808
Query: 619 PLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQS 440
E + M+E ++ ++ +I + + K +E+ +L+++++NLQ
Sbjct: 4809 LAEIQKEREDLEKMNENIT---------REMHEIKHQEEQMNQKQDELDQLKTEIQNLQQ 4859
Query: 439 LVQMLKQQNTKLELLAKKTSEMD 371
++ K E++ K S++D
Sbjct: 4860 ELEKEK------EIIMKDRSQLD 4876
Score = 75.1 bits (183), Expect = 1e-10
Identities = 131/671 (19%), Positives = 280/671 (41%), Gaps = 33/671 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
LD ++ ++Q E E++K + +++++ EQ+ + I +LE + +
Sbjct: 9496 LDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGDLEIMRADYE-- 9553
Query: 2062 LKRLKEAEQTLLEAESERESL---KAELEESISVLKQELSSARLQIESLEKELNQANEEV 1892
K+ ++ E+ +EA+ ER+ L K+ELE+ + + E +EKE N
Sbjct: 9554 -KQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKERNDLE--- 9609
Query: 1891 KVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQ--KEVE 1718
K+ S+ Q ++E+ +L + + + + K++I +E++E+ EVE
Sbjct: 9610 KMKSELMTQRQQMEDERSELDQKIKEANTE-----------KDKIEKNKEIVERLMAEVE 9658
Query: 1717 ERQRECML----AASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
E++ + L A ER N ++ L L+ E +++ + + E
Sbjct: 9659 EQRNDFKLKKEELALERQNIVDEKYL---LAQCETELQNKSEQIRNM------------E 9703
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTM 1370
E+ K N + L+E E L+ + E K I+E E+ + + K +L+
Sbjct: 9704 EAVK--NERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKK-- 9759
Query: 1369 DHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEY 1190
DTL + Q + D + R+ E + K+MEE
Sbjct: 9760 --DTLEQEREEINHKWTQFQQRIDEFDAQV-------------RKQKEEDLTNQKKMEEE 9804
Query: 1189 KMLQAELNNWLSCMNA----EMGKFLCLCNSMVYLEGDILKYKED---LLLNHGQLRAEM 1031
+ E+N + M E + + L+ I+K KE + + R ++
Sbjct: 9805 RKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAMTIKLKMEREDL 9864
Query: 1030 SSLKIELVEKNGFMGYAVLDVENVQKEL-----LIWKDRAMIAEGQSKAFQLELKHANMS 866
+K ELV + +V++ QK+L +I +++ + + +S+ + +
Sbjct: 9865 DQIKSELVREK-------TEVDHEQKKLNDDIKMIEQEKEDLEKMKSE-IMTQKQEMEKE 9916
Query: 865 ICSLSEKIQQIE------EREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFI 704
L KIQQ + E+ K ++ +L + + +H ++ L +EE+ ++ + D
Sbjct: 9917 RSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRH---EIQLQKEELDIERQKIADEQ 9973
Query: 703 DNMEASDTNLQSHFNQIQEMLLNQNVNYPLEA--TVNIGFDQSMDEAVSEIAVQTFPNKD 530
D + + + LQ+ +I+ +N+ + E + ++ +E S +D
Sbjct: 9974 DLLIQNKSELQNENERIRN--INEVIKKERETLKEMEAHLEKEKEEMKSITEETRRQKED 10031
Query: 529 TEDINTEIAHTSDKDEEVIK----LQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEK 362
E ++T+I +++++++K L+ + E++ L+Q+ + + K E D K
Sbjct: 10032 LEKMSTDI---KEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQVSKQKEEDLTK 10088
Query: 361 YFHFEELCQSL 329
+E +SL
Sbjct: 10089 QKEMKEERKSL 10099
Score = 75.1 bits (183), Expect = 1e-10
Identities = 132/702 (18%), Positives = 287/702 (40%), Gaps = 68/702 (9%)
Frame = -2
Query: 2245 TLDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLST-------DRQSEIYSLSAELER 2087
TL + ++KEK + + E + + DL +K+ST D +S+ L E E
Sbjct: 11395 TLKEMEAYLEKEKEEMKSITEETRRQKEDL---EKMSTHINEQKQDLRSQRDLLEQEREE 11451
Query: 2086 ITQSEQMSLKRL--------KEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIE 1931
I + +R+ K+ E+ L + + +E K+ E ++L+ + + + E
Sbjct: 11452 INHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMK---TKAEPE 11508
Query: 1930 SLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITC 1751
++KE + EE ++ K + E+E Q+ + L +V + ++L D K I
Sbjct: 11509 EIKKEKEKEEEEQEMRVKVEMERKEIE----QIKSQLERVRSEMDHEQKKLNDDKKMIEQ 11564
Query: 1750 LQEVIE--QKEVEERQRECMLAASERSNDINVNALEK-KLSAYEGKIRRLENDVSQLTLS 1580
+E +E + E+ +++++ SE I LEK + + + +L +V +
Sbjct: 11565 EKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHE 11624
Query: 1579 VDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYL 1400
+ F E K+++ DLL ++ K+ Q ++E +K
Sbjct: 11625 IQFQKEELDIERQKIADEQDLL-----------IQNKIEQQNENERIKEMDEEIKKERET 11673
Query: 1399 KSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE 1220
++E + + + + S + + K + + D + + +Q+L N+
Sbjct: 11674 LKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQ--------------KQDLMNQ 11719
Query: 1219 ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGD-----------ILKYK 1073
KQ E E+N+ L+ + + +F N +V + + +K
Sbjct: 11720 RDLLKQERE------EMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEY 11773
Query: 1072 EDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQ 893
E ++ + R E+ ++++ ++N + +E +K+ K+R E Q +A
Sbjct: 11774 ESIIEETNRKRTELEEIEVDQSQQNKNVETMKDLLEKERKD--TEKER---EELQKQADD 11828
Query: 892 LELK------HANMSICSLSEKIQQIEEREKVLLTQ---LSTKDTDMQHLAAQLTLAQEE 740
LE++ MS SL E+ + +E++ +L Q L + DM +L Q+E
Sbjct: 11829 LEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKE 11888
Query: 739 ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSE 560
I + K +++ +E + +++E L N V + +++ + + E
Sbjct: 11889 IQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKHQQQ-IEE 11947
Query: 559 IAVQTFPNKDTED----------------------INTEIAHTS---DKDEEVIKLQSQ- 458
+ V+T +D D + E+ T D EE +KL+ Q
Sbjct: 11948 MRVKTKMERDELDQLMAKMLMDRKENERSKDMIGLLKKEMEQTKFNLDAQEEELKLEKQK 12007
Query: 457 VENLQSLVQM----LKQQNTKLELLAKKTSEMDPEKYFHFEE 344
++N + ++M +K++ ++++ L ++ E D + + +E
Sbjct: 12008 IQNEKKDLEMFKAEIKREASEVKTLKEQQLEKDTKAFEALKE 12049
Score = 75.1 bits (183), Expect = 1e-10
Identities = 125/644 (19%), Positives = 282/644 (43%), Gaps = 28/644 (4%)
Frame = -2
Query: 2218 QKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELE-RITQSEQMSLKRLKEA 2042
+KEK+ +++ ++++S ++ +L T+ ++I +++EL+ R + E + K+ KE
Sbjct: 12912 RKEKHAEAEIQRQFEDIES---VKVRLVTE-SNQIDKMNSELKTRSEELENLIKKQQKEF 12967
Query: 2041 EQTLLEAESERESLK---AELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFR 1871
E E + ER++L+ AELE + LK ++ + L+KE N+ E +L + +
Sbjct: 12968 ETKENEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREK 13027
Query: 1870 YQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-----TCLQEV-IEQKEVEERQ 1709
++ + + QQ ++ + + + + L +NE+ + L + +E+ E+++ +
Sbjct: 13028 SELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLK 13087
Query: 1708 RECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSN 1529
E + + + S + L++ E K +L+N + ++ + + +E+ +
Sbjct: 13088 TE--IQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMD---KLSIQREKDSLEEI 13142
Query: 1528 ACDLLQEIENFLREIRVETKVT--IQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTL 1355
DL ++ E E+R ++T I + +++ + L +++ +E + L
Sbjct: 13143 KADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQAKI----L 13198
Query: 1354 SSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSK-QMEEYKMLQ 1178
S Q +K + S +ND R++LE + ++ ++E + +
Sbjct: 13199 ESDVQLLQTEKEILEKSKTEND--------------LLREDLEKQRKRNDLTLQELRKEK 13244
Query: 1177 AELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKN 998
L ++ + E L N V L+ LK KE L + R EM L+++L +
Sbjct: 13245 MALEQMITDITKEKDAVASLQNE-VSLKQHELKNKETEL---DEQRKEMDDLRMQLEMRQ 13300
Query: 997 GFMG-----YAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELK----HANMSICSLSEK 845
V VEN++ + + ++ E + + Q +K N+ S ++
Sbjct: 13301 NSTNKQQQEVDVFIVENMKMRNDLESMKTLLDE-ERRQLQDNIKTFEDQKNVLHPSKTDA 13359
Query: 844 IQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSH 665
+QQ +E EK T + T+ ++ ++ + +EI +KE L+ +E +
Sbjct: 13360 VQQTDELEK-FTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGK 13418
Query: 664 FNQIQEMLLNQNVNYPLEATVNIGFD--QSMDEAVSEIAVQTFPNKDTEDINTEIAHTSD 491
QI+ + L A + G D +++ + ++A++ K ++ + +
Sbjct: 13419 RAQIESL-------EQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKN 13471
Query: 490 KDEEVIKL----QSQVENLQSLVQMLKQQNTKLELLAKKTSEMD 371
+ EE+ + QVEN + + + KQQ +++ SE D
Sbjct: 13472 ELEELRNTIEAEKHQVENRK--IMLDKQQKEVEDIMTVIKSERD 13513
Score = 72.8 bits (177), Expect = 6e-10
Identities = 145/702 (20%), Positives = 296/702 (42%), Gaps = 82/702 (11%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSE--------- 2072
+IQKE+ I E LK T+ + DL+ E+ +++I SL EL+ ++ E
Sbjct: 2918 EIQKEREILEQLKLTLSKQKEDLEKERDCFEKEKADI-SLREELQEQSEREGIGKTRVRI 2976
Query: 2071 --------QMSLKRLKEAEQTLLE---AESER---ESLKAELE---ESISVLKQELSSAR 1943
Q L +KE E L+ E ER E +KAEL+ E ++++ R
Sbjct: 2977 KKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDR 3036
Query: 1942 LQIESLEKELNQANEEVKV-LSKFRYQVLELEEYSQQLSAD-----------------LS 1817
E + +L ++++ + R + LE Q+L +D +
Sbjct: 3037 RNNEEMVIKLQNEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKERFDLEKTKTEMG 3096
Query: 1816 KVHEDYSAALRQLFDKKNEITCLQEVIE--------QKEVEERQRECMLAASERSNDINV 1661
+ + + +RQ + EI +E++E QKE E++R+C + DI++
Sbjct: 3097 NLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCF---EKEKADISL 3153
Query: 1660 NALEKKLSAYEGKIRRLENDVSQLTLSVD----FSAGVFKEESTK------VSNACDLLQ 1511
+ K+ S EG ++N +++ +D + KE+ + + D ++
Sbjct: 3154 SEDLKEQSEREG----IDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIE 3209
Query: 1510 EIENFLREIRVETKVTIQEARHNVEEFSSVVK----HLEYLKSQLETSNTMDHDTLSSTH 1343
+I+ L++ +TK+ +Q R N+EE + +K ++E L +L + + T
Sbjct: 3210 QIKAELKKEAEKTKLELQNERQNLEEAGTKLKKDRENVESLAEELGRKQVVLENMQIET- 3268
Query: 1342 QGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNN 1163
M+ KA ++S+ + +++LEN+ + + E+ K+ QAE+
Sbjct: 3269 --EMQRKA-NESNKQMQERVLIELKKTVTDIAGAKEDLENQLLEER--EKNKVKQAEI-- 3321
Query: 1162 WLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQL----------RAEMSSLKIE 1013
AE L + + DI+ E L L +L + E+ + +
Sbjct: 3322 -----QAEKDMLYLLKQGISEQQVDIVNKTEQLRLREVELEQLQALIYRQQDEIEANRKA 3376
Query: 1012 LVEKNGFMGYAVLDVENVQKEL-----LIWKDRAMIAEGQSKAFQLELKHANMSICSLSE 848
++ + + +++ +Q+E+ KDRA + + +S+ + KH M I L++
Sbjct: 3377 IINEKYRLEGQKTEIDRLQREVNQMMEYASKDRANLEKEKSE--MIAQKH-QMDI-ELNK 3432
Query: 847 KIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQS 668
+ IEER ++ L+T + +M L + +E+ K+ +++ + ++ LQ
Sbjct: 3433 ERGLIEERTQM----LNTYEKEMDQKRTALEVEMKELKYHKQAIQEEKNKLQQMKIELQR 3488
Query: 667 HFNQIQEML-LNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSD 491
+ I+++ +N LE ++ D+ ++ +A T D + E A +D
Sbjct: 3489 EADDIKKLKEKTRNERQSLEKMAE-NLEKEKDD-LAHLAEDTKRKDDEMKVLHESA-LAD 3545
Query: 490 KDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPE 365
+E L+ E++ +M+ + K+ L K +M E
Sbjct: 3546 IQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQQMQAE 3587
Score = 70.9 bits (172), Expect = 2e-09
Identities = 105/631 (16%), Positives = 253/631 (40%), Gaps = 12/631 (1%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L+ V +IQ+EK + + + +L+ + +RQ +I + +LE E+
Sbjct: 9303 LNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLE-----EEKL 9357
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEES-ISVLKQELSSARLQIESLE---KELNQANEE 1895
L +++ + E +R+ K E+ E+ + V+K++ +AR + E + +E Q NE
Sbjct: 9358 LVQIEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNEN 9417
Query: 1894 VKVL-----SKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-TCLQEVIE 1733
K L Q EL++ + L + E+ + R L ++K + E++
Sbjct: 9418 AKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILR 9477
Query: 1732 QKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFK 1553
Q++ E+++E M+ KL + +++ + ++ +D
Sbjct: 9478 QRDDLEKEKEDMMKK------------WNKLDVLQNEMQNENKAMEEIKYELDGKRNEIN 9525
Query: 1552 EESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNT 1373
+E ++ + + E + L +R + + Q+ E K L+ +KS+LE T
Sbjct: 9526 KEQQRLEESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKT 9585
Query: 1372 -MDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQME 1196
+D++ + +M +K + ++ RQ +E+E
Sbjct: 9586 EIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQ------------RQQMEDE-------- 9625
Query: 1195 EYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKI 1016
++EL+ + N E K + L ++ + + D L +L E +
Sbjct: 9626 -----RSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQRNDFKLKKEELALERQN--- 9677
Query: 1015 ELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQ 836
+V++ + +++N +++ + + +K+ ++ +Q+
Sbjct: 9678 -IVDEKYLLAQCETELQNKSEQI--------------RNMEEAVKNERETLKETEAHLQR 9722
Query: 835 IEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQ 656
++ K ++ + S + D++ ++ + + ++E+ + K+ L+ + + T Q ++
Sbjct: 9723 DKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDE 9782
Query: 655 IQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDE-E 479
+ Q ++ + M+E K E++N +I K E E
Sbjct: 9783 FDAQVRKQKEE-------DLTNQKKMEE----------ERKCLEEVNGKIIEMKTKAELE 9825
Query: 478 VIKLQSQVENLQSLVQMLKQQNTKLELLAKK 386
++ ++E LQ+L + + ++ K E + K
Sbjct: 9826 HHEINQKIEELQTLQEQIMKEKEKAEAMTIK 9856
Score = 70.5 bits (171), Expect = 3e-09
Identities = 135/717 (18%), Positives = 295/717 (41%), Gaps = 94/717 (13%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKETVKNLQSD-------LDIEQKLSTDRQSEIYSLSAELERIT 2081
D R DI+ K I + L V+ + D LDIE++ D Q + A+L+
Sbjct: 11042 DLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNEN 11101
Query: 2080 QSEQMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQAN 1901
+ + + +K+ ++TL E E+ L+ E EE SV+++ + +E + ++N+ N
Sbjct: 11102 ERIKEMDEEIKKEKETLKEMEAH---LRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQN 11158
Query: 1900 EEV----KVLSKFRYQV----LELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQ 1745
+++ +L + R ++ +L++ + A +SK E+ +++ +++ + +
Sbjct: 11159 QDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETK 11218
Query: 1744 -EVIE----------QKEVEERQRECMLAASERSND-------------INVNALEKKLS 1637
++IE +KE E+ + E M A E + ++ +KKL+
Sbjct: 11219 IKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLN 11278
Query: 1636 AYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSN--------ACDLLQEIENFLREIR 1481
+ I + + D+ ++ + +EE +++ N CD IEN +EI
Sbjct: 11279 DDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCD----IEN-SKEIV 11333
Query: 1480 VETKVTIQEARHNVE--------EFSSVVKHLEYL---KSQLETSN----------TMDH 1364
+ V ++E +H ++ E + + L KS+L+ N +
Sbjct: 11334 QKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKER 11393
Query: 1363 DTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEE--- 1193
+TL ++K +S T + + E +Q+L ++ +Q E
Sbjct: 11394 ETLKEMEAYLEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEIN 11453
Query: 1192 --YKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLK 1019
+K LQ ++ + + ++ + + L M + + K ++L + +AE +K
Sbjct: 11454 HKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANIL--EMKTKAEPEEIK 11511
Query: 1018 IELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQ 839
E EK + VE +KE+ K + + Q +L I E ++
Sbjct: 11512 KE-KEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLE 11570
Query: 838 QIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFN 659
+++ Q+ + +++ Q L + +I ++KE+++ + +E +Q
Sbjct: 11571 KMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKE 11630
Query: 658 QI----------QEMLLNQNVNYPLEATVNIGFDQSMD---EAVSEIAVQTFPNKDTEDI 518
++ Q++L+ + E D+ + E + E+ V K+ E+I
Sbjct: 11631 ELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNL--QKEKEEI 11688
Query: 517 NTEIAHTSDKDEEVIKLQS----QVENLQSLVQMLKQQ----NTKLELLAKKTSEMD 371
+ I T + E++ K+ + Q ++L + +LKQ+ N KL L ++ E +
Sbjct: 11689 ESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFE 11745
Score = 70.1 bits (170), Expect = 4e-09
Identities = 138/668 (20%), Positives = 268/668 (40%), Gaps = 40/668 (5%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L +++++Q+E + + LKE +N + L +K++ + + E L A L T+ +
Sbjct: 3479 LQQMKIELQREADDIKKLKEKTRNERQSL---EKMAENLEKEKDDL-AHLAEDTKRKDDE 3534
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVL 1883
+K L E+ ++ E K LE+ +++ + I+S +K++ +L
Sbjct: 3535 MKVLHESALADIQKE------KCNLEQ----MRESMFKQNEMIDSEKKKM--------IL 3576
Query: 1882 SKFRYQVLELEEYSQQLSADLSK--VHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQ 1709
+ + Q ++ E QQ D K + + +A ++ D E+T E +E + E
Sbjct: 3577 REDKLQQMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLT 3636
Query: 1708 RECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSN 1529
+ +L + + +V L++KL E L+ D L + V K+ T
Sbjct: 3637 EKELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELL----ENEKEVLKQMKT---- 3688
Query: 1528 ACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS-VVKHLEYLKSQLETSNTMDHDTLS 1352
DL E E + +I++ET Q R VEE ++ + K EYL+ + HD
Sbjct: 3689 --DLQGEAEE-IEKIKLET----QHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKY 3741
Query: 1351 STHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-ECKSKQMEEYKMLQA 1175
Q + Q T +Q LE E E K E + Q+
Sbjct: 3742 QEKQMKQKQDELDQLKT---------------EIQNLQQELEKEKEIIMKDRSELDLKQS 3786
Query: 1174 EL-------NNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKI 1016
EL N+ + M E + M + +I K K D L ++ +K+
Sbjct: 3787 ELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKL 3846
Query: 1015 E---LVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSE- 848
+ E+ + +++E E+ K+ + ELK S L+E
Sbjct: 3847 QKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESFTHLAED 3906
Query: 847 --KIQQIEEREKV----LLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEAS 686
K Q+I + KV L+ +L + ++ + + ++ E++ + KE L+ D +
Sbjct: 3907 TKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLREDELGQL 3966
Query: 685 DTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQ-----SMDEAVSEIAV--QTFPNKD- 530
+ +I++ N+ A + I D S+D + + + F N+
Sbjct: 3967 QAEIHKQQREIEKE--KSNIESERAAIIKIVEDLQHKIISLDRDAESLKLDREAFENERE 4024
Query: 529 -TEDINTEIAHTSDKDEEVIKLQSQVEN----------LQSLVQMLKQQNTKLELLAKKT 383
+ + TE+ +D+ E+ IKL++Q E ++++ KQ N E + ++
Sbjct: 4025 VLKQMKTELEREADEIEK-IKLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQEQK 4083
Query: 382 SEMDPEKY 359
EM+ E++
Sbjct: 4084 QEMEKERH 4091
Score = 67.4 bits (163), Expect = 3e-08
Identities = 132/650 (20%), Positives = 266/650 (40%), Gaps = 34/650 (5%)
Frame = -2
Query: 2224 DIQKEK-NISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLK 2048
+I EK NI + ++ Q+ + +K S D + ++ + E E + + K ++
Sbjct: 6203 EIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVE 6262
Query: 2047 EAEQTLLEAESERESLKAE---LEESISVLKQELSSARLQIESLEK-ELNQANEEVKVLS 1880
+ +Q L+ E + ESLK + E +KQ + ++Q + +EK +L +E +V
Sbjct: 6263 DLQQKLMSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRV-- 6320
Query: 1879 KFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI-TCLQEVIEQKEVEERQRE 1703
++ +A + K E+ + + ++ K++ I E+ ++KE E R
Sbjct: 6321 -------------EEKTAQIQKEREEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRS 6367
Query: 1702 CMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNAC 1523
+ A ++ N N +E L+ + K LE +S + S K E
Sbjct: 6368 DLEKAKSQTFKQNKN-IEIALAEIQQKRNALEK------MSKEISRDRMKLE-------- 6412
Query: 1522 DLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTH 1343
+ K IQ AR +E ++ + K L S D L +
Sbjct: 6413 ---------------DEKKEIQLAREELERMHGDMQRQQEAKDHL-LSGITDESLLKKSE 6456
Query: 1342 -----QGSMEDKA----SSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEEC-------- 1214
Q S DKA ++ S D P +++ E+E+
Sbjct: 6457 AEIVLQPSQVDKAKPARKTEISDSDKQPVFVQQMPEMDLKDALKKDFESEKLDLPKVKDV 6516
Query: 1213 --KSKQME-EYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQL 1043
+ +QM+ E K+++ E++ L M AE+ K E D ++ K+ + N Q
Sbjct: 6517 LPQDQQMKLEQKLIEDEMDK-LKQMRAELQK-----------EADQIEKKKQDMQNERQK 6564
Query: 1042 RAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLE---LKHAN 872
+M++ E N E + +E+ I K + + Q+ AFQ+E +
Sbjct: 6565 LDDMAARLQEERRTN----------ERLNEEINIQK---VNQQKQATAFQMEKTDFERIK 6611
Query: 871 MSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNME 692
I ++++ +E+ K +T++ + ++ + A ++ E I++ + L
Sbjct: 6612 TEIDQANKELADQQEKNKKTITEMQKERETLEEMRANISKQVETITNENKSL-------- 6663
Query: 691 ASDTNLQSHFNQIQEMLLNQNVNY-PLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDI- 518
++ +S ++QE +L Q L+ T+ + Q +D+ S+I + K+ +D+
Sbjct: 6664 ---SSRESELAKLQEDILQQQQEMDELKNTIMMEMCQ-LDQRQSDIDLL---QKEVDDLM 6716
Query: 517 ---NTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSE 377
TE+A+ + E +++ +Q N++S + LK + E L K +E
Sbjct: 6717 DFTKTEMANV---ERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNE 6763
Score = 67.0 bits (162), Expect = 3e-08
Identities = 116/631 (18%), Positives = 263/631 (41%), Gaps = 25/631 (3%)
Frame = -2
Query: 2188 KETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTLLEAESER 2009
+E + +++++DIE+ + + ELE+I Q +AE E
Sbjct: 12521 REELAKMKTEIDIERDEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQHDEIHGGI 12580
Query: 2008 ESLKAELEESISVLKQELSSARLQIESLEKELNQANEEV-KVLSKFRYQVLELE--EYSQ 1838
+SLK E EE I +K +L + + E++ + + +E+ K ++ +E E + +
Sbjct: 12581 DSLKEEREE-IEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDK 12639
Query: 1837 QLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECMLAASERSNDINVN 1658
L ++ K+ A L+ +KN + + E + +E E + C + E++ ++N
Sbjct: 12640 NLQDEMMKI----EAILKVTKKQKNYLEQMNENL-TREKTELETNCQMLEREKT-ELNKK 12693
Query: 1657 ALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRV 1478
E + + K+ E + + +D A EE K+ +E+ N EI+
Sbjct: 12694 VKETE-EFHMSKMEEREAERKTIERVMDEMA----EEHEKIKKE---REELVNMEEEIKK 12745
Query: 1477 ETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTG 1298
+ +V ++ E + L++ +S+L D ++S + ++ + S Q
Sbjct: 12746 QRRV----LEESMNEMTKKKSELQHERSELYKQKQQLEDMIASESKRDVDTERSRQDKED 12801
Query: 1297 DNDPKAXXXXXXXXXXXECRQNLENEECK---SKQMEEYKMLQAELNNWLSCMNAEMGKF 1127
+ K ++ + E K +++ E + +Q++LN+ M+ E K
Sbjct: 12802 EQILKREREEIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKL 12861
Query: 1126 LCL-------CNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDV 968
L + N++ + D+ K +E++ Q + E I + E +A ++
Sbjct: 12862 LYMKTEIQVKTNALEKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEI 12921
Query: 967 ENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKD 788
+ +++ K R + Q ELK + SE+++ + ++++ + TK+
Sbjct: 12922 QRQFEDIESVKVRLVTESNQIDKMNSELK-------TRSEELENLIKKQQ---KEFETKE 12971
Query: 787 TDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEM--LLNQNVNYPL 614
+MQ L E+ LK+ I+ + + +LQ N+ +E+ +L + +
Sbjct: 12972 NEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREKSELY 13031
Query: 613 EATVNIGFDQSMDEAVSEIA------VQTFPNKDTEDINTEIAHTSDKDEEVIKL----Q 464
+ + + E + + ++ N+ ++ + ++ S + E+ KL Q
Sbjct: 13032 QEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTEIQ 13091
Query: 463 SQVENLQSLVQMLKQQNTKLELLAKKTSEMD 371
S+ E+++ + LKQ + E K +++D
Sbjct: 13092 SEKESIEEEKKTLKQLKDENE---SKRTQLD 13119
Score = 65.9 bits (159), Expect = 7e-08
Identities = 135/678 (19%), Positives = 282/678 (41%), Gaps = 63/678 (9%)
Frame = -2
Query: 2239 DAVRLDIQKEKNISEDLKE-------TVKNLQSDLDIEQKLSTDRQSEIYSLSAELERIT 2081
D + I KEK S ++E T + + +++ E++ RQ E+ E+ERI
Sbjct: 546 DVEKAKILKEKEESIRIREEARQERETTELVNAEIKAEKERLNQRQEEMLRERQEIERIK 605
Query: 2080 QSEQMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQAN 1901
+ + ++ ++ + + E +KAE++ I +++++ + E +E+ +
Sbjct: 606 HETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKEQMEEAKVELE 665
Query: 1900 EEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITC---------- 1751
EE + L + R V E ++ L ++ +V E+ + R+ ++ E+
Sbjct: 666 EEREDLERKRDLVSREIEQAEFLRNEILRVKEEMESRWRETETEEVELRAKTQHELERLE 725
Query: 1750 -LQEVIE--QKEVEERQRECML-------AASERSNDINVNALEKKLSAYEGKIRRLEND 1601
L+E E QK +EE + E ML E D +V ++ ++ + K +L
Sbjct: 726 KLREETERSQKNIEESKIELMLWKESLDKLKGEMEEDKHVVIMQ--MNEAKAKEEQLTMV 783
Query: 1600 VSQLTL---SVDFSAGVFKEESTKVSNACDLLQ----EIENFLREIRVETKVTIQEARHN 1442
+ QL + + S KEE +++ + LQ E+E++ R + E K A+
Sbjct: 784 IEQLEIERGEITISREKVKEELDEINRMRNELQRQHAEMEDWFRVVNKE-KEEANLAKLA 842
Query: 1441 VEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXX 1262
V E + LK Q+E S ++ ++ ++E + Q KA
Sbjct: 843 VHEAEML------LKKQMEESEKRRYEMITE----ALEQRDEIQK-------KAEELEQI 885
Query: 1261 XXXXXECRQNLE-----NEECKSKQME---EYKMLQAELNNWLSCMNAEMGKFLCLCNS- 1109
RQ LE +E K +E + ++ ++ + L A+ K L +S
Sbjct: 886 NKEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLFEMDSE 945
Query: 1108 ---MVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLI- 941
+ + + K+DL Q R EM VE++ + ++E ++ +L+I
Sbjct: 946 RKELEQMRFQVENEKKDL----EQRRYEMMRYD---VEQSAQVQRQKEELEKIKSQLVID 998
Query: 940 ----WKDRAMIAEGQSKAFQL--ELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDM 779
+ R + + + KA L E++ + E+ +Q EE ++L + + D+
Sbjct: 999 TESMNRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRLLRKDMENEREDL 1058
Query: 778 QHLAAQLTL--------AQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVN 623
+ + + TL +EEI+ + ++ D E D + N +E ++ +
Sbjct: 1059 EKIRVE-TLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRK--- 1114
Query: 622 YPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIK--LQSQVEN 449
+EA + M E + ++ V+ K+ D+ E A + E++K L Q E+
Sbjct: 1115 --MEA-----MKREMGE-IEDMKVELTKQKENIDMKMEHARLEMTNLEMMKADLLRQKED 1166
Query: 448 LQSLVQMLKQQNTKLELL 395
+++ + K + ++E++
Sbjct: 1167 IENQMLAAKSERQQMEVM 1184
Score = 65.5 bits (158), Expect = 1e-07
Identities = 142/774 (18%), Positives = 319/774 (41%), Gaps = 66/774 (8%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
+++ ++ + ED K ++N++ +L E + ++ +E + + + L++
Sbjct: 1805 NLEAQRKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEK 1864
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQ 1865
+ + ++ER +LE + + L+ + + + LEK +++ N + K +
Sbjct: 1865 KRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEK-ISELNSQQKDEIENEKS 1923
Query: 1864 VLELEEYS-QQLSADLSKVHEDYSAALRQLFDKKNEITCLQ-EVIEQ-KEVEERQRECML 1694
+++ EY QQ+ DL++ ++ +F +K+E+ Q E+ EQ K+V + +
Sbjct: 1924 KIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQDEIAEQLKQVGDMMQ---F 1980
Query: 1693 AASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLL 1514
+E+ N L+++ +A + ++E D++ L S + K+E V N LL
Sbjct: 1981 TQNEKDN------LDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKE---VLNEKRLL 2031
Query: 1513 QEIE-NFLREIR--VETKVTIQEARHNVE-EFSSVVKHLEYLKSQLET----SNTMDHDT 1358
++ + +R+++ + K+ ++ + ++ + S+ + + L+S L+T + + DT
Sbjct: 2032 EDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDT 2091
Query: 1357 LSSTHQGSMEDKA---------------SSQSSTGDNDPKAXXXXXXXXXXXECRQNLEN 1223
L+ + +ED A ++ D D + + +L+
Sbjct: 2092 LAEKQK--LEDAAVELQKERDEIMNIAEETKRKREDVDKIRVGIEKQEITFKDLKADLQK 2149
Query: 1222 E--------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKED 1067
E + K ++ K ++ ++ M+ + + ++ ++ ++ K +++
Sbjct: 2150 EAAIVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVDKERQE 2209
Query: 1066 LLLNHGQLRAEMSSLKIE------LVEKNGFMGYAV--------LDVENVQKELLIWKDR 929
+ +L E S L+ + EKN + + L EN+ KE I
Sbjct: 2210 VESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTI---- 2265
Query: 928 AMIAEGQSKAFQLELKHANMSICSLSEKIQQIEE------REKVLLTQLSTKDTDMQHLA 767
F+LE +H + K +QI+E EKV + Q+ D D Q
Sbjct: 2266 ----------FELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQA-DKDQQRKK 2314
Query: 766 AQL--------TLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLE 611
A+ T A EE E L++ +N+E + H N+ +E+ ++ + +E
Sbjct: 2315 AEYVKTARGRETTALEEQRQEMESLREEYENVEKQ----KKHVNEQKELFESRMKSLEME 2370
Query: 610 ATVNIGFDQSMDEAVSEIAVQ-TFPNKDTEDINTEIAHTSDKDEEVIK-LQSQVENLQSL 437
+ + +D+ ++ Q K+ + + TE+ ++ E K L+ Q + +
Sbjct: 2371 NEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTE 2430
Query: 436 VQMLKQQNTKLELLAKKTSEMDPEKYFHFEELCQSLVXXXXXXXXXXXXXXXKNQVLVKQ 257
ML+ Q +E KT E+D + +L S V + + VK+
Sbjct: 2431 TYMLETQKPVVE--KSKTDELDEVRKKINADL--SEVEKQKSALVQMNLKISQEESYVKK 2486
Query: 256 VKEMQVTLQSESPMEGETDSISENAIGSQPA--GKLSTELHNVHGNTERVPLQL 101
K+ ++E M+ + +N + + A K EL NV E+ +++
Sbjct: 2487 EKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEI 2540
Score = 65.5 bits (158), Expect = 1e-07
Identities = 135/673 (20%), Positives = 272/673 (40%), Gaps = 57/673 (8%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQ--------KLSTDR---QSEIYSLSAELERITQ 2078
D+QKEKN +E+LK ++ +S+L E+ ++ T R +SE+ +L +
Sbjct: 13008 DLQKEKNKTEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELED 13067
Query: 2077 SEQMSLKRLK----EAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELN 1910
++ L RL E ++ E +SE+ES++ E ++++ LK E S R Q+++ +++N
Sbjct: 13068 EKKSMLSRLSMEKHEIDKLKTEIQSEKESIEEE-KKTLKQLKDENESKRTQLDNTIEKMN 13126
Query: 1909 ----------QANEEVKVLSKFRYQVLELE-----EYSQQLSADLSKVHED--------- 1802
+ EE+K + + + L+ E + + Q+S D + +D
Sbjct: 13127 MDKLSIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRS 13186
Query: 1801 -YSAALRQLFDKKNEITCLQ---EVIEQKEVEERQRECMLAASERSNDINVNALEKKLSA 1634
+ RQ ++++ LQ E++E+ + E L + ND+ + L K+ A
Sbjct: 13187 MRADIERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEKQRKRNDLTLQELRKEKMA 13246
Query: 1633 YEGKIRRLEND---VSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVT 1463
E I + + V+ L V K + T++ + ++ L + T
Sbjct: 13247 LEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQ 13306
Query: 1462 IQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPK 1283
QE + E + LE +K+ L+ D + + S + D
Sbjct: 13307 QQEVDVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDEL 13366
Query: 1282 AXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMV 1103
+ E + +K++ + K LN + E+ S+
Sbjct: 13367 EKFTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLE 13426
Query: 1102 YLEGDILKYKED---LLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWK- 935
L D+L +D L+ Q+ E + K E VE + ++E ++ + K
Sbjct: 13427 QLRADLLAGADDIKTLVQTEKQMAIEDTEKKTE-VELQMNLQKQKNELEELRNTIEAEKH 13485
Query: 934 ---DRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAA 764
+R ++ + Q K + I ++ + + + E+EK L +LS L
Sbjct: 13486 QVENRKIMLDKQQKEVE--------DIMTVIKSERDVLEKEKSELNKLS------HVLNE 13531
Query: 763 QLTLAQEEISSTKEMLKDFIDN----MEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNI 596
++ QEE+ E +D I+N +E+ +++ +++ L + V E T+ +
Sbjct: 13532 KVQREQEELERLLEKERDDIENCKKIIESEKQSIERERAELKR--LKEEVEVQHERTL-L 13588
Query: 595 GFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQ 416
D++M + K+ E + E A T+ EE+ L+ +++ S + ML +
Sbjct: 13589 QQDKNMIQ------------KEKEHLEGEKARTT---EEIHNLKEEIKRKSSELDMLNK- 13632
Query: 415 NTKLELLAKKTSE 377
E+ AK+ E
Sbjct: 13633 ----EIEAKRQEE 13641
Score = 64.7 bits (156), Expect = 2e-07
Identities = 117/652 (17%), Positives = 266/652 (40%), Gaps = 26/652 (3%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L+ + D+QK K +E + L+ + QSE+ SL+ E++ + Q +
Sbjct: 13950 LNKAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIK--- 14006
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVL---KQELSSARLQIESLEKELNQANEEV 1892
E +Q ++ + + S+ + E + + ++ + + + E+E++ +
Sbjct: 14007 ----TEMQQIEIKMQIQTRSVATQWETDVQIQQEGQEPIETTGHITKKSEEEISAKKTKQ 14062
Query: 1891 KVLSKFRYQVL-ELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVE- 1718
+++K + E++E D++++ QL K++I E E+ E
Sbjct: 14063 PIVTKLEDTLTSEVQEMRDMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEET 14122
Query: 1717 ----ERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKE 1550
R E +L +D++ N L++K E + +++QL ++ + K+
Sbjct: 14123 LKEKSRNEETLLQLLHDKDDLS-NTLDEKSKEIENITVTFKRNIAQLETTI----AMMKK 14177
Query: 1549 ESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTM 1370
+ + N L++ E REI+ T T E E + V + L+ E
Sbjct: 14178 DKENIENELLQLKQTEQ-EREIQRGTDDTSNER----ENYDEKVTYKTELEDSKEKKKPD 14232
Query: 1369 DHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENE-ECKSKQMEE 1193
+L T S + ++ T + K + ++ L +E E K K + E
Sbjct: 14233 RDSSLKLTDADSAKTDGEREAQT--LETKVQDVLQLTDYTTQDQEELHDEMENKMKIILE 14290
Query: 1192 YKMLQAELNNWL-SCMNAEMGKFLCL------CNSMVYLEGDILKYKEDLLLNH-GQLRA 1037
+ +L C +AE K + + NS+ ++ ++L ++ ++H Q++
Sbjct: 14291 LNEAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQE--IDHLAQIKT 14348
Query: 1036 EMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICS 857
EM ++I++ + +V + W+ I +GQ E I
Sbjct: 14349 EMQQIEIKM----------QIQTRSVATQ---WETDVQIQQGQ------EATETTGHITK 14389
Query: 856 LSEKIQQIEEREKVLLTQL-STKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDT 680
SE+ ++ ++ +T+L T +++Q + L E+++ K ++K D +E + +
Sbjct: 14390 KSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVARMKTIMKMEKDQLEQAKS 14449
Query: 679 NLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAH 500
++Q+ + F+++M+EA+ E + ++++
Sbjct: 14450 DIQTQMEE---------------------FERNMEEAMEEKSRNEEKLLQLTHDKEDLSN 14488
Query: 499 TSDKDEEVIKLQSQ-----VENLQSLVQMLK--QQNTKLELLAKKTSEMDPE 365
T DK + I+ ++ + L++ + ++K ++N + ELL K +E + E
Sbjct: 14489 TLDKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQERE 14540
Score = 63.9 bits (154), Expect = 3e-07
Identities = 125/676 (18%), Positives = 275/676 (40%), Gaps = 49/676 (7%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDL-------KETVKNLQSDLDIEQKLSTDRQSEIYSL-SAELER 2087
++ + D+Q E+ +D+ + T + L +++I QK++ +Q+ + + + ER
Sbjct: 6551 IEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINI-QKVNQQKQATAFQMEKTDFER 6609
Query: 2086 ITQSEQMSLKRLKEAEQ----TLLEAESERESLKAELEESISVLKQELSSARLQIESLEK 1919
I + K L + ++ T+ E + ERE+L+ E+ +IS + +++ + S E
Sbjct: 6610 IKTEIDQANKELADQQEKNKKTITEMQKERETLE-EMRANISKQVETITNENKSLSSRES 6668
Query: 1918 ELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEV 1739
EL + E++ Q E++E + ++ QL ++++I LQ+
Sbjct: 6669 ELAKLQEDI------LQQQQEMDELKNTIMMEMC-----------QLDQRQSDIDLLQKE 6711
Query: 1738 I---------EQKEVEERQRECMLAASERSNDINVNALEK------KLSAYEGKIRRLEN 1604
+ E VE + E + +D+ +EK +L E K +E
Sbjct: 6712 VDDLMDFTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNEEK-DLIEK 6770
Query: 1603 DVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSS 1424
+ LT ++D + + ++ N + I+N +E+ + K+++Q +EFS
Sbjct: 6771 ERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKELE-KMKISLQRKAIGFKEFSE 6829
Query: 1423 VVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXE 1244
K + ++ T D +G ++ Q+ + K E
Sbjct: 6830 KTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQT-----EKKRRKTYYTEDLFQE 6884
Query: 1243 CRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL 1064
+ +L+ K EE + E+ + +N E + S + +I K KE +
Sbjct: 6885 EKTDLQ------KTKEEINYDREEIYRQRTELNKEKETLKQMHTSNLKEIENIEKEKEKI 6938
Query: 1063 LLNHG---QLRAEMSSLKIELVEKNGFM----GYAVLDVENVQKELLIWKDRAMIAEGQS 905
Q+RAE+ + + ++ + M D+EN+Q E KD +
Sbjct: 6939 QRTWNELDQIRAELQNKQRDMDDTTNIMMKEKAELARDLENLQNE----KDELQKSRENI 6994
Query: 904 KAFQLELKHANMSIC-SLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISST 728
+ EL+ + +L+++ QQ E ++ K+ + + A++ + + +
Sbjct: 6995 QKLMKELQEERLKTSEALNKERQQFTE-------EIKLKNDSLDEIQAEIDRQKRALVTD 7047
Query: 727 KEML-KDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNI-----GFDQSMDEAV 566
KE++ K +D + D QS + I L + + +V I ++ DE +
Sbjct: 7048 KEIITKQMMDLQKTQDVRRQSDESDIARANLQRERESLDQLSVEILKQKQDLERERDELL 7107
Query: 565 SE---IAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQ-----VENLQSLVQMLKQQNT 410
+ + Q N++ + + TE+ + E++ K Q EN +L + L++ N
Sbjct: 7108 EQWRLVETQKMDNENVKQLKTELLDEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNL 7167
Query: 409 KLELLAKKTSEMDPEK 362
+ + + + ++++ K
Sbjct: 7168 QKQGIQDERAQLERMK 7183
Score = 63.9 bits (154), Expect = 3e-07
Identities = 130/706 (18%), Positives = 276/706 (39%), Gaps = 79/706 (11%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLD--------IEQKLSTDR------------- 2126
++ +R DI +EKN ++ +SDL+ +Q + +R
Sbjct: 12237 IEKIRQDIDREKN-------DLEKYRSDLEKQYEEMEICKQNIENERAELEIDLENIIIE 12289
Query: 2125 ----QSEIYSLSAELE---------------RITQSEQMSLKRLKEAEQTLLEAESERES 2003
Q + S+ +L+ R + + + K +E EQ E E++
Sbjct: 12290 TKSKQERLESIEVQLQEKNVQMGTILDELNKRQEELDAIKAKTQREKEQMGHTEELEKDE 12349
Query: 2002 LKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSAD 1823
L A L++ ++K+ + + Q E L+KE +Q L K + LE+E + L+++
Sbjct: 12350 LIAILQKREEIVKRHMEEIQNQREELQKEKDQFGNMQAELQKGQ---LEMEMHQLMLNSE 12406
Query: 1822 ----------LSKVHEDYSAALRQLFDKKNEITCLQEVI-EQKEVEERQRECMLAASERS 1676
L K E++ + L ++ E + L++++ E+K VEE M A +
Sbjct: 12407 RDELNGMRVNLEKQKEEFELMQQNLESRRPE-SLLEDILKEKKRVEE-----MAAQLSKE 12460
Query: 1675 NDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDL----LQE 1508
+ N + + + E KI+++E ++ + + + ++E + N + LQ
Sbjct: 12461 QEEFRNIMSETIKRME-KIKQIEGEIKTKQIEMACLEELKQKELDEQKNMRECENQELQM 12519
Query: 1507 IENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSN------TMDHDTLSST 1346
L +++ E + E + +++ LE +K L+ + HD +
Sbjct: 12520 RREELAKMKTEIDIERDEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQHDEIHGG 12579
Query: 1345 HQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELN 1166
E++ + D K + LE +E + +QM ++ E N
Sbjct: 12580 IDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQM----AVETEDN 12635
Query: 1165 NWLSCMNAEMGKFLCLC-------NSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELV 1007
+ + EM K + N + + ++ + K +L N L E + L ++
Sbjct: 12636 DSDKNLQDEMMKIEAILKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNKKVK 12695
Query: 1006 EKNGFMGYAVLDVENVQKELLIWKDRAM--IAEGQSKAFQLELKHANMSICSLSEKIQQI 833
E F + + E +K + +R M +AE K +K + ++ E+I++
Sbjct: 12696 ETEEFHMSKMEEREAERKTI----ERVMDEMAEEHEK-----IKKEREELVNMEEEIKKQ 12746
Query: 832 EEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQ-SHFNQ 656
+ + +++ K +++QH + E+ K+ L+D I + D + + S ++
Sbjct: 12747 RRVLEESMNEMTKKKSELQH-------ERSELYKQKQQLEDMIASESKRDVDTERSRQDK 12799
Query: 655 IQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEV 476
E +L + E ++++ Q K+ ED+ T + + E +
Sbjct: 12800 EDEQILKRE-----------------REEIADMKDQLL--KEKEDVETTKERINREKEHI 12840
Query: 475 IKLQSQVENL--------QSLVQMLKQQNTKLELLAKKTSEMDPEK 362
K+QSQ+ + Q L+ M + K L K ++ E+
Sbjct: 12841 EKMQSQLNDQKEEMDLENQKLLYMKTEIQVKTNALEKMMQDLQKER 12886
Score = 63.5 bits (153), Expect = 4e-07
Identities = 110/654 (16%), Positives = 277/654 (42%), Gaps = 44/654 (6%)
Frame = -2
Query: 2230 RLDIQKEKNISEDL-------KETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSE 2072
+ DI+ K I + L K ++ + +LDIE++ D Q + +EL+ +
Sbjct: 10209 KCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERI 10268
Query: 2071 QMSLKRLKEAEQTLLEAESERESLKAELE---ESISVLKQELSSARLQIESLEKEL-NQA 1904
+ + +K+ +TL E E+ E K E++ E LK++L + K+L NQ
Sbjct: 10269 RNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRLKEDLEKMSTDVNKQNKDLMNQR 10328
Query: 1903 N----EEVKVLSKFRYQVLELEEYSQQLS----ADLSKVHEDYSAALRQLFDKKNEITCL 1748
+ E ++ K++ ++E+ Q+S DL K + + L + K + +
Sbjct: 10329 DLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPK-EKGMKEDRKSLEETKANVIEM 10387
Query: 1747 QEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFS 1568
+ E +E+++ + + E +I V ++ Y+ +++++ ++ +D
Sbjct: 10388 KTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELYQ-----IKSELERVRSEID-- 10440
Query: 1567 AGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQL 1388
E K+++ ++++ + L +++ E Q+ E + ++ K +
Sbjct: 10441 -----HEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDI 10495
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKS 1208
E S + + E + Q + D + + + L+NE +
Sbjct: 10496 EKSKEIVEKLMVEVE----EQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERI 10551
Query: 1207 KQM-EEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEM 1031
K++ EE K + L + E + + + D+ K D+ L+ +
Sbjct: 10552 KKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQR 10611
Query: 1030 SSLKIELVEKNGFMGYAVLDVE------NVQKELL----IWKDRAMIAEGQSKAFQLELK 881
L+ E E N M ++ + Q+E L + ++R + E +++ +++ K
Sbjct: 10612 DLLEQEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTK 10671
Query: 880 HANMSICSLSEKIQQIEEREKVLL----TQLSTKDTDMQHLAAQLTLAQEEISSTKEMLK 713
I + EK ++ EE +V++ +L+ ++++ + +++ Q++++ K++++
Sbjct: 10672 AELQEI--MQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIE 10729
Query: 712 DFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFD-QSMDEAVSEIAVQTFPN 536
+++E + + + Q++E ++ ++ T D ++ E V ++ V+
Sbjct: 10730 QEKEDLEKMKSEIMTQRQQMEEE--RSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQ 10787
Query: 535 K-----DTEDINTEIAHTSDKDEEVI----KLQSQVENLQSLVQMLKQQNTKLE 401
+ E+++ E +D+ V+ KLQ++ E ++ + + +K++ L+
Sbjct: 10788 RKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLK 10841
>ref|XP_001582487.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121916722|gb|EAY21501.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 1794
Score = 102 bits (253), Expect = 9e-19
Identities = 140/686 (20%), Positives = 291/686 (42%), Gaps = 59/686 (8%)
Frame = -2
Query: 2212 EKNISEDLK---ETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEA 2042
EKNISE + E +K+L +L Q + + Q+EI SL E+++ +E+ +++K
Sbjct: 1041 EKNISEKSETYNEKIKSLTDELSTIQNKNENLQNEIKSLQ---EKLSNNEKNDNEKVKLY 1097
Query: 2041 EQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQV 1862
E+ L + E ++LK E+ + + + + QI+ + + L +A +V L
Sbjct: 1098 EEQLNSLKKENDNLKQEMSDIQKSDNETFENYQNQIKEMMQNLEEAENKVSTLQ------ 1151
Query: 1861 LELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI----TCLQEVI-----EQKEVEERQ 1709
E+ S +D KV Y A + Q+ +K E+ T ++++ E+KE+EE+
Sbjct: 1152 ---EQISMNEKSDSEKV-TSYEAKIAQMHQEKKELEKKFTAAKQIVSNNRQEKKEMEEKI 1207
Query: 1708 RECMLAASERSNDI-----NVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEES 1544
S++ ++ + +L K+++ E + +++ D+ Q ++ E+
Sbjct: 1208 NSLTKQVSDKDEELQKSKEEIESLNHKVTSNEAEKQKVAEDLQQKLSEIESLKQKLTEKE 1267
Query: 1543 TKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDH 1364
V + + IE+ ++I + KV I + + +E S + L+ K E D
Sbjct: 1268 NDVQKVTEQNKSIEDLKQQISEKEKV-ITDNQKTIENLSFELTELKQKKDDSE----KDK 1322
Query: 1363 DTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKM 1184
+ + + + + KA S +ND R+ +N++ +K +E K+
Sbjct: 1323 EIIQNLTKDLEKMKADLDSKQKEND---------EIRSRLNREIEDNKQALAKAVETAKI 1373
Query: 1183 LQAELNNWLSCM----NAEMGKFLCLCNSMVYLEGDILKYK-------EDLLLNHGQLRA 1037
L E M ++E K L + + LE + + ED +L
Sbjct: 1374 LSEENEKLTKQMEQVSSSETEKCQVLSSKISTLESRLQSSETRATSVLEDRNRLSSELLR 1433
Query: 1036 EMSSLKIELVEKNGF---MGYAVLDVE-NVQKELLIWKDRAMIAEGQSKAFQLELKHANM 869
MS LK EK+ + ++E N +++ ++ + + E + + + ++ +
Sbjct: 1434 TMSELKESKNEKDKITQEFNDKIKELESNSREQTANYEGKIKLLESEKSSLETKINEDQL 1493
Query: 868 SICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQ-----------------LTLAQEE 740
I +L + +Q + + V ++S D L Q LT E+
Sbjct: 1494 KISNLEKNVQNLSNKNSVSDNEVSKLKEDNSKLKNQISNFEVEIMQIKESNDLLTSQNEK 1553
Query: 739 ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSE 560
+ +K L+ ++++EA+ +L Q++ +N LE +S++E +S
Sbjct: 1554 LRESKNKLQQNVNDLEATKKDLTQKMAQMKCDSRENEINSLLET------KKSLEEKISV 1607
Query: 559 IAVQTFP-NKDTEDINTEI-AHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKK 386
+ Q KD D+ +I D ++++K + Q+ ++V ++++ +LE K+
Sbjct: 1608 LQNQIATILKDKSDLAEQIELKEIDIKDQMLKYKEQMSQNDNVVFEMRKEKIELENQIKE 1667
Query: 385 --------TSEMDPEKYFHFEELCQS 332
S+M+ EK EEL +S
Sbjct: 1668 IKYQNELNVSKMNQEK----EELTKS 1689
Score = 93.2 bits (230), Expect = 4e-16
Identities = 131/632 (20%), Positives = 284/632 (44%), Gaps = 14/632 (2%)
Frame = -2
Query: 2218 QKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAE 2039
+KEK EDL + +K L+++ +QKL+ D +S+I + + Q +K +
Sbjct: 515 EKEKQF-EDLSQKLKQLEAE---KQKLNDDYESKINEIQQNDNETFTNYQNQIKEMMINN 570
Query: 2038 QTLLEAESERESLKAELE-------ESISVLKQELSSARLQIESLEKELNQANEEVKVLS 1880
+ L ++E +SL+ ++ E + L+++L ++ I SL+++L + + ++ L
Sbjct: 571 ENL---QNENKSLQEKISLNEKSDNEKVLSLEEQLKESKNSISSLQEQLKSSQQTIENLE 627
Query: 1879 KFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQREC 1700
K + E S+ + + + ++ S + +NEI LQE + E + ++
Sbjct: 628 K------NISEKSETYNEKIKSLTDELSTIQNTNENLQNEIKSLQEKLSNNEKNDNEKIL 681
Query: 1699 MLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACD 1520
L +++ V ++KLS +E + ++ + +S + + S + KE K +
Sbjct: 682 NLEEQLKNSQNEVRIGQEKLSKFENEYDQMRSKLSLMEKELSTSQKM-KESLQKEKES-- 738
Query: 1519 LLQEIENFLREIRVETKVTIQEARHNVEEF-SSVVKHLEYLKSQLETSNTMDHDTLSSTH 1343
LQE + + E ++++E +N + ++ ++ + L+SQL T N + LS++
Sbjct: 739 -LQEKISLSEKSDNEKVLSLEEQLNNSKNMITNYEQNEKELQSQLSTLN----EELSTSK 793
Query: 1342 Q--GSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAEL 1169
+ ++E+K S+ GD K+ +N NE + Q E K+ E
Sbjct: 794 KMIETLEEKISNNEKNGDEKVKSYEEQLNSY------RNTINELQQITQSNEEKIKSLES 847
Query: 1168 NNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFM 989
N + + Y E + K+ + L ++ SLK E+
Sbjct: 848 QNKDLQEKISLSEKSESDKEKSY-EAQLNNLKQQAQNHISSLNQQIESLKQEISSIQQND 906
Query: 988 GYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLL 809
+ +N KE++I + + E QS ++ L S +EK+ +EE+
Sbjct: 907 NETFTNYQNQIKEMMI-NNENLQNEVQSLQEKISLNEK-----SDNEKVLSLEEQLNNSK 960
Query: 808 TQLSTKDTDMQHLAAQLTLAQEEISSTKEM---LKDFIDNMEASDTNLQSHFNQIQEMLL 638
++ + + + L +QL+ EE+S++K+M L++ I N E SD + +
Sbjct: 961 NMITNYEQNEKELQSQLSTLNEELSTSKKMIETLEEKISNNEKSDNEKVLSLEEQLKESK 1020
Query: 637 NQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQ 458
N + + + +++++ +SE + +T+ N+ + + E++ +K+E LQ++
Sbjct: 1021 NSISSLQEQLKSSQQTIENLEKNISEKS-ETY-NEKIKSLTDELSTIQNKNE---NLQNE 1075
Query: 457 VENLQ-SLVQMLKQQNTKLELLAKKTSEMDPE 365
+++LQ L K N K++L ++ + + E
Sbjct: 1076 IKSLQEKLSNNEKNDNEKVKLYEEQLNSLKKE 1107
Score = 83.2 bits (204), Expect = 4e-13
Identities = 138/667 (20%), Positives = 281/667 (42%), Gaps = 28/667 (4%)
Frame = -2
Query: 2242 LDAVRLDIQKEK----NISEDLKETVKNLQ----SDLD----IEQKLSTDRQSEIYSLSA 2099
+D ++ + Q EK N +LK ++KN + +DL+ I ++ S D +++I L
Sbjct: 315 IDDIKKNNQNEKENLINQINELKNSLKNKEISSENDLNEMKIIIEQTSKDYETKIQDLMT 374
Query: 2098 ELERITQSEQMSLKRLKEAEQ--------TLLEAESERESLKAELEESISVLKQELSSAR 1943
LE +Q ++LKE+E+ ++L+A ++ E K + + IS L +E +
Sbjct: 375 NLEENSQKLNEMSQKLKESEEKNQKLNEMSMLQASNDAE--KEKFIKEISNLTKENEKLQ 432
Query: 1942 LQIESLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKN 1763
+ EK + V K + E+ E ++ L ++ K+ E + +K+N
Sbjct: 433 TVLNENEKNRTENERLVAENQKLNSDLHEIGEVNKNLQTEIEKLTEIMKSEQN---NKEN 489
Query: 1762 EITCLQEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTL 1583
E+ L + QKE + + + L + + + L +KL E + ++L +D
Sbjct: 490 EMMSL---LSQKEEQVQALQVKLNQTNQEKEKQFEDLSQKLKQLEAEKQKLNDDYESKIN 546
Query: 1582 SVDFSAGVFKEESTKVSNAC-DLLQEIENFLREIR-VETKVTIQEARHNVEEFSSVVKHL 1409
+ + E T N +++ EN E + ++ K+++ E N V+
Sbjct: 547 EIQQNDN---ETFTNYQNQIKEMMINNENLQNENKSLQEKISLNEKSDN----EKVLSLE 599
Query: 1408 EYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNL 1229
E LK + +++ SS +K S+ S N+ K +NL
Sbjct: 600 EQLKESKNSISSLQEQLKSSQQTIENLEKNISEKSETYNE-KIKSLTDELSTIQNTNENL 658
Query: 1228 ENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHG 1049
+NE K ++E K+ E N+ +N E + N + + + K++ + +
Sbjct: 659 QNE---IKSLQE-KLSNNEKNDNEKILNLEE-QLKNSQNEVRIGQEKLSKFENE----YD 709
Query: 1048 QLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANM 869
Q+R+++S ++ EL E++QKE E + L K N
Sbjct: 710 QMRSKLSLMEKELSTSQKMK-------ESLQKE----------KESLQEKISLSEKSDNE 752
Query: 868 SICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEA 689
+ SL E++ K ++T + ++Q +QL+ EE+S++K+M++ + +
Sbjct: 753 KVLSLEEQLNN----SKNMITNYEQNEKELQ---SQLSTLNEELSTSKKMIETLEEKISN 805
Query: 688 SDTNLQSHFNQIQEML--LNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDIN 515
++ N +E L +N + T QS +E + + Q NKD ++
Sbjct: 806 NEKNGDEKVKSYEEQLNSYRNTINELQQIT------QSNEEKIKSLESQ---NKDLQE-K 855
Query: 514 TEIAHTSDKDEEVIKLQSQVENL----QSLVQMLKQQNTKLELLAKKTSEMDPEKYFHFE 347
++ S+ D+E ++Q+ NL Q+ + L QQ L+ + D E + +++
Sbjct: 856 ISLSEKSESDKEK-SYEAQLNNLKQQAQNHISSLNQQIESLKQEISSIQQNDNETFTNYQ 914
Query: 346 ELCQSLV 326
+ ++
Sbjct: 915 NQIKEMM 921
Score = 75.9 bits (185), Expect = 7e-11
Identities = 124/644 (19%), Positives = 266/644 (41%), Gaps = 44/644 (6%)
Frame = -2
Query: 2200 SEDLKETVKNLQ-SDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTLLE 2024
S+DL + N S+ + +Q+ + L E + QS+ ++RL + L +
Sbjct: 206 SQDLLDFSSNQNNSNFNQSSNQQNSQQNMLLDLFGEQQPANQSQNTDIQRLNDKISQLEK 265
Query: 2023 AESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEV--KVLSKFRYQVLELE 1850
+E++ EL I + + Q + LNQ +E+ +++K+ ++ +++
Sbjct: 266 ELAEKDDQINELANLIE------ENDKKQGTQQNQNLNQNDEDAIQSLVTKYEEEIDDIK 319
Query: 1849 EYSQQLSADL-SKVHEDYSAALRQLFDKKNEITCLQEVIEQ--KEVEERQRECMLAASER 1679
+ +Q +L ++++E ++ + +N++ ++ +IEQ K+ E + ++ M E
Sbjct: 320 KNNQNEKENLINQINELKNSLKNKEISSENDLNEMKIIIEQTSKDYETKIQDLMTNLEEN 379
Query: 1678 SNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIEN 1499
S +N + +KL E K ++L N++S L S D F +E + ++ + LQ + N
Sbjct: 380 SQKLN--EMSQKLKESEEKNQKL-NEMSMLQASNDAEKEKFIKEISNLTKENEKLQTVLN 436
Query: 1498 FLREIRVETKVTI---QEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSME 1328
+ R E + + Q+ ++ E V K+L+ T +
Sbjct: 437 ENEKNRTENERLVAENQKLNSDLHEIGEVNKNLQ-------------------TEIEKLT 477
Query: 1327 DKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCM 1148
+ S+ + +N+ + S++ E+ + LQ +LN
Sbjct: 478 EIMKSEQNNKENEMMSLL---------------------SQKEEQVQALQVKLNQ----T 512
Query: 1147 NAEMGK-FLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLD 971
N E K F L + LE + K +D E +I+ + F Y
Sbjct: 513 NQEKEKQFEDLSQKLKQLEAEKQKLNDDY---------ESKINEIQQNDNETFTNY---- 559
Query: 970 VENVQKELLIWKDRAMIAEGQSKAFQ----LELKHANMSICSLSEKIQQIEEREKVLLTQ 803
+N KE++I + + ++K+ Q L K N + SL E++++ + L Q
Sbjct: 560 -QNQIKEMMINNENL---QNENKSLQEKISLNEKSDNEKVLSLEEQLKESKNSISSLQEQ 615
Query: 802 LSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVN 623
L + +++L ++ E + + L D + ++ ++ NLQ+ +QE L N N
Sbjct: 616 LKSSQQTIENLEKNISEKSETYNEKIKSLTDELSTIQNTNENLQNEIKSLQEKLSNNEKN 675
Query: 622 ------------YPLEATVNIG------FDQSMDEAVSEIA-----------VQTFPNKD 530
+ V IG F+ D+ S+++ ++ K+
Sbjct: 676 DNEKILNLEEQLKNSQNEVRIGQEKLSKFENEYDQMRSKLSLMEKELSTSQKMKESLQKE 735
Query: 529 TEDINTEIAHTSDKD-EEVIKLQSQVENLQSLVQMLKQQNTKLE 401
E + +I+ + D E+V+ L+ Q+ N ++++ +Q +L+
Sbjct: 736 KESLQEKISLSEKSDNEKVLSLEEQLNNSKNMITNYEQNEKELQ 779
Score = 64.3 bits (155), Expect = 2e-07
Identities = 103/473 (21%), Positives = 207/473 (43%), Gaps = 5/473 (1%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
D +K+K I ++L + ++ +++DLD +QK + + +S L+ E+E Q+ L +
Sbjct: 1317 DSEKDKEIIQNLTKDLEKMKADLDSKQKENDEIRSR---LNREIEDNKQA-------LAK 1366
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQ 1865
A +T E E L ++E+ S ++ +I +LE L + +
Sbjct: 1367 AVETAKILSEENEKLTKQMEQVSSSETEKCQVLSSKISTLESRLQSSET----------R 1416
Query: 1864 VLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQ-KEVEERQRECMLAA 1688
+ E +LS++L + + L++ ++K++IT QE ++ KE+E RE
Sbjct: 1417 ATSVLEDRNRLSSELLRTMSE----LKESKNEKDKIT--QEFNDKIKELESNSRE----- 1465
Query: 1687 SERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQE 1508
+ + YEGKI+ LE++ S L ++ E+ K+SN L +
Sbjct: 1466 --------------QTANYEGKIKLLESEKSSLETKIN-------EDQLKISN---LEKN 1501
Query: 1507 IENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSME 1328
++N + V + + + + + + + + E Q++ SN D L+S ++ E
Sbjct: 1502 VQNLSNKNSVSDN-EVSKLKEDNSKLKNQISNFEVEIMQIKESN----DLLTSQNEKLRE 1556
Query: 1327 DKASSQSSTGDND-PKAXXXXXXXXXXXECRQNLENE--ECKSKQMEEYKMLQAELNNWL 1157
K Q + D + K + R+N N E K E+ +LQ ++ L
Sbjct: 1557 SKNKLQQNVNDLEATKKDLTQKMAQMKCDSRENEINSLLETKKSLEEKISVLQNQIATIL 1616
Query: 1156 SCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYA- 980
+++ + + L + ++ +LKYKE + N + EM KIEL + + Y
Sbjct: 1617 K-DKSDLAEQIEL--KEIDIKDQMLKYKEQMSQNDNVV-FEMRKEKIELENQIKEIKYQN 1672
Query: 979 VLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEERE 821
L+V + +E E +K+++ ++ + LS K+Q++ E +
Sbjct: 1673 ELNVSKMNQE----------KEELTKSYEEKILLYAKKVQQLSRKLQKVSENQ 1715
>ref|XP_001312904.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121894768|gb|EAX99974.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 3748
Score = 102 bits (253), Expect = 9e-19
Identities = 145/689 (21%), Positives = 291/689 (42%), Gaps = 78/689 (11%)
Frame = -2
Query: 2194 DLKETVKNLQSDLDIEQKLSTDRQS------EIYSLSAELERITQSEQ------------ 2069
DLK+ V +L +D + + D Q+ E+ L++++E I Q E+
Sbjct: 2419 DLKQEVIDLSKQIDEIKASNKDAQTKSDLLKELSQLNSQIENIIQEEEDKEEIRSHIEEI 2478
Query: 2068 MSLKRLKEAEQTLLEAES------ERESLKAELEESISVLKQELSSARLQIESLEKELNQ 1907
SL K++E+ E + +++SL +L+E I + K+E A+ I+ LE+E +
Sbjct: 2479 KSLLDNKQSEEDEKELDDLKKQLEDKQSLINKLKEDIKLTKEENEKAQKNIDDLEQEFDD 2538
Query: 1906 ANEEVKVLSKF----RYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEV 1739
N E + S+F + E+E Q +S ++ E +++ D E+ L++
Sbjct: 2539 LNNEYEEESQFDEERKLLETEIERLKQLISEKKTQNKEKTDKLFKEINDLTEELNSLEDD 2598
Query: 1738 IEQKEVE---ERQRECMLAASERSNDINVNA-LEKKLSAYEGKIRRL---ENDVSQLTLS 1580
E KE++ + E + + E SN L+K+L K++++ E + +L
Sbjct: 2599 SENKELQSQIDELNEQINSVKEESNPQQTKENLQKELDDLNNKLQQMIEDEEENEKLKEE 2658
Query: 1579 VDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYL 1400
+D K+ ++ N Q++++ + E++ + K Q+ E +S+ + L
Sbjct: 2659 IDALKEELKDNKSQEEN-----QQLKSQISELQEQIK---QKQNEISETENSLKSQISQL 2710
Query: 1399 KSQLETSNTMDHDTLSSTHQ--GSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLE 1226
+++L+ + D +S ++ S+++K ++Q D E
Sbjct: 2711 QNELKEKESERGDKSNSLYKEIDSLKEKINNQEIENKADSSQLSDLLKDLKKKLQELTEE 2770
Query: 1225 NEECKSKQMEEYKMLQAE----------LNNWLSCMNAEMGKFLCLCNSMVYLEGDILKY 1076
NE KSK EE + ++E LN L +N + K + LEG++
Sbjct: 2771 NETIKSKISEEKEKSKSEMAKLEEEKKSLNKELENVNDDEDKEM--------LEGEVSSL 2822
Query: 1075 KEDLLLN---HGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQS 905
KE L L + + + ++S K +L E+ + D E+++KE+ K+ + S
Sbjct: 2823 KETLNLKKQINEEQKQKLSQEKEKLTEELSQLN----DNEDLKKEIEQKKEELEKLKNDS 2878
Query: 904 KAFQLELKHANMSICSLSEK-----IQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEE 740
Q EL+ I SEK ++QIE+ +K ++S K+++ + + +++
Sbjct: 2879 SLLQ-ELQDLKKQIEEKSEKQNPELLKQIEDLKK----EISEKESENDLITGEKNTVEQQ 2933
Query: 739 ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSE 560
+ E K MEA+ + Q E+ + N + ++ Q + +++ E
Sbjct: 2934 YNKLVEQRKYLESTMEAAKKKVSDLRQQCDELSMKNN-QFRIDNEKEF---QEIKKSIEE 2989
Query: 559 IAVQ-------------------TFPNKDTEDINTEIAHTSDKDEEVIKLQSQ----VEN 449
I Q T + D ++ K+E ++K+ S+ V N
Sbjct: 2990 IKGQREQLAKKHNEDKRRAREYNTLARQKLTDAQQKLDAEKAKNENLLKMMSEQEKTVSN 3049
Query: 448 LQSLVQMLKQQNTKLELLAKKTSEMDPEK 362
L+ + L+Q+N +LE T + +K
Sbjct: 3050 LEKESEDLEQKNKELEQQMTSTGDFSQDK 3078
Score = 93.2 bits (230), Expect = 4e-16
Identities = 145/707 (20%), Positives = 312/707 (44%), Gaps = 79/707 (11%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSD-----LDIEQKLSTDRQSEIYSLSAELERITQSEQMSL 2060
D ++ ++ E++K + N QS+ LD +K D+QS I L +++ + + +
Sbjct: 2467 DKEEIRSHIEEIKSLLDNKQSEEDEKELDDLKKQLEDKQSLINKLKEDIKLTKEENEKAQ 2526
Query: 2059 KRLKEAEQTL------LEAESERESLKAELEESISVLKQELSSARLQ----IESLEKELN 1910
K + + EQ E ES+ + + LE I LKQ +S + Q + L KE+N
Sbjct: 2527 KNIDDLEQEFDDLNNEYEEESQFDEERKLLETEIERLKQLISEKKTQNKEKTDKLFKEIN 2586
Query: 1909 QANEEVKVL---SKFRYQVLELEEYSQQLSA--DLSKVHEDYSAALRQLFDKKNEITCLQ 1745
EE+ L S+ + +++E ++Q+++ + S + ++L D N+ LQ
Sbjct: 2587 DLTEELNSLEDDSENKELQSQIDELNEQINSVKEESNPQQTKENLQKELDDLNNK---LQ 2643
Query: 1744 EVIEQKEVEERQRECMLAASERSNDINV----NALEKKLSAYEGKIRRLENDVSQLTLSV 1577
++IE +E E+ +E + A E D L+ ++S + +I++ +N++S+ S+
Sbjct: 2644 QMIEDEEENEKLKEEIDALKEELKDNKSQEENQQLKSQISELQEQIKQKQNEISETENSL 2703
Query: 1576 -----DFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKH 1412
+ ++ES + + L +EI++ ++ K+ QE N + S +
Sbjct: 2704 KSQISQLQNELKEKESERGDKSNSLYKEIDS------LKEKINNQEI-ENKADSSQLSDL 2756
Query: 1411 LEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQN 1232
L+ LK +L+ T +++T+ S E K+ S+ + + + K+ E ++
Sbjct: 2757 LKDLKKKLQ-ELTEENETIKSKISEEKE-KSKSEMAKLEEEKKSLNKELENVNDDEDKEM 2814
Query: 1231 LENEECKSKQ-MEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDL--L 1061
LE E K+ + K + E LS ++ + L N L+ +I + KE+L L
Sbjct: 2815 LEGEVSSLKETLNLKKQINEEQKQKLSQEKEKLTEELSQLNDNEDLKKEIEQKKEELEKL 2874
Query: 1060 LNHGQLRAEMSSLKIELVEKNGFMGYAVL-DVENVQKEL--------LIWKDRAMIAE-- 914
N L E+ LK ++ EK+ +L +E+++KE+ LI ++ + +
Sbjct: 2875 KNDSSLLQELQDLKKQIEEKSEKQNPELLKQIEDLKKEISEKESENDLITGEKNTVEQQY 2934
Query: 913 ----GQSKAFQLELKHANMSICSLSEKIQQIE---------------------EREKVLL 809
Q K + ++ A + L ++ ++ E K
Sbjct: 2935 NKLVEQRKYLESTMEAAKKKVSDLRQQCDELSMKNNQFRIDNEKEFQEIKKSIEEIKGQR 2994
Query: 808 TQLSTKDTDMQHLAAQ--------LTLAQEEISSTK---EMLKDFIDNMEASDTNLQSHF 662
QL+ K + + A + LT AQ+++ + K E L + E + +NL+
Sbjct: 2995 EQLAKKHNEDKRRAREYNTLARQKLTDAQQKLDAEKAKNENLLKMMSEQEKTVSNLEKES 3054
Query: 661 NQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDE 482
+++ N+ + + +T + D+ + + +Q ++ ++ I ++
Sbjct: 3055 EDLEQK--NKELEQQMTSTGDFSQDKIEELRKKKEELQKLNDELSQKQKQNIEQSNSLQN 3112
Query: 481 EVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEKYFHFEEL 341
E + L +++E+L+S + +++++T++E ++ + EK E+L
Sbjct: 3113 EKVTLSNEIESLKSSTEAMEKESTEMEKKLEEDKGIISEKSKEKEDL 3159
Score = 92.0 bits (227), Expect = 1e-15
Identities = 139/690 (20%), Positives = 295/690 (42%), Gaps = 72/690 (10%)
Frame = -2
Query: 2218 QKEKNISE---DLKETVKNLQSDLDIEQKLSTDRQSEIYSL---------SAELERITQS 2075
QK+ ISE LK + LQ++L ++ D+ + +Y + E+E S
Sbjct: 2691 QKQNEISETENSLKSQISQLQNELKEKESERGDKSNSLYKEIDSLKEKINNQEIENKADS 2750
Query: 2074 EQMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEE 1895
Q+S LK+ ++ L E E E++K+++ E K E++ + +SL KEL N++
Sbjct: 2751 SQLS-DLLKDLKKKLQELTEENETIKSKISEEKEKSKSEMAKLEEEKKSLNKELENVNDD 2809
Query: 1894 ------------VKVLSKFRYQVLE-----LEEYSQQLSADLSKVH--EDYSAALRQLFD 1772
+K + Q+ E L + ++L+ +LS+++ ED + Q +
Sbjct: 2810 EDKEMLEGEVSSLKETLNLKKQINEEQKQKLSQEKEKLTEELSQLNDNEDLKKEIEQKKE 2869
Query: 1771 K----KNEITCLQEVIE-QKEVEERQRECMLAASERSNDINVNALEKKLS--AYEGKIRR 1613
+ KN+ + LQE+ + +K++EE+ + ++ D+ EK+ G+
Sbjct: 2870 ELEKLKNDSSLLQELQDLKKQIEEKSEKQNPELLKQIEDLKKEISEKESENDLITGEKNT 2929
Query: 1612 LENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEE 1433
+E ++L + + KVS+ E+ + R++ + QE + ++EE
Sbjct: 2930 VEQQYNKLVEQRKYLESTMEAAKKKVSDLRQQCDELSMKNNQFRIDNEKEFQEIKKSIEE 2989
Query: 1432 FSS-----VVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKA---------SSQSSTGD 1295
KH E K + NT+ L+ Q +KA S Q T
Sbjct: 2990 IKGQREQLAKKHNED-KRRAREYNTLARQKLTDAQQKLDAEKAKNENLLKMMSEQEKTVS 3048
Query: 1294 NDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLC 1115
N K E +Q + ++EE + + EL ++ + + +
Sbjct: 3049 NLEKESEDLEQKNKELE-QQMTSTGDFSQDKIEELRKKKEELQKLNDELSQKQKQNIEQS 3107
Query: 1114 NSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWK 935
NS+ + + E L + + E + ++ +L E G + + E+++K+ +
Sbjct: 3108 NSLQNEKVTLSNEIESLKSSTEAMEKESTEMEKKLEEDKGIISEKSKEKEDLEKKSKEQQ 3167
Query: 934 DRA-----MIAEGQSKAFQLELKHANM---------SICSLSEKIQQIEER-EKVLLTQL 800
+++ +AE Q KA ++ ++ ++ SI + + + +EE EK L
Sbjct: 3168 EKSDKLKQEVAELQEKAKKITTENTDLNDKITDLEISISNAERRKKDLEEEIEKSSAKSL 3227
Query: 799 STKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNY 620
K+ +++ +A + ++E+ K+ K I ++E+S + L+ ++E + N +
Sbjct: 3228 QEKEKELEEIAEK---KKKEVREMKKQHKQNIRSLESSISLLEQDIKSLEE-IQNSSKKS 3283
Query: 619 PLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQ-VENLQ 443
E Q +DE V+++ ++ F + EDI +D+D E+ K + + +E +
Sbjct: 3284 EQEGL------QLLDEKVADLKIKKF---ELEDI------IADRDSELKKWEKELLEKNK 3328
Query: 442 SLVQMLKQ----QNTKLELLAKKTSEMDPE 365
L ++ +Q + K++ + + ++D E
Sbjct: 3329 ELSEVNRQIRALKGDKIDQIKEDIKDIDEE 3358
Score = 85.1 bits (209), Expect = 1e-13
Identities = 136/682 (19%), Positives = 291/682 (42%), Gaps = 66/682 (9%)
Frame = -2
Query: 2212 EKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAE-------LERITQS-EQMSLK 2057
E+ + LK + ++++ +D + K + + + +I L++E LE+ + L
Sbjct: 1956 EQQQVDSLKSQILSVKAQIDDQNKKNEEMKKQIEKLTSEKSDAQNELEKAENKVDPDELV 2015
Query: 2056 RL-KEAEQTLLEAESER---ESLKAELEESISVLKQELSSARL--------QIESLEKEL 1913
RL +E E+ LEA+ ++ E +++ LEE +S K+ L + + QI+ ++ +
Sbjct: 2016 RLSEEIEELKLEADEKKKQNEEVRSSLEEELSKYKEILENLKSDNQSDIHNQIDQIKDRI 2075
Query: 1912 NQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIE 1733
N+ +E + ++ ++ E+ ++L +++K HE+ + Q DK N+ I+
Sbjct: 2076 NEKQQENEADNQ---KLQEIINNHKKLLENMNKEHEEIQKQIEQEVDKNNK------EID 2126
Query: 1732 QKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLEN----DVSQLTLSVD--- 1574
QK+ E + + L +++ N+ + L++++ +I +L+N ++ L +D
Sbjct: 2127 QKQKEINEVKEKLQQAKKENEDDKVELQRQIDNCGREIEKLQNAGDSEIDLLKQEIDKKE 2186
Query: 1573 ----------------FSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHN 1442
+ A + +E NA L EIEN ++I + E ++
Sbjct: 2187 KERQQATEQKQHEIEMYKAKLQHKEQENAVNAEKLHNEIENLKKKIDSQE----MEYKNY 2242
Query: 1441 VEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXX 1262
E + ++ L+ ++E N + + KA S ND +
Sbjct: 2243 NESLTKILDKLKVKLEEVEEENRNEDERAEEVENL----KAQIASKRKQNDAENEKLSQE 2298
Query: 1261 XXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCM-NAEMGKFLCLCNSMVYLEGDI 1085
E QNL+ ++ ++EE K +L +S + E K + E D
Sbjct: 2299 INKLKEELQNLQ----ENTEIEEMKQTVEDLKTQISVFGDPEQEKI------KLQKEIDE 2348
Query: 1084 LKYKEDLLLN----HGQLRAEMSSLK------IELVEKNGFMGYAVLDVENVQKELLIWK 935
L K + L + +LR ++ +LK +E+++ + E+ +++ L+ +
Sbjct: 2349 LTEKTEKLAEADDENDKLREQIENLKNVKSRDVEIIDLG--------EEEDGERQQLVEE 2400
Query: 934 DRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKV------LLTQLSTKDTDMQH 773
+ E + ++ + LS++I +I+ K LL +LS ++ +++
Sbjct: 2401 LNKLKEEYEQLQNTDDINDLKQEVIDLSKQIDEIKASNKDAQTKSDLLKELSQLNSQIEN 2460
Query: 772 LAAQLTLAQEEISSTKEMLKDFIDNMEASDT-----NLQSHFNQIQEMLLNQNVNYPLEA 608
+ Q +EEI S E +K +DN ++ + +L+ Q ++ + L
Sbjct: 2461 II-QEEEDKEEIRSHIEEIKSLLDNKQSEEDEKELDDLKKQLEDKQSLINKLKEDIKLTK 2519
Query: 607 TVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQM 428
N +++D+ E +D+N E S DEE L++++E L+ L+
Sbjct: 2520 EENEKAQKNIDDLEQEF----------DDLNNEYEEESQFDEERKLLETEIERLKQLISE 2569
Query: 427 LKQQN-TKLELLAKKTSEMDPE 365
K QN K + L K+ +++ E
Sbjct: 2570 KKTQNKEKTDKLFKEINDLTEE 2591
Score = 84.3 bits (207), Expect = 2e-13
Identities = 137/685 (20%), Positives = 291/685 (42%), Gaps = 91/685 (13%)
Frame = -2
Query: 2197 EDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTLL--- 2027
E + ++N+Q +++ ++ +++Q E+ L ELE+I +Q + E + +
Sbjct: 1203 ETSDQPLENIQKEIETTKQEISEKQKELDELKQELEQIKDEDQSKADEISEEIENIKTQI 1262
Query: 2026 --------EAESERESLKAELEESISVL------KQELSSARLQIESLEKEL-------- 1913
E E ++EL+E + L K E QIE +KE+
Sbjct: 1263 DEKNKKNEEIAKNNEEKQSELDEKLKELQDLEEIKDETEEINQQIEETQKEIETKKQQKE 1322
Query: 1912 --NQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEV 1739
N+ NEE+ L + Q+ +E+ ++L+ ++ KV D + QL N+I EV
Sbjct: 1323 NNNKLNEELDKLKQDLEQIENVEDNVEKLTEEIEKVKSDIDSK-HQL---NNDIKEANEV 1378
Query: 1738 IEQK-EVEERQRECMLAASERSNDI--NVNALEKKLSAYEGKIRRLENDVSQLTLSVDFS 1568
+E++ + + E + ++S++I + ++K++ + + L ++
Sbjct: 1379 VEEELNSLKEELEKIEPVEDKSDEIRKEIVKIQKEIETKKATNCGISESNELLNKELNDL 1438
Query: 1567 AGVFKEESTKVSNACDLLQEIENFLREI--RVETKVTIQEARHNV--------EEFSSVV 1418
+E + + ++ ++ EIEN + I + E Q+ N+ EEF +
Sbjct: 1439 KNQLEEIAEEKDDSEEIKAEIENLHKSIEEKKEHNANTQQNNENMKEELSKLQEEFDQIE 1498
Query: 1417 ----------KHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXX 1268
+E LKSQ+E NT ++D + + E+ + Q + D +
Sbjct: 1499 VVEDKAEEIHSEIEKLKSQIEEKNTTNND-IKEANDILNEELNNLQKQYDEIDVEEDKSE 1557
Query: 1267 XXXXXXXECRQNLE-----NEECKSKQ---MEEYKMLQAELNN--WLSCMNAEMGKFLCL 1118
+ ++ LE NE KS ++E + LQ EL+N +S + E K +
Sbjct: 1558 ELSQKVTDLQKLLEEKKSQNETIKSGNENILKELQSLQNELDNIEVVSSSSEEGEKKIEK 1617
Query: 1117 CNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVEN-VQKELLI 941
M+ D K E+ ++ +L ++ L+ EL E V D N +Q+++
Sbjct: 1618 LKQMI---SDKQKQNEETTKHNEELDNQIKDLENELNEI-----IPVKDKSNDLQQQIEE 1669
Query: 940 WKDRAMIAEGQSKAFQL------------ELKHANMSICSLSEKIQQIEEREKVLLTQLS 797
KD+ I + Q K + +LK +I + K ++I+++ + +++
Sbjct: 1670 IKDK--ITDKQKKNEECSQLNTALKEEYDQLKSEFDNIAVIESKAEEIQQKIDEIKSEID 1727
Query: 796 TKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYP 617
K + Q + L +E + ++ L+ I+ +E +LQ+ ++I E + ++ N
Sbjct: 1728 QKRKEYQDIKEGNDLLEEAYTEKQKELEQ-IEVVEDKTEDLQNLIDEITEQINSRKSNNL 1786
Query: 616 LEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHT--------------SDKD-- 485
N F++ + + E+ + ++E + EI T SD+D
Sbjct: 1787 ERQVSNETFEKQLGQLKQELNDLPQTDDNSESLKEEIEETKKKLAMMKDEYQRMSDEDKS 1846
Query: 484 --EEVIKLQSQVENLQSLVQMLKQQ 416
+E+I+++S++ +L++ +L+ +
Sbjct: 1847 LTDELIRVESELNDLENQKNVLENE 1871
Score = 82.4 bits (202), Expect = 8e-13
Identities = 129/694 (18%), Positives = 281/694 (40%), Gaps = 56/694 (8%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKN-LQSDLDIEQKLSTDRQSEIYSLSAEL-ERITQSEQ 2069
++ ++L+ ++K +E+++ +++ L +I + L +D QS+I++ ++ +RI + +Q
Sbjct: 2021 IEELKLEADEKKKQNEEVRSSLEEELSKYKEILENLKSDNQSDIHNQIDQIKDRINEKQQ 2080
Query: 2068 MSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVK 1889
+ ++ ++ + + E++ E EE ++QE+ +I+ +KE+N+ E+++
Sbjct: 2081 ENEADNQKLQEIINNHKKLLENMNKEHEEIQKQIEQEVDKNNKEIDQKQKEINEVKEKLQ 2140
Query: 1888 VLSKFRYQ-VLELEEYSQQLSADLSKVHEDYSAA---LRQLFDKKNEITCLQEVIEQKEV 1721
K +EL+ ++ K+ + L+Q DKK + Q+ EQK+
Sbjct: 2141 QAKKENEDDKVELQRQIDNCGREIEKLQNAGDSEIDLLKQEIDKKEKER--QQATEQKQH 2198
Query: 1720 EERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLE----NDVSQLTLSVDFSAGVFK 1553
E + L E+ N +N L ++ + KI E N LT +D +
Sbjct: 2199 EIEMYKAKLQHKEQENAVNAEKLHNEIENLKKKIDSQEMEYKNYNESLTKILDKLKVKLE 2258
Query: 1552 EESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNT 1373
E + N + +E+EN +I + K E +E + + + L+ L+ E
Sbjct: 2259 EVEEENRNEDERAEEVENLKAQIASKRKQNDAENEKLSQEINKLKEELQNLQENTEIEEM 2318
Query: 1372 M----DHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLEN-EECKS 1208
D T S ++K Q + K + R+ +EN + KS
Sbjct: 2319 KQTVEDLKTQISVFGDPEQEKIKLQKEIDELTEKTEKLAEADDENDKLREQIENLKNVKS 2378
Query: 1207 KQME----------EYKMLQAELNNW---------LSCMNAEMGKFLCLCNSM--VYLEG 1091
+ +E E + L ELN +N + + L + +
Sbjct: 2379 RDVEIIDLGEEEDGERQQLVEELNKLKEEYEQLQNTDDINDLKQEVIDLSKQIDEIKASN 2438
Query: 1090 DILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGY-----AVLD---VENVQKELLIWK 935
+ K DLL QL +++ ++ E +K + ++LD E +KEL K
Sbjct: 2439 KDAQTKSDLLKELSQLNSQIENIIQEEEDKEEIRSHIEEIKSLLDNKQSEEDEKELDDLK 2498
Query: 934 DRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTK---DTDMQHLAA 764
+ + + ++K + I +E+ L + + D + + L
Sbjct: 2499 KQLEDKQSLINKLKEDIKLTKEENEKAQKNIDDLEQEFDDLNNEYEEESQFDEERKLLET 2558
Query: 763 QLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQ 584
++ ++ IS K K+ D + +L N +++ N+ + ++
Sbjct: 2559 EIERLKQLISEKKTQNKEKTDKLFKEINDLTEELNSLEDDSENKELQSQID--------- 2609
Query: 583 SMDEAVSEIAVQTFPN-------KDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQML 425
++E ++ + ++ P K+ +D+N ++ + +EE KL+ +++ L+ ++
Sbjct: 2610 ELNEQINSVKEESNPQQTKENLQKELDDLNNKLQQMIEDEEENEKLKEEIDALKEELKDN 2669
Query: 424 KQQ--NTKLELLAKKTSEMDPEKYFHFEELCQSL 329
K Q N +L+ + E +K E SL
Sbjct: 2670 KSQEENQQLKSQISELQEQIKQKQNEISETENSL 2703
Score = 81.6 bits (200), Expect = 1e-12
Identities = 143/745 (19%), Positives = 298/745 (40%), Gaps = 48/745 (6%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
+IQKEK + + E +L+ E+ + Q E+ SL +L+ I + +++
Sbjct: 623 EIQKEKANKDKISEEKNKRDKELNDEK---SKLQDELDSL--QLDEIENENDQLFEEVED 677
Query: 2044 AEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQ 1865
+ + +A+ L ++ + I LKQ+ S + + LEK+ + ++E++ +SK +
Sbjct: 678 LKSKVDDAKI----LYNDMVDKIDDLKQQRSKVEQKYKDLEKQNKEKSDEIEKVSKEISE 733
Query: 1864 VLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVI-----EQKEVEERQREC 1700
+ E + Q + ++H+ A Q+ K E +QE + E + +E E
Sbjct: 734 LKEKLDNLNQFKDNTPELHQKVDAMNEQIVKKSQENEKIQEEMNKLNEELQHLENEMEEI 793
Query: 1699 MLAASERS------NDINVNALEKKLSAYE-----GKIRRLENDVSQLTLSVDFSAGVFK 1553
+ ER ++I EKK S E + END + ++ +
Sbjct: 794 EVVNDERETIQEKIDNIKQQIEEKKKSNEEIQDIMNLLIEAENDAQKELDDIEIVEAQSE 853
Query: 1552 EESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNT 1373
E ++ D LQ+ + E+ E+ + + K L+ L+++L+ +
Sbjct: 854 EIRQRIQTLQDNLQDRKKLNNEL--------------TEQNNKLQKELKDLQNELDQTEL 899
Query: 1372 MDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEE 1193
++ D+ S +K + N+ K+ QN N E K +EE
Sbjct: 900 VNDDSESL-------NKKLDEIKEQINERKS--------------QNENNTEQNEKLIEE 938
Query: 1192 YKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIE 1013
+ EL+ E +I++ K D +L+A++S L+ +
Sbjct: 939 IEKFAKELD-----------------------EIEIIEDKSD------KLQAQISELQKQ 969
Query: 1012 LVEKNGFMGYAVLDVENVQKELLIWK---DRAMIAEGQSKAFQLELKHANMSICSLSEKI 842
+ EK +++ EL I K D + S + E+++ N ++I
Sbjct: 970 IDEKQKNNEQTDKSNNDLEHELQITKQKLDSMSSVKNNSDYLKSEIENVN-------KEI 1022
Query: 841 QQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHF 662
++I + L +L K+ +++ + +I+ E LK+ ID++ T ++
Sbjct: 1023 EKIRDTNNKLKQELQDKNKELEEMT--------DIADNSEELKEKIDSVNEEITKRVANN 1074
Query: 661 NQIQEMLLN-----QNVNYPLEATVNI-----GFDQSMDEAVSEIAVQTFPNKDTEDINT 512
I E++ + +N L++ ++ +S+DE +++I+ + ++ +++N
Sbjct: 1075 TTIDELIRHLHEDLKNAEAKLQSIPHVDDNTDSLQKSLDEVLAQISQK---QRENDELND 1131
Query: 511 EIAHTSDKDEEVI--------------KLQSQVENLQSLVQMLKQQNTKLELLAKKTSEM 374
EI+ + EE ++ S++E ++S ++ K+ N K+ KK +E
Sbjct: 1132 EISRLIQEKEEKTDELNNMETIPDKREEISSEIETVKSQIEEKKKNNEKIAEENKKLAE- 1190
Query: 373 DPEKYFHFEELCQSLVXXXXXXXXXXXXXXXKNQVLVKQVKEMQVTLQSESPMEGETDSI 194
E L Q+L +Q L KE++ T Q S + E D +
Sbjct: 1191 ------ELENLRQTL-----------SKMETSDQPLENIQKEIETTKQEISEKQKELDEL 1233
Query: 193 SENA-----IGSQPAGKLSTELHNV 134
+ A ++S E+ N+
Sbjct: 1234 KQELEQIKDEDQSKADEISEEIENI 1258
Score = 77.0 bits (188), Expect = 3e-11
Identities = 161/803 (20%), Positives = 322/803 (40%), Gaps = 101/803 (12%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQS-------EIYSLSAELERI---TQS 2075
+I E++ SE+L + V +LQ L+ ++ + +S E+ SL EL+ I + S
Sbjct: 1548 EIDVEEDKSEELSQKVTDLQKLLEEKKSQNETIKSGNENILKELQSLQNELDNIEVVSSS 1607
Query: 2074 EQMSLKRLKEAEQTLLEAESERESL---KAELEESISVLKQELSSARLQIESLEKELNQA 1904
+ K++++ +Q + + + + E EL+ I L+ EL+ + ++ +L Q
Sbjct: 1608 SEEGEKKIEKLKQMISDKQKQNEETTKHNEELDNQIKDLENELNEI-IPVKDKSNDLQQQ 1666
Query: 1903 NEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQK- 1727
EE+K K + + EE SQ +A + E+Y L+ FD I E I+QK
Sbjct: 1667 IEEIK--DKITDKQKKNEECSQLNTA----LKEEYDQ-LKSEFDNIAVIESKAEEIQQKI 1719
Query: 1726 -----EVEERQRECMLAASERSNDINVNALEKK------LSAYEGKIRRLENDVSQLTLS 1580
E++++++E + ND+ A +K + E K L+N + ++T
Sbjct: 1720 DEIKSEIDQKRKEYQ--DIKEGNDLLEEAYTEKQKELEQIEVVEDKTEDLQNLIDEITEQ 1777
Query: 1579 VDF-----------------SAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEA 1451
++ G K+E + D + ++ + E + + + E
Sbjct: 1778 INSRKSNNLERQVSNETFEKQLGQLKQELNDLPQTDDNSESLKEEIEETKKKLAMMKDEY 1837
Query: 1450 RHNVEEFSSVVKHLEYLKSQLET----SNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPK 1283
+ +E S+ L ++S+L N ++++T+ + D + K
Sbjct: 1838 QRMSDEDKSLTDELIRVESELNDLENQKNVLENETIVKAEKKMQNDNTIMDLRNKIDTLK 1897
Query: 1282 AXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMV 1103
A +Q + +E K +EY+ L+ + + +S E+ +S+
Sbjct: 1898 AQL-----------QQQEKPQEDIEKLKKEYQELKFQFDAKVSQNKEEVSHSENELHSLK 1946
Query: 1102 YLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAM 923
+ I K ++ + L++++ S+K ++ ++N +N + + I K +
Sbjct: 1947 EMYDKIEKVEQQQV---DSLKSQILSVKAQIDDQNK---------KNEEMKKQIEKLTSE 1994
Query: 922 IAEGQSKAFQLELKHANMSICSLSEKIQQI-----------EEREKVLLTQLSTKDTDMQ 776
++ Q++ + E K + LSE+I+++ EE L +LS ++
Sbjct: 1995 KSDAQNELEKAENKVDPDELVRLSEEIEELKLEADEKKKQNEEVRSSLEEELSKYKEILE 2054
Query: 775 HLAAQLTLAQEEISSTKEMLKDFIDNM----EASDTNLQSHFNQIQEMLLNQN-----VN 623
+L + Q +I + + +KD I+ EA + LQ N +++L N N +
Sbjct: 2055 NLKSD---NQSDIHNQIDQIKDRINEKQQENEADNQKLQEIINNHKKLLENMNKEHEEIQ 2111
Query: 622 YPLEATV---NIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDK-DEEVIKLQ--- 464
+E V N DQ E K+ ED E+ D E+ KLQ
Sbjct: 2112 KQIEQEVDKNNKEIDQKQKEINEVKEKLQQAKKENEDDKVELQRQIDNCGREIEKLQNAG 2171
Query: 463 -SQVENLQSLV--------QMLKQQNTKLELLAKKTSEMDPEKYFHFEELCQSLVXXXXX 311
S+++ L+ + Q +Q+ ++E+ K + E + E+L +
Sbjct: 2172 DSEIDLLKQEIDKKEKERQQATEQKQHEIEMYKAKLQHKEQENAVNAEKLHNEIENLKKK 2231
Query: 310 XXXXXXXXXXKNQVLVKQVKEMQVTLQ-------SESPMEGETDSI------------SE 188
N+ L K + +++V L+ +E E +++ +E
Sbjct: 2232 IDSQEMEYKNYNESLTKILDKLKVKLEEVEEENRNEDERAEEVENLKAQIASKRKQNDAE 2291
Query: 187 NAIGSQPAGKLSTELHNVHGNTE 119
N SQ KL EL N+ NTE
Sbjct: 2292 NEKLSQEINKLKEELQNLQENTE 2314
Score = 74.7 bits (182), Expect = 2e-10
Identities = 141/695 (20%), Positives = 277/695 (39%), Gaps = 61/695 (8%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSE--Q 2069
L+ + QKE E +++ ++LQ+ +D + R+S LER +E +
Sbjct: 1743 LEEAYTEKQKELEQIEVVEDKTEDLQNLIDEITEQINSRKSN------NLERQVSNETFE 1796
Query: 2068 MSLKRLKEAEQTLLEAESERESLKAELEES---ISVLKQE----------LSSARLQIES 1928
L +LK+ L + + ESLK E+EE+ ++++K E L+ +++ES
Sbjct: 1797 KQLGQLKQELNDLPQTDDNSESLKEEIEETKKKLAMMKDEYQRMSDEDKSLTDELIRVES 1856
Query: 1927 ----LEKELNQANEEVKVLSKFRYQ----VLELEEYSQQLSA----------DLSKVHED 1802
LE + N E V ++ + Q +++L L A D+ K+ ++
Sbjct: 1857 ELNDLENQKNVLENETIVKAEKKMQNDNTIMDLRNKIDTLKAQLQQQEKPQEDIEKLKKE 1916
Query: 1801 YSAALRQLFDKK------------NEITCLQEVIEQKEVEERQRECMLAASERSNDINVN 1658
Y L+ FD K NE+ L+E+ ++ E E+Q+ L + S ++
Sbjct: 1917 YQ-ELKFQFDAKVSQNKEEVSHSENELHSLKEMYDKIEKVEQQQVDSLKSQILSVKAQID 1975
Query: 1657 ALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRV 1478
KK + +I +L ++ S ++ + E L +EIE E
Sbjct: 1976 DQNKKNEEMKKQIEKLTSEKSDAQNELEKA-----ENKVDPDELVRLSEEIEELKLEAD- 2029
Query: 1477 ETKVTIQEARHNVEEFSSVVKH-LEYLKS--QLETSNTMDHDTLSSTHQGSMEDKASSQS 1307
E K +E R ++EE S K LE LKS Q + N +D ++D+ + +
Sbjct: 2030 EKKKQNEEVRSSLEEELSKYKEILENLKSDNQSDIHNQID----------QIKDRINEKQ 2079
Query: 1306 STGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKF 1127
+ D + N E+EE + + +E E++ +N K
Sbjct: 2080 QENEADNQKLQEIINNHKKLLENMNKEHEEIQKQIEQEVDKNNKEIDQKQKEINEVKEK- 2138
Query: 1126 LCLCNSMVYLEGDILKYKEDL---------LLNHGQLRAEMSSLKIELVEKNGFMGYAVL 974
L + E D ++ + + L N G ++ +I+ EK
Sbjct: 2139 --LQQAKKENEDDKVELQRQIDNCGREIEKLQNAGDSEIDLLKQEIDKKEKERQQA---- 2192
Query: 973 DVENVQKELLIWKDRAMIAEGQ----SKAFQLELKHANMSICSLSEKIQQIEEREKVLLT 806
E Q E+ ++K + E + ++ E+++ I S + + E +L
Sbjct: 2193 -TEQKQHEIEMYKAKLQHKEQENAVNAEKLHNEIENLKKKIDSQEMEYKNYNESLTKILD 2251
Query: 805 QLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNV 626
+L K +++ EE+ + K + +A + L N+++E L N
Sbjct: 2252 KLKVKLEEVEEENRNEDERAEEVENLKAQIASKRKQNDAENEKLSQEINKLKEELQNLQE 2311
Query: 625 NYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIKLQSQVENL 446
N +E Q++++ ++I+V P ++ + EI ++K E++ + + + L
Sbjct: 2312 NTEIEE-----MKQTVEDLKTQISVFGDPEQEKIKLQKEIDELTEKTEKLAEADDENDKL 2366
Query: 445 QSLVQMLKQQNTKLELLAKKTSEMDPEKYFHFEEL 341
+ ++ LK ++ + E D E+ EEL
Sbjct: 2367 REQIENLKNVKSRDVEIIDLGEEEDGERQQLVEEL 2401
Score = 72.8 bits (177), Expect = 6e-10
Identities = 129/715 (18%), Positives = 291/715 (40%), Gaps = 107/715 (14%)
Frame = -2
Query: 2224 DIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSE-------QM 2066
+I+ + E ++E + N++ ++ E+K S + +I +L E E Q E +
Sbjct: 792 EIEVVNDERETIQEKIDNIKQQIE-EKKKSNEEIQDIMNLLIEAENDAQKELDDIEIVEA 850
Query: 2065 SLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKV 1886
+ +++ QTL + +R+ L EL E + L++EL + +++ E + + K
Sbjct: 851 QSEEIRQRIQTLQDNLQDRKKLNNELTEQNNKLQKELKDLQNELDQTELVNDDSESLNKK 910
Query: 1885 LSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQL-----FDKKNEITCLQEVIEQKEV 1721
L + + Q+ E + ++ + K+ E+ ++L + K++ Q QK++
Sbjct: 911 LDEIKEQINERKSQNENNTEQNEKLIEEIEKFAKELDEIEIIEDKSDKLQAQISELQKQI 970
Query: 1720 EERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEEST 1541
+E+Q+ + D + N LE +L + K+ + SV ++ K E
Sbjct: 971 DEKQK------NNEQTDKSNNDLEHELQITKQKLDSMS--------SVKNNSDYLKSEIE 1016
Query: 1540 KVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLET------- 1382
V+ + +++ N L++ +Q+ +EE + + + E LK ++++
Sbjct: 1017 NVNKEIEKIRDTNNKLKQ-------ELQDKNKELEEMTDIADNSEELKEKIDSVNEEITK 1069
Query: 1381 ---SNTMDHDTLSSTHQGSMEDKASSQSSTG-DNDPKAXXXXXXXXXXXECRQNLENEEC 1214
+NT + + H+ +A QS D++ + ++ EN+E
Sbjct: 1070 RVANNTTIDELIRHLHEDLKNAEAKLQSIPHVDDNTDSLQKSLDEVLAQISQKQRENDEL 1129
Query: 1213 K---SKQMEEYKMLQAELNNW--LSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHG 1049
S+ ++E + ELNN + E+ + S + + K E + +
Sbjct: 1130 NDEISRLIQEKEEKTDELNNMETIPDKREEISSEIETVKSQIE---EKKKNNEKIAEENK 1186
Query: 1048 QLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRA----------------MIA 917
+L E+ +L+ L + M + +EN+QKE+ K +
Sbjct: 1187 KLAEELENLRQTLSK----METSDQPLENIQKEIETTKQEISEKQKELDELKQELEQIKD 1242
Query: 916 EGQSKAFQL--ELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAA------- 764
E QSKA ++ E+++ I ++K ++I + + ++L K ++Q L
Sbjct: 1243 EDQSKADEISEEIENIKTQIDEKNKKNEEIAKNNEEKQSELDEKLKELQDLEEIKDETEE 1302
Query: 763 ---QLTLAQEEISSTKEM-------------LKDFIDNMEASDTNLQSHFNQIQEML--- 641
Q+ Q+EI + K+ LK ++ +E + N++ +I+++
Sbjct: 1303 INQQIEETQKEIETKKQQKENNNKLNEELDKLKQDLEQIENVEDNVEKLTEEIEKVKSDI 1362
Query: 640 -----LNQNV---NYPLEATVNI---------GFDQSMDEAVSEIA-----VQT------ 545
LN ++ N +E +N + DE EI ++T
Sbjct: 1363 DSKHQLNNDIKEANEVVEEELNSLKEELEKIEPVEDKSDEIRKEIVKIQKEIETKKATNC 1422
Query: 544 -------FPNKDTEDINTEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLE 401
NK+ D+ ++ +++ ++ ++++++ENL ++ K+ N +
Sbjct: 1423 GISESNELLNKELNDLKNQLEEIAEEKDDSEEIKAEIENLHKSIEEKKEHNANTQ 1477
Score = 67.4 bits (163), Expect = 3e-08
Identities = 143/750 (19%), Positives = 299/750 (39%), Gaps = 111/750 (14%)
Frame = -2
Query: 2245 TLDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQM 2066
T D+++ +I K + E + KN + +D+ ++L+ +L R Q Q
Sbjct: 13 TADSIK-NISNTKKLQEICLQLYKNRHNLIDVNKQLAQ-----------QLARAQQRSQE 60
Query: 2065 SLKRLKEAEQTLLEAESERESLKAELEE----SISVLKQ--ELSSARLQIESLEKELNQA 1904
+ LKE Q ++E E + ESL+ E +E +IS + + S +S E E+ +
Sbjct: 61 AYNELKEQSQRMIELEHQNESLEYENKELKAKTISFVGEFPNTSGINQADDSNETEI-KI 119
Query: 1903 NEEVKVLSKFRYQVLELEEYSQQLSADLSK--------------VHEDYSAALRQLFDKK 1766
+ ++ ++K R + +LE+ +++L + + E SA L + ++
Sbjct: 120 RKLMRTINKQRRDIADLEQKNKELQEAATNGPLMKLPASEGGPGLDETKSALLIKQLYRE 179
Query: 1765 NEITCLQEVIEQKEVEERQREC--MLAASERSNDINVNAL------EKKLSAY------- 1631
N + +Q +K+++++ E + AA++ SN ++ L E KLS
Sbjct: 180 NARSKVQMDSLRKQLQDKDEEIKNLKAATDLSNS-RISELSGIIEGESKLSELKTPPSSP 238
Query: 1630 ------------EGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLRE 1487
+ ++++L++ + Q ++ G + + ++ DL+ E L+E
Sbjct: 239 SYRNFIDRGNYKDRRMKQLKDQLDQTETEIENEEGKTENLNYSLNEMIDLVAERRRALQE 298
Query: 1486 IR-------VETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSME 1328
+R + K I + + +KHL+ + + D ++T E
Sbjct: 299 LRNSQGKDEEKLKKQIAKVESEKTKIEDEIKHLQE-DEEPQIKKLKDRLDETTTKTQIAE 357
Query: 1327 DKASSQSSTGDNDPKAXXXXXXXXXXXECRQNL-ENEECKSKQMEEYKMLQAELNNWLSC 1151
K T ++ + RQNL E + + E +NN +
Sbjct: 358 KKLGEMRKTIEDSRQKLAQR---------RQNLIERRKELTNDAENTNTELQSINNQIQE 408
Query: 1150 MNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLD 971
+++E K L N ++ D K K L Q + +++ LK + E+ +
Sbjct: 409 IDSEFNKLNGLVNK---VQSDHSKKKSALQEQLAQKQKDLNDLKRKQAEEKASREAEIAK 465
Query: 970 V-ENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKI------------QQIE 830
+ + +QK + + D + + Q+ + E+ A + L ++ Q++
Sbjct: 466 INDQLQKTMKEYND---LNQPQNVDLKNEIDQATKDLKELESRVNKKREELFGKNNQRVA 522
Query: 829 EREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHF---- 662
E K L QL +K +M +L A++E + K LK I+++ + L+
Sbjct: 523 ELNK-LNEQLKSKMDEMVKADQELQSAKDEHEAKKNELKAEIESVSDEISKLKDELEVIP 581
Query: 661 --------NQIQEMLLNQNV--------NYPLEATVNIGFDQSMDEAVSEIAVQTFPNKD 530
+Q+ E+L + N L +++ + D+ E ++ + NK
Sbjct: 582 DFEVDDLKDQLNELLKEKEELEKEKIKNNDELNSSIIMLKDEIQKEKANKDKISEEKNKR 641
Query: 529 TEDINTEIAHTSDK----------------DEEVIKLQSQVENLQSL-------VQMLKQ 419
+++N E + D+ EEV L+S+V++ + L + LKQ
Sbjct: 642 DKELNDEKSKLQDELDSLQLDEIENENDQLFEEVEDLKSKVDDAKILYNDMVDKIDDLKQ 701
Query: 418 QNTKLELLAKKTSEMDPEKYFHFEELCQSL 329
Q +K+E K + + EK E++ + +
Sbjct: 702 QRSKVEQKYKDLEKQNKEKSDEIEKVSKEI 731
Score = 63.9 bits (154), Expect = 3e-07
Identities = 111/657 (16%), Positives = 269/657 (40%), Gaps = 43/657 (6%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMS 2063
L A ++QK+ + + E +DL+ E +++ + + S+ + + +
Sbjct: 959 LQAQISELQKQIDEKQKNNEQTDKSNNDLEHELQITKQKLDSMSSVKNNSDYLKSEIENV 1018
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISV------LKQELSSARLQI-------ESLE 1922
K +++ T + + E + ELEE + LK+++ S +I +++
Sbjct: 1019 NKEIEKIRDTNNKLKQELQDKNKELEEMTDIADNSEELKEKIDSVNEEITKRVANNTTID 1078
Query: 1921 KELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQE 1742
+ + +E++K + +++ + L L +V S R+ + +EI+
Sbjct: 1079 ELIRHLHEDLKNAEAKLQSIPHVDDNTDSLQKSLDEVLAQISQKQRENDELNDEIS---R 1135
Query: 1741 VIEQKEVEERQRECMLAASERSNDI-NVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSA 1565
+I++KE E+++++ N+ + K +I +++ + + + + A
Sbjct: 1136 LIQEKE-------------EKTDELNNMETIPDKREEISSEIETVKSQIEEKKKNNEKIA 1182
Query: 1564 GVFKEESTKVSNACDLLQEIENF---LREIRVETKVTIQEARHNVEEFSSVVKHLEYLKS 1394
K+ + ++ N L ++E L I+ E + T QE +E + + LE +K
Sbjct: 1183 EENKKLAEELENLRQTLSKMETSDQPLENIQKEIETTKQEISEKQKELDELKQELEQIKD 1242
Query: 1393 QLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEEC 1214
+ ++ + + + E ++ +N+ K + + + E
Sbjct: 1243 EDQSKADEISEEIENIKTQIDEKNKKNEEIAKNNEEKQSELDEKLKELQDLEEIKDETEE 1302
Query: 1213 KSKQME------EYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNH 1052
++Q+E E K Q E NN L N E+ K + +E ++ K E++
Sbjct: 1303 INQQIEETQKEIETKKQQKENNNKL---NEELDKLKQDLEQIENVEDNVEKLTEEI---- 1355
Query: 1051 GQLRAEMSS---LKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELK 881
++++++ S L ++ E N + + ++ +++ +D++ + Q E++
Sbjct: 1356 EKVKSDIDSKHQLNNDIKEANEVVEEELNSLKEELEKIEPVEDKSDEIRKEIVKIQKEIE 1415
Query: 880 HANMSICSLSEKIQQIEEREKVL---LTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKD 710
+ C +SE + + + L L +++ + D + + A++ E + + E K+
Sbjct: 1416 TKKATNCGISESNELLNKELNDLKNQLEEIAEEKDDSEEIKAEI----ENLHKSIEEKKE 1471
Query: 709 FIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKD 530
N + ++ N++ +++QE V ++ +++ S+I + N D
Sbjct: 1472 HNANTQQNNENMKEELSKLQEEFDQIEVVEDKAEEIH----SEIEKLKSQIEEKNTTNND 1527
Query: 529 TEDIN--------------TEIAHTSDKDEEVIKLQSQVENLQSLVQMLKQQNTKLE 401
++ N EI DK EE L +V +LQ L++ K QN ++
Sbjct: 1528 IKEANDILNEELNNLQKQYDEIDVEEDKSEE---LSQKVTDLQKLLEEKKSQNETIK 1581
Score = 59.3 bits (142), Expect = 7e-06
Identities = 73/359 (20%), Positives = 159/359 (44%), Gaps = 45/359 (12%)
Frame = -2
Query: 2230 RLDIQKEKN-----ISEDLKETVKNLQSDL-DIEQK-------------LSTDRQSEIYS 2108
+LD +K KN + + ++TV NL+ + D+EQK S D+ E+
Sbjct: 3025 KLDAEKAKNENLLKMMSEQEKTVSNLEKESEDLEQKNKELEQQMTSTGDFSQDKIEELRK 3084
Query: 2107 LSAELER----ITQSEQMSLKRLKEAEQTLLEAESERESLKA----------ELEESISV 1970
EL++ ++Q ++ ++++ + + +E ESLK+ E+E+ +
Sbjct: 3085 KKEELQKLNDELSQKQKQNIEQSNSLQNEKVTLSNEIESLKSSTEAMEKESTEMEKKLEE 3144
Query: 1969 LKQELSSARLQIESLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAA 1790
K +S + E LEK ++ E+ + K + +V EL+E +++++ + + +++ +
Sbjct: 3145 DKGIISEKSKEKEDLEK---KSKEQQEKSDKLKQEVAELQEKAKKITTENTDLNDKITDL 3201
Query: 1789 LRQLFDKKNEITCLQEVIEQ---KEVEERQRECMLAASERSNDI---------NVNALEK 1646
+ + + L+E IE+ K ++E+++E A ++ ++ N+ +LE
Sbjct: 3202 EISISNAERRKKDLEEEIEKSSAKSLQEKEKELEEIAEKKKKEVREMKKQHKQNIRSLES 3261
Query: 1645 KLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKV 1466
+S E I+ LE + S + E KV++ E+E+ + + E K
Sbjct: 3262 SISLLEQDIKSLEEIQNSSKKSEQEGLQLLDE---KVADLKIKKFELEDIIADRDSELKK 3318
Query: 1465 TIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDND 1289
+E +E S V + + LK + + + D + + K + ++ DND
Sbjct: 3319 WEKELLEKNKELSEVNRQIRALKG--DKIDQIKEDIKDIDEEIESKKKKLNLNTVEDND 3375
>ref|XP_001318285.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121901040|gb|EAY06062.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 2416
Score = 100 bits (250), Expect = 2e-18
Identities = 142/677 (20%), Positives = 296/677 (43%), Gaps = 64/677 (9%)
Frame = -2
Query: 2203 ISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTLLE 2024
+ E KE + + + ++++KL + SE E+E +T + K L E ++ L +
Sbjct: 749 VEELAKENDELSKENEELKEKLKDIKSSE------EIEELTNQIEELEKELNEKKEQLEQ 802
Query: 2023 AESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSK----------- 1877
E+E E+EE S +EL +IE L+ E+ + N+E+K L++
Sbjct: 803 TENELTQQIEEIEEEKS---EELKKKNEEIERLQNEIEELNKEIKSLTEEIDDLQEKLEN 859
Query: 1876 FRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVIEQKEVEERQRECM 1697
+ ++ EL+EY+++ + + ++ LR + K + + ++E KE E Q+ +
Sbjct: 860 AKKEIQELQEYAEKSQENDKQTIDELKEKLRLANETKVTDSDTKVLVESKEAAE-QKVLL 918
Query: 1696 LAASERSNDINVNAL--------EKKLS--AYEGKIRRLENDVSQLTLSVDFSAGVFKEE 1547
L I + L E+K+S E +I LE+++S+L +D + ++
Sbjct: 919 LEKEISDLKIEIEDLKSVIDEENEQKVSNTEAENRIHELESEISELKKELDQNNN--QQN 976
Query: 1546 STKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMD 1367
K+ ++++++ + E E KV+ EA + + E S + LK +L+ +N
Sbjct: 977 DEKIEKLQKEIEDLKSVIDE-ENEQKVSNTEAENRIHELESEISE---LKKELDQNNNQQ 1032
Query: 1366 HDTLSSTHQGSMED-KASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEY 1190
+D Q +ED K +SS +N+ + +QNLE++ ++ +
Sbjct: 1033 NDEKIEKLQKEIEDLKNELESSKAENEELQNEFEKEIDQISQEKQNLESQIKYLQEKGDK 1092
Query: 1189 KMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIEL 1010
+ +LN + + A++ ++ + DI +YK ++ L+ E+S+++
Sbjct: 1093 SEIIDKLNQTIEELRAKV--------EHMFTQEDIDEYKSEI----ENLKQELSNIE--- 1137
Query: 1009 VEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQIE 830
+ D E + EL +++ E + + + + I +L E I +E
Sbjct: 1138 -KSKQISEEKSQDYEEIVHEL---ENKLEAKETELSKLKSDFEQQTREIETLKENITNLE 1193
Query: 829 EREKVLLTQLSTKDTD-MQHLAAQLT----LAQEEISSTKEMLKDF---IDNMEASDTNL 674
++ ++ D + + HL Q++ Q++I S EM++ F M+A D +
Sbjct: 1194 NEMEIEKKNRNSADNEKISHLEKQISDLQNKLQDKIKSQNEMVEKFKRDFQEMQAKDQKI 1253
Query: 673 ---QSHFNQIQEMLLNQ------------NVNYPLEATVNIGFDQSMDEAV----SEIAV 551
+SH +Q + LN +N+ ++ F + +++ V EI +
Sbjct: 1254 REEESHASQAKIESLNALLKQSKEENDALKMNHEIKLNKISEFTKDLEQKVKSKEQEIEL 1313
Query: 550 QTFPN----KDTEDI---NTEIAHTSDK--------DEEVIKLQSQVENLQSLVQMLKQQ 416
T N K+ D+ N+E+ SD+ +E++ +L S+++ LQ +K
Sbjct: 1314 LTQQNSVCSKEINDLHKNNSELKKLSDELQSENNVLEEKLKRLMSELKFLQE--TSVKNT 1371
Query: 415 NTKLELLAKKTSEMDPE 365
+ ++ L K SE+ E
Sbjct: 1372 DNQITNLNSKISELSEE 1388
Score = 94.4 bits (233), Expect = 2e-16
Identities = 152/745 (20%), Positives = 319/745 (42%), Gaps = 49/745 (6%)
Frame = -2
Query: 2212 EKNISEDLKETVKN--LQSDLDIE--QKLSTDRQSEIYSLSAELERITQSEQMSLKRLKE 2045
E ISE KE +N Q+D IE QK D ++E+ S AE E + + + ++ +
Sbjct: 1015 ESEISELKKELDQNNNQQNDEKIEKLQKEIEDLKNELESSKAENEELQNEFEKEIDQISQ 1074
Query: 2044 AEQTL------LEAESERESLKAELEESISVLK---------QELSSARLQIESLEKELN 1910
+Q L L+ + ++ + +L ++I L+ +++ + +IE+L++EL+
Sbjct: 1075 EKQNLESQIKYLQEKGDKSEIIDKLNQTIEELRAKVEHMFTQEDIDEYKSEIENLKQELS 1134
Query: 1909 QANEEVKVLSKFRYQ-----VLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQ 1745
E+ K +S+ + Q V ELE + +LSK+ D+ R++ K IT L+
Sbjct: 1135 NI-EKSKQISEEKSQDYEEIVHELENKLEAKETELSKLKSDFEQQTREIETLKENITNLE 1193
Query: 1744 EV--IEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDF 1571
IE+K E + ++ +D+ N L+ K+ + + + + D ++
Sbjct: 1194 NEMEIEKKNRNSADNEKISHLEKQISDLQ-NKLQDKIKSQNEMVEKFKRDFQEMQAK--- 1249
Query: 1570 SAGVFKEES----TKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEY 1403
+ +EES K+ + LL++ + +++ ++ + + ++ VK E
Sbjct: 1250 DQKIREEESHASQAKIESLNALLKQSKEENDALKMNHEIKLNKISEFTKDLEQKVKSKEQ 1309
Query: 1402 LKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLEN 1223
L N++ ++ H+ + E K S +N N+
Sbjct: 1310 EIELLTQQNSVCSKEINDLHKNNSELKKLSDELQSEN-------------------NVLE 1350
Query: 1222 EECKSKQMEEYKMLQA----ELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLN 1055
E+ K + M E K LQ +N ++ +N+++ S + E +ILK KE L
Sbjct: 1351 EKLK-RLMSELKFLQETSVKNTDNQITNLNSKI--------SELSEEINILKEKEIKLTK 1401
Query: 1054 HGQLRAEMSSLKIELVEKNG-FMGYAVLDVE-----NVQKELLIWKDRAMIAEGQSKAFQ 893
+ +++S K ++++ N + + D+E N+ + L+ R I+E +SK ++
Sbjct: 1402 EIE---KVTSEKNKIIQDNEEVVNQLMSDLEDLRRKNINLDELVENLRKEISEEKSK-YE 1457
Query: 892 LELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLK 713
+ N +I L+ + +I+++ + L +S L+ L E+++ L
Sbjct: 1458 RDTTKLNETILQLNNTVFEIKKQNEQLNLTISD-------LSTSNNLNSEKVTQEILELN 1510
Query: 712 DFIDNMEASDTNLQSHFNQIQEMLLNQNV-NYPLEATVNIGFDQSMDEAVSEIAVQTFPN 536
+ I + + NL H ++ + L + N N L T+ ++++ + +++
Sbjct: 1511 EKISKAKEENDNLSRHIEELNQQLESANEENSKLSKTIEEEKTKNLNSSEKSFSLE---- 1566
Query: 535 KDTEDINTEIAHTSDK-DEEVIKLQSQVE-------NLQSLVQMLKQQNTKLELLAKKTS 380
K+ E + E +K +EE KL+S+V NL+ +++ K+QN KL+ + +
Sbjct: 1567 KEVEKLQEEKEIFVEKSEEEKNKLKSEVTTLTEISANLKQEIEISKEQNEKLKSMLSEVE 1626
Query: 379 EMDPEKYFHFEELCQSLVXXXXXXXXXXXXXXXKNQVLVKQVKEMQVTLQSESPMEGETD 200
+ E EEL + +N + KQ++ + T++ + + +
Sbjct: 1627 SNNEELKHTIEELSSQI-----------NDLQTQNDKVEKQIENLNKTIEEK---DETIN 1672
Query: 199 SISENAIGSQPAGKLSTELHNVHGN 125
+ N+ S+ EL N N
Sbjct: 1673 KMIANSDDSEKRDNEMKELFNKQNN 1697
Score = 80.5 bits (197), Expect = 3e-12
Identities = 144/727 (19%), Positives = 296/727 (40%), Gaps = 106/727 (14%)
Frame = -2
Query: 2191 LKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTLLEAESE 2012
L E NL +D +I+ S +S + RI + E K+ ++ +Q + E +
Sbjct: 541 LDENFDNLLNDTEIQVNDSA-------LVSIQKARIDELE----KKFEQTQQIIDENK-- 587
Query: 2011 RESLKAELEESISVLKQELSSARLQIESLEKELNQANEE-----VKVLSKFRY------- 1868
EL++++++L++E + + I+S E LN+ N+E K+ SK +
Sbjct: 588 ------ELKDTLNLLQEEFHAYEMTIQSYETTLNEKNQENDKLRQKLESKGIFNQETDKK 641
Query: 1867 -----------------------QVLELEEYSQQLS-------------ADLSKVHEDYS 1796
++ +LE +QL A L K +E+Y
Sbjct: 642 DENEIKLKQLNEDYENYKKVTNEKIQQLENTKRQLQEQINNQPKPEGNLAMLQKENEEYQ 701
Query: 1795 AALRQLFDKKNEITCL----------------------------QEVIEQ---------K 1727
+ +L D K E L EV+E+ K
Sbjct: 702 RQINELKDLKTEYLKLIEEKRETDEKYNKEIEELKDRINRGEGGDEVVEELAKENDELSK 761
Query: 1726 EVEERQRECM-LAASERSNDI--NVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVF 1556
E EE + + + +SE ++ + LEK+L+ + ++ + EN+++Q ++
Sbjct: 762 ENEELKEKLKDIKSSEEIEELTNQIEELEKELNEKKEQLEQTENELTQQIEEIE------ 815
Query: 1555 KEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSN 1376
+E+S ++ + ++ ++N + E+ E K +E E+ + K ++ L+ E S
Sbjct: 816 EEKSEELKKKNEEIERLQNEIEELNKEIKSLTEEIDDLQEKLENAKKEIQELQEYAEKSQ 875
Query: 1375 TMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQME 1196
D T+ + + + ++++ D+D K E + K + +
Sbjct: 876 ENDKQTIDELKE---KLRLANETKVTDSDTKVLVESKEAAEQKVLLLEKEISDLKIEIED 932
Query: 1195 EYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKI 1016
++ E +S AE N + LE +I + K++L N+ Q E KI
Sbjct: 933 LKSVIDEENEQKVSNTEAE--------NRIHELESEISELKKELDQNNNQQNDE----KI 980
Query: 1015 ELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSEKIQQ 836
E ++K +V+D EN QK + + I E +S+ +L+ + + EKI++
Sbjct: 981 EKLQKEIEDLKSVIDEENEQK-VSNTEAENRIHELESEISELKKELDQNNNQQNDEKIEK 1039
Query: 835 IEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLK-------------DFIDNM 695
+++ + L +L + + + L + ++IS K+ L+ + ID +
Sbjct: 1040 LQKEIEDLKNELESSKAENEELQNEFEKEIDQISQEKQNLESQIKYLQEKGDKSEIIDKL 1099
Query: 694 EASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDIN 515
+ L++ +++ M ++++ N+ + S E +I+ + ++D E+I
Sbjct: 1100 NQTIEELRA---KVEHMFTQEDIDEYKSEIENLKQELSNIEKSKQISEE--KSQDYEEIV 1154
Query: 514 TEIAHTSD-KDEEVIKLQSQVENLQSLVQMLKQQNTKL----ELLAKKTSEMDPEKYFHF 350
E+ + + K+ E+ KL+S E ++ LK+ T L E+ K + D EK H
Sbjct: 1155 HELENKLEAKETELSKLKSDFEQQTREIETLKENITNLENEMEIEKKNRNSADNEKISHL 1214
Query: 349 EELCQSL 329
E+ L
Sbjct: 1215 EKQISDL 1221
Score = 76.6 bits (187), Expect = 4e-11
Identities = 133/654 (20%), Positives = 268/654 (40%), Gaps = 40/654 (6%)
Frame = -2
Query: 2242 LDAVRLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSE--------IYSLSAELER 2087
L ++ D +++ E LKE + NL+++++IE+K +E I L +L+
Sbjct: 1168 LSKLKSDFEQQTREIETLKENITNLENEMEIEKKNRNSADNEKISHLEKQISDLQNKLQD 1227
Query: 2086 ITQSEQMSLKRLKEAEQTLLE-----AESERESLKAELEESISVLKQELSSARLQIESLE 1922
+S+ +++ K Q + E E + +A++E ++LKQ + E
Sbjct: 1228 KIKSQNEMVEKFKRDFQEMQAKDQKIREEESHASQAKIESLNALLKQSKEENDALKMNHE 1287
Query: 1921 KELNQANEEVKVL-SKFRYQVLELEEYSQQ---LSADLSKVHEDYSAALRQLFDKKNEIT 1754
+LN+ +E K L K + + E+E +QQ S +++ +H++ S + + ++E
Sbjct: 1288 IKLNKISEFTKDLEQKVKSKEQEIELLTQQNSVCSKEINDLHKNNSELKKLSDELQSENN 1347
Query: 1753 CLQEVIEQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVD 1574
L+E +++ E + + S ++ D + L K+S +I L+ +LT ++
Sbjct: 1348 VLEEKLKRLMSE---LKFLQETSVKNTDNQITNLNSKISELSEEINILKEKEIKLTKEIE 1404
Query: 1573 FSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKS 1394
V E++ + + +++ ++ + L ++R + + E N+ K + KS
Sbjct: 1405 ---KVTSEKNKIIQDNEEVVNQLMSDLEDLR-RKNINLDELVENLR------KEISEEKS 1454
Query: 1393 QLETSNTMDHDTLSSTHQGSMEDKASSQS--------STGDNDPKAXXXXXXXXXXXECR 1238
+ E T ++T+ + E K ++ ST +N +
Sbjct: 1455 KYERDTTKLNETILQLNNTVFEIKKQNEQLNLTISDLSTSNN----------LNSEKVTQ 1504
Query: 1237 QNLENEECKSKQMEEYKMLQ---AELNNWLSCMNAEMGKF-----------LCLCNSMVY 1100
+ LE E SK EE L ELN L N E K L
Sbjct: 1505 EILELNEKISKAKEENDNLSRHIEELNQQLESANEENSKLSKTIEEEKTKNLNSSEKSFS 1564
Query: 1099 LEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMI 920
LE ++ K +E+ + + E + LK E+ N+++E+ I K++
Sbjct: 1565 LEKEVEKLQEEKEIFVEKSEEEKNKLKSEVTTLTEISA-------NLKQEIEISKEQ--- 1614
Query: 919 AEGQSKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEE 740
N + S+ +++ E K + +LS++ D+Q ++ E
Sbjct: 1615 ---------------NEKLKSMLSEVESNNEELKHTIEELSSQINDLQTQNDKVEKQIEN 1659
Query: 739 ISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSE 560
++ T E + I+ M A+ + + N+++E+ QN + + D+ +SE
Sbjct: 1660 LNKTIEEKDETINKMIANSDDSEKRDNEMKELFNKQNNKINELSKLIESKTSENDKLLSE 1719
Query: 559 IAVQTFPNKDTEDINTEIAHTSD-KDEEVIKLQSQVENLQSLVQMLKQQNTKLE 401
I KD N E+A D K++E LQ +++ S LK + +E
Sbjct: 1720 I-------KDLNKENEELAVLVDEKEDENHTLQVRIDEKDSENSQLKTDLSDIE 1766
Score = 67.0 bits (162), Expect = 3e-08
Identities = 134/663 (20%), Positives = 263/663 (39%), Gaps = 42/663 (6%)
Frame = -2
Query: 2227 LDIQKEKNISEDLKETVKNLQSDLDIE----QKLSTDRQSEIYSLSAELERIT-QSEQMS 2063
L+ + KNI+ D E V+NL+ ++ E ++ +T I L+ + I Q+EQ++
Sbjct: 1428 LEDLRRKNINLD--ELVENLRKEISEEKSKYERDTTKLNETILQLNNTVFEIKKQNEQLN 1485
Query: 2062 LKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVL 1883
L + L +E + + EL E IS K+E + IE L ++L ANEE L
Sbjct: 1486 LTISDLSTSNNLNSEKVTQEI-LELNEKISKAKEENDNLSRHIEELNQQLESANEENSKL 1544
Query: 1882 SKF----RYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKN----EITCLQEV---- 1739
SK + + L E S L ++ K+ E+ + + ++KN E+T L E+
Sbjct: 1545 SKTIEEEKTKNLNSSEKSFSLEKEVEKLQEEKEIFVEKSEEEKNKLKSEVTTLTEISANL 1604
Query: 1738 ---IEQKEVEERQRECMLAASERSND----------INVNALEKKLSAYEGKIRRLENDV 1598
IE + + + + ML+ E +N+ +N L+ + E +I L +
Sbjct: 1605 KQEIEISKEQNEKLKSMLSEVESNNEELKHTIEELSSQINDLQTQNDKVEKQIENLNKTI 1664
Query: 1597 SQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVV 1418
+ +++ + + + +L + N + E+ + E + E +
Sbjct: 1665 EEKDETINKMIANSDDSEKRDNEMKELFNKQNNKINELSKLIESKTSENDKLLSEIKDLN 1724
Query: 1417 KHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECR 1238
K E L ++ +H + +D +SQ T +D +
Sbjct: 1725 KENEELAVLVDEKEDENHTLQVRIDE---KDSENSQLKTDLSDIENKLNSGKELLNHTID 1781
Query: 1237 QNLENEECK----SKQMEEYKMLQAELNN------WLSCMNAEMGKFLCLCNSMVYLEGD 1088
+ ++ E K SK M L +L N ++ N E L N +V +
Sbjct: 1782 ELTKSIESKSNENSKLMSAIDQLNKDLENKNKITEEIANKNEENESKLLDLNKVV---EE 1838
Query: 1087 ILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQ 908
+ K E +L+++ + E S + +L E+ ++++ + + L ++ I
Sbjct: 1839 LKKQLEHVLIDNESEKQEKSDTEQKLREE--------IEIKEKEIDKLKKQNDQQIDHFT 1890
Query: 907 SKAFQLELKHANMSICSLSEKIQQIEEREKVLLTQLS-TKDTDMQHLAAQLTLAQEEISS 731
++ Q+ H N +I QI E + + Q+ + +M L Q EI S
Sbjct: 1891 TQISQINDDHNN--------EIDQINEDYQTQIDQIKHDHEREMNKLKEN---HQHEIES 1939
Query: 730 TKEMLKDFIDNMEASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAV 551
K+ ++D + +FN + + + +N +E +N+ F + E +
Sbjct: 1940 YKQNIEDLEHQFKEIGCKNDEYFNNLIDQINTKN-KEEIE-KLNVQFTSQISE------I 1991
Query: 550 QTFPNKDTEDINTEIAHTSDKDEEVIKLQSQ-VENLQSLVQMLKQQNTKLELLAKKTSEM 374
+ E IN + EE++K+ Q + L ++ ++ N K+ L + SE
Sbjct: 1992 NENHKNEIEQINIK------NQEEIMKINYQFTSQISELNELKEEDNKKIYELCQDNSEK 2045
Query: 373 DPE 365
E
Sbjct: 2046 KKE 2048
>gb|EAR89974.2| hypothetical protein TTHERM_00561660 [Tetrahymena thermophila SB210]
Length = 1648
Score = 100 bits (249), Expect = 3e-18
Identities = 130/654 (19%), Positives = 286/654 (43%), Gaps = 15/654 (2%)
Frame = -2
Query: 2245 TLDAVRLDIQKEKNISEDLKETVKNLQSDL-DIEQKLSTDRQSEIYSLSAELERITQSEQ 2069
T + V+ +KEK + E K+ +K LQ + DI +LST SE L EL+++ + +Q
Sbjct: 21 TYEKVKETQEKEKQLEEK-KQEIKKLQKEQDDILIQLST-IDSEKQELEKELQQLKEQQQ 78
Query: 2068 MSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLE--KELNQANEE 1895
S E+E E +++ +ELE I+ LK + +IE ++ K Q +
Sbjct: 79 QSQGNSSESEALQQELNKQKDK-HSELELEINNLKDTNQKLQAKIEEIQSHKYEEQIQQN 137
Query: 1894 VKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQE----VIEQK 1727
K +++ Q+ + +E ++ L+ L ++ + + +Q+ K+ ++ +E ++E+
Sbjct: 138 EKKIAELNSQIDKQDEENKSLNGKLQELESEIKSTHQQIAQKEQDLQKQKEDSDSLLEKT 197
Query: 1726 EVE-ERQRECMLAASERSNDIN--VNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVF 1556
++E E ++ + ++ ND N VN LE KL K N+ QL
Sbjct: 198 KLELEENKKQLDIKNQEINDANQKVNDLENKL-----KDSGSTNEEFQLKQ--------- 243
Query: 1555 KEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVK----HLEYLKSQL 1388
K+ K+S A + Q ++N L E+ + ++E + +E +K +E LK L
Sbjct: 244 KDLEDKISQADETKQGLQNKLSELEKKLDQALKEKENAQKELQDQLKMKEDEVEQLKKDL 303
Query: 1387 ETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKS 1208
+ + + Q ++ + Q G + K ++ +E E K
Sbjct: 304 DQQKQQQIQEVQNLKQDQSKEVLTLQEKIGVLESKVSEETASK------QKLIEEVEQKG 357
Query: 1207 KQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMS 1028
KQ+ + LQ ++N +++ K + N + +L+ ++
Sbjct: 358 KQVSQ---LQDQINLIKEQSSSDQDKLMEQKNQEI-----------------KELKDQIE 397
Query: 1027 SLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSICSLSE 848
+++ ++ E+ ++ ++EL +++ ++E + + + ++ N+ I S
Sbjct: 398 NIQQKIEEQTNSSNSLSEELSQAKEELKKAQEQFQLSEKEKQTLKEQISQLNLQIEEKST 457
Query: 847 KIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQS 668
+IQ+++ L +++ KD ++HL ++ T +S ++E+ K+
Sbjct: 458 QIQEVQNELSQKLNEIAQKDEKIKHLESENT---SSLSQSEELGKE-------------- 500
Query: 667 HFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDK 488
FN+I+E ++ + DQ +D + +Q + E + + +
Sbjct: 501 -FNEIREQMIQK--------------DQQIDNL--NVNIQAKEKEYNEQLQLK---EKEY 540
Query: 487 DEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEKYFH-FEELCQSL 329
E++ K+ +++NL ++ L ++N K+ + + S +KY + EEL Q++
Sbjct: 541 SEKLDKINEEIKNLNEVISQLNEEN-KIAKIQIEESNKSIQKYENDIEELKQNI 593
Score = 92.8 bits (229), Expect = 6e-16
Identities = 141/666 (21%), Positives = 288/666 (43%), Gaps = 35/666 (5%)
Frame = -2
Query: 2233 VRLDIQKEKNISEDLKETVKNLQSDLDIEQ-----KLSTDRQSEIYSLSAELERITQSEQ 2069
+ L+I K+ ++ L+ ++ +QS EQ K + S+I E + + Q
Sbjct: 104 LELEINNLKDTNQKLQAKIEEIQSHKYEEQIQQNEKKIAELNSQIDKQDEENKSLNGKLQ 163
Query: 2068 MSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVK 1889
+K Q + + E + + K + + + K EL + Q++ +E+N AN++V
Sbjct: 164 ELESEIKSTHQQIAQKEQDLQKQKEDSDSLLEKTKLELEENKKQLDIKNQEINDANQKVN 223
Query: 1888 VL-----------SKFRYQVLELE-------EYSQQLSADLSKVHEDYSAALRQLFDKKN 1763
L +F+ + +LE E Q L LS++ + AL+ +K+N
Sbjct: 224 DLENKLKDSGSTNEEFQLKQKDLEDKISQADETKQGLQNKLSELEKKLDQALK---EKEN 280
Query: 1762 EITCLQEVIEQKEVEERQRECMLAASERSNDINVNALE----KKLSAYEGKIRRLENDVS 1595
LQ+ ++ KE E Q + L ++ V L+ K++ + KI LE+ VS
Sbjct: 281 AQKELQDQLKMKEDEVEQLKKDLDQQKQQQIQEVQNLKQDQSKEVLTLQEKIGVLESKVS 340
Query: 1594 QLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSVVK 1415
+ T S +++ +VS LQ+ N ++E + + E ++ +E +
Sbjct: 341 EETASKQKLIEEVEQKGKQVSQ----LQDQINLIKEQSSSDQDKLMEQKN--QEIKELKD 394
Query: 1414 HLEYLKSQLETSNTMDHDTLSSTHQGSME-DKASSQSSTGDNDPKAXXXXXXXXXXXECR 1238
+E ++ ++E + Q E KA Q + + + +
Sbjct: 395 QIENIQQKIEEQTNSSNSLSEELSQAKEELKKAQEQFQLSEKEKQT-------LKEQISQ 447
Query: 1237 QNLENEECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLL 1058
NL+ EE KS Q++E +Q EL+ L+ + + K + +LE + L
Sbjct: 448 LNLQIEE-KSTQIQE---VQNELSQKLNEIAQKDEK-------IKHLESE----NTSSLS 492
Query: 1057 NHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKH 878
+L E + ++ ++++K+ + ++++ +KE + ++ + E K + +L
Sbjct: 493 QSEELGKEFNEIREQMIQKDQQIDNLNVNIQAKEKE---YNEQLQLKE---KEYSEKLDK 546
Query: 877 ANMSICSLSEKIQQIEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDN 698
N I +L+E I Q+ E K+ Q+ + +Q + ++ I + K+ ++ I
Sbjct: 547 INEEIKNLNEVISQLNEENKIAKIQIEESNKSIQKYENDIEELKQNIETEKKQSENQITE 606
Query: 697 M------EASDTNLQSHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPN 536
+ + D N Q + +IQE L N+NVN E +N DQ + + EI
Sbjct: 607 LQEIHKKQIEDINSQ-NIAKIQE-LENKNVNQVQE--INNSQDQ-LHKLQEEI------- 654
Query: 535 KDTEDINTEIAHTSDKDEEV-IKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEKY 359
+ +N +IA +D+++ + I+L+ +++Q +Q +K+ + LE + E ++
Sbjct: 655 ---KSLNEQIAKLNDENKIINIQLEESTKSIQKQIQDIKELSENLETQKQSAQEEIQKQK 711
Query: 358 FHFEEL 341
EEL
Sbjct: 712 SELEEL 717
Score = 91.7 bits (226), Expect = 1e-15
Identities = 160/762 (20%), Positives = 320/762 (41%), Gaps = 93/762 (12%)
Frame = -2
Query: 2230 RLDIQKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSE------- 2072
++++ ++N + +NLQ D+ QK +Q I L A+LE Q E
Sbjct: 836 QIELLNDQNSKQQADNEKQNLQIQ-DLTQK-EAQQQETINKLKADLENAKQIELNINEQN 893
Query: 2071 QMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQIESL----------E 1922
+ K+L+E++Q L + + E E L +S +E+ S + QIE L
Sbjct: 894 EAFKKQLEESKQNLSQLQKELEESSKNLSDSKENQNEEILSLKKQIEDLLNLKTELETSN 953
Query: 1921 KELNQANEEVKVLSKFRYQVLELEEYSQQLSA--DLSKVHEDYSAALRQLFDKKNEITCL 1748
++N N+E+ L + Q + EEY +Q+++ D SK +++ +L ++N+ L
Sbjct: 954 NKINTLNQEIDALKNEKQQ--KEEEYQKQINSLKDQSKNNDNNIQQETELLKQQNKK--L 1009
Query: 1747 QEVIEQ---------KEVEERQRECMLAASERSNDIN-VNALEKKLSAYEGKIRRLENDV 1598
+E +++ +E++ +++E +N +N L+ +L++ + K + E +
Sbjct: 1010 EEQLKELKDSELQILEEIQNKEKEVDDFKQINEQQLNEINQLKDELASQKQKDNQQEQET 1069
Query: 1597 ---SQLT-LSVDFSAGVFKEESTKVSNACDLLQEIENFLRE-IRVETKVTIQEARHNVEE 1433
SQL L V + V + +K+ L ++ EN RE + E ++ +++ N
Sbjct: 1070 QGESQLDELKVKYEQ-VELDLKSKLEEINQLQKQNENLQREKLDFEKEIADMKSQLNSTA 1128
Query: 1432 FSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXX 1253
FSS + S + S T + +L ST + E+K ++ + D K
Sbjct: 1129 FSSSNNIINLENSAMNDSTTPRNSSLVSTPVNN-EEKKDNEDKKDEKDKKE--------- 1178
Query: 1252 XXECRQNLENEECKSKQMEEYKMLQAELNNW-------------LSCMNAEMGKFLCLCN 1112
++ +++E KS + + KM EL W L N ++ + L +
Sbjct: 1179 ----EKDKKSKEAKSDKQQTVKMTLEELKKWDEQVKELKKKRKELEKENKQLKQELEEKS 1234
Query: 1111 SMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKN---------------------- 998
D LK E QL + +LKIEL EKN
Sbjct: 1235 KQPVQNIDSLKQIES---QKRQLEQQYMNLKIELEEKNKLQQSQQIKKNLNLESLEERCR 1291
Query: 997 ---GFMGYAVLDVENVQKELLIWKDRAMIAEGQSKAFQLELKHANMSI---CSLSEKIQQ 836
G + ++++ +E WK++ + A + ELK S +L +Q
Sbjct: 1292 ILQGLLDENSVNLQKADREREYWKEKYTGLQEDFNAKEEELKIQRESAREKFNLEMTLQS 1351
Query: 835 IEEREKVLLTQLSTKDTDMQ---HLAAQLTLAQEEISSTKEM---LKDFIDNMEASDTNL 674
++ L Q+ + ++Q L A ++E + +E+ L++ ++N E + L
Sbjct: 1352 QIQQNSSLNKQIQEYERNLQAYKQLNADNENLKKECAKLRELVDKLQEELENKERNQEKL 1411
Query: 673 QSHFNQIQEM--LLNQNVNYPLEATVNIGFDQS-MDEAVSEIAVQTFPNKDTEDIN---- 515
N++ E+ + +NY + + + +S +++ + I Q +++ + IN
Sbjct: 1412 SHKLNELNELNDEYQKKINYLEKQSERLQNQKSELEQNLQSITTQLEDSQNIQKINQKKY 1471
Query: 514 ----TEIAHTSD-KDEEVIKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEKYFHF 350
EI D ++V +L+++ E+L++ V+ L++ N K T ++PE
Sbjct: 1472 QNEVLEIKQVRDGLVQQVKELKTKNESLENDVRSLREANKK---QFHSTINVNPETAKKD 1528
Query: 349 EELCQSLVXXXXXXXXXXXXXXXKNQVLVKQVKEMQVTLQSE 224
+ + +SL K + + KQ+KE+ L+S+
Sbjct: 1529 KIILESLSIRNQELEVQSKQQKDKIEFMDKQIKEIHKVLESK 1570
Score = 89.4 bits (220), Expect = 6e-15
Identities = 139/704 (19%), Positives = 295/704 (41%), Gaps = 78/704 (11%)
Frame = -2
Query: 2221 IQKEKNISEDLKETVKNLQSDLDI-EQKLSTDRQSEIYSL-------------------- 2105
IQ+ +N+ +D + V LQ + + E K+S + S+ +
Sbjct: 311 IQEVQNLKQDQSKEVLTLQEKIGVLESKVSEETASKQKLIEEVEQKGKQVSQLQDQINLI 370
Query: 2104 ----SAELERITQSEQMSLKRLKEAEQTLLEAESERESLKAELEESISVLKQELSSARLQ 1937
S++ +++ + + +K LK+ + + + E+ + L E +S K+EL A+ Q
Sbjct: 371 KEQSSSDQDKLMEQKNQEIKELKDQIENIQQKIEEQTNSSNSLSEELSQAKEELKKAQEQ 430
Query: 1936 IESLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSKVHEDYSAALRQLFDKKNEI 1757
+ EKE E++ L+ L++EE S Q + +V + S L ++ K +I
Sbjct: 431 FQLSEKEKQTLKEQISQLN------LQIEEKSTQ----IQEVQNELSQKLNEIAQKDEKI 480
Query: 1756 TCLQ----EVIEQKEVEERQ----RECMLAASERSNDINVNALEKKLSAYEGKIRRLEND 1601
L+ + Q E ++ RE M+ ++ +++NVN ++ K Y +++ E +
Sbjct: 481 KHLESENTSSLSQSEELGKEFNEIREQMIQKDQQIDNLNVN-IQAKEKEYNEQLQLKEKE 539
Query: 1600 VSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETKVTIQEARHNVEEFSSV 1421
+ E+ K++ L E+ + L E K+ I+E+ +++++ +
Sbjct: 540 --------------YSEKLDKINEEIKNLNEVISQLNEENKIAKIQIEESNKSIQKYEN- 584
Query: 1420 VKHLEYLKSQLETSNTMDHD---TLSSTHQGSMED-----KASSQSSTGDNDPKAXXXXX 1265
+E LK +ET + L H+ +ED A Q N +
Sbjct: 585 --DIEELKQNIETEKKQSENQITELQEIHKKQIEDINSQNIAKIQELENKNVNQVQEINN 642
Query: 1264 XXXXXXECRQNLEN-EECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSM----VY 1100
+ ++ +++ E +K +E K++ +L + ++ L ++
Sbjct: 643 SQDQLHKLQEEIKSLNEQIAKLNDENKIINIQLEESTKSIQKQIQDIKELSENLETQKQS 702
Query: 1099 LEGDILKYKEDL-LLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVENVQKELL------- 944
+ +I K K +L L+ Q+ + + ++ E V ++ N K+L+
Sbjct: 703 AQEEIQKQKSELEELHKKQIESINNQNNTKIQELENSHSNKVEELNNSHKKLIEELEDSH 762
Query: 943 --IWKDRAMIAEGQSKAFQLELKHANMSICSLSEKI--------QQIEEREKV---LLTQ 803
+ +D + K Q L SL E+I QQ ER+K+ L Q
Sbjct: 763 KKVTEDIQHKNAHELKKIQEILSETQQREKSLQEQISLHSMGAEQQEVERQKIIKDLENQ 822
Query: 802 LSTKDTDMQHLAAQLTL-----AQEEISSTKEMLKDFIDNMEASDTNLQSHFNQIQEMLL 638
+ K M++L Q+ L ++++ + K+ L+ I ++ + Q N+++ L
Sbjct: 823 IKEKADQMRNLEDQIELLNDQNSKQQADNEKQNLQ--IQDLTQKEAQQQETINKLKADLE 880
Query: 637 NQ-----NVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSD-KDEEV 476
N N+N EA F + ++E+ ++ K+ E+ + ++ + + ++EE+
Sbjct: 881 NAKQIELNINEQNEA-----FKKQLEESKQNLSQL---QKELEESSKNLSDSKENQNEEI 932
Query: 475 IKLQSQVENLQSLVQMLKQQNTKLELLAKKTSEMDPEKYFHFEE 344
+ L+ Q+E+L +L L+ N K+ L ++ + EK EE
Sbjct: 933 LSLKKQIEDLLNLKTELETSNNKINTLNQEIDALKNEKQQKEEE 976
>gb|EMG48182.1| hypothetical protein G210_1294 [Candida maltosa Xu316]
Length = 2274
Score = 100 bits (249), Expect = 3e-18
Identities = 128/641 (19%), Positives = 269/641 (41%), Gaps = 26/641 (4%)
Frame = -2
Query: 2218 QKEKNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAE 2039
++ K+ S+ L + + L+S ++ K + S SL E+E++ + L +
Sbjct: 1499 KENKDSSDKLSKEITELKSQIESINKTLAESNSTKESLQDEVEKLNKQITAKSDELDDKN 1558
Query: 2038 QTLLEAESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQVL 1859
+ L E E+E + + ELE + + +LS + ++++++ EL ++ +K S+ + + L
Sbjct: 1559 KQLAEKETELTNTRKELETT----QADLSKTQEELKNIKDELEKSKAAIKD-SQVKLKDL 1613
Query: 1858 ELEEYSQQLSADLSKVHEDYSAALRQLFDK-KNEITCLQEVIEQKEVE----ERQRECML 1694
E E+ A+L + L++L +K K E T L E +++KE + + + + +
Sbjct: 1614 ESEK------AELETTIKMVKTELKELQNKYKKETTSLNEKVDEKEKQIVSLKNELKDRI 1667
Query: 1693 AASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLL 1514
+ E+ + + E + Y KI+ LE +S+L S +E T + D +
Sbjct: 1668 SEVEKERAMLSESSETVIQEYSDKIKVLEGKISELKESHTKEISKHVDEKTSLKTDIDKI 1727
Query: 1513 QEIENFLREIRVETKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGS 1334
+ L+ + K L LKSQL+ + L++ + S
Sbjct: 1728 TSDHDTLK-----------------DSLEGKTKELTDLKSQLDKATKKSESDLNA--KQS 1768
Query: 1333 MEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLENEECKSKQMEEYKMLQAELNNWLS 1154
DK SS+ T ++ + EN E K +E K L+ L
Sbjct: 1769 EVDKLSSEIKTLNDAISKKDQELTAIQSDYDKLKSENSEINKKLDKESKSLKDAL----- 1823
Query: 1153 CMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVEKNGFMGYAVL 974
A + K+ + + L+ + E L N E+ LK +L E
Sbjct: 1824 ---ASVEKYKNDLSEITKLKTQLSSDLESLKANSTSTGTELLELKKKLEESRKETETLSA 1880
Query: 973 DVENVQKEL---------LIWKDRAMIAEGQSKAFQL-----ELKHANMSICSLSEKIQQ 836
+++ KEL L K ++ E + +A +L E++ + + ++++++
Sbjct: 1881 SLDDKSKELDSHLEKHEELTEKHATLLKEHKDRAIELDSSKKEIQDSVSKLSTITKELND 1940
Query: 835 IEEREKVLLTQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQSHFNQ 656
+E+ ++ + +K+++++ L A++T ++ S + + K + +E+ L+
Sbjct: 1941 AKEKHAETVSLVESKNSEIEQLQAEITKMKDNESQSGKEAKSMVSKLESEIETLKKDLAD 2000
Query: 655 IQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEV 476
+ + LE +V + + + T +D++ + + D DE +
Sbjct: 2001 KESEIKRLG---ELENSVKSKNTEIEQLETEKTKLSTDLESVKKDLDAALKYKKDLDEAL 2057
Query: 475 IKLQ---SQVENLQSLVQML----KQQNTKLELLAKKTSEM 374
KL+ +Q+ S+V+ L K+ + KLE L KK SE+
Sbjct: 2058 SKLEDSNTQLSKSNSVVEKLETDKKKSDEKLEELTKKHSEL 2098
Score = 87.0 bits (214), Expect = 3e-14
Identities = 140/722 (19%), Positives = 300/722 (41%), Gaps = 99/722 (13%)
Frame = -2
Query: 2209 KNISEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTL 2030
K+++ DL++ K + Q + + + +I L+ +L + Q ++ ++K+L+E Q
Sbjct: 1021 KSLNNDLEKNKKTFDGQIKSLQTSNAEFKQKIADLNTQLTSVVQDKETTVKQLQEKLQDT 1080
Query: 2029 LE-AESERESLKA------ELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFR 1871
E +E + L++ EL++S S ++E++ Q++ E ++ + +E + + +
Sbjct: 1081 EENSEHLMDKLRSASVAFNELKKSNSDAEEEITKVNSQVKEFESKIAELSESLDKSNAEK 1140
Query: 1870 YQVLE---------------LEEYSQQLSADLSKVHEDYSAALRQLFDKKNEITCLQEVI 1736
+V E LEE Q +++ + + + S +L KN+ T Q+
Sbjct: 1141 QEVQEKLNALESSTSEKIQALEEELQNVTSSGTDLTDKNSKLTEELTKLKNDFTAKQDEF 1200
Query: 1735 EQKEVEERQRECMLAASERSNDINVNALEKKLSAYEGKIRRLENDVSQLTLSVDFSAGVF 1556
+ + E +L A + N+ EK +S + L + L + +
Sbjct: 1201 DALKEESGSTIKILTAEIETLKANLEESEKLISNTKNDHSTLSENFQNLKEEYESAKTTL 1260
Query: 1555 KEE-STKVSN----ACDLLQEIENF--LREIRVETKVTIQEARHNVE-EFSSVVKHLEYL 1400
E+ S K+ A +L Q+I++ L+E + K + + V+ SV K L+
Sbjct: 1261 NEKLSAKIDEYEKVAAELEQKIKDMLSLQEEHAKEKEVLNDKHDKVKLNLESVTKELDQH 1320
Query: 1399 KSQLETSNTMDHDTL--SSTHQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLE 1226
KS+L + N + + S H+ ++ED + S ++ KA + LE
Sbjct: 1321 KSELASINEKHAEVVGKSQKHESTIED---LEMSIEISEEKAKSLKKDVEELKAAKSTLE 1377
Query: 1225 NE--------ECKSKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKE 1070
E KSK++ E ++ E+ + L+ + + G++ K KE
Sbjct: 1378 ETLKLKESSIEEKSKEVAEAQLKIKEIESSLAKLEEQK-------------NGELSKLKE 1424
Query: 1069 DLLLNHGQLRAEMSSLKIELVEKNGFMGYAVLDVE------NVQKELLIWKDRAMIAEGQ 908
+L + E+S+L +L N D+ +K I + + + +
Sbjct: 1425 ELESLQTEKDEEISNLSEKLETANKKSSDVEQDLSEKLSKLESEKNAEIEQHKGSLTKKA 1484
Query: 907 SKAFQLELKHANM------SICSLSEKI----QQIEEREKVLL----------------- 809
+ +ELK AN S LS++I QIE K L
Sbjct: 1485 EELKAVELKFANATKENKDSSDKLSKEITELKSQIESINKTLAESNSTKESLQDEVEKLN 1544
Query: 808 --------------TQLSTKDTDMQHLAAQLTLAQEEISSTKEMLKDFIDNMEASDTNLQ 671
QL+ K+T++ + +L Q ++S T+E LK+ D +E S ++
Sbjct: 1545 KQITAKSDELDDKNKQLAEKETELTNTRKELETTQADLSKTQEELKNIKDELEKSKAAIK 1604
Query: 670 SHFNQIQEMLLNQNVNYPLEATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSD 491
+++++ ++ LE T+ + + + +Q K+T +N ++ +
Sbjct: 1605 DSQVKLKDL---ESEKAELETTIKMVKTELKE-------LQNKYKKETTSLNEKV---DE 1651
Query: 490 KDEEVIKLQSQVENLQSLVQ------------MLKQQNTKLELLAKKTSEMDPEKYFHFE 347
K+++++ L++++++ S V+ ++++ + K+++L K SE+ K H +
Sbjct: 1652 KEKQIVSLKNELKDRISEVEKERAMLSESSETVIQEYSDKIKVLEGKISEL---KESHTK 1708
Query: 346 EL 341
E+
Sbjct: 1709 EI 1710
Score = 79.3 bits (194), Expect = 6e-12
Identities = 129/600 (21%), Positives = 254/600 (42%), Gaps = 45/600 (7%)
Frame = -2
Query: 1993 ELEESISVLKQELSSARLQIESLEKELNQANEEVKVLSKFRYQVLELEEYSQQLSADLSK 1814
EL+ + + ++L + + + EK LN+ E+ LSK LE + +L+K
Sbjct: 864 ELDSKVFDITKQLKEEKDKAQDTEKSLNEKISELTDLSK------NLESKLDENEKELTK 917
Query: 1813 VHEDYSAALRQLFDKKNEITCLQEVIEQKEVE----ERQRECMLAASE-RSNDINVNALE 1649
V D+S+ QL + N ++ +++ +KE E + Q+E A + S+D L+
Sbjct: 918 VKNDHSSVTEQLTNTANNLSVMEK--SKKEFESSSAKYQKELQDALKKGSSSDELTKDLK 975
Query: 1648 KKLSAYEGKIRRLENDVSQLTLSVDFSAGVFKEESTKVSNACDLLQEIENFLREIRVETK 1469
KL + E ++LE+ ++ +T + E +K+ L+ + N L + +
Sbjct: 976 SKLDSTEKAKKKLEDGINNMTRDLFHLKKQKGEAESKIKQLEGDLKSLNNDLEKNKKTFD 1035
Query: 1468 VTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSSTHQGSMEDKASSQSSTGDND 1289
I+ + + EF + L +QL TS D +T Q ++D + D
Sbjct: 1036 GQIKSLQTSNAEFKQKIAD---LNTQL-TSVVQDKETTVKQLQEKLQDTEENSEHLMD-- 1089
Query: 1288 PKAXXXXXXXXXXXECRQNLENEECK-SKQMEEYKMLQAELNNWLSCMNAEMGKFLCLCN 1112
K + + E E K + Q++E++ AEL+ L NAE + N
Sbjct: 1090 -KLRSASVAFNELKKSNSDAEEEITKVNSQVKEFESKIAELSESLDKSNAEKQEVQEKLN 1148
Query: 1111 SMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELVE-----KNGFMGYAVLDVENVQKEL 947
++ + ++ E+ L N +++ +L E KN F A D + KE
Sbjct: 1149 ALESSTSEKIQALEEELQNVTSSGTDLTDKNSKLTEELTKLKNDFT--AKQDEFDALKEE 1206
Query: 946 LIWKDRAMIAEGQSKAFQLE-----LKHANMSICSLSEKIQQIEER----EKVLLTQLST 794
+ + AE ++ LE + + +LSE Q ++E + L +LS
Sbjct: 1207 SGSTIKILTAEIETLKANLEESEKLISNTKNDHSTLSENFQNLKEEYESAKTTLNEKLSA 1266
Query: 793 KDTDMQHLAAQL-------TLAQEEISSTKEMLKDFID----NMEASDTNLQSHFNQIQE 647
K + + +AA+L QEE + KE+L D D N+E+ L H +++
Sbjct: 1267 KIDEYEKVAAELEQKIKDMLSLQEEHAKEKEVLNDKHDKVKLNLESVTKELDQHKSELAS 1326
Query: 646 M-----------LLNQNVNYPLEATVNIGFD--QSMDEAVSEIAVQTFPNKDTEDINTEI 506
+ +++ LE ++ I + +S+ + V E+ ++T + +
Sbjct: 1327 INEKHAEVVGKSQKHESTIEDLEMSIEISEEKAKSLKKDVEELKAAKSTLEET--LKLKE 1384
Query: 505 AHTSDKDEEVIKLQSQVENLQ-SLVQMLKQQNTKLELLAKKTSEMDPEKYFHFEELCQSL 329
+ +K +EV + Q +++ ++ SL ++ +Q+N +L L ++ + EK L + L
Sbjct: 1385 SSIEEKSKEVAEAQLKIKEIESSLAKLEEQKNGELSKLKEELESLQTEKDEEISNLSEKL 1444
Score = 74.3 bits (181), Expect = 2e-10
Identities = 125/686 (18%), Positives = 273/686 (39%), Gaps = 76/686 (11%)
Frame = -2
Query: 2200 SEDLKETVKNLQSDLDIEQKLSTDRQSEIYSLSAELERITQSEQMSLKRLKEAEQTLLEA 2021
S+ + T+++L+ ++I ++ + + ++ L A + ++ ++ ++E + + EA
Sbjct: 1338 SQKHESTIEDLEMSIEISEEKAKSLKKDVEELKAAKSTLEETLKLKESSIEEKSKEVAEA 1397
Query: 2020 ESERESLKAELEESISVLKQELSSARLQIESLEKELNQANEEVKVLS-KFRYQVLELEEY 1844
+ + + +++ L + ELS + ++ESL+ E +EE+ LS K + +
Sbjct: 1398 QLKIKEIESSLAKLEEQKNGELSKLKEELESLQTE---KDEEISNLSEKLETANKKSSDV 1454
Query: 1843 SQQLSADLSKVHEDYSAALRQ----LFDKKNEITCLQEVIEQKEVEERQRECMLAASERS 1676
Q LS LSK+ + +A + Q L K E+ ++ E + L+
Sbjct: 1455 EQDLSEKLSKLESEKNAEIEQHKGSLTKKAEELKAVELKFANATKENKDSSDKLSKEITE 1514
Query: 1675 NDINVNALEKKLSAYEGKIRRLENDVSQLTLSV-------DFSAGVFKEESTKVSNACDL 1517
+ ++ K L+ L+++V +L + D E+ T+++N
Sbjct: 1515 LKSQIESINKTLAESNSTKESLQDEVEKLNKQITAKSDELDDKNKQLAEKETELTNTRKE 1574
Query: 1516 LQEIENFLREIRVE---TKVTIQEARHNVEEFSSVVKHLEYLKSQLETSNTMDHDTLSST 1346
L+ + L + + E K +++++ +++ +K LE K++LET+ M L
Sbjct: 1575 LETTQADLSKTQEELKNIKDELEKSKAAIKDSQVKLKDLESEKAELETTIKMVKTELKEL 1634
Query: 1345 HQGSMEDKASSQSSTGDNDPKAXXXXXXXXXXXECRQNLEN---EECKSKQMEEY----K 1187
Q + + +S + D K E E ++EY K
Sbjct: 1635 -QNKYKKETTSLNEKVDEKEKQIVSLKNELKDRISEVEKERAMLSESSETVIQEYSDKIK 1693
Query: 1186 MLQAELNNWLSCMNAEMGKFLCLCNSMVYLEGDILKYKEDLLLNHGQLRAEMSSLKIELV 1007
+L+ +++ E+ K + + L+ DI K D H L+ + EL
Sbjct: 1694 VLEGKISELKESHTKEISKHV---DEKTSLKTDIDKITSD----HDTLKDSLEGKTKELT 1746
Query: 1006 EKNGFMGYAV-----------LDVENVQKELLIWKDRAMIAEGQSKAFQLE---LKHANM 869
+ + A +V+ + E+ D + + A Q + LK N
Sbjct: 1747 DLKSQLDKATKKSESDLNAKQSEVDKLSSEIKTLNDAISKKDQELTAIQSDYDKLKSENS 1806
Query: 868 SI--------CSLSEKIQQIEEREKVL--LTQLSTK-DTDMQHLAAQLTLAQEEISSTKE 722
I SL + + +E+ + L +T+L T+ +D++ L A T E+ K+
Sbjct: 1807 EINKKLDKESKSLKDALASVEKYKNDLSEITKLKTQLSSDLESLKANSTSTGTELLELKK 1866
Query: 721 MLKD-------FIDNMEASDTNLQSHFNQIQEM------LLNQNVNYPLE---------- 611
L++ +++ L SH + +E+ LL ++ + +E
Sbjct: 1867 KLEESRKETETLSASLDDKSKELDSHLEKHEELTEKHATLLKEHKDRAIELDSSKKEIQD 1926
Query: 610 -----ATVNIGFDQSMDEAVSEIAVQTFPNKDTEDINTEIAHTSDKDEEVIK-LQSQVEN 449
+T+ + + ++ +++ N + E + EI D + + K +S V
Sbjct: 1927 SVSKLSTITKELNDAKEKHAETVSLVESKNSEIEQLQAEITKMKDNESQSGKEAKSMVSK 1986
Query: 448 LQSLVQMLKQQNTKLELLAKKTSEMD 371
L+S ++ LK+ E K+ E++
Sbjct: 1987 LESEIETLKKDLADKESEIKRLGELE 2012