BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Ephedra28_contig00013072
         (2739 letters)

Database: ./nr 
           37,332,560 sequences; 13,225,080,153 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_001765725.1| predicted protein [Physcomitrella patens] gi...   785   0.0  
gb|EFA79656.1| DNA-dependent protein kinase subunit [Polysphondy...   494   e-137
ref|XP_640856.2| DNA-dependent protein kinase  subunit [Dictyost...   475   e-131
ref|XP_003286510.1| DNA-dependent protein kinase subunit [Dictyo...   471   e-129
ref|XP_004350354.1| DNA-dependent protein kinase subunit [Dictyo...   466   e-128
ref|XP_002965996.1| hypothetical protein SELMODRAFT_84321 [Selag...   439   e-120
ref|XP_002989230.1| hypothetical protein SELMODRAFT_129513 [Sela...   439   e-120
ref|XP_004454094.1| PREDICTED: DNA-dependent protein kinase cata...   382   e-103
ref|NP_001157330.1| DNA-dependent protein kinase catalytic subun...   382   e-103
gb|AAL40980.1| DNA-dependent protein kinase catalytic subunit [E...   381   e-102
gb|EHH28470.1| DNA-dependent protein kinase catalytic subunit [M...   379   e-102
ref|XP_005563337.1| PREDICTED: DNA-dependent protein kinase cata...   379   e-102
ref|XP_005563336.1| PREDICTED: DNA-dependent protein kinase cata...   379   e-102
ref|XP_001100610.2| PREDICTED: DNA-dependent protein kinase cata...   379   e-102
ref|XP_003902769.1| PREDICTED: DNA-dependent protein kinase cata...   379   e-102
ref|XP_003777295.1| PREDICTED: LOW QUALITY PROTEIN: DNA-dependen...   378   e-102
gb|EHH64150.1| DNA-dependent protein kinase catalytic subunit [M...   377   e-101
ref|NP_008835.5| DNA-dependent protein kinase catalytic subunit ...   375   e-101
gb|EAW86683.1| protein kinase, DNA-activated, catalytic polypept...   375   e-101
ref|XP_006221286.1| PREDICTED: DNA-dependent protein kinase cata...   374   e-101

>ref|XP_001765725.1| predicted protein [Physcomitrella patens] gi|162683151|gb|EDQ69564.1|
            predicted protein [Physcomitrella patens]
          Length = 4165

 Score =  785 bits (2028), Expect = 0.0
 Identities = 416/923 (45%), Positives = 601/923 (65%), Gaps = 10/923 (1%)
 Frame = -1

Query: 2739 ELASLAVVTDQFDLAVFYLKKFYESFRMKWSSVHPLATASKHILLKKLQQVVELDEYVEH 2560
            +LA+LA +  ++D A FYL + +  FR +WS++HP A  S+H  +++LQ++VEL+E++  
Sbjct: 3111 QLATLAAINKEWDRARFYLGQCHLIFRRQWSALHPFALGSRHQRVRQLQKIVELEEFITF 3170

Query: 2559 ITKERNEASLTRLFNVWHKRWPSPQFDDVEAWDDVLQNRLLYFEKTQQLVGRQLLKE--D 2386
            I+K      L+RL + WHKRWPSP FDDVEAWDD+ QNRLL+ +  Q+     + +   D
Sbjct: 3171 ISKPE-AGELSRLLSGWHKRWPSPNFDDVEAWDDIAQNRLLFLKYIQEHFNNPVQRNSFD 3229

Query: 2385 GDFDKQRVVDLDFEKANIFYEAARGLILQGSYDASQGYMNQYMAAIEGSNKKEKLNFDFF 2206
              F       +D E+A++    A GL+  G+   +Q Y+N+YM++    + K +L+F  F
Sbjct: 3230 DKFCNSISSLIDAERAHLHVAVANGLMECGALPVAQSYINRYMSSKFEFSAKHRLDFRNF 3289

Query: 2205 NTLVKLRCLQADRESTIDAFEAVTMLQQVRDYVTSTARKALYQNQTKWRAGLKMLEGDVT 2026
              LV+L+CL+A+R+ +  A   +  LQQ+  Y+ +  RK       ++    +M + DV 
Sbjct: 3290 KALVRLQCLRAERDES--ANNRIKKLQQLLVYIETERRKL--SKHPEFLPEFQMEQADVN 3345

Query: 2025 SKLATFSLKSLSENSVSPKEIENCVSLFGSAYAAYSKLF------SEVSSADPFVHDEFF 1864
            +++A  +L S S    + ++I  C +L GSA+  YS         SE+++     HD   
Sbjct: 3346 ARVAWATLSSQSGEGATSQDITACFALLGSAFKTYSTALDNDDPLSEITTGSLSPHDT-- 3403

Query: 1863 TSRKIAKAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKGDVSASLPPSSEYPVLVVRYIM 1684
                 AKA +KF  FCDELL  ++Q      +      G     LP +S+  +LVVR+++
Sbjct: 3404 -----AKALLKFGLFCDELLKLSQQPEERSQMTQHHLFG-----LPQASDLSLLVVRHML 3453

Query: 1683 KAIQMDINLQIQHGIARVLTLLGHYSNTHSEFVHQQNGIPCWLFIAWIPQILAVLEKEEG 1504
            KA+ +D  LQ QH +AR+L+L+G  S T +EF    + +  W+F+AWIPQ+LA +E++ G
Sbjct: 3454 KALALDSTLQAQHAVARLLSLVGFSSATQNEFERFLDNVSSWVFVAWIPQMLANIEEDSG 3513

Query: 1503 AVLVSVLEDIAHLYPQALYFPYNASKSDFGPIGQERTSKISALLNNPLLNGLVHALEDLT 1324
             VL+ VLE IA  YPQALYFP+  S++DFG IG++RT  +  LL NPLL GLV ALEDLT
Sbjct: 3514 RVLIKVLESIAKSYPQALYFPFRVSETDFGAIGRQRTQHLKILLRNPLLEGLVRALEDLT 3573

Query: 1323 YPEQRLQYWLSHIRNCISVGNTKDAEATFHQMFEDCLDSEAMSS--RKSGTYNEKFAKDY 1150
            +P+QRL+  L  I N +   +++ A+  F+++++DCLD++++    R++G YN KFA+D+
Sbjct: 3574 FPQQRLKDGLLQILNFLFTNDSERAQLVFNEIYQDCLDTQSLKDPVRQTGEYNLKFARDW 3633

Query: 1149 SKKVLKALGMNGSKLQSMDEKKYAESIKDLAENLAKSQRNLQTGKISLGSLSKWMAEYDE 970
            +  ++K LG+NGSKL+SMD K+++  I  L E L+K+  ++   KISLGSLSKW+A++D+
Sbjct: 3634 ASLIVKELGLNGSKLRSMDAKQFSSVISGLFEKLSKN--DISAEKISLGSLSKWLADFDQ 3691

Query: 969  SGVFVRQVAXXXXXXXXXXXXXXXXXXXIPGHYTGFKKPDPSSHVKLISFDQTLTCLSSK 790
            +    R                      IPG Y G   P+ S+HV+L+ FDQ L CL SK
Sbjct: 3692 TKGIER---------VSRDFDKNEMQIEIPGQYNGSSIPNLSTHVQLLGFDQVLICLKSK 3742

Query: 789  QRPKILKMRGSDEKDYKFLVKGGEDLRLDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYA 610
            QRPKIL MRGSDE DYKF+VKGGEDLRLDQRIEQLF  MN +L+RD  CS++KL++RTY+
Sbjct: 3743 QRPKILTMRGSDENDYKFVVKGGEDLRLDQRIEQLFEAMNNVLNRDAACSQRKLAIRTYS 3802

Query: 609  VVPISKQCGVIEFIEDTSVIDDVIRDGLMHKMPSVRHATSKQEKNTPAGLLSSLRTQYQD 430
            V+P+SK+CG+++F+E+T V+ +VIRDGL  K+ S  H   K  + T   LL  ++ +Y +
Sbjct: 3803 VIPVSKKCGLLQFVENTCVLQEVIRDGLSSKLASRTHEGYKPLQATSETLLKEIQHEYIE 3862

Query: 429  WILKKGGSSAKLSESYTNMYKKASAEDIKKEMEILTSQLPWDALKTGISKLATSAESFLA 250
            W+ KKGG  ++ +E Y N+Y+K   E++  ++  L  QLPWD L+ G S+L TSAES+LA
Sbjct: 3863 WVRKKGGGKSQ-TECYCNLYRKVGFEEVSLKLSALQGQLPWDTLRMGFSRLVTSAESYLA 3921

Query: 249  LRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDFGYSFGTGVILLPVPELI 70
            LRSQF RSLS  SIC YVAGVGDRHL N L+D + G L+PIDFGYSFGT V+LLPVPEL+
Sbjct: 3922 LRSQFARSLSVTSICGYVAGVGDRHLGNTLVDMRTGALVPIDFGYSFGTNVLLLPVPELV 3981

Query: 69   PFRLTPQFTNVLLPLDAVGLLRN 1
            PFRLT Q  N LLPL AVGLLR+
Sbjct: 3982 PFRLTAQLKNFLLPLTAVGLLRS 4004


>gb|EFA79656.1| DNA-dependent protein kinase subunit [Polysphondylium pallidum PN500]
          Length = 4074

 Score =  494 bits (1272), Expect = e-137
 Identities = 306/935 (32%), Positives = 491/935 (52%), Gaps = 24/935 (2%)
 Frame = -1

Query: 2739 ELASLAVVTDQFDLAVFYLKKFYESFRMKWSSVHPLATASKHILLKKLQQVVELDEYVEH 2560
            ELA L +    F+ + +Y++KFY  FR +W+S HPLA AS+H +L+ +Q+VVE++E++  
Sbjct: 3058 ELAFLEITRSDFNRSQYYIQKFYRLFRDQWASTHPLALASRHRILQPIQKVVEVEEFLGL 3117

Query: 2559 ITKERNEAS---LTRLFNVWHKRWPSPQFDDVEAWDDVLQNRLLYFEKTQQLVGRQLLKE 2389
            +T ++       + +L ++W  R+PS  FDD+  WDD++  R +  EK  +   R + + 
Sbjct: 3118 VTNDKRAIEVDKMEKLVSLWKTRYPS-SFDDILVWDDLVSFRSVLLEKIYE---RFIGQN 3173

Query: 2388 DGDFDKQRVVD--LDFEKANIFYEAARGLILQGSYDASQGYMNQYMAAIEGSNKKEKLNF 2215
            + D  K+  V   L  E+A ++++ ++G    G+   S+ Y    + +   + + + L F
Sbjct: 3174 NNDEAKEDGVKNLLIRERAELYHQMSKGARKLGNIIVSEAYFRLAVKSYPKTREND-LAF 3232

Query: 2214 DFFNTLVKLRCLQADRESTIDAFEAVTMLQQVRDYVTSTARKALYQNQTKWRAGLKMLEG 2035
               ++L+K+ CL+A   +T    E +    +   +V S + +   +N        K L G
Sbjct: 3233 PLVSSLIKIYCLKAKNSTT--QVETLDRFIKALKFVESKSDEDSIKNNPDNLQRYKRLHG 3290

Query: 2034 DVT-----------SKLATFSLKSLSENSVSPKEIENCVS-LFGSAYAAYSKLFSEVSSA 1891
            ++            S L   +LK     S+S        S LF  AY +YS+      S 
Sbjct: 3291 NIQWEIYQLDQKLGSNLVMENLKKNGLTSLSSLPTTRLSSELFSLAYQSYSQSIQLYDSN 3350

Query: 1890 DPFVHDEFFTSRKIAKAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKGDVSASLPPSSEY 1711
                +D    + K   AY++F  FCD  L                ++GD S     S+  
Sbjct: 3351 SNNNND----THKSKSAYLQFGNFCDTELQ---------------RRGDQSED---SNRL 3388

Query: 1710 PVLVVRYIMKAIQMDINLQIQHGIARVLTLLGHYSNTHSEFVHQQNGIPCWLFIAWIPQI 1531
             V VV  IM AI+ +I   I+    R+L ++  Y     EFV +   IPCW+FI W  Q+
Sbjct: 3389 AVSVVNSIMNAIKQEIPGAIEK-FPRLLEIISQYEKAAKEFVERTKQIPCWMFIRWQSQM 3447

Query: 1530 LAVLEKEEGAVLVSVLEDIAHLYPQALYFPYNASKSDFGPIGQERTSKISALLNNPLLNG 1351
               L+  +G  ++ +L++IA  YPQA+YFP+  S   FGP  ++ T+K+   L NPL++ 
Sbjct: 3448 FPYLDTPQGPYILPILQEIASNYPQAIYFPFKISSEQFGPTAKKLTAKLEQTLKNPLIDT 3507

Query: 1350 LVHALEDLTYPEQRLQYWLSHIRNCISVG--NTKDAEATFHQMFEDCLDSEAMSSRKSGT 1177
            L+   E LT+PE R + ++  ++  +     NT + +    +++ DC +   +     G 
Sbjct: 3508 LISEFERLTHPEHRFKDYMETVKTMMKSTPINTSEIQKLGVEIYNDCFNPHTVR----GD 3563

Query: 1176 YNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESIKDLAENLAKSQRNLQTGKISLGSL 997
            YN KFAK++     +    +GSKL  MD KK  E + D++  +AK+ +   T  + L   
Sbjct: 3564 YNLKFAKEWDHHYSQHFSKDGSKLAKMDVKKLVELVADMSGKMAKTMKPSSTATMKLKDF 3623

Query: 996  SKWMAEYDESGVFVRQVAXXXXXXXXXXXXXXXXXXXIPGHYTGFKKPDPSSHVKLISFD 817
            S W+ E+D S                           +PG Y G  KP P  H+K+ SFD
Sbjct: 3624 SNWLVEFDRSNQLTE--------------------IELPGQYHGTSKPQPEIHIKISSFD 3663

Query: 816  QTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLRLDQRIEQLFGVMNEILSRDIVCSR 637
              L  + S ++PK +K+ GSDE+DY FL+KGGEDLRLDQRI+QLF VMNEIL RD   S+
Sbjct: 3664 PNLLVMGSLRKPKRIKIHGSDEQDYPFLIKGGEDLRLDQRIQQLFFVMNEILKRDPATSK 3723

Query: 636  KKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDGL-MHKMPSVRHATSKQEKNTPAGL 460
            + L ++TY VVP++ + G+IE++ DT  + ++I D + +H+        + +  N     
Sbjct: 3724 RGLHIKTYQVVPMTGKVGIIEWLNDTKPLKEIIEDQMAVHQ--------NVERSNVSLSR 3775

Query: 459  LSSLRTQYQDWILKKGG----SSAKLSESYTNMYKKASAEDIKKEMEILTSQLPWDALKT 292
            + + +  + +WI   G     ++      Y  M+  +   D  K+ E    ++P + L+ 
Sbjct: 3776 MEAYKI-HNEWINSFGKYIKMANPPAGPLYQQMFMHSDRADAIKKQEKQHDKVPANLLQN 3834

Query: 291  GISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDFGYS 112
            GI  +++S ES+L +R+ F RSL+  SIC Y+ G+GDRHL NFL+  K G LI IDFG++
Sbjct: 3835 GIWAISSSPESYLFIRNSFARSLATFSICSYIIGIGDRHLENFLISQKDGILIGIDFGHA 3894

Query: 111  FGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLL 7
            FGT    LP+PEL+PFRLT QFT+ L+PLD+VGLL
Sbjct: 3895 FGTATQFLPIPELMPFRLTRQFTSFLMPLDSVGLL 3929


>ref|XP_640856.2| DNA-dependent protein kinase  subunit [Dictyostelium discoideum AX4]
            gi|122086252|sp|Q54UC0.2|PRKDC_DICDI RecName:
            Full=DNA-dependent protein kinase catalytic subunit;
            Short=DNA-PK catalytic subunit; Short=DNA-PKcs
            gi|90970659|gb|EAL66880.2| DNA-dependent protein kinase
            subunit [Dictyostelium discoideum AX4]
          Length = 4299

 Score =  475 bits (1222), Expect = e-131
 Identities = 306/967 (31%), Positives = 493/967 (50%), Gaps = 54/967 (5%)
 Frame = -1

Query: 2739 ELASLAVVTDQFDLAVFYLKKFYESFRMKWSSVHPLATASKHILLKKLQQVVELDEYVE- 2563
            ELA L V     + A +Y+ KFY++F+ +WSS HPLA  S+H +L+ LQ++VE++E++  
Sbjct: 3239 ELAFLEVTRSDHNKASYYVSKFYQAFKHQWSSSHPLAIESRHRILQPLQKIVEVEEFLNL 3298

Query: 2562 HITKERNEASLTRLFNVWHKRWPSPQFDDVEAWDDVLQNRLLYFEKTQQLVGRQLLKEDG 2383
              T   N   L  L   W  R+P+ + DD+  WDD++  R +  EK  +         D 
Sbjct: 3299 TSTPIINTLKLDTLLTQWKSRFPT-KLDDIMVWDDLIFYRSVLLEKIYERFSS--FTSDK 3355

Query: 2382 DFDKQRVVDLDFEKANIFYEAARGLILQGSYDASQGYMNQYMAAIEGSNKKEKLNFDFFN 2203
              D++    L  E+A ++++ ++G    G+   S+ Y  Q + +     K   L F    
Sbjct: 3356 SSDEKVKSTLIQERAILYHKMSKGARKLGNIVVSEIYFRQAVKSYP-KTKDNDLAFPLVT 3414

Query: 2202 TLVKLRCLQADRESTIDAFEAVTMLQQVRDYVTSTARKALYQNQTKWRAGLKMLEGDV-- 2029
            +L+ + C +A   ++    E +    +   ++ S   +    N  +      M+ GD+  
Sbjct: 3415 SLIDIYCTKA--RNSPSPIETLDRFVKALKFIESKKDEESIINSNENLQKYLMMHGDIFW 3472

Query: 2028 -----------TSKLATFSLKSLSENSVSPKEIENCVSLFGSAYAAYSKLF--------- 1909
                       T  + +F   SL  N  S         LF S +  YS+           
Sbjct: 3473 DIYQLDKKLGSTLVIDSFKKNSLPINLTSIPINSLKDELFNSTFKCYSESIKLHQKSTNL 3532

Query: 1908 --------------------SEVSSADPFVHDEFFTSR-KIAKAYIKFAFFCDELL---- 1804
                                S  SS+ P + +E    + K   A++KFA FCD +L    
Sbjct: 3533 LNTTSSSPSLSISSSSSPYSSTSSSSQPKLSNEILIEKTKTKSAHLKFANFCDNILKDKI 3592

Query: 1803 -NCTKQTHWNQDLLLKLKKGDVSASLPPSSEYPVLVVRYIMKAIQMDINLQIQH--GIAR 1633
               T  T +N++++      D++ S          V+   ++AI+ +I   +     +  
Sbjct: 3593 SQQTTPTQFNEEVI------DLATS----------VIVSTLEAIKEEIPGSVDKFPRLLE 3636

Query: 1632 VLTLLGHYSNTHSEFVHQQNGIPCWLFIAWIPQILAVLEKEEGAVLVSVLEDIAHLYPQA 1453
            +LT    YS    EF  + + IPCW+FI WI Q+   L+  +G +++ +L +IA  YPQA
Sbjct: 3637 ILTQFEQYSVIAREFKSRVSTIPCWMFIRWISQMFPYLDLPQGPLILPILLEIAKWYPQA 3696

Query: 1452 LYFPYNASKSDFGPIGQERTSKISALLNNPLLNGLVHALEDLTYPEQRLQYWLSHIRNCI 1273
            +YFP+  S   FGP+ ++ ++ +   L NPLL+ LV   + LT+PE R + ++  +++ I
Sbjct: 3697 IYFPFKISSEQFGPLAKKISAPLEKELINPLLDTLVIEFQRLTHPEHRFKDYMEEMKSLI 3756

Query: 1272 SVGNTKDAEATFHQMFEDCLDSEAMSSRKSGTYNEKFAKDYSKKVLKALGMNGSKLQSMD 1093
                 KD  A   ++  +  D     S  SG YN KFAK++    L   G + +KL  MD
Sbjct: 3757 K-ATPKDLNA-IAKLNNEIYDDSFNPSTVSGDYNLKFAKEHEASYLSNFGKDSTKLARMD 3814

Query: 1092 EKKYAESIKDLAENLAKSQRNLQTGKISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXXX 913
            +KK+ E   +++ N+ K+ +   T  + L   S W+A++D S                  
Sbjct: 3815 QKKFLEIFAEMSGNMNKNMKPNSTASMKLKDFSGWLADFDRSN----------------- 3857

Query: 912  XXXXXXXXXIPGHYTGFKKPDPSSHVKLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFL 733
                     IPG Y G  KP P +HV + SFD  +  + S ++PK +K+ G+DE DY FL
Sbjct: 3858 -YQTSHQMEIPGQYDGIGKPQPETHVTISSFDTNVLVMGSLRKPKRVKIHGNDELDYPFL 3916

Query: 732  VKGGEDLRLDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSV 553
            +KGGEDLRLDQRI+QLFG+MNEIL RD  C+++ L++ TY VVP++ + G+IE++ DT  
Sbjct: 3917 IKGGEDLRLDQRIQQLFGIMNEILKRDTACNKRSLNVTTYQVVPMTSKVGIIEWLNDTKP 3976

Query: 552  IDDVIRDGLMHKMPSVRHATSKQEKNTPAGLLSSLRTQYQDWI---LKKGGSSAKLSESY 382
            + +++ + L H++ + R        N     L S +  + DWI    K    ++ +   Y
Sbjct: 3977 LREILEEQLAHQLKTPR-------SNVSISKLESTK-YHNDWINSFAKYLKPNSPVGPLY 4028

Query: 381  TNMYKKASAEDIKKEMEILTSQLPWDALKTGISKLATSAESFLALRSQFTRSLSALSICC 202
              M+  A+ +D  K++E   S++P + L+ GI  L++S ES+L +R+ F RSL++ S+C 
Sbjct: 4029 QQMFIHATRDDCAKKLEKQHSKVPENLLQNGIWSLSSSPESYLFIRNSFARSLASFSVCS 4088

Query: 201  YVAGVGDRHLSNFLLDTKRGTLIPIDFGYSFGTGVILLPVPELIPFRLTPQFTNVLLPLD 22
            YV G+GDRHL NFL+  + G LI IDFG++FGT    LP+PEL+PFRLT QFT+ L PLD
Sbjct: 4089 YVIGIGDRHLENFLISQRDGRLIGIDFGHAFGTATQFLPIPELMPFRLTRQFTSFLRPLD 4148

Query: 21   AVGLLRN 1
            +VGLL +
Sbjct: 4149 SVGLLNH 4155


>ref|XP_003286510.1| DNA-dependent protein kinase subunit [Dictyostelium purpureum]
            gi|325083491|gb|EGC36942.1| DNA-dependent protein kinase
            subunit [Dictyostelium purpureum]
          Length = 4168

 Score =  471 bits (1211), Expect = e-129
 Identities = 310/977 (31%), Positives = 509/977 (52%), Gaps = 64/977 (6%)
 Frame = -1

Query: 2739 ELASLAVVTDQFDLAVFYLKKFYESFRMKWSSVHPLATASKHILLKKLQQVVELDEYVEH 2560
            ELA L V     + A +Y+ KFY++F+ +WSS HPLA AS+H +L+ LQ++VE++E++ +
Sbjct: 3110 ELAFLEVTRSDHNKAAYYVSKFYQNFKQQWSSSHPLAIASRHRILQPLQKIVEVEEFL-N 3168

Query: 2559 ITKERNEAS--LTRLFNVWHKRWPSPQFDDVEAWDDVLQNRLLYFEKTQQLVGRQLL-KE 2389
            +T  +N ++  L  L + W KR+PS Q DD+  WDD++  R +  EK  +        K 
Sbjct: 3169 LTSNQNISNNQLDHLLSQWKKRFPSKQ-DDIMVWDDLVFYRSVLLEKIYERFSTFCTDKS 3227

Query: 2388 DGDFDKQRVVDLDFEKANIFYEAARGLILQGSYDASQGYMNQYMAAIEGSNKKEKLNFDF 2209
              D  K +++    E+A ++++ ++G    G+   S+ Y    + +     K+  L F  
Sbjct: 3228 SEDRVKSKLIQ---ERAILYHKMSKGARKLGNIVVSETYFRLSVKSYP-KTKENDLAFPL 3283

Query: 2208 FNTLVKLRCLQADRES----TIDAFEAVTMLQQVRDYVTSTARKALYQNQTKWRAGLKML 2041
             ++L+ + C++A   +    T+D F  V  L+ +       +  ++ +N  K+     M+
Sbjct: 3284 VSSLLDIYCIKARTSASPIETLDRF--VKALKFIESKKNEESIVSINENLQKYL----MM 3337

Query: 2040 EGDV-------TSKLATFSLKSLSENSVSPKEIENCV------SLFGSAYAAYSK----- 1915
             GD+         KL +  +    + +  P  + +         LF   ++ YS+     
Sbjct: 3338 HGDIFWDIYQLDKKLGSKFVNESFKKNELPSHLTSIPINKLKDELFNLTFSCYSESIKLN 3397

Query: 1914 ----------------LFSEVSSADPFVHDEFFTSR----------KIAKAYIKFAFFCD 1813
                            L S+V++     +    TS           KI  A++KFA FCD
Sbjct: 3398 EINKNKQSNQTGSSQQLSSQVNNPQSNNNPSSQTSEINNFNLIEKTKIKSAHLKFANFCD 3457

Query: 1812 ELLNCTKQTHWNQDLLLKLKKGDVSASLPPSSEYPVLVVRYIMKAIQMDINLQIQH--GI 1639
             +L    Q++  Q     + +  ++ +L         V++  ++AI+ ++   I     +
Sbjct: 3458 NILKDKLQSNNGQ-----INEETLNLALT--------VIKSTLEAIREELPGSIDKFPRL 3504

Query: 1638 ARVLTLLGHYSNTHSEFVHQQNGIPCWLFIAWIPQILAVLEKEEGAVLVSVLEDIAHLYP 1459
              +LT    Y   + EF    + IPCW+FI WI Q+   L+  +G +++ +L DIA  YP
Sbjct: 3505 LEILTQFEQYQQVNKEFTEHVSNIPCWMFIRWISQMFPYLDLPQGPLILPLLLDIAKYYP 3564

Query: 1458 QALYFPYNASKSDFGPIGQERTSKISALLNNPLLNGLVHALEDLTYPEQRLQYWLSHIRN 1279
            QA+YFPY  S   FGP+ ++ + ++   L++PLL+ LV     LT+PE R + ++  +++
Sbjct: 3565 QAIYFPYKISSEQFGPMAKKLSVQLEKELSDPLLDRLVIEFARLTHPEHRFKDFMEEMKS 3624

Query: 1278 CISVGNTKDAEATF---HQMFEDCLDSEAMSSRKSGTYNEKFAKDYSKKVLKALGMNGSK 1108
             I    TKD  A      ++++D  + + +S    G YN KFAK++  K LK  G + + 
Sbjct: 3625 LIK-SPTKDISAISILNSEIYDDSFNPKTVS----GDYNIKFAKEWEDKYLKYYGKDATI 3679

Query: 1107 LQSMDEKKYAESIKDLAENLAKSQRNLQTGKISLGSLSKWMAEYDESGVFVRQVAXXXXX 928
            L  MD+KK+ E   +++  + K+ R   T  + L   S W+ E+D S     +       
Sbjct: 3680 LSRMDQKKFLEHFAEMSSEMNKNMRPTSTATMKLKDFSYWLTEFDRSNYPTSK------- 3732

Query: 927  XXXXXXXXXXXXXXIPGHYTGFKKPDPSSHVKLISFDQTLTCLSSKQRPKILKMRGSDEK 748
                          IPG Y GF KP P +HV + SFD  +  + S ++PK +K+ G+DE+
Sbjct: 3733 -----------QLEIPGQYNGFGKPQPETHVTISSFDSNILVMGSLRKPKRIKIHGNDER 3781

Query: 747  DYKFLVKGGEDLRLDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGVIEFI 568
            DY FL+KGGEDLRLDQRI+QLF +MNEIL RD  C+++ L + TY V+P++ + G+IE+I
Sbjct: 3782 DYPFLIKGGEDLRLDQRIQQLFMIMNEILKRDNSCNKRGLKVTTYQVIPMTSKVGIIEWI 3841

Query: 567  EDTSVIDDVIRD--GLMHKMPSVRHATSKQEKNTPAGLLSSLRTQYQDWILKKGGSSAKL 394
             DT  + +++ D   +  K P    + SK E              +  WI     S AK 
Sbjct: 3842 NDTRPLREILEDQIAIQTKTPRSNVSISKLEAT----------NIHNTWI----QSFAKY 3887

Query: 393  SE------SYTNMYKKASAEDIKKEMEILTSQLPWDALKTGISKLATSAESFLALRSQFT 232
            S+       Y  M+  A+ ++  K+ E   +++P + L+ GI  L++S ES+L +R+ F 
Sbjct: 3888 SKINSPGPLYQQMFIHANRDNAVKKFEKQIAKVPENLLQNGIWALSSSPESYLFIRNSFA 3947

Query: 231  RSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDFGYSFGTGVILLPVPELIPFRLTP 52
            RSL+  S+C YV G+GDRHL NFL+  + GTLI IDFG++FGT    LP+PEL+PFRLT 
Sbjct: 3948 RSLATFSVCSYVIGIGDRHLENFLISQRDGTLIGIDFGHAFGTATQFLPIPELMPFRLTR 4007

Query: 51   QFTNVLLPLDAVGLLRN 1
            QFT+ L PLD+VGLL +
Sbjct: 4008 QFTSFLRPLDSVGLLNH 4024


>ref|XP_004350354.1| DNA-dependent protein kinase subunit [Dictyostelium fasciculatum]
            gi|328865264|gb|EGG13650.1| DNA-dependent protein kinase
            subunit [Dictyostelium fasciculatum]
          Length = 3111

 Score =  466 bits (1200), Expect = e-128
 Identities = 311/984 (31%), Positives = 505/984 (51%), Gaps = 73/984 (7%)
 Frame = -1

Query: 2739 ELASLAVVTDQFDLAVFYLKKFYESFRMKWSSVHPLATASKHILLKKLQQVVELDEYVEH 2560
            ELA L +    ++ + +Y++KFY+ FR KW+S HPLA +S+H LL+ +Q+++E++E++  
Sbjct: 2049 ELAFLEITRSDYNKSHYYIQKFYQRFREKWASTHPLAISSRHRLLQPIQKMIEIEEFLSL 2108

Query: 2559 I-------TKERNEASLTRLF--------------------------------------- 2518
            +       +    +  +T+LF                                       
Sbjct: 2109 VHPKSTFSSSGSTDTDMTKLFMKGLMADKVVTPGRTFVSKDELATNVANSALNIKHMESL 2168

Query: 2517 -NVWHKRWPSPQFDDVEAWDDVLQNRLLYFEKTQQLVGRQLLKEDGDFDKQRVVDLDF-E 2344
             N+W KR+PS + DDV  WDDV+  R +  EK  +   R +  ++ +  +  + +L   E
Sbjct: 2169 VNLWKKRYPS-RLDDVVVWDDVVSYRSVLLEKIYE---RFMSSQNDEHIESSIKNLLIQE 2224

Query: 2343 KANIFYEAARGLILQGSYDASQGYMNQYMAAIEGSNKKEKLNFDFFNTLVKLRCLQADRE 2164
            +A ++++ ++G    G+   S+ Y    + +     K+  L F   ++L+K+ CL+A   
Sbjct: 2225 RAELYHQMSKGARKLGNIIVSESYFRLAVKSYP-KTKENDLAFPLVSSLIKIYCLKAKNS 2283

Query: 2163 ST----IDAFEAVTMLQQVRDYVTSTARKALYQNQTKWRA-------GLKMLEGDVTSKL 2017
            ST    +D F  V  L+ V         K    NQ K+          L  LEG + + +
Sbjct: 2284 STPQECLDRF--VKALKFVVSKSNEETIKQSIDNQQKYERLHGDILWELYQLEGQLGADV 2341

Query: 2016 ATFSLK--SLSENSVSPKEIENCVS-LFGSAYAAYSKLFSEVSSADPFVHDEFFTSRKIA 1846
               SLK  S+S  S+S        S LF  AY  Y+      +           ++  ++
Sbjct: 2342 VQDSLKKNSMSIPSLSLAPAAKVSSELFNMAYRCYNDSIQLHTKQQQ-------SNNSVS 2394

Query: 1845 K-AYIKFAFFCDELLNCTKQTHWNQDLLLKLKKGDVSASLPPSSEYPVLVVRYIMKAIQM 1669
            K AY++FA FCD +L   ++T+ N+       K D ++ L  S      VV   + AI+ 
Sbjct: 2395 KGAYLQFANFCDNVL--AQRTNANE-------KSDEASVLASS------VVNAALTAIKE 2439

Query: 1668 DINLQIQHGIARVLTLLGHYSNTHSEFVHQQNGIPCWLFIAWIPQILAVLEKEEGAVLVS 1489
            +I   I+    R+L ++  Y +T ++F      IPCW+FI W+ QI   L+  +G +++S
Sbjct: 2440 EIPGAIEK-FPRLLEIISQYESTANDFKENIKTIPCWMFIRWMSQIFPYLDLPQGPLVIS 2498

Query: 1488 VLEDIAHLYPQALYFPYNASKSDFGPIGQERTSKISALLNNPLLNGLVHALEDLTYPEQR 1309
            +L  IA  YPQA+YFPY  S   FG IGQ+ +  +  +L + LL+     LE LT+PE R
Sbjct: 2499 ILVKIAQYYPQAIYFPYKISSEQFGRIGQKVSQPLDLILKDSLLDTFTLELERLTHPEHR 2558

Query: 1308 LQYWLSHIRNCISVG--NTKDAEATFHQMFEDCLDSEAMSSRKSGTYNEKFAKDYSKKVL 1135
             + ++  ++  +     +T        +++ DC + + +S    G YN+KF+K++    +
Sbjct: 2559 FKDYMETVKQILKQTPIDTSSLVKLNTEIYNDCFNHKTVS----GDYNKKFSKEWEAIYI 2614

Query: 1134 KALGMNGSKLQSMDEKKYAESIKDLAENLAKSQRNLQTGKISLGSLSKWMAEYDESGVFV 955
               G++GSKL  MD +K+ E + D+   + K+ +   T  + L   S W+AE+D+S    
Sbjct: 2615 GHFGIDGSKLIKMDGRKFVEVVTDMTIKMNKNMKPTSTASMKLKDFSSWLAEFDKSNYL- 2673

Query: 954  RQVAXXXXXXXXXXXXXXXXXXXIPGHYTGFKKPDPSSHVKLISFDQTLTCLSSKQRPKI 775
                                   IPG Y G+ KP P  H+K+ SFD  +  + S ++PK 
Sbjct: 2674 -------------------NNIEIPGQYNGYGKPQPELHIKVSSFDANILVMGSLRKPKR 2714

Query: 774  LKMRGSDEKDYKFLVKGGEDLRLDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVPIS 595
            +K+ GSDE++Y FLVKGGEDLRLDQR++QLF VMN+I+++D   S++ L + TY VVP++
Sbjct: 2715 VKIHGSDEQNYPFLVKGGEDLRLDQRVQQLFHVMNDIMAKDTATSQRNLKIATYHVVPMT 2774

Query: 594  KQCGVIEFIEDTSVIDDVIRD--GLMHKMPSVRHATSKQEKNTPAGLLSSLRTQYQDWI- 424
             + G+I+++ DT  + +++ +   +  K+   + + S+ E +            + DWI 
Sbjct: 2775 SKVGIIQWLLDTKPLKEILEEQMAIHQKVDRSQVSLSRMEASKI----------HSDWIQ 2824

Query: 423  -----LKKGGSSAKLSESYTNMYKKASAEDIKKEMEILTSQLPWDALKTGISKLATSAES 259
                 LK  G        Y  M+  A+A+D   + E   +++P   L+ GI  LA S E+
Sbjct: 2825 TFAKYLKTSGPPPP-GPLYHQMFIHATAKDAIDKQERQHARIPATLLQKGIWSLAASPEA 2883

Query: 258  FLALRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDFGYSFGTGVILLPVP 79
            +L +RS F RSL+  SI  YV G+GDRHL NFL+  + G LI IDFG++FGT    LP+P
Sbjct: 2884 YLFIRSSFARSLATFSIGSYVIGIGDRHLENFLISQRNGILIGIDFGHAFGTATQFLPIP 2943

Query: 78   ELIPFRLTPQFTNVLLPLDAVGLL 7
            EL+PFRLT QFT+ L PLDAVGLL
Sbjct: 2944 ELMPFRLTRQFTSFLKPLDAVGLL 2967


>ref|XP_002965996.1| hypothetical protein SELMODRAFT_84321 [Selaginella moellendorffii]
            gi|300166810|gb|EFJ33416.1| hypothetical protein
            SELMODRAFT_84321 [Selaginella moellendorffii]
          Length = 524

 Score =  439 bits (1130), Expect = e-120
 Identities = 221/398 (55%), Positives = 288/398 (72%)
 Frame = -1

Query: 1194 SRKSGTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESIKDLAENLAKSQRNLQTGK 1015
            +R++G YN KFA+DYSK V+KALG +GSKL  MDEKK+A +I  +  +L K+ ++L  GK
Sbjct: 5    TRQAGEYNVKFARDYSKPVVKALGEDGSKLLQMDEKKFATAIAGVLTSLQKAIKDLPGGK 64

Query: 1014 ISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXXXXXXXXXXXXIPGHYTGFKKPDPSSHV 835
            +SL S SKWMA +D+                            IPG Y G + PD SSH+
Sbjct: 65   LSLASFSKWMANFDQP---------------RGRGSSSDDLIEIPGQYDGLQCPDVSSHI 109

Query: 834  KLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLRLDQRIEQLFGVMNEILSR 655
             L+ FD+TL  LSSKQRPKIL MRGSDEK+YKF+VKGGEDLRLDQRIEQLF  MN +L  
Sbjct: 110  TLVGFDETLISLSSKQRPKILTMRGSDEKEYKFIVKGGEDLRLDQRIEQLFAKMNSVLRE 169

Query: 654  DIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDGLMHKMPSVRHATSKQEKN 475
            D  C++++LS+RTYAV+P+S+QCG+++F+++T V+DDVI+DG+  ++ + +       K 
Sbjct: 170  DGACAKRELSMRTYAVIPVSQQCGLLQFVDNTCVLDDVIKDGVAQQLAAAKR------KE 223

Query: 474  TPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAEDIKKEMEILTSQLPWDALK 295
                LL  LR QY  W+ KKGGS + + + Y N+Y K  A +++  M  L +Q+PWDALK
Sbjct: 224  KAGDLLVELRNQYHQWVEKKGGSKS-VHDCYKNLYTKVKAGEMEARMNALVAQVPWDALK 282

Query: 294  TGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDFGY 115
            TG+ K  +SAESFLA+RSQF RSLS +SIC Y+AGVGDRHL+N L+D + G+L+PIDFGY
Sbjct: 283  TGLYKRTSSAESFLAMRSQFARSLSVMSICGYIAGVGDRHLANTLIDMQTGSLVPIDFGY 342

Query: 114  SFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLLRN 1
            SFGTGVILLPVPELIPFRLTPQ TNVLLPLD++GLL+N
Sbjct: 343  SFGTGVILLPVPELIPFRLTPQLTNVLLPLDSLGLLKN 380


>ref|XP_002989230.1| hypothetical protein SELMODRAFT_129513 [Selaginella moellendorffii]
            gi|300142973|gb|EFJ09668.1| hypothetical protein
            SELMODRAFT_129513 [Selaginella moellendorffii]
          Length = 524

 Score =  439 bits (1128), Expect = e-120
 Identities = 221/398 (55%), Positives = 288/398 (72%)
 Frame = -1

Query: 1194 SRKSGTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESIKDLAENLAKSQRNLQTGK 1015
            +R++G YN KFA+DYSK V+KALG +GSKL  MDEKK+A +I  +  +L K+ ++L  GK
Sbjct: 5    TRQAGEYNVKFARDYSKPVVKALGEDGSKLLQMDEKKFATAIAGVLTSLQKAIKDLPGGK 64

Query: 1014 ISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXXXXXXXXXXXXIPGHYTGFKKPDPSSHV 835
            +SL S SKWMA +D+                            IPG Y G + PD SSH+
Sbjct: 65   LSLASFSKWMANFDQP---------------RGRGSSSDDLIEIPGQYDGLQCPDVSSHI 109

Query: 834  KLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLRLDQRIEQLFGVMNEILSR 655
             L+ FD+TL  LSSKQRPKIL MRGSDEK+YKF+VKGGEDLRLDQRIEQLF  MN +L  
Sbjct: 110  TLVGFDETLIGLSSKQRPKILTMRGSDEKEYKFIVKGGEDLRLDQRIEQLFAKMNSVLRE 169

Query: 654  DIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDGLMHKMPSVRHATSKQEKN 475
            D  C++++LS+RTYAV+P+S+QCG+++F+++T V+DDVI+DG+  ++ + +       K 
Sbjct: 170  DGACAKRELSMRTYAVIPVSQQCGLLQFVDNTCVLDDVIKDGVAQQLAAAKR------KE 223

Query: 474  TPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAEDIKKEMEILTSQLPWDALK 295
                LL  LR QY  W+ KKGGS + + + Y N+Y K  A +++  M  L +Q+PWDALK
Sbjct: 224  KAGDLLVELRNQYHQWVEKKGGSKS-VHDCYKNLYTKVKAGEMEARMNALVAQVPWDALK 282

Query: 294  TGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDFGY 115
            TG+ K  +SAESFLA+RSQF RSLS +SIC Y+AGVGDRHL+N L+D + G+L+PIDFGY
Sbjct: 283  TGLYKRTSSAESFLAMRSQFARSLSVMSICGYIAGVGDRHLANTLIDMQTGSLVPIDFGY 342

Query: 114  SFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLLRN 1
            SFGTGVILLPVPELIPFRLTPQ TNVLLPLD++GLL+N
Sbjct: 343  SFGTGVILLPVPELIPFRLTPQLTNVLLPLDSLGLLKN 380


>ref|XP_004454094.1| PREDICTED: DNA-dependent protein kinase catalytic subunit [Dasypus
            novemcinctus]
          Length = 4124

 Score =  382 bits (980), Expect = e-103
 Identities = 277/962 (28%), Positives = 471/962 (48%), Gaps = 51/962 (5%)
 Frame = -1

Query: 2739 ELASLAVVTDQFDLAVFYLKKFYESFRMKWSSVHPLATASKHILLKKLQQVVELDEYVEH 2560
            EL+ L ++ D FD A +Y++   + F   +SS+  L   S+   L+ +Q + E+ E+++ 
Sbjct: 3085 ELSLLYILQDDFDRAKYYIQNGIQIFMQNYSSIDVLLHRSRLTKLQSVQVLTEVQEFIDF 3144

Query: 2559 ITKERNEAS---LTRLFNVWHKRWPSPQFDDVEAWDDVLQNRLLYFEKTQQ----LVGRQ 2401
            I+K+ N +S   L RL   W  R+P  + D +  WDD++ NR  +  K ++         
Sbjct: 3145 ISKQGNLSSKVPLKRLLKSWTNRYPDAKMDPMNIWDDIITNRCFFLSKIEEKFTLTTDDH 3204

Query: 2400 LLKEDGDFDKQRVVDLDFEKANIFYEAARGLILQGSYDA-SQGYMNQYMAAIEGSNKKEK 2224
             +  DG+  ++  +    + +++       + ++    A  Q   +  M  ++  +K+ K
Sbjct: 3205 SMNVDGESSEKMEMQEKEDISSLIKSCKFSMKMKMIESARKQNSFSLAMKLLKELHKESK 3264

Query: 2223 LNFDFFNTLVKLRC----LQADRESTID----AFEAVTMLQQV--------------RDY 2110
               D+    V   C     ++  ++ ID      + V++L++               +D 
Sbjct: 3265 TRDDWLVKWVHSYCRLSHCRSQSQNQIDQILTVLKTVSLLEESSSSYLSKNILAFCDQDI 3324

Query: 2109 VTSTARKALYQNQTKWRAGLKMLEGDVTSKLATFSLKSLSENSVSPKEIENCVSLFGSAY 1930
            +  T  + +    +   A L  +E   T ++ T S  S SEN+      E  ++      
Sbjct: 3325 LLGTTYRVIANALSSEPAYLGQIEESKTRRILTLSGSS-SENA------EKVIA------ 3371

Query: 1929 AAYSKLFSEVSSADPFVHDEFFTSR-------KIAKAYIKFAFFCDELLNCTKQTHWNQD 1771
              Y K F  +S A   V +E             +  AY+    FCD          W+  
Sbjct: 3372 GLYEKAFHYLSKAVRTVEEEIQNPTWDQVHLAGMIDAYMTLVDFCD----------WH-- 3419

Query: 1770 LLLKLKKGDVSASLPPSSE---YPVLVVRYIMKAIQMDINLQIQHGIARVLTLLGHY-SN 1603
                L+KG+ + S+  S+E   YP LVV  ++KA++++ N + +    R+L ++  Y   
Sbjct: 3420 ----LRKGEENVSVIDSAELQTYPALVVDKMLKALKLNSN-EARLKFPRLLQIIEQYPEE 3474

Query: 1602 THSEFVHQQNGIPCWLFIAWIPQILAVLEKEEGAVLVSVLEDIAHLYPQALYFPYNASKS 1423
            T S    + + IPCW FI WI Q++A+L+KEE   +   +E+IA  YPQA+ +P+  S  
Sbjct: 3475 TLSLMTKEMSSIPCWQFIGWISQLVALLDKEEAVAVQHTVEEIADSYPQAIVYPFIISSE 3534

Query: 1422 DF-------GPIGQERTSKISALLNNP-LLNGLVHALEDLTYPEQRLQYWLSHIRNCISV 1267
             +       G   +E  ++I + L++  ++   ++ALE L+ PE   + W + I+  +  
Sbjct: 3535 SYSFKDTSLGHKNKEFVARIKSKLDHGGVIQDFINALEQLSNPEMLFKDWANDIKVELEK 3594

Query: 1266 G--NTKDAEATFHQMFEDCLDSEAMSSRKSGTYNEKFAKDYSKKVLKALGMNGSKLQSMD 1093
               N K+ E  + +M+    D +A      GT+  KF + + K+  K  G  GSKL  M 
Sbjct: 3595 TPVNKKNIEKMYERMYATLGDPKAQGL---GTFRRKFVQAFGKEFDKHFGKGGSKLPGMK 3651

Query: 1092 EKKYAESIKDLAENLAKSQRNLQTGKISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXXX 913
               ++    ++A +L      +     +L   S WM+++     F+R             
Sbjct: 3652 PCDFS----NIANSLCNKMSEVSKPPGNLKECSPWMSDFKVE--FLRN------------ 3693

Query: 912  XXXXXXXXXIPGHYTGFKKPDPSSHVKLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFL 733
                     IPG Y G  KP P  H ++  FD+ +  + S +RPK + +RG DE++Y FL
Sbjct: 3694 ------ELEIPGQYDGKGKPLPEYHARISGFDERIKVMPSVRRPKRIIIRGHDEREYPFL 3747

Query: 732  VKGGEDLRLDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSV 553
            VKGGEDLR DQRIEQLF VMN ILS+D  CS++ + L+TY V+P++ + G+IE+IE+T  
Sbjct: 3748 VKGGEDLRQDQRIEQLFEVMNVILSQDPACSQRSMQLKTYQVIPMTTRLGLIEWIENTLT 3807

Query: 552  IDDVIRDGLMHKMPSVRHATSKQEKNTPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNM 373
            + +++   +           +++EK        + + +Y+DW+ K  G       +Y  M
Sbjct: 3808 LKELLLSSM-----------TQEEKTAYMSDPKAPQFEYRDWLTKMSGKRG--VAAYMPM 3854

Query: 372  YKKASAEDIKKEMEILTSQLPWDALKTGISKLATSAESFLALRSQFTRSLSALSICCYVA 193
            YK AS  +         S++P D LK    K++   E+FLALRS F  S + + I  ++ 
Sbjct: 3855 YKGASRTETVTSFRKRESKVPADLLKRAFVKMSVGPEAFLALRSHFASSHALMCISHWIL 3914

Query: 192  GVGDRHLSNFLLDTKRGTLIPIDFGYSFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVG 13
            G+GDRHLSNFL++ + G+L  IDFG++FG+    LPVPEL+PFRLT QF +++LP+   G
Sbjct: 3915 GIGDRHLSNFLVNVETGSLAGIDFGHAFGSATQFLPVPELMPFRLTRQFVSLMLPMREAG 3974

Query: 12   LL 7
            LL
Sbjct: 3975 LL 3976


>ref|NP_001157330.1| DNA-dependent protein kinase catalytic subunit [Equus caballus]
          Length = 4134

 Score =  382 bits (980), Expect = e-103
 Identities = 272/953 (28%), Positives = 457/953 (47%), Gaps = 42/953 (4%)
 Frame = -1

Query: 2739 ELASLAVVTDQFDLAVFYLKKFYESFRMKWSSVHPLATASKHILLKKLQQVVELDEYVEH 2560
            EL+ L ++ D  D A +Y++     F   +SS+  L   S+   L+ LQ ++E+ E++  
Sbjct: 3092 ELSLLYILQDDVDRAKYYIENCIRIFMQSYSSIDVLLERSRLTKLQSLQTLIEIQEFISF 3151

Query: 2559 ITKERNEAS---LTRLFNVWHKRWPSPQFDDVEAWDDVLQNRLLYFEKTQQLV----GRQ 2401
            I+K+ N +S   L RL   W  R+P  + D +  WDD++ NR  +  K ++ +       
Sbjct: 3152 ISKQGNLSSQIPLKRLLKTWTNRYPDAKMDPMNIWDDIITNRCFFLSKIEEKLTLPPDDH 3211

Query: 2400 LLKEDGDFDKQRVVDLDFEKANIF--YEAARGLILQGSYDASQGYMNQYMAA--IEGSNK 2233
             +  DGD D    + +  ++ +I+   ++ +  +     ++++   N  +A   ++  +K
Sbjct: 3212 SMNTDGDEDSSDRMKVQEQEEDIYSLIKSCKFSMKMKMIESARKQKNFSLAMKLLKELHK 3271

Query: 2232 KEKLNFDFFNTLVKLRC-LQADRESTIDAFEAVTMLQQVRDYVTSTARKALYQN------ 2074
            + K   D+    V+  C L   R  T +  E +  + +    +       L +N      
Sbjct: 3272 ESKTRDDWLVKWVQSYCRLSHSRSQTQNRPEQILTVLKTVSLLDENTSSYLSKNIPVSRD 3331

Query: 2073 -----QTKWRAGLKMLEGDVTSKLATFSLKSLSENSVSPKEIENCVSLFGSAYAAYSKLF 1909
                  T +R     L  D T        K+     +S   +EN   +    Y       
Sbjct: 3332 HNILLGTTYRIIANALSSDPTCLAEIGESKARRILELSGSSLENAEEVIAGLYQRVLHHL 3391

Query: 1908 SEV-----SSADPFVHDEFFTSRKIAKAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKGD 1744
            SE        A PF   +   +  +  AY+    FCD+                +L+K +
Sbjct: 3392 SEAVRIAEEEAQPFTRGQE-PAVGVIDAYMTLVDFCDQ----------------QLRKEE 3434

Query: 1743 VSASLPPSSE---YPVLVVRYIMKAIQMDINLQIQHGIARVLTLLGHY-SNTHSEFVHQQ 1576
             S+S+  S +   YP LVV  ++KA+++  N + +    R+L ++  Y   T S    + 
Sbjct: 3435 ESSSVTESVQLQMYPALVVDKMLKALRLHSN-EARLKFPRLLQIIEQYPEETLSLMTKEI 3493

Query: 1575 NGIPCWLFIAWIPQILAVLEKEEGAVLVSVLEDIAHLYPQALYFPYNASKSDF------- 1417
            + IPCW FI WI  ++A+L+KEE   +   +E+IA  YPQA+ +P+  S   +       
Sbjct: 3494 SSIPCWQFIGWISHMVALLDKEEAVAVHRTVEEIADNYPQAMVYPFIISSESYSFKDTST 3553

Query: 1416 GPIGQERTSKISALLNNP-LLNGLVHALEDLTYPEQRLQYWLSHIRNCISVG--NTKDAE 1246
            G   +E   +I   L+   ++   ++ALE L++PE   + W   I+  +     N K+ E
Sbjct: 3554 GYKNKEFVERIKIKLDQGGVIQDFINALEQLSHPEMLFKDWTDDIKVELEKNPVNRKNIE 3613

Query: 1245 ATFHQMFEDCLDSEAMSSRKSGTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESIK 1066
              + +M+    D +A      G +  +F + + K+  K  G  GSKL  M  ++++    
Sbjct: 3614 KMYEKMYATLGDPQAPGL---GAFRRRFIQAFGKEFDKHFGRGGSKLPGMKPREFS---- 3666

Query: 1065 DLAENLAKSQRNLQTGKISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXXXXXXXXXXXX 886
            D+  +L      +     +L   S WM+++     F+R                      
Sbjct: 3667 DITNSLFSKMCEVSKPPGNLKECSPWMSDFKVE--FLRS------------------ELE 3706

Query: 885  IPGHYTGFKKPDPSSHVKLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLRL 706
            IPG Y G  KP P  H ++  FD+ +  ++S ++PK + +RG DE++Y FLVKGGEDLR 
Sbjct: 3707 IPGQYDGKGKPVPEYHARIAGFDERIKVMASMRKPKRIIIRGHDEREYPFLVKGGEDLRQ 3766

Query: 705  DQRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDGL 526
            DQRIEQLF VMN ILS+D  CS++ + L+TY V+P++ + G+IE+IE+T  + ++    L
Sbjct: 3767 DQRIEQLFEVMNVILSQDATCSQRSMQLKTYQVIPMTSRLGLIEWIENTFTLKEL----L 3822

Query: 525  MHKMPSVRHATSKQEKNTPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAEDI 346
            +  M     A    +   P         +Y+DW+ K  G       +Y  MYK AS  + 
Sbjct: 3823 LSNMSQEEKAACTSDPKAPP-------FEYRDWLTKMSGKCD--VGAYMLMYKGASRTET 3873

Query: 345  KKEMEILTSQLPWDALKTGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLSN 166
                    S++P D LK    K++TS E+FL LRS F RS + + I  ++ G+GDRHL+N
Sbjct: 3874 VTSFRKRESKVPADLLKRAFVKMSTSPEAFLTLRSHFARSHALICISHWILGIGDRHLNN 3933

Query: 165  FLLDTKRGTLIPIDFGYSFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLL 7
            FL+  + G +I IDFG++FG+    LPVPEL+PFRLT QF N++LP+   G++
Sbjct: 3934 FLVSMETGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGVM 3986


>gb|AAL40980.1| DNA-dependent protein kinase catalytic subunit [Equus caballus]
          Length = 4106

 Score =  381 bits (978), Expect = e-102
 Identities = 274/958 (28%), Positives = 452/958 (47%), Gaps = 47/958 (4%)
 Frame = -1

Query: 2739 ELASLAVVTDQFDLAVFYLKKFYESFRMKWSSVHPLATASKHILLKKLQQVVELDEYVEH 2560
            EL+ L ++ D  D A +Y++     F   +SS+  L   S+   L+ LQ ++E+ E++  
Sbjct: 3064 ELSLLYILQDDVDRAKYYIENCIRIFMQSYSSIDVLLERSRLTKLQSLQALIEIQEFISF 3123

Query: 2559 ITKERNEAS---LTRLFNVWHKRWPSPQFDDVEAWDDVLQNRLLYFEKTQQLV----GRQ 2401
            I K+ N +S   L RL   W  R+P  + D +  WDD++ NR  +  K ++ +       
Sbjct: 3124 IRKQGNLSSQIPLKRLLKTWTNRYPDAKMDPMNIWDDIITNRCFFLSKIEEKLTIPPDDH 3183

Query: 2400 LLKEDGDFDKQRVVDLDFEKANIFYEAARGLILQGSYDAS---------QGYMNQYMAAI 2248
             +  DGD D    + +  ++ +I+      LI  G +            Q   +  M  +
Sbjct: 3184 SMNTDGDEDSSDRMKVQEQEEDIY-----SLIKSGKFSMKMKMIESARKQKNFSLAMKLL 3238

Query: 2247 EGSNKKEKLNFDFFNTLVKLRC-LQADRESTIDAFEAVTMLQQVRDYVTSTARKALYQN- 2074
            +  +K+ K   D+    V+  C L   R  T +  E +  + +    +       L +N 
Sbjct: 3239 KELHKESKTRDDWLVKWVQSYCRLSHSRSQTQNRPEQILTVLKTVSLLDENTSSYLSKNI 3298

Query: 2073 ----------QTKWRAGLKMLEGDVTSKLATFSLKSLSENSVSPKEIENCVSLFGSAYAA 1924
                       T +R     L  D T        K+     +S   +EN   +    Y  
Sbjct: 3299 PVSRDHNILLGTTYRIIANALSSDPTCLAEIGESKARRILELSGSSLENAEEVIAGLYQR 3358

Query: 1923 YSKLFSEV-----SSADPFVHDEFFTSRKIAKAYIKFAFFCDELLNCTKQTHWNQDLLLK 1759
                 SE        A PF   +   +  +  AY+    FCD+                +
Sbjct: 3359 VLHHLSEAVRIAEEEAQPFTRGQE-PAVGVIDAYMTLVDFCDQ----------------Q 3401

Query: 1758 LKKGDVSASLPPSSE---YPVLVVRYIMKAIQMDINLQIQHGIARVLTLLGHY-SNTHSE 1591
            L+K + S+S+  S +   YP LVV  ++KA+++D N + +    R+L ++  Y   T S 
Sbjct: 3402 LRKEEESSSVTESVQLQMYPALVVDKMLKALRLDSN-EARLKFPRLLQIIERYPEETLSL 3460

Query: 1590 FVHQQNGIPCWLFIAWIPQILAVLEKEEGAVLVSVLEDIAHLYPQALYFPYNASKSDF-- 1417
               + + IPCW FI WI  ++A+L+KEE   +   +E+IA  YPQA+ +P+  S   +  
Sbjct: 3461 MTKEISSIPCWQFIGWISHMVALLDKEEAVAVHRTVEEIADNYPQAMVYPFIISSESYSF 3520

Query: 1416 -----GPIGQERTSKISALLNNP-LLNGLVHALEDLTYPEQRLQYWLSHIRNCISVG--N 1261
                 G   +E   +I   L+   ++   ++ALE L++PE   + W   I+  +     N
Sbjct: 3521 KDTSTGYKNKEFVERIKIKLDQGGVIQDFINALEQLSHPEMLFKDWTDDIKVELEKNPVN 3580

Query: 1260 TKDAEATFHQMFEDCLDSEAMSSRKSGTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKY 1081
             K+ E  + +M+    D +A      G +  +  + + K+  K  G  GSKL  M  +++
Sbjct: 3581 RKNIEKMYEKMYATLGDPQAPGL---GAFRRRCIQGFGKEFDKHFGRGGSKLPGMKSREF 3637

Query: 1080 AESIKDLAENLAKSQRNLQTGKISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXXXXXXX 901
            +    D+  +L      +     +L   S WM+++     F+R                 
Sbjct: 3638 S----DITNSLFSKMCEVSKPPGNLKECSPWMSDFKVE--FLRS---------------- 3675

Query: 900  XXXXXIPGHYTGFKKPDPSSHVKLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGG 721
                 IPG Y G  KP P  H ++  FD+ +  ++S ++PK + +RG DE++Y FLVKGG
Sbjct: 3676 --ELEIPGQYDGKGKPVPEYHARIAGFDERIKVMASMRKPKRIIIRGHDEREYPFLVKGG 3733

Query: 720  EDLRLDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDV 541
            EDLR DQRIEQLF VMN ILS+D  CS++ + L+TY V+P++ + G+IE+IE+T  + ++
Sbjct: 3734 EDLRQDQRIEQLFEVMNVILSQDATCSQRSMQLKTYQVIPMTSRLGLIEWIENTFTLKEL 3793

Query: 540  IRDGLMHKMPSVRHATSKQEKNTPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKA 361
                L+  M     A   ++   P         +Y+DW+ K  G       +Y  MYK A
Sbjct: 3794 ----LLSNMSQEEKAACTRDPKAPP-------FEYRDWLTKMSGKCD--VGAYMLMYKGA 3840

Query: 360  SAEDIKKEMEILTSQLPWDALKTGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGD 181
            S  +         S++P D LK    K++TS E+FL LRS F  S + + I  ++ G+GD
Sbjct: 3841 SRTETVTSFRKRESKVPADLLKRAFVKMSTSPEAFLTLRSHFAGSHALICISHWIPGIGD 3900

Query: 180  RHLSNFLLDTKRGTLIPIDFGYSFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLL 7
            RHL+NFL+  + G +I IDFG++FG+    LPVPEL+PFRLT QF N++LP+   G++
Sbjct: 3901 RHLNNFLVSMETGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGVM 3958


>gb|EHH28470.1| DNA-dependent protein kinase catalytic subunit [Macaca mulatta]
          Length = 4128

 Score =  379 bits (974), Expect = e-102
 Identities = 276/954 (28%), Positives = 469/954 (49%), Gaps = 43/954 (4%)
 Frame = -1

Query: 2739 ELASLAVVTDQFDLAVFYLKKFYESFRMKWSSVHPLATASKHILLKKLQQVVELDEYVEH 2560
            EL+ L ++ D  D A +Y++   +SF   +SS+  L   S+   L+ +Q + E+ E++  
Sbjct: 3085 ELSLLYLLQDDIDRARYYIQNGIQSFMQNYSSIDVLLHRSRLTKLQSVQALTEIQEFISF 3144

Query: 2559 ITKERNEAS---LTRLFNVWHKRWPSPQFDDVEAWDDVLQNRLLYFEKTQQLV------G 2407
            I+K+ N +S   L RL N W  R+P  + D +  WDDV+ NR  +  K ++ +       
Sbjct: 3145 ISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWDDVITNRCFFLSKIEEKLTPLPEDN 3204

Query: 2406 RQLLKEDGDFDKQRVVDLDFEKANIFYEAARGLILQGSYDAS--QGYMNQYMAAIEGSNK 2233
               + EDGD   +  V    E  +    + +  +     D++  Q   +  M  ++  +K
Sbjct: 3205 SMNVDEDGDPSDRMDVQEQEEDISSLIRSCKFSMKMKMVDSARKQNNFSLAMKLLKELHK 3264

Query: 2232 KEKLNFDFFNTLVKLRCL--------QADRESTIDAFEAVTMLQQ--VRDYVTSTARKAL 2083
            + K   D+  + V+  C         Q   E  +   + V++L +  V  Y++     + 
Sbjct: 3265 ESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTVLKTVSLLDENNVSSYLSKNILASR 3324

Query: 2082 YQN---QTKWRAGLKMLEGDVT--SKLATFSLKSLSENSVSPKEIENCVSLFGSAYAAYS 1918
             QN    T +R     L  +    +++     + + E S S  E    V + G    A+ 
Sbjct: 3325 DQNILLGTTYRIIANALSSEPACLAEIEEDKARRILELSGSSSEDSEKV-IVGLYQRAFQ 3383

Query: 1917 KLFSEVSSADPFVHDEFFTSRKIA---KAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKG 1747
             L   V +A+       ++ R  A    AY+  A FCD+                +L+K 
Sbjct: 3384 HLSEAVQAAEEEAQPPSWSCRPAAGVIDAYMTLADFCDQ----------------QLRKE 3427

Query: 1746 DVSASLPPSSE---YPVLVVRYIMKAIQMDINLQIQHGIARVLTLLGHY-SNTHSEFVHQ 1579
            + +AS+  S+E   YP LVV  ++KA++++ N + +    R+L ++  Y   T S    +
Sbjct: 3428 EENASVTDSAELQAYPALVVEKMLKALKLNSN-EARLKFPRLLQIIERYPEETLSLMTKE 3486

Query: 1578 QNGIPCWLFIAWIPQILAVLEKEEGAVLVSVLEDIAHLYPQALYFPYNASKSDF------ 1417
             + +PCW FI WI  ++A+L+K++   +   +E+I   YPQA+ +P+  S   +      
Sbjct: 3487 ISSVPCWQFIGWISHMVALLDKDQAIAVQHTVEEITDNYPQAIVYPFIISSESYSFKDTS 3546

Query: 1416 -GPIGQERTSKISALLNNP-LLNGLVHALEDLTYPEQRLQYWLSHIRNCISVG--NTKDA 1249
             G   +E  ++I + L+   ++   ++AL+ L+ PE   + W + +R  ++    N K+ 
Sbjct: 3547 TGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTPVNKKNI 3606

Query: 1248 EATFHQMFEDCLDSEAMSSRKSGTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESI 1069
            E  + +M+    D +A      G +  KF + + K+  K  G  GSKL  M    +    
Sbjct: 3607 EKMYERMYAALGDPKAPGL---GAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDF---- 3659

Query: 1068 KDLAENLAKSQRNLQTGKISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXXXXXXXXXXX 889
             D+   L            +L   S WM+++     F+R                     
Sbjct: 3660 NDITNMLLLKMNKDSKPPGNLKECSPWMSDFKVE--FLRN------------------EL 3699

Query: 888  XIPGHYTGFKKPDPSSHVKLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLR 709
             IPG Y G  KP P  HV++  FD+ +T ++S +RPK + +RG +E+++ FLVKGGEDLR
Sbjct: 3700 EIPGQYDGRGKPLPEYHVRIAGFDERVTVMASMRRPKRIIIRGHNEREHPFLVKGGEDLR 3759

Query: 708  LDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDG 529
             DQR+EQLF VMN IL++D  CS++ L LRTY+VVP++ + G+IE++E+T  + D+    
Sbjct: 3760 QDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDL---- 3815

Query: 528  LMHKMPSVRHATSKQEKNTPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAED 349
            L++ M     A    +   P         +Y+DW+ K  G       +Y  MYK A+  +
Sbjct: 3816 LLNTMSQEEKAAYLSDPKAPL-------CEYRDWLTKMSGKHD--VGAYMLMYKGANRTE 3866

Query: 348  IKKEMEILTSQLPWDALKTGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLS 169
                     S++P D LK    +++TS E+FLALRS F  S + + I  ++ G+GDRHL+
Sbjct: 3867 TITSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLN 3926

Query: 168  NFLLDTKRGTLIPIDFGYSFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLL 7
            NF++  + G +I IDFG++FG+    LPVPEL+PFRLT QF N++LP+  +GL+
Sbjct: 3927 NFMVAMETGGMIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKEMGLM 3980


>ref|XP_005563337.1| PREDICTED: DNA-dependent protein kinase catalytic subunit isoform X2
            [Macaca fascicularis]
          Length = 4128

 Score =  379 bits (973), Expect = e-102
 Identities = 276/954 (28%), Positives = 469/954 (49%), Gaps = 43/954 (4%)
 Frame = -1

Query: 2739 ELASLAVVTDQFDLAVFYLKKFYESFRMKWSSVHPLATASKHILLKKLQQVVELDEYVEH 2560
            EL+ L ++ D  D A +Y++   +SF   +SS+  L   S+   L+ +Q + E+ E++  
Sbjct: 3085 ELSLLYLLQDDIDRARYYIQNGIQSFMQNYSSIDVLLHRSRLTKLQSVQALTEIQEFISF 3144

Query: 2559 ITKERNEAS---LTRLFNVWHKRWPSPQFDDVEAWDDVLQNRLLYFEKTQQLV------G 2407
            I+K+ N +S   L RL N W  R+P  + D +  WDDV+ NR  +  K ++ +       
Sbjct: 3145 ISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWDDVITNRCFFLSKIEEKLTPLPEDN 3204

Query: 2406 RQLLKEDGDFDKQRVVDLDFEKANIFYEAARGLILQGSYDAS--QGYMNQYMAAIEGSNK 2233
               + EDGD   +  V    E  +    + +  +     D++  Q   +  M  ++  +K
Sbjct: 3205 SMNVDEDGDPSDRMDVQEQEEDISSLIRSCKFSMKMKMVDSARKQNNFSLAMKLLKELHK 3264

Query: 2232 KEKLNFDFFNTLVKLRCL--------QADRESTIDAFEAVTMLQQ--VRDYVTSTARKAL 2083
            + K   D+  + V+  C         Q   E  +   + V++L +  V  Y++     + 
Sbjct: 3265 ESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTVLKTVSLLDENNVSSYLSKNILASR 3324

Query: 2082 YQN---QTKWRAGLKMLEGDVT--SKLATFSLKSLSENSVSPKEIENCVSLFGSAYAAYS 1918
             QN    T +R     L  +    +++     + + E S S  E    V + G    A+ 
Sbjct: 3325 DQNILLGTTYRIIANALSSEPACLAEIEEDKARRILELSGSSSEDSEKV-IAGLYQRAFQ 3383

Query: 1917 KLFSEVSSADPFVHDEFFTSRKIA---KAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKG 1747
             L   V +A+       ++ R  A    AY+  A FCD+                +L+K 
Sbjct: 3384 HLSEAVQAAEEEAQPPSWSCRPAAGVIDAYMTLADFCDQ----------------QLRKE 3427

Query: 1746 DVSASLPPSSE---YPVLVVRYIMKAIQMDINLQIQHGIARVLTLLGHY-SNTHSEFVHQ 1579
            + +AS+  S+E   YP LVV  ++KA++++ N + +    R+L ++  Y   T S    +
Sbjct: 3428 EENASVTDSAELQAYPALVVEKMLKALKLNSN-EARLKFPRLLQIIERYPEETLSLMTKE 3486

Query: 1578 QNGIPCWLFIAWIPQILAVLEKEEGAVLVSVLEDIAHLYPQALYFPYNASKSDF------ 1417
             + +PCW FI WI  ++A+L+K++   +   +E+I   YPQA+ +P+  S   +      
Sbjct: 3487 ISSVPCWQFIGWISHMVALLDKDQAIAVQHTVEEITDNYPQAIVYPFIISSESYSFKDTS 3546

Query: 1416 -GPIGQERTSKISALLNNP-LLNGLVHALEDLTYPEQRLQYWLSHIRNCISVG--NTKDA 1249
             G   +E  ++I + L+   ++   ++AL+ L+ PE   + W + +R  ++    N K+ 
Sbjct: 3547 TGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTPVNKKNI 3606

Query: 1248 EATFHQMFEDCLDSEAMSSRKSGTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESI 1069
            E  + +M+    D +A      G +  KF + + K+  K  G  GSKL  M    +    
Sbjct: 3607 EKMYERMYAALGDPKAPGL---GAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDF---- 3659

Query: 1068 KDLAENLAKSQRNLQTGKISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXXXXXXXXXXX 889
             D+   L            +L   S WM+++     F+R                     
Sbjct: 3660 NDITNMLLLKMNKDSKPPGNLKECSPWMSDFKVE--FLRN------------------EL 3699

Query: 888  XIPGHYTGFKKPDPSSHVKLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLR 709
             IPG Y G  KP P  HV++  FD+ +T ++S +RPK + +RG +E+++ FLVKGGEDLR
Sbjct: 3700 EIPGQYDGRGKPLPEYHVRIAGFDERVTVMASMRRPKRIIIRGHNEREHPFLVKGGEDLR 3759

Query: 708  LDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDG 529
             DQR+EQLF VMN IL++D  CS++ L LRTY+VVP++ + G+IE++E+T  + D+    
Sbjct: 3760 QDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDL---- 3815

Query: 528  LMHKMPSVRHATSKQEKNTPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAED 349
            L++ M     A    +   P         +Y+DW+ K  G       +Y  MYK A+  +
Sbjct: 3816 LLNTMSQEEKAAYLSDPKAPL-------CEYRDWLTKMSGKHD--VGAYMLMYKGANRTE 3866

Query: 348  IKKEMEILTSQLPWDALKTGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLS 169
                     S++P D LK    +++TS E+FLALRS F  S + + I  ++ G+GDRHL+
Sbjct: 3867 TITSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLN 3926

Query: 168  NFLLDTKRGTLIPIDFGYSFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLL 7
            NF++  + G +I IDFG++FG+    LPVPEL+PFRLT QF N++LP+  +GL+
Sbjct: 3927 NFMVAMETGGMIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKEMGLM 3980


>ref|XP_005563336.1| PREDICTED: DNA-dependent protein kinase catalytic subunit isoform X1
            [Macaca fascicularis]
          Length = 4129

 Score =  379 bits (973), Expect = e-102
 Identities = 276/954 (28%), Positives = 469/954 (49%), Gaps = 43/954 (4%)
 Frame = -1

Query: 2739 ELASLAVVTDQFDLAVFYLKKFYESFRMKWSSVHPLATASKHILLKKLQQVVELDEYVEH 2560
            EL+ L ++ D  D A +Y++   +SF   +SS+  L   S+   L+ +Q + E+ E++  
Sbjct: 3086 ELSLLYLLQDDIDRARYYIQNGIQSFMQNYSSIDVLLHRSRLTKLQSVQALTEIQEFISF 3145

Query: 2559 ITKERNEAS---LTRLFNVWHKRWPSPQFDDVEAWDDVLQNRLLYFEKTQQLV------G 2407
            I+K+ N +S   L RL N W  R+P  + D +  WDDV+ NR  +  K ++ +       
Sbjct: 3146 ISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWDDVITNRCFFLSKIEEKLTPLPEDN 3205

Query: 2406 RQLLKEDGDFDKQRVVDLDFEKANIFYEAARGLILQGSYDAS--QGYMNQYMAAIEGSNK 2233
               + EDGD   +  V    E  +    + +  +     D++  Q   +  M  ++  +K
Sbjct: 3206 SMNVDEDGDPSDRMDVQEQEEDISSLIRSCKFSMKMKMVDSARKQNNFSLAMKLLKELHK 3265

Query: 2232 KEKLNFDFFNTLVKLRCL--------QADRESTIDAFEAVTMLQQ--VRDYVTSTARKAL 2083
            + K   D+  + V+  C         Q   E  +   + V++L +  V  Y++     + 
Sbjct: 3266 ESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTVLKTVSLLDENNVSSYLSKNILASR 3325

Query: 2082 YQN---QTKWRAGLKMLEGDVT--SKLATFSLKSLSENSVSPKEIENCVSLFGSAYAAYS 1918
             QN    T +R     L  +    +++     + + E S S  E    V + G    A+ 
Sbjct: 3326 DQNILLGTTYRIIANALSSEPACLAEIEEDKARRILELSGSSSEDSEKV-IAGLYQRAFQ 3384

Query: 1917 KLFSEVSSADPFVHDEFFTSRKIA---KAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKG 1747
             L   V +A+       ++ R  A    AY+  A FCD+                +L+K 
Sbjct: 3385 HLSEAVQAAEEEAQPPSWSCRPAAGVIDAYMTLADFCDQ----------------QLRKE 3428

Query: 1746 DVSASLPPSSE---YPVLVVRYIMKAIQMDINLQIQHGIARVLTLLGHY-SNTHSEFVHQ 1579
            + +AS+  S+E   YP LVV  ++KA++++ N + +    R+L ++  Y   T S    +
Sbjct: 3429 EENASVTDSAELQAYPALVVEKMLKALKLNSN-EARLKFPRLLQIIERYPEETLSLMTKE 3487

Query: 1578 QNGIPCWLFIAWIPQILAVLEKEEGAVLVSVLEDIAHLYPQALYFPYNASKSDF------ 1417
             + +PCW FI WI  ++A+L+K++   +   +E+I   YPQA+ +P+  S   +      
Sbjct: 3488 ISSVPCWQFIGWISHMVALLDKDQAIAVQHTVEEITDNYPQAIVYPFIISSESYSFKDTS 3547

Query: 1416 -GPIGQERTSKISALLNNP-LLNGLVHALEDLTYPEQRLQYWLSHIRNCISVG--NTKDA 1249
             G   +E  ++I + L+   ++   ++AL+ L+ PE   + W + +R  ++    N K+ 
Sbjct: 3548 TGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTPVNKKNI 3607

Query: 1248 EATFHQMFEDCLDSEAMSSRKSGTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESI 1069
            E  + +M+    D +A      G +  KF + + K+  K  G  GSKL  M    +    
Sbjct: 3608 EKMYERMYAALGDPKAPGL---GAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDF---- 3660

Query: 1068 KDLAENLAKSQRNLQTGKISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXXXXXXXXXXX 889
             D+   L            +L   S WM+++     F+R                     
Sbjct: 3661 NDITNMLLLKMNKDSKPPGNLKECSPWMSDFKVE--FLRN------------------EL 3700

Query: 888  XIPGHYTGFKKPDPSSHVKLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLR 709
             IPG Y G  KP P  HV++  FD+ +T ++S +RPK + +RG +E+++ FLVKGGEDLR
Sbjct: 3701 EIPGQYDGRGKPLPEYHVRIAGFDERVTVMASMRRPKRIIIRGHNEREHPFLVKGGEDLR 3760

Query: 708  LDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDG 529
             DQR+EQLF VMN IL++D  CS++ L LRTY+VVP++ + G+IE++E+T  + D+    
Sbjct: 3761 QDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDL---- 3816

Query: 528  LMHKMPSVRHATSKQEKNTPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAED 349
            L++ M     A    +   P         +Y+DW+ K  G       +Y  MYK A+  +
Sbjct: 3817 LLNTMSQEEKAAYLSDPKAPL-------CEYRDWLTKMSGKHD--VGAYMLMYKGANRTE 3867

Query: 348  IKKEMEILTSQLPWDALKTGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLS 169
                     S++P D LK    +++TS E+FLALRS F  S + + I  ++ G+GDRHL+
Sbjct: 3868 TITSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLN 3927

Query: 168  NFLLDTKRGTLIPIDFGYSFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLL 7
            NF++  + G +I IDFG++FG+    LPVPEL+PFRLT QF N++LP+  +GL+
Sbjct: 3928 NFMVAMETGGMIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKEMGLM 3981


>ref|XP_001100610.2| PREDICTED: DNA-dependent protein kinase catalytic subunit-like
            isoform 2 [Macaca mulatta]
          Length = 4099

 Score =  379 bits (973), Expect = e-102
 Identities = 276/954 (28%), Positives = 469/954 (49%), Gaps = 43/954 (4%)
 Frame = -1

Query: 2739 ELASLAVVTDQFDLAVFYLKKFYESFRMKWSSVHPLATASKHILLKKLQQVVELDEYVEH 2560
            EL+ L ++ D  D A +Y++   +SF   +SS+  L   S+   L+ +Q + E+ E++  
Sbjct: 3056 ELSLLYLLQDDIDRARYYIQNGIQSFMQNYSSIDVLLHRSRLTKLQSVQALTEIQEFISF 3115

Query: 2559 ITKERNEAS---LTRLFNVWHKRWPSPQFDDVEAWDDVLQNRLLYFEKTQQLV------G 2407
            I+K+ N +S   L RL N W  R+P  + D +  WDDV+ NR  +  K ++ +       
Sbjct: 3116 ISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWDDVITNRCFFLSKIEEKLTPLPEDN 3175

Query: 2406 RQLLKEDGDFDKQRVVDLDFEKANIFYEAARGLILQGSYDAS--QGYMNQYMAAIEGSNK 2233
               + EDGD   +  V    E  +    + +  +     D++  Q   +  M  ++  +K
Sbjct: 3176 SMNVDEDGDPSDRMDVQEQEEDISSLIRSCKFSMKMKMVDSARKQNNFSLAMKLLKELHK 3235

Query: 2232 KEKLNFDFFNTLVKLRCL--------QADRESTIDAFEAVTMLQQ--VRDYVTSTARKAL 2083
            + K   D+  + V+  C         Q   E  +   + V++L +  V  Y++     + 
Sbjct: 3236 ESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTVLKTVSLLDENNVSSYLSKNILASR 3295

Query: 2082 YQN---QTKWRAGLKMLEGDVT--SKLATFSLKSLSENSVSPKEIENCVSLFGSAYAAYS 1918
             QN    T +R     L  +    +++     + + E S S  E    V + G    A+ 
Sbjct: 3296 DQNILLGTTYRIIANALSSEPACLAEIEEDKARRILELSGSSSEDSEKV-IAGLYQRAFQ 3354

Query: 1917 KLFSEVSSADPFVHDEFFTSRKIA---KAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKG 1747
             L   V +A+       ++ R  A    AY+  A FCD+                +L+K 
Sbjct: 3355 HLSEAVQAAEEEAQPPSWSCRPAAGVIDAYMTLADFCDQ----------------QLRKE 3398

Query: 1746 DVSASLPPSSE---YPVLVVRYIMKAIQMDINLQIQHGIARVLTLLGHY-SNTHSEFVHQ 1579
            + +AS+  S+E   YP LVV  ++KA++++ N + +    R+L ++  Y   T S    +
Sbjct: 3399 EENASVTDSAELQAYPALVVEKMLKALKLNSN-EARLKFPRLLQIIERYPEETLSLMTKE 3457

Query: 1578 QNGIPCWLFIAWIPQILAVLEKEEGAVLVSVLEDIAHLYPQALYFPYNASKSDF------ 1417
             + +PCW FI WI  ++A+L+K++   +   +E+I   YPQA+ +P+  S   +      
Sbjct: 3458 ISSVPCWQFIGWISHMVALLDKDQAIAVQHTVEEITDNYPQAIVYPFIISSESYSFKDTS 3517

Query: 1416 -GPIGQERTSKISALLNNP-LLNGLVHALEDLTYPEQRLQYWLSHIRNCISVG--NTKDA 1249
             G   +E  ++I + L+   ++   ++AL+ L+ PE   + W + +R  ++    N K+ 
Sbjct: 3518 TGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTPVNKKNI 3577

Query: 1248 EATFHQMFEDCLDSEAMSSRKSGTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESI 1069
            E  + +M+    D +A      G +  KF + + K+  K  G  GSKL  M    +    
Sbjct: 3578 EKMYERMYAALGDPKAPGL---GAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDF---- 3630

Query: 1068 KDLAENLAKSQRNLQTGKISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXXXXXXXXXXX 889
             D+   L            +L   S WM+++     F+R                     
Sbjct: 3631 NDITNMLLLKMNKDSKPPGNLKECSPWMSDFKVE--FLRN------------------EL 3670

Query: 888  XIPGHYTGFKKPDPSSHVKLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLR 709
             IPG Y G  KP P  HV++  FD+ +T ++S +RPK + +RG +E+++ FLVKGGEDLR
Sbjct: 3671 EIPGQYDGRGKPLPEYHVRIAGFDERVTVMASMRRPKRIIIRGHNEREHPFLVKGGEDLR 3730

Query: 708  LDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDG 529
             DQR+EQLF VMN IL++D  CS++ L LRTY+VVP++ + G+IE++E+T  + D+    
Sbjct: 3731 QDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDL---- 3786

Query: 528  LMHKMPSVRHATSKQEKNTPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAED 349
            L++ M     A    +   P         +Y+DW+ K  G       +Y  MYK A+  +
Sbjct: 3787 LLNTMSQEEKAAYLSDPKAPL-------CEYRDWLTKMSGKHD--VGAYMLMYKGANRTE 3837

Query: 348  IKKEMEILTSQLPWDALKTGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLS 169
                     S++P D LK    +++TS E+FLALRS F  S + + I  ++ G+GDRHL+
Sbjct: 3838 TITSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLN 3897

Query: 168  NFLLDTKRGTLIPIDFGYSFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLL 7
            NF++  + G +I IDFG++FG+    LPVPEL+PFRLT QF N++LP+  +GL+
Sbjct: 3898 NFMVAMETGGMIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKEMGLM 3951


>ref|XP_003902769.1| PREDICTED: DNA-dependent protein kinase catalytic subunit, partial
            [Papio anubis]
          Length = 4076

 Score =  379 bits (972), Expect = e-102
 Identities = 277/954 (29%), Positives = 468/954 (49%), Gaps = 43/954 (4%)
 Frame = -1

Query: 2739 ELASLAVVTDQFDLAVFYLKKFYESFRMKWSSVHPLATASKHILLKKLQQVVELDEYVEH 2560
            EL+ L ++ D  D A +Y++   +SF   +SS+  L   S+   L+ +Q + E+ E++  
Sbjct: 3033 ELSLLYLLQDDIDRARYYIQNGIQSFMQNYSSIDVLLHRSRLTKLQSVQALTEIQEFISF 3092

Query: 2559 ITKERNEAS---LTRLFNVWHKRWPSPQFDDVEAWDDVLQNRLLYFEKTQQLV------G 2407
            I+K+ N +S   L RL N W  R+P  + D +  WDDV+ NR  +  K ++ +       
Sbjct: 3093 ISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWDDVITNRCFFLSKIEEKLTPLPEDN 3152

Query: 2406 RQLLKEDGDFDKQRVVDLDFEKANIFYEAARGLILQGSYDAS--QGYMNQYMAAIEGSNK 2233
               + EDGD   +  V    E  +    + +  +     D++  Q   +  M  ++  +K
Sbjct: 3153 SMNVDEDGDPSDRMDVQEQEEDISSLIRSCKFSMKMKMVDSARKQNNFSLAMKLLKELHK 3212

Query: 2232 KEKLNFDFFNTLVKLRCL--------QADRESTIDAFEAVTMLQQ--VRDYVTSTARKAL 2083
            + K   D+  + V+  C         Q   E  +   + V++L +  V  Y++     + 
Sbjct: 3213 ESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTVLKTVSLLDENNVSSYLSKNILASR 3272

Query: 2082 YQN---QTKWRAGLKMLEGDVT--SKLATFSLKSLSENSVSPKEIENCVSLFGSAYAAYS 1918
             QN    T +R     L  +    +++     + + E S S  E    V + G    A+ 
Sbjct: 3273 DQNILLGTTYRIIANALSSEPACLAEIEEDKARRILELSGSSSEDSEKV-IAGLYQRAFQ 3331

Query: 1917 KLFSEVSSADPFVHDEFFTSRKIA---KAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKG 1747
             L   V +A+       ++ R  A    AY+  A FCD+                +L+K 
Sbjct: 3332 HLSEAVQAAEEEAQPPSWSCRPAAGVIDAYMTLADFCDQ----------------QLRKE 3375

Query: 1746 DVSASLPPSSE---YPVLVVRYIMKAIQMDINLQIQHGIARVLTLLGHY-SNTHSEFVHQ 1579
            + +AS+  S+E   YP LVV  ++KA++++ N + +    R+L ++  Y   T S    +
Sbjct: 3376 EENASVTDSAELQAYPALVVEKMLKALKLNSN-EARLKFPRLLQIIERYPEETLSLMTKE 3434

Query: 1578 QNGIPCWLFIAWIPQILAVLEKEEGAVLVSVLEDIAHLYPQALYFPYNASKSDF------ 1417
             + +PCW FI WI  I+A+L+K++   +   +E+I   YPQA+ +P+  S   +      
Sbjct: 3435 ISSVPCWQFIGWISHIVALLDKDQAIAVQHTVEEITDNYPQAIVYPFIISSESYSFKDTS 3494

Query: 1416 -GPIGQERTSKISALLNNP-LLNGLVHALEDLTYPEQRLQYWLSHIRNCISVG--NTKDA 1249
             G   +E  ++I + L+   ++   ++AL+ L+ PE   + W + +R  ++    N K  
Sbjct: 3495 TGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTPVNKKII 3554

Query: 1248 EATFHQMFEDCLDSEAMSSRKSGTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESI 1069
            E  + +M+    D +A      G +  KF + + K+  K  G  GSKL  M    +    
Sbjct: 3555 EKMYERMYAALGDPKAPGL---GAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDF---- 3607

Query: 1068 KDLAENLAKSQRNLQTGKISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXXXXXXXXXXX 889
             D+   L            +L   S WM+++     F+R                     
Sbjct: 3608 NDITNMLLLKMNKDSKPPGNLKECSPWMSDFKVE--FLRN------------------EL 3647

Query: 888  XIPGHYTGFKKPDPSSHVKLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLR 709
             IPG Y G  KP P  HV++  FD+ +T ++S +RPK + +RG +E+++ FLVKGGEDLR
Sbjct: 3648 EIPGQYDGRGKPLPEYHVRIAGFDERVTVMASMRRPKRIIIRGHNEREHPFLVKGGEDLR 3707

Query: 708  LDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDG 529
             DQR+EQLF VMN IL++D  CS++ L LRTY+VVP++ + G+IE++E+T  + D+    
Sbjct: 3708 QDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDL---- 3763

Query: 528  LMHKMPSVRHATSKQEKNTPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAED 349
            L++ M     A    +   P         +Y+DW+ K  G       +Y  MYK A+  +
Sbjct: 3764 LLNTMSQEEKAAYLSDPKAPL-------CEYRDWLTKMSGKHD--VGAYMLMYKGANRTE 3814

Query: 348  IKKEMEILTSQLPWDALKTGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLS 169
                     S++P D LK    +++TS E+FLALRS F  S + + I  ++ G+GDRHL+
Sbjct: 3815 TITSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLN 3874

Query: 168  NFLLDTKRGTLIPIDFGYSFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLL 7
            NF++  + G +I IDFG++FG+    LPVPEL+PFRLT QF N++LP+  +GL+
Sbjct: 3875 NFMVAMETGGMIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKEMGLM 3928


>ref|XP_003777295.1| PREDICTED: LOW QUALITY PROTEIN: DNA-dependent protein kinase
            catalytic subunit-like, partial [Pongo abelii]
          Length = 3742

 Score =  378 bits (970), Expect = e-102
 Identities = 275/954 (28%), Positives = 469/954 (49%), Gaps = 43/954 (4%)
 Frame = -1

Query: 2739 ELASLAVVTDQFDLAVFYLKKFYESFRMKWSSVHPLATASKHILLKKLQQVVELDEYVEH 2560
            EL+ L ++ D  D A +Y++   +SF   +SS+  L   S+   L+ +Q + E+ E++  
Sbjct: 2699 ELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVLLHQSRLTKLQSVQALTEIQEFIGF 2758

Query: 2559 ITKERNEAS---LTRLFNVWHKRWPSPQFDDVEAWDDVLQNRLLYFEKTQQLV------G 2407
            I+K+ N +S   L RL N W  R+P  + D +  WDD++ NR  +  K ++ +       
Sbjct: 2759 ISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWDDIITNRCFFLSKIEEKLTPLPEDN 2818

Query: 2406 RQLLKEDGDFDKQRVVDLDFEKANIFYEAARGLILQGSYDAS--QGYMNQYMAAIEGSNK 2233
               + +DGD   +  V    E  +    + +  +     D++  Q   +  M  ++  +K
Sbjct: 2819 SMNVDQDGDSSDRMEVQEQEEDISSLIRSCKFSMKMMMIDSARKQNNFSLAMKLLKELHK 2878

Query: 2232 KEKLNFDFFNTLVKLRCL--------QADRESTIDAFEAVTMLQQ--VRDYVTSTARKAL 2083
            + K   D+  + V+  C         Q   E  +   + V++L +  V  Y++       
Sbjct: 2879 ESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTVLKTVSLLDENNVSSYLSKNILAFR 2938

Query: 2082 YQN---QTKWR--AGLKMLEGDVTSKLATFSLKSLSENSVSPKEIENCVSLFGSAYAAYS 1918
             QN    T +R  A    +E    +++     + + E S S  E    V + G    A+ 
Sbjct: 2939 DQNILLGTTYRIIANALSIEPACLAEIEEDKARRILELSGSSSEDSEKV-IAGLYQRAFQ 2997

Query: 1917 KLFSEVSSADPFVHDEFFT---SRKIAKAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKG 1747
             L   V +A+       ++   +  +  AY+  A FCD+                +L+K 
Sbjct: 2998 HLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFCDQ----------------QLRKE 3041

Query: 1746 DVSASLPPSSE---YPVLVVRYIMKAIQMDINLQIQHGIARVLTLLGHY-SNTHSEFVHQ 1579
            + +AS+  S+E   YP LVV  ++KA++++ N + +    R+L ++  Y   T S    +
Sbjct: 3042 EENASVIDSAELQAYPALVVEKMLKALKLNSN-EARLKFPRLLQIIERYPEETLSLMTKE 3100

Query: 1578 QNGIPCWLFIAWIPQILAVLEKEEGAVLVSVLEDIAHLYPQALYFPYNASKSDF------ 1417
             + IPCW FI WI  ++A+L+K++   +   +E+I   YPQA+ +P+  S   +      
Sbjct: 3101 ISSIPCWQFIGWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESYSFKDTS 3160

Query: 1416 -GPIGQERTSKISALLNNP-LLNGLVHALEDLTYPEQRLQYWLSHIRNCISVG--NTKDA 1249
             G   +E  ++I + L+   ++   ++AL+ L+ PE   + W + +R  ++    N K+ 
Sbjct: 3161 TGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTPVNKKNI 3220

Query: 1248 EATFHQMFEDCLDSEAMSSRKSGTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESI 1069
            E  + +M+    D +A      G +  KF + + K+  K  G  GSKL  M    +    
Sbjct: 3221 EKMYERMYAALGDPKAPGL---GAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDF---- 3273

Query: 1068 KDLAENLAKSQRNLQTGKISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXXXXXXXXXXX 889
             D+   L            +L   S WM+++     F+R                     
Sbjct: 3274 NDITNMLLLKMNKDSKPPGNLKECSPWMSDFKVE--FLRN------------------EL 3313

Query: 888  XIPGHYTGFKKPDPSSHVKLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLR 709
             IPG Y G  KP P  HV++  FD+ +T ++S +RPK + +RG DE+++ FLVKGGEDLR
Sbjct: 3314 EIPGQYDGRGKPLPEYHVRIAGFDERVTVMASMRRPKRIIIRGHDEREHPFLVKGGEDLR 3373

Query: 708  LDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDG 529
             DQR+EQLF VMN IL++D  CS++ L LRTY+VVP++ + G+IE++E+T  + D+    
Sbjct: 3374 QDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDL---- 3429

Query: 528  LMHKMPSVRHATSKQEKNTPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAED 349
            L++ M     A    +   P         +Y+DW+ K  G       +Y  MYK A+  +
Sbjct: 3430 LLNTMSQEEKAAYLSDPKAPP-------CEYKDWLTKMSGKHD--VGAYMLMYKGANRTE 3480

Query: 348  IKKEMEILTSQLPWDALKTGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLS 169
                     S++P D LK    +++TS E+FLALRS F  S + + I  ++ G+GDRHL+
Sbjct: 3481 TVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLN 3540

Query: 168  NFLLDTKRGTLIPIDFGYSFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLL 7
            NF++  + G++I IDFG++FG+    LPVPEL+PFRLT QF N++LP+   GL+
Sbjct: 3541 NFMVAMETGSMIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLM 3594


>gb|EHH64150.1| DNA-dependent protein kinase catalytic subunit [Macaca fascicularis]
          Length = 4128

 Score =  377 bits (969), Expect = e-101
 Identities = 274/954 (28%), Positives = 469/954 (49%), Gaps = 43/954 (4%)
 Frame = -1

Query: 2739 ELASLAVVTDQFDLAVFYLKKFYESFRMKWSSVHPLATASKHILLKKLQQVVELDEYVEH 2560
            EL+ L ++ D  D A +Y++   +SF   +SS+  L   S+   L+ +Q + E+ E++  
Sbjct: 3085 ELSLLYLLQDDIDRARYYIQNGIQSFMQNYSSIDVLLHRSRLTKLQSVQALTEIQEFISF 3144

Query: 2559 ITKERNEAS---LTRLFNVWHKRWPSPQFDDVEAWDDVLQNRLLYFEKTQQLV------G 2407
            I+K+ N +S   L RL N W  R+P  + D +  WDD++ NR  +  K ++ +       
Sbjct: 3145 ISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWDDIITNRCFFLSKIEEKLTPLPEDN 3204

Query: 2406 RQLLKEDGDFDKQRVVDLDFEKANIFYEAARGLILQGSYDAS--QGYMNQYMAAIEGSNK 2233
               + EDGD   +  +    E  +    + +  +     D++  Q   +  M  ++  +K
Sbjct: 3205 SMNVDEDGDPSDRMDMQEQEEDISSLIRSCKFSMKMKMVDSARKQNNFSLAMKLLKELHK 3264

Query: 2232 KEKLNFDFFNTLVKLRCL--------QADRESTIDAFEAVTMLQQ--VRDYVTSTARKAL 2083
            + K   D+  + V+  C         Q   E  +   + V++L +  V  Y++     + 
Sbjct: 3265 ESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTVLKTVSLLDENNVSSYLSKNILASR 3324

Query: 2082 YQN---QTKWRAGLKMLEGDVT--SKLATFSLKSLSENSVSPKEIENCVSLFGSAYAAYS 1918
             QN    T +R     L  +    +++     + + E S S  E    V + G    A+ 
Sbjct: 3325 DQNILLGTTYRIIANALSSEPACLAEIEEDKARRILELSGSSSEDSEKV-IAGLYQRAFQ 3383

Query: 1917 KLFSEVSSADPFVHDEFFTSRKIA---KAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKG 1747
             L   V +A+       ++ R  A    AY+  A FCD+                +L+K 
Sbjct: 3384 HLSEAVQAAEEEAQPPSWSCRPAAGVIDAYMTLADFCDQ----------------QLRKE 3427

Query: 1746 DVSASLPPSSE---YPVLVVRYIMKAIQMDINLQIQHGIARVLTLLGHY-SNTHSEFVHQ 1579
            + +AS+  S+E   YP LVV  ++KA++++ N + +    R+L ++  Y   T S    +
Sbjct: 3428 EENASVTDSAELQAYPALVVEKMLKALKLNSN-EARLKFPRLLQIIERYPEETLSLMTKE 3486

Query: 1578 QNGIPCWLFIAWIPQILAVLEKEEGAVLVSVLEDIAHLYPQALYFPYNASKSDF------ 1417
             + +PCW FI WI  ++A+L+K++   +   +E+I   YPQA+ +P+  S   +      
Sbjct: 3487 ISSVPCWQFIGWISHMVALLDKDQAIAVQHTVEEITDNYPQAIVYPFIISSESYSFKDTS 3546

Query: 1416 -GPIGQERTSKISALLNNP-LLNGLVHALEDLTYPEQRLQYWLSHIRNCISVG--NTKDA 1249
             G   +E  ++I + L+   ++   ++AL+ L+ PE   + W + +R  ++    N K+ 
Sbjct: 3547 TGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTPVNKKNI 3606

Query: 1248 EATFHQMFEDCLDSEAMSSRKSGTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESI 1069
            E  + +M+    D +A      G +  KF + + K+  K  G  GSKL  M    +    
Sbjct: 3607 EKMYERMYAALGDPKAPGL---GAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDF---- 3659

Query: 1068 KDLAENLAKSQRNLQTGKISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXXXXXXXXXXX 889
             D+   L            +L   S WM+++     F+R                     
Sbjct: 3660 NDITNMLLLKMNKDSKPPGNLKECSPWMSDFKVE--FLRN------------------EL 3699

Query: 888  XIPGHYTGFKKPDPSSHVKLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLR 709
             IPG Y G  KP P  HV++  FD+ +T ++S +RPK + +RG +E+++ FLVKGGEDLR
Sbjct: 3700 EIPGQYDGRGKPLPEYHVRIAGFDERVTVMASMRRPKRIIIRGHNEREHPFLVKGGEDLR 3759

Query: 708  LDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDG 529
             DQR+EQLF VMN IL++D  CS++ L LRTY+VVP++ + G+IE++E+T  + D+    
Sbjct: 3760 QDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDL---- 3815

Query: 528  LMHKMPSVRHATSKQEKNTPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAED 349
            L++ M     A    +   P         +Y+DW+ K  G       +Y  MYK A+  +
Sbjct: 3816 LLNTMSQEEKAAYLSDPKAPL-------CEYRDWLTKMSGKHD--VGAYMLMYKGANRTE 3866

Query: 348  IKKEMEILTSQLPWDALKTGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLS 169
                     S++P D LK    +++TS E+FLALRS F  S + + I  ++ G+GDRHL+
Sbjct: 3867 TITSFRKRESKVPADLLKRAFVRISTSPEAFLALRSHFASSHALICISHWILGIGDRHLN 3926

Query: 168  NFLLDTKRGTLIPIDFGYSFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLL 7
            NF++  + G +I IDFG++FG+    LPVPEL+PFRLT QF N++LP+  +GL+
Sbjct: 3927 NFMVAMETGGMIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKEMGLM 3980


>ref|NP_008835.5| DNA-dependent protein kinase catalytic subunit isoform 1 [Homo
            sapiens] gi|38258929|sp|P78527.3|PRKDC_HUMAN RecName:
            Full=DNA-dependent protein kinase catalytic subunit;
            Short=DNA-PK catalytic subunit; Short=DNA-PKcs; AltName:
            Full=DNPK1; AltName: Full=p460 gi|13570017|gb|AAB39925.5|
            DNA-dependent protein kinase catalytic subunit [Homo
            sapiens] gi|32140473|gb|AAP69525.1| protein kinase,
            DNA-activated, catalytic polypeptide [Homo sapiens]
            gi|119607087|gb|EAW86681.1| protein kinase,
            DNA-activated, catalytic polypeptide, isoform CRA_b [Homo
            sapiens]
          Length = 4128

 Score =  375 bits (963), Expect = e-101
 Identities = 276/957 (28%), Positives = 473/957 (49%), Gaps = 46/957 (4%)
 Frame = -1

Query: 2739 ELASLAVVTDQFDLAVFYLKKFYESFRMKWSSVHPLATASKHILLKKLQQVVELDEYVEH 2560
            EL+ L ++ D  D A +Y++   +SF   +SS+  L   S+   L+ +Q + E+ E++  
Sbjct: 3085 ELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVLLHQSRLTKLQSVQALTEIQEFISF 3144

Query: 2559 ITKERNEAS---LTRLFNVWHKRWPSPQFDDVEAWDDVLQNRLLYFEKTQQLV------G 2407
            I+K+ N +S   L RL N W  R+P  + D +  WDD++ NR  +  K ++ +       
Sbjct: 3145 ISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWDDIITNRCFFLSKIEEKLTPLPEDN 3204

Query: 2406 RQLLKEDGDFDKQRVVDLDFEKANIFYEAARGLILQGSYDAS--QGYMNQYMAAIEGSNK 2233
               + +DGD   +  V    E  +    + +  +     D++  Q   +  M  ++  +K
Sbjct: 3205 SMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKMKMIDSARKQNNFSLAMKLLKELHK 3264

Query: 2232 KEKLNFDFFNTLVKLRCL--------QADRESTIDAFEAVTMLQQ--VRDYVTSTARKAL 2083
            + K   D+  + V+  C         Q   E  +   + V++L +  V  Y++       
Sbjct: 3265 ESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTVLKTVSLLDENNVSSYLSKNILAFR 3324

Query: 2082 YQN---QTKWRAGLKMLEGDVT--SKLATFSLKSLSENSVSPKEIENCVSLFGSAYAAYS 1918
             QN    T +R     L  +    +++     + + E S S  E    V + G    A+ 
Sbjct: 3325 DQNILLGTTYRIIANALSSEPACLAEIEEDKARRILELSGSSSEDSEKV-IAGLYQRAFQ 3383

Query: 1917 KLFSEVSSADPFVHDEFFT---SRKIAKAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKG 1747
             L   V +A+       ++   +  +  AY+  A FCD+                +L+K 
Sbjct: 3384 HLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFCDQ----------------QLRKE 3427

Query: 1746 DVSASLPPSSE---YPVLVVRYIMKAIQMDINLQIQHGIARVLTLLGHY-SNTHSEFVHQ 1579
            + +AS+  S+E   YP LVV  ++KA++++ N + +    R+L ++  Y   T S    +
Sbjct: 3428 EENASVIDSAELQAYPALVVEKMLKALKLNSN-EARLKFPRLLQIIERYPEETLSLMTKE 3486

Query: 1578 QNGIPCWLFIAWIPQILAVLEKEEGAVLVSVLEDIAHLYPQALYFPYNASKSDF------ 1417
             + +PCW FI+WI  ++A+L+K++   +   +E+I   YPQA+ +P+  S   +      
Sbjct: 3487 ISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESYSFKDTS 3546

Query: 1416 -GPIGQERTSKISALLNNP-LLNGLVHALEDLTYPEQRLQYWLSHIRNCISVG--NTKDA 1249
             G   +E  ++I + L+   ++   ++AL+ L+ PE   + W + +R  ++    N K+ 
Sbjct: 3547 TGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTPVNKKNI 3606

Query: 1248 EATFHQMFEDCLDSEAMSSRKSGTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESI 1069
            E  + +M+    D +A      G +  KF + + K+  K  G  GSKL  M    +    
Sbjct: 3607 EKMYERMYAALGDPKAPGL---GAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDF---- 3659

Query: 1068 KDLAENLAKSQRNLQTGKISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXXXXXXXXXXX 889
             D+   L            +L   S WM+++     F+R                     
Sbjct: 3660 NDITNMLLLKMNKDSKPPGNLKECSPWMSDFKVE--FLRN------------------EL 3699

Query: 888  XIPGHYTGFKKPDPSSHVKLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLR 709
             IPG Y G  KP P  HV++  FD+ +T ++S +RPK + +RG DE+++ FLVKGGEDLR
Sbjct: 3700 EIPGQYDGRGKPLPEYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLR 3759

Query: 708  LDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDG 529
             DQR+EQLF VMN IL++D  CS++ L LRTY+VVP++ + G+IE++E+T  + D++ + 
Sbjct: 3760 QDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNT 3819

Query: 528  LMHKMPSVRHATSKQEKNTPAGLLSSLRT---QYQDWILKKGGSSAKLSESYTNMYKKAS 358
            +           S++EK   A  LS  R    +Y+DW+ K  G       +Y  MYK A+
Sbjct: 3820 M-----------SQEEK---AAYLSDPRAPPCEYKDWLTKMSGKHD--VGAYMLMYKGAN 3863

Query: 357  AEDIKKEMEILTSQLPWDALKTGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDR 178
              +         S++P D LK    +++TS E+FLALRS F  S + + I  ++ G+GDR
Sbjct: 3864 RTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDR 3923

Query: 177  HLSNFLLDTKRGTLIPIDFGYSFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLL 7
            HL+NF++  + G +I IDFG++FG+    LPVPEL+PFRLT QF N++LP+   GL+
Sbjct: 3924 HLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLM 3980


>gb|EAW86683.1| protein kinase, DNA-activated, catalytic polypeptide, isoform CRA_d
            [Homo sapiens]
          Length = 4033

 Score =  375 bits (963), Expect = e-101
 Identities = 276/957 (28%), Positives = 473/957 (49%), Gaps = 46/957 (4%)
 Frame = -1

Query: 2739 ELASLAVVTDQFDLAVFYLKKFYESFRMKWSSVHPLATASKHILLKKLQQVVELDEYVEH 2560
            EL+ L ++ D  D A +Y++   +SF   +SS+  L   S+   L+ +Q + E+ E++  
Sbjct: 2990 ELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVLLHQSRLTKLQSVQALTEIQEFISF 3049

Query: 2559 ITKERNEAS---LTRLFNVWHKRWPSPQFDDVEAWDDVLQNRLLYFEKTQQLV------G 2407
            I+K+ N +S   L RL N W  R+P  + D +  WDD++ NR  +  K ++ +       
Sbjct: 3050 ISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWDDIITNRCFFLSKIEEKLTPLPEDN 3109

Query: 2406 RQLLKEDGDFDKQRVVDLDFEKANIFYEAARGLILQGSYDAS--QGYMNQYMAAIEGSNK 2233
               + +DGD   +  V    E  +    + +  +     D++  Q   +  M  ++  +K
Sbjct: 3110 SMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKMKMIDSARKQNNFSLAMKLLKELHK 3169

Query: 2232 KEKLNFDFFNTLVKLRCL--------QADRESTIDAFEAVTMLQQ--VRDYVTSTARKAL 2083
            + K   D+  + V+  C         Q   E  +   + V++L +  V  Y++       
Sbjct: 3170 ESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTVLKTVSLLDENNVSSYLSKNILAFR 3229

Query: 2082 YQN---QTKWRAGLKMLEGDVT--SKLATFSLKSLSENSVSPKEIENCVSLFGSAYAAYS 1918
             QN    T +R     L  +    +++     + + E S S  E    V + G    A+ 
Sbjct: 3230 DQNILLGTTYRIIANALSSEPACLAEIEEDKARRILELSGSSSEDSEKV-IAGLYQRAFQ 3288

Query: 1917 KLFSEVSSADPFVHDEFFT---SRKIAKAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKG 1747
             L   V +A+       ++   +  +  AY+  A FCD+                +L+K 
Sbjct: 3289 HLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFCDQ----------------QLRKE 3332

Query: 1746 DVSASLPPSSE---YPVLVVRYIMKAIQMDINLQIQHGIARVLTLLGHY-SNTHSEFVHQ 1579
            + +AS+  S+E   YP LVV  ++KA++++ N + +    R+L ++  Y   T S    +
Sbjct: 3333 EENASVIDSAELQAYPALVVEKMLKALKLNSN-EARLKFPRLLQIIERYPEETLSLMTKE 3391

Query: 1578 QNGIPCWLFIAWIPQILAVLEKEEGAVLVSVLEDIAHLYPQALYFPYNASKSDF------ 1417
             + +PCW FI+WI  ++A+L+K++   +   +E+I   YPQA+ +P+  S   +      
Sbjct: 3392 ISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESYSFKDTS 3451

Query: 1416 -GPIGQERTSKISALLNNP-LLNGLVHALEDLTYPEQRLQYWLSHIRNCISVG--NTKDA 1249
             G   +E  ++I + L+   ++   ++AL+ L+ PE   + W + +R  ++    N K+ 
Sbjct: 3452 TGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTPVNKKNI 3511

Query: 1248 EATFHQMFEDCLDSEAMSSRKSGTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESI 1069
            E  + +M+    D +A      G +  KF + + K+  K  G  GSKL  M    +    
Sbjct: 3512 EKMYERMYAALGDPKAPGL---GAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDF---- 3564

Query: 1068 KDLAENLAKSQRNLQTGKISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXXXXXXXXXXX 889
             D+   L            +L   S WM+++     F+R                     
Sbjct: 3565 NDITNMLLLKMNKDSKPPGNLKECSPWMSDFKVE--FLRN------------------EL 3604

Query: 888  XIPGHYTGFKKPDPSSHVKLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLR 709
             IPG Y G  KP P  HV++  FD+ +T ++S +RPK + +RG DE+++ FLVKGGEDLR
Sbjct: 3605 EIPGQYDGRGKPLPEYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLR 3664

Query: 708  LDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDG 529
             DQR+EQLF VMN IL++D  CS++ L LRTY+VVP++ + G+IE++E+T  + D++ + 
Sbjct: 3665 QDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNT 3724

Query: 528  LMHKMPSVRHATSKQEKNTPAGLLSSLRT---QYQDWILKKGGSSAKLSESYTNMYKKAS 358
            +           S++EK   A  LS  R    +Y+DW+ K  G       +Y  MYK A+
Sbjct: 3725 M-----------SQEEK---AAYLSDPRAPPCEYKDWLTKMSGKHD--VGAYMLMYKGAN 3768

Query: 357  AEDIKKEMEILTSQLPWDALKTGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDR 178
              +         S++P D LK    +++TS E+FLALRS F  S + + I  ++ G+GDR
Sbjct: 3769 RTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDR 3828

Query: 177  HLSNFLLDTKRGTLIPIDFGYSFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLL 7
            HL+NF++  + G +I IDFG++FG+    LPVPEL+PFRLT QF N++LP+   GL+
Sbjct: 3829 HLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLM 3885


>ref|XP_006221286.1| PREDICTED: DNA-dependent protein kinase catalytic subunit isoform X2
            [Rattus norvegicus] gi|564377846|ref|XP_006248794.1|
            PREDICTED: DNA-dependent protein kinase catalytic subunit
            isoform X2 [Rattus norvegicus]
          Length = 4059

 Score =  374 bits (961), Expect = e-101
 Identities = 271/952 (28%), Positives = 465/952 (48%), Gaps = 41/952 (4%)
 Frame = -1

Query: 2739 ELASLAVVTDQFDLAVFYLKKFYESFRMKWSSVHPLATASKHILLKKLQQVVELDEYVEH 2560
            EL+ L ++ D  D A +Y+K   + F   +SS+  L   S+   L+ +Q + E++E++  
Sbjct: 3017 ELSLLYILQDDIDRATYYIKNAIQIFMQNYSSIDVLLYRSRLAKLQSVQTLAEIEEFLNF 3076

Query: 2559 ITKERNEASL---TRLFNVWHKRWPSPQFDDVEAWDDVLQNRLLYFEKTQQLV----GRQ 2401
            I K  + +SL    RL   W  R+P    D +  WDD++ NR  +  K ++ +    G  
Sbjct: 3077 IRKHGDLSSLGPLRRLLKTWTSRYPDTVTDPMHIWDDIITNRCFFLSKIEERLTVSPGDH 3136

Query: 2400 LLKEDGDFDK-QRVVDLDFEKANIFYEAARGLILQGSYDAS--QGYMNQYMAAIEGSNKK 2230
             +  D D D   R      E A+   ++ R  +     ++S  Q   +  M  ++  +K+
Sbjct: 3137 SMSVDEDEDSFAREGSEPKEDAHHILQSCRFTMKMKMIESSWKQNNFSLSMKLLKEMHKE 3196

Query: 2229 EKLNFDFFNTLVKLRC--------LQADRESTIDAFEAVTMLQQ--VRDYVTSTARKALY 2080
             K+   +    +   C         Q+ +E  +   + +T+L +  + +Y+    +    
Sbjct: 3197 SKIRESWRMQWIHSFCQLNHCRSHTQSPQEQVLTMLKTITLLDESDISNYLNKNIQAFCD 3256

Query: 2079 QN---QTKWRAGLKMLEGDVTSKLATFSLKSLSENSVSPKEIENCVSLFGSAYA-AYSKL 1912
            QN    T  R     L  +          K+ S  ++S    EN   +    Y  A+  L
Sbjct: 3257 QNILLGTSCRIMADALSREPACLSGLEKSKTESIFALSGSNTENTERVISGLYQRAFHHL 3316

Query: 1911 FSEVSSADPFVHDEFF---TSRKIAKAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKGDV 1741
               V SA+       +    + + A AY+    FCD+ L              K+++   
Sbjct: 3317 SMAVQSAEEETQLSCWGHEAAAERAHAYMTLVGFCDQQLR-------------KVEESAS 3363

Query: 1740 SASLPPSSE---YPVLVVRYIMKAIQMDINLQIQHGIARVLTLLGHY-SNTHSEFVHQQN 1573
            +AS   S+E   YP LVV  +++A++++ + + +    R+L ++  Y   T +  + + +
Sbjct: 3364 TASQKISTELEGYPALVVEKMLRALKLNSS-EARLKFPRLLQIIEQYPEETVNIIIKEIS 3422

Query: 1572 GIPCWLFIAWIPQILAVLEKEEGAVLVSVLEDIAHLYPQALYFPYNASKSDF-------G 1414
             IPCW FI WI  ++A+L+KEE   +   +E+IA  YPQA+ +P+  S   +       G
Sbjct: 3423 SIPCWQFIGWIGHMVALLDKEEAIAVQHTVEEIADNYPQAIIYPFIISSESYSFQNTSSG 3482

Query: 1413 PIGQERTSKISALLNNP-LLNGLVHALEDLTYPEQRLQYWLSHIRNCISVG--NTKDAEA 1243
               +    +I + L+   ++ G ++AL+ L+ P+   + W++  ++ +     N K+ E 
Sbjct: 3483 HNNKAFVERIKSKLDQGGVIQGFINALDQLSNPDMLFKDWVNDTKDELGKNPVNKKNIEK 3542

Query: 1242 TFHQMFEDCLDSEAMSSRKSGTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESIKD 1063
             + +M+    D  A      G +  KF + + K+ +K+ G  GSKL +M      +  ++
Sbjct: 3543 LYERMYAALGDFRAPGL---GPFRRKFIQTFGKEFVKSFGNGGSKLLTMK----LDEFRN 3595

Query: 1062 LAENLAKSQRNLQTGKISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXXXXXXXXXXXXI 883
            + ++L    R       +L   S WM+E+                              I
Sbjct: 3596 ITDSLFVRMRKDSKLPGNLKEYSPWMSEFTVKSEL-----------------------EI 3632

Query: 882  PGHYTGFKKPDPSSHVKLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLRLD 703
            PG Y G  KP P  HV++  FD+ +  + S ++PK + +RG DEK+Y FLVKGGEDLR D
Sbjct: 3633 PGQYDGKSKPLPEYHVRISGFDERVKVMVSLRKPKRIVIRGHDEKEYPFLVKGGEDLRQD 3692

Query: 702  QRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDGLM 523
            QRIEQLF VMN ILS+D  CS++ + LRTY VVP++ + G+IE+IE+T  + D++   + 
Sbjct: 3693 QRIEQLFEVMNAILSQDAACSQRNMQLRTYRVVPMTSRLGLIEWIENTMTLKDLLLSNM- 3751

Query: 522  HKMPSVRHATSKQEKNTPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAEDIK 343
                      S++EK        +    Y+DW++K  G S    + YT MY +A+  +  
Sbjct: 3752 ----------SQEEKVAYDSDSKAPIYDYRDWLIKVSGRSD--VKGYTLMYSRANRTETV 3799

Query: 342  KEMEILTSQLPWDALKTGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLSNF 163
                   +++P D LK    K++TS E+FLALRS F  S + L I  ++ G+GDRHL+NF
Sbjct: 3800 TAFRRRENKVPADLLKRAFVKMSTSPEAFLALRSHFASSHALLCISHWLLGIGDRHLNNF 3859

Query: 162  LLDTKRGTLIPIDFGYSFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLL 7
            ++  + G++I IDFG++FG+    LP+PEL+PFRLT QF +++LP+   GL+
Sbjct: 3860 MVAMETGSVIGIDFGHAFGSATQFLPIPELMPFRLTRQFISLMLPMKETGLV 3911