BLASTX nr result
ID: Ephedra28_contig00005390
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Ephedra28_contig00005390
(3824 letters)
Database: ./nr
37,332,560 sequences; 13,225,080,153 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|XP_001323102.1| viral A-type inclusion protein [Trichomonas ... 150 5e-33
ref|XP_001318285.1| viral A-type inclusion protein [Trichomonas ... 148 2e-32
ref|XP_005159740.1| PREDICTED: titin isoform X3 [Danio rerio] 145 2e-31
ref|XP_001579764.1| viral A-type inclusion protein [Trichomonas ... 144 2e-31
ref|XP_001304086.1| hypothetical protein [Trichomonas vaginalis ... 140 4e-30
ref|XP_001014708.1| DNA-directed RNA polymerase, omega subunit f... 138 2e-29
ref|XP_005159741.1| PREDICTED: titin isoform X4 [Danio rerio] 136 6e-29
ref|XP_005159739.1| PREDICTED: titin isoform X2 [Danio rerio] 136 6e-29
ref|XP_005159738.1| PREDICTED: titin isoform X1 [Danio rerio] 136 6e-29
ref|XP_685984.6| PREDICTED: titin isoform X7 [Danio rerio] 136 6e-29
ref|XP_001312904.1| viral A-type inclusion protein [Trichomonas ... 135 1e-28
ref|XP_653447.1| Viral A-type inclusion protein repeat [Entamoeb... 134 2e-28
ref|XP_001581403.1| viral A-type inclusion protein [Trichomonas ... 134 2e-28
ref|XP_001330650.1| viral A-type inclusion protein [Trichomonas ... 134 3e-28
ref|XP_006789762.1| PREDICTED: CAP-Gly domain-containing linker ... 131 2e-27
ref|XP_006789761.1| PREDICTED: CAP-Gly domain-containing linker ... 131 2e-27
ref|XP_006789759.1| PREDICTED: CAP-Gly domain-containing linker ... 131 2e-27
ref|XP_001323236.1| viral A-type inclusion protein [Trichomonas ... 131 3e-27
ref|XP_006789763.1| PREDICTED: CAP-Gly domain-containing linker ... 130 3e-27
ref|XP_001582404.1| viral A-type inclusion protein [Trichomonas ... 129 8e-27
>ref|XP_001323102.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121905960|gb|EAY10879.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 4057
Score = 150 bits (378), Expect = 5e-33
Identities = 256/1224 (20%), Positives = 509/1224 (41%), Gaps = 71/1224 (5%)
Frame = +2
Query: 362 DTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGLYVSNVVSDAVLNGVVSAQE 541
DT L+ NFDL Q+N V L D+ TK L ++++ N + E
Sbjct: 1345 DTKQKLQKQNFDL-QNN--VSNLTNDLEKTKRELLSLQNSK-----------NDNIKQLE 1390
Query: 542 EEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFI 721
+E + L K++EN + +KI++L +I +L+ T+ K+ I ++ + + + L DFI
Sbjct: 1391 QEKELILKQKENENKISEEKIKNLTLQISNLQNTISQKDNEIQNNLQNLQKVSNEL-DFI 1449
Query: 722 ------HEKDLMQQ-------------RAQETEQKLASRDNEMMHMVLEKDNIILSLHKQ 844
HE DL ++ + +E E+K E + EKD +I L +
Sbjct: 1450 KNSTKDHENDLTEKEDVINNLRKLFDDKMKENEKKT----KEFQDSLREKDLMISQLENK 1505
Query: 845 IELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQD 1024
Q +S D + D ++ QN+ + E + ++ + ++++ E L+ E+ +Q
Sbjct: 1506 TMFFDQQMKSKDD-KIDSLQIQNVTFQGELKEIQNKLINSLKQIDE----LQKENESFQK 1560
Query: 1025 EIQSLK---DECHAKEMSKQAEISKLSHTLEESIMN-SNLESLFTAEIYENTFRELGDQI 1192
E+Q+ D+ H + QA+I + ++ N +NL++ YEN + ++I
Sbjct: 1561 ELQTRDQNLDDSHKQIEELQAKIDQYEEEIKSKDENLNNLQNKINN--YENESKTNNEKI 1618
Query: 1193 SQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQC 1372
++ S I+ L + + +E +L+ + ++ + Q
Sbjct: 1619 KEMEGKQKSNELQINDLQNNVSQTENENKQLKSELEKLQTEIKSKSDQLNEIQNESKSQS 1678
Query: 1373 SKL---KDELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXX 1543
++ + EL+E + K++ +L++I +LQK N + ++++
Sbjct: 1679 EQIVTFQGELKELQNKLTSSLKQIDELQKENESFQKELQTRDQ----------------- 1721
Query: 1544 XXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQ 1723
L++ QI + ID+ E E+ + +++LQ ++N + E + +
Sbjct: 1722 ------------NLDDSHKQIEELQAKIDQYEEEIKSKDENLNNLQNKINNYENESKTNN 1769
Query: 1724 KVLQSFESHI---EKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQV 1894
+ ++ E E +ND + V + +N + L++ ++ +Q ++
Sbjct: 1770 EKIKEMEGKQKSNELQINDLQNNVS---------------QTENENKQLKSELEKLQTEI 1814
Query: 1895 AVSQEQ--HIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLN 2068
+Q I+++ K + E + F +++ S K+E + +E E LN
Sbjct: 1815 KSKSDQLNEIQNESKSQSEQIVT------FQDEVKS----KDEKLQTQEEQIKELENKLN 1864
Query: 2069 ELK-SLHQDLEL-LKAEEAVKSLSNNVGVSTKGIHYFS--QLIQEGKDGEASDVQGKSRA 2236
EL+ SL +L ++ + K L+N V+ + Q+ +E D + S+ +
Sbjct: 1865 ELENSLRNKGDLQVQLNDREKELNNLKKVNENLVKQVEDLQVNKEQSDKKLSENDEELTN 1924
Query: 2237 LRRHST-----GQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPL 2401
LRR++ + RE + + + ++ E + +L + + S
Sbjct: 1925 LRRNNADLKKQNEKLRENKEKNESEIISLQNRLSELTNSHNDELFTVKRKLEENNSIVKQ 1984
Query: 2402 RNWPKEQLLGHFKQSFAGLKREYELELQR---KTEEIYDLKRLLLNEKNGLHAXXXXXXX 2572
+N E L KQ + E +LQ+ ++E + L L E N L
Sbjct: 1985 QNAKIEML----KQQLIDQNKTIE-DLQKIINESENLQFLVSTLKTENNTLKKVTQDNDL 2039
Query: 2573 XXXXXVAEITGKFEKVLQENKLLPVE---EVQRYKMLCVLKEELQSKIDSLLKE---IKE 2734
++ + + +NKL E ++Q+ K L E +QSK++ +K+ + +
Sbjct: 2040 QNKKTNEDLLSQINDL--QNKLKETEKSSQIQKSKYESQLNE-IQSKLNQSIKDNSDLMD 2096
Query: 2735 KDSNS-KVLAEKLSDALKKSADHAQR---ESHLLKHIADLEAGITDR--EIMTSVCSD-- 2890
K N K L EKL ++ K+ D ++ S LL L D+ E +T+V S+
Sbjct: 2097 KHENELKNLDEKLQESQKQKNDLEKKFEMNSKLLNENNKLRQEKFDKTLEELTNVKSENG 2156
Query: 2891 VLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDK-DKLLCLVGEENKEHKRQI 3067
L ++ +EK L Q N+ +L+K L D+L + N ++
Sbjct: 2157 KLKEQIDDLEKEKNEMTILLNTTQNNQNEDLQNLQKKLNATIDELKMTTNDYNSLKEK-- 2214
Query: 3068 AILEKLKEETENNPGRVFLQSEEREKI-------EEQKRVLDQALQECEELKNDIQNKHS 3226
EKL +++N+ + E +K+ +E+ + L L E E+ + +Q +
Sbjct: 2215 --FEKLNGKSDNDNSLISSLKRENDKMKNDLQKTQEENKSLVLKLNENEKTISKLQKTND 2272
Query: 3227 DIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKN 3406
+I E N +L+ + SNL +L N N+ L++
Sbjct: 2273 EISRKLTFVETENGELKLTVNEMDEKVTTNETNSNEKERLISNLQKQNKQLENENKTLQS 2332
Query: 3407 EIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATRE 3586
EI+ TD + + K++LN+ EQK + L ++ + + ++ + S ++
Sbjct: 2333 EIKSLQTDEFVKDQMKKQLND--------YEQKVSKLEDEKRQLQNEMTKYKDDNSTMKK 2384
Query: 3587 QTEKYRDLLNSLTEEHADL--KKQFLSAT--EELQSKERDLEVAMTETKFLKEKLLVSDE 3754
K ++ L + DL KQ + T EEL S E + E E K LKE+ L ++
Sbjct: 2385 VLTKQEKIIQKLNTKVEDLTETKQTMKQTQSEELSSLEEENEQKKEELKHLKEEFLEKEK 2444
Query: 3755 NLK--EKDLQLRAFEIANSEKQYQ 3820
LK EK +Q +I + +++ +
Sbjct: 2445 RLKGLEKSIQKVTEKITSQKEEIE 2468
Score = 122 bits (305), Expect = 2e-24
Identities = 241/1199 (20%), Positives = 495/1199 (41%), Gaps = 42/1199 (3%)
Frame = +2
Query: 296 DTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGL-------LEDIRNTK 454
+T+++++ +E L +E LK++ + + + GL E I + K
Sbjct: 2405 ETKQTMKQTQSEELSSLEEENEQKKEELKHLKEEFLEKEKRLKGLEKSIQKVTEKITSQK 2464
Query: 455 DLLDTV-ESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWS 631
+ ++ + + L N +S+ L +S E+E + + ++ ++ + + + S
Sbjct: 2465 EEIENLRKQKLIDDNTISE--LKSSISENEKELENLRKSDSDKSDIIEQLKSESENLSMS 2522
Query: 632 LEETLQYKEEV------ILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEM 793
L+ Y+ E+ I ++ IS+++ LK + +Q++ QETE+K +
Sbjct: 2523 LKSRSNYENELTKLQNKIQKLNDQISDKEDDLKSKEILLEKLQKKVQETEEKFSETQKLN 2582
Query: 794 MHMVLEKDNIILSLHK-QIELQSQNTQSLDCFRRDEIEDQNIKEEIE-KQIVETIYVTQI 967
M E NI L Q+EL S+ T+ ++ +D + N+KE++ + ++ +
Sbjct: 2583 KTMKDENANISNQLRALQMELNSK-TKQIEKLVKD---NTNLKEKVTILEFKQSNFDDDN 2638
Query: 968 QELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSK-QAEISKLSHTLEESIMN-SNLESL 1141
+E +E + LE+ + + Q + +E + K++ + + +IS+L++ +E + N +L
Sbjct: 2639 KE--KEEKIENLENDNFNLKKQIILNEEYKKQIDELKFQISQLNYDNKEKVTRLQNENTL 2696
Query: 1142 FTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXX 1321
+ +N +++ ++ + S I+ L + D E L++Q
Sbjct: 2697 LKTKSLQNK-----SELNTVKKEREDLQSEIEELKMKFDLEQKENENLKKQ----NKEIK 2747
Query: 1322 XXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSIXX 1501
+ K +E S K EL + + +N + S+L+K E+ S S+N +
Sbjct: 2748 NQFETTKSEKIYLEKDISNAKTELND---LLDKNNKLESELRKKEREITRLSYSENKLND 2804
Query: 1502 XXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQ 1681
+L +L ++ S I++ E+S + I S
Sbjct: 2805 LQI-----------------------ELNKLKSEMKDKTSEIERLSNELSLKSEEIYSFS 2841
Query: 1682 TVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETL 1861
++ + EI+ ++S E+ I+K+ ++ I ++N
Sbjct: 2842 CSSNSFEKEIQTKSDKIKSLENEIKKVQKEN----------------EQIKDLENQLNEK 2885
Query: 1862 RAFVKNIQNQVAVSQEQH--IEHQCKEELEGHIADL-VLNDFSNDILSWSRRKEEAVVHD 2032
++N+Q + E+H + + ++++G DL VL+D + +++ EE +
Sbjct: 2886 SLIIENLQKEFKQKDEKHETVLNSMNDKMKGLQNDLSVLSDLQRENEKITKQNEEIKSQN 2945
Query: 2033 DEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEAS 2212
+ E E+K L L+ K + + +L + + + I + ++++ K +
Sbjct: 2946 KKLKEENDDKNREIKKLSNTLQ--KGDIEMNTLKDLLQTKEEKIRNYEDILEKTK----T 2999
Query: 2213 DVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASD 2392
++ K+ + Q K L + + T + K + +
Sbjct: 3000 QMEDKNYEFSKTVKDQ----NDKINQLEKELEQRDLELDDLTNKSKSFDDEKNDKIQSLT 3055
Query: 2393 SPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXX 2572
+ +N KE ++ G+ + E I +L+ L + + L
Sbjct: 3056 TENKNLKKE------NRTLKGIINSVKKSSNELEERIRNLESQLKSHSSSLIELQEKKET 3109
Query: 2573 XXXXXVAEITGKFEKVLQENKLLP--VEEVQRYKMLCVLKEELQSKIDS-LLKEIKEKDS 2743
EI + EK+ +N+ L +EV++ K EE+++K++S L +EI+
Sbjct: 3110 EISKLQKEIDEREEKIKSQNEKLSNCRKEVEKTKQEI---EEMKAKLNSQLTEEIQTIKG 3166
Query: 2744 NSKVLAEKLSDALKKSADHAQRESHLLKHIAD-----LEAGITDREIMTSVCSDVLTALF 2908
+ L EK+ ++ K D ++ LK D L++ I +RE + +D LT
Sbjct: 3167 EKEDLLEKIK-SINKERDELSQQIKSLKRENDDLQQKLKSVIEEREKLEKEVND-LTQQI 3224
Query: 2909 VEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLK 3088
+ E E + KE E ++K L+ E+K KL +N + +++ LE +K
Sbjct: 3225 KSLKNEIEEQKEKSKKEIENFSEK---LKSSNEEKQKL----QNQNDDLQQK---LESIK 3274
Query: 3089 EETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNK 3268
EE EN +RE K++ Q+ +E ++L +I S IDSL E +KLN
Sbjct: 3275 EEREN---------LKRENDLINKKLKSQS-EELQKLNKEIDYSKSQIDSLDEVNKKLNS 3324
Query: 3269 QLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIK 3448
+ L+ +L +L NEI+K +++ + LI
Sbjct: 3325 ---------------------TNEQENKQLNDQINKLTTKVNDLNNEIKKLTSEKNDLID 3363
Query: 3449 EKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKI-------LLLESSQSATREQTEKYR- 3604
+ + LNE L+ +++ L E+L +++I L+S + +++ K
Sbjct: 3364 QNKRLNEDLSKKVNQFDEETQKLNEQLKRSKEEINDINNQNKKLDSLNNDLKQENNKLNH 3423
Query: 3605 --DLLNSLTEEHADLKKQFLSATEE---LQSKERDLEVAMTETKFLKEKLLVSDENLKE 3766
LNSLT E + KK+F S EE L S +L+ E + + +KL +E +KE
Sbjct: 3424 EITKLNSLTNEFNEQKKKFDSVKEENLRLNSLNNELK---QENEEISKKLKSLNEQIKE 3479
Score = 121 bits (304), Expect = 2e-24
Identities = 248/1325 (18%), Positives = 538/1325 (40%), Gaps = 153/1325 (11%)
Frame = +2
Query: 305 KSLETKIAETLERMEIHEGDTANTLKNMNFDLG---QDNPGVPGLLEDIRNTKDLLDTV- 472
K LE K+ E LE ++GD L + +L + N + +ED++ K+ D
Sbjct: 1857 KELENKLNE-LENSLRNKGDLQVQLNDREKELNNLKKVNENLVKQVEDLQVNKEQSDKKL 1915
Query: 473 -ESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDL----NHKIWSLE 637
E+ ++N+ + N + Q E+ +E +SE L ++ +L N ++++++
Sbjct: 1916 SENDEELTNLRRN---NADLKKQNEKLRENKEKNESEIISLQNRLSELTNSHNDELFTVK 1972
Query: 638 ETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLE-- 811
L+ ++ + I + L D Q + E QK+ + + +V
Sbjct: 1973 RKLEENNSIVKQQNAKIEMLKQQLID--------QNKTIEDLQKIINESENLQFLVSTLK 2024
Query: 812 -KDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEH 988
++N + + + +LQ++ T + ++++++ + E QI ++ Y +Q+ E+ +
Sbjct: 2025 TENNTLKKVTQDNDLQNKKTNEDLLSQINDLQNKLKETEKSSQIQKSKYESQLNEIQSKL 2084
Query: 989 DLLRLESA----KYQDEIQSLKDECHAKEMSKQ---------AEISKLSHTLEESIMNSN 1129
+ +++ K+++E+++L ++ + K +++ ++ L + +
Sbjct: 2085 NQSIKDNSDLMDKHENELKNLDEKLQESQKQKNDLEKKFEMNSKLLNENNKLRQEKFDKT 2144
Query: 1130 LESLFTAEIYENTFRELGDQISQLRNDMY--------SKNSYIDSLASRID-------FL 1264
LE L + +E D + + +N+M ++N + +L +++
Sbjct: 2145 LEELTNVKSENGKLKEQIDDLEKEKNEMTILLNTTQNNQNEDLQNLQKKLNATIDELKMT 2204
Query: 1265 SSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERG---KISENLERI 1435
+++ N L+E+ +LK + + L+ EE + K++EN + I
Sbjct: 2205 TNDYNSLKEKFEKLNGKSDNDNSLISSLKRENDKMKNDLQKTQEENKSLVLKLNENEKTI 2264
Query: 1436 SKLQKMNNELA--------ERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKL-- 1585
SKLQK N+E++ E + + ++ + N+ +K
Sbjct: 2265 SKLQKTNDEISRKLTFVETENGELKLTVNEMDEKVTTNETNSNEKERLISNLQKQNKQLE 2324
Query: 1586 --------------------EELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKF 1705
+++ Q+N + + K E E + ++ + S K
Sbjct: 2325 NENKTLQSEIKSLQTDEFVKDQMKKQLNDYEQKVSKLEDEKRQLQNEMTKYKDDNSTMKK 2384
Query: 1706 EIEKSQKVLQSFESHIEKLV----------NDSLHEVDSAFCSLNSRFYSLIHKVDNSGE 1855
+ K +K++Q + +E L ++ L ++ L + +
Sbjct: 2385 VLTKQEKIIQKLNTKVEDLTETKQTMKQTQSEELSSLEEENEQKKEELKHLKEEFLEKEK 2444
Query: 1856 TLRAFVKNIQN--QVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVH 2029
L+ K+IQ + SQ++ IE+ K++L I D +++ + I E+ + +
Sbjct: 2445 RLKGLEKSIQKVTEKITSQKEEIENLRKQKL---IDDNTISELKSSI----SENEKELEN 2497
Query: 2030 DDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEA 2209
+ D+++ ++ +LKS ++L + ++KS SN TK + +L + D E
Sbjct: 2498 LRKSDSDKSDIIEQLKSESENLSM-----SLKSRSNYENELTKLQNKIQKLNDQISDKE- 2551
Query: 2210 SDVQGKSRALRR-----HSTGQAFREPPK-----PEDLYTTYSEGKIVEPHPTEEKKLLA 2359
D++ K L + T + F E K ++ ++ + ++ + K +
Sbjct: 2552 DDLKSKEILLEKLQKKVQETEEKFSETQKLNKTMKDENANISNQLRALQMELNSKTKQIE 2611
Query: 2360 ILAFETADASDSPLRNWPKEQLLGHFKQS-FAGLKREYELELQRKTEEIYDLKR-LLLNE 2533
L + N ++ + FKQS F +E E +++ + ++LK+ ++LNE
Sbjct: 2612 KLVKDNT--------NLKEKVTILEFKQSNFDDDNKEKEEKIENLENDNFNLKKQIILNE 2663
Query: 2534 --KNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLK---EELQ 2698
K + ++T ++ EN LL + +Q L +K E+LQ
Sbjct: 2664 EYKKQIDELKFQISQLNYDNKEKVT----RLQNENTLLKTKSLQNKSELNTVKKEREDLQ 2719
Query: 2699 SKIDSLL-----------------KEIK---EKDSNSKVLAEK-LSDALKKSADHAQRES 2815
S+I+ L KEIK E + K+ EK +S+A + D + +
Sbjct: 2720 SEIEELKMKFDLEQKENENLKKQNKEIKNQFETTKSEKIYLEKDISNAKTELNDLLDKNN 2779
Query: 2816 HLLKHIADLEAGITDREIMTSVCSDV---LTALFVEM------VREKEFSLSLATKEQET 2968
L + E IT + +D+ L L EM + LSL ++E +
Sbjct: 2780 KLESELRKKEREITRLSYSENKLNDLQIELNKLKSEMKDKTSEIERLSNELSLKSEEIYS 2839
Query: 2969 VNQKQMSLRKMLEDK-DKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREK 3145
+ S K ++ K DK+ L E K K I + + E + LQ E ++K
Sbjct: 2840 FSCSSNSFEKEIQTKSDKIKSLENEIKKVQKENEQIKDLENQLNEKSLIIENLQKEFKQK 2899
Query: 3146 IEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXX 3325
E+ + VL+ + + L+ND+ S + L+ E EK+ KQ +
Sbjct: 2900 DEKHETVLNSMNDKMKGLQNDL----SVLSDLQRENEKITKQNEEIKSQNKKLKEENDDK 2955
Query: 3326 XXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQK 3505
+S+ L +E+ + L+ + EK D+L K K ++ ++ K ++ +
Sbjct: 2956 NREIKKLSNTLQKGDIEMNTLKDLLQTKEEKIRNYEDILEKTKTQMEDKNYEFSKTVKDQ 3015
Query: 3506 EAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQ----------F 3655
+ + E EQ+ L L+ + ++ ++ D + SLT E+ +LKK+
Sbjct: 3016 NDKINQLEKELEQRDLELDDLTNKSKSFDDEKNDKIQSLTTENKNLKKENRTLKGIINSV 3075
Query: 3656 LSATEELQSKERDLE----------VAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANS 3805
++ EL+ + R+LE + + E K + L + + +E+ ++ + +++N
Sbjct: 3076 KKSSNELEERIRNLESQLKSHSSSLIELQEKKETEISKLQKEIDEREEKIKSQNEKLSNC 3135
Query: 3806 EKQYQ 3820
K+ +
Sbjct: 3136 RKEVE 3140
Score = 119 bits (298), Expect = 1e-23
Identities = 260/1285 (20%), Positives = 532/1285 (41%), Gaps = 120/1285 (9%)
Frame = +2
Query: 296 DTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVE 475
D KSLE +I + + E +K++ L + + + L ++ + + +TV
Sbjct: 2856 DKIKSLENEIKKVQKENE--------QIKDLENQLNEKSLIIENLQKEFKQKDEKHETVL 2907
Query: 476 SGLYVS--------NVVSDAVL-NGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIW 628
+ + +V+SD N ++ Q EE K S+N L ++ +D N +I
Sbjct: 2908 NSMNDKMKGLQNDLSVLSDLQRENEKITKQNEEIK-------SQNKKLKEENDDKNREIK 2960
Query: 629 SLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVL 808
L TLQ + + + + + ++ ++++ +D++++ T+ ++ ++ E V
Sbjct: 2961 KLSNTLQKGDIEMNTLKDLLQTKEEKIRNY---EDILEK----TKTQMEDKNYEFSKTVK 3013
Query: 809 EKDNIILSLHKQIELQ-------SQNTQSLDCFRRDEI-----EDQNIKEE--------- 925
++++ I L K++E + + ++S D + D+I E++N+K+E
Sbjct: 3014 DQNDKINQLEKELEQRDLELDDLTNKSKSFDDEKNDKIQSLTTENKNLKKENRTLKGIIN 3073
Query: 926 ----IEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKL 1093
++ E I + Q L+ L+ K + EI L+ E +E +++ KL
Sbjct: 3074 SVKKSSNELEERIRNLESQLKSHSSSLIELQEKK-ETEISKLQKEIDEREEKIKSQNEKL 3132
Query: 1094 SHTLEE--------SIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLAS 1249
S+ +E M + L S T EI + + + L + S N D L+
Sbjct: 3133 SNCRKEVEKTKQEIEEMKAKLNSQLTEEI-----QTIKGEKEDLLEKIKSINKERDELSQ 3187
Query: 1250 RIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLE 1429
+I L E + LQ++ L Q LK+E+EE++ K + +E
Sbjct: 3188 QIKSLKRENDDLQQKLKSVIEEREKLEKEVNDLT----QQIKSLKNEIEEQKEKSKKEIE 3243
Query: 1430 RISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEE---LTD 1600
S+ K +NE ++ ++QN ++N S+ EE L
Sbjct: 3244 NFSEKLKSSNEEKQKLQNQNDDLQQKLESIKEERENLKRENDLINKKLKSQSEELQKLNK 3303
Query: 1601 QINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLH 1780
+I+ S ID + EV+ L++ + + N +I K + + I+KL ++
Sbjct: 3304 EIDYSKSQIDSLD-EVNKKLNSTNEQENKQLND--QINKLTTKVNDLNNEIKKLTSEKND 3360
Query: 1781 EVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQH-----IEHQCKEE-- 1939
+D LN +++ D + L +K + ++ Q+ + + K+E
Sbjct: 3361 LIDQN-KRLNEDLSKKVNQFDEETQKLNEQLKRSKEEINDINNQNKKLDSLNNDLKQENN 3419
Query: 1940 -LEGHIADL--VLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDL--ELL 2104
L I L + N+F+ + KEE + +L NELK ++++ +L
Sbjct: 3420 KLNHEITKLNSLTNEFNEQKKKFDSVKEE--------NLRLNSLNNELKQENEEISKKLK 3471
Query: 2105 KAEEAVKSLSN-----NVGVSTKGIH---YFSQLIQEGKDGEASDVQGKSRALRRHSTGQ 2260
E +K ++N + + K ++ F++ + + K+ A +Q + ++ +
Sbjct: 3472 SLNEQIKEITNENNQDQIDLLNKKLNENETFTRKLNDDKENLAKKLQISNEENKKLN--- 3528
Query: 2261 AFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFK 2440
K EDL E K EE L+ + + + + L+ K+Q K
Sbjct: 3529 -----KKVEDLSEELEESK-----QREENSLIDL---QNKNETLENLKTQIKKQ-----K 3570
Query: 2441 QSFAGLKRE---YELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKF 2611
Q + RE + EL+ EI D + + N+K + ++T
Sbjct: 3571 QQIQEINRENNNLKQELENSQIEIDDFQNQIENQK------------LKIDNLQKVTINN 3618
Query: 2612 EKVLQE--NKLLPVEEVQRYKMLCV-----LKEELQSKIDSLLKEIKEKDSNSKVLAEKL 2770
EK+++E N+ L ++ + L + KE+++ + D L+++++ S+ L + L
Sbjct: 3619 EKIIKELKNENLELKSLTSDLQLSLHSSQSEKEKIEKQNDENLRDLQKAKSDISDLTKLL 3678
Query: 2771 -SDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVE----------- 2914
+++ + S D+ ++ + D+ A +M S+ + L E
Sbjct: 3679 KNNSPQASIDNRRKFQISQTNTTDIAAVSGTFSVMEDPISEEIEQLKDENNKMKKDLSQK 3738
Query: 2915 ---MVREKEFSLSLATKEQETVNQKQ-------MSLRKMLEDKDKLLCLVG----EENKE 3052
+ ++ EF L ++ ++T ++K+ +S+ ++ D D L + +EN E
Sbjct: 3739 IRNLQKDNEF---LKSELEKTKSEKENGLLGTKLSISEISNDNDVYLMKINNDLVKENSE 3795
Query: 3053 HKRQIAILEK-------LKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDI 3211
K +I++LEK + +E ++ + + + R+++EE+ + L ++ +E L I
Sbjct: 3796 LKIRISLLEKENEEMKQINKEKKDRTSEMLREKDMRKRMEEELQKLRRSDKEKNNLIQRI 3855
Query: 3212 QNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLE-LRNY 3388
+ K ++ +EE K+ +++ + I ++L E +
Sbjct: 3856 KRKE---ETAQEEVRKVKEEMIILKKVCDEKNAAFEKLSEEHKMILNSLKGRNNESILEE 3912
Query: 3389 NEELKNEIEKK-----STDIDLLIKEKEELNERLAY--TQKAMEQKEAVLVEKL--FEGE 3541
NE LK E+E S D L I E+ E N + A Q A ++ E L +KL E E
Sbjct: 3913 NERLKEELENARNESVSNDSYLKINEEVEKNLQTALESLQNAKDENER-LTKKLQKTERE 3971
Query: 3542 QKIL--LLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTE 3715
K L +++SS+ + E+ D L + ++ KK F + +++ K L +T
Sbjct: 3972 NKSLKQIIKSSEDLKSSEFEEEIDNLKTEVKKLRKEKKSFTNVASKMEKKIDKLTKTVTG 4031
Query: 3716 TKFLKEKLLVSDENLKEKDLQLRAF 3790
+ K S EN + ++RAF
Sbjct: 4032 VVEIVNKYSDSSENPTQ---EIRAF 4053
Score = 112 bits (279), Expect = 2e-21
Identities = 225/1225 (18%), Positives = 488/1225 (39%), Gaps = 59/1225 (4%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNT 451
IE+ R ++ +T+E + D N L N L Q ++I+N
Sbjct: 1193 IEMTKTNYPERSFNNDELHQTIEDNNVSMFDMQNKLNLANLKLKQSE-------KEIQNL 1245
Query: 452 KDLLDTVESGLYVSNVVSDAVLNGVVSAQEE--EFKEALAAKDSENFLLNKKIEDLNHKI 625
K+ L +++S N + + + S + E E +++ K+S+ + KK + K
Sbjct: 1246 KNELLSLQSENEEMNSTINMLKQSLTSKENEINELNDSVTVKNSQIEEILKKNQVKFDKT 1305
Query: 626 WSLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMV 805
+ E+ LQ + S++ I E+ + I ++ + + ++T+QKL ++ ++ + V
Sbjct: 1306 GNKEQQLQVLNSSLKHSNDIIQEKGKT----IDSQNKLIKNLEDTKQKLQKQNFDLQNNV 1361
Query: 806 LEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKE-EIEKQIVETIYVTQIQELGE 982
N + +++ L QN+++ + + ++ ++ +K+ E E +I E ++
Sbjct: 1362 SNLTNDLEKTKREL-LSLQNSKNDNIKQLEQEKELILKQKENENKISEEKIKNLTLQISN 1420
Query: 983 EHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYE 1162
+ + + + Q+ +Q+L+ + + K + + E+ + +NL LF ++ E
Sbjct: 1421 LQNTISQKDNEIQNNLQNLQKVSNELDFIKNSTKDHENDLTEKEDVINNLRKLFDDKMKE 1480
Query: 1163 NTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXX 1342
N + + ++ + K+ I L ++ F + ++
Sbjct: 1481 NE-----KKTKEFQDSLREKDLMISQLENKTMFFDQQMKSKDDKID-------------- 1521
Query: 1343 TLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXX 1522
S+++Q + EL+E + K+ +L++I +LQK N + ++++
Sbjct: 1522 ----SLQIQNVTFQGELKEIQNKLINSLKQIDELQKENESFQKELQTRDQ---------- 1567
Query: 1523 XXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQK 1702
L++ QI + ID+ E E+ + +++LQ ++N +
Sbjct: 1568 -------------------NLDDSHKQIEELQAKIDQYEEEIKSKDENLNNLQNKINNYE 1608
Query: 1703 FEIEKSQKVLQSFESHI---EKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFV 1873
E + + + ++ E E +ND + V + +N + L++ +
Sbjct: 1609 NESKTNNEKIKEMEGKQKSNELQINDLQNNVS---------------QTENENKQLKSEL 1653
Query: 1874 KNIQNQVAVSQEQ--HIEHQCKEELEGHIA-DLVLNDFSNDILSWSRRKEEAVVHDDEFD 2044
+ +Q ++ +Q I+++ K + E + L + N + S ++ +E ++ F
Sbjct: 1654 EKLQTEIKSKSDQLNEIQNESKSQSEQIVTFQGELKELQNKLTSSLKQIDELQKENESFQ 1713
Query: 2045 AERIALLNELKSLHQDLELLKA-----EEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEA 2209
E L H+ +E L+A EE +KS N+ I+ + + + +
Sbjct: 1714 KELQTRDQNLDDSHKQIEELQAKIDQYEEEIKSKDENLNNLQNKINNYENESKTNNE-KI 1772
Query: 2210 SDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADAS 2389
+++GK ++ + DL S+ E + K L L E S
Sbjct: 1773 KEMEGKQKS-----------NELQINDLQNNVSQ---TENENKQLKSELEKLQTEIKSKS 1818
Query: 2390 D--SPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLH--AXX 2557
D + ++N K Q +F + + +LQ + E+I +L+ L +N L
Sbjct: 1819 DQLNEIQNESKSQ--SEQIVTFQDEVKSKDEKLQTQEEQIKELENKLNELENSLRNKGDL 1876
Query: 2558 XXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQS---------KID 2710
+ + E ++++ + L V + Q K L EEL + K +
Sbjct: 1877 QVQLNDREKELNNLKKVNENLVKQVEDLQVNKEQSDKKLSENDEELTNLRRNNADLKKQN 1936
Query: 2711 SLLKEIKEKDSNSKV-LAEKLSDALKKSADHA-------QRESHLLKH----IADLEAGI 2854
L+E KEK+ + + L +LS+ D + + ++K I L+ +
Sbjct: 1937 EKLRENKEKNESEIISLQNRLSELTNSHNDELFTVKRKLEENNSIVKQQNAKIEMLKQQL 1996
Query: 2855 TDR----EIMTSVCSDVLTALF-VEMVREKEFSLSLATKEQETVNQKQMS--------LR 2995
D+ E + + ++ F V ++ + +L T++ + N+K L+
Sbjct: 1997 IDQNKTIEDLQKIINESENLQFLVSTLKTENNTLKKVTQDNDLQNKKTNEDLLSQINDLQ 2056
Query: 2996 KMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQ 3175
L++ +K + +++K + I KL + ++N S+ +K E + + LD+
Sbjct: 2057 NKLKETEKSSQI--QKSKYESQLNEIQSKLNQSIKDN-------SDLMDKHENELKNLDE 2107
Query: 3176 ALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSN 3355
LQE ++ KND++ K L E KL ++
Sbjct: 2108 KLQESQKQKNDLEKKFEMNSKLLNENNKLRQE---------------------------K 2140
Query: 3356 LDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFE 3535
D EL N +K+E K ID L KEK E+ L TQ + L +KL
Sbjct: 2141 FDKTLEELTN----VKSENGKLKEQIDDLEKEKNEMTILLNTTQNNQNEDLQNLQKKLNA 2196
Query: 3536 GEQKILLLESSQSATREQTEKY-------RDLLNSLTEEHADLKKQFLSATEELQSKERD 3694
++ + + ++ +E+ EK L++SL E+ +K ++ Q + +
Sbjct: 2197 TIDELKMTTNDYNSLKEKFEKLNGKSDNDNSLISSLKRENDKMKNDL----QKTQEENKS 2252
Query: 3695 LEVAMTETKFLKEKLLVSDENLKEK 3769
L + + E + KL +++ + K
Sbjct: 2253 LVLKLNENEKTISKLQKTNDEISRK 2277
Score = 89.4 bits (220), Expect = 1e-14
Identities = 227/1163 (19%), Positives = 470/1163 (40%), Gaps = 61/1163 (5%)
Frame = +2
Query: 518 NGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISER 697
N ++ ++ EE + EN L I+DLN+++ + ++ + L+ +
Sbjct: 527 NSLLKSENEELVSRVNQIKKENTQLKSDIQDLNNQLRNKKKDFAGSVQNQLNIIKLFL-- 584
Query: 698 DRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSL 877
++L DF +E Q+T+QK++ ++ + ++ + K +E Q + +
Sbjct: 585 NKLFADFNYE-------IQKTKQKISDEFLTILRKLQQQKENETNKTKLLERQINDLKQE 637
Query: 878 DCFRRDEIED-----QNIKEEIE---KQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQ 1033
+ +D+I D Q I +E E KQI + ++ + + +E D L K +++I+
Sbjct: 638 NMKLKDKINDLQNNLQKILQENENHSKQI--STHIDGLSQSIKERDDQIL---KDKEKIE 692
Query: 1034 SLKDECHAKEMSKQAEISKLSHTLEESI--MNSNLESLFTAEIYENTFRELGDQISQLRN 1207
+L+++ KE+ E S L E+ + + +E+L ++ +N + DQ+ + +
Sbjct: 693 NLQNKIKGKEIDFDQEKSNLIKQNEQKMKDLTDEMENL-KRKLLDNELDVVKDQLQKEKQ 751
Query: 1208 DMYSKNSYIDSLASRIDFLSSECNK-LQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLK 1384
I+ S I L + N+ L+E L+ + +K
Sbjct: 752 KSQDLEEKIEEKDSTIQILKEKINENLEESKKSYDKLMNDKQEEIALLQKQINELQELIK 811
Query: 1385 DELEEERGKIS----ENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXX 1552
+ E + KIS EN +K+Q++N+ L ++ N +
Sbjct: 812 NNGESSKTKISSLLQENTNLNTKIQQLNSLLKQKDDKINDLQNEINDLTQNKIDLEKQIQ 871
Query: 1553 XVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVL 1732
+ + F SK S I+ ++SG + S Q + + +I+++Q L
Sbjct: 872 NLQTIIFDSK------------SQIESLNEKISGLQQLLKSSQETIDSLNDKIKQTQIEL 919
Query: 1733 QSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETL--RAFVKNIQNQVAVSQ 1906
Q + EKL ND E + Y L K+D+ R +K + + ++
Sbjct: 920 QESKDFAEKLQNDINEE------KKKTEDYQL--KLDDIDRLTKERNLLKETEKSLTLTN 971
Query: 1907 EQHIEHQCK-----EELEGHIADL-VLNDFSNDILSWSRRKEEAVVHD-DEFD-AERI-- 2056
++++ K E+L I+ L D ND++S +K+E + D +F+ +E++
Sbjct: 972 AENMQTIDKLKDEIEQLNDKISQLNTTIDQLNDVIS---KKDEEIKQDLQKFELSEKVHQ 1028
Query: 2057 ALLNELKSL---HQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGK 2227
A +N+ + H++ L EE K N + K L E K + DV K
Sbjct: 1029 AAINDYQKQLEHHEEQITLLEEEIEKISKENSDLKAK------ILENEAKLDDFDDV-SK 1081
Query: 2228 SRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRN 2407
+ + Q E E SE EE KL + D ++ +N
Sbjct: 1082 QNSEYKAKIEQLEEELADYESNLQKLSEENGNLEIQIEEIKLKTV---PNTDFNELRTKN 1138
Query: 2408 WPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLL--LNEKNGLHAXXXXXXXXXX 2581
E + K+ A ++ + +K +EI L + + L N L
Sbjct: 1139 TDLEAQIRELKRLLANDDGNKQV-IAQKDKEILSLNQTIIDLQHNNQLLNDKIKDIEMTK 1197
Query: 2582 XXVAEITGKFEKVLQ--ENKLLPVEEVQRYKMLCVLK--------EELQSKIDSLLKEIK 2731
E + +++ Q E+ + + ++Q L LK + L++++ SL E +
Sbjct: 1198 TNYPERSFNNDELHQTIEDNNVSMFDMQNKLNLANLKLKQSEKEIQNLKNELLSLQSENE 1257
Query: 2732 EKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFV 2911
E +S +L + L+ K++ + +S +K+ + +E + ++ + L V
Sbjct: 1258 EMNSTINMLKQSLTS--KENEINELNDSVTVKN-SQIEEILKKNQVKFDKTGNKEQQLQV 1314
Query: 2912 ---------EMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQ 3064
++++EK ++ K + + + L+K D + + + ++ KR+
Sbjct: 1315 LNSSLKHSNDIIQEKGKTIDSQNKLIKNLEDTKQKLQKQNFDLQNNVSNLTNDLEKTKRE 1374
Query: 3065 IAILEKLK----EETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDI 3232
+ L+ K ++ E + Q E KI E+K + + L+N I K ++I
Sbjct: 1375 LLSLQNSKNDNIKQLEQEKELILKQKENENKISEEK--IKNLTLQISNLQNTISQKDNEI 1432
Query: 3233 DSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEI 3412
+ + +K++ +L + +NL + + NE+ E
Sbjct: 1433 QNNLQNLQKVSNEL----DFIKNSTKDHENDLTEKEDVINNLRKLFDDKMKENEKKTKEF 1488
Query: 3413 EKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAV----LVEKLFEGEQKILLLESSQSAT 3580
+ + DL+I + E N+ + + Q+ + + + + F+GE K
Sbjct: 1489 QDSLREKDLMISQLE--NKTMFFDQQMKSKDDKIDSLQIQNVTFQGELK----------- 1535
Query: 3581 REQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENL 3760
E L+NSL ++ +L+K+ S +ELQ+++++L+ + + + L+ K+ +E +
Sbjct: 1536 ----EIQNKLINSL-KQIDELQKENESFQKELQTRDQNLDDSHKQIEELQAKIDQYEEEI 1590
Query: 3761 KEKDLQLRAFE--IANSEKQYQT 3823
K KD L + I N E + +T
Sbjct: 1591 KSKDENLNNLQNKINNYENESKT 1613
Score = 70.9 bits (172), Expect = 4e-09
Identities = 92/452 (20%), Positives = 195/452 (43%), Gaps = 52/452 (11%)
Frame = +2
Query: 2615 KVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSA 2794
K+ +EN LL E EEL S+++ + KE + S+ + L +L + K A
Sbjct: 522 KMKRENSLLKSEN-----------EELVSRVNQIKKENTQLKSDIQDLNNQLRNKKKDFA 570
Query: 2795 DHAQRESHLLKHIADLEAGITDREIMTSV--CSDVLTALFVEMVREKEFSLS---LATKE 2959
Q + +++K + + EI + SD + ++ ++KE + L ++
Sbjct: 571 GSVQNQLNIIKLFLNKLFADFNYEIQKTKQKISDEFLTILRKLQQQKENETNKTKLLERQ 630
Query: 2960 QETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAI---------------LEKLKEE 3094
+ Q+ M L+ + D L + +EN+ H +QI+ + K KE+
Sbjct: 631 INDLKQENMKLKDKINDLQNNLQKILQENENHSKQISTHIDGLSQSIKERDDQILKDKEK 690
Query: 3095 TENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQN-KHSDIDS-LREEQEKLNK 3268
EN ++ + +E + +E+ ++ Q Q+ ++L ++++N K +D+ L +++L K
Sbjct: 691 IENLQNKI--KGKEIDFDQEKSNLIKQNEQKMKDLTDEMENLKRKLLDNELDVVKDQLQK 748
Query: 3269 QLRCMXXXXXXXXXXXXXXXXXXXXISSNLDS------------------MQLELRNYNE 3394
+ + I+ NL+ +Q ++ E
Sbjct: 749 EKQKSQDLEEKIEEKDSTIQILKEKINENLEESKKSYDKLMNDKQEEIALLQKQINELQE 808
Query: 3395 ELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQS 3574
+KN E T I L++E LN ++ ++QK+ +K+ + + +I L ++
Sbjct: 809 LIKNNGESSKTKISSLLQENTNLNTKIQQLNSLLKQKD----DKINDLQNEINDLTQNKI 864
Query: 3575 ATREQTEKYRDL-------LNSLTEEHADLKKQFLSATEELQS---KERDLEVAMTETKF 3724
+Q + + + + SL E+ + L++ S+ E + S K + ++ + E+K
Sbjct: 865 DLEKQIQNLQTIIFDSKSQIESLNEKISGLQQLLKSSQETIDSLNDKIKQTQIELQESKD 924
Query: 3725 LKEKLL--VSDENLKEKDLQLRAFEIANSEKQ 3814
EKL +++E K +D QL+ +I K+
Sbjct: 925 FAEKLQNDINEEKKKTEDYQLKLDDIDRLTKE 956
>ref|XP_001318285.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121901040|gb|EAY06062.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 2416
Score = 148 bits (374), Expect = 2e-32
Identities = 250/1249 (20%), Positives = 497/1249 (39%), Gaps = 73/1249 (5%)
Frame = +2
Query: 263 TSFIEVEDGGLDTRKSLETKIAETLERMEIHEG--DTANTLKNMNFDLGQDNPGVPGLLE 436
T ++++ + +T + +I E +R+ EG + L N +L ++N + L+
Sbjct: 712 TEYLKLIEEKRETDEKYNKEIEELKDRINRGEGGDEVVEELAKENDELSKENEELKEKLK 771
Query: 437 DIRNTKDL------LDTVESGLYVSNVVSDAVLNGV---VSAQEEEFKEALAAKDSENFL 589
DI++++++ ++ +E L + N + + EEE E L K+ E
Sbjct: 772 DIKSSEEIEELTNQIEELEKELNEKKEQLEQTENELTQQIEEIEEEKSEELKKKNEEIER 831
Query: 590 LNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQK 769
L +IE+LN +I SL E + +E + ++ + I E L+++ +++QE +++
Sbjct: 832 LQNEIEELNKEIKSLTEEIDDLQEKLENAKKEIQE----LQEY-------AEKSQENDKQ 880
Query: 770 LASRDNEMMHMVLE---KDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQI 940
E + + E D+ L + E Q L+ EI D I+ E K +
Sbjct: 881 TIDELKEKLRLANETKVTDSDTKVLVESKEAAEQKVLLLE----KEISDLKIEIEDLKSV 936
Query: 941 VETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAE-ISKLSHTLEE-- 1111
++ ++ E+ + LES EI LK E + E I KL +E+
Sbjct: 937 IDEENEQKVSNTEAENRIHELES-----EISELKKELDQNNNQQNDEKIEKLQKEIEDLK 991
Query: 1112 SIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSY-----IDSLASRIDFLSSEC 1276
S+++ E + EN EL +IS+L+ ++ N+ I+ L I+ L +E
Sbjct: 992 SVIDEENEQKVSNTEAENRIHELESEISELKKELDQNNNQQNDEKIEKLQKEIEDLKNEL 1051
Query: 1277 NKLQEQXXXXXXXXXXXXXXXXTLKASMEMQ-------------CSKLKDELEEERGKIS 1417
+ + K ++E Q KL +EE R K+
Sbjct: 1052 ESSKAENEELQNEFEKEIDQISQEKQNLESQIKYLQEKGDKSEIIDKLNQTIEELRAKVE 1111
Query: 1418 ENL------ERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGS 1579
E S+++ + EL+ KS+ + +
Sbjct: 1112 HMFTQEDIDEYKSEIENLKQELSNIEKSKQ-------------------ISEEKSQDYEE 1152
Query: 1580 KLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFE----S 1747
+ EL +++ + + K +++ I +L+ ++N + E+E +K S + S
Sbjct: 1153 IVHELENKLEAKETELSKLKSDFEQQTREIETLKENITNLENEMEIEKKNRNSADNEKIS 1212
Query: 1748 HIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIE-- 1921
H+EK ++D +++ S N ++ K + ++A + I+ + + + + IE
Sbjct: 1213 HLEKQISDLQNKLQDKIKSQN----EMVEKFKRDFQEMQAKDQKIREEESHASQAKIESL 1268
Query: 1922 ----HQCKEE-----LEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNEL 2074
Q KEE + I +++F+ D+ + KE+ + + + E+
Sbjct: 1269 NALLKQSKEENDALKMNHEIKLNKISEFTKDLEQKVKSKEQEI---ELLTQQNSVCSKEI 1325
Query: 2075 KSLHQ-DLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQE----GKDGEASDVQGKSRAL 2239
LH+ + EL K + ++S +N + K + + +QE D + +++ K L
Sbjct: 1326 NDLHKNNSELKKLSDELQSENNVLEEKLKRLMSELKFLQETSVKNTDNQITNLNSKISEL 1385
Query: 2240 RRHSTGQAFREPPKPEDLYTTYSE-GKIVEPHPTEEKKLLAILAFETADASDSPLRNWPK 2416
+E +++ SE KI++ + +L+ +D D +N
Sbjct: 1386 SEEINILKEKEIKLTKEIEKVTSEKNKIIQDNEEVVNQLM-------SDLEDLRRKNINL 1438
Query: 2417 EQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEK----------NGLHAXXXXX 2566
++L+ + ++ + K +YE + + E I L + K + L
Sbjct: 1439 DELVENLRKEISEEKSKYERDTTKLNETILQLNNTVFEIKKQNEQLNLTISDLSTSNNLN 1498
Query: 2567 XXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSN 2746
+ E+ K K +EN L ++ E SK+ ++E K K+ N
Sbjct: 1499 SEKVTQEILELNEKISKAKEENDNLS-RHIEELNQQLESANEENSKLSKTIEEEKTKNLN 1557
Query: 2747 SKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVRE 2926
S +EK S +L+K + Q E + ++ E E+ T +E+ +E
Sbjct: 1558 S---SEK-SFSLEKEVEKLQEEKEIFVEKSEEEKNKLKSEVTTLTEISANLKQEIEISKE 1613
Query: 2927 KEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENN 3106
+ L E E+ N++ L+ +E+ + + +N + ++QI L K EE +
Sbjct: 1614 QNEKLKSMLSEVESNNEE---LKHTIEELSSQINDLQTQNDKVEKQIENLNKTIEEKDET 1670
Query: 3107 PGRVFLQSEEREKIE-EQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCM 3283
++ S++ EK + E K + ++ + EL I++K S+ D L E + LNK+ +
Sbjct: 1671 INKMIANSDDSEKRDNEMKELFNKQNNKINELSKLIESKTSENDKLLSEIKDLNKENEEL 1730
Query: 3284 XXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEEL 3463
S ++ +L + +L + E + ID L K E
Sbjct: 1731 AVLVDEKEDENHTLQVRIDEKDSENSQLKTDLSDIENKLNSGKELLNHTIDELTKSIESK 1790
Query: 3464 NERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADL 3643
+ + A++Q + K E + KI E + E K D LN + EE
Sbjct: 1791 SNENSKLMSAIDQ-----LNKDLENKNKI--TEEIANKNEENESKLLD-LNKVVEELKKQ 1842
Query: 3644 KKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAF 3790
+ L E + ++ D E + E +KEK + D+ K+ D Q+ F
Sbjct: 1843 LEHVLIDNESEKQEKSDTEQKLREEIEIKEKEI--DKLKKQNDQQIDHF 1889
Score = 110 bits (274), Expect = 6e-21
Identities = 234/1252 (18%), Positives = 499/1252 (39%), Gaps = 133/1252 (10%)
Frame = +2
Query: 452 KDLLDTVESGLYVSNV--VSDAVLNGVVSAQEE---EFKEALAAKDSENF--LLNKKIED 610
K+L+ T+++ L + + + L ++ ++E +F + + ENF LLN
Sbjct: 496 KELIRTIKAHLSMGELKDIMKWYLKTIIDSEESTWNKFVQKIMFILDENFDNLLNDTEIQ 555
Query: 611 LNH---------KIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETE 763
+N +I LE+ + +++I + E + + LL++ H ++ Q + ET
Sbjct: 556 VNDSALVSIQKARIDELEKKFEQTQQIIDENKE-LKDTLNLLQEEFHAYEMTIQ-SYETT 613
Query: 764 QKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIV 943
+++N+ + LE I +++ + + +N L D + + E +Q+
Sbjct: 614 LNEKNQENDKLRQKLESKGIF---NQETDKKDENEIKLKQLNEDYENYKKVTNEKIQQLE 670
Query: 944 ETIYVTQIQELGEEHD-----LLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLE 1108
T Q Q + +L+ E+ +YQ +I LKD + E KL
Sbjct: 671 NTKRQLQEQINNQPKPEGNLAMLQKENEEYQRQINELKD--------LKTEYLKLIEEKR 722
Query: 1109 ESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQ 1288
E T E Y EL D+I N + ++ LA D LS E +L+
Sbjct: 723 E-----------TDEKYNKEIEELKDRI----NRGEGGDEVVEELAKENDELSKENEELK 767
Query: 1289 EQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERI----------- 1435
E+ +E + ++ K++LE+ ++++ +E I
Sbjct: 768 EKLKDIKSSEEIEELTNQI--EELEKELNEKKEQLEQTENELTQQIEEIEEEKSEELKKK 825
Query: 1436 -SKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSK------LEEL 1594
+++++ NE+ E +K S+ + A S+ ++EL
Sbjct: 826 NEEIERLQNEIEELNKEIKSLTEEIDDLQEKLENAKKEIQELQEYAEKSQENDKQTIDEL 885
Query: 1595 TDQINIFNS----------VIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFE 1744
+++ + N +++ KEA + L+ +S+ K EIE + V+ E
Sbjct: 886 KEKLRLANETKVTDSDTKVLVESKEAAE----QKVLLLEKEISDLKIEIEDLKSVID--E 939
Query: 1745 SHIEKLVN----DSLHEVDSAFCSLNSRF-YSLIHKVDNSGETLRAFVKNIQNQVAVSQE 1909
+ +K+ N + +HE++S L + + D E L+ ++++++ + E
Sbjct: 940 ENEQKVSNTEAENRIHELESEISELKKELDQNNNQQNDEKIEKLQKEIEDLKSVIDEENE 999
Query: 1910 QHIEHQCKE----ELEGHIADL---------------------VLNDFSNDILSWSRRKE 2014
Q + + E ELE I++L + D N++ S E
Sbjct: 1000 QKVSNTEAENRIHELESEISELKKELDQNNNQQNDEKIEKLQKEIEDLKNELESSKAENE 1059
Query: 2015 EAVVHDDEFDAERIALLNELKSLHQDLELLKAE----EAVKSLSNNV-GVSTKGIHYFSQ 2179
E +EF+ E + E ++L ++ L+ + E + L+ + + K H F+
Sbjct: 1060 EL---QNEFEKEIDQISQEKQNLESQIKYLQEKGDKSEIIDKLNQTIEELRAKVEHMFT- 1115
Query: 2180 LIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLA 2359
QE D S+++ + L + E + + +E TE KL +
Sbjct: 1116 --QEDIDEYKSEIENLKQELSNIEKSKQISEEKSQDYEEIVHELENKLEAKETELSKLKS 1173
Query: 2360 ILAFETADAS---------------DSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKT 2494
+T + + RN + + H ++ + L+ + + +++ +
Sbjct: 1174 DFEQQTREIETLKENITNLENEMEIEKKNRNSADNEKISHLEKQISDLQNKLQDKIKSQN 1233
Query: 2495 EEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKML 2674
E + KR + + + ++ +EN L + + +
Sbjct: 1234 EMVEKFKRDFQEMQAKDQKIREEESHASQAKIESLNALLKQSKEENDALKMNHEIKLNKI 1293
Query: 2675 CVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSD------ALKKSADHAQRESHL----- 2821
++L+ K+ S +EI+ + V +++++D LKK +D Q E+++
Sbjct: 1294 SEFTKDLEQKVKSKEQEIELLTQQNSVCSKEINDLHKNNSELKKLSDELQSENNVLEEKL 1353
Query: 2822 ------LKHIADLEAGITDREI--MTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQ 2977
LK + + TD +I + S S++ + +++EKE L TKE E V
Sbjct: 1354 KRLMSELKFLQETSVKNTDNQITNLNSKISELSEE--INILKEKEIKL---TKEIEKVTS 1408
Query: 2978 KQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQ 3157
++ K+++D ++++ + + ++ +R+ L++L E SEE+ K E
Sbjct: 1409 EK---NKIIQDNEEVVNQLMSDLEDLRRKNINLDELVENLRKE------ISEEKSKYERD 1459
Query: 3158 KRVLDQALQECEELKNDIQNKHSDID-SLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXX 3334
L++ + + +I+ ++ ++ ++ + N +
Sbjct: 1460 TTKLNETILQLNNTVFEIKKQNEQLNLTISDLSTSNNLNSEKVTQEILELNEKISKAKEE 1519
Query: 3335 XXXISSNLDSMQLELRNYNEE---LKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQK 3505
+S +++ + +L + NEE L IE++ T +L EK E+ +K E+K
Sbjct: 1520 NDNLSRHIEELNQQLESANEENSKLSKTIEEEKTK-NLNSSEKSFSLEK--EVEKLQEEK 1576
Query: 3506 EAVLVEKLFEGEQKI-----------LLLESSQSATREQTEKYRDLLNSLTEEHADLKKQ 3652
E + VEK E + K+ L+ ++EQ EK + +L+ + + +LK
Sbjct: 1577 E-IFVEKSEEEKNKLKSEVTTLTEISANLKQEIEISKEQNEKLKSMLSEVESNNEELK-- 1633
Query: 3653 FLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSE 3808
EEL S+ DL+ T+ +++++ ++ ++EKD + IANS+
Sbjct: 1634 --HTIEELSSQINDLQ---TQNDKVEKQIENLNKTIEEKDETINKM-IANSD 1679
Score = 102 bits (253), Expect = 2e-18
Identities = 237/1181 (20%), Positives = 459/1181 (38%), Gaps = 90/1181 (7%)
Frame = +2
Query: 542 EEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFI 721
E K+ L+ + + +K +D + LE L+ KE + ++ R ++
Sbjct: 1127 ENLKQELSNIEKSKQISEEKSQDYEEIVHELENKLEAKETELSKLKSDFEQQTREIETLK 1186
Query: 722 HEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRD-- 895
++ + ++ S DNE + LEK L Q +++SQN + ++ F+RD
Sbjct: 1187 ENITNLENEMEIEKKNRNSADNEKISH-LEKQISDLQNKLQDKIKSQN-EMVEKFKRDFQ 1244
Query: 896 --EIEDQNIKEE---IEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAK 1060
+ +DQ I+EE + +E++ +++ EE+D L++ ++I + K
Sbjct: 1245 EMQAKDQKIREEESHASQAKIESLNAL-LKQSKEENDALKMNHEIKLNKISEFTKDLEQK 1303
Query: 1061 EMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSK------ 1222
SK+ EI L T + S+ + + L + ++L D++ N + K
Sbjct: 1304 VKSKEQEIELL--TQQNSVCSKEINDLHKNN---SELKKLSDELQSENNVLEEKLKRLMS 1358
Query: 1223 -------------NSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASME 1363
++ I +L S+I LS E N L+E+ + E
Sbjct: 1359 ELKFLQETSVKNTDNQITNLNSKISELSEEINILKEKEIKLTKEIEKVTSEKNKIIQDNE 1418
Query: 1364 MQCSKLKDELEEERGK------ISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXX 1525
++L +LE+ R K + ENL + +K E + +K +I
Sbjct: 1419 EVVNQLMSDLEDLRRKNINLDELVENLRKEISEEKSKYE-RDTTKLNETILQLNNTVFEI 1477
Query: 1526 XXXXXXXXXXVVNMAFGSKL--EELTDQINIFNSVIDKKEAE---VSGHLDTI------- 1669
+ +++ + L E++T +I N I K + E +S H++ +
Sbjct: 1478 KKQNEQLNLTISDLSTSNNLNSEKVTQEILELNEKISKAKEENDNLSRHIEELNQQLESA 1537
Query: 1670 ----SSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHK 1837
S L + +K + S + S E +EKL + V+ + N K
Sbjct: 1538 NEENSKLSKTIEEEKTKNLNSSEKSFSLEKEVEKLQEEKEIFVEKSEEEKN--------K 1589
Query: 1838 VDNSGETLRAFVKNIQNQVAVSQEQHIEHQC--------KEELEGHIADLVLNDFSNDIL 1993
+ + TL N++ ++ +S+EQ+ + + EEL+ I +L + ND+
Sbjct: 1590 LKSEVTTLTEISANLKQEIEISKEQNEKLKSMLSEVESNNEELKHTIEEL--SSQINDLQ 1647
Query: 1994 SWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYF 2173
+ + + E+ + + ++ E+ +N++ + D E K + +K L N I+
Sbjct: 1648 TQNDKVEKQIENLNKTIEEKDETINKMIANSDDSE--KRDNEMKELFNK---QNNKINEL 1702
Query: 2174 SQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKL 2353
S+LI E K E + + + L + + A K ++ +T ++ +E +L
Sbjct: 1703 SKLI-ESKTSENDKLLSEIKDLNKENEELAVLVDEKEDENHTLQVR---IDEKDSENSQL 1758
Query: 2354 LAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNE 2533
D SD + ++LL H E + I L + L N+
Sbjct: 1759 -------KTDLSDIENKLNSGKELLNHTIDELTKSIESKSNENSKLMSAIDQLNKDLENK 1811
Query: 2534 KNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDS 2713
EI K E+ E+KLL + +V LK++L+ +
Sbjct: 1812 NK---------------ITEEIANKNEE--NESKLLDLNKVVEE-----LKKQLEHVLID 1849
Query: 2714 LLKEIKEKDSNSKVLAEKLS------DALKKSADHAQRESHLLKHIADLEAGITDREIMT 2875
E +EK + L E++ D LKK D Q+ H I+ + + +
Sbjct: 1850 NESEKQEKSDTEQKLREEIEIKEKEIDKLKKQND--QQIDHFTTQISQINDDHNNE--ID 1905
Query: 2876 SVCSDVLTALF-VEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKE 3052
+ D T + ++ E+E + K +E + S ++ +ED + +G +N E
Sbjct: 1906 QINEDYQTQIDQIKHDHEREMN-----KLKENHQHEIESYKQNIEDLEHQFKEIGCKNDE 1960
Query: 3053 HKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQA-LQECEELKNDIQNKHSD 3229
+ + K + E V S+ E E K ++Q ++ EE+ S
Sbjct: 1961 YFNNLIDQINTKNKEEIEKLNVQFTSQISEINENHKNEIEQINIKNQEEIMKINYQFTSQ 2020
Query: 3230 IDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNY---NEEL 3400
I L E +E+ NK++ + +D + E+ Y N +
Sbjct: 2021 ISELNELKEEDNKKIYELCQDNSEK--------------KKEIDRLNKEIEEYHNMNHQR 2066
Query: 3401 KNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQK------ILLLE 3562
+N+ EK + D +I ++LN+ + Q+ ++ L EK E+ I L+
Sbjct: 2067 ENDNEKNLIEKDEII---QKLNKTIKDKQREIDCLNDQLTEKDESSEENDKLVKFISTLK 2123
Query: 3563 SSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEV-------AMTETK 3721
S S+ ++ + + + +++ DLK ++ Q+ E D+E+ TE K
Sbjct: 2124 ESLSSKEKEIQNLKKQNEEILKQNNDLKSLNEQQNDDKQNNENDIEIMKKEIMKLRTENK 2183
Query: 3722 FLKE----------KLLVSDENLKEKDLQLRAFEIANSEKQ 3814
LK KL S EN + + +L+ E+ N KQ
Sbjct: 2184 DLKNQVSQQHKALVKLAKSLENKNKAEEKLKQ-ELQNISKQ 2223
Score = 95.1 bits (235), Expect = 2e-16
Identities = 184/960 (19%), Positives = 392/960 (40%), Gaps = 62/960 (6%)
Frame = +2
Query: 482 LYVSNVVSDAVLNGVVSAQEE-EFKEALAAKDSENFLLNKKIEDLNHKIWS-------LE 637
L +S++ + LN QE E E ++ EN L++ IE+LN ++ S L
Sbjct: 1486 LTISDLSTSNNLNSEKVTQEILELNEKISKAKEENDNLSRHIEELNQQLESANEENSKLS 1545
Query: 638 ETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKD 817
+T++ ++ L+S E ++ ++ EK++ ++++E + KL S V
Sbjct: 1546 KTIEEEKTKNLNSSEKSFSLEKEVEKLQEEKEIFVEKSEEEKNKLKSE-------VTTLT 1598
Query: 818 NIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLL 997
I +L ++IE+ + + L E+E N EE++ I E +QI +L ++D +
Sbjct: 1599 EISANLKQEIEISKEQNEKLKSML-SEVESNN--EELKHTIEELS--SQINDLQTQNDKV 1653
Query: 998 RLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRE 1177
+ I+ KDE K ++ + K + ++E N + +++ E+ E
Sbjct: 1654 EKQIENLNKTIEE-KDETINKMIANSDDSEKRDNEMKELFNKQNNKINELSKLIESKTSE 1712
Query: 1178 LGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQ----EQXXXXXXXXXXXXXXXXT 1345
+S+++ D+ +N + LA +D E + LQ E+
Sbjct: 1713 NDKLLSEIK-DLNKEN---EELAVLVDEKEDENHTLQVRIDEKDSENSQLKTDLSDIENK 1768
Query: 1346 LKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXX 1525
L + E+ + + + K +EN + +S + ++N +L ++K I
Sbjct: 1769 LNSGKELLNHTIDELTKSIESKSNENSKLMSAIDQLNKDLENKNKITEEIANKNEENESK 1828
Query: 1526 XXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKF 1705
+ +EEL Q+ V+ E+E DT L+ + ++
Sbjct: 1829 L------------LDLNKVVEELKKQLE---HVLIDNESEKQEKSDTEQKLREEIEIKEK 1873
Query: 1706 EIEKSQKV----LQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGET-LRAF 1870
EI+K +K + F + I ++ +D +E+D +N + + I ++ + E +
Sbjct: 1874 EIDKLKKQNDQQIDHFTTQISQINDDHNNEIDQ----INEDYQTQIDQIKHDHEREMNKL 1929
Query: 1871 VKNIQNQVAVSQE--QHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFD 2044
+N Q+++ ++ + +EHQ KE G D N+ + I + + KEE + +F
Sbjct: 1930 KENHQHEIESYKQNIEDLEHQFKEI--GCKNDEYFNNLIDQINT--KNKEEIEKLNVQFT 1985
Query: 2045 AERIALLNELKSLHQDLELLKAEEAVK-------SLSNNVGVSTKGIHYFSQLIQEGKDG 2203
++ + K+ + + + EE +K +S + + +L Q+ +
Sbjct: 1986 SQISEINENHKNEIEQINIKNQEEIMKINYQFTSQISELNELKEEDNKKIYELCQDNSE- 2044
Query: 2204 EASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETAD 2383
+ ++ ++ + + RE ++L + + ++++ + L + +
Sbjct: 2045 KKKEIDRLNKEIEEYHNMNHQRENDNEKNLIEKDEIIQKLNKTIKDKQREIDCLNDQLTE 2104
Query: 2384 ASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXX 2563
+S N + + K+S + ++E + L+++ EEI N+ L+
Sbjct: 2105 KDESSEENDKLVKFISTLKESLSSKEKEIQ-NLKKQNEEILKQN----NDLKSLNEQQND 2159
Query: 2564 XXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKI------------ 2707
+ + + K+ ENK L + Q++K L L + L++K
Sbjct: 2160 DKQNNENDIEIMKKEIMKLRTENKDLKNQVSQQHKALVKLAKSLENKNKAEEKLKQELQN 2219
Query: 2708 -----------DSLLKEIKEKDSNSKVLAEKLSDALKKSA-------DHAQRESHLLKHI 2833
D L +K+KD+ + ++L++AL+K+A ++ + K I
Sbjct: 2220 ISKQNIVKNEEDKLTLLVKDKDNQLQRCRKELTNALQKAALYRAGLRSSQKQIIEIKKEI 2279
Query: 2834 ADLEAGITDREIMTSVCSDVLT--ALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLE 3007
D ++ ++ +I+ C + AL + + + E E +N + SL K L+
Sbjct: 2280 EDFKSSVSSEDILHERCLFLRARPALLAALTETETQKGEIEAVELE-LNDTKDSLAKALK 2338
Query: 3008 DKDKLLCLVGEENKE----HKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQ 3175
D L + E K K I + EK+KE+ RE+IEE+ + L++
Sbjct: 2339 DNRDLSSHIVEMRKTIKLLKKTAITLEEKVKEKDSG-----------REQIEEKVKELEK 2387
>ref|XP_005159740.1| PREDICTED: titin isoform X3 [Danio rerio]
Length = 15590
Score = 145 bits (365), Expect = 2e-31
Identities = 243/1187 (20%), Positives = 477/1187 (40%), Gaps = 102/1187 (8%)
Frame = +2
Query: 539 EEEFKEALAAKD---SENFLLNKKIEDLNHKIWSLE---ETLQYKEEVILSSHETISERD 700
E + KE L K+ S+ LL K +E+L K+ +E E+L+ E++ + E + +
Sbjct: 3628 EIQMKEVLTEKELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMK 3687
Query: 701 RLLKDFIHEKDLM----QQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNT 868
L+ E + + Q Q E+ A + ++ DNI +H + Q
Sbjct: 3688 TDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMK 3747
Query: 869 QSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDE 1048
Q D + + E QN+++E+EK+ + I + EL + L + D I+++K+E
Sbjct: 3748 QKQDELDQLKTEIQNLQQELEKE--KEIIMKDRSELDLKQSELDKQQTNMNDIIETMKNE 3805
Query: 1049 CHAKEMSKQA------EISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRND 1210
+ K+ EI K H ++ NS E L ++ + F E +++ Q++ +
Sbjct: 3806 RKQLDKDKEEMEEQKREIEKEKHDFDQG-RNSLDEDLKMMKLQKQVFEEEKNKLEQMKIE 3864
Query: 1211 MYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDE 1390
L E +++ K+K+E
Sbjct: 3865 -----------------LEREAGEIR-----------------------------KIKEE 3878
Query: 1391 LEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMA 1570
++ ER + + E + + ++ LAE +K + I
Sbjct: 3879 IQNERQSLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEK------ 3932
Query: 1571 FGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESH 1750
S EE+ + I+ + K+ + D + LQ + Q+ EIEK + ++S +
Sbjct: 3933 --SNFEEMRENISKQTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAA 3990
Query: 1751 IEKLVNDSLHEVDSAFCSLNSRFYSL---IHKVDNSGETLRAFVKNIQNQV----AVSQE 1909
I K+V D H++ SL+ SL +N E L+ ++ + + E
Sbjct: 3991 IIKIVEDLQHKI----ISLDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLE 4046
Query: 1910 QHIEHQCKEELEGHIA----------------DLVLNDFSNDILS--WSRRKEEAVVHDD 2035
+ Q EE+ I D+VLN+ + DI S + ++ ++ +
Sbjct: 4047 TQHDRQRVEEMTAQITKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKE 4106
Query: 2036 EFDAERIALLNELKSLHQDL---------ELLKAEEAVKSLSNNVGVSTKGIHYFSQLI- 2185
+ + E+ +EL + +DL E+ K E ++ ++ N+ + I + + +
Sbjct: 4107 KHNLEKTR--SELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQMK 4164
Query: 2186 --QEGKDGEASDVQGKSRALRRHS-------------TGQAFREPPKPEDLYTTY-SEGK 2317
Q+ D +++Q + L + + ++ D+ T +E K
Sbjct: 4165 QKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNERK 4224
Query: 2318 IVEPHPTEEKKLLAILAFETADASDSPLRNWPKE-QLLGHFKQSFAGLKREYE---LELQ 2485
+++ E ++ + E D D +++ ++ +++ KQ K + E ELQ
Sbjct: 4225 LLDKDKEEMEEQKQEMEKE-RDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQ 4283
Query: 2486 RKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXV--AEITGKFEKVLQENKLL---PVE 2650
R+ +EI +K NE+ L V AE T + +++L E ++ +
Sbjct: 4284 READEIRKIKEETQNERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMA 4343
Query: 2651 EVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKH 2830
++QR K + EE++ I ++I+ + SK+ ++L L+ Q E + K
Sbjct: 4344 DLQREKRIL---EEMRENISKQTEDIENEKEKSKLREDELK-KLQTEVQKQQSEIDMEKT 4399
Query: 2831 IADLEAGITDRE---IMTSV--CSDVLTALFVEMVREKEF---SLSLATKEQETVNQKQM 2986
+ E + RE +MT + S+ + E++ EKE +L K+ E + QK M
Sbjct: 4400 NIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLM 4459
Query: 2987 SLRKMLEDKDKLLCLVGEEN---KEHKRQIAI----LEKLKEETENNPGRV-FLQSEERE 3142
S+ + E G E K+ K + I +EK+K ET++ RV + ++ E
Sbjct: 4460 SIERDSESLKLDREAFGNEKEVLKQMKTDLQIQADEIEKIKLETQHERQRVEEMTADFME 4519
Query: 3143 KIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXX 3322
+ +++ L++ +E +E K +++ + D+D + ++ L+K L+ M
Sbjct: 4520 TMNNERKQLNKNKEEMQEQKQEMEKERHDMD---QSRKSLDKNLKMMKLQKQVIEEEKNK 4576
Query: 3323 XXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERL--AYTQKAM 3496
+ D E+R EE +NE ++ + L KEKE T+K +
Sbjct: 4577 LEQMKIELEKEAD----EIRKIKEETQNERQRLEKMTEELKKEKESFTHLAEDTKTEKKI 4632
Query: 3497 EQKEAVLVEKLFEGEQK----ILLLESSQSATREQTEKYRDLL----NSLTEEHADLKKQ 3652
K V E L QK + + + S E +EK ++ + + L + A++ KQ
Sbjct: 4633 LDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQLQAEIHKQ 4692
Query: 3653 FLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFE 3793
E + E + + + K L+ K+ D +L+ L AFE
Sbjct: 4693 QGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRDLESLKLDREAFE 4739
Score = 132 bits (332), Expect = 1e-27
Identities = 256/1327 (19%), Positives = 519/1327 (39%), Gaps = 144/1327 (10%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNT 451
IE + L + L E L++M+ A ++ + + + V + I+
Sbjct: 3662 IESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKD 3721
Query: 452 KDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWS 631
++ L + ++ + D + QE++ K+ +++ L +I +
Sbjct: 3722 REYLQKMNDN--ITREIHD------IKYQEKQMKQK-----------QDELDQLKTEIQN 3762
Query: 632 LEETLQYKEEVILSSHETI----SERDRL---LKDFIH---------EKDLMQQRAQETE 763
L++ L+ ++E+I+ + SE D+ + D I +KD + Q+ E
Sbjct: 3763 LQQELEKEKEIIMKDRSELDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKRE 3822
Query: 764 QKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNT--QSLDCFRRDEIEDQNIKEEIEKQ 937
+ D + L++D ++ L KQ+ + +N Q R+ E + IKEEI+ +
Sbjct: 3823 IEKEKHDFDQGRNSLDEDLKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNE 3882
Query: 938 IVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESI 1117
+T+ + +E E K + EI DE S AE+ K EE
Sbjct: 3883 RQSLEKMTEELKREKESFTHLAEDTKKEQEIL---DEIKVANESLMAELQKEKSNFEEMR 3939
Query: 1118 MNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQX 1297
N + ++ EN R D++ QL+ +++ + I+ S I+ + K+ E
Sbjct: 3940 ENISKQTEDVKNKKEN-LRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDL 3998
Query: 1298 XXXXXXXXXXXXXXXTLKASMEMQ---CSKLKDELEEERGKISE-NLERISKLQKMNNEL 1465
+ + E + ++K ELE E +I + LE Q++
Sbjct: 3999 QHKIISLDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMT 4058
Query: 1466 AERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAE 1645
A+ +K ++ K+ L ++ N + V+++K +
Sbjct: 4059 AQITKERD------------------------------KINNLIEETNRKDMVLNEKNRD 4088
Query: 1646 VSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSA---FCSLNSR 1816
+ + +I S + +L +K +EK++ L + +EK ++L E+ +N
Sbjct: 4089 IEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNEN 4148
Query: 1817 FYSLIHKVDNSGET----------LRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADL- 1963
+H++ + E L+ ++N+Q ++ +E+ I + + EL+ ++L
Sbjct: 4149 ITIEMHEIKHQEEQMKQKQDELDQLKTEIQNLQQEL--EKEKEIIMKDRSELDLRQSELD 4206
Query: 1964 --------VLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEA 2119
++ N+ + KEE E + ER + +KSL +DL+++K ++
Sbjct: 4207 KQQTNMNDIIETMKNERKLLDKDKEEMEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQ 4266
Query: 2120 V----KSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPE 2287
V K+ + + + I+E E ++ ++AL + E
Sbjct: 4267 VIEEEKNKLEQMKFELQREADEIRKIKEETQNERQSLEKMTKALIKER-----------E 4315
Query: 2288 DLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQ-LLGHFKQSFAGLKR 2464
DL + + EK++L E A+ S + + +E+ +L +++ +
Sbjct: 4316 DLVH-------LAEYTKREKEMLD----EMQVANKSSMADLQREKRILEEMRENISKQTE 4364
Query: 2465 EYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLP 2644
+ E E ++ +LK+L + +EI + + E ++
Sbjct: 4365 DIENEKEKSKLREDELKKLQTEVQK---------------QQSEIDMEKTNIESERAVMI 4409
Query: 2645 VEEVQRYKMLCVLKEELQSKIDSLL--KEIKEKDSNSKVLAEKLSDALKKSADHAQRESH 2818
E+ L E+++ ++ +L KE+ E DSN L +K + LK+ +R+S
Sbjct: 4410 REKQNMMTELKKKSEDVEIQMKEILTEKELLENDSN---LLKKDMEDLKQKLMSIERDSE 4466
Query: 2819 LLKHIADLEAGITDREIMTSVCSDV-----------------------LTALFVEMVREK 2929
LK D EA ++E++ + +D+ +TA F+E + +
Sbjct: 4467 SLK--LDREAFGNEKEVLKQMKTDLQIQADEIEKIKLETQHERQRVEEMTADFMETMNNE 4524
Query: 2930 EFSLSLATKEQETVNQKQMSLRKMLEDKD-------------KLLCLVGEENKEHKRQIA 3070
L+ K +E + +++ + K D D KL V EE K Q+
Sbjct: 4525 RKQLN---KNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMK 4581
Query: 3071 I--------LEKLKEETENNPGRVFLQSEEREKIEE-----------QKRVLDQALQECE 3193
I + K+KEET+N R+ +EE +K +E +K++LD+ E
Sbjct: 4582 IELEKEADEIRKIKEETQNERQRLEKMTEELKKEKESFTHLAEDTKTEKKILDKMKVANE 4641
Query: 3194 ELKNDIQNKHSDIDSLRE---------EQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXI 3346
L D+Q + S+++ +RE E+EK +LR
Sbjct: 4642 SLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLR----------------------- 4678
Query: 3347 SSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEK 3526
L+ +Q E+ E+K E ++ +IK+ ++L ++ + +E + L +
Sbjct: 4679 EDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRDLESLK--LDRE 4736
Query: 3527 LFEGEQKIL-----------------LLESSQSATR-----EQTEKYRDLLNSLTEEH-- 3634
FE E+++L LE+ R Q +K RD +N+L EE
Sbjct: 4737 AFENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVEEMTAQIQKERDKINNLIEETNR 4796
Query: 3635 -----ADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIA 3799
++K + + ++S LE + + + KLL + ENL EK +++ EI
Sbjct: 4797 KDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENL-EKQRKIKLAEIQ 4855
Query: 3800 NSEKQYQ 3820
+ +
Sbjct: 4856 KEREDLE 4862
Score = 124 bits (310), Expect = 4e-25
Identities = 247/1298 (19%), Positives = 522/1298 (40%), Gaps = 115/1298 (8%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNT 451
IE E L+ K K A+ + +++ + L+ M +L ++ L ED +
Sbjct: 4570 IEEEKNKLEQMKIELEKEADEIRKIKEETQNERQRLEKMTEELKKEKESFTHLAEDTKTE 4629
Query: 452 KDLLDTV-------------------ESGLYVSNVVSDAV---------------LNGVV 529
K +LD + E +S D+ L +
Sbjct: 4630 KKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQLQAEI 4689
Query: 530 SAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLE---ETLQYKEEVILSSHETISERD 700
Q+ E K + +SE + K ++DL HK++SL+ E+L+ E + E + +
Sbjct: 4690 HKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREVLKQIK 4749
Query: 701 RLLKDFIHEKDLMQQRAQETEQKLAS--------RD--NEMMHMVLEKDNIILSLHKQIE 850
LK E + ++ Q Q++ RD N ++ KD ++ + +I+
Sbjct: 4750 TDLKRKAEEIEKIKLETQHDRQRVEEMTAQIQKERDKINNLIEETNRKDMVLNEIKTEIK 4809
Query: 851 LQSQNTQSLDCFRRDEIEDQN------------IKEEIEKQIVETIYVTQIQELGEE--- 985
+ + +S RD +E + KE +EKQ I + +IQ+ E+
Sbjct: 4810 EKIKAIES----DRDMLEKEKHDLEKTRSKLLRAKENLEKQ--RKIKLAEIQKEREDLEK 4863
Query: 986 ---------HDLLRLESA--KYQDEIQSLKDECH--AKEMSKQAEISKLSHTLEESIMNS 1126
HD+ E + QDE+ LK E +E+ K+ EI + + + S
Sbjct: 4864 MNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRS-QLDLRQS 4922
Query: 1127 NLESLFT-----AEIYENTFRELG---DQISQLRNDMYSKNSYIDSLASRIDFLSSECNK 1282
L+ T E +N ++L ++ + + +M + D +D + K
Sbjct: 4923 ELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDE-DLKMMK 4981
Query: 1283 LQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISK-LQKMNN 1459
LQ+Q +A ++ K+K+E++ ER +NLE++++ L++
Sbjct: 4982 LQKQVLEDEKSKLEQMKIELEREA---VEIRKIKEEIQNER----QNLEKMTEALKEERE 5034
Query: 1460 ELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKE 1639
+LAE +K N + S LEE+ + I+ ++ K+
Sbjct: 5035 DLAEETKKNNQVLDEMKVANESTLADILREK--------SNLEEMRENISKQTEDVENKK 5086
Query: 1640 AEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEV-----DSAFCS 1804
+ D + LQ + Q+ EIEK + ++S + I K V D H++ D+
Sbjct: 5087 ENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLK 5146
Query: 1805 LNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFS- 1981
L+ + +N E L+ ++ + ++ +E Q + +A + D
Sbjct: 5147 LDREAF------ENEKEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDE 5200
Query: 1982 -NDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTK 2158
N+++ + RK+ V+++ D E ++KS+ D ++L+ E+ +++ +
Sbjct: 5201 INNLIEETNRKD-MVLNEKNRDIEE-----KIKSIQSDKDMLEKEK------HDLEKTRS 5248
Query: 2159 GIHYFSQLIQEGKDGEASDVQGKSRALRRHSTG----------QAFREPPKPEDLYTTYS 2308
++ + +++ K+ +++Q + L + + Q + K ++L +
Sbjct: 5249 ELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKT 5308
Query: 2309 EGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQR 2488
E + ++ +EK+++ D S LR ++ + +K E + +L +
Sbjct: 5309 EIQNLQQELEKEKEIIM------KDRSQLDLRQSELDKQQTNMNDIMETMKNERK-QLDK 5361
Query: 2489 KTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYK 2668
EE+ + K+ + E++ + + + +K ++ K + EE + +
Sbjct: 5362 DKEEMEEQKQEMEKERDNMDQSR------------KSLDEDQKKMKLQKQMFEEEKNKLE 5409
Query: 2669 MLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDAL---KKSADHAQRESHLLKHIAD 2839
+ K EL+ + D + K IKE+ N + EK+++ L K+S H ++ K I D
Sbjct: 5410 QM---KIELEREADEISK-IKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILD 5465
Query: 2840 LEAGITDREIMTSVCSD--VLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDK 3013
E + + M + + +L + + + KE+ E+E ++ L+K+ +
Sbjct: 5466 -EMKVANESSMADLQREKSILEEMRENISKLKEY----IDNEKEKSKLREDELKKLQTEV 5520
Query: 3014 DKLLCLVGEE--NKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQE 3187
K + E N E +R I EK + +E ++K E+ + + + L E
Sbjct: 5521 QKQQSKIDMEKTNIESERAAMIREKQN-----------MMTELKKKSEDVEIQMKEILTE 5569
Query: 3188 CEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSM 3367
E L ND + D+++L+++ L + + + + D +
Sbjct: 5570 KELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEI 5629
Query: 3368 QLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQK 3547
+ +++ + + +E+ + I KE++++N + T + K+ VL EK + E+K
Sbjct: 5630 E-KIKLETQHDRQRVEEMAAQIQ---KERDKINNLIEETNR----KDMVLNEKNRDIEEK 5681
Query: 3548 ILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEV-------A 3706
I ++S + ++ + L + DL+KQ + E+Q + D+E
Sbjct: 5682 IKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENITRE 5741
Query: 3707 MTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQYQ 3820
M E K +E++ N K+ +L EI N +++ +
Sbjct: 5742 MHEIKHQEEQM-----NQKQDELDQLKTEIQNLQQELE 5774
Score = 122 bits (307), Expect = 9e-25
Identities = 261/1290 (20%), Positives = 533/1290 (41%), Gaps = 129/1290 (10%)
Frame = +2
Query: 296 DTRKSLETKIAETLERMEIH----EGDTANTLK---NMNFDLGQDNPGVPGLLEDIRNTK 454
D K L+T++ + ++++ E + A ++ NM +L + + V +++I K
Sbjct: 5511 DELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEIQMKEILTEK 5570
Query: 455 DLLDTVESGLY--VSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIW 628
+LL L V N+ + + + K A ++E + + DL +
Sbjct: 5571 ELLHNDRKLLTRDVENLQQKLI---DLERDSKRLKLDREAFENEKEAMKQMKTDLQIQAD 5627
Query: 629 SLE----ETLQYKEEVILSSHETISERDRL--LKDFIHEKDL-MQQRAQETEQKLASRDN 787
+E ET ++ V + + ERD++ L + + KD+ + ++ ++ E+K+ S +
Sbjct: 5628 EIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQS 5687
Query: 788 EMMHMVLEKDNI------ILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVET 949
+ + E+ N+ + + + +E Q +NT + R+++E N E I +++ E
Sbjct: 5688 DKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKMN--ENITREMHEI 5745
Query: 950 IYVT-QIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMS----KQAEISKLSHTLEES 1114
+ Q+ + +E D L+ E Q E++ K E K+ S +Q+E+ K +++
Sbjct: 5746 KHQEEQMNQKQDELDQLKTEIQNLQQELEKEK-EIIMKDRSQFDLRQSELDK-----QQT 5799
Query: 1115 IMNSNLESLFTAEIYENTFRELG---DQISQLRNDMYSKNSYIDSLASRIDFLSSECNKL 1285
MN +E++ +N ++L +++ + + +M + D +D + KL
Sbjct: 5800 NMNDIMETM------KNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLD-KDLKMMKL 5852
Query: 1286 QEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNEL 1465
Q+Q +A + K+K+E + ER + + E + K ++ L
Sbjct: 5853 QKQVFEEEKNKLEQMKIELEREAD---EIRKIKEETQNERQSLEKMTEELKKEKESFTHL 5909
Query: 1466 AERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAE 1645
AE +K + I S LEE+ + I+ ++ K+
Sbjct: 5910 AEDTKKEQEILDKVKVANESLMADLQKEK--------SNLEEMRENISKQTEDVENKKEN 5961
Query: 1646 VSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEV-----DSAFCSLN 1810
+ D + LQ + Q+ EIEK + ++S + I K V D H++ DS L+
Sbjct: 5962 LRLREDELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLD 6021
Query: 1811 SRFYSLIHKVDNSGETLRAFVKNIQNQV----AVSQEQHIEHQCKEELEGHIADLVLNDF 1978
+ +N E L+ ++ + + E + Q EE+ I D
Sbjct: 6022 REAF------ENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQK--DRDK 6073
Query: 1979 SNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTK 2158
N+++ + RK + V+++ D E+ ++KS+ D ++L+ E+ +++ +
Sbjct: 6074 INNLIEETNRK-DMVLNEKNRDIEK-----KIKSIQSDKDMLEKEK------HDLEKTRS 6121
Query: 2159 GIHYFSQLIQEGKDGEASDVQGKSRALRRHSTG----------QAFREPPKPEDLYTTYS 2308
++ + +++ K+ + +Q + L + + Q + K ++L +
Sbjct: 6122 ELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKT 6181
Query: 2309 EGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQR 2488
E + ++ +EK+++ + A D S L K+Q + +K E + +L +
Sbjct: 6182 EIQNLQQELEKEKEII-MKARSQLDRRQSEL---DKQQT--NMNDIMETMKNERK-QLDK 6234
Query: 2489 KTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYK 2668
EE+ + K+ + E++ + K+++ K + EE + +
Sbjct: 6235 DKEEMEEQKQEMEKERDNMDQSRKSLDEDL------------KMMKLQKQVIEEEKNKLE 6282
Query: 2669 MLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKS-------ADHAQRESHLL- 2824
+K EL+ + D +++IKE+ N + + EK+++ LKK A+ +RE + L
Sbjct: 6283 Q---MKIELEREADD-IRKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTKREKNSLD 6338
Query: 2825 -------KHIADLEAGITDREIMTSVCSDVLTALFVE----MVREKEF---------SLS 2944
+ADL+ ++ E M S + E +RE E S
Sbjct: 6339 EMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQS 6398
Query: 2945 LATKEQETVNQKQMSLRKMLED-KDKLLCL------------VGEENKEHKRQIAI---- 3073
E+ + +++ ++ K +ED + K++ L E KE +Q+
Sbjct: 6399 ETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELER 6458
Query: 3074 ----LEKLKEETENNPGRV------FLQ--SEEREKIEEQKRVLDQALQECEELKNDIQN 3217
+EK+K ET++ RV F++ + ER+++++ K ++++ QE E+ ++D+
Sbjct: 6459 EADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQ 6518
Query: 3218 KHSDIDS-----------LREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDS 3364
+D L EE+ KL + M NL+
Sbjct: 6519 SRKSLDEDLKMMKAQKQVLEEEKNKLEQ----MKIGLEREADEISKIKEETQNERQNLEK 6574
Query: 3365 MQLELRNYNEELKNEIEKKSTDIDL-----------LIKEKEELNERLAYTQKAMEQKEA 3511
M L+ E L EI++K+ +D L KEK L E K +E E
Sbjct: 6575 MANALKEEREYLAEEIKRKNQVLDKIKVANESTLADLQKEKRILEEMRENISKQIEDIEN 6634
Query: 3512 VLVE-KLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKE 3688
+ KL E E K L E + + EK ++ E A + ++ + EL+ K
Sbjct: 6635 EKEKSKLREDELKKLQTEVQKQQSEIDMEK-----TNIESERAAMIREKQNMMTELKKKS 6689
Query: 3689 RDLEVAMTETKFLKEKLLVSDENLKEKDLQ 3778
D+E+ M E KE LL +D NL +KD++
Sbjct: 6690 EDVEMQMKEILTEKE-LLHNDRNLLKKDVE 6718
Score = 115 bits (287), Expect = 2e-22
Identities = 245/1253 (19%), Positives = 499/1253 (39%), Gaps = 71/1253 (5%)
Frame = +2
Query: 275 EVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTK 454
E ED +T+K+ + L+ M++ T + +L + + ED+ N K
Sbjct: 5032 EREDLAEETKKN-----NQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKK 5086
Query: 455 DLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSL 634
+ L E L L + Q+ E ++ +SE + K +EDL HKI L
Sbjct: 5087 ENLRLREDEL--------RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICL 5138
Query: 635 E---ETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMV 805
+ E+L+ E + E + + L+ E + ++ Q Q++ E M
Sbjct: 5139 DRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIKLETQHDRQRV-----EEMAAQ 5193
Query: 806 LEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEE 985
++KD ++ IE ++ L+ RD IE++ + +K ++E E+
Sbjct: 5194 IQKDRD--EINNLIEETNRKDMVLNEKNRD-IEEKIKSIQSDKDMLEK----------EK 5240
Query: 986 HDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYEN 1165
HDL K + E+ +K++ ++ + AEI K LE+ MN N+ T E++E
Sbjct: 5241 HDL-----EKTRSELYKVKEDLEKQKENTLAEIQKEREDLEK--MNENI----TREMHEI 5289
Query: 1166 TFRE------------LGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXX 1309
+E L +I L+ ++ + I S++D SE +K Q
Sbjct: 5290 KHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIM 5349
Query: 1310 XXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISEN---LERISKLQKMNNELAERSK 1480
K ME Q K E+E+ER + ++ L+ K K+ ++ E K
Sbjct: 5350 ETMKNERKQLDKDKEEMEEQ----KQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEK 5405
Query: 1481 SQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHL 1660
N + N +LE++T+++ +E E HL
Sbjct: 5406 --NKLEQMKIELEREADEISKIKEETQNKR--QRLEKMTEELI--------REKESLAHL 5453
Query: 1661 -DTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHK 1837
+ + + +L K E S LQ +S +E++ L
Sbjct: 5454 AEDTKTEKKILDEMKVANESSMADLQREKSILEEM---------------RENISKLKEY 5498
Query: 1838 VDNSGETLRAFVKNIQN-QVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKE 2014
+DN E + ++ Q V ++Q K +E A ++ + N + ++ E
Sbjct: 5499 IDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMI-REKQNMMTELKKKSE 5557
Query: 2015 EAVVHDDEFDAERIALLNELKSLHQDLELLKAEEA-VKSLSNNVGVSTKGIHYFSQLIQE 2191
+ + E E+ L N+ K L +D+E L+ + ++ S + + + + +++
Sbjct: 5558 DVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQ 5617
Query: 2192 GKDG---EASDVQGKSRALRRHS-------TGQAFREPPKPEDLYTTYSEGKIV--EPHP 2335
K +A +++ K + +H Q +E K +L + +V E +
Sbjct: 5618 MKTDLQIQADEIE-KIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNR 5676
Query: 2336 TEEKKLLAILAFETADASDSPLRNWPKEQL-LGHFKQSFAGLKREYELELQRKTEEIYDL 2512
E+K+ +I + + D + N K + L K+ K E+Q++ E++ +
Sbjct: 5677 DIEEKIKSIQSDK--DMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKM 5734
Query: 2513 KRLLLNEKNGL---HAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQ---RYKML 2674
+ E + + EI +++ +E +++ + Q R L
Sbjct: 5735 NENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQFDLRQSEL 5794
Query: 2675 CVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGI 2854
+ + ++++ E K+ D + + + E+ + K+ D Q L K DL+
Sbjct: 5795 DKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDK---DLKMMK 5851
Query: 2855 TDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLV 3034
+++ + L + +E+ RE + + ++ET N++Q SL KM E+ K
Sbjct: 5852 LQKQVFEEE-KNKLEQMKIELEREAD---EIRKIKEETQNERQ-SLEKMTEELKKEKESF 5906
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQ 3214
++ K++ IL+K+K E+ + +E+ +EE + + + ++ E K +++
Sbjct: 5907 THLAEDTKKEQEILDKVKVANESLMADL---QKEKSNLEEMRENISKQTEDVENKKENLR 5963
Query: 3215 NKHSDIDSLREEQEKLNKQLRC--MXXXXXXXXXXXXXXXXXXXXISSNLDSMQLEL--- 3379
+ ++ L+ E K +++ + IS + DS L+L
Sbjct: 5964 LREDELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDRE 6023
Query: 3380 -----RNYNEELKNEIEKKSTDIDLLIKE----KEELNERLAYTQKAME----------Q 3502
R +++K E+E+++ +I+ + E ++ + E A QK + +
Sbjct: 6024 AFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNR 6083
Query: 3503 KEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQS 3682
K+ VL EK + E+KI ++S + ++ + L + DL+KQ + ++Q
Sbjct: 6084 KDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQK 6143
Query: 3683 KERDLEV-------AMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQYQ 3820
+ DLE M E K +E++ N K+ +L EI N +++ +
Sbjct: 6144 EREDLEKMNENITREMHEIKHQEEQM-----NQKQDELDQLKTEIQNLQQELE 6191
Score = 114 bits (285), Expect = 3e-22
Identities = 238/1256 (18%), Positives = 500/1256 (39%), Gaps = 82/1256 (6%)
Frame = +2
Query: 287 GGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLD 466
GGL T + LE+M+ + ++M L ++ + L +DI K+ D
Sbjct: 8708 GGLKTEIENTKRDKSNLEKMKAELEEKQQEEESMREILQKEKEELEQLKKDINREKE--D 8765
Query: 467 TVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETL 646
S V + + + + G Q+ +KE L E + +E LN + L +TL
Sbjct: 8766 IEISRELVESEIYEGEVKGFTDVQK--YKEELQIVTEELLTKKRNLEQLNSDVQHLMQTL 8823
Query: 647 QYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQK-LASRDNEMMHMVLEKDNI 823
EEV + + +E + + + + +++++ ++ E+ + EMM + LE N+
Sbjct: 8824 ---EEVDIQYIKKKAELEHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINM 8880
Query: 824 -ILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLR 1000
IL + +E + +N RR++ E + + E+++Q E + Q L E D +
Sbjct: 8881 EILQKREDMEKEKEN------LRREKQETELFRGELQRQRDEV--ESSRQALIMEKDQFK 8932
Query: 1001 LESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFREL 1180
L+ ++E+ + ++ H + + + ++ L ES+ N ++
Sbjct: 8933 LKIDHQRNEMSAAFEKEHKRLENMENDLENQRAKLAESL---------------NDAAKM 8977
Query: 1181 GDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASM 1360
++ Q++N++ + ++ + + +E K++++ L+
Sbjct: 8978 EQKLQQMKNELNKEKEQVEEMKQMV---KTERVKIEQEKEEMRKQTQEIEDGHEKLQKKT 9034
Query: 1361 EMQCSKLKD-ELEEERGK-ISENLE-RISKLQKMNNELAERSKSQNSIXXXXXXXXXXXX 1531
E+ L+D E +R K +S L+ + ++K N E+ + +S + +
Sbjct: 9035 EIADKLLQDANSESDRLKDLSMKLQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLK 9094
Query: 1532 XXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEI 1711
+ + E + + ++ ++ ++E + K +I
Sbjct: 9095 NDRDAYEKDMTHLELKREELVRETEDLERKILQQREQDEMA---------------KRDI 9139
Query: 1712 EKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQ 1891
E + L+ + I K N+ E+++ +S K+ L++ ++N+
Sbjct: 9140 ENQTEALEVMKVDILKKRNEFAKEMENV--------HSERQKLLLLQGALQSQESELENR 9191
Query: 1892 VAVSQEQHIEH------QCKEELEGHIADLVL---NDFSNDILSWSRRKEEAVVHDDEFD 2044
V + +++H++ +C+++L +++ V N++ I R KE+ + ++ +
Sbjct: 9192 VFMEEQKHLKQAKAETEECRKQL-AEMSETVTTEQNEYRKLIEELQREKEQLEISKNQIE 9250
Query: 2045 AERIALLNELKSLHQDLELLKAEEA----VKSLSNNVGVSTKGIHYFSQLIQEGKDGEAS 2212
E+ L N +L + LE L+ E+A K+ + +K I + +E +
Sbjct: 9251 QEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWV 9310
Query: 2213 DVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAIL--AFETADA 2386
+++G+ + + E + +E H E KK+ + L + E ++
Sbjct: 9311 EIEGEKKRMEE---------------------ETRRLEMHREEIKKVDSELQKSRENIES 9349
Query: 2387 SDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDL---KRLLLNEKNGLHAXX 2557
+ + N +E L K K E E E QR + DL K + +++
Sbjct: 9350 REEKINNKMEELL--QMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDII 9407
Query: 2558 XXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKM-LCVLKEELQSKIDSLLKEIKE 2734
+ K K L E L V++++ + K+E++ L KE +E
Sbjct: 9408 DIKIQEKEREIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQE 9467
Query: 2735 KDSNSKVLAEKLSD----------------ALKKSADHAQRESHLLKHIADLE-AGITDR 2863
K L +++ D ALK + ++E+ ++K LE + I +
Sbjct: 9468 LKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEM 9527
Query: 2864 EIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQM---SLRKMLEDKDKLLCLV 3034
++ + E +EKE SL + ET QKQM S KM+E+K+++ L
Sbjct: 9528 QLKIFKQQRLNDQTREENKKEKE---SLEQQRFETEQQKQMLEISTTKMMEEKNEMADLS 9584
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVF-LQSE---EREKIEEQKRVLDQALQECEELK 3202
E K LEK+ +T V +Q+E + + IE+Q +++ EE +
Sbjct: 9585 RELQKAKDE----LEKIAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEKE 9640
Query: 3203 NDIQNKHSDI--------------DSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXX 3340
IQ K +I +++ EE K L M
Sbjct: 9641 LSIQRKEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQKNNKDFELLE 9700
Query: 3341 XISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEA--- 3511
I S L++ + +L+ + E+ K+ +E + +++ KEKE L + Q EQ E
Sbjct: 9701 KIRSELENEKYDLQIWTEQQKHLVEVQLQELE---KEKERLEKMEIELQSKREQTEKEKA 9757
Query: 3512 --------------VLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLK- 3646
V+ +K + + LE+ ++ +E+ EK + L EE ++
Sbjct: 9758 DLNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQI 9817
Query: 3647 --KQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSE 3808
+ EE++ ++ LE++ + K +KE+ + E + K + +I N+E
Sbjct: 9818 EAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEE-QIQNNE 9872
Score = 114 bits (284), Expect = 4e-22
Identities = 231/1252 (18%), Positives = 504/1252 (40%), Gaps = 81/1252 (6%)
Frame = +2
Query: 302 RKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESG 481
R L+ + +E L++ + + D T+KN L +D + +++ +D +D
Sbjct: 5328 RSQLDLRQSE-LDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKS 5386
Query: 482 LYVSNVVSDAVLNGVVSAQE----EEFKEALAAKDSENFLLNKKIEDLNHKIWSL-EETL 646
L L + +E E+ K L + E + ++ ++ ++ + EE +
Sbjct: 5387 LDEDQ--KKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELI 5444
Query: 647 QYKEEVILSSHETISERDRL----------LKDFIHEKDLMQQRAQETEQKLASRDNEMM 796
+ KE + + +T +E+ L + D EK ++++ + + DNE
Sbjct: 5445 REKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENISKLKEYIDNEKE 5504
Query: 797 HMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIED---------QNIKEEIEKQIVET 949
L +D + K+++ + Q QS + IE QN+ E++K+ +
Sbjct: 5505 KSKLREDEL-----KKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKKSEDV 5559
Query: 950 IYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEM-SKQAEISKLSHTLEESIMNS 1126
Q++E+ E +LL + ++++L+ + E SK+ ++ + + E+ M
Sbjct: 5560 --EIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQ 5617
Query: 1127 NLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXX 1306
L + D+I +++ + ++ +A++I + N L E+
Sbjct: 5618 MKTDL----------QIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRK 5667
Query: 1307 XXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQK-----MNNELAE 1471
S++ KD LE+ER + + + K+++ N LAE
Sbjct: 5668 DMVLNEKNRDIEEKIKSIQSD----KDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAE 5723
Query: 1472 RSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVS 1651
K + + E++ + I I +E +++
Sbjct: 5724 IQKEREDV------------------------------EKMNENITREMHEIKHQEEQMN 5753
Query: 1652 GHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLI 1831
D + L+T + N + E+EK ++++ S + + E+D ++N ++
Sbjct: 5754 QKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQFDLRQS----ELDKQQTNMND----IM 5805
Query: 1832 HKVDNSGETLRAFVKNIQNQVA-VSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRR 2008
+ N + L + ++ Q + +E+H Q ++ L+ DL + + +
Sbjct: 5806 ETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLD---KDLKMMKLQKQVFEEEKN 5862
Query: 2009 KEEAVVHDDEFDAERIALL-----NELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYF 2173
K E + + E +A+ I + NE +SL + E LK E K ++ TK
Sbjct: 5863 KLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKE---KESFTHLAEDTKKEQEI 5919
Query: 2174 SQLIQEGKDGEASDVQGKSRAL---RRHSTGQAFREPPKPEDLYTT-----------YSE 2311
++ + +D+Q + L R + + Q K E+L Y +
Sbjct: 5920 LDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQ 5979
Query: 2312 GKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLK---REYELEL 2482
+ +E + A + D + + L +++F + ++ + EL
Sbjct: 5980 QREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTEL 6039
Query: 2483 QRKTEEIYDLKRLLLNEKNGLH--AXXXXXXXXXXXXVAEITGKFEKVLQENKL---LPV 2647
+R+ +EI +K +++ + + E T + + VL E +
Sbjct: 6040 EREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKI 6099
Query: 2648 EEVQRYK-MLCVLKEELQSKIDSLLK---EIKEKDSNSKVLAEKLSDALKKSADHAQRES 2815
+ +Q K ML K +L+ L K +++++ N+ +K + L+K ++ RE
Sbjct: 6100 KSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREM 6159
Query: 2816 HLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSL---SLATKEQETVNQKQM 2986
H +KH E + ++ + L E+ +EKE + S + Q ++++Q
Sbjct: 6160 HEIKH---QEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQT 6216
Query: 2987 SLRKMLE---------DKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQS--- 3130
++ ++E DKDK + E+ +E +++ +++ ++ + + + LQ
Sbjct: 6217 NMNDIMETMKNERKQLDKDKEE--MEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVI 6274
Query: 3131 -EEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXX 3307
EE+ K+E+ K L++ + ++K + QNK ++ + EE +K K + +
Sbjct: 6275 EEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTKREK 6334
Query: 3308 XXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQ 3487
S++ +Q E N EE+K I K++ DI+ KEK+++ R +
Sbjct: 6335 NSLDEMKVAN---ESSMADLQKEKSNL-EEMKENISKQTEDIE---KEKDKIRLR----E 6383
Query: 3488 KAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLK---KQFL 3658
+EQ +A + ++ E E + +E ++A + E + + SL + LK + F
Sbjct: 6384 DELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFE 6443
Query: 3659 SATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQ 3814
+ EEL+ + +LE E + K KL E + +++ E N+E++
Sbjct: 6444 NEKEELKQMKTELEREADEIE--KIKLETQHERQRVEEMTADFMETMNNERK 6493
Score = 111 bits (277), Expect = 3e-21
Identities = 233/1162 (20%), Positives = 476/1162 (40%), Gaps = 76/1162 (6%)
Frame = +2
Query: 524 VVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDR 703
+V+ +EE K+ ++S N + KK +L H+ L + Q E++I S + + +R
Sbjct: 13192 LVNMEEEIKKQRRVLEESMNEMTKKK-SELQHERSELYKQKQQLEDMIASESKRDVDTER 13250
Query: 704 LLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDC 883
+D E+ L ++R + + K +L++ + + ++I + ++ + +
Sbjct: 13251 SRQDKEDEQILKREREEIADMK---------DQLLKEKEDVETTKERINREKEHIEKMQS 13301
Query: 884 FRRDEIEDQNIKEE------IEKQIVETIYVTQIQELGEEHD---LLRLESAKYQDEIQS 1036
D+ E+ +++ + E Q+ +Q+L +E + L ++ K +++
Sbjct: 13302 QLNDQKEEMDLENQKLLYMKTEIQVKTNALEKMMQDLQKERENVNALVIQHQKEREQRDI 13361
Query: 1037 LKDECHAKEMSKQAEISKLSHTLE----------ESIMNSNLESLFTAEIYENTFRELGD 1186
L +E KE +AEI + +E I N E +E EN ++
Sbjct: 13362 LIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTRSEELENLIKKQQK 13421
Query: 1187 QISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEM 1366
+ N+M + ++ + + ++ S+E E+ LK +E
Sbjct: 13422 EFETKENEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILER 13481
Query: 1367 QCSKLKDELEEERGKISENLERISKLQK-MNNELAERSKSQNSIXXXXXXXXXXXXXXXX 1543
+ K EL +E+ ++ + + ++K M +E+ +N +
Sbjct: 13482 E----KSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELE--------------- 13522
Query: 1544 XXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQ 1723
+ + + ++++ IDK + E+ ++I + L K E E +
Sbjct: 13523 -----------DEKKSMLSRLSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKR 13571
Query: 1724 KVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVS 1903
L ++ IEK+ D L + SL L K + E +R K +Q +S
Sbjct: 13572 TQL---DNTIEKMNMDKL-SIQREKDSLEEIKADLQRKAEKLDEEMR---KAVQITSQIS 13624
Query: 1904 QEQHI---EHQCKEELEGHIADL-----------VLNDFSNDILSWSRRKEEAVVHDDEF 2041
Q+ I + + +EEL AD+ L +IL S+ + + + D E
Sbjct: 13625 QDAKILDDDREKEEELRSMRADIERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEK 13684
Query: 2042 DAERIAL-LNELKSLHQDLE-----LLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDG 2203
+R L L EL+ LE + K ++AV SL N V + + + E +
Sbjct: 13685 QRKRNDLTLQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRK- 13743
Query: 2204 EASDVQGKSRALRRHSTGQAFREPPKPEDLYTT-----YSEGKIVEPHPTEEKKLLA--I 2362
E D++ +R++ST + +E D++ ++ + ++ EE++ L I
Sbjct: 13744 EMDDLR-MQLEMRQNSTNKQQQE----VDVFIVENMKMRNDLESMKTLLDEERRQLQDNI 13798
Query: 2363 LAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNG 2542
FE P + +Q ++ +K E E ++++ EEI L + ++ K
Sbjct: 13799 KTFEDQKNVLHPSKTDAVQQ-TDELEKFTTDIKTEKE-HVEKEREEIDVLNKEIIKSKEE 13856
Query: 2543 LHAXXXXXXXXXXXXVAEITGKFEKV-----LQENKLLPVEE----VQRYKMLCVLKEEL 2695
L + EI GK ++ L+ + L ++ VQ K + + E
Sbjct: 13857 LQSLNLEIEMFK----QEIAGKRAQIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEK 13912
Query: 2696 QSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLL-KHIADLEAGITDREIM 2872
+++++ + K+K+ E+L + ++ + +L K ++E +IM
Sbjct: 13913 KTEVELQMNLQKQKNE-----LEELRNTIEAEKHQVENRKIMLDKQQKEVE------DIM 13961
Query: 2873 TSVCS--DVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLE----DKDKLLCLV 3034
T + S DVL +EK L+ E V ++Q L ++LE D + ++
Sbjct: 13962 TVIKSERDVLE-------KEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKII 14014
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLD----QALQECEELK 3202
E + +R+ A L++LKEE E R LQ +++ I+++K L+ + +E LK
Sbjct: 14015 ESEKQSIERERAELKRLKEEVEVQHERTLLQ-QDKNMIQKEKEHLEGEKARTTEEIHNLK 14073
Query: 3203 NDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLE-- 3376
+I+ K S++D L +E E ++ + + +++E
Sbjct: 14074 EEIKRKSSELDMLNKEIEAKRQE----------------------EELHGLPEEIEIEDH 14111
Query: 3377 LRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQ-------KAMEQKEAVLVEKLFE 3535
L+ ++ L+ EI KK D K + + R A TQ K E+++ L E +
Sbjct: 14112 LKKEDDVLREEIIKKQ-QTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRALEETVAT 14170
Query: 3536 GEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTE 3715
++ ++++ + T E ++ RD LN+ +E A +K ++L+ + D++ M E
Sbjct: 14171 TAKQPIVIKLEDTLTSE-VQEMRDHLNNEIKELARMKTIMKMEKDQLKQAKSDIQTQMEE 14229
Query: 3716 TKFLKEKLLVSDENLKEKDLQL 3781
+ E+ + +EK LQL
Sbjct: 14230 FERNMEEAMEEKSRNEEKLLQL 14251
Score = 108 bits (270), Expect = 2e-20
Identities = 257/1319 (19%), Positives = 522/1319 (39%), Gaps = 140/1319 (10%)
Frame = +2
Query: 230 VMDGQGCDISVTSFIEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNF----- 394
+ D Q I S ++ E+ + + K ETL+ ME H +K+++
Sbjct: 10703 IADEQDLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRL 10762
Query: 395 --DLGQDNPGVPGLLEDIRNTKDLLDTVESGL-----YVSNVVSDAVLNGVVSAQ-EEEF 550
DL + + V +D+ N +DLL+ + + + + + VS Q E++
Sbjct: 10763 KEDLEKMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQQRIDE--FDAQVSKQKEQDL 10820
Query: 551 KEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEK 730
+ K+ L K + K + E ++ ++E E E R++ + K
Sbjct: 10821 PKEKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVE-TERK 10879
Query: 731 DLMQQRAQ--------ETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCF 886
+L Q +++ + EQK + N+ M M+ ++ + + +I Q Q +
Sbjct: 10880 ELYQIKSELERVRSEIDHEQK---KLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSE 10936
Query: 887 RRDEIEDQNI-KEEIEK--QIVETIYVT-----------------QIQELGEEHDLLRLE 1006
++I+ N+ K +IEK +IVE + V + Q++ +E +LL
Sbjct: 10937 LDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQN 10996
Query: 1007 SAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGD 1186
AK Q+E + +K EI K TL E ++ E I E T R D
Sbjct: 10997 KAKLQNENERIK--------KVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKED 11048
Query: 1187 QISQLRNDMYSKNSYI----DSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKA 1354
+ ++ D+ + ++ D L + ++ E +LQ++ A
Sbjct: 11049 -LEKMSTDINEQKLHLKNQRDLLEQEREEINHEMTQLQQRIDE--------------FDA 11093
Query: 1355 SMEMQCSKL-KDELEEERGKISENLERI------SKLQKMNNELAERSKSQNSIXXXXXX 1513
+ Q L K E+EEER + E RI ++LQ++ E E + + +
Sbjct: 11094 QVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRV------ 11147
Query: 1514 XXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLS 1693
+V M +L ++ ++ S ID ++ +++ I + L
Sbjct: 11148 --------------IVEME-REELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLE 11192
Query: 1694 NQKFEIEKSQKVLQSFESHIEKLVNDS---LHEVDSAFCSLNSRFYSLIHKVDNSGETLR 1864
K EI ++ ++ S ++ + + H+++++ L+ KV+ + +R
Sbjct: 11193 KMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENS----KEIVQKLMVKVEEQRKDIR 11248
Query: 1865 AFVKNIQ-NQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEF 2041
+ + + ++ EQ + Q K +L+ N+ ++ ++++E + E
Sbjct: 11249 LQKEELDIERQKIADEQGLVVQNKAKLQNE------NERIKEMDEEIKKEKETL---KEM 11299
Query: 2042 DAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQ 2221
+A E++S+ ++ + K E+ ++ +S +V + + L+++ E ++
Sbjct: 11300 EAHLRKEKEEMRSVIEETQRRKKED-LEKMSTDVNKQNQDLMNQRDLLKQ----EREEIN 11354
Query: 2222 GK-SRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSP 2398
K ++ +R A K EDL + K+ E + E+ + I+ +T +
Sbjct: 11355 HKWTQLQQRIDEFDAQVSKQKEEDL---TKQKKMEEERKSLEETKIKIIEMKTKTEPEKI 11411
Query: 2399 LRNWPKEQ------LLGHFKQSFAGLKREYE---LELQRKTEEIYDLKRLLLNEKNGLHA 2551
+ KE+ + K+ +K + E E+ + +++ D K+++ EK L
Sbjct: 11412 KKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEK 11471
Query: 2552 XXXXXXXXXXXXVAEITGKFEKVLQEN-------------KLLPVEEVQRYKMLCVLKEE 2692
E + K+ Q + + L VE ++ K + + KEE
Sbjct: 11472 MKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEE 11531
Query: 2693 L-----------------QSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHL 2821
L ++K+ + + IKE D K K + LK+ H ++E
Sbjct: 11532 LDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHLRKEKEE 11587
Query: 2822 LKHI---------ADLEAGITD-----------REIMTSVCSDVLTALFVEMVREKEFSL 2941
++ + DLE TD R+++ ++ R EF
Sbjct: 11588 MRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDA 11647
Query: 2942 SLA-TKEQETVNQKQM-SLRKMLED-KDKLLCLVGEENKEHKRQIAILEKLKEETENNPG 3112
++ KE++ QK+M RK LE+ K K++ + + E ++ EK KEE E
Sbjct: 11648 QVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKK----EKEKEEEEVMRA 11703
Query: 3113 RVFLQSEE-----------REKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEK 3259
+V ++ EE R +I+ +++ L+ + E+ K D++ S+I R++ E+
Sbjct: 11704 KVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEE 11763
Query: 3260 LNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDL 3439
+L + ++ + E++ EEL E +K + + DL
Sbjct: 11764 ERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDL 11823
Query: 3440 LIKEKEEL---NERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDL 3610
LI+ K EL NER+ + ++++ L E E++ ++S TR Q E +
Sbjct: 11824 LIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSITEETRRQKEDLEKM 11883
Query: 3611 LNSLTEEHADLKKQ---FLSATEELQSKERDLEVAMTE----TKFLKEKLLVSDENLKE 3766
+ E+ DL+ Q EE+ K + L+ + E KE+ L ++ +KE
Sbjct: 11884 STHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKE 11942
Score = 107 bits (266), Expect = 5e-20
Identities = 223/1154 (19%), Positives = 456/1154 (39%), Gaps = 85/1154 (7%)
Frame = +2
Query: 596 KKIEDLNHKIWSLEETLQYKEEVILSSHETIS-ERDRLLKDFIHEKDLMQQ-RAQETEQK 769
K IE +I E L+ ++ + S +T+ ER L K KDL +Q +Q + +
Sbjct: 2854 KDIETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHE 2913
Query: 770 LASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIV-E 946
+ + + +LE+ + LS K+ +L+ + DCF +++ D +++EE+++Q E
Sbjct: 2914 IQLAEIQKEREILEQLKLTLSKQKE-DLEKER----DCFEKEKA-DISLREELQEQSERE 2967
Query: 947 TIYVTQIQELGEEHDLLR--------LESAKYQDEI---QSLKDECHAKEMSKQAEISKL 1093
I T+++ E +L + LE+ + Q +I + K E E+ K+AE ++
Sbjct: 2968 GIGKTRVRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEK 3027
Query: 1094 SHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSE 1273
E +N E + + N +++ ++R++ + L S D L E
Sbjct: 3028 QRRDIEKDRRNNEEMVIKLQ---NEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKE 3084
Query: 1274 -------------CNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERG-- 1408
K E + +++ SK K++LE+ER
Sbjct: 3085 RFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCF 3144
Query: 1409 -------KISENLERISKLQKMNN-------ELAERSKSQNSIXXXXXXXXXXXXXXXXX 1546
+SE+L+ S+ + ++N E+ E K++ ++
Sbjct: 3145 EKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDE 3204
Query: 1547 XXXVVNM-------AFGSKLEELTDQINI--FNSVIDKKEAEVSGHLDTISSLQTVLSNQ 1699
+ + A +KLE ++ N+ + + K V + + Q VL N
Sbjct: 3205 RDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKKDRENVESLAEELGRKQVVLENM 3264
Query: 1700 KFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKN 1879
+ E E +K +S + E+++ + V + K D + L KN
Sbjct: 3265 QIETEMQRKANESNKQMQERVLIELKKTVTDIAGA----------KEDLENQLLEEREKN 3314
Query: 1880 IQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVH--DDEFDAER 2053
Q + E+ + + K+ + D+V + + +A+++ DE +A R
Sbjct: 3315 KVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQLRLREVELEQLQALIYRQQDEIEANR 3374
Query: 2054 IALLNELKSLH-QDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKS 2230
A++NE L Q E+ + + V + + Y S KD + +
Sbjct: 3375 KAIINEKYRLEGQKTEIDRLQREVNQM----------MEYAS------KDRANLEKEKSE 3418
Query: 2231 RALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNW 2410
++H D+ G I EE+ + + D + L
Sbjct: 3419 MIAQKHQM-----------DIELNKERGLI------EERTQMLNTYEKEMDQKRTALEVE 3461
Query: 2411 PKEQLLGHFKQSFAGLK---REYELELQRKTEEIYDLKRLLLNEKNGLH--AXXXXXXXX 2575
KE L + KQ+ K ++ ++ELQR+ ++I LK NE+ L A
Sbjct: 3462 MKE--LKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKD 3519
Query: 2576 XXXXVAEITGKFE---KVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSN 2746
+AE T + + KVL E+ L +++ K L+ +S+ K+ + DS
Sbjct: 3520 DLAHLAEDTKRKDDEMKVLHESALADIQKE---------KCNLEQMRESMFKQNEMIDSE 3570
Query: 2747 SK--VLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMV 2920
K +L E ++ + Q E K I + +R MT D++T L +
Sbjct: 3571 KKKMILREDKLQQMQAEINRQQTEMDTKKSIIE-----NERAAMTKKNQDLMTEL-TKQS 3624
Query: 2921 REKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETE 3100
+ E + E+E + + L+K +E+ + L ++ ++ E LK++ E
Sbjct: 3625 EDVEIQMKEVLTEKELLESDRKLLKKDVENLQQKLLIIESDS----------ESLKQDRE 3674
Query: 3101 NNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRC 3280
L E+E +++ K L +E E++K + Q++ ++ + + +K + L+
Sbjct: 3675 -------LLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQK 3727
Query: 3281 MXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEEL-----------------KNE 3409
M LD ++ E++N +EL ++E
Sbjct: 3728 MNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLKQSE 3787
Query: 3410 IEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQ 3589
++K+ T+++ +I+ + ++L ++ ME+++ + ++ + +Q L+ + Q
Sbjct: 3788 LDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQ 3847
Query: 3590 TEKYRDLLNSLTEEHADLKK---QFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENL 3760
+ + + N L + +L++ + EE+Q++ + LE E K KE E+
Sbjct: 3848 KQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESFTHLAEDT 3907
Query: 3761 KEKDLQLRAFEIAN 3802
K++ L ++AN
Sbjct: 3908 KKEQEILDEIKVAN 3921
Score = 107 bits (266), Expect = 5e-20
Identities = 244/1167 (20%), Positives = 478/1167 (40%), Gaps = 76/1167 (6%)
Frame = +2
Query: 536 QEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKD 715
QE + +A K E ++ +KIE E +Q +++ + S E + ++ + +K
Sbjct: 7764 QELDLIQAKVVKQKEE-MVKQKIES--------EREIQQEKKKLQRSEEELEDKMQKIKR 7814
Query: 716 FIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNI------ILSLHKQIELQSQNTQSL 877
+ E L+Q ET+ K DN+M + ++D + + S K++E+ +
Sbjct: 7815 EMIELKLLQD---ETDGKRKDVDNKMRQVARKRDELEKMKADVESASKKLEVDRVMLNT- 7870
Query: 878 DCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDL------LRLESAKYQDEIQSL 1039
RDE+E + + + +++ + +LGE+ + L E+ K S
Sbjct: 7871 ---ERDELERIKTESQRATEHMQSHAEERAGDLGEKEPVNTRIQRLIQEAEKASKMAWST 7927
Query: 1040 KDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTA-EIYENTFRELGDQISQLRNDMY 1216
K H EM Q E+S ++E M++N++ + E T R + D++ R +
Sbjct: 7928 K---HEPEMRMQREVSVEEESVERQDMSANMQRMILEIEHARETLRGMKDEVQAARKE-- 7982
Query: 1217 SKNSYIDSLASRIDFLSSECN--KLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDE 1390
S ++++ +++FL+ + N K EQ S +M S+ +++
Sbjct: 7983 --RSELENM--KLEFLTMKKNMEKTYEQQNDEIQKEKQQIE-------SSKMLLSRERND 8031
Query: 1391 LEEERGKISENLERISKLQKMN----NELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXV 1558
LE+ R + E ++I L K NEL ER K+ +
Sbjct: 8032 LEQNRADL-ERQKQIMALDKQKLLAENELLEREKAD--VIKIIENLESLREEATRERATE 8088
Query: 1559 VNMAFGSKLEELTDQINIFNSVIDKKEA------EVSGHLDTISSLQTVLSNQKFEIEKS 1720
A EEL ++ S+ D +EA E+ +D + L+ L Q+ E++K+
Sbjct: 8089 TAQATRRDSEELMQKMEAL-SMEDFQEASKNQMVELKRQIDKLIELKADLLQQQTELKKT 8147
Query: 1721 QKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAV 1900
+ L+ +EK +R L H+ D +T + IQ Q
Sbjct: 8148 KADLKQQMDDLEK-----------------TRSEILKHEKDTDSKTRELELIEIQRQ--- 8187
Query: 1901 SQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALL---NE 2071
K++LE I L L ++L + E V+ + D + ++ +E
Sbjct: 8188 ----------KDDLETRIQKLTLEKRDLEVL-----RSEIVLEKKDLDQKMKQVIRKRDE 8232
Query: 2072 LKSLHQDL-----ELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQ-----EGKDGEASDVQ 2221
++ + D+ E+ + + ++ L NNV + H F L++ E ++ A+D++
Sbjct: 8233 MEKIRSDIANATEEINRERQELEILRNNVQSAR---HDFELLLERTANLEDEESAATDIE 8289
Query: 2222 G------KSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETAD 2383
K R + R+ G+ R K + VE +EK++
Sbjct: 8290 RLVLEVVKIREMVRNLKGEMERRMEKSK-----------VE---IDEKEIFK-------- 8327
Query: 2384 ASDSPLRNWPKEQLLGHFKQSFAGL----------KREYE---LELQRKTEEIYDLKRLL 2524
S ++ + ++ +G +++ GL KRE E EL K +E ++ +L
Sbjct: 8328 ---SEIQRFIQD--IGQIRENLGGLGEEIEKTRRDKRELEKMRAELAEKQQEQESMREML 8382
Query: 2525 LNEKNGLHAXXXXXXXXXXXXVAEITGKF-EKVLQENKLLPVEEVQRYKMLCVLKEELQS 2701
E+ L EI + E V+ + ++ ++Q+YK EELQS
Sbjct: 8383 HKEREELEQLKDEINREKED--VEIRRELVEAVIDKEEMKEFTDIQKYK------EELQS 8434
Query: 2702 KIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSV 2881
+ LL + ++ D + + + + + H ++ + L +L+ G E +
Sbjct: 8435 VTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFELKKG----EQLLEK 8490
Query: 2882 CSDVL--TALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEH 3055
D L VE ++ K+ SL E +N M + + ED DK + +E +E
Sbjct: 8491 QKDELKENGWIVEEIKNKKDSL-------EKIN---MEILRKNEDMDKEKGKLRQEKQEM 8540
Query: 3056 KRQIAILEKLKEETENNPGRVFLQSEE----REKIEEQKRVLDQALQ-------ECEELK 3202
+ L++ +E+ E + ++ + E R +I +K+ LDQ ++ E E+++
Sbjct: 8541 DLFRSELQRQREDLETSIQKLTHEKREMEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIR 8600
Query: 3203 NDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELR 3382
DI N +ID R+E E L ++ S+ D +L R
Sbjct: 8601 FDIANARVEIDGERQELEILRDNVQ-----------------------SARQDFERLVER 8637
Query: 3383 NYNEELKNEIEKKSTDIDLLIKEKEELNERL----AYTQKAMEQKEAVLVEK-LFEGEQK 3547
N E++ E +TDI+ L+ E ++ E + ++ ME+ + + EK +F+ E +
Sbjct: 8638 TANLEVE---ESAATDIERLVLEVVKIREMVRNLKGEMERRMEESKVEIDEKEIFKSEIQ 8694
Query: 3548 ILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFL 3727
L+ + Q RE + + + + ++L+K E+ Q +E E+ E + L
Sbjct: 8695 RLIQDIGQ--IRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQEEESMREILQKEKEEL 8752
Query: 3728 KEKLLVSDENLKEKDLQLRAFEIANSE 3808
++ L D N +++D+++ + E+ SE
Sbjct: 8753 EQ--LKKDINREKEDIEI-SRELVESE 8776
Score = 106 bits (265), Expect = 7e-20
Identities = 223/1183 (18%), Positives = 477/1183 (40%), Gaps = 92/1183 (7%)
Frame = +2
Query: 536 QEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKD 715
+EE + + K E + ++E + +I ++ L +++I E + +++ +
Sbjct: 11419 EEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDL---EKMKSE 11475
Query: 716 FIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNT----QSLDC 883
+ ++ M++ E + K+ D E H + I+ L ++E Q ++ + LD
Sbjct: 11476 IMKQRQQMEEERSELDNKIKQTDLER-HDIENSKEIVQKLMVEVEEQRKDIRLQKEELDI 11534
Query: 884 FRRDEIEDQNIKEEIEKQIV-ETIYVTQI-QELGEEHDLLRLESAKYQDEIQSLKDECHA 1057
R+ ++Q + + + ++ E + ++ +E+ +E + L+ A + E + ++
Sbjct: 11535 ERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEE 11594
Query: 1058 KEMSKQAEISKLSHTLEESIMN-SNLESLFTAEIYENTFR---------ELGDQISQLRN 1207
+ ++ ++ K+S + + + N L E E + E Q+S+ +
Sbjct: 11595 TQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKE 11654
Query: 1208 DMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEM------- 1366
+ +K ++ ++ + +++ + ++A +EM
Sbjct: 11655 EDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQ 11714
Query: 1367 ---QCSKLKDELEEERGKISENLERISK----LQKMNNELA--------ERSKSQNSIXX 1501
Q +++ E++ E+ K++++ + I + L+KM +E+ ERS+ +N I
Sbjct: 11715 IKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQ 11774
Query: 1502 XXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQ 1681
+V ++EE +I +D + +++ D + +
Sbjct: 11775 TYIEKCDIENSKEIVQKLMV------EVEEQKHEIQFQKEELDIERQKIADEQDLLIQNK 11828
Query: 1682 TVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETL 1861
+ L N+ I+ +V+ K ++L E+++ S+ + E L
Sbjct: 11829 SELQNENERIKNINEVI--------KKERETLKEMEAYLEKEKEEMKSITEETRRQKEDL 11880
Query: 1862 RAFVKNI--QNQVAVSQEQHIEHQCKEELEGHIADLV--LNDFSNDILSWSRRKEEAVVH 2029
+I Q Q SQ +E + +EE+ L +++F + S++KEE +
Sbjct: 11881 EKMSTHINEQKQDLRSQRDLLEQE-REEINHKWKQLQQRIDEFDAQV---SKQKEEDLPK 11936
Query: 2030 DDEFDAERIAL------LNELKSLHQDLELLKA---EEAVKSLSNNVGVSTKGIHYF-SQ 2179
+ E +R +L + E+K+ + E+ K EE + + V + K I SQ
Sbjct: 11937 EKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQ 11996
Query: 2180 L--IQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKL 2353
L ++ D E + + + + EDL SE EE+
Sbjct: 11997 LERVRSEMDHEQKKLNDDKKMIEQEK-----------EDLEKMKSEIMKQRQQMEEERSE 12045
Query: 2354 LAILAFETADASDSPLRNWPK--EQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLL 2527
L +T D + N + E+L+ + K+++E++ Q+ E D++R +
Sbjct: 12046 LDKKIKQT-DLEKHDIENSKEIVEKLMVEVE------KQKHEIQFQK---EELDIERQKI 12095
Query: 2528 NEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKI 2707
++ L + E+ E++ +E + L EV K KEE++S I
Sbjct: 12096 ADEQDLLIQNKIEQQNENERIKEMD---EEIKKERETLKEMEVNLQKE----KEEIESVI 12148
Query: 2708 DSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCS 2887
+ + ++ + S + E+ D + + Q + + L+ I + E S
Sbjct: 12149 EETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFE----TTS 12204
Query: 2888 DVLTALFVEMVREKEFSLSLATKEQETV----NQKQMSLRKMLEDKDKLLCLVGEENKEH 3055
++L +E E + L A KE E++ N+K+ L ++ D+ ++NK
Sbjct: 12205 NILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTELEEIEVDQS-------QQNKNV 12257
Query: 3056 KRQIAILEKLKEETENNPGRVFLQSEERE--------KIEEQKRVLDQALQECEELKNDI 3211
+ +LEK +++TE + Q+++ E K E KR LD+ + E+ N+I
Sbjct: 12258 ETMKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEI 12317
Query: 3212 QNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYN 3391
+ D++ +E+++ + K + LD +Q E++N
Sbjct: 12318 LRQRDDLE--KEKEDMMKKW--------------------------NELDGLQKEIQNQK 12349
Query: 3392 ---EELKNEIEKKSTDIDLLIKEKEELNERLAYT--------------QKAMEQKEAVLV 3520
EE+K E+E K +I IKE++ L E L +K +Q E + V
Sbjct: 12350 NEMEEIKCELETKRIEI---IKEQKRLEESLNTVNEERQYLEIVRVDYEKHQQQIEEMRV 12406
Query: 3521 EKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEEL-------Q 3679
+ E ++ L+ + R++ E+ +D++ L +E K + EEL Q
Sbjct: 12407 KTKMERDELDQLM-AKMLMDRKENERSKDMIGLLKKEMEQTKFNLDAQEEELKLEKQKIQ 12465
Query: 3680 SKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSE 3808
++++DLE+ E K ++ E EKD +AFE E
Sbjct: 12466 NEKKDLEMFKAEIKREASEVKTLKEQQLEKD--TKAFEALKEE 12506
Score = 105 bits (263), Expect = 1e-19
Identities = 245/1365 (17%), Positives = 518/1365 (37%), Gaps = 201/1365 (14%)
Frame = +2
Query: 320 KIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGLYVSNV 499
K E L+++++ L+ +L + + ED+ N K+ L E L+
Sbjct: 5915 KEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLREDELWQ--- 5971
Query: 500 VSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLE---ETLQYKEEVIL 670
L + Q+ E ++ +SE + K +EDL HKI SL+ E+L+ E
Sbjct: 5972 -----LQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFE 6026
Query: 671 SSHETISERDRLLKDFIHEKDLMQQRAQETEQKLAS------RDNEMMHMVLE----KDN 820
+ E + + L+ E + ++ Q Q++ +D + ++ ++E KD
Sbjct: 6027 NEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDM 6086
Query: 821 IILSLHKQIELQSQNTQSLDCFRRDEIED--------QNIKEEIEKQIVETIYVTQIQEL 976
++ ++ IE + ++ QS E D +KE++EKQ T+ QIQ+
Sbjct: 6087 VLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTL--AQIQKE 6144
Query: 977 GEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEI 1156
E+ + + + EI+ +++ + KQ E+ +L + I N E EI
Sbjct: 6145 REDLEKMNENITREMHEIKHQEEQMN----QKQDELDQL----KTEIQNLQQELEKEKEI 6196
Query: 1157 YENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXX 1336
+L + S+L + N ++++ + L + +++EQ
Sbjct: 6197 IMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQS 6256
Query: 1337 XXTLKASMEM-------------QCSKLKDELEEERGKISENLERISKLQKMNNELAERS 1477
+L ++M + ++K ELE E I + E +++ ++AE
Sbjct: 6257 RKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEEL 6316
Query: 1478 KSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGH 1657
K + V N + + L++ + I K+ ++
Sbjct: 6317 KKERK-DVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKE 6375
Query: 1658 LDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEK----LVNDSLHEVDSAFCSLNSRFYS 1825
D I + L + EI K Q + +S+IE+ ++ D + ++ S SL+ S
Sbjct: 6376 KDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKD-VEDLQSKIISLDRDAES 6434
Query: 1826 LI---HKVDNSGETLRAFVKNIQNQV----AVSQEQHIEHQCKEELEGHIADLVLND--- 1975
L +N E L+ ++ + + E E Q EE+ + + N+
Sbjct: 6435 LKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQ 6494
Query: 1976 FSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAE-------------- 2113
+ + +K+E D+ D R +L +LK + ++L+ E
Sbjct: 6495 LDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLERE 6554
Query: 2114 -EAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTG----------- 2257
+ + + + + + ++E ++ A +++ K++ L +
Sbjct: 6555 ADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLADLQKE 6614
Query: 2258 ----QAFRE--PPKPEDLYTTYSEGKIVEPH----PTEEKKLLAILAFETADA-SDSPLR 2404
+ RE + ED+ + K+ E TE +K + + E + S+
Sbjct: 6615 KRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAAM 6674
Query: 2405 NWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXX 2584
K+ ++ K K+ ++E+Q K EI K LL N++N L
Sbjct: 6675 IREKQNMMTELK------KKSEDVEMQMK--EILTEKELLHNDRNLLKKDVEDLQQKLMS 6726
Query: 2585 XVAEITG-KFEKVLQEN----------------------KLLPVEEVQRYKMLCVLKEEL 2695
+ K +K EN KL E QR + ++
Sbjct: 6727 IERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKE 6786
Query: 2696 QSKIDSLLKEIKEK-----DSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITD 2860
+ +I++L++EIK+K +S +++ EK + +S D + +S K ++E + +
Sbjct: 6787 REEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRS-DLEKAKSQTFKQNKNIEIALAE 6845
Query: 2861 REIMTSVCSDVLTALFVEMVR--EKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLV 3034
+ + + + + ++ +++ + LA +E E ++ +++ E KD LL +
Sbjct: 6846 IQQKRNALEKMSKEISRDRMKLEDEKKEIQLAREELERMHG---DMQRQQEAKDHLLSGI 6902
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGR-----------VFLQS----------------- 3130
+E+ K + I+ + + + P R VF+Q
Sbjct: 6903 TDESLLKKSEAEIVLQPSQVDKAKPARKTEISDSDKQPVFVQQMPEMDLKDALKKDFESE 6962
Query: 3131 -------------------------EEREKIEEQKRVLDQALQECEELKNDIQNKHSDID 3235
+E +K+++ + L + + E+ K D+QN+ +D
Sbjct: 6963 KLDLPKVKDVLPQDQQMKLEQKLIEDEMDKLKQMRAELQKEADQIEKKKQDMQNERQKLD 7022
Query: 3236 SL-------REEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNE 3394
+ R E+LN+++ ++ + ++ E+ N+
Sbjct: 7023 DMAARLQEERRTNERLNEEINIQKVNQQKQATAFQME-------KTDFERIKTEIDQANK 7075
Query: 3395 ELKNEIEKKSTDIDLLIKEKEELNERLAYTQK-------------AMEQKEAVLVEKLFE 3535
EL ++ EK I + KE+E L E A K + E + A L E + +
Sbjct: 7076 ELADQQEKNKKTITEMQKERETLEEMRANISKQVETITNENKSLSSRESELAKLQEDILQ 7135
Query: 3536 GEQKILLLESS---QSATREQTEKYRDLLNSLTEEHADLKKQFLSATE----ELQSKERD 3694
+Q++ L+++ + +Q + DLL ++ D K ++ E E+ ++ R+
Sbjct: 7136 QQQEMDELKNTIMMEMCQLDQRQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQTRN 7195
Query: 3695 LEVAMTETKFLKEKL------LVSDENLKEKDLQLRAFEIANSEK 3811
++ M K KE L +++L EK+ +L + +++K
Sbjct: 7196 IKSDMVSLKMEKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDK 7240
Score = 104 bits (259), Expect = 3e-19
Identities = 222/1208 (18%), Positives = 484/1208 (40%), Gaps = 43/1208 (3%)
Frame = +2
Query: 326 AETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGLYVSNVVS 505
+E + ME + TLK L +D + ++E+ K+ L+ + +G+ V
Sbjct: 10152 SEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNV----- 10206
Query: 506 DAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHET 685
Q++E K + E +N K +I + ++ ++E L++ +
Sbjct: 10207 ----------QKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEEDLTNQKK 10256
Query: 686 ISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQN 865
+ E + L++ ++ K + + E E H + +K + +L +QI + +
Sbjct: 10257 MEEERKCLEE-VNGKIIEMKTKAELEH----------HEINQKIEELQTLQEQIMKEKEK 10305
Query: 866 TQSLDCFRRDEIED-QNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLK 1042
+++ + E ED IK E+ ++ E + + ++L ++ ++ E +++++ +K
Sbjct: 10306 AEAMTIKLKMEREDLDQIKSELVREKTEVDH--EQKKLNDDIKMIEQE----KEDLEKMK 10359
Query: 1043 DECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSK 1222
E ++ + E S+L + ++++ + + + + EI E E+ +Q +++
Sbjct: 10360 SEIMTQKQEMEKERSELDNKIQQTDLEKH-DIEKSKEIVEKLMFEVEEQRHEIQLQKEEL 10418
Query: 1223 NSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELE-- 1396
+ +A D L ++LQ + TLK ME K K+E++
Sbjct: 10419 DIERQKIADEQDLLIQNKSELQNENERIRNINEVIKKERETLK-EMEAHLEKEKEEMKSI 10477
Query: 1397 -EERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAF 1573
EE + E+LE++S K N+ + K ++ +
Sbjct: 10478 TEETRRQKEDLEKMSTDIKEQNQ--DLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQVS 10535
Query: 1574 GSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHI 1753
K E+LT Q + ++K E +T + + + + + E K +K + E +
Sbjct: 10536 KQKEEDLTKQKEMKE---ERKSLE-----ETKARIIEMKTKAELEDIKKEKEKEEEEEEM 10587
Query: 1754 EKLVNDSLHEVDSAFCSLNSRFYSLIH---KVDNSGETLRAFVKNIQNQVA--VSQEQHI 1918
V E+D L + H K+++ + + +N++ + + Q Q +
Sbjct: 10588 RVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKSEIMKQRQQM 10647
Query: 1919 EHQCKEELEGHIADLVLN--DFSND-------ILSWSRRKEEAVVHDDEFDAERIALLNE 2071
E + + ELE I + D N ++ +K E +E D ER + +E
Sbjct: 10648 EEE-RSELENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADE 10706
Query: 2072 LKSLHQDL-ELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRH 2248
L Q+ EL E +++L+ + + + +++ K+ E V ++R L+
Sbjct: 10707 QDLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKE-EIKSVSEETRRLKED 10765
Query: 2249 STGQAFREPPKPEDLYTTYSEGKIVEPHPTEE----KKLLAILAFETADASDSPLRNWPK 2416
+ + +DL ++ ++E E K+L + A S ++ PK
Sbjct: 10766 LEKMSTDVNKQNKDLM---NQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPK 10822
Query: 2417 EQLLGHFKQSFAGLKREY-ELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVA 2593
E+ + ++S K E++ + + EEI K E+ +
Sbjct: 10823 EKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELY 10882
Query: 2594 EITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLS 2773
+I + E+V E + KM+ KE+L+ ++K+ ++ + L K+
Sbjct: 10883 QIKSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKI- 10941
Query: 2774 DALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLAT 2953
++++L KH D+E +++ L VE V E+ + L
Sbjct: 10942 -----------QQTNLEKH--DIEKS-----------KEIVEKLMVE-VEEQRKDIQLQK 10976
Query: 2954 KEQETVNQKQMSLRKML-EDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQS 3130
+E + QK + +L ++K KL E++R + E++K+E E
Sbjct: 10977 EELDIERQKIADEQNLLVQNKAKL-------QNENERIKKVDEEIKKERET-------LR 11022
Query: 3131 EEREKIEEQKRVLDQALQECEELKNDIQNKHSDI-----------DSLREEQEKLNKQLR 3277
E ++++K L ++E + K D++ +DI D L +E+E++N ++
Sbjct: 11023 EMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREEINHEMT 11082
Query: 3278 CMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEEL-KNEIEKKSTDID------ 3436
+ +D ++ E+L K E+E++ ++
Sbjct: 11083 ---------------------QLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARI 11121
Query: 3437 LLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLN 3616
+ +K K EL E + ++ E++ V+VE +++ ++S R + + + LN
Sbjct: 11122 IEMKTKAELQEIMQEKEEEDEEEMRVIVEM---EREELNQIKSELKRVRSEIDHEQKKLN 11178
Query: 3617 SLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEI 3796
D KK E+L+ + ++ MT+ + ++E+ D +K+ DL+ +I
Sbjct: 11179 -------DDKKIIEQEKEDLEKMKSEI---MTQRQQMEEERSELDNKIKQTDLE--RHDI 11226
Query: 3797 ANSEKQYQ 3820
NS++ Q
Sbjct: 11227 ENSKEIVQ 11234
Score = 102 bits (255), Expect = 1e-18
Identities = 220/1188 (18%), Positives = 496/1188 (41%), Gaps = 26/1188 (2%)
Frame = +2
Query: 296 DTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVE 475
D +S+ +AE E++ I L++ +L ++ + + E+ + ++ +D +
Sbjct: 2071 DKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIR 2130
Query: 476 SGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYK 655
G+ + + + + ++ A +++ + K I+++ +++ QY
Sbjct: 2131 VGIEKQEITFKDL--------KADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQKERQYM 2182
Query: 656 EEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLAS--RDNEMMHMVLEKDNIIL 829
+ ++ + D + + E+ ++ + E EQ+ + D + EK+NII
Sbjct: 2183 DRLVEEIEKRTKALDEMQMEVDKERQEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQ 2242
Query: 830 SLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLES 1009
+ +I+ +S N E++ +NI +E TI+ EL +EH LR
Sbjct: 2243 A---EIQKESDNL---------ELQSENISKE------RTIF-----ELEKEHLGLRENE 2279
Query: 1010 AKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQ 1189
A+Y+ Q DE K ++ ++ ++ ++ E + TA E T
Sbjct: 2280 AEYK---QKQIDELQNKLRMEKVQVEQMQ--ADKDQQRKKAEYVKTARGRETT------A 2328
Query: 1190 ISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQ 1369
+ + R +M +SL + + + + EQ +K E +
Sbjct: 2329 LEEQRQEM-------ESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKYKE-K 2380
Query: 1370 CSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXX 1549
K ++L+ +R + ++++ ++ E ER K + I
Sbjct: 2381 LDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEI---QKPAVYTETYMLETQ 2437
Query: 1550 XXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKV 1729
VV + +L+E+ +IN S ++K+++ + IS ++ + EK +
Sbjct: 2438 KPVVEKSKTDELDEVRKKINADLSEVEKQKSALVQMNLKISQEESYVKK-----EKDRLK 2492
Query: 1730 LQSFESHIE-KLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQ 1906
LQ E +++ +N +E+D + + L + +D + + +V +++
Sbjct: 2493 LQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMD----------RLEKEKVEITK 2542
Query: 1907 EQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLH 2086
E+ ++ + E++ A S D++ K+E + D + R L EL+ +
Sbjct: 2543 EKQRVNEMQNEVKRKNA-------SVDLI-----KQEVLREQDHIENSREILNRELEKIK 2590
Query: 2087 QDLELLKAE-EAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRAL---RRHST 2254
+ +L E EA+ +G + + +Q+ EA D + + R + RR++
Sbjct: 2591 EKKTILAEEFEALDDKKEMIGKEMQRLGKMKAELQK----EAEDTEKQRRDIDNDRRNNE 2646
Query: 2255 GQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGH 2434
+ + +D+ T+ + E + +K+ L +T + L E +
Sbjct: 2647 EMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLE-SDRDTLEKERFDLEKTKTE--MKD 2703
Query: 2435 FKQSFAGLKREYEL---ELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITG 2605
++ R++E+ E+Q++ E + LK L +K L A+I+
Sbjct: 2704 LEKQLESQSRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEK----ADISL 2759
Query: 2606 KFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSN--SKVLAEKLSDA 2779
+ E Q K E + + ++ +K+E+ + L +KE ++N K + E D
Sbjct: 2760 REELEEQSEK----EGIDKTRVR--IKQEMDELEQTRLNVVKELENNELQKQIIEDERDK 2813
Query: 2780 LKKSADHAQRES-HLLKHIADLEAGITDREIMT----SVCSDVLTALFVEMVREKEFSLS 2944
+++ Q+E+ K D+E + E M + D+ T+ + +R++E +L
Sbjct: 2814 IEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETS--TDRIRDEEANLR 2871
Query: 2945 LATK----EQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPG 3112
+ + +++T+ +++ L+K + L + +N++H+ Q+A ++K
Sbjct: 2872 VLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQK---------- 2921
Query: 3113 RVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXX 3292
ERE +E+ K L + ++ E+ ++ + + +DI SLREE ++ +++
Sbjct: 2922 -------EREILEQLKLTLSKQKEDLEKERDCFEKEKADI-SLREELQEQSER------- 2966
Query: 3293 XXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELK-NEIEKKSTDIDLLIKEKEELNE 3469
I +D ++ N +EL+ NE++K+ ++ E++++ +
Sbjct: 2967 --------EGIGKTRVRIKKEMDELKQTRLNVVKELENNELQKQ-----IIEDERDKIEQ 3013
Query: 3470 RLAYTQKAME--QKEAVLVEK-LFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHAD 3640
A QK E +K+ +EK E+ ++ L++ + T++ RD E + +
Sbjct: 3014 IKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETSTDRIRD-----EEANLE 3068
Query: 3641 LKKQFLSATEELQSKER-DLEVAMTETKFLKEKLLVSDENLKEKDLQL 3781
++KQ L + + KER DLE TE LK++L + +++ ++QL
Sbjct: 3069 VQKQRLESDRDTLEKERFDLEKTKTEMGNLKKQL---ESQIRQHEIQL 3113
Score = 101 bits (252), Expect = 2e-18
Identities = 227/1221 (18%), Positives = 499/1221 (40%), Gaps = 47/1221 (3%)
Frame = +2
Query: 257 SVTSFIEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLE 436
SVT + + LD S + +T+E + I G L+ + F+L + LLE
Sbjct: 8434 SVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFELKKGEQ----LLE 8489
Query: 437 DIRNTKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLN 616
KD L E+G V EE K + + N + +K ED++
Sbjct: 8490 ---KQKDELK--ENGWIV-----------------EEIKNKKDSLEKINMEILRKNEDMD 8527
Query: 617 HKIWSLEETLQYKEEVILSSHETISERDRL---LKDFIHEKDLMQQRAQETEQKLASRDN 787
+ L Q K+E+ L E +R+ L ++ HEK M+ E + D
Sbjct: 8528 KEKGKLR---QEKQEMDLFRSELQRQREDLETSIQKLTHEKREMEVLRSEIVLEKKDLDQ 8584
Query: 788 EMMHMVLEKDNI------ILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVET 949
+M ++ ++D + I + +I+ + Q + L RD + Q+ +++ E+ + T
Sbjct: 8585 KMKQVIRKRDEMEKIRFDIANARVEIDGERQELEIL----RDNV--QSARQDFERLVERT 8638
Query: 950 IYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSN 1129
+ + + + L LE K ++ +++LK E + + EI +
Sbjct: 8639 ANLEVEESAATDIERLVLEVVKIREMVRNLKGEMERRMEESKVEIDE------------- 8685
Query: 1130 LESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLA---SRIDFLSSECNKLQEQXX 1300
EI+++ + L I Q+R ++ + I++ S ++ + +E + Q++
Sbjct: 8686 ------KEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQE-- 8737
Query: 1301 XXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSK 1480
+ SM K K+ELE+ + I+ E I +++ EL E
Sbjct: 8738 ----------------EESMREILQKEKEELEQLKKDINREKEDI----EISRELVESEI 8777
Query: 1481 SQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHL 1660
+ + + +L+ +T+++ +++ ++V +
Sbjct: 8778 YEGEVKGFTDV-----------------QKYKEELQIVTEELLTKKRNLEQLNSDVQHLM 8820
Query: 1661 DTISSLQTVLSNQKFEIE----KSQKVLQSFESHIEKLVNDS--LHEVDSAFCSLNSRFY 1822
T+ + +K E+E + QK Q E +KL + + E++ +L S
Sbjct: 8821 QTLEEVDIQYIKKKAELEHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINM 8880
Query: 1823 SLIHK---VDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDIL 1993
++ K ++ E LR + + Q Q ++E+E L++ +
Sbjct: 8881 EILQKREDMEKEKENLRREKQETELFRGELQRQ------RDEVESSRQALIMEKDQFKLK 8934
Query: 1994 SWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYF 2173
+R E + + E L+++ DLE +A+ A +SL++ + K
Sbjct: 8935 IDHQRNEMSAAFEKEH--------KRLENMENDLENQRAKLA-ESLNDAAKMEQKLQQMK 8985
Query: 2174 SQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKL 2353
++L +E + E K+ ++ + R+ + +I + H +KK
Sbjct: 8986 NELNKEKEQVEEMKQMVKTERVKIEQEKEEMRKQTQ-----------EIEDGHEKLQKKT 9034
Query: 2354 -LAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELE---LQRKTEEIYDLKRL 2521
+A + A++ L++ + L +Q E E + L R + E+ D K
Sbjct: 9035 EIADKLLQDANSESDRLKDLSMK--LQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIR 9092
Query: 2522 LLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQS 2701
L N+++ + + K E++++E + L + +Q+ + + K ++++
Sbjct: 9093 LKNDRDAYEKD-----------MTHLELKREELVRETEDLERKILQQREQDEMAKRDIEN 9141
Query: 2702 KIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSV 2881
+ ++L E+ + D +L ++ A + H++R+ LL L+ + +E
Sbjct: 9142 QTEAL--EVMKVD----ILKKRNEFAKEMENVHSERQKLLL-----LQGALQSQE----- 9185
Query: 2882 CSDVLTALFVEMVREKEFSLSLATKEQ---------ETVNQKQMSLRKMLEDKDKLLCLV 3034
S++ +F+E +K + A E+ ETV +Q RK++E+ +
Sbjct: 9186 -SELENRVFME--EQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQR----E 9238
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVFLQSE----EREKIEEQKRVLDQALQECEELK 3202
E+ + K QI E+ K++ +N + Q E E+ +E++K L++ E +E++
Sbjct: 9239 KEQLEISKNQI---EQEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQ 9295
Query: 3203 NDIQNKHSDIDS----LREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQ 3370
N I+ + D+++ + E++++ ++ R + + +
Sbjct: 9296 NAIRKEREDLENCWVEIEGEKKRMEEETRRLEMHR------------------EEIKKVD 9337
Query: 3371 LELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKI 3550
EL+ E +++ EK + ++ L++ K E+ +K ++ + ++
Sbjct: 9338 SELQKSRENIESREEKINNKMEELLQMKVEMGRTKEEIEKESQRLQDATID--------- 9388
Query: 3551 LLLESSQSATREQTEKYRDLLN-SLTEEHADLKKQFLSAT----EELQSKERDLEVAMTE 3715
LE++++ + Q +K+ D+++ + E+ ++K Q T EE++ K +DLE+ M +
Sbjct: 9389 --LENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQLDKETKRLSEEIELKVKDLEMEMAD 9446
Query: 3716 TKFLKEKLLVSDENLKEKDLQ 3778
K K++ + + L EK+ Q
Sbjct: 9447 MKRQKQE-IEDTKGLLEKEKQ 9466
Score = 99.8 bits (247), Expect = 9e-18
Identities = 238/1239 (19%), Positives = 502/1239 (40%), Gaps = 68/1239 (5%)
Frame = +2
Query: 302 RKSLETKIAE-TLERMEIHEGDTANTLKNMNFD------------LGQDNPGVPGLLEDI 442
+ LET+I + TLE+ ++ + L+ + D + + + E+I
Sbjct: 8188 KDDLETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANATEEI 8247
Query: 443 RNTKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNK-KIEDLNH 619
+ L+ + + + + + +L + ++EE AA D E +L KI ++
Sbjct: 8248 NRERQELEILRNNVQSARHDFELLLERTANLEDEES----AATDIERLVLEVVKIREMVR 8303
Query: 620 KIWSLEETLQYKEEVILSSHETI-SERDRLLKDFIHEKDLMQQRAQETEQ-KLASRDNEM 793
+ E K +V + E SE R ++D ++ + +E E+ + R+ E
Sbjct: 8304 NLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEK 8363
Query: 794 MHMVL-EKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQ 970
M L EK S+ + + + + + L +DEI + EI +++VE V +
Sbjct: 8364 MRAELAEKQQEQESMREMLHKEREELEQL----KDEINREKEDVEIRRELVEA--VIDKE 8417
Query: 971 ELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQ---AEISKLSHTLEESIMNSNLESL 1141
E+ E D+ KY++E+QS+ +E K+ +++ L T+EE + +
Sbjct: 8418 EMKEFTDI-----QKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKR- 8471
Query: 1142 FTAEIYENTFR-ELGDQISQLRNDMYSKNSYI-DSLASRIDFLSSECNKLQEQXXXXXXX 1315
AE+ F + G+Q+ + + D +N +I + + ++ D L K+ +
Sbjct: 8472 --AELEGIGFELKKGEQLLEKQKDELKENGWIVEEIKNKKDSLE----KINMEILRKNED 8525
Query: 1316 XXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSI 1495
K M++ + EL+ +R E+LE + +QK+ +E E ++ I
Sbjct: 8526 MDKEKGKLRQEKQEMDL----FRSELQRQR----EDLE--TSIQKLTHEKREMEVLRSEI 8575
Query: 1496 XXXXXXXXXXXXXXXXXXXXVVNMAFG------------SKLEELTDQINIFNSVIDKKE 1639
+ + F +LE L D + ++
Sbjct: 8576 VLEKKDLDQKMKQVIRKRDEMEKIRFDIANARVEIDGERQELEILRDNVQSARQDFERL- 8634
Query: 1640 AEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSA--FCSLNS 1813
E + +L+ S T + E+ K ++++++ + +E+ + +S E+D F S
Sbjct: 8635 VERTANLEVEESAATDIERLVLEVVKIREMVRNLKGEMERRMEESKVEIDEKEIFKSEIQ 8694
Query: 1814 RFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLV------LND 1975
R I ++ + L+ ++N + + ++ E + K++ E + +++ L
Sbjct: 8695 RLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQEEESMREILQKEKEELEQ 8754
Query: 1976 FSNDILSWSRRKEEAVVHDDEFDAE----RIALLNELKSLHQDLELLKAEEAVKSLSNNV 2143
DI +R KE+ + + ++E + +++ ++L+++ E K N+
Sbjct: 8755 LKKDI---NREKEDIEISRELVESEIYEGEVKGFTDVQKYKEELQIVTEELLTKK--RNL 8809
Query: 2144 GVSTKGIHYFSQLIQEGKDGEASDVQG-KSRALRRHSTGQAFREPPKPEDLYTTYSEGKI 2320
+ + Q ++E D+Q K +A H T + + E E
Sbjct: 8810 EQLNSDVQHLMQTLEE------VDIQYIKKKAELEHITSEIQKREQILEKQKKKLEENGW 8863
Query: 2321 VEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYEL---ELQRK 2491
+ EE +++ + T ++ + + K + + K++ K+E EL ELQR+
Sbjct: 8864 I----IEEIEMMKV----TLESINMEILQ--KREDMEKEKENLRREKQETELFRGELQRQ 8913
Query: 2492 TEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKM 2671
+E+ ++ L+ EK+ +F+ + QR +M
Sbjct: 8914 RDEVESSRQALIMEKD----------------------QFKLKIDH---------QRNEM 8942
Query: 2672 LCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAG 2851
++E +++++ +++ + + LAE L+DA K Q ++ L K +E
Sbjct: 8943 SAAFEKE-HKRLENMENDLENQRAK---LAESLNDAAKMEQKLQQMKNELNKEKEQVEE- 8997
Query: 2852 ITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCL 3031
++ V++ +EKE + T+E E ++K L+K E DKLL
Sbjct: 8998 ----------MKQMVKTERVKIEQEKE-EMRKQTQEIEDGHEK---LQKKTEIADKLLQD 9043
Query: 3032 VGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEE----L 3199
E+ K L+ +++ E ++E +KR LD+ +E ++ L
Sbjct: 9044 ANSESDRLKDLSMKLQMQRQDIEKT----------NTEMETKKRSLDRMSRELQDDKIRL 9093
Query: 3200 KNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLEL 3379
KND D+ L ++E+L ++ + +L+ L+
Sbjct: 9094 KNDRDAYEKDMTHLELKREELVRE-------------------------TEDLERKILQQ 9128
Query: 3380 RNYNEELKNEIEKKSTDIDLL-----------IKEKEELN---ERLAYTQKAMEQKEAVL 3517
R +E K +IE ++ ++++ KE E ++ ++L Q A++ +E+ L
Sbjct: 9129 REQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQESEL 9188
Query: 3518 VEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDL 3697
++F EQK L + +TE+ R L ++E + ++ EELQ ++ L
Sbjct: 9189 ENRVFMEEQKHL------KQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQREKEQL 9242
Query: 3698 EVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQ 3814
E++ + + K+ L NL E+ L+ E AN E +
Sbjct: 9243 EISKNQIEQEKKDLQNMKSNL-ERQLESLRHEKANVEDE 9280
Score = 99.0 bits (245), Expect = 1e-17
Identities = 237/1220 (19%), Positives = 485/1220 (39%), Gaps = 57/1220 (4%)
Frame = +2
Query: 305 KSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGL 484
K + +IAE L+++ GD +N +L ++ + + + ++ +D+ + L
Sbjct: 1961 KKSQDEIAEQLKQV----GDMMQFTQNEKDNLDRERAAI--IEQKLQMERDMTHLLNREL 2014
Query: 485 YVSNVVSDAVLNGVVSAQE------------EEFKEALAAKDSENFLLNKKIEDLNHKIW 628
+V VLN ++ E+ K L + E L + I + K+
Sbjct: 2015 ESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLE 2074
Query: 629 SLEETLQYKEEVILSSHETISERDRLLKDFIH---EKDLMQQRAQETEQKLASRDNEMMH 799
S+ +TL E + +T++E+ +L + E+D + A+ET++K D + +
Sbjct: 2075 SVLQTLAEDTEKLRI--DTLAEKQKLEDAAVELQKERDEIMNIAEETKRK--REDVDKIR 2130
Query: 800 MVLEKDNIILS-----LHKQIELQSQNTQSLDCFRRD--EIEDQNIKEEIEKQIVETIYV 958
+ +EK I L K+ + Q++ ++D ++D ++ + E+Q ++ + V
Sbjct: 2131 VGIEKQEITFKDLKADLQKEAAIVENQRQAV---QKDIQNVKDMEVQIQKERQYMDRL-V 2186
Query: 959 TQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSK------------------QAEI 1084
+I++ + D +++E K + E++S +DE +E SK QAEI
Sbjct: 2187 EEIEKRTKALDEMQMEVDKERQEVESKRDELE-QETSKLREDEDEFSRQKEKNNIIQAEI 2245
Query: 1085 SKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLR-NDMYSKNSYIDSLASRIDF 1261
K S LE + + N+ E T EL + LR N+ K ID L +++
Sbjct: 2246 QKESDNLE--LQSENISK-------ERTIFELEKEHLGLRENEAEYKQKQIDELQNKLRM 2296
Query: 1262 LSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISK 1441
+ ++Q +K + + + L+++ +E + E E + K
Sbjct: 2297 EKVQVEQMQADKDQQRKKAEY-------VKTARGRETTALEEQ-RQEMESLREEYENVEK 2348
Query: 1442 LQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNS 1621
+K NE E +S+ + E+L Q +F
Sbjct: 2349 QKKHVNEQKELFESRMKSLEMENEAMKKYKEK-----------LDKEYEDLQFQRQLFEK 2397
Query: 1622 VIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFC 1801
I + E+ + I + L QK + +L++ + +EK D L EV
Sbjct: 2398 EIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDEV----- 2452
Query: 1802 SLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFS 1981
+ + + +V+ L +Q + +SQE+ + K+ L+ L N+ +
Sbjct: 2453 --RKKINADLSEVEKQKSAL------VQMNLKISQEESYVKKEKDRLK-----LQENEQN 2499
Query: 1982 NDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQD-LELLKAEEAVKSLSNNVGVSTK 2158
+ + ++ E E + ++ L N + L ++ +E+ K ++ V + N V
Sbjct: 2500 MQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITKEKQRVNEMQNEVKRKNA 2559
Query: 2159 GIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPT 2338
+ Q + +D ++ L R E
Sbjct: 2560 SVDLIKQEVLREQD----HIENSREILNR--------------------------ELEKI 2589
Query: 2339 EEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKR 2518
+EKK + FE D K++++G Q +K E LQ++ E+ +R
Sbjct: 2590 KEKKTILAEEFEALD---------DKKEMIGKEMQRLGKMKAE----LQKEAEDTEKQRR 2636
Query: 2519 LLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQ 2698
+ N++ V ++ + + + + EE L V K+ L+
Sbjct: 2637 DIDNDRRN-----------NEEMVIKLQNEKKDIETSTDRIRDEEAN----LRVQKQRLE 2681
Query: 2699 SKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTS 2878
S D+L KE + + + + L+K Q ES +H L +REI
Sbjct: 2682 SDRDTLEKERFDLEKTKTEMKD-----LEK-----QLESQSRQHEIQLVEIQKEREI--- 2728
Query: 2879 VCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQ--MSLRKMLEDKDKLLCLVGEENKE 3052
L L + + ++KE KE++ +++ +SLR+ LE++ + + +
Sbjct: 2729 -----LEQLKINLSKQKED----LEKERDCFEKEKADISLREELEEQSEKEG-IDKTRVR 2778
Query: 3053 HKRQIAILEKLK----EETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNK 3220
K+++ LE+ + +E ENN + + +ER+KIE+ K L + ++ E+ + DI+N
Sbjct: 2779 IKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIEND 2838
Query: 3221 HSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEEL 3400
+ + + + + K + L+ + +L+ N E+
Sbjct: 2839 RRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEM 2898
Query: 3401 KN-----EIEKKSTDIDLL-IKEKEELNERLAYTQKAMEQKEAVLVEK-LFEGEQKILLL 3559
K+ E + + +I L I+++ E+ E+L T +QKE + E+ FE E+ + L
Sbjct: 2899 KDLEKQLESQNRQHEIQLAEIQKEREILEQLKLT--LSKQKEDLEKERDCFEKEKADISL 2956
Query: 3560 --ESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKE 3733
E + + RE K R + +E +LK+ L+ +EL++ E ++ E +++
Sbjct: 2957 REELQEQSEREGIGKTR---VRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQ 3013
Query: 3734 KLLVSDENLKEKDLQLRAFE 3793
+ ++ + Q R E
Sbjct: 3014 IKAELQKEAEDTEKQRRDIE 3033
Score = 94.4 bits (233), Expect = 4e-16
Identities = 243/1244 (19%), Positives = 500/1244 (40%), Gaps = 68/1244 (5%)
Frame = +2
Query: 293 LDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTV 472
+ T+ + KI+E + + + + +K +DL Q + D+ + + +
Sbjct: 1897 IKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQ-------MQTDLNRQQKEMQDI 1949
Query: 473 ESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQY 652
++ +++ + + +Q+E ++ D F N+K + +E+ LQ
Sbjct: 1950 QNAVFMEK-------SELKKSQDEIAEQLKQVGDMMQFTQNEKDNLDRERAAIIEQKLQM 2002
Query: 653 KEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILS 832
+ ++ + + + K+ ++EK L++ + + +D E M + LE++
Sbjct: 2003 ERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRDM--QDLEQMKINLEREK---- 2056
Query: 833 LHKQIELQSQNTQSLDCFRRDEIED--QNIKEEIEKQIVETIYVTQIQELGEEHDLLRLE 1006
++++LQ Q+ +D++E Q + E+ EK ++T+ + Q+L + +E
Sbjct: 2057 --EEMQLQRQSIAE----EKDKLESVLQTLAEDTEKLRIDTL--AEKQKLEDA----AVE 2104
Query: 1007 SAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLE-ESIMNSNLESLFTAE--IYENTFRE 1177
K +DEI ++ +E K + ++ K+ +E + I +L++ E I EN +
Sbjct: 2105 LQKERDEIMNIAEETKRK----REDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQA 2160
Query: 1178 LGDQISQLRN---DMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTL 1348
+ I +++ + + Y+D L I+ + +++Q +
Sbjct: 2161 VQKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVD---------------- 2204
Query: 1349 KASMEMQCSKLKDELEEERGKISENLERISKLQKMNNEL-AERSKSQNSIXXXXXXXXXX 1525
K E++ + DELE+E K+ E+ + S+ ++ NN + AE K +++
Sbjct: 2205 KERQEVESKR--DELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKE 2262
Query: 1526 XXXXXXXXXXV---VNMA--FGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVL 1690
+ N A +++EL +++ + +++ +A+ ++T
Sbjct: 2263 RTIFELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTAR 2322
Query: 1691 SNQKFEIEKSQKVLQSFESHIE------KLVNDSLHEVDSAFCSL---NSRFYSLIHKVD 1843
+ +E+ ++ ++S E K VN+ +S SL N K+D
Sbjct: 2323 GRETTALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKYKEKLD 2382
Query: 1844 NSGETL----RAFVKNIQNQVAVSQ--EQHIEHQCKE--------ELEGHIADL---VLN 1972
E L + F K IQ Q ++IE + KE E ++ + V+
Sbjct: 2383 KEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVE 2442
Query: 1973 DFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVS 2152
D L R+K A + + E + +N LK ++ + K ++ +K N +
Sbjct: 2443 KSKTDELDEVRKKINADLSEVEKQKSALVQMN-LKISQEESYVKKEKDRLKLQENEQNMQ 2501
Query: 2153 TKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPH 2332
SQL K E + Q + +R + + + E + T + ++ E
Sbjct: 2502 ------MSQL--NAKQNELDERQAEMEKQKREL--ENVMDRLEKEKVEITKEKQRVNEMQ 2551
Query: 2333 PTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKT------ 2494
++K ++ D + +EQ H + S L RE E ++KT
Sbjct: 2552 NEVKRKNASV---------DLIKQEVLREQ--DHIENSREILNRELEKIKEKKTILAEEF 2600
Query: 2495 EEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKML 2674
E + D K ++ E L AE+ + E ++ + + + +M+
Sbjct: 2601 EALDDKKEMIGKEMQRL-----------GKMKAELQKEAEDTEKQRRDIDNDRRNNEEMV 2649
Query: 2675 CVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLS---DALKKSADHAQRESHLLKHIADLE 2845
L+ E + I++ I+++++N +V ++L D L+K ++ +K DLE
Sbjct: 2650 IKLQNE-KKDIETSTDRIRDEEANLRVQKQRLESDRDTLEKERFDLEKTKTEMK---DLE 2705
Query: 2846 AGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLL 3025
+ + R+ E L KE+E + Q +++L K ED +K
Sbjct: 2706 KQLESQS------------------RQHEIQLVEIQKEREILEQLKINLSKQKEDLEKER 2747
Query: 3026 CLVGEENKEHKRQIAILEKLKEETEN---NPGRVFLQSE-------------EREKIEEQ 3157
+E K I++ E+L+E++E + RV ++ E E E E Q
Sbjct: 2748 DCFEKE----KADISLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQ 2803
Query: 3158 KRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXX 3337
K++++ + E++K ++Q + D + R++ E + M
Sbjct: 2804 KQIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRI 2863
Query: 3338 XXISSNLDSMQLELRNYNEELKNE---IEKKSTDIDLLIKEKEELNERLAYTQKAMEQKE 3508
+NL ++ L + + L+ E ++K +T++ L K+ E N R Q A QKE
Sbjct: 2864 RDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQN-RQHEIQLAEIQKE 2922
Query: 3509 AVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKE 3688
++E+L K+ L S +E EK RD +E AD +S EELQ +
Sbjct: 2923 REILEQL-----KLTL-----SKQKEDLEKERDCFE---KEKAD-----ISLREELQEQS 2964
Query: 3689 RDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQYQ 3820
+ T + KE + LK+ L + E+ N+E Q Q
Sbjct: 2965 EREGIGKTRVRIKKEM-----DELKQTRLNV-VKELENNELQKQ 3002
Score = 94.0 bits (232), Expect = 5e-16
Identities = 221/1220 (18%), Positives = 488/1220 (40%), Gaps = 53/1220 (4%)
Frame = +2
Query: 284 DGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLL 463
DG + + ++ E+L + +GD L+ M D + + + + + + L
Sbjct: 9974 DGKRNEINKEQQRLEESLRAINEEKGD----LEIMRADYEKQEQQIEEMRVEAKMERKEL 10029
Query: 464 DTVESGLYVSNVVSD---AVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSL 634
D ++S L D LN + E+E + L SE +++ED
Sbjct: 10030 DQIKSELEKDKTEIDYEWKKLNNDRNMIEKE-RNDLEKMKSELMTQRQQMED-------- 10080
Query: 635 EETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEK 814
+ E+ E +E+D++ K+ K+++++ E E++ + + LE+
Sbjct: 10081 -----ERSELDQKIKEANTEKDKIEKN----KEIVERLMAEVEEQRNDFKLKKEELALER 10131
Query: 815 DNII----LSLHKQIELQSQNTQ----------SLDCFRRDEIEDQNIKEEIEKQIVETI 952
NI+ L + ELQ+++ Q + + E Q K+EI+ I ET
Sbjct: 10132 QNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETS 10191
Query: 953 YVTQ-IQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSN 1129
+ ++++ ++ + E +D ++ ++E + K Q I + + + +
Sbjct: 10192 RQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQ-KEED 10250
Query: 1130 LESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXX 1309
L + E E+ +I +++ ++ I+ + L + K +E+
Sbjct: 10251 LTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAMT 10310
Query: 1310 XXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISK----LQKMNNELA--- 1468
+K+ + + K E++ E+ K++++++ I + L+KM +E+
Sbjct: 10311 IKLKMEREDLDQIKSELVRE----KTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQK 10366
Query: 1469 -ERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAE 1645
E K ++ + V + F ++EE +I + +D + +
Sbjct: 10367 QEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMF--EVEEQRHEIQLQKEELDIERQK 10424
Query: 1646 VSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYS 1825
++ D + ++ L N+ I +V+ K ++L E+++ S
Sbjct: 10425 IADEQDLLIQNKSELQNENERIRNINEVI--------KKERETLKEMEAHLEKEKEEMKS 10476
Query: 1826 LIHKVDNSGETLRAFVKNI--QNQVAVSQEQHIEHQCKEELEGHIADLV--LNDFSNDIL 1993
+ + E L +I QNQ + Q +E + KE++ L +++F +
Sbjct: 10477 ITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQE-KEDINHEWTQLQQRIDEFDAQV- 10534
Query: 1994 SWSRRKEEAVVHDDEFDAERIAL------LNELKSLHQDLELLKAEEAVKSLSNNVGVST 2155
S++KEE + E ER +L + E+K+ +LE +K E+ + + V
Sbjct: 10535 --SKQKEEDLTKQKEMKEERKSLEETKARIIEMKT-KAELEDIKKEKEKEEEEEEMRVKV 10591
Query: 2156 KGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHP 2335
+ DG+ D + KS R S + E K D + KI+E
Sbjct: 10592 E------------MDGKELD-RIKSELKRERS--EIDHEQKKLND------DKKIIEQEK 10630
Query: 2336 TEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLK 2515
+K+ K +++ +Q E EL+ K ++ Y K
Sbjct: 10631 QNLEKM--------------------KSEIMKQRQQM-----EEERSELENKIKQTYIEK 10665
Query: 2516 RLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENK---LLPVEEVQRYKMLCVLK 2686
+ N K EI K ++E K EE+ + +
Sbjct: 10666 CDIENSK-------------------EIVQKLMVEVEEQKHEIQFQKEELDIERQKIADE 10706
Query: 2687 EELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDRE 2866
++L + S L+ E+ N + +K + LK+ H +++ +K +++ + +E
Sbjct: 10707 QDLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRL--KE 10764
Query: 2867 IMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEEN 3046
+ + +DV +++ +++ L +E+E +N K L++ +++ D + E++
Sbjct: 10765 DLEKMSTDV-NKQNKDLMNQRD----LLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQD 10819
Query: 3047 -------KEHKRQI------AILEKLKEETENNPGRVFLQSEEREKIEEQKRVL-DQALQ 3184
KE ++ + I K K E E ++EE E+ EE+ RV+ + +
Sbjct: 10820 LPKEKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERK 10879
Query: 3185 ECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDS 3364
E ++K++++ S+ID EQ+KLN ++ + +
Sbjct: 10880 ELYQIKSELERVRSEID---HEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSE 10936
Query: 3365 MQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQ 3544
+ +++ N E K++IEK ++ L+ E EE + + QKE + +E+ ++
Sbjct: 10937 LDNKIQQTNLE-KHDIEKSKEIVEKLMVEVEEQRKDIQL------QKEELDIERQKIADE 10989
Query: 3545 KILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKF 3724
+ LL++ +++ + + E+ + + + +E L++ + L+ ++ +L + ET+
Sbjct: 10990 QNLLVQ-NKAKLQNENERIKKVDEEIKKERETLREMEI----HLKKEKEELRSIIEETQR 11044
Query: 3725 LKEKLLVSDENLKEKDLQLR 3784
KE L ++ E+ L L+
Sbjct: 11045 RKEDLEKMSTDINEQKLHLK 11064
Score = 91.7 bits (226), Expect = 2e-15
Identities = 261/1407 (18%), Positives = 533/1407 (37%), Gaps = 232/1407 (16%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAET-LERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRN 448
+EVE+ RK ++ + E +ER +I D N L L +N + + E+I+
Sbjct: 10963 VEVEE----QRKDIQLQKEELDIERQKI--ADEQNLLVQNKAKLQNENERIKKVDEEIKK 11016
Query: 449 TKDLLDTVESGLYVSNVVSDAVLNGVVSAQEE------EFKEALAAKDSENFLLNKKIED 610
++ L +E L +++ +E+ + E ++ LL ++ E+
Sbjct: 11017 ERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREE 11076
Query: 611 LNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNE 790
+NH++ L++ + + + E +++++ + K L + +A+ E K + E
Sbjct: 11077 INHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEE----RKSLEETKARIIEMKTKAELQE 11132
Query: 791 MMHMVLEKDNIILSLHKQIELQSQNTQSLDCFR-RDEIEDQNIKEEIEKQIVE------- 946
+M E+D + + ++E + N + R R EI+ + K +K+I+E
Sbjct: 11133 IMQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLE 11192
Query: 947 ---TIYVTQIQELGEE---------------HDL--------------------LRLESA 1012
+ +TQ Q++ EE HD+ +RL+
Sbjct: 11193 KMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKE 11252
Query: 1013 KYQDEIQSLKDEC---------------HAKEMSKQAEISKLSHTLEESIMNSNLESLFT 1147
+ E Q + DE KEM + EI K TL+E + E
Sbjct: 11253 ELDIERQKIADEQGLVVQNKAKLQNENERIKEMDE--EIKKEKETLKEMEAHLRKEKEEM 11310
Query: 1148 AEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXX 1327
+ E T R + + ++ D+ +N L ++ D L E ++ +
Sbjct: 11311 RSVIEETQRRKKEDLEKMSTDVNKQNQ---DLMNQRDLLKQEREEINHKWTQLQQRID-- 11365
Query: 1328 XXXXXTLKASMEMQCSKLKDE-------LEEERGKISENLERISKLQKMNNE---LAERS 1477
+ Q SK K+E +EEER + E +I +++ E+
Sbjct: 11366 ---------EFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKE 11416
Query: 1478 KSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSV---IDKKEAEV 1648
K + + V + ++L D + ++K ++E+
Sbjct: 11417 KEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEI 11476
Query: 1649 SGHLDTISSLQTVLSN-------QKFEIEKSQKVLQSFESHIEKLVND---SLHEVD--- 1789
+ ++ L N ++ +IE S++++Q +E+ D E+D
Sbjct: 11477 MKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIER 11536
Query: 1790 --------------SAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQE--QHIE 1921
+ + N R + ++ ETL+ +++ + + + +
Sbjct: 11537 QKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQ 11596
Query: 1922 HQCKEELEGHIADLVLNDFSNDILSWS---RRKEEAVVHD--------DEFDAERIALLN 2068
+ KE+LE D+ N + D+++ +++ E + H DEFDA+
Sbjct: 11597 RRQKEDLEKMSTDV--NKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQ------ 11648
Query: 2069 ELKSLHQDL-ELLKAEEAVKSLSNN-VGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALR 2242
K +DL + K EE KSL + + + I++ K+ E +V ++
Sbjct: 11649 VSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMK 11708
Query: 2243 RHSTGQA------------FREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADA 2386
+ Q + +D E + +E +E K + E ++
Sbjct: 11709 KEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSEL 11768
Query: 2387 SDSPLRNWPKEQLLGHFKQSFAGL-----KREYELELQRKT-----EEIYDLKRLLLNEK 2536
+ + + ++ + + K+ L ++++E++ Q++ ++I D + LL+ K
Sbjct: 11769 ENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNK 11828
Query: 2537 NGLH------AXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKM--------L 2674
+ L + E+ EK +E K + EE +R K +
Sbjct: 11829 SELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSI-TEETRRQKEDLEKMSTHI 11887
Query: 2675 CVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGI 2854
K++L+S+ D L +E +E + K L +++ + + + Q+E L K E
Sbjct: 11888 NEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSK--QKEEDLPKEKEMKEDRK 11945
Query: 2855 TDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLV 3034
+ E ++ A E+ +EKE +EQE + +M +++ + K +L +
Sbjct: 11946 SLEETKANILEMKTKAEPEEIKKEKEKE----EEEQEMRVKVEMERKEIEQIKSQLERVR 12001
Query: 3035 GEENKEHKR---QIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKN 3205
E + E K+ ++E+ KE+ E + Q R+++EE++ LD+ +++ + K+
Sbjct: 12002 SEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQ---RQQMEEERSELDKKIKQTDLEKH 12058
Query: 3206 DIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXIS------------ 3349
DI+N ++ L E EK +++
Sbjct: 12059 DIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQQNENERIKE 12118
Query: 3350 ---------SNLDSMQLELRNYNEEL----------KNEIEKKSTDI-----------DL 3439
L M++ L+ EE+ K ++EK STDI DL
Sbjct: 12119 MDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDL 12178
Query: 3440 LIKEKEELNERLAYTQKAMEQKEAV----------------------------LVEKLFE 3535
L +E+EE+N +L Q+ +++ E ++E+
Sbjct: 12179 LKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNR 12238
Query: 3536 GEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTE 3715
++ +E QS + E +DLL +E D +K+ EELQ + DLE+ M E
Sbjct: 12239 KRTELEEIEVDQSQQNKNVETMKDLLE---KERKDTEKE----REELQKQADDLEMQMIE 12291
Query: 3716 TKFLKEKLLVSDENLKEKDLQLRAFEI 3796
KE++ + ++K L+ +A EI
Sbjct: 12292 HGD-KEEMSKRSLDEEKKLLEQKANEI 12317
Score = 90.5 bits (223), Expect = 5e-15
Identities = 236/1241 (19%), Positives = 467/1241 (37%), Gaps = 149/1241 (12%)
Frame = +2
Query: 539 EEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISER-DRLLKD 715
+ E ++ + +LN + ++LN +LE+ KEE L S R + LL+D
Sbjct: 12842 QAELQKGQLEMEMHQLMLNSERDELNGMRVNLEKQ---KEEFELMQQNLESRRPESLLED 12898
Query: 716 FIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQ----SLDC 883
+ EK +++ A + ++ N M + + I KQIE + + Q L+
Sbjct: 12899 ILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKI-----KQIEGEIKTKQIEMACLEE 12953
Query: 884 FRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSL-----KDE 1048
++ E+++Q E E Q ++Q EE ++ E +DEIQ L K++
Sbjct: 12954 LKQKELDEQKNMRECENQ--------ELQMRREELAKMKTEIDIERDEIQKLRKQYEKEK 13005
Query: 1049 CHAKEMS---KQAEISKLSHTLEESIMNSNLESL---------FTAEIYENTFRE---LG 1183
C +++ ++ E K+ ++ ++ ++SL A++ +N RE +
Sbjct: 13006 CELEQIKPDLQKREPEKIDAEVQHDEIHGGIDSLKEEREEIEKMKADL-QNKLREAENMR 13064
Query: 1184 DQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTL----- 1348
D + + ++++ K + I+ +A + S+ N LQ++ L
Sbjct: 13065 DIMKREKDELEKKEAEIEQMAVETEDNDSDKN-LQDEMMKIEAILKVTKKQKNYLEQMNE 13123
Query: 1349 -----KASMEMQCSKLKDELEEERGKISENLE-RISKLQKMNNELAERSKSQNSIXXXXX 1510
K +E C L+ E E K+ E E +SK++ ER + +I
Sbjct: 13124 NLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKME-------EREAERKTIERVMD 13176
Query: 1511 XXXXXXXXXXXXXXXVVNMAFGSK-----LEELTDQINIFNSVIDKKEAEVSGHLDTISS 1675
+VNM K LEE +++ S + + +E+ +
Sbjct: 13177 EMAEEHEKIKKEREELVNMEEEIKKQRRVLEESMNEMTKKKSELQHERSELYKQKQQLED 13236
Query: 1676 LQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGE 1855
+ + S K +++ + + I K + + ++ + +++ E
Sbjct: 13237 M--IASESKRDVDTERSRQDKEDEQILKREREEIADMKDQLLKEKEDVETTKERINREKE 13294
Query: 1856 TLRAFVKNIQNQVAVSQEQHIEHQ----CKEELEGHIADLVLNDFSNDILSWSRRKEEAV 2023
+ + +Q +E +E+Q K E++ + L D L R A+
Sbjct: 13295 HIEKMQSQLNDQ---KEEMDLENQKLLYMKTEIQ--VKTNALEKMMQD-LQKERENVNAL 13348
Query: 2024 VHDDEFDAERIALL---NELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEG 2194
V + + E+ +L N+ K H + E+ + E ++S+ + + I + ++
Sbjct: 13349 VIQHQKEREQRDILIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTR 13408
Query: 2195 KDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFE 2374
+ E ++ K + + RE E + E K E EK + +
Sbjct: 13409 SE-ELENLIKKQQKEFETKENEMQRERKALEKMNAEL-ERKSTELKNKIEKVTVWEADLQ 13466
Query: 2375 TADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKT-----EEIYDLKRLLLNEKN 2539
L+N + + +++ ++++E+E RKT E + L+ L +EK
Sbjct: 13467 KEKNKTEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKK 13526
Query: 2540 GLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLL 2719
+ + EI + E + +E K L + + L ++ L
Sbjct: 13527 SMLSRLSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKL 13586
Query: 2720 KEIKEKDSNSKVLA------EKLSDALKKSA--------------DHAQRESHLLKHIAD 2839
+EKDS ++ A EKL + ++K+ D ++E L AD
Sbjct: 13587 SIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRAD 13646
Query: 2840 LEAGI-----------TDREIMTSVCSD---------------------------VLTAL 2905
+E T++EI+ ++ L +
Sbjct: 13647 IERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEKQRKRNDLTLQELRKEKMALEQM 13706
Query: 2906 FVEMVREKEFSLSLATK---EQETVNQKQMSLRKMLEDKDKL-LCLVGEENKEHKRQ--- 3064
++ +EK+ SL + +Q + K+ L + ++ D L + L +N +K+Q
Sbjct: 13707 ITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEV 13766
Query: 3065 -IAILEKLKEETENNPGRVFLQSEERE------KIEEQKRVLD-------QALQECEELK 3202
+ I+E +K + + L E R+ E+QK VL Q E E+
Sbjct: 13767 DVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFT 13826
Query: 3203 NDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELR 3382
DI+ + ++ REE + LNK++ L S+ LE+
Sbjct: 13827 TDIKTEKEHVEKEREEIDVLNKEI---------------------IKSKEELQSLNLEI- 13864
Query: 3383 NYNEELKNEIEKKSTDIDLLIKEKEEL------NERLAYTQKAM------EQKEAVLVEK 3526
E K EI K I+ L + + +L + L T+K M ++ E L
Sbjct: 13865 ---EMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMN 13921
Query: 3527 LFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVA 3706
L + + ++ L ++ A + Q E + +L+ +E D+ S + L+ ++ +L
Sbjct: 13922 LQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKL 13981
Query: 3707 MTETKFLKEKLLVSDENL-----KEKDLQLRAFEIANSEKQ 3814
+ L EK+ E L KE+D +I SEKQ
Sbjct: 13982 ---SHVLNEKVQREQEELERLLEKERDDIENCKKIIESEKQ 14019
Score = 87.8 bits (216), Expect = 3e-14
Identities = 268/1329 (20%), Positives = 516/1329 (38%), Gaps = 159/1329 (11%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNT 451
+EVE+ D R E +ER +I D + L +N + + E+I+
Sbjct: 11516 VEVEEQRKDIRLQKEEL---DIERQKI--ADEQGLVVQNKAKLQNENERIKEMDEEIKKE 11570
Query: 452 KDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENF-------LLNKKIED 610
K+ L +E+ L +V+ Q+E+ ++ + +N LL ++ E+
Sbjct: 11571 KETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREE 11630
Query: 611 LNHKIWSLEETL--------QYKEEVILSSHETISERDRLLKDFI--------------- 721
+NHK L++ + + KEE + + ER L + I
Sbjct: 11631 INHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIK 11690
Query: 722 -----HEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCF 886
E+++M+ + + +++L +++ + E D+ L+ ++ Q + L+
Sbjct: 11691 KEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKM 11750
Query: 887 R-------------RDEIED------------QNIKEEIEKQIVETIYVT-QIQELGEEH 988
+ R E+E+ +N KE ++K +VE +IQ EE
Sbjct: 11751 KSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEEL 11810
Query: 989 DLLRLESAKYQDEIQSLKDEC-HAKEMSKQAE--ISKLSHTLEESIMNSNLESLFTAEIY 1159
D+ R + A QD + K E + E K I K TL+E E I
Sbjct: 11811 DIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSIT 11870
Query: 1160 ENTFRELGD------QISQLRNDMYSKNSYIDS-----------LASRIDFLSSECNKLQ 1288
E T R+ D I++ + D+ S+ ++ L RID ++ +K +
Sbjct: 11871 EETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQK 11930
Query: 1289 EQXXXXXXXXXXXXXXXXTLKAS-MEMQCSKLKDELEEERGKISENLERISKLQKMNNEL 1465
E+ KA+ +EM+ +E+++E+ K E E K++ E+
Sbjct: 11931 EEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEI 11990
Query: 1466 AERSKSQ-----NSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVID 1630
E+ KSQ + + + M S++ + Q+ S +D
Sbjct: 11991 -EQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMK--SEIMKQRQQMEEERSELD 12047
Query: 1631 KK-------EAEVSGHLDTISSLQTVLSNQKFEIEKSQKVL----QSFESHIEKLVNDSL 1777
KK + ++ + + L + QK EI+ ++ L Q + L+ + +
Sbjct: 12048 KKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKI 12107
Query: 1778 HEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIA 1957
+ + N R + ++ ETL+ N+Q + KEE+E I
Sbjct: 12108 EQQNE-----NERIKEMDEEIKKERETLKEMEVNLQKE-------------KEEIESVIE 12149
Query: 1958 DLV-----LNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAV 2122
+ L S DI + +K++ + D ER + ++L L Q ++ +
Sbjct: 12150 ETQRRKEDLEKMSTDI---NEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFET---- 12202
Query: 2123 KSLSNNVGVSTK---GIHYFSQLIQEGKDGEA--SDVQGKSRALRRHSTGQAFREPPKPE 2287
++N+ V+TK +L Q K+ E+ + K L Q+ +
Sbjct: 12203 ---TSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTELEEIEVDQSQQNKNVET 12259
Query: 2288 DLYTTYSEGKIVEPHPTEEKKL---LAILAFETADASDSPLRNWPKEQLLGHFKQSFA-- 2452
E K E E +K L + E D + R+ +E+ L K +
Sbjct: 12260 MKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILR 12319
Query: 2453 ---GLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVL 2623
L++E E ++ +K E+ L++ + N+KN + + E +K L
Sbjct: 12320 QRDDLEKEKE-DMMKKWNELDGLQKEIQNQKNEMEEIKCELETKRIEIIKE-----QKRL 12373
Query: 2624 QENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIK-EKDSNSKVLAEKLSDALKKSADH 2800
+E+ EE Q +++ V E+ Q +I+ + + K E+D +++A+ L D
Sbjct: 12374 EESLNTVNEERQYLEIVRVDYEKHQQQIEEMRVKTKMERDELDQLMAKMLMD-------- 12425
Query: 2801 AQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQK 2980
++E+ K D++ L EM + K F+L +E + QK
Sbjct: 12426 -RKENERSK--------------------DMIGLLKKEMEQTK-FNLDAQEEELKLEKQK 12463
Query: 2981 QMSLRKMLEDKDKLLCLVGEENKEHKRQ-----IAILEKLKEETENNPGRVFLQSE---- 3133
+ +K LE + E K K Q E LKEE + PG+ F+Q +
Sbjct: 12464 IQNEKKDLEMFKAEIKREASEVKTLKEQQLEKDTKAFEALKEE--HLPGQ-FVQQKGGEF 12520
Query: 3134 EREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSL-----REEQEKLNKQLRCMXXXXX 3298
ER +I+E KR+L + +E +EL+ + Q ++L ++ E+L+ L
Sbjct: 12521 ERIQIDEVKRILSEIHKEKKELERNKQILEHQREALLEIKSKQPSERLDVILVSSATQTS 12580
Query: 3299 XXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLA 3478
+ + D ++ + +E + EI+K D +K E + ++A
Sbjct: 12581 DLEDIPDVSASQGETVEKHTDIIKEYTTSIPKE-EYEIDKLKQQGDKKLKSTRE-DTKMA 12638
Query: 3479 YTQKAMEQK---EAVLVEKLFEGE--------------QKILLLESSQSATREQTEKYRD 3607
T+ + K + ++ KL G+ +++ + + + + +++ EK R
Sbjct: 12639 DTEVTTQYKYIPDPSIMMKLESGKDETDGLTEVHTTERRELEITKLALQSEQQEIEKIRQ 12698
Query: 3608 LL----NSLTEEHADLKKQF-------LSATEELQSKERDLEVAMTETKFLKEKLLVSDE 3754
+ N L + +DL+KQ+ + E E DLE + ETK +E+L +
Sbjct: 12699 DIDREKNDLEKYRSDLEKQYEEMEICKQNIENERAELEIDLENIIIETKSKQERLESIEV 12758
Query: 3755 NLKEKDLQL 3781
L+EK++Q+
Sbjct: 12759 QLQEKNVQM 12767
Score = 85.1 bits (209), Expect = 2e-13
Identities = 232/1247 (18%), Positives = 476/1247 (38%), Gaps = 81/1247 (6%)
Frame = +2
Query: 266 SFIEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIR 445
S I+V+ ++ + K + +E+M+ D N L+ D+ + + D++
Sbjct: 279 SAIQVQINEIEMKIGETQKAKDLMEQMKAEIEDEKNELEKKKEDIKRQRDQFEQIKLDLQ 338
Query: 446 NTKDLLD-----TVESGLY------------------VSNVVSDAVLNGVVSAQEEEFKE 556
K ++ T + GL + V + N S QE
Sbjct: 339 QVKMEMEQRWHETEKEGLEQRAVIQREKEQLKYLQDEIQRVREEVERNREFSKQEHARIS 398
Query: 557 ALAAKD-SENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEKD 733
L A+ EN L+ K D+ K LEE K E+ ER R ++ + +
Sbjct: 399 QLRAQALEENNLIENKWHDILRKEKDLEEM---KHEI---------ERGR--EELVMNGE 444
Query: 734 LMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQN 913
L+++ ++ EQ + M+ M D I + ++++ + D + + + +
Sbjct: 445 LVKKEWEKIEQAKVDIQSHMISMEGRVDEIKRETERLKHIKTEMQRDKDALEKQKDDTRK 504
Query: 914 IKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKL 1093
KEE E++ E VT+ E R E + E+Q + D AK + ++ E ++
Sbjct: 505 AKEEAERKRYEI--VTEELEHRARLQRERDELENIRAEMQRVNDVEKAKILKEKEESIRI 562
Query: 1094 SHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSE 1273
EE+ L AEI R Q LR + ++L ++ + +S+
Sbjct: 563 R---EEARQERETTELVNAEIKAEKERLNQRQEEMLRERQEIERIKHETLRAKEEIENSQ 619
Query: 1274 CNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSK-----LKDELEEERGKISENLERIS 1438
++E K E+Q +K K ELEEER E+LER
Sbjct: 620 DVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKEQMEEAKVELEEER----EDLER-- 673
Query: 1439 KLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEEL-TDQINIF 1615
K ++ E+ + +N I V S+ E T+++ +
Sbjct: 674 KRDLVSREIEQAEFLRNEILR-------------------VKEEMESRWRETETEEVEL- 713
Query: 1616 NSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSA 1795
A+ L+ + L+ + IE+S+ L ++ ++KL + +
Sbjct: 714 -------RAKTQHELERLEKLREETERSQKNIEESKIELMLWKESLDKLKGEMEEDKHVV 766
Query: 1796 FCSLNSRFYSLIHKVDNSGETLRAFVKNIQ---NQVAVSQEQHIE-----HQCKEELEGH 1951
+N + E L ++ ++ ++ +S+E+ E ++ + EL+
Sbjct: 767 IMQMN--------EAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQ 818
Query: 1952 IADLVLNDFSNDILSWSRRKEEA-----VVHDDEFDAERIALLNELKSLHQDLELLKAEE 2116
A++ D+ + ++ KEEA VH+ E ++ +E + E L+ +
Sbjct: 819 HAEM--EDWFRVV---NKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRD 873
Query: 2117 AVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLY 2296
++ + + K I Q +++ + E +Q + L + F E + E L
Sbjct: 874 EIQKKAEELEQINKEIQRARQELEKMRYFEKESLQ---KMLEDTQQERVFVEQVRSELLK 930
Query: 2297 TTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYEL 2476
+ K + +E K+L + + D R + E + +QS
Sbjct: 931 NKADQDKCLFEMDSERKELEQMRFQVENEKKDLEQRRY--EMMRYDVEQS---------A 979
Query: 2477 ELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEV 2656
++QR+ EE+ +K L+ + ++ I E+ NK L E
Sbjct: 980 QVQRQKEELEKIKSQLVIDTESMNRSRELARQDREKAELLIVEIQEQREDVNKRLE-ETK 1038
Query: 2657 QRYKMLCVLKEELQSKIDSLLK-------------EIKEKDSNSKVLAEKLSDALKKSAD 2797
QR + L +L+++++++ + L K E+KE+ + + E+L D +K D
Sbjct: 1039 QREEALRLLRKDMENEREDLEKIRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKG-D 1097
Query: 2798 HAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKE---FSLSLATKEQET 2968
+RE + H + E I E M ++ + VE+ ++KE + A E
Sbjct: 1098 QEEREK--INH--EKEEMIRKMEAMKREMGEI-EDMKVELTKQKENIDMKMEHARLEMTN 1152
Query: 2969 VNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKI 3148
+ + L + ED + + E ++ + + K KE+ E ++ L E EK+
Sbjct: 1153 LEMMKADLLRQKEDIENQMLAAKSERQQMEVMRTEILKQKEDVER---KMELAKAEMEKM 1209
Query: 3149 EEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXX 3328
+ K + + +E EE + + +++ ++ E E K+L
Sbjct: 1210 QHVKDEIQKQRKELEERMQKTKREIGEMELMKREMEGKKKELDQRMKLTMRKKEEMERLK 1269
Query: 3329 XXXXXISSNLDSMQLELRNYN---EELKNEIEKKSTDIDLLIKE------KEELNERLAY 3481
+++ ++E E++K EI++ + +L ++E KE++N +
Sbjct: 1270 MEIQRAKDDMEFKRVETERQKYEMEQVKAEIQRAREEFELRVEERDLEEEKEQMNLTIIN 1329
Query: 3482 TQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEK-------------YRDLLNSL 3622
+ +E ++ + F+ E + + SQ T +Q E R++L L
Sbjct: 1330 LIQQIEATREMVHKTKFQFENR---MAGSQMGTADQEEMNAEMQRLILEIEHIREMLRGL 1386
Query: 3623 TEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLK 3763
E K+ EE++ + +++ E ++ +EK++ + L+
Sbjct: 1387 KGEVEQNKEIMKRDREEIRLLKIEVQRRRREIEYREEKIMREQDELE 1433
Score = 84.0 bits (206), Expect = 5e-13
Identities = 228/1214 (18%), Positives = 473/1214 (38%), Gaps = 129/1214 (10%)
Frame = +2
Query: 527 VSAQEEEFKEALAAKDSENFLLNKKIEDLNHK---IWSLEETLQYKE---------EVIL 670
+ ++E+ ++ L A +EN LN++ + L+ K + S + L+YK+ +V
Sbjct: 1591 LQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSEKSKLEYKKPLEIKQVDAQVQT 1650
Query: 671 SSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASR----DNEMMHMVLEKDNIIL--- 829
E SE D L I E D +Q + +Q+L ++ + +M + L +D + L
Sbjct: 1651 ELMEDASEYDMALS--IEELDKQRQFLEYFKQELLAQKCTMERQMAEIELSRDELSLREA 1708
Query: 830 ----------SLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELG 979
+ Q+ELQ Q + +DE+E K E++K V+ TQI E
Sbjct: 1709 TLQTATQTTADMELQLELQKQELEQT----KDEME--RTKLEVQKGWVDL--QTQIAESR 1760
Query: 980 EEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAE-- 1153
E+ +++R+E K +D + ++ + ++ + +A+ L TL + N + +
Sbjct: 1761 EKEEMVRIELEKARDVLNRIRQDVETEKQTMEAD---LKFTLAKEFENLEAQRKMMEDEK 1817
Query: 1154 -IYENTFRELGDQ---ISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXX 1321
EN EL + I + +++M+ + +++ A ++ E K +
Sbjct: 1818 RALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERS 1877
Query: 1322 XXXXXXXTLKASMEMQCSKLK-----------------DELEEERGKISENLERISKLQK 1450
L+ E+ +++K DE+E E+ KI + ++Q
Sbjct: 1878 REIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQT 1937
Query: 1451 -MNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMA-----------------FG 1576
+N + E QN++ V +M
Sbjct: 1938 DLNRQQKEMQDIQNAVFMEKSELKKSQDEIAEQLKQVGDMMQFTQNEKDNLDRERAAIIE 1997
Query: 1577 SKLEELTDQINIFNSVID-----KKEA------------EVSGHLDTISSLQTVLSNQKF 1705
KL+ D ++ N ++ KKE + + + ++ L +K
Sbjct: 1998 QKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKE 2057
Query: 1706 EIE-----------KSQKVLQSFESHIEKLVNDSLHE---VDSAFCSL---NSRFYSLIH 1834
E++ K + VLQ+ EKL D+L E ++ A L ++
Sbjct: 2058 EMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAE 2117
Query: 1835 KVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSN--DILSWSRR 2008
+ E + I+ Q ++ + Q + + + V D N D+ ++
Sbjct: 2118 ETKRKREDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQK 2177
Query: 2009 KEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQ--- 2179
+ + + E +R L+E++ + D E + E L + FS+
Sbjct: 2178 ERQYMDRLVEEIEKRTKALDEMQ-MEVDKERQEVESKRDELEQETSKLREDEDEFSRQKE 2236
Query: 2180 ---LIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKK 2350
+IQ E+ +++ +S + + T F + L +E K + + K
Sbjct: 2237 KNNIIQAEIQKESDNLELQSENISKERT--IFELEKEHLGLRENEAEYKQKQIDELQNKL 2294
Query: 2351 LLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLN 2530
+ + E A R + +++ A ++ E+E R+ E + ++ +N
Sbjct: 2295 RMEKVQVEQMQADKDQQRKKAEYVKTARGRETTALEEQRQEMESLREEYENVEKQKKHVN 2354
Query: 2531 EKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYK-MLCVLKEELQSKI 2707
E+ L + + + EN E +++YK L E+LQ +
Sbjct: 2355 EQKEL-----------------FESRMKSLEMEN-----EAMKKYKEKLDKEYEDLQFQR 2392
Query: 2708 DSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDR-------E 2866
KEI++ + ++ AE + + KK + + + ++ + + + ++ E
Sbjct: 2393 QLFEKEIQQMRTELQIEAENI-ERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDE 2451
Query: 2867 IMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLC--LVGE 3040
+ + +D+ VE + ++L ++E+ +K+ K+ E++ + L +
Sbjct: 2452 VRKKINADLSE---VEKQKSALVQMNLKISQEESYVKKEKDRLKLQENEQNMQMSQLNAK 2508
Query: 3041 ENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNK 3220
+N+ +RQ A +EK K E EN R+ E+EK+E + + Q E++N+++ K
Sbjct: 2509 QNELDERQ-AEMEKQKRELENVMDRL-----EKEKVE-----ITKEKQRVNEMQNEVKRK 2557
Query: 3221 HSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEE- 3397
++ +D ++ QE L +Q I ++ + + EL E+
Sbjct: 2558 NASVDLIK--QEVLREQ----------------------DHIENSREILNRELEKIKEKK 2593
Query: 3398 --LKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAV---LVEKLFEGEQKILLLE 3562
L E E +++ KE + L + A QK E E + E+ ++ L+
Sbjct: 2594 TILAEEFEALDDKKEMIGKEMQRLGKMKAELQKEAEDTEKQRRDIDNDRRNNEEMVIKLQ 2653
Query: 3563 SSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKER-DLEVAMTETKFLKEKL 3739
+ + T++ RD E + ++KQ L + + KER DLE TE K L+++L
Sbjct: 2654 NEKKDIETSTDRIRD-----EEANLRVQKQRLESDRDTLEKERFDLEKTKTEMKDLEKQL 2708
Query: 3740 LVSDENLKEKDLQL 3781
+ ++ ++QL
Sbjct: 2709 ---ESQSRQHEIQL 2719
Score = 83.2 bits (204), Expect = 8e-13
Identities = 212/1227 (17%), Positives = 466/1227 (37%), Gaps = 63/1227 (5%)
Frame = +2
Query: 320 KIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGLYVSNV 499
+I L+ + DT N + +L +D + ++++ +++ + + L +
Sbjct: 7403 QIRAELQNKQRDMDDTTNIMMKEKAELARDLENLQNEKDELQKSRENIQKLMKELQEERL 7462
Query: 500 VSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSH 679
+ LN + ++F E + K N ++++ +I + L +E+I
Sbjct: 7463 KTSEALN----KERQQFTEEIKLK-------NDSLDEIQAEIDRQKRALVTDKEIITKQM 7511
Query: 680 ETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMV--LEKD-NIILSLHKQIE 850
+ + + + E D+ + Q + L E++ LE++ + +L + +E
Sbjct: 7512 MDLQKTQDVRRQS-DESDIARANLQRERESLDQLSVEILKQKQDLERERDELLEQWRLVE 7570
Query: 851 LQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEI 1030
Q + +++ + + ++++ E+I KQ+ + + +L +L L K
Sbjct: 7571 TQKMDNENVKQLKTELLDEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNLQK----- 7625
Query: 1031 QSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRND 1210
Q ++DE +A++ ++ L+ + ++E +YE + ++ +++
Sbjct: 7626 QGIQDE--------RAQLERMKGELQ--MKADDIERKMQEILYEK------QKYAERKSE 7669
Query: 1211 MYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDE 1390
Y +Y+D + + L+ E + E K +E+ ++ + E
Sbjct: 7670 NYKIQTYLDEANAEVQKLNKELERYDENLE----------------KCKLELDKARAETE 7713
Query: 1391 LEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMA 1570
++ KI E + LQK + +
Sbjct: 7714 RVKQGAKIPETQQIEQSLQKERDYI----------------------------------- 7738
Query: 1571 FGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESH 1750
E++ + I+K +AE+ + +Q + QK E+ K QK+ E
Sbjct: 7739 -----EDIRRNLFKKEEAIEKDKAEIRLRHQELDLIQAKVVKQKEEMVK-QKIESEREIQ 7792
Query: 1751 IEKL-VNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQ 1927
EK + S E++ + L D + + R V N QVA +
Sbjct: 7793 QEKKKLQRSEEELEDKMQKIKREMIELKLLQDET-DGKRKDVDNKMRQVA---------R 7842
Query: 1928 CKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLK 2107
++ELE AD+ + S + +++ + + ERI ++ + H
Sbjct: 7843 KRDELEKMKADV-------ESASKKLEVDRVMLNTERDELERIKTESQRATEHMQSH--- 7892
Query: 2108 AEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPE 2287
AEE L V+T+ +LIQE + K R + E
Sbjct: 7893 AEERAGDLGEKEPVNTR----IQRLIQEAEKASKMAWSTKHEPEMRMQREVSVEEESVER 7948
Query: 2288 DLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKRE 2467
+ + I+E E + A S L N E L K++ +
Sbjct: 7949 QDMSANMQRMILEIEHARETLRGMKDEVQAARKERSELENMKLEFLT--MKKNMEKTYEQ 8006
Query: 2468 YELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPV 2647
E+Q++ ++I K LL E+N L + +K+L EN+LL
Sbjct: 8007 QNDEIQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMALDK----QKLLAENELLER 8062
Query: 2648 EEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLK 2827
E+ K++ E L+S + +E A + + A ++ ++ ++ L
Sbjct: 8063 EKADVIKII----ENLESLREEATRE----------RATETAQATRRDSEELMQKMEALS 8108
Query: 2828 HIADLEAGITDREIMTSVCSDVLTALFVEMVREK-EFSLSLATKEQETVNQKQMSLRKML 3004
+ D + ++ + D L L ++++++ E + A +Q+ + ++ +
Sbjct: 8109 -MEDFQEASKNQMVELKRQIDKLIELKADLLQQQTELKKTKADLKQQMDDLEKTRSEILK 8167
Query: 3005 EDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEE----REKIEEQKRVLD 3172
+KD ++K + ++ +++ K++ E ++ L+ + R +I +K+ LD
Sbjct: 8168 HEKDT-------DSKTRELELIEIQRQKDDLETRIQKLTLEKRDLEVLRSEIVLEKKDLD 8220
Query: 3173 QALQ-------ECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXX 3331
Q ++ E E++++DI N +I+ R+E E L ++
Sbjct: 8221 QKMKQVIRKRDEMEKIRSDIANATEEINRERQELEILRNNVQ-SARHDFELLLERTANLE 8279
Query: 3332 XXXXISSNLDSMQLE-------LRNYNEELKNEIEKKSTDIDLLIKEKEELN-------- 3466
+++++ + LE +RN E++ +EK +ID K E+
Sbjct: 8280 DEESAATDIERLVLEVVKIREMVRNLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDIGQ 8339
Query: 3467 ------------ERLAYTQKAMEQKEAVLVEKLFEGE----------QKILLLESSQSAT 3580
E+ ++ +E+ A L EK E E +++ L+ +
Sbjct: 8340 IRENLGGLGEEIEKTRRDKRELEKMRAELAEKQQEQESMREMLHKEREELEQLKDEINRE 8399
Query: 3581 REQTEKYRDLLNSLTE-----EHADL---KKQFLSATEELQSKERDLEVAMTETKFLKEK 3736
+E E R+L+ ++ + E D+ K++ S TEEL +K+RDL+ ++ + L++
Sbjct: 8400 KEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQT 8459
Query: 3737 L--LVSDENLKEKDLQLRAFEIANSEK 3811
+ + K +L+ FE+ E+
Sbjct: 8460 IEEINIQHGKKRAELEGIGFELKKGEQ 8486
Score = 73.9 bits (180), Expect = 5e-10
Identities = 215/1271 (16%), Positives = 497/1271 (39%), Gaps = 103/1271 (8%)
Frame = +2
Query: 296 DTRKSLETKI---AETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLD 466
+ K ++T + A+ +E++++ ++ + ++ + L+E+I+ +D++D
Sbjct: 6746 EAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIKKKRDIID 6805
Query: 467 TVESGLYVSNVVSDAVLNGVVSAQEEEFKE------ALAAKDSENFLLNKKIEDLNHKIW 628
+ + ++ + + A+ + FK+ ALA + L K ++++
Sbjct: 6806 ESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQQKRNALEKMSKEISRDRM 6865
Query: 629 SLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVL 808
LE+ K+E+ L+ E +R+ D QR QE + L S +
Sbjct: 6866 KLEDE---KKEIQLAREEL----ERMHGDM--------QRQQEAKDHLLSG--------I 6902
Query: 809 EKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEH 988
++++ +I LQ R+ EI D + + ++V Q+ E+ +
Sbjct: 6903 TDESLLKKSEAEIVLQPSQVDKAKPARKTEISDSD---------KQPVFVQQMPEM-DLK 6952
Query: 989 DLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESL--FTAEIYE 1162
D L+ + + ++ +KD + K LE+ ++ ++ L AE+ +
Sbjct: 6953 DALKKDFESEKLDLPKVKDVLPQDQQMK----------LEQKLIEDEMDKLKQMRAELQK 7002
Query: 1163 NTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXX 1342
DQI + + DM ++ +D +A+R+ +L E+
Sbjct: 7003 EA-----DQIEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINIQ------------ 7045
Query: 1343 TLKASMEMQCSKLKDELEEERGKISENLERI-SKLQKMNNELAERSKSQNSIXXXXXXXX 1519
K + + Q + + E + ERI +++ + N ELA++ +
Sbjct: 7046 --KVNQQKQATAFQME--------KTDFERIKTEIDQANKELADQQE------------- 7082
Query: 1520 XXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQ 1699
K ++ ++ +++ A +S ++TI++ LS++
Sbjct: 7083 --------------------KNKKTITEMQKERETLEEMRANISKQVETITNENKSLSSR 7122
Query: 1700 KFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYS---LIHKVDNSGETLRAF 1870
+ E+ K Q+ + + +++L N + E+ C L+ R L +VD+ + +
Sbjct: 7123 ESELAKLQEDILQQQQEMDELKNTIMMEM----CQLDQRQSDIDLLQKEVDDLMDFTKTE 7178
Query: 1871 VKNIQNQ--VAVSQEQHIEHQCKE-ELEGHIAD---LVLNDFSNDILSWSRRKEEAVVHD 2032
+ N++ + ++Q ++I+ ++E + L LN+ D++ + +E +
Sbjct: 7179 MANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNE-EKDLIE--KERELLTKNL 7235
Query: 2033 DEFDAERIALLNELKSLHQDLELLKAEEA-VKSLSNNVGVSTKGIHYFSQLIQEGK---- 2197
D D +++ + EL++L + E +K E+ ++ + ++ G FS+ ++ +
Sbjct: 7236 DHTDKDKMDMKRELENLKVEKETIKNEKKELEKMKISLQRKAIGFKEFSEKTKDERPIVE 7295
Query: 2198 ----------DGEASDVQGKSRALRRHSTGQAFREPPKPEDLYT-------------TYS 2308
D +GK R T + R+ EDL+ Y
Sbjct: 7296 EMAAQFTRQLDISERPAEGKFIEERLDQTEKKRRKTYYTEDLFQEEKTDLQKTKEEINYD 7355
Query: 2309 EGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQR 2488
+I K+ + T++ + KE++ + + + ELQ
Sbjct: 7356 REEIYRQRTELNKEKETLKQMHTSNLKEIENIEKEKEKIQRTWNEL-----DQIRAELQN 7410
Query: 2489 KTEEIYDLKRLLLNEKNGL--HAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQR 2662
K ++ D +++ EK L E K K LQE +L E + +
Sbjct: 7411 KQRDMDDTTNIMMKEKAELARDLENLQNEKDELQKSRENIQKLMKELQEERLKTSEALNK 7470
Query: 2663 YKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLA-------------EKLSDALKKSAD-- 2797
+ EE++ K DSL + E D + L +K D ++S +
Sbjct: 7471 ERQQ--FTEEIKLKNDSLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDVRRQSDESD 7528
Query: 2798 ------HAQRES------HLLKHIADLEAGITD-----REIMTS-VCSDVLTALFVEMVR 2923
+RES +LK DLE + R + T + ++ + L E++
Sbjct: 7529 IARANLQRERESLDQLSVEILKQKQDLERERDELLEQWRLVETQKMDNENVKQLKTELLD 7588
Query: 2924 EKEFSLSLATKEQET---VNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEE 3094
EKE + + + ++ + + +++L K LE+ + + +E + +R L+ ++
Sbjct: 7589 EKESTEKIRKQLEQDKAYMEENKLNLHKELEELNLQKQGIQDERAQLERMKGELQMKADD 7648
Query: 3095 TENNPGRVFLQSEE-REKIEEQKRV---LDQALQECEELKNDIQNKHSDIDSLREEQEKL 3262
E + + ++ E+ E ++ LD+A E ++L +++ +++ + E +K
Sbjct: 7649 IERKMQEILYEKQKYAERKSENYKIQTYLDEANAEVQKLNKELERYDENLEKCKLELDKA 7708
Query: 3263 NKQLR-----CMXXXXXXXXXXXXXXXXXXXXISSNL-------DSMQLELRNYNEELKN 3406
+ I NL + + E+R ++EL
Sbjct: 7709 RAETERVKQGAKIPETQQIEQSLQKERDYIEDIRRNLFKKEEAIEKDKAEIRLRHQELDL 7768
Query: 3407 EIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATRE 3586
K + ++K+K E + +K +++ E L +K+ + +++++ L+ Q T
Sbjct: 7769 IQAKVVKQKEEMVKQKIESEREIQQEKKKLQRSEEELEDKMQKIKREMIELKLLQDETDG 7828
Query: 3587 QTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKE 3766
+ + + + + + +L+K + A E SK+ +++ M T+ + + + ++
Sbjct: 7829 KRKDVDNKMRQVARKRDELEK--MKADVESASKKLEVDRVMLNTERDELERIKTESQRAT 7886
Query: 3767 KDLQLRAFEIA 3799
+ +Q A E A
Sbjct: 7887 EHMQSHAEERA 7897
Score = 70.9 bits (172), Expect = 4e-09
Identities = 202/1162 (17%), Positives = 457/1162 (39%), Gaps = 73/1162 (6%)
Frame = +2
Query: 527 VSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVI------------- 667
+ EEF+ + +D L ++ E +N I +L + ++ E++
Sbjct: 1300 IQRAREEFELRVEERD-----LEEEKEQMNLTIINLIQQIEATREMVHKTKFQFENRMAG 1354
Query: 668 -----LSSHETISERDRLLKDFIHEKDLMQQRAQETEQ--KLASRDNEMMHMVLEKDNII 826
E +E RL+ + H +++++ E EQ ++ RD E + ++ + +
Sbjct: 1355 SQMGTADQEEMNAEMQRLILEIEHIREMLRGLKGEVEQNKEIMKRDREEIRLLKIE---V 1411
Query: 827 LSLHKQIELQSQNTQSLDCFRRDEIE-----DQNIKEEIEKQIVETIYVTQIQELGEEHD 991
++IE + + +DE+E Q +EE+E+++ E I +E+D
Sbjct: 1412 QRRRREIEYREEKIMR----EQDELELMSKMGQRQREELEERLEEVI---------KEND 1458
Query: 992 LLRLESAKYQDEIQSLKDECHAKE-MSKQAEISKLSHTLEESIMNSNLESLFTAE----- 1153
R+E + +D +LKD AKE + +Q E+ + + E T E
Sbjct: 1459 --RVEQMR-EDVNNALKDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAIK 1515
Query: 1154 IYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXX 1333
Y + EL I + R ++ I ++ + + ++
Sbjct: 1516 SYRASDLELSASIQKERQELEHYKEIILKEKHELNKIKEDVKAVKNDAEERMIKLHEEEK 1575
Query: 1334 XXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXX 1513
T + S++ +L+ E E+ N + + + N +L ER + +
Sbjct: 1576 EMKTKRVSLQNWERQLQTEKEK-------NQKGLDAIWNENQQLNERKQQLDIKELHLQS 1628
Query: 1514 XXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSV--IDKKEAEVSGHLDTISSLQTV 1687
V+ ++L E + ++ S+ +DK+ + + + +
Sbjct: 1629 EKSKLEYKKPLEIKQVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCT 1688
Query: 1688 LSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRA 1867
+ Q EIE S+ L E+ ++ + L + L D T
Sbjct: 1689 MERQMAEIELSRDELSLREATLQTATQTTA----DMELQLELQKQELEQTKDEMERTKLE 1744
Query: 1868 FVK---NIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHD-- 2032
K ++Q Q+A S+E+ E + ELE A VLN D+ + + E +
Sbjct: 1745 VQKGWVDLQTQIAESREK--EEMVRIELEK--ARDVLNRIRQDVETEKQTMEADLKFTLA 1800
Query: 2033 ---DEFDAERIALLNELKSL-HQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQ---E 2191
+ +A+R + +E ++L + EL + ++ +N+ + + +++ ++ E
Sbjct: 1801 KEFENLEAQRKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWE 1860
Query: 2192 GKDGEASDVQG----KSRALR-----RHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEE 2344
+ + D+Q +SR ++ R + D+ SE + E
Sbjct: 1861 ELEKKRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIEN 1920
Query: 2345 KKLLAILAFETADASDSPLRNWPKEQ--LLGHFKQSFAGLKREYELELQRKTEEIYDLKR 2518
+K + + L KE + + LK+ + E+ + +++ D+ +
Sbjct: 1921 EKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQD-EIAEQLKQVGDMMQ 1979
Query: 2519 LLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQ 2698
NEK+ L ++T + L+ KL+ E + ++L E+ +
Sbjct: 1980 FTQNEKDNLDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLL----EDCR 2035
Query: 2699 SKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDR-EIMT 2875
SL++++++ + K+ E+ + ++ E L+ + A T++ I T
Sbjct: 2036 I---SLMRDMQDLEQ-MKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDT 2091
Query: 2876 SVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEH 3055
L VE+ +E++ +++A E +K+ + K+ +K + +
Sbjct: 2092 LAEKQKLEDAAVELQKERDEIMNIA----EETKRKREDVDKIRVGIEKQEITFKDLKADL 2147
Query: 3056 KRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECE-------ELKNDIQ 3214
+++ AI+E ++ + + V + +I+++++ +D+ ++E E E++ ++
Sbjct: 2148 QKEAAIVENQRQAVQKDIQNV---KDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVD 2204
Query: 3215 NKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNE 3394
+ +++S R+E E+ +LR I D+++L+ N ++
Sbjct: 2205 KERQEVESKRDELEQETSKLR---EDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISK 2261
Query: 3395 EL------KNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILL 3556
E K + + + + K+ +EL +L + +EQ +A ++ +K
Sbjct: 2262 ERTIFELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQ----RKKAEY 2317
Query: 3557 LESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEE---LQSKERDLEVAMTETKFL 3727
+++++ E+ R + SL EE+ +++KQ E+ +S+ + LE+ K
Sbjct: 2318 VKTARGRETTALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKY 2377
Query: 3728 KEKLLVSDENLKEKDLQLRAFE 3793
KEKL D+ ++ Q + FE
Sbjct: 2378 KEKL---DKEYEDLQFQRQLFE 2396
Score = 63.5 bits (153), Expect = 7e-07
Identities = 89/436 (20%), Positives = 190/436 (43%), Gaps = 38/436 (8%)
Frame = +2
Query: 2588 VAEITGKFEKVLQENKLLPVEEVQRYKMLCVLK----EELQSKIDSLLKE--------IK 2731
V ++ +QE + + +E+V R K + ++ E+ +S I ++E +K
Sbjct: 14521 VTKLEDTLTSEVQEMRDMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEETLK 14580
Query: 2732 EKDSNSKVLAEKLSDA--LKKSADHAQRESHLL-----KHIADLEAGIT----DREIMTS 2878
EK N + L + L D L + D +E + ++IA LE I D+E +
Sbjct: 14581 EKSRNEETLLQLLHDKDDLSNTLDEKSKEIENITVTFKRNIAQLETTIAMMKKDKE---N 14637
Query: 2879 VCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHK 3058
+ +++L E RE + + E+E ++K ++ + LED +E K+
Sbjct: 14638 IENELLQLKQTEQEREIQRGTDDTSNERENYDEK-VTYKTELEDS--------KEKKKPD 14688
Query: 3059 RQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHS---D 3229
R + L+ ++ G Q+ E K+++ ++ D Q+ EEL ++++NK +
Sbjct: 14689 RDSS-LKLTDADSAKTDGEREAQTLET-KVQDVLQLTDYTTQDQEELHDEMENKMKIILE 14746
Query: 3230 IDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNE----- 3394
++ +++ +KL ++ R + S + S+ E+ + +
Sbjct: 14747 LNEAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEM 14806
Query: 3395 ---ELKNEIEKKST----DIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKIL 3553
E+K +I+ +S + D+ I++ +E E + K E++ + K + +
Sbjct: 14807 QQIEIKMQIQTRSVATQWETDVQIQQGQEATETTGHITKKSEEEISAKKTK----QPTVT 14862
Query: 3554 LLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKE 3733
LE + ++ + ++ RD LN E+ A +K ++L+ + D++ M E + E
Sbjct: 14863 KLEDTLTS---EVQEMRDSLNKEMEDVARMKTIMKMEKDQLEQAKSDIQTQMEEFERNME 14919
Query: 3734 KLLVSDENLKEKDLQL 3781
+ + +EK LQL
Sbjct: 14920 EAMEEKSRNEEKLLQL 14935
>ref|XP_001579764.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121913974|gb|EAY18778.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 3369
Score = 144 bits (364), Expect = 2e-31
Identities = 263/1257 (20%), Positives = 520/1257 (41%), Gaps = 84/1257 (6%)
Frame = +2
Query: 296 DTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDL-LDTV 472
D ++ ++ K + E I N LK +D ++ I KD ++ +
Sbjct: 1371 DLQEEIKEKSVQNEENSRI-----INDLKEFIKQYDEDIKSKDEKIKSIEQEKDAKINEI 1425
Query: 473 ESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQY 652
++ L + + + E + L+++DSE + L +I +L+ +L
Sbjct: 1426 KAELETKETENSQLFGNI-----SELQNMLSSRDSEYETVCSDNNKLKQEIEALKSSLSE 1480
Query: 653 KEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILS 832
KE S +S+ D + + E + + ++ +E +Q++ ++NE+ ++ E +N+ S
Sbjct: 1481 KENDFAS---ILSKYDEEVSNHNKEVEELTKKDEENKQQVDEKENEISNLKKEIENLKSS 1537
Query: 833 LHKQIELQSQNTQSLDCFRRDEIE-----DQNIKEEIEKQIVETIYVTQIQELGEEHDLL 997
L+++ SQN+Q++D + E D+++K++ E+ + ++ ++++ EE
Sbjct: 1538 LNEKDNEISQNSQAIDDSSKHVQELQHQFDEDLKQKQEEISAKDEELSNLKKVLEEEKSE 1597
Query: 998 RLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSN-------LESLFTAEI 1156
S + +DE+ K+E + S E K+ +L+ + + N E + EI
Sbjct: 1598 ITSSLQEKDELIKQKEEEISNLNSVIQEKEKVIASLQGKVNDENNEVNAKEAEIVSLNEI 1657
Query: 1157 YENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXX 1336
+ E+ +L + + K I L S I+ E + LQE+
Sbjct: 1658 QKKKEEEISSLQEKLNSTIAEKEKEISELQSSINDKDKEISSLQEK----VNIENNDVNT 1713
Query: 1337 XXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXX 1516
T +S+ Q + +E+ + +I E E +SKLQ + NE + S
Sbjct: 1714 KETEISSLNDQLKQKDEEINNLKSEIKEKFEELSKLQSLVNENEQVIVSLQEKVNSDEIN 1773
Query: 1517 XXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTI--------S 1672
+N + K +E++ FN+ + +K+ E+S + S
Sbjct: 1774 KENELKMKEEEISNLNGSIQEKEKEISLLKENFNNSLAQKDEEISNLKKVLEEEKSGITS 1833
Query: 1673 SLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSG 1852
SLQ +S + EI++ ++ + E I+ L N+ L + +N L K++ S
Sbjct: 1834 SLQEQISKLQSEIKERDEIQKKKEEEIQTLSNEKLELLKQKEEEIN----VLNSKLNESV 1889
Query: 1853 ETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHD 2032
E L+ + +N +S+ + + + EL+ I N N++ S KEE +
Sbjct: 1890 ELLKQKEGDNENNDKISEIRQQKEKEISELQSEI-----NSLKNEL---SANKEEMEKLN 1941
Query: 2033 DEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVG-VSTKGIHYFSQLIQEG----K 2197
+ E+ S+ Q + K+E V S+SN + + K + + I+EG K
Sbjct: 1942 ETIKERD----EEISSIKQKADDDKSE--VNSISNILSDIKQKLSNQTQESIKEGRVFSK 1995
Query: 2198 DGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFET 2377
+ E D + L E K ++ E E + T + + ET
Sbjct: 1996 EREVPDEETNISQLDYSPIKSKPSEVVKSREVIELVDED---EGNETNDIRSTVEYLSET 2052
Query: 2378 ADASDSPLRNWPKE--------QLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNE 2533
D + + KE Q L + Q L E+E+ +K++ + ++N+
Sbjct: 2053 IDEMQANIEELKKENAKKSQEKQSLIYQNQQLRILLDSAEIEMNKKSQGM----MTMMND 2108
Query: 2534 KNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLC--------VLKE 2689
KNGL + +I + +Q+ K +E+QR L +++
Sbjct: 2109 KNGLIENLTKELQTTRSQLNDIKQQAVYQMQQQKSFDDQEIQRLNGLISQKLSENEQMRQ 2168
Query: 2690 ELQSKIDSLLKEIKEKDS--------NSKVLAEKLSDALKKSADHAQRESHLLKHIADLE 2845
+ + D++ K I+EKD +K+L EKL++ + E L + +L
Sbjct: 2169 QFNLQADAMNKTIQEKDEMINQIKTRANKLLNEKLNENSNLQNLQKENEEKLSQKENELN 2228
Query: 2846 AGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLL 3025
+ + ++AL + ++ ++ K+QE + Q +++ E ++ L
Sbjct: 2229 QIKSQLNTVIQNAQSQISAL-----QNEKIAIENKMKQQEDLIQ---NMKLANESSEQSL 2280
Query: 3026 CLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVL----DQALQECE 3193
L+ EN + ++ A L+K KEE +F +E + K+ + + + +Q Q
Sbjct: 2281 SLLEGENSKLEQICANLKKSKEEEIEKMKAMF--NEYKVKVMQDRTEILSQNEQLKQNYI 2338
Query: 3194 ELKNDI---QNKHSDIDSLREEQEKL---NKQLRCMXXXXXXXXXXXXXXXXXXXXISSN 3355
L+N++ +N S+I+SL+ + L N ++ N
Sbjct: 2339 SLQNELASSRNNLSEINSLQSKVNDLQNENSNIKSKANSMLSSMQQKINELQTENINLKN 2398
Query: 3356 LDSMQLELRNYNEELK---NEIEK----KSTDIDLLIKEKEEL-NERLAYTQKAMEQKEA 3511
S EL+N N L+ NE+EK K+++I L ++ EL N+ KA +
Sbjct: 2399 NQSQLNELQNSNNSLQTKLNELEKENETKNSEISSLQQKLNELQNDNTTIKNKANSILNS 2458
Query: 3512 VLVEKLFEGEQKILLLESSQSATRE--------QTE------KYRDLLNSLTEEHADLKK 3649
L +L E + K+ L++ ++ + QTE + ++ +NSL ++L+
Sbjct: 2459 -LNNQLKESQTKLNELQNENTSIKTLETQIHSLQTENETIKSQSQETINSLNSRISELQN 2517
Query: 3650 QFLSATEELQSKERDLEVAMTETKFLKEKL--LVSDENLKEKDLQLRAFEIANSEKQ 3814
Q + +LQS+ DL+ TE + L EK+ L + N K +LQ+ EI +S++Q
Sbjct: 2518 Q-IQEISQLQSELNDLK---TENQSLHEKISELTNSYNSKISELQIENQEILSSKEQ 2570
Score = 141 bits (355), Expect = 3e-30
Identities = 234/1182 (19%), Positives = 481/1182 (40%), Gaps = 81/1182 (6%)
Frame = +2
Query: 518 NGVVSAQEEEFKEALAA----KDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHET 685
N ++Q +E KE +++ +++ LN ++ + N++I L + LQ KE I E
Sbjct: 26 NKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNKNNEIDLLHQQLQSKETEISKLTEN 85
Query: 686 ISERDRLLKDFIHEKDLMQQRAQET----EQKLASRDNEMMHMVLEKDNIILSLHKQIE- 850
+SER++ + + + +Q +ET + KL S+DNE + E ++ + + ++E
Sbjct: 86 VSEREKSFTELQEQLEKAKQEHEETISEIKLKLESKDNE----INELNSTLSQIRSELEQ 141
Query: 851 LQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEI 1030
QNT+ + + E I + + K +E+ E+ + +S+K I
Sbjct: 142 TNKQNTELTETLSQKESNINEINDNLSK---------LREEISEKEKTINEKSSK----I 188
Query: 1031 QSLKDECHAKEMSKQAEISKLSHTLEESIM-NSNLESLFTAEIYENTFRELGDQISQLRN 1207
+ L + K+ S + K+++ EE+ NS +E EL Q+ LRN
Sbjct: 189 EELNQQISEKDNSLKEMTEKINNLEEENKQKNSRIE-------------ELQQQLESLRN 235
Query: 1208 DMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKAS----MEMQCS 1375
D ++ + + S+ + +E N+L Q K S +E S
Sbjct: 236 DDENRINNLYEELSQKESKINELNELMMQQQTGKETILSQLNEQIKEKDSKIGELEENVS 295
Query: 1376 KLKDELEEERGKISENLERISKLQKM-------NNELAERSKSQNSIXXXXXXXXXXXXX 1534
KL+ E+ ++ I+E ++S+ KM NEL ++ QNS+
Sbjct: 296 KLESEISQKESNINELSSQVSEKDKMVNDISEEKNELQKQLSDQNSMID----------- 344
Query: 1535 XXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIE 1714
+++ELTD N+ S + E + S + + IS +T +S+ K EI
Sbjct: 345 -----------ELNEQIKELTD--NLSKSTTESTEKD-SKNQELISEKETEISHLKEEIS 390
Query: 1715 K-------SQKVLQSFESHIE------KLVNDSLHEV-------DSAFCSLNSRFYSLIH 1834
K K++Q I+ K + ++ E+ ++ ++ IH
Sbjct: 391 KLTEQHGEKDKLIQELTEQIQTQDINLKQKDSNISELQVLVSQKETELSEKDNSINEFIH 450
Query: 1835 KVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKE 2014
K++ ++ + + N+ + E + + KE I D V + + + KE
Sbjct: 451 KLEEKDLQIKELNEQLNNKESQINELNAQISDKENSLQEITDKV-----HTLEETVQNKE 505
Query: 2015 EAVVHDDEFDAERIALLNELKSL--HQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQ 2188
+ +E +ER +NEL + +D E+ + E + S ++ + + I +Q
Sbjct: 506 TEINQKNEELSERETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQISNKENSLQ 565
Query: 2189 EGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILA 2368
E D + HS E D T K+V E KL
Sbjct: 566 ELTD-------------KVHSLETKNSEQETQIDELT-----KLVSEKEEENNKLQ---- 603
Query: 2369 FETADASDSPLRNWPKEQLLGHFKQSFAGLKREYE--LELQRKTEEIYDLKRLLLNE-KN 2539
ET ++ +++ K+ + Q + + E E K EE K ++E K
Sbjct: 604 -ETIQTKETEIKD--KQSKVDEMNQEISDKDKSIEEITERVNKLEEENKTKNSQIDEMKE 660
Query: 2540 GLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLL 2719
+ + ++ K ++ ++ L +E + K + EL K++ L
Sbjct: 661 QISSITTNEETAISTLNTQLNNKNNEIDLLHQQLQSKETENEKAI----NELNDKLNKLY 716
Query: 2720 KEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLT 2899
+EI K++N L E++S ++ D + L + I +++ +D+++
Sbjct: 717 EEIANKNTNITELNEQISSKNQEIVDRDNKLQSLGTELNQKNEEIKEKDSKIGEFNDLVS 776
Query: 2900 ALFVEMVREKEFSLSLATKEQETVNQ------KQMSLRKMLEDKDKLLCLVGEE-----N 3046
E+ + +E +++K +E N+ + L + +KD + + EE +
Sbjct: 777 KKDSEINQLQEEIADISSKIEELNNEIATKDASILELNNKIAEKDLKIKSLDEEKSSLQS 836
Query: 3047 KEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQK---RVLDQALQECEELKNDIQN 3217
K +++ I + L + E +QSE +K +E K ++ QA+ E +E + +N
Sbjct: 837 KPAEKENDISDLLVKYDEKCSEIEAVQSELAKKDKENKEFEELMSQAISEKDEEISKSKN 896
Query: 3218 KHSDI-DSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNE 3394
S + + L E+++++N + ++ ++D ++ E+ +E
Sbjct: 897 GISSLQEKLAEKEKEINSKNEANTAEKEENSKLISQRDEEISNLNKSIDELRKEISTKDE 956
Query: 3395 ELK------NEIEKKSTDIDLLIKEKE----ELNERLAYTQ---KAMEQKEAVLVEKLFE 3535
+ NE+ ++ + +L I EKE ELNE++ + +++ E V+ K+ E
Sbjct: 957 TISQFESKINELIEEISKKELTINEKETKIAELNEQITQKENEINGLKEAEKVMETKISE 1016
Query: 3536 GEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATE-------ELQSKERD 3694
E ++ E S + E + +N EE ++ + + E E+Q K +
Sbjct: 1017 IESQLTEKEKSINELEETVQNKETEINQKNEELSERETKINELNEIISQKDSEIQQKNEE 1076
Query: 3695 LEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQYQ 3820
+ ++ L +++ + +L+E ++ + E NSE++ Q
Sbjct: 1077 ISSNNSKIDELNQQISNKENSLQELTDKVHSLETKNSEQETQ 1118
Score = 138 bits (347), Expect = 2e-29
Identities = 243/1222 (19%), Positives = 483/1222 (39%), Gaps = 129/1222 (10%)
Frame = +2
Query: 536 QEEEFKEALAAKDSENFLLNKKIED-------LNHKIWSLEETLQYKEEVILSSHETISE 694
Q +E E L K+S+ LN +I D + K+ +LEET+Q KE I +E +SE
Sbjct: 458 QIKELNEQLNNKESQINELNAQISDKENSLQEITDKVHTLEETVQNKETEINQKNEELSE 517
Query: 695 RDRL---LKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIE-LQSQ 862
R+ L + I +KD Q+ E S+ +E+ + K+N + L ++ L+++
Sbjct: 518 RETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQISNKENSLQELTDKVHSLETK 577
Query: 863 NTQSLDCFRRDEIEDQ-NIKEEIEKQIVETIYVTQ-----------------------IQ 970
N++ + DE+ + KEE ++ ETI + I+
Sbjct: 578 NSEQET--QIDELTKLVSEKEEENNKLQETIQTKETEIKDKQSKVDEMNQEISDKDKSIE 635
Query: 971 ELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTL-----EESIMNSNLE 1135
E+ E + L E+ +I +K++ + +++ IS L+ L E +++ L+
Sbjct: 636 EITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNKNNEIDLLHQQLQ 695
Query: 1136 SLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSEC----NKLQE---- 1291
S T E EL D++++L ++ +KN+ I L +I + E NKLQ
Sbjct: 696 SKETEN--EKAINELNDKLNKLYEEIANKNTNITELNEQISSKNQEIVDRDNKLQSLGTE 753
Query: 1292 --QXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERIS----KLQKM 1453
Q L + + + ++L++E+ + KI E I+ + ++
Sbjct: 754 LNQKNEEIKEKDSKIGEFNDLVSKKDSEINQLQEEIADISSKIEELNNEIATKDASILEL 813
Query: 1454 NNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXV-------------VNMAFGSKLEEL 1594
NN++AE+ S+ + V K +E
Sbjct: 814 NNKIAEKDLKIKSLDEEKSSLQSKPAEKENDISDLLVKYDEKCSEIEAVQSELAKKDKEN 873
Query: 1595 TDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDS 1774
+ + + I +K+ E+S + ISSLQ L+ ++ EI + + + KL++
Sbjct: 874 KEFEELMSQAISEKDEEISKSKNGISSLQEKLAEKEKEINSKNEANTAEKEENSKLISQR 933
Query: 1775 LHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKE----EL 1942
E+ + LN L ++ ET+ F I + ++ + KE EL
Sbjct: 934 DEEISN----LNKSIDELRKEISTKDETISQFESKINELIEEISKKELTINEKETKIAEL 989
Query: 1943 EGHI------------ADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLH 2086
I A+ V+ ++I S KE+++ +E + +N+
Sbjct: 990 NEQITQKENEINGLKEAEKVMETKISEIESQLTEKEKSINELEETVQNKETEINQ----- 1044
Query: 2087 QDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGK---DGEASDVQGKSRALRRHSTG 2257
++ EL + E + L+ + I ++ I D + K +L+ +
Sbjct: 1045 KNEELSERETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQISNKENSLQELTDK 1104
Query: 2258 QAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHF 2437
E E K+V E KL ET ++ +++ K+ +
Sbjct: 1105 VHSLETKNSEQETQIEELTKLVSEKEEENNKLQ-----ETIQTKETEIKD--KQSKVDEM 1157
Query: 2438 KQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEK 2617
Q + + E E+ + ++ + + ++ + + ++ + +
Sbjct: 1158 NQEISDKDKSIE-EITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNN 1216
Query: 2618 VLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLK---EIKEKDSNSKVLAEKLSDALKK 2788
E LL + + + L EE+ + ++L EIKEK+ L + +S KK
Sbjct: 1217 KNNEIDLLHQQLQSKETEIKQLNEEISERNNALQTKETEIKEKELKINELNDIIS---KK 1273
Query: 2789 SADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEM----------------- 2917
+ A++ES L ++I L T+RE + S+ L L ++
Sbjct: 1274 EEEKAEKESLLNENINKLN---TERESQINELSEKLLKLEEQLKQETLSNEDMKQTNTSL 1330
Query: 2918 ---VREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKE----HKRQIAIL 3076
+ E F LS T + + +NQ+ L + DKDK + + EE KE ++ I+
Sbjct: 1331 SQKIDEMAFQLSDKTSQLQELNQQITVLSSQISDKDKTVNDLQEEIKEKSVQNEENSRII 1390
Query: 3077 EKLKEETENNPGRVFLQSEEREKIEEQKRVL---------------DQALQECEELKNDI 3211
LKE + + + E+ + IE++K Q EL+N +
Sbjct: 1391 NDLKEFIKQYDEDIKSKDEKIKSIEQEKDAKINEIKAELETKETENSQLFGNISELQNML 1450
Query: 3212 QNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYN 3391
++ S+ +++ + KL +++ + +S L E+ N+N
Sbjct: 1451 SSRDSEYETVCSDNNKLKQEIEAL----------KSSLSEKENDFASILSKYDEEVSNHN 1500
Query: 3392 EELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQ 3571
+E++ E+ KK + + EKE ++ +K +E ++ L EK E + +
Sbjct: 1501 KEVE-ELTKKDEENKQQVDEKE---NEISNLKKEIENLKSSLNEKDNE-------ISQNS 1549
Query: 3572 SATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTE-TKFLKEKLLVS 3748
A + ++ ++L + E+ +++ + EEL + ++ LE +E T L+EK
Sbjct: 1550 QAIDDSSKHVQELQHQFDEDLKQKQEEISAKDEELSNLKKVLEEEKSEITSSLQEK---- 1605
Query: 3749 DENLKEKDLQLRAFEIANSEKQ 3814
DE +K+K+ ++ EK+
Sbjct: 1606 DELIKQKEEEISNLNSVIQEKE 1627
Score = 115 bits (288), Expect = 1e-22
Identities = 234/1187 (19%), Positives = 495/1187 (41%), Gaps = 45/1187 (3%)
Frame = +2
Query: 377 LKNMNFDLGQDNPGVPGLLED----IRNTKDLLDTVESGLYVSNVVSDAV--LNGVVSAQ 538
L + ++ + + G+ ++ D I N L T S L +++ AV + S
Sbjct: 2088 LDSAEIEMNKKSQGMMTMMNDKNGLIENLTKELQTTRSQL--NDIKQQAVYQMQQQKSFD 2145
Query: 539 EEEFKEA---LAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLL 709
++E + ++ K SEN + ++ N + ++ +T+Q K+E+I ++ + ++LL
Sbjct: 2146 DQEIQRLNGLISQKLSENEQMRQQF---NLQADAMNKTIQEKDEMI---NQIKTRANKLL 2199
Query: 710 KDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFR 889
+ ++E +Q +E E+KL+ ++NE+ + + + +I + QI
Sbjct: 2200 NEKLNENSNLQNLQKENEEKLSQKENELNQIKSQLNTVIQNAQSQISAL----------- 2248
Query: 890 RDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMS 1069
QN K IE ++ + + Q +L E L + + E L+ C + S
Sbjct: 2249 ------QNEKIAIENKMKQQEDLIQNMKLANESSEQSL--SLLEGENSKLEQICANLKKS 2300
Query: 1070 KQAEISKLSHTLEE---SIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDS 1240
K+ EI K+ E +M E L E + + L ++++ RN++ S I+S
Sbjct: 2301 KEEEIEKMKAMFNEYKVKVMQDRTEILSQNEQLKQNYISLQNELASSRNNL----SEINS 2356
Query: 1241 LASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDE---LEEERGK 1411
L S+++ L +E + ++ + ++ +SM+ + ++L+ E L+ + +
Sbjct: 2357 LQSKVNDLQNENSNIKSKAN--------------SMLSSMQQKINELQTENINLKNNQSQ 2402
Query: 1412 ISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEE 1591
++E + LQ NEL + ++++NS S L++
Sbjct: 2403 LNELQNSNNSLQTKLNELEKENETKNSEI--------------------------SSLQQ 2436
Query: 1592 LTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVND 1771
+++ N+ I K +S+ L+NQ +++SQ L ++ N
Sbjct: 2437 KLNELQNDNTTIKNKA----------NSILNSLNNQ---LKESQTKLNELQNE-----NT 2478
Query: 1772 SLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVA-VSQEQHIEHQCKEE--- 1939
S+ +++ SL + ++ + + +L + + +QNQ+ +SQ Q + K E
Sbjct: 2479 SIKTLETQIHSLQTENETIKSQSQETINSLNSRISELQNQIQEISQLQSELNDLKTENQS 2538
Query: 1940 LEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELL---KA 2110
L I++L N +++ I +E + ++ + L+EL++ +Q L+L K
Sbjct: 2539 LHEKISELT-NSYNSKISELQIENQEILSSKEQISQSK---LSELQNENQSLKLQISEKE 2594
Query: 2111 EEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPED 2290
EE K +++N + + L++E E S +Q + G + E+
Sbjct: 2595 EENEKLMNSNSELMNQ-----IDLVKEDTKKEISHLQATINEKQTKIDGLNSQISQNEEE 2649
Query: 2291 LYTTYSEGKIVEPHPT--EEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQS----FA 2452
GK+ T E+K + IL + +D +S L N K K S F
Sbjct: 2650 RI-----GKLESLQSTIDEDKSQIEILEQKVSDL-ESKLENLQKHYSEIETKNSQYENFI 2703
Query: 2453 GLKR----EYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEK- 2617
R E + ++ + E LK ++N +N + + + E K E+
Sbjct: 2704 SKARVAFNENKAKISQLETENNSLKEKVVNYENAISSNDSQLKNFISQ-MKEENSKLEEE 2762
Query: 2618 ---VLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKK 2788
+++EN+ +P E + K + K+ + +E +E+ +K+L EK S+ ++
Sbjct: 2763 KSQLIKENQRIPQLEEEN-KQFANQLSKFNEKLTQIDRETEEE--KTKLLTEK-SNLEEE 2818
Query: 2789 SADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQET 2968
Q+ + LE E ++ S + + +E + + KE+E
Sbjct: 2819 IKQLKQQNEEINNEKVQLE------EQFSNAKSKLAEEINQIKKPNEEINNDQSNKEEEK 2872
Query: 2969 VNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKI 3148
++ + + L ++ L + + + E + L ++K++ E + L + ++ ++
Sbjct: 2873 SKLREQ-INEFLNERTHLQEQIHQISNEKSQLQEELNEVKKQNEKINEEIQLLNNDKSQL 2931
Query: 3149 EEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXX 3328
+E K L++ L++ E+ QN S + ++ EK L+
Sbjct: 2932 QEDKSALEEVLKQMEQ-----QNDQSSTEEMKSNYEKQINDLQSKVSELENKLISQTEEK 2986
Query: 3329 XXXXXISSNLDSMQLELRNYNEELKNE---IEKKSTDIDLLIKEKEELNERLAYTQKAME 3499
+NL+S+ +LRN N+ ++ E EK+ D+ + ++ +++ T+ +
Sbjct: 2987 SQI----ANLESVIEKLRNENKNIEEEKLKFEKQVKDLQTNAETNDQREDKI--TELKLR 3040
Query: 3500 QKEAVLVEKLFEGEQKILLLESS----QSATREQTEKYRDLLNSLTEEHADLKKQFLSAT 3667
E K ++ +I LL++ QS Q +KY + +NS T+ +
Sbjct: 3041 NAELQQQMKDYQNNSQINLLQNQIKDLQSQISAQKQKYEEQINSQTKNEEE--------D 3092
Query: 3668 EELQSKERDLEVAMTETKFLKEKLLVSDENLKEK--DLQLRAFEIAN 3802
E ++ RD+ + E K +KL +E LK+K DL+ + N
Sbjct: 3093 EGIEVVNRDINLDEGE-KDDFQKLKEENEQLKKKISDLETKLNSYVN 3138
Score = 100 bits (249), Expect = 5e-18
Identities = 265/1385 (19%), Positives = 520/1385 (37%), Gaps = 216/1385 (15%)
Frame = +2
Query: 314 ETKIAETLERMEIHEGDTANT----LKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESG 481
+ +I+ E++ I D NT + ++N L Q + + L +I+ + L ++S
Sbjct: 1694 DKEISSLQEKVNIENNDV-NTKETEISSLNDQLKQKDEEINNLKSEIKEKFEELSKLQS- 1751
Query: 482 LYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEE----TLQ 649
L N L V++ E + L K+ E LN I++ +I L+E +L
Sbjct: 1752 LVNENEQVIVSLQEKVNSDEINKENELKMKEEEISNLNGSIQEKEKEISLLKENFNNSLA 1811
Query: 650 YKEEVILSSHETISERDR-----------LLKDFIHEKDLMQQRAQETEQKLASRDNEMM 796
K+E I + + + E L+ I E+D +Q++ +E Q L++ E++
Sbjct: 1812 QKDEEISNLKKVLEEEKSGITSSLQEQISKLQSEIKERDEIQKKKEEEIQTLSNEKLELL 1871
Query: 797 HMVLEKDNIILS-LHKQIELQSQNT-QSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQ 970
E+ N++ S L++ +EL Q + + + EI Q KE E Q ++
Sbjct: 1872 KQKEEEINVLNSKLNESVELLKQKEGDNENNDKISEIRQQKEKEISELQSEINSLKNELS 1931
Query: 971 ELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTA 1150
EE + L + +EI S+K + + S+ IS + +++ + N ES+
Sbjct: 1932 ANKEEMEKLNETIKERDEEISSIKQKAD-DDKSEVNSISNILSDIKQKLSNQTQESIKEG 1990
Query: 1151 EIYENTFRELGDQ---ISQLR-NDMYSKNSYI------------------DSLASRIDFL 1264
++ RE+ D+ ISQL + + SK S + + + S +++L
Sbjct: 1991 RVFSKE-REVPDEETNISQLDYSPIKSKPSEVVKSREVIELVDEDEGNETNDIRSTVEYL 2049
Query: 1265 SSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENL-----E 1429
S +++Q +L Q L D E E K S+ + +
Sbjct: 2050 SETIDEMQANIEELKKENAKKSQEKQSL-IYQNQQLRILLDSAEIEMNKKSQGMMTMMND 2108
Query: 1430 RISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKL---EELTD 1600
+ ++ + EL N I +N KL E++
Sbjct: 2109 KNGLIENLTKELQTTRSQLNDIKQQAVYQMQQQKSFDDQEIQRLNGLISQKLSENEQMRQ 2168
Query: 1601 QINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLH 1780
Q N+ ++K E ++ I + L N+K + LQ+ + E+ ++ +
Sbjct: 2169 QFNLQADAMNKTIQEKDEMINQIKTRANKLLNEKLNENSN---LQNLQKENEEKLSQKEN 2225
Query: 1781 EVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEE----LEG 1948
E++ LN+ + ++ A ++ Q + Q + ++ E+ LEG
Sbjct: 2226 ELNQIKSQLNTVIQNAQSQISALQNEKIAIENKMKQQEDLIQNMKLANESSEQSLSLLEG 2285
Query: 1949 HIADL--------------------VLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLN 2068
+ L + N++ ++ + + E + +++ I+L N
Sbjct: 2286 ENSKLEQICANLKKSKEEEIEKMKAMFNEYKVKVM---QDRTEILSQNEQLKQNYISLQN 2342
Query: 2069 ELKSLHQDL-ELLKAEEAVKSLSN-NVGVSTKGIHYFSQLIQE------------GKDGE 2206
EL S +L E+ + V L N N + +K S + Q+ +
Sbjct: 2343 ELASSRNNLSEINSLQSKVNDLQNENSNIKSKANSMLSSMQQKINELQTENINLKNNQSQ 2402
Query: 2207 ASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSE-GKIVEPHPTEEKKLLAIL------ 2365
+++Q + +L+ K ++ + + ++ + T + K +IL
Sbjct: 2403 LNELQNSNNSLQTKLNELEKENETKNSEISSLQQKLNELQNDNTTIKNKANSILNSLNNQ 2462
Query: 2366 ----------------AFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTE 2497
+ +T + L+ E + +++ L ELQ + +
Sbjct: 2463 LKESQTKLNELQNENTSIKTLETQIHSLQT-ENETIKSQSQETINSLNSRIS-ELQNQIQ 2520
Query: 2498 EIYDLKRLLLN---EKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYK 2668
EI L+ L + E LH ++E+ + +++L E++ + K
Sbjct: 2521 EISQLQSELNDLKTENQSLHEKISELTNSYNSKISELQIENQEILSSK-----EQISQSK 2575
Query: 2669 MLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEA 2848
+ ELQ++ SL +I EK+ ++ L S+ L D + ++ K I+ L+A
Sbjct: 2576 L-----SELQNENQSLKLQISEKEEENEKLMNSNSE-LMNQIDLVKEDTK--KEISHLQA 2627
Query: 2849 GITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQ---ETVNQKQMSLRKMLEDKDK 3019
I +++ + ++ E + + E S +++ E + QK L LE+ K
Sbjct: 2628 TINEKQTKIDGLNSQISQNEEERIGKLESLQSTIDEDKSQIEILEQKVSDLESKLENLQK 2687
Query: 3020 LLCLVGEENKEH-----KRQIAILEKLKE----ETENNPGRVFLQSEER---EKIEEQKR 3163
+ +N ++ K ++A E + ETENN + + + E + K
Sbjct: 2688 HYSEIETKNSQYENFISKARVAFNENKAKISQLETENNSLKEKVVNYENAISSNDSQLKN 2747
Query: 3164 VLDQALQE---CEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXX 3334
+ Q +E EE K+ + ++ I L EE ++ QL
Sbjct: 2748 FISQMKEENSKLEEEKSQLIKENQRIPQLEEENKQFANQLSKFNEKLTQIDRETEEEKTK 2807
Query: 3335 XXXISSNLDSMQLELRNYNEELKNE---------------------IEKKSTDIDLLIKE 3451
SNL+ +L+ NEE+ NE I+K + +I+
Sbjct: 2808 LLTEKSNLEEEIKQLKQQNEEINNEKVQLEEQFSNAKSKLAEEINQIKKPNEEINNDQSN 2867
Query: 3452 KEE------------LNERL--------AYTQKAMEQKEAVLVEKLFEG-EQKILLL--- 3559
KEE LNER +K+ Q+E V+K E ++I LL
Sbjct: 2868 KEEEKSKLREQINEFLNERTHLQEQIHQISNEKSQLQEELNEVKKQNEKINEEIQLLNND 2927
Query: 3560 --------------------ESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEE-- 3673
++ QS+T E Y +N L + ++L+ + +S TEE
Sbjct: 2928 KSQLQEDKSALEEVLKQMEQQNDQSSTEEMKSNYEKQINDLQSKVSELENKLISQTEEKS 2987
Query: 3674 -LQSKERDLEVAMTETKFLKEKLLVSDENLKE---------------KDLQLRAFEIANS 3805
+ + E +E E K ++E+ L ++ +K+ +L+LR E+
Sbjct: 2988 QIANLESVIEKLRNENKNIEEEKLKFEKQVKDLQTNAETNDQREDKITELKLRNAELQQQ 3047
Query: 3806 EKQYQ 3820
K YQ
Sbjct: 3048 MKDYQ 3052
Score = 89.7 bits (221), Expect = 9e-15
Identities = 148/771 (19%), Positives = 304/771 (39%), Gaps = 25/771 (3%)
Frame = +2
Query: 1583 LEELTDQINIF-------NSVIDKKEAEVS----GHLDTISSLQTVLSNQKFEIEKSQKV 1729
+EE+T+++N NS ID+ + ++S IS+L T L+N+ EI+ +
Sbjct: 12 IEEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNKNNEIDLLHQQ 71
Query: 1730 LQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQE 1909
LQS E+ I KL +N E ++F + +Q Q+ +++
Sbjct: 72 LQSKETEISKL-------------------------TENVSEREKSFTE-LQEQLEKAKQ 105
Query: 1910 QHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFD---AERIALLNELKS 2080
+H E + +L+ D +N+ ++ + E+ + E +++ + +NE+
Sbjct: 106 EHEETISEIKLKLESKDNEINELNSTLSQIRSELEQTNKQNTELTETLSQKESNINEIND 165
Query: 2081 LHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQ 2260
L K E + + + I +Q I E KD ++ K L
Sbjct: 166 -----NLSKLREEISEKEKTINEKSSKIEELNQQISE-KDNSLKEMTEKINNLE------ 213
Query: 2261 AFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFK 2440
EE K K + +
Sbjct: 214 --------------------------EENK--------------------QKNSRIEELQ 227
Query: 2441 QSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKV 2620
Q L+ + E + EE+ K +NE N L + + TGK +
Sbjct: 228 QQLESLRNDDENRINNLYEEL-SQKESKINELNEL-------------MMQQQTGKETIL 273
Query: 2621 LQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADH 2800
Q N+ + ++ + EL+ + L EI +K+SN L+ ++S+ K D
Sbjct: 274 SQLNEQIKEKDSK--------IGELEENVSKLESEISQKESNINELSSQVSEKDKMVNDI 325
Query: 2801 AQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQK 2980
++ ++ L K ++D + I + +D L+ E EK+ +K QE +++K
Sbjct: 326 SEEKNELQKQLSDQNSMIDELNEQIKELTDNLSKSTTEST-EKD------SKNQELISEK 378
Query: 2981 QMSLRKMLEDKDKLLCLVGEENK---EHKRQIAILE-KLKEETENNPGRVFLQSEEREKI 3148
+ + + E+ KL GE++K E QI + LK++ N L S++ ++
Sbjct: 379 ETEISHLKEEISKLTEQHGEKDKLIQELTEQIQTQDINLKQKDSNISELQVLVSQKETEL 438
Query: 3149 EEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXX 3328
E+ +++ + + EE I+ + +++ + +LN Q+
Sbjct: 439 SEKDNSINEFIHKLEEKDLQIKELNEQLNNKESQINELNAQI-------SDKENSLQEIT 491
Query: 3329 XXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEK----EELNERLAYTQKAM 3496
+ + + + E+ NEEL +E E K +++ +I +K ++ NE ++ +
Sbjct: 492 DKVHTLEETVQNKETEINQKNEEL-SERETKINELNEIISQKDSEIQQKNEEISSNNSKI 550
Query: 3497 EQKEAVLVEK---LFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSAT 3667
++ + K L E K+ LE+ S Q ++ L++ EE+ L+
Sbjct: 551 DELNQQISNKENSLQELTDKVHSLETKNSEQETQIDELTKLVSEKEEENNKLQ------- 603
Query: 3668 EELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQYQ 3820
E +Q+KE +++ ++ + +++ D++++E ++ E N K Q
Sbjct: 604 ETIQTKETEIKDKQSKVDEMNQEISDKDKSIEEITERVNKLEEENKTKNSQ 654
Score = 87.0 bits (214), Expect = 6e-14
Identities = 194/1000 (19%), Positives = 396/1000 (39%), Gaps = 47/1000 (4%)
Frame = +2
Query: 371 NTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEF 550
N L+ N +L + L +++N+ + L T + L N ++ ++ + E
Sbjct: 2387 NELQTENINLKNNQ----SQLNELQNSNNSLQTKLNELEKENETKNSEISSLQQKLNELQ 2442
Query: 551 KEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEK 730
+ K+ N +LN LN+++ + Q K + + + +I + + E
Sbjct: 2443 NDNTTIKNKANSILNS----LNNQL----KESQTKLNELQNENTSIKTLETQIHSLQTEN 2494
Query: 731 DLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHK-QIELQS--QNTQSLDCFRRDEI 901
+ ++ ++QET L SR +E+ + + E + L+ + E QS + L +I
Sbjct: 2495 ETIKSQSQETINSLNSRISELQNQIQEISQLQSELNDLKTENQSLHEKISELTNSYNSKI 2554
Query: 902 EDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECH--------A 1057
+ I+ + E I +++ EL E+ L+L+ ++ ++E + L +
Sbjct: 2555 SELQIENQEILSSKEQISQSKLSELQNENQSLKLQISEKEEENEKLMNSNSELMNQIDLV 2614
Query: 1058 KEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYID 1237
KE +K+ EIS L T+ E + ++ L ++I +N +G ++ L++ + S I+
Sbjct: 2615 KEDTKK-EISHLQATINEK--QTKIDGL-NSQISQNEEERIG-KLESLQSTIDEDKSQIE 2669
Query: 1238 SLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKIS 1417
L ++ L S+ LQ+ + +E + S+ ++ + + R +
Sbjct: 2670 ILEQKVSDLESKLENLQKHY------------------SEIETKNSQYENFISKARVAFN 2711
Query: 1418 ENLERISKLQKMNNELAERSKS-QNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEEL 1594
EN +IS+L+ NN L E+ + +N+I SKLEE
Sbjct: 2712 ENKAKISQLETENNSLKEKVVNYENAISSNDSQLKNFISQMKEE---------NSKLEEE 2762
Query: 1595 TDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIE---KLV 1765
Q+ N I + E E + +S L+ E E+ + L + +S++E K +
Sbjct: 2763 KSQLIKENQRIPQLEEENKQFANQLSKFNEKLTQIDRETEEEKTKLLTEKSNLEEEIKQL 2822
Query: 1766 NDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQH--IEHQCKEE 1939
E+++ L +F + K+ ++ + I N + +E+ + Q E
Sbjct: 2823 KQQNEEINNEKVQLEEQFSNAKSKLAEEINQIKKPNEEINNDQSNKEEEKSKLREQINEF 2882
Query: 1940 LEG--HIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAE 2113
L H+ + + + SN+ E +++ + E L N+ L +D L E
Sbjct: 2883 LNERTHLQEQI-HQISNEKSQLQEELNEVKKQNEKINEEIQLLNNDKSQLQEDKSAL--E 2939
Query: 2114 EAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDL 2293
E +K + S+ ++ ++ + + +D+Q K L Q E + +L
Sbjct: 2940 EVLKQMEQQNDQSS------TEEMKSNYEKQINDLQSKVSELENKLISQT-EEKSQIANL 2992
Query: 2294 YTTYSEGKIVEPHPTEEKKLLAILAFE--TADASDSPLRNWPKEQLLGHFKQSFAGLKRE 2467
+ + + + EEK L FE D + N +E + K R
Sbjct: 2993 ESVIEKLRNENKNIEEEK-----LKFEKQVKDLQTNAETNDQREDKITELKL------RN 3041
Query: 2468 YELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEK-----VLQEN 2632
EL+ Q K + LL N+ L + + T E+ V+ +
Sbjct: 3042 AELQQQMKDYQNNSQINLLQNQIKDLQSQISAQKQKYEEQINSQTKNEEEDEGIEVVNRD 3101
Query: 2633 KLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDA---LKKSADHA 2803
L E ++ L E+L+ KI L ++ + + +L +K+++ + S D+
Sbjct: 3102 INLDEGEKDDFQKLKEENEQLKKKISDLETKLNSYVNENAILQQKIAELGGDIDVSIDYG 3161
Query: 2804 QRESHLL------------------KHIADLEAGITDREIMTSVCSDVLTALFVEMVREK 2929
+ ++ K I DLE I + SV + A E ++E
Sbjct: 3162 SDKDAIIAKLRILLQRALRLDKKRVKTIEDLEEKI--KSFGVSVHNSSYEAQLEEQIKEL 3219
Query: 2930 EFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNP 3109
+ + + + QK SL+KM++ K L G+ +E+++ I L+ K ++++
Sbjct: 3220 KQKIENNEASDDLI-QKNESLKKMVQ---KSNTLYGQLMEENQQLIKTLKSYKAKSDSG- 3274
Query: 3110 GRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSD 3229
S ++ Q +++ E EE+ Q +D
Sbjct: 3275 ------SSPKKPTRVQLKIVSTNETEIEEIVTPSQTNRND 3308
Score = 73.9 bits (180), Expect = 5e-10
Identities = 128/718 (17%), Positives = 295/718 (41%), Gaps = 78/718 (10%)
Frame = +2
Query: 296 DTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGL--------------- 430
++ SL+TK+ E + E + ++ + +N +L DN +
Sbjct: 2408 NSNNSLQTKLNELEKENETKNSEISSLQQKLN-ELQNDNTTIKNKANSILNSLNNQLKES 2466
Query: 431 ---LEDIRNTKDLLDTVESGLYVSNVVSDAV----------LNGVVSAQEEEFKEALAAK 571
L +++N + T+E+ ++ ++ + LN +S + + +E +
Sbjct: 2467 QTKLNELQNENTSIKTLETQIHSLQTENETIKSQSQETINSLNSRISELQNQIQEISQLQ 2526
Query: 572 D------SENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEKD 733
+EN L++KI +L + S LQ + + ILSS E IS+ L + +E
Sbjct: 2527 SELNDLKTENQSLHEKISELTNSYNSKISELQIENQEILSSKEQISQSK--LSELQNENQ 2584
Query: 734 LMQQRAQETE---QKLASRDNEMMHM------------------VLEKDNIILSLHKQI- 847
++ + E E +KL + ++E+M+ + EK I L+ QI
Sbjct: 2585 SLKLQISEKEEENEKLMNSNSELMNQIDLVKEDTKKEISHLQATINEKQTKIDGLNSQIS 2644
Query: 848 ELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDE 1027
+ + + L+ + ED++ E +E+++ + ++++ L + + + ++++Y++
Sbjct: 2645 QNEEERIGKLESLQSTIDEDKSQIEILEQKVSD--LESKLENLQKHYSEIETKNSQYENF 2702
Query: 1028 IQSLKDECHAKEMSKQAEISKLSHTLEESIMN-SNLESLFTAEI--YENTFRELGDQISQ 1198
I + + +K +++ +++L+E ++N N S +++ + + +E ++ +
Sbjct: 2703 ISKAR-VAFNENKAKISQLETENNSLKEKVVNYENAISSNDSQLKNFISQMKEENSKLEE 2761
Query: 1199 LRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSK 1378
++ + +N I L +++ +K E+ T K+++E + +
Sbjct: 2762 EKSQLIKENQRIPQLEEENKQFANQLSKFNEKLTQIDRETEEEKTKLLTEKSNLEEEIKQ 2821
Query: 1379 LKDELEE--------------ERGKISENLERISK-LQKMNNELAERSKSQNSIXXXXXX 1513
LK + EE + K++E + +I K +++NN+ + + + ++ +
Sbjct: 2822 LKQQNEEINNEKVQLEEQFSNAKSKLAEEINQIKKPNEEINNDQSNKEEEKSKLREQINE 2881
Query: 1514 XXXXXXXXXXXXXXVVN--MAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTV 1687
+ N +L E+ Q N I + S + S+L+ V
Sbjct: 2882 FLNERTHLQEQIHQISNEKSQLQEELNEVKKQNEKINEEIQLLNNDKSQLQEDKSALEEV 2941
Query: 1688 LSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRF--YSLIHKVDNSGETL 1861
L ++ E + Q + +S+ EK +ND +V L S+ S I +++ E L
Sbjct: 2942 L--KQMEQQNDQSSTEEMKSNYEKQINDLQSKVSELENKLISQTEEKSQIANLESVIEKL 2999
Query: 1862 RAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEF 2041
R KNI+ + K + E + DL N +ND ++E+ + E
Sbjct: 3000 RNENKNIEEE-------------KLKFEKQVKDLQTNAETND------QREDKIT---EL 3037
Query: 2042 DAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASD 2215
L ++K + ++ + +K L + +S + Y Q+ + K+ E +
Sbjct: 3038 KLRNAELQQQMKDYQNNSQINLLQNQIKDLQSQ--ISAQKQKYEEQINSQTKNEEEDE 3093
>ref|XP_001304086.1| hypothetical protein [Trichomonas vaginalis G3]
gi|121885514|gb|EAX91156.1| hypothetical protein
TVAG_497970 [Trichomonas vaginalis G3]
Length = 1684
Score = 140 bits (353), Expect = 4e-30
Identities = 257/1217 (21%), Positives = 488/1217 (40%), Gaps = 74/1217 (6%)
Frame = +2
Query: 305 KSLETKIAETLERMEIHEGDTANTLKNM---NFDLGQDNPGVPGLLEDIRNTKDLLDTVE 475
K E KI E + + I E N L M +++L N L++ I + K L E
Sbjct: 450 KDCEDKIIENICLLLIGEEKVYNALTEMKSNSYELW--NEFEEDLIKIIMDKKPL----E 503
Query: 476 SGLYVSNVVSDAVLNGVVSAQEE-EFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQY 652
+ N+ + V + ++ + K+ + ++ +N +K+ DL +I L + +
Sbjct: 504 NVSQFDNLTDEEVKKELKKLNDDLKEKDKIIEENEKNN--EQKVSDLKKQIEDLSKQKEN 561
Query: 653 KEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMM----HMVLEKDN 820
+ +L + + + ++ LK+ EK+ Q+ ++ + L + D + + V E
Sbjct: 562 ENSDVLQKLDNLQKENQKLKEENEEKESELQKLKQENENLKNIDAQKVTYDDEKVSELQK 621
Query: 821 IILSLHKQIELQSQNTQSLDCFRRDEIED--QNIKEEIEKQIVETIY-VTQIQELGEEHD 991
II L K+ EL ++ D + E++ +++K E EK E VT +Q+ E+D
Sbjct: 622 IIEDLKKENELIQNQKETNDNEKISELQKIVEDLKNENEKLKSEVNQKVTDLQKAEGEND 681
Query: 992 LLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEE---SIMNSNLESLFTAEIYE 1162
L++ K Q+E +++E K EIS+L+ LE+ + N + E + +I
Sbjct: 682 LIK----KLQEENLEIENE-------KDKEISELNEKLEKLQNQVNNLSSEKVTKDDIIS 730
Query: 1163 NTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXX 1342
+ E+ D ++ + K I+SL +I+ L +E LQ+
Sbjct: 731 SLQSEVNDLQEEIESRKDDKQKEINSLKEKIETLENEKISLQDSMNEEIHKLEEEISNLQ 790
Query: 1343 TLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXX 1522
K+ +E + KL ++EE + K + E +L K N E+ E+ Q+
Sbjct: 791 NEKSVLETENEKLSKQIEELQEKEKSSQEENEELSKQNEEMKEKLSKQDKEFEEEKEKLN 850
Query: 1523 XXXXXXXXXXXVVNMA-------FGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQ 1681
N F +++ + + I+ N I + E E S + ++ LQ
Sbjct: 851 AKIEKIEKDLSDGNNEKETLTNDFEDEVKRIEEDIDNKNKQIKQLEEEKSQLNEEMNKLQ 910
Query: 1682 T---VLSNQKFEIE-KSQKVLQSFESHIEKLVNDSLHEVDSAFC-----------SLNSR 1816
L QK +E ++ K+ + FES + L E+ F + S
Sbjct: 911 LNNEFLQKQKDVVETENNKIKKDFESLLSSLNKPDKSEMIKKFDEEKQQELEKTKTAKSE 970
Query: 1817 FYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKE-ELEGHIADL---------V 1966
+ IH++ + L ++ ++N Q ++Q K E+ ++ DL +
Sbjct: 971 LENQIHQMSIEKQKLTINLEKLENDKLNLQNIVNDYQSKNSEMTKNLQDLQKKNFDLQNL 1030
Query: 1967 LNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVG 2146
+D N + R E+++ + DE + +LK +LE K E ++SL NN
Sbjct: 1031 YDDLINKTNEQNHRNEKSLENKDEE-------IKQLKDTQHELES-KIESQLESLQNNEE 1082
Query: 2147 VSTKGIHYFSQLIQEGK-------DGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTY 2305
K + + ++E K + S+++ K L+ +S E E
Sbjct: 1083 -KIKLLESKIEDLEEEKLEQNNINQNKISELEHKIEELQNNSLNNDENENKISE------ 1135
Query: 2306 SEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQ 2485
E ++ E T EK I E + + + + L++E +L Q
Sbjct: 1136 LENQVQEYQETIEKLRKQIEELEKEKENKADTSETESSTKIKELEDKIEELEKENDL-FQ 1194
Query: 2486 RKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRY 2665
+ E I DL+ + N + + ++T K E ++NK L +
Sbjct: 1195 NEGESILDLQEEVTKLNNEIST------------LRQLTCKLE---EDNKTLKDGSEEDE 1239
Query: 2666 KMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLE 2845
K++ L+++L+ K KE + ++ N + LS L K D +RE + +
Sbjct: 1240 KLISSLRKQLKEKE----KEKESENDNISQIKTNLS-VLSKENDKLKREMQMK------D 1288
Query: 2846 AGITDREIMTSVCSDVLTALFVEM-VREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKL 3022
I+D I+TS L ++ +++KE + + K ETV Q + K DK
Sbjct: 1289 DKISDLSILTSSLRTENEHLKSDLDIKKKE--IDIIKKNDETV-QSALDQIKNSNSSDKT 1345
Query: 3023 LCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELK 3202
+ + + Q LEK E+ Q ++ + K L +E ++K
Sbjct: 1346 IKSLQSQLSVCCMQKETLEKELEDMRKEDQETIAQLKQVVNELQTKISLSSPQREFNQMK 1405
Query: 3203 NDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSN--------- 3355
++ K I+ LR+E ++L ++ + SS
Sbjct: 1406 IQLKQKQEQIERLRQENDELQNKVNYIKEKAKNDIKDIIKKTQVPEVKSSEKTLSEVSDL 1465
Query: 3356 ------LDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAME-QKEAV 3514
D +L N ELK +++ S L +EKE + + T+K E ++E
Sbjct: 1466 RRKVLMFDKENQKLTEQNNELKKQLQSISV---LEQREKEYITQISKLTKKTKELEEENK 1522
Query: 3515 LVEKLFEG----EQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQS 3682
L++K E EQ+ L ++ S + + + +N+LT++ + LKKQ L +E+Q
Sbjct: 1523 LIKKSEEDKTDIEQRYLDTVTNTSKMSHEIQTLNETINTLTQKLSQLKKQHLQEKKEMQI 1582
Query: 3683 KERDLEVAMTETKFLKE 3733
+ L+ ++ + LKE
Sbjct: 1583 EVSTLKTSLDSS--LKE 1597
Score = 92.8 bits (229), Expect = 1e-15
Identities = 156/756 (20%), Positives = 315/756 (41%), Gaps = 21/756 (2%)
Frame = +2
Query: 1607 NIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKF--EIEKSQKVLQSFESHIEKLVNDSLH 1780
++ ++DKK E D ++ + +K ++++ K+++ E + E+ V+D
Sbjct: 491 DLIKIIMDKKPLENVSQFDNLTDEEVKKELKKLNDDLKEKDKIIEENEKNNEQKVSDLKK 550
Query: 1781 EVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIAD 1960
+++ + ++ K+DN + +NQ + KEE E ++
Sbjct: 551 QIEDLSKQKENENSDVLQKLDNLQK---------ENQ-----------KLKEENEEKESE 590
Query: 1961 LVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNN 2140
L N+ L + V +DDE +E ++ +LK ++ EL++ + K ++N
Sbjct: 591 LQKLKQENENLK--NIDAQKVTYDDEKVSELQKIIEDLK---KENELIQNQ---KETNDN 642
Query: 2141 VGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKI 2320
+S + + ++ + S+V K L++ + + E+L + K
Sbjct: 643 EKISE--LQKIVEDLKNENEKLKSEVNQKVTDLQKAEGENDLIKKLQEENLEIENEKDKE 700
Query: 2321 VEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEE 2500
+ +E + L L + + S + K+ ++ + L+ E E K +E
Sbjct: 701 I----SELNEKLEKLQNQVNNLSSEKVT---KDDIISSLQSEVNDLQEEIESRKDDKQKE 753
Query: 2501 IYDLKR---LLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKM 2671
I LK L NEK L + ++ + + E +L E + K
Sbjct: 754 INSLKEKIETLENEKISLQ-------DSMNEEIHKLEEEISNLQNEKSVLETENEKLSKQ 806
Query: 2672 LCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIA-DLEA 2848
+ EELQ K S +E +E ++ + EKLS K+ + ++ + ++ I DL
Sbjct: 807 I----EELQEKEKSSQEENEELSKQNEEMKEKLSKQDKEFEEEKEKLNAKIEKIEKDLSD 862
Query: 2849 GITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLC 3028
G ++E +T+ D + + +E ++ K ++++ E+K +L
Sbjct: 863 GNNEKETLTNDFEDEVKRI------------------EEDIDNKNKQIKQLEEEKSQL-- 902
Query: 3029 LVGEENKEHKRQIAILEKLKE--ETENNPGRVFLQS-----EEREKIEEQKRVLDQALQE 3187
EE + + L+K K+ ETENN + +S + +K E K+ ++ QE
Sbjct: 903 --NEEMNKLQLNNEFLQKQKDVVETENNKIKKDFESLLSSLNKPDKSEMIKKFDEEKQQE 960
Query: 3188 CEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSM 3367
E+ K + I + E++KL L + ++ NL +
Sbjct: 961 LEKTKTAKSELENQIHQMSIEKQKLTINLEKLENDKLNLQNIVNDYQSKNSEMTKNLQDL 1020
Query: 3368 Q---LELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEG 3538
Q +L+N ++L N+ +++ + ++ K+E ++L TQ +E K +E L
Sbjct: 1021 QKKNFDLQNLYDDLINKTNEQNHRNEKSLENKDEEIKQLKDTQHELESKIESQLESLQNN 1080
Query: 3539 EQKILLLESS----QSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVA 3706
E+KI LLES + EQ ++ ++ L + +L+ L+ +E ++K +LE
Sbjct: 1081 EEKIKLLESKIEDLEEEKLEQNNINQNKISELEHKIEELQNNSLN-NDENENKISELENQ 1139
Query: 3707 MTETKFLKEKLLVSDENL-KEKDLQLRAFEIANSEK 3811
+ E + EKL E L KEK+ + E +S K
Sbjct: 1140 VQEYQETIEKLRKQIEELEKEKENKADTSETESSTK 1175
Score = 78.2 bits (191), Expect = 3e-11
Identities = 181/911 (19%), Positives = 361/911 (39%), Gaps = 71/911 (7%)
Frame = +2
Query: 272 IEVEDGGLDTRKS-LET---KIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLL-- 433
+E E L KS LET K+++ +E ++ E + + N +L + N + L
Sbjct: 782 LEEEISNLQNEKSVLETENEKLSKQIEELQEKEKSS----QEENEELSKQNEEMKEKLSK 837
Query: 434 ------EDIRNTKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLN 595
E+ ++ +E L N + + N + + +E + K+ + L
Sbjct: 838 QDKEFEEEKEKLNAKIEKIEKDLSDGNNEKETLTNDFED-EVKRIEEDIDNKNKQIKQLE 896
Query: 596 KKIEDLNHKIWSLE---ETLQYKEEVILSSHETIS-------------ERDRLLKDFIHE 727
++ LN ++ L+ E LQ +++V+ + + I ++ ++K F E
Sbjct: 897 EEKSQLNEEMNKLQLNNEFLQKQKDVVETENNKIKKDFESLLSSLNKPDKSEMIKKFDEE 956
Query: 728 KDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSL--DCFRRDEI 901
K QQ ++T+ + +N++ M +EK + ++L K +E N Q++ D ++
Sbjct: 957 K---QQELEKTKTAKSELENQIHQMSIEKQKLTINLEK-LENDKLNLQNIVNDYQSKNSE 1012
Query: 902 EDQNIKEEIEKQI-VETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQA 1078
+N+++ +K ++ +Y I + E++ +EI+ LKD H E ++
Sbjct: 1013 MTKNLQDLQKKNFDLQNLYDDLINKTNEQNHRNEKSLENKDEEIKQLKDTQHELESKIES 1072
Query: 1079 EISKLSHT------LEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKN---SY 1231
++ L + LE I + E L I +N EL +I +L+N+ + + +
Sbjct: 1073 QLESLQNNEEKIKLLESKIEDLEEEKLEQNNINQNKISELEHKIEELQNNSLNNDENENK 1132
Query: 1232 IDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGK 1411
I L +++ KL++Q T ++ + +ELE+E
Sbjct: 1133 ISELENQVQEYQETIEKLRKQIEELEKEKENKADTSETESSTKIKELEDKIEELEKENDL 1192
Query: 1412 ISENLERISKLQ----KMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGS 1579
E I LQ K+NNE++ + + N
Sbjct: 1193 FQNEGESILDLQEEVTKLNNEISTLRQLTCKLEED-------------------NKTLKD 1233
Query: 1580 KLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEK 1759
EE I+ + +KE E D IS ++T LS E +K ++ +Q + I
Sbjct: 1234 GSEEDEKLISSLRKQLKEKEKEKESENDNISQIKTNLSVLSKENDKLKREMQMKDDKISD 1293
Query: 1760 L--VNDSLHEVDSAFCS---LNSRFYSLIHKVDNSGETLRAFVKN----------IQNQV 1894
L + SL + S + + +I K D + ++ +KN +Q+Q+
Sbjct: 1294 LSILTSSLRTENEHLKSDLDIKKKEIDIIKKNDETVQSALDQIKNSNSSDKTIKSLQSQL 1353
Query: 1895 AV------SQEQHIEHQCKEELEGHIADL--VLNDFSNDILSWSRRKEEAVVHDDEFDAE 2050
+V + E+ +E KE+ E IA L V+N+ I S ++E F+
Sbjct: 1354 SVCCMQKETLEKELEDMRKEDQET-IAQLKQVVNELQTKISLSSPQRE--------FNQM 1404
Query: 2051 RIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKS 2230
+I +LK + +E L+ E L N V I+E + D+ K+
Sbjct: 1405 KI----QLKQKQEQIERLRQEN--DELQNKVNY-----------IKEKAKNDIKDIIKKT 1447
Query: 2231 RALRRHSTGQAFREPP--KPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLR 2404
+ S+ + E + + L K+ E + +K+L +I E +
Sbjct: 1448 QVPEVKSSEKTLSEVSDLRRKVLMFDKENQKLTEQNNELKKQLQSISVLEQRE------- 1500
Query: 2405 NWPKEQLLGHFKQSFAGLKREYELELQRKTEEIY-DLKRLLLNEKNGLHAXXXXXXXXXX 2581
KE + K + + E E +L +K+EE D+++ L+
Sbjct: 1501 ---KEYITQISKLTKKTKELEEENKLIKKSEEDKTDIEQRYLDTVTNTSKMSHE------ 1551
Query: 2582 XXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEI-KEKDSNSKVL 2758
+ + + Q+ L + +Q K + + L++ +DS LKE+ +E+ N +++
Sbjct: 1552 --IQTLNETINTLTQKLSQLKKQHLQEKKEMQIEVSTLKTSLDSSLKELEEERKHNMQLI 1609
Query: 2759 AEKLSDALKKS 2791
+ ++ +K S
Sbjct: 1610 KDSKTNIVKLS 1620
>ref|XP_001014708.1| DNA-directed RNA polymerase, omega subunit family protein
[Tetrahymena thermophila]
Length = 4331
Score = 138 bits (348), Expect = 2e-29
Identities = 269/1299 (20%), Positives = 539/1299 (41%), Gaps = 131/1299 (10%)
Frame = +2
Query: 305 KSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGL 484
++LE ++ +E ++I + + L+N DL Q+ +E I N + L E
Sbjct: 2390 EALEERLTSKIEELKI-QNEQNQELQNKLEDLIQETQQK---IEKI-NDQHQLGLQEKDN 2444
Query: 485 YVSNVVSDA------VLNGVVSAQE--EEFKEALAAKDSENFLLNKKIEDLNHKIWSLEE 640
Y ++ +LN +S ++ EEF + + ++ + F +I N + ++
Sbjct: 2445 YYQELLKQKEQEQMNLLNDQLSEKQKQEEFMKCMQQQE-QRFQEQLQITQQNAQDLVQQK 2503
Query: 641 TLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHM---VLE 811
+ YKE +I E + +R K IHEK+ ++Q + E+K+ + NE+ ++ +L+
Sbjct: 2504 EIHYKE-IISMKDEDLMKR----KQEIHEKEEIKQ---QLEEKIFNLQNELQNLKEEILQ 2555
Query: 812 KDNII-------LSLHKQIE---------LQSQNTQSLDCFRRDEIEDQNIKEEIEKQIV 943
K+N I +SL+KQI+ LQ Q +L R+ NIK++ + Q+
Sbjct: 2556 KNNDIHRQEDIQISLNKQIDELKKNLQESLQKQEESALILLEREN----NIKQQEQAQVS 2611
Query: 944 ETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMN 1123
+ + Q++ +E++ + E A + + + E K +S EI+ L++TL+E++
Sbjct: 2612 QNKEIDQLKNKLQENEQKQNEMALILQDKEHVMKEQEEKLISLNNEINNLNNTLKENLQK 2671
Query: 1124 SNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECN-KLQEQXX 1300
+ L E E EL +QI QL++ + S I L S E N KL +Q
Sbjct: 2672 VSERDLVLLE-KEKDISELQEQIVQLQDKISSSELQITQLQSNSINKEEELNSKLAQQ-- 2728
Query: 1301 XXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSK 1480
AS KL ++L+ + ++ ++++ + +L K+N +++
Sbjct: 2729 -----------------ASDNQNQLKLIEDLKNQIQELEKSIDSLEQL-KINELQDQKNN 2770
Query: 1481 SQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVID----KKEAEV 1648
+ SI + +EEL QI F ++ + + ++
Sbjct: 2771 YELSIKNFEEEIKKIKQDYETKIQENSQI-----IEELNVQIKSFEQQLELQKIQNKQQL 2825
Query: 1649 SGHLDTISSLQTVLSNQKFEIEKSQ--KVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFY 1822
S H + + LQ +N+K E++K K SF S IE+L N ++++ F +
Sbjct: 2826 SDHEEYVKQLQEEFNNKKLELQKEYETKAGASF-SEIEQLHNQKINKMQEEFEEKHKNMK 2884
Query: 1823 -SLIHKVDNSGETLRAFVK-----NIQNQV-------AVSQEQHIEHQCKEELEGHIADL 1963
SL ++ E L A ++ N+Q Q A Q+Q I + E L+ ++
Sbjct: 2885 DSLQSEIKKLQEDLEAQIQENKKLNLQIQELDSELLNAKEQKQKISQEVDETLQKNVE-- 2942
Query: 1964 VLNDFS-------NDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAV 2122
LND N++LS ++ EE H DE I LL E + LE ++ + V
Sbjct: 2943 -LNDKIQQQIEQINNLLS--KQNEERQSHQDE-----INLLQE--KFEKQLEEVQKQNQV 2992
Query: 2123 KSLSNNVGVSTKGIHYFSQLIQEGKDG----------EASDVQGKSRALRRHSTGQAFRE 2272
K ++ V QL+Q ++ + S VQ ++ L + + E
Sbjct: 2993 KLEQSHSEVEQSHQSEIQQLLQNQQEAILKLKNELTEQLSKVQQENDLLEKQLRAKESEE 3052
Query: 2273 PPKPEDLYTTYS-----EGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHF 2437
+ L Y E +V K + + FE N K+ ++
Sbjct: 3053 EQLNDKLSQQYDQIQEKESDLVSLKEENNKLIQKVQNFEKIKNELVEENNQLKQNIVELE 3112
Query: 2438 KQSF---AGLKR-------------EYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXX 2569
S A L++ ++ LQ+K +I +L +L +
Sbjct: 3113 NSSAEISANLEKLIQENQDKEQQIYDFNDNLQQKESQIQELNSKILQIEEKYQTQIQELE 3172
Query: 2570 XXXXXXVAEITGKF----------EKVLQENKLLPVEEVQR-----YKMLCVLKEELQSK 2704
+ ++ KF EK QE KL ++E Y+ L + + +QS+
Sbjct: 3173 KNHQVKIKDLADKFTVCEDTLVLQEKQFQE-KLSNLQEKYNLEQTNYESLQIDHQNIQSQ 3231
Query: 2705 IDSLLKEIKEKDSNSKVLAEKLS---DALKKSADHAQRES-HLLKHIADLEAGITDREIM 2872
++ L +E++++ + +L++K D + +++ + Q+++ L K + +A I +
Sbjct: 3232 LNLLQEELQKQIEGNHILSQKQQEEKDLVSENSQNLQQQNLDLHKENEESKAKIQQMKEK 3291
Query: 2873 TSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKE 3052
S + + + + + +E + + +++ + +K+ ++K+ L ++ E+ ++
Sbjct: 3292 LSQLEEQIEKVNDDKQKSQEENEKMRIEKETEIEEKEKEIQKLKVQIQDLEGVMEEQTQQ 3351
Query: 3053 HKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQEC-------------- 3190
+ +EK K++ + ++ + +++EE+K L L EC
Sbjct: 3352 IQTANVEVEKFKKDLDERYNQIAFLEDILKQLEEEKNNLQNTLNECDNALIQERNERATV 3411
Query: 3191 EELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQ 3370
EE N + +K +++ RE+ ++ ++L+ SS S
Sbjct: 3412 EETINLLNDKITNLQIEREDNLEIIEKLKADLLQSQPQKQNSSPIKLSLPQTSSQAGSSS 3471
Query: 3371 LELRNY------NEELKNEIEKKSTDIDLLIKEKEEL---NERLAYTQKAMEQKEAVLVE 3523
+ + N EL ++I + +I +EKEE+ N++L KE L++
Sbjct: 3472 AQKQQIDQLTFANAELLDQINELELEIKEYQREKEEILDENDKLT--------KEIELLK 3523
Query: 3524 KLFEGEQ----KILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKER 3691
L +GEQ K+ L+E + +E L L +E K++ S E+ +
Sbjct: 3524 GL-QGEQPVNRKVELIEDREIMEQE--------LQQLNQEQQVQKQKRASLQNEMSDLKS 3574
Query: 3692 DLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSE 3808
LE + + L+E+++ + L EK+ L+ ++AN +
Sbjct: 3575 ILEQNIVVIQTLEEEIVNYKKKLAEKEESLQLKQVANDQ 3613
Score = 122 bits (306), Expect = 1e-24
Identities = 240/1178 (20%), Positives = 483/1178 (41%), Gaps = 87/1178 (7%)
Frame = +2
Query: 539 EEEFKEALAAKDSENFLLNKKI-------EDLNHKIWSLEETLQYKEEVILSSHETISER 697
+ E E L+ EN LL K++ E LN K+ + +Q KE ++S E E
Sbjct: 3024 KNELTEQLSKVQQENDLLEKQLRAKESEEEQLNDKLSQQYDQIQEKESDLVSLKE---EN 3080
Query: 698 DRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDN----IILSLHKQIELQSQN 865
++L++ Q ++ + +L +N++ ++E +N I +L K I+
Sbjct: 3081 NKLIQKV--------QNFEKIKNELVEENNQLKQNIVELENSSAEISANLEKLIQENQDK 3132
Query: 866 TQSLDCFRRDEIEDQNIKEEIEKQI--VETIYVTQIQELGEEHDLLRLESAKYQDEIQSL 1039
Q + F + + ++ +E+ +I +E Y TQIQEL + H + + A D+
Sbjct: 3133 EQQIYDFNDNLQQKESQIQELNSKILQIEEKYQTQIQELEKNHQVKIKDLA---DKFTVC 3189
Query: 1040 KDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYS 1219
+D +E Q ++S L + ++ +N ESL ++N +L +L+ +
Sbjct: 3190 EDTLVLQEKQFQEKLSNLQE--KYNLEQTNYESLQID--HQNIQSQLNLLQEELQKQIEG 3245
Query: 1220 KNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEE 1399
+ D +S LQ+Q L E EE
Sbjct: 3246 NHILSQKQQEEKDLVSENSQNLQQQNLD-------------------------LHKENEE 3280
Query: 1400 ERGKISENLERISKLQKMN---NELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMA 1570
+ KI + E++S+L++ N+ ++S+ +N V
Sbjct: 3281 SKAKIQQMKEKLSQLEEQIEKVNDDKQKSQEENEKMRIEKETEIEEKEKEIQKLKVQIQD 3340
Query: 1571 FGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESH 1750
+EE T QI N ++K + ++ + I+ L+ +L + E Q L ++
Sbjct: 3341 LEGVMEEQTQQIQTANVEVEKFKKDLDERYNQIAFLEDILKQLEEEKNNLQNTLNECDNA 3400
Query: 1751 IEKLVNDSLHEVDSAFCSLNSRFYSL-IHKVDNSG--ETLRAFVKNIQNQVAVSQ----- 1906
+ + N+ V+ LN + +L I + DN E L+A + Q Q S
Sbjct: 3401 LIQERNERA-TVEETINLLNDKITNLQIEREDNLEIIEKLKADLLQSQPQKQNSSPIKLS 3459
Query: 1907 ---------EQHIEHQCKEELEGHIADLV--LNDFSNDILSWSRRKEEAVVHDDEFDAE- 2050
+ Q ++L A+L+ +N+ +I + R KEE + +D+ E
Sbjct: 3460 LPQTSSQAGSSSAQKQQIDQLTFANAELLDQINELELEIKEYQREKEEILDENDKLTKEI 3519
Query: 2051 --------------RIALLNELKSLHQDLELLKAEEAVK-----SLSNNVGVSTKGIHYF 2173
++ L+ + + + Q+L+ L E+ V+ SL N + K I
Sbjct: 3520 ELLKGLQGEQPVNRKVELIEDREIMEQELQQLNQEQQVQKQKRASLQNEMS-DLKSILEQ 3578
Query: 2174 SQLIQEGKDGEASDVQGK------SRALRRHSTGQAFREPPK-PEDLYTTYSEGKIVEPH 2332
+ ++ + + E + + K S L++ + Q K E+L + E + ++
Sbjct: 3579 NIVVIQTLEEEIVNYKKKLAEKEESLQLKQVANDQNSERFSKIEEELDISKHENQNLKNQ 3638
Query: 2333 PTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDL 2512
T+ ++ L+ + +S L + F K + E+ ++ + D
Sbjct: 3639 ITQLEQQLSEKDYHLEQQHNSICE-------LSAMIEKFENQKSDAEV-IENLKQMHTDK 3690
Query: 2513 KRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEE 2692
+ L+ E N A + I E ++NK + E Q++K L + E
Sbjct: 3691 MKKLVKEHNEALASKDKEIKQLTSLIKNINEVNE---EQNKTISSFE-QKHKSLIAERFE 3746
Query: 2693 LQSKIDSLLKEIKEKDSNSKVLAEK-------LSDALKKSADHAQRESHLLKHIADLEAG 2851
LQ+ I L +++K+ ++ +K D LK+ + Q+ L + ++ +
Sbjct: 3747 LQNTIQELKDSLQQKEEQIQLFEKKNDEMQAETQDTLKQQKELNQQLETLKEKLSHFQTN 3806
Query: 2852 ITDREIMTSVCSDVL----TALFVEMVREKEFSLSLATKEQETVN-QKQMSLRKMLEDKD 3016
+T+ S D + + + +RE + + T+E+E + +K++ + ++ D
Sbjct: 3807 MTNPSEKLSSEEDAIGYQSAKRYEDQIRELQEEIQKRTREKEQLRTEKEIECIGLKQEMD 3866
Query: 3017 KL--LCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQEC 3190
+L LC E +E ++Q L+++ E+ +N+ + ++E+EK +E K+ L++A QE
Sbjct: 3867 RLQKLCDRLTEQEESQKQ---LKEVLEDHKNDA--IQKLNKEKEKNKEMKKYLEEAHQEI 3921
Query: 3191 EELKNDIQNKHSDIDSLREEQEKLNK---QLRCMXXXXXXXXXXXXXXXXXXXXISSNLD 3361
E+L+ + KH Q KL+ + + +
Sbjct: 3922 EQLRKNRHEKHEKDGDNDHHQRKLSSKEDEEDAVYQKYKELEEKLTKILTEKKQLEDQNK 3981
Query: 3362 SMQLELRN---YNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLF 3532
S+Q EL+N Y+ E E + K L+K K+EL +++ +EQ+ + +E+L
Sbjct: 3982 SLQSELQNKSIYDNESFYEFQNK------LLKSKQELEDKI-----ELEQQLEICLERLV 4030
Query: 3533 -EGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAM 3709
EGE ++ L +S+ + N+L + + K+F E+ SK +D +
Sbjct: 4031 NEGELDLMDLNNSR------------ICNNLVKIQQNF-KEFYQFKEKFGSKHQDELKKI 4077
Query: 3710 TETKFLKEKLLVSDENLKE----KDLQLRAFEIANSEK 3811
+T + +L+V ++ +KE K++ L+ + NSE+
Sbjct: 4078 AQT--YQSQLIVKEKQIKELQKYKEMYLK--PVLNSEE 4111
Score = 121 bits (304), Expect = 2e-24
Identities = 243/1209 (20%), Positives = 497/1209 (41%), Gaps = 77/1209 (6%)
Frame = +2
Query: 428 LLEDIRNTKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIE 607
L++ N ++L E L ++N D + N + Q + + ++ E N +
Sbjct: 1674 LIQMQENIEELKQNYEQQLQINN---DQISNSNQNFQIQ-IENLQKLREEEEKYQNSNLS 1729
Query: 608 DLNHKIWSLEETLQYKEE----------VILSSHET-ISERDRLLKDFIHEKDLMQQRAQ 754
DLN++I L + L KEE VI S+E I E ++ +K+ +Q R
Sbjct: 1730 DLNNQIQELNQALSQKEEELQEINMKQSVIQQSYENKIKELEQNCLQIFEQKEELQIRIS 1789
Query: 755 ETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEK 934
+ ++++A + +EK K E Q+++T+SL +N +E+E
Sbjct: 1790 QLDEEIADLKS------VEK--------KSFEEQTESTKSL----------ENTIKELEN 1825
Query: 935 QIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEES 1114
QI Q+ E ++ + E Q++I + +DE ++ + +++ ++ E
Sbjct: 1826 QI------NQLNEQNKKQN----EQLVQQNQIIAQQDEQINEQTEQITQLNLQNNQQNEQ 1875
Query: 1115 IMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQ 1294
I+ N + + + + ++I++L + KN I+ L +I L N+L Q
Sbjct: 1876 IIEQNQQII----SQNDKIDQQNEEINELNEQIKLKNEQINKLDEQIKQLEEVLNQLNSQ 1931
Query: 1295 XXXXXXXXXXXXXXXXTLKASMEMQ-------CSKLKD---ELEEERGKISENLERISKL 1444
LK E Q KLK +L+E+ I EN + IS+L
Sbjct: 1932 IKQKDLDLEYKNQLFDNLKLQYEEQGQLLHNHQEKLKSNTIKLDEQNSMIEENQQLISQL 1991
Query: 1445 Q-KMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLE--ELTDQINIF 1615
+ ++ N L E S S N + + K E L + +
Sbjct: 1992 RTQLENSLKENSHSLNEQENSINQLNCELLQMGQDKQQLQGLIHQLKEENSNLNEDLKQK 2051
Query: 1616 NSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKL-VNDSLHEVD- 1789
++I + + + D L+ L+NQ ++K Q+ +QS + E+L + L+E
Sbjct: 2052 LNIISESQQLIKEKSDIAEELKQNLTNQ---LQKQQEYIQSIQQLQEELKESQELNEKHI 2108
Query: 1790 SAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVL 1969
+ L + K+DN E ++ + + + Q ++ +Q ++ Q + + + +
Sbjct: 2109 NKIKQLEEQLQQNTEKIDNLEENIQKLISD-KEQFEINNKQ-LQDQINQ--QDQLIESFE 2164
Query: 1970 NDFSNDILSWSRRKEEAVVHDDEF-DAERIALLNELKSLHQDLELLKAEEAVKSLSNNVG 2146
F + S S+ K +A ++ +A++ +L E ++L Q LE +E + SL +
Sbjct: 2165 EQFQKQLDSESKLKLQATNLEESLKEAQQKEILLE-QNLTQQLESKNSE--IDSLVQKIK 2221
Query: 2147 VSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVE 2326
+ + I + +++ K+ Q + +T Q ++ +DL S K+VE
Sbjct: 2222 QNEEEIVVLNNNLEQIKESHNEITQ------KLENTEQLLKQ--SEQDL---NSSQKLVE 2270
Query: 2327 PHPTEEKKL-----LAILAFETADA---SDSPLRNWPKEQLLGHFKQSFAGLKREYELEL 2482
+K+ AI +E S N K+ L F S A ++ +L+L
Sbjct: 2271 QLEQNLEKINSENTHAIQEYEEKIKQLNSQVESLNNEKDSLASQFMDSDA-QNQDIQLKL 2329
Query: 2483 QRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQR 2662
Q E L+ + EK + E ++ Q +LL E QR
Sbjct: 2330 QSLQTE---LESKIEKEKQ------------QAALIKEKQNLIDEKEQAIQLLSTEYEQR 2374
Query: 2663 YKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADL 2842
+ + ++LQ K+++L + + K K+ E+ + K D Q ++ I D
Sbjct: 2375 EEQSQQVNKQLQHKLEALEERLTSKIEELKIQNEQNQELQNKLEDLIQETQQKIEKINDQ 2434
Query: 2843 -EAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDK 3019
+ G+ +++ + E++++KE +Q + QKQ K ++ +++
Sbjct: 2435 HQLGLQEKD-----------NYYQELLKQKEQEQMNLLNDQLSEKQKQEEFMKCMQQQEQ 2483
Query: 3020 LLCLVGEENKEHKRQIAILEKL--KEETENNPGRVFLQSEEREKIEEQKRVLDQAL---- 3181
+ +++ + + +++ KE + + +E + EE K+ L++ +
Sbjct: 2484 RFQEQLQITQQNAQDLVQQKEIHYKEIISMKDEDLMKRKQEIHEKEEIKQQLEEKIFNLQ 2543
Query: 3182 QECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLD 3361
E + LK +I K++DI + Q LNKQ+ + +N+
Sbjct: 2544 NELQNLKEEILQKNNDIHRQEDIQISLNKQIDELKKNLQESLQKQEESALILLERENNIK 2603
Query: 3362 SMQLELRNYNEE---LKNEI---EKKSTDIDLLIKEKE------------------ELNE 3469
+ + N+E LKN++ E+K ++ L++++KE LN
Sbjct: 2604 QQEQAQVSQNKEIDQLKNKLQENEQKQNEMALILQDKEHVMKEQEEKLISLNNEINNLNN 2663
Query: 3470 RLAYTQKAMEQKEAVLVEK---LFEGEQKILLLESSQSATREQ--------TEKYRDLLN 3616
L + + +++ VL+EK + E +++I+ L+ S++ Q K +L +
Sbjct: 2664 TLKENLQKVSERDLVLLEKEKDISELQEQIVQLQDKISSSELQITQLQSNSINKEEELNS 2723
Query: 3617 SLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEI 3796
L ++ +D + Q L E+L+++ ++LE ++ + LK L +N E ++ EI
Sbjct: 2724 KLAQQASDNQNQ-LKLIEDLKNQIQELEKSIDSLEQLKINELQDQKNNYELSIKNFEEEI 2782
Query: 3797 ANSEKQYQT 3823
++ Y+T
Sbjct: 2783 KKIKQDYET 2791
Score = 118 bits (296), Expect = 2e-23
Identities = 233/1268 (18%), Positives = 542/1268 (42%), Gaps = 112/1268 (8%)
Frame = +2
Query: 314 ETKIAETLERME----IHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESG 481
+ +I + E+ME + E + KNM L Q N + + D + K+ ++ ++
Sbjct: 1371 QREIKKCKEKMEEIKKMQEKVNLDQQKNMQDQLAQKNKLIEMMKNDSLDDKEEIELLKQE 1430
Query: 482 LYVSNVVSDAVLNGVVSA--QEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLE----ET 643
+ A + +S+ QE ++KE K+ E K I+ N KI +E +
Sbjct: 1431 IEELKQQLQATQSKPLSSSRQESQYKE-FQQKEEE---FKKLIKQQNEKIAKMEQDCLQK 1486
Query: 644 LQYKEEV---------ILSSH-ETISERDRLLKDFIHEKDL-------MQQRA----QET 760
++++EE+ L SH ++ ++++ + I+++D+ QQ + QE
Sbjct: 1487 MEFEEEIARLQQELQSALDSHNDSGKKQNQSIDQIINDQDIDGLQNKRNQQNSFEDLQER 1546
Query: 761 EQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDC--------FRRDEIEDQNI 916
++L +N++ + E+D + + + I+ + T L ++++I+ + I
Sbjct: 1547 VKELEEENNDLREIQNERDCLQQQIQEIIDKNKEETDQLQSTVRLLTQQIQKNQIDSEKI 1606
Query: 917 KEEIEKQIVE-TIYVTQ----IQELGEEHDLLRLESAK-----------YQDEIQSLKDE 1048
+ ++ +I T ++ Q IQ+ EHD +E + +D+I+ + D+
Sbjct: 1607 IQNLQNEIGSMTQFIKQQEQLIQQQNAEHDQKEIEFRQIIKEKDNYIFTQRDQIEQITDQ 1666
Query: 1049 CHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLR----NDMY 1216
K ++ ++ +EE N + + N+ + QI L+ +
Sbjct: 1667 I----KEKNNQLIQMQENIEELKQNYEQQLQINNDQISNSNQNFQIQIENLQKLREEEEK 1722
Query: 1217 SKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELE 1396
+NS + L ++I L+ ++ +E+ +E C ++ ++ E
Sbjct: 1723 YQNSNLSDLNNQIQELNQALSQKEEELQEINMKQSVIQQSYENKIKELEQNCLQIFEQKE 1782
Query: 1397 EERGKISENLERISKLQKMNNE-LAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAF 1573
E + +IS+ E I+ L+ + + E+++S S+ +N
Sbjct: 1783 ELQIRISQLDEEIADLKSVEKKSFEEQTESTKSLENTIKELENQINQ--------LNEQN 1834
Query: 1574 GSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFE--IEKSQKVLQSFES 1747
+ E+L Q N +I +++ +++ + I+ L + +NQ+ E IE++Q+++ +
Sbjct: 1835 KKQNEQLVQQ----NQIIAQQDEQINEQTEQITQL-NLQNNQQNEQIIEQNQQIISQNDK 1889
Query: 1748 HIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQ 1927
++ N+ ++E++ N + I+K+D + L + + +Q+ +++ ++ +
Sbjct: 1890 IDQQ--NEEINELNEQIKLKNEQ----INKLDEQIKQLEEVLNQLNSQI---KQKDLDLE 1940
Query: 1928 CKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELL- 2104
K +L F N L + + + H ++ + I L + + ++ +L+
Sbjct: 1941 YKNQL-----------FDNLKLQYEEQGQLLHNHQEKLKSNTIKLDEQNSMIEENQQLIS 1989
Query: 2105 ----KAEEAVKSLSNNVGVSTKGIHYFS-QLIQEGKDGEASDVQGKSRALRRHSTGQAFR 2269
+ E ++K S+++ I+ + +L+Q G+D + +QG L+ ++
Sbjct: 1990 QLRTQLENSLKENSHSLNEQENSINQLNCELLQMGQDKQ--QLQGLIHQLKEENSN--LN 2045
Query: 2270 EPPKPEDLYTTYSEGKIVEPHPTEE--KKLLAILAFETADASDSPLRNWPKEQLLGHFKQ 2443
E K + + S+ I E E K+ L + + S + + + +
Sbjct: 2046 EDLKQKLNIISESQQLIKEKSDIAEELKQNLTNQLQKQQEYIQSIQQLQEELKESQELNE 2105
Query: 2444 SFAGLKREYELELQRKTEEIYDLK---RLLLNEKNGL---HAXXXXXXXXXXXXVAEITG 2605
++ E +LQ+ TE+I +L+ + L+++K + +
Sbjct: 2106 KHINKIKQLEEQLQQNTEKIDNLEENIQKLISDKEQFEINNKQLQDQINQQDQLIESFEE 2165
Query: 2606 KFEKVLQENKLLPVE---------EVQRYKMLCV--LKEELQSK---IDSLLKEIKEKDS 2743
+F+K L L ++ E Q+ ++L L ++L+SK IDSL+++IK+ +
Sbjct: 2166 QFQKQLDSESKLKLQATNLEESLKEAQQKEILLEQNLTQQLESKNSEIDSLVQKIKQNEE 2225
Query: 2744 NSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVE--- 2914
VL L + + Q+ + + + E + + + L + E
Sbjct: 2226 EIVVLNNNLEQIKESHNEITQKLENTEQLLKQSEQDLNSSQKLVEQLEQNLEKINSENTH 2285
Query: 2915 MVREKEFSLSLATKEQETVNQKQMSLRKMLEDKD--------KLLCLVGE-ENK--EHKR 3061
++E E + + E++N ++ SL D D KL L E E+K + K+
Sbjct: 2286 AIQEYEEKIKQLNSQVESLNNEKDSLASQFMDSDAQNQDIQLKLQSLQTELESKIEKEKQ 2345
Query: 3062 QIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQ-ECEELKNDIQNKHSDIDS 3238
Q A++++ + + + L S E E+ EEQ + +++ LQ + E L+ + +K ++
Sbjct: 2346 QAALIKEKQNLIDEKEQAIQLLSTEYEQREEQSQQVNKQLQHKLEALEERLTSKIEELKI 2405
Query: 3239 LREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEK 3418
E+ ++L +L + + Q ++ N++ + +++
Sbjct: 2406 QNEQNQELQNKLEDL------------------------IQETQQKIEKINDQHQLGLQE 2441
Query: 3419 KSTDIDLLIKEKEE-----LNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATR 3583
K L+K+KE+ LN++L+ QK E + + ++ EQ + +++Q +
Sbjct: 2442 KDNYYQELLKQKEQEQMNLLNDQLSEKQKQEEFMKCMQQQEQRFQEQLQITQQNAQDLVQ 2501
Query: 3584 EQTEKYRDLLNSLTEEHADLKKQFLSATEEL-QSKERDLEVAMTETKFLKEKLLVSDENL 3760
++ Y++++ S+ +E +KQ + EE+ Q E + E + LKE++L + ++
Sbjct: 2502 QKEIHYKEII-SMKDEDLMKRKQEIHEKEEIKQQLEEKIFNLQNELQNLKEEILQKNNDI 2560
Query: 3761 -KEKDLQL 3781
+++D+Q+
Sbjct: 2561 HRQEDIQI 2568
Score = 117 bits (292), Expect = 5e-23
Identities = 241/1294 (18%), Positives = 514/1294 (39%), Gaps = 126/1294 (9%)
Frame = +2
Query: 251 DISVTSFIEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGL 430
D + SF E LD+ L+ + E ++ + +N+ L N + L
Sbjct: 2157 DQLIESFEEQFQKQLDSESKLKLQATNLEESLKEAQQKEILLEQNLTQQLESKNSEIDSL 2216
Query: 431 LEDIRNTKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIED 610
++ I+ ++ + VLN + +E E ++ LL + +D
Sbjct: 2217 VQKIKQNEEEI---------------VVLNNNLEQIKESHNEITQKLENTEQLLKQSEQD 2261
Query: 611 LNHK---IWSLEETL------------QYKEEV--ILSSHETI-SERDRLLKDFIHEKDL 736
LN + LE+ L +Y+E++ + S E++ +E+D L F+ + D
Sbjct: 2262 LNSSQKLVEQLEQNLEKINSENTHAIQEYEEKIKQLNSQVESLNNEKDSLASQFM-DSDA 2320
Query: 737 MQQRAQ--------------ETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQS 874
Q Q E E++ A+ E +++ EK+ I L + E + + +Q
Sbjct: 2321 QNQDIQLKLQSLQTELESKIEKEKQQAALIKEKQNLIDEKEQAIQLLSTEYEQREEQSQQ 2380
Query: 875 LD--------------CFRRDEIEDQNIK-EEIEKQIVETIYVTQ--IQELGEEHDLLRL 1003
++ + +E++ QN + +E++ ++ + I TQ I+++ ++H L
Sbjct: 2381 VNKQLQHKLEALEERLTSKIEELKIQNEQNQELQNKLEDLIQETQQKIEKINDQHQLGLQ 2440
Query: 1004 ESAKYQDEIQSLKDE-------CHAKEMSKQAEISKLSHTLEE------SIMNSNLESLF 1144
E Y E+ K++ E KQ E K E+ I N + L
Sbjct: 2441 EKDNYYQELLKQKEQEQMNLLNDQLSEKQKQEEFMKCMQQQEQRFQEQLQITQQNAQDLV 2500
Query: 1145 -TAEIYENTFRELGDQ-ISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXX 1318
EI+ + D+ + + + +++ K L +I L +E L+E+
Sbjct: 2501 QQKEIHYKEIISMKDEDLMKRKQEIHEKEEIKQQLEEKIFNLQNELQNLKEE----ILQK 2556
Query: 1319 XXXXXXXXTLKASMEMQCSKLKDELEEERGKISEN----LERIS--------------KL 1444
++ S+ Q +LK L+E K E+ LER + ++
Sbjct: 2557 NNDIHRQEDIQISLNKQIDELKKNLQESLQKQEESALILLERENNIKQQEQAQVSQNKEI 2616
Query: 1445 QKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMA--FGSKLEELTDQINIFN 1618
++ N+L E + QN + + N + L+E +++ +
Sbjct: 2617 DQLKNKLQENEQKQNEMALILQDKEHVMKEQEEKLISLNNEINNLNNTLKENLQKVSERD 2676
Query: 1619 SVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIE-------------- 1756
V+ +KE ++S + I LQ +S+ + +I + Q + E +
Sbjct: 2677 LVLLEKEKDISELQEQIVQLQDKISSSELQITQLQSNSINKEEELNSKLAQQASDNQNQL 2736
Query: 1757 KLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQV-AVSQEQHIEHQCK 1933
KL+ D +++ S++S I+++ + +KN + ++ + Q+ + Q
Sbjct: 2737 KLIEDLKNQIQELEKSIDSLEQLKINELQDQKNNYELSIKNFEEEIKKIKQDYETKIQEN 2796
Query: 1934 EELEGHIADLVLNDFSNDI-LSWSRRKEEAVVHDD------------------EFDAERI 2056
++ + ++ + F + L + K++ H++ E++ +
Sbjct: 2797 SQIIEEL-NVQIKSFEQQLELQKIQNKQQLSDHEEYVKQLQEEFNNKKLELQKEYETKAG 2855
Query: 2057 ALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRA 2236
A +E++ LH ++ K +E + N+ S + S++ + +D EA + K
Sbjct: 2856 ASFSEIEQLHNQ-KINKMQEEFEEKHKNMKDSLQ-----SEIKKLQEDLEAQIQENKKLN 2909
Query: 2237 LR-RHSTGQAFREPPKPEDLYTTYSE--GKIVEPHPTEEKKLLAILAFETADASDSPLRN 2407
L+ + + + + + E K VE + ++++ I + +
Sbjct: 2910 LQIQELDSELLNAKEQKQKISQEVDETLQKNVELNDKIQQQIEQINNLLSKQNEERQSHQ 2969
Query: 2408 WPKEQLLGHFKQSFAGLKREYELELQRKTEEI-----YDLKRLLLNEKNGLHAXXXXXXX 2572
L F++ ++++ +++L++ E+ ++++LL N++ +
Sbjct: 2970 DEINLLQEKFEKQLEEVQKQNQVKLEQSHSEVEQSHQSEIQQLLQNQQEAI--------- 3020
Query: 2573 XXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSK 2752
E+T + KV QEN LL E+ R K +E+L K+ +I+EK+S+
Sbjct: 3021 --LKLKNELTEQLSKVQQENDLL--EKQLRAKE--SEEEQLNDKLSQQYDQIQEKESDLV 3074
Query: 2753 VLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKE 2932
L E+ + ++K + + ++ L++ L+ I + E ++ S L L E +++
Sbjct: 3075 SLKEENNKLIQKVQNFEKIKNELVEENNQLKQNIVELENSSAEISANLEKLIQENQDKEQ 3134
Query: 2933 FSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPG 3112
Q+ +Q Q K+L+ ++K + E K H Q+ I + + T
Sbjct: 3135 QIYDFNDNLQQKESQIQELNSKILQIEEKYQTQIQELEKNH--QVKIKDLADKFTVCEDT 3192
Query: 3113 RVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXX 3292
V + + +EK+ + + E L+ D QN S ++ L QE+L KQ+
Sbjct: 3193 LVLQEKQFQEKLSNLQEKYNLEQTNYESLQIDHQNIQSQLNLL---QEELQKQIE----G 3245
Query: 3293 XXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNER 3472
S NL L+L NEE K +I++ + L ++ E++N+
Sbjct: 3246 NHILSQKQQEEKDLVSENSQNLQQQNLDLHKENEESKAKIQQMKEKLSQLEEQIEKVNDD 3305
Query: 3473 LAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQ 3652
QK+ E+ E + +EK E E+K ++ +K + + L + +Q
Sbjct: 3306 ---KQKSQEENEKMRIEKETEIEEK-----------EKEIQKLKVQIQDLEGVMEEQTQQ 3351
Query: 3653 FLSATEELQSKERDLEVAMTETKFLKEKLLVSDE 3754
+A E++ ++DL+ + FL++ L +E
Sbjct: 3352 IQTANVEVEKFKKDLDERYNQIAFLEDILKQLEE 3385
Score = 82.8 bits (203), Expect = 1e-12
Identities = 238/1191 (19%), Positives = 473/1191 (39%), Gaps = 108/1191 (9%)
Frame = +2
Query: 575 SENFLLNKKIEDLNHKIWSLEETLQYKEEVI--------------LSSHETISERDRLLK 712
+EN +L ++ E L KI E+ ++ K+ ++ + + + E ++ L+
Sbjct: 689 NENRMLKQENEYLKLKIERCEKEIKEKKRIVEDNDAYYKKLFEEKVEGIQVLREENKQLQ 748
Query: 713 DFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRR 892
IH +L ++ QKL ++ EKD+ +K+++ Q Q + +D R
Sbjct: 749 LQIHNLELKSYDKKKNLQKL-------YRIITEKDDE----NKKLKYQLQQKEQID---R 794
Query: 893 DEIED--QNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEI---QSLKDECHA 1057
+ + Q+I+E++ +++ +++ + +E + L+ + D I + ++ E
Sbjct: 795 ESLNQAIQSIEEQLNQKM--QLFIEDLAY--KERIIENLQVNLFYDNIIQNEKMRGEQIN 850
Query: 1058 KEMSKQAEISK-LSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRN--DMYSKNS 1228
Q E + +S L E + E L + N + + G++ Q +N D+
Sbjct: 851 NVFQNQQETEQPISDKLIE--LRQKREDLLSILQNNNNYDQYGNENEQQQNLNDIKELLG 908
Query: 1229 YIDS-LASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDEL---- 1393
+ID + + I FL++ + +++ +LK ++ + +LKD+
Sbjct: 909 FIDQEIENEIQFLNNINQQQKQEVDNQNDQQVFAQDIPTSLKEQLQKEIQQLKDQSILEL 968
Query: 1394 ----------------EEERGKISENLERIS-KLQKMNNELAERSKSQNSIXXXXXXXXX 1522
EEE I + ERI KLQ EL + + N I
Sbjct: 969 QQYNEEVIQQLKNILNEEELDNIDDGFERIQIKLQHARQELDQ--EQANKIIELEKKLLI 1026
Query: 1523 XXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQK 1702
+ +L++L + N NS + + T+S+
Sbjct: 1027 KQDETGRLESQI------KELQQLVKKQNKQNSSPKIQNQQQDSRNYTVSAA-------- 1072
Query: 1703 FEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNI 1882
E E+ QK++ S ++ I+KL E+ A N I K DN + +
Sbjct: 1073 VETEEDQKLINSLQNQIQKLKQ----EIQKANTDFN------IIKDDNKSFVSQIEILKK 1122
Query: 1883 QNQVAVSQEQHIEHQCKEELEGHIADLVLNDFS--NDILSWSRRKEEAVVHDDEFDAERI 2056
QNQ+ +Q Q+++ + LE I L + S + S S+ ++ + + + +
Sbjct: 1123 QNQLLETQNQNVQKNI-QTLEQTIKTLNEQNKSLQKEKESISKNLQQKTQNLAKSEDQVA 1181
Query: 2057 ALLNELKSLHQDLELLKA------EEAVKSLSNNVGVS--TKGIHYFSQLIQEGKDGEAS 2212
NE K + +L+ E KS + + G S +KG + +Q Q+
Sbjct: 1182 QFKNENKLYQEKCGILEKRIKELEETKKKSSTPSAGTSPNSKGKNQNTQQQQQQLQQYIK 1241
Query: 2213 DVQGKSRALRRHSTGQAFREPPKP------EDLYTTYSEGKIVEPHPTEEKKLLAILAFE 2374
D + + L + +E K EDL + E + EE + +
Sbjct: 1242 DCEQLKQLLIEYEQKFLEKEEDKSKLLAEIEDLKSKLEEAVTIIKQQEEENGKIK----Q 1297
Query: 2375 TADASDSPLRNWPKEQL---------LGHFKQSFAGLKRE----YELELQRKTEEIYDLK 2515
S S L+ KE++ L K+ A +++ Y+ L K +EI +L
Sbjct: 1298 NNQNSTSFLKEKLKEEIEQNLKRVKDLEKEKEDIANEQQDKIELYQNSLSEKQQEIDELI 1357
Query: 2516 RLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKV-LQENKLLPVEEVQRYKMLCVLKEE 2692
N N L + EI EKV L + K + + Q+ K++ ++K +
Sbjct: 1358 SKN-NNLNELIDQYQREIKKCKEKMEEIKKMQEKVNLDQQKNMQDQLAQKNKLIEMMKND 1416
Query: 2693 L---QSKIDSLLKEIKE-KDSNSKVLAEKLSDALKKSA--DHAQRESHLLKHIADLEAGI 2854
+ +I+ L +EI+E K ++ LS + ++S + Q+E K I I
Sbjct: 1417 SLDDKEEIELLKQEIEELKQQLQATQSKPLSSSRQESQYKEFQQKEEEFKKLIKQQNEKI 1476
Query: 2855 TDREIMTSVCSDVLTAL-FVEMVREKEFSLSLATKEQETVNQKQ-MSLRKMLEDKDKLLC 3028
E D L + F E + + L A +KQ S+ +++ D+D
Sbjct: 1477 AKME------QDCLQKMEFEEEIARLQQELQSALDSHNDSGKKQNQSIDQIINDQD---- 1526
Query: 3029 LVGEENKEHKRQIA--ILEKLKE-ETENNPGRVFLQSEEREKIEEQ-KRVLDQALQECEE 3196
+ G +NK +++ + E++KE E ENN R ER+ +++Q + ++D+ +E ++
Sbjct: 1527 IDGLQNKRNQQNSFEDLQERVKELEEENNDLREI--QNERDCLQQQIQEIIDKNKEETDQ 1584
Query: 3197 LKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLE 3376
L++ ++ I + + EK+ + L+ ++ D ++E
Sbjct: 1585 LQSTVRLLTQQIQKNQIDSEKIIQNLQ---NEIGSMTQFIKQQEQLIQQQNAEHDQKEIE 1641
Query: 3377 LRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAME-------QKEAVLVEKLFE 3535
R +E N I + I+ + + +E N +L Q+ +E Q+ + +++
Sbjct: 1642 FRQIIKEKDNYIFTQRDQIEQITDQIKEKNNQLIQMQENIEELKQNYEQQLQINNDQISN 1701
Query: 3536 GEQKILLLESSQSATREQTEKYRDL-LNSLTEEHADLKKQFLSATEELQ----------- 3679
Q + + RE+ EKY++ L+ L + +L + EELQ
Sbjct: 1702 SNQNFQIQIENLQKLREEEEKYQNSNLSDLNNQIQELNQALSQKEEELQEINMKQSVIQQ 1761
Query: 3680 ---SKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQYQT 3823
+K ++LE + KE+L + L E+ L++ E + E+Q ++
Sbjct: 1762 SYENKIKELEQNCLQIFEQKEELQIRISQLDEEIADLKSVEKKSFEEQTES 1812
>ref|XP_005159741.1| PREDICTED: titin isoform X4 [Danio rerio]
Length = 15580
Score = 136 bits (343), Expect = 6e-29
Identities = 241/1198 (20%), Positives = 484/1198 (40%), Gaps = 108/1198 (9%)
Frame = +2
Query: 539 EEEFKEALAAKD---SENFLLNKKIEDLNHKIWSLE---ETLQYKEEVILSSHETISERD 700
E + KE L K+ S+ LL K +E+L K+ +E E+L+ E++ + E + +
Sbjct: 3628 EIQMKEVLTEKELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMK 3687
Query: 701 RLLKDFIHEKDLM----QQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNT 868
L+ E + + Q Q E+ A + ++ DNI +H + Q
Sbjct: 3688 TDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMK 3747
Query: 869 QSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDE 1048
Q D + + E QN+++E+EK+ + I + EL + L + D I+++K+E
Sbjct: 3748 QKQDELDQLKTEIQNLQQELEKE--KEIIMKDRSELDLKQSELDKQQTNMNDIIETMKNE 3805
Query: 1049 CHAKEMSKQA------EISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRND 1210
+ K+ EI K H ++ NS E L ++ + F E +++ Q++ +
Sbjct: 3806 RKQLDKDKEEMEEQKREIEKEKHDFDQG-RNSLDEDLKMMKLQKQVFEEEKNKLEQMKIE 3864
Query: 1211 MYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDE 1390
L E +++ K+K+E
Sbjct: 3865 -----------------LEREAGEIR-----------------------------KIKEE 3878
Query: 1391 LEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMA 1570
++ ER + + E + + ++ LAE +K + I
Sbjct: 3879 IQNERQSLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEK------ 3932
Query: 1571 FGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESH 1750
S EE+ + I+ + K+ + D + LQ + Q+ EIEK + ++S +
Sbjct: 3933 --SNFEEMRENISKQTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAA 3990
Query: 1751 IEKLVNDSLHEVDSAFCSLNSRFYSL---IHKVDNSGETLRAFVKNIQNQV----AVSQE 1909
I K+V D H++ SL+ SL +N E L+ ++ + + E
Sbjct: 3991 IIKIVEDLQHKI----ISLDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLE 4046
Query: 1910 QHIEHQCKEELEGHIA----------------DLVLNDFSNDILS--WSRRKEEAVVHDD 2035
+ Q EE+ I D+VLN+ + DI S + ++ ++ +
Sbjct: 4047 TQHDRQRVEEMTAQITKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKE 4106
Query: 2036 EFDAERIALLNELKSLHQDL---------ELLKAEEAVKSLSNNVGVSTKGIHYFSQLI- 2185
+ + E+ +EL + +DL E+ K E ++ ++ N+ + I + + +
Sbjct: 4107 KHNLEKTR--SELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQMK 4164
Query: 2186 --QEGKDGEASDVQGKSRALRRHS-------------TGQAFREPPKPEDLYTTY-SEGK 2317
Q+ D +++Q + L + + ++ D+ T +E K
Sbjct: 4165 QKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNERK 4224
Query: 2318 IVEPHPTEEKKLLAILAFETADASDSPLRNWPKE-QLLGHFKQSFAGLKREYE---LELQ 2485
+++ E ++ + E D D +++ ++ +++ KQ K + E ELQ
Sbjct: 4225 LLDKDKEEMEEQKQEMEKE-RDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQ 4283
Query: 2486 RKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXV--AEITGKFEKVLQENKLL---PVE 2650
R+ +EI +K NE+ L V AE T + +++L E ++ +
Sbjct: 4284 READEIRKIKEETQNERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMA 4343
Query: 2651 EVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKH 2830
++QR K + EE++ I ++I+ + SK+ ++L L+ Q E + K
Sbjct: 4344 DLQREKRIL---EEMRENISKQTEDIENEKEKSKLREDELK-KLQTEVQKQQSEIDMEKT 4399
Query: 2831 IADLEAGITDRE---IMTSV--CSDVLTALFVEMVREKEF---SLSLATKEQETVNQKQM 2986
+ E + RE +MT + S+ + E++ EKE +L K+ E + QK M
Sbjct: 4400 NIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLM 4459
Query: 2987 SLRKMLEDKDKLLCLVGEEN---KEHKRQIAI----LEKLKEETENNPGRVFLQSEEREK 3145
S+ + E G E K+ K + I +EK+K ET+++ RV E+ +
Sbjct: 4460 SIERDSESLKLDREAFGNEKEVLKQMKTDLQIQADEIEKIKLETQHDRQRV---EEKTAQ 4516
Query: 3146 IEEQKRVLDQALQE-------CEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXX 3304
I++ + ++ + E E+ DI+ K I S++ +++ L K+
Sbjct: 4517 IQKDRDEINNLIVETNRKDMVLNEMDRDIEEK---IKSIQSDKDMLEKE----------- 4562
Query: 3305 XXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYT 3484
NL+ + EL E L+ + E + DI+ + K + +
Sbjct: 4563 --------------RHNLEKTRSELARAKENLETQREIERKDIEKMKKNISREMHEIKHQ 4608
Query: 3485 QKAMEQKEAVL---------VEKLFEGEQKILLLESSQSATRE-QTEKYRDLLNSLTEEH 3634
++ M+QK+ L +++ E E++I++ SQ R+ + +K + +N + E
Sbjct: 4609 EEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETM 4668
Query: 3635 ADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSE 3808
+ +KQ EE + +++++E + ++ L DE+LK LQ + E S+
Sbjct: 4669 KNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSL---DEDLKMMKLQKQVIEEEKSK 4723
Score = 124 bits (310), Expect = 4e-25
Identities = 247/1298 (19%), Positives = 522/1298 (40%), Gaps = 115/1298 (8%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNT 451
IE E L+ K K A+ + +++ + L+ M +L ++ L ED +
Sbjct: 4977 IEEEKNKLEQMKIELEKEADEIRKIKEETQNERQRLEKMTEELKKEKESFTHLAEDTKTE 5036
Query: 452 KDLLDTV-------------------ESGLYVSNVVSDAV---------------LNGVV 529
K +LD + E +S D+ L +
Sbjct: 5037 KKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQLQAEI 5096
Query: 530 SAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLE---ETLQYKEEVILSSHETISERD 700
Q+ E K + +SE + K ++DL HK++SL+ E+L+ E + E + +
Sbjct: 5097 HKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREVLKQIK 5156
Query: 701 RLLKDFIHEKDLMQQRAQETEQKLAS--------RD--NEMMHMVLEKDNIILSLHKQIE 850
LK E + ++ Q Q++ RD N ++ KD ++ + +I+
Sbjct: 5157 TDLKRKAEEIEKIKLETQHDRQRVEEMTAQIQKERDKINNLIEETNRKDMVLNEIKTEIK 5216
Query: 851 LQSQNTQSLDCFRRDEIEDQN------------IKEEIEKQIVETIYVTQIQELGEE--- 985
+ + +S RD +E + KE +EKQ I + +IQ+ E+
Sbjct: 5217 EKIKAIES----DRDMLEKEKHDLEKTRSKLLRAKENLEKQ--RKIKLAEIQKEREDLEK 5270
Query: 986 ---------HDLLRLESA--KYQDEIQSLKDECH--AKEMSKQAEISKLSHTLEESIMNS 1126
HD+ E + QDE+ LK E +E+ K+ EI + + + S
Sbjct: 5271 MNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRS-QLDLRQS 5329
Query: 1127 NLESLFT-----AEIYENTFRELG---DQISQLRNDMYSKNSYIDSLASRIDFLSSECNK 1282
L+ T E +N ++L ++ + + +M + D +D + K
Sbjct: 5330 ELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDE-DLKMMK 5388
Query: 1283 LQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISK-LQKMNN 1459
LQ+Q +A ++ K+K+E++ ER +NLE++++ L++
Sbjct: 5389 LQKQVLEDEKSKLEQMKIELEREA---VEIRKIKEEIQNER----QNLEKMTEALKEERE 5441
Query: 1460 ELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKE 1639
+LAE +K N + S LEE+ + I+ ++ K+
Sbjct: 5442 DLAEETKKNNQVLDEMKVANESTLADILREK--------SNLEEMRENISKQTEDVENKK 5493
Query: 1640 AEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEV-----DSAFCS 1804
+ D + LQ + Q+ EIEK + ++S + I K V D H++ D+
Sbjct: 5494 ENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLK 5553
Query: 1805 LNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFS- 1981
L+ + +N E L+ ++ + ++ +E Q + +A + D
Sbjct: 5554 LDREAF------ENEKEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDE 5607
Query: 1982 -NDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTK 2158
N+++ + RK+ V+++ D E ++KS+ D ++L+ E+ +++ +
Sbjct: 5608 INNLIEETNRKD-MVLNEKNRDIEE-----KIKSIQSDKDMLEKEK------HDLEKTRS 5655
Query: 2159 GIHYFSQLIQEGKDGEASDVQGKSRALRRHSTG----------QAFREPPKPEDLYTTYS 2308
++ + +++ K+ +++Q + L + + Q + K ++L +
Sbjct: 5656 ELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKT 5715
Query: 2309 EGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQR 2488
E + ++ +EK+++ D S LR ++ + +K E + +L +
Sbjct: 5716 EIQNLQQELEKEKEIIM------KDRSQLDLRQSELDKQQTNMNDIMETMKNERK-QLDK 5768
Query: 2489 KTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYK 2668
EE+ + K+ + E++ + + + +K ++ K + EE + +
Sbjct: 5769 DKEEMEEQKQEMEKERDNMDQSR------------KSLDEDQKKMKLQKQMFEEEKNKLE 5816
Query: 2669 MLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDAL---KKSADHAQRESHLLKHIAD 2839
+ K EL+ + D + K IKE+ N + EK+++ L K+S H ++ K I D
Sbjct: 5817 QM---KIELEREADEISK-IKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILD 5872
Query: 2840 LEAGITDREIMTSVCSD--VLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDK 3013
E + + M + + +L + + + KE+ E+E ++ L+K+ +
Sbjct: 5873 -EMKVANESSMADLQREKSILEEMRENISKLKEY----IDNEKEKSKLREDELKKLQTEV 5927
Query: 3014 DKLLCLVGEE--NKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQE 3187
K + E N E +R I EK + +E ++K E+ + + + L E
Sbjct: 5928 QKQQSKIDMEKTNIESERAAMIREKQN-----------MMTELKKKSEDVEIQMKEILTE 5976
Query: 3188 CEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSM 3367
E L ND + D+++L+++ L + + + + D +
Sbjct: 5977 KELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEI 6036
Query: 3368 QLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQK 3547
+ +++ + + +E+ + I KE++++N + T + K+ VL EK + E+K
Sbjct: 6037 E-KIKLETQHDRQRVEEMAAQIQ---KERDKINNLIEETNR----KDMVLNEKNRDIEEK 6088
Query: 3548 ILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEV-------A 3706
I ++S + ++ + L + DL+KQ + E+Q + D+E
Sbjct: 6089 IKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENITRE 6148
Query: 3707 MTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQYQ 3820
M E K +E++ N K+ +L EI N +++ +
Sbjct: 6149 MHEIKHQEEQM-----NQKQDELDQLKTEIQNLQQELE 6181
Score = 114 bits (285), Expect = 3e-22
Identities = 238/1256 (18%), Positives = 500/1256 (39%), Gaps = 82/1256 (6%)
Frame = +2
Query: 287 GGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLD 466
GGL T + LE+M+ + ++M L ++ + L +DI K+ D
Sbjct: 8698 GGLKTEIENTKRDKSNLEKMKAELEEKQQEEESMREILQKEKEELEQLKKDINREKE--D 8755
Query: 467 TVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETL 646
S V + + + + G Q+ +KE L E + +E LN + L +TL
Sbjct: 8756 IEISRELVESEIYEGEVKGFTDVQK--YKEELQIVTEELLTKKRNLEQLNSDVQHLMQTL 8813
Query: 647 QYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQK-LASRDNEMMHMVLEKDNI 823
EEV + + +E + + + + +++++ ++ E+ + EMM + LE N+
Sbjct: 8814 ---EEVDIQYIKKKAELEHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINM 8870
Query: 824 -ILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLR 1000
IL + +E + +N RR++ E + + E+++Q E + Q L E D +
Sbjct: 8871 EILQKREDMEKEKEN------LRREKQETELFRGELQRQRDEV--ESSRQALIMEKDQFK 8922
Query: 1001 LESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFREL 1180
L+ ++E+ + ++ H + + + ++ L ES+ N ++
Sbjct: 8923 LKIDHQRNEMSAAFEKEHKRLENMENDLENQRAKLAESL---------------NDAAKM 8967
Query: 1181 GDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASM 1360
++ Q++N++ + ++ + + +E K++++ L+
Sbjct: 8968 EQKLQQMKNELNKEKEQVEEMKQMV---KTERVKIEQEKEEMRKQTQEIEDGHEKLQKKT 9024
Query: 1361 EMQCSKLKD-ELEEERGK-ISENLE-RISKLQKMNNELAERSKSQNSIXXXXXXXXXXXX 1531
E+ L+D E +R K +S L+ + ++K N E+ + +S + +
Sbjct: 9025 EIADKLLQDANSESDRLKDLSMKLQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLK 9084
Query: 1532 XXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEI 1711
+ + E + + ++ ++ ++E + K +I
Sbjct: 9085 NDRDAYEKDMTHLELKREELVRETEDLERKILQQREQDEMA---------------KRDI 9129
Query: 1712 EKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQ 1891
E + L+ + I K N+ E+++ +S K+ L++ ++N+
Sbjct: 9130 ENQTEALEVMKVDILKKRNEFAKEMENV--------HSERQKLLLLQGALQSQESELENR 9181
Query: 1892 VAVSQEQHIEH------QCKEELEGHIADLVL---NDFSNDILSWSRRKEEAVVHDDEFD 2044
V + +++H++ +C+++L +++ V N++ I R KE+ + ++ +
Sbjct: 9182 VFMEEQKHLKQAKAETEECRKQL-AEMSETVTTEQNEYRKLIEELQREKEQLEISKNQIE 9240
Query: 2045 AERIALLNELKSLHQDLELLKAEEA----VKSLSNNVGVSTKGIHYFSQLIQEGKDGEAS 2212
E+ L N +L + LE L+ E+A K+ + +K I + +E +
Sbjct: 9241 QEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWV 9300
Query: 2213 DVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAIL--AFETADA 2386
+++G+ + + E + +E H E KK+ + L + E ++
Sbjct: 9301 EIEGEKKRMEE---------------------ETRRLEMHREEIKKVDSELQKSRENIES 9339
Query: 2387 SDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDL---KRLLLNEKNGLHAXX 2557
+ + N +E L K K E E E QR + DL K + +++
Sbjct: 9340 REEKINNKMEELL--QMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDII 9397
Query: 2558 XXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKM-LCVLKEELQSKIDSLLKEIKE 2734
+ K K L E L V++++ + K+E++ L KE +E
Sbjct: 9398 DIKIQEKEREIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQE 9457
Query: 2735 KDSNSKVLAEKLSD----------------ALKKSADHAQRESHLLKHIADLE-AGITDR 2863
K L +++ D ALK + ++E+ ++K LE + I +
Sbjct: 9458 LKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEM 9517
Query: 2864 EIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQM---SLRKMLEDKDKLLCLV 3034
++ + E +EKE SL + ET QKQM S KM+E+K+++ L
Sbjct: 9518 QLKIFKQQRLNDQTREENKKEKE---SLEQQRFETEQQKQMLEISTTKMMEEKNEMADLS 9574
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVF-LQSE---EREKIEEQKRVLDQALQECEELK 3202
E K LEK+ +T V +Q+E + + IE+Q +++ EE +
Sbjct: 9575 RELQKAKDE----LEKIAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEKE 9630
Query: 3203 NDIQNKHSDI--------------DSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXX 3340
IQ K +I +++ EE K L M
Sbjct: 9631 LSIQRKEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQKNNKDFELLE 9690
Query: 3341 XISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEA--- 3511
I S L++ + +L+ + E+ K+ +E + +++ KEKE L + Q EQ E
Sbjct: 9691 KIRSELENEKYDLQIWTEQQKHLVEVQLQELE---KEKERLEKMEIELQSKREQTEKEKA 9747
Query: 3512 --------------VLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLK- 3646
V+ +K + + LE+ ++ +E+ EK + L EE ++
Sbjct: 9748 DLNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQI 9807
Query: 3647 --KQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSE 3808
+ EE++ ++ LE++ + K +KE+ + E + K + +I N+E
Sbjct: 9808 EAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEE-QIQNNE 9862
Score = 114 bits (284), Expect = 4e-22
Identities = 214/1216 (17%), Positives = 493/1216 (40%), Gaps = 33/1216 (2%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNT 451
+E E L+ +S K+ E LE+ + +T ++ DL + N + + +I++
Sbjct: 4103 LEKEKHNLEKTRSELYKVKEDLEKQK---ENTLAEIQKEREDLEKMNENITIEMHEIKHQ 4159
Query: 452 KDLLDTVESGLYVSNVVSDAVLNGVVSAQEE--EFKEALAAKDSENFLLNKKIEDLNHKI 625
++ + + L D + + + Q+E + KE + SE L +++ +
Sbjct: 4160 EEQMKQKQDEL-------DQLKTEIQNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNM 4212
Query: 626 WSLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMV 805
+ ET++ + +++ E + E +K M++ +Q + S D ++ M
Sbjct: 4213 NDIIETMKNERKLLDKDKEEMEE----------QKQEMEKERDNMDQSIKSLDEDLKMMK 4262
Query: 806 LEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEE 985
L+K I +K +++ + + D R+ + E QN ++ +EK I E
Sbjct: 4263 LQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQNERQSLEKMTKALIK--------ER 4314
Query: 986 HDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESL-FTAEIYE 1162
DL+ L A+Y + + DE S A++ + LEE N + ++ E +
Sbjct: 4315 EDLVHL--AEYTKREKEMLDEMQVANKSSMADLQREKRILEEMRENISKQTEDIENEKEK 4372
Query: 1163 NTFRELGDQISQLRNDMYSKNSYIDSLASRID----FLSSECNKLQEQXXXXXXXXXXXX 1330
+ RE D++ +L+ ++ + S ID + I+ + E + +
Sbjct: 4373 SKLRE--DELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQNMMTELKKKSEDVEIQM 4430
Query: 1331 XXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXX 1510
T K +E + LK ++E+ + K+ ++ER S+ K++ E
Sbjct: 4431 KEILTEKELLENDSNLLKKDMEDLKQKLM-SIERDSESLKLDRE---------------- 4473
Query: 1511 XXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVL 1690
AFG++ E V+ + + ++ D I ++
Sbjct: 4474 -------------------AFGNEKE-----------VLKQMKTDLQIQADEIEKIKLET 4503
Query: 1691 SNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAF 1870
+ + +E+ +Q I L+ ++ + D ++ I + + + L
Sbjct: 4504 QHDRQRVEEKTAQIQKDRDEINNLIVET-NRKDMVLNEMDRDIEEKIKSIQSDKDMLEKE 4562
Query: 1871 VKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAE 2050
N++ + + + E+E + + + S ++ ++E+ DE D
Sbjct: 4563 RHNLEKTRSELARAKENLETQREIERKDIEKMKKNISREMHEIKHQEEQMKQKQDELDQ- 4621
Query: 2051 RIALLNELKSLHQDLE-----LLKAEEAVKSLSNNVGVSTKGIHYFSQLI-----QEGKD 2200
L E+++L Q+LE ++KA + + + ++ + + Q KD
Sbjct: 4622 ---LKTEIQNLQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKD 4678
Query: 2201 GEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETA 2380
E ++ Q + +H Q+ + EDL + +++E ++ K++ L E
Sbjct: 4679 KEETEEQKQEMEKEKHDFDQSRKS--LDEDLKMMKLQKQVIEEEKSKLKQMKIELEREAD 4736
Query: 2381 DASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRL-------LLNEKN 2539
+ + Q+ ++ + + + +RK + + ++K +L E++
Sbjct: 4737 EIRKVKEETQNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRERS 4796
Query: 2540 GLHAXXXXXXXXXXXXVAEITGKFEKV-LQENKL--LPVEEVQRYKMLCVLKEELQSKID 2710
L ++ K EK+ L+E KL L E ++ K ++ +
Sbjct: 4797 NLQEMRENISKQ----TEDVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNIERERA 4852
Query: 2711 SLLKEIKEKDSNSKVLA-EKLSDALKKSADHAQRESHLLKHI-ADLEAGITDREIMTSVC 2884
+++K+++ D SK+++ ++ +++LK + + E LK + +LE RE
Sbjct: 4853 AIIKDVE--DLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELE-----RE------ 4899
Query: 2885 SDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQ 3064
+D + + +E E++ + ET+N ++ L K E+ E+ +E +++
Sbjct: 4900 ADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQ-------EQKQEMEKE 4952
Query: 3065 IAILEKLKEETENNPGRVFLQS----EEREKIEEQKRVLDQALQECEELKNDIQNKHSDI 3232
+++ ++ + N + LQ EE+ K+E+ K L++ E ++K + QN+ +
Sbjct: 4953 RHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEADEIRKIKEETQNERQRL 5012
Query: 3233 DSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEI 3412
+ + EE +K + + + ++L + L EE++ I
Sbjct: 5013 EKMTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNL----EEMRENI 5068
Query: 3413 EKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQT 3592
K++ D + KEKE++ R + +EQ +A + ++ +GE K +E S + +
Sbjct: 5069 SKQTEDSE---KEKEKIRLR----EDELEQLQAEIHKQ--QGEIK---MEKSNNESERA- 5115
Query: 3593 EKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKD 3772
++ ++ DL+ + S +L+S + D E E + LK+ + +D K ++
Sbjct: 5116 --------AIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREVLKQ--IKTDLKRKAEE 5165
Query: 3773 LQLRAFEIANSEKQYQ 3820
++ E + ++ +
Sbjct: 5166 IEKIKLETQHDRQRVE 5181
Score = 113 bits (283), Expect = 6e-22
Identities = 235/1290 (18%), Positives = 522/1290 (40%), Gaps = 108/1290 (8%)
Frame = +2
Query: 275 EVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTK 454
E ED +T+K+ + L+ M++ T + +L + + ED+ N K
Sbjct: 5439 EREDLAEETKKN-----NQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKK 5493
Query: 455 DLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSL 634
+ L E L L + Q+ E ++ +SE + K +EDL HKI L
Sbjct: 5494 ENLRLREDEL--------RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICL 5545
Query: 635 E---ETLQYKEEVILSSHETISERDRLLK---DFIHEKDLMQQRAQETEQKLAS---RDN 787
+ E+L+ E + E + + L+ D I + L Q ++ +++A+ +D
Sbjct: 5546 DRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDR 5605
Query: 788 EMMHMVLE----KDNIILSLHKQIELQSQNTQSLDCFRRDEIED--------QNIKEEIE 931
+ ++ ++E KD ++ ++ IE + ++ QS E D +KE++E
Sbjct: 5606 DEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLE 5665
Query: 932 KQIVETIYVTQ-----IQELGEE-----HDLLRLESA--KYQDEIQSLKDECH--AKEMS 1069
KQ T+ Q ++++ E H++ E + QDE+ LK E +E+
Sbjct: 5666 KQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELE 5725
Query: 1070 KQAEISKLSHTLEESIMNSNLESLFTA--EIYENTFRELGDQISQLRNDMYSKNSYIDSL 1243
K+ EI + + + S L+ T +I E T + Q+ + + +M + ++
Sbjct: 5726 KEKEIIMKDRS-QLDLRQSELDKQQTNMNDIME-TMKNERKQLDKDKEEMEEQKQEMEKE 5783
Query: 1244 ASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQC---SKLKDELEEERGKI 1414
+D ++ Q++ +K +E + SK+K+E + +R ++
Sbjct: 5784 RDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRL 5843
Query: 1415 SENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEEL 1594
+ E + + ++ LAE +K++ I + LEE+
Sbjct: 5844 EKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSI--------LEEM 5895
Query: 1595 TDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDS 1774
+ I+ ID ++ + D + LQT + Q+ +I+ + ++S + + + +
Sbjct: 5896 RENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNM 5955
Query: 1775 LHEVDSAFCSLNSRFYSLIHKVD---NSGETLRAFVKNIQNQV---------------AV 1900
+ E+ + + ++ + + N + L V+N+Q ++ A
Sbjct: 5956 MTELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAF 6015
Query: 1901 SQEQHIEHQCKEELE---GHIADLVLN-------------------DFSNDILSWSRRKE 2014
E+ Q K +L+ I + L D N+++ + RK+
Sbjct: 6016 ENEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKD 6075
Query: 2015 EAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEG 2194
V+++ D E ++KS+ D ++L+ E +N+ + ++ + +++
Sbjct: 6076 -MVLNEKNRDIEE-----KIKSIQSDKDMLEKER------HNLEKTRSELYKVKEDLEKQ 6123
Query: 2195 KDGEASDVQGKSRALRRHSTG----------QAFREPPKPEDLYTTYSEGKIVEPHPTEE 2344
K+ +++Q + + + + Q + K ++L +E + ++ +E
Sbjct: 6124 KENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKE 6183
Query: 2345 KKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLL 2524
K+++ D S LR ++ + +K E + +L + EE+ + K+ +
Sbjct: 6184 KEIIM------KDRSQFDLRQSELDKQQTNMNDIMETMKNERK-QLDKDKEEMEEQKQEM 6236
Query: 2525 LNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSK 2704
EK+ + K K+++ K + EE + + + K EL+ +
Sbjct: 6237 EKEKHDFDQSR------------KSLDKDLKMMKLQKQVFEEEKNKLEQM---KIELERE 6281
Query: 2705 IDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVC 2884
D + K IKE+ N + EK+++ LKK E H+A E ++EI+ V
Sbjct: 6282 ADEIRK-IKEETQNERQSLEKMTEELKK-------EKESFTHLA--EDTKKEQEILDKV- 6330
Query: 2885 SDVLTALFVEMVREK---EFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEH 3055
+L ++ +EK E +K+ E V K+ +LR ++ +L + ++ +E
Sbjct: 6331 KVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQQREI 6390
Query: 3056 KRQIAILEKLK----EETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKH 3223
+++ +E + + E+ ++ + E ++ + + + +++K +++ +
Sbjct: 6391 EKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELEREA 6450
Query: 3224 SDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYN-EEL 3400
+I+ ++ E + +++ M + N + QL+ EE
Sbjct: 6451 DEIEKIKLETQHERQRVEEMTADFME---------------TMNNERKQLDKNKVMIEEQ 6495
Query: 3401 KNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSAT 3580
K E+EKK D+D K +E + + ++ +E+++ L + E++ + + T
Sbjct: 6496 KQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLEREADEISKIKEET 6555
Query: 3581 REQTEKYRDLLNSLTEEHADLKKQFLSATEELQ----SKERDLEVAMTETKFLKE----- 3733
+ + + + N+L EE L ++ + L + E L E + L+E
Sbjct: 6556 QNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLADLQKEKRILEEMRENI 6615
Query: 3734 -KLLVSDENLKEKDLQLRAFEIANSEKQYQ 3820
K + EN KEK +LR E+ + + Q
Sbjct: 6616 SKQIEDIENEKEKS-KLREDELKKLQTEVQ 6644
Score = 111 bits (277), Expect = 3e-21
Identities = 233/1162 (20%), Positives = 476/1162 (40%), Gaps = 76/1162 (6%)
Frame = +2
Query: 524 VVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDR 703
+V+ +EE K+ ++S N + KK +L H+ L + Q E++I S + + +R
Sbjct: 13182 LVNMEEEIKKQRRVLEESMNEMTKKK-SELQHERSELYKQKQQLEDMIASESKRDVDTER 13240
Query: 704 LLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDC 883
+D E+ L ++R + + K +L++ + + ++I + ++ + +
Sbjct: 13241 SRQDKEDEQILKREREEIADMK---------DQLLKEKEDVETTKERINREKEHIEKMQS 13291
Query: 884 FRRDEIEDQNIKEE------IEKQIVETIYVTQIQELGEEHD---LLRLESAKYQDEIQS 1036
D+ E+ +++ + E Q+ +Q+L +E + L ++ K +++
Sbjct: 13292 QLNDQKEEMDLENQKLLYMKTEIQVKTNALEKMMQDLQKERENVNALVIQHQKEREQRDI 13351
Query: 1037 LKDECHAKEMSKQAEISKLSHTLE----------ESIMNSNLESLFTAEIYENTFRELGD 1186
L +E KE +AEI + +E I N E +E EN ++
Sbjct: 13352 LIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTRSEELENLIKKQQK 13411
Query: 1187 QISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEM 1366
+ N+M + ++ + + ++ S+E E+ LK +E
Sbjct: 13412 EFETKENEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILER 13471
Query: 1367 QCSKLKDELEEERGKISENLERISKLQK-MNNELAERSKSQNSIXXXXXXXXXXXXXXXX 1543
+ K EL +E+ ++ + + ++K M +E+ +N +
Sbjct: 13472 E----KSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELE--------------- 13512
Query: 1544 XXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQ 1723
+ + + ++++ IDK + E+ ++I + L K E E +
Sbjct: 13513 -----------DEKKSMLSRLSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKR 13561
Query: 1724 KVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVS 1903
L ++ IEK+ D L + SL L K + E +R K +Q +S
Sbjct: 13562 TQL---DNTIEKMNMDKL-SIQREKDSLEEIKADLQRKAEKLDEEMR---KAVQITSQIS 13614
Query: 1904 QEQHI---EHQCKEELEGHIADL-----------VLNDFSNDILSWSRRKEEAVVHDDEF 2041
Q+ I + + +EEL AD+ L +IL S+ + + + D E
Sbjct: 13615 QDAKILDDDREKEEELRSMRADIERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEK 13674
Query: 2042 DAERIAL-LNELKSLHQDLE-----LLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDG 2203
+R L L EL+ LE + K ++AV SL N V + + + E +
Sbjct: 13675 QRKRNDLTLQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRK- 13733
Query: 2204 EASDVQGKSRALRRHSTGQAFREPPKPEDLYTT-----YSEGKIVEPHPTEEKKLLA--I 2362
E D++ +R++ST + +E D++ ++ + ++ EE++ L I
Sbjct: 13734 EMDDLR-MQLEMRQNSTNKQQQE----VDVFIVENMKMRNDLESMKTLLDEERRQLQDNI 13788
Query: 2363 LAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNG 2542
FE P + +Q ++ +K E E ++++ EEI L + ++ K
Sbjct: 13789 KTFEDQKNVLHPSKTDAVQQ-TDELEKFTTDIKTEKE-HVEKEREEIDVLNKEIIKSKEE 13846
Query: 2543 LHAXXXXXXXXXXXXVAEITGKFEKV-----LQENKLLPVEE----VQRYKMLCVLKEEL 2695
L + EI GK ++ L+ + L ++ VQ K + + E
Sbjct: 13847 LQSLNLEIEMFK----QEIAGKRAQIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEK 13902
Query: 2696 QSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLL-KHIADLEAGITDREIM 2872
+++++ + K+K+ E+L + ++ + +L K ++E +IM
Sbjct: 13903 KTEVELQMNLQKQKNE-----LEELRNTIEAEKHQVENRKIMLDKQQKEVE------DIM 13951
Query: 2873 TSVCS--DVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLE----DKDKLLCLV 3034
T + S DVL +EK L+ E V ++Q L ++LE D + ++
Sbjct: 13952 TVIKSERDVLE-------KEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKII 14004
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLD----QALQECEELK 3202
E + +R+ A L++LKEE E R LQ +++ I+++K L+ + +E LK
Sbjct: 14005 ESEKQSIERERAELKRLKEEVEVQHERTLLQ-QDKNMIQKEKEHLEGEKARTTEEIHNLK 14063
Query: 3203 NDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLE-- 3376
+I+ K S++D L +E E ++ + + +++E
Sbjct: 14064 EEIKRKSSELDMLNKEIEAKRQE----------------------EELHGLPEEIEIEDH 14101
Query: 3377 LRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQ-------KAMEQKEAVLVEKLFE 3535
L+ ++ L+ EI KK D K + + R A TQ K E+++ L E +
Sbjct: 14102 LKKEDDVLREEIIKKQ-QTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRALEETVAT 14160
Query: 3536 GEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTE 3715
++ ++++ + T E ++ RD LN+ +E A +K ++L+ + D++ M E
Sbjct: 14161 TAKQPIVIKLEDTLTSE-VQEMRDHLNNEIKELARMKTIMKMEKDQLKQAKSDIQTQMEE 14219
Query: 3716 TKFLKEKLLVSDENLKEKDLQL 3781
+ E+ + +EK LQL
Sbjct: 14220 FERNMEEAMEEKSRNEEKLLQL 14241
Score = 108 bits (270), Expect = 2e-20
Identities = 257/1319 (19%), Positives = 522/1319 (39%), Gaps = 140/1319 (10%)
Frame = +2
Query: 230 VMDGQGCDISVTSFIEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNF----- 394
+ D Q I S ++ E+ + + K ETL+ ME H +K+++
Sbjct: 10693 IADEQDLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRL 10752
Query: 395 --DLGQDNPGVPGLLEDIRNTKDLLDTVESGL-----YVSNVVSDAVLNGVVSAQ-EEEF 550
DL + + V +D+ N +DLL+ + + + + + VS Q E++
Sbjct: 10753 KEDLEKMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQQRIDE--FDAQVSKQKEQDL 10810
Query: 551 KEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEK 730
+ K+ L K + K + E ++ ++E E E R++ + K
Sbjct: 10811 PKEKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVE-TERK 10869
Query: 731 DLMQQRAQ--------ETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCF 886
+L Q +++ + EQK + N+ M M+ ++ + + +I Q Q +
Sbjct: 10870 ELYQIKSELERVRSEIDHEQK---KLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSE 10926
Query: 887 RRDEIEDQNI-KEEIEK--QIVETIYVT-----------------QIQELGEEHDLLRLE 1006
++I+ N+ K +IEK +IVE + V + Q++ +E +LL
Sbjct: 10927 LDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQN 10986
Query: 1007 SAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGD 1186
AK Q+E + +K EI K TL E ++ E I E T R D
Sbjct: 10987 KAKLQNENERIK--------KVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKED 11038
Query: 1187 QISQLRNDMYSKNSYI----DSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKA 1354
+ ++ D+ + ++ D L + ++ E +LQ++ A
Sbjct: 11039 -LEKMSTDINEQKLHLKNQRDLLEQEREEINHEMTQLQQRIDE--------------FDA 11083
Query: 1355 SMEMQCSKL-KDELEEERGKISENLERI------SKLQKMNNELAERSKSQNSIXXXXXX 1513
+ Q L K E+EEER + E RI ++LQ++ E E + + +
Sbjct: 11084 QVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRV------ 11137
Query: 1514 XXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLS 1693
+V M +L ++ ++ S ID ++ +++ I + L
Sbjct: 11138 --------------IVEME-REELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLE 11182
Query: 1694 NQKFEIEKSQKVLQSFESHIEKLVNDS---LHEVDSAFCSLNSRFYSLIHKVDNSGETLR 1864
K EI ++ ++ S ++ + + H+++++ L+ KV+ + +R
Sbjct: 11183 KMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENS----KEIVQKLMVKVEEQRKDIR 11238
Query: 1865 AFVKNIQ-NQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEF 2041
+ + + ++ EQ + Q K +L+ N+ ++ ++++E + E
Sbjct: 11239 LQKEELDIERQKIADEQGLVVQNKAKLQNE------NERIKEMDEEIKKEKETL---KEM 11289
Query: 2042 DAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQ 2221
+A E++S+ ++ + K E+ ++ +S +V + + L+++ E ++
Sbjct: 11290 EAHLRKEKEEMRSVIEETQRRKKED-LEKMSTDVNKQNQDLMNQRDLLKQ----EREEIN 11344
Query: 2222 GK-SRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSP 2398
K ++ +R A K EDL + K+ E + E+ + I+ +T +
Sbjct: 11345 HKWTQLQQRIDEFDAQVSKQKEEDL---TKQKKMEEERKSLEETKIKIIEMKTKTEPEKI 11401
Query: 2399 LRNWPKEQ------LLGHFKQSFAGLKREYE---LELQRKTEEIYDLKRLLLNEKNGLHA 2551
+ KE+ + K+ +K + E E+ + +++ D K+++ EK L
Sbjct: 11402 KKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEK 11461
Query: 2552 XXXXXXXXXXXXVAEITGKFEKVLQEN-------------KLLPVEEVQRYKMLCVLKEE 2692
E + K+ Q + + L VE ++ K + + KEE
Sbjct: 11462 MKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEE 11521
Query: 2693 L-----------------QSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHL 2821
L ++K+ + + IKE D K K + LK+ H ++E
Sbjct: 11522 LDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHLRKEKEE 11577
Query: 2822 LKHI---------ADLEAGITD-----------REIMTSVCSDVLTALFVEMVREKEFSL 2941
++ + DLE TD R+++ ++ R EF
Sbjct: 11578 MRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDA 11637
Query: 2942 SLA-TKEQETVNQKQM-SLRKMLED-KDKLLCLVGEENKEHKRQIAILEKLKEETENNPG 3112
++ KE++ QK+M RK LE+ K K++ + + E ++ EK KEE E
Sbjct: 11638 QVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKK----EKEKEEEEVMRA 11693
Query: 3113 RVFLQSEE-----------REKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEK 3259
+V ++ EE R +I+ +++ L+ + E+ K D++ S+I R++ E+
Sbjct: 11694 KVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEE 11753
Query: 3260 LNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDL 3439
+L + ++ + E++ EEL E +K + + DL
Sbjct: 11754 ERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDL 11813
Query: 3440 LIKEKEEL---NERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDL 3610
LI+ K EL NER+ + ++++ L E E++ ++S TR Q E +
Sbjct: 11814 LIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSITEETRRQKEDLEKM 11873
Query: 3611 LNSLTEEHADLKKQ---FLSATEELQSKERDLEVAMTE----TKFLKEKLLVSDENLKE 3766
+ E+ DL+ Q EE+ K + L+ + E KE+ L ++ +KE
Sbjct: 11874 STHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKE 11932
Score = 107 bits (266), Expect = 5e-20
Identities = 223/1154 (19%), Positives = 456/1154 (39%), Gaps = 85/1154 (7%)
Frame = +2
Query: 596 KKIEDLNHKIWSLEETLQYKEEVILSSHETIS-ERDRLLKDFIHEKDLMQQ-RAQETEQK 769
K IE +I E L+ ++ + S +T+ ER L K KDL +Q +Q + +
Sbjct: 2854 KDIETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHE 2913
Query: 770 LASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIV-E 946
+ + + +LE+ + LS K+ +L+ + DCF +++ D +++EE+++Q E
Sbjct: 2914 IQLAEIQKEREILEQLKLTLSKQKE-DLEKER----DCFEKEKA-DISLREELQEQSERE 2967
Query: 947 TIYVTQIQELGEEHDLLR--------LESAKYQDEI---QSLKDECHAKEMSKQAEISKL 1093
I T+++ E +L + LE+ + Q +I + K E E+ K+AE ++
Sbjct: 2968 GIGKTRVRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEK 3027
Query: 1094 SHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSE 1273
E +N E + + N +++ ++R++ + L S D L E
Sbjct: 3028 QRRDIEKDRRNNEEMVIKLQ---NEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKE 3084
Query: 1274 -------------CNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERG-- 1408
K E + +++ SK K++LE+ER
Sbjct: 3085 RFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCF 3144
Query: 1409 -------KISENLERISKLQKMNN-------ELAERSKSQNSIXXXXXXXXXXXXXXXXX 1546
+SE+L+ S+ + ++N E+ E K++ ++
Sbjct: 3145 EKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDE 3204
Query: 1547 XXXVVNM-------AFGSKLEELTDQINI--FNSVIDKKEAEVSGHLDTISSLQTVLSNQ 1699
+ + A +KLE ++ N+ + + K V + + Q VL N
Sbjct: 3205 RDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKKDRENVESLAEELGRKQVVLENM 3264
Query: 1700 KFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKN 1879
+ E E +K +S + E+++ + V + K D + L KN
Sbjct: 3265 QIETEMQRKANESNKQMQERVLIELKKTVTDIAGA----------KEDLENQLLEEREKN 3314
Query: 1880 IQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVH--DDEFDAER 2053
Q + E+ + + K+ + D+V + + +A+++ DE +A R
Sbjct: 3315 KVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQLRLREVELEQLQALIYRQQDEIEANR 3374
Query: 2054 IALLNELKSLH-QDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKS 2230
A++NE L Q E+ + + V + + Y S KD + +
Sbjct: 3375 KAIINEKYRLEGQKTEIDRLQREVNQM----------MEYAS------KDRANLEKEKSE 3418
Query: 2231 RALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNW 2410
++H D+ G I EE+ + + D + L
Sbjct: 3419 MIAQKHQM-----------DIELNKERGLI------EERTQMLNTYEKEMDQKRTALEVE 3461
Query: 2411 PKEQLLGHFKQSFAGLK---REYELELQRKTEEIYDLKRLLLNEKNGLH--AXXXXXXXX 2575
KE L + KQ+ K ++ ++ELQR+ ++I LK NE+ L A
Sbjct: 3462 MKE--LKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKD 3519
Query: 2576 XXXXVAEITGKFE---KVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSN 2746
+AE T + + KVL E+ L +++ K L+ +S+ K+ + DS
Sbjct: 3520 DLAHLAEDTKRKDDEMKVLHESALADIQKE---------KCNLEQMRESMFKQNEMIDSE 3570
Query: 2747 SK--VLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMV 2920
K +L E ++ + Q E K I + +R MT D++T L +
Sbjct: 3571 KKKMILREDKLQQMQAEINRQQTEMDTKKSIIE-----NERAAMTKKNQDLMTEL-TKQS 3624
Query: 2921 REKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETE 3100
+ E + E+E + + L+K +E+ + L ++ ++ E LK++ E
Sbjct: 3625 EDVEIQMKEVLTEKELLESDRKLLKKDVENLQQKLLIIESDS----------ESLKQDRE 3674
Query: 3101 NNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRC 3280
L E+E +++ K L +E E++K + Q++ ++ + + +K + L+
Sbjct: 3675 -------LLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQK 3727
Query: 3281 MXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEEL-----------------KNE 3409
M LD ++ E++N +EL ++E
Sbjct: 3728 MNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLKQSE 3787
Query: 3410 IEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQ 3589
++K+ T+++ +I+ + ++L ++ ME+++ + ++ + +Q L+ + Q
Sbjct: 3788 LDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQ 3847
Query: 3590 TEKYRDLLNSLTEEHADLKK---QFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENL 3760
+ + + N L + +L++ + EE+Q++ + LE E K KE E+
Sbjct: 3848 KQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESFTHLAEDT 3907
Query: 3761 KEKDLQLRAFEIAN 3802
K++ L ++AN
Sbjct: 3908 KKEQEILDEIKVAN 3921
Score = 107 bits (266), Expect = 5e-20
Identities = 244/1167 (20%), Positives = 478/1167 (40%), Gaps = 76/1167 (6%)
Frame = +2
Query: 536 QEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKD 715
QE + +A K E ++ +KIE E +Q +++ + S E + ++ + +K
Sbjct: 7754 QELDLIQAKVVKQKEE-MVKQKIES--------EREIQQEKKKLQRSEEELEDKMQKIKR 7804
Query: 716 FIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNI------ILSLHKQIELQSQNTQSL 877
+ E L+Q ET+ K DN+M + ++D + + S K++E+ +
Sbjct: 7805 EMIELKLLQD---ETDGKRKDVDNKMRQVARKRDELEKMKADVESASKKLEVDRVMLNT- 7860
Query: 878 DCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDL------LRLESAKYQDEIQSL 1039
RDE+E + + + +++ + +LGE+ + L E+ K S
Sbjct: 7861 ---ERDELERIKTESQRATEHMQSHAEERAGDLGEKEPVNTRIQRLIQEAEKASKMAWST 7917
Query: 1040 KDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTA-EIYENTFRELGDQISQLRNDMY 1216
K H EM Q E+S ++E M++N++ + E T R + D++ R +
Sbjct: 7918 K---HEPEMRMQREVSVEEESVERQDMSANMQRMILEIEHARETLRGMKDEVQAARKE-- 7972
Query: 1217 SKNSYIDSLASRIDFLSSECN--KLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDE 1390
S ++++ +++FL+ + N K EQ S +M S+ +++
Sbjct: 7973 --RSELENM--KLEFLTMKKNMEKTYEQQNDEIQKEKQQIE-------SSKMLLSRERND 8021
Query: 1391 LEEERGKISENLERISKLQKMN----NELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXV 1558
LE+ R + E ++I L K NEL ER K+ +
Sbjct: 8022 LEQNRADL-ERQKQIMALDKQKLLAENELLEREKAD--VIKIIENLESLREEATRERATE 8078
Query: 1559 VNMAFGSKLEELTDQINIFNSVIDKKEA------EVSGHLDTISSLQTVLSNQKFEIEKS 1720
A EEL ++ S+ D +EA E+ +D + L+ L Q+ E++K+
Sbjct: 8079 TAQATRRDSEELMQKMEAL-SMEDFQEASKNQMVELKRQIDKLIELKADLLQQQTELKKT 8137
Query: 1721 QKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAV 1900
+ L+ +EK +R L H+ D +T + IQ Q
Sbjct: 8138 KADLKQQMDDLEK-----------------TRSEILKHEKDTDSKTRELELIEIQRQ--- 8177
Query: 1901 SQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALL---NE 2071
K++LE I L L ++L + E V+ + D + ++ +E
Sbjct: 8178 ----------KDDLETRIQKLTLEKRDLEVL-----RSEIVLEKKDLDQKMKQVIRKRDE 8222
Query: 2072 LKSLHQDL-----ELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQ-----EGKDGEASDVQ 2221
++ + D+ E+ + + ++ L NNV + H F L++ E ++ A+D++
Sbjct: 8223 MEKIRSDIANATEEINRERQELEILRNNVQSAR---HDFELLLERTANLEDEESAATDIE 8279
Query: 2222 G------KSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETAD 2383
K R + R+ G+ R K + VE +EK++
Sbjct: 8280 RLVLEVVKIREMVRNLKGEMERRMEKSK-----------VE---IDEKEIFK-------- 8317
Query: 2384 ASDSPLRNWPKEQLLGHFKQSFAGL----------KREYE---LELQRKTEEIYDLKRLL 2524
S ++ + ++ +G +++ GL KRE E EL K +E ++ +L
Sbjct: 8318 ---SEIQRFIQD--IGQIRENLGGLGEEIEKTRRDKRELEKMRAELAEKQQEQESMREML 8372
Query: 2525 LNEKNGLHAXXXXXXXXXXXXVAEITGKF-EKVLQENKLLPVEEVQRYKMLCVLKEELQS 2701
E+ L EI + E V+ + ++ ++Q+YK EELQS
Sbjct: 8373 HKEREELEQLKDEINREKED--VEIRRELVEAVIDKEEMKEFTDIQKYK------EELQS 8424
Query: 2702 KIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSV 2881
+ LL + ++ D + + + + + H ++ + L +L+ G E +
Sbjct: 8425 VTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFELKKG----EQLLEK 8480
Query: 2882 CSDVL--TALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEH 3055
D L VE ++ K+ SL E +N M + + ED DK + +E +E
Sbjct: 8481 QKDELKENGWIVEEIKNKKDSL-------EKIN---MEILRKNEDMDKEKGKLRQEKQEM 8530
Query: 3056 KRQIAILEKLKEETENNPGRVFLQSEE----REKIEEQKRVLDQALQ-------ECEELK 3202
+ L++ +E+ E + ++ + E R +I +K+ LDQ ++ E E+++
Sbjct: 8531 DLFRSELQRQREDLETSIQKLTHEKREMEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIR 8590
Query: 3203 NDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELR 3382
DI N +ID R+E E L ++ S+ D +L R
Sbjct: 8591 FDIANARVEIDGERQELEILRDNVQ-----------------------SARQDFERLVER 8627
Query: 3383 NYNEELKNEIEKKSTDIDLLIKEKEELNERL----AYTQKAMEQKEAVLVEK-LFEGEQK 3547
N E++ E +TDI+ L+ E ++ E + ++ ME+ + + EK +F+ E +
Sbjct: 8628 TANLEVE---ESAATDIERLVLEVVKIREMVRNLKGEMERRMEESKVEIDEKEIFKSEIQ 8684
Query: 3548 ILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFL 3727
L+ + Q RE + + + + ++L+K E+ Q +E E+ E + L
Sbjct: 8685 RLIQDIGQ--IRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQEEESMREILQKEKEEL 8742
Query: 3728 KEKLLVSDENLKEKDLQLRAFEIANSE 3808
++ L D N +++D+++ + E+ SE
Sbjct: 8743 EQ--LKKDINREKEDIEI-SRELVESE 8766
Score = 106 bits (265), Expect = 7e-20
Identities = 223/1183 (18%), Positives = 477/1183 (40%), Gaps = 92/1183 (7%)
Frame = +2
Query: 536 QEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKD 715
+EE + + K E + ++E + +I ++ L +++I E + +++ +
Sbjct: 11409 EEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDL---EKMKSE 11465
Query: 716 FIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNT----QSLDC 883
+ ++ M++ E + K+ D E H + I+ L ++E Q ++ + LD
Sbjct: 11466 IMKQRQQMEEERSELDNKIKQTDLER-HDIENSKEIVQKLMVEVEEQRKDIRLQKEELDI 11524
Query: 884 FRRDEIEDQNIKEEIEKQIV-ETIYVTQI-QELGEEHDLLRLESAKYQDEIQSLKDECHA 1057
R+ ++Q + + + ++ E + ++ +E+ +E + L+ A + E + ++
Sbjct: 11525 ERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEE 11584
Query: 1058 KEMSKQAEISKLSHTLEESIMN-SNLESLFTAEIYENTFR---------ELGDQISQLRN 1207
+ ++ ++ K+S + + + N L E E + E Q+S+ +
Sbjct: 11585 TQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKE 11644
Query: 1208 DMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEM------- 1366
+ +K ++ ++ + +++ + ++A +EM
Sbjct: 11645 EDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQ 11704
Query: 1367 ---QCSKLKDELEEERGKISENLERISK----LQKMNNELA--------ERSKSQNSIXX 1501
Q +++ E++ E+ K++++ + I + L+KM +E+ ERS+ +N I
Sbjct: 11705 IKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQ 11764
Query: 1502 XXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQ 1681
+V ++EE +I +D + +++ D + +
Sbjct: 11765 TYIEKCDIENSKEIVQKLMV------EVEEQKHEIQFQKEELDIERQKIADEQDLLIQNK 11818
Query: 1682 TVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETL 1861
+ L N+ I+ +V+ K ++L E+++ S+ + E L
Sbjct: 11819 SELQNENERIKNINEVI--------KKERETLKEMEAYLEKEKEEMKSITEETRRQKEDL 11870
Query: 1862 RAFVKNI--QNQVAVSQEQHIEHQCKEELEGHIADLV--LNDFSNDILSWSRRKEEAVVH 2029
+I Q Q SQ +E + +EE+ L +++F + S++KEE +
Sbjct: 11871 EKMSTHINEQKQDLRSQRDLLEQE-REEINHKWKQLQQRIDEFDAQV---SKQKEEDLPK 11926
Query: 2030 DDEFDAERIAL------LNELKSLHQDLELLKA---EEAVKSLSNNVGVSTKGIHYF-SQ 2179
+ E +R +L + E+K+ + E+ K EE + + V + K I SQ
Sbjct: 11927 EKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQ 11986
Query: 2180 L--IQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKL 2353
L ++ D E + + + + EDL SE EE+
Sbjct: 11987 LERVRSEMDHEQKKLNDDKKMIEQEK-----------EDLEKMKSEIMKQRQQMEEERSE 12035
Query: 2354 LAILAFETADASDSPLRNWPK--EQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLL 2527
L +T D + N + E+L+ + K+++E++ Q+ E D++R +
Sbjct: 12036 LDKKIKQT-DLEKHDIENSKEIVEKLMVEVE------KQKHEIQFQK---EELDIERQKI 12085
Query: 2528 NEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKI 2707
++ L + E+ E++ +E + L EV K KEE++S I
Sbjct: 12086 ADEQDLLIQNKIEQQNENERIKEMD---EEIKKERETLKEMEVNLQKE----KEEIESVI 12138
Query: 2708 DSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCS 2887
+ + ++ + S + E+ D + + Q + + L+ I + E S
Sbjct: 12139 EETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFE----TTS 12194
Query: 2888 DVLTALFVEMVREKEFSLSLATKEQETV----NQKQMSLRKMLEDKDKLLCLVGEENKEH 3055
++L +E E + L A KE E++ N+K+ L ++ D+ ++NK
Sbjct: 12195 NILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTELEEIEVDQS-------QQNKNV 12247
Query: 3056 KRQIAILEKLKEETENNPGRVFLQSEERE--------KIEEQKRVLDQALQECEELKNDI 3211
+ +LEK +++TE + Q+++ E K E KR LD+ + E+ N+I
Sbjct: 12248 ETMKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEI 12307
Query: 3212 QNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYN 3391
+ D++ +E+++ + K + LD +Q E++N
Sbjct: 12308 LRQRDDLE--KEKEDMMKKW--------------------------NELDGLQKEIQNQK 12339
Query: 3392 ---EELKNEIEKKSTDIDLLIKEKEELNERLAYT--------------QKAMEQKEAVLV 3520
EE+K E+E K +I IKE++ L E L +K +Q E + V
Sbjct: 12340 NEMEEIKCELETKRIEI---IKEQKRLEESLNTVNEERQYLEIVRVDYEKHQQQIEEMRV 12396
Query: 3521 EKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEEL-------Q 3679
+ E ++ L+ + R++ E+ +D++ L +E K + EEL Q
Sbjct: 12397 KTKMERDELDQLM-AKMLMDRKENERSKDMIGLLKKEMEQTKFNLDAQEEELKLEKQKIQ 12455
Query: 3680 SKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSE 3808
++++DLE+ E K ++ E EKD +AFE E
Sbjct: 12456 NEKKDLEMFKAEIKREASEVKTLKEQQLEKD--TKAFEALKEE 12496
Score = 104 bits (259), Expect = 3e-19
Identities = 222/1208 (18%), Positives = 484/1208 (40%), Gaps = 43/1208 (3%)
Frame = +2
Query: 326 AETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGLYVSNVVS 505
+E + ME + TLK L +D + ++E+ K+ L+ + +G+ V
Sbjct: 10142 SEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNV----- 10196
Query: 506 DAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHET 685
Q++E K + E +N K +I + ++ ++E L++ +
Sbjct: 10197 ----------QKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEEDLTNQKK 10246
Query: 686 ISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQN 865
+ E + L++ ++ K + + E E H + +K + +L +QI + +
Sbjct: 10247 MEEERKCLEE-VNGKIIEMKTKAELEH----------HEINQKIEELQTLQEQIMKEKEK 10295
Query: 866 TQSLDCFRRDEIED-QNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLK 1042
+++ + E ED IK E+ ++ E + + ++L ++ ++ E +++++ +K
Sbjct: 10296 AEAMTIKLKMEREDLDQIKSELVREKTEVDH--EQKKLNDDIKMIEQE----KEDLEKMK 10349
Query: 1043 DECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSK 1222
E ++ + E S+L + ++++ + + + + EI E E+ +Q +++
Sbjct: 10350 SEIMTQKQEMEKERSELDNKIQQTDLEKH-DIEKSKEIVEKLMFEVEEQRHEIQLQKEEL 10408
Query: 1223 NSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELE-- 1396
+ +A D L ++LQ + TLK ME K K+E++
Sbjct: 10409 DIERQKIADEQDLLIQNKSELQNENERIRNINEVIKKERETLK-EMEAHLEKEKEEMKSI 10467
Query: 1397 -EERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAF 1573
EE + E+LE++S K N+ + K ++ +
Sbjct: 10468 TEETRRQKEDLEKMSTDIKEQNQ--DLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQVS 10525
Query: 1574 GSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHI 1753
K E+LT Q + ++K E +T + + + + + E K +K + E +
Sbjct: 10526 KQKEEDLTKQKEMKE---ERKSLE-----ETKARIIEMKTKAELEDIKKEKEKEEEEEEM 10577
Query: 1754 EKLVNDSLHEVDSAFCSLNSRFYSLIH---KVDNSGETLRAFVKNIQNQVA--VSQEQHI 1918
V E+D L + H K+++ + + +N++ + + Q Q +
Sbjct: 10578 RVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKSEIMKQRQQM 10637
Query: 1919 EHQCKEELEGHIADLVLN--DFSND-------ILSWSRRKEEAVVHDDEFDAERIALLNE 2071
E + + ELE I + D N ++ +K E +E D ER + +E
Sbjct: 10638 EEE-RSELENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADE 10696
Query: 2072 LKSLHQDL-ELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRH 2248
L Q+ EL E +++L+ + + + +++ K+ E V ++R L+
Sbjct: 10697 QDLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKE-EIKSVSEETRRLKED 10755
Query: 2249 STGQAFREPPKPEDLYTTYSEGKIVEPHPTEE----KKLLAILAFETADASDSPLRNWPK 2416
+ + +DL ++ ++E E K+L + A S ++ PK
Sbjct: 10756 LEKMSTDVNKQNKDLM---NQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPK 10812
Query: 2417 EQLLGHFKQSFAGLKREY-ELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVA 2593
E+ + ++S K E++ + + EEI K E+ +
Sbjct: 10813 EKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELY 10872
Query: 2594 EITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLS 2773
+I + E+V E + KM+ KE+L+ ++K+ ++ + L K+
Sbjct: 10873 QIKSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKI- 10931
Query: 2774 DALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLAT 2953
++++L KH D+E +++ L VE V E+ + L
Sbjct: 10932 -----------QQTNLEKH--DIEKS-----------KEIVEKLMVE-VEEQRKDIQLQK 10966
Query: 2954 KEQETVNQKQMSLRKML-EDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQS 3130
+E + QK + +L ++K KL E++R + E++K+E E
Sbjct: 10967 EELDIERQKIADEQNLLVQNKAKL-------QNENERIKKVDEEIKKERET-------LR 11012
Query: 3131 EEREKIEEQKRVLDQALQECEELKNDIQNKHSDI-----------DSLREEQEKLNKQLR 3277
E ++++K L ++E + K D++ +DI D L +E+E++N ++
Sbjct: 11013 EMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREEINHEMT 11072
Query: 3278 CMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEEL-KNEIEKKSTDID------ 3436
+ +D ++ E+L K E+E++ ++
Sbjct: 11073 ---------------------QLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARI 11111
Query: 3437 LLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLN 3616
+ +K K EL E + ++ E++ V+VE +++ ++S R + + + LN
Sbjct: 11112 IEMKTKAELQEIMQEKEEEDEEEMRVIVEM---EREELNQIKSELKRVRSEIDHEQKKLN 11168
Query: 3617 SLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEI 3796
D KK E+L+ + ++ MT+ + ++E+ D +K+ DL+ +I
Sbjct: 11169 -------DDKKIIEQEKEDLEKMKSEI---MTQRQQMEEERSELDNKIKQTDLE--RHDI 11216
Query: 3797 ANSEKQYQ 3820
NS++ Q
Sbjct: 11217 ENSKEIVQ 11224
Score = 102 bits (255), Expect = 1e-18
Identities = 220/1188 (18%), Positives = 496/1188 (41%), Gaps = 26/1188 (2%)
Frame = +2
Query: 296 DTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVE 475
D +S+ +AE E++ I L++ +L ++ + + E+ + ++ +D +
Sbjct: 2071 DKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIR 2130
Query: 476 SGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYK 655
G+ + + + + ++ A +++ + K I+++ +++ QY
Sbjct: 2131 VGIEKQEITFKDL--------KADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQKERQYM 2182
Query: 656 EEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLAS--RDNEMMHMVLEKDNIIL 829
+ ++ + D + + E+ ++ + E EQ+ + D + EK+NII
Sbjct: 2183 DRLVEEIEKRTKALDEMQMEVDKERQEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQ 2242
Query: 830 SLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLES 1009
+ +I+ +S N E++ +NI +E TI+ EL +EH LR
Sbjct: 2243 A---EIQKESDNL---------ELQSENISKE------RTIF-----ELEKEHLGLRENE 2279
Query: 1010 AKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQ 1189
A+Y+ Q DE K ++ ++ ++ ++ E + TA E T
Sbjct: 2280 AEYK---QKQIDELQNKLRMEKVQVEQMQ--ADKDQQRKKAEYVKTARGRETT------A 2328
Query: 1190 ISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQ 1369
+ + R +M +SL + + + + EQ +K E +
Sbjct: 2329 LEEQRQEM-------ESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKYKE-K 2380
Query: 1370 CSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXX 1549
K ++L+ +R + ++++ ++ E ER K + I
Sbjct: 2381 LDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEI---QKPAVYTETYMLETQ 2437
Query: 1550 XXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKV 1729
VV + +L+E+ +IN S ++K+++ + IS ++ + EK +
Sbjct: 2438 KPVVEKSKTDELDEVRKKINADLSEVEKQKSALVQMNLKISQEESYVKK-----EKDRLK 2492
Query: 1730 LQSFESHIE-KLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQ 1906
LQ E +++ +N +E+D + + L + +D + + +V +++
Sbjct: 2493 LQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMD----------RLEKEKVEITK 2542
Query: 1907 EQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLH 2086
E+ ++ + E++ A S D++ K+E + D + R L EL+ +
Sbjct: 2543 EKQRVNEMQNEVKRKNA-------SVDLI-----KQEVLREQDHIENSREILNRELEKIK 2590
Query: 2087 QDLELLKAE-EAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRAL---RRHST 2254
+ +L E EA+ +G + + +Q+ EA D + + R + RR++
Sbjct: 2591 EKKTILAEEFEALDDKKEMIGKEMQRLGKMKAELQK----EAEDTEKQRRDIDNDRRNNE 2646
Query: 2255 GQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGH 2434
+ + +D+ T+ + E + +K+ L +T + L E +
Sbjct: 2647 EMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLE-SDRDTLEKERFDLEKTKTE--MKD 2703
Query: 2435 FKQSFAGLKREYEL---ELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITG 2605
++ R++E+ E+Q++ E + LK L +K L A+I+
Sbjct: 2704 LEKQLESQSRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEK----ADISL 2759
Query: 2606 KFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSN--SKVLAEKLSDA 2779
+ E Q K E + + ++ +K+E+ + L +KE ++N K + E D
Sbjct: 2760 REELEEQSEK----EGIDKTRVR--IKQEMDELEQTRLNVVKELENNELQKQIIEDERDK 2813
Query: 2780 LKKSADHAQRES-HLLKHIADLEAGITDREIMT----SVCSDVLTALFVEMVREKEFSLS 2944
+++ Q+E+ K D+E + E M + D+ T+ + +R++E +L
Sbjct: 2814 IEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETS--TDRIRDEEANLR 2871
Query: 2945 LATK----EQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPG 3112
+ + +++T+ +++ L+K + L + +N++H+ Q+A ++K
Sbjct: 2872 VLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQK---------- 2921
Query: 3113 RVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXX 3292
ERE +E+ K L + ++ E+ ++ + + +DI SLREE ++ +++
Sbjct: 2922 -------EREILEQLKLTLSKQKEDLEKERDCFEKEKADI-SLREELQEQSER------- 2966
Query: 3293 XXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELK-NEIEKKSTDIDLLIKEKEELNE 3469
I +D ++ N +EL+ NE++K+ ++ E++++ +
Sbjct: 2967 --------EGIGKTRVRIKKEMDELKQTRLNVVKELENNELQKQ-----IIEDERDKIEQ 3013
Query: 3470 RLAYTQKAME--QKEAVLVEK-LFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHAD 3640
A QK E +K+ +EK E+ ++ L++ + T++ RD E + +
Sbjct: 3014 IKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETSTDRIRD-----EEANLE 3068
Query: 3641 LKKQFLSATEELQSKER-DLEVAMTETKFLKEKLLVSDENLKEKDLQL 3781
++KQ L + + KER DLE TE LK++L + +++ ++QL
Sbjct: 3069 VQKQRLESDRDTLEKERFDLEKTKTEMGNLKKQL---ESQIRQHEIQL 3113
Score = 101 bits (252), Expect = 2e-18
Identities = 227/1221 (18%), Positives = 499/1221 (40%), Gaps = 47/1221 (3%)
Frame = +2
Query: 257 SVTSFIEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLE 436
SVT + + LD S + +T+E + I G L+ + F+L + LLE
Sbjct: 8424 SVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFELKKGEQ----LLE 8479
Query: 437 DIRNTKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLN 616
KD L E+G V EE K + + N + +K ED++
Sbjct: 8480 ---KQKDELK--ENGWIV-----------------EEIKNKKDSLEKINMEILRKNEDMD 8517
Query: 617 HKIWSLEETLQYKEEVILSSHETISERDRL---LKDFIHEKDLMQQRAQETEQKLASRDN 787
+ L Q K+E+ L E +R+ L ++ HEK M+ E + D
Sbjct: 8518 KEKGKLR---QEKQEMDLFRSELQRQREDLETSIQKLTHEKREMEVLRSEIVLEKKDLDQ 8574
Query: 788 EMMHMVLEKDNI------ILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVET 949
+M ++ ++D + I + +I+ + Q + L RD + Q+ +++ E+ + T
Sbjct: 8575 KMKQVIRKRDEMEKIRFDIANARVEIDGERQELEIL----RDNV--QSARQDFERLVERT 8628
Query: 950 IYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSN 1129
+ + + + L LE K ++ +++LK E + + EI +
Sbjct: 8629 ANLEVEESAATDIERLVLEVVKIREMVRNLKGEMERRMEESKVEIDE------------- 8675
Query: 1130 LESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLA---SRIDFLSSECNKLQEQXX 1300
EI+++ + L I Q+R ++ + I++ S ++ + +E + Q++
Sbjct: 8676 ------KEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQE-- 8727
Query: 1301 XXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSK 1480
+ SM K K+ELE+ + I+ E I +++ EL E
Sbjct: 8728 ----------------EESMREILQKEKEELEQLKKDINREKEDI----EISRELVESEI 8767
Query: 1481 SQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHL 1660
+ + + +L+ +T+++ +++ ++V +
Sbjct: 8768 YEGEVKGFTDV-----------------QKYKEELQIVTEELLTKKRNLEQLNSDVQHLM 8810
Query: 1661 DTISSLQTVLSNQKFEIE----KSQKVLQSFESHIEKLVNDS--LHEVDSAFCSLNSRFY 1822
T+ + +K E+E + QK Q E +KL + + E++ +L S
Sbjct: 8811 QTLEEVDIQYIKKKAELEHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINM 8870
Query: 1823 SLIHK---VDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDIL 1993
++ K ++ E LR + + Q Q ++E+E L++ +
Sbjct: 8871 EILQKREDMEKEKENLRREKQETELFRGELQRQ------RDEVESSRQALIMEKDQFKLK 8924
Query: 1994 SWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYF 2173
+R E + + E L+++ DLE +A+ A +SL++ + K
Sbjct: 8925 IDHQRNEMSAAFEKEH--------KRLENMENDLENQRAKLA-ESLNDAAKMEQKLQQMK 8975
Query: 2174 SQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKL 2353
++L +E + E K+ ++ + R+ + +I + H +KK
Sbjct: 8976 NELNKEKEQVEEMKQMVKTERVKIEQEKEEMRKQTQ-----------EIEDGHEKLQKKT 9024
Query: 2354 -LAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELE---LQRKTEEIYDLKRL 2521
+A + A++ L++ + L +Q E E + L R + E+ D K
Sbjct: 9025 EIADKLLQDANSESDRLKDLSMK--LQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIR 9082
Query: 2522 LLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQS 2701
L N+++ + + K E++++E + L + +Q+ + + K ++++
Sbjct: 9083 LKNDRDAYEKD-----------MTHLELKREELVRETEDLERKILQQREQDEMAKRDIEN 9131
Query: 2702 KIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSV 2881
+ ++L E+ + D +L ++ A + H++R+ LL L+ + +E
Sbjct: 9132 QTEAL--EVMKVD----ILKKRNEFAKEMENVHSERQKLLL-----LQGALQSQE----- 9175
Query: 2882 CSDVLTALFVEMVREKEFSLSLATKEQ---------ETVNQKQMSLRKMLEDKDKLLCLV 3034
S++ +F+E +K + A E+ ETV +Q RK++E+ +
Sbjct: 9176 -SELENRVFME--EQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQR----E 9228
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVFLQSE----EREKIEEQKRVLDQALQECEELK 3202
E+ + K QI E+ K++ +N + Q E E+ +E++K L++ E +E++
Sbjct: 9229 KEQLEISKNQI---EQEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQ 9285
Query: 3203 NDIQNKHSDIDS----LREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQ 3370
N I+ + D+++ + E++++ ++ R + + +
Sbjct: 9286 NAIRKEREDLENCWVEIEGEKKRMEEETRRLEMHR------------------EEIKKVD 9327
Query: 3371 LELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKI 3550
EL+ E +++ EK + ++ L++ K E+ +K ++ + ++
Sbjct: 9328 SELQKSRENIESREEKINNKMEELLQMKVEMGRTKEEIEKESQRLQDATID--------- 9378
Query: 3551 LLLESSQSATREQTEKYRDLLN-SLTEEHADLKKQFLSAT----EELQSKERDLEVAMTE 3715
LE++++ + Q +K+ D+++ + E+ ++K Q T EE++ K +DLE+ M +
Sbjct: 9379 --LENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQLDKETKRLSEEIELKVKDLEMEMAD 9436
Query: 3716 TKFLKEKLLVSDENLKEKDLQ 3778
K K++ + + L EK+ Q
Sbjct: 9437 MKRQKQE-IEDTKGLLEKEKQ 9456
Score = 99.8 bits (247), Expect = 9e-18
Identities = 238/1239 (19%), Positives = 502/1239 (40%), Gaps = 68/1239 (5%)
Frame = +2
Query: 302 RKSLETKIAE-TLERMEIHEGDTANTLKNMNFD------------LGQDNPGVPGLLEDI 442
+ LET+I + TLE+ ++ + L+ + D + + + E+I
Sbjct: 8178 KDDLETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANATEEI 8237
Query: 443 RNTKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNK-KIEDLNH 619
+ L+ + + + + + +L + ++EE AA D E +L KI ++
Sbjct: 8238 NRERQELEILRNNVQSARHDFELLLERTANLEDEES----AATDIERLVLEVVKIREMVR 8293
Query: 620 KIWSLEETLQYKEEVILSSHETI-SERDRLLKDFIHEKDLMQQRAQETEQ-KLASRDNEM 793
+ E K +V + E SE R ++D ++ + +E E+ + R+ E
Sbjct: 8294 NLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEK 8353
Query: 794 MHMVL-EKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQ 970
M L EK S+ + + + + + L +DEI + EI +++VE V +
Sbjct: 8354 MRAELAEKQQEQESMREMLHKEREELEQL----KDEINREKEDVEIRRELVEA--VIDKE 8407
Query: 971 ELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQ---AEISKLSHTLEESIMNSNLESL 1141
E+ E D+ KY++E+QS+ +E K+ +++ L T+EE + +
Sbjct: 8408 EMKEFTDI-----QKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKR- 8461
Query: 1142 FTAEIYENTFR-ELGDQISQLRNDMYSKNSYI-DSLASRIDFLSSECNKLQEQXXXXXXX 1315
AE+ F + G+Q+ + + D +N +I + + ++ D L K+ +
Sbjct: 8462 --AELEGIGFELKKGEQLLEKQKDELKENGWIVEEIKNKKDSLE----KINMEILRKNED 8515
Query: 1316 XXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSI 1495
K M++ + EL+ +R E+LE + +QK+ +E E ++ I
Sbjct: 8516 MDKEKGKLRQEKQEMDL----FRSELQRQR----EDLE--TSIQKLTHEKREMEVLRSEI 8565
Query: 1496 XXXXXXXXXXXXXXXXXXXXVVNMAFG------------SKLEELTDQINIFNSVIDKKE 1639
+ + F +LE L D + ++
Sbjct: 8566 VLEKKDLDQKMKQVIRKRDEMEKIRFDIANARVEIDGERQELEILRDNVQSARQDFERL- 8624
Query: 1640 AEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSA--FCSLNS 1813
E + +L+ S T + E+ K ++++++ + +E+ + +S E+D F S
Sbjct: 8625 VERTANLEVEESAATDIERLVLEVVKIREMVRNLKGEMERRMEESKVEIDEKEIFKSEIQ 8684
Query: 1814 RFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLV------LND 1975
R I ++ + L+ ++N + + ++ E + K++ E + +++ L
Sbjct: 8685 RLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQEEESMREILQKEKEELEQ 8744
Query: 1976 FSNDILSWSRRKEEAVVHDDEFDAE----RIALLNELKSLHQDLELLKAEEAVKSLSNNV 2143
DI +R KE+ + + ++E + +++ ++L+++ E K N+
Sbjct: 8745 LKKDI---NREKEDIEISRELVESEIYEGEVKGFTDVQKYKEELQIVTEELLTKK--RNL 8799
Query: 2144 GVSTKGIHYFSQLIQEGKDGEASDVQG-KSRALRRHSTGQAFREPPKPEDLYTTYSEGKI 2320
+ + Q ++E D+Q K +A H T + + E E
Sbjct: 8800 EQLNSDVQHLMQTLEE------VDIQYIKKKAELEHITSEIQKREQILEKQKKKLEENGW 8853
Query: 2321 VEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYEL---ELQRK 2491
+ EE +++ + T ++ + + K + + K++ K+E EL ELQR+
Sbjct: 8854 I----IEEIEMMKV----TLESINMEILQ--KREDMEKEKENLRREKQETELFRGELQRQ 8903
Query: 2492 TEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKM 2671
+E+ ++ L+ EK+ +F+ + QR +M
Sbjct: 8904 RDEVESSRQALIMEKD----------------------QFKLKIDH---------QRNEM 8932
Query: 2672 LCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAG 2851
++E +++++ +++ + + LAE L+DA K Q ++ L K +E
Sbjct: 8933 SAAFEKE-HKRLENMENDLENQRAK---LAESLNDAAKMEQKLQQMKNELNKEKEQVEE- 8987
Query: 2852 ITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCL 3031
++ V++ +EKE + T+E E ++K L+K E DKLL
Sbjct: 8988 ----------MKQMVKTERVKIEQEKE-EMRKQTQEIEDGHEK---LQKKTEIADKLLQD 9033
Query: 3032 VGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEE----L 3199
E+ K L+ +++ E ++E +KR LD+ +E ++ L
Sbjct: 9034 ANSESDRLKDLSMKLQMQRQDIEKT----------NTEMETKKRSLDRMSRELQDDKIRL 9083
Query: 3200 KNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLEL 3379
KND D+ L ++E+L ++ + +L+ L+
Sbjct: 9084 KNDRDAYEKDMTHLELKREELVRE-------------------------TEDLERKILQQ 9118
Query: 3380 RNYNEELKNEIEKKSTDIDLL-----------IKEKEELN---ERLAYTQKAMEQKEAVL 3517
R +E K +IE ++ ++++ KE E ++ ++L Q A++ +E+ L
Sbjct: 9119 REQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQESEL 9178
Query: 3518 VEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDL 3697
++F EQK L + +TE+ R L ++E + ++ EELQ ++ L
Sbjct: 9179 ENRVFMEEQKHL------KQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQREKEQL 9232
Query: 3698 EVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQ 3814
E++ + + K+ L NL E+ L+ E AN E +
Sbjct: 9233 EISKNQIEQEKKDLQNMKSNL-ERQLESLRHEKANVEDE 9270
Score = 99.4 bits (246), Expect = 1e-17
Identities = 249/1367 (18%), Positives = 536/1367 (39%), Gaps = 195/1367 (14%)
Frame = +2
Query: 296 DTRKSLETKIAETLERMEIH----EGDTANTLK---NMNFDLGQDNPGVPGLLEDIRNTK 454
D K L+T++ + ++++ E + A ++ NM +L + + V +++I K
Sbjct: 5918 DELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEIQMKEILTEK 5977
Query: 455 DLLDTVESGLY--VSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIW 628
+LL L V N+ + + + K A ++E + + DL +
Sbjct: 5978 ELLHNDRKLLTRDVENLQQKLI---DLERDSKRLKLDREAFENEKEAMKQMKTDLQIQAD 6034
Query: 629 SLE----ETLQYKEEVILSSHETISERDRL--LKDFIHEKDL-MQQRAQETEQKLASRDN 787
+E ET ++ V + + ERD++ L + + KD+ + ++ ++ E+K+ S +
Sbjct: 6035 EIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQS 6094
Query: 788 EMMHMVLEKDNI------ILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVET 949
+ + E+ N+ + + + +E Q +NT + R+++E N E I +++ E
Sbjct: 6095 DKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKMN--ENITREMHEI 6152
Query: 950 IYVT-QIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMS----KQAEISKLSHTLEES 1114
+ Q+ + +E D L+ E Q E++ K E K+ S +Q+E+ K +++
Sbjct: 6153 KHQEEQMNQKQDELDQLKTEIQNLQQELEKEK-EIIMKDRSQFDLRQSELDK-----QQT 6206
Query: 1115 IMNSNLESLFTAEIYENTFRELG---DQISQLRNDMYSKNSYIDSLASRIDFLSSECNKL 1285
MN +E++ +N ++L +++ + + +M + D +D + KL
Sbjct: 6207 NMNDIMETM------KNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLD-KDLKMMKL 6259
Query: 1286 QEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNEL 1465
Q+Q +A + K+K+E + ER + + E + K ++ L
Sbjct: 6260 QKQVFEEEKNKLEQMKIELEREAD---EIRKIKEETQNERQSLEKMTEELKKEKESFTHL 6316
Query: 1466 AERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAE 1645
AE +K + I S LEE+ + I+ ++ K+
Sbjct: 6317 AEDTKKEQEILDKVKVANESLMADLQKEK--------SNLEEMRENISKQTEDVENKKEN 6368
Query: 1646 VSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEV-----DSAFCSLN 1810
+ D + LQ + Q+ EIEK + ++S + I K V D H++ DS L+
Sbjct: 6369 LRLREDELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLD 6428
Query: 1811 SRFYSLIHKVDNSGETLRAFVKNIQNQV----AVSQEQHIEHQCKEELEGHIADLVLND- 1975
+ +N E L+ ++ + + E E Q EE+ + + N+
Sbjct: 6429 REAF------ENEREVLKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNER 6482
Query: 1976 --FSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAE------------ 2113
+ + +K+E D+ D R +L +LK + ++L+ E
Sbjct: 6483 KQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLE 6542
Query: 2114 ---EAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTG--------- 2257
+ + + + + + ++E ++ A +++ K++ L +
Sbjct: 6543 READEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLADLQ 6602
Query: 2258 ------QAFRE--PPKPEDLYTTYSEGKIVEPH----PTEEKKLLAILAFETADA-SDSP 2398
+ RE + ED+ + K+ E TE +K + + E + S+
Sbjct: 6603 KEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERA 6662
Query: 2399 LRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXX 2578
K+ ++ K K+ ++E+Q K EI K LL N++N L
Sbjct: 6663 AMIREKQNMMTELK------KKSEDVEMQMK--EILTEKELLHNDRNLLKKDVEDLQQKL 6714
Query: 2579 XXXVAEITG-KFEKVLQEN----------------------KLLPVEEVQRYKMLCVLKE 2689
+ K +K EN KL E QR + +
Sbjct: 6715 MSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQ 6774
Query: 2690 ELQSKIDSLLKEIKEK-----DSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGI 2854
+ + +I++L++EIK+K +S +++ EK + +S D + +S K ++E +
Sbjct: 6775 KEREEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRS-DLEKAKSQTFKQNKNIEIAL 6833
Query: 2855 TDREIMTSVCSDVLTALFVEMVR--EKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLC 3028
+ + + + + + ++ +++ + LA +E E ++ +++ E KD LL
Sbjct: 6834 AEIQQKRNALEKMSKEISRDRMKLEDEKKEIQLAREELERMHG---DMQRQQEAKDHLLS 6890
Query: 3029 LVGEENKEHKRQIAILEKLKEETENNPGR-----------VFLQS--------------- 3130
+ +E+ K + I+ + + + P R VF+Q
Sbjct: 6891 GITDESLLKKSEAEIVLQPSQVDKAKPARKTEISDSDKQPVFVQQMPEMDLKDALKKDFE 6950
Query: 3131 ---------------------------EEREKIEEQKRVLDQALQECEELKNDIQNKHSD 3229
+E +K+++ + L + + E+ K D+QN+
Sbjct: 6951 SEKLDLPKVKDVLPQDQQMKLEQKLIEDEMDKLKQMRAELQKEADQIEKKKQDMQNERQK 7010
Query: 3230 IDSL-------REEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNY 3388
+D + R E+LN+++ ++ + ++ E+
Sbjct: 7011 LDDMAARLQEERRTNERLNEEINIQKVNQQKQATAFQME-------KTDFERIKTEIDQA 7063
Query: 3389 NEELKNEIEKKSTDIDLLIKEKEELNERLAYTQK-------------AMEQKEAVLVEKL 3529
N+EL ++ EK I + KE+E L E A K + E + A L E +
Sbjct: 7064 NKELADQQEKNKKTITEMQKERETLEEMRANISKQVETITNENKSLSSRESELAKLQEDI 7123
Query: 3530 FEGEQKILLLESS---QSATREQTEKYRDLLNSLTEEHADLKKQFLSATE----ELQSKE 3688
+ +Q++ L+++ + +Q + DLL ++ D K ++ E E+ ++
Sbjct: 7124 LQQQQEMDELKNTIMMEMCQLDQRQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQT 7183
Query: 3689 RDLEVAMTETKFLKEKL------LVSDENLKEKDLQLRAFEIANSEK 3811
R+++ M K KE L +++L EK+ +L + +++K
Sbjct: 7184 RNIKSDMVSLKMEKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDK 7230
Score = 99.0 bits (245), Expect = 1e-17
Identities = 237/1220 (19%), Positives = 485/1220 (39%), Gaps = 57/1220 (4%)
Frame = +2
Query: 305 KSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGL 484
K + +IAE L+++ GD +N +L ++ + + + ++ +D+ + L
Sbjct: 1961 KKSQDEIAEQLKQV----GDMMQFTQNEKDNLDRERAAI--IEQKLQMERDMTHLLNREL 2014
Query: 485 YVSNVVSDAVLNGVVSAQE------------EEFKEALAAKDSENFLLNKKIEDLNHKIW 628
+V VLN ++ E+ K L + E L + I + K+
Sbjct: 2015 ESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLE 2074
Query: 629 SLEETLQYKEEVILSSHETISERDRLLKDFIH---EKDLMQQRAQETEQKLASRDNEMMH 799
S+ +TL E + +T++E+ +L + E+D + A+ET++K D + +
Sbjct: 2075 SVLQTLAEDTEKLRI--DTLAEKQKLEDAAVELQKERDEIMNIAEETKRK--REDVDKIR 2130
Query: 800 MVLEKDNIILS-----LHKQIELQSQNTQSLDCFRRD--EIEDQNIKEEIEKQIVETIYV 958
+ +EK I L K+ + Q++ ++D ++D ++ + E+Q ++ + V
Sbjct: 2131 VGIEKQEITFKDLKADLQKEAAIVENQRQAV---QKDIQNVKDMEVQIQKERQYMDRL-V 2186
Query: 959 TQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSK------------------QAEI 1084
+I++ + D +++E K + E++S +DE +E SK QAEI
Sbjct: 2187 EEIEKRTKALDEMQMEVDKERQEVESKRDELE-QETSKLREDEDEFSRQKEKNNIIQAEI 2245
Query: 1085 SKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLR-NDMYSKNSYIDSLASRIDF 1261
K S LE + + N+ E T EL + LR N+ K ID L +++
Sbjct: 2246 QKESDNLE--LQSENISK-------ERTIFELEKEHLGLRENEAEYKQKQIDELQNKLRM 2296
Query: 1262 LSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISK 1441
+ ++Q +K + + + L+++ +E + E E + K
Sbjct: 2297 EKVQVEQMQADKDQQRKKAEY-------VKTARGRETTALEEQ-RQEMESLREEYENVEK 2348
Query: 1442 LQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNS 1621
+K NE E +S+ + E+L Q +F
Sbjct: 2349 QKKHVNEQKELFESRMKSLEMENEAMKKYKEK-----------LDKEYEDLQFQRQLFEK 2397
Query: 1622 VIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFC 1801
I + E+ + I + L QK + +L++ + +EK D L EV
Sbjct: 2398 EIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDEV----- 2452
Query: 1802 SLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFS 1981
+ + + +V+ L +Q + +SQE+ + K+ L+ L N+ +
Sbjct: 2453 --RKKINADLSEVEKQKSAL------VQMNLKISQEESYVKKEKDRLK-----LQENEQN 2499
Query: 1982 NDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQD-LELLKAEEAVKSLSNNVGVSTK 2158
+ + ++ E E + ++ L N + L ++ +E+ K ++ V + N V
Sbjct: 2500 MQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITKEKQRVNEMQNEVKRKNA 2559
Query: 2159 GIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPT 2338
+ Q + +D ++ L R E
Sbjct: 2560 SVDLIKQEVLREQD----HIENSREILNR--------------------------ELEKI 2589
Query: 2339 EEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKR 2518
+EKK + FE D K++++G Q +K E LQ++ E+ +R
Sbjct: 2590 KEKKTILAEEFEALD---------DKKEMIGKEMQRLGKMKAE----LQKEAEDTEKQRR 2636
Query: 2519 LLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQ 2698
+ N++ V ++ + + + + EE L V K+ L+
Sbjct: 2637 DIDNDRRN-----------NEEMVIKLQNEKKDIETSTDRIRDEEAN----LRVQKQRLE 2681
Query: 2699 SKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTS 2878
S D+L KE + + + + L+K Q ES +H L +REI
Sbjct: 2682 SDRDTLEKERFDLEKTKTEMKD-----LEK-----QLESQSRQHEIQLVEIQKEREI--- 2728
Query: 2879 VCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQ--MSLRKMLEDKDKLLCLVGEENKE 3052
L L + + ++KE KE++ +++ +SLR+ LE++ + + +
Sbjct: 2729 -----LEQLKINLSKQKED----LEKERDCFEKEKADISLREELEEQSEKEG-IDKTRVR 2778
Query: 3053 HKRQIAILEKLK----EETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNK 3220
K+++ LE+ + +E ENN + + +ER+KIE+ K L + ++ E+ + DI+N
Sbjct: 2779 IKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIEND 2838
Query: 3221 HSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEEL 3400
+ + + + + K + L+ + +L+ N E+
Sbjct: 2839 RRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEM 2898
Query: 3401 KN-----EIEKKSTDIDLL-IKEKEELNERLAYTQKAMEQKEAVLVEK-LFEGEQKILLL 3559
K+ E + + +I L I+++ E+ E+L T +QKE + E+ FE E+ + L
Sbjct: 2899 KDLEKQLESQNRQHEIQLAEIQKEREILEQLKLT--LSKQKEDLEKERDCFEKEKADISL 2956
Query: 3560 --ESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKE 3733
E + + RE K R + +E +LK+ L+ +EL++ E ++ E +++
Sbjct: 2957 REELQEQSEREGIGKTR---VRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQ 3013
Query: 3734 KLLVSDENLKEKDLQLRAFE 3793
+ ++ + Q R E
Sbjct: 3014 IKAELQKEAEDTEKQRRDIE 3033
Score = 94.4 bits (233), Expect = 4e-16
Identities = 243/1244 (19%), Positives = 500/1244 (40%), Gaps = 68/1244 (5%)
Frame = +2
Query: 293 LDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTV 472
+ T+ + KI+E + + + + +K +DL Q + D+ + + +
Sbjct: 1897 IKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQ-------MQTDLNRQQKEMQDI 1949
Query: 473 ESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQY 652
++ +++ + + +Q+E ++ D F N+K + +E+ LQ
Sbjct: 1950 QNAVFMEK-------SELKKSQDEIAEQLKQVGDMMQFTQNEKDNLDRERAAIIEQKLQM 2002
Query: 653 KEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILS 832
+ ++ + + + K+ ++EK L++ + + +D E M + LE++
Sbjct: 2003 ERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRDM--QDLEQMKINLEREK---- 2056
Query: 833 LHKQIELQSQNTQSLDCFRRDEIED--QNIKEEIEKQIVETIYVTQIQELGEEHDLLRLE 1006
++++LQ Q+ +D++E Q + E+ EK ++T+ + Q+L + +E
Sbjct: 2057 --EEMQLQRQSIAE----EKDKLESVLQTLAEDTEKLRIDTL--AEKQKLEDA----AVE 2104
Query: 1007 SAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLE-ESIMNSNLESLFTAE--IYENTFRE 1177
K +DEI ++ +E K + ++ K+ +E + I +L++ E I EN +
Sbjct: 2105 LQKERDEIMNIAEETKRK----REDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQA 2160
Query: 1178 LGDQISQLRN---DMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTL 1348
+ I +++ + + Y+D L I+ + +++Q +
Sbjct: 2161 VQKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVD---------------- 2204
Query: 1349 KASMEMQCSKLKDELEEERGKISENLERISKLQKMNNEL-AERSKSQNSIXXXXXXXXXX 1525
K E++ + DELE+E K+ E+ + S+ ++ NN + AE K +++
Sbjct: 2205 KERQEVESKR--DELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKE 2262
Query: 1526 XXXXXXXXXXV---VNMA--FGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVL 1690
+ N A +++EL +++ + +++ +A+ ++T
Sbjct: 2263 RTIFELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTAR 2322
Query: 1691 SNQKFEIEKSQKVLQSFESHIE------KLVNDSLHEVDSAFCSL---NSRFYSLIHKVD 1843
+ +E+ ++ ++S E K VN+ +S SL N K+D
Sbjct: 2323 GRETTALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKYKEKLD 2382
Query: 1844 NSGETL----RAFVKNIQNQVAVSQ--EQHIEHQCKE--------ELEGHIADL---VLN 1972
E L + F K IQ Q ++IE + KE E ++ + V+
Sbjct: 2383 KEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVE 2442
Query: 1973 DFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVS 2152
D L R+K A + + E + +N LK ++ + K ++ +K N +
Sbjct: 2443 KSKTDELDEVRKKINADLSEVEKQKSALVQMN-LKISQEESYVKKEKDRLKLQENEQNMQ 2501
Query: 2153 TKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPH 2332
SQL K E + Q + +R + + + E + T + ++ E
Sbjct: 2502 ------MSQL--NAKQNELDERQAEMEKQKREL--ENVMDRLEKEKVEITKEKQRVNEMQ 2551
Query: 2333 PTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKT------ 2494
++K ++ D + +EQ H + S L RE E ++KT
Sbjct: 2552 NEVKRKNASV---------DLIKQEVLREQ--DHIENSREILNRELEKIKEKKTILAEEF 2600
Query: 2495 EEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKML 2674
E + D K ++ E L AE+ + E ++ + + + +M+
Sbjct: 2601 EALDDKKEMIGKEMQRL-----------GKMKAELQKEAEDTEKQRRDIDNDRRNNEEMV 2649
Query: 2675 CVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLS---DALKKSADHAQRESHLLKHIADLE 2845
L+ E + I++ I+++++N +V ++L D L+K ++ +K DLE
Sbjct: 2650 IKLQNE-KKDIETSTDRIRDEEANLRVQKQRLESDRDTLEKERFDLEKTKTEMK---DLE 2705
Query: 2846 AGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLL 3025
+ + R+ E L KE+E + Q +++L K ED +K
Sbjct: 2706 KQLESQS------------------RQHEIQLVEIQKEREILEQLKINLSKQKEDLEKER 2747
Query: 3026 CLVGEENKEHKRQIAILEKLKEETEN---NPGRVFLQSE-------------EREKIEEQ 3157
+E K I++ E+L+E++E + RV ++ E E E E Q
Sbjct: 2748 DCFEKE----KADISLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQ 2803
Query: 3158 KRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXX 3337
K++++ + E++K ++Q + D + R++ E + M
Sbjct: 2804 KQIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRI 2863
Query: 3338 XXISSNLDSMQLELRNYNEELKNE---IEKKSTDIDLLIKEKEELNERLAYTQKAMEQKE 3508
+NL ++ L + + L+ E ++K +T++ L K+ E N R Q A QKE
Sbjct: 2864 RDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQN-RQHEIQLAEIQKE 2922
Query: 3509 AVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKE 3688
++E+L K+ L S +E EK RD +E AD +S EELQ +
Sbjct: 2923 REILEQL-----KLTL-----SKQKEDLEKERDCFE---KEKAD-----ISLREELQEQS 2964
Query: 3689 RDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQYQ 3820
+ T + KE + LK+ L + E+ N+E Q Q
Sbjct: 2965 EREGIGKTRVRIKKEM-----DELKQTRLNV-VKELENNELQKQ 3002
Score = 94.0 bits (232), Expect = 5e-16
Identities = 221/1220 (18%), Positives = 488/1220 (40%), Gaps = 53/1220 (4%)
Frame = +2
Query: 284 DGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLL 463
DG + + ++ E+L + +GD L+ M D + + + + + + L
Sbjct: 9964 DGKRNEINKEQQRLEESLRAINEEKGD----LEIMRADYEKQEQQIEEMRVEAKMERKEL 10019
Query: 464 DTVESGLYVSNVVSD---AVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSL 634
D ++S L D LN + E+E + L SE +++ED
Sbjct: 10020 DQIKSELEKDKTEIDYEWKKLNNDRNMIEKE-RNDLEKMKSELMTQRQQMED-------- 10070
Query: 635 EETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEK 814
+ E+ E +E+D++ K+ K+++++ E E++ + + LE+
Sbjct: 10071 -----ERSELDQKIKEANTEKDKIEKN----KEIVERLMAEVEEQRNDFKLKKEELALER 10121
Query: 815 DNII----LSLHKQIELQSQNTQ----------SLDCFRRDEIEDQNIKEEIEKQIVETI 952
NI+ L + ELQ+++ Q + + E Q K+EI+ I ET
Sbjct: 10122 QNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETS 10181
Query: 953 YVTQ-IQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSN 1129
+ ++++ ++ + E +D ++ ++E + K Q I + + + +
Sbjct: 10182 RQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQ-KEED 10240
Query: 1130 LESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXX 1309
L + E E+ +I +++ ++ I+ + L + K +E+
Sbjct: 10241 LTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAMT 10300
Query: 1310 XXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISK----LQKMNNELA--- 1468
+K+ + + K E++ E+ K++++++ I + L+KM +E+
Sbjct: 10301 IKLKMEREDLDQIKSELVRE----KTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQK 10356
Query: 1469 -ERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAE 1645
E K ++ + V + F ++EE +I + +D + +
Sbjct: 10357 QEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMF--EVEEQRHEIQLQKEELDIERQK 10414
Query: 1646 VSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYS 1825
++ D + ++ L N+ I +V+ K ++L E+++ S
Sbjct: 10415 IADEQDLLIQNKSELQNENERIRNINEVI--------KKERETLKEMEAHLEKEKEEMKS 10466
Query: 1826 LIHKVDNSGETLRAFVKNI--QNQVAVSQEQHIEHQCKEELEGHIADLV--LNDFSNDIL 1993
+ + E L +I QNQ + Q +E + KE++ L +++F +
Sbjct: 10467 ITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQE-KEDINHEWTQLQQRIDEFDAQV- 10524
Query: 1994 SWSRRKEEAVVHDDEFDAERIAL------LNELKSLHQDLELLKAEEAVKSLSNNVGVST 2155
S++KEE + E ER +L + E+K+ +LE +K E+ + + V
Sbjct: 10525 --SKQKEEDLTKQKEMKEERKSLEETKARIIEMKT-KAELEDIKKEKEKEEEEEEMRVKV 10581
Query: 2156 KGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHP 2335
+ DG+ D + KS R S + E K D + KI+E
Sbjct: 10582 E------------MDGKELD-RIKSELKRERS--EIDHEQKKLND------DKKIIEQEK 10620
Query: 2336 TEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLK 2515
+K+ K +++ +Q E EL+ K ++ Y K
Sbjct: 10621 QNLEKM--------------------KSEIMKQRQQM-----EEERSELENKIKQTYIEK 10655
Query: 2516 RLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENK---LLPVEEVQRYKMLCVLK 2686
+ N K EI K ++E K EE+ + +
Sbjct: 10656 CDIENSK-------------------EIVQKLMVEVEEQKHEIQFQKEELDIERQKIADE 10696
Query: 2687 EELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDRE 2866
++L + S L+ E+ N + +K + LK+ H +++ +K +++ + +E
Sbjct: 10697 QDLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRL--KE 10754
Query: 2867 IMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEEN 3046
+ + +DV +++ +++ L +E+E +N K L++ +++ D + E++
Sbjct: 10755 DLEKMSTDV-NKQNKDLMNQRD----LLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQD 10809
Query: 3047 -------KEHKRQI------AILEKLKEETENNPGRVFLQSEEREKIEEQKRVL-DQALQ 3184
KE ++ + I K K E E ++EE E+ EE+ RV+ + +
Sbjct: 10810 LPKEKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERK 10869
Query: 3185 ECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDS 3364
E ++K++++ S+ID EQ+KLN ++ + +
Sbjct: 10870 ELYQIKSELERVRSEID---HEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSE 10926
Query: 3365 MQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQ 3544
+ +++ N E K++IEK ++ L+ E EE + + QKE + +E+ ++
Sbjct: 10927 LDNKIQQTNLE-KHDIEKSKEIVEKLMVEVEEQRKDIQL------QKEELDIERQKIADE 10979
Query: 3545 KILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKF 3724
+ LL++ +++ + + E+ + + + +E L++ + L+ ++ +L + ET+
Sbjct: 10980 QNLLVQ-NKAKLQNENERIKKVDEEIKKERETLREMEI----HLKKEKEELRSIIEETQR 11034
Query: 3725 LKEKLLVSDENLKEKDLQLR 3784
KE L ++ E+ L L+
Sbjct: 11035 RKEDLEKMSTDINEQKLHLK 11054
Score = 93.2 bits (230), Expect = 8e-16
Identities = 235/1268 (18%), Positives = 500/1268 (39%), Gaps = 170/1268 (13%)
Frame = +2
Query: 527 VSAQEEEFKEAL--AAKDSENFLLNKKI-EDLNHKIWSLEETLQYKEEVILSSHETISER 697
+ + +E K+ K+ EN L K+I ED KI ++ LQ + E +T +R
Sbjct: 2976 IKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAE------DTEKQR 3029
Query: 698 DRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSL 877
+ KD + ++++ + E + S D + + L + KQ ++T
Sbjct: 3030 RDIEKDRRNNEEMVIKLQNEKKDIETSTDR------IRDEEANLEVQKQRLESDRDTLEK 3083
Query: 878 DCF--RRDEIEDQNIKEEIEKQIVE-TIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDE 1048
+ F + + E N+K+++E QI + I + +IQ+ E + L++ +K +++++ +D
Sbjct: 3084 ERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERD- 3142
Query: 1049 CHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNS 1228
C KE +A+IS LS L+E +++ T ++ D++ + R ++ +K
Sbjct: 3143 CFEKE---KADIS-LSEDLKEQSEREGIDNTRTR------IKQEMDELEKTRQNL-AKEQ 3191
Query: 1229 YIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERG 1408
+ L +I + E +K+++ +KA ++ + K K EL+ ER
Sbjct: 3192 ENNELQKKI--IEDERDKIEQ------------------IKAELKKEAEKTKLELQNERQ 3231
Query: 1409 KISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLE 1588
+ E ++ K ++ LAE + + + +
Sbjct: 3232 NLEEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIELKK 3291
Query: 1589 ELTD----QINIFNSVIDKKE------AEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQS 1738
+TD + ++ N +++++E AE+ D + L+ +S Q+ +I + L+
Sbjct: 3292 TVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQLRL 3351
Query: 1739 FESHIEKL---VNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQE 1909
E +E+L + E+++ ++ + Y L + R N + A
Sbjct: 3352 REVELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREV--NQMMEYASKDR 3409
Query: 1910 QHIEHQCKEEL-EGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSL- 2083
++E + E + + H D+ LN I R + ++ E D +R AL E+K L
Sbjct: 3410 ANLEKEKSEMIAQKHQMDIELNKERGLI---EERTQMLNTYEKEMDQKRTALEVEMKELK 3466
Query: 2084 --------------HQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEA---S 2212
+EL + + +K L + + ++ +++ KD A
Sbjct: 3467 YHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLAHLAE 3526
Query: 2213 DVQGKSRALR-RHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAI---LAFETA 2380
D + K ++ H + A + K S K E +E+KK++ L A
Sbjct: 3527 DTKRKDDEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQQMQA 3586
Query: 2381 DASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXX 2560
+ + K+ ++ + + + ++ EL +++E++ + +L EK L +
Sbjct: 3587 EINRQQTEMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLTEKELLESDRK 3646
Query: 2561 XXXXXXXXXVAE---ITGKFEKVLQENKLLP----------------VEEVQRYKM---- 2671
+ I E + Q+ +LL EE+++ K+
Sbjct: 3647 LLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQH 3706
Query: 2672 -----------LCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLS--DALKKSADHAQRE 2812
+ +E LQ D++ +EI + K + +K D LK + Q+E
Sbjct: 3707 ERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQE 3766
Query: 2813 SH-----LLKHIADLEAGITDREIMTSVCSDVLTALFVEMVR------EKEFSLSLATKE 2959
++K ++L+ ++ + + +D++ + E + E E KE
Sbjct: 3767 LEKEKEIIMKDRSELDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKE 3826
Query: 2960 QETVNQ---------KQMSLRKML--EDKDKLLCLVGEENK-EHKRQIAILEKLKEETEN 3103
+ +Q K M L+K + E+K+KL E+ K E +R+ + K+KEE +N
Sbjct: 3827 KHDFDQGRNSLDEDLKMMKLQKQVFEEEKNKL-----EQMKIELEREAGEIRKIKEEIQN 3881
Query: 3104 NPGRVFLQSEE--REK---------IEEQKRVLDQALQECEELKNDIQNKHSDIDSLRE- 3247
+ +EE REK ++++ +LD+ E L ++Q + S+ + +RE
Sbjct: 3882 ERQSLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMREN 3941
Query: 3248 -------------------------------EQEKLNKQLRCMXXXXXXXXXXXXXXXXX 3334
+Q ++ K+ +
Sbjct: 3942 ISKQTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHK 4001
Query: 3335 XXXISSNLDSMQLELRNYNEE------LKNEIEKKSTDIDLL------------------ 3442
+ + +S++L+ + E +K E+E+++ +I+ +
Sbjct: 4002 IISLDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQI 4061
Query: 3443 IKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSL 3622
KE++++N + T + K+ VL EK + E+KI ++S + ++ + L
Sbjct: 4062 TKERDKINNLIEETNR----KDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSEL 4117
Query: 3623 TEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEK--DLQLRAFEI 3796
+ DL+KQ + E+Q + DLE ++ +E +K+K +L EI
Sbjct: 4118 YKVKEDLEKQKENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEI 4177
Query: 3797 ANSEKQYQ 3820
N +++ +
Sbjct: 4178 QNLQQELE 4185
Score = 91.7 bits (226), Expect = 2e-15
Identities = 261/1407 (18%), Positives = 533/1407 (37%), Gaps = 232/1407 (16%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAET-LERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRN 448
+EVE+ RK ++ + E +ER +I D N L L +N + + E+I+
Sbjct: 10953 VEVEE----QRKDIQLQKEELDIERQKI--ADEQNLLVQNKAKLQNENERIKKVDEEIKK 11006
Query: 449 TKDLLDTVESGLYVSNVVSDAVLNGVVSAQEE------EFKEALAAKDSENFLLNKKIED 610
++ L +E L +++ +E+ + E ++ LL ++ E+
Sbjct: 11007 ERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREE 11066
Query: 611 LNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNE 790
+NH++ L++ + + + E +++++ + K L + +A+ E K + E
Sbjct: 11067 INHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEE----RKSLEETKARIIEMKTKAELQE 11122
Query: 791 MMHMVLEKDNIILSLHKQIELQSQNTQSLDCFR-RDEIEDQNIKEEIEKQIVE------- 946
+M E+D + + ++E + N + R R EI+ + K +K+I+E
Sbjct: 11123 IMQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLE 11182
Query: 947 ---TIYVTQIQELGEE---------------HDL--------------------LRLESA 1012
+ +TQ Q++ EE HD+ +RL+
Sbjct: 11183 KMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKE 11242
Query: 1013 KYQDEIQSLKDEC---------------HAKEMSKQAEISKLSHTLEESIMNSNLESLFT 1147
+ E Q + DE KEM + EI K TL+E + E
Sbjct: 11243 ELDIERQKIADEQGLVVQNKAKLQNENERIKEMDE--EIKKEKETLKEMEAHLRKEKEEM 11300
Query: 1148 AEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXX 1327
+ E T R + + ++ D+ +N L ++ D L E ++ +
Sbjct: 11301 RSVIEETQRRKKEDLEKMSTDVNKQNQ---DLMNQRDLLKQEREEINHKWTQLQQRID-- 11355
Query: 1328 XXXXXTLKASMEMQCSKLKDE-------LEEERGKISENLERISKLQKMNNE---LAERS 1477
+ Q SK K+E +EEER + E +I +++ E+
Sbjct: 11356 ---------EFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKE 11406
Query: 1478 KSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSV---IDKKEAEV 1648
K + + V + ++L D + ++K ++E+
Sbjct: 11407 KEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEI 11466
Query: 1649 SGHLDTISSLQTVLSN-------QKFEIEKSQKVLQSFESHIEKLVND---SLHEVD--- 1789
+ ++ L N ++ +IE S++++Q +E+ D E+D
Sbjct: 11467 MKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIER 11526
Query: 1790 --------------SAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQE--QHIE 1921
+ + N R + ++ ETL+ +++ + + + +
Sbjct: 11527 QKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQ 11586
Query: 1922 HQCKEELEGHIADLVLNDFSNDILSWS---RRKEEAVVHD--------DEFDAERIALLN 2068
+ KE+LE D+ N + D+++ +++ E + H DEFDA+
Sbjct: 11587 RRQKEDLEKMSTDV--NKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQ------ 11638
Query: 2069 ELKSLHQDL-ELLKAEEAVKSLSNN-VGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALR 2242
K +DL + K EE KSL + + + I++ K+ E +V ++
Sbjct: 11639 VSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMK 11698
Query: 2243 RHSTGQA------------FREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADA 2386
+ Q + +D E + +E +E K + E ++
Sbjct: 11699 KEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSEL 11758
Query: 2387 SDSPLRNWPKEQLLGHFKQSFAGL-----KREYELELQRKT-----EEIYDLKRLLLNEK 2536
+ + + ++ + + K+ L ++++E++ Q++ ++I D + LL+ K
Sbjct: 11759 ENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNK 11818
Query: 2537 NGLH------AXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKM--------L 2674
+ L + E+ EK +E K + EE +R K +
Sbjct: 11819 SELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSI-TEETRRQKEDLEKMSTHI 11877
Query: 2675 CVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGI 2854
K++L+S+ D L +E +E + K L +++ + + + Q+E L K E
Sbjct: 11878 NEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSK--QKEEDLPKEKEMKEDRK 11935
Query: 2855 TDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLV 3034
+ E ++ A E+ +EKE +EQE + +M +++ + K +L +
Sbjct: 11936 SLEETKANILEMKTKAEPEEIKKEKEKE----EEEQEMRVKVEMERKEIEQIKSQLERVR 11991
Query: 3035 GEENKEHKR---QIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKN 3205
E + E K+ ++E+ KE+ E + Q R+++EE++ LD+ +++ + K+
Sbjct: 11992 SEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQ---RQQMEEERSELDKKIKQTDLEKH 12048
Query: 3206 DIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXIS------------ 3349
DI+N ++ L E EK +++
Sbjct: 12049 DIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQQNENERIKE 12108
Query: 3350 ---------SNLDSMQLELRNYNEEL----------KNEIEKKSTDI-----------DL 3439
L M++ L+ EE+ K ++EK STDI DL
Sbjct: 12109 MDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDL 12168
Query: 3440 LIKEKEELNERLAYTQKAMEQKEAV----------------------------LVEKLFE 3535
L +E+EE+N +L Q+ +++ E ++E+
Sbjct: 12169 LKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNR 12228
Query: 3536 GEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTE 3715
++ +E QS + E +DLL +E D +K+ EELQ + DLE+ M E
Sbjct: 12229 KRTELEEIEVDQSQQNKNVETMKDLLE---KERKDTEKE----REELQKQADDLEMQMIE 12281
Query: 3716 TKFLKEKLLVSDENLKEKDLQLRAFEI 3796
KE++ + ++K L+ +A EI
Sbjct: 12282 HGD-KEEMSKRSLDEEKKLLEQKANEI 12307
Score = 90.5 bits (223), Expect = 5e-15
Identities = 236/1241 (19%), Positives = 467/1241 (37%), Gaps = 149/1241 (12%)
Frame = +2
Query: 539 EEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISER-DRLLKD 715
+ E ++ + +LN + ++LN +LE+ KEE L S R + LL+D
Sbjct: 12832 QAELQKGQLEMEMHQLMLNSERDELNGMRVNLEKQ---KEEFELMQQNLESRRPESLLED 12888
Query: 716 FIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQ----SLDC 883
+ EK +++ A + ++ N M + + I KQIE + + Q L+
Sbjct: 12889 ILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKI-----KQIEGEIKTKQIEMACLEE 12943
Query: 884 FRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSL-----KDE 1048
++ E+++Q E E Q ++Q EE ++ E +DEIQ L K++
Sbjct: 12944 LKQKELDEQKNMRECENQ--------ELQMRREELAKMKTEIDIERDEIQKLRKQYEKEK 12995
Query: 1049 CHAKEMS---KQAEISKLSHTLEESIMNSNLESL---------FTAEIYENTFRE---LG 1183
C +++ ++ E K+ ++ ++ ++SL A++ +N RE +
Sbjct: 12996 CELEQIKPDLQKREPEKIDAEVQHDEIHGGIDSLKEEREEIEKMKADL-QNKLREAENMR 13054
Query: 1184 DQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTL----- 1348
D + + ++++ K + I+ +A + S+ N LQ++ L
Sbjct: 13055 DIMKREKDELEKKEAEIEQMAVETEDNDSDKN-LQDEMMKIEAILKVTKKQKNYLEQMNE 13113
Query: 1349 -----KASMEMQCSKLKDELEEERGKISENLE-RISKLQKMNNELAERSKSQNSIXXXXX 1510
K +E C L+ E E K+ E E +SK++ ER + +I
Sbjct: 13114 NLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKME-------EREAERKTIERVMD 13166
Query: 1511 XXXXXXXXXXXXXXXVVNMAFGSK-----LEELTDQINIFNSVIDKKEAEVSGHLDTISS 1675
+VNM K LEE +++ S + + +E+ +
Sbjct: 13167 EMAEEHEKIKKEREELVNMEEEIKKQRRVLEESMNEMTKKKSELQHERSELYKQKQQLED 13226
Query: 1676 LQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGE 1855
+ + S K +++ + + I K + + ++ + +++ E
Sbjct: 13227 M--IASESKRDVDTERSRQDKEDEQILKREREEIADMKDQLLKEKEDVETTKERINREKE 13284
Query: 1856 TLRAFVKNIQNQVAVSQEQHIEHQ----CKEELEGHIADLVLNDFSNDILSWSRRKEEAV 2023
+ + +Q +E +E+Q K E++ + L D L R A+
Sbjct: 13285 HIEKMQSQLNDQ---KEEMDLENQKLLYMKTEIQ--VKTNALEKMMQD-LQKERENVNAL 13338
Query: 2024 VHDDEFDAERIALL---NELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEG 2194
V + + E+ +L N+ K H + E+ + E ++S+ + + I + ++
Sbjct: 13339 VIQHQKEREQRDILIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTR 13398
Query: 2195 KDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFE 2374
+ E ++ K + + RE E + E K E EK + +
Sbjct: 13399 SE-ELENLIKKQQKEFETKENEMQRERKALEKMNAEL-ERKSTELKNKIEKVTVWEADLQ 13456
Query: 2375 TADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKT-----EEIYDLKRLLLNEKN 2539
L+N + + +++ ++++E+E RKT E + L+ L +EK
Sbjct: 13457 KEKNKTEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKK 13516
Query: 2540 GLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLL 2719
+ + EI + E + +E K L + + L ++ L
Sbjct: 13517 SMLSRLSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKL 13576
Query: 2720 KEIKEKDSNSKVLA------EKLSDALKKSA--------------DHAQRESHLLKHIAD 2839
+EKDS ++ A EKL + ++K+ D ++E L AD
Sbjct: 13577 SIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRAD 13636
Query: 2840 LEAGI-----------TDREIMTSVCSD---------------------------VLTAL 2905
+E T++EI+ ++ L +
Sbjct: 13637 IERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEKQRKRNDLTLQELRKEKMALEQM 13696
Query: 2906 FVEMVREKEFSLSLATK---EQETVNQKQMSLRKMLEDKDKL-LCLVGEENKEHKRQ--- 3064
++ +EK+ SL + +Q + K+ L + ++ D L + L +N +K+Q
Sbjct: 13697 ITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEV 13756
Query: 3065 -IAILEKLKEETENNPGRVFLQSEERE------KIEEQKRVLD-------QALQECEELK 3202
+ I+E +K + + L E R+ E+QK VL Q E E+
Sbjct: 13757 DVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFT 13816
Query: 3203 NDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELR 3382
DI+ + ++ REE + LNK++ L S+ LE+
Sbjct: 13817 TDIKTEKEHVEKEREEIDVLNKEI---------------------IKSKEELQSLNLEI- 13854
Query: 3383 NYNEELKNEIEKKSTDIDLLIKEKEEL------NERLAYTQKAM------EQKEAVLVEK 3526
E K EI K I+ L + + +L + L T+K M ++ E L
Sbjct: 13855 ---EMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMN 13911
Query: 3527 LFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVA 3706
L + + ++ L ++ A + Q E + +L+ +E D+ S + L+ ++ +L
Sbjct: 13912 LQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKL 13971
Query: 3707 MTETKFLKEKLLVSDENL-----KEKDLQLRAFEIANSEKQ 3814
+ L EK+ E L KE+D +I SEKQ
Sbjct: 13972 ---SHVLNEKVQREQEELERLLEKERDDIENCKKIIESEKQ 14009
Score = 87.8 bits (216), Expect = 3e-14
Identities = 268/1329 (20%), Positives = 516/1329 (38%), Gaps = 159/1329 (11%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNT 451
+EVE+ D R E +ER +I D + L +N + + E+I+
Sbjct: 11506 VEVEEQRKDIRLQKEEL---DIERQKI--ADEQGLVVQNKAKLQNENERIKEMDEEIKKE 11560
Query: 452 KDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENF-------LLNKKIED 610
K+ L +E+ L +V+ Q+E+ ++ + +N LL ++ E+
Sbjct: 11561 KETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREE 11620
Query: 611 LNHKIWSLEETL--------QYKEEVILSSHETISERDRLLKDFI--------------- 721
+NHK L++ + + KEE + + ER L + I
Sbjct: 11621 INHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIK 11680
Query: 722 -----HEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCF 886
E+++M+ + + +++L +++ + E D+ L+ ++ Q + L+
Sbjct: 11681 KEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKM 11740
Query: 887 R-------------RDEIED------------QNIKEEIEKQIVETIYVT-QIQELGEEH 988
+ R E+E+ +N KE ++K +VE +IQ EE
Sbjct: 11741 KSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEEL 11800
Query: 989 DLLRLESAKYQDEIQSLKDEC-HAKEMSKQAE--ISKLSHTLEESIMNSNLESLFTAEIY 1159
D+ R + A QD + K E + E K I K TL+E E I
Sbjct: 11801 DIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSIT 11860
Query: 1160 ENTFRELGD------QISQLRNDMYSKNSYIDS-----------LASRIDFLSSECNKLQ 1288
E T R+ D I++ + D+ S+ ++ L RID ++ +K +
Sbjct: 11861 EETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQK 11920
Query: 1289 EQXXXXXXXXXXXXXXXXTLKAS-MEMQCSKLKDELEEERGKISENLERISKLQKMNNEL 1465
E+ KA+ +EM+ +E+++E+ K E E K++ E+
Sbjct: 11921 EEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEI 11980
Query: 1466 AERSKSQ-----NSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVID 1630
E+ KSQ + + + M S++ + Q+ S +D
Sbjct: 11981 -EQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMK--SEIMKQRQQMEEERSELD 12037
Query: 1631 KK-------EAEVSGHLDTISSLQTVLSNQKFEIEKSQKVL----QSFESHIEKLVNDSL 1777
KK + ++ + + L + QK EI+ ++ L Q + L+ + +
Sbjct: 12038 KKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKI 12097
Query: 1778 HEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIA 1957
+ + N R + ++ ETL+ N+Q + KEE+E I
Sbjct: 12098 EQQNE-----NERIKEMDEEIKKERETLKEMEVNLQKE-------------KEEIESVIE 12139
Query: 1958 DLV-----LNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAV 2122
+ L S DI + +K++ + D ER + ++L L Q ++ +
Sbjct: 12140 ETQRRKEDLEKMSTDI---NEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFET---- 12192
Query: 2123 KSLSNNVGVSTK---GIHYFSQLIQEGKDGEA--SDVQGKSRALRRHSTGQAFREPPKPE 2287
++N+ V+TK +L Q K+ E+ + K L Q+ +
Sbjct: 12193 ---TSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTELEEIEVDQSQQNKNVET 12249
Query: 2288 DLYTTYSEGKIVEPHPTEEKKL---LAILAFETADASDSPLRNWPKEQLLGHFKQSFA-- 2452
E K E E +K L + E D + R+ +E+ L K +
Sbjct: 12250 MKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILR 12309
Query: 2453 ---GLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVL 2623
L++E E ++ +K E+ L++ + N+KN + + E +K L
Sbjct: 12310 QRDDLEKEKE-DMMKKWNELDGLQKEIQNQKNEMEEIKCELETKRIEIIKE-----QKRL 12363
Query: 2624 QENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIK-EKDSNSKVLAEKLSDALKKSADH 2800
+E+ EE Q +++ V E+ Q +I+ + + K E+D +++A+ L D
Sbjct: 12364 EESLNTVNEERQYLEIVRVDYEKHQQQIEEMRVKTKMERDELDQLMAKMLMD-------- 12415
Query: 2801 AQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQK 2980
++E+ K D++ L EM + K F+L +E + QK
Sbjct: 12416 -RKENERSK--------------------DMIGLLKKEMEQTK-FNLDAQEEELKLEKQK 12453
Query: 2981 QMSLRKMLEDKDKLLCLVGEENKEHKRQ-----IAILEKLKEETENNPGRVFLQSE---- 3133
+ +K LE + E K K Q E LKEE + PG+ F+Q +
Sbjct: 12454 IQNEKKDLEMFKAEIKREASEVKTLKEQQLEKDTKAFEALKEE--HLPGQ-FVQQKGGEF 12510
Query: 3134 EREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSL-----REEQEKLNKQLRCMXXXXX 3298
ER +I+E KR+L + +E +EL+ + Q ++L ++ E+L+ L
Sbjct: 12511 ERIQIDEVKRILSEIHKEKKELERNKQILEHQREALLEIKSKQPSERLDVILVSSATQTS 12570
Query: 3299 XXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLA 3478
+ + D ++ + +E + EI+K D +K E + ++A
Sbjct: 12571 DLEDIPDVSASQGETVEKHTDIIKEYTTSIPKE-EYEIDKLKQQGDKKLKSTRE-DTKMA 12628
Query: 3479 YTQKAMEQK---EAVLVEKLFEGE--------------QKILLLESSQSATREQTEKYRD 3607
T+ + K + ++ KL G+ +++ + + + + +++ EK R
Sbjct: 12629 DTEVTTQYKYIPDPSIMMKLESGKDETDGLTEVHTTERRELEITKLALQSEQQEIEKIRQ 12688
Query: 3608 LL----NSLTEEHADLKKQF-------LSATEELQSKERDLEVAMTETKFLKEKLLVSDE 3754
+ N L + +DL+KQ+ + E E DLE + ETK +E+L +
Sbjct: 12689 DIDREKNDLEKYRSDLEKQYEEMEICKQNIENERAELEIDLENIIIETKSKQERLESIEV 12748
Query: 3755 NLKEKDLQL 3781
L+EK++Q+
Sbjct: 12749 QLQEKNVQM 12757
Score = 85.1 bits (209), Expect = 2e-13
Identities = 232/1247 (18%), Positives = 476/1247 (38%), Gaps = 81/1247 (6%)
Frame = +2
Query: 266 SFIEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIR 445
S I+V+ ++ + K + +E+M+ D N L+ D+ + + D++
Sbjct: 279 SAIQVQINEIEMKIGETQKAKDLMEQMKAEIEDEKNELEKKKEDIKRQRDQFEQIKLDLQ 338
Query: 446 NTKDLLD-----TVESGLY------------------VSNVVSDAVLNGVVSAQEEEFKE 556
K ++ T + GL + V + N S QE
Sbjct: 339 QVKMEMEQRWHETEKEGLEQRAVIQREKEQLKYLQDEIQRVREEVERNREFSKQEHARIS 398
Query: 557 ALAAKD-SENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEKD 733
L A+ EN L+ K D+ K LEE K E+ ER R ++ + +
Sbjct: 399 QLRAQALEENNLIENKWHDILRKEKDLEEM---KHEI---------ERGR--EELVMNGE 444
Query: 734 LMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQN 913
L+++ ++ EQ + M+ M D I + ++++ + D + + + +
Sbjct: 445 LVKKEWEKIEQAKVDIQSHMISMEGRVDEIKRETERLKHIKTEMQRDKDALEKQKDDTRK 504
Query: 914 IKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKL 1093
KEE E++ E VT+ E R E + E+Q + D AK + ++ E ++
Sbjct: 505 AKEEAERKRYEI--VTEELEHRARLQRERDELENIRAEMQRVNDVEKAKILKEKEESIRI 562
Query: 1094 SHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSE 1273
EE+ L AEI R Q LR + ++L ++ + +S+
Sbjct: 563 R---EEARQERETTELVNAEIKAEKERLNQRQEEMLRERQEIERIKHETLRAKEEIENSQ 619
Query: 1274 CNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSK-----LKDELEEERGKISENLERIS 1438
++E K E+Q +K K ELEEER E+LER
Sbjct: 620 DVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKEQMEEAKVELEEER----EDLER-- 673
Query: 1439 KLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEEL-TDQINIF 1615
K ++ E+ + +N I V S+ E T+++ +
Sbjct: 674 KRDLVSREIEQAEFLRNEILR-------------------VKEEMESRWRETETEEVEL- 713
Query: 1616 NSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSA 1795
A+ L+ + L+ + IE+S+ L ++ ++KL + +
Sbjct: 714 -------RAKTQHELERLEKLREETERSQKNIEESKIELMLWKESLDKLKGEMEEDKHVV 766
Query: 1796 FCSLNSRFYSLIHKVDNSGETLRAFVKNIQ---NQVAVSQEQHIE-----HQCKEELEGH 1951
+N + E L ++ ++ ++ +S+E+ E ++ + EL+
Sbjct: 767 IMQMN--------EAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQ 818
Query: 1952 IADLVLNDFSNDILSWSRRKEEA-----VVHDDEFDAERIALLNELKSLHQDLELLKAEE 2116
A++ D+ + ++ KEEA VH+ E ++ +E + E L+ +
Sbjct: 819 HAEM--EDWFRVV---NKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRD 873
Query: 2117 AVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLY 2296
++ + + K I Q +++ + E +Q + L + F E + E L
Sbjct: 874 EIQKKAEELEQINKEIQRARQELEKMRYFEKESLQ---KMLEDTQQERVFVEQVRSELLK 930
Query: 2297 TTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYEL 2476
+ K + +E K+L + + D R + E + +QS
Sbjct: 931 NKADQDKCLFEMDSERKELEQMRFQVENEKKDLEQRRY--EMMRYDVEQS---------A 979
Query: 2477 ELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEV 2656
++QR+ EE+ +K L+ + ++ I E+ NK L E
Sbjct: 980 QVQRQKEELEKIKSQLVIDTESMNRSRELARQDREKAELLIVEIQEQREDVNKRLE-ETK 1038
Query: 2657 QRYKMLCVLKEELQSKIDSLLK-------------EIKEKDSNSKVLAEKLSDALKKSAD 2797
QR + L +L+++++++ + L K E+KE+ + + E+L D +K D
Sbjct: 1039 QREEALRLLRKDMENEREDLEKIRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKG-D 1097
Query: 2798 HAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKE---FSLSLATKEQET 2968
+RE + H + E I E M ++ + VE+ ++KE + A E
Sbjct: 1098 QEEREK--INH--EKEEMIRKMEAMKREMGEI-EDMKVELTKQKENIDMKMEHARLEMTN 1152
Query: 2969 VNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKI 3148
+ + L + ED + + E ++ + + K KE+ E ++ L E EK+
Sbjct: 1153 LEMMKADLLRQKEDIENQMLAAKSERQQMEVMRTEILKQKEDVER---KMELAKAEMEKM 1209
Query: 3149 EEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXX 3328
+ K + + +E EE + + +++ ++ E E K+L
Sbjct: 1210 QHVKDEIQKQRKELEERMQKTKREIGEMELMKREMEGKKKELDQRMKLTMRKKEEMERLK 1269
Query: 3329 XXXXXISSNLDSMQLELRNYN---EELKNEIEKKSTDIDLLIKE------KEELNERLAY 3481
+++ ++E E++K EI++ + +L ++E KE++N +
Sbjct: 1270 MEIQRAKDDMEFKRVETERQKYEMEQVKAEIQRAREEFELRVEERDLEEEKEQMNLTIIN 1329
Query: 3482 TQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEK-------------YRDLLNSL 3622
+ +E ++ + F+ E + + SQ T +Q E R++L L
Sbjct: 1330 LIQQIEATREMVHKTKFQFENR---MAGSQMGTADQEEMNAEMQRLILEIEHIREMLRGL 1386
Query: 3623 TEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLK 3763
E K+ EE++ + +++ E ++ +EK++ + L+
Sbjct: 1387 KGEVEQNKEIMKRDREEIRLLKIEVQRRRREIEYREEKIMREQDELE 1433
Score = 84.0 bits (206), Expect = 5e-13
Identities = 228/1214 (18%), Positives = 473/1214 (38%), Gaps = 129/1214 (10%)
Frame = +2
Query: 527 VSAQEEEFKEALAAKDSENFLLNKKIEDLNHK---IWSLEETLQYKE---------EVIL 670
+ ++E+ ++ L A +EN LN++ + L+ K + S + L+YK+ +V
Sbjct: 1591 LQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSEKSKLEYKKPLEIKQVDAQVQT 1650
Query: 671 SSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASR----DNEMMHMVLEKDNIIL--- 829
E SE D L I E D +Q + +Q+L ++ + +M + L +D + L
Sbjct: 1651 ELMEDASEYDMALS--IEELDKQRQFLEYFKQELLAQKCTMERQMAEIELSRDELSLREA 1708
Query: 830 ----------SLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELG 979
+ Q+ELQ Q + +DE+E K E++K V+ TQI E
Sbjct: 1709 TLQTATQTTADMELQLELQKQELEQT----KDEME--RTKLEVQKGWVDL--QTQIAESR 1760
Query: 980 EEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAE-- 1153
E+ +++R+E K +D + ++ + ++ + +A+ L TL + N + +
Sbjct: 1761 EKEEMVRIELEKARDVLNRIRQDVETEKQTMEAD---LKFTLAKEFENLEAQRKMMEDEK 1817
Query: 1154 -IYENTFRELGDQ---ISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXX 1321
EN EL + I + +++M+ + +++ A ++ E K +
Sbjct: 1818 RALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERS 1877
Query: 1322 XXXXXXXTLKASMEMQCSKLK-----------------DELEEERGKISENLERISKLQK 1450
L+ E+ +++K DE+E E+ KI + ++Q
Sbjct: 1878 REIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQT 1937
Query: 1451 -MNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMA-----------------FG 1576
+N + E QN++ V +M
Sbjct: 1938 DLNRQQKEMQDIQNAVFMEKSELKKSQDEIAEQLKQVGDMMQFTQNEKDNLDRERAAIIE 1997
Query: 1577 SKLEELTDQINIFNSVID-----KKEA------------EVSGHLDTISSLQTVLSNQKF 1705
KL+ D ++ N ++ KKE + + + ++ L +K
Sbjct: 1998 QKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKE 2057
Query: 1706 EIE-----------KSQKVLQSFESHIEKLVNDSLHE---VDSAFCSL---NSRFYSLIH 1834
E++ K + VLQ+ EKL D+L E ++ A L ++
Sbjct: 2058 EMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAE 2117
Query: 1835 KVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSN--DILSWSRR 2008
+ E + I+ Q ++ + Q + + + V D N D+ ++
Sbjct: 2118 ETKRKREDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQK 2177
Query: 2009 KEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQ--- 2179
+ + + E +R L+E++ + D E + E L + FS+
Sbjct: 2178 ERQYMDRLVEEIEKRTKALDEMQ-MEVDKERQEVESKRDELEQETSKLREDEDEFSRQKE 2236
Query: 2180 ---LIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKK 2350
+IQ E+ +++ +S + + T F + L +E K + + K
Sbjct: 2237 KNNIIQAEIQKESDNLELQSENISKERT--IFELEKEHLGLRENEAEYKQKQIDELQNKL 2294
Query: 2351 LLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLN 2530
+ + E A R + +++ A ++ E+E R+ E + ++ +N
Sbjct: 2295 RMEKVQVEQMQADKDQQRKKAEYVKTARGRETTALEEQRQEMESLREEYENVEKQKKHVN 2354
Query: 2531 EKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYK-MLCVLKEELQSKI 2707
E+ L + + + EN E +++YK L E+LQ +
Sbjct: 2355 EQKEL-----------------FESRMKSLEMEN-----EAMKKYKEKLDKEYEDLQFQR 2392
Query: 2708 DSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDR-------E 2866
KEI++ + ++ AE + + KK + + + ++ + + + ++ E
Sbjct: 2393 QLFEKEIQQMRTELQIEAENI-ERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDE 2451
Query: 2867 IMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLC--LVGE 3040
+ + +D+ VE + ++L ++E+ +K+ K+ E++ + L +
Sbjct: 2452 VRKKINADLSE---VEKQKSALVQMNLKISQEESYVKKEKDRLKLQENEQNMQMSQLNAK 2508
Query: 3041 ENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNK 3220
+N+ +RQ A +EK K E EN R+ E+EK+E + + Q E++N+++ K
Sbjct: 2509 QNELDERQ-AEMEKQKRELENVMDRL-----EKEKVE-----ITKEKQRVNEMQNEVKRK 2557
Query: 3221 HSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEE- 3397
++ +D ++ QE L +Q I ++ + + EL E+
Sbjct: 2558 NASVDLIK--QEVLREQ----------------------DHIENSREILNRELEKIKEKK 2593
Query: 3398 --LKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAV---LVEKLFEGEQKILLLE 3562
L E E +++ KE + L + A QK E E + E+ ++ L+
Sbjct: 2594 TILAEEFEALDDKKEMIGKEMQRLGKMKAELQKEAEDTEKQRRDIDNDRRNNEEMVIKLQ 2653
Query: 3563 SSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKER-DLEVAMTETKFLKEKL 3739
+ + T++ RD E + ++KQ L + + KER DLE TE K L+++L
Sbjct: 2654 NEKKDIETSTDRIRD-----EEANLRVQKQRLESDRDTLEKERFDLEKTKTEMKDLEKQL 2708
Query: 3740 LVSDENLKEKDLQL 3781
+ ++ ++QL
Sbjct: 2709 ---ESQSRQHEIQL 2719
Score = 83.2 bits (204), Expect = 8e-13
Identities = 212/1227 (17%), Positives = 466/1227 (37%), Gaps = 63/1227 (5%)
Frame = +2
Query: 320 KIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGLYVSNV 499
+I L+ + DT N + +L +D + ++++ +++ + + L +
Sbjct: 7393 QIRAELQNKQRDMDDTTNIMMKEKAELARDLENLQNEKDELQKSRENIQKLMKELQEERL 7452
Query: 500 VSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSH 679
+ LN + ++F E + K N ++++ +I + L +E+I
Sbjct: 7453 KTSEALN----KERQQFTEEIKLK-------NDSLDEIQAEIDRQKRALVTDKEIITKQM 7501
Query: 680 ETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMV--LEKD-NIILSLHKQIE 850
+ + + + E D+ + Q + L E++ LE++ + +L + +E
Sbjct: 7502 MDLQKTQDVRRQS-DESDIARANLQRERESLDQLSVEILKQKQDLERERDELLEQWRLVE 7560
Query: 851 LQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEI 1030
Q + +++ + + ++++ E+I KQ+ + + +L +L L K
Sbjct: 7561 TQKMDNENVKQLKTELLDEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNLQK----- 7615
Query: 1031 QSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRND 1210
Q ++DE +A++ ++ L+ + ++E +YE + ++ +++
Sbjct: 7616 QGIQDE--------RAQLERMKGELQ--MKADDIERKMQEILYEK------QKYAERKSE 7659
Query: 1211 MYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDE 1390
Y +Y+D + + L+ E + E K +E+ ++ + E
Sbjct: 7660 NYKIQTYLDEANAEVQKLNKELERYDENLE----------------KCKLELDKARAETE 7703
Query: 1391 LEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMA 1570
++ KI E + LQK + +
Sbjct: 7704 RVKQGAKIPETQQIEQSLQKERDYI----------------------------------- 7728
Query: 1571 FGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESH 1750
E++ + I+K +AE+ + +Q + QK E+ K QK+ E
Sbjct: 7729 -----EDIRRNLFKKEEAIEKDKAEIRLRHQELDLIQAKVVKQKEEMVK-QKIESEREIQ 7782
Query: 1751 IEKL-VNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQ 1927
EK + S E++ + L D + + R V N QVA +
Sbjct: 7783 QEKKKLQRSEEELEDKMQKIKREMIELKLLQDET-DGKRKDVDNKMRQVA---------R 7832
Query: 1928 CKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLK 2107
++ELE AD+ + S + +++ + + ERI ++ + H
Sbjct: 7833 KRDELEKMKADV-------ESASKKLEVDRVMLNTERDELERIKTESQRATEHMQSH--- 7882
Query: 2108 AEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPE 2287
AEE L V+T+ +LIQE + K R + E
Sbjct: 7883 AEERAGDLGEKEPVNTR----IQRLIQEAEKASKMAWSTKHEPEMRMQREVSVEEESVER 7938
Query: 2288 DLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKRE 2467
+ + I+E E + A S L N E L K++ +
Sbjct: 7939 QDMSANMQRMILEIEHARETLRGMKDEVQAARKERSELENMKLEFLT--MKKNMEKTYEQ 7996
Query: 2468 YELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPV 2647
E+Q++ ++I K LL E+N L + +K+L EN+LL
Sbjct: 7997 QNDEIQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMALDK----QKLLAENELLER 8052
Query: 2648 EEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLK 2827
E+ K++ E L+S + +E A + + A ++ ++ ++ L
Sbjct: 8053 EKADVIKII----ENLESLREEATRE----------RATETAQATRRDSEELMQKMEALS 8098
Query: 2828 HIADLEAGITDREIMTSVCSDVLTALFVEMVREK-EFSLSLATKEQETVNQKQMSLRKML 3004
+ D + ++ + D L L ++++++ E + A +Q+ + ++ +
Sbjct: 8099 -MEDFQEASKNQMVELKRQIDKLIELKADLLQQQTELKKTKADLKQQMDDLEKTRSEILK 8157
Query: 3005 EDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEE----REKIEEQKRVLD 3172
+KD ++K + ++ +++ K++ E ++ L+ + R +I +K+ LD
Sbjct: 8158 HEKDT-------DSKTRELELIEIQRQKDDLETRIQKLTLEKRDLEVLRSEIVLEKKDLD 8210
Query: 3173 QALQ-------ECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXX 3331
Q ++ E E++++DI N +I+ R+E E L ++
Sbjct: 8211 QKMKQVIRKRDEMEKIRSDIANATEEINRERQELEILRNNVQ-SARHDFELLLERTANLE 8269
Query: 3332 XXXXISSNLDSMQLE-------LRNYNEELKNEIEKKSTDIDLLIKEKEELN-------- 3466
+++++ + LE +RN E++ +EK +ID K E+
Sbjct: 8270 DEESAATDIERLVLEVVKIREMVRNLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDIGQ 8329
Query: 3467 ------------ERLAYTQKAMEQKEAVLVEKLFEGE----------QKILLLESSQSAT 3580
E+ ++ +E+ A L EK E E +++ L+ +
Sbjct: 8330 IRENLGGLGEEIEKTRRDKRELEKMRAELAEKQQEQESMREMLHKEREELEQLKDEINRE 8389
Query: 3581 REQTEKYRDLLNSLTE-----EHADL---KKQFLSATEELQSKERDLEVAMTETKFLKEK 3736
+E E R+L+ ++ + E D+ K++ S TEEL +K+RDL+ ++ + L++
Sbjct: 8390 KEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQT 8449
Query: 3737 L--LVSDENLKEKDLQLRAFEIANSEK 3811
+ + K +L+ FE+ E+
Sbjct: 8450 IEEINIQHGKKRAELEGIGFELKKGEQ 8476
Score = 73.9 bits (180), Expect = 5e-10
Identities = 215/1271 (16%), Positives = 497/1271 (39%), Gaps = 103/1271 (8%)
Frame = +2
Query: 296 DTRKSLETKI---AETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLD 466
+ K ++T + A+ +E++++ ++ + ++ + L+E+I+ +D++D
Sbjct: 6736 EAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIKKKRDIID 6795
Query: 467 TVESGLYVSNVVSDAVLNGVVSAQEEEFKE------ALAAKDSENFLLNKKIEDLNHKIW 628
+ + ++ + + A+ + FK+ ALA + L K ++++
Sbjct: 6796 ESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQQKRNALEKMSKEISRDRM 6855
Query: 629 SLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVL 808
LE+ K+E+ L+ E +R+ D QR QE + L S +
Sbjct: 6856 KLEDE---KKEIQLAREEL----ERMHGDM--------QRQQEAKDHLLSG--------I 6892
Query: 809 EKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEH 988
++++ +I LQ R+ EI D + + ++V Q+ E+ +
Sbjct: 6893 TDESLLKKSEAEIVLQPSQVDKAKPARKTEISDSD---------KQPVFVQQMPEM-DLK 6942
Query: 989 DLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESL--FTAEIYE 1162
D L+ + + ++ +KD + K LE+ ++ ++ L AE+ +
Sbjct: 6943 DALKKDFESEKLDLPKVKDVLPQDQQMK----------LEQKLIEDEMDKLKQMRAELQK 6992
Query: 1163 NTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXX 1342
DQI + + DM ++ +D +A+R+ +L E+
Sbjct: 6993 EA-----DQIEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINIQ------------ 7035
Query: 1343 TLKASMEMQCSKLKDELEEERGKISENLERI-SKLQKMNNELAERSKSQNSIXXXXXXXX 1519
K + + Q + + E + ERI +++ + N ELA++ +
Sbjct: 7036 --KVNQQKQATAFQME--------KTDFERIKTEIDQANKELADQQE------------- 7072
Query: 1520 XXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQ 1699
K ++ ++ +++ A +S ++TI++ LS++
Sbjct: 7073 --------------------KNKKTITEMQKERETLEEMRANISKQVETITNENKSLSSR 7112
Query: 1700 KFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYS---LIHKVDNSGETLRAF 1870
+ E+ K Q+ + + +++L N + E+ C L+ R L +VD+ + +
Sbjct: 7113 ESELAKLQEDILQQQQEMDELKNTIMMEM----CQLDQRQSDIDLLQKEVDDLMDFTKTE 7168
Query: 1871 VKNIQNQ--VAVSQEQHIEHQCKE-ELEGHIAD---LVLNDFSNDILSWSRRKEEAVVHD 2032
+ N++ + ++Q ++I+ ++E + L LN+ D++ + +E +
Sbjct: 7169 MANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNE-EKDLIE--KERELLTKNL 7225
Query: 2033 DEFDAERIALLNELKSLHQDLELLKAEEA-VKSLSNNVGVSTKGIHYFSQLIQEGK---- 2197
D D +++ + EL++L + E +K E+ ++ + ++ G FS+ ++ +
Sbjct: 7226 DHTDKDKMDMKRELENLKVEKETIKNEKKELEKMKISLQRKAIGFKEFSEKTKDERPIVE 7285
Query: 2198 ----------DGEASDVQGKSRALRRHSTGQAFREPPKPEDLYT-------------TYS 2308
D +GK R T + R+ EDL+ Y
Sbjct: 7286 EMAAQFTRQLDISERPAEGKFIEERLDQTEKKRRKTYYTEDLFQEEKTDLQKTKEEINYD 7345
Query: 2309 EGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQR 2488
+I K+ + T++ + KE++ + + + ELQ
Sbjct: 7346 REEIYRQRTELNKEKETLKQMHTSNLKEIENIEKEKEKIQRTWNEL-----DQIRAELQN 7400
Query: 2489 KTEEIYDLKRLLLNEKNGL--HAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQR 2662
K ++ D +++ EK L E K K LQE +L E + +
Sbjct: 7401 KQRDMDDTTNIMMKEKAELARDLENLQNEKDELQKSRENIQKLMKELQEERLKTSEALNK 7460
Query: 2663 YKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLA-------------EKLSDALKKSAD-- 2797
+ EE++ K DSL + E D + L +K D ++S +
Sbjct: 7461 ERQQ--FTEEIKLKNDSLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDVRRQSDESD 7518
Query: 2798 ------HAQRES------HLLKHIADLEAGITD-----REIMTS-VCSDVLTALFVEMVR 2923
+RES +LK DLE + R + T + ++ + L E++
Sbjct: 7519 IARANLQRERESLDQLSVEILKQKQDLERERDELLEQWRLVETQKMDNENVKQLKTELLD 7578
Query: 2924 EKEFSLSLATKEQET---VNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEE 3094
EKE + + + ++ + + +++L K LE+ + + +E + +R L+ ++
Sbjct: 7579 EKESTEKIRKQLEQDKAYMEENKLNLHKELEELNLQKQGIQDERAQLERMKGELQMKADD 7638
Query: 3095 TENNPGRVFLQSEE-REKIEEQKRV---LDQALQECEELKNDIQNKHSDIDSLREEQEKL 3262
E + + ++ E+ E ++ LD+A E ++L +++ +++ + E +K
Sbjct: 7639 IERKMQEILYEKQKYAERKSENYKIQTYLDEANAEVQKLNKELERYDENLEKCKLELDKA 7698
Query: 3263 NKQLR-----CMXXXXXXXXXXXXXXXXXXXXISSNL-------DSMQLELRNYNEELKN 3406
+ I NL + + E+R ++EL
Sbjct: 7699 RAETERVKQGAKIPETQQIEQSLQKERDYIEDIRRNLFKKEEAIEKDKAEIRLRHQELDL 7758
Query: 3407 EIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATRE 3586
K + ++K+K E + +K +++ E L +K+ + +++++ L+ Q T
Sbjct: 7759 IQAKVVKQKEEMVKQKIESEREIQQEKKKLQRSEEELEDKMQKIKREMIELKLLQDETDG 7818
Query: 3587 QTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKE 3766
+ + + + + + +L+K + A E SK+ +++ M T+ + + + ++
Sbjct: 7819 KRKDVDNKMRQVARKRDELEK--MKADVESASKKLEVDRVMLNTERDELERIKTESQRAT 7876
Query: 3767 KDLQLRAFEIA 3799
+ +Q A E A
Sbjct: 7877 EHMQSHAEERA 7887
Score = 70.9 bits (172), Expect = 4e-09
Identities = 202/1162 (17%), Positives = 457/1162 (39%), Gaps = 73/1162 (6%)
Frame = +2
Query: 527 VSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVI------------- 667
+ EEF+ + +D L ++ E +N I +L + ++ E++
Sbjct: 1300 IQRAREEFELRVEERD-----LEEEKEQMNLTIINLIQQIEATREMVHKTKFQFENRMAG 1354
Query: 668 -----LSSHETISERDRLLKDFIHEKDLMQQRAQETEQ--KLASRDNEMMHMVLEKDNII 826
E +E RL+ + H +++++ E EQ ++ RD E + ++ + +
Sbjct: 1355 SQMGTADQEEMNAEMQRLILEIEHIREMLRGLKGEVEQNKEIMKRDREEIRLLKIE---V 1411
Query: 827 LSLHKQIELQSQNTQSLDCFRRDEIE-----DQNIKEEIEKQIVETIYVTQIQELGEEHD 991
++IE + + +DE+E Q +EE+E+++ E I +E+D
Sbjct: 1412 QRRRREIEYREEKIMR----EQDELELMSKMGQRQREELEERLEEVI---------KEND 1458
Query: 992 LLRLESAKYQDEIQSLKDECHAKE-MSKQAEISKLSHTLEESIMNSNLESLFTAE----- 1153
R+E + +D +LKD AKE + +Q E+ + + E T E
Sbjct: 1459 --RVEQMR-EDVNNALKDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAIK 1515
Query: 1154 IYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXX 1333
Y + EL I + R ++ I ++ + + ++
Sbjct: 1516 SYRASDLELSASIQKERQELEHYKEIILKEKHELNKIKEDVKAVKNDAEERMIKLHEEEK 1575
Query: 1334 XXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXX 1513
T + S++ +L+ E E+ N + + + N +L ER + +
Sbjct: 1576 EMKTKRVSLQNWERQLQTEKEK-------NQKGLDAIWNENQQLNERKQQLDIKELHLQS 1628
Query: 1514 XXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSV--IDKKEAEVSGHLDTISSLQTV 1687
V+ ++L E + ++ S+ +DK+ + + + +
Sbjct: 1629 EKSKLEYKKPLEIKQVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCT 1688
Query: 1688 LSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRA 1867
+ Q EIE S+ L E+ ++ + L + L D T
Sbjct: 1689 MERQMAEIELSRDELSLREATLQTATQTTA----DMELQLELQKQELEQTKDEMERTKLE 1744
Query: 1868 FVK---NIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHD-- 2032
K ++Q Q+A S+E+ E + ELE A VLN D+ + + E +
Sbjct: 1745 VQKGWVDLQTQIAESREK--EEMVRIELEK--ARDVLNRIRQDVETEKQTMEADLKFTLA 1800
Query: 2033 ---DEFDAERIALLNELKSL-HQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQ---E 2191
+ +A+R + +E ++L + EL + ++ +N+ + + +++ ++ E
Sbjct: 1801 KEFENLEAQRKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWE 1860
Query: 2192 GKDGEASDVQG----KSRALR-----RHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEE 2344
+ + D+Q +SR ++ R + D+ SE + E
Sbjct: 1861 ELEKKRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIEN 1920
Query: 2345 KKLLAILAFETADASDSPLRNWPKEQ--LLGHFKQSFAGLKREYELELQRKTEEIYDLKR 2518
+K + + L KE + + LK+ + E+ + +++ D+ +
Sbjct: 1921 EKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQD-EIAEQLKQVGDMMQ 1979
Query: 2519 LLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQ 2698
NEK+ L ++T + L+ KL+ E + ++L E+ +
Sbjct: 1980 FTQNEKDNLDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLL----EDCR 2035
Query: 2699 SKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDR-EIMT 2875
SL++++++ + K+ E+ + ++ E L+ + A T++ I T
Sbjct: 2036 I---SLMRDMQDLEQ-MKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDT 2091
Query: 2876 SVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEH 3055
L VE+ +E++ +++A E +K+ + K+ +K + +
Sbjct: 2092 LAEKQKLEDAAVELQKERDEIMNIA----EETKRKREDVDKIRVGIEKQEITFKDLKADL 2147
Query: 3056 KRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECE-------ELKNDIQ 3214
+++ AI+E ++ + + V + +I+++++ +D+ ++E E E++ ++
Sbjct: 2148 QKEAAIVENQRQAVQKDIQNV---KDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVD 2204
Query: 3215 NKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNE 3394
+ +++S R+E E+ +LR I D+++L+ N ++
Sbjct: 2205 KERQEVESKRDELEQETSKLR---EDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISK 2261
Query: 3395 EL------KNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILL 3556
E K + + + + K+ +EL +L + +EQ +A ++ +K
Sbjct: 2262 ERTIFELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQ----RKKAEY 2317
Query: 3557 LESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEE---LQSKERDLEVAMTETKFL 3727
+++++ E+ R + SL EE+ +++KQ E+ +S+ + LE+ K
Sbjct: 2318 VKTARGRETTALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKY 2377
Query: 3728 KEKLLVSDENLKEKDLQLRAFE 3793
KEKL D+ ++ Q + FE
Sbjct: 2378 KEKL---DKEYEDLQFQRQLFE 2396
Score = 63.5 bits (153), Expect = 7e-07
Identities = 89/436 (20%), Positives = 190/436 (43%), Gaps = 38/436 (8%)
Frame = +2
Query: 2588 VAEITGKFEKVLQENKLLPVEEVQRYKMLCVLK----EELQSKIDSLLKE--------IK 2731
V ++ +QE + + +E+V R K + ++ E+ +S I ++E +K
Sbjct: 14511 VTKLEDTLTSEVQEMRDMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEETLK 14570
Query: 2732 EKDSNSKVLAEKLSDA--LKKSADHAQRESHLL-----KHIADLEAGIT----DREIMTS 2878
EK N + L + L D L + D +E + ++IA LE I D+E +
Sbjct: 14571 EKSRNEETLLQLLHDKDDLSNTLDEKSKEIENITVTFKRNIAQLETTIAMMKKDKE---N 14627
Query: 2879 VCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHK 3058
+ +++L E RE + + E+E ++K ++ + LED +E K+
Sbjct: 14628 IENELLQLKQTEQEREIQRGTDDTSNERENYDEK-VTYKTELEDS--------KEKKKPD 14678
Query: 3059 RQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHS---D 3229
R + L+ ++ G Q+ E K+++ ++ D Q+ EEL ++++NK +
Sbjct: 14679 RDSS-LKLTDADSAKTDGEREAQTLET-KVQDVLQLTDYTTQDQEELHDEMENKMKIILE 14736
Query: 3230 IDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNE----- 3394
++ +++ +KL ++ R + S + S+ E+ + +
Sbjct: 14737 LNEAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEM 14796
Query: 3395 ---ELKNEIEKKST----DIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKIL 3553
E+K +I+ +S + D+ I++ +E E + K E++ + K + +
Sbjct: 14797 QQIEIKMQIQTRSVATQWETDVQIQQGQEATETTGHITKKSEEEISAKKTK----QPTVT 14852
Query: 3554 LLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKE 3733
LE + ++ + ++ RD LN E+ A +K ++L+ + D++ M E + E
Sbjct: 14853 KLEDTLTS---EVQEMRDSLNKEMEDVARMKTIMKMEKDQLEQAKSDIQTQMEEFERNME 14909
Query: 3734 KLLVSDENLKEKDLQL 3781
+ + +EK LQL
Sbjct: 14910 EAMEEKSRNEEKLLQL 14925
>ref|XP_005159739.1| PREDICTED: titin isoform X2 [Danio rerio]
Length = 15734
Score = 136 bits (343), Expect = 6e-29
Identities = 241/1198 (20%), Positives = 484/1198 (40%), Gaps = 108/1198 (9%)
Frame = +2
Query: 539 EEEFKEALAAKD---SENFLLNKKIEDLNHKIWSLE---ETLQYKEEVILSSHETISERD 700
E + KE L K+ S+ LL K +E+L K+ +E E+L+ E++ + E + +
Sbjct: 3628 EIQMKEVLTEKELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMK 3687
Query: 701 RLLKDFIHEKDLM----QQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNT 868
L+ E + + Q Q E+ A + ++ DNI +H + Q
Sbjct: 3688 TDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMK 3747
Query: 869 QSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDE 1048
Q D + + E QN+++E+EK+ + I + EL + L + D I+++K+E
Sbjct: 3748 QKQDELDQLKTEIQNLQQELEKE--KEIIMKDRSELDLKQSELDKQQTNMNDIIETMKNE 3805
Query: 1049 CHAKEMSKQA------EISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRND 1210
+ K+ EI K H ++ NS E L ++ + F E +++ Q++ +
Sbjct: 3806 RKQLDKDKEEMEEQKREIEKEKHDFDQG-RNSLDEDLKMMKLQKQVFEEEKNKLEQMKIE 3864
Query: 1211 MYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDE 1390
L E +++ K+K+E
Sbjct: 3865 -----------------LEREAGEIR-----------------------------KIKEE 3878
Query: 1391 LEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMA 1570
++ ER + + E + + ++ LAE +K + I
Sbjct: 3879 IQNERQSLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEK------ 3932
Query: 1571 FGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESH 1750
S EE+ + I+ + K+ + D + LQ + Q+ EIEK + ++S +
Sbjct: 3933 --SNFEEMRENISKQTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAA 3990
Query: 1751 IEKLVNDSLHEVDSAFCSLNSRFYSL---IHKVDNSGETLRAFVKNIQNQV----AVSQE 1909
I K+V D H++ SL+ SL +N E L+ ++ + + E
Sbjct: 3991 IIKIVEDLQHKI----ISLDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLE 4046
Query: 1910 QHIEHQCKEELEGHIA----------------DLVLNDFSNDILS--WSRRKEEAVVHDD 2035
+ Q EE+ I D+VLN+ + DI S + ++ ++ +
Sbjct: 4047 TQHDRQRVEEMTAQITKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKE 4106
Query: 2036 EFDAERIALLNELKSLHQDL---------ELLKAEEAVKSLSNNVGVSTKGIHYFSQLI- 2185
+ + E+ +EL + +DL E+ K E ++ ++ N+ + I + + +
Sbjct: 4107 KHNLEKTR--SELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQMK 4164
Query: 2186 --QEGKDGEASDVQGKSRALRRHS-------------TGQAFREPPKPEDLYTTY-SEGK 2317
Q+ D +++Q + L + + ++ D+ T +E K
Sbjct: 4165 QKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNERK 4224
Query: 2318 IVEPHPTEEKKLLAILAFETADASDSPLRNWPKE-QLLGHFKQSFAGLKREYE---LELQ 2485
+++ E ++ + E D D +++ ++ +++ KQ K + E ELQ
Sbjct: 4225 LLDKDKEEMEEQKQEMEKE-RDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQ 4283
Query: 2486 RKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXV--AEITGKFEKVLQENKLL---PVE 2650
R+ +EI +K NE+ L V AE T + +++L E ++ +
Sbjct: 4284 READEIRKIKEETQNERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMA 4343
Query: 2651 EVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKH 2830
++QR K + EE++ I ++I+ + SK+ ++L L+ Q E + K
Sbjct: 4344 DLQREKRIL---EEMRENISKQTEDIENEKEKSKLREDELK-KLQTEVQKQQSEIDMEKT 4399
Query: 2831 IADLEAGITDRE---IMTSV--CSDVLTALFVEMVREKEF---SLSLATKEQETVNQKQM 2986
+ E + RE +MT + S+ + E++ EKE +L K+ E + QK M
Sbjct: 4400 NIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLM 4459
Query: 2987 SLRKMLEDKDKLLCLVGEEN---KEHKRQIAI----LEKLKEETENNPGRVFLQSEEREK 3145
S+ + E G E K+ K + I +EK+K ET+++ RV E+ +
Sbjct: 4460 SIERDSESLKLDREAFGNEKEVLKQMKTDLQIQADEIEKIKLETQHDRQRV---EEKTAQ 4516
Query: 3146 IEEQKRVLDQALQE-------CEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXX 3304
I++ + ++ + E E+ DI+ K I S++ +++ L K+
Sbjct: 4517 IQKDRDEINNLIVETNRKDMVLNEMDRDIEEK---IKSIQSDKDMLEKE----------- 4562
Query: 3305 XXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYT 3484
NL+ + EL E L+ + E + DI+ + K + +
Sbjct: 4563 --------------RHNLEKTRSELARAKENLETQREIERKDIEKMKKNISREMHEIKHQ 4608
Query: 3485 QKAMEQKEAVL---------VEKLFEGEQKILLLESSQSATRE-QTEKYRDLLNSLTEEH 3634
++ M+QK+ L +++ E E++I++ SQ R+ + +K + +N + E
Sbjct: 4609 EEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETM 4668
Query: 3635 ADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSE 3808
+ +KQ EE + +++++E + ++ L DE+LK LQ + E S+
Sbjct: 4669 KNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSL---DEDLKMMKLQKQVIEEEKSK 4723
Score = 122 bits (307), Expect = 9e-25
Identities = 261/1290 (20%), Positives = 533/1290 (41%), Gaps = 129/1290 (10%)
Frame = +2
Query: 296 DTRKSLETKIAETLERMEIH----EGDTANTLK---NMNFDLGQDNPGVPGLLEDIRNTK 454
D K L+T++ + ++++ E + A ++ NM +L + + V +++I K
Sbjct: 5655 DELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEIQMKEILTEK 5714
Query: 455 DLLDTVESGLY--VSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIW 628
+LL L V N+ + + + K A ++E + + DL +
Sbjct: 5715 ELLHNDRKLLTRDVENLQQKLI---DLERDSKRLKLDREAFENEKEAMKQMKTDLQIQAD 5771
Query: 629 SLE----ETLQYKEEVILSSHETISERDRL--LKDFIHEKDL-MQQRAQETEQKLASRDN 787
+E ET ++ V + + ERD++ L + + KD+ + ++ ++ E+K+ S +
Sbjct: 5772 EIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQS 5831
Query: 788 EMMHMVLEKDNI------ILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVET 949
+ + E+ N+ + + + +E Q +NT + R+++E N E I +++ E
Sbjct: 5832 DKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKMN--ENITREMHEI 5889
Query: 950 IYVT-QIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMS----KQAEISKLSHTLEES 1114
+ Q+ + +E D L+ E Q E++ K E K+ S +Q+E+ K +++
Sbjct: 5890 KHQEEQMNQKQDELDQLKTEIQNLQQELEKEK-EIIMKDRSQFDLRQSELDK-----QQT 5943
Query: 1115 IMNSNLESLFTAEIYENTFRELG---DQISQLRNDMYSKNSYIDSLASRIDFLSSECNKL 1285
MN +E++ +N ++L +++ + + +M + D +D + KL
Sbjct: 5944 NMNDIMETM------KNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLD-KDLKMMKL 5996
Query: 1286 QEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNEL 1465
Q+Q +A + K+K+E + ER + + E + K ++ L
Sbjct: 5997 QKQVFEEEKNKLEQMKIELEREAD---EIRKIKEETQNERQSLEKMTEELKKEKESFTHL 6053
Query: 1466 AERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAE 1645
AE +K + I S LEE+ + I+ ++ K+
Sbjct: 6054 AEDTKKEQEILDKVKVANESLMADLQKEK--------SNLEEMRENISKQTEDVENKKEN 6105
Query: 1646 VSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEV-----DSAFCSLN 1810
+ D + LQ + Q+ EIEK + ++S + I K V D H++ DS L+
Sbjct: 6106 LRLREDELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLD 6165
Query: 1811 SRFYSLIHKVDNSGETLRAFVKNIQNQV----AVSQEQHIEHQCKEELEGHIADLVLNDF 1978
+ +N E L+ ++ + + E + Q EE+ I D
Sbjct: 6166 REAF------ENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQK--DRDK 6217
Query: 1979 SNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTK 2158
N+++ + RK + V+++ D E+ ++KS+ D ++L+ E+ +++ +
Sbjct: 6218 INNLIEETNRK-DMVLNEKNRDIEK-----KIKSIQSDKDMLEKEK------HDLEKTRS 6265
Query: 2159 GIHYFSQLIQEGKDGEASDVQGKSRALRRHSTG----------QAFREPPKPEDLYTTYS 2308
++ + +++ K+ + +Q + L + + Q + K ++L +
Sbjct: 6266 ELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKT 6325
Query: 2309 EGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQR 2488
E + ++ +EK+++ + A D S L K+Q + +K E + +L +
Sbjct: 6326 EIQNLQQELEKEKEII-MKARSQLDRRQSEL---DKQQT--NMNDIMETMKNERK-QLDK 6378
Query: 2489 KTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYK 2668
EE+ + K+ + E++ + K+++ K + EE + +
Sbjct: 6379 DKEEMEEQKQEMEKERDNMDQSRKSLDEDL------------KMMKLQKQVIEEEKNKLE 6426
Query: 2669 MLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKS-------ADHAQRESHLL- 2824
+K EL+ + D +++IKE+ N + + EK+++ LKK A+ +RE + L
Sbjct: 6427 Q---MKIELEREADD-IRKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTKREKNSLD 6482
Query: 2825 -------KHIADLEAGITDREIMTSVCSDVLTALFVE----MVREKEF---------SLS 2944
+ADL+ ++ E M S + E +RE E S
Sbjct: 6483 EMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQS 6542
Query: 2945 LATKEQETVNQKQMSLRKMLED-KDKLLCL------------VGEENKEHKRQIAI---- 3073
E+ + +++ ++ K +ED + K++ L E KE +Q+
Sbjct: 6543 ETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELER 6602
Query: 3074 ----LEKLKEETENNPGRV------FLQ--SEEREKIEEQKRVLDQALQECEELKNDIQN 3217
+EK+K ET++ RV F++ + ER+++++ K ++++ QE E+ ++D+
Sbjct: 6603 EADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQ 6662
Query: 3218 KHSDIDS-----------LREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDS 3364
+D L EE+ KL + M NL+
Sbjct: 6663 SRKSLDEDLKMMKAQKQVLEEEKNKLEQ----MKIGLEREADEISKIKEETQNERQNLEK 6718
Query: 3365 MQLELRNYNEELKNEIEKKSTDIDL-----------LIKEKEELNERLAYTQKAMEQKEA 3511
M L+ E L EI++K+ +D L KEK L E K +E E
Sbjct: 6719 MANALKEEREYLAEEIKRKNQVLDKIKVANESTLADLQKEKRILEEMRENISKQIEDIEN 6778
Query: 3512 VLVE-KLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKE 3688
+ KL E E K L E + + EK ++ E A + ++ + EL+ K
Sbjct: 6779 EKEKSKLREDELKKLQTEVQKQQSEIDMEK-----TNIESERAAMIREKQNMMTELKKKS 6833
Query: 3689 RDLEVAMTETKFLKEKLLVSDENLKEKDLQ 3778
D+E+ M E KE LL +D NL +KD++
Sbjct: 6834 EDVEMQMKEILTEKE-LLHNDRNLLKKDVE 6862
Score = 121 bits (303), Expect = 3e-24
Identities = 240/1245 (19%), Positives = 507/1245 (40%), Gaps = 81/1245 (6%)
Frame = +2
Query: 329 ETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGLYVSNVVSD 508
+ L+ M++ T + +L + + ED+ N K+ + E L
Sbjct: 4775 QVLDEMKVANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLREEKL-------- 4826
Query: 509 AVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLE---ETLQY--------K 655
L + Q+ E ++ + + E + K +EDL KI SL+ E+L+ K
Sbjct: 4827 KQLQAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEK 4886
Query: 656 EEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRD--NEMMHMVLEKDNIIL 829
EE+ E E D + K + + Q+ + T Q RD N ++ KD ++
Sbjct: 4887 EELKQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQKERDKINNLIEETNRKDMVLN 4946
Query: 830 SLHKQIELQSQNTQSLDCFRRDEIEDQN------------IKEEIEKQIVETIYVTQIQE 973
+ +I+ + + +S RD +E + KE +EKQ I + +IQ+
Sbjct: 4947 EIKTEIKEKIKAIES----DRDMLEKEKHDLEKTRSKLLRAKENLEKQ--RKIKLAEIQK 5000
Query: 974 LGEE------------HDLLRLESA--KYQDEIQSLKDECH--AKEMSKQAEISKLSHTL 1105
E+ HD+ E + QDE+ LK E +E+ K+ EI +
Sbjct: 5001 EREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRS- 5059
Query: 1106 EESIMNSNLESLFT-----AEIYENTFRELG---DQISQLRNDMYSKNSYIDSLASRIDF 1261
+ + S L+ T E +N ++L ++ + + +M + D +D
Sbjct: 5060 QLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDE 5119
Query: 1262 LSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISK 1441
+ KLQ+Q +A ++ K+K+E++ ER +NLE++++
Sbjct: 5120 -DLKMMKLQKQVLEDEKSKLEQMKIELEREA---VEIRKIKEEIQNER----QNLEKMTE 5171
Query: 1442 -LQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFN 1618
L++ +LAE +K N + S LEE+ + I+
Sbjct: 5172 ALKEEREDLAEETKKNNQVLDEMKVANESTLADILREK--------SNLEEMRENISKQT 5223
Query: 1619 SVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEV---- 1786
++ K+ + D + LQ + Q+ EIEK + ++S + I K V D H++
Sbjct: 5224 EDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLD 5283
Query: 1787 -DSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADL 1963
D+ L+ + +N E L+ ++ + ++ +E Q + +A
Sbjct: 5284 RDAESLKLDREAF------ENEKEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQ 5337
Query: 1964 VLNDFS--NDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSN 2137
+ D N+++ + RK+ V+++ D E ++KS+ D ++L+ E+ +
Sbjct: 5338 IQKDRDEINNLIEETNRKD-MVLNEKNRDIEE-----KIKSIQSDKDMLEKEK------H 5385
Query: 2138 NVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTG----------QAFREPPKPE 2287
++ + ++ + +++ K+ +++Q + L + + Q + K +
Sbjct: 5386 DLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQD 5445
Query: 2288 DLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKRE 2467
+L +E + ++ +EK+++ D S LR ++ + +K E
Sbjct: 5446 ELDQLKTEIQNLQQELEKEKEIIM------KDRSQLDLRQSELDKQQTNMNDIMETMKNE 5499
Query: 2468 YELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPV 2647
+ +L + EE+ + K+ + E++ + + + +K ++ K +
Sbjct: 5500 RK-QLDKDKEEMEEQKQEMEKERDNMDQSR------------KSLDEDQKKMKLQKQMFE 5546
Query: 2648 EEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDAL---KKSADHAQRESH 2818
EE + + + K EL+ + D + K IKE+ N + EK+++ L K+S H ++
Sbjct: 5547 EEKNKLEQM---KIELEREADEISK-IKEETQNKRQRLEKMTEELIREKESLAHLAEDTK 5602
Query: 2819 LLKHIADLEAGITDREIMTSVCSD--VLTALFVEMVREKEFSLSLATKEQETVNQKQMSL 2992
K I D E + + M + + +L + + + KE+ E+E ++ L
Sbjct: 5603 TEKKILD-EMKVANESSMADLQREKSILEEMRENISKLKEY----IDNEKEKSKLREDEL 5657
Query: 2993 RKMLEDKDKLLCLVGEE--NKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRV 3166
+K+ + K + E N E +R I EK + +E ++K E+ +
Sbjct: 5658 KKLQTEVQKQQSKIDMEKTNIESERAAMIREKQN-----------MMTELKKKSEDVEIQ 5706
Query: 3167 LDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXI 3346
+ + L E E L ND + D+++L+++ L + + + +
Sbjct: 5707 MKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDL 5766
Query: 3347 SSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEK 3526
D ++ +++ + + +E+ + I KE++++N + T + K+ VL EK
Sbjct: 5767 QIQADEIE-KIKLETQHDRQRVEEMAAQIQ---KERDKINNLIEETNR----KDMVLNEK 5818
Query: 3527 LFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEV- 3703
+ E+KI ++S + ++ + L + DL+KQ + E+Q + D+E
Sbjct: 5819 NRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKM 5878
Query: 3704 ------AMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQYQ 3820
M E K +E++ N K+ +L EI N +++ +
Sbjct: 5879 NENITREMHEIKHQEEQM-----NQKQDELDQLKTEIQNLQQELE 5918
Score = 115 bits (289), Expect = 1e-22
Identities = 237/1298 (18%), Positives = 507/1298 (39%), Gaps = 114/1298 (8%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNT 451
IE + L + L E L++M+ A ++ + + + V + I+
Sbjct: 3662 IESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKD 3721
Query: 452 KDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWS 631
++ L + ++ + D + QE++ K+ +++ L +I +
Sbjct: 3722 REYLQKMNDN--ITREIHD------IKYQEKQMKQK-----------QDELDQLKTEIQN 3762
Query: 632 LEETLQYKEEVILSSHETI----SERDRL---LKDFIH---------EKDLMQQRAQETE 763
L++ L+ ++E+I+ + SE D+ + D I +KD + Q+ E
Sbjct: 3763 LQQELEKEKEIIMKDRSELDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKRE 3822
Query: 764 QKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNT--QSLDCFRRDEIEDQNIKEEIEKQ 937
+ D + L++D ++ L KQ+ + +N Q R+ E + IKEEI+ +
Sbjct: 3823 IEKEKHDFDQGRNSLDEDLKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNE 3882
Query: 938 IVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESI 1117
+T+ + +E E K + EI DE S AE+ K EE
Sbjct: 3883 RQSLEKMTEELKREKESFTHLAEDTKKEQEIL---DEIKVANESLMAELQKEKSNFEEMR 3939
Query: 1118 MNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQX 1297
N + ++ EN R D++ QL+ +++ + I+ S I+ + K+ E
Sbjct: 3940 ENISKQTEDVKNKKEN-LRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDL 3998
Query: 1298 XXXXXXXXXXXXXXXTLKASMEMQ---CSKLKDELEEERGKISE-NLERISKLQKMNNEL 1465
+ + E + ++K ELE E +I + LE Q++
Sbjct: 3999 QHKIISLDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMT 4058
Query: 1466 AERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAE 1645
A+ +K ++ K+ L ++ N + V+++K +
Sbjct: 4059 AQITKERD------------------------------KINNLIEETNRKDMVLNEKNRD 4088
Query: 1646 VSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSA---FCSLNSR 1816
+ + +I S + +L +K +EK++ L + +EK ++L E+ +N
Sbjct: 4089 IEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNEN 4148
Query: 1817 FYSLIHKVDNSGET----------LRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADL- 1963
+H++ + E L+ ++N+Q ++ +E+ I + + EL+ ++L
Sbjct: 4149 ITIEMHEIKHQEEQMKQKQDELDQLKTEIQNLQQEL--EKEKEIIMKDRSELDLRQSELD 4206
Query: 1964 --------VLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAE-- 2113
++ N+ + KEE E + ER + +KSL +DL+++K +
Sbjct: 4207 KQQTNMNDIIETMKNERKLLDKDKEEMEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQ 4266
Query: 2114 --EAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRR------HSTGQAFR 2269
E K+ + + + I+E E ++ ++AL + H R
Sbjct: 4267 VIEEEKNKLEQMKFELQREADEIRKIKEETQNERQSLEKMTKALIKEREDLVHLAEYTKR 4326
Query: 2270 EPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSF 2449
E +++ K EK++L + + ++ K +L +
Sbjct: 4327 EKEMLDEMQVA---NKSSMADLQREKRILEEMRENISKQTEDIENEKEKSKLREDELKKL 4383
Query: 2450 AGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQE 2629
++ + E+ + I + +++ EK + + EI + E + +
Sbjct: 4384 QTEVQKQQSEIDMEKTNIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEKELLEND 4443
Query: 2630 NKLLPVE-EVQRYKMLCVLKEELQSKID--------SLLKEIK-----EKDSNSKVLAEK 2767
+ LL + E + K++ + ++ K+D +LK++K + D K+ E
Sbjct: 4444 SNLLKKDMEDLKQKLMSIERDSESLKLDREAFGNEKEVLKQMKTDLQIQADEIEKIKLET 4503
Query: 2768 LSDA--LKKSADHAQRESHLLKHIA------DLEAGITDREIMTSVCSDVLTALFVEMVR 2923
D +++ Q++ + ++ D+ DR+I + S +E R
Sbjct: 4504 QHDRQRVEEKTAQIQKDRDEINNLIVETNRKDMVLNEMDRDIEEKIKSIQSDKDMLEKER 4563
Query: 2924 ---EKEFS-LSLATKEQETVNQ-KQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLK 3088
EK S L+ A + ET + ++ + KM ++ + + + + ++ K++ L++LK
Sbjct: 4564 HNLEKTRSELARAKENLETQREIERKDIEKMKKNISREMHEIKHQEEQMKQKQDELDQLK 4623
Query: 3089 EETENNP--------------GRVFLQSEEREK-----------IEEQKRVLDQALQECE 3193
E +N ++ L+ E +K ++ +++ LD+ +E E
Sbjct: 4624 TEIQNLQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETE 4683
Query: 3194 ELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQL 3373
E K +++ + D D R+ L++ L+ M + D
Sbjct: 4684 EQKQEMEKEKHDFDQSRKS---LDEDLKMMKLQKQVIEEEKSKLKQMKIELEREAD---- 4736
Query: 3374 ELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQ----KEAVLVEKLFEGE 3541
E+R EE +NE + + L KE+E+L+E + +++ E+ L + L E
Sbjct: 4737 EIRKVKEETQNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRERS 4796
Query: 3542 QKILLLESSQSATRE---QTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMT 3712
+ E+ T + + EK R L + A++ KQ +E + ER+ +
Sbjct: 4797 NLQEMRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNIERERAAIIK 4856
Query: 3713 ETKFLKEKLLVSDENLKEKDLQLRAFEIANSE-KQYQT 3823
+ + L+ K++ D + + L AFE E KQ +T
Sbjct: 4857 DVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKT 4894
Score = 115 bits (287), Expect = 2e-22
Identities = 245/1253 (19%), Positives = 499/1253 (39%), Gaps = 71/1253 (5%)
Frame = +2
Query: 275 EVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTK 454
E ED +T+K+ + L+ M++ T + +L + + ED+ N K
Sbjct: 5176 EREDLAEETKKN-----NQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKK 5230
Query: 455 DLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSL 634
+ L E L L + Q+ E ++ +SE + K +EDL HKI L
Sbjct: 5231 ENLRLREDEL--------RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICL 5282
Query: 635 E---ETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMV 805
+ E+L+ E + E + + L+ E + ++ Q Q++ E M
Sbjct: 5283 DRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIKLETQHDRQRV-----EEMAAQ 5337
Query: 806 LEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEE 985
++KD ++ IE ++ L+ RD IE++ + +K ++E E+
Sbjct: 5338 IQKDRD--EINNLIEETNRKDMVLNEKNRD-IEEKIKSIQSDKDMLEK----------EK 5384
Query: 986 HDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYEN 1165
HDL K + E+ +K++ ++ + AEI K LE+ MN N+ T E++E
Sbjct: 5385 HDL-----EKTRSELYKVKEDLEKQKENTLAEIQKEREDLEK--MNENI----TREMHEI 5433
Query: 1166 TFRE------------LGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXX 1309
+E L +I L+ ++ + I S++D SE +K Q
Sbjct: 5434 KHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIM 5493
Query: 1310 XXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISEN---LERISKLQKMNNELAERSK 1480
K ME Q K E+E+ER + ++ L+ K K+ ++ E K
Sbjct: 5494 ETMKNERKQLDKDKEEMEEQ----KQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEK 5549
Query: 1481 SQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHL 1660
N + N +LE++T+++ +E E HL
Sbjct: 5550 --NKLEQMKIELEREADEISKIKEETQNKR--QRLEKMTEELI--------REKESLAHL 5597
Query: 1661 -DTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHK 1837
+ + + +L K E S LQ +S +E++ L
Sbjct: 5598 AEDTKTEKKILDEMKVANESSMADLQREKSILEEM---------------RENISKLKEY 5642
Query: 1838 VDNSGETLRAFVKNIQN-QVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKE 2014
+DN E + ++ Q V ++Q K +E A ++ + N + ++ E
Sbjct: 5643 IDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMI-REKQNMMTELKKKSE 5701
Query: 2015 EAVVHDDEFDAERIALLNELKSLHQDLELLKAEEA-VKSLSNNVGVSTKGIHYFSQLIQE 2191
+ + E E+ L N+ K L +D+E L+ + ++ S + + + + +++
Sbjct: 5702 DVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQ 5761
Query: 2192 GKDG---EASDVQGKSRALRRHS-------TGQAFREPPKPEDLYTTYSEGKIV--EPHP 2335
K +A +++ K + +H Q +E K +L + +V E +
Sbjct: 5762 MKTDLQIQADEIE-KIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNR 5820
Query: 2336 TEEKKLLAILAFETADASDSPLRNWPKEQL-LGHFKQSFAGLKREYELELQRKTEEIYDL 2512
E+K+ +I + + D + N K + L K+ K E+Q++ E++ +
Sbjct: 5821 DIEEKIKSIQSDK--DMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKM 5878
Query: 2513 KRLLLNEKNGL---HAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQ---RYKML 2674
+ E + + EI +++ +E +++ + Q R L
Sbjct: 5879 NENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQFDLRQSEL 5938
Query: 2675 CVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGI 2854
+ + ++++ E K+ D + + + E+ + K+ D Q L K DL+
Sbjct: 5939 DKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDK---DLKMMK 5995
Query: 2855 TDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLV 3034
+++ + L + +E+ RE + + ++ET N++Q SL KM E+ K
Sbjct: 5996 LQKQVFEEE-KNKLEQMKIELEREAD---EIRKIKEETQNERQ-SLEKMTEELKKEKESF 6050
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQ 3214
++ K++ IL+K+K E+ + +E+ +EE + + + ++ E K +++
Sbjct: 6051 THLAEDTKKEQEILDKVKVANESLMADL---QKEKSNLEEMRENISKQTEDVENKKENLR 6107
Query: 3215 NKHSDIDSLREEQEKLNKQLRC--MXXXXXXXXXXXXXXXXXXXXISSNLDSMQLEL--- 3379
+ ++ L+ E K +++ + IS + DS L+L
Sbjct: 6108 LREDELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDRE 6167
Query: 3380 -----RNYNEELKNEIEKKSTDIDLLIKE----KEELNERLAYTQKAME----------Q 3502
R +++K E+E+++ +I+ + E ++ + E A QK + +
Sbjct: 6168 AFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNR 6227
Query: 3503 KEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQS 3682
K+ VL EK + E+KI ++S + ++ + L + DL+KQ + ++Q
Sbjct: 6228 KDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQK 6287
Query: 3683 KERDLEV-------AMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQYQ 3820
+ DLE M E K +E++ N K+ +L EI N +++ +
Sbjct: 6288 EREDLEKMNENITREMHEIKHQEEQM-----NQKQDELDQLKTEIQNLQQELE 6335
Score = 114 bits (285), Expect = 3e-22
Identities = 238/1256 (18%), Positives = 500/1256 (39%), Gaps = 82/1256 (6%)
Frame = +2
Query: 287 GGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLD 466
GGL T + LE+M+ + ++M L ++ + L +DI K+ D
Sbjct: 8852 GGLKTEIENTKRDKSNLEKMKAELEEKQQEEESMREILQKEKEELEQLKKDINREKE--D 8909
Query: 467 TVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETL 646
S V + + + + G Q+ +KE L E + +E LN + L +TL
Sbjct: 8910 IEISRELVESEIYEGEVKGFTDVQK--YKEELQIVTEELLTKKRNLEQLNSDVQHLMQTL 8967
Query: 647 QYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQK-LASRDNEMMHMVLEKDNI 823
EEV + + +E + + + + +++++ ++ E+ + EMM + LE N+
Sbjct: 8968 ---EEVDIQYIKKKAELEHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINM 9024
Query: 824 -ILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLR 1000
IL + +E + +N RR++ E + + E+++Q E + Q L E D +
Sbjct: 9025 EILQKREDMEKEKEN------LRREKQETELFRGELQRQRDEV--ESSRQALIMEKDQFK 9076
Query: 1001 LESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFREL 1180
L+ ++E+ + ++ H + + + ++ L ES+ N ++
Sbjct: 9077 LKIDHQRNEMSAAFEKEHKRLENMENDLENQRAKLAESL---------------NDAAKM 9121
Query: 1181 GDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASM 1360
++ Q++N++ + ++ + + +E K++++ L+
Sbjct: 9122 EQKLQQMKNELNKEKEQVEEMKQMV---KTERVKIEQEKEEMRKQTQEIEDGHEKLQKKT 9178
Query: 1361 EMQCSKLKD-ELEEERGK-ISENLE-RISKLQKMNNELAERSKSQNSIXXXXXXXXXXXX 1531
E+ L+D E +R K +S L+ + ++K N E+ + +S + +
Sbjct: 9179 EIADKLLQDANSESDRLKDLSMKLQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLK 9238
Query: 1532 XXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEI 1711
+ + E + + ++ ++ ++E + K +I
Sbjct: 9239 NDRDAYEKDMTHLELKREELVRETEDLERKILQQREQDEMA---------------KRDI 9283
Query: 1712 EKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQ 1891
E + L+ + I K N+ E+++ +S K+ L++ ++N+
Sbjct: 9284 ENQTEALEVMKVDILKKRNEFAKEMENV--------HSERQKLLLLQGALQSQESELENR 9335
Query: 1892 VAVSQEQHIEH------QCKEELEGHIADLVL---NDFSNDILSWSRRKEEAVVHDDEFD 2044
V + +++H++ +C+++L +++ V N++ I R KE+ + ++ +
Sbjct: 9336 VFMEEQKHLKQAKAETEECRKQL-AEMSETVTTEQNEYRKLIEELQREKEQLEISKNQIE 9394
Query: 2045 AERIALLNELKSLHQDLELLKAEEA----VKSLSNNVGVSTKGIHYFSQLIQEGKDGEAS 2212
E+ L N +L + LE L+ E+A K+ + +K I + +E +
Sbjct: 9395 QEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWV 9454
Query: 2213 DVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAIL--AFETADA 2386
+++G+ + + E + +E H E KK+ + L + E ++
Sbjct: 9455 EIEGEKKRMEE---------------------ETRRLEMHREEIKKVDSELQKSRENIES 9493
Query: 2387 SDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDL---KRLLLNEKNGLHAXX 2557
+ + N +E L K K E E E QR + DL K + +++
Sbjct: 9494 REEKINNKMEELL--QMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDII 9551
Query: 2558 XXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKM-LCVLKEELQSKIDSLLKEIKE 2734
+ K K L E L V++++ + K+E++ L KE +E
Sbjct: 9552 DIKIQEKEREIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQE 9611
Query: 2735 KDSNSKVLAEKLSD----------------ALKKSADHAQRESHLLKHIADLE-AGITDR 2863
K L +++ D ALK + ++E+ ++K LE + I +
Sbjct: 9612 LKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEM 9671
Query: 2864 EIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQM---SLRKMLEDKDKLLCLV 3034
++ + E +EKE SL + ET QKQM S KM+E+K+++ L
Sbjct: 9672 QLKIFKQQRLNDQTREENKKEKE---SLEQQRFETEQQKQMLEISTTKMMEEKNEMADLS 9728
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVF-LQSE---EREKIEEQKRVLDQALQECEELK 3202
E K LEK+ +T V +Q+E + + IE+Q +++ EE +
Sbjct: 9729 RELQKAKDE----LEKIAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEKE 9784
Query: 3203 NDIQNKHSDI--------------DSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXX 3340
IQ K +I +++ EE K L M
Sbjct: 9785 LSIQRKEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQKNNKDFELLE 9844
Query: 3341 XISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEA--- 3511
I S L++ + +L+ + E+ K+ +E + +++ KEKE L + Q EQ E
Sbjct: 9845 KIRSELENEKYDLQIWTEQQKHLVEVQLQELE---KEKERLEKMEIELQSKREQTEKEKA 9901
Query: 3512 --------------VLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLK- 3646
V+ +K + + LE+ ++ +E+ EK + L EE ++
Sbjct: 9902 DLNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQI 9961
Query: 3647 --KQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSE 3808
+ EE++ ++ LE++ + K +KE+ + E + K + +I N+E
Sbjct: 9962 EAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEE-QIQNNE 10016
Score = 114 bits (284), Expect = 4e-22
Identities = 231/1252 (18%), Positives = 504/1252 (40%), Gaps = 81/1252 (6%)
Frame = +2
Query: 302 RKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESG 481
R L+ + +E L++ + + D T+KN L +D + +++ +D +D
Sbjct: 5472 RSQLDLRQSE-LDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKS 5530
Query: 482 LYVSNVVSDAVLNGVVSAQE----EEFKEALAAKDSENFLLNKKIEDLNHKIWSL-EETL 646
L L + +E E+ K L + E + ++ ++ ++ + EE +
Sbjct: 5531 LDEDQ--KKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELI 5588
Query: 647 QYKEEVILSSHETISERDRL----------LKDFIHEKDLMQQRAQETEQKLASRDNEMM 796
+ KE + + +T +E+ L + D EK ++++ + + DNE
Sbjct: 5589 REKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENISKLKEYIDNEKE 5648
Query: 797 HMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIED---------QNIKEEIEKQIVET 949
L +D + K+++ + Q QS + IE QN+ E++K+ +
Sbjct: 5649 KSKLREDEL-----KKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKKSEDV 5703
Query: 950 IYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEM-SKQAEISKLSHTLEESIMNS 1126
Q++E+ E +LL + ++++L+ + E SK+ ++ + + E+ M
Sbjct: 5704 --EIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQ 5761
Query: 1127 NLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXX 1306
L + D+I +++ + ++ +A++I + N L E+
Sbjct: 5762 MKTDL----------QIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRK 5811
Query: 1307 XXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQK-----MNNELAE 1471
S++ KD LE+ER + + + K+++ N LAE
Sbjct: 5812 DMVLNEKNRDIEEKIKSIQSD----KDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAE 5867
Query: 1472 RSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVS 1651
K + + E++ + I I +E +++
Sbjct: 5868 IQKEREDV------------------------------EKMNENITREMHEIKHQEEQMN 5897
Query: 1652 GHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLI 1831
D + L+T + N + E+EK ++++ S + + E+D ++N ++
Sbjct: 5898 QKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQFDLRQS----ELDKQQTNMND----IM 5949
Query: 1832 HKVDNSGETLRAFVKNIQNQVA-VSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRR 2008
+ N + L + ++ Q + +E+H Q ++ L+ DL + + +
Sbjct: 5950 ETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLD---KDLKMMKLQKQVFEEEKN 6006
Query: 2009 KEEAVVHDDEFDAERIALL-----NELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYF 2173
K E + + E +A+ I + NE +SL + E LK E K ++ TK
Sbjct: 6007 KLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKE---KESFTHLAEDTKKEQEI 6063
Query: 2174 SQLIQEGKDGEASDVQGKSRAL---RRHSTGQAFREPPKPEDLYTT-----------YSE 2311
++ + +D+Q + L R + + Q K E+L Y +
Sbjct: 6064 LDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQ 6123
Query: 2312 GKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLK---REYELEL 2482
+ +E + A + D + + L +++F + ++ + EL
Sbjct: 6124 QREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTEL 6183
Query: 2483 QRKTEEIYDLKRLLLNEKNGLH--AXXXXXXXXXXXXVAEITGKFEKVLQENKL---LPV 2647
+R+ +EI +K +++ + + E T + + VL E +
Sbjct: 6184 EREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKI 6243
Query: 2648 EEVQRYK-MLCVLKEELQSKIDSLLK---EIKEKDSNSKVLAEKLSDALKKSADHAQRES 2815
+ +Q K ML K +L+ L K +++++ N+ +K + L+K ++ RE
Sbjct: 6244 KSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREM 6303
Query: 2816 HLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSL---SLATKEQETVNQKQM 2986
H +KH E + ++ + L E+ +EKE + S + Q ++++Q
Sbjct: 6304 HEIKH---QEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQT 6360
Query: 2987 SLRKMLE---------DKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQS--- 3130
++ ++E DKDK + E+ +E +++ +++ ++ + + + LQ
Sbjct: 6361 NMNDIMETMKNERKQLDKDKEE--MEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVI 6418
Query: 3131 -EEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXX 3307
EE+ K+E+ K L++ + ++K + QNK ++ + EE +K K + +
Sbjct: 6419 EEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTKREK 6478
Query: 3308 XXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQ 3487
S++ +Q E N EE+K I K++ DI+ KEK+++ R +
Sbjct: 6479 NSLDEMKVAN---ESSMADLQKEKSNL-EEMKENISKQTEDIE---KEKDKIRLR----E 6527
Query: 3488 KAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLK---KQFL 3658
+EQ +A + ++ E E + +E ++A + E + + SL + LK + F
Sbjct: 6528 DELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFE 6587
Query: 3659 SATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQ 3814
+ EEL+ + +LE E + K KL E + +++ E N+E++
Sbjct: 6588 NEKEELKQMKTELEREADEIE--KIKLETQHERQRVEEMTADFMETMNNERK 6637
Score = 111 bits (277), Expect = 3e-21
Identities = 233/1162 (20%), Positives = 476/1162 (40%), Gaps = 76/1162 (6%)
Frame = +2
Query: 524 VVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDR 703
+V+ +EE K+ ++S N + KK +L H+ L + Q E++I S + + +R
Sbjct: 13336 LVNMEEEIKKQRRVLEESMNEMTKKK-SELQHERSELYKQKQQLEDMIASESKRDVDTER 13394
Query: 704 LLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDC 883
+D E+ L ++R + + K +L++ + + ++I + ++ + +
Sbjct: 13395 SRQDKEDEQILKREREEIADMK---------DQLLKEKEDVETTKERINREKEHIEKMQS 13445
Query: 884 FRRDEIEDQNIKEE------IEKQIVETIYVTQIQELGEEHD---LLRLESAKYQDEIQS 1036
D+ E+ +++ + E Q+ +Q+L +E + L ++ K +++
Sbjct: 13446 QLNDQKEEMDLENQKLLYMKTEIQVKTNALEKMMQDLQKERENVNALVIQHQKEREQRDI 13505
Query: 1037 LKDECHAKEMSKQAEISKLSHTLE----------ESIMNSNLESLFTAEIYENTFRELGD 1186
L +E KE +AEI + +E I N E +E EN ++
Sbjct: 13506 LIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTRSEELENLIKKQQK 13565
Query: 1187 QISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEM 1366
+ N+M + ++ + + ++ S+E E+ LK +E
Sbjct: 13566 EFETKENEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILER 13625
Query: 1367 QCSKLKDELEEERGKISENLERISKLQK-MNNELAERSKSQNSIXXXXXXXXXXXXXXXX 1543
+ K EL +E+ ++ + + ++K M +E+ +N +
Sbjct: 13626 E----KSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELE--------------- 13666
Query: 1544 XXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQ 1723
+ + + ++++ IDK + E+ ++I + L K E E +
Sbjct: 13667 -----------DEKKSMLSRLSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKR 13715
Query: 1724 KVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVS 1903
L ++ IEK+ D L + SL L K + E +R K +Q +S
Sbjct: 13716 TQL---DNTIEKMNMDKL-SIQREKDSLEEIKADLQRKAEKLDEEMR---KAVQITSQIS 13768
Query: 1904 QEQHI---EHQCKEELEGHIADL-----------VLNDFSNDILSWSRRKEEAVVHDDEF 2041
Q+ I + + +EEL AD+ L +IL S+ + + + D E
Sbjct: 13769 QDAKILDDDREKEEELRSMRADIERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEK 13828
Query: 2042 DAERIAL-LNELKSLHQDLE-----LLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDG 2203
+R L L EL+ LE + K ++AV SL N V + + + E +
Sbjct: 13829 QRKRNDLTLQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRK- 13887
Query: 2204 EASDVQGKSRALRRHSTGQAFREPPKPEDLYTT-----YSEGKIVEPHPTEEKKLLA--I 2362
E D++ +R++ST + +E D++ ++ + ++ EE++ L I
Sbjct: 13888 EMDDLR-MQLEMRQNSTNKQQQE----VDVFIVENMKMRNDLESMKTLLDEERRQLQDNI 13942
Query: 2363 LAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNG 2542
FE P + +Q ++ +K E E ++++ EEI L + ++ K
Sbjct: 13943 KTFEDQKNVLHPSKTDAVQQ-TDELEKFTTDIKTEKE-HVEKEREEIDVLNKEIIKSKEE 14000
Query: 2543 LHAXXXXXXXXXXXXVAEITGKFEKV-----LQENKLLPVEE----VQRYKMLCVLKEEL 2695
L + EI GK ++ L+ + L ++ VQ K + + E
Sbjct: 14001 LQSLNLEIEMFK----QEIAGKRAQIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEK 14056
Query: 2696 QSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLL-KHIADLEAGITDREIM 2872
+++++ + K+K+ E+L + ++ + +L K ++E +IM
Sbjct: 14057 KTEVELQMNLQKQKNE-----LEELRNTIEAEKHQVENRKIMLDKQQKEVE------DIM 14105
Query: 2873 TSVCS--DVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLE----DKDKLLCLV 3034
T + S DVL +EK L+ E V ++Q L ++LE D + ++
Sbjct: 14106 TVIKSERDVLE-------KEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKII 14158
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLD----QALQECEELK 3202
E + +R+ A L++LKEE E R LQ +++ I+++K L+ + +E LK
Sbjct: 14159 ESEKQSIERERAELKRLKEEVEVQHERTLLQ-QDKNMIQKEKEHLEGEKARTTEEIHNLK 14217
Query: 3203 NDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLE-- 3376
+I+ K S++D L +E E ++ + + +++E
Sbjct: 14218 EEIKRKSSELDMLNKEIEAKRQE----------------------EELHGLPEEIEIEDH 14255
Query: 3377 LRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQ-------KAMEQKEAVLVEKLFE 3535
L+ ++ L+ EI KK D K + + R A TQ K E+++ L E +
Sbjct: 14256 LKKEDDVLREEIIKKQ-QTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRALEETVAT 14314
Query: 3536 GEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTE 3715
++ ++++ + T E ++ RD LN+ +E A +K ++L+ + D++ M E
Sbjct: 14315 TAKQPIVIKLEDTLTSE-VQEMRDHLNNEIKELARMKTIMKMEKDQLKQAKSDIQTQMEE 14373
Query: 3716 TKFLKEKLLVSDENLKEKDLQL 3781
+ E+ + +EK LQL
Sbjct: 14374 FERNMEEAMEEKSRNEEKLLQL 14395
Score = 108 bits (270), Expect = 2e-20
Identities = 257/1319 (19%), Positives = 522/1319 (39%), Gaps = 140/1319 (10%)
Frame = +2
Query: 230 VMDGQGCDISVTSFIEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNF----- 394
+ D Q I S ++ E+ + + K ETL+ ME H +K+++
Sbjct: 10847 IADEQDLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRL 10906
Query: 395 --DLGQDNPGVPGLLEDIRNTKDLLDTVESGL-----YVSNVVSDAVLNGVVSAQ-EEEF 550
DL + + V +D+ N +DLL+ + + + + + VS Q E++
Sbjct: 10907 KEDLEKMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQQRIDE--FDAQVSKQKEQDL 10964
Query: 551 KEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEK 730
+ K+ L K + K + E ++ ++E E E R++ + K
Sbjct: 10965 PKEKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVE-TERK 11023
Query: 731 DLMQQRAQ--------ETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCF 886
+L Q +++ + EQK + N+ M M+ ++ + + +I Q Q +
Sbjct: 11024 ELYQIKSELERVRSEIDHEQK---KLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSE 11080
Query: 887 RRDEIEDQNI-KEEIEK--QIVETIYVT-----------------QIQELGEEHDLLRLE 1006
++I+ N+ K +IEK +IVE + V + Q++ +E +LL
Sbjct: 11081 LDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQN 11140
Query: 1007 SAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGD 1186
AK Q+E + +K EI K TL E ++ E I E T R D
Sbjct: 11141 KAKLQNENERIK--------KVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKED 11192
Query: 1187 QISQLRNDMYSKNSYI----DSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKA 1354
+ ++ D+ + ++ D L + ++ E +LQ++ A
Sbjct: 11193 -LEKMSTDINEQKLHLKNQRDLLEQEREEINHEMTQLQQRIDE--------------FDA 11237
Query: 1355 SMEMQCSKL-KDELEEERGKISENLERI------SKLQKMNNELAERSKSQNSIXXXXXX 1513
+ Q L K E+EEER + E RI ++LQ++ E E + + +
Sbjct: 11238 QVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRV------ 11291
Query: 1514 XXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLS 1693
+V M +L ++ ++ S ID ++ +++ I + L
Sbjct: 11292 --------------IVEME-REELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLE 11336
Query: 1694 NQKFEIEKSQKVLQSFESHIEKLVNDS---LHEVDSAFCSLNSRFYSLIHKVDNSGETLR 1864
K EI ++ ++ S ++ + + H+++++ L+ KV+ + +R
Sbjct: 11337 KMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENS----KEIVQKLMVKVEEQRKDIR 11392
Query: 1865 AFVKNIQ-NQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEF 2041
+ + + ++ EQ + Q K +L+ N+ ++ ++++E + E
Sbjct: 11393 LQKEELDIERQKIADEQGLVVQNKAKLQNE------NERIKEMDEEIKKEKETL---KEM 11443
Query: 2042 DAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQ 2221
+A E++S+ ++ + K E+ ++ +S +V + + L+++ E ++
Sbjct: 11444 EAHLRKEKEEMRSVIEETQRRKKED-LEKMSTDVNKQNQDLMNQRDLLKQ----EREEIN 11498
Query: 2222 GK-SRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSP 2398
K ++ +R A K EDL + K+ E + E+ + I+ +T +
Sbjct: 11499 HKWTQLQQRIDEFDAQVSKQKEEDL---TKQKKMEEERKSLEETKIKIIEMKTKTEPEKI 11555
Query: 2399 LRNWPKEQ------LLGHFKQSFAGLKREYE---LELQRKTEEIYDLKRLLLNEKNGLHA 2551
+ KE+ + K+ +K + E E+ + +++ D K+++ EK L
Sbjct: 11556 KKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEK 11615
Query: 2552 XXXXXXXXXXXXVAEITGKFEKVLQEN-------------KLLPVEEVQRYKMLCVLKEE 2692
E + K+ Q + + L VE ++ K + + KEE
Sbjct: 11616 MKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEE 11675
Query: 2693 L-----------------QSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHL 2821
L ++K+ + + IKE D K K + LK+ H ++E
Sbjct: 11676 LDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHLRKEKEE 11731
Query: 2822 LKHI---------ADLEAGITD-----------REIMTSVCSDVLTALFVEMVREKEFSL 2941
++ + DLE TD R+++ ++ R EF
Sbjct: 11732 MRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDA 11791
Query: 2942 SLA-TKEQETVNQKQM-SLRKMLED-KDKLLCLVGEENKEHKRQIAILEKLKEETENNPG 3112
++ KE++ QK+M RK LE+ K K++ + + E ++ EK KEE E
Sbjct: 11792 QVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKK----EKEKEEEEVMRA 11847
Query: 3113 RVFLQSEE-----------REKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEK 3259
+V ++ EE R +I+ +++ L+ + E+ K D++ S+I R++ E+
Sbjct: 11848 KVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEE 11907
Query: 3260 LNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDL 3439
+L + ++ + E++ EEL E +K + + DL
Sbjct: 11908 ERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDL 11967
Query: 3440 LIKEKEEL---NERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDL 3610
LI+ K EL NER+ + ++++ L E E++ ++S TR Q E +
Sbjct: 11968 LIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSITEETRRQKEDLEKM 12027
Query: 3611 LNSLTEEHADLKKQ---FLSATEELQSKERDLEVAMTE----TKFLKEKLLVSDENLKE 3766
+ E+ DL+ Q EE+ K + L+ + E KE+ L ++ +KE
Sbjct: 12028 STHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKE 12086
Score = 107 bits (266), Expect = 5e-20
Identities = 223/1154 (19%), Positives = 456/1154 (39%), Gaps = 85/1154 (7%)
Frame = +2
Query: 596 KKIEDLNHKIWSLEETLQYKEEVILSSHETIS-ERDRLLKDFIHEKDLMQQ-RAQETEQK 769
K IE +I E L+ ++ + S +T+ ER L K KDL +Q +Q + +
Sbjct: 2854 KDIETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHE 2913
Query: 770 LASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIV-E 946
+ + + +LE+ + LS K+ +L+ + DCF +++ D +++EE+++Q E
Sbjct: 2914 IQLAEIQKEREILEQLKLTLSKQKE-DLEKER----DCFEKEKA-DISLREELQEQSERE 2967
Query: 947 TIYVTQIQELGEEHDLLR--------LESAKYQDEI---QSLKDECHAKEMSKQAEISKL 1093
I T+++ E +L + LE+ + Q +I + K E E+ K+AE ++
Sbjct: 2968 GIGKTRVRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEK 3027
Query: 1094 SHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSE 1273
E +N E + + N +++ ++R++ + L S D L E
Sbjct: 3028 QRRDIEKDRRNNEEMVIKLQ---NEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKE 3084
Query: 1274 -------------CNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERG-- 1408
K E + +++ SK K++LE+ER
Sbjct: 3085 RFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCF 3144
Query: 1409 -------KISENLERISKLQKMNN-------ELAERSKSQNSIXXXXXXXXXXXXXXXXX 1546
+SE+L+ S+ + ++N E+ E K++ ++
Sbjct: 3145 EKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDE 3204
Query: 1547 XXXVVNM-------AFGSKLEELTDQINI--FNSVIDKKEAEVSGHLDTISSLQTVLSNQ 1699
+ + A +KLE ++ N+ + + K V + + Q VL N
Sbjct: 3205 RDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKKDRENVESLAEELGRKQVVLENM 3264
Query: 1700 KFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKN 1879
+ E E +K +S + E+++ + V + K D + L KN
Sbjct: 3265 QIETEMQRKANESNKQMQERVLIELKKTVTDIAGA----------KEDLENQLLEEREKN 3314
Query: 1880 IQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVH--DDEFDAER 2053
Q + E+ + + K+ + D+V + + +A+++ DE +A R
Sbjct: 3315 KVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQLRLREVELEQLQALIYRQQDEIEANR 3374
Query: 2054 IALLNELKSLH-QDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKS 2230
A++NE L Q E+ + + V + + Y S KD + +
Sbjct: 3375 KAIINEKYRLEGQKTEIDRLQREVNQM----------MEYAS------KDRANLEKEKSE 3418
Query: 2231 RALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNW 2410
++H D+ G I EE+ + + D + L
Sbjct: 3419 MIAQKHQM-----------DIELNKERGLI------EERTQMLNTYEKEMDQKRTALEVE 3461
Query: 2411 PKEQLLGHFKQSFAGLK---REYELELQRKTEEIYDLKRLLLNEKNGLH--AXXXXXXXX 2575
KE L + KQ+ K ++ ++ELQR+ ++I LK NE+ L A
Sbjct: 3462 MKE--LKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKD 3519
Query: 2576 XXXXVAEITGKFE---KVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSN 2746
+AE T + + KVL E+ L +++ K L+ +S+ K+ + DS
Sbjct: 3520 DLAHLAEDTKRKDDEMKVLHESALADIQKE---------KCNLEQMRESMFKQNEMIDSE 3570
Query: 2747 SK--VLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMV 2920
K +L E ++ + Q E K I + +R MT D++T L +
Sbjct: 3571 KKKMILREDKLQQMQAEINRQQTEMDTKKSIIE-----NERAAMTKKNQDLMTEL-TKQS 3624
Query: 2921 REKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETE 3100
+ E + E+E + + L+K +E+ + L ++ ++ E LK++ E
Sbjct: 3625 EDVEIQMKEVLTEKELLESDRKLLKKDVENLQQKLLIIESDS----------ESLKQDRE 3674
Query: 3101 NNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRC 3280
L E+E +++ K L +E E++K + Q++ ++ + + +K + L+
Sbjct: 3675 -------LLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQK 3727
Query: 3281 MXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEEL-----------------KNE 3409
M LD ++ E++N +EL ++E
Sbjct: 3728 MNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLKQSE 3787
Query: 3410 IEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQ 3589
++K+ T+++ +I+ + ++L ++ ME+++ + ++ + +Q L+ + Q
Sbjct: 3788 LDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQ 3847
Query: 3590 TEKYRDLLNSLTEEHADLKK---QFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENL 3760
+ + + N L + +L++ + EE+Q++ + LE E K KE E+
Sbjct: 3848 KQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESFTHLAEDT 3907
Query: 3761 KEKDLQLRAFEIAN 3802
K++ L ++AN
Sbjct: 3908 KKEQEILDEIKVAN 3921
Score = 107 bits (266), Expect = 5e-20
Identities = 244/1167 (20%), Positives = 478/1167 (40%), Gaps = 76/1167 (6%)
Frame = +2
Query: 536 QEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKD 715
QE + +A K E ++ +KIE E +Q +++ + S E + ++ + +K
Sbjct: 7908 QELDLIQAKVVKQKEE-MVKQKIES--------EREIQQEKKKLQRSEEELEDKMQKIKR 7958
Query: 716 FIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNI------ILSLHKQIELQSQNTQSL 877
+ E L+Q ET+ K DN+M + ++D + + S K++E+ +
Sbjct: 7959 EMIELKLLQD---ETDGKRKDVDNKMRQVARKRDELEKMKADVESASKKLEVDRVMLNT- 8014
Query: 878 DCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDL------LRLESAKYQDEIQSL 1039
RDE+E + + + +++ + +LGE+ + L E+ K S
Sbjct: 8015 ---ERDELERIKTESQRATEHMQSHAEERAGDLGEKEPVNTRIQRLIQEAEKASKMAWST 8071
Query: 1040 KDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTA-EIYENTFRELGDQISQLRNDMY 1216
K H EM Q E+S ++E M++N++ + E T R + D++ R +
Sbjct: 8072 K---HEPEMRMQREVSVEEESVERQDMSANMQRMILEIEHARETLRGMKDEVQAARKE-- 8126
Query: 1217 SKNSYIDSLASRIDFLSSECN--KLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDE 1390
S ++++ +++FL+ + N K EQ S +M S+ +++
Sbjct: 8127 --RSELENM--KLEFLTMKKNMEKTYEQQNDEIQKEKQQIE-------SSKMLLSRERND 8175
Query: 1391 LEEERGKISENLERISKLQKMN----NELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXV 1558
LE+ R + E ++I L K NEL ER K+ +
Sbjct: 8176 LEQNRADL-ERQKQIMALDKQKLLAENELLEREKAD--VIKIIENLESLREEATRERATE 8232
Query: 1559 VNMAFGSKLEELTDQINIFNSVIDKKEA------EVSGHLDTISSLQTVLSNQKFEIEKS 1720
A EEL ++ S+ D +EA E+ +D + L+ L Q+ E++K+
Sbjct: 8233 TAQATRRDSEELMQKMEAL-SMEDFQEASKNQMVELKRQIDKLIELKADLLQQQTELKKT 8291
Query: 1721 QKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAV 1900
+ L+ +EK +R L H+ D +T + IQ Q
Sbjct: 8292 KADLKQQMDDLEK-----------------TRSEILKHEKDTDSKTRELELIEIQRQ--- 8331
Query: 1901 SQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALL---NE 2071
K++LE I L L ++L + E V+ + D + ++ +E
Sbjct: 8332 ----------KDDLETRIQKLTLEKRDLEVL-----RSEIVLEKKDLDQKMKQVIRKRDE 8376
Query: 2072 LKSLHQDL-----ELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQ-----EGKDGEASDVQ 2221
++ + D+ E+ + + ++ L NNV + H F L++ E ++ A+D++
Sbjct: 8377 MEKIRSDIANATEEINRERQELEILRNNVQSAR---HDFELLLERTANLEDEESAATDIE 8433
Query: 2222 G------KSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETAD 2383
K R + R+ G+ R K + VE +EK++
Sbjct: 8434 RLVLEVVKIREMVRNLKGEMERRMEKSK-----------VE---IDEKEIFK-------- 8471
Query: 2384 ASDSPLRNWPKEQLLGHFKQSFAGL----------KREYE---LELQRKTEEIYDLKRLL 2524
S ++ + ++ +G +++ GL KRE E EL K +E ++ +L
Sbjct: 8472 ---SEIQRFIQD--IGQIRENLGGLGEEIEKTRRDKRELEKMRAELAEKQQEQESMREML 8526
Query: 2525 LNEKNGLHAXXXXXXXXXXXXVAEITGKF-EKVLQENKLLPVEEVQRYKMLCVLKEELQS 2701
E+ L EI + E V+ + ++ ++Q+YK EELQS
Sbjct: 8527 HKEREELEQLKDEINREKED--VEIRRELVEAVIDKEEMKEFTDIQKYK------EELQS 8578
Query: 2702 KIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSV 2881
+ LL + ++ D + + + + + H ++ + L +L+ G E +
Sbjct: 8579 VTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFELKKG----EQLLEK 8634
Query: 2882 CSDVL--TALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEH 3055
D L VE ++ K+ SL E +N M + + ED DK + +E +E
Sbjct: 8635 QKDELKENGWIVEEIKNKKDSL-------EKIN---MEILRKNEDMDKEKGKLRQEKQEM 8684
Query: 3056 KRQIAILEKLKEETENNPGRVFLQSEE----REKIEEQKRVLDQALQ-------ECEELK 3202
+ L++ +E+ E + ++ + E R +I +K+ LDQ ++ E E+++
Sbjct: 8685 DLFRSELQRQREDLETSIQKLTHEKREMEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIR 8744
Query: 3203 NDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELR 3382
DI N +ID R+E E L ++ S+ D +L R
Sbjct: 8745 FDIANARVEIDGERQELEILRDNVQ-----------------------SARQDFERLVER 8781
Query: 3383 NYNEELKNEIEKKSTDIDLLIKEKEELNERL----AYTQKAMEQKEAVLVEK-LFEGEQK 3547
N E++ E +TDI+ L+ E ++ E + ++ ME+ + + EK +F+ E +
Sbjct: 8782 TANLEVE---ESAATDIERLVLEVVKIREMVRNLKGEMERRMEESKVEIDEKEIFKSEIQ 8838
Query: 3548 ILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFL 3727
L+ + Q RE + + + + ++L+K E+ Q +E E+ E + L
Sbjct: 8839 RLIQDIGQ--IRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQEEESMREILQKEKEEL 8896
Query: 3728 KEKLLVSDENLKEKDLQLRAFEIANSE 3808
++ L D N +++D+++ + E+ SE
Sbjct: 8897 EQ--LKKDINREKEDIEI-SRELVESE 8920
Score = 106 bits (265), Expect = 7e-20
Identities = 223/1183 (18%), Positives = 477/1183 (40%), Gaps = 92/1183 (7%)
Frame = +2
Query: 536 QEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKD 715
+EE + + K E + ++E + +I ++ L +++I E + +++ +
Sbjct: 11563 EEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDL---EKMKSE 11619
Query: 716 FIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNT----QSLDC 883
+ ++ M++ E + K+ D E H + I+ L ++E Q ++ + LD
Sbjct: 11620 IMKQRQQMEEERSELDNKIKQTDLER-HDIENSKEIVQKLMVEVEEQRKDIRLQKEELDI 11678
Query: 884 FRRDEIEDQNIKEEIEKQIV-ETIYVTQI-QELGEEHDLLRLESAKYQDEIQSLKDECHA 1057
R+ ++Q + + + ++ E + ++ +E+ +E + L+ A + E + ++
Sbjct: 11679 ERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEE 11738
Query: 1058 KEMSKQAEISKLSHTLEESIMN-SNLESLFTAEIYENTFR---------ELGDQISQLRN 1207
+ ++ ++ K+S + + + N L E E + E Q+S+ +
Sbjct: 11739 TQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKE 11798
Query: 1208 DMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEM------- 1366
+ +K ++ ++ + +++ + ++A +EM
Sbjct: 11799 EDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQ 11858
Query: 1367 ---QCSKLKDELEEERGKISENLERISK----LQKMNNELA--------ERSKSQNSIXX 1501
Q +++ E++ E+ K++++ + I + L+KM +E+ ERS+ +N I
Sbjct: 11859 IKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQ 11918
Query: 1502 XXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQ 1681
+V ++EE +I +D + +++ D + +
Sbjct: 11919 TYIEKCDIENSKEIVQKLMV------EVEEQKHEIQFQKEELDIERQKIADEQDLLIQNK 11972
Query: 1682 TVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETL 1861
+ L N+ I+ +V+ K ++L E+++ S+ + E L
Sbjct: 11973 SELQNENERIKNINEVI--------KKERETLKEMEAYLEKEKEEMKSITEETRRQKEDL 12024
Query: 1862 RAFVKNI--QNQVAVSQEQHIEHQCKEELEGHIADLV--LNDFSNDILSWSRRKEEAVVH 2029
+I Q Q SQ +E + +EE+ L +++F + S++KEE +
Sbjct: 12025 EKMSTHINEQKQDLRSQRDLLEQE-REEINHKWKQLQQRIDEFDAQV---SKQKEEDLPK 12080
Query: 2030 DDEFDAERIAL------LNELKSLHQDLELLKA---EEAVKSLSNNVGVSTKGIHYF-SQ 2179
+ E +R +L + E+K+ + E+ K EE + + V + K I SQ
Sbjct: 12081 EKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQ 12140
Query: 2180 L--IQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKL 2353
L ++ D E + + + + EDL SE EE+
Sbjct: 12141 LERVRSEMDHEQKKLNDDKKMIEQEK-----------EDLEKMKSEIMKQRQQMEEERSE 12189
Query: 2354 LAILAFETADASDSPLRNWPK--EQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLL 2527
L +T D + N + E+L+ + K+++E++ Q+ E D++R +
Sbjct: 12190 LDKKIKQT-DLEKHDIENSKEIVEKLMVEVE------KQKHEIQFQK---EELDIERQKI 12239
Query: 2528 NEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKI 2707
++ L + E+ E++ +E + L EV K KEE++S I
Sbjct: 12240 ADEQDLLIQNKIEQQNENERIKEMD---EEIKKERETLKEMEVNLQKE----KEEIESVI 12292
Query: 2708 DSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCS 2887
+ + ++ + S + E+ D + + Q + + L+ I + E S
Sbjct: 12293 EETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFE----TTS 12348
Query: 2888 DVLTALFVEMVREKEFSLSLATKEQETV----NQKQMSLRKMLEDKDKLLCLVGEENKEH 3055
++L +E E + L A KE E++ N+K+ L ++ D+ ++NK
Sbjct: 12349 NILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTELEEIEVDQS-------QQNKNV 12401
Query: 3056 KRQIAILEKLKEETENNPGRVFLQSEERE--------KIEEQKRVLDQALQECEELKNDI 3211
+ +LEK +++TE + Q+++ E K E KR LD+ + E+ N+I
Sbjct: 12402 ETMKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEI 12461
Query: 3212 QNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYN 3391
+ D++ +E+++ + K + LD +Q E++N
Sbjct: 12462 LRQRDDLE--KEKEDMMKKW--------------------------NELDGLQKEIQNQK 12493
Query: 3392 ---EELKNEIEKKSTDIDLLIKEKEELNERLAYT--------------QKAMEQKEAVLV 3520
EE+K E+E K +I IKE++ L E L +K +Q E + V
Sbjct: 12494 NEMEEIKCELETKRIEI---IKEQKRLEESLNTVNEERQYLEIVRVDYEKHQQQIEEMRV 12550
Query: 3521 EKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEEL-------Q 3679
+ E ++ L+ + R++ E+ +D++ L +E K + EEL Q
Sbjct: 12551 KTKMERDELDQLM-AKMLMDRKENERSKDMIGLLKKEMEQTKFNLDAQEEELKLEKQKIQ 12609
Query: 3680 SKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSE 3808
++++DLE+ E K ++ E EKD +AFE E
Sbjct: 12610 NEKKDLEMFKAEIKREASEVKTLKEQQLEKD--TKAFEALKEE 12650
Score = 105 bits (263), Expect = 1e-19
Identities = 245/1365 (17%), Positives = 518/1365 (37%), Gaps = 201/1365 (14%)
Frame = +2
Query: 320 KIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGLYVSNV 499
K E L+++++ L+ +L + + ED+ N K+ L E L+
Sbjct: 6059 KEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLREDELWQ--- 6115
Query: 500 VSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLE---ETLQYKEEVIL 670
L + Q+ E ++ +SE + K +EDL HKI SL+ E+L+ E
Sbjct: 6116 -----LQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFE 6170
Query: 671 SSHETISERDRLLKDFIHEKDLMQQRAQETEQKLAS------RDNEMMHMVLE----KDN 820
+ E + + L+ E + ++ Q Q++ +D + ++ ++E KD
Sbjct: 6171 NEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDM 6230
Query: 821 IILSLHKQIELQSQNTQSLDCFRRDEIED--------QNIKEEIEKQIVETIYVTQIQEL 976
++ ++ IE + ++ QS E D +KE++EKQ T+ QIQ+
Sbjct: 6231 VLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTL--AQIQKE 6288
Query: 977 GEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEI 1156
E+ + + + EI+ +++ + KQ E+ +L + I N E EI
Sbjct: 6289 REDLEKMNENITREMHEIKHQEEQMN----QKQDELDQL----KTEIQNLQQELEKEKEI 6340
Query: 1157 YENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXX 1336
+L + S+L + N ++++ + L + +++EQ
Sbjct: 6341 IMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQS 6400
Query: 1337 XXTLKASMEM-------------QCSKLKDELEEERGKISENLERISKLQKMNNELAERS 1477
+L ++M + ++K ELE E I + E +++ ++AE
Sbjct: 6401 RKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEEL 6460
Query: 1478 KSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGH 1657
K + V N + + L++ + I K+ ++
Sbjct: 6461 KKERK-DVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKE 6519
Query: 1658 LDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEK----LVNDSLHEVDSAFCSLNSRFYS 1825
D I + L + EI K Q + +S+IE+ ++ D + ++ S SL+ S
Sbjct: 6520 KDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKD-VEDLQSKIISLDRDAES 6578
Query: 1826 LI---HKVDNSGETLRAFVKNIQNQV----AVSQEQHIEHQCKEELEGHIADLVLND--- 1975
L +N E L+ ++ + + E E Q EE+ + + N+
Sbjct: 6579 LKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQ 6638
Query: 1976 FSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAE-------------- 2113
+ + +K+E D+ D R +L +LK + ++L+ E
Sbjct: 6639 LDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLERE 6698
Query: 2114 -EAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTG----------- 2257
+ + + + + + ++E ++ A +++ K++ L +
Sbjct: 6699 ADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLADLQKE 6758
Query: 2258 ----QAFRE--PPKPEDLYTTYSEGKIVEPH----PTEEKKLLAILAFETADA-SDSPLR 2404
+ RE + ED+ + K+ E TE +K + + E + S+
Sbjct: 6759 KRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAAM 6818
Query: 2405 NWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXX 2584
K+ ++ K K+ ++E+Q K EI K LL N++N L
Sbjct: 6819 IREKQNMMTELK------KKSEDVEMQMK--EILTEKELLHNDRNLLKKDVEDLQQKLMS 6870
Query: 2585 XVAEITG-KFEKVLQEN----------------------KLLPVEEVQRYKMLCVLKEEL 2695
+ K +K EN KL E QR + ++
Sbjct: 6871 IERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKE 6930
Query: 2696 QSKIDSLLKEIKEK-----DSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITD 2860
+ +I++L++EIK+K +S +++ EK + +S D + +S K ++E + +
Sbjct: 6931 REEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRS-DLEKAKSQTFKQNKNIEIALAE 6989
Query: 2861 REIMTSVCSDVLTALFVEMVR--EKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLV 3034
+ + + + + ++ +++ + LA +E E ++ +++ E KD LL +
Sbjct: 6990 IQQKRNALEKMSKEISRDRMKLEDEKKEIQLAREELERMHG---DMQRQQEAKDHLLSGI 7046
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGR-----------VFLQS----------------- 3130
+E+ K + I+ + + + P R VF+Q
Sbjct: 7047 TDESLLKKSEAEIVLQPSQVDKAKPARKTEISDSDKQPVFVQQMPEMDLKDALKKDFESE 7106
Query: 3131 -------------------------EEREKIEEQKRVLDQALQECEELKNDIQNKHSDID 3235
+E +K+++ + L + + E+ K D+QN+ +D
Sbjct: 7107 KLDLPKVKDVLPQDQQMKLEQKLIEDEMDKLKQMRAELQKEADQIEKKKQDMQNERQKLD 7166
Query: 3236 SL-------REEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNE 3394
+ R E+LN+++ ++ + ++ E+ N+
Sbjct: 7167 DMAARLQEERRTNERLNEEINIQKVNQQKQATAFQME-------KTDFERIKTEIDQANK 7219
Query: 3395 ELKNEIEKKSTDIDLLIKEKEELNERLAYTQK-------------AMEQKEAVLVEKLFE 3535
EL ++ EK I + KE+E L E A K + E + A L E + +
Sbjct: 7220 ELADQQEKNKKTITEMQKERETLEEMRANISKQVETITNENKSLSSRESELAKLQEDILQ 7279
Query: 3536 GEQKILLLESS---QSATREQTEKYRDLLNSLTEEHADLKKQFLSATE----ELQSKERD 3694
+Q++ L+++ + +Q + DLL ++ D K ++ E E+ ++ R+
Sbjct: 7280 QQQEMDELKNTIMMEMCQLDQRQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQTRN 7339
Query: 3695 LEVAMTETKFLKEKL------LVSDENLKEKDLQLRAFEIANSEK 3811
++ M K KE L +++L EK+ +L + +++K
Sbjct: 7340 IKSDMVSLKMEKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDK 7384
Score = 104 bits (259), Expect = 3e-19
Identities = 222/1208 (18%), Positives = 484/1208 (40%), Gaps = 43/1208 (3%)
Frame = +2
Query: 326 AETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGLYVSNVVS 505
+E + ME + TLK L +D + ++E+ K+ L+ + +G+ V
Sbjct: 10296 SEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNV----- 10350
Query: 506 DAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHET 685
Q++E K + E +N K +I + ++ ++E L++ +
Sbjct: 10351 ----------QKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEEDLTNQKK 10400
Query: 686 ISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQN 865
+ E + L++ ++ K + + E E H + +K + +L +QI + +
Sbjct: 10401 MEEERKCLEE-VNGKIIEMKTKAELEH----------HEINQKIEELQTLQEQIMKEKEK 10449
Query: 866 TQSLDCFRRDEIED-QNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLK 1042
+++ + E ED IK E+ ++ E + + ++L ++ ++ E +++++ +K
Sbjct: 10450 AEAMTIKLKMEREDLDQIKSELVREKTEVDH--EQKKLNDDIKMIEQE----KEDLEKMK 10503
Query: 1043 DECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSK 1222
E ++ + E S+L + ++++ + + + + EI E E+ +Q +++
Sbjct: 10504 SEIMTQKQEMEKERSELDNKIQQTDLEKH-DIEKSKEIVEKLMFEVEEQRHEIQLQKEEL 10562
Query: 1223 NSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELE-- 1396
+ +A D L ++LQ + TLK ME K K+E++
Sbjct: 10563 DIERQKIADEQDLLIQNKSELQNENERIRNINEVIKKERETLK-EMEAHLEKEKEEMKSI 10621
Query: 1397 -EERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAF 1573
EE + E+LE++S K N+ + K ++ +
Sbjct: 10622 TEETRRQKEDLEKMSTDIKEQNQ--DLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQVS 10679
Query: 1574 GSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHI 1753
K E+LT Q + ++K E +T + + + + + E K +K + E +
Sbjct: 10680 KQKEEDLTKQKEMKE---ERKSLE-----ETKARIIEMKTKAELEDIKKEKEKEEEEEEM 10731
Query: 1754 EKLVNDSLHEVDSAFCSLNSRFYSLIH---KVDNSGETLRAFVKNIQNQVA--VSQEQHI 1918
V E+D L + H K+++ + + +N++ + + Q Q +
Sbjct: 10732 RVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKSEIMKQRQQM 10791
Query: 1919 EHQCKEELEGHIADLVLN--DFSND-------ILSWSRRKEEAVVHDDEFDAERIALLNE 2071
E + + ELE I + D N ++ +K E +E D ER + +E
Sbjct: 10792 EEE-RSELENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADE 10850
Query: 2072 LKSLHQDL-ELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRH 2248
L Q+ EL E +++L+ + + + +++ K+ E V ++R L+
Sbjct: 10851 QDLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKE-EIKSVSEETRRLKED 10909
Query: 2249 STGQAFREPPKPEDLYTTYSEGKIVEPHPTEE----KKLLAILAFETADASDSPLRNWPK 2416
+ + +DL ++ ++E E K+L + A S ++ PK
Sbjct: 10910 LEKMSTDVNKQNKDLM---NQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPK 10966
Query: 2417 EQLLGHFKQSFAGLKREY-ELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVA 2593
E+ + ++S K E++ + + EEI K E+ +
Sbjct: 10967 EKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELY 11026
Query: 2594 EITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLS 2773
+I + E+V E + KM+ KE+L+ ++K+ ++ + L K+
Sbjct: 11027 QIKSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKI- 11085
Query: 2774 DALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLAT 2953
++++L KH D+E +++ L VE V E+ + L
Sbjct: 11086 -----------QQTNLEKH--DIEKS-----------KEIVEKLMVE-VEEQRKDIQLQK 11120
Query: 2954 KEQETVNQKQMSLRKML-EDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQS 3130
+E + QK + +L ++K KL E++R + E++K+E E
Sbjct: 11121 EELDIERQKIADEQNLLVQNKAKL-------QNENERIKKVDEEIKKERET-------LR 11166
Query: 3131 EEREKIEEQKRVLDQALQECEELKNDIQNKHSDI-----------DSLREEQEKLNKQLR 3277
E ++++K L ++E + K D++ +DI D L +E+E++N ++
Sbjct: 11167 EMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREEINHEMT 11226
Query: 3278 CMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEEL-KNEIEKKSTDID------ 3436
+ +D ++ E+L K E+E++ ++
Sbjct: 11227 ---------------------QLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARI 11265
Query: 3437 LLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLN 3616
+ +K K EL E + ++ E++ V+VE +++ ++S R + + + LN
Sbjct: 11266 IEMKTKAELQEIMQEKEEEDEEEMRVIVEM---EREELNQIKSELKRVRSEIDHEQKKLN 11322
Query: 3617 SLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEI 3796
D KK E+L+ + ++ MT+ + ++E+ D +K+ DL+ +I
Sbjct: 11323 -------DDKKIIEQEKEDLEKMKSEI---MTQRQQMEEERSELDNKIKQTDLE--RHDI 11370
Query: 3797 ANSEKQYQ 3820
NS++ Q
Sbjct: 11371 ENSKEIVQ 11378
Score = 102 bits (255), Expect = 1e-18
Identities = 220/1188 (18%), Positives = 496/1188 (41%), Gaps = 26/1188 (2%)
Frame = +2
Query: 296 DTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVE 475
D +S+ +AE E++ I L++ +L ++ + + E+ + ++ +D +
Sbjct: 2071 DKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIR 2130
Query: 476 SGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYK 655
G+ + + + + ++ A +++ + K I+++ +++ QY
Sbjct: 2131 VGIEKQEITFKDL--------KADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQKERQYM 2182
Query: 656 EEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLAS--RDNEMMHMVLEKDNIIL 829
+ ++ + D + + E+ ++ + E EQ+ + D + EK+NII
Sbjct: 2183 DRLVEEIEKRTKALDEMQMEVDKERQEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQ 2242
Query: 830 SLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLES 1009
+ +I+ +S N E++ +NI +E TI+ EL +EH LR
Sbjct: 2243 A---EIQKESDNL---------ELQSENISKE------RTIF-----ELEKEHLGLRENE 2279
Query: 1010 AKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQ 1189
A+Y+ Q DE K ++ ++ ++ ++ E + TA E T
Sbjct: 2280 AEYK---QKQIDELQNKLRMEKVQVEQMQ--ADKDQQRKKAEYVKTARGRETT------A 2328
Query: 1190 ISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQ 1369
+ + R +M +SL + + + + EQ +K E +
Sbjct: 2329 LEEQRQEM-------ESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKYKE-K 2380
Query: 1370 CSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXX 1549
K ++L+ +R + ++++ ++ E ER K + I
Sbjct: 2381 LDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEI---QKPAVYTETYMLETQ 2437
Query: 1550 XXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKV 1729
VV + +L+E+ +IN S ++K+++ + IS ++ + EK +
Sbjct: 2438 KPVVEKSKTDELDEVRKKINADLSEVEKQKSALVQMNLKISQEESYVKK-----EKDRLK 2492
Query: 1730 LQSFESHIE-KLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQ 1906
LQ E +++ +N +E+D + + L + +D + + +V +++
Sbjct: 2493 LQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMD----------RLEKEKVEITK 2542
Query: 1907 EQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLH 2086
E+ ++ + E++ A S D++ K+E + D + R L EL+ +
Sbjct: 2543 EKQRVNEMQNEVKRKNA-------SVDLI-----KQEVLREQDHIENSREILNRELEKIK 2590
Query: 2087 QDLELLKAE-EAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRAL---RRHST 2254
+ +L E EA+ +G + + +Q+ EA D + + R + RR++
Sbjct: 2591 EKKTILAEEFEALDDKKEMIGKEMQRLGKMKAELQK----EAEDTEKQRRDIDNDRRNNE 2646
Query: 2255 GQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGH 2434
+ + +D+ T+ + E + +K+ L +T + L E +
Sbjct: 2647 EMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLE-SDRDTLEKERFDLEKTKTE--MKD 2703
Query: 2435 FKQSFAGLKREYEL---ELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITG 2605
++ R++E+ E+Q++ E + LK L +K L A+I+
Sbjct: 2704 LEKQLESQSRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEK----ADISL 2759
Query: 2606 KFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSN--SKVLAEKLSDA 2779
+ E Q K E + + ++ +K+E+ + L +KE ++N K + E D
Sbjct: 2760 REELEEQSEK----EGIDKTRVR--IKQEMDELEQTRLNVVKELENNELQKQIIEDERDK 2813
Query: 2780 LKKSADHAQRES-HLLKHIADLEAGITDREIMT----SVCSDVLTALFVEMVREKEFSLS 2944
+++ Q+E+ K D+E + E M + D+ T+ + +R++E +L
Sbjct: 2814 IEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETS--TDRIRDEEANLR 2871
Query: 2945 LATK----EQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPG 3112
+ + +++T+ +++ L+K + L + +N++H+ Q+A ++K
Sbjct: 2872 VLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQK---------- 2921
Query: 3113 RVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXX 3292
ERE +E+ K L + ++ E+ ++ + + +DI SLREE ++ +++
Sbjct: 2922 -------EREILEQLKLTLSKQKEDLEKERDCFEKEKADI-SLREELQEQSER------- 2966
Query: 3293 XXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELK-NEIEKKSTDIDLLIKEKEELNE 3469
I +D ++ N +EL+ NE++K+ ++ E++++ +
Sbjct: 2967 --------EGIGKTRVRIKKEMDELKQTRLNVVKELENNELQKQ-----IIEDERDKIEQ 3013
Query: 3470 RLAYTQKAME--QKEAVLVEK-LFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHAD 3640
A QK E +K+ +EK E+ ++ L++ + T++ RD E + +
Sbjct: 3014 IKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETSTDRIRD-----EEANLE 3068
Query: 3641 LKKQFLSATEELQSKER-DLEVAMTETKFLKEKLLVSDENLKEKDLQL 3781
++KQ L + + KER DLE TE LK++L + +++ ++QL
Sbjct: 3069 VQKQRLESDRDTLEKERFDLEKTKTEMGNLKKQL---ESQIRQHEIQL 3113
Score = 101 bits (252), Expect = 2e-18
Identities = 227/1221 (18%), Positives = 499/1221 (40%), Gaps = 47/1221 (3%)
Frame = +2
Query: 257 SVTSFIEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLE 436
SVT + + LD S + +T+E + I G L+ + F+L + LLE
Sbjct: 8578 SVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFELKKGEQ----LLE 8633
Query: 437 DIRNTKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLN 616
KD L E+G V EE K + + N + +K ED++
Sbjct: 8634 ---KQKDELK--ENGWIV-----------------EEIKNKKDSLEKINMEILRKNEDMD 8671
Query: 617 HKIWSLEETLQYKEEVILSSHETISERDRL---LKDFIHEKDLMQQRAQETEQKLASRDN 787
+ L Q K+E+ L E +R+ L ++ HEK M+ E + D
Sbjct: 8672 KEKGKLR---QEKQEMDLFRSELQRQREDLETSIQKLTHEKREMEVLRSEIVLEKKDLDQ 8728
Query: 788 EMMHMVLEKDNI------ILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVET 949
+M ++ ++D + I + +I+ + Q + L RD + Q+ +++ E+ + T
Sbjct: 8729 KMKQVIRKRDEMEKIRFDIANARVEIDGERQELEIL----RDNV--QSARQDFERLVERT 8782
Query: 950 IYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSN 1129
+ + + + L LE K ++ +++LK E + + EI +
Sbjct: 8783 ANLEVEESAATDIERLVLEVVKIREMVRNLKGEMERRMEESKVEIDE------------- 8829
Query: 1130 LESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLA---SRIDFLSSECNKLQEQXX 1300
EI+++ + L I Q+R ++ + I++ S ++ + +E + Q++
Sbjct: 8830 ------KEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQE-- 8881
Query: 1301 XXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSK 1480
+ SM K K+ELE+ + I+ E I +++ EL E
Sbjct: 8882 ----------------EESMREILQKEKEELEQLKKDINREKEDI----EISRELVESEI 8921
Query: 1481 SQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHL 1660
+ + + +L+ +T+++ +++ ++V +
Sbjct: 8922 YEGEVKGFTDV-----------------QKYKEELQIVTEELLTKKRNLEQLNSDVQHLM 8964
Query: 1661 DTISSLQTVLSNQKFEIE----KSQKVLQSFESHIEKLVNDS--LHEVDSAFCSLNSRFY 1822
T+ + +K E+E + QK Q E +KL + + E++ +L S
Sbjct: 8965 QTLEEVDIQYIKKKAELEHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINM 9024
Query: 1823 SLIHK---VDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDIL 1993
++ K ++ E LR + + Q Q ++E+E L++ +
Sbjct: 9025 EILQKREDMEKEKENLRREKQETELFRGELQRQ------RDEVESSRQALIMEKDQFKLK 9078
Query: 1994 SWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYF 2173
+R E + + E L+++ DLE +A+ A +SL++ + K
Sbjct: 9079 IDHQRNEMSAAFEKEH--------KRLENMENDLENQRAKLA-ESLNDAAKMEQKLQQMK 9129
Query: 2174 SQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKL 2353
++L +E + E K+ ++ + R+ + +I + H +KK
Sbjct: 9130 NELNKEKEQVEEMKQMVKTERVKIEQEKEEMRKQTQ-----------EIEDGHEKLQKKT 9178
Query: 2354 -LAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELE---LQRKTEEIYDLKRL 2521
+A + A++ L++ + L +Q E E + L R + E+ D K
Sbjct: 9179 EIADKLLQDANSESDRLKDLSMK--LQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIR 9236
Query: 2522 LLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQS 2701
L N+++ + + K E++++E + L + +Q+ + + K ++++
Sbjct: 9237 LKNDRDAYEKD-----------MTHLELKREELVRETEDLERKILQQREQDEMAKRDIEN 9285
Query: 2702 KIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSV 2881
+ ++L E+ + D +L ++ A + H++R+ LL L+ + +E
Sbjct: 9286 QTEAL--EVMKVD----ILKKRNEFAKEMENVHSERQKLLL-----LQGALQSQE----- 9329
Query: 2882 CSDVLTALFVEMVREKEFSLSLATKEQ---------ETVNQKQMSLRKMLEDKDKLLCLV 3034
S++ +F+E +K + A E+ ETV +Q RK++E+ +
Sbjct: 9330 -SELENRVFME--EQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQR----E 9382
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVFLQSE----EREKIEEQKRVLDQALQECEELK 3202
E+ + K QI E+ K++ +N + Q E E+ +E++K L++ E +E++
Sbjct: 9383 KEQLEISKNQI---EQEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQ 9439
Query: 3203 NDIQNKHSDIDS----LREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQ 3370
N I+ + D+++ + E++++ ++ R + + +
Sbjct: 9440 NAIRKEREDLENCWVEIEGEKKRMEEETRRLEMHR------------------EEIKKVD 9481
Query: 3371 LELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKI 3550
EL+ E +++ EK + ++ L++ K E+ +K ++ + ++
Sbjct: 9482 SELQKSRENIESREEKINNKMEELLQMKVEMGRTKEEIEKESQRLQDATID--------- 9532
Query: 3551 LLLESSQSATREQTEKYRDLLN-SLTEEHADLKKQFLSAT----EELQSKERDLEVAMTE 3715
LE++++ + Q +K+ D+++ + E+ ++K Q T EE++ K +DLE+ M +
Sbjct: 9533 --LENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQLDKETKRLSEEIELKVKDLEMEMAD 9590
Query: 3716 TKFLKEKLLVSDENLKEKDLQ 3778
K K++ + + L EK+ Q
Sbjct: 9591 MKRQKQE-IEDTKGLLEKEKQ 9610
Score = 99.8 bits (247), Expect = 9e-18
Identities = 238/1239 (19%), Positives = 502/1239 (40%), Gaps = 68/1239 (5%)
Frame = +2
Query: 302 RKSLETKIAE-TLERMEIHEGDTANTLKNMNFD------------LGQDNPGVPGLLEDI 442
+ LET+I + TLE+ ++ + L+ + D + + + E+I
Sbjct: 8332 KDDLETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANATEEI 8391
Query: 443 RNTKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNK-KIEDLNH 619
+ L+ + + + + + +L + ++EE AA D E +L KI ++
Sbjct: 8392 NRERQELEILRNNVQSARHDFELLLERTANLEDEES----AATDIERLVLEVVKIREMVR 8447
Query: 620 KIWSLEETLQYKEEVILSSHETI-SERDRLLKDFIHEKDLMQQRAQETEQ-KLASRDNEM 793
+ E K +V + E SE R ++D ++ + +E E+ + R+ E
Sbjct: 8448 NLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEK 8507
Query: 794 MHMVL-EKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQ 970
M L EK S+ + + + + + L +DEI + EI +++VE V +
Sbjct: 8508 MRAELAEKQQEQESMREMLHKEREELEQL----KDEINREKEDVEIRRELVEA--VIDKE 8561
Query: 971 ELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQ---AEISKLSHTLEESIMNSNLESL 1141
E+ E D+ KY++E+QS+ +E K+ +++ L T+EE + +
Sbjct: 8562 EMKEFTDI-----QKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKR- 8615
Query: 1142 FTAEIYENTFR-ELGDQISQLRNDMYSKNSYI-DSLASRIDFLSSECNKLQEQXXXXXXX 1315
AE+ F + G+Q+ + + D +N +I + + ++ D L K+ +
Sbjct: 8616 --AELEGIGFELKKGEQLLEKQKDELKENGWIVEEIKNKKDSLE----KINMEILRKNED 8669
Query: 1316 XXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSI 1495
K M++ + EL+ +R E+LE + +QK+ +E E ++ I
Sbjct: 8670 MDKEKGKLRQEKQEMDL----FRSELQRQR----EDLE--TSIQKLTHEKREMEVLRSEI 8719
Query: 1496 XXXXXXXXXXXXXXXXXXXXVVNMAFG------------SKLEELTDQINIFNSVIDKKE 1639
+ + F +LE L D + ++
Sbjct: 8720 VLEKKDLDQKMKQVIRKRDEMEKIRFDIANARVEIDGERQELEILRDNVQSARQDFERL- 8778
Query: 1640 AEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSA--FCSLNS 1813
E + +L+ S T + E+ K ++++++ + +E+ + +S E+D F S
Sbjct: 8779 VERTANLEVEESAATDIERLVLEVVKIREMVRNLKGEMERRMEESKVEIDEKEIFKSEIQ 8838
Query: 1814 RFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLV------LND 1975
R I ++ + L+ ++N + + ++ E + K++ E + +++ L
Sbjct: 8839 RLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQEEESMREILQKEKEELEQ 8898
Query: 1976 FSNDILSWSRRKEEAVVHDDEFDAE----RIALLNELKSLHQDLELLKAEEAVKSLSNNV 2143
DI +R KE+ + + ++E + +++ ++L+++ E K N+
Sbjct: 8899 LKKDI---NREKEDIEISRELVESEIYEGEVKGFTDVQKYKEELQIVTEELLTKK--RNL 8953
Query: 2144 GVSTKGIHYFSQLIQEGKDGEASDVQG-KSRALRRHSTGQAFREPPKPEDLYTTYSEGKI 2320
+ + Q ++E D+Q K +A H T + + E E
Sbjct: 8954 EQLNSDVQHLMQTLEE------VDIQYIKKKAELEHITSEIQKREQILEKQKKKLEENGW 9007
Query: 2321 VEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYEL---ELQRK 2491
+ EE +++ + T ++ + + K + + K++ K+E EL ELQR+
Sbjct: 9008 I----IEEIEMMKV----TLESINMEILQ--KREDMEKEKENLRREKQETELFRGELQRQ 9057
Query: 2492 TEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKM 2671
+E+ ++ L+ EK+ +F+ + QR +M
Sbjct: 9058 RDEVESSRQALIMEKD----------------------QFKLKIDH---------QRNEM 9086
Query: 2672 LCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAG 2851
++E +++++ +++ + + LAE L+DA K Q ++ L K +E
Sbjct: 9087 SAAFEKE-HKRLENMENDLENQRAK---LAESLNDAAKMEQKLQQMKNELNKEKEQVEE- 9141
Query: 2852 ITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCL 3031
++ V++ +EKE + T+E E ++K L+K E DKLL
Sbjct: 9142 ----------MKQMVKTERVKIEQEKE-EMRKQTQEIEDGHEK---LQKKTEIADKLLQD 9187
Query: 3032 VGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEE----L 3199
E+ K L+ +++ E ++E +KR LD+ +E ++ L
Sbjct: 9188 ANSESDRLKDLSMKLQMQRQDIEKT----------NTEMETKKRSLDRMSRELQDDKIRL 9237
Query: 3200 KNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLEL 3379
KND D+ L ++E+L ++ + +L+ L+
Sbjct: 9238 KNDRDAYEKDMTHLELKREELVRE-------------------------TEDLERKILQQ 9272
Query: 3380 RNYNEELKNEIEKKSTDIDLL-----------IKEKEELN---ERLAYTQKAMEQKEAVL 3517
R +E K +IE ++ ++++ KE E ++ ++L Q A++ +E+ L
Sbjct: 9273 REQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQESEL 9332
Query: 3518 VEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDL 3697
++F EQK L + +TE+ R L ++E + ++ EELQ ++ L
Sbjct: 9333 ENRVFMEEQKHL------KQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQREKEQL 9386
Query: 3698 EVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQ 3814
E++ + + K+ L NL E+ L+ E AN E +
Sbjct: 9387 EISKNQIEQEKKDLQNMKSNL-ERQLESLRHEKANVEDE 9424
Score = 99.0 bits (245), Expect = 1e-17
Identities = 237/1220 (19%), Positives = 485/1220 (39%), Gaps = 57/1220 (4%)
Frame = +2
Query: 305 KSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGL 484
K + +IAE L+++ GD +N +L ++ + + + ++ +D+ + L
Sbjct: 1961 KKSQDEIAEQLKQV----GDMMQFTQNEKDNLDRERAAI--IEQKLQMERDMTHLLNREL 2014
Query: 485 YVSNVVSDAVLNGVVSAQE------------EEFKEALAAKDSENFLLNKKIEDLNHKIW 628
+V VLN ++ E+ K L + E L + I + K+
Sbjct: 2015 ESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLE 2074
Query: 629 SLEETLQYKEEVILSSHETISERDRLLKDFIH---EKDLMQQRAQETEQKLASRDNEMMH 799
S+ +TL E + +T++E+ +L + E+D + A+ET++K D + +
Sbjct: 2075 SVLQTLAEDTEKLRI--DTLAEKQKLEDAAVELQKERDEIMNIAEETKRK--REDVDKIR 2130
Query: 800 MVLEKDNIILS-----LHKQIELQSQNTQSLDCFRRD--EIEDQNIKEEIEKQIVETIYV 958
+ +EK I L K+ + Q++ ++D ++D ++ + E+Q ++ + V
Sbjct: 2131 VGIEKQEITFKDLKADLQKEAAIVENQRQAV---QKDIQNVKDMEVQIQKERQYMDRL-V 2186
Query: 959 TQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSK------------------QAEI 1084
+I++ + D +++E K + E++S +DE +E SK QAEI
Sbjct: 2187 EEIEKRTKALDEMQMEVDKERQEVESKRDELE-QETSKLREDEDEFSRQKEKNNIIQAEI 2245
Query: 1085 SKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLR-NDMYSKNSYIDSLASRIDF 1261
K S LE + + N+ E T EL + LR N+ K ID L +++
Sbjct: 2246 QKESDNLE--LQSENISK-------ERTIFELEKEHLGLRENEAEYKQKQIDELQNKLRM 2296
Query: 1262 LSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISK 1441
+ ++Q +K + + + L+++ +E + E E + K
Sbjct: 2297 EKVQVEQMQADKDQQRKKAEY-------VKTARGRETTALEEQ-RQEMESLREEYENVEK 2348
Query: 1442 LQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNS 1621
+K NE E +S+ + E+L Q +F
Sbjct: 2349 QKKHVNEQKELFESRMKSLEMENEAMKKYKEK-----------LDKEYEDLQFQRQLFEK 2397
Query: 1622 VIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFC 1801
I + E+ + I + L QK + +L++ + +EK D L EV
Sbjct: 2398 EIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDEV----- 2452
Query: 1802 SLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFS 1981
+ + + +V+ L +Q + +SQE+ + K+ L+ L N+ +
Sbjct: 2453 --RKKINADLSEVEKQKSAL------VQMNLKISQEESYVKKEKDRLK-----LQENEQN 2499
Query: 1982 NDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQD-LELLKAEEAVKSLSNNVGVSTK 2158
+ + ++ E E + ++ L N + L ++ +E+ K ++ V + N V
Sbjct: 2500 MQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITKEKQRVNEMQNEVKRKNA 2559
Query: 2159 GIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPT 2338
+ Q + +D ++ L R E
Sbjct: 2560 SVDLIKQEVLREQD----HIENSREILNR--------------------------ELEKI 2589
Query: 2339 EEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKR 2518
+EKK + FE D K++++G Q +K E LQ++ E+ +R
Sbjct: 2590 KEKKTILAEEFEALD---------DKKEMIGKEMQRLGKMKAE----LQKEAEDTEKQRR 2636
Query: 2519 LLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQ 2698
+ N++ V ++ + + + + EE L V K+ L+
Sbjct: 2637 DIDNDRRN-----------NEEMVIKLQNEKKDIETSTDRIRDEEAN----LRVQKQRLE 2681
Query: 2699 SKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTS 2878
S D+L KE + + + + L+K Q ES +H L +REI
Sbjct: 2682 SDRDTLEKERFDLEKTKTEMKD-----LEK-----QLESQSRQHEIQLVEIQKEREI--- 2728
Query: 2879 VCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQ--MSLRKMLEDKDKLLCLVGEENKE 3052
L L + + ++KE KE++ +++ +SLR+ LE++ + + +
Sbjct: 2729 -----LEQLKINLSKQKED----LEKERDCFEKEKADISLREELEEQSEKEG-IDKTRVR 2778
Query: 3053 HKRQIAILEKLK----EETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNK 3220
K+++ LE+ + +E ENN + + +ER+KIE+ K L + ++ E+ + DI+N
Sbjct: 2779 IKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIEND 2838
Query: 3221 HSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEEL 3400
+ + + + + K + L+ + +L+ N E+
Sbjct: 2839 RRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEM 2898
Query: 3401 KN-----EIEKKSTDIDLL-IKEKEELNERLAYTQKAMEQKEAVLVEK-LFEGEQKILLL 3559
K+ E + + +I L I+++ E+ E+L T +QKE + E+ FE E+ + L
Sbjct: 2899 KDLEKQLESQNRQHEIQLAEIQKEREILEQLKLT--LSKQKEDLEKERDCFEKEKADISL 2956
Query: 3560 --ESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKE 3733
E + + RE K R + +E +LK+ L+ +EL++ E ++ E +++
Sbjct: 2957 REELQEQSEREGIGKTR---VRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQ 3013
Query: 3734 KLLVSDENLKEKDLQLRAFE 3793
+ ++ + Q R E
Sbjct: 3014 IKAELQKEAEDTEKQRRDIE 3033
Score = 94.4 bits (233), Expect = 4e-16
Identities = 243/1244 (19%), Positives = 500/1244 (40%), Gaps = 68/1244 (5%)
Frame = +2
Query: 293 LDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTV 472
+ T+ + KI+E + + + + +K +DL Q + D+ + + +
Sbjct: 1897 IKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQ-------MQTDLNRQQKEMQDI 1949
Query: 473 ESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQY 652
++ +++ + + +Q+E ++ D F N+K + +E+ LQ
Sbjct: 1950 QNAVFMEK-------SELKKSQDEIAEQLKQVGDMMQFTQNEKDNLDRERAAIIEQKLQM 2002
Query: 653 KEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILS 832
+ ++ + + + K+ ++EK L++ + + +D E M + LE++
Sbjct: 2003 ERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRDM--QDLEQMKINLEREK---- 2056
Query: 833 LHKQIELQSQNTQSLDCFRRDEIED--QNIKEEIEKQIVETIYVTQIQELGEEHDLLRLE 1006
++++LQ Q+ +D++E Q + E+ EK ++T+ + Q+L + +E
Sbjct: 2057 --EEMQLQRQSIAE----EKDKLESVLQTLAEDTEKLRIDTL--AEKQKLEDA----AVE 2104
Query: 1007 SAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLE-ESIMNSNLESLFTAE--IYENTFRE 1177
K +DEI ++ +E K + ++ K+ +E + I +L++ E I EN +
Sbjct: 2105 LQKERDEIMNIAEETKRK----REDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQA 2160
Query: 1178 LGDQISQLRN---DMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTL 1348
+ I +++ + + Y+D L I+ + +++Q +
Sbjct: 2161 VQKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVD---------------- 2204
Query: 1349 KASMEMQCSKLKDELEEERGKISENLERISKLQKMNNEL-AERSKSQNSIXXXXXXXXXX 1525
K E++ + DELE+E K+ E+ + S+ ++ NN + AE K +++
Sbjct: 2205 KERQEVESKR--DELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKE 2262
Query: 1526 XXXXXXXXXXV---VNMA--FGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVL 1690
+ N A +++EL +++ + +++ +A+ ++T
Sbjct: 2263 RTIFELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTAR 2322
Query: 1691 SNQKFEIEKSQKVLQSFESHIE------KLVNDSLHEVDSAFCSL---NSRFYSLIHKVD 1843
+ +E+ ++ ++S E K VN+ +S SL N K+D
Sbjct: 2323 GRETTALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKYKEKLD 2382
Query: 1844 NSGETL----RAFVKNIQNQVAVSQ--EQHIEHQCKE--------ELEGHIADL---VLN 1972
E L + F K IQ Q ++IE + KE E ++ + V+
Sbjct: 2383 KEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVE 2442
Query: 1973 DFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVS 2152
D L R+K A + + E + +N LK ++ + K ++ +K N +
Sbjct: 2443 KSKTDELDEVRKKINADLSEVEKQKSALVQMN-LKISQEESYVKKEKDRLKLQENEQNMQ 2501
Query: 2153 TKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPH 2332
SQL K E + Q + +R + + + E + T + ++ E
Sbjct: 2502 ------MSQL--NAKQNELDERQAEMEKQKREL--ENVMDRLEKEKVEITKEKQRVNEMQ 2551
Query: 2333 PTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKT------ 2494
++K ++ D + +EQ H + S L RE E ++KT
Sbjct: 2552 NEVKRKNASV---------DLIKQEVLREQ--DHIENSREILNRELEKIKEKKTILAEEF 2600
Query: 2495 EEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKML 2674
E + D K ++ E L AE+ + E ++ + + + +M+
Sbjct: 2601 EALDDKKEMIGKEMQRL-----------GKMKAELQKEAEDTEKQRRDIDNDRRNNEEMV 2649
Query: 2675 CVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLS---DALKKSADHAQRESHLLKHIADLE 2845
L+ E + I++ I+++++N +V ++L D L+K ++ +K DLE
Sbjct: 2650 IKLQNE-KKDIETSTDRIRDEEANLRVQKQRLESDRDTLEKERFDLEKTKTEMK---DLE 2705
Query: 2846 AGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLL 3025
+ + R+ E L KE+E + Q +++L K ED +K
Sbjct: 2706 KQLESQS------------------RQHEIQLVEIQKEREILEQLKINLSKQKEDLEKER 2747
Query: 3026 CLVGEENKEHKRQIAILEKLKEETEN---NPGRVFLQSE-------------EREKIEEQ 3157
+E K I++ E+L+E++E + RV ++ E E E E Q
Sbjct: 2748 DCFEKE----KADISLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQ 2803
Query: 3158 KRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXX 3337
K++++ + E++K ++Q + D + R++ E + M
Sbjct: 2804 KQIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRI 2863
Query: 3338 XXISSNLDSMQLELRNYNEELKNE---IEKKSTDIDLLIKEKEELNERLAYTQKAMEQKE 3508
+NL ++ L + + L+ E ++K +T++ L K+ E N R Q A QKE
Sbjct: 2864 RDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQN-RQHEIQLAEIQKE 2922
Query: 3509 AVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKE 3688
++E+L K+ L S +E EK RD +E AD +S EELQ +
Sbjct: 2923 REILEQL-----KLTL-----SKQKEDLEKERDCFE---KEKAD-----ISLREELQEQS 2964
Query: 3689 RDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQYQ 3820
+ T + KE + LK+ L + E+ N+E Q Q
Sbjct: 2965 EREGIGKTRVRIKKEM-----DELKQTRLNV-VKELENNELQKQ 3002
Score = 94.0 bits (232), Expect = 5e-16
Identities = 221/1220 (18%), Positives = 488/1220 (40%), Gaps = 53/1220 (4%)
Frame = +2
Query: 284 DGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLL 463
DG + + ++ E+L + +GD L+ M D + + + + + + L
Sbjct: 10118 DGKRNEINKEQQRLEESLRAINEEKGD----LEIMRADYEKQEQQIEEMRVEAKMERKEL 10173
Query: 464 DTVESGLYVSNVVSD---AVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSL 634
D ++S L D LN + E+E + L SE +++ED
Sbjct: 10174 DQIKSELEKDKTEIDYEWKKLNNDRNMIEKE-RNDLEKMKSELMTQRQQMED-------- 10224
Query: 635 EETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEK 814
+ E+ E +E+D++ K+ K+++++ E E++ + + LE+
Sbjct: 10225 -----ERSELDQKIKEANTEKDKIEKN----KEIVERLMAEVEEQRNDFKLKKEELALER 10275
Query: 815 DNII----LSLHKQIELQSQNTQ----------SLDCFRRDEIEDQNIKEEIEKQIVETI 952
NI+ L + ELQ+++ Q + + E Q K+EI+ I ET
Sbjct: 10276 QNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETS 10335
Query: 953 YVTQ-IQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSN 1129
+ ++++ ++ + E +D ++ ++E + K Q I + + + +
Sbjct: 10336 RQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQ-KEED 10394
Query: 1130 LESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXX 1309
L + E E+ +I +++ ++ I+ + L + K +E+
Sbjct: 10395 LTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAMT 10454
Query: 1310 XXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISK----LQKMNNELA--- 1468
+K+ + + K E++ E+ K++++++ I + L+KM +E+
Sbjct: 10455 IKLKMEREDLDQIKSELVRE----KTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQK 10510
Query: 1469 -ERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAE 1645
E K ++ + V + F ++EE +I + +D + +
Sbjct: 10511 QEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMF--EVEEQRHEIQLQKEELDIERQK 10568
Query: 1646 VSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYS 1825
++ D + ++ L N+ I +V+ K ++L E+++ S
Sbjct: 10569 IADEQDLLIQNKSELQNENERIRNINEVI--------KKERETLKEMEAHLEKEKEEMKS 10620
Query: 1826 LIHKVDNSGETLRAFVKNI--QNQVAVSQEQHIEHQCKEELEGHIADLV--LNDFSNDIL 1993
+ + E L +I QNQ + Q +E + KE++ L +++F +
Sbjct: 10621 ITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQE-KEDINHEWTQLQQRIDEFDAQV- 10678
Query: 1994 SWSRRKEEAVVHDDEFDAERIAL------LNELKSLHQDLELLKAEEAVKSLSNNVGVST 2155
S++KEE + E ER +L + E+K+ +LE +K E+ + + V
Sbjct: 10679 --SKQKEEDLTKQKEMKEERKSLEETKARIIEMKT-KAELEDIKKEKEKEEEEEEMRVKV 10735
Query: 2156 KGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHP 2335
+ DG+ D + KS R S + E K D + KI+E
Sbjct: 10736 E------------MDGKELD-RIKSELKRERS--EIDHEQKKLND------DKKIIEQEK 10774
Query: 2336 TEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLK 2515
+K+ K +++ +Q E EL+ K ++ Y K
Sbjct: 10775 QNLEKM--------------------KSEIMKQRQQM-----EEERSELENKIKQTYIEK 10809
Query: 2516 RLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENK---LLPVEEVQRYKMLCVLK 2686
+ N K EI K ++E K EE+ + +
Sbjct: 10810 CDIENSK-------------------EIVQKLMVEVEEQKHEIQFQKEELDIERQKIADE 10850
Query: 2687 EELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDRE 2866
++L + S L+ E+ N + +K + LK+ H +++ +K +++ + +E
Sbjct: 10851 QDLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRL--KE 10908
Query: 2867 IMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEEN 3046
+ + +DV +++ +++ L +E+E +N K L++ +++ D + E++
Sbjct: 10909 DLEKMSTDV-NKQNKDLMNQRD----LLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQD 10963
Query: 3047 -------KEHKRQI------AILEKLKEETENNPGRVFLQSEEREKIEEQKRVL-DQALQ 3184
KE ++ + I K K E E ++EE E+ EE+ RV+ + +
Sbjct: 10964 LPKEKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERK 11023
Query: 3185 ECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDS 3364
E ++K++++ S+ID EQ+KLN ++ + +
Sbjct: 11024 ELYQIKSELERVRSEID---HEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSE 11080
Query: 3365 MQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQ 3544
+ +++ N E K++IEK ++ L+ E EE + + QKE + +E+ ++
Sbjct: 11081 LDNKIQQTNLE-KHDIEKSKEIVEKLMVEVEEQRKDIQL------QKEELDIERQKIADE 11133
Query: 3545 KILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKF 3724
+ LL++ +++ + + E+ + + + +E L++ + L+ ++ +L + ET+
Sbjct: 11134 QNLLVQ-NKAKLQNENERIKKVDEEIKKERETLREMEI----HLKKEKEELRSIIEETQR 11188
Query: 3725 LKEKLLVSDENLKEKDLQLR 3784
KE L ++ E+ L L+
Sbjct: 11189 RKEDLEKMSTDINEQKLHLK 11208
Score = 91.7 bits (226), Expect = 2e-15
Identities = 261/1407 (18%), Positives = 533/1407 (37%), Gaps = 232/1407 (16%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAET-LERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRN 448
+EVE+ RK ++ + E +ER +I D N L L +N + + E+I+
Sbjct: 11107 VEVEE----QRKDIQLQKEELDIERQKI--ADEQNLLVQNKAKLQNENERIKKVDEEIKK 11160
Query: 449 TKDLLDTVESGLYVSNVVSDAVLNGVVSAQEE------EFKEALAAKDSENFLLNKKIED 610
++ L +E L +++ +E+ + E ++ LL ++ E+
Sbjct: 11161 ERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREE 11220
Query: 611 LNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNE 790
+NH++ L++ + + + E +++++ + K L + +A+ E K + E
Sbjct: 11221 INHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEE----RKSLEETKARIIEMKTKAELQE 11276
Query: 791 MMHMVLEKDNIILSLHKQIELQSQNTQSLDCFR-RDEIEDQNIKEEIEKQIVE------- 946
+M E+D + + ++E + N + R R EI+ + K +K+I+E
Sbjct: 11277 IMQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLE 11336
Query: 947 ---TIYVTQIQELGEE---------------HDL--------------------LRLESA 1012
+ +TQ Q++ EE HD+ +RL+
Sbjct: 11337 KMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKE 11396
Query: 1013 KYQDEIQSLKDEC---------------HAKEMSKQAEISKLSHTLEESIMNSNLESLFT 1147
+ E Q + DE KEM + EI K TL+E + E
Sbjct: 11397 ELDIERQKIADEQGLVVQNKAKLQNENERIKEMDE--EIKKEKETLKEMEAHLRKEKEEM 11454
Query: 1148 AEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXX 1327
+ E T R + + ++ D+ +N L ++ D L E ++ +
Sbjct: 11455 RSVIEETQRRKKEDLEKMSTDVNKQNQ---DLMNQRDLLKQEREEINHKWTQLQQRID-- 11509
Query: 1328 XXXXXTLKASMEMQCSKLKDE-------LEEERGKISENLERISKLQKMNNE---LAERS 1477
+ Q SK K+E +EEER + E +I +++ E+
Sbjct: 11510 ---------EFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKE 11560
Query: 1478 KSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSV---IDKKEAEV 1648
K + + V + ++L D + ++K ++E+
Sbjct: 11561 KEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEI 11620
Query: 1649 SGHLDTISSLQTVLSN-------QKFEIEKSQKVLQSFESHIEKLVND---SLHEVD--- 1789
+ ++ L N ++ +IE S++++Q +E+ D E+D
Sbjct: 11621 MKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIER 11680
Query: 1790 --------------SAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQE--QHIE 1921
+ + N R + ++ ETL+ +++ + + + +
Sbjct: 11681 QKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQ 11740
Query: 1922 HQCKEELEGHIADLVLNDFSNDILSWS---RRKEEAVVHD--------DEFDAERIALLN 2068
+ KE+LE D+ N + D+++ +++ E + H DEFDA+
Sbjct: 11741 RRQKEDLEKMSTDV--NKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQ------ 11792
Query: 2069 ELKSLHQDL-ELLKAEEAVKSLSNN-VGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALR 2242
K +DL + K EE KSL + + + I++ K+ E +V ++
Sbjct: 11793 VSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMK 11852
Query: 2243 RHSTGQA------------FREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADA 2386
+ Q + +D E + +E +E K + E ++
Sbjct: 11853 KEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSEL 11912
Query: 2387 SDSPLRNWPKEQLLGHFKQSFAGL-----KREYELELQRKT-----EEIYDLKRLLLNEK 2536
+ + + ++ + + K+ L ++++E++ Q++ ++I D + LL+ K
Sbjct: 11913 ENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNK 11972
Query: 2537 NGLH------AXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKM--------L 2674
+ L + E+ EK +E K + EE +R K +
Sbjct: 11973 SELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSI-TEETRRQKEDLEKMSTHI 12031
Query: 2675 CVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGI 2854
K++L+S+ D L +E +E + K L +++ + + + Q+E L K E
Sbjct: 12032 NEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSK--QKEEDLPKEKEMKEDRK 12089
Query: 2855 TDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLV 3034
+ E ++ A E+ +EKE +EQE + +M +++ + K +L +
Sbjct: 12090 SLEETKANILEMKTKAEPEEIKKEKEKE----EEEQEMRVKVEMERKEIEQIKSQLERVR 12145
Query: 3035 GEENKEHKR---QIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKN 3205
E + E K+ ++E+ KE+ E + Q R+++EE++ LD+ +++ + K+
Sbjct: 12146 SEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQ---RQQMEEERSELDKKIKQTDLEKH 12202
Query: 3206 DIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXIS------------ 3349
DI+N ++ L E EK +++
Sbjct: 12203 DIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQQNENERIKE 12262
Query: 3350 ---------SNLDSMQLELRNYNEEL----------KNEIEKKSTDI-----------DL 3439
L M++ L+ EE+ K ++EK STDI DL
Sbjct: 12263 MDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDL 12322
Query: 3440 LIKEKEELNERLAYTQKAMEQKEAV----------------------------LVEKLFE 3535
L +E+EE+N +L Q+ +++ E ++E+
Sbjct: 12323 LKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNR 12382
Query: 3536 GEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTE 3715
++ +E QS + E +DLL +E D +K+ EELQ + DLE+ M E
Sbjct: 12383 KRTELEEIEVDQSQQNKNVETMKDLLE---KERKDTEKE----REELQKQADDLEMQMIE 12435
Query: 3716 TKFLKEKLLVSDENLKEKDLQLRAFEI 3796
KE++ + ++K L+ +A EI
Sbjct: 12436 HGD-KEEMSKRSLDEEKKLLEQKANEI 12461
Score = 90.5 bits (223), Expect = 5e-15
Identities = 236/1241 (19%), Positives = 467/1241 (37%), Gaps = 149/1241 (12%)
Frame = +2
Query: 539 EEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISER-DRLLKD 715
+ E ++ + +LN + ++LN +LE+ KEE L S R + LL+D
Sbjct: 12986 QAELQKGQLEMEMHQLMLNSERDELNGMRVNLEKQ---KEEFELMQQNLESRRPESLLED 13042
Query: 716 FIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQ----SLDC 883
+ EK +++ A + ++ N M + + I KQIE + + Q L+
Sbjct: 13043 ILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKI-----KQIEGEIKTKQIEMACLEE 13097
Query: 884 FRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSL-----KDE 1048
++ E+++Q E E Q ++Q EE ++ E +DEIQ L K++
Sbjct: 13098 LKQKELDEQKNMRECENQ--------ELQMRREELAKMKTEIDIERDEIQKLRKQYEKEK 13149
Query: 1049 CHAKEMS---KQAEISKLSHTLEESIMNSNLESL---------FTAEIYENTFRE---LG 1183
C +++ ++ E K+ ++ ++ ++SL A++ +N RE +
Sbjct: 13150 CELEQIKPDLQKREPEKIDAEVQHDEIHGGIDSLKEEREEIEKMKADL-QNKLREAENMR 13208
Query: 1184 DQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTL----- 1348
D + + ++++ K + I+ +A + S+ N LQ++ L
Sbjct: 13209 DIMKREKDELEKKEAEIEQMAVETEDNDSDKN-LQDEMMKIEAILKVTKKQKNYLEQMNE 13267
Query: 1349 -----KASMEMQCSKLKDELEEERGKISENLE-RISKLQKMNNELAERSKSQNSIXXXXX 1510
K +E C L+ E E K+ E E +SK++ ER + +I
Sbjct: 13268 NLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKME-------EREAERKTIERVMD 13320
Query: 1511 XXXXXXXXXXXXXXXVVNMAFGSK-----LEELTDQINIFNSVIDKKEAEVSGHLDTISS 1675
+VNM K LEE +++ S + + +E+ +
Sbjct: 13321 EMAEEHEKIKKEREELVNMEEEIKKQRRVLEESMNEMTKKKSELQHERSELYKQKQQLED 13380
Query: 1676 LQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGE 1855
+ + S K +++ + + I K + + ++ + +++ E
Sbjct: 13381 M--IASESKRDVDTERSRQDKEDEQILKREREEIADMKDQLLKEKEDVETTKERINREKE 13438
Query: 1856 TLRAFVKNIQNQVAVSQEQHIEHQ----CKEELEGHIADLVLNDFSNDILSWSRRKEEAV 2023
+ + +Q +E +E+Q K E++ + L D L R A+
Sbjct: 13439 HIEKMQSQLNDQ---KEEMDLENQKLLYMKTEIQ--VKTNALEKMMQD-LQKERENVNAL 13492
Query: 2024 VHDDEFDAERIALL---NELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEG 2194
V + + E+ +L N+ K H + E+ + E ++S+ + + I + ++
Sbjct: 13493 VIQHQKEREQRDILIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTR 13552
Query: 2195 KDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFE 2374
+ E ++ K + + RE E + E K E EK + +
Sbjct: 13553 SE-ELENLIKKQQKEFETKENEMQRERKALEKMNAEL-ERKSTELKNKIEKVTVWEADLQ 13610
Query: 2375 TADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKT-----EEIYDLKRLLLNEKN 2539
L+N + + +++ ++++E+E RKT E + L+ L +EK
Sbjct: 13611 KEKNKTEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKK 13670
Query: 2540 GLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLL 2719
+ + EI + E + +E K L + + L ++ L
Sbjct: 13671 SMLSRLSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKL 13730
Query: 2720 KEIKEKDSNSKVLA------EKLSDALKKSA--------------DHAQRESHLLKHIAD 2839
+EKDS ++ A EKL + ++K+ D ++E L AD
Sbjct: 13731 SIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRAD 13790
Query: 2840 LEAGI-----------TDREIMTSVCSD---------------------------VLTAL 2905
+E T++EI+ ++ L +
Sbjct: 13791 IERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEKQRKRNDLTLQELRKEKMALEQM 13850
Query: 2906 FVEMVREKEFSLSLATK---EQETVNQKQMSLRKMLEDKDKL-LCLVGEENKEHKRQ--- 3064
++ +EK+ SL + +Q + K+ L + ++ D L + L +N +K+Q
Sbjct: 13851 ITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEV 13910
Query: 3065 -IAILEKLKEETENNPGRVFLQSEERE------KIEEQKRVLD-------QALQECEELK 3202
+ I+E +K + + L E R+ E+QK VL Q E E+
Sbjct: 13911 DVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFT 13970
Query: 3203 NDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELR 3382
DI+ + ++ REE + LNK++ L S+ LE+
Sbjct: 13971 TDIKTEKEHVEKEREEIDVLNKEI---------------------IKSKEELQSLNLEI- 14008
Query: 3383 NYNEELKNEIEKKSTDIDLLIKEKEEL------NERLAYTQKAM------EQKEAVLVEK 3526
E K EI K I+ L + + +L + L T+K M ++ E L
Sbjct: 14009 ---EMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMN 14065
Query: 3527 LFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVA 3706
L + + ++ L ++ A + Q E + +L+ +E D+ S + L+ ++ +L
Sbjct: 14066 LQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKL 14125
Query: 3707 MTETKFLKEKLLVSDENL-----KEKDLQLRAFEIANSEKQ 3814
+ L EK+ E L KE+D +I SEKQ
Sbjct: 14126 ---SHVLNEKVQREQEELERLLEKERDDIENCKKIIESEKQ 14163
Score = 87.8 bits (216), Expect = 3e-14
Identities = 268/1329 (20%), Positives = 516/1329 (38%), Gaps = 159/1329 (11%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNT 451
+EVE+ D R E +ER +I D + L +N + + E+I+
Sbjct: 11660 VEVEEQRKDIRLQKEEL---DIERQKI--ADEQGLVVQNKAKLQNENERIKEMDEEIKKE 11714
Query: 452 KDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENF-------LLNKKIED 610
K+ L +E+ L +V+ Q+E+ ++ + +N LL ++ E+
Sbjct: 11715 KETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREE 11774
Query: 611 LNHKIWSLEETL--------QYKEEVILSSHETISERDRLLKDFI--------------- 721
+NHK L++ + + KEE + + ER L + I
Sbjct: 11775 INHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIK 11834
Query: 722 -----HEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCF 886
E+++M+ + + +++L +++ + E D+ L+ ++ Q + L+
Sbjct: 11835 KEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKM 11894
Query: 887 R-------------RDEIED------------QNIKEEIEKQIVETIYVT-QIQELGEEH 988
+ R E+E+ +N KE ++K +VE +IQ EE
Sbjct: 11895 KSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEEL 11954
Query: 989 DLLRLESAKYQDEIQSLKDEC-HAKEMSKQAE--ISKLSHTLEESIMNSNLESLFTAEIY 1159
D+ R + A QD + K E + E K I K TL+E E I
Sbjct: 11955 DIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSIT 12014
Query: 1160 ENTFRELGD------QISQLRNDMYSKNSYIDS-----------LASRIDFLSSECNKLQ 1288
E T R+ D I++ + D+ S+ ++ L RID ++ +K +
Sbjct: 12015 EETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQK 12074
Query: 1289 EQXXXXXXXXXXXXXXXXTLKAS-MEMQCSKLKDELEEERGKISENLERISKLQKMNNEL 1465
E+ KA+ +EM+ +E+++E+ K E E K++ E+
Sbjct: 12075 EEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEI 12134
Query: 1466 AERSKSQ-----NSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVID 1630
E+ KSQ + + + M S++ + Q+ S +D
Sbjct: 12135 -EQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMK--SEIMKQRQQMEEERSELD 12191
Query: 1631 KK-------EAEVSGHLDTISSLQTVLSNQKFEIEKSQKVL----QSFESHIEKLVNDSL 1777
KK + ++ + + L + QK EI+ ++ L Q + L+ + +
Sbjct: 12192 KKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKI 12251
Query: 1778 HEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIA 1957
+ + N R + ++ ETL+ N+Q + KEE+E I
Sbjct: 12252 EQQNE-----NERIKEMDEEIKKERETLKEMEVNLQKE-------------KEEIESVIE 12293
Query: 1958 DLV-----LNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAV 2122
+ L S DI + +K++ + D ER + ++L L Q ++ +
Sbjct: 12294 ETQRRKEDLEKMSTDI---NEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFET---- 12346
Query: 2123 KSLSNNVGVSTK---GIHYFSQLIQEGKDGEA--SDVQGKSRALRRHSTGQAFREPPKPE 2287
++N+ V+TK +L Q K+ E+ + K L Q+ +
Sbjct: 12347 ---TSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTELEEIEVDQSQQNKNVET 12403
Query: 2288 DLYTTYSEGKIVEPHPTEEKKL---LAILAFETADASDSPLRNWPKEQLLGHFKQSFA-- 2452
E K E E +K L + E D + R+ +E+ L K +
Sbjct: 12404 MKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILR 12463
Query: 2453 ---GLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVL 2623
L++E E ++ +K E+ L++ + N+KN + + E +K L
Sbjct: 12464 QRDDLEKEKE-DMMKKWNELDGLQKEIQNQKNEMEEIKCELETKRIEIIKE-----QKRL 12517
Query: 2624 QENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIK-EKDSNSKVLAEKLSDALKKSADH 2800
+E+ EE Q +++ V E+ Q +I+ + + K E+D +++A+ L D
Sbjct: 12518 EESLNTVNEERQYLEIVRVDYEKHQQQIEEMRVKTKMERDELDQLMAKMLMD-------- 12569
Query: 2801 AQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQK 2980
++E+ K D++ L EM + K F+L +E + QK
Sbjct: 12570 -RKENERSK--------------------DMIGLLKKEMEQTK-FNLDAQEEELKLEKQK 12607
Query: 2981 QMSLRKMLEDKDKLLCLVGEENKEHKRQ-----IAILEKLKEETENNPGRVFLQSE---- 3133
+ +K LE + E K K Q E LKEE + PG+ F+Q +
Sbjct: 12608 IQNEKKDLEMFKAEIKREASEVKTLKEQQLEKDTKAFEALKEE--HLPGQ-FVQQKGGEF 12664
Query: 3134 EREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSL-----REEQEKLNKQLRCMXXXXX 3298
ER +I+E KR+L + +E +EL+ + Q ++L ++ E+L+ L
Sbjct: 12665 ERIQIDEVKRILSEIHKEKKELERNKQILEHQREALLEIKSKQPSERLDVILVSSATQTS 12724
Query: 3299 XXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLA 3478
+ + D ++ + +E + EI+K D +K E + ++A
Sbjct: 12725 DLEDIPDVSASQGETVEKHTDIIKEYTTSIPKE-EYEIDKLKQQGDKKLKSTRE-DTKMA 12782
Query: 3479 YTQKAMEQK---EAVLVEKLFEGE--------------QKILLLESSQSATREQTEKYRD 3607
T+ + K + ++ KL G+ +++ + + + + +++ EK R
Sbjct: 12783 DTEVTTQYKYIPDPSIMMKLESGKDETDGLTEVHTTERRELEITKLALQSEQQEIEKIRQ 12842
Query: 3608 LL----NSLTEEHADLKKQF-------LSATEELQSKERDLEVAMTETKFLKEKLLVSDE 3754
+ N L + +DL+KQ+ + E E DLE + ETK +E+L +
Sbjct: 12843 DIDREKNDLEKYRSDLEKQYEEMEICKQNIENERAELEIDLENIIIETKSKQERLESIEV 12902
Query: 3755 NLKEKDLQL 3781
L+EK++Q+
Sbjct: 12903 QLQEKNVQM 12911
Score = 85.1 bits (209), Expect = 2e-13
Identities = 232/1247 (18%), Positives = 476/1247 (38%), Gaps = 81/1247 (6%)
Frame = +2
Query: 266 SFIEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIR 445
S I+V+ ++ + K + +E+M+ D N L+ D+ + + D++
Sbjct: 279 SAIQVQINEIEMKIGETQKAKDLMEQMKAEIEDEKNELEKKKEDIKRQRDQFEQIKLDLQ 338
Query: 446 NTKDLLD-----TVESGLY------------------VSNVVSDAVLNGVVSAQEEEFKE 556
K ++ T + GL + V + N S QE
Sbjct: 339 QVKMEMEQRWHETEKEGLEQRAVIQREKEQLKYLQDEIQRVREEVERNREFSKQEHARIS 398
Query: 557 ALAAKD-SENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEKD 733
L A+ EN L+ K D+ K LEE K E+ ER R ++ + +
Sbjct: 399 QLRAQALEENNLIENKWHDILRKEKDLEEM---KHEI---------ERGR--EELVMNGE 444
Query: 734 LMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQN 913
L+++ ++ EQ + M+ M D I + ++++ + D + + + +
Sbjct: 445 LVKKEWEKIEQAKVDIQSHMISMEGRVDEIKRETERLKHIKTEMQRDKDALEKQKDDTRK 504
Query: 914 IKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKL 1093
KEE E++ E VT+ E R E + E+Q + D AK + ++ E ++
Sbjct: 505 AKEEAERKRYEI--VTEELEHRARLQRERDELENIRAEMQRVNDVEKAKILKEKEESIRI 562
Query: 1094 SHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSE 1273
EE+ L AEI R Q LR + ++L ++ + +S+
Sbjct: 563 R---EEARQERETTELVNAEIKAEKERLNQRQEEMLRERQEIERIKHETLRAKEEIENSQ 619
Query: 1274 CNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSK-----LKDELEEERGKISENLERIS 1438
++E K E+Q +K K ELEEER E+LER
Sbjct: 620 DVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKEQMEEAKVELEEER----EDLER-- 673
Query: 1439 KLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEEL-TDQINIF 1615
K ++ E+ + +N I V S+ E T+++ +
Sbjct: 674 KRDLVSREIEQAEFLRNEILR-------------------VKEEMESRWRETETEEVEL- 713
Query: 1616 NSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSA 1795
A+ L+ + L+ + IE+S+ L ++ ++KL + +
Sbjct: 714 -------RAKTQHELERLEKLREETERSQKNIEESKIELMLWKESLDKLKGEMEEDKHVV 766
Query: 1796 FCSLNSRFYSLIHKVDNSGETLRAFVKNIQ---NQVAVSQEQHIE-----HQCKEELEGH 1951
+N + E L ++ ++ ++ +S+E+ E ++ + EL+
Sbjct: 767 IMQMN--------EAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQ 818
Query: 1952 IADLVLNDFSNDILSWSRRKEEA-----VVHDDEFDAERIALLNELKSLHQDLELLKAEE 2116
A++ D+ + ++ KEEA VH+ E ++ +E + E L+ +
Sbjct: 819 HAEM--EDWFRVV---NKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRD 873
Query: 2117 AVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLY 2296
++ + + K I Q +++ + E +Q + L + F E + E L
Sbjct: 874 EIQKKAEELEQINKEIQRARQELEKMRYFEKESLQ---KMLEDTQQERVFVEQVRSELLK 930
Query: 2297 TTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYEL 2476
+ K + +E K+L + + D R + E + +QS
Sbjct: 931 NKADQDKCLFEMDSERKELEQMRFQVENEKKDLEQRRY--EMMRYDVEQS---------A 979
Query: 2477 ELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEV 2656
++QR+ EE+ +K L+ + ++ I E+ NK L E
Sbjct: 980 QVQRQKEELEKIKSQLVIDTESMNRSRELARQDREKAELLIVEIQEQREDVNKRLE-ETK 1038
Query: 2657 QRYKMLCVLKEELQSKIDSLLK-------------EIKEKDSNSKVLAEKLSDALKKSAD 2797
QR + L +L+++++++ + L K E+KE+ + + E+L D +K D
Sbjct: 1039 QREEALRLLRKDMENEREDLEKIRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKG-D 1097
Query: 2798 HAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKE---FSLSLATKEQET 2968
+RE + H + E I E M ++ + VE+ ++KE + A E
Sbjct: 1098 QEEREK--INH--EKEEMIRKMEAMKREMGEI-EDMKVELTKQKENIDMKMEHARLEMTN 1152
Query: 2969 VNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKI 3148
+ + L + ED + + E ++ + + K KE+ E ++ L E EK+
Sbjct: 1153 LEMMKADLLRQKEDIENQMLAAKSERQQMEVMRTEILKQKEDVER---KMELAKAEMEKM 1209
Query: 3149 EEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXX 3328
+ K + + +E EE + + +++ ++ E E K+L
Sbjct: 1210 QHVKDEIQKQRKELEERMQKTKREIGEMELMKREMEGKKKELDQRMKLTMRKKEEMERLK 1269
Query: 3329 XXXXXISSNLDSMQLELRNYN---EELKNEIEKKSTDIDLLIKE------KEELNERLAY 3481
+++ ++E E++K EI++ + +L ++E KE++N +
Sbjct: 1270 MEIQRAKDDMEFKRVETERQKYEMEQVKAEIQRAREEFELRVEERDLEEEKEQMNLTIIN 1329
Query: 3482 TQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEK-------------YRDLLNSL 3622
+ +E ++ + F+ E + + SQ T +Q E R++L L
Sbjct: 1330 LIQQIEATREMVHKTKFQFENR---MAGSQMGTADQEEMNAEMQRLILEIEHIREMLRGL 1386
Query: 3623 TEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLK 3763
E K+ EE++ + +++ E ++ +EK++ + L+
Sbjct: 1387 KGEVEQNKEIMKRDREEIRLLKIEVQRRRREIEYREEKIMREQDELE 1433
Score = 84.0 bits (206), Expect = 5e-13
Identities = 228/1214 (18%), Positives = 473/1214 (38%), Gaps = 129/1214 (10%)
Frame = +2
Query: 527 VSAQEEEFKEALAAKDSENFLLNKKIEDLNHK---IWSLEETLQYKE---------EVIL 670
+ ++E+ ++ L A +EN LN++ + L+ K + S + L+YK+ +V
Sbjct: 1591 LQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSEKSKLEYKKPLEIKQVDAQVQT 1650
Query: 671 SSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASR----DNEMMHMVLEKDNIIL--- 829
E SE D L I E D +Q + +Q+L ++ + +M + L +D + L
Sbjct: 1651 ELMEDASEYDMALS--IEELDKQRQFLEYFKQELLAQKCTMERQMAEIELSRDELSLREA 1708
Query: 830 ----------SLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELG 979
+ Q+ELQ Q + +DE+E K E++K V+ TQI E
Sbjct: 1709 TLQTATQTTADMELQLELQKQELEQT----KDEME--RTKLEVQKGWVDL--QTQIAESR 1760
Query: 980 EEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAE-- 1153
E+ +++R+E K +D + ++ + ++ + +A+ L TL + N + +
Sbjct: 1761 EKEEMVRIELEKARDVLNRIRQDVETEKQTMEAD---LKFTLAKEFENLEAQRKMMEDEK 1817
Query: 1154 -IYENTFRELGDQ---ISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXX 1321
EN EL + I + +++M+ + +++ A ++ E K +
Sbjct: 1818 RALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERS 1877
Query: 1322 XXXXXXXTLKASMEMQCSKLK-----------------DELEEERGKISENLERISKLQK 1450
L+ E+ +++K DE+E E+ KI + ++Q
Sbjct: 1878 REIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQT 1937
Query: 1451 -MNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMA-----------------FG 1576
+N + E QN++ V +M
Sbjct: 1938 DLNRQQKEMQDIQNAVFMEKSELKKSQDEIAEQLKQVGDMMQFTQNEKDNLDRERAAIIE 1997
Query: 1577 SKLEELTDQINIFNSVID-----KKEA------------EVSGHLDTISSLQTVLSNQKF 1705
KL+ D ++ N ++ KKE + + + ++ L +K
Sbjct: 1998 QKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKE 2057
Query: 1706 EIE-----------KSQKVLQSFESHIEKLVNDSLHE---VDSAFCSL---NSRFYSLIH 1834
E++ K + VLQ+ EKL D+L E ++ A L ++
Sbjct: 2058 EMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAE 2117
Query: 1835 KVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSN--DILSWSRR 2008
+ E + I+ Q ++ + Q + + + V D N D+ ++
Sbjct: 2118 ETKRKREDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQK 2177
Query: 2009 KEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQ--- 2179
+ + + E +R L+E++ + D E + E L + FS+
Sbjct: 2178 ERQYMDRLVEEIEKRTKALDEMQ-MEVDKERQEVESKRDELEQETSKLREDEDEFSRQKE 2236
Query: 2180 ---LIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKK 2350
+IQ E+ +++ +S + + T F + L +E K + + K
Sbjct: 2237 KNNIIQAEIQKESDNLELQSENISKERT--IFELEKEHLGLRENEAEYKQKQIDELQNKL 2294
Query: 2351 LLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLN 2530
+ + E A R + +++ A ++ E+E R+ E + ++ +N
Sbjct: 2295 RMEKVQVEQMQADKDQQRKKAEYVKTARGRETTALEEQRQEMESLREEYENVEKQKKHVN 2354
Query: 2531 EKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYK-MLCVLKEELQSKI 2707
E+ L + + + EN E +++YK L E+LQ +
Sbjct: 2355 EQKEL-----------------FESRMKSLEMEN-----EAMKKYKEKLDKEYEDLQFQR 2392
Query: 2708 DSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDR-------E 2866
KEI++ + ++ AE + + KK + + + ++ + + + ++ E
Sbjct: 2393 QLFEKEIQQMRTELQIEAENI-ERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDE 2451
Query: 2867 IMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLC--LVGE 3040
+ + +D+ VE + ++L ++E+ +K+ K+ E++ + L +
Sbjct: 2452 VRKKINADLSE---VEKQKSALVQMNLKISQEESYVKKEKDRLKLQENEQNMQMSQLNAK 2508
Query: 3041 ENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNK 3220
+N+ +RQ A +EK K E EN R+ E+EK+E + + Q E++N+++ K
Sbjct: 2509 QNELDERQ-AEMEKQKRELENVMDRL-----EKEKVE-----ITKEKQRVNEMQNEVKRK 2557
Query: 3221 HSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEE- 3397
++ +D ++ QE L +Q I ++ + + EL E+
Sbjct: 2558 NASVDLIK--QEVLREQ----------------------DHIENSREILNRELEKIKEKK 2593
Query: 3398 --LKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAV---LVEKLFEGEQKILLLE 3562
L E E +++ KE + L + A QK E E + E+ ++ L+
Sbjct: 2594 TILAEEFEALDDKKEMIGKEMQRLGKMKAELQKEAEDTEKQRRDIDNDRRNNEEMVIKLQ 2653
Query: 3563 SSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKER-DLEVAMTETKFLKEKL 3739
+ + T++ RD E + ++KQ L + + KER DLE TE K L+++L
Sbjct: 2654 NEKKDIETSTDRIRD-----EEANLRVQKQRLESDRDTLEKERFDLEKTKTEMKDLEKQL 2708
Query: 3740 LVSDENLKEKDLQL 3781
+ ++ ++QL
Sbjct: 2709 ---ESQSRQHEIQL 2719
Score = 83.2 bits (204), Expect = 8e-13
Identities = 212/1227 (17%), Positives = 466/1227 (37%), Gaps = 63/1227 (5%)
Frame = +2
Query: 320 KIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGLYVSNV 499
+I L+ + DT N + +L +D + ++++ +++ + + L +
Sbjct: 7547 QIRAELQNKQRDMDDTTNIMMKEKAELARDLENLQNEKDELQKSRENIQKLMKELQEERL 7606
Query: 500 VSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSH 679
+ LN + ++F E + K N ++++ +I + L +E+I
Sbjct: 7607 KTSEALN----KERQQFTEEIKLK-------NDSLDEIQAEIDRQKRALVTDKEIITKQM 7655
Query: 680 ETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMV--LEKD-NIILSLHKQIE 850
+ + + + E D+ + Q + L E++ LE++ + +L + +E
Sbjct: 7656 MDLQKTQDVRRQS-DESDIARANLQRERESLDQLSVEILKQKQDLERERDELLEQWRLVE 7714
Query: 851 LQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEI 1030
Q + +++ + + ++++ E+I KQ+ + + +L +L L K
Sbjct: 7715 TQKMDNENVKQLKTELLDEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNLQK----- 7769
Query: 1031 QSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRND 1210
Q ++DE +A++ ++ L+ + ++E +YE + ++ +++
Sbjct: 7770 QGIQDE--------RAQLERMKGELQ--MKADDIERKMQEILYEK------QKYAERKSE 7813
Query: 1211 MYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDE 1390
Y +Y+D + + L+ E + E K +E+ ++ + E
Sbjct: 7814 NYKIQTYLDEANAEVQKLNKELERYDENLE----------------KCKLELDKARAETE 7857
Query: 1391 LEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMA 1570
++ KI E + LQK + +
Sbjct: 7858 RVKQGAKIPETQQIEQSLQKERDYI----------------------------------- 7882
Query: 1571 FGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESH 1750
E++ + I+K +AE+ + +Q + QK E+ K QK+ E
Sbjct: 7883 -----EDIRRNLFKKEEAIEKDKAEIRLRHQELDLIQAKVVKQKEEMVK-QKIESEREIQ 7936
Query: 1751 IEKL-VNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQ 1927
EK + S E++ + L D + + R V N QVA +
Sbjct: 7937 QEKKKLQRSEEELEDKMQKIKREMIELKLLQDET-DGKRKDVDNKMRQVA---------R 7986
Query: 1928 CKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLK 2107
++ELE AD+ + S + +++ + + ERI ++ + H
Sbjct: 7987 KRDELEKMKADV-------ESASKKLEVDRVMLNTERDELERIKTESQRATEHMQSH--- 8036
Query: 2108 AEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPE 2287
AEE L V+T+ +LIQE + K R + E
Sbjct: 8037 AEERAGDLGEKEPVNTR----IQRLIQEAEKASKMAWSTKHEPEMRMQREVSVEEESVER 8092
Query: 2288 DLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKRE 2467
+ + I+E E + A S L N E L K++ +
Sbjct: 8093 QDMSANMQRMILEIEHARETLRGMKDEVQAARKERSELENMKLEFLT--MKKNMEKTYEQ 8150
Query: 2468 YELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPV 2647
E+Q++ ++I K LL E+N L + +K+L EN+LL
Sbjct: 8151 QNDEIQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMALDK----QKLLAENELLER 8206
Query: 2648 EEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLK 2827
E+ K++ E L+S + +E A + + A ++ ++ ++ L
Sbjct: 8207 EKADVIKII----ENLESLREEATRE----------RATETAQATRRDSEELMQKMEALS 8252
Query: 2828 HIADLEAGITDREIMTSVCSDVLTALFVEMVREK-EFSLSLATKEQETVNQKQMSLRKML 3004
+ D + ++ + D L L ++++++ E + A +Q+ + ++ +
Sbjct: 8253 -MEDFQEASKNQMVELKRQIDKLIELKADLLQQQTELKKTKADLKQQMDDLEKTRSEILK 8311
Query: 3005 EDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEE----REKIEEQKRVLD 3172
+KD ++K + ++ +++ K++ E ++ L+ + R +I +K+ LD
Sbjct: 8312 HEKDT-------DSKTRELELIEIQRQKDDLETRIQKLTLEKRDLEVLRSEIVLEKKDLD 8364
Query: 3173 QALQ-------ECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXX 3331
Q ++ E E++++DI N +I+ R+E E L ++
Sbjct: 8365 QKMKQVIRKRDEMEKIRSDIANATEEINRERQELEILRNNVQ-SARHDFELLLERTANLE 8423
Query: 3332 XXXXISSNLDSMQLE-------LRNYNEELKNEIEKKSTDIDLLIKEKEELN-------- 3466
+++++ + LE +RN E++ +EK +ID K E+
Sbjct: 8424 DEESAATDIERLVLEVVKIREMVRNLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDIGQ 8483
Query: 3467 ------------ERLAYTQKAMEQKEAVLVEKLFEGE----------QKILLLESSQSAT 3580
E+ ++ +E+ A L EK E E +++ L+ +
Sbjct: 8484 IRENLGGLGEEIEKTRRDKRELEKMRAELAEKQQEQESMREMLHKEREELEQLKDEINRE 8543
Query: 3581 REQTEKYRDLLNSLTE-----EHADL---KKQFLSATEELQSKERDLEVAMTETKFLKEK 3736
+E E R+L+ ++ + E D+ K++ S TEEL +K+RDL+ ++ + L++
Sbjct: 8544 KEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQT 8603
Query: 3737 L--LVSDENLKEKDLQLRAFEIANSEK 3811
+ + K +L+ FE+ E+
Sbjct: 8604 IEEINIQHGKKRAELEGIGFELKKGEQ 8630
Score = 73.9 bits (180), Expect = 5e-10
Identities = 215/1271 (16%), Positives = 497/1271 (39%), Gaps = 103/1271 (8%)
Frame = +2
Query: 296 DTRKSLETKI---AETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLD 466
+ K ++T + A+ +E++++ ++ + ++ + L+E+I+ +D++D
Sbjct: 6890 EAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIKKKRDIID 6949
Query: 467 TVESGLYVSNVVSDAVLNGVVSAQEEEFKE------ALAAKDSENFLLNKKIEDLNHKIW 628
+ + ++ + + A+ + FK+ ALA + L K ++++
Sbjct: 6950 ESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQQKRNALEKMSKEISRDRM 7009
Query: 629 SLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVL 808
LE+ K+E+ L+ E +R+ D QR QE + L S +
Sbjct: 7010 KLEDE---KKEIQLAREEL----ERMHGDM--------QRQQEAKDHLLSG--------I 7046
Query: 809 EKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEH 988
++++ +I LQ R+ EI D + + ++V Q+ E+ +
Sbjct: 7047 TDESLLKKSEAEIVLQPSQVDKAKPARKTEISDSD---------KQPVFVQQMPEM-DLK 7096
Query: 989 DLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESL--FTAEIYE 1162
D L+ + + ++ +KD + K LE+ ++ ++ L AE+ +
Sbjct: 7097 DALKKDFESEKLDLPKVKDVLPQDQQMK----------LEQKLIEDEMDKLKQMRAELQK 7146
Query: 1163 NTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXX 1342
DQI + + DM ++ +D +A+R+ +L E+
Sbjct: 7147 EA-----DQIEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINIQ------------ 7189
Query: 1343 TLKASMEMQCSKLKDELEEERGKISENLERI-SKLQKMNNELAERSKSQNSIXXXXXXXX 1519
K + + Q + + E + ERI +++ + N ELA++ +
Sbjct: 7190 --KVNQQKQATAFQME--------KTDFERIKTEIDQANKELADQQE------------- 7226
Query: 1520 XXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQ 1699
K ++ ++ +++ A +S ++TI++ LS++
Sbjct: 7227 --------------------KNKKTITEMQKERETLEEMRANISKQVETITNENKSLSSR 7266
Query: 1700 KFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYS---LIHKVDNSGETLRAF 1870
+ E+ K Q+ + + +++L N + E+ C L+ R L +VD+ + +
Sbjct: 7267 ESELAKLQEDILQQQQEMDELKNTIMMEM----CQLDQRQSDIDLLQKEVDDLMDFTKTE 7322
Query: 1871 VKNIQNQ--VAVSQEQHIEHQCKE-ELEGHIAD---LVLNDFSNDILSWSRRKEEAVVHD 2032
+ N++ + ++Q ++I+ ++E + L LN+ D++ + +E +
Sbjct: 7323 MANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNE-EKDLIE--KERELLTKNL 7379
Query: 2033 DEFDAERIALLNELKSLHQDLELLKAEEA-VKSLSNNVGVSTKGIHYFSQLIQEGK---- 2197
D D +++ + EL++L + E +K E+ ++ + ++ G FS+ ++ +
Sbjct: 7380 DHTDKDKMDMKRELENLKVEKETIKNEKKELEKMKISLQRKAIGFKEFSEKTKDERPIVE 7439
Query: 2198 ----------DGEASDVQGKSRALRRHSTGQAFREPPKPEDLYT-------------TYS 2308
D +GK R T + R+ EDL+ Y
Sbjct: 7440 EMAAQFTRQLDISERPAEGKFIEERLDQTEKKRRKTYYTEDLFQEEKTDLQKTKEEINYD 7499
Query: 2309 EGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQR 2488
+I K+ + T++ + KE++ + + + ELQ
Sbjct: 7500 REEIYRQRTELNKEKETLKQMHTSNLKEIENIEKEKEKIQRTWNEL-----DQIRAELQN 7554
Query: 2489 KTEEIYDLKRLLLNEKNGL--HAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQR 2662
K ++ D +++ EK L E K K LQE +L E + +
Sbjct: 7555 KQRDMDDTTNIMMKEKAELARDLENLQNEKDELQKSRENIQKLMKELQEERLKTSEALNK 7614
Query: 2663 YKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLA-------------EKLSDALKKSAD-- 2797
+ EE++ K DSL + E D + L +K D ++S +
Sbjct: 7615 ERQQ--FTEEIKLKNDSLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDVRRQSDESD 7672
Query: 2798 ------HAQRES------HLLKHIADLEAGITD-----REIMTS-VCSDVLTALFVEMVR 2923
+RES +LK DLE + R + T + ++ + L E++
Sbjct: 7673 IARANLQRERESLDQLSVEILKQKQDLERERDELLEQWRLVETQKMDNENVKQLKTELLD 7732
Query: 2924 EKEFSLSLATKEQET---VNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEE 3094
EKE + + + ++ + + +++L K LE+ + + +E + +R L+ ++
Sbjct: 7733 EKESTEKIRKQLEQDKAYMEENKLNLHKELEELNLQKQGIQDERAQLERMKGELQMKADD 7792
Query: 3095 TENNPGRVFLQSEE-REKIEEQKRV---LDQALQECEELKNDIQNKHSDIDSLREEQEKL 3262
E + + ++ E+ E ++ LD+A E ++L +++ +++ + E +K
Sbjct: 7793 IERKMQEILYEKQKYAERKSENYKIQTYLDEANAEVQKLNKELERYDENLEKCKLELDKA 7852
Query: 3263 NKQLR-----CMXXXXXXXXXXXXXXXXXXXXISSNL-------DSMQLELRNYNEELKN 3406
+ I NL + + E+R ++EL
Sbjct: 7853 RAETERVKQGAKIPETQQIEQSLQKERDYIEDIRRNLFKKEEAIEKDKAEIRLRHQELDL 7912
Query: 3407 EIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATRE 3586
K + ++K+K E + +K +++ E L +K+ + +++++ L+ Q T
Sbjct: 7913 IQAKVVKQKEEMVKQKIESEREIQQEKKKLQRSEEELEDKMQKIKREMIELKLLQDETDG 7972
Query: 3587 QTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKE 3766
+ + + + + + +L+K + A E SK+ +++ M T+ + + + ++
Sbjct: 7973 KRKDVDNKMRQVARKRDELEK--MKADVESASKKLEVDRVMLNTERDELERIKTESQRAT 8030
Query: 3767 KDLQLRAFEIA 3799
+ +Q A E A
Sbjct: 8031 EHMQSHAEERA 8041
Score = 70.9 bits (172), Expect = 4e-09
Identities = 202/1162 (17%), Positives = 457/1162 (39%), Gaps = 73/1162 (6%)
Frame = +2
Query: 527 VSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVI------------- 667
+ EEF+ + +D L ++ E +N I +L + ++ E++
Sbjct: 1300 IQRAREEFELRVEERD-----LEEEKEQMNLTIINLIQQIEATREMVHKTKFQFENRMAG 1354
Query: 668 -----LSSHETISERDRLLKDFIHEKDLMQQRAQETEQ--KLASRDNEMMHMVLEKDNII 826
E +E RL+ + H +++++ E EQ ++ RD E + ++ + +
Sbjct: 1355 SQMGTADQEEMNAEMQRLILEIEHIREMLRGLKGEVEQNKEIMKRDREEIRLLKIE---V 1411
Query: 827 LSLHKQIELQSQNTQSLDCFRRDEIE-----DQNIKEEIEKQIVETIYVTQIQELGEEHD 991
++IE + + +DE+E Q +EE+E+++ E I +E+D
Sbjct: 1412 QRRRREIEYREEKIMR----EQDELELMSKMGQRQREELEERLEEVI---------KEND 1458
Query: 992 LLRLESAKYQDEIQSLKDECHAKE-MSKQAEISKLSHTLEESIMNSNLESLFTAE----- 1153
R+E + +D +LKD AKE + +Q E+ + + E T E
Sbjct: 1459 --RVEQMR-EDVNNALKDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAIK 1515
Query: 1154 IYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXX 1333
Y + EL I + R ++ I ++ + + ++
Sbjct: 1516 SYRASDLELSASIQKERQELEHYKEIILKEKHELNKIKEDVKAVKNDAEERMIKLHEEEK 1575
Query: 1334 XXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXX 1513
T + S++ +L+ E E+ N + + + N +L ER + +
Sbjct: 1576 EMKTKRVSLQNWERQLQTEKEK-------NQKGLDAIWNENQQLNERKQQLDIKELHLQS 1628
Query: 1514 XXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSV--IDKKEAEVSGHLDTISSLQTV 1687
V+ ++L E + ++ S+ +DK+ + + + +
Sbjct: 1629 EKSKLEYKKPLEIKQVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCT 1688
Query: 1688 LSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRA 1867
+ Q EIE S+ L E+ ++ + L + L D T
Sbjct: 1689 MERQMAEIELSRDELSLREATLQTATQTTA----DMELQLELQKQELEQTKDEMERTKLE 1744
Query: 1868 FVK---NIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHD-- 2032
K ++Q Q+A S+E+ E + ELE A VLN D+ + + E +
Sbjct: 1745 VQKGWVDLQTQIAESREK--EEMVRIELEK--ARDVLNRIRQDVETEKQTMEADLKFTLA 1800
Query: 2033 ---DEFDAERIALLNELKSL-HQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQ---E 2191
+ +A+R + +E ++L + EL + ++ +N+ + + +++ ++ E
Sbjct: 1801 KEFENLEAQRKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWE 1860
Query: 2192 GKDGEASDVQG----KSRALR-----RHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEE 2344
+ + D+Q +SR ++ R + D+ SE + E
Sbjct: 1861 ELEKKRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIEN 1920
Query: 2345 KKLLAILAFETADASDSPLRNWPKEQ--LLGHFKQSFAGLKREYELELQRKTEEIYDLKR 2518
+K + + L KE + + LK+ + E+ + +++ D+ +
Sbjct: 1921 EKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQD-EIAEQLKQVGDMMQ 1979
Query: 2519 LLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQ 2698
NEK+ L ++T + L+ KL+ E + ++L E+ +
Sbjct: 1980 FTQNEKDNLDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLL----EDCR 2035
Query: 2699 SKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDR-EIMT 2875
SL++++++ + K+ E+ + ++ E L+ + A T++ I T
Sbjct: 2036 I---SLMRDMQDLEQ-MKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDT 2091
Query: 2876 SVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEH 3055
L VE+ +E++ +++A E +K+ + K+ +K + +
Sbjct: 2092 LAEKQKLEDAAVELQKERDEIMNIA----EETKRKREDVDKIRVGIEKQEITFKDLKADL 2147
Query: 3056 KRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECE-------ELKNDIQ 3214
+++ AI+E ++ + + V + +I+++++ +D+ ++E E E++ ++
Sbjct: 2148 QKEAAIVENQRQAVQKDIQNV---KDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVD 2204
Query: 3215 NKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNE 3394
+ +++S R+E E+ +LR I D+++L+ N ++
Sbjct: 2205 KERQEVESKRDELEQETSKLR---EDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISK 2261
Query: 3395 EL------KNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILL 3556
E K + + + + K+ +EL +L + +EQ +A ++ +K
Sbjct: 2262 ERTIFELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQ----RKKAEY 2317
Query: 3557 LESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEE---LQSKERDLEVAMTETKFL 3727
+++++ E+ R + SL EE+ +++KQ E+ +S+ + LE+ K
Sbjct: 2318 VKTARGRETTALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKY 2377
Query: 3728 KEKLLVSDENLKEKDLQLRAFE 3793
KEKL D+ ++ Q + FE
Sbjct: 2378 KEKL---DKEYEDLQFQRQLFE 2396
Score = 63.5 bits (153), Expect = 7e-07
Identities = 89/436 (20%), Positives = 190/436 (43%), Gaps = 38/436 (8%)
Frame = +2
Query: 2588 VAEITGKFEKVLQENKLLPVEEVQRYKMLCVLK----EELQSKIDSLLKE--------IK 2731
V ++ +QE + + +E+V R K + ++ E+ +S I ++E +K
Sbjct: 14665 VTKLEDTLTSEVQEMRDMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEETLK 14724
Query: 2732 EKDSNSKVLAEKLSDA--LKKSADHAQRESHLL-----KHIADLEAGIT----DREIMTS 2878
EK N + L + L D L + D +E + ++IA LE I D+E +
Sbjct: 14725 EKSRNEETLLQLLHDKDDLSNTLDEKSKEIENITVTFKRNIAQLETTIAMMKKDKE---N 14781
Query: 2879 VCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHK 3058
+ +++L E RE + + E+E ++K ++ + LED +E K+
Sbjct: 14782 IENELLQLKQTEQEREIQRGTDDTSNERENYDEK-VTYKTELEDS--------KEKKKPD 14832
Query: 3059 RQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHS---D 3229
R + L+ ++ G Q+ E K+++ ++ D Q+ EEL ++++NK +
Sbjct: 14833 RDSS-LKLTDADSAKTDGEREAQTLET-KVQDVLQLTDYTTQDQEELHDEMENKMKIILE 14890
Query: 3230 IDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNE----- 3394
++ +++ +KL ++ R + S + S+ E+ + +
Sbjct: 14891 LNEAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEM 14950
Query: 3395 ---ELKNEIEKKST----DIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKIL 3553
E+K +I+ +S + D+ I++ +E E + K E++ + K + +
Sbjct: 14951 QQIEIKMQIQTRSVATQWETDVQIQQGQEATETTGHITKKSEEEISAKKTK----QPTVT 15006
Query: 3554 LLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKE 3733
LE + ++ + ++ RD LN E+ A +K ++L+ + D++ M E + E
Sbjct: 15007 KLEDTLTS---EVQEMRDSLNKEMEDVARMKTIMKMEKDQLEQAKSDIQTQMEEFERNME 15063
Query: 3734 KLLVSDENLKEKDLQL 3781
+ + +EK LQL
Sbjct: 15064 EAMEEKSRNEEKLLQL 15079
>ref|XP_005159738.1| PREDICTED: titin isoform X1 [Danio rerio]
Length = 15746
Score = 136 bits (343), Expect = 6e-29
Identities = 241/1198 (20%), Positives = 484/1198 (40%), Gaps = 108/1198 (9%)
Frame = +2
Query: 539 EEEFKEALAAKD---SENFLLNKKIEDLNHKIWSLE---ETLQYKEEVILSSHETISERD 700
E + KE L K+ S+ LL K +E+L K+ +E E+L+ E++ + E + +
Sbjct: 3377 EIQMKEVLTEKELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMK 3436
Query: 701 RLLKDFIHEKDLM----QQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNT 868
L+ E + + Q Q E+ A + ++ DNI +H + Q
Sbjct: 3437 TDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMK 3496
Query: 869 QSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDE 1048
Q D + + E QN+++E+EK+ + I + EL + L + D I+++K+E
Sbjct: 3497 QKQDELDQLKTEIQNLQQELEKE--KEIIMKDRSELDLKQSELDKQQTNMNDIIETMKNE 3554
Query: 1049 CHAKEMSKQA------EISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRND 1210
+ K+ EI K H ++ NS E L ++ + F E +++ Q++ +
Sbjct: 3555 RKQLDKDKEEMEEQKREIEKEKHDFDQG-RNSLDEDLKMMKLQKQVFEEEKNKLEQMKIE 3613
Query: 1211 MYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDE 1390
L E +++ K+K+E
Sbjct: 3614 -----------------LEREAGEIR-----------------------------KIKEE 3627
Query: 1391 LEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMA 1570
++ ER + + E + + ++ LAE +K + I
Sbjct: 3628 IQNERQSLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEK------ 3681
Query: 1571 FGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESH 1750
S EE+ + I+ + K+ + D + LQ + Q+ EIEK + ++S +
Sbjct: 3682 --SNFEEMRENISKQTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAA 3739
Query: 1751 IEKLVNDSLHEVDSAFCSLNSRFYSL---IHKVDNSGETLRAFVKNIQNQV----AVSQE 1909
I K+V D H++ SL+ SL +N E L+ ++ + + E
Sbjct: 3740 IIKIVEDLQHKI----ISLDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLE 3795
Query: 1910 QHIEHQCKEELEGHIA----------------DLVLNDFSNDILS--WSRRKEEAVVHDD 2035
+ Q EE+ I D+VLN+ + DI S + ++ ++ +
Sbjct: 3796 TQHDRQRVEEMTAQITKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKE 3855
Query: 2036 EFDAERIALLNELKSLHQDL---------ELLKAEEAVKSLSNNVGVSTKGIHYFSQLI- 2185
+ + E+ +EL + +DL E+ K E ++ ++ N+ + I + + +
Sbjct: 3856 KHNLEKTR--SELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQMK 3913
Query: 2186 --QEGKDGEASDVQGKSRALRRHS-------------TGQAFREPPKPEDLYTTY-SEGK 2317
Q+ D +++Q + L + + ++ D+ T +E K
Sbjct: 3914 QKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNERK 3973
Query: 2318 IVEPHPTEEKKLLAILAFETADASDSPLRNWPKE-QLLGHFKQSFAGLKREYE---LELQ 2485
+++ E ++ + E D D +++ ++ +++ KQ K + E ELQ
Sbjct: 3974 LLDKDKEEMEEQKQEMEKE-RDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQ 4032
Query: 2486 RKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXV--AEITGKFEKVLQENKLL---PVE 2650
R+ +EI +K NE+ L V AE T + +++L E ++ +
Sbjct: 4033 READEIRKIKEETQNERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMA 4092
Query: 2651 EVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKH 2830
++QR K + EE++ I ++I+ + SK+ ++L L+ Q E + K
Sbjct: 4093 DLQREKRIL---EEMRENISKQTEDIENEKEKSKLREDELK-KLQTEVQKQQSEIDMEKT 4148
Query: 2831 IADLEAGITDRE---IMTSV--CSDVLTALFVEMVREKEF---SLSLATKEQETVNQKQM 2986
+ E + RE +MT + S+ + E++ EKE +L K+ E + QK M
Sbjct: 4149 NIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLM 4208
Query: 2987 SLRKMLEDKDKLLCLVGEEN---KEHKRQIAI----LEKLKEETENNPGRVFLQSEEREK 3145
S+ + E G E K+ K + I +EK+K ET+++ RV E+ +
Sbjct: 4209 SIERDSESLKLDREAFGNEKEVLKQMKTDLQIQADEIEKIKLETQHDRQRV---EEKTAQ 4265
Query: 3146 IEEQKRVLDQALQE-------CEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXX 3304
I++ + ++ + E E+ DI+ K I S++ +++ L K+
Sbjct: 4266 IQKDRDEINNLIVETNRKDMVLNEMDRDIEEK---IKSIQSDKDMLEKE----------- 4311
Query: 3305 XXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYT 3484
NL+ + EL E L+ + E + DI+ + K + +
Sbjct: 4312 --------------RHNLEKTRSELARAKENLETQREIERKDIEKMKKNISREMHEIKHQ 4357
Query: 3485 QKAMEQKEAVL---------VEKLFEGEQKILLLESSQSATRE-QTEKYRDLLNSLTEEH 3634
++ M+QK+ L +++ E E++I++ SQ R+ + +K + +N + E
Sbjct: 4358 EEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETM 4417
Query: 3635 ADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSE 3808
+ +KQ EE + +++++E + ++ L DE+LK LQ + E S+
Sbjct: 4418 KNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSL---DEDLKMMKLQKQVIEEEKSK 4472
Score = 124 bits (310), Expect = 4e-25
Identities = 247/1298 (19%), Positives = 522/1298 (40%), Gaps = 115/1298 (8%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNT 451
IE E L+ K K A+ + +++ + L+ M +L ++ L ED +
Sbjct: 4726 IEEEKNKLEQMKIELEKEADEIRKIKEETQNERQRLEKMTEELKKEKESFTHLAEDTKTE 4785
Query: 452 KDLLDTV-------------------ESGLYVSNVVSDAV---------------LNGVV 529
K +LD + E +S D+ L +
Sbjct: 4786 KKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQLQAEI 4845
Query: 530 SAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLE---ETLQYKEEVILSSHETISERD 700
Q+ E K + +SE + K ++DL HK++SL+ E+L+ E + E + +
Sbjct: 4846 HKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREVLKQIK 4905
Query: 701 RLLKDFIHEKDLMQQRAQETEQKLAS--------RD--NEMMHMVLEKDNIILSLHKQIE 850
LK E + ++ Q Q++ RD N ++ KD ++ + +I+
Sbjct: 4906 TDLKRKAEEIEKIKLETQHDRQRVEEMTAQIQKERDKINNLIEETNRKDMVLNEIKTEIK 4965
Query: 851 LQSQNTQSLDCFRRDEIEDQN------------IKEEIEKQIVETIYVTQIQELGEE--- 985
+ + +S RD +E + KE +EKQ I + +IQ+ E+
Sbjct: 4966 EKIKAIES----DRDMLEKEKHDLEKTRSKLLRAKENLEKQ--RKIKLAEIQKEREDLEK 5019
Query: 986 ---------HDLLRLESA--KYQDEIQSLKDECH--AKEMSKQAEISKLSHTLEESIMNS 1126
HD+ E + QDE+ LK E +E+ K+ EI + + + S
Sbjct: 5020 MNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRS-QLDLRQS 5078
Query: 1127 NLESLFT-----AEIYENTFRELG---DQISQLRNDMYSKNSYIDSLASRIDFLSSECNK 1282
L+ T E +N ++L ++ + + +M + D +D + K
Sbjct: 5079 ELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDE-DLKMMK 5137
Query: 1283 LQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISK-LQKMNN 1459
LQ+Q +A ++ K+K+E++ ER +NLE++++ L++
Sbjct: 5138 LQKQVLEDEKSKLEQMKIELEREA---VEIRKIKEEIQNER----QNLEKMTEALKEERE 5190
Query: 1460 ELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKE 1639
+LAE +K N + S LEE+ + I+ ++ K+
Sbjct: 5191 DLAEETKKNNQVLDEMKVANESTLADILREK--------SNLEEMRENISKQTEDVENKK 5242
Query: 1640 AEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEV-----DSAFCS 1804
+ D + LQ + Q+ EIEK + ++S + I K V D H++ D+
Sbjct: 5243 ENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLK 5302
Query: 1805 LNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFS- 1981
L+ + +N E L+ ++ + ++ +E Q + +A + D
Sbjct: 5303 LDREAF------ENEKEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDE 5356
Query: 1982 -NDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTK 2158
N+++ + RK+ V+++ D E ++KS+ D ++L+ E+ +++ +
Sbjct: 5357 INNLIEETNRKD-MVLNEKNRDIEE-----KIKSIQSDKDMLEKEK------HDLEKTRS 5404
Query: 2159 GIHYFSQLIQEGKDGEASDVQGKSRALRRHSTG----------QAFREPPKPEDLYTTYS 2308
++ + +++ K+ +++Q + L + + Q + K ++L +
Sbjct: 5405 ELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKT 5464
Query: 2309 EGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQR 2488
E + ++ +EK+++ D S LR ++ + +K E + +L +
Sbjct: 5465 EIQNLQQELEKEKEIIM------KDRSQLDLRQSELDKQQTNMNDIMETMKNERK-QLDK 5517
Query: 2489 KTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYK 2668
EE+ + K+ + E++ + + + +K ++ K + EE + +
Sbjct: 5518 DKEEMEEQKQEMEKERDNMDQSR------------KSLDEDQKKMKLQKQMFEEEKNKLE 5565
Query: 2669 MLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDAL---KKSADHAQRESHLLKHIAD 2839
+ K EL+ + D + K IKE+ N + EK+++ L K+S H ++ K I D
Sbjct: 5566 QM---KIELEREADEISK-IKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILD 5621
Query: 2840 LEAGITDREIMTSVCSD--VLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDK 3013
E + + M + + +L + + + KE+ E+E ++ L+K+ +
Sbjct: 5622 -EMKVANESSMADLQREKSILEEMRENISKLKEY----IDNEKEKSKLREDELKKLQTEV 5676
Query: 3014 DKLLCLVGEE--NKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQE 3187
K + E N E +R I EK + +E ++K E+ + + + L E
Sbjct: 5677 QKQQSKIDMEKTNIESERAAMIREKQN-----------MMTELKKKSEDVEIQMKEILTE 5725
Query: 3188 CEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSM 3367
E L ND + D+++L+++ L + + + + D +
Sbjct: 5726 KELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEI 5785
Query: 3368 QLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQK 3547
+ +++ + + +E+ + I KE++++N + T + K+ VL EK + E+K
Sbjct: 5786 E-KIKLETQHDRQRVEEMAAQIQ---KERDKINNLIEETNR----KDMVLNEKNRDIEEK 5837
Query: 3548 ILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEV-------A 3706
I ++S + ++ + L + DL+KQ + E+Q + D+E
Sbjct: 5838 IKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENITRE 5897
Query: 3707 MTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQYQ 3820
M E K +E++ N K+ +L EI N +++ +
Sbjct: 5898 MHEIKHQEEQM-----NQKQDELDQLKTEIQNLQQELE 5930
Score = 122 bits (307), Expect = 9e-25
Identities = 261/1290 (20%), Positives = 533/1290 (41%), Gaps = 129/1290 (10%)
Frame = +2
Query: 296 DTRKSLETKIAETLERMEIH----EGDTANTLK---NMNFDLGQDNPGVPGLLEDIRNTK 454
D K L+T++ + ++++ E + A ++ NM +L + + V +++I K
Sbjct: 5667 DELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEIQMKEILTEK 5726
Query: 455 DLLDTVESGLY--VSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIW 628
+LL L V N+ + + + K A ++E + + DL +
Sbjct: 5727 ELLHNDRKLLTRDVENLQQKLI---DLERDSKRLKLDREAFENEKEAMKQMKTDLQIQAD 5783
Query: 629 SLE----ETLQYKEEVILSSHETISERDRL--LKDFIHEKDL-MQQRAQETEQKLASRDN 787
+E ET ++ V + + ERD++ L + + KD+ + ++ ++ E+K+ S +
Sbjct: 5784 EIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQS 5843
Query: 788 EMMHMVLEKDNI------ILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVET 949
+ + E+ N+ + + + +E Q +NT + R+++E N E I +++ E
Sbjct: 5844 DKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKMN--ENITREMHEI 5901
Query: 950 IYVT-QIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMS----KQAEISKLSHTLEES 1114
+ Q+ + +E D L+ E Q E++ K E K+ S +Q+E+ K +++
Sbjct: 5902 KHQEEQMNQKQDELDQLKTEIQNLQQELEKEK-EIIMKDRSQFDLRQSELDK-----QQT 5955
Query: 1115 IMNSNLESLFTAEIYENTFRELG---DQISQLRNDMYSKNSYIDSLASRIDFLSSECNKL 1285
MN +E++ +N ++L +++ + + +M + D +D + KL
Sbjct: 5956 NMNDIMETM------KNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLD-KDLKMMKL 6008
Query: 1286 QEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNEL 1465
Q+Q +A + K+K+E + ER + + E + K ++ L
Sbjct: 6009 QKQVFEEEKNKLEQMKIELEREAD---EIRKIKEETQNERQSLEKMTEELKKEKESFTHL 6065
Query: 1466 AERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAE 1645
AE +K + I S LEE+ + I+ ++ K+
Sbjct: 6066 AEDTKKEQEILDKVKVANESLMADLQKEK--------SNLEEMRENISKQTEDVENKKEN 6117
Query: 1646 VSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEV-----DSAFCSLN 1810
+ D + LQ + Q+ EIEK + ++S + I K V D H++ DS L+
Sbjct: 6118 LRLREDELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLD 6177
Query: 1811 SRFYSLIHKVDNSGETLRAFVKNIQNQV----AVSQEQHIEHQCKEELEGHIADLVLNDF 1978
+ +N E L+ ++ + + E + Q EE+ I D
Sbjct: 6178 REAF------ENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQK--DRDK 6229
Query: 1979 SNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTK 2158
N+++ + RK + V+++ D E+ ++KS+ D ++L+ E+ +++ +
Sbjct: 6230 INNLIEETNRK-DMVLNEKNRDIEK-----KIKSIQSDKDMLEKEK------HDLEKTRS 6277
Query: 2159 GIHYFSQLIQEGKDGEASDVQGKSRALRRHSTG----------QAFREPPKPEDLYTTYS 2308
++ + +++ K+ + +Q + L + + Q + K ++L +
Sbjct: 6278 ELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKT 6337
Query: 2309 EGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQR 2488
E + ++ +EK+++ + A D S L K+Q + +K E + +L +
Sbjct: 6338 EIQNLQQELEKEKEII-MKARSQLDRRQSEL---DKQQT--NMNDIMETMKNERK-QLDK 6390
Query: 2489 KTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYK 2668
EE+ + K+ + E++ + K+++ K + EE + +
Sbjct: 6391 DKEEMEEQKQEMEKERDNMDQSRKSLDEDL------------KMMKLQKQVIEEEKNKLE 6438
Query: 2669 MLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKS-------ADHAQRESHLL- 2824
+K EL+ + D +++IKE+ N + + EK+++ LKK A+ +RE + L
Sbjct: 6439 Q---MKIELEREADD-IRKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTKREKNSLD 6494
Query: 2825 -------KHIADLEAGITDREIMTSVCSDVLTALFVE----MVREKEF---------SLS 2944
+ADL+ ++ E M S + E +RE E S
Sbjct: 6495 EMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQS 6554
Query: 2945 LATKEQETVNQKQMSLRKMLED-KDKLLCL------------VGEENKEHKRQIAI---- 3073
E+ + +++ ++ K +ED + K++ L E KE +Q+
Sbjct: 6555 ETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELER 6614
Query: 3074 ----LEKLKEETENNPGRV------FLQ--SEEREKIEEQKRVLDQALQECEELKNDIQN 3217
+EK+K ET++ RV F++ + ER+++++ K ++++ QE E+ ++D+
Sbjct: 6615 EADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQ 6674
Query: 3218 KHSDIDS-----------LREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDS 3364
+D L EE+ KL + M NL+
Sbjct: 6675 SRKSLDEDLKMMKAQKQVLEEEKNKLEQ----MKIGLEREADEISKIKEETQNERQNLEK 6730
Query: 3365 MQLELRNYNEELKNEIEKKSTDIDL-----------LIKEKEELNERLAYTQKAMEQKEA 3511
M L+ E L EI++K+ +D L KEK L E K +E E
Sbjct: 6731 MANALKEEREYLAEEIKRKNQVLDKIKVANESTLADLQKEKRILEEMRENISKQIEDIEN 6790
Query: 3512 VLVE-KLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKE 3688
+ KL E E K L E + + EK ++ E A + ++ + EL+ K
Sbjct: 6791 EKEKSKLREDELKKLQTEVQKQQSEIDMEK-----TNIESERAAMIREKQNMMTELKKKS 6845
Query: 3689 RDLEVAMTETKFLKEKLLVSDENLKEKDLQ 3778
D+E+ M E KE LL +D NL +KD++
Sbjct: 6846 EDVEMQMKEILTEKE-LLHNDRNLLKKDVE 6874
Score = 115 bits (287), Expect = 2e-22
Identities = 245/1253 (19%), Positives = 499/1253 (39%), Gaps = 71/1253 (5%)
Frame = +2
Query: 275 EVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTK 454
E ED +T+K+ + L+ M++ T + +L + + ED+ N K
Sbjct: 5188 EREDLAEETKKN-----NQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKK 5242
Query: 455 DLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSL 634
+ L E L L + Q+ E ++ +SE + K +EDL HKI L
Sbjct: 5243 ENLRLREDEL--------RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICL 5294
Query: 635 E---ETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMV 805
+ E+L+ E + E + + L+ E + ++ Q Q++ E M
Sbjct: 5295 DRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIKLETQHDRQRV-----EEMAAQ 5349
Query: 806 LEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEE 985
++KD ++ IE ++ L+ RD IE++ + +K ++E E+
Sbjct: 5350 IQKDRD--EINNLIEETNRKDMVLNEKNRD-IEEKIKSIQSDKDMLEK----------EK 5396
Query: 986 HDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYEN 1165
HDL K + E+ +K++ ++ + AEI K LE+ MN N+ T E++E
Sbjct: 5397 HDL-----EKTRSELYKVKEDLEKQKENTLAEIQKEREDLEK--MNENI----TREMHEI 5445
Query: 1166 TFRE------------LGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXX 1309
+E L +I L+ ++ + I S++D SE +K Q
Sbjct: 5446 KHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIM 5505
Query: 1310 XXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISEN---LERISKLQKMNNELAERSK 1480
K ME Q K E+E+ER + ++ L+ K K+ ++ E K
Sbjct: 5506 ETMKNERKQLDKDKEEMEEQ----KQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEK 5561
Query: 1481 SQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHL 1660
N + N +LE++T+++ +E E HL
Sbjct: 5562 --NKLEQMKIELEREADEISKIKEETQNKR--QRLEKMTEELI--------REKESLAHL 5609
Query: 1661 -DTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHK 1837
+ + + +L K E S LQ +S +E++ L
Sbjct: 5610 AEDTKTEKKILDEMKVANESSMADLQREKSILEEM---------------RENISKLKEY 5654
Query: 1838 VDNSGETLRAFVKNIQN-QVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKE 2014
+DN E + ++ Q V ++Q K +E A ++ + N + ++ E
Sbjct: 5655 IDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMI-REKQNMMTELKKKSE 5713
Query: 2015 EAVVHDDEFDAERIALLNELKSLHQDLELLKAEEA-VKSLSNNVGVSTKGIHYFSQLIQE 2191
+ + E E+ L N+ K L +D+E L+ + ++ S + + + + +++
Sbjct: 5714 DVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQ 5773
Query: 2192 GKDG---EASDVQGKSRALRRHS-------TGQAFREPPKPEDLYTTYSEGKIV--EPHP 2335
K +A +++ K + +H Q +E K +L + +V E +
Sbjct: 5774 MKTDLQIQADEIE-KIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNR 5832
Query: 2336 TEEKKLLAILAFETADASDSPLRNWPKEQL-LGHFKQSFAGLKREYELELQRKTEEIYDL 2512
E+K+ +I + + D + N K + L K+ K E+Q++ E++ +
Sbjct: 5833 DIEEKIKSIQSDK--DMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKM 5890
Query: 2513 KRLLLNEKNGL---HAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQ---RYKML 2674
+ E + + EI +++ +E +++ + Q R L
Sbjct: 5891 NENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQFDLRQSEL 5950
Query: 2675 CVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGI 2854
+ + ++++ E K+ D + + + E+ + K+ D Q L K DL+
Sbjct: 5951 DKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDK---DLKMMK 6007
Query: 2855 TDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLV 3034
+++ + L + +E+ RE + + ++ET N++Q SL KM E+ K
Sbjct: 6008 LQKQVFEEE-KNKLEQMKIELEREAD---EIRKIKEETQNERQ-SLEKMTEELKKEKESF 6062
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQ 3214
++ K++ IL+K+K E+ + +E+ +EE + + + ++ E K +++
Sbjct: 6063 THLAEDTKKEQEILDKVKVANESLMADL---QKEKSNLEEMRENISKQTEDVENKKENLR 6119
Query: 3215 NKHSDIDSLREEQEKLNKQLRC--MXXXXXXXXXXXXXXXXXXXXISSNLDSMQLEL--- 3379
+ ++ L+ E K +++ + IS + DS L+L
Sbjct: 6120 LREDELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDRE 6179
Query: 3380 -----RNYNEELKNEIEKKSTDIDLLIKE----KEELNERLAYTQKAME----------Q 3502
R +++K E+E+++ +I+ + E ++ + E A QK + +
Sbjct: 6180 AFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNR 6239
Query: 3503 KEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQS 3682
K+ VL EK + E+KI ++S + ++ + L + DL+KQ + ++Q
Sbjct: 6240 KDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQK 6299
Query: 3683 KERDLEV-------AMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQYQ 3820
+ DLE M E K +E++ N K+ +L EI N +++ +
Sbjct: 6300 EREDLEKMNENITREMHEIKHQEEQM-----NQKQDELDQLKTEIQNLQQELE 6347
Score = 114 bits (285), Expect = 3e-22
Identities = 238/1256 (18%), Positives = 500/1256 (39%), Gaps = 82/1256 (6%)
Frame = +2
Query: 287 GGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLD 466
GGL T + LE+M+ + ++M L ++ + L +DI K+ D
Sbjct: 8864 GGLKTEIENTKRDKSNLEKMKAELEEKQQEEESMREILQKEKEELEQLKKDINREKE--D 8921
Query: 467 TVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETL 646
S V + + + + G Q+ +KE L E + +E LN + L +TL
Sbjct: 8922 IEISRELVESEIYEGEVKGFTDVQK--YKEELQIVTEELLTKKRNLEQLNSDVQHLMQTL 8979
Query: 647 QYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQK-LASRDNEMMHMVLEKDNI 823
EEV + + +E + + + + +++++ ++ E+ + EMM + LE N+
Sbjct: 8980 ---EEVDIQYIKKKAELEHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINM 9036
Query: 824 -ILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLR 1000
IL + +E + +N RR++ E + + E+++Q E + Q L E D +
Sbjct: 9037 EILQKREDMEKEKEN------LRREKQETELFRGELQRQRDEV--ESSRQALIMEKDQFK 9088
Query: 1001 LESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFREL 1180
L+ ++E+ + ++ H + + + ++ L ES+ N ++
Sbjct: 9089 LKIDHQRNEMSAAFEKEHKRLENMENDLENQRAKLAESL---------------NDAAKM 9133
Query: 1181 GDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASM 1360
++ Q++N++ + ++ + + +E K++++ L+
Sbjct: 9134 EQKLQQMKNELNKEKEQVEEMKQMV---KTERVKIEQEKEEMRKQTQEIEDGHEKLQKKT 9190
Query: 1361 EMQCSKLKD-ELEEERGK-ISENLE-RISKLQKMNNELAERSKSQNSIXXXXXXXXXXXX 1531
E+ L+D E +R K +S L+ + ++K N E+ + +S + +
Sbjct: 9191 EIADKLLQDANSESDRLKDLSMKLQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLK 9250
Query: 1532 XXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEI 1711
+ + E + + ++ ++ ++E + K +I
Sbjct: 9251 NDRDAYEKDMTHLELKREELVRETEDLERKILQQREQDEMA---------------KRDI 9295
Query: 1712 EKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQ 1891
E + L+ + I K N+ E+++ +S K+ L++ ++N+
Sbjct: 9296 ENQTEALEVMKVDILKKRNEFAKEMENV--------HSERQKLLLLQGALQSQESELENR 9347
Query: 1892 VAVSQEQHIEH------QCKEELEGHIADLVL---NDFSNDILSWSRRKEEAVVHDDEFD 2044
V + +++H++ +C+++L +++ V N++ I R KE+ + ++ +
Sbjct: 9348 VFMEEQKHLKQAKAETEECRKQL-AEMSETVTTEQNEYRKLIEELQREKEQLEISKNQIE 9406
Query: 2045 AERIALLNELKSLHQDLELLKAEEA----VKSLSNNVGVSTKGIHYFSQLIQEGKDGEAS 2212
E+ L N +L + LE L+ E+A K+ + +K I + +E +
Sbjct: 9407 QEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWV 9466
Query: 2213 DVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAIL--AFETADA 2386
+++G+ + + E + +E H E KK+ + L + E ++
Sbjct: 9467 EIEGEKKRMEE---------------------ETRRLEMHREEIKKVDSELQKSRENIES 9505
Query: 2387 SDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDL---KRLLLNEKNGLHAXX 2557
+ + N +E L K K E E E QR + DL K + +++
Sbjct: 9506 REEKINNKMEELL--QMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDII 9563
Query: 2558 XXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKM-LCVLKEELQSKIDSLLKEIKE 2734
+ K K L E L V++++ + K+E++ L KE +E
Sbjct: 9564 DIKIQEKEREIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQE 9623
Query: 2735 KDSNSKVLAEKLSD----------------ALKKSADHAQRESHLLKHIADLE-AGITDR 2863
K L +++ D ALK + ++E+ ++K LE + I +
Sbjct: 9624 LKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEM 9683
Query: 2864 EIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQM---SLRKMLEDKDKLLCLV 3034
++ + E +EKE SL + ET QKQM S KM+E+K+++ L
Sbjct: 9684 QLKIFKQQRLNDQTREENKKEKE---SLEQQRFETEQQKQMLEISTTKMMEEKNEMADLS 9740
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVF-LQSE---EREKIEEQKRVLDQALQECEELK 3202
E K LEK+ +T V +Q+E + + IE+Q +++ EE +
Sbjct: 9741 RELQKAKDE----LEKIAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEKE 9796
Query: 3203 NDIQNKHSDI--------------DSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXX 3340
IQ K +I +++ EE K L M
Sbjct: 9797 LSIQRKEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQKNNKDFELLE 9856
Query: 3341 XISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEA--- 3511
I S L++ + +L+ + E+ K+ +E + +++ KEKE L + Q EQ E
Sbjct: 9857 KIRSELENEKYDLQIWTEQQKHLVEVQLQELE---KEKERLEKMEIELQSKREQTEKEKA 9913
Query: 3512 --------------VLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLK- 3646
V+ +K + + LE+ ++ +E+ EK + L EE ++
Sbjct: 9914 DLNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQI 9973
Query: 3647 --KQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSE 3808
+ EE++ ++ LE++ + K +KE+ + E + K + +I N+E
Sbjct: 9974 EAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEE-QIQNNE 10028
Score = 114 bits (284), Expect = 4e-22
Identities = 214/1216 (17%), Positives = 493/1216 (40%), Gaps = 33/1216 (2%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNT 451
+E E L+ +S K+ E LE+ + +T ++ DL + N + + +I++
Sbjct: 3852 LEKEKHNLEKTRSELYKVKEDLEKQK---ENTLAEIQKEREDLEKMNENITIEMHEIKHQ 3908
Query: 452 KDLLDTVESGLYVSNVVSDAVLNGVVSAQEE--EFKEALAAKDSENFLLNKKIEDLNHKI 625
++ + + L D + + + Q+E + KE + SE L +++ +
Sbjct: 3909 EEQMKQKQDEL-------DQLKTEIQNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNM 3961
Query: 626 WSLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMV 805
+ ET++ + +++ E + E +K M++ +Q + S D ++ M
Sbjct: 3962 NDIIETMKNERKLLDKDKEEMEE----------QKQEMEKERDNMDQSIKSLDEDLKMMK 4011
Query: 806 LEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEE 985
L+K I +K +++ + + D R+ + E QN ++ +EK I E
Sbjct: 4012 LQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQNERQSLEKMTKALIK--------ER 4063
Query: 986 HDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESL-FTAEIYE 1162
DL+ L A+Y + + DE S A++ + LEE N + ++ E +
Sbjct: 4064 EDLVHL--AEYTKREKEMLDEMQVANKSSMADLQREKRILEEMRENISKQTEDIENEKEK 4121
Query: 1163 NTFRELGDQISQLRNDMYSKNSYIDSLASRID----FLSSECNKLQEQXXXXXXXXXXXX 1330
+ RE D++ +L+ ++ + S ID + I+ + E + +
Sbjct: 4122 SKLRE--DELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQNMMTELKKKSEDVEIQM 4179
Query: 1331 XXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXX 1510
T K +E + LK ++E+ + K+ ++ER S+ K++ E
Sbjct: 4180 KEILTEKELLENDSNLLKKDMEDLKQKLM-SIERDSESLKLDRE---------------- 4222
Query: 1511 XXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVL 1690
AFG++ E V+ + + ++ D I ++
Sbjct: 4223 -------------------AFGNEKE-----------VLKQMKTDLQIQADEIEKIKLET 4252
Query: 1691 SNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAF 1870
+ + +E+ +Q I L+ ++ + D ++ I + + + L
Sbjct: 4253 QHDRQRVEEKTAQIQKDRDEINNLIVET-NRKDMVLNEMDRDIEEKIKSIQSDKDMLEKE 4311
Query: 1871 VKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAE 2050
N++ + + + E+E + + + S ++ ++E+ DE D
Sbjct: 4312 RHNLEKTRSELARAKENLETQREIERKDIEKMKKNISREMHEIKHQEEQMKQKQDELDQ- 4370
Query: 2051 RIALLNELKSLHQDLE-----LLKAEEAVKSLSNNVGVSTKGIHYFSQLI-----QEGKD 2200
L E+++L Q+LE ++KA + + + ++ + + Q KD
Sbjct: 4371 ---LKTEIQNLQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKD 4427
Query: 2201 GEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETA 2380
E ++ Q + +H Q+ + EDL + +++E ++ K++ L E
Sbjct: 4428 KEETEEQKQEMEKEKHDFDQSRKS--LDEDLKMMKLQKQVIEEEKSKLKQMKIELEREAD 4485
Query: 2381 DASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRL-------LLNEKN 2539
+ + Q+ ++ + + + +RK + + ++K +L E++
Sbjct: 4486 EIRKVKEETQNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRERS 4545
Query: 2540 GLHAXXXXXXXXXXXXVAEITGKFEKV-LQENKL--LPVEEVQRYKMLCVLKEELQSKID 2710
L ++ K EK+ L+E KL L E ++ K ++ +
Sbjct: 4546 NLQEMRENISKQ----TEDVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNIERERA 4601
Query: 2711 SLLKEIKEKDSNSKVLA-EKLSDALKKSADHAQRESHLLKHI-ADLEAGITDREIMTSVC 2884
+++K+++ D SK+++ ++ +++LK + + E LK + +LE RE
Sbjct: 4602 AIIKDVE--DLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELE-----RE------ 4648
Query: 2885 SDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQ 3064
+D + + +E E++ + ET+N ++ L K E+ E+ +E +++
Sbjct: 4649 ADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQ-------EQKQEMEKE 4701
Query: 3065 IAILEKLKEETENNPGRVFLQS----EEREKIEEQKRVLDQALQECEELKNDIQNKHSDI 3232
+++ ++ + N + LQ EE+ K+E+ K L++ E ++K + QN+ +
Sbjct: 4702 RHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEADEIRKIKEETQNERQRL 4761
Query: 3233 DSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEI 3412
+ + EE +K + + + ++L + L EE++ I
Sbjct: 4762 EKMTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNL----EEMRENI 4817
Query: 3413 EKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQT 3592
K++ D + KEKE++ R + +EQ +A + ++ +GE K +E S + +
Sbjct: 4818 SKQTEDSE---KEKEKIRLR----EDELEQLQAEIHKQ--QGEIK---MEKSNNESERA- 4864
Query: 3593 EKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKD 3772
++ ++ DL+ + S +L+S + D E E + LK+ + +D K ++
Sbjct: 4865 --------AIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREVLKQ--IKTDLKRKAEE 4914
Query: 3773 LQLRAFEIANSEKQYQ 3820
++ E + ++ +
Sbjct: 4915 IEKIKLETQHDRQRVE 4930
Score = 114 bits (284), Expect = 4e-22
Identities = 231/1252 (18%), Positives = 504/1252 (40%), Gaps = 81/1252 (6%)
Frame = +2
Query: 302 RKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESG 481
R L+ + +E L++ + + D T+KN L +D + +++ +D +D
Sbjct: 5484 RSQLDLRQSE-LDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKS 5542
Query: 482 LYVSNVVSDAVLNGVVSAQE----EEFKEALAAKDSENFLLNKKIEDLNHKIWSL-EETL 646
L L + +E E+ K L + E + ++ ++ ++ + EE +
Sbjct: 5543 LDEDQ--KKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELI 5600
Query: 647 QYKEEVILSSHETISERDRL----------LKDFIHEKDLMQQRAQETEQKLASRDNEMM 796
+ KE + + +T +E+ L + D EK ++++ + + DNE
Sbjct: 5601 REKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENISKLKEYIDNEKE 5660
Query: 797 HMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIED---------QNIKEEIEKQIVET 949
L +D + K+++ + Q QS + IE QN+ E++K+ +
Sbjct: 5661 KSKLREDEL-----KKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKKSEDV 5715
Query: 950 IYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEM-SKQAEISKLSHTLEESIMNS 1126
Q++E+ E +LL + ++++L+ + E SK+ ++ + + E+ M
Sbjct: 5716 --EIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQ 5773
Query: 1127 NLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXX 1306
L + D+I +++ + ++ +A++I + N L E+
Sbjct: 5774 MKTDL----------QIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRK 5823
Query: 1307 XXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQK-----MNNELAE 1471
S++ KD LE+ER + + + K+++ N LAE
Sbjct: 5824 DMVLNEKNRDIEEKIKSIQSD----KDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAE 5879
Query: 1472 RSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVS 1651
K + + E++ + I I +E +++
Sbjct: 5880 IQKEREDV------------------------------EKMNENITREMHEIKHQEEQMN 5909
Query: 1652 GHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLI 1831
D + L+T + N + E+EK ++++ S + + E+D ++N ++
Sbjct: 5910 QKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQFDLRQS----ELDKQQTNMND----IM 5961
Query: 1832 HKVDNSGETLRAFVKNIQNQVA-VSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRR 2008
+ N + L + ++ Q + +E+H Q ++ L+ DL + + +
Sbjct: 5962 ETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLD---KDLKMMKLQKQVFEEEKN 6018
Query: 2009 KEEAVVHDDEFDAERIALL-----NELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYF 2173
K E + + E +A+ I + NE +SL + E LK E K ++ TK
Sbjct: 6019 KLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKE---KESFTHLAEDTKKEQEI 6075
Query: 2174 SQLIQEGKDGEASDVQGKSRAL---RRHSTGQAFREPPKPEDLYTT-----------YSE 2311
++ + +D+Q + L R + + Q K E+L Y +
Sbjct: 6076 LDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQ 6135
Query: 2312 GKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLK---REYELEL 2482
+ +E + A + D + + L +++F + ++ + EL
Sbjct: 6136 QREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTEL 6195
Query: 2483 QRKTEEIYDLKRLLLNEKNGLH--AXXXXXXXXXXXXVAEITGKFEKVLQENKL---LPV 2647
+R+ +EI +K +++ + + E T + + VL E +
Sbjct: 6196 EREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKI 6255
Query: 2648 EEVQRYK-MLCVLKEELQSKIDSLLK---EIKEKDSNSKVLAEKLSDALKKSADHAQRES 2815
+ +Q K ML K +L+ L K +++++ N+ +K + L+K ++ RE
Sbjct: 6256 KSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREM 6315
Query: 2816 HLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSL---SLATKEQETVNQKQM 2986
H +KH E + ++ + L E+ +EKE + S + Q ++++Q
Sbjct: 6316 HEIKH---QEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQT 6372
Query: 2987 SLRKMLE---------DKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQS--- 3130
++ ++E DKDK + E+ +E +++ +++ ++ + + + LQ
Sbjct: 6373 NMNDIMETMKNERKQLDKDKEE--MEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVI 6430
Query: 3131 -EEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXX 3307
EE+ K+E+ K L++ + ++K + QNK ++ + EE +K K + +
Sbjct: 6431 EEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTKREK 6490
Query: 3308 XXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQ 3487
S++ +Q E N EE+K I K++ DI+ KEK+++ R +
Sbjct: 6491 NSLDEMKVAN---ESSMADLQKEKSNL-EEMKENISKQTEDIE---KEKDKIRLR----E 6539
Query: 3488 KAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLK---KQFL 3658
+EQ +A + ++ E E + +E ++A + E + + SL + LK + F
Sbjct: 6540 DELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFE 6599
Query: 3659 SATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQ 3814
+ EEL+ + +LE E + K KL E + +++ E N+E++
Sbjct: 6600 NEKEELKQMKTELEREADEIE--KIKLETQHERQRVEEMTADFMETMNNERK 6649
Score = 111 bits (277), Expect = 3e-21
Identities = 233/1162 (20%), Positives = 476/1162 (40%), Gaps = 76/1162 (6%)
Frame = +2
Query: 524 VVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDR 703
+V+ +EE K+ ++S N + KK +L H+ L + Q E++I S + + +R
Sbjct: 13348 LVNMEEEIKKQRRVLEESMNEMTKKK-SELQHERSELYKQKQQLEDMIASESKRDVDTER 13406
Query: 704 LLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDC 883
+D E+ L ++R + + K +L++ + + ++I + ++ + +
Sbjct: 13407 SRQDKEDEQILKREREEIADMK---------DQLLKEKEDVETTKERINREKEHIEKMQS 13457
Query: 884 FRRDEIEDQNIKEE------IEKQIVETIYVTQIQELGEEHD---LLRLESAKYQDEIQS 1036
D+ E+ +++ + E Q+ +Q+L +E + L ++ K +++
Sbjct: 13458 QLNDQKEEMDLENQKLLYMKTEIQVKTNALEKMMQDLQKERENVNALVIQHQKEREQRDI 13517
Query: 1037 LKDECHAKEMSKQAEISKLSHTLE----------ESIMNSNLESLFTAEIYENTFRELGD 1186
L +E KE +AEI + +E I N E +E EN ++
Sbjct: 13518 LIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTRSEELENLIKKQQK 13577
Query: 1187 QISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEM 1366
+ N+M + ++ + + ++ S+E E+ LK +E
Sbjct: 13578 EFETKENEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILER 13637
Query: 1367 QCSKLKDELEEERGKISENLERISKLQK-MNNELAERSKSQNSIXXXXXXXXXXXXXXXX 1543
+ K EL +E+ ++ + + ++K M +E+ +N +
Sbjct: 13638 E----KSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELE--------------- 13678
Query: 1544 XXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQ 1723
+ + + ++++ IDK + E+ ++I + L K E E +
Sbjct: 13679 -----------DEKKSMLSRLSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKR 13727
Query: 1724 KVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVS 1903
L ++ IEK+ D L + SL L K + E +R K +Q +S
Sbjct: 13728 TQL---DNTIEKMNMDKL-SIQREKDSLEEIKADLQRKAEKLDEEMR---KAVQITSQIS 13780
Query: 1904 QEQHI---EHQCKEELEGHIADL-----------VLNDFSNDILSWSRRKEEAVVHDDEF 2041
Q+ I + + +EEL AD+ L +IL S+ + + + D E
Sbjct: 13781 QDAKILDDDREKEEELRSMRADIERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEK 13840
Query: 2042 DAERIAL-LNELKSLHQDLE-----LLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDG 2203
+R L L EL+ LE + K ++AV SL N V + + + E +
Sbjct: 13841 QRKRNDLTLQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRK- 13899
Query: 2204 EASDVQGKSRALRRHSTGQAFREPPKPEDLYTT-----YSEGKIVEPHPTEEKKLLA--I 2362
E D++ +R++ST + +E D++ ++ + ++ EE++ L I
Sbjct: 13900 EMDDLR-MQLEMRQNSTNKQQQE----VDVFIVENMKMRNDLESMKTLLDEERRQLQDNI 13954
Query: 2363 LAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNG 2542
FE P + +Q ++ +K E E ++++ EEI L + ++ K
Sbjct: 13955 KTFEDQKNVLHPSKTDAVQQ-TDELEKFTTDIKTEKE-HVEKEREEIDVLNKEIIKSKEE 14012
Query: 2543 LHAXXXXXXXXXXXXVAEITGKFEKV-----LQENKLLPVEE----VQRYKMLCVLKEEL 2695
L + EI GK ++ L+ + L ++ VQ K + + E
Sbjct: 14013 LQSLNLEIEMFK----QEIAGKRAQIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEK 14068
Query: 2696 QSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLL-KHIADLEAGITDREIM 2872
+++++ + K+K+ E+L + ++ + +L K ++E +IM
Sbjct: 14069 KTEVELQMNLQKQKNE-----LEELRNTIEAEKHQVENRKIMLDKQQKEVE------DIM 14117
Query: 2873 TSVCS--DVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLE----DKDKLLCLV 3034
T + S DVL +EK L+ E V ++Q L ++LE D + ++
Sbjct: 14118 TVIKSERDVLE-------KEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKII 14170
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLD----QALQECEELK 3202
E + +R+ A L++LKEE E R LQ +++ I+++K L+ + +E LK
Sbjct: 14171 ESEKQSIERERAELKRLKEEVEVQHERTLLQ-QDKNMIQKEKEHLEGEKARTTEEIHNLK 14229
Query: 3203 NDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLE-- 3376
+I+ K S++D L +E E ++ + + +++E
Sbjct: 14230 EEIKRKSSELDMLNKEIEAKRQE----------------------EELHGLPEEIEIEDH 14267
Query: 3377 LRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQ-------KAMEQKEAVLVEKLFE 3535
L+ ++ L+ EI KK D K + + R A TQ K E+++ L E +
Sbjct: 14268 LKKEDDVLREEIIKKQ-QTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRALEETVAT 14326
Query: 3536 GEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTE 3715
++ ++++ + T E ++ RD LN+ +E A +K ++L+ + D++ M E
Sbjct: 14327 TAKQPIVIKLEDTLTSE-VQEMRDHLNNEIKELARMKTIMKMEKDQLKQAKSDIQTQMEE 14385
Query: 3716 TKFLKEKLLVSDENLKEKDLQL 3781
+ E+ + +EK LQL
Sbjct: 14386 FERNMEEAMEEKSRNEEKLLQL 14407
Score = 108 bits (270), Expect = 2e-20
Identities = 257/1319 (19%), Positives = 522/1319 (39%), Gaps = 140/1319 (10%)
Frame = +2
Query: 230 VMDGQGCDISVTSFIEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNF----- 394
+ D Q I S ++ E+ + + K ETL+ ME H +K+++
Sbjct: 10859 IADEQDLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRL 10918
Query: 395 --DLGQDNPGVPGLLEDIRNTKDLLDTVESGL-----YVSNVVSDAVLNGVVSAQ-EEEF 550
DL + + V +D+ N +DLL+ + + + + + VS Q E++
Sbjct: 10919 KEDLEKMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQQRIDE--FDAQVSKQKEQDL 10976
Query: 551 KEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEK 730
+ K+ L K + K + E ++ ++E E E R++ + K
Sbjct: 10977 PKEKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVE-TERK 11035
Query: 731 DLMQQRAQ--------ETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCF 886
+L Q +++ + EQK + N+ M M+ ++ + + +I Q Q +
Sbjct: 11036 ELYQIKSELERVRSEIDHEQK---KLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSE 11092
Query: 887 RRDEIEDQNI-KEEIEK--QIVETIYVT-----------------QIQELGEEHDLLRLE 1006
++I+ N+ K +IEK +IVE + V + Q++ +E +LL
Sbjct: 11093 LDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQN 11152
Query: 1007 SAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGD 1186
AK Q+E + +K EI K TL E ++ E I E T R D
Sbjct: 11153 KAKLQNENERIK--------KVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKED 11204
Query: 1187 QISQLRNDMYSKNSYI----DSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKA 1354
+ ++ D+ + ++ D L + ++ E +LQ++ A
Sbjct: 11205 -LEKMSTDINEQKLHLKNQRDLLEQEREEINHEMTQLQQRIDE--------------FDA 11249
Query: 1355 SMEMQCSKL-KDELEEERGKISENLERI------SKLQKMNNELAERSKSQNSIXXXXXX 1513
+ Q L K E+EEER + E RI ++LQ++ E E + + +
Sbjct: 11250 QVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRV------ 11303
Query: 1514 XXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLS 1693
+V M +L ++ ++ S ID ++ +++ I + L
Sbjct: 11304 --------------IVEME-REELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLE 11348
Query: 1694 NQKFEIEKSQKVLQSFESHIEKLVNDS---LHEVDSAFCSLNSRFYSLIHKVDNSGETLR 1864
K EI ++ ++ S ++ + + H+++++ L+ KV+ + +R
Sbjct: 11349 KMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENS----KEIVQKLMVKVEEQRKDIR 11404
Query: 1865 AFVKNIQ-NQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEF 2041
+ + + ++ EQ + Q K +L+ N+ ++ ++++E + E
Sbjct: 11405 LQKEELDIERQKIADEQGLVVQNKAKLQNE------NERIKEMDEEIKKEKETL---KEM 11455
Query: 2042 DAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQ 2221
+A E++S+ ++ + K E+ ++ +S +V + + L+++ E ++
Sbjct: 11456 EAHLRKEKEEMRSVIEETQRRKKED-LEKMSTDVNKQNQDLMNQRDLLKQ----EREEIN 11510
Query: 2222 GK-SRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSP 2398
K ++ +R A K EDL + K+ E + E+ + I+ +T +
Sbjct: 11511 HKWTQLQQRIDEFDAQVSKQKEEDL---TKQKKMEEERKSLEETKIKIIEMKTKTEPEKI 11567
Query: 2399 LRNWPKEQ------LLGHFKQSFAGLKREYE---LELQRKTEEIYDLKRLLLNEKNGLHA 2551
+ KE+ + K+ +K + E E+ + +++ D K+++ EK L
Sbjct: 11568 KKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEK 11627
Query: 2552 XXXXXXXXXXXXVAEITGKFEKVLQEN-------------KLLPVEEVQRYKMLCVLKEE 2692
E + K+ Q + + L VE ++ K + + KEE
Sbjct: 11628 MKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEE 11687
Query: 2693 L-----------------QSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHL 2821
L ++K+ + + IKE D K K + LK+ H ++E
Sbjct: 11688 LDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHLRKEKEE 11743
Query: 2822 LKHI---------ADLEAGITD-----------REIMTSVCSDVLTALFVEMVREKEFSL 2941
++ + DLE TD R+++ ++ R EF
Sbjct: 11744 MRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDA 11803
Query: 2942 SLA-TKEQETVNQKQM-SLRKMLED-KDKLLCLVGEENKEHKRQIAILEKLKEETENNPG 3112
++ KE++ QK+M RK LE+ K K++ + + E ++ EK KEE E
Sbjct: 11804 QVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKK----EKEKEEEEVMRA 11859
Query: 3113 RVFLQSEE-----------REKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEK 3259
+V ++ EE R +I+ +++ L+ + E+ K D++ S+I R++ E+
Sbjct: 11860 KVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEE 11919
Query: 3260 LNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDL 3439
+L + ++ + E++ EEL E +K + + DL
Sbjct: 11920 ERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDL 11979
Query: 3440 LIKEKEEL---NERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDL 3610
LI+ K EL NER+ + ++++ L E E++ ++S TR Q E +
Sbjct: 11980 LIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSITEETRRQKEDLEKM 12039
Query: 3611 LNSLTEEHADLKKQ---FLSATEELQSKERDLEVAMTE----TKFLKEKLLVSDENLKE 3766
+ E+ DL+ Q EE+ K + L+ + E KE+ L ++ +KE
Sbjct: 12040 STHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKE 12098
Score = 107 bits (266), Expect = 5e-20
Identities = 223/1154 (19%), Positives = 456/1154 (39%), Gaps = 85/1154 (7%)
Frame = +2
Query: 596 KKIEDLNHKIWSLEETLQYKEEVILSSHETIS-ERDRLLKDFIHEKDLMQQ-RAQETEQK 769
K IE +I E L+ ++ + S +T+ ER L K KDL +Q +Q + +
Sbjct: 2603 KDIETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHE 2662
Query: 770 LASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIV-E 946
+ + + +LE+ + LS K+ +L+ + DCF +++ D +++EE+++Q E
Sbjct: 2663 IQLAEIQKEREILEQLKLTLSKQKE-DLEKER----DCFEKEKA-DISLREELQEQSERE 2716
Query: 947 TIYVTQIQELGEEHDLLR--------LESAKYQDEI---QSLKDECHAKEMSKQAEISKL 1093
I T+++ E +L + LE+ + Q +I + K E E+ K+AE ++
Sbjct: 2717 GIGKTRVRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEK 2776
Query: 1094 SHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSE 1273
E +N E + + N +++ ++R++ + L S D L E
Sbjct: 2777 QRRDIEKDRRNNEEMVIKLQ---NEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKE 2833
Query: 1274 -------------CNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERG-- 1408
K E + +++ SK K++LE+ER
Sbjct: 2834 RFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCF 2893
Query: 1409 -------KISENLERISKLQKMNN-------ELAERSKSQNSIXXXXXXXXXXXXXXXXX 1546
+SE+L+ S+ + ++N E+ E K++ ++
Sbjct: 2894 EKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDE 2953
Query: 1547 XXXVVNM-------AFGSKLEELTDQINI--FNSVIDKKEAEVSGHLDTISSLQTVLSNQ 1699
+ + A +KLE ++ N+ + + K V + + Q VL N
Sbjct: 2954 RDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKKDRENVESLAEELGRKQVVLENM 3013
Query: 1700 KFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKN 1879
+ E E +K +S + E+++ + V + K D + L KN
Sbjct: 3014 QIETEMQRKANESNKQMQERVLIELKKTVTDIAGA----------KEDLENQLLEEREKN 3063
Query: 1880 IQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVH--DDEFDAER 2053
Q + E+ + + K+ + D+V + + +A+++ DE +A R
Sbjct: 3064 KVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQLRLREVELEQLQALIYRQQDEIEANR 3123
Query: 2054 IALLNELKSLH-QDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKS 2230
A++NE L Q E+ + + V + + Y S KD + +
Sbjct: 3124 KAIINEKYRLEGQKTEIDRLQREVNQM----------MEYAS------KDRANLEKEKSE 3167
Query: 2231 RALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNW 2410
++H D+ G I EE+ + + D + L
Sbjct: 3168 MIAQKHQM-----------DIELNKERGLI------EERTQMLNTYEKEMDQKRTALEVE 3210
Query: 2411 PKEQLLGHFKQSFAGLK---REYELELQRKTEEIYDLKRLLLNEKNGLH--AXXXXXXXX 2575
KE L + KQ+ K ++ ++ELQR+ ++I LK NE+ L A
Sbjct: 3211 MKE--LKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKD 3268
Query: 2576 XXXXVAEITGKFE---KVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSN 2746
+AE T + + KVL E+ L +++ K L+ +S+ K+ + DS
Sbjct: 3269 DLAHLAEDTKRKDDEMKVLHESALADIQKE---------KCNLEQMRESMFKQNEMIDSE 3319
Query: 2747 SK--VLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMV 2920
K +L E ++ + Q E K I + +R MT D++T L +
Sbjct: 3320 KKKMILREDKLQQMQAEINRQQTEMDTKKSIIE-----NERAAMTKKNQDLMTEL-TKQS 3373
Query: 2921 REKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETE 3100
+ E + E+E + + L+K +E+ + L ++ ++ E LK++ E
Sbjct: 3374 EDVEIQMKEVLTEKELLESDRKLLKKDVENLQQKLLIIESDS----------ESLKQDRE 3423
Query: 3101 NNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRC 3280
L E+E +++ K L +E E++K + Q++ ++ + + +K + L+
Sbjct: 3424 -------LLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQK 3476
Query: 3281 MXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEEL-----------------KNE 3409
M LD ++ E++N +EL ++E
Sbjct: 3477 MNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLKQSE 3536
Query: 3410 IEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQ 3589
++K+ T+++ +I+ + ++L ++ ME+++ + ++ + +Q L+ + Q
Sbjct: 3537 LDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQ 3596
Query: 3590 TEKYRDLLNSLTEEHADLKK---QFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENL 3760
+ + + N L + +L++ + EE+Q++ + LE E K KE E+
Sbjct: 3597 KQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESFTHLAEDT 3656
Query: 3761 KEKDLQLRAFEIAN 3802
K++ L ++AN
Sbjct: 3657 KKEQEILDEIKVAN 3670
Score = 107 bits (266), Expect = 5e-20
Identities = 244/1167 (20%), Positives = 478/1167 (40%), Gaps = 76/1167 (6%)
Frame = +2
Query: 536 QEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKD 715
QE + +A K E ++ +KIE E +Q +++ + S E + ++ + +K
Sbjct: 7920 QELDLIQAKVVKQKEE-MVKQKIES--------EREIQQEKKKLQRSEEELEDKMQKIKR 7970
Query: 716 FIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNI------ILSLHKQIELQSQNTQSL 877
+ E L+Q ET+ K DN+M + ++D + + S K++E+ +
Sbjct: 7971 EMIELKLLQD---ETDGKRKDVDNKMRQVARKRDELEKMKADVESASKKLEVDRVMLNT- 8026
Query: 878 DCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDL------LRLESAKYQDEIQSL 1039
RDE+E + + + +++ + +LGE+ + L E+ K S
Sbjct: 8027 ---ERDELERIKTESQRATEHMQSHAEERAGDLGEKEPVNTRIQRLIQEAEKASKMAWST 8083
Query: 1040 KDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTA-EIYENTFRELGDQISQLRNDMY 1216
K H EM Q E+S ++E M++N++ + E T R + D++ R +
Sbjct: 8084 K---HEPEMRMQREVSVEEESVERQDMSANMQRMILEIEHARETLRGMKDEVQAARKE-- 8138
Query: 1217 SKNSYIDSLASRIDFLSSECN--KLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDE 1390
S ++++ +++FL+ + N K EQ S +M S+ +++
Sbjct: 8139 --RSELENM--KLEFLTMKKNMEKTYEQQNDEIQKEKQQIE-------SSKMLLSRERND 8187
Query: 1391 LEEERGKISENLERISKLQKMN----NELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXV 1558
LE+ R + E ++I L K NEL ER K+ +
Sbjct: 8188 LEQNRADL-ERQKQIMALDKQKLLAENELLEREKAD--VIKIIENLESLREEATRERATE 8244
Query: 1559 VNMAFGSKLEELTDQINIFNSVIDKKEA------EVSGHLDTISSLQTVLSNQKFEIEKS 1720
A EEL ++ S+ D +EA E+ +D + L+ L Q+ E++K+
Sbjct: 8245 TAQATRRDSEELMQKMEAL-SMEDFQEASKNQMVELKRQIDKLIELKADLLQQQTELKKT 8303
Query: 1721 QKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAV 1900
+ L+ +EK +R L H+ D +T + IQ Q
Sbjct: 8304 KADLKQQMDDLEK-----------------TRSEILKHEKDTDSKTRELELIEIQRQ--- 8343
Query: 1901 SQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALL---NE 2071
K++LE I L L ++L + E V+ + D + ++ +E
Sbjct: 8344 ----------KDDLETRIQKLTLEKRDLEVL-----RSEIVLEKKDLDQKMKQVIRKRDE 8388
Query: 2072 LKSLHQDL-----ELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQ-----EGKDGEASDVQ 2221
++ + D+ E+ + + ++ L NNV + H F L++ E ++ A+D++
Sbjct: 8389 MEKIRSDIANATEEINRERQELEILRNNVQSAR---HDFELLLERTANLEDEESAATDIE 8445
Query: 2222 G------KSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETAD 2383
K R + R+ G+ R K + VE +EK++
Sbjct: 8446 RLVLEVVKIREMVRNLKGEMERRMEKSK-----------VE---IDEKEIFK-------- 8483
Query: 2384 ASDSPLRNWPKEQLLGHFKQSFAGL----------KREYE---LELQRKTEEIYDLKRLL 2524
S ++ + ++ +G +++ GL KRE E EL K +E ++ +L
Sbjct: 8484 ---SEIQRFIQD--IGQIRENLGGLGEEIEKTRRDKRELEKMRAELAEKQQEQESMREML 8538
Query: 2525 LNEKNGLHAXXXXXXXXXXXXVAEITGKF-EKVLQENKLLPVEEVQRYKMLCVLKEELQS 2701
E+ L EI + E V+ + ++ ++Q+YK EELQS
Sbjct: 8539 HKEREELEQLKDEINREKED--VEIRRELVEAVIDKEEMKEFTDIQKYK------EELQS 8590
Query: 2702 KIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSV 2881
+ LL + ++ D + + + + + H ++ + L +L+ G E +
Sbjct: 8591 VTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFELKKG----EQLLEK 8646
Query: 2882 CSDVL--TALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEH 3055
D L VE ++ K+ SL E +N M + + ED DK + +E +E
Sbjct: 8647 QKDELKENGWIVEEIKNKKDSL-------EKIN---MEILRKNEDMDKEKGKLRQEKQEM 8696
Query: 3056 KRQIAILEKLKEETENNPGRVFLQSEE----REKIEEQKRVLDQALQ-------ECEELK 3202
+ L++ +E+ E + ++ + E R +I +K+ LDQ ++ E E+++
Sbjct: 8697 DLFRSELQRQREDLETSIQKLTHEKREMEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIR 8756
Query: 3203 NDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELR 3382
DI N +ID R+E E L ++ S+ D +L R
Sbjct: 8757 FDIANARVEIDGERQELEILRDNVQ-----------------------SARQDFERLVER 8793
Query: 3383 NYNEELKNEIEKKSTDIDLLIKEKEELNERL----AYTQKAMEQKEAVLVEK-LFEGEQK 3547
N E++ E +TDI+ L+ E ++ E + ++ ME+ + + EK +F+ E +
Sbjct: 8794 TANLEVE---ESAATDIERLVLEVVKIREMVRNLKGEMERRMEESKVEIDEKEIFKSEIQ 8850
Query: 3548 ILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFL 3727
L+ + Q RE + + + + ++L+K E+ Q +E E+ E + L
Sbjct: 8851 RLIQDIGQ--IRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQEEESMREILQKEKEEL 8908
Query: 3728 KEKLLVSDENLKEKDLQLRAFEIANSE 3808
++ L D N +++D+++ + E+ SE
Sbjct: 8909 EQ--LKKDINREKEDIEI-SRELVESE 8932
Score = 106 bits (265), Expect = 7e-20
Identities = 223/1183 (18%), Positives = 477/1183 (40%), Gaps = 92/1183 (7%)
Frame = +2
Query: 536 QEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKD 715
+EE + + K E + ++E + +I ++ L +++I E + +++ +
Sbjct: 11575 EEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDL---EKMKSE 11631
Query: 716 FIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNT----QSLDC 883
+ ++ M++ E + K+ D E H + I+ L ++E Q ++ + LD
Sbjct: 11632 IMKQRQQMEEERSELDNKIKQTDLER-HDIENSKEIVQKLMVEVEEQRKDIRLQKEELDI 11690
Query: 884 FRRDEIEDQNIKEEIEKQIV-ETIYVTQI-QELGEEHDLLRLESAKYQDEIQSLKDECHA 1057
R+ ++Q + + + ++ E + ++ +E+ +E + L+ A + E + ++
Sbjct: 11691 ERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEE 11750
Query: 1058 KEMSKQAEISKLSHTLEESIMN-SNLESLFTAEIYENTFR---------ELGDQISQLRN 1207
+ ++ ++ K+S + + + N L E E + E Q+S+ +
Sbjct: 11751 TQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKE 11810
Query: 1208 DMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEM------- 1366
+ +K ++ ++ + +++ + ++A +EM
Sbjct: 11811 EDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQ 11870
Query: 1367 ---QCSKLKDELEEERGKISENLERISK----LQKMNNELA--------ERSKSQNSIXX 1501
Q +++ E++ E+ K++++ + I + L+KM +E+ ERS+ +N I
Sbjct: 11871 IKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQ 11930
Query: 1502 XXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQ 1681
+V ++EE +I +D + +++ D + +
Sbjct: 11931 TYIEKCDIENSKEIVQKLMV------EVEEQKHEIQFQKEELDIERQKIADEQDLLIQNK 11984
Query: 1682 TVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETL 1861
+ L N+ I+ +V+ K ++L E+++ S+ + E L
Sbjct: 11985 SELQNENERIKNINEVI--------KKERETLKEMEAYLEKEKEEMKSITEETRRQKEDL 12036
Query: 1862 RAFVKNI--QNQVAVSQEQHIEHQCKEELEGHIADLV--LNDFSNDILSWSRRKEEAVVH 2029
+I Q Q SQ +E + +EE+ L +++F + S++KEE +
Sbjct: 12037 EKMSTHINEQKQDLRSQRDLLEQE-REEINHKWKQLQQRIDEFDAQV---SKQKEEDLPK 12092
Query: 2030 DDEFDAERIAL------LNELKSLHQDLELLKA---EEAVKSLSNNVGVSTKGIHYF-SQ 2179
+ E +R +L + E+K+ + E+ K EE + + V + K I SQ
Sbjct: 12093 EKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQ 12152
Query: 2180 L--IQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKL 2353
L ++ D E + + + + EDL SE EE+
Sbjct: 12153 LERVRSEMDHEQKKLNDDKKMIEQEK-----------EDLEKMKSEIMKQRQQMEEERSE 12201
Query: 2354 LAILAFETADASDSPLRNWPK--EQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLL 2527
L +T D + N + E+L+ + K+++E++ Q+ E D++R +
Sbjct: 12202 LDKKIKQT-DLEKHDIENSKEIVEKLMVEVE------KQKHEIQFQK---EELDIERQKI 12251
Query: 2528 NEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKI 2707
++ L + E+ E++ +E + L EV K KEE++S I
Sbjct: 12252 ADEQDLLIQNKIEQQNENERIKEMD---EEIKKERETLKEMEVNLQKE----KEEIESVI 12304
Query: 2708 DSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCS 2887
+ + ++ + S + E+ D + + Q + + L+ I + E S
Sbjct: 12305 EETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFE----TTS 12360
Query: 2888 DVLTALFVEMVREKEFSLSLATKEQETV----NQKQMSLRKMLEDKDKLLCLVGEENKEH 3055
++L +E E + L A KE E++ N+K+ L ++ D+ ++NK
Sbjct: 12361 NILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTELEEIEVDQS-------QQNKNV 12413
Query: 3056 KRQIAILEKLKEETENNPGRVFLQSEERE--------KIEEQKRVLDQALQECEELKNDI 3211
+ +LEK +++TE + Q+++ E K E KR LD+ + E+ N+I
Sbjct: 12414 ETMKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEI 12473
Query: 3212 QNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYN 3391
+ D++ +E+++ + K + LD +Q E++N
Sbjct: 12474 LRQRDDLE--KEKEDMMKKW--------------------------NELDGLQKEIQNQK 12505
Query: 3392 ---EELKNEIEKKSTDIDLLIKEKEELNERLAYT--------------QKAMEQKEAVLV 3520
EE+K E+E K +I IKE++ L E L +K +Q E + V
Sbjct: 12506 NEMEEIKCELETKRIEI---IKEQKRLEESLNTVNEERQYLEIVRVDYEKHQQQIEEMRV 12562
Query: 3521 EKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEEL-------Q 3679
+ E ++ L+ + R++ E+ +D++ L +E K + EEL Q
Sbjct: 12563 KTKMERDELDQLM-AKMLMDRKENERSKDMIGLLKKEMEQTKFNLDAQEEELKLEKQKIQ 12621
Query: 3680 SKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSE 3808
++++DLE+ E K ++ E EKD +AFE E
Sbjct: 12622 NEKKDLEMFKAEIKREASEVKTLKEQQLEKD--TKAFEALKEE 12662
Score = 105 bits (263), Expect = 1e-19
Identities = 245/1365 (17%), Positives = 518/1365 (37%), Gaps = 201/1365 (14%)
Frame = +2
Query: 320 KIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGLYVSNV 499
K E L+++++ L+ +L + + ED+ N K+ L E L+
Sbjct: 6071 KEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLREDELWQ--- 6127
Query: 500 VSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLE---ETLQYKEEVIL 670
L + Q+ E ++ +SE + K +EDL HKI SL+ E+L+ E
Sbjct: 6128 -----LQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFE 6182
Query: 671 SSHETISERDRLLKDFIHEKDLMQQRAQETEQKLAS------RDNEMMHMVLE----KDN 820
+ E + + L+ E + ++ Q Q++ +D + ++ ++E KD
Sbjct: 6183 NEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDM 6242
Query: 821 IILSLHKQIELQSQNTQSLDCFRRDEIED--------QNIKEEIEKQIVETIYVTQIQEL 976
++ ++ IE + ++ QS E D +KE++EKQ T+ QIQ+
Sbjct: 6243 VLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTL--AQIQKE 6300
Query: 977 GEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEI 1156
E+ + + + EI+ +++ + KQ E+ +L + I N E EI
Sbjct: 6301 REDLEKMNENITREMHEIKHQEEQMN----QKQDELDQL----KTEIQNLQQELEKEKEI 6352
Query: 1157 YENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXX 1336
+L + S+L + N ++++ + L + +++EQ
Sbjct: 6353 IMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQS 6412
Query: 1337 XXTLKASMEM-------------QCSKLKDELEEERGKISENLERISKLQKMNNELAERS 1477
+L ++M + ++K ELE E I + E +++ ++AE
Sbjct: 6413 RKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEEL 6472
Query: 1478 KSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGH 1657
K + V N + + L++ + I K+ ++
Sbjct: 6473 KKERK-DVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKE 6531
Query: 1658 LDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEK----LVNDSLHEVDSAFCSLNSRFYS 1825
D I + L + EI K Q + +S+IE+ ++ D + ++ S SL+ S
Sbjct: 6532 KDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKD-VEDLQSKIISLDRDAES 6590
Query: 1826 LI---HKVDNSGETLRAFVKNIQNQV----AVSQEQHIEHQCKEELEGHIADLVLND--- 1975
L +N E L+ ++ + + E E Q EE+ + + N+
Sbjct: 6591 LKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQ 6650
Query: 1976 FSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAE-------------- 2113
+ + +K+E D+ D R +L +LK + ++L+ E
Sbjct: 6651 LDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLERE 6710
Query: 2114 -EAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTG----------- 2257
+ + + + + + ++E ++ A +++ K++ L +
Sbjct: 6711 ADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLADLQKE 6770
Query: 2258 ----QAFRE--PPKPEDLYTTYSEGKIVEPH----PTEEKKLLAILAFETADA-SDSPLR 2404
+ RE + ED+ + K+ E TE +K + + E + S+
Sbjct: 6771 KRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAAM 6830
Query: 2405 NWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXX 2584
K+ ++ K K+ ++E+Q K EI K LL N++N L
Sbjct: 6831 IREKQNMMTELK------KKSEDVEMQMK--EILTEKELLHNDRNLLKKDVEDLQQKLMS 6882
Query: 2585 XVAEITG-KFEKVLQEN----------------------KLLPVEEVQRYKMLCVLKEEL 2695
+ K +K EN KL E QR + ++
Sbjct: 6883 IERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKE 6942
Query: 2696 QSKIDSLLKEIKEK-----DSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITD 2860
+ +I++L++EIK+K +S +++ EK + +S D + +S K ++E + +
Sbjct: 6943 REEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRS-DLEKAKSQTFKQNKNIEIALAE 7001
Query: 2861 REIMTSVCSDVLTALFVEMVR--EKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLV 3034
+ + + + + ++ +++ + LA +E E ++ +++ E KD LL +
Sbjct: 7002 IQQKRNALEKMSKEISRDRMKLEDEKKEIQLAREELERMHG---DMQRQQEAKDHLLSGI 7058
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGR-----------VFLQS----------------- 3130
+E+ K + I+ + + + P R VF+Q
Sbjct: 7059 TDESLLKKSEAEIVLQPSQVDKAKPARKTEISDSDKQPVFVQQMPEMDLKDALKKDFESE 7118
Query: 3131 -------------------------EEREKIEEQKRVLDQALQECEELKNDIQNKHSDID 3235
+E +K+++ + L + + E+ K D+QN+ +D
Sbjct: 7119 KLDLPKVKDVLPQDQQMKLEQKLIEDEMDKLKQMRAELQKEADQIEKKKQDMQNERQKLD 7178
Query: 3236 SL-------REEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNE 3394
+ R E+LN+++ ++ + ++ E+ N+
Sbjct: 7179 DMAARLQEERRTNERLNEEINIQKVNQQKQATAFQME-------KTDFERIKTEIDQANK 7231
Query: 3395 ELKNEIEKKSTDIDLLIKEKEELNERLAYTQK-------------AMEQKEAVLVEKLFE 3535
EL ++ EK I + KE+E L E A K + E + A L E + +
Sbjct: 7232 ELADQQEKNKKTITEMQKERETLEEMRANISKQVETITNENKSLSSRESELAKLQEDILQ 7291
Query: 3536 GEQKILLLESS---QSATREQTEKYRDLLNSLTEEHADLKKQFLSATE----ELQSKERD 3694
+Q++ L+++ + +Q + DLL ++ D K ++ E E+ ++ R+
Sbjct: 7292 QQQEMDELKNTIMMEMCQLDQRQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQTRN 7351
Query: 3695 LEVAMTETKFLKEKL------LVSDENLKEKDLQLRAFEIANSEK 3811
++ M K KE L +++L EK+ +L + +++K
Sbjct: 7352 IKSDMVSLKMEKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDK 7396
Score = 104 bits (259), Expect = 3e-19
Identities = 222/1208 (18%), Positives = 484/1208 (40%), Gaps = 43/1208 (3%)
Frame = +2
Query: 326 AETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGLYVSNVVS 505
+E + ME + TLK L +D + ++E+ K+ L+ + +G+ V
Sbjct: 10308 SEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNV----- 10362
Query: 506 DAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHET 685
Q++E K + E +N K +I + ++ ++E L++ +
Sbjct: 10363 ----------QKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEEDLTNQKK 10412
Query: 686 ISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQN 865
+ E + L++ ++ K + + E E H + +K + +L +QI + +
Sbjct: 10413 MEEERKCLEE-VNGKIIEMKTKAELEH----------HEINQKIEELQTLQEQIMKEKEK 10461
Query: 866 TQSLDCFRRDEIED-QNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLK 1042
+++ + E ED IK E+ ++ E + + ++L ++ ++ E +++++ +K
Sbjct: 10462 AEAMTIKLKMEREDLDQIKSELVREKTEVDH--EQKKLNDDIKMIEQE----KEDLEKMK 10515
Query: 1043 DECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSK 1222
E ++ + E S+L + ++++ + + + + EI E E+ +Q +++
Sbjct: 10516 SEIMTQKQEMEKERSELDNKIQQTDLEKH-DIEKSKEIVEKLMFEVEEQRHEIQLQKEEL 10574
Query: 1223 NSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELE-- 1396
+ +A D L ++LQ + TLK ME K K+E++
Sbjct: 10575 DIERQKIADEQDLLIQNKSELQNENERIRNINEVIKKERETLK-EMEAHLEKEKEEMKSI 10633
Query: 1397 -EERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAF 1573
EE + E+LE++S K N+ + K ++ +
Sbjct: 10634 TEETRRQKEDLEKMSTDIKEQNQ--DLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQVS 10691
Query: 1574 GSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHI 1753
K E+LT Q + ++K E +T + + + + + E K +K + E +
Sbjct: 10692 KQKEEDLTKQKEMKE---ERKSLE-----ETKARIIEMKTKAELEDIKKEKEKEEEEEEM 10743
Query: 1754 EKLVNDSLHEVDSAFCSLNSRFYSLIH---KVDNSGETLRAFVKNIQNQVA--VSQEQHI 1918
V E+D L + H K+++ + + +N++ + + Q Q +
Sbjct: 10744 RVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKSEIMKQRQQM 10803
Query: 1919 EHQCKEELEGHIADLVLN--DFSND-------ILSWSRRKEEAVVHDDEFDAERIALLNE 2071
E + + ELE I + D N ++ +K E +E D ER + +E
Sbjct: 10804 EEE-RSELENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADE 10862
Query: 2072 LKSLHQDL-ELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRH 2248
L Q+ EL E +++L+ + + + +++ K+ E V ++R L+
Sbjct: 10863 QDLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKE-EIKSVSEETRRLKED 10921
Query: 2249 STGQAFREPPKPEDLYTTYSEGKIVEPHPTEE----KKLLAILAFETADASDSPLRNWPK 2416
+ + +DL ++ ++E E K+L + A S ++ PK
Sbjct: 10922 LEKMSTDVNKQNKDLM---NQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPK 10978
Query: 2417 EQLLGHFKQSFAGLKREY-ELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVA 2593
E+ + ++S K E++ + + EEI K E+ +
Sbjct: 10979 EKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELY 11038
Query: 2594 EITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLS 2773
+I + E+V E + KM+ KE+L+ ++K+ ++ + L K+
Sbjct: 11039 QIKSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKI- 11097
Query: 2774 DALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLAT 2953
++++L KH D+E +++ L VE V E+ + L
Sbjct: 11098 -----------QQTNLEKH--DIEKS-----------KEIVEKLMVE-VEEQRKDIQLQK 11132
Query: 2954 KEQETVNQKQMSLRKML-EDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQS 3130
+E + QK + +L ++K KL E++R + E++K+E E
Sbjct: 11133 EELDIERQKIADEQNLLVQNKAKL-------QNENERIKKVDEEIKKERET-------LR 11178
Query: 3131 EEREKIEEQKRVLDQALQECEELKNDIQNKHSDI-----------DSLREEQEKLNKQLR 3277
E ++++K L ++E + K D++ +DI D L +E+E++N ++
Sbjct: 11179 EMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREEINHEMT 11238
Query: 3278 CMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEEL-KNEIEKKSTDID------ 3436
+ +D ++ E+L K E+E++ ++
Sbjct: 11239 ---------------------QLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARI 11277
Query: 3437 LLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLN 3616
+ +K K EL E + ++ E++ V+VE +++ ++S R + + + LN
Sbjct: 11278 IEMKTKAELQEIMQEKEEEDEEEMRVIVEM---EREELNQIKSELKRVRSEIDHEQKKLN 11334
Query: 3617 SLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEI 3796
D KK E+L+ + ++ MT+ + ++E+ D +K+ DL+ +I
Sbjct: 11335 -------DDKKIIEQEKEDLEKMKSEI---MTQRQQMEEERSELDNKIKQTDLE--RHDI 11382
Query: 3797 ANSEKQYQ 3820
NS++ Q
Sbjct: 11383 ENSKEIVQ 11390
Score = 102 bits (255), Expect = 1e-18
Identities = 220/1188 (18%), Positives = 496/1188 (41%), Gaps = 26/1188 (2%)
Frame = +2
Query: 296 DTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVE 475
D +S+ +AE E++ I L++ +L ++ + + E+ + ++ +D +
Sbjct: 1820 DKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIR 1879
Query: 476 SGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYK 655
G+ + + + + ++ A +++ + K I+++ +++ QY
Sbjct: 1880 VGIEKQEITFKDL--------KADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQKERQYM 1931
Query: 656 EEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLAS--RDNEMMHMVLEKDNIIL 829
+ ++ + D + + E+ ++ + E EQ+ + D + EK+NII
Sbjct: 1932 DRLVEEIEKRTKALDEMQMEVDKERQEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQ 1991
Query: 830 SLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLES 1009
+ +I+ +S N E++ +NI +E TI+ EL +EH LR
Sbjct: 1992 A---EIQKESDNL---------ELQSENISKE------RTIF-----ELEKEHLGLRENE 2028
Query: 1010 AKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQ 1189
A+Y+ Q DE K ++ ++ ++ ++ E + TA E T
Sbjct: 2029 AEYK---QKQIDELQNKLRMEKVQVEQMQ--ADKDQQRKKAEYVKTARGRETT------A 2077
Query: 1190 ISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQ 1369
+ + R +M +SL + + + + EQ +K E +
Sbjct: 2078 LEEQRQEM-------ESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKYKE-K 2129
Query: 1370 CSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXX 1549
K ++L+ +R + ++++ ++ E ER K + I
Sbjct: 2130 LDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEI---QKPAVYTETYMLETQ 2186
Query: 1550 XXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKV 1729
VV + +L+E+ +IN S ++K+++ + IS ++ + EK +
Sbjct: 2187 KPVVEKSKTDELDEVRKKINADLSEVEKQKSALVQMNLKISQEESYVKK-----EKDRLK 2241
Query: 1730 LQSFESHIE-KLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQ 1906
LQ E +++ +N +E+D + + L + +D + + +V +++
Sbjct: 2242 LQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMD----------RLEKEKVEITK 2291
Query: 1907 EQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLH 2086
E+ ++ + E++ A S D++ K+E + D + R L EL+ +
Sbjct: 2292 EKQRVNEMQNEVKRKNA-------SVDLI-----KQEVLREQDHIENSREILNRELEKIK 2339
Query: 2087 QDLELLKAE-EAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRAL---RRHST 2254
+ +L E EA+ +G + + +Q+ EA D + + R + RR++
Sbjct: 2340 EKKTILAEEFEALDDKKEMIGKEMQRLGKMKAELQK----EAEDTEKQRRDIDNDRRNNE 2395
Query: 2255 GQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGH 2434
+ + +D+ T+ + E + +K+ L +T + L E +
Sbjct: 2396 EMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLE-SDRDTLEKERFDLEKTKTE--MKD 2452
Query: 2435 FKQSFAGLKREYEL---ELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITG 2605
++ R++E+ E+Q++ E + LK L +K L A+I+
Sbjct: 2453 LEKQLESQSRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEK----ADISL 2508
Query: 2606 KFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSN--SKVLAEKLSDA 2779
+ E Q K E + + ++ +K+E+ + L +KE ++N K + E D
Sbjct: 2509 REELEEQSEK----EGIDKTRVR--IKQEMDELEQTRLNVVKELENNELQKQIIEDERDK 2562
Query: 2780 LKKSADHAQRES-HLLKHIADLEAGITDREIMT----SVCSDVLTALFVEMVREKEFSLS 2944
+++ Q+E+ K D+E + E M + D+ T+ + +R++E +L
Sbjct: 2563 IEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETS--TDRIRDEEANLR 2620
Query: 2945 LATK----EQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPG 3112
+ + +++T+ +++ L+K + L + +N++H+ Q+A ++K
Sbjct: 2621 VLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQK---------- 2670
Query: 3113 RVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXX 3292
ERE +E+ K L + ++ E+ ++ + + +DI SLREE ++ +++
Sbjct: 2671 -------EREILEQLKLTLSKQKEDLEKERDCFEKEKADI-SLREELQEQSER------- 2715
Query: 3293 XXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELK-NEIEKKSTDIDLLIKEKEELNE 3469
I +D ++ N +EL+ NE++K+ ++ E++++ +
Sbjct: 2716 --------EGIGKTRVRIKKEMDELKQTRLNVVKELENNELQKQ-----IIEDERDKIEQ 2762
Query: 3470 RLAYTQKAME--QKEAVLVEK-LFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHAD 3640
A QK E +K+ +EK E+ ++ L++ + T++ RD E + +
Sbjct: 2763 IKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETSTDRIRD-----EEANLE 2817
Query: 3641 LKKQFLSATEELQSKER-DLEVAMTETKFLKEKLLVSDENLKEKDLQL 3781
++KQ L + + KER DLE TE LK++L + +++ ++QL
Sbjct: 2818 VQKQRLESDRDTLEKERFDLEKTKTEMGNLKKQL---ESQIRQHEIQL 2862
Score = 101 bits (252), Expect = 2e-18
Identities = 227/1221 (18%), Positives = 499/1221 (40%), Gaps = 47/1221 (3%)
Frame = +2
Query: 257 SVTSFIEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLE 436
SVT + + LD S + +T+E + I G L+ + F+L + LLE
Sbjct: 8590 SVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFELKKGEQ----LLE 8645
Query: 437 DIRNTKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLN 616
KD L E+G V EE K + + N + +K ED++
Sbjct: 8646 ---KQKDELK--ENGWIV-----------------EEIKNKKDSLEKINMEILRKNEDMD 8683
Query: 617 HKIWSLEETLQYKEEVILSSHETISERDRL---LKDFIHEKDLMQQRAQETEQKLASRDN 787
+ L Q K+E+ L E +R+ L ++ HEK M+ E + D
Sbjct: 8684 KEKGKLR---QEKQEMDLFRSELQRQREDLETSIQKLTHEKREMEVLRSEIVLEKKDLDQ 8740
Query: 788 EMMHMVLEKDNI------ILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVET 949
+M ++ ++D + I + +I+ + Q + L RD + Q+ +++ E+ + T
Sbjct: 8741 KMKQVIRKRDEMEKIRFDIANARVEIDGERQELEIL----RDNV--QSARQDFERLVERT 8794
Query: 950 IYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSN 1129
+ + + + L LE K ++ +++LK E + + EI +
Sbjct: 8795 ANLEVEESAATDIERLVLEVVKIREMVRNLKGEMERRMEESKVEIDE------------- 8841
Query: 1130 LESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLA---SRIDFLSSECNKLQEQXX 1300
EI+++ + L I Q+R ++ + I++ S ++ + +E + Q++
Sbjct: 8842 ------KEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQE-- 8893
Query: 1301 XXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSK 1480
+ SM K K+ELE+ + I+ E I +++ EL E
Sbjct: 8894 ----------------EESMREILQKEKEELEQLKKDINREKEDI----EISRELVESEI 8933
Query: 1481 SQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHL 1660
+ + + +L+ +T+++ +++ ++V +
Sbjct: 8934 YEGEVKGFTDV-----------------QKYKEELQIVTEELLTKKRNLEQLNSDVQHLM 8976
Query: 1661 DTISSLQTVLSNQKFEIE----KSQKVLQSFESHIEKLVNDS--LHEVDSAFCSLNSRFY 1822
T+ + +K E+E + QK Q E +KL + + E++ +L S
Sbjct: 8977 QTLEEVDIQYIKKKAELEHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINM 9036
Query: 1823 SLIHK---VDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDIL 1993
++ K ++ E LR + + Q Q ++E+E L++ +
Sbjct: 9037 EILQKREDMEKEKENLRREKQETELFRGELQRQ------RDEVESSRQALIMEKDQFKLK 9090
Query: 1994 SWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYF 2173
+R E + + E L+++ DLE +A+ A +SL++ + K
Sbjct: 9091 IDHQRNEMSAAFEKEH--------KRLENMENDLENQRAKLA-ESLNDAAKMEQKLQQMK 9141
Query: 2174 SQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKL 2353
++L +E + E K+ ++ + R+ + +I + H +KK
Sbjct: 9142 NELNKEKEQVEEMKQMVKTERVKIEQEKEEMRKQTQ-----------EIEDGHEKLQKKT 9190
Query: 2354 -LAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELE---LQRKTEEIYDLKRL 2521
+A + A++ L++ + L +Q E E + L R + E+ D K
Sbjct: 9191 EIADKLLQDANSESDRLKDLSMK--LQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIR 9248
Query: 2522 LLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQS 2701
L N+++ + + K E++++E + L + +Q+ + + K ++++
Sbjct: 9249 LKNDRDAYEKD-----------MTHLELKREELVRETEDLERKILQQREQDEMAKRDIEN 9297
Query: 2702 KIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSV 2881
+ ++L E+ + D +L ++ A + H++R+ LL L+ + +E
Sbjct: 9298 QTEAL--EVMKVD----ILKKRNEFAKEMENVHSERQKLLL-----LQGALQSQE----- 9341
Query: 2882 CSDVLTALFVEMVREKEFSLSLATKEQ---------ETVNQKQMSLRKMLEDKDKLLCLV 3034
S++ +F+E +K + A E+ ETV +Q RK++E+ +
Sbjct: 9342 -SELENRVFME--EQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQR----E 9394
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVFLQSE----EREKIEEQKRVLDQALQECEELK 3202
E+ + K QI E+ K++ +N + Q E E+ +E++K L++ E +E++
Sbjct: 9395 KEQLEISKNQI---EQEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQ 9451
Query: 3203 NDIQNKHSDIDS----LREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQ 3370
N I+ + D+++ + E++++ ++ R + + +
Sbjct: 9452 NAIRKEREDLENCWVEIEGEKKRMEEETRRLEMHR------------------EEIKKVD 9493
Query: 3371 LELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKI 3550
EL+ E +++ EK + ++ L++ K E+ +K ++ + ++
Sbjct: 9494 SELQKSRENIESREEKINNKMEELLQMKVEMGRTKEEIEKESQRLQDATID--------- 9544
Query: 3551 LLLESSQSATREQTEKYRDLLN-SLTEEHADLKKQFLSAT----EELQSKERDLEVAMTE 3715
LE++++ + Q +K+ D+++ + E+ ++K Q T EE++ K +DLE+ M +
Sbjct: 9545 --LENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQLDKETKRLSEEIELKVKDLEMEMAD 9602
Query: 3716 TKFLKEKLLVSDENLKEKDLQ 3778
K K++ + + L EK+ Q
Sbjct: 9603 MKRQKQE-IEDTKGLLEKEKQ 9622
Score = 99.8 bits (247), Expect = 9e-18
Identities = 238/1239 (19%), Positives = 502/1239 (40%), Gaps = 68/1239 (5%)
Frame = +2
Query: 302 RKSLETKIAE-TLERMEIHEGDTANTLKNMNFD------------LGQDNPGVPGLLEDI 442
+ LET+I + TLE+ ++ + L+ + D + + + E+I
Sbjct: 8344 KDDLETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANATEEI 8403
Query: 443 RNTKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNK-KIEDLNH 619
+ L+ + + + + + +L + ++EE AA D E +L KI ++
Sbjct: 8404 NRERQELEILRNNVQSARHDFELLLERTANLEDEES----AATDIERLVLEVVKIREMVR 8459
Query: 620 KIWSLEETLQYKEEVILSSHETI-SERDRLLKDFIHEKDLMQQRAQETEQ-KLASRDNEM 793
+ E K +V + E SE R ++D ++ + +E E+ + R+ E
Sbjct: 8460 NLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEK 8519
Query: 794 MHMVL-EKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQ 970
M L EK S+ + + + + + L +DEI + EI +++VE V +
Sbjct: 8520 MRAELAEKQQEQESMREMLHKEREELEQL----KDEINREKEDVEIRRELVEA--VIDKE 8573
Query: 971 ELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQ---AEISKLSHTLEESIMNSNLESL 1141
E+ E D+ KY++E+QS+ +E K+ +++ L T+EE + +
Sbjct: 8574 EMKEFTDI-----QKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKR- 8627
Query: 1142 FTAEIYENTFR-ELGDQISQLRNDMYSKNSYI-DSLASRIDFLSSECNKLQEQXXXXXXX 1315
AE+ F + G+Q+ + + D +N +I + + ++ D L K+ +
Sbjct: 8628 --AELEGIGFELKKGEQLLEKQKDELKENGWIVEEIKNKKDSLE----KINMEILRKNED 8681
Query: 1316 XXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSI 1495
K M++ + EL+ +R E+LE + +QK+ +E E ++ I
Sbjct: 8682 MDKEKGKLRQEKQEMDL----FRSELQRQR----EDLE--TSIQKLTHEKREMEVLRSEI 8731
Query: 1496 XXXXXXXXXXXXXXXXXXXXVVNMAFG------------SKLEELTDQINIFNSVIDKKE 1639
+ + F +LE L D + ++
Sbjct: 8732 VLEKKDLDQKMKQVIRKRDEMEKIRFDIANARVEIDGERQELEILRDNVQSARQDFERL- 8790
Query: 1640 AEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSA--FCSLNS 1813
E + +L+ S T + E+ K ++++++ + +E+ + +S E+D F S
Sbjct: 8791 VERTANLEVEESAATDIERLVLEVVKIREMVRNLKGEMERRMEESKVEIDEKEIFKSEIQ 8850
Query: 1814 RFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLV------LND 1975
R I ++ + L+ ++N + + ++ E + K++ E + +++ L
Sbjct: 8851 RLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQEEESMREILQKEKEELEQ 8910
Query: 1976 FSNDILSWSRRKEEAVVHDDEFDAE----RIALLNELKSLHQDLELLKAEEAVKSLSNNV 2143
DI +R KE+ + + ++E + +++ ++L+++ E K N+
Sbjct: 8911 LKKDI---NREKEDIEISRELVESEIYEGEVKGFTDVQKYKEELQIVTEELLTKK--RNL 8965
Query: 2144 GVSTKGIHYFSQLIQEGKDGEASDVQG-KSRALRRHSTGQAFREPPKPEDLYTTYSEGKI 2320
+ + Q ++E D+Q K +A H T + + E E
Sbjct: 8966 EQLNSDVQHLMQTLEE------VDIQYIKKKAELEHITSEIQKREQILEKQKKKLEENGW 9019
Query: 2321 VEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYEL---ELQRK 2491
+ EE +++ + T ++ + + K + + K++ K+E EL ELQR+
Sbjct: 9020 I----IEEIEMMKV----TLESINMEILQ--KREDMEKEKENLRREKQETELFRGELQRQ 9069
Query: 2492 TEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKM 2671
+E+ ++ L+ EK+ +F+ + QR +M
Sbjct: 9070 RDEVESSRQALIMEKD----------------------QFKLKIDH---------QRNEM 9098
Query: 2672 LCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAG 2851
++E +++++ +++ + + LAE L+DA K Q ++ L K +E
Sbjct: 9099 SAAFEKE-HKRLENMENDLENQRAK---LAESLNDAAKMEQKLQQMKNELNKEKEQVEE- 9153
Query: 2852 ITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCL 3031
++ V++ +EKE + T+E E ++K L+K E DKLL
Sbjct: 9154 ----------MKQMVKTERVKIEQEKE-EMRKQTQEIEDGHEK---LQKKTEIADKLLQD 9199
Query: 3032 VGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEE----L 3199
E+ K L+ +++ E ++E +KR LD+ +E ++ L
Sbjct: 9200 ANSESDRLKDLSMKLQMQRQDIEKT----------NTEMETKKRSLDRMSRELQDDKIRL 9249
Query: 3200 KNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLEL 3379
KND D+ L ++E+L ++ + +L+ L+
Sbjct: 9250 KNDRDAYEKDMTHLELKREELVRE-------------------------TEDLERKILQQ 9284
Query: 3380 RNYNEELKNEIEKKSTDIDLL-----------IKEKEELN---ERLAYTQKAMEQKEAVL 3517
R +E K +IE ++ ++++ KE E ++ ++L Q A++ +E+ L
Sbjct: 9285 REQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQESEL 9344
Query: 3518 VEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDL 3697
++F EQK L + +TE+ R L ++E + ++ EELQ ++ L
Sbjct: 9345 ENRVFMEEQKHL------KQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQREKEQL 9398
Query: 3698 EVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQ 3814
E++ + + K+ L NL E+ L+ E AN E +
Sbjct: 9399 EISKNQIEQEKKDLQNMKSNL-ERQLESLRHEKANVEDE 9436
Score = 99.0 bits (245), Expect = 1e-17
Identities = 237/1220 (19%), Positives = 485/1220 (39%), Gaps = 57/1220 (4%)
Frame = +2
Query: 305 KSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGL 484
K + +IAE L+++ GD +N +L ++ + + + ++ +D+ + L
Sbjct: 1710 KKSQDEIAEQLKQV----GDMMQFTQNEKDNLDRERAAI--IEQKLQMERDMTHLLNREL 1763
Query: 485 YVSNVVSDAVLNGVVSAQE------------EEFKEALAAKDSENFLLNKKIEDLNHKIW 628
+V VLN ++ E+ K L + E L + I + K+
Sbjct: 1764 ESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLE 1823
Query: 629 SLEETLQYKEEVILSSHETISERDRLLKDFIH---EKDLMQQRAQETEQKLASRDNEMMH 799
S+ +TL E + +T++E+ +L + E+D + A+ET++K D + +
Sbjct: 1824 SVLQTLAEDTEKLRI--DTLAEKQKLEDAAVELQKERDEIMNIAEETKRK--REDVDKIR 1879
Query: 800 MVLEKDNIILS-----LHKQIELQSQNTQSLDCFRRD--EIEDQNIKEEIEKQIVETIYV 958
+ +EK I L K+ + Q++ ++D ++D ++ + E+Q ++ + V
Sbjct: 1880 VGIEKQEITFKDLKADLQKEAAIVENQRQAV---QKDIQNVKDMEVQIQKERQYMDRL-V 1935
Query: 959 TQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSK------------------QAEI 1084
+I++ + D +++E K + E++S +DE +E SK QAEI
Sbjct: 1936 EEIEKRTKALDEMQMEVDKERQEVESKRDELE-QETSKLREDEDEFSRQKEKNNIIQAEI 1994
Query: 1085 SKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLR-NDMYSKNSYIDSLASRIDF 1261
K S LE + + N+ E T EL + LR N+ K ID L +++
Sbjct: 1995 QKESDNLE--LQSENISK-------ERTIFELEKEHLGLRENEAEYKQKQIDELQNKLRM 2045
Query: 1262 LSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISK 1441
+ ++Q +K + + + L+++ +E + E E + K
Sbjct: 2046 EKVQVEQMQADKDQQRKKAEY-------VKTARGRETTALEEQ-RQEMESLREEYENVEK 2097
Query: 1442 LQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNS 1621
+K NE E +S+ + E+L Q +F
Sbjct: 2098 QKKHVNEQKELFESRMKSLEMENEAMKKYKEK-----------LDKEYEDLQFQRQLFEK 2146
Query: 1622 VIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFC 1801
I + E+ + I + L QK + +L++ + +EK D L EV
Sbjct: 2147 EIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDEV----- 2201
Query: 1802 SLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFS 1981
+ + + +V+ L +Q + +SQE+ + K+ L+ L N+ +
Sbjct: 2202 --RKKINADLSEVEKQKSAL------VQMNLKISQEESYVKKEKDRLK-----LQENEQN 2248
Query: 1982 NDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQD-LELLKAEEAVKSLSNNVGVSTK 2158
+ + ++ E E + ++ L N + L ++ +E+ K ++ V + N V
Sbjct: 2249 MQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITKEKQRVNEMQNEVKRKNA 2308
Query: 2159 GIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPT 2338
+ Q + +D ++ L R E
Sbjct: 2309 SVDLIKQEVLREQD----HIENSREILNR--------------------------ELEKI 2338
Query: 2339 EEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKR 2518
+EKK + FE D K++++G Q +K E LQ++ E+ +R
Sbjct: 2339 KEKKTILAEEFEALD---------DKKEMIGKEMQRLGKMKAE----LQKEAEDTEKQRR 2385
Query: 2519 LLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQ 2698
+ N++ V ++ + + + + EE L V K+ L+
Sbjct: 2386 DIDNDRRN-----------NEEMVIKLQNEKKDIETSTDRIRDEEAN----LRVQKQRLE 2430
Query: 2699 SKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTS 2878
S D+L KE + + + + L+K Q ES +H L +REI
Sbjct: 2431 SDRDTLEKERFDLEKTKTEMKD-----LEK-----QLESQSRQHEIQLVEIQKEREI--- 2477
Query: 2879 VCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQ--MSLRKMLEDKDKLLCLVGEENKE 3052
L L + + ++KE KE++ +++ +SLR+ LE++ + + +
Sbjct: 2478 -----LEQLKINLSKQKED----LEKERDCFEKEKADISLREELEEQSEKEG-IDKTRVR 2527
Query: 3053 HKRQIAILEKLK----EETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNK 3220
K+++ LE+ + +E ENN + + +ER+KIE+ K L + ++ E+ + DI+N
Sbjct: 2528 IKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIEND 2587
Query: 3221 HSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEEL 3400
+ + + + + K + L+ + +L+ N E+
Sbjct: 2588 RRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEM 2647
Query: 3401 KN-----EIEKKSTDIDLL-IKEKEELNERLAYTQKAMEQKEAVLVEK-LFEGEQKILLL 3559
K+ E + + +I L I+++ E+ E+L T +QKE + E+ FE E+ + L
Sbjct: 2648 KDLEKQLESQNRQHEIQLAEIQKEREILEQLKLT--LSKQKEDLEKERDCFEKEKADISL 2705
Query: 3560 --ESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKE 3733
E + + RE K R + +E +LK+ L+ +EL++ E ++ E +++
Sbjct: 2706 REELQEQSEREGIGKTR---VRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQ 2762
Query: 3734 KLLVSDENLKEKDLQLRAFE 3793
+ ++ + Q R E
Sbjct: 2763 IKAELQKEAEDTEKQRRDIE 2782
Score = 94.4 bits (233), Expect = 4e-16
Identities = 243/1244 (19%), Positives = 500/1244 (40%), Gaps = 68/1244 (5%)
Frame = +2
Query: 293 LDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTV 472
+ T+ + KI+E + + + + +K +DL Q + D+ + + +
Sbjct: 1646 IKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQ-------MQTDLNRQQKEMQDI 1698
Query: 473 ESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQY 652
++ +++ + + +Q+E ++ D F N+K + +E+ LQ
Sbjct: 1699 QNAVFMEK-------SELKKSQDEIAEQLKQVGDMMQFTQNEKDNLDRERAAIIEQKLQM 1751
Query: 653 KEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILS 832
+ ++ + + + K+ ++EK L++ + + +D E M + LE++
Sbjct: 1752 ERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRDM--QDLEQMKINLEREK---- 1805
Query: 833 LHKQIELQSQNTQSLDCFRRDEIED--QNIKEEIEKQIVETIYVTQIQELGEEHDLLRLE 1006
++++LQ Q+ +D++E Q + E+ EK ++T+ + Q+L + +E
Sbjct: 1806 --EEMQLQRQSIAE----EKDKLESVLQTLAEDTEKLRIDTL--AEKQKLEDA----AVE 1853
Query: 1007 SAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLE-ESIMNSNLESLFTAE--IYENTFRE 1177
K +DEI ++ +E K + ++ K+ +E + I +L++ E I EN +
Sbjct: 1854 LQKERDEIMNIAEETKRK----REDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQA 1909
Query: 1178 LGDQISQLRN---DMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTL 1348
+ I +++ + + Y+D L I+ + +++Q +
Sbjct: 1910 VQKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVD---------------- 1953
Query: 1349 KASMEMQCSKLKDELEEERGKISENLERISKLQKMNNEL-AERSKSQNSIXXXXXXXXXX 1525
K E++ + DELE+E K+ E+ + S+ ++ NN + AE K +++
Sbjct: 1954 KERQEVESKR--DELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKE 2011
Query: 1526 XXXXXXXXXXV---VNMA--FGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVL 1690
+ N A +++EL +++ + +++ +A+ ++T
Sbjct: 2012 RTIFELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTAR 2071
Query: 1691 SNQKFEIEKSQKVLQSFESHIE------KLVNDSLHEVDSAFCSL---NSRFYSLIHKVD 1843
+ +E+ ++ ++S E K VN+ +S SL N K+D
Sbjct: 2072 GRETTALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKYKEKLD 2131
Query: 1844 NSGETL----RAFVKNIQNQVAVSQ--EQHIEHQCKE--------ELEGHIADL---VLN 1972
E L + F K IQ Q ++IE + KE E ++ + V+
Sbjct: 2132 KEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVE 2191
Query: 1973 DFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVS 2152
D L R+K A + + E + +N LK ++ + K ++ +K N +
Sbjct: 2192 KSKTDELDEVRKKINADLSEVEKQKSALVQMN-LKISQEESYVKKEKDRLKLQENEQNMQ 2250
Query: 2153 TKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPH 2332
SQL K E + Q + +R + + + E + T + ++ E
Sbjct: 2251 ------MSQL--NAKQNELDERQAEMEKQKREL--ENVMDRLEKEKVEITKEKQRVNEMQ 2300
Query: 2333 PTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKT------ 2494
++K ++ D + +EQ H + S L RE E ++KT
Sbjct: 2301 NEVKRKNASV---------DLIKQEVLREQ--DHIENSREILNRELEKIKEKKTILAEEF 2349
Query: 2495 EEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKML 2674
E + D K ++ E L AE+ + E ++ + + + +M+
Sbjct: 2350 EALDDKKEMIGKEMQRL-----------GKMKAELQKEAEDTEKQRRDIDNDRRNNEEMV 2398
Query: 2675 CVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLS---DALKKSADHAQRESHLLKHIADLE 2845
L+ E + I++ I+++++N +V ++L D L+K ++ +K DLE
Sbjct: 2399 IKLQNE-KKDIETSTDRIRDEEANLRVQKQRLESDRDTLEKERFDLEKTKTEMK---DLE 2454
Query: 2846 AGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLL 3025
+ + R+ E L KE+E + Q +++L K ED +K
Sbjct: 2455 KQLESQS------------------RQHEIQLVEIQKEREILEQLKINLSKQKEDLEKER 2496
Query: 3026 CLVGEENKEHKRQIAILEKLKEETEN---NPGRVFLQSE-------------EREKIEEQ 3157
+E K I++ E+L+E++E + RV ++ E E E E Q
Sbjct: 2497 DCFEKE----KADISLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQ 2552
Query: 3158 KRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXX 3337
K++++ + E++K ++Q + D + R++ E + M
Sbjct: 2553 KQIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRI 2612
Query: 3338 XXISSNLDSMQLELRNYNEELKNE---IEKKSTDIDLLIKEKEELNERLAYTQKAMEQKE 3508
+NL ++ L + + L+ E ++K +T++ L K+ E N R Q A QKE
Sbjct: 2613 RDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQN-RQHEIQLAEIQKE 2671
Query: 3509 AVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKE 3688
++E+L K+ L S +E EK RD +E AD +S EELQ +
Sbjct: 2672 REILEQL-----KLTL-----SKQKEDLEKERDCFE---KEKAD-----ISLREELQEQS 2713
Query: 3689 RDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQYQ 3820
+ T + KE + LK+ L + E+ N+E Q Q
Sbjct: 2714 EREGIGKTRVRIKKEM-----DELKQTRLNV-VKELENNELQKQ 2751
Score = 94.0 bits (232), Expect = 5e-16
Identities = 221/1220 (18%), Positives = 488/1220 (40%), Gaps = 53/1220 (4%)
Frame = +2
Query: 284 DGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLL 463
DG + + ++ E+L + +GD L+ M D + + + + + + L
Sbjct: 10130 DGKRNEINKEQQRLEESLRAINEEKGD----LEIMRADYEKQEQQIEEMRVEAKMERKEL 10185
Query: 464 DTVESGLYVSNVVSD---AVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSL 634
D ++S L D LN + E+E + L SE +++ED
Sbjct: 10186 DQIKSELEKDKTEIDYEWKKLNNDRNMIEKE-RNDLEKMKSELMTQRQQMED-------- 10236
Query: 635 EETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEK 814
+ E+ E +E+D++ K+ K+++++ E E++ + + LE+
Sbjct: 10237 -----ERSELDQKIKEANTEKDKIEKN----KEIVERLMAEVEEQRNDFKLKKEELALER 10287
Query: 815 DNII----LSLHKQIELQSQNTQ----------SLDCFRRDEIEDQNIKEEIEKQIVETI 952
NI+ L + ELQ+++ Q + + E Q K+EI+ I ET
Sbjct: 10288 QNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETS 10347
Query: 953 YVTQ-IQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSN 1129
+ ++++ ++ + E +D ++ ++E + K Q I + + + +
Sbjct: 10348 RQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQ-KEED 10406
Query: 1130 LESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXX 1309
L + E E+ +I +++ ++ I+ + L + K +E+
Sbjct: 10407 LTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAMT 10466
Query: 1310 XXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISK----LQKMNNELA--- 1468
+K+ + + K E++ E+ K++++++ I + L+KM +E+
Sbjct: 10467 IKLKMEREDLDQIKSELVRE----KTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQK 10522
Query: 1469 -ERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAE 1645
E K ++ + V + F ++EE +I + +D + +
Sbjct: 10523 QEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMF--EVEEQRHEIQLQKEELDIERQK 10580
Query: 1646 VSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYS 1825
++ D + ++ L N+ I +V+ K ++L E+++ S
Sbjct: 10581 IADEQDLLIQNKSELQNENERIRNINEVI--------KKERETLKEMEAHLEKEKEEMKS 10632
Query: 1826 LIHKVDNSGETLRAFVKNI--QNQVAVSQEQHIEHQCKEELEGHIADLV--LNDFSNDIL 1993
+ + E L +I QNQ + Q +E + KE++ L +++F +
Sbjct: 10633 ITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQE-KEDINHEWTQLQQRIDEFDAQV- 10690
Query: 1994 SWSRRKEEAVVHDDEFDAERIAL------LNELKSLHQDLELLKAEEAVKSLSNNVGVST 2155
S++KEE + E ER +L + E+K+ +LE +K E+ + + V
Sbjct: 10691 --SKQKEEDLTKQKEMKEERKSLEETKARIIEMKT-KAELEDIKKEKEKEEEEEEMRVKV 10747
Query: 2156 KGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHP 2335
+ DG+ D + KS R S + E K D + KI+E
Sbjct: 10748 E------------MDGKELD-RIKSELKRERS--EIDHEQKKLND------DKKIIEQEK 10786
Query: 2336 TEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLK 2515
+K+ K +++ +Q E EL+ K ++ Y K
Sbjct: 10787 QNLEKM--------------------KSEIMKQRQQM-----EEERSELENKIKQTYIEK 10821
Query: 2516 RLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENK---LLPVEEVQRYKMLCVLK 2686
+ N K EI K ++E K EE+ + +
Sbjct: 10822 CDIENSK-------------------EIVQKLMVEVEEQKHEIQFQKEELDIERQKIADE 10862
Query: 2687 EELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDRE 2866
++L + S L+ E+ N + +K + LK+ H +++ +K +++ + +E
Sbjct: 10863 QDLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRL--KE 10920
Query: 2867 IMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEEN 3046
+ + +DV +++ +++ L +E+E +N K L++ +++ D + E++
Sbjct: 10921 DLEKMSTDV-NKQNKDLMNQRD----LLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQD 10975
Query: 3047 -------KEHKRQI------AILEKLKEETENNPGRVFLQSEEREKIEEQKRVL-DQALQ 3184
KE ++ + I K K E E ++EE E+ EE+ RV+ + +
Sbjct: 10976 LPKEKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERK 11035
Query: 3185 ECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDS 3364
E ++K++++ S+ID EQ+KLN ++ + +
Sbjct: 11036 ELYQIKSELERVRSEID---HEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSE 11092
Query: 3365 MQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQ 3544
+ +++ N E K++IEK ++ L+ E EE + + QKE + +E+ ++
Sbjct: 11093 LDNKIQQTNLE-KHDIEKSKEIVEKLMVEVEEQRKDIQL------QKEELDIERQKIADE 11145
Query: 3545 KILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKF 3724
+ LL++ +++ + + E+ + + + +E L++ + L+ ++ +L + ET+
Sbjct: 11146 QNLLVQ-NKAKLQNENERIKKVDEEIKKERETLREMEI----HLKKEKEELRSIIEETQR 11200
Query: 3725 LKEKLLVSDENLKEKDLQLR 3784
KE L ++ E+ L L+
Sbjct: 11201 RKEDLEKMSTDINEQKLHLK 11220
Score = 93.2 bits (230), Expect = 8e-16
Identities = 235/1268 (18%), Positives = 500/1268 (39%), Gaps = 170/1268 (13%)
Frame = +2
Query: 527 VSAQEEEFKEAL--AAKDSENFLLNKKI-EDLNHKIWSLEETLQYKEEVILSSHETISER 697
+ + +E K+ K+ EN L K+I ED KI ++ LQ + E +T +R
Sbjct: 2725 IKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAE------DTEKQR 2778
Query: 698 DRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSL 877
+ KD + ++++ + E + S D + + L + KQ ++T
Sbjct: 2779 RDIEKDRRNNEEMVIKLQNEKKDIETSTDR------IRDEEANLEVQKQRLESDRDTLEK 2832
Query: 878 DCF--RRDEIEDQNIKEEIEKQIVE-TIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDE 1048
+ F + + E N+K+++E QI + I + +IQ+ E + L++ +K +++++ +D
Sbjct: 2833 ERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERD- 2891
Query: 1049 CHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNS 1228
C KE +A+IS LS L+E +++ T ++ D++ + R ++ +K
Sbjct: 2892 CFEKE---KADIS-LSEDLKEQSEREGIDNTRTR------IKQEMDELEKTRQNL-AKEQ 2940
Query: 1229 YIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERG 1408
+ L +I + E +K+++ +KA ++ + K K EL+ ER
Sbjct: 2941 ENNELQKKI--IEDERDKIEQ------------------IKAELKKEAEKTKLELQNERQ 2980
Query: 1409 KISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLE 1588
+ E ++ K ++ LAE + + + +
Sbjct: 2981 NLEEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIELKK 3040
Query: 1589 ELTD----QINIFNSVIDKKE------AEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQS 1738
+TD + ++ N +++++E AE+ D + L+ +S Q+ +I + L+
Sbjct: 3041 TVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQLRL 3100
Query: 1739 FESHIEKL---VNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQE 1909
E +E+L + E+++ ++ + Y L + R N + A
Sbjct: 3101 REVELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREV--NQMMEYASKDR 3158
Query: 1910 QHIEHQCKEEL-EGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSL- 2083
++E + E + + H D+ LN I R + ++ E D +R AL E+K L
Sbjct: 3159 ANLEKEKSEMIAQKHQMDIELNKERGLI---EERTQMLNTYEKEMDQKRTALEVEMKELK 3215
Query: 2084 --------------HQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEA---S 2212
+EL + + +K L + + ++ +++ KD A
Sbjct: 3216 YHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLAHLAE 3275
Query: 2213 DVQGKSRALR-RHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAI---LAFETA 2380
D + K ++ H + A + K S K E +E+KK++ L A
Sbjct: 3276 DTKRKDDEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQQMQA 3335
Query: 2381 DASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXX 2560
+ + K+ ++ + + + ++ EL +++E++ + +L EK L +
Sbjct: 3336 EINRQQTEMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLTEKELLESDRK 3395
Query: 2561 XXXXXXXXXVAE---ITGKFEKVLQENKLLP----------------VEEVQRYKM---- 2671
+ I E + Q+ +LL EE+++ K+
Sbjct: 3396 LLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQH 3455
Query: 2672 -----------LCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLS--DALKKSADHAQRE 2812
+ +E LQ D++ +EI + K + +K D LK + Q+E
Sbjct: 3456 ERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQE 3515
Query: 2813 SH-----LLKHIADLEAGITDREIMTSVCSDVLTALFVEMVR------EKEFSLSLATKE 2959
++K ++L+ ++ + + +D++ + E + E E KE
Sbjct: 3516 LEKEKEIIMKDRSELDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKE 3575
Query: 2960 QETVNQ---------KQMSLRKML--EDKDKLLCLVGEENK-EHKRQIAILEKLKEETEN 3103
+ +Q K M L+K + E+K+KL E+ K E +R+ + K+KEE +N
Sbjct: 3576 KHDFDQGRNSLDEDLKMMKLQKQVFEEEKNKL-----EQMKIELEREAGEIRKIKEEIQN 3630
Query: 3104 NPGRVFLQSEE--REK---------IEEQKRVLDQALQECEELKNDIQNKHSDIDSLRE- 3247
+ +EE REK ++++ +LD+ E L ++Q + S+ + +RE
Sbjct: 3631 ERQSLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMREN 3690
Query: 3248 -------------------------------EQEKLNKQLRCMXXXXXXXXXXXXXXXXX 3334
+Q ++ K+ +
Sbjct: 3691 ISKQTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHK 3750
Query: 3335 XXXISSNLDSMQLELRNYNEE------LKNEIEKKSTDIDLL------------------ 3442
+ + +S++L+ + E +K E+E+++ +I+ +
Sbjct: 3751 IISLDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQI 3810
Query: 3443 IKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSL 3622
KE++++N + T + K+ VL EK + E+KI ++S + ++ + L
Sbjct: 3811 TKERDKINNLIEETNR----KDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSEL 3866
Query: 3623 TEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEK--DLQLRAFEI 3796
+ DL+KQ + E+Q + DLE ++ +E +K+K +L EI
Sbjct: 3867 YKVKEDLEKQKENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEI 3926
Query: 3797 ANSEKQYQ 3820
N +++ +
Sbjct: 3927 QNLQQELE 3934
Score = 91.7 bits (226), Expect = 2e-15
Identities = 261/1407 (18%), Positives = 533/1407 (37%), Gaps = 232/1407 (16%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAET-LERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRN 448
+EVE+ RK ++ + E +ER +I D N L L +N + + E+I+
Sbjct: 11119 VEVEE----QRKDIQLQKEELDIERQKI--ADEQNLLVQNKAKLQNENERIKKVDEEIKK 11172
Query: 449 TKDLLDTVESGLYVSNVVSDAVLNGVVSAQEE------EFKEALAAKDSENFLLNKKIED 610
++ L +E L +++ +E+ + E ++ LL ++ E+
Sbjct: 11173 ERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREE 11232
Query: 611 LNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNE 790
+NH++ L++ + + + E +++++ + K L + +A+ E K + E
Sbjct: 11233 INHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEE----RKSLEETKARIIEMKTKAELQE 11288
Query: 791 MMHMVLEKDNIILSLHKQIELQSQNTQSLDCFR-RDEIEDQNIKEEIEKQIVE------- 946
+M E+D + + ++E + N + R R EI+ + K +K+I+E
Sbjct: 11289 IMQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLE 11348
Query: 947 ---TIYVTQIQELGEE---------------HDL--------------------LRLESA 1012
+ +TQ Q++ EE HD+ +RL+
Sbjct: 11349 KMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKE 11408
Query: 1013 KYQDEIQSLKDEC---------------HAKEMSKQAEISKLSHTLEESIMNSNLESLFT 1147
+ E Q + DE KEM + EI K TL+E + E
Sbjct: 11409 ELDIERQKIADEQGLVVQNKAKLQNENERIKEMDE--EIKKEKETLKEMEAHLRKEKEEM 11466
Query: 1148 AEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXX 1327
+ E T R + + ++ D+ +N L ++ D L E ++ +
Sbjct: 11467 RSVIEETQRRKKEDLEKMSTDVNKQNQ---DLMNQRDLLKQEREEINHKWTQLQQRID-- 11521
Query: 1328 XXXXXTLKASMEMQCSKLKDE-------LEEERGKISENLERISKLQKMNNE---LAERS 1477
+ Q SK K+E +EEER + E +I +++ E+
Sbjct: 11522 ---------EFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKE 11572
Query: 1478 KSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSV---IDKKEAEV 1648
K + + V + ++L D + ++K ++E+
Sbjct: 11573 KEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEI 11632
Query: 1649 SGHLDTISSLQTVLSN-------QKFEIEKSQKVLQSFESHIEKLVND---SLHEVD--- 1789
+ ++ L N ++ +IE S++++Q +E+ D E+D
Sbjct: 11633 MKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIER 11692
Query: 1790 --------------SAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQE--QHIE 1921
+ + N R + ++ ETL+ +++ + + + +
Sbjct: 11693 QKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQ 11752
Query: 1922 HQCKEELEGHIADLVLNDFSNDILSWS---RRKEEAVVHD--------DEFDAERIALLN 2068
+ KE+LE D+ N + D+++ +++ E + H DEFDA+
Sbjct: 11753 RRQKEDLEKMSTDV--NKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQ------ 11804
Query: 2069 ELKSLHQDL-ELLKAEEAVKSLSNN-VGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALR 2242
K +DL + K EE KSL + + + I++ K+ E +V ++
Sbjct: 11805 VSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMK 11864
Query: 2243 RHSTGQA------------FREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADA 2386
+ Q + +D E + +E +E K + E ++
Sbjct: 11865 KEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSEL 11924
Query: 2387 SDSPLRNWPKEQLLGHFKQSFAGL-----KREYELELQRKT-----EEIYDLKRLLLNEK 2536
+ + + ++ + + K+ L ++++E++ Q++ ++I D + LL+ K
Sbjct: 11925 ENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNK 11984
Query: 2537 NGLH------AXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKM--------L 2674
+ L + E+ EK +E K + EE +R K +
Sbjct: 11985 SELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSI-TEETRRQKEDLEKMSTHI 12043
Query: 2675 CVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGI 2854
K++L+S+ D L +E +E + K L +++ + + + Q+E L K E
Sbjct: 12044 NEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSK--QKEEDLPKEKEMKEDRK 12101
Query: 2855 TDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLV 3034
+ E ++ A E+ +EKE +EQE + +M +++ + K +L +
Sbjct: 12102 SLEETKANILEMKTKAEPEEIKKEKEKE----EEEQEMRVKVEMERKEIEQIKSQLERVR 12157
Query: 3035 GEENKEHKR---QIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKN 3205
E + E K+ ++E+ KE+ E + Q R+++EE++ LD+ +++ + K+
Sbjct: 12158 SEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQ---RQQMEEERSELDKKIKQTDLEKH 12214
Query: 3206 DIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXIS------------ 3349
DI+N ++ L E EK +++
Sbjct: 12215 DIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQQNENERIKE 12274
Query: 3350 ---------SNLDSMQLELRNYNEEL----------KNEIEKKSTDI-----------DL 3439
L M++ L+ EE+ K ++EK STDI DL
Sbjct: 12275 MDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDL 12334
Query: 3440 LIKEKEELNERLAYTQKAMEQKEAV----------------------------LVEKLFE 3535
L +E+EE+N +L Q+ +++ E ++E+
Sbjct: 12335 LKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNR 12394
Query: 3536 GEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTE 3715
++ +E QS + E +DLL +E D +K+ EELQ + DLE+ M E
Sbjct: 12395 KRTELEEIEVDQSQQNKNVETMKDLLE---KERKDTEKE----REELQKQADDLEMQMIE 12447
Query: 3716 TKFLKEKLLVSDENLKEKDLQLRAFEI 3796
KE++ + ++K L+ +A EI
Sbjct: 12448 HGD-KEEMSKRSLDEEKKLLEQKANEI 12473
Score = 90.5 bits (223), Expect = 5e-15
Identities = 236/1241 (19%), Positives = 467/1241 (37%), Gaps = 149/1241 (12%)
Frame = +2
Query: 539 EEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISER-DRLLKD 715
+ E ++ + +LN + ++LN +LE+ KEE L S R + LL+D
Sbjct: 12998 QAELQKGQLEMEMHQLMLNSERDELNGMRVNLEKQ---KEEFELMQQNLESRRPESLLED 13054
Query: 716 FIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQ----SLDC 883
+ EK +++ A + ++ N M + + I KQIE + + Q L+
Sbjct: 13055 ILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKI-----KQIEGEIKTKQIEMACLEE 13109
Query: 884 FRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSL-----KDE 1048
++ E+++Q E E Q ++Q EE ++ E +DEIQ L K++
Sbjct: 13110 LKQKELDEQKNMRECENQ--------ELQMRREELAKMKTEIDIERDEIQKLRKQYEKEK 13161
Query: 1049 CHAKEMS---KQAEISKLSHTLEESIMNSNLESL---------FTAEIYENTFRE---LG 1183
C +++ ++ E K+ ++ ++ ++SL A++ +N RE +
Sbjct: 13162 CELEQIKPDLQKREPEKIDAEVQHDEIHGGIDSLKEEREEIEKMKADL-QNKLREAENMR 13220
Query: 1184 DQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTL----- 1348
D + + ++++ K + I+ +A + S+ N LQ++ L
Sbjct: 13221 DIMKREKDELEKKEAEIEQMAVETEDNDSDKN-LQDEMMKIEAILKVTKKQKNYLEQMNE 13279
Query: 1349 -----KASMEMQCSKLKDELEEERGKISENLE-RISKLQKMNNELAERSKSQNSIXXXXX 1510
K +E C L+ E E K+ E E +SK++ ER + +I
Sbjct: 13280 NLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKME-------EREAERKTIERVMD 13332
Query: 1511 XXXXXXXXXXXXXXXVVNMAFGSK-----LEELTDQINIFNSVIDKKEAEVSGHLDTISS 1675
+VNM K LEE +++ S + + +E+ +
Sbjct: 13333 EMAEEHEKIKKEREELVNMEEEIKKQRRVLEESMNEMTKKKSELQHERSELYKQKQQLED 13392
Query: 1676 LQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGE 1855
+ + S K +++ + + I K + + ++ + +++ E
Sbjct: 13393 M--IASESKRDVDTERSRQDKEDEQILKREREEIADMKDQLLKEKEDVETTKERINREKE 13450
Query: 1856 TLRAFVKNIQNQVAVSQEQHIEHQ----CKEELEGHIADLVLNDFSNDILSWSRRKEEAV 2023
+ + +Q +E +E+Q K E++ + L D L R A+
Sbjct: 13451 HIEKMQSQLNDQ---KEEMDLENQKLLYMKTEIQ--VKTNALEKMMQD-LQKERENVNAL 13504
Query: 2024 VHDDEFDAERIALL---NELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEG 2194
V + + E+ +L N+ K H + E+ + E ++S+ + + I + ++
Sbjct: 13505 VIQHQKEREQRDILIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTR 13564
Query: 2195 KDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFE 2374
+ E ++ K + + RE E + E K E EK + +
Sbjct: 13565 SE-ELENLIKKQQKEFETKENEMQRERKALEKMNAEL-ERKSTELKNKIEKVTVWEADLQ 13622
Query: 2375 TADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKT-----EEIYDLKRLLLNEKN 2539
L+N + + +++ ++++E+E RKT E + L+ L +EK
Sbjct: 13623 KEKNKTEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKK 13682
Query: 2540 GLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLL 2719
+ + EI + E + +E K L + + L ++ L
Sbjct: 13683 SMLSRLSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKL 13742
Query: 2720 KEIKEKDSNSKVLA------EKLSDALKKSA--------------DHAQRESHLLKHIAD 2839
+EKDS ++ A EKL + ++K+ D ++E L AD
Sbjct: 13743 SIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRAD 13802
Query: 2840 LEAGI-----------TDREIMTSVCSD---------------------------VLTAL 2905
+E T++EI+ ++ L +
Sbjct: 13803 IERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEKQRKRNDLTLQELRKEKMALEQM 13862
Query: 2906 FVEMVREKEFSLSLATK---EQETVNQKQMSLRKMLEDKDKL-LCLVGEENKEHKRQ--- 3064
++ +EK+ SL + +Q + K+ L + ++ D L + L +N +K+Q
Sbjct: 13863 ITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEV 13922
Query: 3065 -IAILEKLKEETENNPGRVFLQSEERE------KIEEQKRVLD-------QALQECEELK 3202
+ I+E +K + + L E R+ E+QK VL Q E E+
Sbjct: 13923 DVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFT 13982
Query: 3203 NDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELR 3382
DI+ + ++ REE + LNK++ L S+ LE+
Sbjct: 13983 TDIKTEKEHVEKEREEIDVLNKEI---------------------IKSKEELQSLNLEI- 14020
Query: 3383 NYNEELKNEIEKKSTDIDLLIKEKEEL------NERLAYTQKAM------EQKEAVLVEK 3526
E K EI K I+ L + + +L + L T+K M ++ E L
Sbjct: 14021 ---EMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMN 14077
Query: 3527 LFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVA 3706
L + + ++ L ++ A + Q E + +L+ +E D+ S + L+ ++ +L
Sbjct: 14078 LQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKL 14137
Query: 3707 MTETKFLKEKLLVSDENL-----KEKDLQLRAFEIANSEKQ 3814
+ L EK+ E L KE+D +I SEKQ
Sbjct: 14138 ---SHVLNEKVQREQEELERLLEKERDDIENCKKIIESEKQ 14175
Score = 87.8 bits (216), Expect = 3e-14
Identities = 268/1329 (20%), Positives = 516/1329 (38%), Gaps = 159/1329 (11%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNT 451
+EVE+ D R E +ER +I D + L +N + + E+I+
Sbjct: 11672 VEVEEQRKDIRLQKEEL---DIERQKI--ADEQGLVVQNKAKLQNENERIKEMDEEIKKE 11726
Query: 452 KDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENF-------LLNKKIED 610
K+ L +E+ L +V+ Q+E+ ++ + +N LL ++ E+
Sbjct: 11727 KETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREE 11786
Query: 611 LNHKIWSLEETL--------QYKEEVILSSHETISERDRLLKDFI--------------- 721
+NHK L++ + + KEE + + ER L + I
Sbjct: 11787 INHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIK 11846
Query: 722 -----HEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCF 886
E+++M+ + + +++L +++ + E D+ L+ ++ Q + L+
Sbjct: 11847 KEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKM 11906
Query: 887 R-------------RDEIED------------QNIKEEIEKQIVETIYVT-QIQELGEEH 988
+ R E+E+ +N KE ++K +VE +IQ EE
Sbjct: 11907 KSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEEL 11966
Query: 989 DLLRLESAKYQDEIQSLKDEC-HAKEMSKQAE--ISKLSHTLEESIMNSNLESLFTAEIY 1159
D+ R + A QD + K E + E K I K TL+E E I
Sbjct: 11967 DIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSIT 12026
Query: 1160 ENTFRELGD------QISQLRNDMYSKNSYIDS-----------LASRIDFLSSECNKLQ 1288
E T R+ D I++ + D+ S+ ++ L RID ++ +K +
Sbjct: 12027 EETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQK 12086
Query: 1289 EQXXXXXXXXXXXXXXXXTLKAS-MEMQCSKLKDELEEERGKISENLERISKLQKMNNEL 1465
E+ KA+ +EM+ +E+++E+ K E E K++ E+
Sbjct: 12087 EEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEI 12146
Query: 1466 AERSKSQ-----NSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVID 1630
E+ KSQ + + + M S++ + Q+ S +D
Sbjct: 12147 -EQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMK--SEIMKQRQQMEEERSELD 12203
Query: 1631 KK-------EAEVSGHLDTISSLQTVLSNQKFEIEKSQKVL----QSFESHIEKLVNDSL 1777
KK + ++ + + L + QK EI+ ++ L Q + L+ + +
Sbjct: 12204 KKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKI 12263
Query: 1778 HEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIA 1957
+ + N R + ++ ETL+ N+Q + KEE+E I
Sbjct: 12264 EQQNE-----NERIKEMDEEIKKERETLKEMEVNLQKE-------------KEEIESVIE 12305
Query: 1958 DLV-----LNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAV 2122
+ L S DI + +K++ + D ER + ++L L Q ++ +
Sbjct: 12306 ETQRRKEDLEKMSTDI---NEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFET---- 12358
Query: 2123 KSLSNNVGVSTK---GIHYFSQLIQEGKDGEA--SDVQGKSRALRRHSTGQAFREPPKPE 2287
++N+ V+TK +L Q K+ E+ + K L Q+ +
Sbjct: 12359 ---TSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTELEEIEVDQSQQNKNVET 12415
Query: 2288 DLYTTYSEGKIVEPHPTEEKKL---LAILAFETADASDSPLRNWPKEQLLGHFKQSFA-- 2452
E K E E +K L + E D + R+ +E+ L K +
Sbjct: 12416 MKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILR 12475
Query: 2453 ---GLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVL 2623
L++E E ++ +K E+ L++ + N+KN + + E +K L
Sbjct: 12476 QRDDLEKEKE-DMMKKWNELDGLQKEIQNQKNEMEEIKCELETKRIEIIKE-----QKRL 12529
Query: 2624 QENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIK-EKDSNSKVLAEKLSDALKKSADH 2800
+E+ EE Q +++ V E+ Q +I+ + + K E+D +++A+ L D
Sbjct: 12530 EESLNTVNEERQYLEIVRVDYEKHQQQIEEMRVKTKMERDELDQLMAKMLMD-------- 12581
Query: 2801 AQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQK 2980
++E+ K D++ L EM + K F+L +E + QK
Sbjct: 12582 -RKENERSK--------------------DMIGLLKKEMEQTK-FNLDAQEEELKLEKQK 12619
Query: 2981 QMSLRKMLEDKDKLLCLVGEENKEHKRQ-----IAILEKLKEETENNPGRVFLQSE---- 3133
+ +K LE + E K K Q E LKEE + PG+ F+Q +
Sbjct: 12620 IQNEKKDLEMFKAEIKREASEVKTLKEQQLEKDTKAFEALKEE--HLPGQ-FVQQKGGEF 12676
Query: 3134 EREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSL-----REEQEKLNKQLRCMXXXXX 3298
ER +I+E KR+L + +E +EL+ + Q ++L ++ E+L+ L
Sbjct: 12677 ERIQIDEVKRILSEIHKEKKELERNKQILEHQREALLEIKSKQPSERLDVILVSSATQTS 12736
Query: 3299 XXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLA 3478
+ + D ++ + +E + EI+K D +K E + ++A
Sbjct: 12737 DLEDIPDVSASQGETVEKHTDIIKEYTTSIPKE-EYEIDKLKQQGDKKLKSTRE-DTKMA 12794
Query: 3479 YTQKAMEQK---EAVLVEKLFEGE--------------QKILLLESSQSATREQTEKYRD 3607
T+ + K + ++ KL G+ +++ + + + + +++ EK R
Sbjct: 12795 DTEVTTQYKYIPDPSIMMKLESGKDETDGLTEVHTTERRELEITKLALQSEQQEIEKIRQ 12854
Query: 3608 LL----NSLTEEHADLKKQF-------LSATEELQSKERDLEVAMTETKFLKEKLLVSDE 3754
+ N L + +DL+KQ+ + E E DLE + ETK +E+L +
Sbjct: 12855 DIDREKNDLEKYRSDLEKQYEEMEICKQNIENERAELEIDLENIIIETKSKQERLESIEV 12914
Query: 3755 NLKEKDLQL 3781
L+EK++Q+
Sbjct: 12915 QLQEKNVQM 12923
Score = 84.0 bits (206), Expect = 5e-13
Identities = 228/1214 (18%), Positives = 473/1214 (38%), Gaps = 129/1214 (10%)
Frame = +2
Query: 527 VSAQEEEFKEALAAKDSENFLLNKKIEDLNHK---IWSLEETLQYKE---------EVIL 670
+ ++E+ ++ L A +EN LN++ + L+ K + S + L+YK+ +V
Sbjct: 1340 LQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSEKSKLEYKKPLEIKQVDAQVQT 1399
Query: 671 SSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASR----DNEMMHMVLEKDNIIL--- 829
E SE D L I E D +Q + +Q+L ++ + +M + L +D + L
Sbjct: 1400 ELMEDASEYDMALS--IEELDKQRQFLEYFKQELLAQKCTMERQMAEIELSRDELSLREA 1457
Query: 830 ----------SLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELG 979
+ Q+ELQ Q + +DE+E K E++K V+ TQI E
Sbjct: 1458 TLQTATQTTADMELQLELQKQELEQT----KDEME--RTKLEVQKGWVDL--QTQIAESR 1509
Query: 980 EEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAE-- 1153
E+ +++R+E K +D + ++ + ++ + +A+ L TL + N + +
Sbjct: 1510 EKEEMVRIELEKARDVLNRIRQDVETEKQTMEAD---LKFTLAKEFENLEAQRKMMEDEK 1566
Query: 1154 -IYENTFRELGDQ---ISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXX 1321
EN EL + I + +++M+ + +++ A ++ E K +
Sbjct: 1567 RALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERS 1626
Query: 1322 XXXXXXXTLKASMEMQCSKLK-----------------DELEEERGKISENLERISKLQK 1450
L+ E+ +++K DE+E E+ KI + ++Q
Sbjct: 1627 REIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQT 1686
Query: 1451 -MNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMA-----------------FG 1576
+N + E QN++ V +M
Sbjct: 1687 DLNRQQKEMQDIQNAVFMEKSELKKSQDEIAEQLKQVGDMMQFTQNEKDNLDRERAAIIE 1746
Query: 1577 SKLEELTDQINIFNSVID-----KKEA------------EVSGHLDTISSLQTVLSNQKF 1705
KL+ D ++ N ++ KKE + + + ++ L +K
Sbjct: 1747 QKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKE 1806
Query: 1706 EIE-----------KSQKVLQSFESHIEKLVNDSLHE---VDSAFCSL---NSRFYSLIH 1834
E++ K + VLQ+ EKL D+L E ++ A L ++
Sbjct: 1807 EMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAE 1866
Query: 1835 KVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSN--DILSWSRR 2008
+ E + I+ Q ++ + Q + + + V D N D+ ++
Sbjct: 1867 ETKRKREDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQK 1926
Query: 2009 KEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQ--- 2179
+ + + E +R L+E++ + D E + E L + FS+
Sbjct: 1927 ERQYMDRLVEEIEKRTKALDEMQ-MEVDKERQEVESKRDELEQETSKLREDEDEFSRQKE 1985
Query: 2180 ---LIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKK 2350
+IQ E+ +++ +S + + T F + L +E K + + K
Sbjct: 1986 KNNIIQAEIQKESDNLELQSENISKERT--IFELEKEHLGLRENEAEYKQKQIDELQNKL 2043
Query: 2351 LLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLN 2530
+ + E A R + +++ A ++ E+E R+ E + ++ +N
Sbjct: 2044 RMEKVQVEQMQADKDQQRKKAEYVKTARGRETTALEEQRQEMESLREEYENVEKQKKHVN 2103
Query: 2531 EKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYK-MLCVLKEELQSKI 2707
E+ L + + + EN E +++YK L E+LQ +
Sbjct: 2104 EQKEL-----------------FESRMKSLEMEN-----EAMKKYKEKLDKEYEDLQFQR 2141
Query: 2708 DSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDR-------E 2866
KEI++ + ++ AE + + KK + + + ++ + + + ++ E
Sbjct: 2142 QLFEKEIQQMRTELQIEAENI-ERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDE 2200
Query: 2867 IMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLC--LVGE 3040
+ + +D+ VE + ++L ++E+ +K+ K+ E++ + L +
Sbjct: 2201 VRKKINADLSE---VEKQKSALVQMNLKISQEESYVKKEKDRLKLQENEQNMQMSQLNAK 2257
Query: 3041 ENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNK 3220
+N+ +RQ A +EK K E EN R+ E+EK+E + + Q E++N+++ K
Sbjct: 2258 QNELDERQ-AEMEKQKRELENVMDRL-----EKEKVE-----ITKEKQRVNEMQNEVKRK 2306
Query: 3221 HSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEE- 3397
++ +D ++ QE L +Q I ++ + + EL E+
Sbjct: 2307 NASVDLIK--QEVLREQ----------------------DHIENSREILNRELEKIKEKK 2342
Query: 3398 --LKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAV---LVEKLFEGEQKILLLE 3562
L E E +++ KE + L + A QK E E + E+ ++ L+
Sbjct: 2343 TILAEEFEALDDKKEMIGKEMQRLGKMKAELQKEAEDTEKQRRDIDNDRRNNEEMVIKLQ 2402
Query: 3563 SSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKER-DLEVAMTETKFLKEKL 3739
+ + T++ RD E + ++KQ L + + KER DLE TE K L+++L
Sbjct: 2403 NEKKDIETSTDRIRD-----EEANLRVQKQRLESDRDTLEKERFDLEKTKTEMKDLEKQL 2457
Query: 3740 LVSDENLKEKDLQL 3781
+ ++ ++QL
Sbjct: 2458 ---ESQSRQHEIQL 2468
Score = 83.2 bits (204), Expect = 8e-13
Identities = 212/1227 (17%), Positives = 466/1227 (37%), Gaps = 63/1227 (5%)
Frame = +2
Query: 320 KIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGLYVSNV 499
+I L+ + DT N + +L +D + ++++ +++ + + L +
Sbjct: 7559 QIRAELQNKQRDMDDTTNIMMKEKAELARDLENLQNEKDELQKSRENIQKLMKELQEERL 7618
Query: 500 VSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSH 679
+ LN + ++F E + K N ++++ +I + L +E+I
Sbjct: 7619 KTSEALN----KERQQFTEEIKLK-------NDSLDEIQAEIDRQKRALVTDKEIITKQM 7667
Query: 680 ETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMV--LEKD-NIILSLHKQIE 850
+ + + + E D+ + Q + L E++ LE++ + +L + +E
Sbjct: 7668 MDLQKTQDVRRQS-DESDIARANLQRERESLDQLSVEILKQKQDLERERDELLEQWRLVE 7726
Query: 851 LQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEI 1030
Q + +++ + + ++++ E+I KQ+ + + +L +L L K
Sbjct: 7727 TQKMDNENVKQLKTELLDEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNLQK----- 7781
Query: 1031 QSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRND 1210
Q ++DE +A++ ++ L+ + ++E +YE + ++ +++
Sbjct: 7782 QGIQDE--------RAQLERMKGELQ--MKADDIERKMQEILYEK------QKYAERKSE 7825
Query: 1211 MYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDE 1390
Y +Y+D + + L+ E + E K +E+ ++ + E
Sbjct: 7826 NYKIQTYLDEANAEVQKLNKELERYDENLE----------------KCKLELDKARAETE 7869
Query: 1391 LEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMA 1570
++ KI E + LQK + +
Sbjct: 7870 RVKQGAKIPETQQIEQSLQKERDYI----------------------------------- 7894
Query: 1571 FGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESH 1750
E++ + I+K +AE+ + +Q + QK E+ K QK+ E
Sbjct: 7895 -----EDIRRNLFKKEEAIEKDKAEIRLRHQELDLIQAKVVKQKEEMVK-QKIESEREIQ 7948
Query: 1751 IEKL-VNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQ 1927
EK + S E++ + L D + + R V N QVA +
Sbjct: 7949 QEKKKLQRSEEELEDKMQKIKREMIELKLLQDET-DGKRKDVDNKMRQVA---------R 7998
Query: 1928 CKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLK 2107
++ELE AD+ + S + +++ + + ERI ++ + H
Sbjct: 7999 KRDELEKMKADV-------ESASKKLEVDRVMLNTERDELERIKTESQRATEHMQSH--- 8048
Query: 2108 AEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPE 2287
AEE L V+T+ +LIQE + K R + E
Sbjct: 8049 AEERAGDLGEKEPVNTR----IQRLIQEAEKASKMAWSTKHEPEMRMQREVSVEEESVER 8104
Query: 2288 DLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKRE 2467
+ + I+E E + A S L N E L K++ +
Sbjct: 8105 QDMSANMQRMILEIEHARETLRGMKDEVQAARKERSELENMKLEFLT--MKKNMEKTYEQ 8162
Query: 2468 YELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPV 2647
E+Q++ ++I K LL E+N L + +K+L EN+LL
Sbjct: 8163 QNDEIQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMALDK----QKLLAENELLER 8218
Query: 2648 EEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLK 2827
E+ K++ E L+S + +E A + + A ++ ++ ++ L
Sbjct: 8219 EKADVIKII----ENLESLREEATRE----------RATETAQATRRDSEELMQKMEALS 8264
Query: 2828 HIADLEAGITDREIMTSVCSDVLTALFVEMVREK-EFSLSLATKEQETVNQKQMSLRKML 3004
+ D + ++ + D L L ++++++ E + A +Q+ + ++ +
Sbjct: 8265 -MEDFQEASKNQMVELKRQIDKLIELKADLLQQQTELKKTKADLKQQMDDLEKTRSEILK 8323
Query: 3005 EDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEE----REKIEEQKRVLD 3172
+KD ++K + ++ +++ K++ E ++ L+ + R +I +K+ LD
Sbjct: 8324 HEKDT-------DSKTRELELIEIQRQKDDLETRIQKLTLEKRDLEVLRSEIVLEKKDLD 8376
Query: 3173 QALQ-------ECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXX 3331
Q ++ E E++++DI N +I+ R+E E L ++
Sbjct: 8377 QKMKQVIRKRDEMEKIRSDIANATEEINRERQELEILRNNVQ-SARHDFELLLERTANLE 8435
Query: 3332 XXXXISSNLDSMQLE-------LRNYNEELKNEIEKKSTDIDLLIKEKEELN-------- 3466
+++++ + LE +RN E++ +EK +ID K E+
Sbjct: 8436 DEESAATDIERLVLEVVKIREMVRNLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDIGQ 8495
Query: 3467 ------------ERLAYTQKAMEQKEAVLVEKLFEGE----------QKILLLESSQSAT 3580
E+ ++ +E+ A L EK E E +++ L+ +
Sbjct: 8496 IRENLGGLGEEIEKTRRDKRELEKMRAELAEKQQEQESMREMLHKEREELEQLKDEINRE 8555
Query: 3581 REQTEKYRDLLNSLTE-----EHADL---KKQFLSATEELQSKERDLEVAMTETKFLKEK 3736
+E E R+L+ ++ + E D+ K++ S TEEL +K+RDL+ ++ + L++
Sbjct: 8556 KEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQT 8615
Query: 3737 L--LVSDENLKEKDLQLRAFEIANSEK 3811
+ + K +L+ FE+ E+
Sbjct: 8616 IEEINIQHGKKRAELEGIGFELKKGEQ 8642
Score = 81.6 bits (200), Expect = 2e-12
Identities = 236/1220 (19%), Positives = 470/1220 (38%), Gaps = 75/1220 (6%)
Frame = +2
Query: 266 SFIEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIR 445
S I+V+ ++ + K + +E+M+ D N L+ D+ + + D++
Sbjct: 279 SAIQVQINEIEMKIGETQKAKDLMEQMKAEIEDEKNELEKKKEDIKRQRDQFEQIKLDLQ 338
Query: 446 NTKDLLD-----TVESGLY------------------VSNVVSDAVLNGVVSAQEEEFKE 556
K ++ T + GL + V + N S QE
Sbjct: 339 QVKMEMEQRWHETEKEGLEQRAVIQREKEQLKYLQDEIQRVREEVERNREFSKQEHARIS 398
Query: 557 ALAAKD-SENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEKD 733
L A+ EN L+ K D+ K LEE K E+ ER R ++ + +
Sbjct: 399 QLRAQALEENNLIENKWHDILRKEKDLEEM---KHEI---------ERGR--EELVMNGE 444
Query: 734 LMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQN 913
L+++ ++ EQ + M+ M D I + ++++ + D + + + +
Sbjct: 445 LVKKEWEKIEQAKVDIQSHMISMEGRVDEIKRETERLKHIKTEMQRDKDALEKQKDDTRK 504
Query: 914 IKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKL 1093
KEE E++ E VT+ E R E + E+Q + D AK + ++ E ++
Sbjct: 505 AKEEAERKRYEI--VTEELEHRARLQRERDELENIRAEMQRVNDVEKAKILKEKEESIRI 562
Query: 1094 SHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSE 1273
EE+ L AEI R Q LR + ++L ++ + +S+
Sbjct: 563 R---EEARQERETTELVNAEIKAEKERLNQRQEEMLRERQEIERIKHETLRAKEEIENSQ 619
Query: 1274 CNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSK-----LKDELEEERGKISENLERIS 1438
++E K E+Q +K K ELEEER E+LER
Sbjct: 620 DVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKEQMEEAKVELEEER----EDLER-- 673
Query: 1439 KLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEEL-TDQINIF 1615
K ++ E+ + +N I V S+ E T+++ +
Sbjct: 674 KRDLVSREIEQAEFLRNEILR-------------------VKEEMESRWRETETEEVEL- 713
Query: 1616 NSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSA 1795
A+ L+ + L+ + IE+S+ L ++ ++KL + +
Sbjct: 714 -------RAKTQHELERLEKLREETERSQKNIEESKIELMLWKESLDKLKGEMEEDKHVV 766
Query: 1796 FCSLNSRFYSLIHKVDNSGETLRAFVKNIQ---NQVAVSQEQHIE-----HQCKEELEGH 1951
+N + E L ++ ++ ++ +S+E+ E ++ + EL+
Sbjct: 767 IMQMN--------EAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQ 818
Query: 1952 IADLVLNDFSNDILSWSRRKEEA-----VVHDDEFDAERIALLNELKSLHQDLELLKAEE 2116
A++ D+ + ++ KEEA VH+ E ++ +E + E L+ +
Sbjct: 819 HAEM--EDWFRVV---NKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRD 873
Query: 2117 AVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLY 2296
++ + + K I Q +++ + E +Q + L + F E + E L
Sbjct: 874 EIQKKAEELEQINKEIQRARQELEKMRYFEKESLQ---KMLEDTQQERVFVEQVRSELLK 930
Query: 2297 TTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYEL 2476
+ K + +E K+L + + D R + E + +QS
Sbjct: 931 NKADQDKCLFEMDSERKELEQMRFQVENEKKDLEQRRY--EMMRYDVEQS---------A 979
Query: 2477 ELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEV 2656
++QR+ EE+ +K L+ + ++ I E+ NK L E
Sbjct: 980 QVQRQKEELEKIKSQLVIDTESMNRSRELARQDREKAELLIVEIQEQREDVNKRLE-ETK 1038
Query: 2657 QRYKMLCVLKEELQSKIDSLLK-------------EIKEKDSNSKVLAEKLSDALKKSAD 2797
QR + L +L+++++++ + L K E+KE+ + + E+L D +K D
Sbjct: 1039 QREEALRLLRKDMENEREDLEKIRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKG-D 1097
Query: 2798 HAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKE-FSLSLATKEQETVN 2974
+RE + H + E I E M ++ + VE+ ++KE + + E N
Sbjct: 1098 QEEREK--INH--EKEEMIRKMEAMKREMGEI-EDMKVELTKQKENIDMKMEHARLEMTN 1152
Query: 2975 QKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEE 3154
+ M + + +D ++ +++ + ++ E LK++ + L+ E I+E
Sbjct: 1153 LEMMKADLLRQKEDIENQMLAAKSERQQMEVMRTEILKQKED-------LEERLEEVIKE 1205
Query: 3155 QKRVLDQALQECEELKNDIQNKHSDIDSLREE---------QEKLNKQL---RCMXXXXX 3298
RV E+++ D+ N DID +E+ QEK+ + +
Sbjct: 1206 NDRV--------EQMREDVNNALKDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKT 1257
Query: 3299 XXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELN---E 3469
+S+++ + EL +Y E +++KEK ELN E
Sbjct: 1258 EEPGAIKSYRASDLELSASIQKERQELEHYKE--------------IILKEKHELNKIKE 1303
Query: 3470 RLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADL-- 3643
+ + E++ L E+ E + K + L++ + + + EK + L+++ E+ L
Sbjct: 1304 DVKAVKNDAEERMIKLHEEEKEMKTKRVSLQNWERQLQTEKEKNQKGLDAIWNENQQLNE 1363
Query: 3644 KKQFLSATE-ELQSKERDLE 3700
+KQ L E LQS++ LE
Sbjct: 1364 RKQQLDIKELHLQSEKSKLE 1383
Score = 80.1 bits (196), Expect = 7e-12
Identities = 188/1084 (17%), Positives = 437/1084 (40%), Gaps = 60/1084 (5%)
Frame = +2
Query: 722 HEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSL-HKQIELQSQNTQSLDCFR-RD 895
HEK+ M ++ + ++++ ++ + + +K+NI + + H ++E+ + D R ++
Sbjct: 1106 HEKEEMIRKMEAMKREMGEIEDMKVELTKQKENIDMKMEHARLEMTNLEMMKADLLRQKE 1165
Query: 896 EIEDQNIKEEIEKQIVETIYVT----------QIQELGEEHDLLRLESAKYQDEIQSLKD 1045
+IE+Q + + E+Q +E + +++E+ +E+D R+E + +D +LKD
Sbjct: 1166 DIENQMLAAKSERQQMEVMRTEILKQKEDLEERLEEVIKEND--RVEQMR-EDVNNALKD 1222
Query: 1046 ECHAKE-MSKQAEISKLSHTLEESIMNSNLESLFTAE-----IYENTFRELGDQISQLRN 1207
AKE + +Q E+ + + E T E Y + EL I + R
Sbjct: 1223 IDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAIKSYRASDLELSASIQKERQ 1282
Query: 1208 DMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKD 1387
++ I ++ + + ++ T + S++ +L+
Sbjct: 1283 ELEHYKEIILKEKHELNKIKEDVKAVKNDAEERMIKLHEEEKEMKTKRVSLQNWERQLQT 1342
Query: 1388 ELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNM 1567
E E+ N + + + N +L ER + + V+
Sbjct: 1343 EKEK-------NQKGLDAIWNENQQLNERKQQLDIKELHLQSEKSKLEYKKPLEIKQVDA 1395
Query: 1568 AFGSKLEELTDQINIFNSV--IDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSF 1741
++L E + ++ S+ +DK+ + + + + + Q EIE S+ L
Sbjct: 1396 QVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCTMERQMAEIELSRDELSLR 1455
Query: 1742 ESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVK---NIQNQVAVSQEQ 1912
E+ ++ + L + L D T K ++Q Q+A S+E+
Sbjct: 1456 EATLQTATQTTA----DMELQLELQKQELEQTKDEMERTKLEVQKGWVDLQTQIAESREK 1511
Query: 1913 HIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHD-----DEFDAERIALLNELK 2077
E + ELE A VLN D+ + + E + + +A+R + +E +
Sbjct: 1512 --EEMVRIELEK--ARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQRKMMEDEKR 1567
Query: 2078 SL-HQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQ---EGKDGEASDVQG----KSR 2233
+L + EL + ++ +N+ + + +++ ++ E + + D+Q +SR
Sbjct: 1568 ALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERSR 1627
Query: 2234 ALR-----RHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSP 2398
++ R + D+ SE + E +K + +
Sbjct: 1628 EIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQTD 1687
Query: 2399 LRNWPKEQ--LLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXX 2572
L KE + + LK+ + E+ + +++ D+ + NEK+ L
Sbjct: 1688 LNRQQKEMQDIQNAVFMEKSELKKSQD-EIAEQLKQVGDMMQFTQNEKDNLDRERAAIIE 1746
Query: 2573 XXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSK 2752
++T + L+ KL+ E + ++L E+ + SL++++++ + K
Sbjct: 1747 QKLQMERDMTHLLNRELESLKLVKKEVLNEKRLL----EDCRI---SLMRDMQDLEQ-MK 1798
Query: 2753 VLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDR-EIMTSVCSDVLTALFVEMVREK 2929
+ E+ + ++ E L+ + A T++ I T L VE+ +E+
Sbjct: 1799 INLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKER 1858
Query: 2930 EFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNP 3109
+ +++A E +K+ + K+ +K + + +++ AI+E ++ + +
Sbjct: 1859 DEIMNIA----EETKRKREDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQAVQKDI 1914
Query: 3110 GRVFLQSEEREKIEEQKRVLDQALQECE-------ELKNDIQNKHSDIDSLREEQEKLNK 3268
V + +I+++++ +D+ ++E E E++ ++ + +++S R+E E+
Sbjct: 1915 QNV---KDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVDKERQEVESKRDELEQETS 1971
Query: 3269 QLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEEL------KNEIEKKSTD 3430
+LR I D+++L+ N ++E K + + +
Sbjct: 1972 KLR---EDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTIFELEKEHLGLRENE 2028
Query: 3431 IDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDL 3610
+ K+ +EL +L + +EQ +A ++ +K +++++ E+ R
Sbjct: 2029 AEYKQKQIDELQNKLRMEKVQVEQMQADKDQQ----RKKAEYVKTARGRETTALEEQRQE 2084
Query: 3611 LNSLTEEHADLKKQFLSATEE---LQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQL 3781
+ SL EE+ +++KQ E+ +S+ + LE+ K KEKL D+ ++ Q
Sbjct: 2085 MESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKYKEKL---DKEYEDLQFQR 2141
Query: 3782 RAFE 3793
+ FE
Sbjct: 2142 QLFE 2145
Score = 78.6 bits (192), Expect = 2e-11
Identities = 237/1255 (18%), Positives = 486/1255 (38%), Gaps = 94/1255 (7%)
Frame = +2
Query: 293 LDTRKSLETKIAETLERMEIHEGDTANTLKN------MNFDLGQDNPGVPGLLEDIRNTK 454
L R+ +E ETL E E T++ M ++ + +E+I+ TK
Sbjct: 595 LRERQEIERIKHETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTK 654
Query: 455 DLLDTVESGL------------YVSNVVSDA-VLNGVVSAQEEEFKEALAAKDSENFLLN 595
+ ++ + L VS + A L + +EE + ++E L
Sbjct: 655 EQMEEAKVELEEEREDLERKRDLVSREIEQAEFLRNEILRVKEEMESRWRETETEEVELR 714
Query: 596 KKIEDLNHKIWSLEETLQYKEEVILSSHETI----SERDRLLKDFIHEKDLMQQRAQETE 763
K + ++ L E + ++ I S + D+L + +K ++ + E +
Sbjct: 715 AKTQHELERLEKLREETERSQKNIEESKIELMLWKESLDKLKGEMEEDKHVVIMQMNEAK 774
Query: 764 QKLASRDNEMMHMVLEKDNIILSLHK-----------QIELQSQNTQSLDCFR--RDEIE 904
K + + +E+ I +S K + ELQ Q+ + D FR E E
Sbjct: 775 AKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQHAEMEDWFRVVNKEKE 834
Query: 905 DQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHA--KEMSK-Q 1075
+ N+ + + E + Q++E + + E+ + +DEIQ +E KE+ + +
Sbjct: 835 EANLAK-LAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKKAEELEQINKEIQRAR 893
Query: 1076 AEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRI 1255
E+ K+ + +ES L+ + E F + Q+R+++ + D +
Sbjct: 894 QELEKMRYFEKES-----LQKMLEDTQQERVF------VEQVRSELLKNKADQDKCLFEM 942
Query: 1256 DFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKI---SENL 1426
D E +++ Q Q + K+ELE+ + ++ +E++
Sbjct: 943 DSERKELEQMRFQVENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDTESM 1002
Query: 1427 ERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQI 1606
R +L + + E AE + ++ ++ E+L
Sbjct: 1003 NRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRLLRKDMENEREDL---- 1058
Query: 1607 NIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEK------------SQKVLQSFESH 1750
+K E DT ++ ++ + EIE+ +K+ E
Sbjct: 1059 -------EKIRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEM 1111
Query: 1751 IEKL--VNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVA--VSQEQHI 1918
I K+ + + E++ L + ++ K++++ R + N++ A + Q++ I
Sbjct: 1112 IRKMEAMKREMGEIEDMKVELTKQKENIDMKMEHA----RLEMTNLEMMKADLLRQKEDI 1167
Query: 1919 EHQC-KEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDL 2095
E+Q + E +++ + R EE + +D + R + N LK + Q
Sbjct: 1168 ENQMLAAKSERQQMEVMRTEILKQKEDLEERLEEVIKENDRVEQMREDVNNALKDIDQAK 1227
Query: 2096 ELLKAEEAV--KSLSNNVGVSTKGIHYFSQLIQEG--KDGEASDVQGKSRALRRHSTGQA 2263
E ++ + V + V+TK Y ++ + G K ASD++ + + +
Sbjct: 1228 EDIQRQREVIAQEKVQPAIVATKSSEY-AKTEEPGAIKSYRASDLELSASIQKERQELEH 1286
Query: 2264 FREPPKPE--DLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHF 2437
++E E +L + K V+ + EE+ + + L+NW + QL
Sbjct: 1287 YKEIILKEKHELNKIKEDVKAVK-NDAEERMIKLHEEEKEMKTKRVSLQNWER-QLQTEK 1344
Query: 2438 KQSFAGLKREYELELQ-RKTEEIYDLKRL-LLNEKNGLHAXXXXXXXXXXXXVAEITGKF 2611
+++ GL + Q + ++ D+K L L +EK+ L V T
Sbjct: 1345 EKNQKGLDAIWNENQQLNERKQQLDIKELHLQSEKSKLEYKKPLEIKQVDAQVQ--TELM 1402
Query: 2612 EKVLQENKLLPVEEVQRYKM-LCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKK 2788
E + + L +EE+ + + L K+EL ++ ++ +++ E + + L+ L +A +
Sbjct: 1403 EDASEYDMALSIEELDKQRQFLEYFKQELLAQKCTMERQMAEIELSRDELS--LREATLQ 1460
Query: 2789 SADHAQRESHLLKHIADLEAGITDREIMTSVCS------DVLTALFVEMVREKEFSLSLA 2950
+A + L + E T E+ + D+ T + +E+ + L
Sbjct: 1461 TATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGWVDLQTQIAESREKEEMVRIELE 1520
Query: 2951 TKEQETVNQ--KQMSLRKMLEDKDKLLCLVGE-ENKEHKRQIA-----ILEKLKEETENN 3106
K ++ +N+ + + K + D L E EN E +R++ LE +K E +
Sbjct: 1521 -KARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQRKMMEDEKRALENMKYELQRE 1579
Query: 3107 PGRVFLQS----EEREKIEEQKRVLDQALQECEELKNDIQNKHS-------DIDSLREEQ 3253
G + +ER+ +E L Q +E E+ ++D+Q + D+++LRE
Sbjct: 1580 SGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERSREIKDLENLRELN 1639
Query: 3254 EKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDI 3433
E Q I + D ++ ++ N + K+EIE + + I
Sbjct: 1640 ELTLNQ------------------------IKTKSDVLE-KISELNSQQKDEIENEKSKI 1674
Query: 3434 DLLIKEKEELNERLAYTQKAMEQ-KEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDL 3610
+ + +++ L QK M+ + AV +EK L+ SQ EQ ++ D+
Sbjct: 1675 KIREYDLQQMQTDLNRQQKEMQDIQNAVFMEK--------SELKKSQDEIAEQLKQVGDM 1726
Query: 3611 LNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDL 3775
+ E +L ++ + E+ ERD+ + + L+ LV E L EK L
Sbjct: 1727 MQFTQNEKDNLDRERAAIIEQKLQMERDMTHLL--NRELESLKLVKKEVLNEKRL 1779
Score = 73.9 bits (180), Expect = 5e-10
Identities = 215/1271 (16%), Positives = 497/1271 (39%), Gaps = 103/1271 (8%)
Frame = +2
Query: 296 DTRKSLETKI---AETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLD 466
+ K ++T + A+ +E++++ ++ + ++ + L+E+I+ +D++D
Sbjct: 6902 EAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIKKKRDIID 6961
Query: 467 TVESGLYVSNVVSDAVLNGVVSAQEEEFKE------ALAAKDSENFLLNKKIEDLNHKIW 628
+ + ++ + + A+ + FK+ ALA + L K ++++
Sbjct: 6962 ESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQQKRNALEKMSKEISRDRM 7021
Query: 629 SLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVL 808
LE+ K+E+ L+ E +R+ D QR QE + L S +
Sbjct: 7022 KLEDE---KKEIQLAREEL----ERMHGDM--------QRQQEAKDHLLSG--------I 7058
Query: 809 EKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEH 988
++++ +I LQ R+ EI D + + ++V Q+ E+ +
Sbjct: 7059 TDESLLKKSEAEIVLQPSQVDKAKPARKTEISDSD---------KQPVFVQQMPEM-DLK 7108
Query: 989 DLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESL--FTAEIYE 1162
D L+ + + ++ +KD + K LE+ ++ ++ L AE+ +
Sbjct: 7109 DALKKDFESEKLDLPKVKDVLPQDQQMK----------LEQKLIEDEMDKLKQMRAELQK 7158
Query: 1163 NTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXX 1342
DQI + + DM ++ +D +A+R+ +L E+
Sbjct: 7159 EA-----DQIEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINIQ------------ 7201
Query: 1343 TLKASMEMQCSKLKDELEEERGKISENLERI-SKLQKMNNELAERSKSQNSIXXXXXXXX 1519
K + + Q + + E + ERI +++ + N ELA++ +
Sbjct: 7202 --KVNQQKQATAFQME--------KTDFERIKTEIDQANKELADQQE------------- 7238
Query: 1520 XXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQ 1699
K ++ ++ +++ A +S ++TI++ LS++
Sbjct: 7239 --------------------KNKKTITEMQKERETLEEMRANISKQVETITNENKSLSSR 7278
Query: 1700 KFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYS---LIHKVDNSGETLRAF 1870
+ E+ K Q+ + + +++L N + E+ C L+ R L +VD+ + +
Sbjct: 7279 ESELAKLQEDILQQQQEMDELKNTIMMEM----CQLDQRQSDIDLLQKEVDDLMDFTKTE 7334
Query: 1871 VKNIQNQ--VAVSQEQHIEHQCKE-ELEGHIAD---LVLNDFSNDILSWSRRKEEAVVHD 2032
+ N++ + ++Q ++I+ ++E + L LN+ D++ + +E +
Sbjct: 7335 MANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNE-EKDLIE--KERELLTKNL 7391
Query: 2033 DEFDAERIALLNELKSLHQDLELLKAEEA-VKSLSNNVGVSTKGIHYFSQLIQEGK---- 2197
D D +++ + EL++L + E +K E+ ++ + ++ G FS+ ++ +
Sbjct: 7392 DHTDKDKMDMKRELENLKVEKETIKNEKKELEKMKISLQRKAIGFKEFSEKTKDERPIVE 7451
Query: 2198 ----------DGEASDVQGKSRALRRHSTGQAFREPPKPEDLYT-------------TYS 2308
D +GK R T + R+ EDL+ Y
Sbjct: 7452 EMAAQFTRQLDISERPAEGKFIEERLDQTEKKRRKTYYTEDLFQEEKTDLQKTKEEINYD 7511
Query: 2309 EGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQR 2488
+I K+ + T++ + KE++ + + + ELQ
Sbjct: 7512 REEIYRQRTELNKEKETLKQMHTSNLKEIENIEKEKEKIQRTWNEL-----DQIRAELQN 7566
Query: 2489 KTEEIYDLKRLLLNEKNGL--HAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQR 2662
K ++ D +++ EK L E K K LQE +L E + +
Sbjct: 7567 KQRDMDDTTNIMMKEKAELARDLENLQNEKDELQKSRENIQKLMKELQEERLKTSEALNK 7626
Query: 2663 YKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLA-------------EKLSDALKKSAD-- 2797
+ EE++ K DSL + E D + L +K D ++S +
Sbjct: 7627 ERQQ--FTEEIKLKNDSLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDVRRQSDESD 7684
Query: 2798 ------HAQRES------HLLKHIADLEAGITD-----REIMTS-VCSDVLTALFVEMVR 2923
+RES +LK DLE + R + T + ++ + L E++
Sbjct: 7685 IARANLQRERESLDQLSVEILKQKQDLERERDELLEQWRLVETQKMDNENVKQLKTELLD 7744
Query: 2924 EKEFSLSLATKEQET---VNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEE 3094
EKE + + + ++ + + +++L K LE+ + + +E + +R L+ ++
Sbjct: 7745 EKESTEKIRKQLEQDKAYMEENKLNLHKELEELNLQKQGIQDERAQLERMKGELQMKADD 7804
Query: 3095 TENNPGRVFLQSEE-REKIEEQKRV---LDQALQECEELKNDIQNKHSDIDSLREEQEKL 3262
E + + ++ E+ E ++ LD+A E ++L +++ +++ + E +K
Sbjct: 7805 IERKMQEILYEKQKYAERKSENYKIQTYLDEANAEVQKLNKELERYDENLEKCKLELDKA 7864
Query: 3263 NKQLR-----CMXXXXXXXXXXXXXXXXXXXXISSNL-------DSMQLELRNYNEELKN 3406
+ I NL + + E+R ++EL
Sbjct: 7865 RAETERVKQGAKIPETQQIEQSLQKERDYIEDIRRNLFKKEEAIEKDKAEIRLRHQELDL 7924
Query: 3407 EIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATRE 3586
K + ++K+K E + +K +++ E L +K+ + +++++ L+ Q T
Sbjct: 7925 IQAKVVKQKEEMVKQKIESEREIQQEKKKLQRSEEELEDKMQKIKREMIELKLLQDETDG 7984
Query: 3587 QTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKE 3766
+ + + + + + +L+K + A E SK+ +++ M T+ + + + ++
Sbjct: 7985 KRKDVDNKMRQVARKRDELEK--MKADVESASKKLEVDRVMLNTERDELERIKTESQRAT 8042
Query: 3767 KDLQLRAFEIA 3799
+ +Q A E A
Sbjct: 8043 EHMQSHAEERA 8053
Score = 63.5 bits (153), Expect = 7e-07
Identities = 89/436 (20%), Positives = 190/436 (43%), Gaps = 38/436 (8%)
Frame = +2
Query: 2588 VAEITGKFEKVLQENKLLPVEEVQRYKMLCVLK----EELQSKIDSLLKE--------IK 2731
V ++ +QE + + +E+V R K + ++ E+ +S I ++E +K
Sbjct: 14677 VTKLEDTLTSEVQEMRDMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEETLK 14736
Query: 2732 EKDSNSKVLAEKLSDA--LKKSADHAQRESHLL-----KHIADLEAGIT----DREIMTS 2878
EK N + L + L D L + D +E + ++IA LE I D+E +
Sbjct: 14737 EKSRNEETLLQLLHDKDDLSNTLDEKSKEIENITVTFKRNIAQLETTIAMMKKDKE---N 14793
Query: 2879 VCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHK 3058
+ +++L E RE + + E+E ++K ++ + LED +E K+
Sbjct: 14794 IENELLQLKQTEQEREIQRGTDDTSNERENYDEK-VTYKTELEDS--------KEKKKPD 14844
Query: 3059 RQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHS---D 3229
R + L+ ++ G Q+ E K+++ ++ D Q+ EEL ++++NK +
Sbjct: 14845 RDSS-LKLTDADSAKTDGEREAQTLET-KVQDVLQLTDYTTQDQEELHDEMENKMKIILE 14902
Query: 3230 IDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNE----- 3394
++ +++ +KL ++ R + S + S+ E+ + +
Sbjct: 14903 LNEAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEM 14962
Query: 3395 ---ELKNEIEKKST----DIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKIL 3553
E+K +I+ +S + D+ I++ +E E + K E++ + K + +
Sbjct: 14963 QQIEIKMQIQTRSVATQWETDVQIQQGQEATETTGHITKKSEEEISAKKTK----QPTVT 15018
Query: 3554 LLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKE 3733
LE + ++ + ++ RD LN E+ A +K ++L+ + D++ M E + E
Sbjct: 15019 KLEDTLTS---EVQEMRDSLNKEMEDVARMKTIMKMEKDQLEQAKSDIQTQMEEFERNME 15075
Query: 3734 KLLVSDENLKEKDLQL 3781
+ + +EK LQL
Sbjct: 15076 EAMEEKSRNEEKLLQL 15091
>ref|XP_685984.6| PREDICTED: titin isoform X7 [Danio rerio]
Length = 15997
Score = 136 bits (343), Expect = 6e-29
Identities = 241/1198 (20%), Positives = 484/1198 (40%), Gaps = 108/1198 (9%)
Frame = +2
Query: 539 EEEFKEALAAKD---SENFLLNKKIEDLNHKIWSLE---ETLQYKEEVILSSHETISERD 700
E + KE L K+ S+ LL K +E+L K+ +E E+L+ E++ + E + +
Sbjct: 3628 EIQMKEVLTEKELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMK 3687
Query: 701 RLLKDFIHEKDLM----QQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNT 868
L+ E + + Q Q E+ A + ++ DNI +H + Q
Sbjct: 3688 TDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMK 3747
Query: 869 QSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDE 1048
Q D + + E QN+++E+EK+ + I + EL + L + D I+++K+E
Sbjct: 3748 QKQDELDQLKTEIQNLQQELEKE--KEIIMKDRSELDLKQSELDKQQTNMNDIIETMKNE 3805
Query: 1049 CHAKEMSKQA------EISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRND 1210
+ K+ EI K H ++ NS E L ++ + F E +++ Q++ +
Sbjct: 3806 RKQLDKDKEEMEEQKREIEKEKHDFDQG-RNSLDEDLKMMKLQKQVFEEEKNKLEQMKIE 3864
Query: 1211 MYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDE 1390
L E +++ K+K+E
Sbjct: 3865 -----------------LEREAGEIR-----------------------------KIKEE 3878
Query: 1391 LEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMA 1570
++ ER + + E + + ++ LAE +K + I
Sbjct: 3879 IQNERQSLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEK------ 3932
Query: 1571 FGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESH 1750
S EE+ + I+ + K+ + D + LQ + Q+ EIEK + ++S +
Sbjct: 3933 --SNFEEMRENISKQTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAA 3990
Query: 1751 IEKLVNDSLHEVDSAFCSLNSRFYSL---IHKVDNSGETLRAFVKNIQNQV----AVSQE 1909
I K+V D H++ SL+ SL +N E L+ ++ + + E
Sbjct: 3991 IIKIVEDLQHKI----ISLDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLE 4046
Query: 1910 QHIEHQCKEELEGHIA----------------DLVLNDFSNDILS--WSRRKEEAVVHDD 2035
+ Q EE+ I D+VLN+ + DI S + ++ ++ +
Sbjct: 4047 TQHDRQRVEEMTAQITKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKE 4106
Query: 2036 EFDAERIALLNELKSLHQDL---------ELLKAEEAVKSLSNNVGVSTKGIHYFSQLI- 2185
+ + E+ +EL + +DL E+ K E ++ ++ N+ + I + + +
Sbjct: 4107 KHNLEKTR--SELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQMK 4164
Query: 2186 --QEGKDGEASDVQGKSRALRRHS-------------TGQAFREPPKPEDLYTTY-SEGK 2317
Q+ D +++Q + L + + ++ D+ T +E K
Sbjct: 4165 QKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNERK 4224
Query: 2318 IVEPHPTEEKKLLAILAFETADASDSPLRNWPKE-QLLGHFKQSFAGLKREYE---LELQ 2485
+++ E ++ + E D D +++ ++ +++ KQ K + E ELQ
Sbjct: 4225 LLDKDKEEMEEQKQEMEKE-RDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQ 4283
Query: 2486 RKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXV--AEITGKFEKVLQENKLL---PVE 2650
R+ +EI +K NE+ L V AE T + +++L E ++ +
Sbjct: 4284 READEIRKIKEETQNERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMA 4343
Query: 2651 EVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKH 2830
++QR K + EE++ I ++I+ + SK+ ++L L+ Q E + K
Sbjct: 4344 DLQREKRIL---EEMRENISKQTEDIENEKEKSKLREDELK-KLQTEVQKQQSEIDMEKT 4399
Query: 2831 IADLEAGITDRE---IMTSV--CSDVLTALFVEMVREKEF---SLSLATKEQETVNQKQM 2986
+ E + RE +MT + S+ + E++ EKE +L K+ E + QK M
Sbjct: 4400 NIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLM 4459
Query: 2987 SLRKMLEDKDKLLCLVGEEN---KEHKRQIAI----LEKLKEETENNPGRVFLQSEEREK 3145
S+ + E G E K+ K + I +EK+K ET+++ RV E+ +
Sbjct: 4460 SIERDSESLKLDREAFGNEKEVLKQMKTDLQIQADEIEKIKLETQHDRQRV---EEKTAQ 4516
Query: 3146 IEEQKRVLDQALQE-------CEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXX 3304
I++ + ++ + E E+ DI+ K I S++ +++ L K+
Sbjct: 4517 IQKDRDEINNLIVETNRKDMVLNEMDRDIEEK---IKSIQSDKDMLEKE----------- 4562
Query: 3305 XXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYT 3484
NL+ + EL E L+ + E + DI+ + K + +
Sbjct: 4563 --------------RHNLEKTRSELARAKENLETQREIERKDIEKMKKNISREMHEIKHQ 4608
Query: 3485 QKAMEQKEAVL---------VEKLFEGEQKILLLESSQSATRE-QTEKYRDLLNSLTEEH 3634
++ M+QK+ L +++ E E++I++ SQ R+ + +K + +N + E
Sbjct: 4609 EEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETM 4668
Query: 3635 ADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSE 3808
+ +KQ EE + +++++E + ++ L DE+LK LQ + E S+
Sbjct: 4669 KNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSL---DEDLKMMKLQKQVIEEEKSK 4723
Score = 124 bits (310), Expect = 4e-25
Identities = 247/1298 (19%), Positives = 522/1298 (40%), Gaps = 115/1298 (8%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNT 451
IE E L+ K K A+ + +++ + L+ M +L ++ L ED +
Sbjct: 4977 IEEEKNKLEQMKIELEKEADEIRKIKEETQNERQRLEKMTEELKKEKESFTHLAEDTKTE 5036
Query: 452 KDLLDTV-------------------ESGLYVSNVVSDAV---------------LNGVV 529
K +LD + E +S D+ L +
Sbjct: 5037 KKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQLQAEI 5096
Query: 530 SAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLE---ETLQYKEEVILSSHETISERD 700
Q+ E K + +SE + K ++DL HK++SL+ E+L+ E + E + +
Sbjct: 5097 HKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREVLKQIK 5156
Query: 701 RLLKDFIHEKDLMQQRAQETEQKLAS--------RD--NEMMHMVLEKDNIILSLHKQIE 850
LK E + ++ Q Q++ RD N ++ KD ++ + +I+
Sbjct: 5157 TDLKRKAEEIEKIKLETQHDRQRVEEMTAQIQKERDKINNLIEETNRKDMVLNEIKTEIK 5216
Query: 851 LQSQNTQSLDCFRRDEIEDQN------------IKEEIEKQIVETIYVTQIQELGEE--- 985
+ + +S RD +E + KE +EKQ I + +IQ+ E+
Sbjct: 5217 EKIKAIES----DRDMLEKEKHDLEKTRSKLLRAKENLEKQ--RKIKLAEIQKEREDLEK 5270
Query: 986 ---------HDLLRLESA--KYQDEIQSLKDECH--AKEMSKQAEISKLSHTLEESIMNS 1126
HD+ E + QDE+ LK E +E+ K+ EI + + + S
Sbjct: 5271 MNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRS-QLDLRQS 5329
Query: 1127 NLESLFT-----AEIYENTFRELG---DQISQLRNDMYSKNSYIDSLASRIDFLSSECNK 1282
L+ T E +N ++L ++ + + +M + D +D + K
Sbjct: 5330 ELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDE-DLKMMK 5388
Query: 1283 LQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISK-LQKMNN 1459
LQ+Q +A ++ K+K+E++ ER +NLE++++ L++
Sbjct: 5389 LQKQVLEDEKSKLEQMKIELEREA---VEIRKIKEEIQNER----QNLEKMTEALKEERE 5441
Query: 1460 ELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKE 1639
+LAE +K N + S LEE+ + I+ ++ K+
Sbjct: 5442 DLAEETKKNNQVLDEMKVANESTLADILREK--------SNLEEMRENISKQTEDVENKK 5493
Query: 1640 AEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEV-----DSAFCS 1804
+ D + LQ + Q+ EIEK + ++S + I K V D H++ D+
Sbjct: 5494 ENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLK 5553
Query: 1805 LNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFS- 1981
L+ + +N E L+ ++ + ++ +E Q + +A + D
Sbjct: 5554 LDREAF------ENEKEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDE 5607
Query: 1982 -NDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTK 2158
N+++ + RK+ V+++ D E ++KS+ D ++L+ E+ +++ +
Sbjct: 5608 INNLIEETNRKD-MVLNEKNRDIEE-----KIKSIQSDKDMLEKEK------HDLEKTRS 5655
Query: 2159 GIHYFSQLIQEGKDGEASDVQGKSRALRRHSTG----------QAFREPPKPEDLYTTYS 2308
++ + +++ K+ +++Q + L + + Q + K ++L +
Sbjct: 5656 ELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKT 5715
Query: 2309 EGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQR 2488
E + ++ +EK+++ D S LR ++ + +K E + +L +
Sbjct: 5716 EIQNLQQELEKEKEIIM------KDRSQLDLRQSELDKQQTNMNDIMETMKNERK-QLDK 5768
Query: 2489 KTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYK 2668
EE+ + K+ + E++ + + + +K ++ K + EE + +
Sbjct: 5769 DKEEMEEQKQEMEKERDNMDQSR------------KSLDEDQKKMKLQKQMFEEEKNKLE 5816
Query: 2669 MLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDAL---KKSADHAQRESHLLKHIAD 2839
+ K EL+ + D + K IKE+ N + EK+++ L K+S H ++ K I D
Sbjct: 5817 QM---KIELEREADEISK-IKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILD 5872
Query: 2840 LEAGITDREIMTSVCSD--VLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDK 3013
E + + M + + +L + + + KE+ E+E ++ L+K+ +
Sbjct: 5873 -EMKVANESSMADLQREKSILEEMRENISKLKEY----IDNEKEKSKLREDELKKLQTEV 5927
Query: 3014 DKLLCLVGEE--NKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQE 3187
K + E N E +R I EK + +E ++K E+ + + + L E
Sbjct: 5928 QKQQSKIDMEKTNIESERAAMIREKQN-----------MMTELKKKSEDVEIQMKEILTE 5976
Query: 3188 CEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSM 3367
E L ND + D+++L+++ L + + + + D +
Sbjct: 5977 KELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEI 6036
Query: 3368 QLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQK 3547
+ +++ + + +E+ + I KE++++N + T + K+ VL EK + E+K
Sbjct: 6037 E-KIKLETQHDRQRVEEMAAQIQ---KERDKINNLIEETNR----KDMVLNEKNRDIEEK 6088
Query: 3548 ILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEV-------A 3706
I ++S + ++ + L + DL+KQ + E+Q + D+E
Sbjct: 6089 IKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENITRE 6148
Query: 3707 MTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQYQ 3820
M E K +E++ N K+ +L EI N +++ +
Sbjct: 6149 MHEIKHQEEQM-----NQKQDELDQLKTEIQNLQQELE 6181
Score = 122 bits (307), Expect = 9e-25
Identities = 261/1290 (20%), Positives = 533/1290 (41%), Gaps = 129/1290 (10%)
Frame = +2
Query: 296 DTRKSLETKIAETLERMEIH----EGDTANTLK---NMNFDLGQDNPGVPGLLEDIRNTK 454
D K L+T++ + ++++ E + A ++ NM +L + + V +++I K
Sbjct: 5918 DELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEIQMKEILTEK 5977
Query: 455 DLLDTVESGLY--VSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIW 628
+LL L V N+ + + + K A ++E + + DL +
Sbjct: 5978 ELLHNDRKLLTRDVENLQQKLI---DLERDSKRLKLDREAFENEKEAMKQMKTDLQIQAD 6034
Query: 629 SLE----ETLQYKEEVILSSHETISERDRL--LKDFIHEKDL-MQQRAQETEQKLASRDN 787
+E ET ++ V + + ERD++ L + + KD+ + ++ ++ E+K+ S +
Sbjct: 6035 EIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQS 6094
Query: 788 EMMHMVLEKDNI------ILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVET 949
+ + E+ N+ + + + +E Q +NT + R+++E N E I +++ E
Sbjct: 6095 DKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKMN--ENITREMHEI 6152
Query: 950 IYVT-QIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMS----KQAEISKLSHTLEES 1114
+ Q+ + +E D L+ E Q E++ K E K+ S +Q+E+ K +++
Sbjct: 6153 KHQEEQMNQKQDELDQLKTEIQNLQQELEKEK-EIIMKDRSQFDLRQSELDK-----QQT 6206
Query: 1115 IMNSNLESLFTAEIYENTFRELG---DQISQLRNDMYSKNSYIDSLASRIDFLSSECNKL 1285
MN +E++ +N ++L +++ + + +M + D +D + KL
Sbjct: 6207 NMNDIMETM------KNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLD-KDLKMMKL 6259
Query: 1286 QEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNEL 1465
Q+Q +A + K+K+E + ER + + E + K ++ L
Sbjct: 6260 QKQVFEEEKNKLEQMKIELEREAD---EIRKIKEETQNERQSLEKMTEELKKEKESFTHL 6316
Query: 1466 AERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAE 1645
AE +K + I S LEE+ + I+ ++ K+
Sbjct: 6317 AEDTKKEQEILDKVKVANESLMADLQKEK--------SNLEEMRENISKQTEDVENKKEN 6368
Query: 1646 VSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEV-----DSAFCSLN 1810
+ D + LQ + Q+ EIEK + ++S + I K V D H++ DS L+
Sbjct: 6369 LRLREDELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLD 6428
Query: 1811 SRFYSLIHKVDNSGETLRAFVKNIQNQV----AVSQEQHIEHQCKEELEGHIADLVLNDF 1978
+ +N E L+ ++ + + E + Q EE+ I D
Sbjct: 6429 REAF------ENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQK--DRDK 6480
Query: 1979 SNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTK 2158
N+++ + RK + V+++ D E+ ++KS+ D ++L+ E+ +++ +
Sbjct: 6481 INNLIEETNRK-DMVLNEKNRDIEK-----KIKSIQSDKDMLEKEK------HDLEKTRS 6528
Query: 2159 GIHYFSQLIQEGKDGEASDVQGKSRALRRHSTG----------QAFREPPKPEDLYTTYS 2308
++ + +++ K+ + +Q + L + + Q + K ++L +
Sbjct: 6529 ELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKT 6588
Query: 2309 EGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQR 2488
E + ++ +EK+++ + A D S L K+Q + +K E + +L +
Sbjct: 6589 EIQNLQQELEKEKEII-MKARSQLDRRQSEL---DKQQT--NMNDIMETMKNERK-QLDK 6641
Query: 2489 KTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYK 2668
EE+ + K+ + E++ + K+++ K + EE + +
Sbjct: 6642 DKEEMEEQKQEMEKERDNMDQSRKSLDEDL------------KMMKLQKQVIEEEKNKLE 6689
Query: 2669 MLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKS-------ADHAQRESHLL- 2824
+K EL+ + D +++IKE+ N + + EK+++ LKK A+ +RE + L
Sbjct: 6690 Q---MKIELEREADD-IRKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTKREKNSLD 6745
Query: 2825 -------KHIADLEAGITDREIMTSVCSDVLTALFVE----MVREKEF---------SLS 2944
+ADL+ ++ E M S + E +RE E S
Sbjct: 6746 EMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQS 6805
Query: 2945 LATKEQETVNQKQMSLRKMLED-KDKLLCL------------VGEENKEHKRQIAI---- 3073
E+ + +++ ++ K +ED + K++ L E KE +Q+
Sbjct: 6806 ETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELER 6865
Query: 3074 ----LEKLKEETENNPGRV------FLQ--SEEREKIEEQKRVLDQALQECEELKNDIQN 3217
+EK+K ET++ RV F++ + ER+++++ K ++++ QE E+ ++D+
Sbjct: 6866 EADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQ 6925
Query: 3218 KHSDIDS-----------LREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDS 3364
+D L EE+ KL + M NL+
Sbjct: 6926 SRKSLDEDLKMMKAQKQVLEEEKNKLEQ----MKIGLEREADEISKIKEETQNERQNLEK 6981
Query: 3365 MQLELRNYNEELKNEIEKKSTDIDL-----------LIKEKEELNERLAYTQKAMEQKEA 3511
M L+ E L EI++K+ +D L KEK L E K +E E
Sbjct: 6982 MANALKEEREYLAEEIKRKNQVLDKIKVANESTLADLQKEKRILEEMRENISKQIEDIEN 7041
Query: 3512 VLVE-KLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKE 3688
+ KL E E K L E + + EK ++ E A + ++ + EL+ K
Sbjct: 7042 EKEKSKLREDELKKLQTEVQKQQSEIDMEK-----TNIESERAAMIREKQNMMTELKKKS 7096
Query: 3689 RDLEVAMTETKFLKEKLLVSDENLKEKDLQ 3778
D+E+ M E KE LL +D NL +KD++
Sbjct: 7097 EDVEMQMKEILTEKE-LLHNDRNLLKKDVE 7125
Score = 115 bits (287), Expect = 2e-22
Identities = 245/1253 (19%), Positives = 499/1253 (39%), Gaps = 71/1253 (5%)
Frame = +2
Query: 275 EVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTK 454
E ED +T+K+ + L+ M++ T + +L + + ED+ N K
Sbjct: 5439 EREDLAEETKKN-----NQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKK 5493
Query: 455 DLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSL 634
+ L E L L + Q+ E ++ +SE + K +EDL HKI L
Sbjct: 5494 ENLRLREDEL--------RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICL 5545
Query: 635 E---ETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMV 805
+ E+L+ E + E + + L+ E + ++ Q Q++ E M
Sbjct: 5546 DRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIKLETQHDRQRV-----EEMAAQ 5600
Query: 806 LEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEE 985
++KD ++ IE ++ L+ RD IE++ + +K ++E E+
Sbjct: 5601 IQKDRD--EINNLIEETNRKDMVLNEKNRD-IEEKIKSIQSDKDMLEK----------EK 5647
Query: 986 HDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYEN 1165
HDL K + E+ +K++ ++ + AEI K LE+ MN N+ T E++E
Sbjct: 5648 HDL-----EKTRSELYKVKEDLEKQKENTLAEIQKEREDLEK--MNENI----TREMHEI 5696
Query: 1166 TFRE------------LGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXX 1309
+E L +I L+ ++ + I S++D SE +K Q
Sbjct: 5697 KHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIM 5756
Query: 1310 XXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISEN---LERISKLQKMNNELAERSK 1480
K ME Q K E+E+ER + ++ L+ K K+ ++ E K
Sbjct: 5757 ETMKNERKQLDKDKEEMEEQ----KQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEK 5812
Query: 1481 SQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHL 1660
N + N +LE++T+++ +E E HL
Sbjct: 5813 --NKLEQMKIELEREADEISKIKEETQNKR--QRLEKMTEELI--------REKESLAHL 5860
Query: 1661 -DTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHK 1837
+ + + +L K E S LQ +S +E++ L
Sbjct: 5861 AEDTKTEKKILDEMKVANESSMADLQREKSILEEM---------------RENISKLKEY 5905
Query: 1838 VDNSGETLRAFVKNIQN-QVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKE 2014
+DN E + ++ Q V ++Q K +E A ++ + N + ++ E
Sbjct: 5906 IDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMI-REKQNMMTELKKKSE 5964
Query: 2015 EAVVHDDEFDAERIALLNELKSLHQDLELLKAEEA-VKSLSNNVGVSTKGIHYFSQLIQE 2191
+ + E E+ L N+ K L +D+E L+ + ++ S + + + + +++
Sbjct: 5965 DVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQ 6024
Query: 2192 GKDG---EASDVQGKSRALRRHS-------TGQAFREPPKPEDLYTTYSEGKIV--EPHP 2335
K +A +++ K + +H Q +E K +L + +V E +
Sbjct: 6025 MKTDLQIQADEIE-KIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNR 6083
Query: 2336 TEEKKLLAILAFETADASDSPLRNWPKEQL-LGHFKQSFAGLKREYELELQRKTEEIYDL 2512
E+K+ +I + + D + N K + L K+ K E+Q++ E++ +
Sbjct: 6084 DIEEKIKSIQSDK--DMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKM 6141
Query: 2513 KRLLLNEKNGL---HAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQ---RYKML 2674
+ E + + EI +++ +E +++ + Q R L
Sbjct: 6142 NENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQFDLRQSEL 6201
Query: 2675 CVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGI 2854
+ + ++++ E K+ D + + + E+ + K+ D Q L K DL+
Sbjct: 6202 DKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDK---DLKMMK 6258
Query: 2855 TDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLV 3034
+++ + L + +E+ RE + + ++ET N++Q SL KM E+ K
Sbjct: 6259 LQKQVFEEE-KNKLEQMKIELEREAD---EIRKIKEETQNERQ-SLEKMTEELKKEKESF 6313
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQ 3214
++ K++ IL+K+K E+ + +E+ +EE + + + ++ E K +++
Sbjct: 6314 THLAEDTKKEQEILDKVKVANESLMADL---QKEKSNLEEMRENISKQTEDVENKKENLR 6370
Query: 3215 NKHSDIDSLREEQEKLNKQLRC--MXXXXXXXXXXXXXXXXXXXXISSNLDSMQLEL--- 3379
+ ++ L+ E K +++ + IS + DS L+L
Sbjct: 6371 LREDELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDRE 6430
Query: 3380 -----RNYNEELKNEIEKKSTDIDLLIKE----KEELNERLAYTQKAME----------Q 3502
R +++K E+E+++ +I+ + E ++ + E A QK + +
Sbjct: 6431 AFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNR 6490
Query: 3503 KEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQS 3682
K+ VL EK + E+KI ++S + ++ + L + DL+KQ + ++Q
Sbjct: 6491 KDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQK 6550
Query: 3683 KERDLEV-------AMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQYQ 3820
+ DLE M E K +E++ N K+ +L EI N +++ +
Sbjct: 6551 EREDLEKMNENITREMHEIKHQEEQM-----NQKQDELDQLKTEIQNLQQELE 6598
Score = 114 bits (285), Expect = 3e-22
Identities = 238/1256 (18%), Positives = 500/1256 (39%), Gaps = 82/1256 (6%)
Frame = +2
Query: 287 GGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLD 466
GGL T + LE+M+ + ++M L ++ + L +DI K+ D
Sbjct: 9115 GGLKTEIENTKRDKSNLEKMKAELEEKQQEEESMREILQKEKEELEQLKKDINREKE--D 9172
Query: 467 TVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETL 646
S V + + + + G Q+ +KE L E + +E LN + L +TL
Sbjct: 9173 IEISRELVESEIYEGEVKGFTDVQK--YKEELQIVTEELLTKKRNLEQLNSDVQHLMQTL 9230
Query: 647 QYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQK-LASRDNEMMHMVLEKDNI 823
EEV + + +E + + + + +++++ ++ E+ + EMM + LE N+
Sbjct: 9231 ---EEVDIQYIKKKAELEHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINM 9287
Query: 824 -ILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLR 1000
IL + +E + +N RR++ E + + E+++Q E + Q L E D +
Sbjct: 9288 EILQKREDMEKEKEN------LRREKQETELFRGELQRQRDEV--ESSRQALIMEKDQFK 9339
Query: 1001 LESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFREL 1180
L+ ++E+ + ++ H + + + ++ L ES+ N ++
Sbjct: 9340 LKIDHQRNEMSAAFEKEHKRLENMENDLENQRAKLAESL---------------NDAAKM 9384
Query: 1181 GDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASM 1360
++ Q++N++ + ++ + + +E K++++ L+
Sbjct: 9385 EQKLQQMKNELNKEKEQVEEMKQMV---KTERVKIEQEKEEMRKQTQEIEDGHEKLQKKT 9441
Query: 1361 EMQCSKLKD-ELEEERGK-ISENLE-RISKLQKMNNELAERSKSQNSIXXXXXXXXXXXX 1531
E+ L+D E +R K +S L+ + ++K N E+ + +S + +
Sbjct: 9442 EIADKLLQDANSESDRLKDLSMKLQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLK 9501
Query: 1532 XXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEI 1711
+ + E + + ++ ++ ++E + K +I
Sbjct: 9502 NDRDAYEKDMTHLELKREELVRETEDLERKILQQREQDEMA---------------KRDI 9546
Query: 1712 EKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQ 1891
E + L+ + I K N+ E+++ +S K+ L++ ++N+
Sbjct: 9547 ENQTEALEVMKVDILKKRNEFAKEMENV--------HSERQKLLLLQGALQSQESELENR 9598
Query: 1892 VAVSQEQHIEH------QCKEELEGHIADLVL---NDFSNDILSWSRRKEEAVVHDDEFD 2044
V + +++H++ +C+++L +++ V N++ I R KE+ + ++ +
Sbjct: 9599 VFMEEQKHLKQAKAETEECRKQL-AEMSETVTTEQNEYRKLIEELQREKEQLEISKNQIE 9657
Query: 2045 AERIALLNELKSLHQDLELLKAEEA----VKSLSNNVGVSTKGIHYFSQLIQEGKDGEAS 2212
E+ L N +L + LE L+ E+A K+ + +K I + +E +
Sbjct: 9658 QEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWV 9717
Query: 2213 DVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAIL--AFETADA 2386
+++G+ + + E + +E H E KK+ + L + E ++
Sbjct: 9718 EIEGEKKRMEE---------------------ETRRLEMHREEIKKVDSELQKSRENIES 9756
Query: 2387 SDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDL---KRLLLNEKNGLHAXX 2557
+ + N +E L K K E E E QR + DL K + +++
Sbjct: 9757 REEKINNKMEELL--QMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDII 9814
Query: 2558 XXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKM-LCVLKEELQSKIDSLLKEIKE 2734
+ K K L E L V++++ + K+E++ L KE +E
Sbjct: 9815 DIKIQEKEREIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQE 9874
Query: 2735 KDSNSKVLAEKLSD----------------ALKKSADHAQRESHLLKHIADLE-AGITDR 2863
K L +++ D ALK + ++E+ ++K LE + I +
Sbjct: 9875 LKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEM 9934
Query: 2864 EIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQM---SLRKMLEDKDKLLCLV 3034
++ + E +EKE SL + ET QKQM S KM+E+K+++ L
Sbjct: 9935 QLKIFKQQRLNDQTREENKKEKE---SLEQQRFETEQQKQMLEISTTKMMEEKNEMADLS 9991
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVF-LQSE---EREKIEEQKRVLDQALQECEELK 3202
E K LEK+ +T V +Q+E + + IE+Q +++ EE +
Sbjct: 9992 RELQKAKDE----LEKIAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEKE 10047
Query: 3203 NDIQNKHSDI--------------DSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXX 3340
IQ K +I +++ EE K L M
Sbjct: 10048 LSIQRKEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQKNNKDFELLE 10107
Query: 3341 XISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEA--- 3511
I S L++ + +L+ + E+ K+ +E + +++ KEKE L + Q EQ E
Sbjct: 10108 KIRSELENEKYDLQIWTEQQKHLVEVQLQELE---KEKERLEKMEIELQSKREQTEKEKA 10164
Query: 3512 --------------VLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLK- 3646
V+ +K + + LE+ ++ +E+ EK + L EE ++
Sbjct: 10165 DLNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQI 10224
Query: 3647 --KQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSE 3808
+ EE++ ++ LE++ + K +KE+ + E + K + +I N+E
Sbjct: 10225 EAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEE-QIQNNE 10279
Score = 114 bits (284), Expect = 4e-22
Identities = 214/1216 (17%), Positives = 493/1216 (40%), Gaps = 33/1216 (2%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNT 451
+E E L+ +S K+ E LE+ + +T ++ DL + N + + +I++
Sbjct: 4103 LEKEKHNLEKTRSELYKVKEDLEKQK---ENTLAEIQKEREDLEKMNENITIEMHEIKHQ 4159
Query: 452 KDLLDTVESGLYVSNVVSDAVLNGVVSAQEE--EFKEALAAKDSENFLLNKKIEDLNHKI 625
++ + + L D + + + Q+E + KE + SE L +++ +
Sbjct: 4160 EEQMKQKQDEL-------DQLKTEIQNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNM 4212
Query: 626 WSLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMV 805
+ ET++ + +++ E + E +K M++ +Q + S D ++ M
Sbjct: 4213 NDIIETMKNERKLLDKDKEEMEE----------QKQEMEKERDNMDQSIKSLDEDLKMMK 4262
Query: 806 LEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEE 985
L+K I +K +++ + + D R+ + E QN ++ +EK I E
Sbjct: 4263 LQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQNERQSLEKMTKALIK--------ER 4314
Query: 986 HDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESL-FTAEIYE 1162
DL+ L A+Y + + DE S A++ + LEE N + ++ E +
Sbjct: 4315 EDLVHL--AEYTKREKEMLDEMQVANKSSMADLQREKRILEEMRENISKQTEDIENEKEK 4372
Query: 1163 NTFRELGDQISQLRNDMYSKNSYIDSLASRID----FLSSECNKLQEQXXXXXXXXXXXX 1330
+ RE D++ +L+ ++ + S ID + I+ + E + +
Sbjct: 4373 SKLRE--DELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQNMMTELKKKSEDVEIQM 4430
Query: 1331 XXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXX 1510
T K +E + LK ++E+ + K+ ++ER S+ K++ E
Sbjct: 4431 KEILTEKELLENDSNLLKKDMEDLKQKLM-SIERDSESLKLDRE---------------- 4473
Query: 1511 XXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVL 1690
AFG++ E V+ + + ++ D I ++
Sbjct: 4474 -------------------AFGNEKE-----------VLKQMKTDLQIQADEIEKIKLET 4503
Query: 1691 SNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAF 1870
+ + +E+ +Q I L+ ++ + D ++ I + + + L
Sbjct: 4504 QHDRQRVEEKTAQIQKDRDEINNLIVET-NRKDMVLNEMDRDIEEKIKSIQSDKDMLEKE 4562
Query: 1871 VKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAE 2050
N++ + + + E+E + + + S ++ ++E+ DE D
Sbjct: 4563 RHNLEKTRSELARAKENLETQREIERKDIEKMKKNISREMHEIKHQEEQMKQKQDELDQ- 4621
Query: 2051 RIALLNELKSLHQDLE-----LLKAEEAVKSLSNNVGVSTKGIHYFSQLI-----QEGKD 2200
L E+++L Q+LE ++KA + + + ++ + + Q KD
Sbjct: 4622 ---LKTEIQNLQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKD 4678
Query: 2201 GEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETA 2380
E ++ Q + +H Q+ + EDL + +++E ++ K++ L E
Sbjct: 4679 KEETEEQKQEMEKEKHDFDQSRKS--LDEDLKMMKLQKQVIEEEKSKLKQMKIELEREAD 4736
Query: 2381 DASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRL-------LLNEKN 2539
+ + Q+ ++ + + + +RK + + ++K +L E++
Sbjct: 4737 EIRKVKEETQNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRERS 4796
Query: 2540 GLHAXXXXXXXXXXXXVAEITGKFEKV-LQENKL--LPVEEVQRYKMLCVLKEELQSKID 2710
L ++ K EK+ L+E KL L E ++ K ++ +
Sbjct: 4797 NLQEMRENISKQ----TEDVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNIERERA 4852
Query: 2711 SLLKEIKEKDSNSKVLA-EKLSDALKKSADHAQRESHLLKHI-ADLEAGITDREIMTSVC 2884
+++K+++ D SK+++ ++ +++LK + + E LK + +LE RE
Sbjct: 4853 AIIKDVE--DLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELE-----RE------ 4899
Query: 2885 SDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQ 3064
+D + + +E E++ + ET+N ++ L K E+ E+ +E +++
Sbjct: 4900 ADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQ-------EQKQEMEKE 4952
Query: 3065 IAILEKLKEETENNPGRVFLQS----EEREKIEEQKRVLDQALQECEELKNDIQNKHSDI 3232
+++ ++ + N + LQ EE+ K+E+ K L++ E ++K + QN+ +
Sbjct: 4953 RHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEADEIRKIKEETQNERQRL 5012
Query: 3233 DSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEI 3412
+ + EE +K + + + ++L + L EE++ I
Sbjct: 5013 EKMTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNL----EEMRENI 5068
Query: 3413 EKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQT 3592
K++ D + KEKE++ R + +EQ +A + ++ +GE K +E S + +
Sbjct: 5069 SKQTEDSE---KEKEKIRLR----EDELEQLQAEIHKQ--QGEIK---MEKSNNESERA- 5115
Query: 3593 EKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKD 3772
++ ++ DL+ + S +L+S + D E E + LK+ + +D K ++
Sbjct: 5116 --------AIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREVLKQ--IKTDLKRKAEE 5165
Query: 3773 LQLRAFEIANSEKQYQ 3820
++ E + ++ +
Sbjct: 5166 IEKIKLETQHDRQRVE 5181
Score = 114 bits (284), Expect = 4e-22
Identities = 231/1252 (18%), Positives = 504/1252 (40%), Gaps = 81/1252 (6%)
Frame = +2
Query: 302 RKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESG 481
R L+ + +E L++ + + D T+KN L +D + +++ +D +D
Sbjct: 5735 RSQLDLRQSE-LDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKS 5793
Query: 482 LYVSNVVSDAVLNGVVSAQE----EEFKEALAAKDSENFLLNKKIEDLNHKIWSL-EETL 646
L L + +E E+ K L + E + ++ ++ ++ + EE +
Sbjct: 5794 LDEDQ--KKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELI 5851
Query: 647 QYKEEVILSSHETISERDRL----------LKDFIHEKDLMQQRAQETEQKLASRDNEMM 796
+ KE + + +T +E+ L + D EK ++++ + + DNE
Sbjct: 5852 REKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENISKLKEYIDNEKE 5911
Query: 797 HMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIED---------QNIKEEIEKQIVET 949
L +D + K+++ + Q QS + IE QN+ E++K+ +
Sbjct: 5912 KSKLREDEL-----KKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKKSEDV 5966
Query: 950 IYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEM-SKQAEISKLSHTLEESIMNS 1126
Q++E+ E +LL + ++++L+ + E SK+ ++ + + E+ M
Sbjct: 5967 --EIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQ 6024
Query: 1127 NLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXX 1306
L + D+I +++ + ++ +A++I + N L E+
Sbjct: 6025 MKTDL----------QIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRK 6074
Query: 1307 XXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQK-----MNNELAE 1471
S++ KD LE+ER + + + K+++ N LAE
Sbjct: 6075 DMVLNEKNRDIEEKIKSIQSD----KDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAE 6130
Query: 1472 RSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVS 1651
K + + E++ + I I +E +++
Sbjct: 6131 IQKEREDV------------------------------EKMNENITREMHEIKHQEEQMN 6160
Query: 1652 GHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLI 1831
D + L+T + N + E+EK ++++ S + + E+D ++N ++
Sbjct: 6161 QKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQFDLRQS----ELDKQQTNMND----IM 6212
Query: 1832 HKVDNSGETLRAFVKNIQNQVA-VSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRR 2008
+ N + L + ++ Q + +E+H Q ++ L+ DL + + +
Sbjct: 6213 ETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLD---KDLKMMKLQKQVFEEEKN 6269
Query: 2009 KEEAVVHDDEFDAERIALL-----NELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYF 2173
K E + + E +A+ I + NE +SL + E LK E K ++ TK
Sbjct: 6270 KLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKE---KESFTHLAEDTKKEQEI 6326
Query: 2174 SQLIQEGKDGEASDVQGKSRAL---RRHSTGQAFREPPKPEDLYTT-----------YSE 2311
++ + +D+Q + L R + + Q K E+L Y +
Sbjct: 6327 LDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQ 6386
Query: 2312 GKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLK---REYELEL 2482
+ +E + A + D + + L +++F + ++ + EL
Sbjct: 6387 QREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTEL 6446
Query: 2483 QRKTEEIYDLKRLLLNEKNGLH--AXXXXXXXXXXXXVAEITGKFEKVLQENKL---LPV 2647
+R+ +EI +K +++ + + E T + + VL E +
Sbjct: 6447 EREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKI 6506
Query: 2648 EEVQRYK-MLCVLKEELQSKIDSLLK---EIKEKDSNSKVLAEKLSDALKKSADHAQRES 2815
+ +Q K ML K +L+ L K +++++ N+ +K + L+K ++ RE
Sbjct: 6507 KSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREM 6566
Query: 2816 HLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSL---SLATKEQETVNQKQM 2986
H +KH E + ++ + L E+ +EKE + S + Q ++++Q
Sbjct: 6567 HEIKH---QEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQT 6623
Query: 2987 SLRKMLE---------DKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQS--- 3130
++ ++E DKDK + E+ +E +++ +++ ++ + + + LQ
Sbjct: 6624 NMNDIMETMKNERKQLDKDKEE--MEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVI 6681
Query: 3131 -EEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXX 3307
EE+ K+E+ K L++ + ++K + QNK ++ + EE +K K + +
Sbjct: 6682 EEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTKREK 6741
Query: 3308 XXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQ 3487
S++ +Q E N EE+K I K++ DI+ KEK+++ R +
Sbjct: 6742 NSLDEMKVAN---ESSMADLQKEKSNL-EEMKENISKQTEDIE---KEKDKIRLR----E 6790
Query: 3488 KAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLK---KQFL 3658
+EQ +A + ++ E E + +E ++A + E + + SL + LK + F
Sbjct: 6791 DELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFE 6850
Query: 3659 SATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQ 3814
+ EEL+ + +LE E + K KL E + +++ E N+E++
Sbjct: 6851 NEKEELKQMKTELEREADEIE--KIKLETQHERQRVEEMTADFMETMNNERK 6900
Score = 111 bits (277), Expect = 3e-21
Identities = 233/1162 (20%), Positives = 476/1162 (40%), Gaps = 76/1162 (6%)
Frame = +2
Query: 524 VVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDR 703
+V+ +EE K+ ++S N + KK +L H+ L + Q E++I S + + +R
Sbjct: 13599 LVNMEEEIKKQRRVLEESMNEMTKKK-SELQHERSELYKQKQQLEDMIASESKRDVDTER 13657
Query: 704 LLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDC 883
+D E+ L ++R + + K +L++ + + ++I + ++ + +
Sbjct: 13658 SRQDKEDEQILKREREEIADMK---------DQLLKEKEDVETTKERINREKEHIEKMQS 13708
Query: 884 FRRDEIEDQNIKEE------IEKQIVETIYVTQIQELGEEHD---LLRLESAKYQDEIQS 1036
D+ E+ +++ + E Q+ +Q+L +E + L ++ K +++
Sbjct: 13709 QLNDQKEEMDLENQKLLYMKTEIQVKTNALEKMMQDLQKERENVNALVIQHQKEREQRDI 13768
Query: 1037 LKDECHAKEMSKQAEISKLSHTLE----------ESIMNSNLESLFTAEIYENTFRELGD 1186
L +E KE +AEI + +E I N E +E EN ++
Sbjct: 13769 LIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTRSEELENLIKKQQK 13828
Query: 1187 QISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEM 1366
+ N+M + ++ + + ++ S+E E+ LK +E
Sbjct: 13829 EFETKENEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILER 13888
Query: 1367 QCSKLKDELEEERGKISENLERISKLQK-MNNELAERSKSQNSIXXXXXXXXXXXXXXXX 1543
+ K EL +E+ ++ + + ++K M +E+ +N +
Sbjct: 13889 E----KSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELE--------------- 13929
Query: 1544 XXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQ 1723
+ + + ++++ IDK + E+ ++I + L K E E +
Sbjct: 13930 -----------DEKKSMLSRLSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKR 13978
Query: 1724 KVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVS 1903
L ++ IEK+ D L + SL L K + E +R K +Q +S
Sbjct: 13979 TQL---DNTIEKMNMDKL-SIQREKDSLEEIKADLQRKAEKLDEEMR---KAVQITSQIS 14031
Query: 1904 QEQHI---EHQCKEELEGHIADL-----------VLNDFSNDILSWSRRKEEAVVHDDEF 2041
Q+ I + + +EEL AD+ L +IL S+ + + + D E
Sbjct: 14032 QDAKILDDDREKEEELRSMRADIERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEK 14091
Query: 2042 DAERIAL-LNELKSLHQDLE-----LLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDG 2203
+R L L EL+ LE + K ++AV SL N V + + + E +
Sbjct: 14092 QRKRNDLTLQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRK- 14150
Query: 2204 EASDVQGKSRALRRHSTGQAFREPPKPEDLYTT-----YSEGKIVEPHPTEEKKLLA--I 2362
E D++ +R++ST + +E D++ ++ + ++ EE++ L I
Sbjct: 14151 EMDDLR-MQLEMRQNSTNKQQQE----VDVFIVENMKMRNDLESMKTLLDEERRQLQDNI 14205
Query: 2363 LAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNG 2542
FE P + +Q ++ +K E E ++++ EEI L + ++ K
Sbjct: 14206 KTFEDQKNVLHPSKTDAVQQ-TDELEKFTTDIKTEKE-HVEKEREEIDVLNKEIIKSKEE 14263
Query: 2543 LHAXXXXXXXXXXXXVAEITGKFEKV-----LQENKLLPVEE----VQRYKMLCVLKEEL 2695
L + EI GK ++ L+ + L ++ VQ K + + E
Sbjct: 14264 LQSLNLEIEMFK----QEIAGKRAQIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEK 14319
Query: 2696 QSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLL-KHIADLEAGITDREIM 2872
+++++ + K+K+ E+L + ++ + +L K ++E +IM
Sbjct: 14320 KTEVELQMNLQKQKNE-----LEELRNTIEAEKHQVENRKIMLDKQQKEVE------DIM 14368
Query: 2873 TSVCS--DVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLE----DKDKLLCLV 3034
T + S DVL +EK L+ E V ++Q L ++LE D + ++
Sbjct: 14369 TVIKSERDVLE-------KEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKII 14421
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLD----QALQECEELK 3202
E + +R+ A L++LKEE E R LQ +++ I+++K L+ + +E LK
Sbjct: 14422 ESEKQSIERERAELKRLKEEVEVQHERTLLQ-QDKNMIQKEKEHLEGEKARTTEEIHNLK 14480
Query: 3203 NDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLE-- 3376
+I+ K S++D L +E E ++ + + +++E
Sbjct: 14481 EEIKRKSSELDMLNKEIEAKRQE----------------------EELHGLPEEIEIEDH 14518
Query: 3377 LRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQ-------KAMEQKEAVLVEKLFE 3535
L+ ++ L+ EI KK D K + + R A TQ K E+++ L E +
Sbjct: 14519 LKKEDDVLREEIIKKQ-QTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRALEETVAT 14577
Query: 3536 GEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTE 3715
++ ++++ + T E ++ RD LN+ +E A +K ++L+ + D++ M E
Sbjct: 14578 TAKQPIVIKLEDTLTSE-VQEMRDHLNNEIKELARMKTIMKMEKDQLKQAKSDIQTQMEE 14636
Query: 3716 TKFLKEKLLVSDENLKEKDLQL 3781
+ E+ + +EK LQL
Sbjct: 14637 FERNMEEAMEEKSRNEEKLLQL 14658
Score = 108 bits (270), Expect = 2e-20
Identities = 257/1319 (19%), Positives = 522/1319 (39%), Gaps = 140/1319 (10%)
Frame = +2
Query: 230 VMDGQGCDISVTSFIEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNF----- 394
+ D Q I S ++ E+ + + K ETL+ ME H +K+++
Sbjct: 11110 IADEQDLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRL 11169
Query: 395 --DLGQDNPGVPGLLEDIRNTKDLLDTVESGL-----YVSNVVSDAVLNGVVSAQ-EEEF 550
DL + + V +D+ N +DLL+ + + + + + VS Q E++
Sbjct: 11170 KEDLEKMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQQRIDE--FDAQVSKQKEQDL 11227
Query: 551 KEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEK 730
+ K+ L K + K + E ++ ++E E E R++ + K
Sbjct: 11228 PKEKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVE-TERK 11286
Query: 731 DLMQQRAQ--------ETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCF 886
+L Q +++ + EQK + N+ M M+ ++ + + +I Q Q +
Sbjct: 11287 ELYQIKSELERVRSEIDHEQK---KLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSE 11343
Query: 887 RRDEIEDQNI-KEEIEK--QIVETIYVT-----------------QIQELGEEHDLLRLE 1006
++I+ N+ K +IEK +IVE + V + Q++ +E +LL
Sbjct: 11344 LDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQN 11403
Query: 1007 SAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGD 1186
AK Q+E + +K EI K TL E ++ E I E T R D
Sbjct: 11404 KAKLQNENERIK--------KVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKED 11455
Query: 1187 QISQLRNDMYSKNSYI----DSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKA 1354
+ ++ D+ + ++ D L + ++ E +LQ++ A
Sbjct: 11456 -LEKMSTDINEQKLHLKNQRDLLEQEREEINHEMTQLQQRIDE--------------FDA 11500
Query: 1355 SMEMQCSKL-KDELEEERGKISENLERI------SKLQKMNNELAERSKSQNSIXXXXXX 1513
+ Q L K E+EEER + E RI ++LQ++ E E + + +
Sbjct: 11501 QVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRV------ 11554
Query: 1514 XXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLS 1693
+V M +L ++ ++ S ID ++ +++ I + L
Sbjct: 11555 --------------IVEME-REELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLE 11599
Query: 1694 NQKFEIEKSQKVLQSFESHIEKLVNDS---LHEVDSAFCSLNSRFYSLIHKVDNSGETLR 1864
K EI ++ ++ S ++ + + H+++++ L+ KV+ + +R
Sbjct: 11600 KMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENS----KEIVQKLMVKVEEQRKDIR 11655
Query: 1865 AFVKNIQ-NQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEF 2041
+ + + ++ EQ + Q K +L+ N+ ++ ++++E + E
Sbjct: 11656 LQKEELDIERQKIADEQGLVVQNKAKLQNE------NERIKEMDEEIKKEKETL---KEM 11706
Query: 2042 DAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQ 2221
+A E++S+ ++ + K E+ ++ +S +V + + L+++ E ++
Sbjct: 11707 EAHLRKEKEEMRSVIEETQRRKKED-LEKMSTDVNKQNQDLMNQRDLLKQ----EREEIN 11761
Query: 2222 GK-SRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSP 2398
K ++ +R A K EDL + K+ E + E+ + I+ +T +
Sbjct: 11762 HKWTQLQQRIDEFDAQVSKQKEEDL---TKQKKMEEERKSLEETKIKIIEMKTKTEPEKI 11818
Query: 2399 LRNWPKEQ------LLGHFKQSFAGLKREYE---LELQRKTEEIYDLKRLLLNEKNGLHA 2551
+ KE+ + K+ +K + E E+ + +++ D K+++ EK L
Sbjct: 11819 KKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEK 11878
Query: 2552 XXXXXXXXXXXXVAEITGKFEKVLQEN-------------KLLPVEEVQRYKMLCVLKEE 2692
E + K+ Q + + L VE ++ K + + KEE
Sbjct: 11879 MKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEE 11938
Query: 2693 L-----------------QSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHL 2821
L ++K+ + + IKE D K K + LK+ H ++E
Sbjct: 11939 LDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHLRKEKEE 11994
Query: 2822 LKHI---------ADLEAGITD-----------REIMTSVCSDVLTALFVEMVREKEFSL 2941
++ + DLE TD R+++ ++ R EF
Sbjct: 11995 MRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDA 12054
Query: 2942 SLA-TKEQETVNQKQM-SLRKMLED-KDKLLCLVGEENKEHKRQIAILEKLKEETENNPG 3112
++ KE++ QK+M RK LE+ K K++ + + E ++ EK KEE E
Sbjct: 12055 QVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKK----EKEKEEEEVMRA 12110
Query: 3113 RVFLQSEE-----------REKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEK 3259
+V ++ EE R +I+ +++ L+ + E+ K D++ S+I R++ E+
Sbjct: 12111 KVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEE 12170
Query: 3260 LNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDL 3439
+L + ++ + E++ EEL E +K + + DL
Sbjct: 12171 ERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDL 12230
Query: 3440 LIKEKEEL---NERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDL 3610
LI+ K EL NER+ + ++++ L E E++ ++S TR Q E +
Sbjct: 12231 LIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSITEETRRQKEDLEKM 12290
Query: 3611 LNSLTEEHADLKKQ---FLSATEELQSKERDLEVAMTE----TKFLKEKLLVSDENLKE 3766
+ E+ DL+ Q EE+ K + L+ + E KE+ L ++ +KE
Sbjct: 12291 STHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKE 12349
Score = 107 bits (266), Expect = 5e-20
Identities = 223/1154 (19%), Positives = 456/1154 (39%), Gaps = 85/1154 (7%)
Frame = +2
Query: 596 KKIEDLNHKIWSLEETLQYKEEVILSSHETIS-ERDRLLKDFIHEKDLMQQ-RAQETEQK 769
K IE +I E L+ ++ + S +T+ ER L K KDL +Q +Q + +
Sbjct: 2854 KDIETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHE 2913
Query: 770 LASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIV-E 946
+ + + +LE+ + LS K+ +L+ + DCF +++ D +++EE+++Q E
Sbjct: 2914 IQLAEIQKEREILEQLKLTLSKQKE-DLEKER----DCFEKEKA-DISLREELQEQSERE 2967
Query: 947 TIYVTQIQELGEEHDLLR--------LESAKYQDEI---QSLKDECHAKEMSKQAEISKL 1093
I T+++ E +L + LE+ + Q +I + K E E+ K+AE ++
Sbjct: 2968 GIGKTRVRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEK 3027
Query: 1094 SHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSE 1273
E +N E + + N +++ ++R++ + L S D L E
Sbjct: 3028 QRRDIEKDRRNNEEMVIKLQ---NEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKE 3084
Query: 1274 -------------CNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERG-- 1408
K E + +++ SK K++LE+ER
Sbjct: 3085 RFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCF 3144
Query: 1409 -------KISENLERISKLQKMNN-------ELAERSKSQNSIXXXXXXXXXXXXXXXXX 1546
+SE+L+ S+ + ++N E+ E K++ ++
Sbjct: 3145 EKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDE 3204
Query: 1547 XXXVVNM-------AFGSKLEELTDQINI--FNSVIDKKEAEVSGHLDTISSLQTVLSNQ 1699
+ + A +KLE ++ N+ + + K V + + Q VL N
Sbjct: 3205 RDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKKDRENVESLAEELGRKQVVLENM 3264
Query: 1700 KFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKN 1879
+ E E +K +S + E+++ + V + K D + L KN
Sbjct: 3265 QIETEMQRKANESNKQMQERVLIELKKTVTDIAGA----------KEDLENQLLEEREKN 3314
Query: 1880 IQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVH--DDEFDAER 2053
Q + E+ + + K+ + D+V + + +A+++ DE +A R
Sbjct: 3315 KVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQLRLREVELEQLQALIYRQQDEIEANR 3374
Query: 2054 IALLNELKSLH-QDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKS 2230
A++NE L Q E+ + + V + + Y S KD + +
Sbjct: 3375 KAIINEKYRLEGQKTEIDRLQREVNQM----------MEYAS------KDRANLEKEKSE 3418
Query: 2231 RALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNW 2410
++H D+ G I EE+ + + D + L
Sbjct: 3419 MIAQKHQM-----------DIELNKERGLI------EERTQMLNTYEKEMDQKRTALEVE 3461
Query: 2411 PKEQLLGHFKQSFAGLK---REYELELQRKTEEIYDLKRLLLNEKNGLH--AXXXXXXXX 2575
KE L + KQ+ K ++ ++ELQR+ ++I LK NE+ L A
Sbjct: 3462 MKE--LKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKD 3519
Query: 2576 XXXXVAEITGKFE---KVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSN 2746
+AE T + + KVL E+ L +++ K L+ +S+ K+ + DS
Sbjct: 3520 DLAHLAEDTKRKDDEMKVLHESALADIQKE---------KCNLEQMRESMFKQNEMIDSE 3570
Query: 2747 SK--VLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMV 2920
K +L E ++ + Q E K I + +R MT D++T L +
Sbjct: 3571 KKKMILREDKLQQMQAEINRQQTEMDTKKSIIE-----NERAAMTKKNQDLMTEL-TKQS 3624
Query: 2921 REKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETE 3100
+ E + E+E + + L+K +E+ + L ++ ++ E LK++ E
Sbjct: 3625 EDVEIQMKEVLTEKELLESDRKLLKKDVENLQQKLLIIESDS----------ESLKQDRE 3674
Query: 3101 NNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRC 3280
L E+E +++ K L +E E++K + Q++ ++ + + +K + L+
Sbjct: 3675 -------LLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQK 3727
Query: 3281 MXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEEL-----------------KNE 3409
M LD ++ E++N +EL ++E
Sbjct: 3728 MNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLKQSE 3787
Query: 3410 IEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQ 3589
++K+ T+++ +I+ + ++L ++ ME+++ + ++ + +Q L+ + Q
Sbjct: 3788 LDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQ 3847
Query: 3590 TEKYRDLLNSLTEEHADLKK---QFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENL 3760
+ + + N L + +L++ + EE+Q++ + LE E K KE E+
Sbjct: 3848 KQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESFTHLAEDT 3907
Query: 3761 KEKDLQLRAFEIAN 3802
K++ L ++AN
Sbjct: 3908 KKEQEILDEIKVAN 3921
Score = 107 bits (266), Expect = 5e-20
Identities = 244/1167 (20%), Positives = 478/1167 (40%), Gaps = 76/1167 (6%)
Frame = +2
Query: 536 QEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKD 715
QE + +A K E ++ +KIE E +Q +++ + S E + ++ + +K
Sbjct: 8171 QELDLIQAKVVKQKEE-MVKQKIES--------EREIQQEKKKLQRSEEELEDKMQKIKR 8221
Query: 716 FIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNI------ILSLHKQIELQSQNTQSL 877
+ E L+Q ET+ K DN+M + ++D + + S K++E+ +
Sbjct: 8222 EMIELKLLQD---ETDGKRKDVDNKMRQVARKRDELEKMKADVESASKKLEVDRVMLNT- 8277
Query: 878 DCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDL------LRLESAKYQDEIQSL 1039
RDE+E + + + +++ + +LGE+ + L E+ K S
Sbjct: 8278 ---ERDELERIKTESQRATEHMQSHAEERAGDLGEKEPVNTRIQRLIQEAEKASKMAWST 8334
Query: 1040 KDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTA-EIYENTFRELGDQISQLRNDMY 1216
K H EM Q E+S ++E M++N++ + E T R + D++ R +
Sbjct: 8335 K---HEPEMRMQREVSVEEESVERQDMSANMQRMILEIEHARETLRGMKDEVQAARKE-- 8389
Query: 1217 SKNSYIDSLASRIDFLSSECN--KLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDE 1390
S ++++ +++FL+ + N K EQ S +M S+ +++
Sbjct: 8390 --RSELENM--KLEFLTMKKNMEKTYEQQNDEIQKEKQQIE-------SSKMLLSRERND 8438
Query: 1391 LEEERGKISENLERISKLQKMN----NELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXV 1558
LE+ R + E ++I L K NEL ER K+ +
Sbjct: 8439 LEQNRADL-ERQKQIMALDKQKLLAENELLEREKAD--VIKIIENLESLREEATRERATE 8495
Query: 1559 VNMAFGSKLEELTDQINIFNSVIDKKEA------EVSGHLDTISSLQTVLSNQKFEIEKS 1720
A EEL ++ S+ D +EA E+ +D + L+ L Q+ E++K+
Sbjct: 8496 TAQATRRDSEELMQKMEAL-SMEDFQEASKNQMVELKRQIDKLIELKADLLQQQTELKKT 8554
Query: 1721 QKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAV 1900
+ L+ +EK +R L H+ D +T + IQ Q
Sbjct: 8555 KADLKQQMDDLEK-----------------TRSEILKHEKDTDSKTRELELIEIQRQ--- 8594
Query: 1901 SQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALL---NE 2071
K++LE I L L ++L + E V+ + D + ++ +E
Sbjct: 8595 ----------KDDLETRIQKLTLEKRDLEVL-----RSEIVLEKKDLDQKMKQVIRKRDE 8639
Query: 2072 LKSLHQDL-----ELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQ-----EGKDGEASDVQ 2221
++ + D+ E+ + + ++ L NNV + H F L++ E ++ A+D++
Sbjct: 8640 MEKIRSDIANATEEINRERQELEILRNNVQSAR---HDFELLLERTANLEDEESAATDIE 8696
Query: 2222 G------KSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETAD 2383
K R + R+ G+ R K + VE +EK++
Sbjct: 8697 RLVLEVVKIREMVRNLKGEMERRMEKSK-----------VE---IDEKEIFK-------- 8734
Query: 2384 ASDSPLRNWPKEQLLGHFKQSFAGL----------KREYE---LELQRKTEEIYDLKRLL 2524
S ++ + ++ +G +++ GL KRE E EL K +E ++ +L
Sbjct: 8735 ---SEIQRFIQD--IGQIRENLGGLGEEIEKTRRDKRELEKMRAELAEKQQEQESMREML 8789
Query: 2525 LNEKNGLHAXXXXXXXXXXXXVAEITGKF-EKVLQENKLLPVEEVQRYKMLCVLKEELQS 2701
E+ L EI + E V+ + ++ ++Q+YK EELQS
Sbjct: 8790 HKEREELEQLKDEINREKED--VEIRRELVEAVIDKEEMKEFTDIQKYK------EELQS 8841
Query: 2702 KIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSV 2881
+ LL + ++ D + + + + + H ++ + L +L+ G E +
Sbjct: 8842 VTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFELKKG----EQLLEK 8897
Query: 2882 CSDVL--TALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEH 3055
D L VE ++ K+ SL E +N M + + ED DK + +E +E
Sbjct: 8898 QKDELKENGWIVEEIKNKKDSL-------EKIN---MEILRKNEDMDKEKGKLRQEKQEM 8947
Query: 3056 KRQIAILEKLKEETENNPGRVFLQSEE----REKIEEQKRVLDQALQ-------ECEELK 3202
+ L++ +E+ E + ++ + E R +I +K+ LDQ ++ E E+++
Sbjct: 8948 DLFRSELQRQREDLETSIQKLTHEKREMEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIR 9007
Query: 3203 NDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELR 3382
DI N +ID R+E E L ++ S+ D +L R
Sbjct: 9008 FDIANARVEIDGERQELEILRDNVQ-----------------------SARQDFERLVER 9044
Query: 3383 NYNEELKNEIEKKSTDIDLLIKEKEELNERL----AYTQKAMEQKEAVLVEK-LFEGEQK 3547
N E++ E +TDI+ L+ E ++ E + ++ ME+ + + EK +F+ E +
Sbjct: 9045 TANLEVE---ESAATDIERLVLEVVKIREMVRNLKGEMERRMEESKVEIDEKEIFKSEIQ 9101
Query: 3548 ILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFL 3727
L+ + Q RE + + + + ++L+K E+ Q +E E+ E + L
Sbjct: 9102 RLIQDIGQ--IRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQEEESMREILQKEKEEL 9159
Query: 3728 KEKLLVSDENLKEKDLQLRAFEIANSE 3808
++ L D N +++D+++ + E+ SE
Sbjct: 9160 EQ--LKKDINREKEDIEI-SRELVESE 9183
Score = 106 bits (265), Expect = 7e-20
Identities = 223/1183 (18%), Positives = 477/1183 (40%), Gaps = 92/1183 (7%)
Frame = +2
Query: 536 QEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKD 715
+EE + + K E + ++E + +I ++ L +++I E + +++ +
Sbjct: 11826 EEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDL---EKMKSE 11882
Query: 716 FIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNT----QSLDC 883
+ ++ M++ E + K+ D E H + I+ L ++E Q ++ + LD
Sbjct: 11883 IMKQRQQMEEERSELDNKIKQTDLER-HDIENSKEIVQKLMVEVEEQRKDIRLQKEELDI 11941
Query: 884 FRRDEIEDQNIKEEIEKQIV-ETIYVTQI-QELGEEHDLLRLESAKYQDEIQSLKDECHA 1057
R+ ++Q + + + ++ E + ++ +E+ +E + L+ A + E + ++
Sbjct: 11942 ERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEE 12001
Query: 1058 KEMSKQAEISKLSHTLEESIMN-SNLESLFTAEIYENTFR---------ELGDQISQLRN 1207
+ ++ ++ K+S + + + N L E E + E Q+S+ +
Sbjct: 12002 TQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKE 12061
Query: 1208 DMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEM------- 1366
+ +K ++ ++ + +++ + ++A +EM
Sbjct: 12062 EDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQ 12121
Query: 1367 ---QCSKLKDELEEERGKISENLERISK----LQKMNNELA--------ERSKSQNSIXX 1501
Q +++ E++ E+ K++++ + I + L+KM +E+ ERS+ +N I
Sbjct: 12122 IKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQ 12181
Query: 1502 XXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQ 1681
+V ++EE +I +D + +++ D + +
Sbjct: 12182 TYIEKCDIENSKEIVQKLMV------EVEEQKHEIQFQKEELDIERQKIADEQDLLIQNK 12235
Query: 1682 TVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETL 1861
+ L N+ I+ +V+ K ++L E+++ S+ + E L
Sbjct: 12236 SELQNENERIKNINEVI--------KKERETLKEMEAYLEKEKEEMKSITEETRRQKEDL 12287
Query: 1862 RAFVKNI--QNQVAVSQEQHIEHQCKEELEGHIADLV--LNDFSNDILSWSRRKEEAVVH 2029
+I Q Q SQ +E + +EE+ L +++F + S++KEE +
Sbjct: 12288 EKMSTHINEQKQDLRSQRDLLEQE-REEINHKWKQLQQRIDEFDAQV---SKQKEEDLPK 12343
Query: 2030 DDEFDAERIAL------LNELKSLHQDLELLKA---EEAVKSLSNNVGVSTKGIHYF-SQ 2179
+ E +R +L + E+K+ + E+ K EE + + V + K I SQ
Sbjct: 12344 EKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQ 12403
Query: 2180 L--IQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKL 2353
L ++ D E + + + + EDL SE EE+
Sbjct: 12404 LERVRSEMDHEQKKLNDDKKMIEQEK-----------EDLEKMKSEIMKQRQQMEEERSE 12452
Query: 2354 LAILAFETADASDSPLRNWPK--EQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLL 2527
L +T D + N + E+L+ + K+++E++ Q+ E D++R +
Sbjct: 12453 LDKKIKQT-DLEKHDIENSKEIVEKLMVEVE------KQKHEIQFQK---EELDIERQKI 12502
Query: 2528 NEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKI 2707
++ L + E+ E++ +E + L EV K KEE++S I
Sbjct: 12503 ADEQDLLIQNKIEQQNENERIKEMD---EEIKKERETLKEMEVNLQKE----KEEIESVI 12555
Query: 2708 DSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCS 2887
+ + ++ + S + E+ D + + Q + + L+ I + E S
Sbjct: 12556 EETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFE----TTS 12611
Query: 2888 DVLTALFVEMVREKEFSLSLATKEQETV----NQKQMSLRKMLEDKDKLLCLVGEENKEH 3055
++L +E E + L A KE E++ N+K+ L ++ D+ ++NK
Sbjct: 12612 NILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTELEEIEVDQS-------QQNKNV 12664
Query: 3056 KRQIAILEKLKEETENNPGRVFLQSEERE--------KIEEQKRVLDQALQECEELKNDI 3211
+ +LEK +++TE + Q+++ E K E KR LD+ + E+ N+I
Sbjct: 12665 ETMKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEI 12724
Query: 3212 QNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYN 3391
+ D++ +E+++ + K + LD +Q E++N
Sbjct: 12725 LRQRDDLE--KEKEDMMKKW--------------------------NELDGLQKEIQNQK 12756
Query: 3392 ---EELKNEIEKKSTDIDLLIKEKEELNERLAYT--------------QKAMEQKEAVLV 3520
EE+K E+E K +I IKE++ L E L +K +Q E + V
Sbjct: 12757 NEMEEIKCELETKRIEI---IKEQKRLEESLNTVNEERQYLEIVRVDYEKHQQQIEEMRV 12813
Query: 3521 EKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEEL-------Q 3679
+ E ++ L+ + R++ E+ +D++ L +E K + EEL Q
Sbjct: 12814 KTKMERDELDQLM-AKMLMDRKENERSKDMIGLLKKEMEQTKFNLDAQEEELKLEKQKIQ 12872
Query: 3680 SKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSE 3808
++++DLE+ E K ++ E EKD +AFE E
Sbjct: 12873 NEKKDLEMFKAEIKREASEVKTLKEQQLEKD--TKAFEALKEE 12913
Score = 105 bits (263), Expect = 1e-19
Identities = 245/1365 (17%), Positives = 518/1365 (37%), Gaps = 201/1365 (14%)
Frame = +2
Query: 320 KIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGLYVSNV 499
K E L+++++ L+ +L + + ED+ N K+ L E L+
Sbjct: 6322 KEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLREDELWQ--- 6378
Query: 500 VSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLE---ETLQYKEEVIL 670
L + Q+ E ++ +SE + K +EDL HKI SL+ E+L+ E
Sbjct: 6379 -----LQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFE 6433
Query: 671 SSHETISERDRLLKDFIHEKDLMQQRAQETEQKLAS------RDNEMMHMVLE----KDN 820
+ E + + L+ E + ++ Q Q++ +D + ++ ++E KD
Sbjct: 6434 NEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDM 6493
Query: 821 IILSLHKQIELQSQNTQSLDCFRRDEIED--------QNIKEEIEKQIVETIYVTQIQEL 976
++ ++ IE + ++ QS E D +KE++EKQ T+ QIQ+
Sbjct: 6494 VLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTL--AQIQKE 6551
Query: 977 GEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEI 1156
E+ + + + EI+ +++ + KQ E+ +L + I N E EI
Sbjct: 6552 REDLEKMNENITREMHEIKHQEEQMN----QKQDELDQL----KTEIQNLQQELEKEKEI 6603
Query: 1157 YENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXX 1336
+L + S+L + N ++++ + L + +++EQ
Sbjct: 6604 IMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQS 6663
Query: 1337 XXTLKASMEM-------------QCSKLKDELEEERGKISENLERISKLQKMNNELAERS 1477
+L ++M + ++K ELE E I + E +++ ++AE
Sbjct: 6664 RKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEEL 6723
Query: 1478 KSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGH 1657
K + V N + + L++ + I K+ ++
Sbjct: 6724 KKERK-DVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKE 6782
Query: 1658 LDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEK----LVNDSLHEVDSAFCSLNSRFYS 1825
D I + L + EI K Q + +S+IE+ ++ D + ++ S SL+ S
Sbjct: 6783 KDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKD-VEDLQSKIISLDRDAES 6841
Query: 1826 LI---HKVDNSGETLRAFVKNIQNQV----AVSQEQHIEHQCKEELEGHIADLVLND--- 1975
L +N E L+ ++ + + E E Q EE+ + + N+
Sbjct: 6842 LKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQ 6901
Query: 1976 FSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAE-------------- 2113
+ + +K+E D+ D R +L +LK + ++L+ E
Sbjct: 6902 LDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLERE 6961
Query: 2114 -EAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTG----------- 2257
+ + + + + + ++E ++ A +++ K++ L +
Sbjct: 6962 ADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLADLQKE 7021
Query: 2258 ----QAFRE--PPKPEDLYTTYSEGKIVEPH----PTEEKKLLAILAFETADA-SDSPLR 2404
+ RE + ED+ + K+ E TE +K + + E + S+
Sbjct: 7022 KRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAAM 7081
Query: 2405 NWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXX 2584
K+ ++ K K+ ++E+Q K EI K LL N++N L
Sbjct: 7082 IREKQNMMTELK------KKSEDVEMQMK--EILTEKELLHNDRNLLKKDVEDLQQKLMS 7133
Query: 2585 XVAEITG-KFEKVLQEN----------------------KLLPVEEVQRYKMLCVLKEEL 2695
+ K +K EN KL E QR + ++
Sbjct: 7134 IERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKE 7193
Query: 2696 QSKIDSLLKEIKEK-----DSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITD 2860
+ +I++L++EIK+K +S +++ EK + +S D + +S K ++E + +
Sbjct: 7194 REEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRS-DLEKAKSQTFKQNKNIEIALAE 7252
Query: 2861 REIMTSVCSDVLTALFVEMVR--EKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLV 3034
+ + + + + ++ +++ + LA +E E ++ +++ E KD LL +
Sbjct: 7253 IQQKRNALEKMSKEISRDRMKLEDEKKEIQLAREELERMHG---DMQRQQEAKDHLLSGI 7309
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGR-----------VFLQS----------------- 3130
+E+ K + I+ + + + P R VF+Q
Sbjct: 7310 TDESLLKKSEAEIVLQPSQVDKAKPARKTEISDSDKQPVFVQQMPEMDLKDALKKDFESE 7369
Query: 3131 -------------------------EEREKIEEQKRVLDQALQECEELKNDIQNKHSDID 3235
+E +K+++ + L + + E+ K D+QN+ +D
Sbjct: 7370 KLDLPKVKDVLPQDQQMKLEQKLIEDEMDKLKQMRAELQKEADQIEKKKQDMQNERQKLD 7429
Query: 3236 SL-------REEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNE 3394
+ R E+LN+++ ++ + ++ E+ N+
Sbjct: 7430 DMAARLQEERRTNERLNEEINIQKVNQQKQATAFQME-------KTDFERIKTEIDQANK 7482
Query: 3395 ELKNEIEKKSTDIDLLIKEKEELNERLAYTQK-------------AMEQKEAVLVEKLFE 3535
EL ++ EK I + KE+E L E A K + E + A L E + +
Sbjct: 7483 ELADQQEKNKKTITEMQKERETLEEMRANISKQVETITNENKSLSSRESELAKLQEDILQ 7542
Query: 3536 GEQKILLLESS---QSATREQTEKYRDLLNSLTEEHADLKKQFLSATE----ELQSKERD 3694
+Q++ L+++ + +Q + DLL ++ D K ++ E E+ ++ R+
Sbjct: 7543 QQQEMDELKNTIMMEMCQLDQRQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQTRN 7602
Query: 3695 LEVAMTETKFLKEKL------LVSDENLKEKDLQLRAFEIANSEK 3811
++ M K KE L +++L EK+ +L + +++K
Sbjct: 7603 IKSDMVSLKMEKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDK 7647
Score = 104 bits (259), Expect = 3e-19
Identities = 222/1208 (18%), Positives = 484/1208 (40%), Gaps = 43/1208 (3%)
Frame = +2
Query: 326 AETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGLYVSNVVS 505
+E + ME + TLK L +D + ++E+ K+ L+ + +G+ V
Sbjct: 10559 SEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNV----- 10613
Query: 506 DAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHET 685
Q++E K + E +N K +I + ++ ++E L++ +
Sbjct: 10614 ----------QKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEEDLTNQKK 10663
Query: 686 ISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQN 865
+ E + L++ ++ K + + E E H + +K + +L +QI + +
Sbjct: 10664 MEEERKCLEE-VNGKIIEMKTKAELEH----------HEINQKIEELQTLQEQIMKEKEK 10712
Query: 866 TQSLDCFRRDEIED-QNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLK 1042
+++ + E ED IK E+ ++ E + + ++L ++ ++ E +++++ +K
Sbjct: 10713 AEAMTIKLKMEREDLDQIKSELVREKTEVDH--EQKKLNDDIKMIEQE----KEDLEKMK 10766
Query: 1043 DECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSK 1222
E ++ + E S+L + ++++ + + + + EI E E+ +Q +++
Sbjct: 10767 SEIMTQKQEMEKERSELDNKIQQTDLEKH-DIEKSKEIVEKLMFEVEEQRHEIQLQKEEL 10825
Query: 1223 NSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELE-- 1396
+ +A D L ++LQ + TLK ME K K+E++
Sbjct: 10826 DIERQKIADEQDLLIQNKSELQNENERIRNINEVIKKERETLK-EMEAHLEKEKEEMKSI 10884
Query: 1397 -EERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAF 1573
EE + E+LE++S K N+ + K ++ +
Sbjct: 10885 TEETRRQKEDLEKMSTDIKEQNQ--DLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQVS 10942
Query: 1574 GSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHI 1753
K E+LT Q + ++K E +T + + + + + E K +K + E +
Sbjct: 10943 KQKEEDLTKQKEMKE---ERKSLE-----ETKARIIEMKTKAELEDIKKEKEKEEEEEEM 10994
Query: 1754 EKLVNDSLHEVDSAFCSLNSRFYSLIH---KVDNSGETLRAFVKNIQNQVA--VSQEQHI 1918
V E+D L + H K+++ + + +N++ + + Q Q +
Sbjct: 10995 RVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKSEIMKQRQQM 11054
Query: 1919 EHQCKEELEGHIADLVLN--DFSND-------ILSWSRRKEEAVVHDDEFDAERIALLNE 2071
E + + ELE I + D N ++ +K E +E D ER + +E
Sbjct: 11055 EEE-RSELENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADE 11113
Query: 2072 LKSLHQDL-ELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRH 2248
L Q+ EL E +++L+ + + + +++ K+ E V ++R L+
Sbjct: 11114 QDLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKE-EIKSVSEETRRLKED 11172
Query: 2249 STGQAFREPPKPEDLYTTYSEGKIVEPHPTEE----KKLLAILAFETADASDSPLRNWPK 2416
+ + +DL ++ ++E E K+L + A S ++ PK
Sbjct: 11173 LEKMSTDVNKQNKDLM---NQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPK 11229
Query: 2417 EQLLGHFKQSFAGLKREY-ELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVA 2593
E+ + ++S K E++ + + EEI K E+ +
Sbjct: 11230 EKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELY 11289
Query: 2594 EITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLS 2773
+I + E+V E + KM+ KE+L+ ++K+ ++ + L K+
Sbjct: 11290 QIKSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKI- 11348
Query: 2774 DALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLAT 2953
++++L KH D+E +++ L VE V E+ + L
Sbjct: 11349 -----------QQTNLEKH--DIEKS-----------KEIVEKLMVE-VEEQRKDIQLQK 11383
Query: 2954 KEQETVNQKQMSLRKML-EDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQS 3130
+E + QK + +L ++K KL E++R + E++K+E E
Sbjct: 11384 EELDIERQKIADEQNLLVQNKAKL-------QNENERIKKVDEEIKKERET-------LR 11429
Query: 3131 EEREKIEEQKRVLDQALQECEELKNDIQNKHSDI-----------DSLREEQEKLNKQLR 3277
E ++++K L ++E + K D++ +DI D L +E+E++N ++
Sbjct: 11430 EMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREEINHEMT 11489
Query: 3278 CMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEEL-KNEIEKKSTDID------ 3436
+ +D ++ E+L K E+E++ ++
Sbjct: 11490 ---------------------QLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARI 11528
Query: 3437 LLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLN 3616
+ +K K EL E + ++ E++ V+VE +++ ++S R + + + LN
Sbjct: 11529 IEMKTKAELQEIMQEKEEEDEEEMRVIVEM---EREELNQIKSELKRVRSEIDHEQKKLN 11585
Query: 3617 SLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEI 3796
D KK E+L+ + ++ MT+ + ++E+ D +K+ DL+ +I
Sbjct: 11586 -------DDKKIIEQEKEDLEKMKSEI---MTQRQQMEEERSELDNKIKQTDLE--RHDI 11633
Query: 3797 ANSEKQYQ 3820
NS++ Q
Sbjct: 11634 ENSKEIVQ 11641
Score = 102 bits (255), Expect = 1e-18
Identities = 220/1188 (18%), Positives = 496/1188 (41%), Gaps = 26/1188 (2%)
Frame = +2
Query: 296 DTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVE 475
D +S+ +AE E++ I L++ +L ++ + + E+ + ++ +D +
Sbjct: 2071 DKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIR 2130
Query: 476 SGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYK 655
G+ + + + + ++ A +++ + K I+++ +++ QY
Sbjct: 2131 VGIEKQEITFKDL--------KADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQKERQYM 2182
Query: 656 EEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLAS--RDNEMMHMVLEKDNIIL 829
+ ++ + D + + E+ ++ + E EQ+ + D + EK+NII
Sbjct: 2183 DRLVEEIEKRTKALDEMQMEVDKERQEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQ 2242
Query: 830 SLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLES 1009
+ +I+ +S N E++ +NI +E TI+ EL +EH LR
Sbjct: 2243 A---EIQKESDNL---------ELQSENISKE------RTIF-----ELEKEHLGLRENE 2279
Query: 1010 AKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQ 1189
A+Y+ Q DE K ++ ++ ++ ++ E + TA E T
Sbjct: 2280 AEYK---QKQIDELQNKLRMEKVQVEQMQ--ADKDQQRKKAEYVKTARGRETT------A 2328
Query: 1190 ISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQ 1369
+ + R +M +SL + + + + EQ +K E +
Sbjct: 2329 LEEQRQEM-------ESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKYKE-K 2380
Query: 1370 CSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXX 1549
K ++L+ +R + ++++ ++ E ER K + I
Sbjct: 2381 LDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEI---QKPAVYTETYMLETQ 2437
Query: 1550 XXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKV 1729
VV + +L+E+ +IN S ++K+++ + IS ++ + EK +
Sbjct: 2438 KPVVEKSKTDELDEVRKKINADLSEVEKQKSALVQMNLKISQEESYVKK-----EKDRLK 2492
Query: 1730 LQSFESHIE-KLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQ 1906
LQ E +++ +N +E+D + + L + +D + + +V +++
Sbjct: 2493 LQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMD----------RLEKEKVEITK 2542
Query: 1907 EQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLH 2086
E+ ++ + E++ A S D++ K+E + D + R L EL+ +
Sbjct: 2543 EKQRVNEMQNEVKRKNA-------SVDLI-----KQEVLREQDHIENSREILNRELEKIK 2590
Query: 2087 QDLELLKAE-EAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRAL---RRHST 2254
+ +L E EA+ +G + + +Q+ EA D + + R + RR++
Sbjct: 2591 EKKTILAEEFEALDDKKEMIGKEMQRLGKMKAELQK----EAEDTEKQRRDIDNDRRNNE 2646
Query: 2255 GQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGH 2434
+ + +D+ T+ + E + +K+ L +T + L E +
Sbjct: 2647 EMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLE-SDRDTLEKERFDLEKTKTE--MKD 2703
Query: 2435 FKQSFAGLKREYEL---ELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITG 2605
++ R++E+ E+Q++ E + LK L +K L A+I+
Sbjct: 2704 LEKQLESQSRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEK----ADISL 2759
Query: 2606 KFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSN--SKVLAEKLSDA 2779
+ E Q K E + + ++ +K+E+ + L +KE ++N K + E D
Sbjct: 2760 REELEEQSEK----EGIDKTRVR--IKQEMDELEQTRLNVVKELENNELQKQIIEDERDK 2813
Query: 2780 LKKSADHAQRES-HLLKHIADLEAGITDREIMT----SVCSDVLTALFVEMVREKEFSLS 2944
+++ Q+E+ K D+E + E M + D+ T+ + +R++E +L
Sbjct: 2814 IEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETS--TDRIRDEEANLR 2871
Query: 2945 LATK----EQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPG 3112
+ + +++T+ +++ L+K + L + +N++H+ Q+A ++K
Sbjct: 2872 VLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQK---------- 2921
Query: 3113 RVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXX 3292
ERE +E+ K L + ++ E+ ++ + + +DI SLREE ++ +++
Sbjct: 2922 -------EREILEQLKLTLSKQKEDLEKERDCFEKEKADI-SLREELQEQSER------- 2966
Query: 3293 XXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELK-NEIEKKSTDIDLLIKEKEELNE 3469
I +D ++ N +EL+ NE++K+ ++ E++++ +
Sbjct: 2967 --------EGIGKTRVRIKKEMDELKQTRLNVVKELENNELQKQ-----IIEDERDKIEQ 3013
Query: 3470 RLAYTQKAME--QKEAVLVEK-LFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHAD 3640
A QK E +K+ +EK E+ ++ L++ + T++ RD E + +
Sbjct: 3014 IKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETSTDRIRD-----EEANLE 3068
Query: 3641 LKKQFLSATEELQSKER-DLEVAMTETKFLKEKLLVSDENLKEKDLQL 3781
++KQ L + + KER DLE TE LK++L + +++ ++QL
Sbjct: 3069 VQKQRLESDRDTLEKERFDLEKTKTEMGNLKKQL---ESQIRQHEIQL 3113
Score = 101 bits (252), Expect = 2e-18
Identities = 227/1221 (18%), Positives = 499/1221 (40%), Gaps = 47/1221 (3%)
Frame = +2
Query: 257 SVTSFIEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLE 436
SVT + + LD S + +T+E + I G L+ + F+L + LLE
Sbjct: 8841 SVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFELKKGEQ----LLE 8896
Query: 437 DIRNTKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLN 616
KD L E+G V EE K + + N + +K ED++
Sbjct: 8897 ---KQKDELK--ENGWIV-----------------EEIKNKKDSLEKINMEILRKNEDMD 8934
Query: 617 HKIWSLEETLQYKEEVILSSHETISERDRL---LKDFIHEKDLMQQRAQETEQKLASRDN 787
+ L Q K+E+ L E +R+ L ++ HEK M+ E + D
Sbjct: 8935 KEKGKLR---QEKQEMDLFRSELQRQREDLETSIQKLTHEKREMEVLRSEIVLEKKDLDQ 8991
Query: 788 EMMHMVLEKDNI------ILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVET 949
+M ++ ++D + I + +I+ + Q + L RD + Q+ +++ E+ + T
Sbjct: 8992 KMKQVIRKRDEMEKIRFDIANARVEIDGERQELEIL----RDNV--QSARQDFERLVERT 9045
Query: 950 IYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSN 1129
+ + + + L LE K ++ +++LK E + + EI +
Sbjct: 9046 ANLEVEESAATDIERLVLEVVKIREMVRNLKGEMERRMEESKVEIDE------------- 9092
Query: 1130 LESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLA---SRIDFLSSECNKLQEQXX 1300
EI+++ + L I Q+R ++ + I++ S ++ + +E + Q++
Sbjct: 9093 ------KEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQE-- 9144
Query: 1301 XXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSK 1480
+ SM K K+ELE+ + I+ E I +++ EL E
Sbjct: 9145 ----------------EESMREILQKEKEELEQLKKDINREKEDI----EISRELVESEI 9184
Query: 1481 SQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHL 1660
+ + + +L+ +T+++ +++ ++V +
Sbjct: 9185 YEGEVKGFTDV-----------------QKYKEELQIVTEELLTKKRNLEQLNSDVQHLM 9227
Query: 1661 DTISSLQTVLSNQKFEIE----KSQKVLQSFESHIEKLVNDS--LHEVDSAFCSLNSRFY 1822
T+ + +K E+E + QK Q E +KL + + E++ +L S
Sbjct: 9228 QTLEEVDIQYIKKKAELEHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINM 9287
Query: 1823 SLIHK---VDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDIL 1993
++ K ++ E LR + + Q Q ++E+E L++ +
Sbjct: 9288 EILQKREDMEKEKENLRREKQETELFRGELQRQ------RDEVESSRQALIMEKDQFKLK 9341
Query: 1994 SWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYF 2173
+R E + + E L+++ DLE +A+ A +SL++ + K
Sbjct: 9342 IDHQRNEMSAAFEKEH--------KRLENMENDLENQRAKLA-ESLNDAAKMEQKLQQMK 9392
Query: 2174 SQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKL 2353
++L +E + E K+ ++ + R+ + +I + H +KK
Sbjct: 9393 NELNKEKEQVEEMKQMVKTERVKIEQEKEEMRKQTQ-----------EIEDGHEKLQKKT 9441
Query: 2354 -LAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELE---LQRKTEEIYDLKRL 2521
+A + A++ L++ + L +Q E E + L R + E+ D K
Sbjct: 9442 EIADKLLQDANSESDRLKDLSMK--LQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIR 9499
Query: 2522 LLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQS 2701
L N+++ + + K E++++E + L + +Q+ + + K ++++
Sbjct: 9500 LKNDRDAYEKD-----------MTHLELKREELVRETEDLERKILQQREQDEMAKRDIEN 9548
Query: 2702 KIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSV 2881
+ ++L E+ + D +L ++ A + H++R+ LL L+ + +E
Sbjct: 9549 QTEAL--EVMKVD----ILKKRNEFAKEMENVHSERQKLLL-----LQGALQSQE----- 9592
Query: 2882 CSDVLTALFVEMVREKEFSLSLATKEQ---------ETVNQKQMSLRKMLEDKDKLLCLV 3034
S++ +F+E +K + A E+ ETV +Q RK++E+ +
Sbjct: 9593 -SELENRVFME--EQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQR----E 9645
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVFLQSE----EREKIEEQKRVLDQALQECEELK 3202
E+ + K QI E+ K++ +N + Q E E+ +E++K L++ E +E++
Sbjct: 9646 KEQLEISKNQI---EQEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQ 9702
Query: 3203 NDIQNKHSDIDS----LREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQ 3370
N I+ + D+++ + E++++ ++ R + + +
Sbjct: 9703 NAIRKEREDLENCWVEIEGEKKRMEEETRRLEMHR------------------EEIKKVD 9744
Query: 3371 LELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKI 3550
EL+ E +++ EK + ++ L++ K E+ +K ++ + ++
Sbjct: 9745 SELQKSRENIESREEKINNKMEELLQMKVEMGRTKEEIEKESQRLQDATID--------- 9795
Query: 3551 LLLESSQSATREQTEKYRDLLN-SLTEEHADLKKQFLSAT----EELQSKERDLEVAMTE 3715
LE++++ + Q +K+ D+++ + E+ ++K Q T EE++ K +DLE+ M +
Sbjct: 9796 --LENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQLDKETKRLSEEIELKVKDLEMEMAD 9853
Query: 3716 TKFLKEKLLVSDENLKEKDLQ 3778
K K++ + + L EK+ Q
Sbjct: 9854 MKRQKQE-IEDTKGLLEKEKQ 9873
Score = 99.8 bits (247), Expect = 9e-18
Identities = 238/1239 (19%), Positives = 502/1239 (40%), Gaps = 68/1239 (5%)
Frame = +2
Query: 302 RKSLETKIAE-TLERMEIHEGDTANTLKNMNFD------------LGQDNPGVPGLLEDI 442
+ LET+I + TLE+ ++ + L+ + D + + + E+I
Sbjct: 8595 KDDLETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANATEEI 8654
Query: 443 RNTKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNK-KIEDLNH 619
+ L+ + + + + + +L + ++EE AA D E +L KI ++
Sbjct: 8655 NRERQELEILRNNVQSARHDFELLLERTANLEDEES----AATDIERLVLEVVKIREMVR 8710
Query: 620 KIWSLEETLQYKEEVILSSHETI-SERDRLLKDFIHEKDLMQQRAQETEQ-KLASRDNEM 793
+ E K +V + E SE R ++D ++ + +E E+ + R+ E
Sbjct: 8711 NLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEK 8770
Query: 794 MHMVL-EKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQ 970
M L EK S+ + + + + + L +DEI + EI +++VE V +
Sbjct: 8771 MRAELAEKQQEQESMREMLHKEREELEQL----KDEINREKEDVEIRRELVEA--VIDKE 8824
Query: 971 ELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQ---AEISKLSHTLEESIMNSNLESL 1141
E+ E D+ KY++E+QS+ +E K+ +++ L T+EE + +
Sbjct: 8825 EMKEFTDI-----QKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKR- 8878
Query: 1142 FTAEIYENTFR-ELGDQISQLRNDMYSKNSYI-DSLASRIDFLSSECNKLQEQXXXXXXX 1315
AE+ F + G+Q+ + + D +N +I + + ++ D L K+ +
Sbjct: 8879 --AELEGIGFELKKGEQLLEKQKDELKENGWIVEEIKNKKDSLE----KINMEILRKNED 8932
Query: 1316 XXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSI 1495
K M++ + EL+ +R E+LE + +QK+ +E E ++ I
Sbjct: 8933 MDKEKGKLRQEKQEMDL----FRSELQRQR----EDLE--TSIQKLTHEKREMEVLRSEI 8982
Query: 1496 XXXXXXXXXXXXXXXXXXXXVVNMAFG------------SKLEELTDQINIFNSVIDKKE 1639
+ + F +LE L D + ++
Sbjct: 8983 VLEKKDLDQKMKQVIRKRDEMEKIRFDIANARVEIDGERQELEILRDNVQSARQDFERL- 9041
Query: 1640 AEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSA--FCSLNS 1813
E + +L+ S T + E+ K ++++++ + +E+ + +S E+D F S
Sbjct: 9042 VERTANLEVEESAATDIERLVLEVVKIREMVRNLKGEMERRMEESKVEIDEKEIFKSEIQ 9101
Query: 1814 RFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLV------LND 1975
R I ++ + L+ ++N + + ++ E + K++ E + +++ L
Sbjct: 9102 RLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQEEESMREILQKEKEELEQ 9161
Query: 1976 FSNDILSWSRRKEEAVVHDDEFDAE----RIALLNELKSLHQDLELLKAEEAVKSLSNNV 2143
DI +R KE+ + + ++E + +++ ++L+++ E K N+
Sbjct: 9162 LKKDI---NREKEDIEISRELVESEIYEGEVKGFTDVQKYKEELQIVTEELLTKK--RNL 9216
Query: 2144 GVSTKGIHYFSQLIQEGKDGEASDVQG-KSRALRRHSTGQAFREPPKPEDLYTTYSEGKI 2320
+ + Q ++E D+Q K +A H T + + E E
Sbjct: 9217 EQLNSDVQHLMQTLEE------VDIQYIKKKAELEHITSEIQKREQILEKQKKKLEENGW 9270
Query: 2321 VEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYEL---ELQRK 2491
+ EE +++ + T ++ + + K + + K++ K+E EL ELQR+
Sbjct: 9271 I----IEEIEMMKV----TLESINMEILQ--KREDMEKEKENLRREKQETELFRGELQRQ 9320
Query: 2492 TEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKM 2671
+E+ ++ L+ EK+ +F+ + QR +M
Sbjct: 9321 RDEVESSRQALIMEKD----------------------QFKLKIDH---------QRNEM 9349
Query: 2672 LCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAG 2851
++E +++++ +++ + + LAE L+DA K Q ++ L K +E
Sbjct: 9350 SAAFEKE-HKRLENMENDLENQRAK---LAESLNDAAKMEQKLQQMKNELNKEKEQVEE- 9404
Query: 2852 ITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCL 3031
++ V++ +EKE + T+E E ++K L+K E DKLL
Sbjct: 9405 ----------MKQMVKTERVKIEQEKE-EMRKQTQEIEDGHEK---LQKKTEIADKLLQD 9450
Query: 3032 VGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEE----L 3199
E+ K L+ +++ E ++E +KR LD+ +E ++ L
Sbjct: 9451 ANSESDRLKDLSMKLQMQRQDIEKT----------NTEMETKKRSLDRMSRELQDDKIRL 9500
Query: 3200 KNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLEL 3379
KND D+ L ++E+L ++ + +L+ L+
Sbjct: 9501 KNDRDAYEKDMTHLELKREELVRE-------------------------TEDLERKILQQ 9535
Query: 3380 RNYNEELKNEIEKKSTDIDLL-----------IKEKEELN---ERLAYTQKAMEQKEAVL 3517
R +E K +IE ++ ++++ KE E ++ ++L Q A++ +E+ L
Sbjct: 9536 REQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQESEL 9595
Query: 3518 VEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDL 3697
++F EQK L + +TE+ R L ++E + ++ EELQ ++ L
Sbjct: 9596 ENRVFMEEQKHL------KQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQREKEQL 9649
Query: 3698 EVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQ 3814
E++ + + K+ L NL E+ L+ E AN E +
Sbjct: 9650 EISKNQIEQEKKDLQNMKSNL-ERQLESLRHEKANVEDE 9687
Score = 99.0 bits (245), Expect = 1e-17
Identities = 237/1220 (19%), Positives = 485/1220 (39%), Gaps = 57/1220 (4%)
Frame = +2
Query: 305 KSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGL 484
K + +IAE L+++ GD +N +L ++ + + + ++ +D+ + L
Sbjct: 1961 KKSQDEIAEQLKQV----GDMMQFTQNEKDNLDRERAAI--IEQKLQMERDMTHLLNREL 2014
Query: 485 YVSNVVSDAVLNGVVSAQE------------EEFKEALAAKDSENFLLNKKIEDLNHKIW 628
+V VLN ++ E+ K L + E L + I + K+
Sbjct: 2015 ESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLE 2074
Query: 629 SLEETLQYKEEVILSSHETISERDRLLKDFIH---EKDLMQQRAQETEQKLASRDNEMMH 799
S+ +TL E + +T++E+ +L + E+D + A+ET++K D + +
Sbjct: 2075 SVLQTLAEDTEKLRI--DTLAEKQKLEDAAVELQKERDEIMNIAEETKRK--REDVDKIR 2130
Query: 800 MVLEKDNIILS-----LHKQIELQSQNTQSLDCFRRD--EIEDQNIKEEIEKQIVETIYV 958
+ +EK I L K+ + Q++ ++D ++D ++ + E+Q ++ + V
Sbjct: 2131 VGIEKQEITFKDLKADLQKEAAIVENQRQAV---QKDIQNVKDMEVQIQKERQYMDRL-V 2186
Query: 959 TQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSK------------------QAEI 1084
+I++ + D +++E K + E++S +DE +E SK QAEI
Sbjct: 2187 EEIEKRTKALDEMQMEVDKERQEVESKRDELE-QETSKLREDEDEFSRQKEKNNIIQAEI 2245
Query: 1085 SKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLR-NDMYSKNSYIDSLASRIDF 1261
K S LE + + N+ E T EL + LR N+ K ID L +++
Sbjct: 2246 QKESDNLE--LQSENISK-------ERTIFELEKEHLGLRENEAEYKQKQIDELQNKLRM 2296
Query: 1262 LSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISK 1441
+ ++Q +K + + + L+++ +E + E E + K
Sbjct: 2297 EKVQVEQMQADKDQQRKKAEY-------VKTARGRETTALEEQ-RQEMESLREEYENVEK 2348
Query: 1442 LQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNS 1621
+K NE E +S+ + E+L Q +F
Sbjct: 2349 QKKHVNEQKELFESRMKSLEMENEAMKKYKEK-----------LDKEYEDLQFQRQLFEK 2397
Query: 1622 VIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFC 1801
I + E+ + I + L QK + +L++ + +EK D L EV
Sbjct: 2398 EIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDEV----- 2452
Query: 1802 SLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFS 1981
+ + + +V+ L +Q + +SQE+ + K+ L+ L N+ +
Sbjct: 2453 --RKKINADLSEVEKQKSAL------VQMNLKISQEESYVKKEKDRLK-----LQENEQN 2499
Query: 1982 NDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQD-LELLKAEEAVKSLSNNVGVSTK 2158
+ + ++ E E + ++ L N + L ++ +E+ K ++ V + N V
Sbjct: 2500 MQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITKEKQRVNEMQNEVKRKNA 2559
Query: 2159 GIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPT 2338
+ Q + +D ++ L R E
Sbjct: 2560 SVDLIKQEVLREQD----HIENSREILNR--------------------------ELEKI 2589
Query: 2339 EEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKR 2518
+EKK + FE D K++++G Q +K E LQ++ E+ +R
Sbjct: 2590 KEKKTILAEEFEALD---------DKKEMIGKEMQRLGKMKAE----LQKEAEDTEKQRR 2636
Query: 2519 LLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQ 2698
+ N++ V ++ + + + + EE L V K+ L+
Sbjct: 2637 DIDNDRRN-----------NEEMVIKLQNEKKDIETSTDRIRDEEAN----LRVQKQRLE 2681
Query: 2699 SKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTS 2878
S D+L KE + + + + L+K Q ES +H L +REI
Sbjct: 2682 SDRDTLEKERFDLEKTKTEMKD-----LEK-----QLESQSRQHEIQLVEIQKEREI--- 2728
Query: 2879 VCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQ--MSLRKMLEDKDKLLCLVGEENKE 3052
L L + + ++KE KE++ +++ +SLR+ LE++ + + +
Sbjct: 2729 -----LEQLKINLSKQKED----LEKERDCFEKEKADISLREELEEQSEKEG-IDKTRVR 2778
Query: 3053 HKRQIAILEKLK----EETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNK 3220
K+++ LE+ + +E ENN + + +ER+KIE+ K L + ++ E+ + DI+N
Sbjct: 2779 IKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIEND 2838
Query: 3221 HSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEEL 3400
+ + + + + K + L+ + +L+ N E+
Sbjct: 2839 RRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEM 2898
Query: 3401 KN-----EIEKKSTDIDLL-IKEKEELNERLAYTQKAMEQKEAVLVEK-LFEGEQKILLL 3559
K+ E + + +I L I+++ E+ E+L T +QKE + E+ FE E+ + L
Sbjct: 2899 KDLEKQLESQNRQHEIQLAEIQKEREILEQLKLT--LSKQKEDLEKERDCFEKEKADISL 2956
Query: 3560 --ESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKE 3733
E + + RE K R + +E +LK+ L+ +EL++ E ++ E +++
Sbjct: 2957 REELQEQSEREGIGKTR---VRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQ 3013
Query: 3734 KLLVSDENLKEKDLQLRAFE 3793
+ ++ + Q R E
Sbjct: 3014 IKAELQKEAEDTEKQRRDIE 3033
Score = 94.4 bits (233), Expect = 4e-16
Identities = 243/1244 (19%), Positives = 500/1244 (40%), Gaps = 68/1244 (5%)
Frame = +2
Query: 293 LDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTV 472
+ T+ + KI+E + + + + +K +DL Q + D+ + + +
Sbjct: 1897 IKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQ-------MQTDLNRQQKEMQDI 1949
Query: 473 ESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQY 652
++ +++ + + +Q+E ++ D F N+K + +E+ LQ
Sbjct: 1950 QNAVFMEK-------SELKKSQDEIAEQLKQVGDMMQFTQNEKDNLDRERAAIIEQKLQM 2002
Query: 653 KEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILS 832
+ ++ + + + K+ ++EK L++ + + +D E M + LE++
Sbjct: 2003 ERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRDM--QDLEQMKINLEREK---- 2056
Query: 833 LHKQIELQSQNTQSLDCFRRDEIED--QNIKEEIEKQIVETIYVTQIQELGEEHDLLRLE 1006
++++LQ Q+ +D++E Q + E+ EK ++T+ + Q+L + +E
Sbjct: 2057 --EEMQLQRQSIAE----EKDKLESVLQTLAEDTEKLRIDTL--AEKQKLEDA----AVE 2104
Query: 1007 SAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLE-ESIMNSNLESLFTAE--IYENTFRE 1177
K +DEI ++ +E K + ++ K+ +E + I +L++ E I EN +
Sbjct: 2105 LQKERDEIMNIAEETKRK----REDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQA 2160
Query: 1178 LGDQISQLRN---DMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTL 1348
+ I +++ + + Y+D L I+ + +++Q +
Sbjct: 2161 VQKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVD---------------- 2204
Query: 1349 KASMEMQCSKLKDELEEERGKISENLERISKLQKMNNEL-AERSKSQNSIXXXXXXXXXX 1525
K E++ + DELE+E K+ E+ + S+ ++ NN + AE K +++
Sbjct: 2205 KERQEVESKR--DELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKE 2262
Query: 1526 XXXXXXXXXXV---VNMA--FGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVL 1690
+ N A +++EL +++ + +++ +A+ ++T
Sbjct: 2263 RTIFELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTAR 2322
Query: 1691 SNQKFEIEKSQKVLQSFESHIE------KLVNDSLHEVDSAFCSL---NSRFYSLIHKVD 1843
+ +E+ ++ ++S E K VN+ +S SL N K+D
Sbjct: 2323 GRETTALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKYKEKLD 2382
Query: 1844 NSGETL----RAFVKNIQNQVAVSQ--EQHIEHQCKE--------ELEGHIADL---VLN 1972
E L + F K IQ Q ++IE + KE E ++ + V+
Sbjct: 2383 KEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVE 2442
Query: 1973 DFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVS 2152
D L R+K A + + E + +N LK ++ + K ++ +K N +
Sbjct: 2443 KSKTDELDEVRKKINADLSEVEKQKSALVQMN-LKISQEESYVKKEKDRLKLQENEQNMQ 2501
Query: 2153 TKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPH 2332
SQL K E + Q + +R + + + E + T + ++ E
Sbjct: 2502 ------MSQL--NAKQNELDERQAEMEKQKREL--ENVMDRLEKEKVEITKEKQRVNEMQ 2551
Query: 2333 PTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKT------ 2494
++K ++ D + +EQ H + S L RE E ++KT
Sbjct: 2552 NEVKRKNASV---------DLIKQEVLREQ--DHIENSREILNRELEKIKEKKTILAEEF 2600
Query: 2495 EEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKML 2674
E + D K ++ E L AE+ + E ++ + + + +M+
Sbjct: 2601 EALDDKKEMIGKEMQRL-----------GKMKAELQKEAEDTEKQRRDIDNDRRNNEEMV 2649
Query: 2675 CVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLS---DALKKSADHAQRESHLLKHIADLE 2845
L+ E + I++ I+++++N +V ++L D L+K ++ +K DLE
Sbjct: 2650 IKLQNE-KKDIETSTDRIRDEEANLRVQKQRLESDRDTLEKERFDLEKTKTEMK---DLE 2705
Query: 2846 AGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLL 3025
+ + R+ E L KE+E + Q +++L K ED +K
Sbjct: 2706 KQLESQS------------------RQHEIQLVEIQKEREILEQLKINLSKQKEDLEKER 2747
Query: 3026 CLVGEENKEHKRQIAILEKLKEETEN---NPGRVFLQSE-------------EREKIEEQ 3157
+E K I++ E+L+E++E + RV ++ E E E E Q
Sbjct: 2748 DCFEKE----KADISLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQ 2803
Query: 3158 KRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXX 3337
K++++ + E++K ++Q + D + R++ E + M
Sbjct: 2804 KQIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRI 2863
Query: 3338 XXISSNLDSMQLELRNYNEELKNE---IEKKSTDIDLLIKEKEELNERLAYTQKAMEQKE 3508
+NL ++ L + + L+ E ++K +T++ L K+ E N R Q A QKE
Sbjct: 2864 RDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQN-RQHEIQLAEIQKE 2922
Query: 3509 AVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKE 3688
++E+L K+ L S +E EK RD +E AD +S EELQ +
Sbjct: 2923 REILEQL-----KLTL-----SKQKEDLEKERDCFE---KEKAD-----ISLREELQEQS 2964
Query: 3689 RDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQYQ 3820
+ T + KE + LK+ L + E+ N+E Q Q
Sbjct: 2965 EREGIGKTRVRIKKEM-----DELKQTRLNV-VKELENNELQKQ 3002
Score = 94.0 bits (232), Expect = 5e-16
Identities = 221/1220 (18%), Positives = 488/1220 (40%), Gaps = 53/1220 (4%)
Frame = +2
Query: 284 DGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLL 463
DG + + ++ E+L + +GD L+ M D + + + + + + L
Sbjct: 10381 DGKRNEINKEQQRLEESLRAINEEKGD----LEIMRADYEKQEQQIEEMRVEAKMERKEL 10436
Query: 464 DTVESGLYVSNVVSD---AVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSL 634
D ++S L D LN + E+E + L SE +++ED
Sbjct: 10437 DQIKSELEKDKTEIDYEWKKLNNDRNMIEKE-RNDLEKMKSELMTQRQQMED-------- 10487
Query: 635 EETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEK 814
+ E+ E +E+D++ K+ K+++++ E E++ + + LE+
Sbjct: 10488 -----ERSELDQKIKEANTEKDKIEKN----KEIVERLMAEVEEQRNDFKLKKEELALER 10538
Query: 815 DNII----LSLHKQIELQSQNTQ----------SLDCFRRDEIEDQNIKEEIEKQIVETI 952
NI+ L + ELQ+++ Q + + E Q K+EI+ I ET
Sbjct: 10539 QNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETS 10598
Query: 953 YVTQ-IQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSN 1129
+ ++++ ++ + E +D ++ ++E + K Q I + + + +
Sbjct: 10599 RQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQ-KEED 10657
Query: 1130 LESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXX 1309
L + E E+ +I +++ ++ I+ + L + K +E+
Sbjct: 10658 LTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAMT 10717
Query: 1310 XXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISK----LQKMNNELA--- 1468
+K+ + + K E++ E+ K++++++ I + L+KM +E+
Sbjct: 10718 IKLKMEREDLDQIKSELVRE----KTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQK 10773
Query: 1469 -ERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAE 1645
E K ++ + V + F ++EE +I + +D + +
Sbjct: 10774 QEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMF--EVEEQRHEIQLQKEELDIERQK 10831
Query: 1646 VSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYS 1825
++ D + ++ L N+ I +V+ K ++L E+++ S
Sbjct: 10832 IADEQDLLIQNKSELQNENERIRNINEVI--------KKERETLKEMEAHLEKEKEEMKS 10883
Query: 1826 LIHKVDNSGETLRAFVKNI--QNQVAVSQEQHIEHQCKEELEGHIADLV--LNDFSNDIL 1993
+ + E L +I QNQ + Q +E + KE++ L +++F +
Sbjct: 10884 ITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQE-KEDINHEWTQLQQRIDEFDAQV- 10941
Query: 1994 SWSRRKEEAVVHDDEFDAERIAL------LNELKSLHQDLELLKAEEAVKSLSNNVGVST 2155
S++KEE + E ER +L + E+K+ +LE +K E+ + + V
Sbjct: 10942 --SKQKEEDLTKQKEMKEERKSLEETKARIIEMKT-KAELEDIKKEKEKEEEEEEMRVKV 10998
Query: 2156 KGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHP 2335
+ DG+ D + KS R S + E K D + KI+E
Sbjct: 10999 E------------MDGKELD-RIKSELKRERS--EIDHEQKKLND------DKKIIEQEK 11037
Query: 2336 TEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLK 2515
+K+ K +++ +Q E EL+ K ++ Y K
Sbjct: 11038 QNLEKM--------------------KSEIMKQRQQM-----EEERSELENKIKQTYIEK 11072
Query: 2516 RLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENK---LLPVEEVQRYKMLCVLK 2686
+ N K EI K ++E K EE+ + +
Sbjct: 11073 CDIENSK-------------------EIVQKLMVEVEEQKHEIQFQKEELDIERQKIADE 11113
Query: 2687 EELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDRE 2866
++L + S L+ E+ N + +K + LK+ H +++ +K +++ + +E
Sbjct: 11114 QDLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRL--KE 11171
Query: 2867 IMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEEN 3046
+ + +DV +++ +++ L +E+E +N K L++ +++ D + E++
Sbjct: 11172 DLEKMSTDV-NKQNKDLMNQRD----LLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQD 11226
Query: 3047 -------KEHKRQI------AILEKLKEETENNPGRVFLQSEEREKIEEQKRVL-DQALQ 3184
KE ++ + I K K E E ++EE E+ EE+ RV+ + +
Sbjct: 11227 LPKEKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERK 11286
Query: 3185 ECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDS 3364
E ++K++++ S+ID EQ+KLN ++ + +
Sbjct: 11287 ELYQIKSELERVRSEID---HEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSE 11343
Query: 3365 MQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQ 3544
+ +++ N E K++IEK ++ L+ E EE + + QKE + +E+ ++
Sbjct: 11344 LDNKIQQTNLE-KHDIEKSKEIVEKLMVEVEEQRKDIQL------QKEELDIERQKIADE 11396
Query: 3545 KILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKF 3724
+ LL++ +++ + + E+ + + + +E L++ + L+ ++ +L + ET+
Sbjct: 11397 QNLLVQ-NKAKLQNENERIKKVDEEIKKERETLREMEI----HLKKEKEELRSIIEETQR 11451
Query: 3725 LKEKLLVSDENLKEKDLQLR 3784
KE L ++ E+ L L+
Sbjct: 11452 RKEDLEKMSTDINEQKLHLK 11471
Score = 93.2 bits (230), Expect = 8e-16
Identities = 235/1268 (18%), Positives = 500/1268 (39%), Gaps = 170/1268 (13%)
Frame = +2
Query: 527 VSAQEEEFKEAL--AAKDSENFLLNKKI-EDLNHKIWSLEETLQYKEEVILSSHETISER 697
+ + +E K+ K+ EN L K+I ED KI ++ LQ + E +T +R
Sbjct: 2976 IKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAE------DTEKQR 3029
Query: 698 DRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSL 877
+ KD + ++++ + E + S D + + L + KQ ++T
Sbjct: 3030 RDIEKDRRNNEEMVIKLQNEKKDIETSTDR------IRDEEANLEVQKQRLESDRDTLEK 3083
Query: 878 DCF--RRDEIEDQNIKEEIEKQIVE-TIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDE 1048
+ F + + E N+K+++E QI + I + +IQ+ E + L++ +K +++++ +D
Sbjct: 3084 ERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERD- 3142
Query: 1049 CHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNS 1228
C KE +A+IS LS L+E +++ T ++ D++ + R ++ +K
Sbjct: 3143 CFEKE---KADIS-LSEDLKEQSEREGIDNTRTR------IKQEMDELEKTRQNL-AKEQ 3191
Query: 1229 YIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERG 1408
+ L +I + E +K+++ +KA ++ + K K EL+ ER
Sbjct: 3192 ENNELQKKI--IEDERDKIEQ------------------IKAELKKEAEKTKLELQNERQ 3231
Query: 1409 KISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLE 1588
+ E ++ K ++ LAE + + + +
Sbjct: 3232 NLEEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIELKK 3291
Query: 1589 ELTD----QINIFNSVIDKKE------AEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQS 1738
+TD + ++ N +++++E AE+ D + L+ +S Q+ +I + L+
Sbjct: 3292 TVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQLRL 3351
Query: 1739 FESHIEKL---VNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQE 1909
E +E+L + E+++ ++ + Y L + R N + A
Sbjct: 3352 REVELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREV--NQMMEYASKDR 3409
Query: 1910 QHIEHQCKEEL-EGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSL- 2083
++E + E + + H D+ LN I R + ++ E D +R AL E+K L
Sbjct: 3410 ANLEKEKSEMIAQKHQMDIELNKERGLI---EERTQMLNTYEKEMDQKRTALEVEMKELK 3466
Query: 2084 --------------HQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEA---S 2212
+EL + + +K L + + ++ +++ KD A
Sbjct: 3467 YHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLAHLAE 3526
Query: 2213 DVQGKSRALR-RHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAI---LAFETA 2380
D + K ++ H + A + K S K E +E+KK++ L A
Sbjct: 3527 DTKRKDDEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQQMQA 3586
Query: 2381 DASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXX 2560
+ + K+ ++ + + + ++ EL +++E++ + +L EK L +
Sbjct: 3587 EINRQQTEMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLTEKELLESDRK 3646
Query: 2561 XXXXXXXXXVAE---ITGKFEKVLQENKLLP----------------VEEVQRYKM---- 2671
+ I E + Q+ +LL EE+++ K+
Sbjct: 3647 LLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQH 3706
Query: 2672 -----------LCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLS--DALKKSADHAQRE 2812
+ +E LQ D++ +EI + K + +K D LK + Q+E
Sbjct: 3707 ERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQE 3766
Query: 2813 SH-----LLKHIADLEAGITDREIMTSVCSDVLTALFVEMVR------EKEFSLSLATKE 2959
++K ++L+ ++ + + +D++ + E + E E KE
Sbjct: 3767 LEKEKEIIMKDRSELDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKE 3826
Query: 2960 QETVNQ---------KQMSLRKML--EDKDKLLCLVGEENK-EHKRQIAILEKLKEETEN 3103
+ +Q K M L+K + E+K+KL E+ K E +R+ + K+KEE +N
Sbjct: 3827 KHDFDQGRNSLDEDLKMMKLQKQVFEEEKNKL-----EQMKIELEREAGEIRKIKEEIQN 3881
Query: 3104 NPGRVFLQSEE--REK---------IEEQKRVLDQALQECEELKNDIQNKHSDIDSLRE- 3247
+ +EE REK ++++ +LD+ E L ++Q + S+ + +RE
Sbjct: 3882 ERQSLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMREN 3941
Query: 3248 -------------------------------EQEKLNKQLRCMXXXXXXXXXXXXXXXXX 3334
+Q ++ K+ +
Sbjct: 3942 ISKQTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHK 4001
Query: 3335 XXXISSNLDSMQLELRNYNEE------LKNEIEKKSTDIDLL------------------ 3442
+ + +S++L+ + E +K E+E+++ +I+ +
Sbjct: 4002 IISLDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQI 4061
Query: 3443 IKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSL 3622
KE++++N + T + K+ VL EK + E+KI ++S + ++ + L
Sbjct: 4062 TKERDKINNLIEETNR----KDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSEL 4117
Query: 3623 TEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEK--DLQLRAFEI 3796
+ DL+KQ + E+Q + DLE ++ +E +K+K +L EI
Sbjct: 4118 YKVKEDLEKQKENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEI 4177
Query: 3797 ANSEKQYQ 3820
N +++ +
Sbjct: 4178 QNLQQELE 4185
Score = 91.7 bits (226), Expect = 2e-15
Identities = 261/1407 (18%), Positives = 533/1407 (37%), Gaps = 232/1407 (16%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAET-LERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRN 448
+EVE+ RK ++ + E +ER +I D N L L +N + + E+I+
Sbjct: 11370 VEVEE----QRKDIQLQKEELDIERQKI--ADEQNLLVQNKAKLQNENERIKKVDEEIKK 11423
Query: 449 TKDLLDTVESGLYVSNVVSDAVLNGVVSAQEE------EFKEALAAKDSENFLLNKKIED 610
++ L +E L +++ +E+ + E ++ LL ++ E+
Sbjct: 11424 ERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREE 11483
Query: 611 LNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNE 790
+NH++ L++ + + + E +++++ + K L + +A+ E K + E
Sbjct: 11484 INHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEE----RKSLEETKARIIEMKTKAELQE 11539
Query: 791 MMHMVLEKDNIILSLHKQIELQSQNTQSLDCFR-RDEIEDQNIKEEIEKQIVE------- 946
+M E+D + + ++E + N + R R EI+ + K +K+I+E
Sbjct: 11540 IMQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLE 11599
Query: 947 ---TIYVTQIQELGEE---------------HDL--------------------LRLESA 1012
+ +TQ Q++ EE HD+ +RL+
Sbjct: 11600 KMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKE 11659
Query: 1013 KYQDEIQSLKDEC---------------HAKEMSKQAEISKLSHTLEESIMNSNLESLFT 1147
+ E Q + DE KEM + EI K TL+E + E
Sbjct: 11660 ELDIERQKIADEQGLVVQNKAKLQNENERIKEMDE--EIKKEKETLKEMEAHLRKEKEEM 11717
Query: 1148 AEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXX 1327
+ E T R + + ++ D+ +N L ++ D L E ++ +
Sbjct: 11718 RSVIEETQRRKKEDLEKMSTDVNKQNQ---DLMNQRDLLKQEREEINHKWTQLQQRID-- 11772
Query: 1328 XXXXXTLKASMEMQCSKLKDE-------LEEERGKISENLERISKLQKMNNE---LAERS 1477
+ Q SK K+E +EEER + E +I +++ E+
Sbjct: 11773 ---------EFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKE 11823
Query: 1478 KSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSV---IDKKEAEV 1648
K + + V + ++L D + ++K ++E+
Sbjct: 11824 KEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEI 11883
Query: 1649 SGHLDTISSLQTVLSN-------QKFEIEKSQKVLQSFESHIEKLVND---SLHEVD--- 1789
+ ++ L N ++ +IE S++++Q +E+ D E+D
Sbjct: 11884 MKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIER 11943
Query: 1790 --------------SAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQE--QHIE 1921
+ + N R + ++ ETL+ +++ + + + +
Sbjct: 11944 QKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQ 12003
Query: 1922 HQCKEELEGHIADLVLNDFSNDILSWS---RRKEEAVVHD--------DEFDAERIALLN 2068
+ KE+LE D+ N + D+++ +++ E + H DEFDA+
Sbjct: 12004 RRQKEDLEKMSTDV--NKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQ------ 12055
Query: 2069 ELKSLHQDL-ELLKAEEAVKSLSNN-VGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALR 2242
K +DL + K EE KSL + + + I++ K+ E +V ++
Sbjct: 12056 VSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMK 12115
Query: 2243 RHSTGQA------------FREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADA 2386
+ Q + +D E + +E +E K + E ++
Sbjct: 12116 KEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSEL 12175
Query: 2387 SDSPLRNWPKEQLLGHFKQSFAGL-----KREYELELQRKT-----EEIYDLKRLLLNEK 2536
+ + + ++ + + K+ L ++++E++ Q++ ++I D + LL+ K
Sbjct: 12176 ENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNK 12235
Query: 2537 NGLH------AXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKM--------L 2674
+ L + E+ EK +E K + EE +R K +
Sbjct: 12236 SELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSI-TEETRRQKEDLEKMSTHI 12294
Query: 2675 CVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGI 2854
K++L+S+ D L +E +E + K L +++ + + + Q+E L K E
Sbjct: 12295 NEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSK--QKEEDLPKEKEMKEDRK 12352
Query: 2855 TDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLV 3034
+ E ++ A E+ +EKE +EQE + +M +++ + K +L +
Sbjct: 12353 SLEETKANILEMKTKAEPEEIKKEKEKE----EEEQEMRVKVEMERKEIEQIKSQLERVR 12408
Query: 3035 GEENKEHKR---QIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKN 3205
E + E K+ ++E+ KE+ E + Q R+++EE++ LD+ +++ + K+
Sbjct: 12409 SEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQ---RQQMEEERSELDKKIKQTDLEKH 12465
Query: 3206 DIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXIS------------ 3349
DI+N ++ L E EK +++
Sbjct: 12466 DIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQQNENERIKE 12525
Query: 3350 ---------SNLDSMQLELRNYNEEL----------KNEIEKKSTDI-----------DL 3439
L M++ L+ EE+ K ++EK STDI DL
Sbjct: 12526 MDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDL 12585
Query: 3440 LIKEKEELNERLAYTQKAMEQKEAV----------------------------LVEKLFE 3535
L +E+EE+N +L Q+ +++ E ++E+
Sbjct: 12586 LKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNR 12645
Query: 3536 GEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTE 3715
++ +E QS + E +DLL +E D +K+ EELQ + DLE+ M E
Sbjct: 12646 KRTELEEIEVDQSQQNKNVETMKDLLE---KERKDTEKE----REELQKQADDLEMQMIE 12698
Query: 3716 TKFLKEKLLVSDENLKEKDLQLRAFEI 3796
KE++ + ++K L+ +A EI
Sbjct: 12699 HGD-KEEMSKRSLDEEKKLLEQKANEI 12724
Score = 90.5 bits (223), Expect = 5e-15
Identities = 236/1241 (19%), Positives = 467/1241 (37%), Gaps = 149/1241 (12%)
Frame = +2
Query: 539 EEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISER-DRLLKD 715
+ E ++ + +LN + ++LN +LE+ KEE L S R + LL+D
Sbjct: 13249 QAELQKGQLEMEMHQLMLNSERDELNGMRVNLEKQ---KEEFELMQQNLESRRPESLLED 13305
Query: 716 FIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQ----SLDC 883
+ EK +++ A + ++ N M + + I KQIE + + Q L+
Sbjct: 13306 ILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKI-----KQIEGEIKTKQIEMACLEE 13360
Query: 884 FRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSL-----KDE 1048
++ E+++Q E E Q ++Q EE ++ E +DEIQ L K++
Sbjct: 13361 LKQKELDEQKNMRECENQ--------ELQMRREELAKMKTEIDIERDEIQKLRKQYEKEK 13412
Query: 1049 CHAKEMS---KQAEISKLSHTLEESIMNSNLESL---------FTAEIYENTFRE---LG 1183
C +++ ++ E K+ ++ ++ ++SL A++ +N RE +
Sbjct: 13413 CELEQIKPDLQKREPEKIDAEVQHDEIHGGIDSLKEEREEIEKMKADL-QNKLREAENMR 13471
Query: 1184 DQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTL----- 1348
D + + ++++ K + I+ +A + S+ N LQ++ L
Sbjct: 13472 DIMKREKDELEKKEAEIEQMAVETEDNDSDKN-LQDEMMKIEAILKVTKKQKNYLEQMNE 13530
Query: 1349 -----KASMEMQCSKLKDELEEERGKISENLE-RISKLQKMNNELAERSKSQNSIXXXXX 1510
K +E C L+ E E K+ E E +SK++ ER + +I
Sbjct: 13531 NLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKME-------EREAERKTIERVMD 13583
Query: 1511 XXXXXXXXXXXXXXXVVNMAFGSK-----LEELTDQINIFNSVIDKKEAEVSGHLDTISS 1675
+VNM K LEE +++ S + + +E+ +
Sbjct: 13584 EMAEEHEKIKKEREELVNMEEEIKKQRRVLEESMNEMTKKKSELQHERSELYKQKQQLED 13643
Query: 1676 LQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGE 1855
+ + S K +++ + + I K + + ++ + +++ E
Sbjct: 13644 M--IASESKRDVDTERSRQDKEDEQILKREREEIADMKDQLLKEKEDVETTKERINREKE 13701
Query: 1856 TLRAFVKNIQNQVAVSQEQHIEHQ----CKEELEGHIADLVLNDFSNDILSWSRRKEEAV 2023
+ + +Q +E +E+Q K E++ + L D L R A+
Sbjct: 13702 HIEKMQSQLNDQ---KEEMDLENQKLLYMKTEIQ--VKTNALEKMMQD-LQKERENVNAL 13755
Query: 2024 VHDDEFDAERIALL---NELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEG 2194
V + + E+ +L N+ K H + E+ + E ++S+ + + I + ++
Sbjct: 13756 VIQHQKEREQRDILIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTR 13815
Query: 2195 KDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFE 2374
+ E ++ K + + RE E + E K E EK + +
Sbjct: 13816 SE-ELENLIKKQQKEFETKENEMQRERKALEKMNAEL-ERKSTELKNKIEKVTVWEADLQ 13873
Query: 2375 TADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKT-----EEIYDLKRLLLNEKN 2539
L+N + + +++ ++++E+E RKT E + L+ L +EK
Sbjct: 13874 KEKNKTEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKK 13933
Query: 2540 GLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLL 2719
+ + EI + E + +E K L + + L ++ L
Sbjct: 13934 SMLSRLSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKL 13993
Query: 2720 KEIKEKDSNSKVLA------EKLSDALKKSA--------------DHAQRESHLLKHIAD 2839
+EKDS ++ A EKL + ++K+ D ++E L AD
Sbjct: 13994 SIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRAD 14053
Query: 2840 LEAGI-----------TDREIMTSVCSD---------------------------VLTAL 2905
+E T++EI+ ++ L +
Sbjct: 14054 IERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEKQRKRNDLTLQELRKEKMALEQM 14113
Query: 2906 FVEMVREKEFSLSLATK---EQETVNQKQMSLRKMLEDKDKL-LCLVGEENKEHKRQ--- 3064
++ +EK+ SL + +Q + K+ L + ++ D L + L +N +K+Q
Sbjct: 14114 ITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEV 14173
Query: 3065 -IAILEKLKEETENNPGRVFLQSEERE------KIEEQKRVLD-------QALQECEELK 3202
+ I+E +K + + L E R+ E+QK VL Q E E+
Sbjct: 14174 DVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFT 14233
Query: 3203 NDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELR 3382
DI+ + ++ REE + LNK++ L S+ LE+
Sbjct: 14234 TDIKTEKEHVEKEREEIDVLNKEI---------------------IKSKEELQSLNLEI- 14271
Query: 3383 NYNEELKNEIEKKSTDIDLLIKEKEEL------NERLAYTQKAM------EQKEAVLVEK 3526
E K EI K I+ L + + +L + L T+K M ++ E L
Sbjct: 14272 ---EMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMN 14328
Query: 3527 LFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVA 3706
L + + ++ L ++ A + Q E + +L+ +E D+ S + L+ ++ +L
Sbjct: 14329 LQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKL 14388
Query: 3707 MTETKFLKEKLLVSDENL-----KEKDLQLRAFEIANSEKQ 3814
+ L EK+ E L KE+D +I SEKQ
Sbjct: 14389 ---SHVLNEKVQREQEELERLLEKERDDIENCKKIIESEKQ 14426
Score = 87.8 bits (216), Expect = 3e-14
Identities = 268/1329 (20%), Positives = 516/1329 (38%), Gaps = 159/1329 (11%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNT 451
+EVE+ D R E +ER +I D + L +N + + E+I+
Sbjct: 11923 VEVEEQRKDIRLQKEEL---DIERQKI--ADEQGLVVQNKAKLQNENERIKEMDEEIKKE 11977
Query: 452 KDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENF-------LLNKKIED 610
K+ L +E+ L +V+ Q+E+ ++ + +N LL ++ E+
Sbjct: 11978 KETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREE 12037
Query: 611 LNHKIWSLEETL--------QYKEEVILSSHETISERDRLLKDFI--------------- 721
+NHK L++ + + KEE + + ER L + I
Sbjct: 12038 INHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIK 12097
Query: 722 -----HEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCF 886
E+++M+ + + +++L +++ + E D+ L+ ++ Q + L+
Sbjct: 12098 KEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKM 12157
Query: 887 R-------------RDEIED------------QNIKEEIEKQIVETIYVT-QIQELGEEH 988
+ R E+E+ +N KE ++K +VE +IQ EE
Sbjct: 12158 KSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEEL 12217
Query: 989 DLLRLESAKYQDEIQSLKDEC-HAKEMSKQAE--ISKLSHTLEESIMNSNLESLFTAEIY 1159
D+ R + A QD + K E + E K I K TL+E E I
Sbjct: 12218 DIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSIT 12277
Query: 1160 ENTFRELGD------QISQLRNDMYSKNSYIDS-----------LASRIDFLSSECNKLQ 1288
E T R+ D I++ + D+ S+ ++ L RID ++ +K +
Sbjct: 12278 EETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQK 12337
Query: 1289 EQXXXXXXXXXXXXXXXXTLKAS-MEMQCSKLKDELEEERGKISENLERISKLQKMNNEL 1465
E+ KA+ +EM+ +E+++E+ K E E K++ E+
Sbjct: 12338 EEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEI 12397
Query: 1466 AERSKSQ-----NSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVID 1630
E+ KSQ + + + M S++ + Q+ S +D
Sbjct: 12398 -EQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMK--SEIMKQRQQMEEERSELD 12454
Query: 1631 KK-------EAEVSGHLDTISSLQTVLSNQKFEIEKSQKVL----QSFESHIEKLVNDSL 1777
KK + ++ + + L + QK EI+ ++ L Q + L+ + +
Sbjct: 12455 KKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKI 12514
Query: 1778 HEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIA 1957
+ + N R + ++ ETL+ N+Q + KEE+E I
Sbjct: 12515 EQQNE-----NERIKEMDEEIKKERETLKEMEVNLQKE-------------KEEIESVIE 12556
Query: 1958 DLV-----LNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAV 2122
+ L S DI + +K++ + D ER + ++L L Q ++ +
Sbjct: 12557 ETQRRKEDLEKMSTDI---NEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFET---- 12609
Query: 2123 KSLSNNVGVSTK---GIHYFSQLIQEGKDGEA--SDVQGKSRALRRHSTGQAFREPPKPE 2287
++N+ V+TK +L Q K+ E+ + K L Q+ +
Sbjct: 12610 ---TSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTELEEIEVDQSQQNKNVET 12666
Query: 2288 DLYTTYSEGKIVEPHPTEEKKL---LAILAFETADASDSPLRNWPKEQLLGHFKQSFA-- 2452
E K E E +K L + E D + R+ +E+ L K +
Sbjct: 12667 MKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILR 12726
Query: 2453 ---GLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVL 2623
L++E E ++ +K E+ L++ + N+KN + + E +K L
Sbjct: 12727 QRDDLEKEKE-DMMKKWNELDGLQKEIQNQKNEMEEIKCELETKRIEIIKE-----QKRL 12780
Query: 2624 QENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIK-EKDSNSKVLAEKLSDALKKSADH 2800
+E+ EE Q +++ V E+ Q +I+ + + K E+D +++A+ L D
Sbjct: 12781 EESLNTVNEERQYLEIVRVDYEKHQQQIEEMRVKTKMERDELDQLMAKMLMD-------- 12832
Query: 2801 AQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQK 2980
++E+ K D++ L EM + K F+L +E + QK
Sbjct: 12833 -RKENERSK--------------------DMIGLLKKEMEQTK-FNLDAQEEELKLEKQK 12870
Query: 2981 QMSLRKMLEDKDKLLCLVGEENKEHKRQ-----IAILEKLKEETENNPGRVFLQSE---- 3133
+ +K LE + E K K Q E LKEE + PG+ F+Q +
Sbjct: 12871 IQNEKKDLEMFKAEIKREASEVKTLKEQQLEKDTKAFEALKEE--HLPGQ-FVQQKGGEF 12927
Query: 3134 EREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSL-----REEQEKLNKQLRCMXXXXX 3298
ER +I+E KR+L + +E +EL+ + Q ++L ++ E+L+ L
Sbjct: 12928 ERIQIDEVKRILSEIHKEKKELERNKQILEHQREALLEIKSKQPSERLDVILVSSATQTS 12987
Query: 3299 XXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLA 3478
+ + D ++ + +E + EI+K D +K E + ++A
Sbjct: 12988 DLEDIPDVSASQGETVEKHTDIIKEYTTSIPKE-EYEIDKLKQQGDKKLKSTRE-DTKMA 13045
Query: 3479 YTQKAMEQK---EAVLVEKLFEGE--------------QKILLLESSQSATREQTEKYRD 3607
T+ + K + ++ KL G+ +++ + + + + +++ EK R
Sbjct: 13046 DTEVTTQYKYIPDPSIMMKLESGKDETDGLTEVHTTERRELEITKLALQSEQQEIEKIRQ 13105
Query: 3608 LL----NSLTEEHADLKKQF-------LSATEELQSKERDLEVAMTETKFLKEKLLVSDE 3754
+ N L + +DL+KQ+ + E E DLE + ETK +E+L +
Sbjct: 13106 DIDREKNDLEKYRSDLEKQYEEMEICKQNIENERAELEIDLENIIIETKSKQERLESIEV 13165
Query: 3755 NLKEKDLQL 3781
L+EK++Q+
Sbjct: 13166 QLQEKNVQM 13174
Score = 85.1 bits (209), Expect = 2e-13
Identities = 232/1247 (18%), Positives = 476/1247 (38%), Gaps = 81/1247 (6%)
Frame = +2
Query: 266 SFIEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIR 445
S I+V+ ++ + K + +E+M+ D N L+ D+ + + D++
Sbjct: 279 SAIQVQINEIEMKIGETQKAKDLMEQMKAEIEDEKNELEKKKEDIKRQRDQFEQIKLDLQ 338
Query: 446 NTKDLLD-----TVESGLY------------------VSNVVSDAVLNGVVSAQEEEFKE 556
K ++ T + GL + V + N S QE
Sbjct: 339 QVKMEMEQRWHETEKEGLEQRAVIQREKEQLKYLQDEIQRVREEVERNREFSKQEHARIS 398
Query: 557 ALAAKD-SENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEKD 733
L A+ EN L+ K D+ K LEE K E+ ER R ++ + +
Sbjct: 399 QLRAQALEENNLIENKWHDILRKEKDLEEM---KHEI---------ERGR--EELVMNGE 444
Query: 734 LMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQN 913
L+++ ++ EQ + M+ M D I + ++++ + D + + + +
Sbjct: 445 LVKKEWEKIEQAKVDIQSHMISMEGRVDEIKRETERLKHIKTEMQRDKDALEKQKDDTRK 504
Query: 914 IKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKL 1093
KEE E++ E VT+ E R E + E+Q + D AK + ++ E ++
Sbjct: 505 AKEEAERKRYEI--VTEELEHRARLQRERDELENIRAEMQRVNDVEKAKILKEKEESIRI 562
Query: 1094 SHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSE 1273
EE+ L AEI R Q LR + ++L ++ + +S+
Sbjct: 563 R---EEARQERETTELVNAEIKAEKERLNQRQEEMLRERQEIERIKHETLRAKEEIENSQ 619
Query: 1274 CNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSK-----LKDELEEERGKISENLERIS 1438
++E K E+Q +K K ELEEER E+LER
Sbjct: 620 DVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKEQMEEAKVELEEER----EDLER-- 673
Query: 1439 KLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEEL-TDQINIF 1615
K ++ E+ + +N I V S+ E T+++ +
Sbjct: 674 KRDLVSREIEQAEFLRNEILR-------------------VKEEMESRWRETETEEVEL- 713
Query: 1616 NSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSA 1795
A+ L+ + L+ + IE+S+ L ++ ++KL + +
Sbjct: 714 -------RAKTQHELERLEKLREETERSQKNIEESKIELMLWKESLDKLKGEMEEDKHVV 766
Query: 1796 FCSLNSRFYSLIHKVDNSGETLRAFVKNIQ---NQVAVSQEQHIE-----HQCKEELEGH 1951
+N + E L ++ ++ ++ +S+E+ E ++ + EL+
Sbjct: 767 IMQMN--------EAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQ 818
Query: 1952 IADLVLNDFSNDILSWSRRKEEA-----VVHDDEFDAERIALLNELKSLHQDLELLKAEE 2116
A++ D+ + ++ KEEA VH+ E ++ +E + E L+ +
Sbjct: 819 HAEM--EDWFRVV---NKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRD 873
Query: 2117 AVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLY 2296
++ + + K I Q +++ + E +Q + L + F E + E L
Sbjct: 874 EIQKKAEELEQINKEIQRARQELEKMRYFEKESLQ---KMLEDTQQERVFVEQVRSELLK 930
Query: 2297 TTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYEL 2476
+ K + +E K+L + + D R + E + +QS
Sbjct: 931 NKADQDKCLFEMDSERKELEQMRFQVENEKKDLEQRRY--EMMRYDVEQS---------A 979
Query: 2477 ELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEV 2656
++QR+ EE+ +K L+ + ++ I E+ NK L E
Sbjct: 980 QVQRQKEELEKIKSQLVIDTESMNRSRELARQDREKAELLIVEIQEQREDVNKRLE-ETK 1038
Query: 2657 QRYKMLCVLKEELQSKIDSLLK-------------EIKEKDSNSKVLAEKLSDALKKSAD 2797
QR + L +L+++++++ + L K E+KE+ + + E+L D +K D
Sbjct: 1039 QREEALRLLRKDMENEREDLEKIRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKG-D 1097
Query: 2798 HAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKE---FSLSLATKEQET 2968
+RE + H + E I E M ++ + VE+ ++KE + A E
Sbjct: 1098 QEEREK--INH--EKEEMIRKMEAMKREMGEI-EDMKVELTKQKENIDMKMEHARLEMTN 1152
Query: 2969 VNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKI 3148
+ + L + ED + + E ++ + + K KE+ E ++ L E EK+
Sbjct: 1153 LEMMKADLLRQKEDIENQMLAAKSERQQMEVMRTEILKQKEDVER---KMELAKAEMEKM 1209
Query: 3149 EEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXX 3328
+ K + + +E EE + + +++ ++ E E K+L
Sbjct: 1210 QHVKDEIQKQRKELEERMQKTKREIGEMELMKREMEGKKKELDQRMKLTMRKKEEMERLK 1269
Query: 3329 XXXXXISSNLDSMQLELRNYN---EELKNEIEKKSTDIDLLIKE------KEELNERLAY 3481
+++ ++E E++K EI++ + +L ++E KE++N +
Sbjct: 1270 MEIQRAKDDMEFKRVETERQKYEMEQVKAEIQRAREEFELRVEERDLEEEKEQMNLTIIN 1329
Query: 3482 TQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEK-------------YRDLLNSL 3622
+ +E ++ + F+ E + + SQ T +Q E R++L L
Sbjct: 1330 LIQQIEATREMVHKTKFQFENR---MAGSQMGTADQEEMNAEMQRLILEIEHIREMLRGL 1386
Query: 3623 TEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLK 3763
E K+ EE++ + +++ E ++ +EK++ + L+
Sbjct: 1387 KGEVEQNKEIMKRDREEIRLLKIEVQRRRREIEYREEKIMREQDELE 1433
Score = 84.0 bits (206), Expect = 5e-13
Identities = 228/1214 (18%), Positives = 473/1214 (38%), Gaps = 129/1214 (10%)
Frame = +2
Query: 527 VSAQEEEFKEALAAKDSENFLLNKKIEDLNHK---IWSLEETLQYKE---------EVIL 670
+ ++E+ ++ L A +EN LN++ + L+ K + S + L+YK+ +V
Sbjct: 1591 LQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSEKSKLEYKKPLEIKQVDAQVQT 1650
Query: 671 SSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASR----DNEMMHMVLEKDNIIL--- 829
E SE D L I E D +Q + +Q+L ++ + +M + L +D + L
Sbjct: 1651 ELMEDASEYDMALS--IEELDKQRQFLEYFKQELLAQKCTMERQMAEIELSRDELSLREA 1708
Query: 830 ----------SLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELG 979
+ Q+ELQ Q + +DE+E K E++K V+ TQI E
Sbjct: 1709 TLQTATQTTADMELQLELQKQELEQT----KDEME--RTKLEVQKGWVDL--QTQIAESR 1760
Query: 980 EEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAE-- 1153
E+ +++R+E K +D + ++ + ++ + +A+ L TL + N + +
Sbjct: 1761 EKEEMVRIELEKARDVLNRIRQDVETEKQTMEAD---LKFTLAKEFENLEAQRKMMEDEK 1817
Query: 1154 -IYENTFRELGDQ---ISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXX 1321
EN EL + I + +++M+ + +++ A ++ E K +
Sbjct: 1818 RALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERS 1877
Query: 1322 XXXXXXXTLKASMEMQCSKLK-----------------DELEEERGKISENLERISKLQK 1450
L+ E+ +++K DE+E E+ KI + ++Q
Sbjct: 1878 REIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQT 1937
Query: 1451 -MNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMA-----------------FG 1576
+N + E QN++ V +M
Sbjct: 1938 DLNRQQKEMQDIQNAVFMEKSELKKSQDEIAEQLKQVGDMMQFTQNEKDNLDRERAAIIE 1997
Query: 1577 SKLEELTDQINIFNSVID-----KKEA------------EVSGHLDTISSLQTVLSNQKF 1705
KL+ D ++ N ++ KKE + + + ++ L +K
Sbjct: 1998 QKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKE 2057
Query: 1706 EIE-----------KSQKVLQSFESHIEKLVNDSLHE---VDSAFCSL---NSRFYSLIH 1834
E++ K + VLQ+ EKL D+L E ++ A L ++
Sbjct: 2058 EMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAE 2117
Query: 1835 KVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSN--DILSWSRR 2008
+ E + I+ Q ++ + Q + + + V D N D+ ++
Sbjct: 2118 ETKRKREDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQK 2177
Query: 2009 KEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQ--- 2179
+ + + E +R L+E++ + D E + E L + FS+
Sbjct: 2178 ERQYMDRLVEEIEKRTKALDEMQ-MEVDKERQEVESKRDELEQETSKLREDEDEFSRQKE 2236
Query: 2180 ---LIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKK 2350
+IQ E+ +++ +S + + T F + L +E K + + K
Sbjct: 2237 KNNIIQAEIQKESDNLELQSENISKERT--IFELEKEHLGLRENEAEYKQKQIDELQNKL 2294
Query: 2351 LLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLN 2530
+ + E A R + +++ A ++ E+E R+ E + ++ +N
Sbjct: 2295 RMEKVQVEQMQADKDQQRKKAEYVKTARGRETTALEEQRQEMESLREEYENVEKQKKHVN 2354
Query: 2531 EKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYK-MLCVLKEELQSKI 2707
E+ L + + + EN E +++YK L E+LQ +
Sbjct: 2355 EQKEL-----------------FESRMKSLEMEN-----EAMKKYKEKLDKEYEDLQFQR 2392
Query: 2708 DSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDR-------E 2866
KEI++ + ++ AE + + KK + + + ++ + + + ++ E
Sbjct: 2393 QLFEKEIQQMRTELQIEAENI-ERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDE 2451
Query: 2867 IMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLC--LVGE 3040
+ + +D+ VE + ++L ++E+ +K+ K+ E++ + L +
Sbjct: 2452 VRKKINADLSE---VEKQKSALVQMNLKISQEESYVKKEKDRLKLQENEQNMQMSQLNAK 2508
Query: 3041 ENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNK 3220
+N+ +RQ A +EK K E EN R+ E+EK+E + + Q E++N+++ K
Sbjct: 2509 QNELDERQ-AEMEKQKRELENVMDRL-----EKEKVE-----ITKEKQRVNEMQNEVKRK 2557
Query: 3221 HSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEE- 3397
++ +D ++ QE L +Q I ++ + + EL E+
Sbjct: 2558 NASVDLIK--QEVLREQ----------------------DHIENSREILNRELEKIKEKK 2593
Query: 3398 --LKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAV---LVEKLFEGEQKILLLE 3562
L E E +++ KE + L + A QK E E + E+ ++ L+
Sbjct: 2594 TILAEEFEALDDKKEMIGKEMQRLGKMKAELQKEAEDTEKQRRDIDNDRRNNEEMVIKLQ 2653
Query: 3563 SSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKER-DLEVAMTETKFLKEKL 3739
+ + T++ RD E + ++KQ L + + KER DLE TE K L+++L
Sbjct: 2654 NEKKDIETSTDRIRD-----EEANLRVQKQRLESDRDTLEKERFDLEKTKTEMKDLEKQL 2708
Query: 3740 LVSDENLKEKDLQL 3781
+ ++ ++QL
Sbjct: 2709 ---ESQSRQHEIQL 2719
Score = 83.2 bits (204), Expect = 8e-13
Identities = 212/1227 (17%), Positives = 466/1227 (37%), Gaps = 63/1227 (5%)
Frame = +2
Query: 320 KIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGLYVSNV 499
+I L+ + DT N + +L +D + ++++ +++ + + L +
Sbjct: 7810 QIRAELQNKQRDMDDTTNIMMKEKAELARDLENLQNEKDELQKSRENIQKLMKELQEERL 7869
Query: 500 VSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSH 679
+ LN + ++F E + K N ++++ +I + L +E+I
Sbjct: 7870 KTSEALN----KERQQFTEEIKLK-------NDSLDEIQAEIDRQKRALVTDKEIITKQM 7918
Query: 680 ETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMV--LEKD-NIILSLHKQIE 850
+ + + + E D+ + Q + L E++ LE++ + +L + +E
Sbjct: 7919 MDLQKTQDVRRQS-DESDIARANLQRERESLDQLSVEILKQKQDLERERDELLEQWRLVE 7977
Query: 851 LQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEI 1030
Q + +++ + + ++++ E+I KQ+ + + +L +L L K
Sbjct: 7978 TQKMDNENVKQLKTELLDEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNLQK----- 8032
Query: 1031 QSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRND 1210
Q ++DE +A++ ++ L+ + ++E +YE + ++ +++
Sbjct: 8033 QGIQDE--------RAQLERMKGELQ--MKADDIERKMQEILYEK------QKYAERKSE 8076
Query: 1211 MYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDE 1390
Y +Y+D + + L+ E + E K +E+ ++ + E
Sbjct: 8077 NYKIQTYLDEANAEVQKLNKELERYDENLE----------------KCKLELDKARAETE 8120
Query: 1391 LEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMA 1570
++ KI E + LQK + +
Sbjct: 8121 RVKQGAKIPETQQIEQSLQKERDYI----------------------------------- 8145
Query: 1571 FGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESH 1750
E++ + I+K +AE+ + +Q + QK E+ K QK+ E
Sbjct: 8146 -----EDIRRNLFKKEEAIEKDKAEIRLRHQELDLIQAKVVKQKEEMVK-QKIESEREIQ 8199
Query: 1751 IEKL-VNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQ 1927
EK + S E++ + L D + + R V N QVA +
Sbjct: 8200 QEKKKLQRSEEELEDKMQKIKREMIELKLLQDET-DGKRKDVDNKMRQVA---------R 8249
Query: 1928 CKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLK 2107
++ELE AD+ + S + +++ + + ERI ++ + H
Sbjct: 8250 KRDELEKMKADV-------ESASKKLEVDRVMLNTERDELERIKTESQRATEHMQSH--- 8299
Query: 2108 AEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPE 2287
AEE L V+T+ +LIQE + K R + E
Sbjct: 8300 AEERAGDLGEKEPVNTR----IQRLIQEAEKASKMAWSTKHEPEMRMQREVSVEEESVER 8355
Query: 2288 DLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKRE 2467
+ + I+E E + A S L N E L K++ +
Sbjct: 8356 QDMSANMQRMILEIEHARETLRGMKDEVQAARKERSELENMKLEFLT--MKKNMEKTYEQ 8413
Query: 2468 YELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPV 2647
E+Q++ ++I K LL E+N L + +K+L EN+LL
Sbjct: 8414 QNDEIQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMALDK----QKLLAENELLER 8469
Query: 2648 EEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLK 2827
E+ K++ E L+S + +E A + + A ++ ++ ++ L
Sbjct: 8470 EKADVIKII----ENLESLREEATRE----------RATETAQATRRDSEELMQKMEALS 8515
Query: 2828 HIADLEAGITDREIMTSVCSDVLTALFVEMVREK-EFSLSLATKEQETVNQKQMSLRKML 3004
+ D + ++ + D L L ++++++ E + A +Q+ + ++ +
Sbjct: 8516 -MEDFQEASKNQMVELKRQIDKLIELKADLLQQQTELKKTKADLKQQMDDLEKTRSEILK 8574
Query: 3005 EDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEE----REKIEEQKRVLD 3172
+KD ++K + ++ +++ K++ E ++ L+ + R +I +K+ LD
Sbjct: 8575 HEKDT-------DSKTRELELIEIQRQKDDLETRIQKLTLEKRDLEVLRSEIVLEKKDLD 8627
Query: 3173 QALQ-------ECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXX 3331
Q ++ E E++++DI N +I+ R+E E L ++
Sbjct: 8628 QKMKQVIRKRDEMEKIRSDIANATEEINRERQELEILRNNVQ-SARHDFELLLERTANLE 8686
Query: 3332 XXXXISSNLDSMQLE-------LRNYNEELKNEIEKKSTDIDLLIKEKEELN-------- 3466
+++++ + LE +RN E++ +EK +ID K E+
Sbjct: 8687 DEESAATDIERLVLEVVKIREMVRNLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDIGQ 8746
Query: 3467 ------------ERLAYTQKAMEQKEAVLVEKLFEGE----------QKILLLESSQSAT 3580
E+ ++ +E+ A L EK E E +++ L+ +
Sbjct: 8747 IRENLGGLGEEIEKTRRDKRELEKMRAELAEKQQEQESMREMLHKEREELEQLKDEINRE 8806
Query: 3581 REQTEKYRDLLNSLTE-----EHADL---KKQFLSATEELQSKERDLEVAMTETKFLKEK 3736
+E E R+L+ ++ + E D+ K++ S TEEL +K+RDL+ ++ + L++
Sbjct: 8807 KEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQT 8866
Query: 3737 L--LVSDENLKEKDLQLRAFEIANSEK 3811
+ + K +L+ FE+ E+
Sbjct: 8867 IEEINIQHGKKRAELEGIGFELKKGEQ 8893
Score = 73.9 bits (180), Expect = 5e-10
Identities = 215/1271 (16%), Positives = 497/1271 (39%), Gaps = 103/1271 (8%)
Frame = +2
Query: 296 DTRKSLETKI---AETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLD 466
+ K ++T + A+ +E++++ ++ + ++ + L+E+I+ +D++D
Sbjct: 7153 EAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIKKKRDIID 7212
Query: 467 TVESGLYVSNVVSDAVLNGVVSAQEEEFKE------ALAAKDSENFLLNKKIEDLNHKIW 628
+ + ++ + + A+ + FK+ ALA + L K ++++
Sbjct: 7213 ESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQQKRNALEKMSKEISRDRM 7272
Query: 629 SLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVL 808
LE+ K+E+ L+ E +R+ D QR QE + L S +
Sbjct: 7273 KLEDE---KKEIQLAREEL----ERMHGDM--------QRQQEAKDHLLSG--------I 7309
Query: 809 EKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEH 988
++++ +I LQ R+ EI D + + ++V Q+ E+ +
Sbjct: 7310 TDESLLKKSEAEIVLQPSQVDKAKPARKTEISDSD---------KQPVFVQQMPEM-DLK 7359
Query: 989 DLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESL--FTAEIYE 1162
D L+ + + ++ +KD + K LE+ ++ ++ L AE+ +
Sbjct: 7360 DALKKDFESEKLDLPKVKDVLPQDQQMK----------LEQKLIEDEMDKLKQMRAELQK 7409
Query: 1163 NTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXX 1342
DQI + + DM ++ +D +A+R+ +L E+
Sbjct: 7410 EA-----DQIEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINIQ------------ 7452
Query: 1343 TLKASMEMQCSKLKDELEEERGKISENLERI-SKLQKMNNELAERSKSQNSIXXXXXXXX 1519
K + + Q + + E + ERI +++ + N ELA++ +
Sbjct: 7453 --KVNQQKQATAFQME--------KTDFERIKTEIDQANKELADQQE------------- 7489
Query: 1520 XXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQ 1699
K ++ ++ +++ A +S ++TI++ LS++
Sbjct: 7490 --------------------KNKKTITEMQKERETLEEMRANISKQVETITNENKSLSSR 7529
Query: 1700 KFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYS---LIHKVDNSGETLRAF 1870
+ E+ K Q+ + + +++L N + E+ C L+ R L +VD+ + +
Sbjct: 7530 ESELAKLQEDILQQQQEMDELKNTIMMEM----CQLDQRQSDIDLLQKEVDDLMDFTKTE 7585
Query: 1871 VKNIQNQ--VAVSQEQHIEHQCKE-ELEGHIAD---LVLNDFSNDILSWSRRKEEAVVHD 2032
+ N++ + ++Q ++I+ ++E + L LN+ D++ + +E +
Sbjct: 7586 MANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNE-EKDLIE--KERELLTKNL 7642
Query: 2033 DEFDAERIALLNELKSLHQDLELLKAEEA-VKSLSNNVGVSTKGIHYFSQLIQEGK---- 2197
D D +++ + EL++L + E +K E+ ++ + ++ G FS+ ++ +
Sbjct: 7643 DHTDKDKMDMKRELENLKVEKETIKNEKKELEKMKISLQRKAIGFKEFSEKTKDERPIVE 7702
Query: 2198 ----------DGEASDVQGKSRALRRHSTGQAFREPPKPEDLYT-------------TYS 2308
D +GK R T + R+ EDL+ Y
Sbjct: 7703 EMAAQFTRQLDISERPAEGKFIEERLDQTEKKRRKTYYTEDLFQEEKTDLQKTKEEINYD 7762
Query: 2309 EGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQR 2488
+I K+ + T++ + KE++ + + + ELQ
Sbjct: 7763 REEIYRQRTELNKEKETLKQMHTSNLKEIENIEKEKEKIQRTWNEL-----DQIRAELQN 7817
Query: 2489 KTEEIYDLKRLLLNEKNGL--HAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQR 2662
K ++ D +++ EK L E K K LQE +L E + +
Sbjct: 7818 KQRDMDDTTNIMMKEKAELARDLENLQNEKDELQKSRENIQKLMKELQEERLKTSEALNK 7877
Query: 2663 YKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLA-------------EKLSDALKKSAD-- 2797
+ EE++ K DSL + E D + L +K D ++S +
Sbjct: 7878 ERQQ--FTEEIKLKNDSLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDVRRQSDESD 7935
Query: 2798 ------HAQRES------HLLKHIADLEAGITD-----REIMTS-VCSDVLTALFVEMVR 2923
+RES +LK DLE + R + T + ++ + L E++
Sbjct: 7936 IARANLQRERESLDQLSVEILKQKQDLERERDELLEQWRLVETQKMDNENVKQLKTELLD 7995
Query: 2924 EKEFSLSLATKEQET---VNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEE 3094
EKE + + + ++ + + +++L K LE+ + + +E + +R L+ ++
Sbjct: 7996 EKESTEKIRKQLEQDKAYMEENKLNLHKELEELNLQKQGIQDERAQLERMKGELQMKADD 8055
Query: 3095 TENNPGRVFLQSEE-REKIEEQKRV---LDQALQECEELKNDIQNKHSDIDSLREEQEKL 3262
E + + ++ E+ E ++ LD+A E ++L +++ +++ + E +K
Sbjct: 8056 IERKMQEILYEKQKYAERKSENYKIQTYLDEANAEVQKLNKELERYDENLEKCKLELDKA 8115
Query: 3263 NKQLR-----CMXXXXXXXXXXXXXXXXXXXXISSNL-------DSMQLELRNYNEELKN 3406
+ I NL + + E+R ++EL
Sbjct: 8116 RAETERVKQGAKIPETQQIEQSLQKERDYIEDIRRNLFKKEEAIEKDKAEIRLRHQELDL 8175
Query: 3407 EIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATRE 3586
K + ++K+K E + +K +++ E L +K+ + +++++ L+ Q T
Sbjct: 8176 IQAKVVKQKEEMVKQKIESEREIQQEKKKLQRSEEELEDKMQKIKREMIELKLLQDETDG 8235
Query: 3587 QTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKE 3766
+ + + + + + +L+K + A E SK+ +++ M T+ + + + ++
Sbjct: 8236 KRKDVDNKMRQVARKRDELEK--MKADVESASKKLEVDRVMLNTERDELERIKTESQRAT 8293
Query: 3767 KDLQLRAFEIA 3799
+ +Q A E A
Sbjct: 8294 EHMQSHAEERA 8304
Score = 70.9 bits (172), Expect = 4e-09
Identities = 202/1162 (17%), Positives = 457/1162 (39%), Gaps = 73/1162 (6%)
Frame = +2
Query: 527 VSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVI------------- 667
+ EEF+ + +D L ++ E +N I +L + ++ E++
Sbjct: 1300 IQRAREEFELRVEERD-----LEEEKEQMNLTIINLIQQIEATREMVHKTKFQFENRMAG 1354
Query: 668 -----LSSHETISERDRLLKDFIHEKDLMQQRAQETEQ--KLASRDNEMMHMVLEKDNII 826
E +E RL+ + H +++++ E EQ ++ RD E + ++ + +
Sbjct: 1355 SQMGTADQEEMNAEMQRLILEIEHIREMLRGLKGEVEQNKEIMKRDREEIRLLKIE---V 1411
Query: 827 LSLHKQIELQSQNTQSLDCFRRDEIE-----DQNIKEEIEKQIVETIYVTQIQELGEEHD 991
++IE + + +DE+E Q +EE+E+++ E I +E+D
Sbjct: 1412 QRRRREIEYREEKIMR----EQDELELMSKMGQRQREELEERLEEVI---------KEND 1458
Query: 992 LLRLESAKYQDEIQSLKDECHAKE-MSKQAEISKLSHTLEESIMNSNLESLFTAE----- 1153
R+E + +D +LKD AKE + +Q E+ + + E T E
Sbjct: 1459 --RVEQMR-EDVNNALKDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAIK 1515
Query: 1154 IYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXX 1333
Y + EL I + R ++ I ++ + + ++
Sbjct: 1516 SYRASDLELSASIQKERQELEHYKEIILKEKHELNKIKEDVKAVKNDAEERMIKLHEEEK 1575
Query: 1334 XXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXX 1513
T + S++ +L+ E E+ N + + + N +L ER + +
Sbjct: 1576 EMKTKRVSLQNWERQLQTEKEK-------NQKGLDAIWNENQQLNERKQQLDIKELHLQS 1628
Query: 1514 XXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSV--IDKKEAEVSGHLDTISSLQTV 1687
V+ ++L E + ++ S+ +DK+ + + + +
Sbjct: 1629 EKSKLEYKKPLEIKQVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCT 1688
Query: 1688 LSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRA 1867
+ Q EIE S+ L E+ ++ + L + L D T
Sbjct: 1689 MERQMAEIELSRDELSLREATLQTATQTTA----DMELQLELQKQELEQTKDEMERTKLE 1744
Query: 1868 FVK---NIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHD-- 2032
K ++Q Q+A S+E+ E + ELE A VLN D+ + + E +
Sbjct: 1745 VQKGWVDLQTQIAESREK--EEMVRIELEK--ARDVLNRIRQDVETEKQTMEADLKFTLA 1800
Query: 2033 ---DEFDAERIALLNELKSL-HQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQ---E 2191
+ +A+R + +E ++L + EL + ++ +N+ + + +++ ++ E
Sbjct: 1801 KEFENLEAQRKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWE 1860
Query: 2192 GKDGEASDVQG----KSRALR-----RHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEE 2344
+ + D+Q +SR ++ R + D+ SE + E
Sbjct: 1861 ELEKKRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIEN 1920
Query: 2345 KKLLAILAFETADASDSPLRNWPKEQ--LLGHFKQSFAGLKREYELELQRKTEEIYDLKR 2518
+K + + L KE + + LK+ + E+ + +++ D+ +
Sbjct: 1921 EKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQD-EIAEQLKQVGDMMQ 1979
Query: 2519 LLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQ 2698
NEK+ L ++T + L+ KL+ E + ++L E+ +
Sbjct: 1980 FTQNEKDNLDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLL----EDCR 2035
Query: 2699 SKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDR-EIMT 2875
SL++++++ + K+ E+ + ++ E L+ + A T++ I T
Sbjct: 2036 I---SLMRDMQDLEQ-MKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDT 2091
Query: 2876 SVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEH 3055
L VE+ +E++ +++A E +K+ + K+ +K + +
Sbjct: 2092 LAEKQKLEDAAVELQKERDEIMNIA----EETKRKREDVDKIRVGIEKQEITFKDLKADL 2147
Query: 3056 KRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECE-------ELKNDIQ 3214
+++ AI+E ++ + + V + +I+++++ +D+ ++E E E++ ++
Sbjct: 2148 QKEAAIVENQRQAVQKDIQNV---KDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVD 2204
Query: 3215 NKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNE 3394
+ +++S R+E E+ +LR I D+++L+ N ++
Sbjct: 2205 KERQEVESKRDELEQETSKLR---EDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISK 2261
Query: 3395 EL------KNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILL 3556
E K + + + + K+ +EL +L + +EQ +A ++ +K
Sbjct: 2262 ERTIFELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQ----RKKAEY 2317
Query: 3557 LESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEE---LQSKERDLEVAMTETKFL 3727
+++++ E+ R + SL EE+ +++KQ E+ +S+ + LE+ K
Sbjct: 2318 VKTARGRETTALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKY 2377
Query: 3728 KEKLLVSDENLKEKDLQLRAFE 3793
KEKL D+ ++ Q + FE
Sbjct: 2378 KEKL---DKEYEDLQFQRQLFE 2396
Score = 63.5 bits (153), Expect = 7e-07
Identities = 89/436 (20%), Positives = 190/436 (43%), Gaps = 38/436 (8%)
Frame = +2
Query: 2588 VAEITGKFEKVLQENKLLPVEEVQRYKMLCVLK----EELQSKIDSLLKE--------IK 2731
V ++ +QE + + +E+V R K + ++ E+ +S I ++E +K
Sbjct: 14928 VTKLEDTLTSEVQEMRDMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEETLK 14987
Query: 2732 EKDSNSKVLAEKLSDA--LKKSADHAQRESHLL-----KHIADLEAGIT----DREIMTS 2878
EK N + L + L D L + D +E + ++IA LE I D+E +
Sbjct: 14988 EKSRNEETLLQLLHDKDDLSNTLDEKSKEIENITVTFKRNIAQLETTIAMMKKDKE---N 15044
Query: 2879 VCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHK 3058
+ +++L E RE + + E+E ++K ++ + LED +E K+
Sbjct: 15045 IENELLQLKQTEQEREIQRGTDDTSNERENYDEK-VTYKTELEDS--------KEKKKPD 15095
Query: 3059 RQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHS---D 3229
R + L+ ++ G Q+ E K+++ ++ D Q+ EEL ++++NK +
Sbjct: 15096 RDSS-LKLTDADSAKTDGEREAQTLET-KVQDVLQLTDYTTQDQEELHDEMENKMKIILE 15153
Query: 3230 IDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNE----- 3394
++ +++ +KL ++ R + S + S+ E+ + +
Sbjct: 15154 LNEAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEM 15213
Query: 3395 ---ELKNEIEKKST----DIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKIL 3553
E+K +I+ +S + D+ I++ +E E + K E++ + K + +
Sbjct: 15214 QQIEIKMQIQTRSVATQWETDVQIQQGQEATETTGHITKKSEEEISAKKTK----QPTVT 15269
Query: 3554 LLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKE 3733
LE + ++ + ++ RD LN E+ A +K ++L+ + D++ M E + E
Sbjct: 15270 KLEDTLTS---EVQEMRDSLNKEMEDVARMKTIMKMEKDQLEQAKSDIQTQMEEFERNME 15326
Query: 3734 KLLVSDENLKEKDLQL 3781
+ + +EK LQL
Sbjct: 15327 EAMEEKSRNEEKLLQL 15342
>ref|XP_001312904.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121894768|gb|EAX99974.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 3748
Score = 135 bits (341), Expect = 1e-28
Identities = 260/1211 (21%), Positives = 505/1211 (41%), Gaps = 97/1211 (8%)
Frame = +2
Query: 428 LLEDIRNTKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIE 607
L E +++ D + + L + +A N + + E E KD + + +++
Sbjct: 527 LNEQLKSKMDEMVKADQELQSAKDEHEAKKNELKAEIESVSDEISKLKDELEVIPDFEVD 586
Query: 608 DLNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDN 787
DL + L E L+ KEE+ E I D L I KD +Q+ + + K++ N
Sbjct: 587 DLKDQ---LNELLKEKEEL---EKEKIKNNDELNSSIIMLKDEIQKE-KANKDKISEEKN 639
Query: 788 EMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQN--IKEEIE--KQIVETIY 955
+ + ++ +S+ LD + DEIE++N + EE+E K V+
Sbjct: 640 KRDKELNDE-------------KSKLQDELDSLQLDEIENENDQLFEEVEDLKSKVDDAK 686
Query: 956 VTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAE-ISKLSHTLEESIMNSNL 1132
+ ++ ++ D L+ + +K + + + L+ + KE S + E +SK L+E + N N
Sbjct: 687 ILY-NDMVDKIDDLKQQRSKVEQKYKDLEKQ--NKEKSDEIEKVSKEISELKEKLDNLNQ 743
Query: 1133 ESLFTAEIYENTFR---------ELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKL 1285
T E+++ + ++I + N + + ++++ I+ ++ E +
Sbjct: 744 FKDNTPELHQKVDAMNEQIVKKSQENEKIQEEMNKLNEELQHLENEMEEIEVVNDERETI 803
Query: 1286 QE------QXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQ 1447
QE Q L E K D++E + E +RI LQ
Sbjct: 804 QEKIDNIKQQIEEKKKSNEEIQDIMNLLIEAENDAQKELDDIEIVEAQSEEIRQRIQTLQ 863
Query: 1448 -------KMNNELAERS-KSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQ 1603
K+NNEL E++ K Q + + + KL+E+ +Q
Sbjct: 864 DNLQDRKKLNNELTEQNNKLQKELKDLQNELDQTELVNDD------SESLNKKLDEIKEQ 917
Query: 1604 INIFNSVID-------------KKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFE 1744
IN S + +K A+ ++ I L Q E++K Q
Sbjct: 918 INERKSQNENNTEQNEKLIEEIEKFAKELDEIEIIEDKSDKLQAQISELQKQIDEKQKNN 977
Query: 1745 SHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEH 1924
+K ND HE+ L+S + V N+ + L++ ++N+ ++ ++ + +
Sbjct: 978 EQTDKSNNDLEHELQITKQKLDS-----MSSVKNNSDYLKSEIENVNKEIEKIRDTN--N 1030
Query: 1925 QCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIA---LLNEL-KSLHQD 2092
+ K+EL+ +L + DI S +E + +E +R+A ++EL + LH+D
Sbjct: 1031 KLKQELQDKNKEL---EEMTDIADNSEELKEKIDSVNEEITKRVANNTTIDELIRHLHED 1087
Query: 2093 LELLKAE-EAVKSLSNNVGVSTKGI-HYFSQLIQEGKDG-EASDVQGKSRALRRHSTGQA 2263
L+ +A+ +++ + +N K + +Q+ Q+ ++ E +D + + T +
Sbjct: 1088 LKNAEAKLQSIPHVDDNTDSLQKSLDEVLAQISQKQRENDELNDEISRLIQEKEEKTDEL 1147
Query: 2264 FREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETA----------------DASDS 2395
P+ SE + V+ E+KK +A E + SD
Sbjct: 1148 NNMETIPDKREEISSEIETVKSQIEEKKKNNEKIAEENKKLAEELENLRQTLSKMETSDQ 1207
Query: 2396 PLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXX 2575
PL N KE + KQ + ++E + EL+++ E+I D + +E +
Sbjct: 1208 PLENIQKE--IETTKQEISEKQKELD-ELKQELEQIKDEDQSKADEIS-------EEIEN 1257
Query: 2576 XXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKE------ELQSKIDSLLKEI--- 2728
+ E K E++ + N+ E ++ K L L+E E+ +I+ KEI
Sbjct: 1258 IKTQIDEKNKKNEEIAKNNEEKQSELDEKLKELQDLEEIKDETEEINQQIEETQKEIETK 1317
Query: 2729 KEKDSNSKVLAEKLSDALKKSADHAQR-ESHLLKHIADLEAGITDREIMTSVCSDVLTAL 2905
K++ N+ L E+L D LK+ + + E ++ K ++E +D + + +D+ A
Sbjct: 1318 KQQKENNNKLNEEL-DKLKQDLEQIENVEDNVEKLTEEIEKVKSDIDSKHQLNNDIKEAN 1376
Query: 2906 FVEMVREKEFSLSLATKEQETVNQKQMSLRKML-------EDKDKLLCLVGEENKEHKRQ 3064
E+V E+ SL ++ E V K +RK + E K C + E N+ ++
Sbjct: 1377 --EVVEEELNSLKEELEKIEPVEDKSDEIRKEIVKIQKEIETKKATNCGISESNELLNKE 1434
Query: 3065 IAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLR 3244
+ L+ EE +EE++ EE K ++ + EE K N + ++++
Sbjct: 1435 LNDLKNQLEEI----------AEEKDDSEEIKAEIENLHKSIEEKKEHNANTQQNNENMK 1484
Query: 3245 EEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISS-NLDSMQLELRN--YNEELKNEIE 3415
EE KL ++ + I N + ++ N NEEL N ++
Sbjct: 1485 EELSKLQEEFDQIEVVEDKAEEIHSEIEKLKSQIEEKNTTNNDIKEANDILNEELNN-LQ 1543
Query: 3416 KKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILL-LESSQ------- 3571
K+ +ID+ + EEL++++ QK +E+K++ E + G + IL L+S Q
Sbjct: 1544 KQYDEIDVEEDKSEELSQKVTDLQKLLEEKKS-QNETIKSGNENILKELQSLQNELDNIE 1602
Query: 3572 --SATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEK--- 3736
S++ E+ EK + L + + ++ EEL ++ +DLE + E +K+K
Sbjct: 1603 VVSSSSEEGEKKIEKLKQMISDKQKQNEETTKHNEELDNQIKDLENELNEIIPVKDKSND 1662
Query: 3737 LLVSDENLKEK 3769
L E +K+K
Sbjct: 1663 LQQQIEEIKDK 1673
Score = 124 bits (312), Expect = 2e-25
Identities = 240/1221 (19%), Positives = 503/1221 (41%), Gaps = 51/1221 (4%)
Frame = +2
Query: 314 ETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGL-YV 490
E K+ + + ++E + + +K++ D + P + L + + T E L +
Sbjct: 307 EEKLKKQIAKVESEKTKIEDEIKHLQED---EEPQIKKLKDRLDETTTKTQIAEKKLGEM 363
Query: 491 SNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVIL 670
+ D+ Q + D+EN N +++ +N++I ++ ++
Sbjct: 364 RKTIEDSRQKLAQRRQNLIERRKELTNDAEN--TNTELQSINNQIQEIDSEFNKLNGLVN 421
Query: 671 SSHETISERDRLLKDFI--HEKDLMQQRAQETEQKLASRD------NEMMHMVLEKDNII 826
S++ L++ + +KDL + ++ E+K ASR+ N+ + +++ N
Sbjct: 422 KVQSDHSKKKSALQEQLAQKQKDLNDLKRKQAEEK-ASREAEIAKINDQLQKTMKEYND- 479
Query: 827 LSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLE 1006
L+ + ++L+++ Q+ + E+E + K+ E V ++ +L E+ E
Sbjct: 480 LNQPQNVDLKNEIDQATKDLK--ELESRVNKKREELFGKNNQRVAELNKLNEQLKSKMDE 537
Query: 1007 SAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESL--FTAEIYENTFREL 1180
K E+QS KDE AK+ +AEI +S E S + LE + F + ++ EL
Sbjct: 538 MVKADQELQSAKDEHEAKKNELKAEIESVSD--EISKLKDELEVIPDFEVDDLKDQLNEL 595
Query: 1181 GDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASM 1360
+ +L + N D L S I L E K + K +
Sbjct: 596 LKEKEELEKEKIKNN---DELNSSIIMLKDEIQKEKAN------------------KDKI 634
Query: 1361 EMQCSKLKDELEEERGKISENLE--RISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXX 1534
+ +K EL +E+ K+ + L+ ++ +++ N++L E + S
Sbjct: 635 SEEKNKRDKELNDEKSKLQDELDSLQLDEIENENDQLFEEVEDLKS-KVDDAKILYNDMV 693
Query: 1535 XXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSN-----Q 1699
K ++L Q + I+K E+S + + +L N Q
Sbjct: 694 DKIDDLKQQRSKVEQKYKDLEKQNKEKSDEIEKVSKEISELKEKLDNLNQFKDNTPELHQ 753
Query: 1700 KFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKN 1879
K + Q V +S E+ + + + +++++ L + I V++ ET++ + N
Sbjct: 754 KVDAMNEQIVKKSQEN---EKIQEEMNKLNEELQHLENEMEE-IEVVNDERETIQEKIDN 809
Query: 1880 IQNQVAVSQEQHIEHQ--------CKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDD 2035
I+ Q+ ++ + E Q + + + + D+ + + ++ + R+ + D+
Sbjct: 810 IKQQIEEKKKSNEEIQDIMNLLIEAENDAQKELDDIEIVEAQSEEI----RQRIQTLQDN 865
Query: 2036 EFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASD 2215
D ++ L NEL + K ++ +K L N + T+ ++ S+ + + D E +
Sbjct: 866 LQDRKK--LNNELTEQNN-----KLQKELKDLQNELD-QTELVNDDSESLNKKLD-EIKE 916
Query: 2216 VQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDS 2395
+ ++ ++T Q + + E E +I+E + A S
Sbjct: 917 QINERKSQNENNTEQNEKLIEEIEKFAKELDEIEIIEDKS------------DKLQAQIS 964
Query: 2396 PLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXX 2575
L+ E+ + + + E+EL++ T++ D + N + L +
Sbjct: 965 ELQKQIDEKQKNNEQTDKSNNDLEHELQI---TKQKLDSMSSVKNNSDYLKS-------- 1013
Query: 2576 XXXXVAEITGKFEKVLQENKLLPVE------EVQRYKMLCVLKEELQSKIDSLLKEIKEK 2737
+ + + EK+ N L E E++ + EEL+ KIDS+ +EI ++
Sbjct: 1014 ---EIENVNKEIEKIRDTNNKLKQELQDKNKELEEMTDIADNSEELKEKIDSVNEEITKR 1070
Query: 2738 DSNSKVLAE---KLSDALKKSADHAQRESH-------LLKHIADLEAGITDREIMTSVCS 2887
+N+ + E L + LK + Q H L K + ++ A I+ ++ +
Sbjct: 1071 VANNTTIDELIRHLHEDLKNAEAKLQSIPHVDDNTDSLQKSLDEVLAQISQKQRENDELN 1130
Query: 2888 DVLTALFVEMVREKEFSLSLAT--KEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKR 3061
D ++ L E + + ++ T ++E ++ + +++ +E+K K + EENK+
Sbjct: 1131 DEISRLIQEKEEKTDELNNMETIPDKREEISSEIETVKSQIEEKKKNNEKIAEENKKLAE 1190
Query: 3062 QIAILEKL--KEETENNPGRVFLQSEE--REKIEEQKRVLDQALQECEELKNDIQNKHSD 3229
++ L + K ET + P + E +++I E+++ LD+ QE E++K++ Q+K
Sbjct: 1191 ELENLRQTLSKMETSDQPLENIQKEIETTKQEISEKQKELDELKQELEQIKDEDQSK--- 1247
Query: 3230 IDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNE 3409
D + EE E + Q+ + E+ NEE ++E
Sbjct: 1248 ADEISEEIENIKTQI-------------------------DEKNKKNEEIAKNNEEKQSE 1282
Query: 3410 IE---KKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSAT 3580
++ K+ D++ + E EE+N+++ TQK +E K ++ E K+
Sbjct: 1283 LDEKLKELQDLEEIKDETEEINQQIEETQKEIETK-----KQQKENNNKLNEELDKLKQD 1337
Query: 3581 REQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENL 3760
EQ E D + LTEE +K S + + EV E LKE+ L E +
Sbjct: 1338 LEQIENVEDNVEKLTEEIEKVKSDIDSKHQLNNDIKEANEVVEEELNSLKEE-LEKIEPV 1396
Query: 3761 KEKDLQLRAFEIANSEKQYQT 3823
++K ++R EI +K+ +T
Sbjct: 1397 EDKSDEIRK-EIVKIQKEIET 1416
Score = 118 bits (296), Expect = 2e-23
Identities = 260/1267 (20%), Positives = 522/1267 (41%), Gaps = 95/1267 (7%)
Frame = +2
Query: 293 LDTRKS--LETKIA-ETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLL 463
+++RKS LE +++ ET E+ LK DL Q + L E+I TK L
Sbjct: 1778 INSRKSNNLERQVSNETFEKQ-------LGQLKQELNDLPQTDDNSESLKEEIEETKKKL 1830
Query: 464 DTVESGLYVSNVVSDAVLNGVVSAQEE--EFKEALAAKDSENFLLNKK-------IEDLN 616
++ + ++ + ++ + E + + ++E + +K I DL
Sbjct: 1831 AMMKDEYQRMSDEDKSLTDELIRVESELNDLENQKNVLENETIVKAEKKMQNDNTIMDLR 1890
Query: 617 HKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMM 796
+KI +L+ LQ +E+ E I ++L K++ K + + +++++ +NE+
Sbjct: 1891 NKIDTLKAQLQQQEK----PQEDI---EKLKKEYQELKFQFDAKVSQNKEEVSHSENEL- 1942
Query: 797 HMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQEL 976
H + E + I + +Q ++ S +Q L + +I+DQN K E K+ +E + ++
Sbjct: 1943 HSLKEMYDKIEKVEQQ-QVDSLKSQILSV--KAQIDDQNKKNEEMKKQIEKL---TSEKS 1996
Query: 977 GEEHDLLRLESAKYQDEIQSLKDECH-----AKEMSKQAEISKLSHTLEESIMN-----S 1126
+++L + E+ DE+ L +E A E KQ E ++ +LEE +
Sbjct: 1997 DAQNELEKAENKVDPDELVRLSEEIEELKLEADEKKKQNE--EVRSSLEEELSKYKEILE 2054
Query: 1127 NLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXX 1306
NL+S ++I+ N ++ D+I++ + + + N + + + L NK E+
Sbjct: 2055 NLKSDNQSDIH-NQIDQIKDRINEKQQENEADNQKLQEIINNHKKLLENMNKEHEE---- 2109
Query: 1307 XXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQ 1486
++ +E + K E+++++ +I+E E++ + +K N + ++ + Q
Sbjct: 2110 -------------IQKQIEQEVDKNNKEIDQKQKEINEVKEKLQQAKKENED--DKVELQ 2154
Query: 1487 NSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTD----QINIFNSVIDKKEAEVSG 1654
I G ++E+L + +I++ IDKKE E
Sbjct: 2155 RQIDNC-----------------------GREIEKLQNAGDSEIDLLKQEIDKKEKE--- 2188
Query: 1655 HLDTISSLQTVLSNQKFEIEKSQKVLQSFES----HIEKLVND------SLHEVDSAFCS 1804
Q ++ EIE + LQ E + EKL N+ + + + +
Sbjct: 2189 -------RQQATEQKQHEIEMYKAKLQHKEQENAVNAEKLHNEIENLKKKIDSQEMEYKN 2241
Query: 1805 LNSRFYSLIHKV---------DNSGETLRAF-VKNIQNQVAVSQEQHIE---------HQ 1927
N ++ K+ +N E RA V+N++ Q+A ++Q+ ++
Sbjct: 2242 YNESLTKILDKLKVKLEEVEEENRNEDERAEEVENLKAQIASKRKQNDAENEKLSQEINK 2301
Query: 1928 CKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELL- 2104
KEEL+ + + + + K + V D + E+I L E+ L + E L
Sbjct: 2302 LKEELQNLQENTEIEEMKQTV---EDLKTQISVFGDP-EQEKIKLQKEIDELTEKTEKLA 2357
Query: 2105 -------KAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRH----- 2248
K E +++L N V ++ + + E +DGE + + L+
Sbjct: 2358 EADDENDKLREQIENLKN---VKSRDVEIID--LGEEEDGERQQLVEELNKLKEEYEQLQ 2412
Query: 2249 STGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLL 2428
+T + DL E K + LL L+ + + KE++
Sbjct: 2413 NTDDINDLKQEVIDLSKQIDEIKASNKDAQTKSDLLKELSQLNSQIENIIQEEEDKEEIR 2472
Query: 2429 GHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGK 2608
H ++ + L + E ++ E+ DLK+ L ++++ ++
Sbjct: 2473 SHIEEIKSLLDNKQSEEDEK---ELDDLKKQLEDKQSLIN-------------------- 2509
Query: 2609 FEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEK---DSNSKVLA---EKL 2770
K+ ++ KL E + K + ++L+ + D L E +E+ D K+L E+L
Sbjct: 2510 --KLKEDIKLTKEENEKAQKNI----DDLEQEFDDLNNEYEEESQFDEERKLLETEIERL 2563
Query: 2771 SDAL-KKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSL 2947
+ +K + ++ L K I DL E + S+ D + E ++
Sbjct: 2564 KQLISEKKTQNKEKTDKLFKEINDLT------EELNSLEDDSENKELQSQIDELNEQIN- 2616
Query: 2948 ATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQ 3127
+ KE+ Q + +L+K L+D + L + E+ +E+++ ++ LKEE ++N + Q
Sbjct: 2617 SVKEESNPQQTKENLQKELDDLNNKLQQMIEDEEENEKLKEEIDALKEELKDNKSQEENQ 2676
Query: 3128 SEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQE--------KLNKQLRCM 3283
+ + +I E + + Q E E +N ++++ S + + +E+E L K++ +
Sbjct: 2677 -QLKSQISELQEQIKQKQNEISETENSLKSQISQLQNELKEKESERGDKSNSLYKEIDSL 2735
Query: 3284 XXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEI----EKKSTDIDLLIKE 3451
+ +L EL NE +K++I EK +++ L +E
Sbjct: 2736 KEKINNQEIENKADSSQLSDLLKDLKKKLQELTEENETIKSKISEEKEKSKSEMAKLEEE 2795
Query: 3452 KEELNERLAYTQKAMEQKEAVLVEKLFEGEQKIL--LLESSQSATREQTEKYRDLLNSLT 3625
K+ LN+ L E KE + EGE L L + EQ +K LT
Sbjct: 2796 KKSLNKELENVNDD-EDKE------MLEGEVSSLKETLNLKKQINEEQKQKLSQEKEKLT 2848
Query: 3626 EE------HADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRA 3787
EE + DLKK+ EEL+ + D + + E + LK++ + +++ K+ L+
Sbjct: 2849 EELSQLNDNEDLKKEIEQKKEELEKLKNDSSL-LQELQDLKKQ--IEEKSEKQNPELLKQ 2905
Query: 3788 FEIANSE 3808
E E
Sbjct: 2906 IEDLKKE 2912
Score = 115 bits (288), Expect = 1e-22
Identities = 239/1263 (18%), Positives = 513/1263 (40%), Gaps = 90/1263 (7%)
Frame = +2
Query: 296 DTRKSLETKIAETLERMEIHEGDTANTLKN--------MNFDLGQDNPGVPGLLEDIRNT 451
+ R SLE ++++ E +E + D + + N +N ++ L E I N
Sbjct: 2037 EVRSSLEEELSKYKEILENLKSDNQSDIHNQIDQIKDRINEKQQENEADNQKLQEIINNH 2096
Query: 452 KDLLDT-----------VESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNK 598
K LL+ +E + +N D + + +E+ ++A + + L +
Sbjct: 2097 KKLLENMNKEHEEIQKQIEQEVDKNNKEIDQKQKEI-NEVKEKLQQAKKENEDDKVELQR 2155
Query: 599 KIEDLNHKIWSLEETLQYKEEVILSS-HETISERDRLLKDFIHEKDLMQQRAQETEQKLA 775
+I++ +I L+ + +++ + ER + + HE ++ + + Q EQ+ A
Sbjct: 2156 QIDNCGREIEKLQNAGDSEIDLLKQEIDKKEKERQQATEQKQHEIEMYKAKLQHKEQENA 2215
Query: 776 SRDNEMMHMVLEKDNIILSLHKQIELQSQN--------TQSLDCFR--RDEIEDQNIKEE 925
+ E +H N I +L K+I+ Q T+ LD + +E+E++N E+
Sbjct: 2216 V-NAEKLH------NEIENLKKKIDSQEMEYKNYNESLTKILDKLKVKLEEVEEENRNED 2268
Query: 926 IEKQIVETI---YVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAE----- 1081
+ VE + ++ ++ E++ L E K ++E+Q+L++ +EM + E
Sbjct: 2269 ERAEEVENLKAQIASKRKQNDAENEKLSQEINKLKEELQNLQENTEIEEMKQTVEDLKTQ 2328
Query: 1082 ISKLSHTLEESI--------MNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYID 1237
IS +E I + E L A+ + RE QI L+N + S++ I
Sbjct: 2329 ISVFGDPEQEKIKLQKEIDELTEKTEKLAEADDENDKLRE---QIENLKN-VKSRDVEII 2384
Query: 1238 SLASRIDF----LSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEM-------QCSKLK 1384
L D L E NKL+E+ + S ++ + ++ K
Sbjct: 2385 DLGEEEDGERQQLVEELNKLKEEYEQLQNTDDINDLKQEVIDLSKQIDEIKASNKDAQTK 2444
Query: 1385 DELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVN 1564
+L +E +++ +E I + ++ E+ + S+
Sbjct: 2445 SDLLKELSQLNSQIENIIQEEEDKEEIRSHIEEIKSLLDNKQSEEDEKELDDLKKQLEDK 2504
Query: 1565 MAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFE 1744
+ +KL+E N K ++ D +++ ++ + ++ +K+L++
Sbjct: 2505 QSLINKLKEDIKLTKEENEKAQKNIDDLEQEFDDLNNEY----EEESQFDEERKLLETEI 2560
Query: 1745 SHIEKLVND----SLHEVDSAFCSLNSRFYSLIHKVDNS-GETLRAFVKNIQNQVAVSQE 1909
+++L+++ + + D F +N L D+S + L++ + + Q+ +E
Sbjct: 2561 ERLKQLISEKKTQNKEKTDKLFKEINDLTEELNSLEDDSENKELQSQIDELNEQINSVKE 2620
Query: 1910 QHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALL-NELKSLH 2086
+ Q KE L+ L+D +N + +EE +E DA + L N+ + +
Sbjct: 2621 ESNPQQTKENLQKE-----LDDLNNKLQQMIEDEEENEKLKEEIDALKEELKDNKSQEEN 2675
Query: 2087 QDL--ELLKAEEAVKSLSNNVGVSTKGIH-YFSQLIQEGKDGEA------SDVQGKSRAL 2239
Q L ++ + +E +K N + + + SQL E K+ E+ + + + +L
Sbjct: 2676 QQLKSQISELQEQIKQKQNEISETENSLKSQISQLQNELKEKESERGDKSNSLYKEIDSL 2735
Query: 2240 RRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKE 2419
+ Q L + K TEE + + E + S S + +E
Sbjct: 2736 KEKINNQEIENKADSSQLSDLLKDLKKKLQELTEENETIKSKISEEKEKSKSEMAKLEEE 2795
Query: 2420 QLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEI 2599
K+ EL+ ++ + K +L E + L ++
Sbjct: 2796 -------------KKSLNKELENVNDD--EDKEMLEGEVSSLKETLNLKKQINEEQKQKL 2840
Query: 2600 TGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDA 2779
+ + EK+ +E L E LK+E++ K KE EK N L ++L D
Sbjct: 2841 SQEKEKLTEELSQLNDNED--------LKKEIEQK-----KEELEKLKNDSSLLQELQDL 2887
Query: 2780 LKKSADHAQRES-HLLKHIADLEAGITDREIMTSVCS---DVLTALFVEMVREKEFSLSL 2947
K+ + +++++ LLK I DL+ I+++E + + + + + ++V ++++ S
Sbjct: 2888 KKQIEEKSEKQNPELLKQIEDLKKEISEKESENDLITGEKNTVEQQYNKLVEQRKYLEST 2947
Query: 2948 ATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQ 3127
++ V+ + ++ ++ +E +E K+ I ++ +E+
Sbjct: 2948 MEAAKKKVSDLRQQCDELSMKNNQFRIDNEKEFQEIKKSIEEIKGQREQLAKK------H 3001
Query: 3128 SEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXX 3307
+E++ + E + Q L + ++ + + K+ ++ + EQEK
Sbjct: 3002 NEDKRRAREYNTLARQKLTDAQQKLDAEKAKNENLLKMMSEQEKT--------------- 3046
Query: 3308 XXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEI----EKKSTDIDLLIKEKEE---LN 3466
SNL+ +L N+EL+ ++ + I+ L K+KEE LN
Sbjct: 3047 -------------VSNLEKESEDLEQKNKELEQQMTSTGDFSQDKIEELRKKKEELQKLN 3093
Query: 3467 ERLAYTQKA-MEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDL------LNSLT 3625
+ L+ QK +EQ ++ EK+ + L S+++ +E TE + L ++ +
Sbjct: 3094 DELSQKQKQNIEQSNSLQNEKVTLSNEIESLKSSTEAMEKESTEMEKKLEEDKGIISEKS 3153
Query: 3626 EEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANS 3805
+E DL+K+ ++E Q K L+ + E + +K+ + +L +K L I+N+
Sbjct: 3154 KEKEDLEKK----SKEQQEKSDKLKQEVAELQEKAKKITTENTDLNDKITDLE-ISISNA 3208
Query: 3806 EKQ 3814
E++
Sbjct: 3209 ERR 3211
Score = 115 bits (287), Expect = 2e-22
Identities = 266/1318 (20%), Positives = 530/1318 (40%), Gaps = 150/1318 (11%)
Frame = +2
Query: 305 KSLETKIAETLERMEIHE---GDTANTLKNMNFDLGQDNPGV----PGLLEDIRNTKDLL 463
K L+ ++ ET + +I E G+ T+++ L Q + L D NT L
Sbjct: 340 KKLKDRLDETTTKTQIAEKKLGEMRKTIEDSRQKLAQRRQNLIERRKELTNDAENTNTEL 399
Query: 464 DTVESGLYVSNVVSDA-VLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEE 640
++ + + + S+ LNG+V+ + + + +A + K + DL K EE
Sbjct: 400 QSINN--QIQEIDSEFNKLNGLVNKVQSDHSKKKSALQEQLAQKQKDLNDLKRK--QAEE 455
Query: 641 TLQYKEEVILSSHE---TISERDRL-------LKDFIHE--KDL--MQQRAQETEQKLAS 778
+ E+ + + T+ E + L LK+ I + KDL ++ R + ++L
Sbjct: 456 KASREAEIAKINDQLQKTMKEYNDLNQPQNVDLKNEIDQATKDLKELESRVNKKREELFG 515
Query: 779 RDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDC---FRRDEI--EDQNIKEEIEK--- 934
++N+ + + + + + S ++ Q QS +++E+ E +++ +EI K
Sbjct: 516 KNNQRVAELNKLNEQLKSKMDEMVKADQELQSAKDEHEAKKNELKAEIESVSDEISKLKD 575
Query: 935 --QIVETIYVT----QIQELGEEHDLLRLESAKYQDEIQS----LKDECHAKEMSKQA-- 1078
+++ V Q+ EL +E + L E K DE+ S LKDE ++ +K
Sbjct: 576 ELEVIPDFEVDDLKDQLNELLKEKEELEKEKIKNNDELNSSIIMLKDEIQKEKANKDKIS 635
Query: 1079 -EISKLSHTL--EESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLAS 1249
E +K L E+S + L+SL EI EN +L +++ L++ + + +
Sbjct: 636 EEKNKRDKELNDEKSKLQDELDSLQLDEI-ENENDQLFEEVEDLKSKVDDAKILYNDMVD 694
Query: 1250 RIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLE 1429
+ID L + +K++++ +E Q + DE+E+ +ISE E
Sbjct: 695 KIDDLKQQRSKVEQKYK------------------DLEKQNKEKSDEIEKVSKEISELKE 736
Query: 1430 RISKLQK--------------MNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXX--VV 1561
++ L + MN ++ ++S+ I VV
Sbjct: 737 KLDNLNQFKDNTPELHQKVDAMNEQIVKKSQENEKIQEEMNKLNEELQHLENEMEEIEVV 796
Query: 1562 N---MAFGSKLEELTDQI-----------NIFNSVIDKKEAEVSGHLDTISSLQTVLSNQ 1699
N K++ + QI +I N +I+ E + LD I ++
Sbjct: 797 NDERETIQEKIDNIKQQIEEKKKSNEEIQDIMNLLIEA-ENDAQKELDDIEIVEAQSEEI 855
Query: 1700 KFEIEKSQKVLQSFE----------SHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNS 1849
+ I+ Q LQ + + ++K + D +E+D +N SL K+D
Sbjct: 856 RQRIQTLQDNLQDRKKLNNELTEQNNKLQKELKDLQNELDQTEL-VNDDSESLNKKLDEI 914
Query: 1850 GETLRAFVKNIQNQVAVSQE--QHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAV 2023
E + +N +++ + IE KE E I + + I ++ +E
Sbjct: 915 KEQINERKSQNENNTEQNEKLIEEIEKFAKELDEIEIIEDKSDKLQAQISELQKQIDEKQ 974
Query: 2024 VHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDG 2203
++++ D L +EL+ Q L+ + + VK+ S+ + + ++ + I++ +
Sbjct: 975 KNNEQTDKSNNDLEHELQITKQKLDSMSS---VKNNSDYLKSEIENVNKEIEKIRDTNNK 1031
Query: 2204 EASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETAD 2383
++Q K++ L T A E + + E + T +L+ L + +
Sbjct: 1032 LKQELQDKNKELEE-MTDIADNSEELKEKIDSVNEEITKRVANNTTIDELIRHLHEDLKN 1090
Query: 2384 ASDSPLRNWPKEQLLGHFKQSFAGLKREYELEL------QRKTEEIYDLKRLLLNEK--- 2536
A K Q + H + L++ + L QR+ +E+ D L+ EK
Sbjct: 1091 AE-------AKLQSIPHVDDNTDSLQKSLDEVLAQISQKQRENDELNDEISRLIQEKEEK 1143
Query: 2537 ----NGLHAXXXXXXXXXXXX------VAEITGKFEKVLQENKLLPVEEVQRYKMLCVLK 2686
N + + E EK+ +ENK L EE++ +
Sbjct: 1144 TDELNNMETIPDKREEISSEIETVKSQIEEKKKNNEKIAEENKKL-AEELENLRQTLSKM 1202
Query: 2687 EELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDRE 2866
E ++++ KEI ++ + ++EK +K D ++E +K +A E
Sbjct: 1203 ETSDQPLENIQKEI---ETTKQEISEK-----QKELDELKQELEQIKDEDQSKADEISEE 1254
Query: 2867 IMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEEN 3046
I ++ T + + + +E + + K+ E +++K L+ + E KD+ + ++
Sbjct: 1255 I-----ENIKTQIDEKNKKNEEIAKNNEEKQSE-LDEKLKELQDLEEIKDETE-EINQQI 1307
Query: 3047 KEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKH- 3223
+E +++I ++ KE + ++ E+IE + +++ +E E++K+DI +KH
Sbjct: 1308 EETQKEIETKKQQKENNNKLNEELDKLKQDLEQIENVEDNVEKLTEEIEKVKSDIDSKHQ 1367
Query: 3224 -------------SDIDSLREEQEK----------LNKQLRCMXXXXXXXXXXXXXXXXX 3334
+++SL+EE EK + K++ +
Sbjct: 1368 LNNDIKEANEVVEEELNSLKEELEKIEPVEDKSDEIRKEIVKIQKEIETKKATNCGISES 1427
Query: 3335 XXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAV 3514
++ L+ ++ +L EE K++ E+ +I+ L K EE E A TQ+ E +
Sbjct: 1428 NELLNKELNDLKNQLEEIAEE-KDDSEEIKAEIENLHKSIEEKKEHNANTQQNNENMKEE 1486
Query: 3515 LVEKLFEGEQKILLLESSQSATREQTEKYRDLLNS--------------LTEEHADLKKQ 3652
L KL E +I ++E + EK + + L EE +L+KQ
Sbjct: 1487 L-SKLQEEFDQIEVVEDKAEEIHSEIEKLKSQIEEKNTTNNDIKEANDILNEELNNLQKQ 1545
Query: 3653 F------LSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSE 3808
+ +EEL K DL+ + E K E + +EN+ K+LQ E+ N E
Sbjct: 1546 YDEIDVEEDKSEELSQKVTDLQKLLEEKKSQNETIKSGNENIL-KELQSLQNELDNIE 1602
Score = 112 bits (280), Expect = 1e-21
Identities = 209/1128 (18%), Positives = 443/1128 (39%), Gaps = 55/1128 (4%)
Frame = +2
Query: 251 DISVTSFIEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGL 430
D+ + E EDG K+ E E+++ D N LK DL + +
Sbjct: 2380 DVEIIDLGEEEDGERQQLVEELNKLKEEYEQLQ--NTDDINDLKQEVIDLSKQIDEIKAS 2437
Query: 431 LEDIRNTKDLLDTVES-GLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFL-----L 592
+D + DLL + + N++ + + + EE K L K SE L
Sbjct: 2438 NKDAQTKSDLLKELSQLNSQIENIIQEEEDKEEIRSHIEEIKSLLDNKQSEEDEKELDDL 2497
Query: 593 NKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKD----------FIHEKDLMQ 742
K++ED I L+E ++ +E + + I + ++ D F E+ L++
Sbjct: 2498 KKQLEDKQSLINKLKEDIKLTKEENEKAQKNIDDLEQEFDDLNNEYEEESQFDEERKLLE 2557
Query: 743 QRAQETEQ--------------KLASRDNEMMHMV--LEKDNIILSLHKQIELQSQNTQS 874
+ +Q KL N++ + LE D+ L QI+ ++ S
Sbjct: 2558 TEIERLKQLISEKKTQNKEKTDKLFKEINDLTEELNSLEDDSENKELQSQIDELNEQINS 2617
Query: 875 LDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECH 1054
+ ++E Q KE ++K++ + ++Q++ E+ + E+ K ++EI +LK+E
Sbjct: 2618 V----KEESNPQQTKENLQKELDDLN--NKLQQMIEDEE----ENEKLKEEIDALKEELK 2667
Query: 1055 A-KEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSY 1231
K + ++ L+E I E T L QISQL+N++ K S
Sbjct: 2668 DNKSQEENQQLKSQISELQEQIKQKQNE-------ISETENSLKSQISQLQNELKEKES- 2719
Query: 1232 IDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGK 1411
+ + L E + L+E+ L ++ + +L +E E + K
Sbjct: 2720 --ERGDKSNSLYKEIDSLKEKINNQEIENKADSSQLSDLLKDLKKKLQELTEENETIKSK 2777
Query: 1412 ISENLERI-SKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLE 1588
ISE E+ S++ K+ E +K ++ ++
Sbjct: 2778 ISEEKEKSKSEMAKLEEEKKSLNKELENVNDDEDKEMLE-----------------GEVS 2820
Query: 1589 ELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVN 1768
L + +N+ + ++++ ++S + ++ + L++ E +K ++ + +EKL N
Sbjct: 2821 SLKETLNLKKQINEEQKQKLSQEKEKLTEELSQLNDN----EDLKKEIEQKKEELEKLKN 2876
Query: 1769 DS--LHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFV--KNIQNQVAVSQEQHIEHQCKE 1936
DS L E+ + + ++ E L+ + K +N + ++ +E Q +
Sbjct: 2877 DSSLLQELQDLKKQIEEKSEKQNPELLKQIEDLKKEISEKESENDLITGEKNTVEQQYNK 2936
Query: 1937 ELEGH-IADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAE 2113
+E + + + ++ +E + +++F RI E + + + +E +K +
Sbjct: 2937 LVEQRKYLESTMEAAKKKVSDLRQQCDELSMKNNQF---RIDNEKEFQEIKKSIEEIKGQ 2993
Query: 2114 EAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDL 2293
+ L+ + ++ L ++ + +D Q K A E K E+L
Sbjct: 2994 R--EQLAKKHNEDKRRAREYNTLARQ----KLTDAQQKLDA-----------EKAKNENL 3036
Query: 2294 YTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYE 2473
SE ++K ++ L E+ D + G F Q R+ +
Sbjct: 3037 LKMMSE----------QEKTVSNLEKESEDLEQKNKELEQQMTSTGDFSQDKIEELRKKK 3086
Query: 2474 LELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEE 2653
ELQ+ +E+ ++ + + N L ++ + E + + + E
Sbjct: 3087 EELQKLNDELSQKQKQNIEQSNSLQNEK-----------VTLSNEIESLKSSTEAMEKES 3135
Query: 2654 VQRYKML----CVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHL 2821
+ K L ++ E+ + K D L K+ KE+ S L +++++ +K+ + L
Sbjct: 3136 TEMEKKLEEDKGIISEKSKEKED-LEKKSKEQQEKSDKLKQEVAELQEKAKKITTENTDL 3194
Query: 2822 LKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKM 3001
I DLE I++ E R+K+ + +++ +K+ L ++
Sbjct: 3195 NDKITDLEISISNAE-----------------RRKKDLEEEIEKSSAKSLQEKEKELEEI 3237
Query: 3002 LEDKDKLLCLVGEENKEHKRQIAILEKLKEETENN-PGRVFLQSEEREKIEEQKRVLDQA 3178
E K K V E K+HK+ I LE E + +Q+ ++ +E ++LD+
Sbjct: 3238 AEKKKK---EVREMKKQHKQNIRSLESSISLLEQDIKSLEEIQNSSKKSEQEGLQLLDEK 3294
Query: 3179 LQECEELKNDIQNKHSDIDSLREEQEK-----------LNKQLRCMXXXXXXXXXXXXXX 3325
+ + + K ++++ +D DS ++ EK +N+Q+R +
Sbjct: 3295 VADLKIKKFELEDIIADRDSELKKWEKELLEKNKELSEVNRQIRALK------------- 3341
Query: 3326 XXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNE 3469
+D ++ ++++ +EE+ E +KK +++ + EE E
Sbjct: 3342 -------GDKIDQIKEDIKDIDEEI--ESKKKKLNLNTVEDNDEEEEE 3380
Score = 111 bits (278), Expect = 2e-21
Identities = 240/1237 (19%), Positives = 502/1237 (40%), Gaps = 69/1237 (5%)
Frame = +2
Query: 269 FIEVED--GGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDI 442
F EVED +D K L + + ++ ++ K++ + + + + ++I
Sbjct: 672 FEEVEDLKSKVDDAKILYNDMVDKIDDLKQQRSKVEQKYKDLEKQNKEKSDEIEKVSKEI 731
Query: 443 RNTKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHK 622
K+ LD + + N L+ V A E+ + K EN + +++ LN +
Sbjct: 732 SELKEKLDNLNQ--FKDNTPE---LHQKVDAMNEQ----IVKKSQENEKIQEEMNKLNEE 782
Query: 623 IWSLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHM 802
+ LE ++ + EV+ ETI E+ +K I EK + Q+ L +N+
Sbjct: 783 LQHLENEME-EIEVVNDERETIQEKIDNIKQQIEEKKKSNEEIQDIMNLLIEAENDAQKE 841
Query: 803 VLEKDNIILSLHKQIELQSQNTQSLDCFRR---DEIEDQNIKEEIE-KQIVETIYVTQIQ 970
L+ I+ + ++I + Q Q R+ +E+ +QN K + E K + + T++
Sbjct: 842 -LDDIEIVEAQSEEIRQRIQTLQDNLQDRKKLNNELTEQNNKLQKELKDLQNELDQTELV 900
Query: 971 ELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAE-ISKLSHTLEESIMNSNLESLFT 1147
E +L+ K Q + ++E + ++ K E I K + L+E + +
Sbjct: 901 NDDSESLNKKLDEIKEQINERKSQNENNTEQNEKLIEEIEKFAKELDEIEIIEDKSDKLQ 960
Query: 1148 AEIYE-----NTFRELGDQISQLRNDMYSK----NSYIDSLAS---RIDFLSSECNKLQE 1291
A+I E + ++ +Q + ND+ + +DS++S D+L SE + +
Sbjct: 961 AQISELQKQIDEKQKNNEQTDKSNNDLEHELQITKQKLDSMSSVKNNSDYLKSEIENVNK 1020
Query: 1292 QXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELE------EERGKISENLERIS-KLQK 1450
+ +KLK EL+ EE I++N E + K+
Sbjct: 1021 EIEKIRDTN------------------NKLKQELQDKNKELEEMTDIADNSEELKEKIDS 1062
Query: 1451 MNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNM-----AFGSKLEELTDQINIF 1615
+N E+ +R + +I + ++ + L+E+ QI+
Sbjct: 1063 VNEEITKRVANNTTIDELIRHLHEDLKNAEAKLQSIPHVDDNTDSLQKSLDEVLAQISQK 1122
Query: 1616 NSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKV---LQSFESHIE--KLVNDSLH 1780
D+ E+S + L+N + +K +++ +++ +S IE K N+ +
Sbjct: 1123 QRENDELNDEISRLIQEKEEKTDELNNMETIPDKREEISSEIETVKSQIEEKKKNNEKIA 1182
Query: 1781 EVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQN-QVAVSQEQHIEHQCKEELEG--- 1948
E + + K++ S + L K I+ + +S++Q + K+ELE
Sbjct: 1183 EENKKLAEELENLRQTLSKMETSDQPLENIQKEIETTKQEISEKQKELDELKQELEQIKD 1242
Query: 1949 ---HIADLVLNDFSN---DILSWSRRKEEAVVHDDEFDAERIALLNELKSL--------- 2083
AD + + N I +++ EE +++E +E L EL+ L
Sbjct: 1243 EDQSKADEISEEIENIKTQIDEKNKKNEEIAKNNEEKQSELDEKLKELQDLEEIKDETEE 1302
Query: 2084 -HQDLELLKAE-EAVKSLSNNVGVSTKGIHYFSQLIQEGKDGE------ASDVQG-KSRA 2236
+Q +E + E E K N + + Q +++ ++ E +++ KS
Sbjct: 1303 INQQIEETQKEIETKKQQKENNNKLNEELDKLKQDLEQIENVEDNVEKLTEEIEKVKSDI 1362
Query: 2237 LRRHSTGQAFREPPK--PEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNW 2410
+H +E + E+L + E + +EP + ++ + + N
Sbjct: 1363 DSKHQLNNDIKEANEVVEEELNSLKEELEKIEPVEDKSDEIRKEIVKIQKEIETKKATNC 1422
Query: 2411 PKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXV 2590
+ + LK + E E+ + ++ ++K + N +
Sbjct: 1423 GISESNELLNKELNDLKNQLE-EIAEEKDDSEEIKAEIENLHKSIEEKKEHN-------- 1473
Query: 2591 AEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKL 2770
A E + +E L EE + +++ EE+ S+I+ L +I+EK++ + + E
Sbjct: 1474 ANTQQNNENMKEELSKLQ-EEFDQIEVVEDKAEEIHSEIEKLKSQIEEKNTTNNDIKEA- 1531
Query: 2771 SDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLA 2950
+D L + ++ Q++ + D+E E + S +T L +++ EK+
Sbjct: 1532 NDILNEELNNLQKQYDEI----DVE------EDKSEELSQKVTDL-QKLLEEKKSQNETI 1580
Query: 2951 TKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQS 3130
E + ++ SL+ L++ + +V ++E +++I EKLK+ + + +
Sbjct: 1581 KSGNENILKELQSLQNELDNIE----VVSSSSEEGEKKI---EKLKQMISDKQKQNEETT 1633
Query: 3131 EEREKIEEQKRVLDQALQECEELK---NDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXX 3301
+ E+++ Q + L+ L E +K ND+Q + +I +++K N++ +
Sbjct: 1634 KHNEELDNQIKDLENELNEIIPVKDKSNDLQQQIEEIKDKITDKQKKNEECSQLNTALKE 1693
Query: 3302 XXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAY 3481
I S + +Q ++ +E+K+EI++K + IKE +L E AY
Sbjct: 1694 EYDQLKSEFDNIAVIESKAEEIQQKI----DEIKSEIDQKRKEYQ-DIKEGNDLLEE-AY 1747
Query: 3482 TQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLS 3661
T+K E ++ +VE E Q ++ + Q +R+ R + N E+ KQ L+
Sbjct: 1748 TEKQKELEQIEVVEDKTEDLQNLIDEITEQINSRKSNNLERQVSNETFEKQLGQLKQELN 1807
Query: 3662 ATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKD 3772
+ L+ + ETK K+ ++ DE + D
Sbjct: 1808 DLPQTDDNSESLKEEIEETK--KKLAMMKDEYQRMSD 1842
>ref|XP_653447.1| Viral A-type inclusion protein repeat [Entamoeba histolytica
HM-1:IMSS] gi|56470397|gb|EAL48061.1| Viral A-type
inclusion protein repeat, putative [Entamoeba histolytica
HM-1:IMSS]
Length = 1813
Score = 134 bits (338), Expect = 2e-28
Identities = 237/1181 (20%), Positives = 478/1181 (40%), Gaps = 92/1181 (7%)
Frame = +2
Query: 527 VSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRL 706
++ ++E K+ L + ++N +I +N + + LQ + + E I +
Sbjct: 533 LTEEKESIKQELDSIKADNSTKELEINKINEE----KNQLQNDYDTVQQEKENIQKELNQ 588
Query: 707 LKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCF 886
+K +K+ + +E +Q++ +++ + ++ + L++ I+ +++
Sbjct: 589 IKIEKSQKEEELNKIKEEKQQVEDEKAKLITDIANGNDGLTKLNEVIDKLKDEKENISNE 648
Query: 887 ------RRDEIEDQ--NIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLK 1042
RD I ++ KEEI+++ ETI +L EE +L E + ++E Q ++
Sbjct: 649 LNQIKNERDNISNEFNKTKEEIKQKENETI------QLNEEKSVLLNELNQIKEEKQKIE 702
Query: 1043 DECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTA-EIYENTFRELGDQISQLRNDMYS 1219
DE + K+ EI+KL+ +++++ + L + T + EN + D+ ++ ++
Sbjct: 703 DEKAVIQQEKENEITKLNE--DKTVIENELNQIKTEKQEIENELNQTKDEKQKIEDE--- 757
Query: 1220 KNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLK---ASMEMQCSKLKDE 1390
K+ I L++ D +S KL E+ +K AS + Q ++ ++E
Sbjct: 758 KSKLITELSNGNDGIS----KLNEELTQTKQEKENVLNELNQIKNEFASFKEQNTQKENE 813
Query: 1391 LEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMA 1570
L++E K+ + LE+ NNE+++ + + +I +
Sbjct: 814 LKDENNKVQQELEQ------KNNEVSKLEEEKGNISNELSNTKQELEQKKQEIITITQEK 867
Query: 1571 FGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESH 1750
K EL +Q+ K E+S D IS L L+ K E E+ QK L+ +
Sbjct: 868 -EEKENELKEQVKKIEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEIQKALEEEKEK 926
Query: 1751 IEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQC 1930
+E++ + L E+ A L I + N + L K ++ QE
Sbjct: 927 LERIETE-LKEIKEAKQELEEEKNKTIEEKTNLQQELNENKKIVEELTQTKQE------- 978
Query: 1931 KEELEGHIADLV-----LNDFSNDILSWSRR-KEEAVVHDDEFDAERIALLNELKSLHQD 2092
KEE+ + + + + N I++ ++ KEE + +E E +L ++ L
Sbjct: 979 KEEINNELNSIKEEKKRIEEEKNQIINENKEIKEENIKSIEEKTQEINSLTTSIEELKGR 1038
Query: 2093 LELLKAE--------EAVKSLSNNVGVSTKGI-------HYFSQLIQEGKDGEASDVQGK 2227
LE K E + V S N++ + +G+ H +Q+ +G +++
Sbjct: 1039 LEESKGERIEIEKERDRVISELNDIKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEM--- 1095
Query: 2228 SRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSP--- 2398
+L T +E E + ++ + E KK L + ++
Sbjct: 1096 INSLNNQITQLNEKEKQMNEQVMALQTQLSQSNINLEEVKKDLIESQNKYTQINEEKDCV 1155
Query: 2399 --LRNWPKEQL------LGHFKQSFAGLKREYE---LELQRKTEEIYDLKRLLLNEKNGL 2545
RN E+ L K+ L+ +Y+ LEL + +E+ L L EK L
Sbjct: 1156 EQERNKINEEYKTVNEELEKNKKELNDLQTKYDNEILELNKNKDELNSLINNLKEEKTNL 1215
Query: 2546 HAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKM---LCVLKEE---LQSKI 2707
+ E++ + V + N+ L + ++ ++ L +KEE ++ +
Sbjct: 1216 EEQVKKMEEEKSKLITELSNGSDGVSKLNEELTQTKQEKEEINNELNSIKEEKKRIEEEK 1275
Query: 2708 DSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCS 2887
+ ++ E KE + + E+ + LK+ + + L I ++ + + E
Sbjct: 1276 NQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQ--- 1332
Query: 2888 DVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKL----------LCLVG 3037
E++ + ++ +EQE + Q L ++ E+K KL L +
Sbjct: 1333 --------EIICDNNKEIAKFKEEQENL---QKELNQIKEEKSKLITDLSNGNDGLSKLN 1381
Query: 3038 EE----NKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVL-----------D 3172
EE NKE + LE LKEE + +++E K++E+K L +
Sbjct: 1382 EEIETINKEKEGIRKELESLKEENNKIQDELEQKNQELSKVKEEKEKLIHDLTNGNDGIN 1441
Query: 3173 QALQECEELKNDIQNK-------HSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXX 3331
Q ++ ++KND + ++I+ L+ E E+L+ L
Sbjct: 1442 QLNEDLNQIKNDKEELTEKNVQLQNEINKLKSENEELSNNLSFEKEGLKQVNEEVNAIKE 1501
Query: 3332 XXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEA 3511
+ + ++ E R EEL + + I + EKE+LN+ ++Q
Sbjct: 1502 ERDELVKQIKKIEEEKRKVEEELNFNGSEVNEQIAQINNEKEQLNQEC----NELKQNLK 1557
Query: 3512 VLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKER 3691
L K+ E EQ+ ES++ +E+ ++ ++ + + +LK++ +ELQ KE
Sbjct: 1558 ELQSKIEEIEQE---KESNEIKKKEELQELQEEITEKDNDIKNLKEEIERIEKELQEKEE 1614
Query: 3692 DLEVAMTETKFLKE---KLL----VSDENLKEKDLQLRAFE 3793
D+E T+ L+E KL + +E KEK+ FE
Sbjct: 1615 DMEQMSNNTEELEELKNKLTETQRLLEEEKKEKESISNEFE 1655
Score = 125 bits (313), Expect = 2e-25
Identities = 228/1242 (18%), Positives = 523/1242 (42%), Gaps = 73/1242 (5%)
Frame = +2
Query: 302 RKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESG 481
++ E ++ E +++ME + L N G D G+ L E++ TK + + +
Sbjct: 326 KEEKENELKEQVKKMEEEKSKLITELSN-----GSD--GISKLNEELTQTKQEKEEINNE 378
Query: 482 LYVSNVVSDAV---LNGVVSAQEE--EFKEALAAKDSENFLLNKKIEDLNHKIWSLEETL 646
L + N +++ +E E KE + + E +K ++ N+++ + T+
Sbjct: 379 LNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTI 438
Query: 647 QYK-EEVILSSHETISERDRLLKDFIHEKDLMQQ---RAQETEQKLASRDNEMMHMVLEK 814
Q + +E+ + E I + ++ + F E++ +Q+ + +E +QK + NE++ + +K
Sbjct: 439 QTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELVDVKTQK 498
Query: 815 DNIILSLHKQIELQSQNTQSLDCFRRDEIEDQN-IKEEIE--KQIVETIYVT------QI 967
+N + L ++ E +++ +E++N + EE E KQ +++I +I
Sbjct: 499 ENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIKADNSTKELEI 558
Query: 968 QELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFT 1147
++ EE + L+ + Q E ++++ E + ++ K + +L+ EE + ++
Sbjct: 559 NKINEEKNQLQNDYDTVQQEKENIQKELNQIKIEKSQKEEELNKIKEEKQQVEDEKAKLI 618
Query: 1148 AEIYENT--FRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXX 1321
+I +L + I +L+++ + ++ ++ + + D +S+E NK +E+
Sbjct: 619 TDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNISNEFNKTKEEIKQKENETI 678
Query: 1322 XXXXXXXTLKASMEMQCSKLKDELEEERGKISENLER-ISKLQK----MNNELAERSKSQ 1486
L + Q + K ++E+E+ I + E I+KL + + NEL + +
Sbjct: 679 QLNEEKSVLLNELN-QIKEEKQKIEDEKAVIQQEKENEITKLNEDKTVIENELNQIKTEK 737
Query: 1487 NSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDT 1666
I ++ ++L D I+ N + + + E L+
Sbjct: 738 QEIENELNQTKDEKQKIEDEKSKLI-----TELSNGNDGISKLNEELTQTKQEKENVLNE 792
Query: 1667 ISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDN 1846
++ ++ ++ K + + + L+ + +++ + +EV L ++ +++ N
Sbjct: 793 LNQIKNEFASFKEQNTQKENELKDENNKVQQELEQKNNEVSK----LEEEKGNISNELSN 848
Query: 1847 SGETLRAFVKNIQNQVAVSQE-QHIEHQCKEELEG--HIADLVLNDFSNDILSWSRRKEE 2017
+ + L + Q + ++QE + E++ KE+++ ++ + SN S+ EE
Sbjct: 849 TKQELE---QKKQEIITITQEKEEKENELKEQVKKIEEEKSKLITELSNGSDGISKLNEE 905
Query: 2018 AVVHDDEFDAERIALLNELKSLHQ-DLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEG 2194
E + + AL E + L + + EL + +EA + L + + Q + E
Sbjct: 906 LTQTKQEKEEIQKALEEEKEKLERIETELKEIKEAKQELEEEKNKTIEEKTNLQQELNEN 965
Query: 2195 KDGEASDVQGKSRALRRHSTGQAFREPPK--PEDLYTTYSEGKIVEPHPTE--EKKLLAI 2362
K Q K ++ + +E K E+ +E K ++ + E+K I
Sbjct: 966 KKIVEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEENIKSIEEKTQEI 1025
Query: 2363 LAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNG 2542
+ T+ E+L G ++S G + E E E R E+ D+K L NE G
Sbjct: 1026 NSLTTSI-----------EELKGRLEES-KGERIEIEKERDRVISELNDIK--LQNE--G 1069
Query: 2543 LHAXXXXXXXXXXXXVAEITGKFEKVLQE--NKL--LPVEEVQRYKMLCVLKEEL-QSKI 2707
+ G +++ N++ L +E Q + + L+ +L QS I
Sbjct: 1070 MKKQVEEAHNRMTEMQKSFEGSENEMINSLNNQITQLNEKEKQMNEQVMALQTQLSQSNI 1129
Query: 2708 DSLLKEIKE---KDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITD-REIMT 2875
+ L+E+K+ + N + D +++ + E + +LE + ++ T
Sbjct: 1130 N--LEEVKKDLIESQNKYTQINEEKDCVEQERNKINEEYKTVNE--ELEKNKKELNDLQT 1185
Query: 2876 SVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVG------ 3037
+++L E+ + K+ SL +E + ++KM E+K KL+ +
Sbjct: 1186 KYDNEIL-----ELNKNKDELNSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNGSDGV 1240
Query: 3038 -----------EENKEHKRQIAILEKLKEETENNPGRVFLQS----EEREKIEEQKRVLD 3172
+E +E ++ +++ K+ E ++ ++ EE+EKIEE+K+ L
Sbjct: 1241 SKLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELL 1300
Query: 3173 QALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISS 3352
+ +++ +E N +QN+ + I + +E E+ N+++ C
Sbjct: 1301 KEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIIC-------------DNNKEIAKFKE 1347
Query: 3353 NLDSMQLELRNYNEEL----------KNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQ 3502
+++Q EL EE + + K + +I+ + KEKE + + L +++++
Sbjct: 1348 EQENLQKELNQIKEEKSKLITDLSNGNDGLSKLNEEIETINKEKEGIRKEL----ESLKE 1403
Query: 3503 KEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQS 3682
+ + ++L + Q++ ++ + D +N L E+ +K TE+
Sbjct: 1404 ENNKIQDELEQKNQELSKVKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDKEELTEKNVQ 1463
Query: 3683 KERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSE 3808
+ ++ +E + L L E LK+ + ++ A + E
Sbjct: 1464 LQNEINKLKSENEELSNNLSFEKEGLKQVNEEVNAIKEERDE 1505
Score = 122 bits (306), Expect = 1e-24
Identities = 241/1226 (19%), Positives = 509/1226 (41%), Gaps = 56/1226 (4%)
Frame = +2
Query: 275 EVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTK 454
+ +D L T+ E + + +E +E + D + + N +N G+ L E++ K
Sbjct: 201 DAQDSLLKTKMKSEMEAKKKVEILENEKKDLIDKMAN-------ENDGMSKLNEELTQIK 253
Query: 455 DLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSL 634
+ +++ N ++ ++E K+S N L + D + K L
Sbjct: 254 NEKESIN--------------NELIQTKQE--------KESINNELTQLKTDNDQKENEL 291
Query: 635 EETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEK 814
+ K+EVI + + E ++++ + K +++ E ++++ + E ++ E
Sbjct: 292 NQVRHEKDEVIEKFNTSKEENEKIMNELSQLKQEKEEKENELKEQVKKMEEEKSKLITEL 351
Query: 815 DNIILSLHKQIELQSQNTQSLDCFRRDEIEDQ--NIKEEIEKQIVE--TIYVTQIQELGE 982
N + K E +Q Q ++EI ++ +IKEE +K+I E + + +E+ E
Sbjct: 352 SNGSDGISKLNEELTQTKQE-----KEEINNELNSIKEE-KKRIEEEKNQIINENKEIKE 405
Query: 983 EHDLLRLESAKYQDEIQSLKD---ECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAE 1153
E + + E + EI+ K+ + + + Q + ++ +E I ++N E E
Sbjct: 406 EKEKIEEEKKELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKE 465
Query: 1154 IYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXX 1333
EN +EL + + KN +D + +E NKL+E+
Sbjct: 466 EQENLQKELNQIKEEKQKTENEKNELVDVKTQK----ENELNKLKEEKEQIFNEKT---- 517
Query: 1334 XXXTLKASMEMQCSKLKDELEEERGKISENLERI-----SKLQKMNNELAERSKSQNSIX 1498
T++ S+ Q + K++L EE+ I + L+ I +K ++N E+++ QN
Sbjct: 518 ---TIENSLN-QIVEEKNKLTEEKESIKQELDSIKADNSTKELEINKINEEKNQLQNDYD 573
Query: 1499 XXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSL 1678
+ + K EEL N + ++K+ D + L
Sbjct: 574 TVQQEKENIQKELNQ-----IKIEKSQKEEEL-------NKIKEEKQQVE----DEKAKL 617
Query: 1679 QTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKV-DNSGE 1855
T ++N + K +V+ + E + N+ L+++ + ++++ F ++ E
Sbjct: 618 ITDIANGNDGLTKLNEVIDKLKDEKENISNE-LNQIKNERDNISNEFNKTKEEIKQKENE 676
Query: 1856 TLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDD 2035
T++ N + V +++ I+ + K+++E A ++ + N+I + K +
Sbjct: 677 TIQL---NEEKSVLLNELNQIKEE-KQKIEDEKA-VIQQEKENEITKLNEDKTVIENELN 731
Query: 2036 EFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASD 2215
+ E+ + NEL + + K E+ L + GI ++ + + K E +
Sbjct: 732 QIKTEKQEIENELNQTKDEKQ--KIEDEKSKLITELSNGNDGISKLNEELTQTKQ-EKEN 788
Query: 2216 VQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDS 2395
V + ++ + K +L E V+ ++ ++ L E + S+
Sbjct: 789 VLNELNQIKNEFASFKEQNTQKENELK---DENNKVQQELEQKNNEVSKLEEEKGNISNE 845
Query: 2396 PLRNWPKEQLLGHFKQSFAGL---KREYELELQRKTEEIYDLKRLLLNE-KNGLHAXXXX 2563
L N +E L KQ + K E E EL+ + ++I + K L+ E NG +
Sbjct: 846 -LSNTKQE--LEQKKQEIITITQEKEEKENELKEQVKKIEEEKSKLITELSNG--SDGIS 900
Query: 2564 XXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKM-LCVLKEELQSKIDSLLKEIKEKD 2740
+ + +K L+E K E+++R + L +KE Q + K I+EK
Sbjct: 901 KLNEELTQTKQEKEEIQKALEEEK----EKLERIETELKEIKEAKQELEEEKNKTIEEKT 956
Query: 2741 SNSKVLAE--KLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVE 2914
+ + L E K+ + L ++ + ++ L I + + I + + + + ++
Sbjct: 957 NLQQELNENKKIVEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEENIK 1016
Query: 2915 MVREKEFSL-SLATKEQETVNQKQMSLRKMLE---DKDKLLCLVGE---ENKEHKRQIA- 3070
+ EK + SL T +E + + S + +E ++D+++ + + +N+ K+Q+
Sbjct: 1017 SIEEKTQEINSLTTSIEELKGRLEESKGERIEIEKERDRVISELNDIKLQNEGMKKQVEE 1076
Query: 3071 ----------ILEKLKEETENNPGRVFLQSEEREK-IEEQKRVLDQALQEC----EELKN 3205
E + E N+ Q E+EK + EQ L L + EE+K
Sbjct: 1077 AHNRMTEMQKSFEGSENEMINSLNNQITQLNEKEKQMNEQVMALQTQLSQSNINLEEVKK 1136
Query: 3206 DI---QNKHSDI----DSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDS 3364
D+ QNK++ I D + +E+ K+N++ + ++ L+
Sbjct: 1137 DLIESQNKYTQINEEKDCVEQERNKINEEYKT---------------------VNEELEK 1175
Query: 3365 MQLELRNYNEELKNEI---EKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFE 3535
+ EL + + NEI K +++ LI +E L K ME++++ L+ +L
Sbjct: 1176 NKKELNDLQTKYDNEILELNKNKDELNSLINNLKEEKTNLEEQVKKMEEEKSKLITELSN 1235
Query: 3536 GEQKILLLESSQSATREQTEKYRDLLNSLTEEHADL---KKQFLSATEELQSKERDLEVA 3706
G + L + T+++ E+ + LNS+ EE + K Q ++ +E++ ++ +E
Sbjct: 1236 GSDGVSKLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEE 1295
Query: 3707 MTETKFLKEKLLVSDENLKEKDLQLR 3784
K++LL E KE + QL+
Sbjct: 1296 -------KKELLKEIEKEKEGNNQLQ 1314
Score = 116 bits (291), Expect = 7e-23
Identities = 233/1200 (19%), Positives = 485/1200 (40%), Gaps = 52/1200 (4%)
Frame = +2
Query: 329 ETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGLYVSNVVSD 508
E L +++ + + + D+ N G+ L E I KD + + + L N + +
Sbjct: 598 EELNKIKEEKQQVEDEKAKLITDIANGNDGLTKLNEVIDKLKDEKENISNEL---NQIKN 654
Query: 509 AVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQ-YKEEVILSSHET 685
N +S + + KE + K++E LN++ L +++ ++E Q ++E + E
Sbjct: 655 ERDN--ISNEFNKTKEEIKQKENETIQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQEK 712
Query: 686 ISERDRLLKD---FIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQ 856
+E +L +D +E + ++ QE E +L +E + EK +I L +
Sbjct: 713 ENEITKLNEDKTVIENELNQIKTEKQEIENELNQTKDEKQKIEDEKSKLITELSNGNDGI 772
Query: 857 SQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQS 1036
S+ + L ++ E +N+ E+ + ++ + + ++ ++ + L+ E+ K Q E++
Sbjct: 773 SKLNEELTQTKQ---EKENVLNELNQ--IKNEFASFKEQNTQKENELKDENNKVQQELEQ 827
Query: 1037 LKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMY 1216
+E E K ++LS+T +E + E + + E EL +Q+ ++ +
Sbjct: 828 KNNEVSKLEEEKGNISNELSNTKQE-LEQKKQEIITITQEKEEKENELKEQVKKIEEEKS 886
Query: 1217 SKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELE 1396
+ + + + I L+ E + +++ ++ ++ + + K ELE
Sbjct: 887 KLITELSNGSDGISKLNEELTQTKQEKEEIQKALEEEKEKLERIETELK-EIKEAKQELE 945
Query: 1397 EERGKISE---NLER-ISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVN 1564
EE+ K E NL++ +++ +K+ EL + + + I ++N
Sbjct: 946 EEKNKTIEEKTNLQQELNENKKIVEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIIN 1005
Query: 1565 MAFGSK------LEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQK 1726
K +EE T +IN + I+ E+ G L+ + + ++ +
Sbjct: 1006 ENKEIKEENIKSIEEKTQEINSLTTSIE----ELKGRLEESKGERIEIEKERDRVISELN 1061
Query: 1727 VLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQ 1906
++ ++K V ++ + + S +I+ ++N L K + QV Q
Sbjct: 1062 DIKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMINSLNNQITQLNEKEKQMNEQVMALQ 1121
Query: 1907 EQ------HIEHQCKEELEGHIADLVLNDFSNDILSWSRRK--EEAVVHDDEFDAERIAL 2062
Q ++E K+ +E +N+ D + R K EE ++E + + L
Sbjct: 1122 TQLSQSNINLEEVKKDLIESQNKYTQINE-EKDCVEQERNKINEEYKTVNEELEKNKKEL 1180
Query: 2063 LNELKSLHQD--LELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRA 2236
N+L++ + + LEL K ++ + SL NN+ + + ++E K +++ S
Sbjct: 1181 -NDLQTKYDNEILELNKNKDELNSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNGSDG 1239
Query: 2237 LRRHSTGQAFREPPKPE---DLYTTYSEGKIVEPHPTE---EKKLLAILAFETADASDSP 2398
+ + + + K E +L + E K +E + E K + + +
Sbjct: 1240 VSKLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKEL 1299
Query: 2399 LRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIY--DLKRL--LLNEKNGLHAXXXXX 2566
L+ KE+ + Q+ + E++ K +EI + K + E+ L
Sbjct: 1300 LKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQI 1359
Query: 2567 XXXXXXXVAEITGK---FEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEK 2737
+ +++ K+ +E + + E+ K L LKEE +KI L++ ++
Sbjct: 1360 KEEKSKLITDLSNGNDGLSKLNEEIETINKEKEGIRKELESLKEE-NNKIQDELEQKNQE 1418
Query: 2738 DSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEM 2917
S K EKL L D + + L I + + +T++ + + L + E+
Sbjct: 1419 LSKVKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDKEELTEKNVQLQNEINKLKSENEEL 1478
Query: 2918 VREKEFSLSLATKEQETVN-------QKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAIL 3076
F + E VN + ++K+ E+K K+ + E QIA +
Sbjct: 1479 SNNLSFEKEGLKQVNEEVNAIKEERDELVKQIKKIEEEKRKVEEELNFNGSEVNEQIAQI 1538
Query: 3077 EKLKEETENNPGRVFLQSEER----EKIEEQKRVLD-QALQECEELKNDIQNKHSDIDSL 3241
KE+ + +E E+IE++K + + +E +EL+ +I K +DI +L
Sbjct: 1539 NNEKEQLNQECNELKQNLKELQSKIEEIEQEKESNEIKKKEELQELQEEITEKDNDIKNL 1598
Query: 3242 REEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKK 3421
+EE E++ K+L+ +S+N + + EELKN++ +
Sbjct: 1599 KEEIERIEKELQ--------------EKEEDMEQMSNNTEEL--------EELKNKLTET 1636
Query: 3422 STDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKY 3601
++ KEKE ++ E KE VLVE + + E Q E+ E
Sbjct: 1637 QRLLEEEKKEKESISNEFE------ETKEQVLVELQRVNNEMNKMNEIKQEDENEKEE-- 1688
Query: 3602 RDLLNSLTEEHADLKKQFLSATEELQSKER---DLEVAMTETKFLKEKLLVSDENLKEKD 3772
L E LK Q E+L+ + +L TE + +K+ ++ L D
Sbjct: 1689 ------LQEHINKLKSQIERENEQLKEVSKLKWELSELKTENESMKQMIMNKKSLLDNTD 1742
Score = 96.3 bits (238), Expect = 9e-17
Identities = 201/1016 (19%), Positives = 403/1016 (39%), Gaps = 15/1016 (1%)
Frame = +2
Query: 275 EVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTK 454
E++D ++ LE K E + ++E +G+ +N L N +L Q + + ++ +
Sbjct: 813 ELKDENNKVQQELEQKNNE-VSKLEEEKGNISNELSNTKQELEQKKQEIITITQEKEEKE 871
Query: 455 -DLLDTVESGLYVSNVVSDAVLNGV--VSAQEEEFKEALAAKDSENFLLNKKIEDLNHKI 625
+L + V+ + + + NG +S EE + K+ L ++ E L
Sbjct: 872 NELKEQVKKIEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEIQKALEEEKEKLERIE 931
Query: 626 WSLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMV 805
L+E + K+E+ ++TI E+ L ++ K ++++ Q T+Q+ +NE+ +
Sbjct: 932 TELKEIKEAKQELEEEKNKTIEEKTNLQQELNENKKIVEELTQ-TKQEKEEINNELNSIK 990
Query: 806 LEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELG-- 979
EK I + + Q ++ EI+++NIK EK T I+EL
Sbjct: 991 EEKKRI----------EEEKNQIIN--ENKEIKEENIKSIEEKTQEINSLTTSIEELKGR 1038
Query: 980 -EEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEI 1156
EE R+E K +D + S ++ + + ++ + + + E M + E I
Sbjct: 1039 LEESKGERIEIEKERDRVISELNDIKLQNEGMKKQVEEAHNRMTE--MQKSFEGSENEMI 1096
Query: 1157 YENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXX 1336
L +QI+QL N + +L +++ S+ N E+
Sbjct: 1097 -----NSLNNQITQLNEKEKQMNEQVMALQTQL----SQSNINLEEVKKDLIESQNKYTQ 1147
Query: 1337 XXTLKASMEMQCSKLKDELEEERGKISENLERISKLQ-KMNNELAERSKSQNSIXXXXXX 1513
K +E + +K+ +E + ++ +N + ++ LQ K +NE+ E +K+++ +
Sbjct: 1148 INEEKDCVEQERNKINEEYKTVNEELEKNKKELNDLQTKYDNEILELNKNKDEL------ 1201
Query: 1514 XXXXXXXXXXXXXXVVNMAFGSKLEELT---DQINIFNSVIDKKEAEVSGHLDTISSLQT 1684
N + EE T +Q+ K E+S D +S L
Sbjct: 1202 ----------------NSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNGSDGVSKLNE 1245
Query: 1685 VLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSG-ETL 1861
L+ K E E+ L S + +++ E + + N K++ E L
Sbjct: 1246 ELTQTKQEKEEINNELNSIKEEKKRI-----EEEKNQIINENKEIKEEKEKIEEEKKELL 1300
Query: 1862 RAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEF 2041
+ K + + E + +E+E +++ D + +I + +E ++
Sbjct: 1301 KEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIIC-DNNKEIAKFKEEQENLQKELNQI 1359
Query: 2042 DAERIALLNELKSLHQDLELLKAE-EAVKSLSNNVGVSTKGIHYFSQLIQ---EGKDGEA 2209
E+ L+ +L + + L L E E + + + + + IQ E K+ E
Sbjct: 1360 KEEKSKLITDLSNGNDGLSKLNEEIETINKEKEGIRKELESLKEENNKIQDELEQKNQEL 1419
Query: 2210 SDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADAS 2389
S V+ + L T EDL ++ + + + + + L E + S
Sbjct: 1420 SKVKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDKEELTEKNVQLQNEINKLKSENEELS 1479
Query: 2390 DSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXX 2569
++ ++ KE L + +K E + EL ++ ++I + KR + E N
Sbjct: 1480 NN--LSFEKEGLK-QVNEEVNAIKEERD-ELVKQIKKIEEEKRKVEEELN-------FNG 1528
Query: 2570 XXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNS 2749
+A+I + E++ QE L Q K ELQSKI+ + +E K+SN
Sbjct: 1529 SEVNEQIAQINNEKEQLNQECNELK----QNLK-------ELQSKIEEIEQE---KESNE 1574
Query: 2750 KVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREK 2929
E+L + ++ + +L + I +E + ++E E
Sbjct: 1575 IKKKEELQELQEEITEKDNDIKNLKEEIERIEKELQEKE-------------------ED 1615
Query: 2930 EFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNP 3109
+S T+E E + K +++LE EE KE E + E E
Sbjct: 1616 MEQMSNNTEELEELKNKLTETQRLLE----------EEKKEK-------ESISNEFEETK 1658
Query: 3110 GRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLR 3277
+V + E +++ + +++ QE E K ++Q I+ L+ + E+ N+QL+
Sbjct: 1659 EQVLV---ELQRVNNEMNKMNEIKQEDENEKEELQ---EHINKLKSQIERENEQLK 1708
Score = 77.0 bits (188), Expect = 6e-11
Identities = 82/389 (21%), Positives = 175/389 (44%), Gaps = 8/389 (2%)
Frame = +2
Query: 2642 PVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHL 2821
PVE+VQ+ K + E QS+ + L+ + S + E+ + ++++ ++E+H
Sbjct: 74 PVEKVQQRKGFLSRRSETQSQTNELVSTPPHEKSGDEAKNEQKQSS-SQTSESTEKETHK 132
Query: 2822 LKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKM 3001
K ++ L + T E S + + + T + S+
Sbjct: 133 -KRLSFLGRKSFSKRNSTENTGH----------SSSEHSATSSLASETTAEEVNRSVNAQ 181
Query: 3002 LEDKDKLLCLVGEE-NKEHKRQIAILE-KLKEETENNPGRVFLQSEEREKIEEQKRVLD- 3172
+E+++K L EE K+ Q ++L+ K+K E E L++E+++ I++ D
Sbjct: 182 IEEENKRLQNENEELKKKCDAQDSLLKTKMKSEMEAKKKVEILENEKKDLIDKMANENDG 241
Query: 3173 --QALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXI 3346
+ +E ++KN+ ++ ++++ ++E+E +N +L + +
Sbjct: 242 MSKLNEELTQIKNEKESINNELIQTKQEKESINNELTQLKTDNDQKENELNQVRHEKDEV 301
Query: 3347 SSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEK 3526
++ + E NE++ NE+ + L +EKEE L K ME++++ L+ +
Sbjct: 302 IEKFNTSKEE----NEKIMNELSQ-------LKQEKEEKENELKEQVKKMEEEKSKLITE 350
Query: 3527 LFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADL---KKQFLSATEELQSKERDL 3697
L G I L + T+++ E+ + LNS+ EE + K Q ++ +E++ ++ +
Sbjct: 351 LSNGSDGISKLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKI 410
Query: 3698 EVAMTETKFLKEKLLVSDENLKEKDLQLR 3784
E K++LL E KE + QL+
Sbjct: 411 EEE-------KKELLKEIEKEKEGNNQLQ 432
>ref|XP_001581403.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121915630|gb|EAY20417.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 4263
Score = 134 bits (338), Expect = 2e-28
Identities = 265/1251 (21%), Positives = 506/1251 (40%), Gaps = 75/1251 (5%)
Frame = +2
Query: 275 EVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTK 454
E+++ T + L ++ E E + + EG+ + ++ + + + + DI++ +
Sbjct: 1368 EIQEENRQTLEQLAKQLQEAEEDINVLEGNC----QVYEQEIAEKDKQIEQMTNDIKSLE 1423
Query: 455 DLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSL 634
++++ SN + L V+ +EEE K+ L SEN + I+ L I
Sbjct: 1424 EVINEQ------SNTIDS--LKQDVATKEEEIKQ-LKQTVSEN---EEVIKQLQTDIEQK 1471
Query: 635 EETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHM---V 805
+ +Q +E I +TIS+RD +K +Q ++ +Q +A ++NE+ + +
Sbjct: 1472 DAEIQKNKEEIEQHKQTISQRDETIKQ-------LQSEIEQHKQTIADKNNEIEQLKNTI 1524
Query: 806 LEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQI---------VETIYV 958
E++ I L +IE Q D E Q KEEIE+Q +E +
Sbjct: 1525 SEREETIKQLQNEIEQHKQTMAERDA------EIQKNKEEIEQQKQTISNNNNEIEQLKK 1578
Query: 959 TQIQELGEEHDLLRLESAKYQDEIQSLKDEC--HAKEMSKQ-AEISKLSHTLEESIMNSN 1129
T I E E + L+ A+ + I+ L++E H + +S++ AEI +L T+++
Sbjct: 1579 T-ISERDAEIEQLKKTIAERDESIKQLQNEIEQHKQTISQRDAEIEQLKQTVQQRDQ--- 1634
Query: 1130 LESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXX 1309
T E+ ++L +I Q + + KN+ I+ L ++ +LQ +
Sbjct: 1635 -----TIAEKEDLIKQLQSEIEQHKQTISDKNNEIEQLKQTVNARDEAIKQLQSEIEQHK 1689
Query: 1310 XXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSK--S 1483
A + + K K+E+E+++ IS+ E I +LQ NE+ + + S
Sbjct: 1690 QTI-----------AERDAEIQKNKEEIEQQKQTISQRDETIKQLQ---NEIEQHKQTIS 1735
Query: 1484 QNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLD 1663
Q + S++E+ I ++ I K + E+
Sbjct: 1736 QRDAEIEQLKQTVQQSDQTIAEKEDLIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQ 1795
Query: 1664 TISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVD 1843
TIS + + EIE++++ + E IE+ ++ E D++ L +
Sbjct: 1796 TISQRDESIKQMQSEIEQNKQTIADREKEIEQH-KQTIAERDNSIKQLQEEIEQHKQTIA 1854
Query: 1844 NSGETLRAFVKNIQNQV----AVSQEQHIEHQCKEELEGHIADLV-----LNDFSNDILS 1996
++ + IQ + A++ E + ELE + +L+ LND +D L+
Sbjct: 1855 ERDAEIQKNKEEIQQKNEAINALTNEGEEKRLKILELEANNENLINKVKELNDSVSD-LN 1913
Query: 1997 WSRRKEEAVVH---DDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIH 2167
S + +VV D+ D + E+KS +Q ++ + ++ ++SL+N + + I
Sbjct: 1914 LSTENQNSVVKQMTDEIKDLNKQIHELEVKSENQQKQIEEKDKEIQSLTNTKAQNEELI- 1972
Query: 2168 YFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKP-EDLYTTYSEG-KIVEPHPTE 2341
+L +E ++ + Q + Q+ E EDL E + + E
Sbjct: 1973 --KKLQEEVENLTNTKNQNEETIKNLQEQVQSLTETKNQNEDLIKKQQEQIQSLTNTKNE 2030
Query: 2342 EKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRL 2521
++ + L + +++ N + L QS K E +++++ EEI L
Sbjct: 2031 NEETIKNLQEQVQSLTETKATNEETIKKLQGEVQSLTETKATNEEQIKKQQEEIQSLS-- 2088
Query: 2522 LLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQS 2701
N KN E +K+ +E + L + Q + + L+EE+Q+
Sbjct: 2089 --NTKN------------------ENEELIKKLQEEIQNLTNTKTQNEEQIKKLQEEIQN 2128
Query: 2702 KIDSLLKEIKEKDSNSKVLAEKLSDALKKSAD-------HAQRESHLLKH--------IA 2836
L K+ EKD KLS L S+D +AQ E + L I+
Sbjct: 2129 ----LQKQNAEKDDKINEFNAKLS-TLSSSSDELTTKFINAQNEINQLTKQNNEKDNLIS 2183
Query: 2837 DLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQ-MSLRKMLEDK 3013
L I+D E S + + L E ++ L +++ +KQ + K ++
Sbjct: 2184 QLNQKISDLENAKSQLENEKSQLIQEKTNLEQEKAQLLEQKKNLEEEKQKLETEKTNLEQ 2243
Query: 3014 DKLLCLVGEENKEHKRQIAILEKLKEETENNP---GRVFLQSEEREKIEEQKRVLDQALQ 3184
+K + + N E ++ I EK E E + L+ E+ + IEE+ + + +
Sbjct: 2244 EKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAK 2303
Query: 3185 ECEELKNDIQNKHSDID---SLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSN 3355
EE N Q K I+ +L +E+ KL ++ + +
Sbjct: 2304 LIEEKTNLEQEKAKPIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEE 2363
Query: 3356 LDSMQLELRNYNEELKNEIEKKSTDID----------LLIKEKEELNE---RLAYTQKAM 3496
+++ E EE N ++K+ I+ LI+EK L + +L + +
Sbjct: 2364 KTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNL 2423
Query: 3497 EQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADL---KKQFLSAT 3667
EQ++A L+E+ EQ+ L + E+ ++ L E+ +L K Q L
Sbjct: 2424 EQEKAKLIEEKTNLEQEKSQLLDQKKNLEEEKQRLETEKAKLIEDKTNLEQEKAQLLEQK 2483
Query: 3668 EELQSKERDLEVAMTET-KFLKEK-----LLVSDENLKEKDLQLRAFEIAN 3802
+ L+ ++ LE + K ++EK L S N+K KDL L + N
Sbjct: 2484 KNLEEEKAKLEEEKAQAQKTIEEKDQEIEDLTSQINVKTKDLSLLESDFNN 2534
Score = 127 bits (320), Expect = 3e-26
Identities = 225/1139 (19%), Positives = 461/1139 (40%), Gaps = 55/1139 (4%)
Frame = +2
Query: 527 VSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERD-- 700
+ ++ E+ K+ +A +D+E ++IE I +ET++ + I +TIS+RD
Sbjct: 1681 LQSEIEQHKQTIAERDAEIQKNKEEIEQQKQTISQRDETIKQLQNEIEQHKQTISQRDAE 1740
Query: 701 -RLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQN-TQS 874
LK + + D ++ ++L S + + E+D I ++IE Q Q +Q
Sbjct: 1741 IEQLKQTVQQSDQTIAEKEDLIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQTISQR 1800
Query: 875 LDCFRRDEIEDQNIKEEI---EKQIVETIYV-----TQIQELGEEHDLLRLESAKYQDEI 1030
+ ++ + E + K+ I EK+I + I++L EE + + A+ EI
Sbjct: 1801 DESIKQMQSEIEQNKQTIADREKEIEQHKQTIAERDNSIKQLQEEIEQHKQTIAERDAEI 1860
Query: 1031 QSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRND 1210
Q K+E K I+ L++ EE + LE E N +EL D +S L
Sbjct: 1861 QKNKEEI----QQKNEAINALTNEGEEKRLKI-LELEANNENLINKVKELNDSVSDLNLS 1915
Query: 1211 MYSKNSYIDSLASRIDFLSSECNKLQ---EQXXXXXXXXXXXXXXXXTLKASMEMQCSKL 1381
++NS + + I L+ + ++L+ E KA E KL
Sbjct: 1916 TENQNSVVKQMTDEIKDLNKQIHELEVKSENQQKQIEEKDKEIQSLTNTKAQNEELIKKL 1975
Query: 1382 KDELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVV 1561
++E+E ++N E I LQ+ L E +K+QN
Sbjct: 1976 QEEVENLTNTKNQNEETIKNLQEQVQSLTE-TKNQNEDLIKKQQEQIQSLTNTKNENEET 2034
Query: 1562 NMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIE-------KS 1720
+++ LT+ I K + EV +T ++ + + Q+ EI+ ++
Sbjct: 2035 IKNLQEQVQSLTETKATNEETIKKLQGEVQSLTETKATNEEQIKKQQEEIQSLSNTKNEN 2094
Query: 1721 QKVLQSFESHIEKLVN------DSLHEVDSAFCSLN----------SRFYSLIHKVDNSG 1852
+++++ + I+ L N + + ++ +L + F + + + +S
Sbjct: 2095 EELIKKLQEEIQNLTNTKTQNEEQIKKLQEEIQNLQKQNAEKDDKINEFNAKLSTLSSSS 2154
Query: 1853 ETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHD 2032
+ L N QN++ +Q+ E K+ L + + ++D N K + +
Sbjct: 2155 DELTTKFINAQNEINQLTKQNNE---KDNLISQL-NQKISDLENAKSQLENEKSQLIQEK 2210
Query: 2033 DEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEAS 2212
+ E+ LL + K+L ++ + L+ E+ T ++LI+E + E
Sbjct: 2211 TNLEQEKAQLLEQKKNLEEEKQKLETEK------------TNLEQEKAKLIEEKTNLE-- 2256
Query: 2213 DVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASD 2392
Q K++ + + + + E + K++E E++ A L E +
Sbjct: 2257 --QEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQE-KAKLIEEKTNLEQ 2313
Query: 2393 SPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDL---KRLLLNEKNGLHAXXXX 2563
+ ++ L K K E E + EE +L K L+ EK L
Sbjct: 2314 EKAKPIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEK-- 2371
Query: 2564 XXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDS 2743
A++ + + QE L E+ + L EE + K I+EK +
Sbjct: 2372 ---------AKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTN 2422
Query: 2744 NSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVR 2923
L ++ + +++ + Q +S LL +LE E + + T L E +
Sbjct: 2423 ----LEQEKAKLIEEKTNLEQEKSQLLDQKKNLEEEKQRLETEKAKLIEDKTNLEQEKAQ 2478
Query: 2924 EKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEK---LKEE 3094
E +L +E+ + +++ +K +E+KD +E ++ QI + K L E
Sbjct: 2479 LLEQKKNL-EEEKAKLEEEKAQAQKTIEEKD-------QEIEDLTSQINVKTKDLSLLES 2530
Query: 3095 TENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQL 3274
NN F +++ I ++ L +E +L+N ++ + D L+ + +KLN+++
Sbjct: 2531 DFNNMS--FTNADQSTMISNYEKELSDKNKEINDLQNQLKQMTQNRDELQSKSDKLNEEI 2588
Query: 3275 RCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEK 3454
+ + ++ +L EL ++++K+ +++ L KE
Sbjct: 2589 E--------EKKNIQNLESSLEQKNKENEDLKQQLNKTQGELSAQLQQKTQELENLTKEF 2640
Query: 3455 EELNERLAYTQKAMEQKEAVLVEKLFEGEQKI-LLLESSQSATR----EQTEKYRDLLNS 3619
+L ++ T ++ A L + + E ++KI LLE+ + + ++ + L N+
Sbjct: 2641 NDLKQKSEQTIAQNNEEIANLKKNVAERDKKISQLLENEVNELKKKLSDKENENTSLKNT 2700
Query: 3620 LTE---EHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENL---KEKDLQ 3778
++E E +LKK E+ + +L + TE +K++ + + + + K+KDL+
Sbjct: 2701 ISERENEINNLKKNVSDKENEINQLKNNLTMRETELNKMKDEEVKNAKQIIAQKDKDLE 2759
Score = 105 bits (263), Expect = 1e-19
Identities = 226/1149 (19%), Positives = 453/1149 (39%), Gaps = 57/1149 (4%)
Frame = +2
Query: 377 LKNMNFDLGQDNPGVPGLLEDIRNTK-------DLLDTVESGLYVSNVVSDAVLNGVVSA 535
++N+ Q+ + L E+I+N + D ++ + L + SD + ++A
Sbjct: 2105 IQNLTNTKTQNEEQIKKLQEEIQNLQKQNAEKDDKINEFNAKLSTLSSSSDELTTKFINA 2164
Query: 536 QEEEFKEALAAKDSENFL--LNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLL 709
Q E + + +N + LN+KI DL + LE K ++I E+ +LL
Sbjct: 2165 QNEINQLTKQNNEKDNLISQLNQKISDLENAKSQLENE---KSQLIQEKTNLEQEKAQLL 2221
Query: 710 KDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFR 889
+ +K +++ Q+ E + + + E ++ EK N+ K IE ++ Q +
Sbjct: 2222 E----QKKNLEEEKQKLETEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQE----K 2273
Query: 890 RDEIEDQ-NIKEEIEKQIVETIYVTQIQ-ELGEEHDLLRLESAKYQDEIQSLKDECHAKE 1063
IE++ N+++E K I E + Q + +L EE L E AK +E +L+ E AK
Sbjct: 2274 AKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKPIEEKTNLEQE-KAKL 2332
Query: 1064 MSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSL 1243
+ ++ + + L E N E E N +E I + N K I+
Sbjct: 2333 IEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEK 2392
Query: 1244 AS----RIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTL--KASMEMQCSKLKDE---LE 1396
+ + + + N QE+ + K ++E + S+L D+ LE
Sbjct: 2393 TNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKSQLLDQKKNLE 2452
Query: 1397 EERGKI-SENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAF 1573
EE+ ++ +E + I + E A+ + + ++
Sbjct: 2453 EEKQRLETEKAKLIEDKTNLEQEKAQLLEQKKNLEEEKAKLEEEKAQAQKTIEEK----- 2507
Query: 1574 GSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHI 1753
++E+LT QIN+ + E++ + T + T++SN + E+ K + ++ +
Sbjct: 2508 DQEIEDLTSQINVKTKDLSLLESDFNNMSFTNADQSTMISNYEKELSDKNKEINDLQNQL 2567
Query: 1754 EKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCK 1933
+++ + L S+ L +++ KNIQN + ++++ E+
Sbjct: 2568 KQMTQNR--------DELQSKSDKLNEEIEEK--------KNIQNLESSLEQKNKEN--- 2608
Query: 1934 EELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAE 2113
E+L+ LN ++ + ++K + + + L E L Q E A+
Sbjct: 2609 EDLKQQ-----LNKTQGELSAQLQQKTQELEN----------LTKEFNDLKQKSEQTIAQ 2653
Query: 2114 --EAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPE 2287
E + +L NV K I SQL++ E ++++ K +T +
Sbjct: 2654 NNEEIANLKKNVAERDKKI---SQLLEN----EVNELKKKLSDKENENTSLKNTISEREN 2706
Query: 2288 DLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPK---------EQLLGHFK 2440
++ E + K L + E D ++N + E+L G F
Sbjct: 2707 EINNLKKNVSDKENEINQLKNNLTMRETELNKMKDEEVKNAKQIIAQKDKDLEELNGKFN 2766
Query: 2441 QSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKV 2620
+ L + + EL++ E+I L + + K + ++T +K
Sbjct: 2767 DTNNNLSKAND-ELKQLKEQIESLNKQIEQMK--------CSNNLKESEIKQLTSNLQKY 2817
Query: 2621 LQENKLLPVEEVQRYKMLCVLK---EELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKS 2791
Q K L + Q+ + L +ELQ + +++KE K E L+ K+
Sbjct: 2818 KQALKELNDQNKQKDSQINQLNNEMKELQQTLKQTQEQLKETQDQLKQTQETLATKEKEF 2877
Query: 2792 ADHAQRESHLLKH----IADLEAGITDREIMTSVCSDVLTAL---FVEMVREKEFSLSLA 2950
A A+ ++ LK I DL+ + ++ + L A F ++ ++ E ++
Sbjct: 2878 AKSAEDLNNELKKKQQAIDDLQNNLKQKDAELTDTKQKLEAKTNEFNDLKQKAENEIASL 2937
Query: 2951 TKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIA----ILEKLKEETENNPGRV 3118
KE E + K + K LE L +EN + K +A + + LK E+ENN +
Sbjct: 2938 RKEIEQLKAKLANTSKELEASKSESDLQKKENDKLKVNLAKIAEMYKTLKSESENNSAKS 2997
Query: 3119 FLQSEE-REKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXX 3295
+ ++ +EKI+ + +++ E L N+ + + I+ L ++ + NK L
Sbjct: 2998 NDKIKQMQEKIQNLEIQVEKMKLANENLTNENKLQKETIEMLNKKLLESNKSLTASIKEY 3057
Query: 3296 XXXXXXXXXXXXXXXXISSNLDSM----------QLELRNYNEELKNEIEKKSTDIDLLI 3445
++S + + + E+ + EL + + +K +I+ L
Sbjct: 3058 ETLKRENNLQKDQITKLTSQVQKLTQDFTQLKKEKAEVDSKLNELLDLLAQKDKEIERLK 3117
Query: 3446 KEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLT 3625
E ++LNE K +E+KE ++ + + L E L NSLT
Sbjct: 3118 SENQKLNELYQQITKDLEEKEFLIQSQNNRCIDLLNLTEKKNKEIETLQISNDSLNNSLT 3177
Query: 3626 EEHADLKKQ 3652
+ +L+++
Sbjct: 3178 KSQMELREK 3186
Score = 102 bits (255), Expect = 1e-18
Identities = 239/1234 (19%), Positives = 489/1234 (39%), Gaps = 107/1234 (8%)
Frame = +2
Query: 428 LLEDIRNTKDLLDTVESGLYVSNVVSDAVL-----NGVVSAQEEEFKEALAAKDSENFLL 592
+LE N ++L++ V+ +++ VSD L N VV +E K+ L
Sbjct: 1888 ILELEANNENLINKVKE---LNDSVSDLNLSTENQNSVVKQMTDEIKD-----------L 1933
Query: 593 NKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKL 772
NK+I +L K + ++ ++ K++ I S T ++ + L+K E + + + E+ +
Sbjct: 1934 NKQIHELEVKSENQQKQIEEKDKEIQSLTNTKAQNEELIKKLQEEVENLTNTKNQNEETI 1993
Query: 773 ASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIED-QNIKEEIEKQIV-- 943
+ ++ + K+ I+ Q + QSL + + E +N++E+++
Sbjct: 1994 KNLQEQVQSLTETKNQN----EDLIKKQQEQIQSLTNTKNENEETIKNLQEQVQSLTETK 2049
Query: 944 ----ETIYVTQ--IQELGEEHDLLRLESAKYQDEIQSLKDECHAKE---MSKQAEISKLS 1096
ETI Q +Q L E + K Q+EIQSL + + E Q EI L+
Sbjct: 2050 ATNEETIKKLQGEVQSLTETKATNEEQIKKQQEEIQSLSNTKNENEELIKKLQEEIQNLT 2109
Query: 1097 HT----------LEESIMNSNLESL--------FTAEI---------YENTFRELGDQIS 1195
+T L+E I N ++ F A++ F ++I+
Sbjct: 2110 NTKTQNEEQIKKLQEEIQNLQKQNAEKDDKINEFNAKLSTLSSSSDELTTKFINAQNEIN 2169
Query: 1196 QLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTL---KASMEM 1366
QL K++ I L +I L + ++L+ + L K ++E
Sbjct: 2170 QLTKQNNEKDNLISQLNQKISDLENAKSQLENEKSQLIQEKTNLEQEKAQLLEQKKNLEE 2229
Query: 1367 QCSKLKDE---LEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXX 1537
+ KL+ E LE+E+ K+ E E+ + Q+ + E++ +
Sbjct: 2230 EKQKLETEKTNLEQEKAKLIE--EKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEK 2287
Query: 1538 XXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEK 1717
N+ K + + ++ N+ ++++A+ + + L +K +E+
Sbjct: 2288 AKLIEEKTNLE-QEKAKLIEEKTNL-----EQEKAKPIEEKTNLEQEKAKLIEEKTNLEQ 2341
Query: 1718 SQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVA 1897
+ L ++++E+ + E + L LI + N + K I+ +
Sbjct: 2342 EKAKLIEEKTNLEQEKAKLIEEKTN----LEQEKAKLIEEKTNLEQEK---AKLIEEKTN 2394
Query: 1898 VSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELK 2077
+ QE+ + K LE A L+ + + + K + + + E+ LL++ K
Sbjct: 2395 LEQEKAKLIEEKTNLEQEKAKLI-----EEKTNLEQEKAKLIEEKTNLEQEKSQLLDQKK 2449
Query: 2078 SLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTG 2257
+L ++ + L+ E+A K + + + + +QL+++ K+ E + + + T
Sbjct: 2450 NLEEEKQRLETEKA-KLIEDKTNLEQEK----AQLLEQKKNLEEEKAKLEEEKAQAQKTI 2504
Query: 2258 QAFREP---------PKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASD--SPLR 2404
+ + K +DL S+ + ++ +++ E +D + + L+
Sbjct: 2505 EEKDQEIEDLTSQINVKTKDLSLLESDFNNMSFTNADQSTMISNYEKELSDKNKEINDLQ 2564
Query: 2405 NWPKEQLLGHFKQSFAGLKREYELE-----------LQRKTEEIYDLKRLLLNEKNGLHA 2551
N K+ + K E+E L++K +E DLK+ L + L A
Sbjct: 2565 NQLKQMTQNRDELQSKSDKLNEEIEEKKNIQNLESSLEQKNKENEDLKQQLNKTQGELSA 2624
Query: 2552 XXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIK 2731
+ + T + E + +E L + Q + +I +L K +
Sbjct: 2625 Q-----------LQQKTQELENLTKEFNDLKQKSEQTIA-------QNNEEIANLKKNVA 2666
Query: 2732 EKDSNSKVLAEKLSDALKKSADHAQRESHLLKH--------IADLEAGITDREIMTSVCS 2887
E+D L E + LKK + E+ LK+ I +L+ ++D+E +
Sbjct: 2667 ERDKKISQLLENEVNELKKKLSDKENENTSLKNTISERENEINNLKKNVSDKENEINQLK 2726
Query: 2888 DVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKM---LEDKDKLLCLVGEENKEHK 3058
+ LT E+ + K+ + A ++ + QK L ++ D + L +E K+ K
Sbjct: 2727 NNLTMRETELNKMKDEEVKNA---KQIIAQKDKDLEELNGKFNDTNNNLSKANDELKQLK 2783
Query: 3059 RQIAILEKLKEETE--NNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDI 3232
QI L K E+ + NN L+ E +++ + QAL+E L + + K S I
Sbjct: 2784 EQIESLNKQIEQMKCSNN-----LKESEIKQLTSNLQKYKQALKE---LNDQNKQKDSQI 2835
Query: 3233 DSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEI 3412
+ L E ++L + L+ L + + E E+L NE+
Sbjct: 2836 NQLNNEMKELQQTLK-------QTQEQLKETQDQLKQTQETLATKEKEFAKSAEDLNNEL 2888
Query: 3413 EKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLL----------- 3559
+KK ID L ++ + L T++ +E K + + E +I L
Sbjct: 2889 KKKQQAIDDLQNNLKQKDAELTDTKQKLEAKTNEFNDLKQKAENEIASLRKEIEQLKAKL 2948
Query: 3560 -------ESSQSAT---REQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAM 3709
E+S+S + +++ +K + L + E + LK + + + + K + ++ +
Sbjct: 2949 ANTSKELEASKSESDLQKKENDKLKVNLAKIAEMYKTLKSESENNSAKSNDKIKQMQEKI 3008
Query: 3710 TETKFLKEKLLVSDENL-KEKDLQLRAFEIANSE 3808
+ EK+ +++ENL E LQ E+ N +
Sbjct: 3009 QNLEIQVEKMKLANENLTNENKLQKETIEMLNKK 3042
Score = 101 bits (251), Expect = 3e-18
Identities = 214/1209 (17%), Positives = 479/1209 (39%), Gaps = 40/1209 (3%)
Frame = +2
Query: 284 DGGLDTRKSLETKIAET---LERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTK 454
D L K L+ KI + +++M+ +TA L++ N + + L E I+
Sbjct: 1084 DKTLKEDKILQEKIMQLEAKVQQMKDFNKETAANLESKNLENYNLQDNINSLKEQIQKQN 1143
Query: 455 DLLDTVESGLYVSNVVSDAVLNGVVSAQEEEF---KEALAAKDSENFLLNKKIEDLNHKI 625
D + L + AVL + E + +E ++ + N L K+ + ++I
Sbjct: 1144 DEQANHQKELDERDE-QIAVLQKEIEKYENRYLEQQEVISQEKLNNSNLKLKLNEAENEI 1202
Query: 626 WS--------------LEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETE 763
+ + + Y E + + I++ + +K+ + + ++ + TE
Sbjct: 1203 EKSHIVKQPGELYLSEVPQQISYFENKVKIMNGMITQSNAKIKELESQIEKKNKQIESTE 1262
Query: 764 QKLASRDNEMMHMVLEKDNIILSLH------KQIELQSQNTQSLDCFRRDEIED-----Q 910
L + E+ + + + + SL +++E+ +N ++ + D+++ +
Sbjct: 1263 A-LQKKSRELYRQIRDYEQRLSSLGLTVEQIREMEMTIKNQANIIKAKDDDLKQTKEILE 1321
Query: 911 NIKEEIEKQIVETIYV-----TQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQ 1075
+E+IEK I E++ + T Q + E LL + + D+I +++E +
Sbjct: 1322 YREEQIEKFIAESVSIRDAIETLKQRISELEMLLEKKDKENNDKIAEIQEE-------NR 1374
Query: 1076 AEISKLSHTLEESIMNSN-LESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASR 1252
+ +L+ L+E+ + N LE ++YE E QI Q+ ND+ S I+ ++
Sbjct: 1375 QTLEQLAKQLQEAEEDINVLEG--NCQVYEQEIAEKDKQIEQMTNDIKSLEEVINEQSNT 1432
Query: 1253 IDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEM---QCSKLKDELEEERGKISEN 1423
ID L + +E+ L+ +E + K K+E+E+ + IS+
Sbjct: 1433 IDSLKQDVATKEEEIKQLKQTVSENEEVIKQLQTDIEQKDAEIQKNKEEIEQHKQTISQR 1492
Query: 1424 LERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQ 1603
E I +LQ + + +N+ ++E+L +
Sbjct: 1493 DETIKQLQSEIEQHKQTIADKNN-----------------------------EIEQLKNT 1523
Query: 1604 INIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHE 1783
I+ I + + E+ H T++ + K EIE+ ++ + + + IE+L ++ E
Sbjct: 1524 ISEREETIKQLQNEIEQHKQTMAERDAEIQKNKEEIEQQKQTISNNNNEIEQL-KKTISE 1582
Query: 1784 VDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADL 1963
D+ L I + D S +K +QN++ EQH K+ + A++
Sbjct: 1583 RDAEIEQLKKT----IAERDES-------IKQLQNEI----EQH-----KQTISQRDAEI 1622
Query: 1964 VLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNV 2143
+ ++ V D+ AE+ L+ +L+S E+ + ++ + +N +
Sbjct: 1623 -------------EQLKQTVQQRDQTIAEKEDLIKQLQS-----EIEQHKQTISDKNNEI 1664
Query: 2144 GVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIV 2323
+ ++ + I K ++ Q K R + Q +E
Sbjct: 1665 EQLKQTVNARDEAI---KQLQSEIEQHKQTIAERDAEIQKNKEE---------------- 1705
Query: 2324 EPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEI 2503
E++K +T D ++ E + KQ+ + +R+ E+E ++T +
Sbjct: 1706 ----IEQQK-------QTISQRDETIKQLQNE--IEQHKQTIS--QRDAEIEQLKQTVQQ 1750
Query: 2504 YDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVL 2683
D + EK L +AE + +K +E + QR + + +
Sbjct: 1751 SDQT---IAEKEDLIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQTISQRDESIKQM 1807
Query: 2684 KEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEAGITDR 2863
+ E++ ++ KE + + + +AE+ +++K+ + ++ IA+ +A I
Sbjct: 1808 QSEIEQNKQTIADREKEIEQHKQTIAER-DNSIKQLQEEIEQHKQT---IAERDAEIQKN 1863
Query: 2864 EIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEE 3043
+ ++ + AL E ++ L L + +N+ K L D V +
Sbjct: 1864 KEEIQQKNEAINALTNEGEEKRLKILELEANNENLINKV-----KELNDS------VSDL 1912
Query: 3044 NKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKH 3223
N + Q ++++++ +E ++ ++ E K E Q++ +++ +E + L N
Sbjct: 1913 NLSTENQNSVVKQMTDEIKDLNKQIH---ELEVKSENQQKQIEEKDKEIQSLTNTKAQNE 1969
Query: 3224 SDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELK 3403
I L+EE E L + + S+ E +N NE+L
Sbjct: 1970 ELIKKLQEEVENLTNTKN--------------QNEETIKNLQEQVQSLT-ETKNQNEDLI 2014
Query: 3404 NEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATR 3583
+ +++ + E EE + L +++ + +A E + + + ++ L +++
Sbjct: 2015 KKQQEQIQSLTNTKNENEETIKNLQEQVQSLTETKATNEETIKKLQGEVQSLTETKATNE 2074
Query: 3584 EQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLK 3763
EQ +K ++ + SL+ + ++ EE+Q+ + K L+E++ +
Sbjct: 2075 EQIKKQQEEIQSLSNTKNENEELIKKLQEEIQNLTNTKTQNEEQIKKLQEEIQNLQKQNA 2134
Query: 3764 EKDLQLRAF 3790
EKD ++ F
Sbjct: 2135 EKDDKINEF 2143
Score = 95.1 bits (235), Expect = 2e-16
Identities = 241/1194 (20%), Positives = 471/1194 (39%), Gaps = 107/1194 (8%)
Frame = +2
Query: 536 QEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKD 715
Q E ++A +D N L +K + L K +LEE EE + +TI E+D+ ++D
Sbjct: 2456 QRLETEKAKLIEDKTN-LEQEKAQLLEQKK-NLEEEKAKLEEEKAQAQKTIEEKDQEIED 2513
Query: 716 F-----IHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQI-ELQSQNTQSL 877
+ KDL + + D M EK+ + +K+I +LQ+Q Q
Sbjct: 2514 LTSQINVKTKDLSLLESDFNNMSFTNADQSTMISNYEKE--LSDKNKEINDLQNQLKQMT 2571
Query: 878 DCFRRDEIEDQNIK--EEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDEC 1051
RDE++ ++ K EEIE++ IQ L + E+ + ++ + E
Sbjct: 2572 Q--NRDELQSKSDKLNEEIEEK-------KNIQNLESSLEQKNKENEDLKQQLNKTQGEL 2622
Query: 1052 HAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSY 1231
A+ K E+ L+ + S E T + ++I+ L+ ++ ++
Sbjct: 2623 SAQLQQKTQELENLTKEFNDLKQKS-----------EQTIAQNNEEIANLKKNVAERDKK 2671
Query: 1232 IDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGK 1411
I L L +E N+L+++ + E + + LK+ + E +
Sbjct: 2672 ISQL------LENEVNELKKKL------------------SDKENENTSLKNTISERENE 2707
Query: 1412 ISENLERIS----KLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGS 1579
I+ + +S ++ ++ N L R N +
Sbjct: 2708 INNLKKNVSDKENEINQLKNNLTMRETELNKMKDEEVKNAKQIIAQKD-----------K 2756
Query: 1580 KLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEK 1759
LEEL + N N+ + K E+ + I SL + K + ++ S+++K
Sbjct: 2757 DLEELNGKFNDTNNNLSKANDELKQLKEQIESLNKQIEQMKCSNNLKESEIKQLTSNLQK 2816
Query: 1760 L------VNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNI-QNQVAVSQEQHI 1918
+ND + DS LN+ L + + E L+ + Q Q ++ ++
Sbjct: 2817 YKQALKELNDQNKQKDSQINQLNNEMKELQQTLKQTQEQLKETQDQLKQTQETLATKEKE 2876
Query: 1919 EHQCKEELEGHIA--DLVLNDFSNDI------LSWSRRKEEAVVHDDEFDAERIALLNEL 2074
+ E+L + ++D N++ L+ +++K EA + EF+ + NE+
Sbjct: 2877 FAKSAEDLNNELKKKQQAIDDLQNNLKQKDAELTDTKQKLEAKTN--EFNDLKQKAENEI 2934
Query: 2075 KSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQ---LIQEGKDGEA-SDVQGKSRALR 2242
SL +++E LKA+ A S S + + K E ++ +S
Sbjct: 2935 ASLRKEIEQLKAKLANTSKELEASKSESDLQKKENDKLKVNLAKIAEMYKTLKSESENNS 2994
Query: 2243 RHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQ 2422
S + + K ++L + K+ + T E KL ET + + L K
Sbjct: 2995 AKSNDKIKQMQEKIQNLEIQVEKMKLANENLTNENKLQK----ETIEMLNKKLLESNKS- 3049
Query: 2423 LLGHFKQSFAGLKREYELELQRKTEEIYDLKRLL--LNEKNGLHAXXXXXXXXXXXXVAE 2596
L K+ + LKRE L+ + T+ +++L + A +A+
Sbjct: 3050 LTASIKE-YETLKRENNLQKDQITKLTSQVQKLTQDFTQLKKEKAEVDSKLNELLDLLAQ 3108
Query: 2597 ITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSK----IDSL-LKEIKEKDSNS-KVL 2758
+ E++ EN+ L Q K L + +QS+ ID L L E K K+ + ++
Sbjct: 3109 KDKEIERLKSENQKLNELYQQITKDLEEKEFLIQSQNNRCIDLLNLTEKKNKEIETLQIS 3168
Query: 2759 AEKLSDALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFS 2938
+ L+++L KS + +S LL++ D IT+ S+ ALF + +
Sbjct: 3169 NDSLNNSLTKSQMELREKSTLLENAKDK---ITE--------SNRKLALF-DRLSANSSE 3216
Query: 2939 LSLATKEQETVNQKQMSLRKMLEDKDKLL-----CLVGEEN--KEHKRQI-AILEKLKEE 3094
L+L + + M+L ++ K+K++ ++G E K K ++ A +L+++
Sbjct: 3217 LNLTSSGRGIKKSSSMNLSTDMDSKNKIINQQEQTIIGLEQSLKVSKNEVDATKRELQKQ 3276
Query: 3095 TENNP---GRVFLQSEEREKIEEQKRVLDQALQECEE-----LKNDIQNKHSD-----ID 3235
+NN ++ + E+ K+E + + + + L + ++ + +D NK ++ I
Sbjct: 3277 LQNNKELQNQIKMTKEQFAKLEAKLQSVVKKLNDKDQRIDSLMSSDPNNKQTNQLNKQIS 3336
Query: 3236 SLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRN-------YNE 3394
L E EKL ++ + + + ++++ EL N Y E
Sbjct: 3337 DLNLENEKLKTRVDIITRENQSLKDDLESQKSQKSKLDESCNALKTELINKKSIMDQYKE 3396
Query: 3395 ELKNEIEKKSTDIDLLIKEKEELN-----ERLAYTQ------KAMEQKEAVLVEKLFEGE 3541
+LK +E+ + + + K E N +R +Y + + E K + +K F G+
Sbjct: 3397 KLKELMEQINLKNKQISELKAEFNGSDDEDRKSYVKVIEQEGEITELKVIIDRQKKFVGQ 3456
Query: 3542 QKILL------LESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEV 3703
QK+ + L+ S ++ T+ + + L + +L + L+ E+ +E
Sbjct: 3457 QKMKIADLEKNLKESNDEAQKMTKNLQTTIYELEDRCQNLNQTIEMKNFRLRENEKTIED 3516
Query: 3704 AMTETKFLKEKL--------LVSDENLK---------------EKDLQLRAFEI 3796
E +FLK K+ + SD + K EKD QL +I
Sbjct: 3517 LNKEIEFLKGKIDILSREISMYSDNSSKDNLISKIVSLQKTVSEKDEQLNDAKI 3570
Score = 83.6 bits (205), Expect = 6e-13
Identities = 232/1171 (19%), Positives = 462/1171 (39%), Gaps = 62/1171 (5%)
Frame = +2
Query: 437 DIRNTKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFK---EALAAKDSENFLLNKKIE 607
++R LL+ + + SN L +SA E K S + L+ ++
Sbjct: 3182 ELREKSTLLENAKDKITESN--RKLALFDRLSANSSELNLTSSGRGIKKSSSMNLSTDMD 3239
Query: 608 DLNHKIWSLEETLQYKEEVI-LSSHETISERDRLLKDFIHEKDLMQQRAQETEQ--KLAS 778
N I E+T+ E+ + +S +E + + L K + K+L Q EQ KL +
Sbjct: 3240 SKNKIINQQEQTIIGLEQSLKVSKNEVDATKRELQKQLQNNKELQNQIKMTKEQFAKLEA 3299
Query: 779 RDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYV 958
+ ++ + +KD I SL Q Q +I D N++ E K V+ I
Sbjct: 3300 KLQSVVKKLNDKDQRIDSLMSSDPNNKQTNQL-----NKQISDLNLENEKLKTRVDII-- 3352
Query: 959 TQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLES 1138
E QSLKD+ +++ S+++++ + + L+ ++N
Sbjct: 3353 --------------------TRENQSLKDDLESQK-SQKSKLDESCNALKTELINKK--- 3388
Query: 1139 LFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXX 1318
+ Y+ +EL +QI+ KN I L + + E K +
Sbjct: 3389 -SIMDQYKEKLKELMEQIN-------LKNKQISELKAEFNGSDDEDRKSYVKVIEQEGEI 3440
Query: 1319 XXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISK-LQKMNNELAERSKSQNSI 1495
K + Q K+ D LE+ + ++ ++++K LQ EL +R ++ N
Sbjct: 3441 TELKVIIDRQKKFVGQQKMKIAD-LEKNLKESNDEAQKMTKNLQTTIYELEDRCQNLNQT 3499
Query: 1496 XXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISS 1675
+E+L +I ID E+S + D S
Sbjct: 3500 IEMKNFRLRENE---------------KTIEDLNKEIEFLKGKIDILSREISMYSDNSSK 3544
Query: 1676 ---LQTVLSNQKFEIEKSQ-----KVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLI 1831
+ ++S QK EK + K+ + IE + + + +S L ++ L+
Sbjct: 3545 DNLISKIVSLQKTVSEKDEQLNDAKINSNNSLEIEDKMQQEIDQKNSRIHHLENQMRVLL 3604
Query: 1832 HKVDNSGETLRAFVK-----------NIQNQVAVSQEQHIEHQCK--------EELEGHI 1954
+K + + VK N++N + QE++ + K +E + I
Sbjct: 3605 NKASHENAKEESKVKIDLKKANVKLSNLENDFSSLQEENAALKSKVSKLELVIKEKQSEI 3664
Query: 1955 ADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIA----------LLNELKSLHQDLELL 2104
+++ +NDI S K + +++F E+ + L N+LK+ + +L+
Sbjct: 3665 -NIMAQKNNNDINEISELKSKLRKQNEDFTQEKSSAEKQRSEIDQLTNDLKAKNNELDDS 3723
Query: 2105 KAE-EAVKSLSNNVGVS--------TKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTG 2257
K+E +KS N + K SQL ++ K+ E ++ +++L
Sbjct: 3724 KSEIRILKSKINQLQQDFDAKNHSLQKESEKLSQLEEKMKEKE---LELLNKSLDNDKAA 3780
Query: 2258 QAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHF 2437
+ E + E+L + + K E + K++L L E + K L +
Sbjct: 3781 KEIIEKLQNENLEQS-KQLKKKEKDIEQMKQILNDLNNEQGELKG-------KIMTLQND 3832
Query: 2438 KQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEK 2617
+ +E ++K+EE+ + L +E + + ++ E+
Sbjct: 3833 NEQITKTSQEKFKLNEKKSEELVSMINKLNDEIAEKNKTINGTLLQKEKEITKLKNDLEQ 3892
Query: 2618 VLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSAD 2797
N+ + E + KM L ++L + I+ +E+ EK++ + L EKL +
Sbjct: 3893 SQITNERITNLESEMMKMK-QLNDDLMNDINRYNEELIEKENELQELREKLIQSGNNLQK 3951
Query: 2798 HAQRESH--LLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETV 2971
+S+ L I +LE I D+ ++ +T L+ ++ S S + +
Sbjct: 3952 VTPEQSYFDLQMKITELEDIIKDKNSQLENKTNEITNLYSKLYNTSPPSNSKKPRNTKLE 4011
Query: 2972 NQKQMSLRKMLEDKDK-LLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKI 3148
+K LE+K+K L+ N + + QI KLK ++N F + +
Sbjct: 4012 VEKMRIKMAELENKNKDLIDQNTRMNSDLQAQINQNNKLKRHMKDNENN-FNSQINQLNL 4070
Query: 3149 EEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXX 3328
+ QK V D + + ++ +N+ ++ LRE ++ N+++
Sbjct: 4071 KLQKVVSDYEARLL--ILDNSKNQTQRVNELRERIKQKNEEILSK--------------- 4113
Query: 3329 XXXXXISSNLDSMQLELRNYNEELKNEIE---KKSTDIDLLIKEKEELNERLAYTQKAME 3499
++ +LE N++LKNEIE K++ D+ + +KE + L ++++
Sbjct: 4114 ------EKQINENKLE----NDKLKNEIELSKKQNEDLSNYLSQKEAKIKELERRIQSLD 4163
Query: 3500 QKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQF---LSATE 3670
++ A + ++L + K E ++S+ E+T+ L N+L +E++ LK Q +S +
Sbjct: 4164 EQNAKIEDELNKSINK--NEEINKSSIIERTDLSEQLNNAL-KENSRLKVQIDETVSKIK 4220
Query: 3671 ELQSKERDLEVAMTETKFLKEKLLVSDENLK 3763
EL K+ D+ K + ++L+ E K
Sbjct: 4221 ELCDKDSDI----ARVKLVSDQLIDLSEYCK 4247
>ref|XP_001330650.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121897262|gb|EAY02389.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 1662
Score = 134 bits (337), Expect = 3e-28
Identities = 262/1248 (20%), Positives = 499/1248 (39%), Gaps = 61/1248 (4%)
Frame = +2
Query: 254 ISVTSFIEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLL 433
+S+ S + D SL+ KIAE + +E ++N +L D+P
Sbjct: 75 LSLISQSNARNQNSDLIASLQKKIAEQQQEIE-----------SLNNELWNDDPNESEKD 123
Query: 434 EDIRNTKDLLDTVESGL-YVSNVVSDAVLNGVVSAQEE------EF-------KEALAAK 571
+I+N K + + VS ++A L+ + S E EF KE A
Sbjct: 124 IEIQNLKSQIQKLTKNQPQVSPASNNAELDTLRSQLAEMTQKTKEFSNLEIIIKELRAEN 183
Query: 572 DSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRA 751
D N L +L K ++E + E +ET ++ LL+ I + +
Sbjct: 184 DQLNDELMNDQAELEEKDAEIQELKEQNEGAYKMKYETATKTIELLQKQISASQEISKEN 243
Query: 752 QETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIE 931
+ KLA +D ++ + + +++I +QIE S+N F +E + QN + ++
Sbjct: 244 DALKSKLAEKDKQLQN-YNDMNSLIKEQREQIEKLSKNIDDSSDFAENEKKYQNEIQNLK 302
Query: 932 KQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSK-QAEISKLSHTLE 1108
KQI E ++ D ++ E+ + EI++LK++ KE+ Q +I KL ++
Sbjct: 303 KQIEELQENDNAWGDIDDTDEIKQENENLKKEIENLKNQ--NKEIGNLQLQIEKLKDIIK 360
Query: 1109 ESIMNSNLESLF-TAEIYENTF----------------RELGDQISQLRNDMYSKNSYID 1237
E S+ ESL E EN F +E+ + I +L ++ ++ + D
Sbjct: 361 EK--ESDNESLLQELEKSENNFEIEKIKKENQNLQTKVKEMQETIDELESNAWNDDGN-D 417
Query: 1238 SLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKIS 1417
+ +D L E N L+++ K E + + D +E +I
Sbjct: 418 EIKQNLDKLKQEINNLKKENENLQ-------------KQVEENEENAWNDGNNDEIEEIK 464
Query: 1418 ENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELT 1597
+NLE++ K + ++ E + + I +KL++
Sbjct: 465 QNLEKLQKENENLKKINEEKSNDDEI---------------------------NKLKQEI 497
Query: 1598 DQINIFNSVIDK---KEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVN 1768
++ N + + E E + + IS+L+ K I++ QK +++ E E L N
Sbjct: 498 SELKKENEELQENLWNENENEDNQEEISNLKKENEKLKQNIKELQKQIETNE---ENLWN 554
Query: 1769 DSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEG 1948
++ +++ L S ++N + +E + + EEL+
Sbjct: 555 ENENDLKQKVTELES---------------------EVKNSDKLKEENNKLKKENEELKK 593
Query: 1949 HIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAE--EAV 2122
I DL E V DDE + E L E+ +L ++ E LK E E
Sbjct: 594 EIDDLT----------------ENVWKDDEDNQETEKLKQEINNLKKENEELKKEMDELQ 637
Query: 2123 KSLSNN--VGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLY 2296
+S N S + +L Q+ KD E S+ + + L + Q E +DL
Sbjct: 638 ESTWNESYTEESDELKQKLKELEQKYKDTEKSN-EDLKKLLEQVDNLQKESEKIN-QDLE 695
Query: 2297 TTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYE- 2473
E + E +E ++L + +S ++ KE+L K+ LK+E E
Sbjct: 696 KQIEENQ--ENSDVDENEILK----QKVTELESEVKE--KEKLNEELKKENEDLKKEVEN 747
Query: 2474 -----------LELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKV 2620
E++ K E+ ++ + + E N + + +K+
Sbjct: 748 LQENAWNETENEEIKEKLEKENEILQKQVEENNKTLNDLKQKLSESENEKSVKNSENDKL 807
Query: 2621 LQENKLLPVEEVQR-YKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSAD 2797
Q+ V E++ +K+ LQ K+D L + +++ + K+ +EK K+++D
Sbjct: 808 KQK-----VTEIESDFKISNEKSSNLQQKLDVLSQNLEKLEKEMKISSEKNQKLQKENSD 862
Query: 2798 HAQRESHLLKHIADLEAGIT----DREIMTSVCSDVLTALFVEMVREKEFS--LSLATKE 2959
+ + L K +D + IT ++ + + ++ T EKE TK+
Sbjct: 863 LQNQFTSLQKQNSDNQLKITSLLKEKSELENQLNENSTQNLESNSSEKEIRDLKEKITKQ 922
Query: 2960 QETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEER 3139
E + + + ++K +D + + + K + ++ LK E E +
Sbjct: 923 NEKIKELEEEVKKGYQD-----LWGADSDDDSKEKDEEIKNLKLEIEK------INKNHL 971
Query: 3140 EKI---EEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXX 3310
EKI E++K+ E E+ +N I+ D+ EE KLNK++
Sbjct: 972 EKIGIVEKEKK------NEIEKRENKIKKMRIDLQKKDEEINKLNKEI------------ 1013
Query: 3311 XXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQK 3490
++ D L+ NE +K EI +K KE EE+ ++L+ K
Sbjct: 1014 -SQNKKDEWSTVTFGDDEEISSLKKENERIKQEITEKQ-------KEIEEIQQKLSKFTK 1065
Query: 3491 AMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATE 3670
E+K + + E E+K+ +LE +++ E++ NS +E+ + K++ + E
Sbjct: 1066 ENEEKSSEISLLKKENEEKLSVLEKENEELKQRIEEF----NSFKKENEENKQKIYNLGE 1121
Query: 3671 ELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQ 3814
E + K ++ V E + LK+KL +E +K+K + + +NS+K+
Sbjct: 1122 ETKKKLNEISVLKKENEELKQKLNEINEEMKQKIVDFNE-KFSNSKKE 1168
Score = 88.2 bits (217), Expect = 3e-14
Identities = 190/966 (19%), Positives = 412/966 (42%), Gaps = 29/966 (3%)
Frame = +2
Query: 992 LLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTF 1171
LL+ ++A+ +D ++ + + +A + ++I +L LE+S ++L +A
Sbjct: 15 LLKQKTARIRD-LEKMLSQMNAPSVDNSSKIEELEQQLEDS------KALISA------- 60
Query: 1172 RELGDQISQLRNDMYSKNSYIDSLASR---IDFLSSECNKLQEQXXXXXXXXXXXXXXXX 1342
L + +SQ +N S+ S I +R D ++S K+ EQ
Sbjct: 61 --LQESVSQ-KNAEISRLSLISQSNARNQNSDLIASLQKKIAEQQQEIESLNNELWNDDP 117
Query: 1343 TLKASMEMQCSKLKDELEEERGKISENLERIS------KLQKMNNELAERSKSQNSIXXX 1504
++ +++ LK +++ K+++N ++S +L + ++LAE ++
Sbjct: 118 N-ESEKDIEIQNLKSQIQ----KLTKNQPQVSPASNNAELDTLRSQLAEMTQKTKEFSNL 172
Query: 1505 XXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQT 1684
++ ++ ++L D++ + +++K+AE+ +
Sbjct: 173 E----------------IIIKELRAENDQLNDELMNDQAELEEKDAEIQELKEQNEGAY- 215
Query: 1685 VLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLR 1864
K + E + K ++ + I SA ++ +L K+ + L+
Sbjct: 216 -----KMKYETATKTIELLQKQI------------SASQEISKENDALKSKLAEKDKQLQ 258
Query: 1865 AFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLND--FSNDILSWSRRKEEAVVHDDE 2038
+ N N + Q + IE K + +D N+ + N+I + ++ EE +D+
Sbjct: 259 NY--NDMNSLIKEQREQIEKLSKNIDDS--SDFAENEKKYQNEIQNLKKQIEELQENDNA 314
Query: 2039 FDAERIALLNELKSLHQDLELLKAE-EAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASD 2215
+ +++ + Q+ E LK E E +K+ + +G I +I+E + S
Sbjct: 315 WGD-----IDDTDEIKQENENLKKEIENLKNQNKEIGNLQLQIEKLKDIIKEKESDNESL 369
Query: 2216 VQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDS 2395
+Q ++ + +E ++L T K+ E T ++ L A+ D +D
Sbjct: 370 LQELEKSENNFEIEKIKKEN---QNLQT-----KVKEMQETIDE--LESNAWND-DGNDE 418
Query: 2396 PLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXX 2575
+N K KQ LK+E E LQ++ EE NE+N +
Sbjct: 419 IKQNLDK------LKQEINNLKKENE-NLQKQVEE---------NEENAWN-------DG 455
Query: 2576 XXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKV 2755
+ EI EK+ +EN+ L +++ K +L+ +I L KE +E N +
Sbjct: 456 NNDEIEEIKQNLEKLQKENENL--KKINEEKSNDDEINKLKQEISELKKENEELQEN--L 511
Query: 2756 LAEKLSDALKKSADHAQRESHLLK-HIADLEAGI-TDREIMTSVCSDVLTALFVEMVREK 2929
E ++ ++ + ++E+ LK +I +L+ I T+ E + + + L E+ E
Sbjct: 512 WNENENEDNQEEISNLKKENEKLKQNIKELQKQIETNEENLWNENENDLKQKVTELESEV 571
Query: 2930 EFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEH---KRQIAILEK----LK 3088
+ S L +E + ++ L+K ++D + + E+N+E K++I L+K LK
Sbjct: 572 KNSDKLK-EENNKLKKENEELKKEIDDLTENVWKDDEDNQETEKLKQEINNLKKENEELK 630
Query: 3089 EETENNPGRVFLQS--EEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKL 3262
+E + + +S EE ++++++ + L+Q ++ E+ D++ +D+L++E EK+
Sbjct: 631 KEMDELQESTWNESYTEESDELKQKLKELEQKYKDTEKSNEDLKKLLEQVDNLQKESEKI 690
Query: 3263 NKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLL 3442
N+ L + L+S E NEELK E E +++ L
Sbjct: 691 NQDLEKQIEENQENSDVDENEILKQKV--TELESEVKEKEKLNEELKKENEDLKKEVENL 748
Query: 3443 IK------EKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYR 3604
+ E EE+ E+L + ++++ + L + +QK+ E+ +S + +K
Sbjct: 749 QENAWNETENEEIKEKLEKENEILQKQVEENNKTLNDLKQKLSESENEKSVKNSENDK-- 806
Query: 3605 DLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLR 3784
L ++ +++ F + E+ + ++ L+V + L++++ +S E K + LQ
Sbjct: 807 -----LKQKVTEIESDFKISNEKSSNLQQKLDVLSQNLEKLEKEMKISSE--KNQKLQKE 859
Query: 3785 AFEIAN 3802
++ N
Sbjct: 860 NSDLQN 865
>ref|XP_006789762.1| PREDICTED: CAP-Gly domain-containing linker protein 1-like isoform X4
[Neolamprologus brichardi]
Length = 2220
Score = 131 bits (330), Expect = 2e-27
Identities = 266/1278 (20%), Positives = 511/1278 (39%), Gaps = 113/1278 (8%)
Frame = +2
Query: 302 RKSLETKIAETLERMEIHEGDTANTLK-----NMNFDLG------QDNPGVPGLLEDIRN 448
R+ +T++A ER I E + L+ ++ LG N + LLE+I +
Sbjct: 469 RELEDTRVATVSERSRIMELERDLALRTREVADLQLRLGVQQGSEDSNSTLSPLLEEINS 528
Query: 449 TKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIW 628
+D L + E+ S+ N + AQE+ +A+A + + L+ E L ++
Sbjct: 529 LRDQLASQET----SHQEELGKYNEKLEAQEKIHSDAVAQLQATSVRLSGDKEQLQMRLS 584
Query: 629 SLE-------ETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDN 787
E E + K E ++SH+ E L F + ET+ L
Sbjct: 585 QAEKENADTVELWRSKLEAAVASHQQAMEE--LKVSFSKGAGAQTEELVETKSALEKLKL 642
Query: 788 EMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQI 967
E + E D K + TQ L + + KE +E+ + ++ T+
Sbjct: 643 EHKSALEEADT------KHKAEATTWTQELKALKAQVLSLTEDKERLEESLRSSVEKTEE 696
Query: 968 QELGEEHDLL------RLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSN 1129
Q L E D+L L+ + +++ +L + K+ + ++ ++ L + SN
Sbjct: 697 QHLVEMEDVLGKLHAAELKVKELEEKEATLAQQAQDKDGETKEQMGEMV-ALRSKVAQSN 755
Query: 1130 LESLFTA---EIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXX 1300
E + E ++ + G ++++L + + K + SL ++ + E + L+++
Sbjct: 756 QELVALKAQLEEVQSQGDKQGAKVAELNSQLEGKQQEVLSLQQSLNTVKQEKDTLEQELG 815
Query: 1301 XXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISEN---------LERISKLQKM 1453
T +M+ KL + EE E+ LER K
Sbjct: 816 GLKQKVAESTEEQTTSSKTMQETLEKLSKKEEEYTSLAQESESLKSQLAGLERKIKASDE 875
Query: 1454 NNELAERSKS--QNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQI------- 1606
NE + K+ +N I ++ +LEEL + +
Sbjct: 876 KNEQLSKDKNKLENDISDMMKASGDSSVQLTKMNEELIQKE--RRLEELQNHLAEEKEKV 933
Query: 1607 ----NIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLV--- 1765
+ KE E+ DT + QT ++ + I +K ++ E+ +E+L
Sbjct: 934 ARLNEQLQQEVSHKEHELK---DTRETHQTEINTLQENITTLEKTVKQGETLVEELKASQ 990
Query: 1766 NDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQC-KEEL 1942
SL +V S + K + + + ++ V+ Q + QC EL
Sbjct: 991 EKSLSQVSELHAKEFETLQSQVDKFKQELSSSKDKTQELEKMVSELQPYKEQAQCFSAEL 1050
Query: 1943 EGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAV 2122
+ + D+ S + + E ++F AE+ L +L + L L+
Sbjct: 1051 DSYKHDV--EQLSKKLEKQNLDLENMYKESEDFKAEKGKLEKQLLDVQAKLSALEIIHQE 1108
Query: 2123 KSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYT- 2299
S+ N ++T+ + + Q + A ++HS E K + L
Sbjct: 1109 LSVQNKELLTTRE--------------KLTKRQEELLATKKHSDVSMNEELDKLKSLLLE 1154
Query: 2300 TYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPK-EQLLGHFKQSFAGLKREYEL 2476
+E K ++ +E + L + A+ +DS ++ EQ+ KQ L +YE
Sbjct: 1155 AQTEIKDLKQSKSEYLAQIEELQRQNAEKNDSIRKHQQDIEQIEAKKKQ----LLEDYEK 1210
Query: 2477 ---ELQRKTEEIYDLKRLLLNEKNGL---HAXXXXXXXXXXXXVAEITGKFEKVLQENKL 2638
E R E++ + K L EK+ L AE+ K + + E +
Sbjct: 1211 VCKERNRLEEDLNESKSRLTYEKDNLILERDSARNAKKSLDAKNAELQAKLKSLNLEKED 1270
Query: 2639 LPVEEVQRYKMLCVL---KEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQR 2809
L ++ Q + L K E+ S+I +++++ K + + L KLS KK + R
Sbjct: 1271 LTIKNTQLQALAETLTKEKAEMSSEISAVVEDKKSLQTVKEELQNKLS-ITKKDMESYIR 1329
Query: 2810 ESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMS 2989
E LK I+ + E TS S V + + +++EKE L++ +++T N+K+
Sbjct: 1330 ECEELK-ISKMSLAQMLEEFKTS--SQVTDSERIHLLQEKEDLLAI---QRQTSNKKEEL 1383
Query: 2990 LRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREK----IEEQ 3157
LR++ E K+KL L + + ++ +L +++E + + LQ+ E E + ++
Sbjct: 1384 LREIQELKEKLQVLTEQLTQTREKFEEMLASVEQEKQ----ALRLQNSETEMALHALRKE 1439
Query: 3158 KRVLDQALQE----CEEL---KNDIQNKH----SDIDSLREEQEKLNKQLRCMXXXXXXX 3304
K LD AL++ E L K +++ KH SD +L E++KL +R +
Sbjct: 1440 KMSLDSALEQQNMDYERLAGEKEELEEKHTKAVSDKSALSLERDKLASDIRTISDQLDSF 1499
Query: 3305 XXXXXXXXXXXXXISSNLDSMQLELRNY----------NEELKNEIEKKSTDIDLLIKEK 3454
+S+ L+ QL+ + + N +L+NE++KKS+D ++L K K
Sbjct: 1500 SRTNVNLIQEKNHLSTVLEETQLQKKEFEAKLTSLKLENTDLQNELKKKSSDNEMLEKSK 1559
Query: 3455 EELNERLAYTQKAMEQKEAVL---VEKL-----------FEGEQKILLLESSQSATREQT 3592
EL+E + + E+ + L VEKL E E+K+L L+ ++
Sbjct: 1560 AELSEEHSKLKLNFEKANSELVNQVEKLTEEHKHLQSLQTEAERKVLSLQKENQELVQEI 1619
Query: 3593 EKYRDLLNSLTEEHADLKKQFLSATEE----------LQSKERDLEVAMTETKFLKEKLL 3742
++ + +NS+++ L+ Q + + E L + +L+ A+++ KE+L
Sbjct: 1620 QELKSQINSVSDAKRVLETQLQTESNERSKAVSDHDHLSKQIEELQRALSKVAQEKEELS 1679
Query: 3743 VSDENLKEKDLQLRAFEI 3796
+ N +E Q +AF +
Sbjct: 1680 YNFSNAEE---QKKAFMV 1694
Score = 102 bits (253), Expect = 2e-18
Identities = 254/1250 (20%), Positives = 478/1250 (38%), Gaps = 94/1250 (7%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMN------FDLGQDNPGVPGLL 433
+E E GGL + K+AE+ E TL+ ++ L Q++ + L
Sbjct: 810 LEQELGGL------KQKVAESTEEQTTSSKTMQETLEKLSKKEEEYTSLAQESESLKSQL 863
Query: 434 EDIRNTKDLLDTVESGLY-----VSNVVSDAV-LNGVVSAQEEEFKEALAAKDSENFLLN 595
+ D L + N +SD + +G S Q + E L K+ L
Sbjct: 864 AGLERKIKASDEKNEQLSKDKNKLENDISDMMKASGDSSVQLTKMNEELIQKERRLEELQ 923
Query: 596 KKIEDLNHKIWSLEETLQ----YKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETE 763
+ + K+ L E LQ +KE + + ET L++ I + ++ +
Sbjct: 924 NHLAEEKEKVARLNEQLQQEVSHKEHELKDTRETHQTEINTLQENITTLEKTVKQGETLV 983
Query: 764 QKLASRDNEMMHMVLEKDNIILSLH-KQIE-LQSQNTQSLDCFRRDEIEDQNIKEEIEKQ 937
++L + + + V E LH K+ E LQSQ +D F+++ ++ +E+EK
Sbjct: 984 EELKASQEKSLSQVSE-------LHAKEFETLQSQ----VDKFKQELSSSKDKTQELEKM 1032
Query: 938 IVETI-YVTQIQELGEE-----HDLLRLESA------------KYQDEIQSLKDECHAKE 1063
+ E Y Q Q E HD+ +L K ++ ++ K + +
Sbjct: 1033 VSELQPYKEQAQCFSAELDSYKHDVEQLSKKLEKQNLDLENMYKESEDFKAEKGKLEKQL 1092
Query: 1064 MSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSL 1243
+ QA++S L + + + N E L T E EL ++ ++ S N +D L
Sbjct: 1093 LDVQAKLSALE-IIHQELSVQNKELLTTREKLTKRQEEL---LATKKHSDVSMNEELDKL 1148
Query: 1244 ASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISEN 1423
S + +E L++ S+ + +++E ++ ++ E+
Sbjct: 1149 KSLLLEAQTEIKDLKQSKSEYLAQIEELQRQNAEKNDSIRKHQQDI-EQIEAKKKQLLED 1207
Query: 1424 LERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELT-- 1597
E++ K + E SKS+ + N +KL+ L
Sbjct: 1208 YEKVCKERNRLEEDLNESKSRLTYEKDNLILERDSARNAKKSLDAKNAELQAKLKSLNLE 1267
Query: 1598 --------DQINIFNSVIDKKEAEVSGHLDTI----SSLQTVLSNQKFEIEKSQKVLQSF 1741
Q+ + K++AE+S + + SLQTV + ++ ++K ++S+
Sbjct: 1268 KEDLTIKNTQLQALAETLTKEKAEMSSEISAVVEDKKSLQTVKEELQNKLSITKKDMESY 1327
Query: 1742 ESHIEKL------VNDSLHEVDSAFCSLNS-RFYSLIHKVD---------NSGETLRAFV 1873
E+L + L E ++ +S R + L K D N E L +
Sbjct: 1328 IRECEELKISKMSLAQMLEEFKTSSQVTDSERIHLLQEKEDLLAIQRQTSNKKEELLREI 1387
Query: 1874 KNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAER 2053
+ ++ ++ V EQ Q +E+ E +A + + L + E +H E+
Sbjct: 1388 QELKEKLQVLTEQLT--QTREKFEEMLASV---EQEKQALRLQNSETEMALH--ALRKEK 1440
Query: 2054 IALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSR 2233
++L + L+ + D E L E+ + VS K S L E +D ASD++ S
Sbjct: 1441 MSLDSALEQQNMDYERLAGEKEELEEKHTKAVSDK-----SALSLE-RDKLASDIRTIS- 1493
Query: 2234 ALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWP 2413
D ++S + + +EK L+ + ET
Sbjct: 1494 ------------------DQLDSFSRTNV---NLIQEKNHLSTVLEET------------ 1520
Query: 2414 KEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVA 2593
+ F+ LK E +LQ + ++ +L K L +
Sbjct: 1521 -QLQKKEFEAKLTSLKLE-NTDLQNELKKKSSDNEMLEKSKAELSEEHSKLKLNFEKANS 1578
Query: 2594 EITGKFEKVLQENK-LLPVEEVQRYKMLCVLKE--ELQSKIDSLLKEIKEKDSNSKVLAE 2764
E+ + EK+ +E+K L ++ K+L + KE EL +I L +I +VL
Sbjct: 1579 ELVNQVEKLTEEHKHLQSLQTEAERKVLSLQKENQELVQEIQELKSQINSVSDAKRVLET 1638
Query: 2765 KLSDALKKSADHAQRESHLLKHIADLEAGIT----DREIMTSVCSDVLTALFVEMVREKE 2932
+L + + HL K I +L+ ++ ++E ++ S+ MV +
Sbjct: 1639 QLQTESNERSKAVSDHDHLSKQIEELQRALSKVAQEKEELSYNFSNAEEQKKAFMVDVEA 1698
Query: 2933 FSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAIL-----EKLKEET 3097
L +EQE ++ EDKD+LL + +E RQ+ L E L +
Sbjct: 1699 LKAQLKRQEQEN--------SQLTEDKDQLLSKL----EELGRQMTSLTTEKDELLASQC 1746
Query: 3098 ENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLR 3277
+ G LQ+++ + EQ ++L++ +C ++ + D+ L+ ++E L KQ +
Sbjct: 1747 KLEQGISSLQTDQENWLAEQSKLLEEL--KCLQVSQE--KLQVDVKVLQTDKETLEKQYQ 1802
Query: 3278 CMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLE-------LRNYNEELKNEIEKKSTDID 3436
+++ D++Q+E +R +LKN I K+ +
Sbjct: 1803 DAVAEVSASTAVKEEISSSIAHLTAQKDALQVERNEATQQVRQLESQLKNAISKQLEAAE 1862
Query: 3437 LLIKEKEELNERLAYTQKAMEQKEAV--LVEKLFEGEQKILLLESSQSATREQTEKYRDL 3610
K E L + M+QK V L+++L +Q+ LE+ +++ KY++
Sbjct: 1863 ASGKTAEALEQLTKEKAVLMQQKNEVQSLLDELQTSKQE---LETQLERLKKENSKYQED 1919
Query: 3611 LNSLTEE---HADLKKQFLSATEELQS----KERDLEVAMTETKFLKEKL 3739
LN E+ K EEL++ K + L+ E L E+L
Sbjct: 1920 LNVSKEQLCTETQRSKGLCQEIEELKAAVSVKSQSLQTLQDEKNRLTEEL 1969
Score = 94.0 bits (232), Expect = 5e-16
Identities = 251/1284 (19%), Positives = 497/1284 (38%), Gaps = 132/1284 (10%)
Frame = +2
Query: 305 KSLETKIAETLERMEIHEGDTANTLKNM---NFDLGQDNPGVPGL---LEDIRNTKDLLD 466
K LE K A ++ + +G+T + M + Q N + L LE++++ D
Sbjct: 717 KELEEKEATLAQQAQDKDGETKEQMGEMVALRSKVAQSNQELVALKAQLEEVQSQGD--- 773
Query: 467 TVESGLYVSNVVSDAVLNGVVSAQEEE---FKEALAAKDSENFLLNKKIEDLNHKIWSLE 637
+ G V A LN + +++E +++L E L +++ L K+
Sbjct: 774 --KQGAKV------AELNSQLEGKQQEVLSLQQSLNTVKQEKDTLEQELGGLKQKVAEST 825
Query: 638 ETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKD 817
E + + + E +S+++ E + ++ + E+K+ + D + + +K+
Sbjct: 826 EEQTTSSKTMQETLEKLSKKEEEYTSLAQESESLKSQLAGLERKIKASDEKNEQLSKDKN 885
Query: 818 NIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEI------EKQIVETIYVTQIQELG 979
+ + ++ ++ L + I+ + EE+ EK+ V + QE+
Sbjct: 886 KLENDISDMMKASGDSSVQLTKMNEELIQKERRLEELQNHLAEEKEKVARLNEQLQQEVS 945
Query: 980 EEHDLLRLESAKYQDEIQSLKDECHAKEMS-KQAEISKLSHTLEESIMNSNLESLF-TAE 1153
+ L+ +Q EI +L++ E + KQ E TL E + S +SL +E
Sbjct: 946 HKEHELKDTRETHQTEINTLQENITTLEKTVKQGE------TLVEELKASQEKSLSQVSE 999
Query: 1154 IYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXX 1333
++ F L Q+ + + ++ S L + SE +EQ
Sbjct: 1000 LHAKEFETLQSQVDKFKQELSSSKDKTQELEKMV----SELQPYKEQAQCFSAELDSYKH 1055
Query: 1334 XXXTLKASMEMQCSKLKDELEE------ERGKISENL----ERISKLQKMNNELAERSKS 1483
L +E Q L++ +E E+GK+ + L ++S L+ ++ EL+ ++K
Sbjct: 1056 DVEQLSKKLEKQNLDLENMYKESEDFKAEKGKLEKQLLDVQAKLSALEIIHQELSVQNKE 1115
Query: 1484 QNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLD 1663
+ +N +L++L + + I + S +L
Sbjct: 1116 LLTTREKLTKRQEELLATKKHSDVSMN----EELDKLKSLLLEAQTEIKDLKQSKSEYLA 1171
Query: 1664 TISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDS---LHEVDSAFCSLNSRFYSLIH 1834
I LQ + + I K Q+ ++ E+ ++L+ D E + LN L +
Sbjct: 1172 QIEELQRQNAEKNDSIRKHQQDIEQIEAKKKQLLEDYEKVCKERNRLEEDLNESKSRLTY 1231
Query: 1835 KVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCK-EELEGHIADLVLNDFSNDILSWSRRK 2011
+ DN L + +N ++ E Q K + L DL + + L+ + K
Sbjct: 1232 EKDN----LILERDSARNAKKSLDAKNAELQAKLKSLNLEKEDLTIKNTQLQALAETLTK 1287
Query: 2012 EEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQE 2191
E+A E +E A++ + KSL + + L N + ++ K + + + +E
Sbjct: 1288 EKA-----EMSSEISAVVEDKKSL---------QTVKEELQNKLSITKKDMESYIRECEE 1333
Query: 2192 GKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAF 2371
K + S Q E+ T+ H +EK+ L +
Sbjct: 1334 LKISKMSLAQ-------------------MLEEFKTSSQVTDSERIHLLQEKEDLLAIQR 1374
Query: 2372 ETADASDSPLRNWPK---------EQLLG---HFKQSFAGLKREYE-LELQRKTEEIYDL 2512
+T++ + LR + EQL F++ A +++E + L LQ E+
Sbjct: 1375 QTSNKKEELLREIQELKEKLQVLTEQLTQTREKFEEMLASVEQEKQALRLQNSETEM--A 1432
Query: 2513 KRLLLNEKNGLHAXXXXXXXXXXXXVAE---ITGKFEKVLQENKLLPVEEVQRYKMLCVL 2683
L EK L + E + K K + + L +E + + +
Sbjct: 1433 LHALRKEKMSLDSALEQQNMDYERLAGEKEELEEKHTKAVSDKSALSLERDKLASDIRTI 1492
Query: 2684 KEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIA---DLEAGI 2854
++L S + + I+EK+ S VL E L+K A+ S L++ +L+
Sbjct: 1493 SDQLDSFSRTNVNLIQEKNHLSTVLEET---QLQKKEFEAKLTSLKLENTDLQNELKKKS 1549
Query: 2855 TDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLV 3034
+D E++ ++ L+ ++ E + S + E + ++ L+ + + ++ + +
Sbjct: 1550 SDNEMLEKSKAE-LSEEHSKLKLNFEKANSELVNQVEKLTEEHKHLQSLQTEAERKVLSL 1608
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVF---LQSEEREK-------------IEEQKRV 3166
+EN+E ++I L K + + ++ RV LQ+E E+ IEE +R
Sbjct: 1609 QKENQELVQEIQEL-KSQINSVSDAKRVLETQLQTESNERSKAVSDHDHLSKQIEELQRA 1667
Query: 3167 LDQALQECEELKNDIQNKHS-------DIDSLR--------------EEQEKLNKQLRCM 3283
L + QE EEL + N D+++L+ E++++L +L +
Sbjct: 1668 LSKVAQEKEELSYNFSNAEEQKKAFMVDVEALKAQLKRQEQENSQLTEDKDQLLSKLEEL 1727
Query: 3284 XXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNY-----------------NEELKNEI 3412
+ + S+Q + N+ E+L+ ++
Sbjct: 1728 GRQMTSLTTEKDELLASQCKLEQGISSLQTDQENWLAEQSKLLEELKCLQVSQEKLQVDV 1787
Query: 3413 EKKSTDIDLLIKE--------------KEELNERLAYTQKAMEQKEAVLVEKLFEGEQKI 3550
+ TD + L K+ KEE++ +A+ QK+A+ VE+ E Q++
Sbjct: 1788 KVLQTDKETLEKQYQDAVAEVSASTAVKEEISSSIAH---LTAQKDALQVER-NEATQQV 1843
Query: 3551 LLLE-------SSQSATREQTEKYRDLLNSLTEEHADL---KKQFLSATEELQSKERDLE 3700
LE S Q E + K + L LT+E A L K + S +ELQ+ +++LE
Sbjct: 1844 RQLESQLKNAISKQLEAAEASGKTAEALEQLTKEKAVLMQQKNEVQSLLDELQTSKQELE 1903
Query: 3701 VAM----TETKFLKEKLLVSDENL 3760
+ E +E L VS E L
Sbjct: 1904 TQLERLKKENSKYQEDLNVSKEQL 1927
>ref|XP_006789761.1| PREDICTED: CAP-Gly domain-containing linker protein 1-like isoform X3
[Neolamprologus brichardi]
Length = 2225
Score = 131 bits (330), Expect = 2e-27
Identities = 266/1278 (20%), Positives = 511/1278 (39%), Gaps = 113/1278 (8%)
Frame = +2
Query: 302 RKSLETKIAETLERMEIHEGDTANTLK-----NMNFDLG------QDNPGVPGLLEDIRN 448
R+ +T++A ER I E + L+ ++ LG N + LLE+I +
Sbjct: 469 RELEDTRVATVSERSRIMELERDLALRTREVADLQLRLGVQQGSEDSNSTLSPLLEEINS 528
Query: 449 TKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIW 628
+D L + E+ S+ N + AQE+ +A+A + + L+ E L ++
Sbjct: 529 LRDQLASQET----SHQEELGKYNEKLEAQEKIHSDAVAQLQATSVRLSGDKEQLQMRLS 584
Query: 629 SLE-------ETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDN 787
E E + K E ++SH+ E L F + ET+ L
Sbjct: 585 QAEKENADTVELWRSKLEAAVASHQQAMEE--LKVSFSKGAGAQTEELVETKSALEKLKL 642
Query: 788 EMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQI 967
E + E D K + TQ L + + KE +E+ + ++ T+
Sbjct: 643 EHKSALEEADT------KHKAEATTWTQELKALKAQVLSLTEDKERLEESLRSSVEKTEE 696
Query: 968 QELGEEHDLL------RLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSN 1129
Q L E D+L L+ + +++ +L + K+ + ++ ++ L + SN
Sbjct: 697 QHLVEMEDVLGKLHAAELKVKELEEKEATLAQQAQDKDGETKEQMGEMV-ALRSKVAQSN 755
Query: 1130 LESLFTA---EIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXX 1300
E + E ++ + G ++++L + + K + SL ++ + E + L+++
Sbjct: 756 QELVALKAQLEEVQSQGDKQGAKVAELNSQLEGKQQEVLSLQQSLNTVKQEKDTLEQELG 815
Query: 1301 XXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISEN---------LERISKLQKM 1453
T +M+ KL + EE E+ LER K
Sbjct: 816 GLKQKVAESTEEQTTSSKTMQETLEKLSKKEEEYTSLAQESESLKSQLAGLERKIKASDE 875
Query: 1454 NNELAERSKS--QNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQI------- 1606
NE + K+ +N I ++ +LEEL + +
Sbjct: 876 KNEQLSKDKNKLENDISDMMKASGDSSVQLTKMNEELIQKE--RRLEELQNHLAEEKEKV 933
Query: 1607 ----NIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLV--- 1765
+ KE E+ DT + QT ++ + I +K ++ E+ +E+L
Sbjct: 934 ARLNEQLQQEVSHKEHELK---DTRETHQTEINTLQENITTLEKTVKQGETLVEELKASQ 990
Query: 1766 NDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQC-KEEL 1942
SL +V S + K + + + ++ V+ Q + QC EL
Sbjct: 991 EKSLSQVSELHAKEFETLQSQVDKFKQELSSSKDKTQELEKMVSELQPYKEQAQCFSAEL 1050
Query: 1943 EGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAV 2122
+ + D+ S + + E ++F AE+ L +L + L L+
Sbjct: 1051 DSYKHDV--EQLSKKLEKQNLDLENMYKESEDFKAEKGKLEKQLLDVQAKLSALEIIHQE 1108
Query: 2123 KSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYT- 2299
S+ N ++T+ + + Q + A ++HS E K + L
Sbjct: 1109 LSVQNKELLTTRE--------------KLTKRQEELLATKKHSDVSMNEELDKLKSLLLE 1154
Query: 2300 TYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPK-EQLLGHFKQSFAGLKREYEL 2476
+E K ++ +E + L + A+ +DS ++ EQ+ KQ L +YE
Sbjct: 1155 AQTEIKDLKQSKSEYLAQIEELQRQNAEKNDSIRKHQQDIEQIEAKKKQ----LLEDYEK 1210
Query: 2477 ---ELQRKTEEIYDLKRLLLNEKNGL---HAXXXXXXXXXXXXVAEITGKFEKVLQENKL 2638
E R E++ + K L EK+ L AE+ K + + E +
Sbjct: 1211 VCKERNRLEEDLNESKSRLTYEKDNLILERDSARNAKKSLDAKNAELQAKLKSLNLEKED 1270
Query: 2639 LPVEEVQRYKMLCVL---KEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQR 2809
L ++ Q + L K E+ S+I +++++ K + + L KLS KK + R
Sbjct: 1271 LTIKNTQLQALAETLTKEKAEMSSEISAVVEDKKSLQTVKEELQNKLS-ITKKDMESYIR 1329
Query: 2810 ESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMS 2989
E LK I+ + E TS S V + + +++EKE L++ +++T N+K+
Sbjct: 1330 ECEELK-ISKMSLAQMLEEFKTS--SQVTDSERIHLLQEKEDLLAI---QRQTSNKKEEL 1383
Query: 2990 LRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREK----IEEQ 3157
LR++ E K+KL L + + ++ +L +++E + + LQ+ E E + ++
Sbjct: 1384 LREIQELKEKLQVLTEQLTQTREKFEEMLASVEQEKQ----ALRLQNSETEMALHALRKE 1439
Query: 3158 KRVLDQALQE----CEEL---KNDIQNKH----SDIDSLREEQEKLNKQLRCMXXXXXXX 3304
K LD AL++ E L K +++ KH SD +L E++KL +R +
Sbjct: 1440 KMSLDSALEQQNMDYERLAGEKEELEEKHTKAVSDKSALSLERDKLASDIRTISDQLDSF 1499
Query: 3305 XXXXXXXXXXXXXISSNLDSMQLELRNY----------NEELKNEIEKKSTDIDLLIKEK 3454
+S+ L+ QL+ + + N +L+NE++KKS+D ++L K K
Sbjct: 1500 SRTNVNLIQEKNHLSTVLEETQLQKKEFEAKLTSLKLENTDLQNELKKKSSDNEMLEKSK 1559
Query: 3455 EELNERLAYTQKAMEQKEAVL---VEKL-----------FEGEQKILLLESSQSATREQT 3592
EL+E + + E+ + L VEKL E E+K+L L+ ++
Sbjct: 1560 AELSEEHSKLKLNFEKANSELVNQVEKLTEEHKHLQSLQTEAERKVLSLQKENQELVQEI 1619
Query: 3593 EKYRDLLNSLTEEHADLKKQFLSATEE----------LQSKERDLEVAMTETKFLKEKLL 3742
++ + +NS+++ L+ Q + + E L + +L+ A+++ KE+L
Sbjct: 1620 QELKSQINSVSDAKRVLETQLQTESNERSKAVSDHDHLSKQIEELQRALSKVAQEKEELS 1679
Query: 3743 VSDENLKEKDLQLRAFEI 3796
+ N +E Q +AF +
Sbjct: 1680 YNFSNAEE---QKKAFMV 1694
Score = 102 bits (253), Expect = 2e-18
Identities = 254/1250 (20%), Positives = 478/1250 (38%), Gaps = 94/1250 (7%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMN------FDLGQDNPGVPGLL 433
+E E GGL + K+AE+ E TL+ ++ L Q++ + L
Sbjct: 810 LEQELGGL------KQKVAESTEEQTTSSKTMQETLEKLSKKEEEYTSLAQESESLKSQL 863
Query: 434 EDIRNTKDLLDTVESGLY-----VSNVVSDAV-LNGVVSAQEEEFKEALAAKDSENFLLN 595
+ D L + N +SD + +G S Q + E L K+ L
Sbjct: 864 AGLERKIKASDEKNEQLSKDKNKLENDISDMMKASGDSSVQLTKMNEELIQKERRLEELQ 923
Query: 596 KKIEDLNHKIWSLEETLQ----YKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETE 763
+ + K+ L E LQ +KE + + ET L++ I + ++ +
Sbjct: 924 NHLAEEKEKVARLNEQLQQEVSHKEHELKDTRETHQTEINTLQENITTLEKTVKQGETLV 983
Query: 764 QKLASRDNEMMHMVLEKDNIILSLH-KQIE-LQSQNTQSLDCFRRDEIEDQNIKEEIEKQ 937
++L + + + V E LH K+ E LQSQ +D F+++ ++ +E+EK
Sbjct: 984 EELKASQEKSLSQVSE-------LHAKEFETLQSQ----VDKFKQELSSSKDKTQELEKM 1032
Query: 938 IVETI-YVTQIQELGEE-----HDLLRLESA------------KYQDEIQSLKDECHAKE 1063
+ E Y Q Q E HD+ +L K ++ ++ K + +
Sbjct: 1033 VSELQPYKEQAQCFSAELDSYKHDVEQLSKKLEKQNLDLENMYKESEDFKAEKGKLEKQL 1092
Query: 1064 MSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSL 1243
+ QA++S L + + + N E L T E EL ++ ++ S N +D L
Sbjct: 1093 LDVQAKLSALE-IIHQELSVQNKELLTTREKLTKRQEEL---LATKKHSDVSMNEELDKL 1148
Query: 1244 ASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISEN 1423
S + +E L++ S+ + +++E ++ ++ E+
Sbjct: 1149 KSLLLEAQTEIKDLKQSKSEYLAQIEELQRQNAEKNDSIRKHQQDI-EQIEAKKKQLLED 1207
Query: 1424 LERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELT-- 1597
E++ K + E SKS+ + N +KL+ L
Sbjct: 1208 YEKVCKERNRLEEDLNESKSRLTYEKDNLILERDSARNAKKSLDAKNAELQAKLKSLNLE 1267
Query: 1598 --------DQINIFNSVIDKKEAEVSGHLDTI----SSLQTVLSNQKFEIEKSQKVLQSF 1741
Q+ + K++AE+S + + SLQTV + ++ ++K ++S+
Sbjct: 1268 KEDLTIKNTQLQALAETLTKEKAEMSSEISAVVEDKKSLQTVKEELQNKLSITKKDMESY 1327
Query: 1742 ESHIEKL------VNDSLHEVDSAFCSLNS-RFYSLIHKVD---------NSGETLRAFV 1873
E+L + L E ++ +S R + L K D N E L +
Sbjct: 1328 IRECEELKISKMSLAQMLEEFKTSSQVTDSERIHLLQEKEDLLAIQRQTSNKKEELLREI 1387
Query: 1874 KNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAER 2053
+ ++ ++ V EQ Q +E+ E +A + + L + E +H E+
Sbjct: 1388 QELKEKLQVLTEQLT--QTREKFEEMLASV---EQEKQALRLQNSETEMALH--ALRKEK 1440
Query: 2054 IALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSR 2233
++L + L+ + D E L E+ + VS K S L E +D ASD++ S
Sbjct: 1441 MSLDSALEQQNMDYERLAGEKEELEEKHTKAVSDK-----SALSLE-RDKLASDIRTIS- 1493
Query: 2234 ALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWP 2413
D ++S + + +EK L+ + ET
Sbjct: 1494 ------------------DQLDSFSRTNV---NLIQEKNHLSTVLEET------------ 1520
Query: 2414 KEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVA 2593
+ F+ LK E +LQ + ++ +L K L +
Sbjct: 1521 -QLQKKEFEAKLTSLKLE-NTDLQNELKKKSSDNEMLEKSKAELSEEHSKLKLNFEKANS 1578
Query: 2594 EITGKFEKVLQENK-LLPVEEVQRYKMLCVLKE--ELQSKIDSLLKEIKEKDSNSKVLAE 2764
E+ + EK+ +E+K L ++ K+L + KE EL +I L +I +VL
Sbjct: 1579 ELVNQVEKLTEEHKHLQSLQTEAERKVLSLQKENQELVQEIQELKSQINSVSDAKRVLET 1638
Query: 2765 KLSDALKKSADHAQRESHLLKHIADLEAGIT----DREIMTSVCSDVLTALFVEMVREKE 2932
+L + + HL K I +L+ ++ ++E ++ S+ MV +
Sbjct: 1639 QLQTESNERSKAVSDHDHLSKQIEELQRALSKVAQEKEELSYNFSNAEEQKKAFMVDVEA 1698
Query: 2933 FSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAIL-----EKLKEET 3097
L +EQE ++ EDKD+LL + +E RQ+ L E L +
Sbjct: 1699 LKAQLKRQEQEN--------SQLTEDKDQLLSKL----EELGRQMTSLTTEKDELLASQC 1746
Query: 3098 ENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLR 3277
+ G LQ+++ + EQ ++L++ +C ++ + D+ L+ ++E L KQ +
Sbjct: 1747 KLEQGISSLQTDQENWLAEQSKLLEEL--KCLQVSQE--KLQVDVKVLQTDKETLEKQYQ 1802
Query: 3278 CMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLE-------LRNYNEELKNEIEKKSTDID 3436
+++ D++Q+E +R +LKN I K+ +
Sbjct: 1803 DAVAEVSASTAVKEEISSSIAHLTAQKDALQVERNEATQQVRQLESQLKNAISKQLEAAE 1862
Query: 3437 LLIKEKEELNERLAYTQKAMEQKEAV--LVEKLFEGEQKILLLESSQSATREQTEKYRDL 3610
K E L + M+QK V L+++L +Q+ LE+ +++ KY++
Sbjct: 1863 ASGKTAEALEQLTKEKAVLMQQKNEVQSLLDELQTSKQE---LETQLERLKKENSKYQED 1919
Query: 3611 LNSLTEE---HADLKKQFLSATEELQS----KERDLEVAMTETKFLKEKL 3739
LN E+ K EEL++ K + L+ E L E+L
Sbjct: 1920 LNVSKEQLCTETQRSKGLCQEIEELKAAVSVKSQSLQTLQDEKNRLTEEL 1969
Score = 94.0 bits (232), Expect = 5e-16
Identities = 251/1284 (19%), Positives = 497/1284 (38%), Gaps = 132/1284 (10%)
Frame = +2
Query: 305 KSLETKIAETLERMEIHEGDTANTLKNM---NFDLGQDNPGVPGL---LEDIRNTKDLLD 466
K LE K A ++ + +G+T + M + Q N + L LE++++ D
Sbjct: 717 KELEEKEATLAQQAQDKDGETKEQMGEMVALRSKVAQSNQELVALKAQLEEVQSQGD--- 773
Query: 467 TVESGLYVSNVVSDAVLNGVVSAQEEE---FKEALAAKDSENFLLNKKIEDLNHKIWSLE 637
+ G V A LN + +++E +++L E L +++ L K+
Sbjct: 774 --KQGAKV------AELNSQLEGKQQEVLSLQQSLNTVKQEKDTLEQELGGLKQKVAEST 825
Query: 638 ETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKD 817
E + + + E +S+++ E + ++ + E+K+ + D + + +K+
Sbjct: 826 EEQTTSSKTMQETLEKLSKKEEEYTSLAQESESLKSQLAGLERKIKASDEKNEQLSKDKN 885
Query: 818 NIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEI------EKQIVETIYVTQIQELG 979
+ + ++ ++ L + I+ + EE+ EK+ V + QE+
Sbjct: 886 KLENDISDMMKASGDSSVQLTKMNEELIQKERRLEELQNHLAEEKEKVARLNEQLQQEVS 945
Query: 980 EEHDLLRLESAKYQDEIQSLKDECHAKEMS-KQAEISKLSHTLEESIMNSNLESLF-TAE 1153
+ L+ +Q EI +L++ E + KQ E TL E + S +SL +E
Sbjct: 946 HKEHELKDTRETHQTEINTLQENITTLEKTVKQGE------TLVEELKASQEKSLSQVSE 999
Query: 1154 IYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXX 1333
++ F L Q+ + + ++ S L + SE +EQ
Sbjct: 1000 LHAKEFETLQSQVDKFKQELSSSKDKTQELEKMV----SELQPYKEQAQCFSAELDSYKH 1055
Query: 1334 XXXTLKASMEMQCSKLKDELEE------ERGKISENL----ERISKLQKMNNELAERSKS 1483
L +E Q L++ +E E+GK+ + L ++S L+ ++ EL+ ++K
Sbjct: 1056 DVEQLSKKLEKQNLDLENMYKESEDFKAEKGKLEKQLLDVQAKLSALEIIHQELSVQNKE 1115
Query: 1484 QNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLD 1663
+ +N +L++L + + I + S +L
Sbjct: 1116 LLTTREKLTKRQEELLATKKHSDVSMN----EELDKLKSLLLEAQTEIKDLKQSKSEYLA 1171
Query: 1664 TISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDS---LHEVDSAFCSLNSRFYSLIH 1834
I LQ + + I K Q+ ++ E+ ++L+ D E + LN L +
Sbjct: 1172 QIEELQRQNAEKNDSIRKHQQDIEQIEAKKKQLLEDYEKVCKERNRLEEDLNESKSRLTY 1231
Query: 1835 KVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCK-EELEGHIADLVLNDFSNDILSWSRRK 2011
+ DN L + +N ++ E Q K + L DL + + L+ + K
Sbjct: 1232 EKDN----LILERDSARNAKKSLDAKNAELQAKLKSLNLEKEDLTIKNTQLQALAETLTK 1287
Query: 2012 EEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQE 2191
E+A E +E A++ + KSL + + L N + ++ K + + + +E
Sbjct: 1288 EKA-----EMSSEISAVVEDKKSL---------QTVKEELQNKLSITKKDMESYIRECEE 1333
Query: 2192 GKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAF 2371
K + S Q E+ T+ H +EK+ L +
Sbjct: 1334 LKISKMSLAQ-------------------MLEEFKTSSQVTDSERIHLLQEKEDLLAIQR 1374
Query: 2372 ETADASDSPLRNWPK---------EQLLG---HFKQSFAGLKREYE-LELQRKTEEIYDL 2512
+T++ + LR + EQL F++ A +++E + L LQ E+
Sbjct: 1375 QTSNKKEELLREIQELKEKLQVLTEQLTQTREKFEEMLASVEQEKQALRLQNSETEM--A 1432
Query: 2513 KRLLLNEKNGLHAXXXXXXXXXXXXVAE---ITGKFEKVLQENKLLPVEEVQRYKMLCVL 2683
L EK L + E + K K + + L +E + + +
Sbjct: 1433 LHALRKEKMSLDSALEQQNMDYERLAGEKEELEEKHTKAVSDKSALSLERDKLASDIRTI 1492
Query: 2684 KEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIA---DLEAGI 2854
++L S + + I+EK+ S VL E L+K A+ S L++ +L+
Sbjct: 1493 SDQLDSFSRTNVNLIQEKNHLSTVLEET---QLQKKEFEAKLTSLKLENTDLQNELKKKS 1549
Query: 2855 TDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLV 3034
+D E++ ++ L+ ++ E + S + E + ++ L+ + + ++ + +
Sbjct: 1550 SDNEMLEKSKAE-LSEEHSKLKLNFEKANSELVNQVEKLTEEHKHLQSLQTEAERKVLSL 1608
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVF---LQSEEREK-------------IEEQKRV 3166
+EN+E ++I L K + + ++ RV LQ+E E+ IEE +R
Sbjct: 1609 QKENQELVQEIQEL-KSQINSVSDAKRVLETQLQTESNERSKAVSDHDHLSKQIEELQRA 1667
Query: 3167 LDQALQECEELKNDIQNKHS-------DIDSLR--------------EEQEKLNKQLRCM 3283
L + QE EEL + N D+++L+ E++++L +L +
Sbjct: 1668 LSKVAQEKEELSYNFSNAEEQKKAFMVDVEALKAQLKRQEQENSQLTEDKDQLLSKLEEL 1727
Query: 3284 XXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNY-----------------NEELKNEI 3412
+ + S+Q + N+ E+L+ ++
Sbjct: 1728 GRQMTSLTTEKDELLASQCKLEQGISSLQTDQENWLAEQSKLLEELKCLQVSQEKLQVDV 1787
Query: 3413 EKKSTDIDLLIKE--------------KEELNERLAYTQKAMEQKEAVLVEKLFEGEQKI 3550
+ TD + L K+ KEE++ +A+ QK+A+ VE+ E Q++
Sbjct: 1788 KVLQTDKETLEKQYQDAVAEVSASTAVKEEISSSIAH---LTAQKDALQVER-NEATQQV 1843
Query: 3551 LLLE-------SSQSATREQTEKYRDLLNSLTEEHADL---KKQFLSATEELQSKERDLE 3700
LE S Q E + K + L LT+E A L K + S +ELQ+ +++LE
Sbjct: 1844 RQLESQLKNAISKQLEAAEASGKTAEALEQLTKEKAVLMQQKNEVQSLLDELQTSKQELE 1903
Query: 3701 VAM----TETKFLKEKLLVSDENL 3760
+ E +E L VS E L
Sbjct: 1904 TQLERLKKENSKYQEDLNVSKEQL 1927
Score = 71.2 bits (173), Expect = 3e-09
Identities = 147/699 (21%), Positives = 277/699 (39%), Gaps = 77/699 (11%)
Frame = +2
Query: 428 LLEDIRNTKDLLDTVESGLYVSNVVSDAVLNGV------VSAQEEEFKEALAAKDSENFL 589
LL +I+ K+ L + L + + +L V + Q E + AL A E
Sbjct: 1383 LLREIQELKEKLQVLTEQLTQTREKFEEMLASVEQEKQALRLQNSETEMALHALRKEKMS 1442
Query: 590 LNKKIEDLN---HKIWSLEETLQYKEEVILSSHETIS-ERDRLLKDF------------- 718
L+ +E N ++ +E L+ K +S +S ERD+L D
Sbjct: 1443 LDSALEQQNMDYERLAGEKEELEEKHTKAVSDKSALSLERDKLASDIRTISDQLDSFSRT 1502
Query: 719 ----IHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCF 886
I EK+ + +ET+ + + ++ + LE + L +++ +S + + L+
Sbjct: 1503 NVNLIQEKNHLSTVLEETQLQKKEFEAKLTSLKLENTD----LQNELKKKSSDNEMLEKS 1558
Query: 887 RRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEM 1066
+ E+ +++ K ++ + + V Q+++L EEH +QSL+ E K +
Sbjct: 1559 KA-ELSEEHSKLKLNFEKANSELVNQVEKLTEEHK-----------HLQSLQTEAERKVL 1606
Query: 1067 SKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLA 1246
S Q E +L ++E + S + S+ A+ R L Q+ N+ S D L+
Sbjct: 1607 SLQKENQELVQEIQE--LKSQINSVSDAK------RVLETQLQTESNERSKAVSDHDHLS 1658
Query: 1247 SRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENL 1426
+I+ L +K+ ++ +E ++LK + E+E +++E+
Sbjct: 1659 KQIEELQRALSKVAQEKEELSYNFSNAEEQKKAFMVDVEALKAQLKRQ-EQENSQLTEDK 1717
Query: 1427 ERI-SKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEE---- 1591
+++ SKL+++ ++ + ++ + +A KLE+
Sbjct: 1718 DQLLSKLEELGRQMTSLTTEKDEL-----------------------LASQCKLEQGISS 1754
Query: 1592 -LTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVN 1768
TDQ N AE S L+ + LQ +S +K +++ KVLQ+ + +EK
Sbjct: 1755 LQTDQENWL--------AEQSKLLEELKCLQ--VSQEKLQVDV--KVLQTDKETLEKQYQ 1802
Query: 1769 DSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKE---- 1936
D++ EV SA ++ S I + + L+ ++ A Q + +E Q K
Sbjct: 1803 DAVAEV-SASTAVKEEISSSIAHLTAQKDALQ-----VERNEATQQVRQLESQLKNAISK 1856
Query: 1937 -----ELEGHIADL---------VLNDFSNDILSW---------------SRRKEEAVVH 2029
E G A+ VL N++ S R K+E +
Sbjct: 1857 QLEAAEASGKTAEALEQLTKEKAVLMQQKNEVQSLLDELQTSKQELETQLERLKKENSKY 1916
Query: 2030 DDEFDAERIALLNEL---KSLHQDLELLKAEEAVKSLS--------NNVGVSTKGIHYFS 2176
++ + + L E K L Q++E LKA +VKS S N + H
Sbjct: 1917 QEDLNVSKEQLCTETQRSKGLCQEIEELKAAVSVKSQSLQTLQDEKNRLTEELDNKHRDQ 1976
Query: 2177 QLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDL 2293
+ + KD E S ++ + L++ AF E E L
Sbjct: 1977 SDVVKLKD-ERSKLKKQLEELKQSLPNNAFSESALKEQL 2014
>ref|XP_006789759.1| PREDICTED: CAP-Gly domain-containing linker protein 1-like isoform X1
[Neolamprologus brichardi]
gi|583989095|ref|XP_006789760.1| PREDICTED: CAP-Gly
domain-containing linker protein 1-like isoform X2
[Neolamprologus brichardi]
Length = 2227
Score = 131 bits (330), Expect = 2e-27
Identities = 266/1278 (20%), Positives = 511/1278 (39%), Gaps = 113/1278 (8%)
Frame = +2
Query: 302 RKSLETKIAETLERMEIHEGDTANTLK-----NMNFDLG------QDNPGVPGLLEDIRN 448
R+ +T++A ER I E + L+ ++ LG N + LLE+I +
Sbjct: 469 RELEDTRVATVSERSRIMELERDLALRTREVADLQLRLGVQQGSEDSNSTLSPLLEEINS 528
Query: 449 TKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIW 628
+D L + E+ S+ N + AQE+ +A+A + + L+ E L ++
Sbjct: 529 LRDQLASQET----SHQEELGKYNEKLEAQEKIHSDAVAQLQATSVRLSGDKEQLQMRLS 584
Query: 629 SLE-------ETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDN 787
E E + K E ++SH+ E L F + ET+ L
Sbjct: 585 QAEKENADTVELWRSKLEAAVASHQQAMEE--LKVSFSKGAGAQTEELVETKSALEKLKL 642
Query: 788 EMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQI 967
E + E D K + TQ L + + KE +E+ + ++ T+
Sbjct: 643 EHKSALEEADT------KHKAEATTWTQELKALKAQVLSLTEDKERLEESLRSSVEKTEE 696
Query: 968 QELGEEHDLL------RLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSN 1129
Q L E D+L L+ + +++ +L + K+ + ++ ++ L + SN
Sbjct: 697 QHLVEMEDVLGKLHAAELKVKELEEKEATLAQQAQDKDGETKEQMGEMV-ALRSKVAQSN 755
Query: 1130 LESLFTA---EIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXX 1300
E + E ++ + G ++++L + + K + SL ++ + E + L+++
Sbjct: 756 QELVALKAQLEEVQSQGDKQGAKVAELNSQLEGKQQEVLSLQQSLNTVKQEKDTLEQELG 815
Query: 1301 XXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISEN---------LERISKLQKM 1453
T +M+ KL + EE E+ LER K
Sbjct: 816 GLKQKVAESTEEQTTSSKTMQETLEKLSKKEEEYTSLAQESESLKSQLAGLERKIKASDE 875
Query: 1454 NNELAERSKS--QNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQI------- 1606
NE + K+ +N I ++ +LEEL + +
Sbjct: 876 KNEQLSKDKNKLENDISDMMKASGDSSVQLTKMNEELIQKE--RRLEELQNHLAEEKEKV 933
Query: 1607 ----NIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLV--- 1765
+ KE E+ DT + QT ++ + I +K ++ E+ +E+L
Sbjct: 934 ARLNEQLQQEVSHKEHELK---DTRETHQTEINTLQENITTLEKTVKQGETLVEELKASQ 990
Query: 1766 NDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQC-KEEL 1942
SL +V S + K + + + ++ V+ Q + QC EL
Sbjct: 991 EKSLSQVSELHAKEFETLQSQVDKFKQELSSSKDKTQELEKMVSELQPYKEQAQCFSAEL 1050
Query: 1943 EGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAV 2122
+ + D+ S + + E ++F AE+ L +L + L L+
Sbjct: 1051 DSYKHDV--EQLSKKLEKQNLDLENMYKESEDFKAEKGKLEKQLLDVQAKLSALEIIHQE 1108
Query: 2123 KSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYT- 2299
S+ N ++T+ + + Q + A ++HS E K + L
Sbjct: 1109 LSVQNKELLTTRE--------------KLTKRQEELLATKKHSDVSMNEELDKLKSLLLE 1154
Query: 2300 TYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPK-EQLLGHFKQSFAGLKREYEL 2476
+E K ++ +E + L + A+ +DS ++ EQ+ KQ L +YE
Sbjct: 1155 AQTEIKDLKQSKSEYLAQIEELQRQNAEKNDSIRKHQQDIEQIEAKKKQ----LLEDYEK 1210
Query: 2477 ---ELQRKTEEIYDLKRLLLNEKNGL---HAXXXXXXXXXXXXVAEITGKFEKVLQENKL 2638
E R E++ + K L EK+ L AE+ K + + E +
Sbjct: 1211 VCKERNRLEEDLNESKSRLTYEKDNLILERDSARNAKKSLDAKNAELQAKLKSLNLEKED 1270
Query: 2639 LPVEEVQRYKMLCVL---KEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQR 2809
L ++ Q + L K E+ S+I +++++ K + + L KLS KK + R
Sbjct: 1271 LTIKNTQLQALAETLTKEKAEMSSEISAVVEDKKSLQTVKEELQNKLS-ITKKDMESYIR 1329
Query: 2810 ESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMS 2989
E LK I+ + E TS S V + + +++EKE L++ +++T N+K+
Sbjct: 1330 ECEELK-ISKMSLAQMLEEFKTS--SQVTDSERIHLLQEKEDLLAI---QRQTSNKKEEL 1383
Query: 2990 LRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREK----IEEQ 3157
LR++ E K+KL L + + ++ +L +++E + + LQ+ E E + ++
Sbjct: 1384 LREIQELKEKLQVLTEQLTQTREKFEEMLASVEQEKQ----ALRLQNSETEMALHALRKE 1439
Query: 3158 KRVLDQALQE----CEEL---KNDIQNKH----SDIDSLREEQEKLNKQLRCMXXXXXXX 3304
K LD AL++ E L K +++ KH SD +L E++KL +R +
Sbjct: 1440 KMSLDSALEQQNMDYERLAGEKEELEEKHTKAVSDKSALSLERDKLASDIRTISDQLDSF 1499
Query: 3305 XXXXXXXXXXXXXISSNLDSMQLELRNY----------NEELKNEIEKKSTDIDLLIKEK 3454
+S+ L+ QL+ + + N +L+NE++KKS+D ++L K K
Sbjct: 1500 SRTNVNLIQEKNHLSTVLEETQLQKKEFEAKLTSLKLENTDLQNELKKKSSDNEMLEKSK 1559
Query: 3455 EELNERLAYTQKAMEQKEAVL---VEKL-----------FEGEQKILLLESSQSATREQT 3592
EL+E + + E+ + L VEKL E E+K+L L+ ++
Sbjct: 1560 AELSEEHSKLKLNFEKANSELVNQVEKLTEEHKHLQSLQTEAERKVLSLQKENQELVQEI 1619
Query: 3593 EKYRDLLNSLTEEHADLKKQFLSATEE----------LQSKERDLEVAMTETKFLKEKLL 3742
++ + +NS+++ L+ Q + + E L + +L+ A+++ KE+L
Sbjct: 1620 QELKSQINSVSDAKRVLETQLQTESNERSKAVSDHDHLSKQIEELQRALSKVAQEKEELS 1679
Query: 3743 VSDENLKEKDLQLRAFEI 3796
+ N +E Q +AF +
Sbjct: 1680 YNFSNAEE---QKKAFMV 1694
Score = 102 bits (253), Expect = 2e-18
Identities = 254/1250 (20%), Positives = 478/1250 (38%), Gaps = 94/1250 (7%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMN------FDLGQDNPGVPGLL 433
+E E GGL + K+AE+ E TL+ ++ L Q++ + L
Sbjct: 810 LEQELGGL------KQKVAESTEEQTTSSKTMQETLEKLSKKEEEYTSLAQESESLKSQL 863
Query: 434 EDIRNTKDLLDTVESGLY-----VSNVVSDAV-LNGVVSAQEEEFKEALAAKDSENFLLN 595
+ D L + N +SD + +G S Q + E L K+ L
Sbjct: 864 AGLERKIKASDEKNEQLSKDKNKLENDISDMMKASGDSSVQLTKMNEELIQKERRLEELQ 923
Query: 596 KKIEDLNHKIWSLEETLQ----YKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETE 763
+ + K+ L E LQ +KE + + ET L++ I + ++ +
Sbjct: 924 NHLAEEKEKVARLNEQLQQEVSHKEHELKDTRETHQTEINTLQENITTLEKTVKQGETLV 983
Query: 764 QKLASRDNEMMHMVLEKDNIILSLH-KQIE-LQSQNTQSLDCFRRDEIEDQNIKEEIEKQ 937
++L + + + V E LH K+ E LQSQ +D F+++ ++ +E+EK
Sbjct: 984 EELKASQEKSLSQVSE-------LHAKEFETLQSQ----VDKFKQELSSSKDKTQELEKM 1032
Query: 938 IVETI-YVTQIQELGEE-----HDLLRLESA------------KYQDEIQSLKDECHAKE 1063
+ E Y Q Q E HD+ +L K ++ ++ K + +
Sbjct: 1033 VSELQPYKEQAQCFSAELDSYKHDVEQLSKKLEKQNLDLENMYKESEDFKAEKGKLEKQL 1092
Query: 1064 MSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSL 1243
+ QA++S L + + + N E L T E EL ++ ++ S N +D L
Sbjct: 1093 LDVQAKLSALE-IIHQELSVQNKELLTTREKLTKRQEEL---LATKKHSDVSMNEELDKL 1148
Query: 1244 ASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISEN 1423
S + +E L++ S+ + +++E ++ ++ E+
Sbjct: 1149 KSLLLEAQTEIKDLKQSKSEYLAQIEELQRQNAEKNDSIRKHQQDI-EQIEAKKKQLLED 1207
Query: 1424 LERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELT-- 1597
E++ K + E SKS+ + N +KL+ L
Sbjct: 1208 YEKVCKERNRLEEDLNESKSRLTYEKDNLILERDSARNAKKSLDAKNAELQAKLKSLNLE 1267
Query: 1598 --------DQINIFNSVIDKKEAEVSGHLDTI----SSLQTVLSNQKFEIEKSQKVLQSF 1741
Q+ + K++AE+S + + SLQTV + ++ ++K ++S+
Sbjct: 1268 KEDLTIKNTQLQALAETLTKEKAEMSSEISAVVEDKKSLQTVKEELQNKLSITKKDMESY 1327
Query: 1742 ESHIEKL------VNDSLHEVDSAFCSLNS-RFYSLIHKVD---------NSGETLRAFV 1873
E+L + L E ++ +S R + L K D N E L +
Sbjct: 1328 IRECEELKISKMSLAQMLEEFKTSSQVTDSERIHLLQEKEDLLAIQRQTSNKKEELLREI 1387
Query: 1874 KNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAER 2053
+ ++ ++ V EQ Q +E+ E +A + + L + E +H E+
Sbjct: 1388 QELKEKLQVLTEQLT--QTREKFEEMLASV---EQEKQALRLQNSETEMALH--ALRKEK 1440
Query: 2054 IALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSR 2233
++L + L+ + D E L E+ + VS K S L E +D ASD++ S
Sbjct: 1441 MSLDSALEQQNMDYERLAGEKEELEEKHTKAVSDK-----SALSLE-RDKLASDIRTIS- 1493
Query: 2234 ALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWP 2413
D ++S + + +EK L+ + ET
Sbjct: 1494 ------------------DQLDSFSRTNV---NLIQEKNHLSTVLEET------------ 1520
Query: 2414 KEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVA 2593
+ F+ LK E +LQ + ++ +L K L +
Sbjct: 1521 -QLQKKEFEAKLTSLKLE-NTDLQNELKKKSSDNEMLEKSKAELSEEHSKLKLNFEKANS 1578
Query: 2594 EITGKFEKVLQENK-LLPVEEVQRYKMLCVLKE--ELQSKIDSLLKEIKEKDSNSKVLAE 2764
E+ + EK+ +E+K L ++ K+L + KE EL +I L +I +VL
Sbjct: 1579 ELVNQVEKLTEEHKHLQSLQTEAERKVLSLQKENQELVQEIQELKSQINSVSDAKRVLET 1638
Query: 2765 KLSDALKKSADHAQRESHLLKHIADLEAGIT----DREIMTSVCSDVLTALFVEMVREKE 2932
+L + + HL K I +L+ ++ ++E ++ S+ MV +
Sbjct: 1639 QLQTESNERSKAVSDHDHLSKQIEELQRALSKVAQEKEELSYNFSNAEEQKKAFMVDVEA 1698
Query: 2933 FSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAIL-----EKLKEET 3097
L +EQE ++ EDKD+LL + +E RQ+ L E L +
Sbjct: 1699 LKAQLKRQEQEN--------SQLTEDKDQLLSKL----EELGRQMTSLTTEKDELLASQC 1746
Query: 3098 ENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLR 3277
+ G LQ+++ + EQ ++L++ +C ++ + D+ L+ ++E L KQ +
Sbjct: 1747 KLEQGISSLQTDQENWLAEQSKLLEEL--KCLQVSQE--KLQVDVKVLQTDKETLEKQYQ 1802
Query: 3278 CMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLE-------LRNYNEELKNEIEKKSTDID 3436
+++ D++Q+E +R +LKN I K+ +
Sbjct: 1803 DAVAEVSASTAVKEEISSSIAHLTAQKDALQVERNEATQQVRQLESQLKNAISKQLEAAE 1862
Query: 3437 LLIKEKEELNERLAYTQKAMEQKEAV--LVEKLFEGEQKILLLESSQSATREQTEKYRDL 3610
K E L + M+QK V L+++L +Q+ LE+ +++ KY++
Sbjct: 1863 ASGKTAEALEQLTKEKAVLMQQKNEVQSLLDELQTSKQE---LETQLERLKKENSKYQED 1919
Query: 3611 LNSLTEE---HADLKKQFLSATEELQS----KERDLEVAMTETKFLKEKL 3739
LN E+ K EEL++ K + L+ E L E+L
Sbjct: 1920 LNVSKEQLCTETQRSKGLCQEIEELKAAVSVKSQSLQTLQDEKNRLTEEL 1969
Score = 94.0 bits (232), Expect = 5e-16
Identities = 251/1284 (19%), Positives = 497/1284 (38%), Gaps = 132/1284 (10%)
Frame = +2
Query: 305 KSLETKIAETLERMEIHEGDTANTLKNM---NFDLGQDNPGVPGL---LEDIRNTKDLLD 466
K LE K A ++ + +G+T + M + Q N + L LE++++ D
Sbjct: 717 KELEEKEATLAQQAQDKDGETKEQMGEMVALRSKVAQSNQELVALKAQLEEVQSQGD--- 773
Query: 467 TVESGLYVSNVVSDAVLNGVVSAQEEE---FKEALAAKDSENFLLNKKIEDLNHKIWSLE 637
+ G V A LN + +++E +++L E L +++ L K+
Sbjct: 774 --KQGAKV------AELNSQLEGKQQEVLSLQQSLNTVKQEKDTLEQELGGLKQKVAEST 825
Query: 638 ETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKD 817
E + + + E +S+++ E + ++ + E+K+ + D + + +K+
Sbjct: 826 EEQTTSSKTMQETLEKLSKKEEEYTSLAQESESLKSQLAGLERKIKASDEKNEQLSKDKN 885
Query: 818 NIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEI------EKQIVETIYVTQIQELG 979
+ + ++ ++ L + I+ + EE+ EK+ V + QE+
Sbjct: 886 KLENDISDMMKASGDSSVQLTKMNEELIQKERRLEELQNHLAEEKEKVARLNEQLQQEVS 945
Query: 980 EEHDLLRLESAKYQDEIQSLKDECHAKEMS-KQAEISKLSHTLEESIMNSNLESLF-TAE 1153
+ L+ +Q EI +L++ E + KQ E TL E + S +SL +E
Sbjct: 946 HKEHELKDTRETHQTEINTLQENITTLEKTVKQGE------TLVEELKASQEKSLSQVSE 999
Query: 1154 IYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXX 1333
++ F L Q+ + + ++ S L + SE +EQ
Sbjct: 1000 LHAKEFETLQSQVDKFKQELSSSKDKTQELEKMV----SELQPYKEQAQCFSAELDSYKH 1055
Query: 1334 XXXTLKASMEMQCSKLKDELEE------ERGKISENL----ERISKLQKMNNELAERSKS 1483
L +E Q L++ +E E+GK+ + L ++S L+ ++ EL+ ++K
Sbjct: 1056 DVEQLSKKLEKQNLDLENMYKESEDFKAEKGKLEKQLLDVQAKLSALEIIHQELSVQNKE 1115
Query: 1484 QNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLD 1663
+ +N +L++L + + I + S +L
Sbjct: 1116 LLTTREKLTKRQEELLATKKHSDVSMN----EELDKLKSLLLEAQTEIKDLKQSKSEYLA 1171
Query: 1664 TISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDS---LHEVDSAFCSLNSRFYSLIH 1834
I LQ + + I K Q+ ++ E+ ++L+ D E + LN L +
Sbjct: 1172 QIEELQRQNAEKNDSIRKHQQDIEQIEAKKKQLLEDYEKVCKERNRLEEDLNESKSRLTY 1231
Query: 1835 KVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCK-EELEGHIADLVLNDFSNDILSWSRRK 2011
+ DN L + +N ++ E Q K + L DL + + L+ + K
Sbjct: 1232 EKDN----LILERDSARNAKKSLDAKNAELQAKLKSLNLEKEDLTIKNTQLQALAETLTK 1287
Query: 2012 EEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQE 2191
E+A E +E A++ + KSL + + L N + ++ K + + + +E
Sbjct: 1288 EKA-----EMSSEISAVVEDKKSL---------QTVKEELQNKLSITKKDMESYIRECEE 1333
Query: 2192 GKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAF 2371
K + S Q E+ T+ H +EK+ L +
Sbjct: 1334 LKISKMSLAQ-------------------MLEEFKTSSQVTDSERIHLLQEKEDLLAIQR 1374
Query: 2372 ETADASDSPLRNWPK---------EQLLG---HFKQSFAGLKREYE-LELQRKTEEIYDL 2512
+T++ + LR + EQL F++ A +++E + L LQ E+
Sbjct: 1375 QTSNKKEELLREIQELKEKLQVLTEQLTQTREKFEEMLASVEQEKQALRLQNSETEM--A 1432
Query: 2513 KRLLLNEKNGLHAXXXXXXXXXXXXVAE---ITGKFEKVLQENKLLPVEEVQRYKMLCVL 2683
L EK L + E + K K + + L +E + + +
Sbjct: 1433 LHALRKEKMSLDSALEQQNMDYERLAGEKEELEEKHTKAVSDKSALSLERDKLASDIRTI 1492
Query: 2684 KEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIA---DLEAGI 2854
++L S + + I+EK+ S VL E L+K A+ S L++ +L+
Sbjct: 1493 SDQLDSFSRTNVNLIQEKNHLSTVLEET---QLQKKEFEAKLTSLKLENTDLQNELKKKS 1549
Query: 2855 TDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLV 3034
+D E++ ++ L+ ++ E + S + E + ++ L+ + + ++ + +
Sbjct: 1550 SDNEMLEKSKAE-LSEEHSKLKLNFEKANSELVNQVEKLTEEHKHLQSLQTEAERKVLSL 1608
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVF---LQSEEREK-------------IEEQKRV 3166
+EN+E ++I L K + + ++ RV LQ+E E+ IEE +R
Sbjct: 1609 QKENQELVQEIQEL-KSQINSVSDAKRVLETQLQTESNERSKAVSDHDHLSKQIEELQRA 1667
Query: 3167 LDQALQECEELKNDIQNKHS-------DIDSLR--------------EEQEKLNKQLRCM 3283
L + QE EEL + N D+++L+ E++++L +L +
Sbjct: 1668 LSKVAQEKEELSYNFSNAEEQKKAFMVDVEALKAQLKRQEQENSQLTEDKDQLLSKLEEL 1727
Query: 3284 XXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNY-----------------NEELKNEI 3412
+ + S+Q + N+ E+L+ ++
Sbjct: 1728 GRQMTSLTTEKDELLASQCKLEQGISSLQTDQENWLAEQSKLLEELKCLQVSQEKLQVDV 1787
Query: 3413 EKKSTDIDLLIKE--------------KEELNERLAYTQKAMEQKEAVLVEKLFEGEQKI 3550
+ TD + L K+ KEE++ +A+ QK+A+ VE+ E Q++
Sbjct: 1788 KVLQTDKETLEKQYQDAVAEVSASTAVKEEISSSIAH---LTAQKDALQVER-NEATQQV 1843
Query: 3551 LLLE-------SSQSATREQTEKYRDLLNSLTEEHADL---KKQFLSATEELQSKERDLE 3700
LE S Q E + K + L LT+E A L K + S +ELQ+ +++LE
Sbjct: 1844 RQLESQLKNAISKQLEAAEASGKTAEALEQLTKEKAVLMQQKNEVQSLLDELQTSKQELE 1903
Query: 3701 VAM----TETKFLKEKLLVSDENL 3760
+ E +E L VS E L
Sbjct: 1904 TQLERLKKENSKYQEDLNVSKEQL 1927
>ref|XP_001323236.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121906097|gb|EAY11013.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 2458
Score = 131 bits (329), Expect = 3e-27
Identities = 258/1287 (20%), Positives = 506/1287 (39%), Gaps = 114/1287 (8%)
Frame = +2
Query: 296 DTRKSLETKIAETLERMEIHEG---DTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLD 466
+T +L ++AE +++E E D A ++NM + GL E ++ + ++
Sbjct: 59 ETTATLTNELAECDKKIEEKEKLIEDLAKEIENMKNTTSTASQNDSGLEEVVQEFEQKIE 118
Query: 467 TVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETL 646
T+ES + + D N + Q +++KE +E+ L +K+E++ + S EETL
Sbjct: 119 TLESE---NKTMKDQ--NSELQQQIQQYKELTDKLSTESTELQQKMENIKSEDKSAEETL 173
Query: 647 ------------QYKEEV----------------ILSSHETISERDRLLKDFIHEKDLMQ 742
+ KEE+ + ++ + LK+ + KD +
Sbjct: 174 LQTISDQDIQINKLKEELEQAKLAANSSEQNTNAFAQKEQELNAQITDLKNQLAAKDSLS 233
Query: 743 QRAQETEQKLA---------SRDNEMMHMVLEKD--------------NIILSLHKQIEL 853
+ ++A S +NE + +KD ++ L KQI
Sbjct: 234 DEIASLKAQIAELNQNNSKSSEENEQLKAESQKDASSDDKNSDLSRLKKAVVQLKKQI-- 291
Query: 854 QSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQ 1033
+Q Q ++ + ++ QN E + +E Y +QI E + + L+ E+AK Q E
Sbjct: 292 -AQKDQEINDLKTSNMQLQNFNNETQNVEIEK-YKSQIIEFQKIIESLKAENAKLQTENT 349
Query: 1034 SLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDM 1213
+ D+ Q+EI KL E S + + ++ N EL +QI++L+ +
Sbjct: 350 NTVDKL-------QSEIEKLKQ--ENSELQNQIQENEDGWNDNNNEEELQNQITELQKQL 400
Query: 1214 -YSKNSY---IDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEM----- 1366
+K SY + L ID S + L+++ L+ +
Sbjct: 401 EENKKSYSEETEQLKQIIDDDSKQIEDLKQKLAEAQDHEGNSDSQLAKLQTEKQQLDKKL 460
Query: 1367 -----QCSKLKDELEEERGKISENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXX 1531
KLK + + ++ IS+ E S LQK EL +++ + S
Sbjct: 461 VDVANALRKLKTKNDNDQATISKLNEENSSLQKQIEELKQQTANNASYEAEIQNLKKQLQ 520
Query: 1532 XXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEI 1711
+ K E Q +F + K E+ IS LQ +S++ EI
Sbjct: 521 DLQIQNDDI-------KTENEHLQQEMFE---NNKSEEIEQQKKQISELQKEISSKSSEI 570
Query: 1712 EKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQ 1891
+ +++ IE++ ++ E++ N + D E L+ ++++Q +
Sbjct: 571 QAKNDEIENLNKEIEQIKKEN-QELNEELFQNNEN-----NSNDEEIEKLKTQIQSLQKE 624
Query: 1892 VAVSQEQHIEH-----QCKEELEGHIADLVLNDFSNDILSWSRR-------------KEE 2017
++ +Q+ + + KEELE H ++ N + + S + KE+
Sbjct: 625 ISDLSQQNNNYKSQVEELKEELEKHQSEQDENGWGEENESEELKSENENLKKQIEELKEQ 684
Query: 2018 AVVHDDEFDAER-IALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEG 2194
+D+ E NE + L ++E LK E +N K I + +++
Sbjct: 685 LNQKEDQGQEENGWCNENETEDLKSEIEQLKKENETLKQNNETESLKKQIEELKEQLKQK 744
Query: 2195 KDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAIL-AF 2371
+D QG+ + E + ED + S + T KK+ +
Sbjct: 745 ED------QGQEE--------NGWGEENETEDYKSQIS--ALENEKRTLNKKIKDLANGL 788
Query: 2372 ETADASDSPLRNWPKEQLLGHFKQSFAGLKREYE------LELQRKTEEIYDLKRLLLNE 2533
+T + + L KE + + E+ EL+ + EE+ L E
Sbjct: 789 KTLKSKNEKLEQQLKENANNGNNDNSKDISVEFNETEEKITELEFENEELRRNNESLSEE 848
Query: 2534 KNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVLKEELQSKIDS 2713
K LH + K++ ENK L E + + L+EE S +
Sbjct: 849 KKTLHK------------------QNNKLVSENKTLSDEVSTLREQVEELEEETISTSNE 890
Query: 2714 LLKEIKEKDSNSKVLAEKLSDALKKSADHAQRES-----HLLKHIADLEAGITDREIMTS 2878
L EI+ S V ++L + + E+ H + I + + + +++
Sbjct: 891 LRSEIEHLRSELVVREQELEQTKNNNNNVNNNENNNSNVHSDQSIYEEKISLLKQQLEEL 950
Query: 2879 VCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKML-----------EDKDKLL 3025
S E+ +E ++SL KE E + Q+ L+ L ++K+ +
Sbjct: 951 KQSQSSNNNNEELEKE---NISL-KKEIEDLKQENEGLQNQLFEGGETNENNNQEKEDEI 1006
Query: 3026 CLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKN 3205
+ E +E K+++ E+ KEE N G ++ E E I+ K +++ ++ +E
Sbjct: 1007 HKLKSEIEELKKKLESSEQNKEEENNGWGD---ENTETENIDNLKSEIEELNKKLDESIK 1063
Query: 3206 DIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLELR- 3382
K I+ +++E E+L QL S ++ + +L+
Sbjct: 1064 SNDEKQKKIEEMKQENEELQTQL------------FENNSEEEINKFKSQVEELTQKLQE 1111
Query: 3383 --NYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLFEGEQKILL 3556
NEEL+++ EK++ +ID L K+KEE NE+L QK + + + + + E+
Sbjct: 1112 SNQKNEELQSQTEKQNNEIDDLKKQKEEENEKL---QKEISDLKNEISQLQQKEEENGSD 1168
Query: 3557 LESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLE-VAMTETKFLKE 3733
L+ ++ EK + + L ++ +L+ + EE+ + L+ V+ +++ K+
Sbjct: 1169 LQKQIEVLKQTNEKNDEDIEQLAKQIDELQTEKEKQNEEINDLKSQLQNVSEIKSENEKQ 1228
Query: 3734 KLLVSDENLKEKDLQLRAFEIANSEKQ 3814
K + D + ++LQ + FEI N++++
Sbjct: 1229 KNEIDDLKKENEELQTQLFEIGNNQEK 1255
Score = 130 bits (328), Expect = 3e-27
Identities = 265/1288 (20%), Positives = 529/1288 (41%), Gaps = 134/1288 (10%)
Frame = +2
Query: 305 KSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGL 484
K+L +++ E++E E +T +T + ++ + +++ TK+ + V +
Sbjct: 864 KTLSDEVSTLREQVEELEEETISTSNELRSEIEHLRSELVVREQELEQTKNNNNNVNNNE 923
Query: 485 YV-SNVVSDAVLN----GVVSAQEEEFKEALAAKDS------ENFLLNKKIEDLNHKIWS 631
SNV SD + ++ Q EE K++ ++ ++ EN L K+IEDL +
Sbjct: 924 NNNSNVHSDQSIYEEKISLLKQQLEELKQSQSSNNNNEELEKENISLKKEIEDLKQENEG 983
Query: 632 LEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLE 811
L+ L E ++++ + LK I E ++++ + +EQ +N E
Sbjct: 984 LQNQLFEGGETNENNNQEKEDEIHKLKSEIEE---LKKKLESSEQNKEEENNGWGDENTE 1040
Query: 812 KDNI------ILSLHKQ----IELQSQNTQSLDCFRRDEIE------DQNIKEEIEKQIV 943
+NI I L+K+ I+ + + ++ +++ E + N +EEI K
Sbjct: 1041 TENIDNLKSEIEELNKKLDESIKSNDEKQKKIEEMKQENEELQTQLFENNSEEEINKFKS 1100
Query: 944 ETIYVTQ-IQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEE--- 1111
+ +TQ +QE ++++ L+ ++ K +EI LK + + Q EIS L + + +
Sbjct: 1101 QVEELTQKLQESNQKNEELQSQTEKQNNEIDDLKKQKEEENEKLQKEISDLKNEISQLQQ 1160
Query: 1112 ------SIMNSNLESLF-TAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSS 1270
S + +E L T E + +L QI +L+ + +N I+ L S++ +S
Sbjct: 1161 KEEENGSDLQKQIEVLKQTNEKNDEDIEQLAKQIDELQTEKEKQNEEINDLKSQLQNVSE 1220
Query: 1271 ECNKLQEQXXXXXXXXXXXXXXXXTL-----KASMEMQCSKLKDELEE--------ERGK 1411
++ ++Q L E + KLK E+EE E+ K
Sbjct: 1221 IKSENEKQKNEIDDLKKENEELQTQLFEIGNNQEKEEEIHKLKSEIEELKKKLEESEQNK 1280
Query: 1412 ISENLERIS------------------KLQKMNNELAERSKSQNSIXXXXXXXXXXXXXX 1537
EN++ + +L+K N+EL + +KS +
Sbjct: 1281 EEENIDNLKSENETLKEEIKRLESDNEQLKKQNSELQQENKSLHQQQSKEEEENGWGEEN 1340
Query: 1538 XXXXXXVVNMAFGSKLEELTDQINIFNSVIDKK-----EAEVSGHLDTISSLQTVLSNQK 1702
N + ++EEL +Q+ ++ E E + IS+L+
Sbjct: 1341 ESEELKSENESLKKQIEELKEQLKQKEDQGQEENGWGDENETEDYKSQISALENEKRTLN 1400
Query: 1703 FEIEKSQKVLQSFESHIEKL------------VNDSLHEVDSAFCSLNSRFYSLIHKVDN 1846
+I+ L++ +S EKL ND+ ++ F + I +++
Sbjct: 1401 KKIKDLANGLKTLKSKNEKLEQQLKDINSNNSTNDNSKDISVEFNETEEK----ITELEF 1456
Query: 1847 SGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVV 2026
E LR +N ++S+E+ + +L N +D +S R + E
Sbjct: 1457 ENEELR------RNNESLSEEKKTLQKQNNKLVSE------NKTLSDEVSTLREQVE--- 1501
Query: 2027 HDDEFDAERIALLNELKS----LHQDLELLKAE-EAVKSLSNNVGVS---TKGIHYFSQL 2182
E + E I+ NEL+S L +L L + E E K+ +NNV + +H +
Sbjct: 1502 ---ELEEETISTSNELRSEIEHLRSELVLREQELEQTKNNNNNVNNNENNNSNVHSDQSI 1558
Query: 2183 IQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAI 2362
+E + S ++ + L++ E D K +E E ++L
Sbjct: 1559 YEE----KISLLKQQLEELKQQQQKPFDHEDNNDSDEINKLK--KEIEDLKQENEELQNQ 1612
Query: 2363 LAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRK-------------TEEI 2503
L FE + +++ N KE + K LK++ E Q K TE I
Sbjct: 1613 L-FEGGETNEN--NNQEKEDEIHKLKSEIEELKKKLESSEQNKEEENNGWGDENTETENI 1669
Query: 2504 YDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQRYKMLCVL 2683
+LK + E N + E+ E+ LQE++ EE + + L
Sbjct: 1670 ENLKSEI-EELNKKLNELSKSNDEKQKKIEEL----EQKLQESQNNKDEEEENIEDLKEQ 1724
Query: 2684 KEEL-----------QSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKH 2830
E+L Q +I++L K+I+EK+++ + + E+L K S A+++ +
Sbjct: 1725 LEQLRRDAITKSKQDQEEIENLKKQIEEKEADIEEITEELEQLRKDSITKAKQDQ---EE 1781
Query: 2831 IADLEAGIT-DREIMTSVCSDVLTA---------LFVEMVREKEFSLSLATKEQ---ETV 2971
I L+ I +EI+ ++ +++ L E+ + ++ SL A +Q + +
Sbjct: 1782 IEKLQNEIQKQKEIIDNLNAEIDELGEKEAEHEDLKDELQQLRKDSLQKAKIDQAEIDRL 1841
Query: 2972 NQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIA-ILEKLKEETENNPGRVFLQSEEREKI 3148
N + +L+ LE+ + + ++N++HK + I+EKLK E E+ + EE +
Sbjct: 1842 NAEVSNLKFELENGKENIWGDDDDNEKHKETLTEIIEKLKSEIEDKNSEIEKLEEEISQF 1901
Query: 3149 EEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLR--CMXXXXXXXXXXXXX 3322
E+ V + + EEL ++ +++++ ++ EE KL +QL+
Sbjct: 1902 EDPTEVKQENKKLKEELDQALR-QNAELGNVNEENNKLREQLKQSIDTNELKTLEKKLKE 1960
Query: 3323 XXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQ 3502
+ +L+++Q EL N L + +S +I ++ N++L+ K +E+
Sbjct: 1961 KEEENQKLHDDLNTLQFELNNSIAGLPKINQSESMEIRDEVERLANENKKLSELTKKLEE 2020
Query: 3503 KEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQS 3682
++ LV +L Q+ + + E+ + L +++ +L +Q E+ ++
Sbjct: 2021 EKNFLVSQLENVVQR-----NDYEKELQNVEELKLKLKKAEKDNEELLQQIDELVEQNET 2075
Query: 3683 KERDLEVAMTETKFLKEKLLVSDENLKE 3766
+ + A +E K LK +L ++ KE
Sbjct: 2076 ENHEKSDAESELKSLKAELAKLKDSEKE 2103
Score = 113 bits (282), Expect = 7e-22
Identities = 235/1127 (20%), Positives = 448/1127 (39%), Gaps = 32/1127 (2%)
Frame = +2
Query: 536 QEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKD 715
+ E++K ++A ++E LNKKI+DL + + +L+ + K E L + D
Sbjct: 759 ETEDYKSQISALENEKRTLNKKIKDLANGLKTLKSKNE-KLEQQLKENANNGNND----- 812
Query: 716 FIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRD 895
+ KD+ + ETE+K+ + E + L ++N LS K+ L QN + + +
Sbjct: 813 --NSKDISVE-FNETEEKITELEFE--NEELRRNNESLSEEKKT-LHKQNNKLVSENKTL 866
Query: 896 EIEDQNIKEEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQ 1075
E ++E++E+ ETI S + + EI+ L+ E +E +
Sbjct: 867 SDEVSTLREQVEELEEETIST----------------SNELRSEIEHLRSELVVREQELE 910
Query: 1076 AEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSLASRI 1255
+ ++ NSN+ S IYE L Q+ +L+ S N+ + I
Sbjct: 911 QTKNNNNNVNNNENNNSNVHS--DQSIYEEKISLLKQQLEELKQSQSSNNNNEELEKENI 968
Query: 1256 DFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERI 1435
L E L+++ E + KLK E+EE + K+ + +
Sbjct: 969 S-LKKEIEDLKQENEGLQNQLFEGGETNENNNQEKEDEIHKLKSEIEELKKKLESSEQ-- 1025
Query: 1436 SKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIF 1615
+K ++ N E ++++N + N+ S++EEL +++
Sbjct: 1026 NKEEENNGWGDENTETEN----------------------IDNLK--SEIEELNKKLDES 1061
Query: 1616 NSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLV------NDSL 1777
D+K+ ++ LQT Q FE S++ + F+S +E+L N
Sbjct: 1062 IKSNDEKQKKIEEMKQENEELQT----QLFE-NNSEEEINKFKSQVEELTQKLQESNQKN 1116
Query: 1778 HEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEELEGHIA 1957
E+ S N+ L + + E L+ + +++N++ SQ Q E + +L+ I
Sbjct: 1117 EELQSQTEKQNNEIDDLKKQKEEENEKLQKEISDLKNEI--SQLQQKEEENGSDLQKQIE 1174
Query: 1958 DLVLNDFSND--ILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSL 2131
L + ND I +++ +E ++ + E +N+LKS Q++ +K+E
Sbjct: 1175 VLKQTNEKNDEDIEQLAKQIDELQTEKEKQNEE----INDLKSQLQNVSEIKSEN----- 1225
Query: 2132 SNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSE 2311
E + E D++ ++ L+ + K E+++ SE
Sbjct: 1226 -------------------EKQKNEIDDLKKENEELQTQLF-EIGNNQEKEEEIHKLKSE 1265
Query: 2312 -----GKIVEPHPTEEKKLLAILAFETADASDSPLR-NWPKEQLLGHFKQSFAGLKREYE 2473
K+ E +E++ + L E + R EQL K+ + L++E +
Sbjct: 1266 IEELKKKLEESEQNKEEENIDNLKSENETLKEEIKRLESDNEQL----KKQNSELQQENK 1321
Query: 2474 LELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEE 2653
Q++++E + NE L + ++ K ++ +EN E
Sbjct: 1322 SLHQQQSKEEEENGWGEENESEELKSENESLKKQIEELKEQLKQKEDQGQEENGWGDENE 1381
Query: 2654 VQRYK-MLCVLKEE---LQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHL 2821
+ YK + L+ E L KI L +K S ++ L ++L D ++ + +
Sbjct: 1382 TEDYKSQISALENEKRTLNKKIKDLANGLKTLKSKNEKLEQQLKDINSNNSTN-DNSKDI 1440
Query: 2822 LKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKM 3001
+ E IT+ E E +R SLS K + N K +S K
Sbjct: 1441 SVEFNETEEKITELEFEN------------EELRRNNESLSEEKKTLQKQNNKLVSENKT 1488
Query: 3002 LEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQAL 3181
L D+ L EE +E I+ +L+ E E+ + L+ +E E+ + ++
Sbjct: 1489 LSDEVSTLREQVEELEEET--ISTSNELRSEIEHLRSELVLREQELEQTKNNNNNVNNN- 1545
Query: 3182 QECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLD 3361
+N+ N HSD E+ L +QL + S ++
Sbjct: 1546 ------ENNNSNVHSDQSIYEEKISLLKQQLEELKQQQQKPFDHEDNND------SDEIN 1593
Query: 3362 SMQLE---LRNYNEELKNEI-----------EKKSTDIDLLIKEKEELNERLAYTQKAME 3499
++ E L+ NEEL+N++ ++K +I L E EEL ++L +++ E
Sbjct: 1594 KLKKEIEDLKQENEELQNQLFEGGETNENNNQEKEDEIHKLKSEIEELKKKLESSEQNKE 1653
Query: 3500 QKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQ 3679
++ ++ E E +E+ +S E +K +L S +E Q
Sbjct: 1654 EENNGWGDENTETEN----IENLKSEIEELNKKLNELSKS---------------NDEKQ 1694
Query: 3680 SKERDLEVAMTETKFLKEKLLVSDENLKEKDLQLRAFEIANSEKQYQ 3820
K +LE + E++ K++ + E+LKE+ QLR I S++ +
Sbjct: 1695 KKIEELEQKLQESQNNKDEEEENIEDLKEQLEQLRRDAITKSKQDQE 1741
Score = 81.3 bits (199), Expect = 3e-12
Identities = 147/742 (19%), Positives = 290/742 (39%), Gaps = 21/742 (2%)
Frame = +2
Query: 1616 NSVIDKKEAEVSGHL-----------DTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKL 1762
N ++ + +AE + +T ++L L+ +IE+ +K+++ IE +
Sbjct: 33 NDILKRTQAEYQAQIQKCSDALIEERETTATLTNELAECDKKIEEKEKLIEDLAKEIENM 92
Query: 1763 VNDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCKEEL 1942
N + S +S ++ + + ETL + K +++Q + Q+Q Q KE
Sbjct: 93 KNTT-----STASQNDSGLEEVVQEFEQKIETLESENKTMKDQNSELQQQI--QQYKE-- 143
Query: 1943 EGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAV 2122
L D + + ++K E + +D+ E LL + QD+++ K +E +
Sbjct: 144 --------LTDKLSTESTELQQKMENIKSEDKSAEE--TLLQTISD--QDIQINKLKEEL 191
Query: 2123 KSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTT 2302
+ S + + F+Q QE + + +D++ + A S A L
Sbjct: 192 EQAKLAANSSEQNTNAFAQKEQE-LNAQITDLKNQLAAKDSLSDEIA--------SLKAQ 242
Query: 2303 YSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELEL 2482
+E +EE + L + + A + D K L K++ LK++ +
Sbjct: 243 IAELNQNNSKSSEENEQLKAESQKDASSDD-------KNSDLSRLKKAVVQLKKQ----I 291
Query: 2483 QRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVEEVQR 2662
+K +EI DLK + +N + + E E + EN L E
Sbjct: 292 AQKDQEINDLKTSNMQLQNFNNETQNVEIEKYKSQIIEFQKIIESLKAENAKLQTENTNT 351
Query: 2663 YKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADL 2842
++LQS+I+ L +E E + + + +D E L I +L
Sbjct: 352 V-------DKLQSEIEKLKQENSELQNQIQENEDGWNDN--------NNEEELQNQITEL 396
Query: 2843 EAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKL 3022
+ + + + S ++ L + + ++ E + Q+ L K+ +K +L
Sbjct: 397 QKQLEENKKSYSEETEQLKQIIDDDSKQIEDLKQKLAEAQDHEGNSDSQLAKLQTEKQQL 456
Query: 3023 LCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQKRVLDQALQ------ 3184
+K+ L KLK + +N+ + +EE +++Q L Q
Sbjct: 457 -------DKKLVDVANALRKLKTKNDNDQATISKLNEENSSLQKQIEELKQQTANNASYE 509
Query: 3185 -ECEELKNDIQNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXXXXXXXXXXXISSNLD 3361
E + LK +Q+ D ++ E E L +++ +
Sbjct: 510 AEIQNLKKQLQDLQIQNDDIKTENEHLQQEM------------FENNKSEEIEQQKKQIS 557
Query: 3362 SMQLELRNYNEELK---NEIEKKSTDIDLLIKEKEELNERLAYTQKAMEQKEAVLVEKLF 3532
+Q E+ + + E++ +EIE + +I+ + KE +ELNE L + E +EKL
Sbjct: 558 ELQKEISSKSSEIQAKNDEIENLNKEIEQIKKENQELNEELFQNNENNSNDEE--IEKL- 614
Query: 3533 EGEQKILLLESSQSATREQTEKYRDLLNSLTEEHADLKKQFLSATEELQSKERDLEVAMT 3712
+ +I L+ S +Q Y+ + L EE L+K E +E + E +
Sbjct: 615 --KTQIQSLQKEISDLSQQNNNYKSQVEELKEE---LEKHQSEQDENGWGEENESEELKS 669
Query: 3713 ETKFLKEKLLVSDENLKEKDLQ 3778
E + LK+++ E L +K+ Q
Sbjct: 670 ENENLKKQIEELKEQLNQKEDQ 691
>ref|XP_006789763.1| PREDICTED: CAP-Gly domain-containing linker protein 1-like isoform X5
[Neolamprologus brichardi]
Length = 2192
Score = 130 bits (328), Expect = 3e-27
Identities = 264/1280 (20%), Positives = 510/1280 (39%), Gaps = 105/1280 (8%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAETLER-MEIHEGDTANTLKNMNFDLGQD--NPGVPGLLEDI 442
+ + G L+ E LER + + + A+ + G + N + LLE+I
Sbjct: 432 VSITKGDLEVATVSERSRIMELERDLALRTREVADLQLRLGVQQGSEDSNSTLSPLLEEI 491
Query: 443 RNTKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHK 622
+ +D L + E+ S+ N + AQE+ +A+A + + L+ E L +
Sbjct: 492 NSLRDQLASQET----SHQEELGKYNEKLEAQEKIHSDAVAQLQATSVRLSGDKEQLQMR 547
Query: 623 IWSLE-------ETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASR 781
+ E E + K E ++SH+ E L F + ET+ L
Sbjct: 548 LSQAEKENADTVELWRSKLEAAVASHQQAMEE--LKVSFSKGAGAQTEELVETKSALEKL 605
Query: 782 DNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVT 961
E + E D K + TQ L + + KE +E+ + ++ T
Sbjct: 606 KLEHKSALEEADT------KHKAEATTWTQELKALKAQVLSLTEDKERLEESLRSSVEKT 659
Query: 962 QIQELGEEHDLL------RLESAKYQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMN 1123
+ Q L E D+L L+ + +++ +L + K+ + ++ ++ L +
Sbjct: 660 EEQHLVEMEDVLGKLHAAELKVKELEEKEATLAQQAQDKDGETKEQMGEMV-ALRSKVAQ 718
Query: 1124 SNLESLFTA---EIYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQ 1294
SN E + E ++ + G ++++L + + K + SL ++ + E + L+++
Sbjct: 719 SNQELVALKAQLEEVQSQGDKQGAKVAELNSQLEGKQQEVLSLQQSLNTVKQEKDTLEQE 778
Query: 1295 XXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISEN---------LERISKLQ 1447
T +M+ KL + EE E+ LER K
Sbjct: 779 LGGLKQKVAESTEEQTTSSKTMQETLEKLSKKEEEYTSLAQESESLKSQLAGLERKIKAS 838
Query: 1448 KMNNELAERSKS--QNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQI----- 1606
NE + K+ +N I ++ +LEEL + +
Sbjct: 839 DEKNEQLSKDKNKLENDISDMMKASGDSSVQLTKMNEELIQKE--RRLEELQNHLAEEKE 896
Query: 1607 ------NIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLV- 1765
+ KE E+ DT + QT ++ + I +K ++ E+ +E+L
Sbjct: 897 KVARLNEQLQQEVSHKEHELK---DTRETHQTEINTLQENITTLEKTVKQGETLVEELKA 953
Query: 1766 --NDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQEQHIEHQC-KE 1936
SL +V S + K + + + ++ V+ Q + QC
Sbjct: 954 SQEKSLSQVSELHAKEFETLQSQVDKFKQELSSSKDKTQELEKMVSELQPYKEQAQCFSA 1013
Query: 1937 ELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEE 2116
EL+ + D+ S + + E ++F AE+ L +L + L L+
Sbjct: 1014 ELDSYKHDV--EQLSKKLEKQNLDLENMYKESEDFKAEKGKLEKQLLDVQAKLSALEIIH 1071
Query: 2117 AVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLY 2296
S+ N ++T+ + + Q + A ++HS E K + L
Sbjct: 1072 QELSVQNKELLTTRE--------------KLTKRQEELLATKKHSDVSMNEELDKLKSLL 1117
Query: 2297 T-TYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPK-EQLLGHFKQSFAGLKREY 2470
+E K ++ +E + L + A+ +DS ++ EQ+ KQ L +Y
Sbjct: 1118 LEAQTEIKDLKQSKSEYLAQIEELQRQNAEKNDSIRKHQQDIEQIEAKKKQ----LLEDY 1173
Query: 2471 EL---ELQRKTEEIYDLKRLLLNEKNGL---HAXXXXXXXXXXXXVAEITGKFEKVLQEN 2632
E E R E++ + K L EK+ L AE+ K + + E
Sbjct: 1174 EKVCKERNRLEEDLNESKSRLTYEKDNLILERDSARNAKKSLDAKNAELQAKLKSLNLEK 1233
Query: 2633 KLLPVEEVQRYKMLCVL---KEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHA 2803
+ L ++ Q + L K E+ S+I +++++ K + + L KLS KK +
Sbjct: 1234 EDLTIKNTQLQALAETLTKEKAEMSSEISAVVEDKKSLQTVKEELQNKLS-ITKKDMESY 1292
Query: 2804 QRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQ 2983
RE LK I+ + E TS S V + + +++EKE L++ +++T N+K+
Sbjct: 1293 IRECEELK-ISKMSLAQMLEEFKTS--SQVTDSERIHLLQEKEDLLAI---QRQTSNKKE 1346
Query: 2984 MSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEEREK----IE 3151
LR++ E K+KL L + + ++ +L +++E + + LQ+ E E +
Sbjct: 1347 ELLREIQELKEKLQVLTEQLTQTREKFEEMLASVEQEKQ----ALRLQNSETEMALHALR 1402
Query: 3152 EQKRVLDQALQE----CEEL---KNDIQNKH----SDIDSLREEQEKLNKQLRCMXXXXX 3298
++K LD AL++ E L K +++ KH SD +L E++KL +R +
Sbjct: 1403 KEKMSLDSALEQQNMDYERLAGEKEELEEKHTKAVSDKSALSLERDKLASDIRTISDQLD 1462
Query: 3299 XXXXXXXXXXXXXXXISSNLDSMQLELRNY----------NEELKNEIEKKSTDIDLLIK 3448
+S+ L+ QL+ + + N +L+NE++KKS+D ++L K
Sbjct: 1463 SFSRTNVNLIQEKNHLSTVLEETQLQKKEFEAKLTSLKLENTDLQNELKKKSSDNEMLEK 1522
Query: 3449 EKEELNERLAYTQKAMEQKEAVL---VEKL-----------FEGEQKILLLESSQSATRE 3586
K EL+E + + E+ + L VEKL E E+K+L L+ +
Sbjct: 1523 SKAELSEEHSKLKLNFEKANSELVNQVEKLTEEHKHLQSLQTEAERKVLSLQKENQELVQ 1582
Query: 3587 QTEKYRDLLNSLTEEHADLKKQFLSATEE----------LQSKERDLEVAMTETKFLKEK 3736
+ ++ + +NS+++ L+ Q + + E L + +L+ A+++ KE+
Sbjct: 1583 EIQELKSQINSVSDAKRVLETQLQTESNERSKAVSDHDHLSKQIEELQRALSKVAQEKEE 1642
Query: 3737 LLVSDENLKEKDLQLRAFEI 3796
L + N +E Q +AF +
Sbjct: 1643 LSYNFSNAEE---QKKAFMV 1659
Score = 102 bits (253), Expect = 2e-18
Identities = 254/1250 (20%), Positives = 478/1250 (38%), Gaps = 94/1250 (7%)
Frame = +2
Query: 272 IEVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMN------FDLGQDNPGVPGLL 433
+E E GGL + K+AE+ E TL+ ++ L Q++ + L
Sbjct: 775 LEQELGGL------KQKVAESTEEQTTSSKTMQETLEKLSKKEEEYTSLAQESESLKSQL 828
Query: 434 EDIRNTKDLLDTVESGLY-----VSNVVSDAV-LNGVVSAQEEEFKEALAAKDSENFLLN 595
+ D L + N +SD + +G S Q + E L K+ L
Sbjct: 829 AGLERKIKASDEKNEQLSKDKNKLENDISDMMKASGDSSVQLTKMNEELIQKERRLEELQ 888
Query: 596 KKIEDLNHKIWSLEETLQ----YKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETE 763
+ + K+ L E LQ +KE + + ET L++ I + ++ +
Sbjct: 889 NHLAEEKEKVARLNEQLQQEVSHKEHELKDTRETHQTEINTLQENITTLEKTVKQGETLV 948
Query: 764 QKLASRDNEMMHMVLEKDNIILSLH-KQIE-LQSQNTQSLDCFRRDEIEDQNIKEEIEKQ 937
++L + + + V E LH K+ E LQSQ +D F+++ ++ +E+EK
Sbjct: 949 EELKASQEKSLSQVSE-------LHAKEFETLQSQ----VDKFKQELSSSKDKTQELEKM 997
Query: 938 IVETI-YVTQIQELGEE-----HDLLRLESA------------KYQDEIQSLKDECHAKE 1063
+ E Y Q Q E HD+ +L K ++ ++ K + +
Sbjct: 998 VSELQPYKEQAQCFSAELDSYKHDVEQLSKKLEKQNLDLENMYKESEDFKAEKGKLEKQL 1057
Query: 1064 MSKQAEISKLSHTLEESIMNSNLESLFTAEIYENTFRELGDQISQLRNDMYSKNSYIDSL 1243
+ QA++S L + + + N E L T E EL ++ ++ S N +D L
Sbjct: 1058 LDVQAKLSALE-IIHQELSVQNKELLTTREKLTKRQEEL---LATKKHSDVSMNEELDKL 1113
Query: 1244 ASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISEN 1423
S + +E L++ S+ + +++E ++ ++ E+
Sbjct: 1114 KSLLLEAQTEIKDLKQSKSEYLAQIEELQRQNAEKNDSIRKHQQDI-EQIEAKKKQLLED 1172
Query: 1424 LERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELT-- 1597
E++ K + E SKS+ + N +KL+ L
Sbjct: 1173 YEKVCKERNRLEEDLNESKSRLTYEKDNLILERDSARNAKKSLDAKNAELQAKLKSLNLE 1232
Query: 1598 --------DQINIFNSVIDKKEAEVSGHLDTI----SSLQTVLSNQKFEIEKSQKVLQSF 1741
Q+ + K++AE+S + + SLQTV + ++ ++K ++S+
Sbjct: 1233 KEDLTIKNTQLQALAETLTKEKAEMSSEISAVVEDKKSLQTVKEELQNKLSITKKDMESY 1292
Query: 1742 ESHIEKL------VNDSLHEVDSAFCSLNS-RFYSLIHKVD---------NSGETLRAFV 1873
E+L + L E ++ +S R + L K D N E L +
Sbjct: 1293 IRECEELKISKMSLAQMLEEFKTSSQVTDSERIHLLQEKEDLLAIQRQTSNKKEELLREI 1352
Query: 1874 KNIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAER 2053
+ ++ ++ V EQ Q +E+ E +A + + L + E +H E+
Sbjct: 1353 QELKEKLQVLTEQLT--QTREKFEEMLASV---EQEKQALRLQNSETEMALH--ALRKEK 1405
Query: 2054 IALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSR 2233
++L + L+ + D E L E+ + VS K S L E +D ASD++ S
Sbjct: 1406 MSLDSALEQQNMDYERLAGEKEELEEKHTKAVSDK-----SALSLE-RDKLASDIRTIS- 1458
Query: 2234 ALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWP 2413
D ++S + + +EK L+ + ET
Sbjct: 1459 ------------------DQLDSFSRTNV---NLIQEKNHLSTVLEET------------ 1485
Query: 2414 KEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVA 2593
+ F+ LK E +LQ + ++ +L K L +
Sbjct: 1486 -QLQKKEFEAKLTSLKLE-NTDLQNELKKKSSDNEMLEKSKAELSEEHSKLKLNFEKANS 1543
Query: 2594 EITGKFEKVLQENK-LLPVEEVQRYKMLCVLKE--ELQSKIDSLLKEIKEKDSNSKVLAE 2764
E+ + EK+ +E+K L ++ K+L + KE EL +I L +I +VL
Sbjct: 1544 ELVNQVEKLTEEHKHLQSLQTEAERKVLSLQKENQELVQEIQELKSQINSVSDAKRVLET 1603
Query: 2765 KLSDALKKSADHAQRESHLLKHIADLEAGIT----DREIMTSVCSDVLTALFVEMVREKE 2932
+L + + HL K I +L+ ++ ++E ++ S+ MV +
Sbjct: 1604 QLQTESNERSKAVSDHDHLSKQIEELQRALSKVAQEKEELSYNFSNAEEQKKAFMVDVEA 1663
Query: 2933 FSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAIL-----EKLKEET 3097
L +EQE ++ EDKD+LL + +E RQ+ L E L +
Sbjct: 1664 LKAQLKRQEQEN--------SQLTEDKDQLLSKL----EELGRQMTSLTTEKDELLASQC 1711
Query: 3098 ENNPGRVFLQSEEREKIEEQKRVLDQALQECEELKNDIQNKHSDIDSLREEQEKLNKQLR 3277
+ G LQ+++ + EQ ++L++ +C ++ + D+ L+ ++E L KQ +
Sbjct: 1712 KLEQGISSLQTDQENWLAEQSKLLEEL--KCLQVSQE--KLQVDVKVLQTDKETLEKQYQ 1767
Query: 3278 CMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLE-------LRNYNEELKNEIEKKSTDID 3436
+++ D++Q+E +R +LKN I K+ +
Sbjct: 1768 DAVAEVSASTAVKEEISSSIAHLTAQKDALQVERNEATQQVRQLESQLKNAISKQLEAAE 1827
Query: 3437 LLIKEKEELNERLAYTQKAMEQKEAV--LVEKLFEGEQKILLLESSQSATREQTEKYRDL 3610
K E L + M+QK V L+++L +Q+ LE+ +++ KY++
Sbjct: 1828 ASGKTAEALEQLTKEKAVLMQQKNEVQSLLDELQTSKQE---LETQLERLKKENSKYQED 1884
Query: 3611 LNSLTEE---HADLKKQFLSATEELQS----KERDLEVAMTETKFLKEKL 3739
LN E+ K EEL++ K + L+ E L E+L
Sbjct: 1885 LNVSKEQLCTETQRSKGLCQEIEELKAAVSVKSQSLQTLQDEKNRLTEEL 1934
Score = 94.0 bits (232), Expect = 5e-16
Identities = 251/1284 (19%), Positives = 497/1284 (38%), Gaps = 132/1284 (10%)
Frame = +2
Query: 305 KSLETKIAETLERMEIHEGDTANTLKNM---NFDLGQDNPGVPGL---LEDIRNTKDLLD 466
K LE K A ++ + +G+T + M + Q N + L LE++++ D
Sbjct: 682 KELEEKEATLAQQAQDKDGETKEQMGEMVALRSKVAQSNQELVALKAQLEEVQSQGD--- 738
Query: 467 TVESGLYVSNVVSDAVLNGVVSAQEEE---FKEALAAKDSENFLLNKKIEDLNHKIWSLE 637
+ G V A LN + +++E +++L E L +++ L K+
Sbjct: 739 --KQGAKV------AELNSQLEGKQQEVLSLQQSLNTVKQEKDTLEQELGGLKQKVAEST 790
Query: 638 ETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKD 817
E + + + E +S+++ E + ++ + E+K+ + D + + +K+
Sbjct: 791 EEQTTSSKTMQETLEKLSKKEEEYTSLAQESESLKSQLAGLERKIKASDEKNEQLSKDKN 850
Query: 818 NIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEI------EKQIVETIYVTQIQELG 979
+ + ++ ++ L + I+ + EE+ EK+ V + QE+
Sbjct: 851 KLENDISDMMKASGDSSVQLTKMNEELIQKERRLEELQNHLAEEKEKVARLNEQLQQEVS 910
Query: 980 EEHDLLRLESAKYQDEIQSLKDECHAKEMS-KQAEISKLSHTLEESIMNSNLESLF-TAE 1153
+ L+ +Q EI +L++ E + KQ E TL E + S +SL +E
Sbjct: 911 HKEHELKDTRETHQTEINTLQENITTLEKTVKQGE------TLVEELKASQEKSLSQVSE 964
Query: 1154 IYENTFRELGDQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXX 1333
++ F L Q+ + + ++ S L + SE +EQ
Sbjct: 965 LHAKEFETLQSQVDKFKQELSSSKDKTQELEKMV----SELQPYKEQAQCFSAELDSYKH 1020
Query: 1334 XXXTLKASMEMQCSKLKDELEE------ERGKISENL----ERISKLQKMNNELAERSKS 1483
L +E Q L++ +E E+GK+ + L ++S L+ ++ EL+ ++K
Sbjct: 1021 DVEQLSKKLEKQNLDLENMYKESEDFKAEKGKLEKQLLDVQAKLSALEIIHQELSVQNKE 1080
Query: 1484 QNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLD 1663
+ +N +L++L + + I + S +L
Sbjct: 1081 LLTTREKLTKRQEELLATKKHSDVSMN----EELDKLKSLLLEAQTEIKDLKQSKSEYLA 1136
Query: 1664 TISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDS---LHEVDSAFCSLNSRFYSLIH 1834
I LQ + + I K Q+ ++ E+ ++L+ D E + LN L +
Sbjct: 1137 QIEELQRQNAEKNDSIRKHQQDIEQIEAKKKQLLEDYEKVCKERNRLEEDLNESKSRLTY 1196
Query: 1835 KVDNSGETLRAFVKNIQNQVAVSQEQHIEHQCK-EELEGHIADLVLNDFSNDILSWSRRK 2011
+ DN L + +N ++ E Q K + L DL + + L+ + K
Sbjct: 1197 EKDN----LILERDSARNAKKSLDAKNAELQAKLKSLNLEKEDLTIKNTQLQALAETLTK 1252
Query: 2012 EEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQE 2191
E+A E +E A++ + KSL + + L N + ++ K + + + +E
Sbjct: 1253 EKA-----EMSSEISAVVEDKKSL---------QTVKEELQNKLSITKKDMESYIRECEE 1298
Query: 2192 GKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAF 2371
K + S Q E+ T+ H +EK+ L +
Sbjct: 1299 LKISKMSLAQ-------------------MLEEFKTSSQVTDSERIHLLQEKEDLLAIQR 1339
Query: 2372 ETADASDSPLRNWPK---------EQLLG---HFKQSFAGLKREYE-LELQRKTEEIYDL 2512
+T++ + LR + EQL F++ A +++E + L LQ E+
Sbjct: 1340 QTSNKKEELLREIQELKEKLQVLTEQLTQTREKFEEMLASVEQEKQALRLQNSETEM--A 1397
Query: 2513 KRLLLNEKNGLHAXXXXXXXXXXXXVAE---ITGKFEKVLQENKLLPVEEVQRYKMLCVL 2683
L EK L + E + K K + + L +E + + +
Sbjct: 1398 LHALRKEKMSLDSALEQQNMDYERLAGEKEELEEKHTKAVSDKSALSLERDKLASDIRTI 1457
Query: 2684 KEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIA---DLEAGI 2854
++L S + + I+EK+ S VL E L+K A+ S L++ +L+
Sbjct: 1458 SDQLDSFSRTNVNLIQEKNHLSTVLEET---QLQKKEFEAKLTSLKLENTDLQNELKKKS 1514
Query: 2855 TDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLCLV 3034
+D E++ ++ L+ ++ E + S + E + ++ L+ + + ++ + +
Sbjct: 1515 SDNEMLEKSKAE-LSEEHSKLKLNFEKANSELVNQVEKLTEEHKHLQSLQTEAERKVLSL 1573
Query: 3035 GEENKEHKRQIAILEKLKEETENNPGRVF---LQSEEREK-------------IEEQKRV 3166
+EN+E ++I L K + + ++ RV LQ+E E+ IEE +R
Sbjct: 1574 QKENQELVQEIQEL-KSQINSVSDAKRVLETQLQTESNERSKAVSDHDHLSKQIEELQRA 1632
Query: 3167 LDQALQECEELKNDIQNKHS-------DIDSLR--------------EEQEKLNKQLRCM 3283
L + QE EEL + N D+++L+ E++++L +L +
Sbjct: 1633 LSKVAQEKEELSYNFSNAEEQKKAFMVDVEALKAQLKRQEQENSQLTEDKDQLLSKLEEL 1692
Query: 3284 XXXXXXXXXXXXXXXXXXXXISSNLDSMQLELRNY-----------------NEELKNEI 3412
+ + S+Q + N+ E+L+ ++
Sbjct: 1693 GRQMTSLTTEKDELLASQCKLEQGISSLQTDQENWLAEQSKLLEELKCLQVSQEKLQVDV 1752
Query: 3413 EKKSTDIDLLIKE--------------KEELNERLAYTQKAMEQKEAVLVEKLFEGEQKI 3550
+ TD + L K+ KEE++ +A+ QK+A+ VE+ E Q++
Sbjct: 1753 KVLQTDKETLEKQYQDAVAEVSASTAVKEEISSSIAH---LTAQKDALQVER-NEATQQV 1808
Query: 3551 LLLE-------SSQSATREQTEKYRDLLNSLTEEHADL---KKQFLSATEELQSKERDLE 3700
LE S Q E + K + L LT+E A L K + S +ELQ+ +++LE
Sbjct: 1809 RQLESQLKNAISKQLEAAEASGKTAEALEQLTKEKAVLMQQKNEVQSLLDELQTSKQELE 1868
Query: 3701 VAM----TETKFLKEKLLVSDENL 3760
+ E +E L VS E L
Sbjct: 1869 TQLERLKKENSKYQEDLNVSKEQL 1892
>ref|XP_001582404.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121916639|gb|EAY21418.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 2120
Score = 129 bits (325), Expect = 8e-27
Identities = 251/1286 (19%), Positives = 508/1286 (39%), Gaps = 104/1286 (8%)
Frame = +2
Query: 275 EVEDGGLDTRKSLETKIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTK 454
E+++ ++ K K+ E +E ++ H + L+ N L Q+N + +E+++NT
Sbjct: 791 EIDENKSNSLKQENEKLQEQIEELQKHS-PSPKKLQQENNSLKQENEKLQEEIEELQNTV 849
Query: 455 DLL---DTVESGLYVSNVVSDAV--LNGVVSAQEEEFKEALAAK----------DSENFL 589
D L + ++S ++ + D + L V ++E +E K +EN
Sbjct: 850 DKLQNENNLQSLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENNS 909
Query: 590 LNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKDFIHEKDLMQQ-------- 745
L ++ E L +I L+ T+ + S ++ E + L ++ + K+ ++Q
Sbjct: 910 LKQENEKLQEQIEELQNTIDKLQNSNKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYS 969
Query: 746 --RAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIELQSQNTQSLDCFRRDEIEDQNIK 919
+ Q + L + ++ + E N + L ++ +L N ++ + E+ +K
Sbjct: 970 PNKLQNENESLKQENEKLQEQIEELQNTVEKLQQENDLLKNNKSVSPSPKKLQQENDLLK 1029
Query: 920 EEIEKQIVETIYVTQIQELGEEHDLLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLSH 1099
K + + ++L E++ L+ E+ K Q+EI+ L++ + S ++ K
Sbjct: 1030 NN--KSVSPSP-----KKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSP--KKLQ 1080
Query: 1100 TLEESIMNSNLESLFTAEIYENTFRELGDQISQLR---------NDMY--SKNSYIDSLA 1246
+S++NS + E + +L D+I +L+ ND+ SK+ +
Sbjct: 1081 QENKSMLNSPNKLQNEYETLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKSKSVSPSP 1140
Query: 1247 SRI----DFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKI 1414
R+ + L E KLQE+ L + + + L++E K+
Sbjct: 1141 KRLQQENNSLKQENEKLQEEINQLQNTIEKLQNNKSKLYSPSPKKLQNENESLKQENEKL 1200
Query: 1415 SENLERISKLQKMNNELAERSKSQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEEL 1594
E +E KLQ+ N+ + S S + N + + E+L
Sbjct: 1201 QEQIE---KLQQENDSKPKYSPSPRKLQQE-------------------NNSLKQENEKL 1238
Query: 1595 TDQINIFNSVIDKKEAEVSGH---LDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLV 1765
++I+ + I+K + E + L+T + LQ + E +K Q ++ +S +EKL
Sbjct: 1239 QEEIDQLQNTIEKLQQENNKSKSLLNTPNKLQNEYETLQEENDKLQDEIEELQSTVEKLQ 1298
Query: 1766 --NDSLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQVAVSQE--------QH 1915
N+ L + + + + + E L+ ++ +QN + Q Q
Sbjct: 1299 QENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSPNKLQQ 1358
Query: 1916 IEHQCKEELEGHIADLVLNDFSNDILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDL 2095
+ K+E+E ++ N+ S S+S K L NE +SL Q+
Sbjct: 1359 ENNSLKQEIENLKEEIEQNNKSK---SYSPNK----------------LQNENESLKQEN 1399
Query: 2096 ELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKDGEASD--VQGKSRALRRHSTGQAFR 2269
E K +E ++ L N V + + + L++ K S +Q ++ +L++ + +
Sbjct: 1400 E--KLQEEIEELQNTV----EKLQQENDLLKNNKSVSPSPKKLQNENNSLKQENE----K 1449
Query: 2270 EPPKPEDLYTTYSEGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSF 2449
+ E+L T + + ++ S L+ K L K
Sbjct: 1450 LQEEIEELQNTIDK-------------------LQNSNKSPKKLQQENKSMLNSPNK--- 1487
Query: 2450 AGLKREYELELQRKTEEIYDLKRLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQE 2629
L+ EYE LQ + E++ D + E+ EK+ QE
Sbjct: 1488 --LQNEYET-LQEENEKLQD-------------------------EIEELQSTVEKLQQE 1519
Query: 2630 NKLL-----------PVEEVQRYKMLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSD 2776
N LL P Q L E+LQ +I+ L I++ +N L
Sbjct: 1520 NDLLKNSKSKSVSPSPKRLQQENNSLKQENEKLQEEINQLQNTIEKLQNNKSKLYSPSPK 1579
Query: 2777 ALKKSADHAQRESHLLKHIADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATK 2956
L+ + ++E+ L+ + D + S L + +E E K
Sbjct: 1580 KLQNENESLKQENEKLQEQIEKLQQENDSKPKYSPSPRKLQQENNSLKQENE-------K 1632
Query: 2957 EQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFLQSEE 3136
QE ++Q Q ++ K+ ++ +K L+ NK E L+EE + +
Sbjct: 1633 LQEEIDQLQNTIEKLQQENNKSKSLLNTPNKLQNEY----ETLQEEND----------KL 1678
Query: 3137 REKIEEQKRVLDQALQECEELKND----------IQNKHSDIDSLREEQEKLNKQLRCMX 3286
++KIEE + +++ QE EELKN+ +QN++ +SL++E EKL +++
Sbjct: 1679 QDKIEELQSTIEKLQQENEELKNNKPIYSPSPKKLQNEN---NSLKQENEKLQEEIE--- 1732
Query: 3287 XXXXXXXXXXXXXXXXXXXISSNLDSMQLE------LRNYNEELKNEIEKKSTDIDLLIK 3448
+ + +D +Q+E L+ N LK EIE +I+ K
Sbjct: 1733 ------------------ELQNTIDKLQIENKSPNKLQQENNSLKQEIENLKEEIEQNNK 1774
Query: 3449 EKEELNERLAYTQKAMEQKEAVLVEKL---------FEGEQKILLLESSQSATREQTEKY 3601
K ++L +++Q+ L E++ + E + L+ +++ E+
Sbjct: 1775 SKSYSPKKLQQENNSLKQENEKLQEEIDELQNTVDKLQNENNLQSLQEENDKLQDEIEEL 1834
Query: 3602 RDLLNSLTEEHADLK----------KQFLSATEELQSKERDLEVAMTETKFLKEKLLV-- 3745
+ + L +E+ +LK K+ + L+ + L+ + E + +KL +
Sbjct: 1835 QSTVEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQIEN 1894
Query: 3746 -SDENLKEKDLQLRAFEIANSEKQYQ 3820
S L++++ L+ EI N +++ +
Sbjct: 1895 KSPNKLQQENNSLKQ-EIENLKEEIE 1919
Score = 125 bits (314), Expect = 1e-25
Identities = 259/1231 (21%), Positives = 504/1231 (40%), Gaps = 126/1231 (10%)
Frame = +2
Query: 377 LKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGLYVSNVVSDAVLNGVVSAQEEEFKE 556
L+N N L Q+N + +E+++NT +D +++ N + N + + E KE
Sbjct: 903 LQNENNSLKQENEKLQEQIEELQNT---IDKLQNSNKSPNKLQQE--NNSLKQEIENLKE 957
Query: 557 ALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVILSSHETISERDRLLKD------- 715
+ + K+++ N + E LQ + E + ++ E + + + LLK+
Sbjct: 958 EIEQNNKSKSYSPNKLQNENESLKQENEKLQEQIEELQNTVEKLQQENDLLKNNKSVSPS 1017
Query: 716 ---FIHEKDLMQQRAQ--------ETEQKLASRDNEMMHMVLEK-----DNIILSLHKQI 847
E DL++ + E ++NE + +E+ D + S
Sbjct: 1018 PKKLQQENDLLKNNKSVSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSPK 1077
Query: 848 ELQSQNTQSLDCFRRDEIEDQNIKEEIEK--QIVETIYVTQIQELGEEHDLLRLESAK-- 1015
+LQ +N L+ + + E + ++EE EK +E + T +++L +E+DLL+ +K
Sbjct: 1078 KLQQENKSMLNSPNKLQNEYETLQEENEKLQDEIEELQST-VEKLQQENDLLKNSKSKSV 1136
Query: 1016 ------YQDEIQSLKDECHAKEMSKQAEISKLSHTLEESIMNSNLESLFTA--------- 1150
Q E SLK E Q EI++L +T+E+ + +N L++
Sbjct: 1137 SPSPKRLQQENNSLKQE----NEKLQEEINQLQNTIEK--LQNNKSKLYSPSPKKLQNEN 1190
Query: 1151 EIYENTFRELGDQISQLRNDMYSKNSYIDS---LASRIDFLSSECNKLQEQXXXXXXXXX 1321
E + +L +QI +L+ + SK Y S L + L E KLQE+
Sbjct: 1191 ESLKQENEKLQEQIEKLQQENDSKPKYSPSPRKLQQENNSLKQENEKLQEEIDQLQNTIE 1250
Query: 1322 XXXXXXXTLKASMEMQCSKLKDE---LEEERGKISENLER----ISKLQKMNNELAERSK 1480
K+ + +KL++E L+EE K+ + +E + KLQ+ N EL K
Sbjct: 1251 KLQQENNKSKSLLNTP-NKLQNEYETLQEENDKLQDEIEELQSTVEKLQQENEEL----K 1305
Query: 1481 SQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGH- 1657
+ I N + + E+L ++I + IDK +
Sbjct: 1306 NNKPIYSPSPKKLQNE-----------NNSLKQENEKLQEEIEELQNTIDKLQNSNKSPN 1354
Query: 1658 --LDTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVNDSLHEVDSAFCSLNSRFYSLI 1831
+SL+ + N K EIE++ K +S+ + + N+SL + N + I
Sbjct: 1355 KLQQENNSLKQEIENLKEEIEQNNKS-KSYSPNKLQNENESLKQE-------NEKLQEEI 1406
Query: 1832 HKVDNSGETLRAFVKNIQNQVAVS-------QEQHIEHQCKEELEGHIADL--VLNDFSN 1984
++ N+ E L+ ++N +VS E + Q E+L+ I +L ++ N
Sbjct: 1407 EELQNTVEKLQQENDLLKNNKSVSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQN 1466
Query: 1985 DILSWSRRKEE--AVVHD--------DEFDAERIALLNELKSLHQDLELLKAEEAV--KS 2128
S + ++E ++++ + E L +E++ L +E L+ E + S
Sbjct: 1467 SNKSPKKLQQENKSMLNSPNKLQNEYETLQEENEKLQDEIEELQSTVEKLQQENDLLKNS 1526
Query: 2129 LSNNVGVSTKGIHYFSQLIQEGKDGEASDVQGKSRALRRHSTGQAFREPPKPEDLYTTYS 2308
S +V S K + + +++ + ++ + + ++ P P+ L
Sbjct: 1527 KSKSVSPSPKRLQQENNSLKQENEKLQEEINQLQNTIEKLQNNKSKLYSPSPKKLQNENE 1586
Query: 2309 EGKIVEPHPTEEKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQR 2488
K E+ + L S SP + +Q KQ L+ E + +LQ
Sbjct: 1587 SLKQENEKLQEQIEKLQQENDSKPKYSPSPRK---LQQENNSLKQENEKLQEEID-QLQN 1642
Query: 2489 KTEEIY---DLKRLLLNEKNGL---HAXXXXXXXXXXXXVAEITGKFEKVLQENKLLPVE 2650
E++ + + LLN N L + + E+ EK+ QEN E
Sbjct: 1643 TIEKLQQENNKSKSLLNTPNKLQNEYETLQEENDKLQDKIEELQSTIEKLQQEN-----E 1697
Query: 2651 EVQRYKML-CVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALK---KSADHAQRESH 2818
E++ K + ++LQ++ +SL +E ++ + L + D L+ KS + Q+E++
Sbjct: 1698 ELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTI-DKLQIENKSPNKLQQENN 1756
Query: 2819 LLKH-IADLEAGITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVN--QKQMS 2989
LK I +L+ I S L + +E E + Q TV+ Q + +
Sbjct: 1757 SLKQEIENLKEEIEQNNKSKSYSPKKLQQENNSLKQENEKLQEEIDELQNTVDKLQNENN 1816
Query: 2990 LRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENN-----PGRVFLQSE------E 3136
L+ + E+ DKL +E +E + + L++ EE +NN P LQ+E E
Sbjct: 1817 LQSLQEENDKLQ----DEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQE 1872
Query: 3137 REKIEEQKRVLDQALQECE-------ELKNDIQNKHSDIDSLREEQEKLNKQL----RCM 3283
EK++E+ L + + + +L+ + + +I++L+EE E+ NK + +
Sbjct: 1873 NEKLQEEIEELQNTIDKLQIENKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSPKKL 1932
Query: 3284 XXXXXXXXXXXXXXXXXXXXISSNLDSMQLE-----LRNYNEELKNEIEKKSTDIDLLIK 3448
+ + +D +Q E L+ N++L++EIE+ + ++ L +
Sbjct: 1933 QQENNSLKQENEKLQEEIDELQNTVDKLQNENNLQSLQEENDKLQDEIEELQSTVEKLQQ 1992
Query: 3449 EKEELN----------ERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEK 3598
E EEL ++L +++Q+ L E++ E + I L+ +
Sbjct: 1993 ENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQIENKSP------ 2046
Query: 3599 YRDLLNSLTEEHADLKKQFLSATEELQSKER 3691
N L +E+ LK++ + EE++ +
Sbjct: 2047 -----NKLQQENNSLKQEIENLKEEIEQNNK 2072
Score = 117 bits (292), Expect = 5e-23
Identities = 231/1163 (19%), Positives = 453/1163 (38%), Gaps = 81/1163 (6%)
Frame = +2
Query: 485 YVSNVVSDAVLNGVVSAQEEEFKEALAAKDS---ENFLLNKKIEDLNHKIWSLEETLQYK 655
Y S + + ++ + +E K+ + D+ +N + K+++DL + L+E Y+
Sbjct: 461 YESTITNLRTQINMLKLENQEIKKDIENYDTMEKQNEEMKKQMDDLRSQ---LKENKDYQ 517
Query: 656 EEVILSSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNI---- 823
+ L + + I E + LK+ I + + + E ++KL +NE + + DN+
Sbjct: 518 SQ--LENMKLIQEENDDLKERIGDMSNLSDQILELKKKLNDSENEKEILRKQIDNLCKDD 575
Query: 824 ----ILSLHKQIELQSQNTQSLDCFRRDEIEDQNIKEEIEKQIVETIYVTQIQELGEEHD 991
+ + K I Q L D + E+++KQI E I ++ E+D
Sbjct: 576 EEEDVPTFSKVISDLKVENQILKKKISDSEQISKENEDLKKQINEYI------DIENEND 629
Query: 992 LLRLESAKYQDEIQSLKDECHAKEMSKQAEISKLS--------HTLEESIMN-SNLESLF 1144
L+ E + Q+ IQ + + +E+ KQ + K + H LE+ + N +NL +
Sbjct: 630 ELKDEISTLQNNIQKITE--RNEEIEKQNDDLKKNNDDLHVKIHNLEQKVDNLTNLNNEL 687
Query: 1145 TAEIYENTFRELGDQISQLRNDMYS--------KNSYIDSLASRIDFLSSECNKLQEQXX 1300
T I + + ++ ++ L+N S + + I L R D L +E L +
Sbjct: 688 T--INQMKYEDIKEENDLLKNKSASPVSATPRTQQNKIQQLQMRNDELKTEIEILHQTID 745
Query: 1301 XXXXXXXXXXXXXXTLKASMEMQCSKLKDELEEERGKISENLERISKLQKMNNELAERSK 1480
+++ + LK E E + ++ +I LQ+ +E S
Sbjct: 746 KLTSARIKDND-----SKTVDNEIDLLKKENERLNAMLDDSSMQIIMLQQEIDENKSNSL 800
Query: 1481 SQNSIXXXXXXXXXXXXXXXXXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHL 1660
Q + N + + E+L ++I + +DK + E
Sbjct: 801 KQENEKLQEQIEELQKHSPSPKKLQQENNSLKQENEKLQEEIEELQNTVDKLQNE----- 855
Query: 1661 DTISSLQTVLSNQKFEIEKSQKVLQSFESHIEKLVND---------SLHEVDSAFCSLNS 1813
+ + SLQ + EIE+ Q ++ + E+L N+ L +++ N
Sbjct: 856 NNLQSLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQENE 915
Query: 1814 RFYSLIHKVDNSGETLRAFVK--NIQNQVAVSQEQHIEHQCKEELEGHIADLVLNDFSND 1987
+ I ++ N+ + L+ K N Q S +Q IE+ KEE+E +N
Sbjct: 916 KLQEQIEELQNTIDKLQNSNKSPNKLQQENNSLKQEIEN-LKEEIEQ----------NNK 964
Query: 1988 ILSWSRRKEEAVVHDDEFDAERIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIH 2167
S+S K + ++ E L +++ L +E L+ E + + +V S K +
Sbjct: 965 SKSYSPNKLQN--ENESLKQENEKLQEQIEELQNTVEKLQQENDLLKNNKSVSPSPKKLQ 1022
Query: 2168 YFSQLIQEGKDGEAS--DVQGKSRALRRHSTGQAFREPPKPEDLYTTYSEGKIVEPHPTE 2341
+ L++ K S +Q ++ +L++ + + + E+L T +
Sbjct: 1023 QENDLLKNNKSVSPSPKKLQNENNSLKQENE----KLQEEIEELQNTIDK---------- 1068
Query: 2342 EKKLLAILAFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIYDLKRL 2521
+ ++ S L+ K L K L+ EYE LQ + E++ D
Sbjct: 1069 ---------LQNSNKSPKKLQQENKSMLNSPNK-----LQNEYE-TLQEENEKLQD---- 1109
Query: 2522 LLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKLL-----------PVEEVQRYK 2668
+ E+ EK+ QEN LL P Q
Sbjct: 1110 ---------------------EIEELQSTVEKLQQENDLLKNSKSKSVSPSPKRLQQENN 1148
Query: 2669 MLCVLKEELQSKIDSLLKEIKEKDSNSKVLAEKLSDALKKSADHAQRESHLLKHIADLEA 2848
L E+LQ +I+ L I++ +N L L+ + ++E+ L+ +
Sbjct: 1149 SLKQENEKLQEEINQLQNTIEKLQNNKSKLYSPSPKKLQNENESLKQENEKLQEQIEKLQ 1208
Query: 2849 GITDREIMTSVCSDVLTALFVEMVREKEFSLSLATKEQETVNQKQMSLRKMLEDKDKLLC 3028
D + S L + +E E K QE ++Q Q ++ K+ ++ +K
Sbjct: 1209 QENDSKPKYSPSPRKLQQENNSLKQENE-------KLQEEIDQLQNTIEKLQQENNKSKS 1261
Query: 3029 LVGEENK-----------------EHKRQIAILEKLKEETENNPGRVFLQSEEREKIEEQ 3157
L+ NK E + + +EKL++E E + S +K++ +
Sbjct: 1262 LLNTPNKLQNEYETLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNE 1321
Query: 3158 KRVLDQ----ALQECEELKNDI---QNKHSDIDSLREEQEKLNKQLRCMXXXXXXXXXXX 3316
L Q +E EEL+N I QN + + L++E L +++ +
Sbjct: 1322 NNSLKQENEKLQEEIEELQNTIDKLQNSNKSPNKLQQENNSLKQEIENLKEEIEQNNKSK 1381
Query: 3317 XXXXXXXXXISSNLDSMQLELRNYNEELKNEIEKKSTDIDLLIKEK--EELNERLAYTQK 3490
+ +L +L+ EEL+N +EK + DLL K ++L
Sbjct: 1382 SYSPNKLQNENESLKQENEKLQEEIEELQNTVEKLQQENDLLKNNKSVSPSPKKLQNENN 1441
Query: 3491 AMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDLLNS---LTEEHADLKKQFLS 3661
+++Q+ L E++ E + I L++S + ++ ++ + +LNS L E+ L+++
Sbjct: 1442 SLKQENEKLQEEIEELQNTIDKLQNSNKSPKKLQQENKSMLNSPNKLQNEYETLQEENEK 1501
Query: 3662 ATEELQSKERDLEVAMTETKFLK 3730
+E++ + +E E LK
Sbjct: 1502 LQDEIEELQSTVEKLQQENDLLK 1524
Score = 103 bits (258), Expect = 5e-19
Identities = 245/1258 (19%), Positives = 500/1258 (39%), Gaps = 107/1258 (8%)
Frame = +2
Query: 320 KIAETLERMEIHEGDTANTLKNMNFDLGQDNPGVPGLLEDIRNTKDLLDTVESGLYVSNV 499
K E + ME + + ++ L ++N LE+++ ++ D ++ + +
Sbjct: 484 KDIENYDTMEKQNEEMKKQMDDLRSQL-KENKDYQSQLENMKLIQEENDDLKERIGDMSN 542
Query: 500 VSDAVLNGVVSAQEEEFKEALAAKDSENFLLNKKIEDLNHKIWSLEETLQYKEEVI---L 670
+SD +L + E ++ + K +N + + ED+ + L+ + +++ +
Sbjct: 543 LSDQILELKKKLNDSENEKEILRKQIDNLCKDDEEEDVP-TFSKVISDLKVENQILKKKI 601
Query: 671 SSHETISERDRLLKDFIHEKDLMQQRAQETEQKLASRDNEMMHMVLEKDNIILSLHKQIE 850
S E IS+ + LK I+E ++ E + ++++ N + + + I KQ +
Sbjct: 602 SDSEQISKENEDLKKQINEYIDIENENDELKDEISTLQNNIQKITERNEEI----EKQND 657
Query: 851 LQSQNTQSLDCFRRDEIEDQNIKEEIEKQI----VETIYVTQIQELGEEHDLLRLESAKY 1018
+N L ++ N++++++ TI + +++ EE+DLL+ +SA
Sbjct: 658 DLKKNNDDL------HVKIHNLEQKVDNLTNLNNELTINQMKYEDIKEENDLLKNKSAS- 710
Query: 1019 QDEIQSLKDECHAKEMSKQAEISKLSHTLEE-----SIMNSNLESLFTAEIYENTFRELG 1183
A ++Q +I +L +E I++ ++ L +A I +N + +
Sbjct: 711 ---------PVSATPRTQQNKIQQLQMRNDELKTEIEILHQTIDKLTSARIKDNDSKTVD 761
Query: 1184 DQISQLRNDMYSKNSYIDSLASRIDFLSSECNKLQEQXXXXXXXXXXXXXXXXTLKASME 1363
++I L+ + N+ +D + +I L E ++ + S++
Sbjct: 762 NEIDLLKKENERLNAMLDDSSMQIIMLQQEIDENKSN--------------------SLK 801
Query: 1364 MQCSKLKDELEEERGKISENLERISKLQKMNNELA-ERSKSQNSIXXXXXXXXXXXXXXX 1540
+ KL++++EE + ++ KLQ+ NN L E K Q I
Sbjct: 802 QENEKLQEQIEE----LQKHSPSPKKLQQENNSLKQENEKLQEEIEELQNTVDKLQNENN 857
Query: 1541 XXXXXVVNMAFGSKLEELTDQINIFNSVIDKKEAEVSGHLDTISSLQTVLSNQKFEIEKS 1720
N ++EEL + ++ + + + LQ ++ K E EK
Sbjct: 858 LQSLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQENEKL 917
Query: 1721 QKVLQSFESHIEKLVND--SLHEVDSAFCSLNSRFYSLIHKVDNSGETLRAFVKNIQNQ- 1891
Q+ ++ ++ I+KL N S +++ SL +L +++ + ++ +QN+
Sbjct: 918 QEQIEELQNTIDKLQNSNKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSPNKLQNEN 977
Query: 1892 VAVSQEQHIEHQCKEELEGHIADLVL-NDF--SNDILSWSRRK----EEAVVHDDEFDAE 2050
++ QE + EEL+ + L ND +N +S S +K + + ++
Sbjct: 978 ESLKQENEKLQEQIEELQNTVEKLQQENDLLKNNKSVSPSPKKLQQENDLLKNNKSVSPS 1037
Query: 2051 RIALLNELKSLHQDLELLKAEEAVKSLSNNVGVSTKGIHYFSQLIQEGKD--GEASDVQG 2224
L NE SL Q+ E K +E ++ L N + +L QE K + +Q
Sbjct: 1038 PKKLQNENNSLKQENE--KLQEEIEELQNTIDKLQNSNKSPKKLQQENKSMLNSPNKLQN 1095
Query: 2225 KSRALRRHSTG--------QAFREPPKPEDLYTTYSEGKIVEPHPT-----------EEK 2347
+ L+ + Q+ E + E+ S+ K V P P E +
Sbjct: 1096 EYETLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKSKSVSPSPKRLQQENNSLKQENE 1155
Query: 2348 KLLAIL-----AFETADASDSPLRNWPKEQLLGHFKQSFAGLKREYELELQRKTEEIY-- 2506
KL + E + S L + P + L + +S LK+E E +LQ + E++
Sbjct: 1156 KLQEEINQLQNTIEKLQNNKSKLYS-PSPKKLQNENES---LKQENE-KLQEQIEKLQQE 1210
Query: 2507 -DLK-------RLLLNEKNGLHAXXXXXXXXXXXXVAEITGKFEKVLQENKL------LP 2644
D K R L E N L + ++ EK+ QEN P
Sbjct: 1211 NDSKPKYSPSPRKLQQENNSLKQENEKLQEE----IDQLQNTIEKLQQENNKSKSLLNTP 1266
Query: 2645 VEEVQRYKMLCVLK-------EELQSKIDSLLKEIKEKDSNSKVLA------EKLSDALK 2785
+ Y+ L EELQS ++ L +E +E +N + + + +++LK
Sbjct: 1267 NKLQNEYETLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENNSLK 1326
Query: 2786 KSADHAQRESHLLKHIADLEAGITD-----REIMTSVCSDV--LTALFVEMVREKEFSLS 2944
+ + Q E L++ D ++ S+ ++ L + + K +S +
Sbjct: 1327 QENEKLQEEIEELQNTIDKLQNSNKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSPN 1386
Query: 2945 LATKEQETVNQKQMSLRKMLEDKDKLLCLVGEENKEHKRQIAILEKLKEETENNPGRVFL 3124
E E++ Q+ L++ +E+ + + +EN K ++ K+ N
Sbjct: 1387 KLQNENESLKQENEKLQEEIEELQNTVEKLQQENDLLKNNKSVSPSPKKLQNENNSLKQE 1446
Query: 3125 QSEEREKIEEQKRVLD----------QALQECEELKNDIQNKHSDIDSLREEQEKLNKQL 3274
+ +E+IEE + +D + QE + + N ++ ++L+EE EKL ++
Sbjct: 1447 NEKLQEEIEELQNTIDKLQNSNKSPKKLQQENKSMLNSPNKLQNEYETLQEENEKLQDEI 1506
Query: 3275 -RCMXXXXXXXXXXXXXXXXXXXXISSNLDSMQLE---LRNYNEELKNEIEKKSTDIDLL 3442
+S + +Q E L+ NE+L+ EI + I+ L
Sbjct: 1507 EELQSTVEKLQQENDLLKNSKSKSVSPSPKRLQQENNSLKQENEKLQEEINQLQNTIEKL 1566
Query: 3443 IKEKEEL----NERLAYTQKAMEQKEAVLVEKLFEGEQKILLLESSQSATREQTEKYRDL 3610
K +L ++L ++++Q+ EKL E +K+ S+ K +
Sbjct: 1567 QNNKSKLYSPSPKKLQNENESLKQEN----EKLQEQIEKLQQENDSKPKYSPSPRKLQQE 1622
Query: 3611 LNSLTEEHADLKK---QFLSATEELQSK-ERDLEVAMTETKFLKEKLLVSDENLKEKD 3772
NSL +E+ L++ Q + E+LQ + + + T K E + +EN K +D
Sbjct: 1623 NNSLKQENEKLQEEIDQLQNTIEKLQQENNKSKSLLNTPNKLQNEYETLQEENDKLQD 1680