BLASTX nr result
ID: Ephedra28_contig00002617
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Ephedra28_contig00002617
(2303 letters)
Database: ./nr
37,332,560 sequences; 13,225,080,153 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|XP_001318162.1| viral A-type inclusion protein [Trichomonas ... 134 2e-28
ref|XP_005159743.1| PREDICTED: titin isoform X6 [Danio rerio] 126 4e-26
ref|XP_005159742.1| PREDICTED: titin isoform X5 [Danio rerio] 126 4e-26
ref|XP_005159741.1| PREDICTED: titin isoform X4 [Danio rerio] 126 4e-26
ref|XP_005159738.1| PREDICTED: titin isoform X1 [Danio rerio] 126 4e-26
ref|XP_685984.6| PREDICTED: titin isoform X7 [Danio rerio] 126 4e-26
ref|XP_003701630.1| PREDICTED: major antigen-like [Megachile rot... 126 5e-26
ref|XP_006560777.1| PREDICTED: sporulation-specific protein 15 i... 125 1e-25
gb|EGI67148.1| Cytochrome P450 6B3 [Acromyrmex echinatior] 125 1e-25
ref|XP_006560776.1| PREDICTED: sporulation-specific protein 15 i... 125 1e-25
ref|XP_001582404.1| viral A-type inclusion protein [Trichomonas ... 124 2e-25
ref|XP_001330650.1| viral A-type inclusion protein [Trichomonas ... 120 3e-24
ref|XP_653447.1| Viral A-type inclusion protein repeat [Entamoeb... 119 6e-24
ref|XP_001319569.1| viral A-type inclusion protein [Trichomonas ... 118 1e-23
ref|XP_807004.1| hypothetical protein [Trypanosoma cruzi strain ... 117 2e-23
ref|XP_006612821.1| PREDICTED: sporulation-specific protein 15-l... 117 3e-23
ref|XP_001739846.1| intracellular protein transport protein USO1... 117 3e-23
ref|XP_001323236.1| viral A-type inclusion protein [Trichomonas ... 114 2e-22
ref|XP_001581403.1| viral A-type inclusion protein [Trichomonas ... 113 4e-22
gb|EAR95694.2| hypothetical protein TTHERM_00268040 [Tetrahymena... 112 5e-22
>ref|XP_001318162.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121900914|gb|EAY05939.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 5296
Score = 134 bits (337), Expect = 2e-28
Identities = 131/619 (21%), Positives = 299/619 (48%), Gaps = 53/619 (8%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
++ + L E K E ++ N +Q ++ + N+NL E K+N L ++ ++N+
Sbjct: 2780 EKATNLENENKSLKEENEDLMNQNKQLEKEKQQLLAQNSNLEENKNNQEQSLMNRKKKND 2839
Query: 2123 E---QRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK 1953
+ Q L+ +++ +++ ++ ++T+ + N+Q+ +++D +N+ KE + A D
Sbjct: 2840 DLLKQIDDLKLELEELKRNNSQNETKLQNANQQIEMMKDQINNDKEQIKSAQD------- 2892
Query: 1952 QLQDLENQK-ETVSKELALSVSRE--QKLASDLKALSEK--EESTK--NQLLIQTEQNKQ 1794
+L DL+N+ E S ++ L ++ + L +D+K+ ++K +E+ K +Q++ T+QN +
Sbjct: 2893 KLNDLQNKNNELNSNQIVLENQKKMYEGLYNDMKSSNDKLNDENRKKTDQIIDLTKQNAE 2952
Query: 1793 ---LELEIEKLYGSL------------------QMKQMENTLLKDGNEKIYDLCKLLATK 1677
L+LE ++L L Q+++++ L NEK K + T+
Sbjct: 2953 VSALKLENQRLNSELEKLKSNQPVSSNDPELQKQIEELKKQLNNLSNEK-----KQIETE 3007
Query: 1676 SREVQGQ-------QEGIL--KQDINIE--------DELAR-TKEVGRSATDMKKVNSDA 1551
+QGQ E ++ K+D+ + DE+ R + ++ T +++ N+
Sbjct: 3008 KNGLQGQIGRLESQNESLIESKKDMKEQNDKLQAQMDEMRRENNSLRQNQTQLERTNNGL 3067
Query: 1550 GAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIR 1371
KV + + L +K+ + +L+++ + S N+ + ++ E++ + K+ + +++ +
Sbjct: 3068 ENKVGNLTDQLNQVKNQLSALQDQ----LKSKENENEKLRNEREKLANEKNSVELQSKDK 3123
Query: 1370 AQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQN 1191
E+++L+++ + + + L + LQ + + ++ K ++NN+ ++N N+E +
Sbjct: 3124 DAEIIKLKSDAEHLNDKINSLNDEKNKLQQANDKLNDQIEQMKQQINNLTNENKNMEQEK 3183
Query: 1190 RSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILL 1011
+ ++ K Q++EE++ +E E++ +E++ LK +KE D ++L
Sbjct: 3184 AKNQEKIQNIEPKLKQLEEEKSKLEDENSQNENEIQRLKDTIKELSDKLAKSEEDNKLLK 3243
Query: 1010 GQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAE 831
+E +E L ++ D+L L +EN +LK + N ++AE
Sbjct: 3244 QSSSGTTDKQVED---LQEMLNKLRDDLKNLNSENEQLKQQKDQLSEKLNNSNNDKTKAE 3300
Query: 830 AMSVLISKSLG--NGRANQ--REFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFET 663
+ +SK L N NQ +++N +D + V++ K + +KL+ + E +
Sbjct: 3301 TQNEQLSKQLEQLNNEKNQMFNKYKNAIQDKAKVEIAKETLAK---DNEKLASEKESLQQ 3357
Query: 662 KSREAQQMANKLEEMQQTL 606
K A NKLE+ + L
Sbjct: 3358 KLDSANDEKNKLEQDKHKL 3376
Score = 105 bits (261), Expect = 1e-19
Identities = 144/765 (18%), Positives = 312/765 (40%), Gaps = 38/765 (4%)
Frame = -1
Query: 2279 EEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQN 2100
E+ +H +E+ K D +E + L Q+ N +L++KLQ+ EE+++ L+
Sbjct: 3370 EQDKHKLEIDNT------KLNDAKSHLENEKSQLAQQIN---DLNNKLQKLEEEKNKLEE 3420
Query: 2099 DMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKET 1920
+ E+ SQ + ++L +Q L + +K+ L +++ +E+Q +++N+
Sbjct: 3421 EKAQNEKKLENSQQDGDKLGQQNQDLLKQLEEIKQKLQQTEQEKSALEQQKNEIQNKLNE 3480
Query: 1919 VSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQME 1740
+ +++ S ++ + L+ + +++ T+ +L +Q +++ ++E+ + + E
Sbjct: 3481 IEQQMKDSEKEKEDIKQKLQQVEQEKSETQKKLEEAEQQKNEIQNKLEQTEQEKKNLENE 3540
Query: 1739 NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVN 1560
+ ++ + K LA + E + + E + + E +L +E ++ + K
Sbjct: 3541 KAETEKRLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEANKNLENEKNET 3600
Query: 1559 -------SDAGAKVSGILEMLLPMKDDVFSLKEEVLGNI-------NSLRNDAQMVQVAL 1422
A+ +LE K ++ + K E + +L N+ + L
Sbjct: 3601 QKKLEEAEQQKAETQKLLEQTEEAKKNLANEKSEAERKLQETEEAKKNLANEKSEAERKL 3660
Query: 1421 EQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIEL---KRKNQTLQDESQRNAKELW 1251
E++Q+ K+E + + L+ E + Q L E K + Q L ++++ K L
Sbjct: 3661 EEVQNEKAETERKLNEAEEANKNLENEKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLA 3720
Query: 1250 NAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKS 1071
N K+ + + E ++L E +K ++Q E+ E + N +NL++
Sbjct: 3721 NEKSEAERKLQET---EEAKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEANKNLEN 3777
Query: 1070 ELKES-KDLEGYFLRLFEI-LLGQHVEVASLDIESCRFAEEKLMRILDELICLRN-ENAK 900
E E+ K LE + E L + E A ++E+ + EK ++ +E +N E K
Sbjct: 3778 EKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLENEKSETEKKLQETEE--AKKNLEQEK 3835
Query: 899 LKNEALYEYHDYERKNVSGSRAEAMSVL-----ISKSLGNGRA-NQREFQNKEEDSSGVD 738
+ + ++ N+ +AE +L K+L N +A ++ Q EE +
Sbjct: 3836 SDIQKKLDETKQQKVNLENEKAETQKLLEETEEAKKNLENEKAETEKRLQETEEAKKNLA 3895
Query: 737 LLKNKCTRLEFQVQ--------KLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXX 582
K++ R +VQ KL+E E + E + KLEE +Q ++
Sbjct: 3896 NEKSEAERKLEEVQNEKAETERKLNEAEEANKNLENEKNETQKKLEEAEQQKAETQKLLE 3955
Query: 581 XXXXXXIRVRSLKKENTRL---RSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQX 411
+ + K E + E K L +S ++ K+ + E++ Q
Sbjct: 3956 QTEEAKKNLENEKSETEKKLQETEEAKKNLEQEKSDIQKKLDETKQQKVNLENEKAETQK 4015
Query: 410 XXXXXXXXXXKIDTRTSETQ-EIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXX 234
++ +ETQ ++D + + S K+ + +QN L+
Sbjct: 4016 LLEETEEAKKNLENEKAETQKKLDEAEEAKKNLEQEKSDAEKKLEEVQNEKSALEN---- 4071
Query: 233 XXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDV 99
+ N +K+L+E Q+VE + +++ +
Sbjct: 4072 ---------------EKNETQKKLEEAEKAKDQIVEEKSAVERQL 4101
Score = 96.7 bits (239), Expect = 4e-17
Identities = 125/609 (20%), Positives = 265/609 (43%), Gaps = 8/609 (1%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIE---LQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQ 2133
K+++ L E+KQ E LQ L +NE + IE+ ++ EQ D + ++ +
Sbjct: 2992 KQLNNLSNEKKQIETEKNGLQGQIGRLESQNESL---IESKKDMKEQNDKLQAQMDEMRR 3048
Query: 2132 ENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK 1953
EN R QN Q +E+ + + + L QL +++ ++ L++ L ++ +
Sbjct: 3049 ENNSLR---QNQTQ-LERTNNGLENKVGNLTDQLNQVKNQLSALQDQLKSKENENEKLRN 3104
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEK 1773
+ + L N+K +V + + KL SD + L++K S ++ + N +L +IE+
Sbjct: 3105 EREKLANEKNSVELQSKDKDAEIIKLKSDAEHLNDKINSLNDEKNKLQQANDKLNDQIEQ 3164
Query: 1772 LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEV 1593
+ + EN ++ K + + + K ++++ ++ + ++ E+E+ R K+
Sbjct: 3165 MKQQINNLTNENKNMEQEKAKNQEKIQNIEPKLKQLEEEKSKLEDENSQNENEIQRLKDT 3224
Query: 1592 GRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLK--EEVLGNINSLRNDAQMVQVALE 1419
+ +D K S+ K LL + K E++ +N LR+D + + E
Sbjct: 3225 IKELSD-KLAKSEEDNK-------LLKQSSSGTTDKQVEDLQEMLNKLRDDLKNLNSENE 3276
Query: 1418 QMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKA 1239
Q++ K +L + + + + + + +L ++ + L +E + + NA
Sbjct: 3277 QLKQQKDQLSEKLNNSNNDKTKAETQNE-------QLSKQLEQLNNEKNQMFNKYKNAIQ 3329
Query: 1238 RLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKE 1059
V L N L +E QK +E+N +E + + L E++N K L +
Sbjct: 3330 DKAKVEIAKETLAKDNEKLASEKESLQQKLDSANDEKNKLEQDKHKL--EIDNTK--LND 3385
Query: 1058 SKD-LEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKL--KNE 888
+K LE +L + + + ++ L+ E + EEK +L + + KL +N+
Sbjct: 3386 AKSHLENEKSQLAQQINDLNNKLQKLEEEKNKLEEEKAQN-EKKLENSQQDGDKLGQQNQ 3444
Query: 887 ALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLE 708
L + + ++ + + E ++ K+ + N+ E Q K+ + D +K K ++E
Sbjct: 3445 DLLKQLEEIKQKLQQTEQEKSALEQQKNEIQNKLNEIEQQMKDSEKEKED-IKQKLQQVE 3503
Query: 707 FQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTR 528
Q+ SE + E ++ ++ NKLE+ +Q ++ KK
Sbjct: 3504 ---QEKSETQKKLEEAEQQKNEIQNKLEQTEQEKKNLENEKAETEKRLQETEEAKKNLAN 3560
Query: 527 LRSEMKGEL 501
+SE + +L
Sbjct: 3561 EKSEAERKL 3569
Score = 91.7 bits (226), Expect = 1e-15
Identities = 140/779 (17%), Positives = 310/779 (39%), Gaps = 19/779 (2%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
K ++ E+ KQ +L E N + E + LEQ +N ++ +K +
Sbjct: 3269 KNLNSENEQLKQQKDQLSEKLNNSNNDKTKAETQNEQLSKQLEQLNNEKNQMFNKYKNAI 3328
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQ 1944
+ ++ ++ +++ + + +E+E L ++L D+ N L++ D +
Sbjct: 3329 QDKAKVEIAKETLAKDNEKLASEKESLQQKLDSANDEKNKLEQDKHKLEIDNTKLNDAKS 3388
Query: 1943 DLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQT---------EQNKQL 1791
LEN+K +++++ ++ QKL + L +EE +N+ ++ +QN+ L
Sbjct: 3389 HLENEKSQLAQQINDLNNKLQKLEEEKNKL--EEEKAQNEKKLENSQQDGDKLGQQNQDL 3446
Query: 1790 ELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDEL 1611
++E++ LQ + E + L+ +I + K E++ Q + K+ +I+ +L
Sbjct: 3447 LKQLEEIKQKLQQTEQEKSALEQQKNEIQN-------KLNEIEQQMKDSEKEKEDIKQKL 3499
Query: 1610 ARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQ 1431
+ E +S T K LE K+++ + E+ +L N+ +
Sbjct: 3500 QQV-EQEKSETQKK-------------LEEAEQQKNEIQNKLEQTEQEKKNLENEKAETE 3545
Query: 1430 VALEQMQDTKSELF---AEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAK 1260
L++ ++ K L +EAE + +EV +AE + + E + + ++E+Q+ +
Sbjct: 3546 KRLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEANKNLENEKNETQKKLE 3605
Query: 1259 ELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVEN 1080
E KA ++ + + + K+E + Q+ + ++ +SE EV+N
Sbjct: 3606 EAEQQKAETQKLLEQTEEAKKNLANEKSEAERKLQETEEAKKNLANEKSEAERKLEEVQN 3665
Query: 1079 LKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAK 900
K+E + + E A+ ++E+ + +K + E K
Sbjct: 3666 EKAETERKLN---------------EAEEANKNLENEKNETQKKLE--------EAEQQK 3702
Query: 899 LKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKC 720
+ + L E + +KN++ ++EA L A + K E ++ ++N+
Sbjct: 3703 AETQKLLEQTEEAKKNLANEKSEAERKLQETE----EAKKNLANEKSEAERKLEEVQNEK 3758
Query: 719 TRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKK 540
E +KL+E E + E + KLEE +Q ++ + + K
Sbjct: 3759 AETE---RKLNEAEEANKNLENEKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLENEKS 3815
Query: 539 ENTRL---RSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDT 369
E + E K L +S ++ K+ + E++ Q ++
Sbjct: 3816 ETEKKLQETEEAKKNLEQEKSDIQKKLDETKQQKVNLENEKAETQKLLEETEEAKKNLEN 3875
Query: 368 RTSETQE-IDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGG 192
+ET++ + + + N S ++ + +QN E ++
Sbjct: 3876 EKAETEKRLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEANKNLEN---- 3931
Query: 191 IDMNSIEKQLKEL---NIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEE 24
+ N +K+L+E +L+E KK+++ ++ + E+KL+ EE
Sbjct: 3932 -EKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLE---------NEKSETEKKLQETEE 3980
Score = 81.6 bits (200), Expect = 1e-12
Identities = 110/609 (18%), Positives = 252/609 (41%), Gaps = 42/609 (6%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEE 2121
++ + +E KQ + L EN A QK +E + +N E KL E EE
Sbjct: 3991 DIQKKLDETKQQKVNL-ENEKAETQK------LLEETEEAKKNLENEKAETQKKLDEAEE 4043
Query: 2120 QRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQD 1941
+ L+ + E+ Q E+ L + + + ++A V++++ +E+QL +
Sbjct: 4044 AKKNLEQEKSDAEKKLEEVQNEKSALENEKNETQKKLEEAEKAKDQIVEEKSAVERQLVE 4103
Query: 1940 LENQKETVSKELALSVSREQKLASDL--------KALSEKEESTKNQLLIQTEQNKQLEL 1785
+ K+ S+ Q+ SDL K L++KE + + + + KQL+
Sbjct: 4104 SQKDSSENQKQQDEEKSKLQQQLSDLQNKLNDLEKKLADKENEKEQEKTQKDDLQKQLD- 4162
Query: 1784 EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 1605
+++K + +L+ ++ + D ++ D +L ++ + ++DE +
Sbjct: 4163 QLQKDFDNLEREKQKLQDKNDSMKETIDSKNMLLDSFGTIKDHLNDANNNNKKLQDENNK 4222
Query: 1604 TKEVGRSAT----DMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQM 1437
++ + AT +++ + D K++ + D EE L N A+
Sbjct: 4223 LRDDAQKATSKNNELQSIIDDLNRKLANL--------DAEKKATEEKLKNTEDKLKQAEA 4274
Query: 1436 VQVA----LEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQR 1269
+ A L + ++ K E + +E +++ ++ A + E + K + +DE +
Sbjct: 4275 EKKATEDKLRETENAKKETEEKLAKTEEEKKQVEDKLAATEAAKKETEDKLKQTEDEKKA 4334
Query: 1268 NAKELWNAKA--------------RLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEE 1131
+L N +A +L + +E++ ++ + +LH + + +++
Sbjct: 4335 TEDKLANVEAEKSDIEQAKKETEDKLKQTEEEKAAVEAEKKATEDKLHETEEAKKETEDK 4394
Query: 1130 RNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEK 951
E E + + + +LK++++ + E + E+ ES R + EK
Sbjct: 4395 LKQTEDEKAAVEQAKKETEDKLKQTEEEKKATENKLEESEAEKKELGE-RFESSRGSTEK 4453
Query: 950 --------LMRILDELICLRNENAKLKNEALYEYHDYERK----NVSGSRAEAMSVLISK 807
L ++ DEL ++ + ++L E+ + + E+K ++ + E ++ +K
Sbjct: 4454 QVSDLENLLSKLKDELKNIKEDKSQL--ESKLKQAEAEKKATEDKLAKTEVEKAALEQAK 4511
Query: 806 SLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKL 627
+ E + K ++ DL K K T L+ + KL ++ E + + + ++ AN L
Sbjct: 4512 KETEDKLANVENEKKATETQKNDLAKEK-TDLQKALAKLLKRQEQLDAEKKALEEKANAL 4570
Query: 626 EEMQQTLSD 600
E ++ +
Sbjct: 4571 ESEKKATEE 4579
Score = 81.3 bits (199), Expect = 2e-12
Identities = 115/571 (20%), Positives = 243/571 (42%), Gaps = 36/571 (6%)
Frame = -1
Query: 2279 EEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQK----DNIIVELSHKLQENEEQRS 2112
E+K +L+E NA ++ E + K E +E K + E KL++ E+++
Sbjct: 4275 EKKATEDKLRETENAKKETEEKLA-KTEEEKKQVEDKLAATEAAKKETEDKLKQTEDEKK 4333
Query: 2111 ALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAF-MEKQLQDLE 1935
A ++ + +VE + + ++E +L ++ + EA A +D+ E+ ++ E
Sbjct: 4334 ATEDKLANVEAEKSDIEQAKKETEDKLKQTEEEKAAV-EAEKKATEDKLHETEEAKKETE 4392
Query: 1934 NQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSL- 1758
++ + E A +++ LK E++++T+N+L + K+L E GS
Sbjct: 4393 DKLKQTEDEKAAVEQAKKETEDKLKQTEEEKKATENKLEESEAEKKELGERFESSRGSTE 4452
Query: 1757 -QMKQMENTL--LKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGR 1587
Q+ +EN L LKD + I + L +K ++ + +++ ED+LA+T+
Sbjct: 4453 KQVSDLENLLSKLKDELKNIKEDKSQLESKLKQAEAEKKAT-------EDKLAKTEVEKA 4505
Query: 1586 SATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQV------- 1428
+ KK D A V + K+D+ K ++ + L + +
Sbjct: 4506 ALEQAKKETEDKLANVENEKKATETQKNDLAKEKTDLQKALAKLLKRQEQLDAEKKALEE 4565
Query: 1427 ---ALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKE 1257
ALE + E A AE +E Q ++ + L + + + + +D+ ++ E
Sbjct: 4566 KANALESEKKATEEKLANAEKEKKET---QDKLKQTEDNLAKSESEKKATEDKLKQTESE 4622
Query: 1256 LWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENL 1077
+A K N E++ ++ + +L ++ +E+ E+E ++ N+
Sbjct: 4623 KAQIEAAKKETEDKLQNAENEKKAAEEKLKQSEEQKKATEEKLQEAEAEKKAEQEKLANI 4682
Query: 1076 KSEL--------KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELIC 921
++E K+ DL G +L ++L ++A E+ + A+E+L + +
Sbjct: 4683 EAEKQQLGNASEKQVSDLSGEISKLKQLL----KQLA----EAKKKADEELAKSKQDKEQ 4734
Query: 920 LRNENAKLK---NEALYEYHDYER-KNVSGSRAEAMSVLISKSLGNGRANQREFQNKEED 753
N+ +KL+ N + D E+ K S S + ++ ++K + E +N +
Sbjct: 4735 SDNDKSKLQEDLNNLKKQLEDLEKAKKESDSNNKLLADSVNKLKEQNKQKDDEIKNLTDK 4794
Query: 752 SSGVDLLKN-----KCTRLEFQVQKLSEKAE 675
++ + N K + Q+ K +EK E
Sbjct: 4795 ANQPQDINNNPDFVKVKKAFLQLSKTNEKLE 4825
Score = 77.4 bits (189), Expect = 3e-11
Identities = 147/782 (18%), Positives = 295/782 (37%), Gaps = 111/782 (14%)
Frame = -1
Query: 2276 EKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQND 2097
E+ T + Q A+ Q + K+ + N L++ + E+ + + +E +
Sbjct: 205 ERYTTYDAQ--LRAISQAALRLSTKVNSLNAELQELKHSQSEMQIIVSQYKEVVPKISFH 262
Query: 2096 MQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETV 1917
++++E++ +++ T+ ++ N + R + ++ + D+ K+LQ L+ Q E
Sbjct: 263 IETIEKLVSINDTDEDDKNPLIFPQR--LKRIRSEVQRLFDNNEKTNKELQKLKEQLELY 320
Query: 1916 SK-ELALSVSREQKLASDLKALSEKEESTKNQLLI--QTEQNKQLELEIEKLYGSLQMKQ 1746
+ S+ Q L+ EK+ + QL Q++Q+ QL EIE++ +Q
Sbjct: 321 ENMKNGQSMKERQAELESLRLELEKKNAELEQLKARYQSKQDPQLLAEIERIENEVQ--N 378
Query: 1745 MENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKK 1566
++N + D +I L L+A + + ++E I N+E E+ K++ + D K
Sbjct: 379 LKNKIA-DRESQIKALNLLIAQYQTDDEDKKEIIE----NLEKEI---KDLKKQIEDKDK 430
Query: 1565 VNSDAGAKVSGILEMLLPMKDD---VFSLKEEVLGNIN-------SLRNDAQMVQVALE- 1419
AK++ I E+ +D+ V ++ LG+ N SL + + ++ L+
Sbjct: 431 EIEVLKAKIAKIEEIPEDEEDEDIVVAGTRDVDLGDFNEEEAEQVSLEDQVKQLKEKLDD 490
Query: 1418 ------QMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQ--------- 1284
QM+ + AE E +++ L+ D + + EL KN LQ
Sbjct: 491 KKKNGVQMKQALASKDAEIEKLNEQIQELKDRNDKQEQNIEELNTKNSDLQNSNDEYKKL 550
Query: 1283 -DESQRNAKELWNAKAR---LNN-----------------------VMSKNINLESQNRS 1185
DE Q K+L KA LNN + ++ L+S+N
Sbjct: 551 IDELQNQLKDLAKNKAESSDLNNSENTKQDSEKAEDENAETKSNKELQEESDKLKSENEG 610
Query: 1184 LKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQ 1005
LK L + + + E++ L SE+ LKSE+ E + R EIL +
Sbjct: 611 LKKSLENLKKSNDDLNKSNEDKENKIKELESEISKLKSEINELEQNNKDKDREIEILSSK 670
Query: 1004 HVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAM 825
+ +++++ +E + ++ +E NE + N + + E
Sbjct: 671 VSSIENVNLDD----DEDDITVVGTRDISVDETIPTDNETETKTEPETNTNTNENTNETN 726
Query: 824 SVLISKSLGNGRANQREFQNKEE---------------DSSGVDLLKNKCTRLEFQVQKL 690
+S GN N+ + Q+KE+ VD LK++ L+ + + L
Sbjct: 727 EENVSSQEGN---NEEKNQSKEDKKKLRIQQLKQLLASKQGEVDALKSQNDDLKSENETL 783
Query: 689 SEKAEMFETKSREAQQMANKLEE------------------------------------- 621
S+ ETK++E ++ +
Sbjct: 784 SKSNHELETKNKELEEEIENINNNKEGEVIDEKEASDVEVVCSTRDVDFEYENENDPETL 843
Query: 620 ---MQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEI 450
++ LS++ ++ LK EN L+ E++ + S K
Sbjct: 844 KSLLKSKLSELENLQKENTDLMKQIEELKNENENLKRELENLKLENESLKRENERLQLTA 903
Query: 449 NIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQ 270
+ + +I+ + +T EI+ L +N++ K+ + L+
Sbjct: 904 DQSPQSKDKMIELLANQINQLESLVPELQQKTNEIEELKKENKQIKEENEKLKKENEDLK 963
Query: 269 NS 264
S
Sbjct: 964 KS 965
Score = 75.9 bits (185), Expect = 7e-11
Identities = 149/792 (18%), Positives = 326/792 (41%), Gaps = 52/792 (6%)
Frame = -1
Query: 2240 NALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVE-QMHAVS 2064
N L +K+++I +E L Q + I + ++N++ LQ + + ++
Sbjct: 2467 NVLEKKSDEINKALE--EILHRQNEEIKALRDREAEKNKQTVDDLQKQIAMLNNKLKPSD 2524
Query: 2063 QTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSRE 1884
QT+ ++L ++L+ +E + +DR ++ L+ +E++ + +L S++ +
Sbjct: 2525 QTDNDQLQKELMF--------QEIEGESPEDRN--KRYLKAIEDKFNEIIAKLQESINNQ 2574
Query: 1883 QKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIY 1704
+ +LK L +K + + + +Q Q K EI+ Y + ++ + +++ N+K+
Sbjct: 2575 NE---ELKKLRQKCDGV-DAIELQLAQKKAELNEIKDNYEKEKAEREKE--VEENNKKLK 2628
Query: 1703 DLCKLLATKSREVQGQQEGILKQDINIEDELAR-TKEVGRSATDMKKVNSDAGAKVSGIL 1527
D L + + QG+Q + IN ++ AR KE SA +K A+++ +
Sbjct: 2629 DTINALENRL-DSQGEQT---RSKINSAEQTARKAKEDADSAVIAQK---SLQAELNNLK 2681
Query: 1526 EMLLPMKDDVFSLKE---EVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVL 1356
+ ++D + + KE + + L + V + + + +L + E
Sbjct: 2682 QKYAVLEDQLKTEKENHQQEAQQLKELAEEDATPMVCIHVVGEKLKKLQNDNE------- 2734
Query: 1355 RLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKA 1176
+L D +Q + ELK K L+ + +++A EL N +L + K NLE++N+SLK
Sbjct: 2735 KLSENNDNLQKNINELKDKINGLEKQYKQDAAELSNVHHQLGALQEKATNLENENKSLKE 2794
Query: 1175 E--------LHLQAQKAFQIQEERNVVESEHNV-------------LSSEVENLKSELKE 1059
E L+ +K + + N+ E+++N L ++++LK EL+E
Sbjct: 2795 ENEDLMNQNKQLEKEKQQLLAQNSNLEENKNNQEQSLMNRKKKNDDLLKQIDDLKLELEE 2854
Query: 1058 SKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKN---- 891
K + Q +E+ I + +E++ D+L L+N+N +L +
Sbjct: 2855 LKRNNSQNETKLQ-NANQQIEMMKDQINN---DKEQIKSAQDKLNDLQNKNNELNSNQIV 2910
Query: 890 ----EALYE--YHDYERKN--VSGSRAEAMSVLISKSLGNGRA------NQR------EF 771
+ +YE Y+D + N ++ + +I + N NQR +
Sbjct: 2911 LENQKKMYEGLYNDMKSSNDKLNDENRKKTDQIIDLTKQNAEVSALKLENQRLNSELEKL 2970
Query: 770 QNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXX 591
++ + SS L+ + L+ Q+ LS + + ET+ Q +LE ++L +
Sbjct: 2971 KSNQPVSSNDPELQKQIEELKKQLNNLSNEKKQIETEKNGLQGQIGRLESQNESLIESK- 3029
Query: 590 XXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQX 411
+ +K++N +L+++M + S + + + N + L
Sbjct: 3030 ------------KDMKEQNDKLQAQMDEMRRENNSLRQNQTQLERTNNGLENKVGNLTDQ 3077
Query: 410 XXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXX 231
D S+ E + L ++ K N + Q++ + +L+
Sbjct: 3078 LNQVKNQLSALQDQLKSKENENEKLRNEREKLANEKNSVELQSKDKDAEIIKLKS----- 3132
Query: 230 XXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSM--HDLN 57
D + ++ LN +L + N +L ++ N++ + N
Sbjct: 3133 --------------DAEHLNDKINSLNDEKNKLQQANDKLNDQIEQMKQQINNLTNENKN 3178
Query: 56 GQEQKLKVDEEV 21
+++K K E++
Sbjct: 3179 MEQEKAKNQEKI 3190
Score = 73.2 bits (178), Expect = 5e-10
Identities = 103/506 (20%), Positives = 218/506 (43%), Gaps = 19/506 (3%)
Frame = -1
Query: 2057 EREELNRQLVLLRDDVNHLKEALSMAVDD--RAFMEKQLQDLENQKETVSKELALSVSRE 1884
E EEL ++ L+ + LK+ L + VD M + E++ +EL +
Sbjct: 1861 ENEELKKENQRLKKENAELKKRLGIPVDQIIEGIMNESTASDESEDNKSPEELKREIENL 1920
Query: 1883 QKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIY 1704
+K DLK +E E+N +++ + L +LQ E N++I
Sbjct: 1921 KKQLEDLKNSGSQENVD--------EENNEMKEGADNLIDALQQSVDEK------NKQID 1966
Query: 1703 DLCKLLATKSREVQ------GQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAK 1542
DL + L ++RE++ Q E I +++ N + +A T++V +++ V ++ +
Sbjct: 1967 DLQQKLDDQNREIELLKAKVEQIENINEEEDNEDIVVASTRDV-----ELENVEEESPEE 2021
Query: 1541 VSGIL-EMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQ 1365
L E + ++D + K+ L +L + + E+++ KSE E + +
Sbjct: 2022 AKERLAEQISQLQDKLTEKKKNSLQMKQALASKDAEISKLNEEIEQIKSE----KEDQDK 2077
Query: 1364 EVLRLQAEV-DAIQHILIELKRKNQTLQDESQRN-AKELWNAKARLNNVMSKNINLESQ- 1194
E+ +L E+ +A++ + K+ +Q +E++ + ++ K N+ S+N +L++Q
Sbjct: 2078 ELEKLNNELTEALEKLENGKKKSSQEQNNENEEDFVDDIEKLKEERENLKSENESLKNQA 2137
Query: 1193 --NRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFE 1020
N LK L + + + E++ L SE+ LKSE+ E + R E
Sbjct: 2138 PENEGLKKSLENLKKSNDDLNKSNEDKENKIKELESEISKLKSEINELEQNNKDKDREIE 2197
Query: 1019 ILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGS 840
IL + + +++++ +E + ++ +E NE + N + +
Sbjct: 2198 ILSSKVSSIENVNLDD----DEDDITVVGTRDISVDETIPTDNETETKTEPETNTNTNEN 2253
Query: 839 RAEAMSVLISKSLGNGRANQREFQNKEEDSS-GVDLLKNKCTRLEFQVQKLSEKAEMF-- 669
E +S GN N+ + Q+KE+ + LK + +V L + +
Sbjct: 2254 TNETNEENVSSQEGN---NEEKNQSKEDKKKLRIQQLKQLLASKQGEVDALKSQNDDLKS 2310
Query: 668 --ETKSREAQQMANKLEEMQQTLSDM 597
ET S+ ++ K +E+++ + ++
Sbjct: 2311 ENETLSKSNHELGTKTKELEEEIENI 2336
Score = 72.0 bits (175), Expect = 1e-09
Identities = 139/653 (21%), Positives = 260/653 (39%), Gaps = 87/653 (13%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
+E+ R E K+ +L++ N+ Q+N D E NN + E DN+I L + E
Sbjct: 1911 EELKREIENLKK---QLEDLKNSGSQENVD-----EENNEMKEGADNLIDALQQSVDEKN 1962
Query: 2123 EQRSALQNDMQ-----------SVEQMHAVSQTE-------------------------- 2055
+Q LQ + VEQ+ +++ E
Sbjct: 1963 KQIDDLQQKLDDQNREIELLKAKVEQIENINEEEDNEDIVVASTRDVELENVEEESPEEA 2022
Query: 2054 REELNRQLVLLRDDVN-------HLKEALSMAVDDRAFMEKQLQDLENQKETVSKEL--- 1905
+E L Q+ L+D + +K+AL+ + + + ++++ ++++KE KEL
Sbjct: 2023 KERLAEQISQLQDKLTEKKKNSLQMKQALASKDAEISKLNEEIEQIKSEKEDQDKELEKL 2082
Query: 1904 ------ALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQM 1743
AL K S + +E EE + + E+ + L+ E E SL+ +
Sbjct: 2083 NNELTEALEKLENGKKKSSQEQNNENEEDFVDDIEKLKEERENLKSENE----SLKNQAP 2138
Query: 1742 ENTLLKDGNEKIY----DLCKLLATKSREVQGQQEGI--LKQDINIEDELARTKE----- 1596
EN LK E + DL K K +++ + I LK +IN ++ + K+
Sbjct: 2139 ENEGLKKSLENLKKSNDDLNKSNEDKENKIKELESEISKLKSEINELEQNNKDKDREIEI 2198
Query: 1595 VGRSATDMKKVNSD--------AGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQ 1440
+ + ++ VN D G + + E + + + E N N N+
Sbjct: 2199 LSSKVSSIENVNLDDDEDDITVVGTRDISVDETIPTDNETETKTEPETNTNTNENTNETN 2258
Query: 1439 MVQVALEQMQDTKSELFAE--AEIRAQEVLRL----QAEVDAIQHILIELKRKNQTLQDE 1278
V+ ++ + + E ++R Q++ +L Q EVDA++ +LK +N+TL
Sbjct: 2259 EENVSSQEGNNEEKNQSKEDKKKLRIQQLKQLLASKQGEVDALKSQNDDLKSENETLSKS 2318
Query: 1277 SQR---NAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEH 1107
+ KEL +NN +K + + + E+ + E N E+
Sbjct: 2319 NHELGTKTKELEEEIENINN--NKEGEVIDEKEASDVEVVCSTRDVDFEYENENDPETLK 2376
Query: 1106 NVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL 927
++L S++ L++ KE+K E +L E E+A + R E R+ +E+
Sbjct: 2377 SLLKSKLSELENLQKENKAKEDEITKLNE-------ELAKSEDAKRRELAETAERLNNEI 2429
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSR---AEAMSVLISKSLGNGRANQREFQNKEE 756
L +E +N D + N + + M+VL KS +A + + E
Sbjct: 2430 NTLHDELQNEQNARQKLIEDLQSNNKEPEKDDNGDFMNVLEKKSDEINKALEEILHRQNE 2489
Query: 755 DSSGV---DLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTL 606
+ + + KNK T V L ++ M K + + Q N +++Q+ L
Sbjct: 2490 EIKALRDREAEKNKQT-----VDDLQKQIAMLNNKLKPSDQTDN--DQLQKEL 2535
>ref|XP_005159743.1| PREDICTED: titin isoform X6 [Danio rerio]
Length = 15134
Score = 126 bits (317), Expect = 4e-26
Identities = 169/712 (23%), Positives = 304/712 (42%), Gaps = 41/712 (5%)
Frame = -1
Query: 2258 ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQ 2079
+LQ +L + E + L EA N E I +L K +E E+ + Q+D Q VE+
Sbjct: 4260 DLQHKMFSLDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVEE 4319
Query: 2078 MHAVSQTER-------EELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLE----- 1935
M A Q ER EE NR+ ++L + +KE + DR +EK+ DLE
Sbjct: 4320 MTAQIQKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSK 4379
Query: 1934 --NQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGS 1761
KE + K+ + ++ QK DL+ ++EK + + Q EQ KQ + E+++L
Sbjct: 4380 LLRAKENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTE 4439
Query: 1760 LQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQ---EGILKQDINIEDELARTK-EV 1593
+Q Q E L+ E I L + E+ QQ I++ N +L + K E
Sbjct: 4440 IQNLQQE---LEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEET 4496
Query: 1592 GRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINS--------LRNDAQM 1437
+M+K D + E L MK L+++VL + S L +A
Sbjct: 4497 EEQKQEMEKEKHDFDQSRKSLDEDLKMMK-----LQKQVLEDEKSKLEQMKIELEREAVE 4551
Query: 1436 VQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQ-TLQD--ESQRN 1266
++ E++Q+ + L E +E L E +L E+K N+ TL D + N
Sbjct: 4552 IRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKSN 4611
Query: 1265 AKEL-WNAKARLNNVMSKNINL---ESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVL 1098
+E+ N + +V +K NL E + R L+AE+H Q + +I++E+ +ESE +
Sbjct: 4612 LEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQR---EIEKEKINIESERAAI 4668
Query: 1097 SSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICL 918
+VE+L+ ++ I L + E LD E+ +E L ++ EL
Sbjct: 4669 IKDVEDLQHKI---------------ICLDRDAESLKLDREAFENEKEVLKQMKTELERE 4713
Query: 917 RNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVD 738
+E K+K E HD + R E M+ I K ++ E N E+++ D
Sbjct: 4714 ADEIEKIKLET---QHDRQ-------RVEEMAAQIQK-------DRDEINNLIEETNRKD 4756
Query: 737 LLKNKCTR-LEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXI 561
++ N+ R +E +++ + +M E + + ++ ++L ++++ L
Sbjct: 4757 MVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQ---------KEN 4807
Query: 560 RVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPL------IQXXXXX 399
+ ++KE L + KH+E ++ + D+ T + ++
Sbjct: 4808 TLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEI 4867
Query: 398 XXXXXXKIDTRTSETQEIDTLMDDNRKYW-NRVSHFTKQTQSLQNSVQELQQ 246
++D R SE + T M+D + N K + ++ QE+++
Sbjct: 4868 IMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEK 4919
Score = 101 bits (251), Expect = 2e-18
Identities = 162/831 (19%), Positives = 370/831 (44%), Gaps = 70/831 (8%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLK--IEANNNLLEQKDNIIVELSHKLQE 2130
+E++ +++ +Q E + +QK +D+ + ++ + LE+ ++E+ K +
Sbjct: 10336 EEINHKWKQLQQRIDEFDAQVS--KQKEQDLPKEKGMKEDRKSLEETKANVIEMKTKAEP 10393
Query: 2129 NE---EQRSALQNDMQSVEQMHAVSQTEREELNR---QLVLLRDDVNHLKEALSMAVDDR 1968
E E+ + + + E++ + +TER+EL + +L +R +++H ++ L+ D
Sbjct: 10394 EEIKKEKEKENEEEEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQKKLN---DYM 10450
Query: 1967 AFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALS------EKEESTKNQLLIQTE 1806
+E++ +DLE K + K+ +L + ++ + EK + +L+++ E
Sbjct: 10451 KMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVEVE 10510
Query: 1805 -QNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDI 1629
Q K ++L+ E+L Q E LL K+ + + + E++ ++E + + +I
Sbjct: 10511 EQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKKVDEEIKKERETLREMEI 10570
Query: 1628 NIEDELARTK----EVGRSATDMKKVNSDAGAKVSGILEMLLPMK---DDVFSLKEEVLG 1470
+++ E + E R D++K+++D I E L +K D + +EE+
Sbjct: 10571 HLKKEKEELRSIIEETQRRKEDLEKMSTD-------INEQKLHLKNQRDLLEQEREEINH 10623
Query: 1469 NINSLRN-----DAQM-----------VQVALEQMQDTKSELF-AEAEIRAQEVLRLQAE 1341
+ L+ DAQ+ ++ + +++TK+ + + + QE+++ + E
Sbjct: 10624 EMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEE 10683
Query: 1340 VDAIQ-HILIELKRKN-QTLQDESQRNAKELWNAKARLNNVMSKNINLESQN-RSLKAEL 1170
D + +++E++R+ ++ E +R E+ + + +LN+ K I E ++ +K+E+
Sbjct: 10684 EDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLND-DKKIIEQEKEDLEKMKSEI 10742
Query: 1169 HLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDL-EGYFLRLFEILLGQHVEV 993
Q Q Q++EER+ E ++ + +++E + +++ SK++ + +++ E ++
Sbjct: 10743 MTQRQ---QMEEERS--ELDNKIKQTDLE--RHDIENSKEIVQKLMVKVEEQRKDIRLQK 10795
Query: 992 ASLDIESCRFAEEKLMRILDELICLRNENAKLK---------NEALYEYHDYERKNVSGS 840
LDIE + A+E+ + ++ L+NEN ++K E L E + RK
Sbjct: 10796 EELDIERQKIADEQGL-VVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEM 10854
Query: 839 RA-------------EAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQV 699
R+ E MS ++K NQR+ +E + + +K T+L+ ++
Sbjct: 10855 RSVIEETQRRKKEDLEKMSTDVNKQ-NQDLMNQRDLLKQEREE-----INHKWTQLQQRI 10908
Query: 698 Q----KLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENT 531
++S++ E TK ++ ++ LEE + + +M + + ++E
Sbjct: 10909 DEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKE-EEEVM 10967
Query: 530 RLRSEM-KGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSET 354
R + EM K EL +S R S I DD +I+ +I + +
Sbjct: 10968 RAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQM 11027
Query: 353 QEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSI 174
+E + +D N++ + ++NS + +Q+ M +
Sbjct: 11028 EEERSELD------NKIKQTDLERHDIENSKEIVQKL-------------------MVEV 11062
Query: 173 EKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEEV 21
E+Q K++ + +L ++ + G N N E+ ++DEE+
Sbjct: 11063 EEQRKDIRLQKEELDIERQKIADEQ--GLVVQNKAKLQNENERIKEMDEEI 11111
Score = 100 bits (250), Expect = 2e-18
Identities = 148/763 (19%), Positives = 321/763 (42%), Gaps = 12/763 (1%)
Frame = -1
Query: 2276 EKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQND 2097
E QH + E A QK+ D KI NNL+E+ + + L+ K ++ E++ ++Q+D
Sbjct: 5596 ETQHDRQRVEEMTAQIQKDRD---KI---NNLIEETNRKDMVLNEKNRDIEKKIKSIQSD 5649
Query: 2096 MQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETV 1917
+E+ + + E+ +L +++D+ KE + A ++K+ +DLE E +
Sbjct: 5650 KDMLEK----EKHDLEKTRSELYKVKEDLEKQKE------NTLAQIQKEREDLEKMNENI 5699
Query: 1916 SKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQME- 1740
++E+ +E+++ L + + +N +Q E K+ E+ I K L +Q E
Sbjct: 5700 TREMHEIKHQEEQMNQKQDELDQLKTEIQN---LQQELEKEKEI-IMKARSQLDRRQSEL 5755
Query: 1739 ---NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMK 1569
T + D E + + K L E++ Q++ + K+ N++ E + K
Sbjct: 5756 DKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQK 5815
Query: 1568 KVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELF 1389
+V + K+ + L DD+ +KEE +N Q+++ E+++ + ++
Sbjct: 5816 QVIEEEKNKLEQMKIELEREADDIRKIKEET-------QNKRQILEKMAEELKKERKDVA 5868
Query: 1388 AEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNI 1209
AE +E L A + + +L+++ L++ + +K+ + + + + +
Sbjct: 5869 HLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLRED 5928
Query: 1208 NLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLR 1029
LE L+AE+H Q + + E++ +E E + +VE+L+S++
Sbjct: 5929 ELE----QLQAEIHKQQS---ETEIEKSNIERERAAIIKDVEDLQSKI------------ 5969
Query: 1028 LFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNV 849
I L + E LD E+ +E+L ++ EL +E K+K E +ER+ V
Sbjct: 5970 ---ISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLET-----QHERQRV 6021
Query: 848 SGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMF 669
A+ M + ++ + + K+E D + L+ ++ + + ++
Sbjct: 6022 EEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVL 6081
Query: 668 ETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRV-RSLKKENTRLRSEMKGELTPS 492
E + + +QM LE +S + ++ +LK+E L E+K
Sbjct: 6082 EEEKNKLEQMKIGLEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIK------ 6135
Query: 491 RSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYW 312
R+ + +I + +E +Q + R + +++I+ + ++ K
Sbjct: 6136 -----RKNQVLDKIKVANESTLADLQKEKRILE------EMRENISKQIEDIENEKEKSK 6184
Query: 311 NRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQL 132
R K +Q E+ + + M ++K+ +++ + + ++
Sbjct: 6185 LREDELKKLQTEVQKQQSEIDMEKTNIESERAAMIREKQNM-MTELKKKSEDVEMQMKEI 6243
Query: 131 VE-----HNTR--LKKDVKFGFAWANSMHDLNGQEQKLKVDEE 24
+ HN R LKKDV+ + + + LK+D+E
Sbjct: 6244 LTEKELLHNDRNLLKKDVE---DLQQKLMSIERDSESLKLDKE 6283
Score = 98.2 bits (243), Expect = 1e-17
Identities = 169/821 (20%), Positives = 350/821 (42%), Gaps = 72/821 (8%)
Frame = -1
Query: 2282 EEEKQHTI-ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
E++K++T+ ++Q+ L + NE+I ++ + EQ ++ K E ++ ++ +
Sbjct: 5675 EKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQ-------MNQKQDELDQLKTEI 5727
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
QN Q +E+ + R +L+R+ L ++ + + ++R ++K +++E QK
Sbjct: 5728 QNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQK 5787
Query: 1925 ETVSKELALSVSREQKLASDLKALS------EKEESTKNQLLIQTE-------------Q 1803
+ + KE + L DLK + E+E++ Q+ I+ E Q
Sbjct: 5788 QEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQ 5847
Query: 1802 NKQ--LELEIEKL--------YGSLQMKQMENTL--LKDGNEKIYDLCKLLATKSREVQG 1659
NK+ LE E+L + + K+ +N+L +K NE + L KS ++
Sbjct: 5848 NKRQILEKMAEELKKERKDVAHLAEDTKREKNSLDEMKVANES--SMADLQKEKS-NLEE 5904
Query: 1658 QQEGILKQDINIEDE----LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFS 1491
+E I KQ +IE E R E+ + ++ K S+ + S I + DV
Sbjct: 5905 MKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVED 5964
Query: 1490 LKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIE 1311
L+ +++ SL DA+ +++ E ++ K EL Q L+ E D I+ I +E
Sbjct: 5965 LQSKII----SLDRDAESLKLDREAFENEKEEL-------KQMKTELEREADEIEKIKLE 6013
Query: 1310 LKRKNQTLQDESQRNAKELWNAKARL--NNVM---------SKNINLESQNRSLKAELHL 1164
+ + Q +++ + + + N + +L N VM K +++ +SL +L +
Sbjct: 6014 TQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKM 6073
Query: 1163 QAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASL 984
+ ++EE+N +E L E + + S++KE E L L + E +
Sbjct: 6074 MKAQKQVLEEEKNKLEQMKIGLEREADEI-SKIKEETQNERQNLEKMANALKEEREYLAE 6132
Query: 983 DIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKS 804
+I ++ ++LD++ K+ NE+ E++ + E M ISK
Sbjct: 6133 EI-------KRKNQVLDKI--------KVANESTLADLQKEKRIL-----EEMRENISKQ 6172
Query: 803 LGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETK--------SREA 648
+ + +N++E S L +++ +L+ +VQK + +M +T RE
Sbjct: 6173 I-------EDIENEKEKSK---LREDELKKLQTEVQKQQSEIDMEKTNIESERAAMIREK 6222
Query: 647 QQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRS-LKKENTRLRSEMKGELTPSRSFKHRE 471
Q M +L++ + + R+ LKK+ L+ ++ S S K +
Sbjct: 6223 QNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIERDSESLKLDK 6282
Query: 470 GSFIKEINIGDEDDTPL------IQXXXXXXXXXXXKIDTRTS----ETQEIDTLMDDNR 321
+F E + T L I+ +++ +T+ E +EI+TL+++ +
Sbjct: 6283 EAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIK 6342
Query: 320 KYWNRV----SHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDM--NSIEKQLK 159
K + + + K+ +++++ +L++ I N++EK K
Sbjct: 6343 KKRDIIDESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQQKRNALEKMSK 6402
Query: 158 ELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLK 36
E++ M+L + KK+++ MH ++Q+ K
Sbjct: 6403 EISRDRMKLEDE----KKEIQLAREELERMHGDMQRQQEAK 6439
Score = 97.1 bits (240), Expect = 3e-17
Identities = 121/592 (20%), Positives = 267/592 (45%), Gaps = 29/592 (4%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQ----KDNIIVELSHKLQ 2133
E+ ++ EE + L++ AL+++ ED+ + + NN +L++ ++ + ++ +
Sbjct: 4551 EIRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKS 4610
Query: 2132 ENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK 1953
EE R + + VE + +EL + + +++ +RA + K
Sbjct: 4611 NLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIK 4670
Query: 1952 QLQDLENQKETVSKEL-ALSVSR-----EQKLASDLKALSEKEESTKNQLLIQTEQNKQL 1791
++DL+++ + ++ +L + R E+++ +K E+E ++ ++T+ ++Q
Sbjct: 4671 DVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIKLETQHDRQ- 4729
Query: 1790 ELEIEKLYGSLQMKQME-NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDE 1614
+E++ +Q + E N L+++ N K D+ +L K+R+++ + + I +D
Sbjct: 4730 --RVEEMAAQIQKDRDEINNLIEETNRK--DM--VLNEKNRDIEEKIKSIQSD----KDM 4779
Query: 1613 LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
L + K D++K S+ L +K+D+ KE L I R D
Sbjct: 4780 LEKEKH------DLEKTRSE-----------LYKVKEDLEKQKENTLAEIQKERED---- 4818
Query: 1433 QVALEQMQDTKSELFAEAEIRAQEVLRLQAEVD----AIQHILIEL-KRKNQTLQDESQR 1269
LE+M + + E + + +++ + Q E+D IQ++ EL K K ++D SQ
Sbjct: 4819 ---LEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQL 4875
Query: 1268 NAK--ELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLS 1095
+ + EL + +N++M N Q K E+ Q Q ++++ER+ ++ L
Sbjct: 4876 DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQ---EMEKERDNMDQSRKSLD 4932
Query: 1094 SEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLR 915
+ + +K + K+ + E L +I L + + S E + ++L ++ +ELI +
Sbjct: 4933 EDQKKMKLQ-KQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREK 4991
Query: 914 NENAKLKNEALYEYHDYERKNVSGSRAEA---MSVLISKSLGNGRANQREFQNKEEDSSG 744
A L + E + V+ + A I + + + +E+ + E++ S
Sbjct: 4992 ESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENISKLKEYIDNEKEKS- 5050
Query: 743 VDLLKNKCTRLEFQVQKLSEKAEMFETK--------SREAQQMANKLEEMQQ 612
L +++ +L+ +VQK K +M +T RE Q M +L++ +
Sbjct: 5051 -KLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKKSE 5101
Score = 96.7 bits (239), Expect = 4e-17
Identities = 128/572 (22%), Positives = 261/572 (45%), Gaps = 11/572 (1%)
Frame = -1
Query: 2282 EEEKQHTIELQEN-FNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
+E+ HT EL+++ A+ QK E+I + +E+ N EL + + ++ L
Sbjct: 12336 KEQMGHTEELEKDELIAILQKREEIVKRH------MEEIQNQREELQKEKDQFGNMQAEL 12389
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
Q +E + +ER+ELN V L E + ++ R E L+D+ +K
Sbjct: 12390 QKGQLEMEMHQLMLNSERDELNGMRVNLEKQKEEF-ELMQQNLESRR-PESLLEDILKEK 12447
Query: 1925 ETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQ 1746
+ V +E+A +S+EQ E +N I +E K++E +I+++ G ++ KQ
Sbjct: 12448 KRV-EEMAAQLSKEQ-------------EEFRN---IMSETIKRME-KIKQIEGEIKTKQ 12489
Query: 1745 MENTLLKDGNEKIYDLCK-LLATKSREVQGQQEGI--LKQDINIE-DELAR-TKEVGRSA 1581
+E L++ +K D K + +++E+Q ++E + +K +I+IE DE+ + K+ +
Sbjct: 12490 IEMACLEELKQKELDEQKNMRECENQELQMRREELAKMKTEIDIERDEIQKLRKQYEKEK 12549
Query: 1580 TDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTK 1401
+++++ D L+ P K D +E+ G I+SL+ + + ++ +Q+
Sbjct: 12550 CELEQIKPD--------LQKREPEKIDAEVQHDEIHGGIDSLKEEREEIEKMKADLQNKL 12601
Query: 1400 SELFAEAEIRAQEVLRLQAEVDAIQHILIELK--RKNQTLQDESQRNAKELWNAKARLNN 1227
E +I +E L+ + I+ + +E + ++ LQDE + L K + N
Sbjct: 12602 REAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIEAILKVTKKQKNY 12661
Query: 1226 VMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDL 1047
+ N NL + L+ + ++ ++ ++ E H S++E ++E K +
Sbjct: 12662 LEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEFH---MSKMEEREAERKTIE-- 12716
Query: 1046 EGYFLRLFEILLGQHVEVASLDIESCRFAEE--KLMRILDELICLRNENAKLKNEALYEY 873
R+ + + +H ++ E EE K R+L+E + NE K K+E +E
Sbjct: 12717 -----RVMDEMAEEHEKIKKEREELVNMEEEIKKQRRVLEESM---NEMTKKKSELQHER 12768
Query: 872 HD-YERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQ 696
+ Y++K + + +I+ +R Q+KE++ +LK + +
Sbjct: 12769 SELYKQK-------QQLEDMIASESKRDVDTERSRQDKEDE----QILKREREEIADMKD 12817
Query: 695 KLSEKAEMFETKSREAQQMANKLEEMQQTLSD 600
+L ++ E ET + +E+MQ L+D
Sbjct: 12818 QLLKEKEDVETTKERINREKEHIEKMQSQLND 12849
Score = 95.9 bits (237), Expect = 7e-17
Identities = 121/615 (19%), Positives = 259/615 (42%), Gaps = 8/615 (1%)
Frame = -1
Query: 2291 RLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRS 2112
R+ E + Q + + +E+ ++ ED E N+LE K E K +E EE+
Sbjct: 11462 RIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQ 11521
Query: 2111 ALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLEN 1932
++ ++ + + E E++ QL +R +++H ++ L+ DD+ +E++ +DLE
Sbjct: 11522 EMRVKVE-------MERKEIEQIKSQLERVRSEMDHEQKKLN---DDKKMIEQEKEDLEK 11571
Query: 1931 QKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQM 1752
K + K+ +L +K ++ +N E ++L +E+EK +Q
Sbjct: 11572 MKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENS----KEIVEKLMVEVEKQKHEIQF 11627
Query: 1751 KQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDM 1572
++ E L +KI D LL E Q + E I + D I+ E KE+ +
Sbjct: 11628 QKEE---LDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNLQKE 11684
Query: 1571 KKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSEL 1392
K+ + E L M D+ K++++ + L+ + + + L Q+Q E
Sbjct: 11685 KEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEF 11744
Query: 1391 FAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKN 1212
+ I + + E+D L + ++ +++ +E+ R EL +
Sbjct: 11745 ETTSNILVTTKMEEKTEMD---EKLQQAIKEYESIIEETNRKRTELEEIE---------- 11791
Query: 1211 INLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFL 1032
++ QN++++ L +++ER E E L + ++L+ ++ E D E
Sbjct: 11792 VDQSQQNKNVETMKDL-------LEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSK 11844
Query: 1031 RLFEI---LLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYE 861
R + LL Q + +E +M+ +EL L+ E KNE + E
Sbjct: 11845 RSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKEIQNQKNEMEEIKCELE 11904
Query: 860 RKNVSGSRAEAMSVLISKSLGNGRANQREFQ----NKEEDSSGVDLLKNKCTRLEFQVQK 693
K + + + + +SL ++ + + E+ ++ ++ K ++ +
Sbjct: 11905 TKRIEIIKEQKR---LEESLNTVNEERQYLEIVRVDYEKHQQQIEEMRVKTKMERDELDQ 11961
Query: 692 LSEKAEMFETKSREAQQMANKLE-EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSE 516
L K M ++ ++ M L+ EM+QT ++ ++++ KK+ ++E
Sbjct: 11962 LMAKMLMDRKENERSKDMIGLLKKEMEQTKFNLDAQEEELKLEKQKIQNEKKDLEMFKAE 12021
Query: 515 MKGELTPSRSFKHRE 471
+K E + ++ K ++
Sbjct: 12022 IKREASEVKTLKEQQ 12036
Score = 94.7 bits (234), Expect = 2e-16
Identities = 148/745 (19%), Positives = 307/745 (41%), Gaps = 60/745 (8%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQ------ENFNALRQKNED-----ICLKIEANNN-----LLEQK 2169
E+ R EE ++ + LQ EN A Q+ ED I +KI+ L ++
Sbjct: 8911 EMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQLDKET 8970
Query: 2168 DNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEAL 1989
+ E+ K+++ E + + ++ Q +E + + E++EL ++ L D + L
Sbjct: 8971 KRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREK 9030
Query: 1988 SMAVDDR---AFMEKQLQDLENQKETVSKELALSVS----------REQKLASDLKALSE 1848
++R ++ QL+DL + E V ++L L S ++Q+L + ++
Sbjct: 9031 QETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENK 9090
Query: 1847 KEESTKNQLLIQTEQNKQ-LELEIEKLYGSL-QMKQMENTL--LKDGNEKI--------Y 1704
KE+ + Q +TEQ KQ LE+ K+ +M + L KD EKI +
Sbjct: 9091 KEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDELEKIAYKTNKERH 9150
Query: 1703 DLCKLLATKSREVQG-QQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAK---VS 1536
++ ++ A ++Q +Q+G + QD E + + R ++K N++ + ++
Sbjct: 9151 EVEQMQAELHSQIQAIEQQGQIMQDKQNHLE-EKELSIQRKEEEIKIGNTEFQIEQEHLN 9209
Query: 1535 GILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSEL--FAEAEIRAQE 1362
+LE + D+ ++ ++ N D ++++ ++++ K +L + E + E
Sbjct: 9210 NVLEETNKRQHDLEVMRADIELNKQKNNKDFELLEKIRSELENEKYDLQIWTEQQKHLVE 9269
Query: 1361 V--LRLQAEVDAIQHILIELKRKNQTLQDES---QRNAKELWNAKARLNNVMSKNINLES 1197
V L+ E + ++ + IEL+ K + + E R E+ K ++
Sbjct: 9270 VQLQELEKEKERLEKMEIELQSKREQTEKEKADLNRVNAEIQREKQVIDKKRHMTNRAME 9329
Query: 1196 QNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEI 1017
+ ++K EL + +K IQ E+ +E E ++ E ENL L+E K +
Sbjct: 9330 ELETIKTELKERQEK---IQTEQEKLEEEKLLVQIEAENLNKVLEEIKRQQ--------- 9377
Query: 1016 LLGQHVEVASLDI----ESCRFAEEKLMR---ILDELICLRNENAKLKNEALYEYHDYER 858
+ +E++ D+ E C A E+ R ++E I NENAK + ER
Sbjct: 9378 ---EKLEISEADLKVMKEQCENAREETERKKCDIEEQI-QNNENAK-------HLLEQER 9426
Query: 857 KNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKA 678
K++ + E + + +K LL+ K + Q L ++
Sbjct: 9427 KDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEKEK 9486
Query: 677 EMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELT 498
E K + + N+++ + + ++ + + +E+ R +E KG+L
Sbjct: 9487 EDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGDLE 9546
Query: 497 PSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRK 318
R+ ++ I+E+ + + + + +ID + +++ R
Sbjct: 9547 IMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKERN 9606
Query: 317 YWNRV-SHFTKQTQSLQNSVQELQQ 246
++ S Q Q +++ EL Q
Sbjct: 9607 DLEKMKSELMTQRQQMEDERSELDQ 9631
Score = 94.0 bits (232), Expect = 3e-16
Identities = 135/605 (22%), Positives = 286/605 (47%), Gaps = 41/605 (6%)
Frame = -1
Query: 2291 RLYEEEKQHTIELQENF-NALRQKNEDICLKIEANNNLLEQKDNIIVE---LSHKLQENE 2124
R+ E + Q + +E+ N + + E CL+ E N ++E K +E ++ K++E +
Sbjct: 9779 RIDEFDAQVRKQKEEDLTNQKKMEEERKCLE-EVNGKIIEMKTKAELEHHEINQKIEELQ 9837
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNR---QLVLLRDDVNH----LKEALSMAVDDRA 1965
+ + + + E M + ERE+L++ +LV + +V+H L + + M ++
Sbjct: 9838 TLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKE 9897
Query: 1964 FMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLEL 1785
+EK ++ QK+ + KE + ++ Q+ + + + +E + + EQ +++L
Sbjct: 9898 DLEKMKSEIMTQKQEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRHEIQL 9957
Query: 1784 EIEKLYGSLQMKQMENTL-------LKDGNEKIYDLCKLLATKSREVQGQQEGILKQD-- 1632
+ E+L Q E L L++ NE+I ++ +++ K RE + E L+++
Sbjct: 9958 QKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEVI-KKERETLKEMEAHLEKEKE 10016
Query: 1631 --INIEDELARTKE-VGRSATDMKKVNSDAGAKVSGILEM----------LLPMKDDVFS 1491
+I +E R KE + + +TD+K+ N D K +LE L + D F
Sbjct: 10017 EMKSITEETRRQKEDLEKMSTDIKEQNQDL-MKQRDLLEQEKEDINHEWTQLQQRIDEFD 10075
Query: 1490 L-----KEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQ 1326
KEE L ++ + + +LE+ + E+ +AE+ + + + E +
Sbjct: 10076 AQVSKQKEEDLTKQKEMKEERK----SLEETKARIIEMKTKAELEDIKKEKEKEEEEEEM 10131
Query: 1325 HILIELKRKN-QTLQDESQRNAKELWNAKARLNNVMSKNINLESQN-RSLKAELHLQAQK 1152
+ +E+ K ++ E +R E+ + + +LN+ K I E QN +K+E+ Q Q
Sbjct: 10132 RVKVEMDGKELDRIKSELKRERSEIDHEQKKLND-DKKIIEQEKQNLEKMKSEIMKQRQ- 10189
Query: 1151 AFQIQEERNVVESEHNVLSSEVENLKSELKESKDL-EGYFLRLFEILLGQHVEVASLDIE 975
Q++EER+ E E+ + + +E K +++ SK++ + + + E + LDIE
Sbjct: 10190 --QMEEERS--ELENKIKQTYIE--KCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIE 10243
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGN 795
+ A+E+ + I ++ L+NEN +++N L E ER+ + + M + K
Sbjct: 10244 RQKIADEQDLLIQNKSE-LQNENERIRN--LNEIIKKERETL-----KEMEAHLEKKKEE 10295
Query: 794 GRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQ 615
++ E + +ED L+ T + Q + L + ++ E +E +++ +K +++Q
Sbjct: 10296 IKSVSEETRRLKED------LEKMSTDVNKQNKDLMNQRDLLE---QEREEINHKWKQLQ 10346
Query: 614 QTLSD 600
Q + +
Sbjct: 10347 QRIDE 10351
Score = 93.2 bits (230), Expect = 4e-16
Identities = 143/645 (22%), Positives = 276/645 (42%), Gaps = 45/645 (6%)
Frame = -1
Query: 2276 EKQHTIELQENFNALRQ-KNEDICLKIEANNNLLEQKDNIIV-ELSHKLQENEEQRSALQ 2103
++ I+ ++ LR+ K + + +I ++ K +II E + ++N++ + L
Sbjct: 3562 KQNEMIDSEKKKMILREDKLQQMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMTELT 3621
Query: 2102 NDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKE 1923
+ VE TE+E L LL+ DV +L++ L + D +++ + LEN+KE
Sbjct: 3622 KQSEDVEIQMKEVLTEKELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKE 3681
Query: 1922 TVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQ--------NKQLELEIEKL- 1770
V K++ + E + +K ++ E ++ Q ++ N + EI +
Sbjct: 3682 -VLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIK 3740
Query: 1769 YGSLQMKQMENTL------LKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELA 1608
Y QMKQ ++ L +++ +++ +++ E+ +Q + KQ N+ D +
Sbjct: 3741 YQEKQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLKQSELDKQQTNMNDIIE 3800
Query: 1607 RTK-----------EVGRSATDMKKVNSDAGAKVSGILEMLLPMK--DDVFSLKEEVLGN 1467
K E+ +++K D + + E L MK VF ++ L
Sbjct: 3801 TMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVFEEEKNKLEQ 3860
Query: 1466 IN-SLRNDAQMVQVALEQMQDTKSEL---FAEAEIRAQEVLRLQAEVDAIQHILIELKRK 1299
+ L +A ++ E++Q+ + L E + + L + Q IL E+K
Sbjct: 3861 MKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVA 3920
Query: 1298 NQTLQDESQR---NAKEL-WNAKARLNNVMSKNINL---ESQNRSLKAELHLQAQKAFQI 1140
N++L E Q+ N +E+ N + +V +K NL E + L+AE+H Q + +I
Sbjct: 3921 NESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLREDELGQLQAEIHKQQR---EI 3977
Query: 1139 QEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFA 960
++E++ +ESE + VE+L+ ++ I L + E LD E+
Sbjct: 3978 EKEKSNIESERAAIIKIVEDLQHKI---------------ISLDRDAESLKLDREAFENE 4022
Query: 959 EEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQ 780
E L ++ EL +E K+K E +E R E M+ +++ N R
Sbjct: 4023 REVLKQMKTELERETDEIEKIKLETQHE----------RQRVEEMTADFMETMNNERKQL 4072
Query: 779 REFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSD 600
+NKEE ++ + ++ + L + +M + + + ++ NKLE+M+ L
Sbjct: 4073 N--KNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIELE- 4129
Query: 599 MXXXXXXXXXXXIRVRSLKKE--NTRLRSE-MKGELTPSR-SFKH 477
+R +K+E N R R E M EL + SF H
Sbjct: 4130 ---------KEADEIRKIKEETQNERQRLEKMTEELKKEKESFTH 4165
Score = 92.4 bits (228), Expect = 8e-16
Identities = 119/631 (18%), Positives = 280/631 (44%), Gaps = 68/631 (10%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE- 2124
E + + +Q E+++ N L +K EDI + + + + +E+ + E E
Sbjct: 294 ETQKAKDLMEQMKAEIEDEKNELEKKKEDIKRQRDQFEQIKLDLQQVKMEMEQRWHETEK 353
Query: 2123 ---EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFM-- 1959
EQR+ +Q + + ++ + Q REE+ R + + + + + A+++ +
Sbjct: 354 EGLEQRAVIQREKEQLKYLQDEIQRVREEVERNREFSKQEHARISQLRAQALEENNLIEN 413
Query: 1958 --------EKQLQDLENQKETVSKELALS---VSRE----QKLASDLKALSEKEESTKNQ 1824
EK L++++++ E +EL ++ V +E ++ D+++ E ++
Sbjct: 414 KWHDILRKEKDLEEMKHEIERGREELVMNGELVKKEWEKIEQAKVDIQSHMISMEGRVDE 473
Query: 1823 LLIQTEQNKQLELEIEKLYGSLQMKQMENT--LLKDGNEKIYDLCKLLATKSREVQGQQE 1650
+ +TE+ K ++ E+++ +L+ KQ ++T ++ K Y+ + T+ E + + +
Sbjct: 474 IKRETERLKHIKTEMQRDKDALE-KQKDDTRKAKEEAERKRYE----IVTEELEHRARLQ 528
Query: 1649 GILKQDINIEDELARTKEVGRSATDMKK-------------------VNSDAGA---KVS 1536
+ NI E+ R +V ++ +K VN++ A +++
Sbjct: 529 RERDELENIRAEMQRVNDVEKAKILKEKEESIRIREEARQERETTELVNAEIKAEKERLN 588
Query: 1535 GILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVL 1356
E +L + ++ +K E L + N + E+M+ K+E+ + E ++V
Sbjct: 589 QRQEEMLRERQEIERIKHETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVE 648
Query: 1355 RLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNR---- 1188
+Q + ++ +EL+ + + L+ + ++E+ A+ N ++ +ES+ R
Sbjct: 649 EIQKTKEQMEEAKVELEEEREDLERKRDLVSREIEQAEFLRNEILRVKEEMESRWRETET 708
Query: 1187 ---SLKAELHLQAQKAFQIQEE-----RNVVESEHNVL--SSEVENLKSELKESKD---L 1047
L+A+ + ++ +++EE +N+ ES+ ++ ++ LK E++E K +
Sbjct: 709 EEVELRAKTQHELERLEKLREETERSQKNIEESKIELMLWKESLDKLKGEMEEDKHVVIM 768
Query: 1046 EGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNE----NAKLKNEALY 879
+ + E L +E ++ + EK+ LDE+ +RNE +A++++
Sbjct: 769 QMNEAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQHAEMEDWFRV 828
Query: 878 EYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQV 699
+ E N++ +L+ K + + +R ++ E D ++ K LE Q+
Sbjct: 829 VNKEKEEANLAKLAVHEAEMLLKKQM--EESEKRRYEMITEALEQRDEIQKKAEELE-QI 885
Query: 698 QKLSEKAEMFETKSR--EAQQMANKLEEMQQ 612
K ++A K R E + + LE+ QQ
Sbjct: 886 NKEIQRARQELEKMRYFEKESLQKMLEDTQQ 916
Score = 92.0 bits (227), Expect = 1e-15
Identities = 142/718 (19%), Positives = 312/718 (43%), Gaps = 33/718 (4%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEAN----NNLLEQKDNIIVELSHKLQ 2133
E+ R +E ++ +E Q + RQ+ E++ +I+ + NNL+E+ + + L+ K +
Sbjct: 4709 ELEREADEIEKIKLETQHD----RQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNR 4764
Query: 2132 ENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK 1953
+ EE+ ++Q+D +E+ + + E+ +L +++D+ KE + A ++K
Sbjct: 4765 DIEEKIKSIQSDKDMLEK----EKHDLEKTRSELYKVKEDLEKQKE------NTLAEIQK 4814
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEK 1773
+ +DLE E +++E+ +E+++ L + + +N +Q E K+ E+ I K
Sbjct: 4815 EREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQN---LQQELEKEKEI-IMK 4870
Query: 1772 LYGSLQMKQME----NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 1605
L ++Q E T + D E + + K L E++ Q++ + K+ N++
Sbjct: 4871 DRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKS 4930
Query: 1604 TKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVA 1425
E + K++ + K+ + L D++ +KEE +N Q ++
Sbjct: 4931 LDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEET-------QNKRQRLEKM 4983
Query: 1424 LEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNA 1245
E++ K L AE E L A + + +L+R+ L +E + N +L
Sbjct: 4984 TEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSIL-EEMRENISKL--- 5039
Query: 1244 KARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL 1065
K ++N K+ E + + L+ E+ Q K I E+ +ESE + E +N+ +EL
Sbjct: 5040 KEYIDNEKEKSKLREDELKKLQTEVQKQQSK---IDMEKTNIESERAAMIREKQNMMTEL 5096
Query: 1064 -KESKDLEGYFLRLFEILLGQHV-----EVASLDIESCR----FAEEKLMRILDELICLR 915
K+S+D+E +++ EIL + + ++ + D+E+ + E R+ +
Sbjct: 5097 KKKSEDVE---IQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFE 5153
Query: 914 NEN---AKLKNEALYEYHDYERKNV----SGSRAEAMSVLISKSLGNGRANQREFQNKEE 756
NE ++K + + + E+ + R E M+ I K + + N E
Sbjct: 5154 NEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQK-------ERDKINNLIE 5206
Query: 755 DSSGVDLLKNKCTR-LEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXX 579
+++ D++ N+ R +E +++ + +M E + ++ ++L ++++ L
Sbjct: 5207 ETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQ------ 5260
Query: 578 XXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPL------I 417
+ ++KE + + KH+E ++ + D+ T + +
Sbjct: 5261 ---KENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQEL 5317
Query: 416 QXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYW-NRVSHFTKQTQSLQNSVQELQQ 246
+ + D R SE + T M+D + N K + ++ QE+++
Sbjct: 5318 EKEKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEK 5375
Score = 91.7 bits (226), Expect = 1e-15
Identities = 146/693 (21%), Positives = 299/693 (43%), Gaps = 77/693 (11%)
Frame = -1
Query: 2282 EEEKQHTI-ELQENFNALRQKNEDICLKI-------EANNNLLEQKDNIIVELSHKLQEN 2127
E++K++T+ E+Q+ L + NE+I ++ E N ++ D + E+ + QE
Sbjct: 4802 EKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQEL 4861
Query: 2126 EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL 1947
E+++ + D ++ + EL++Q + D + +K D+ ME+Q
Sbjct: 4862 EKEKEIIMKDRSQLD-------LRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQK 4914
Query: 1946 QDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLY 1767
Q++E +++ + + S+ +QK K + E+E++ Q+ I+ E+ EI K+
Sbjct: 4915 QEMEKERDNMDQS-RKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREAD---EISKIK 4970
Query: 1766 GSLQ-----MKQMENTLLKD------------GNEKIYDLCKL-----LATKSRE---VQ 1662
Q +++M L+++ +KI D K+ +A RE ++
Sbjct: 4971 EETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILE 5030
Query: 1661 GQQEGI--LKQDINIEDELARTKE-----------VGRSATDMKKVN--SDAGAKVSGIL 1527
+E I LK+ I+ E E ++ +E +S DM+K N S+ A +
Sbjct: 5031 EMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQ 5090
Query: 1526 EMLLPMK---DDVFSLKEEVLGNINSLRNDAQMVQVALEQMQ--------DTK-----SE 1395
M+ +K +DV +E+L L ND +++ +E +Q D+K E
Sbjct: 5091 NMMTELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDRE 5150
Query: 1394 LFA-EAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMS 1218
F E E Q LQ + D I+ I +E + Q +++ + + KE +
Sbjct: 5151 AFENEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNR 5210
Query: 1217 KNINLESQNRSLKAELHLQAQKAFQIQEERNVVESE-HNV--LSSEVENLKSELKESKDL 1047
K++ L +NR ++ +K IQ +++++E E HN+ SE+ +K +L++ K+
Sbjct: 5211 KDMVLNEKNRDIE-------EKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKEN 5263
Query: 1046 EGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYE--- 876
++ + + E + ++ + EE++ + DEL L+ E L+ E E
Sbjct: 5264 TLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEI 5323
Query: 875 -YHDYERKNVSGSRAEAMSVLISKSLGNGRANQREF-QNKEEDSSGVDLLKNKCTRLEFQ 702
D + ++ S + ++ + + +++ ++KEE ++ + +
Sbjct: 5324 IMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQS 5383
Query: 701 VQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLR 522
+ L + +M + + + ++ NKLE+M+ L +R +K+E R
Sbjct: 5384 RKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELE----------READEIRKIKEETQNER 5433
Query: 521 ---SEMKGELTPSR-SFKHREGSFIKEINIGDE 435
+M EL + SF H KE I D+
Sbjct: 5434 QSLEKMTEELKKEKESFTHLAEDTKKEQEILDK 5466
Score = 91.3 bits (225), Expect = 2e-15
Identities = 159/754 (21%), Positives = 300/754 (39%), Gaps = 22/754 (2%)
Frame = -1
Query: 2297 VSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQ 2118
++R E+ K+ L E F AL K E I +++ + EL + ++ E+Q
Sbjct: 2582 LNRELEKIKEKKTILAEEFEALDDKKEMI-------GKEMQRLGKMKAELQKEAEDTEKQ 2634
Query: 2117 RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDL 1938
R + ND ++ E+M Q E++++ +RD+ +L+ DR +EK+ DL
Sbjct: 2635 RRDIDNDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLESDRDTLEKERFDL 2694
Query: 1937 ENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQ-TEQNKQLELEIEKLYGS 1761
E K +++K L ++ ES Q IQ E K+ E+ +E+L +
Sbjct: 2695 EKTK------------------TEMKDLEKQLESQSRQHEIQLVEIQKEREI-LEQLKIN 2735
Query: 1760 LQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIE---DELART---- 1602
L ++ + +D EK + + + E Q ++EGI K + I+ DEL +T
Sbjct: 2736 LSKQKEDLEKERDCFEK--EKADISLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNV 2793
Query: 1601 -KEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVA 1425
KE+ + K++ D K+ I L D ++++ N RN+ +MV
Sbjct: 2794 VKELENNEL-QKQIIEDERDKIEQIKAELQKEAKDTEKQRQDI---ENDRRNNEEMV--- 2846
Query: 1424 LEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNA 1245
++Q+ K + ++ D I+ L+ Q L+ + KE ++
Sbjct: 2847 -IKLQNEKKD--------------IETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDL 2891
Query: 1244 KARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL 1065
K + LESQNR + +L +IQ+ER ++E LS + E+L+ E
Sbjct: 2892 KKTNTEMKDLEKQLESQNRQHEIQL-------AEIQKEREILEQLKLTLSKQKEDLEKE- 2943
Query: 1064 KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLR-NENAKLKNE 888
++ + E + L E L Q + E ++ + +DEL R N +L+N
Sbjct: 2944 RDCFEKEKADISLREELQEQS------EREGIGKTRVRIKKEMDELKQTRLNVVKELENN 2997
Query: 887 ALY-EYHDYERKNVSGSRAEAMSVL---------ISKSLGNGRANQREFQNKEED-SSGV 741
L + + ER + +AE I K N + QN+++D +
Sbjct: 2998 ELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETST 3057
Query: 740 DLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXI 561
D ++++ LE Q Q+L + E + + ++ ++ +++ L
Sbjct: 3058 DRIRDEEANLEVQKQRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQ 3117
Query: 560 RVRSLKKENTRLRSEMKGELTPSRS-FKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXX 384
+ R + ++ S+ K +L R F+ + ++ ++ + I
Sbjct: 3118 KEREILEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGID---------- 3167
Query: 383 XKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXX 204
+TRT QE+D L + + Q + +++ +++Q
Sbjct: 3168 ---NTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAEL--------- 3215
Query: 203 KWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKD 102
EK EL L E T+LKKD
Sbjct: 3216 ------KKEAEKTKLELQNERQNLEEAGTKLKKD 3243
Score = 89.7 bits (221), Expect = 5e-15
Identities = 126/682 (18%), Positives = 290/682 (42%), Gaps = 37/682 (5%)
Frame = -1
Query: 2282 EEEKQHTI-ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
E++K++T+ E+Q+ + + NE+I ++ + EQ ++ K E ++ ++ +
Sbjct: 5258 EKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQ-------MNQKQDELDQLKTEI 5310
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
QN Q +E+ + +R + + + L ++ + + ++R ++K +++E QK
Sbjct: 5311 QNLQQELEKEKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQK 5370
Query: 1925 ETVSKELALSVSREQKLASDLKALSEKE---ESTKNQLLIQTEQNK-QLELEIEKLYGSL 1758
+ + KE + L DLK + ++ E KN+L EQ K +LE E +++
Sbjct: 5371 QEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKL----EQMKIELEREADEIRKIK 5426
Query: 1757 QMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSAT 1578
+ Q E L+ E++ + + + + +QE + K + E +A ++ +
Sbjct: 5427 EETQNERQSLEKMTEELKKEKESFTHLAEDTKKEQEILDKVKVANESLMADLQKEKSNLE 5486
Query: 1577 DMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEE---------------------VLGNIN 1461
+M++ S V E L +D+++ L+ E ++ N+
Sbjct: 5487 EMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQQREIEKEKINIESERAAIIKNVE 5546
Query: 1460 SLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQD 1281
L++ + E ++ + E E+ Q L+ E D I+ I +E + Q +++
Sbjct: 5547 DLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEE 5606
Query: 1280 ESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNV 1101
+ + K+ + K++ L +NR ++ +K IQ +++++E E +
Sbjct: 5607 MTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIE-------KKIKSIQSDKDMLEKEKHD 5659
Query: 1100 LS---SEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDE 930
L SE+ +K +L++ K+ ++ L + E + ++ + EE++ + DE
Sbjct: 5660 LEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDE 5719
Query: 929 LICLRNENAKLKNEALYEYH-------DYERKNVSGSRAEAMSVLISKSLGNGRANQREF 771
L L+ E L+ E E +R+ + + I +++ N R ++
Sbjct: 5720 LDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNER--KQLD 5777
Query: 770 QNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLS-DMX 594
++KEE ++ + ++ + L E +M + + + ++ NKLE+M+ L +
Sbjct: 5778 KDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREAD 5837
Query: 593 XXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQ 414
+ + L+K L+ E K + K RE + + E+ + +E +Q
Sbjct: 5838 DIRKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTK-REKNSLDEMKVANESSMADLQ 5896
Query: 413 XXXXXXXXXXXKIDTRTSETQE 348
I +T + ++
Sbjct: 5897 KEKSNLEEMKENISKQTEDIEK 5918
Score = 89.0 bits (219), Expect = 8e-15
Identities = 124/608 (20%), Positives = 262/608 (43%), Gaps = 47/608 (7%)
Frame = -1
Query: 2303 KEVSRLYEE-EKQHTIELQENFNALRQKNEDICLKIEANNNLLEQK---DNIIVELSHKL 2136
KE+ R +E EK E + L ++ + + LL+ K D + E+ +
Sbjct: 887 KEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLFEMDSER 946
Query: 2135 QENEEQRSALQNDMQSVEQMH-----------AVSQTEREELNR---QLVLLRDDVNHLK 1998
+E E+ R ++N+ + +EQ A Q ++EEL + QLV+ + +N +
Sbjct: 947 KELEQMRFQVENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDTESMNRSR 1006
Query: 1997 EALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLL 1818
E +A DR E + +++ Q+E V+K L + RE+ L L+ E E ++
Sbjct: 1007 E---LARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRL-LRKDMENEREDLEKIR 1062
Query: 1817 IQT-----------EQNKQLELEIEKLYGSLQM-KQMENTLLKDGNEKIYDLCKLLATKS 1674
++T E+ ++ EIE+L+ + Q E + E++ + + +
Sbjct: 1063 VETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRKMEAMKREM 1122
Query: 1673 REVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVF 1494
E++ + + KQ NI+ ++ + ++ N LEM MK D+
Sbjct: 1123 GEIEDMKVELTKQKENIDMKMEHAR--------LEMTN----------LEM---MKADLL 1161
Query: 1493 SLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILI 1314
KE++ + + +++ Q QM+ ++E+ + E +++ +AE++ +QH+
Sbjct: 1162 RQKEDIENQMLAAKSERQ-------QMEVMRTEILKQKEDVERKMELAKAEMEKMQHVKD 1214
Query: 1313 ELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQE 1134
E++++ + L++ Q+ +E+ + + K L+ + + + + +IQ
Sbjct: 1215 EIQKQRKELEERMQKTKREIGEMELMKREMEGKKKELDQRMKLTMRKKEEMERLKMEIQR 1274
Query: 1133 ERNVVE---SEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRF 963
++ +E E E+E +K+E++ ++ E + LR+ E L + E +L I
Sbjct: 1275 AKDDMEFKRVETERQKYEMEQVKAEIQRAR--EEFELRVEERDLEEEKEQMNLTI----- 1327
Query: 962 AEEKLMRILDELICLRNENAKLKNE-------ALYEYHDYERKNVSGSRAEAMSVLISKS 804
+ ++ ++ R K K + + D E N R + + +
Sbjct: 1328 -----INLIQQIEATREMVHKTKFQFENRMAGSQMGTADQEEMNAEMQRL-ILEIEHIRE 1381
Query: 803 LGNGRANQREFQNKE---EDSSGVDLLKNKCTR----LEFQVQKLSEKAEMFETKSREAQ 645
+ G + E QNKE D + LLK + R +E++ +K+ + + E S+ Q
Sbjct: 1382 MLRGLKGEVE-QNKEIMKRDREEIRLLKIEVQRRRREIEYREEKIMREQDELELMSKMGQ 1440
Query: 644 QMANKLEE 621
+ +LEE
Sbjct: 1441 RQREELEE 1448
Score = 87.8 bits (216), Expect = 2e-14
Identities = 151/751 (20%), Positives = 299/751 (39%), Gaps = 65/751 (8%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQ--KNEDICLK--------IEANNNLLEQKDNIIV 2154
K++++ EE ++ E+++ + + Q K+ D LK IE N LEQ +
Sbjct: 4070 KQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMK---I 4126
Query: 2153 ELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVD 1974
EL + E + + QN+ Q +E+M EEL ++ KE+ + +
Sbjct: 4127 ELEKEADEIRKIKEETQNERQRLEKM-------TEELKKE-----------KESFTHLAE 4168
Query: 1973 DRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQ 1794
D +K L ++ E++ +L S +++ ++ +E E K ++ ++ ++ +Q
Sbjct: 4169 DTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQ 4228
Query: 1793 LELEIEKLYGSLQMKQMENTL--------LKDGNEKIYDLCKLLAT--KSREVQGQQEGI 1644
L+ EI K G ++M++ N +KD K++ L + L + RE + +
Sbjct: 4229 LQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREV 4288
Query: 1643 LKQ---DI-----NIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFS- 1491
LKQ D+ IE T+ + +M K++ ++E KD V +
Sbjct: 4289 LKQIKTDLKRKAEEIEKIKLETQHDRQRVEEMTAQIQKERDKINNLIEE-TNRKDMVLNE 4347
Query: 1490 LKEEVLGNINSLRNDAQMVQVALEQMQDTKSELF-AEAEIRAQEVLRL------------ 1350
+K E+ I ++ +D M++ ++ T+S+L A+ + Q ++L
Sbjct: 4348 IKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEK 4407
Query: 1349 -----QAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRS 1185
E+ I+H ++K+K QDE + E+ N + L + SQ
Sbjct: 4408 MNEKFTIEIHDIKHQEEQMKQK----QDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDL 4463
Query: 1184 LKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-KESKDLEGYFLRLFEILLG 1008
++EL Q I E + + E E K E+ KE D + L E L
Sbjct: 4464 RQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLKM 4523
Query: 1007 QHVEVASLDIESCRFAEEKL--------MRILDELICLRNENAKLKNEALYEYHDYERKN 852
++ L+ E + + K+ +R + E I +N + EAL E ER++
Sbjct: 4524 MKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKE----ERED 4579
Query: 851 VSGSRAEAMSVLISKSLGNG-------RANQREFQNKEEDSSGVDLLKNKCTRLEFQVQK 693
++ + VL + N R + +E S + ++NK L + +
Sbjct: 4580 LAEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDE 4639
Query: 692 LSE-KAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSE 516
L + +AE+ + + ++ N E + D+ SLK + +E
Sbjct: 4640 LRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENE 4699
Query: 515 MKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTL 336
K L ++ RE I++I + + D ++ +I+ ET D +
Sbjct: 4700 -KEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMV 4758
Query: 335 MDD-NRKYWNRVSHFTKQTQSLQNSVQELQQ 246
+++ NR ++ L+ +L++
Sbjct: 4759 LNEKNRDIEEKIKSIQSDKDMLEKEKHDLEK 4789
Score = 85.9 bits (211), Expect = 7e-14
Identities = 124/662 (18%), Positives = 287/662 (43%), Gaps = 38/662 (5%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIE----ANNNLLEQKDNIIVELSHKL 2136
+E ++++++ L E + E++ ++ E AN + + ++ +++EL +
Sbjct: 3234 EEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIELKKTV 3293
Query: 2135 QENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFME 1956
+ + L+N + + + V Q E + L LL+ ++ + + + E
Sbjct: 3294 TDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQLRLRE 3353
Query: 1955 KQLQDLE------------NQKETVSKELAL-----SVSREQKLASDLKALSEKE----E 1839
+L+ L+ N+K ++++ L + R Q+ + + + K+ E
Sbjct: 3354 VELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYASKDRANLE 3413
Query: 1838 STKNQLLIQTEQNKQLELEIEKLYGSLQMK-QMENTLLKDGNEKIYDLCKLLATKSREVQ 1662
K++++ Q Q+++E+ K G ++ + QM NT K+ ++K L + +E++
Sbjct: 3414 KEKSEMI---AQKHQMDIELNKERGLIEERTQMLNTYEKEMDQK----RTALEVEMKELK 3466
Query: 1661 GQQEGILKQDINIEDELARTK-EVGRSATDMKKVNS---DAGAKVSGILEMLLPMKDDVF 1494
++ I ++ +++L + K E+ R A D+KK+ + + + E L KDD+
Sbjct: 3467 YHKQAIQEE----KNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLA 3522
Query: 1493 SLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILI 1314
L E+ + R D +M + + D + E ++R + + + +D+ + +I
Sbjct: 3523 HLAED------TKRKDDEMKVLHESALADIQKEKCNLEQMR-ESMFKQNEMIDSEKKKMI 3575
Query: 1313 ELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKA-FQIQ 1137
+ K Q +Q E R E+ K+ + N + + +N+ L EL Q++ Q++
Sbjct: 3576 LREDKLQQMQAEINRQQTEMDTKKSIIEN---ERAAMTKKNQDLMTELTKQSEDVEIQMK 3632
Query: 1136 E---ERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCR 966
E E+ ++ES+ +L +VENL+ +L +++ E D E
Sbjct: 3633 EVLTEKELLESDRKLLKKDVENLQQKL---------------LIIESDSESLKQDRELLE 3677
Query: 965 FAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSR----AEAMSVLISKSLG 798
+E L ++ +L E K+K E +E E + + M+ I++ +
Sbjct: 3678 NEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIH 3737
Query: 797 NGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEM 618
+ + +++ + K+++ +D LK + L+ Q+L ++ E+ E ++L++
Sbjct: 3738 DIKYQEKQMKQKQDE---LDQLKTEIQNLQ---QELEKEKEIIMKDRSELDLKQSELDKQ 3791
Query: 617 QQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGD 438
Q ++D+ + ++K E +L + + R + + F + N D
Sbjct: 3792 QTNMNDI-------------IETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLD 3838
Query: 437 ED 432
ED
Sbjct: 3839 ED 3840
Score = 85.1 bits (209), Expect = 1e-13
Identities = 119/600 (19%), Positives = 256/600 (42%), Gaps = 34/600 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEE 2121
E+S++ EE + L++ NAL+++ E + +I+ N +L D I V NE
Sbjct: 6101 EISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVL---DKIKV-------ANES 6150
Query: 2120 QRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDD----RAFMEK 1953
+ LQ + + +E+M RE +++Q+ +D+ + KE + D+ + ++K
Sbjct: 6151 TLADLQKEKRILEEM-------RENISKQI----EDIENEKEKSKLREDELKKLQTEVQK 6199
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTE----QNKQLEL 1785
Q +++ +K + E A + +Q + ++LK SE E ++L + E L+
Sbjct: 6200 QQSEIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKK 6259
Query: 1784 EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 1605
++E L L + ++ LK E + + + ++Q Q + I K + E R
Sbjct: 6260 DVEDLQQKLMSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQR 6319
Query: 1604 TKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVA 1425
+E A++ E + + +++ ++ + + +R + + ++
Sbjct: 6320 VEE--------------KTAQIQKEREEINTLVEEIKKKRDIIDESYTEIRKEKEAIESD 6365
Query: 1424 LEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNA 1245
++ KS+ F + + + +Q + +A++ + E+ R L+DE KE+ A
Sbjct: 6366 RSDLEKAKSQTFKQNKNIEIALAEIQQKRNALEKMSKEISRDRMKLEDEK----KEIQLA 6421
Query: 1244 KARLNNV-------------MSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHN 1104
+ L + + I ES + +AE+ LQ + + + R S+ +
Sbjct: 6422 REELERMHGDMQRQQEAKDHLLSGITDESLLKKSEAEIVLQPSQVDKAKPARKTEISDSD 6481
Query: 1103 -----VLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRI 939
V +LK LK+ + E L + +L Q ++ E+KL I
Sbjct: 6482 KQPVFVQQMPEMDLKDALKKDFESEKLDLPKVKDVLPQDQQMK---------LEQKL--I 6530
Query: 938 LDELICLRNENAKLKNEA-LYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQR---EF 771
DE+ L+ A+L+ EA E + +N + + L + N R N+ +
Sbjct: 6531 EDEMDKLKQMRAELQKEADQIEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINIQK 6590
Query: 770 QNKEEDSSGVDLLKNKCTRLEFQV----QKLSEKAEMFETKSREAQQMANKLEEMQQTLS 603
N+++ ++ + K R++ ++ ++L+++ E + E Q+ LEEM+ +S
Sbjct: 6591 VNQQKQATAFQMEKTDFERIKTEIDQANKELADQQEKNKKTITEMQKERETLEEMRANIS 6650
Score = 85.1 bits (209), Expect = 1e-13
Identities = 120/621 (19%), Positives = 270/621 (43%), Gaps = 60/621 (9%)
Frame = -1
Query: 2279 EEKQH-TIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIV----ELSHKLQENEEQR 2115
++K+H T E ++ + ++ KI+ LE++ ++ L+ L+E + Q+
Sbjct: 9318 DKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQIEAENLNKVLEEIKRQQ 9377
Query: 2114 SALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLE 1935
L+ ++ M + REE R+ + + + + + A + +R ++KQ Q+L+
Sbjct: 9378 EKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQKQELQ 9437
Query: 1934 NQKETVSKELALSVSREQKLASDLKALSEKE---ESTKNQLLIQTEQNKQLELEIEKLYG 1764
Q + + + ++ + + ++L E++ E N++L Q + ++ + ++ K +
Sbjct: 9438 KQADDLDMRM---IAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWN 9494
Query: 1763 SLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRS 1584
L + Q E +++ N+ + ++ E+ G++ I K+ +E+ L + +
Sbjct: 9495 KLDVLQNE---MQNENKAMEEI-------KYELDGKRNEINKEQQRLEESL---RAINEE 9541
Query: 1583 ATDMKKVNSDAGAKVSGILEM----------LLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
D++ + +D + I EM L +K ++ K E+ L ND M+
Sbjct: 9542 KGDLEIMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMI 9601
Query: 1433 Q--------------VALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIEL---- 1308
+ +QM+D +SEL + + E +++ + ++ ++ E+
Sbjct: 9602 EKERNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQR 9661
Query: 1307 ---KRKNQTLQDESQRNAKE---LWNAKARLNNVMSKNINLE----SQNRSLK-AELHLQ 1161
K K + L E Q E L + L N + N+E ++ +LK E HLQ
Sbjct: 9662 NDFKLKKEELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQ 9721
Query: 1160 AQK--AFQIQEERNVVESEHNVLSSEVENLKSELKESKD-LEGYFLRLFEILLGQHVEVA 990
K I EE + + + +S+ + K ELK KD LE + +
Sbjct: 9722 RDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRID 9781
Query: 989 SLDIESCRFAEEKL---MRILDELICLRNENAK---LKNEALYEYHDYERKNVSGSRAEA 828
D + + EE L ++ +E CL N K +K +A E+H+ +K + +
Sbjct: 9782 EFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQK-IEELQTLQ 9840
Query: 827 MSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREA 648
++ K + + + ++ D +L++ K T ++ + +KL++ +M E + +
Sbjct: 9841 EQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREK-TEVDHEQKKLNDDIKMIEQEKEDL 9899
Query: 647 QQMANKL----EEMQQTLSDM 597
++M +++ +EM++ S++
Sbjct: 9900 EKMKSEIMTQKQEMEKERSEL 9920
Score = 85.1 bits (209), Expect = 1e-13
Identities = 116/634 (18%), Positives = 264/634 (41%), Gaps = 36/634 (5%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
K S + ++ +Q E E N +RQ + C IE + ++++ + E H++Q +
Sbjct: 11293 KMKSEIMKQRQQMEEERSELENKIRQTYIEKC-DIENSKEIVQKLMVEVEEQKHEIQFQK 11351
Query: 2123 EQ------------------RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLK 1998
E+ +S LQN+ + ++ ++ V + ERE L L + +K
Sbjct: 11352 EELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMK 11411
Query: 1997 EALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLL 1818
+ +EK + QK+ + + L +++ K L ++ + Q+
Sbjct: 11412 SITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVS 11471
Query: 1817 IQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILK 1638
Q E++ E E+++ SL+ + +K E +E + ++E +
Sbjct: 11472 KQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEP--------EEIKKEKEKEEE---E 11520
Query: 1637 QDINIEDELARTKEVGRSATDMKKVNSDAG---AKVSGILEMLLPMKDDVFSLKEEVLGN 1467
Q++ ++ E+ R KE+ + + +++V S+ K++ +M+ K+D+ +K E++
Sbjct: 11521 QEMRVKVEMER-KEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQ 11579
Query: 1466 INSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTL 1287
+ + + ++Q K ++ EI + ++ ++ + IQ EL + Q +
Sbjct: 11580 RQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKI 11639
Query: 1286 QDESQ---RNAKELWNAKARLNNVMSKNINLESQN-RSLKAELHLQAQKAFQIQEERNVV 1119
DE +N E N R+ M + I E + + ++ L + ++ + EE
Sbjct: 11640 ADEQDLLIQNKIEQQNENERIKE-MDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRR 11698
Query: 1118 ESEHNVLSSEVENLKSELKESKDL---EGYFLRLFEILLGQHVE--------VASLDIES 972
+ + +S+++ K +L +DL E + L Q ++ + + +E
Sbjct: 11699 KEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEE 11758
Query: 971 CRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNG 792
+EKL + + E + E + + E D ++N E M L+ K +
Sbjct: 11759 KTEMDEKLQQAIKEYESIIEETNRKRTELEEIEVDQSQQN---KNVETMKDLLEKERKDT 11815
Query: 791 RANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQ 612
+ E Q K+ D + ++++ + E + L E+ ++ E K+ E + + LE+ ++
Sbjct: 11816 EKEREELQ-KQADDLEMQMIEHG-DKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKE 11873
Query: 611 TLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK 510
DM +++ K E ++ E++
Sbjct: 11874 ---DMMKKWNELDGLQKEIQNQKNEMEEIKCELE 11904
Score = 84.3 bits (207), Expect = 2e-13
Identities = 147/702 (20%), Positives = 294/702 (41%), Gaps = 78/702 (11%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQEN---FNALRQKNEDICLKIEANNNLLE------QKDNIIVE 2151
+EV +E +Q T +L+E+ F+ ++KN I +I+ ++ LE K+ I E
Sbjct: 2208 QEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTIFE 2267
Query: 2150 LSHK---LQENE-----EQRSALQNDMQ----SVEQMHAVSQTER--------------- 2052
L + L+ENE +Q LQN ++ VEQM A +R
Sbjct: 2268 LEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTARGRETT 2327
Query: 2051 --EELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQK 1878
EE +++ LR++ ++++ + + E +++ LE + E + K+ + +E +
Sbjct: 2328 ALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAM-KKYKEKLDKEYE 2386
Query: 1877 LASDLKALSEKE-ESTKNQLLIQTE--QNKQLELEIEK--LYGSLQMKQMENTLL-KDGN 1716
+ L EKE + + +L I+ E + K+ ELEI+K +Y M + + ++ K
Sbjct: 2387 DLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKT 2446
Query: 1715 EKIYDLCKLLATKSREVQGQQEGILKQDINI-EDELARTKEVGRSATDMKKVN---SDAG 1548
+++ ++ K + EV+ Q+ +++ ++ I ++E KE R + N S
Sbjct: 2447 DELDEVRKKINADLSEVEKQKSALVQMNLKISQEESYVKKEKDRLKLQENEQNMQMSQLN 2506
Query: 1547 AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRA 1368
AK + + E M+ L E V+ + + + + + +MQ+ A ++
Sbjct: 2507 AKQNELDERQAEMEKQKREL-ENVMDRLEKEKVEITKEKQRVNEMQNEVKRKNASVDLIK 2565
Query: 1367 QEVLRLQAEVDAIQHI----LIELKRKN-------QTLQDESQRNAKELWNAKARLNNVM 1221
QEVLR Q ++ + I L ++K K + L D+ + KE+ +
Sbjct: 2566 QEVLREQDHIENSREILNRELEKIKEKKTILAEEFEALDDKKEMIGKEMQRLGKMKAELQ 2625
Query: 1220 SKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-------- 1065
+ + E Q R + + + ++Q E+ +E+ + + E NL+ +
Sbjct: 2626 KEAEDTEKQRRDIDNDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLESDRD 2685
Query: 1064 ---KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLK 894
KE DLE + + L + +E S E +K IL++ L+ +K K
Sbjct: 2686 TLEKERFDLEKTKTEMKD--LEKQLESQSRQHEIQLVEIQKEREILEQ---LKINLSKQK 2740
Query: 893 NEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEE-DSSGVDLLKNKCT 717
+ E +E++ S E + K G + R Q +E + + ++++K +
Sbjct: 2741 EDLEKERDCFEKEKADISLREELEEQSEKE-GIDKTRVRIKQEMDELEQTRLNVVK-ELE 2798
Query: 716 RLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTL-SDMXXXXXXXXXXXIRVRSLKK 540
E Q Q + ++ + E E Q+ A E+ +Q + +D + ++
Sbjct: 2799 NNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIET 2858
Query: 539 ENTRLRSE------MKGELTPSRSFKHREGSFIKEINIGDED 432
R+R E +K L R +E +K+ N +D
Sbjct: 2859 STDRIRDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEMKD 2900
Score = 84.3 bits (207), Expect = 2e-13
Identities = 158/788 (20%), Positives = 326/788 (41%), Gaps = 59/788 (7%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNII----VELSHKLQENEEQR 2115
EE+KQ + ++N + R+ ++ K++ + E++ N + +EL + E + +
Sbjct: 4911 EEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIK 4970
Query: 2114 SALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLE 1935
QN Q +E+M EEL R+ KE+L+ +D +K L +++
Sbjct: 4971 EETQNKRQRLEKM-------TEELIRE-----------KESLAHLAEDTKTEKKILDEMK 5012
Query: 1934 NQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQ 1755
E+ +L S +++ ++ L E ++ K + ++ ++ K+L+ E++K +
Sbjct: 5013 VANESSMADLQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKID 5072
Query: 1754 MKQ--MENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSA 1581
M++ +E+ EK ++ L KS +V+ Q + IL E EL
Sbjct: 5073 MEKTNIESERAAMIREK-QNMMTELKKKSEDVEIQMKEIL-----TEKELLH-------- 5118
Query: 1580 TDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQM---VQVALEQMQ 1410
D K + D V + + L+ ++ D LK + N QM +Q+ ++++
Sbjct: 5119 NDRKLLTRD----VENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEIE 5174
Query: 1409 DTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLN 1230
K E + + + ++Q E D I +++ E RK+ L ++++ +++ + ++ +
Sbjct: 5175 KIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKD 5234
Query: 1229 NVMSKNINLESQNRSL-KAELHLQAQK---AFQIQEERNVVE------------------ 1116
+ + NLE L K + L+ QK +IQ+ER VE
Sbjct: 5235 MLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEE 5294
Query: 1115 ------SEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAE- 957
E + L +E++NL+ EL++ K++ F++ + LD + +
Sbjct: 5295 QMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQFDL------RQSELDKQQTNMNDI 5348
Query: 956 -EKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQ 780
E + +L + E + K E E HD+++ S + + + + K + N+
Sbjct: 5349 METMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDK-DLKMMKLQKQVFEEEKNK 5407
Query: 779 REFQNKEEDSSGVDLLK------NKCTRLEFQVQKLSEKAEMF---ETKSREAQQMANKL 627
E E + ++ K N+ LE ++L ++ E F +++ Q++ +K+
Sbjct: 5408 LEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFTHLAEDTKKEQEILDKV 5467
Query: 626 E--------EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHRE 471
+ ++Q+ S++ V + KKEN RLR + +L + RE
Sbjct: 5468 KVANESLMADLQKEKSNLEEMRENISKQTEDVEN-KKENLRLREDELWQLQAEIYKQQRE 5526
Query: 470 GSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFT 291
I++ I E + I +D R SE+ ++D R+ +
Sbjct: 5527 ---IEKEKINIESERAAIIKNVEDLQHKIISLD-RDSESLKLD------REAFENEREVL 5576
Query: 290 KQTQS-LQNSVQELQQXXXXXXXXXXXXXXKWGGI--DMNSIEKQLKELNIHVMQLVEHN 120
KQ ++ L+ E+++ I D + I ++E N M L E N
Sbjct: 5577 KQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKN 5636
Query: 119 TRLKKDVK 96
++K +K
Sbjct: 5637 RDIEKKIK 5644
Score = 84.0 bits (206), Expect = 3e-13
Identities = 140/786 (17%), Positives = 327/786 (41%), Gaps = 26/786 (3%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQ-----ENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHK 2139
+E + EE K IE++ E ++K E+ ++ + E+ D I +L
Sbjct: 10930 EEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKK-EELDQIKSQLERV 10988
Query: 2138 LQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFM 1959
E + ++ L +D + +EQ + + E+ +Q + ++ + L + +R
Sbjct: 10989 RSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLER--- 11045
Query: 1958 EKQLQDLENQKETVSKELA--------LSVSREQKLASDLKALSEKEESTKNQLLIQTEQ 1803
D+EN KE V K + + + +E+ K E+ +N+ +Q E
Sbjct: 11046 ----HDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNEN 11101
Query: 1802 NKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQD--- 1632
+ E++ E +K+ME L K+ E + + + +++ + KQ+
Sbjct: 11102 ERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDL 11161
Query: 1631 INIEDELARTK-EVGRSATDMKKVNSDAGAKVSGILEMLL----PMKDDVFSLKEEVLGN 1467
+N D L + + E+ T +++ + A+VS E L M+++ SL+E +
Sbjct: 11162 MNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKI-K 11220
Query: 1466 INSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTL 1287
I ++ + ++ E+ ++ + + A+ E++ +E+ +++++++ ++ E+ + + L
Sbjct: 11221 IIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRS---EIDHEQKKL 11277
Query: 1286 QDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEH 1107
D+ + +E + + + +M + +E + L+ ++ + I+ + +V+
Sbjct: 11278 NDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQK-- 11335
Query: 1106 NVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL 927
L EVE K E++ K+ LDIE + A+E+ + I ++
Sbjct: 11336 --LMVEVEEQKHEIQFQKE--------------------ELDIERQKIADEQDLLIQNKS 11373
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSS 747
L+NEN ++KN + E ER+ + + M + K ++ E + ++ED
Sbjct: 11374 E-LQNENERIKN--INEVIKKERETL-----KEMEAYLEKEKEEMKSITEETRRQKED-- 11423
Query: 746 GVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXX 567
L+ T + Q Q L + ++ E +E +++ +K +++QQ + +
Sbjct: 11424 ----LEKMSTHINEQKQDLRSQRDLLE---QEREEINHKWKQLQQRIDEFDAQVSKQKEE 11476
Query: 566 XIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXX 387
+ KE+ + E K + ++ E IK+ +E++ Q
Sbjct: 11477 DLPKEKEMKEDRKSLEETKANILEMKT--KAEPEEIKKEKEKEEEE----QEMRVKVEME 11530
Query: 386 XXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQ-TQSLQNSVQELQQXXXXXXXXXXXX 210
+I+ S+ + + + MD +K N +Q + L+ E+ +
Sbjct: 11531 RKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMK------------ 11578
Query: 209 XXKWGGIDMNSIEKQLKELNIHVMQ--LVEHNTRLKKDV--KFGFAWANSMHDLNGQEQK 42
+E++ EL+ + Q L +H+ K++ K H++ Q+++
Sbjct: 11579 -------QRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEE 11631
Query: 41 LKVDEE 24
L ++ +
Sbjct: 11632 LDIERQ 11637
Score = 83.6 bits (205), Expect = 4e-13
Identities = 153/813 (18%), Positives = 320/813 (39%), Gaps = 62/813 (7%)
Frame = -1
Query: 2276 EKQHTI---ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
EKQ I E+Q+ L + NE ++I + EQ + K E ++ ++ +
Sbjct: 4388 EKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQ-------MKQKQDELDQLKTEI 4440
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
QN Q +E+ + +R +L+ + L ++ + + ++R ++K ++ E QK
Sbjct: 4441 QNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQK 4500
Query: 1925 ETVSKELALSVSREQKLASDLKALS------EKEESTKNQLLIQTEQN----KQLELEI- 1779
+ + KE + L DLK + E E+S Q+ I+ E+ ++++ EI
Sbjct: 4501 QEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQ 4560
Query: 1778 ------EKLYGSLQMKQMENTLLKDGNEKIYD---------LCKLLATKSREVQGQQEGI 1644
EK+ +L+ ++ + N ++ D L +L KS ++ +E I
Sbjct: 4561 NERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKS-NLEEMRENI 4619
Query: 1643 LKQDINIEDE----LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEV 1476
KQ ++E++ R E+ + ++ K + + I + DV L+ ++
Sbjct: 4620 SKQTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKI 4679
Query: 1475 LGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKN 1296
+ L DA+ +++ E ++ E E+ Q L+ E D I+ I +E +
Sbjct: 4680 I----CLDRDAESLKLDREAFEN-------EKEVLKQMKTELEREADEIEKIKLETQHDR 4728
Query: 1295 QTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVE 1116
Q +++ + + K+ + K++ L +NR ++ +K IQ +++++E
Sbjct: 4729 QRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIE-------EKIKSIQSDKDMLE 4781
Query: 1115 SEHNVLS---SEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLM 945
E + L SE+ +K +L++ K+ ++ L + E + ++ + EE++
Sbjct: 4782 KEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMN 4841
Query: 944 RILDELICLRNENAKLKNEALYE----YHDYERKNVSGSRAEAMSVLISKSLGNGRANQR 777
+ DEL L+ E L+ E E D + ++ S + ++ + + ++
Sbjct: 4842 QKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERK 4901
Query: 776 EF--------QNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLE- 624
+ + K+E D + L+ +K+ + +MFE + + +QM +LE
Sbjct: 4902 QLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELER 4961
Query: 623 -------------EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSF 483
+Q L M + K ++ EMK S +
Sbjct: 4962 EADEISKIKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMAD 5021
Query: 482 KHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRV 303
RE S ++E+ I ++ +E Q+ + +D + N
Sbjct: 5022 LQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKT--NIE 5079
Query: 302 SHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEH 123
S + QN + EL++ +E Q+KE+ L
Sbjct: 5080 SERAAMIREKQNMMTELKK-------------------KSEDVEIQMKEILTEKELLHND 5120
Query: 122 NTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEE 24
L +DV+ + DL ++LK+D E
Sbjct: 5121 RKLLTRDVE---NLQQKLIDLERDSKRLKLDRE 5150
Score = 83.6 bits (205), Expect = 4e-13
Identities = 128/620 (20%), Positives = 275/620 (44%), Gaps = 63/620 (10%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLE-QKDNIIVELSHKLQEN 2127
+E S L ++ KQ +E + N+ ++ E + +++E + ++ QK+ + +E E
Sbjct: 11585 EERSELDKKIKQTDLEKHDIENS-KEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQ 11643
Query: 2126 E---EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFME 1956
+ + + QN+ + +++M + ERE L V L+ + ++ + + +E
Sbjct: 11644 DLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLE 11703
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSEK--EESTKNQLLI------QTEQN 1800
K D+ QK+ + + L +++ L L ++ E T + +L+ +TE +
Sbjct: 11704 KMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMD 11763
Query: 1799 KQLELEIEKLYGSLQMKQMENTLLKD-------GNEKIYDLCKLLATKSREVQGQQEGIL 1641
++L+ I++ ++ + T L++ N+ + + LL + ++ + ++E +
Sbjct: 11764 EKLQQAIKEYESIIEETNRKRTELEEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQ 11823
Query: 1640 KQDINIEDELAR---TKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLG 1470
KQ ++E ++ +E+ + + D +K + A +L +DD+ KE+++
Sbjct: 11824 KQADDLEMQMIEHGDKEEMSKRSLDEEKKLLEQKANE------ILRQRDDLEKEKEDMMK 11877
Query: 1469 NINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAI------------- 1329
N L + +Q +M++ K EL + +E RL+ ++ +
Sbjct: 11878 KWNELDGLQKEIQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLEIVRVD 11937
Query: 1328 ----QHILIELKRKNQTLQDE-SQRNAKELWNAKARLNNVMSKNI------NLESQNRSL 1182
Q + E++ K + +DE Q AK L + K N SK++ +E +L
Sbjct: 11938 YEKHQQQIEEMRVKTKMERDELDQLMAKMLMDRK---ENERSKDMIGLLKKEMEQTKFNL 11994
Query: 1181 KA---ELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILL 1011
A EL L+ QK +++ + ++E +SEV+ LK + E KD + + E L
Sbjct: 11995 DAQEEELKLEKQKIQNEKKDLEMFKAEIKREASEVKTLKEQQLE-KDTKAFEALKEEHLP 12053
Query: 1010 GQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKL-KNEALYEYHDYERKNVSGSR- 837
GQ V+ + E + E K RIL E + E +L +N+ + E+ + +
Sbjct: 12054 GQFVQQKGGEFERIQIDEVK--RILSE---IHKEKKELERNKQILEHQREALLEIKSKQP 12108
Query: 836 AEAMSVLISKS---------LGNGRANQREFQNKEEDSSGVDLLKNKCTRL---EFQVQK 693
+E + V++ S + + A+Q E K D++K T + E+++ K
Sbjct: 12109 SERLDVILVSSATQTSDLEDIPDVSASQGETVEKH-----TDIIKEYTTSIPKEEYEIDK 12163
Query: 692 LSEKAEMFETKSREAQQMAN 633
L ++ + +RE +MA+
Sbjct: 12164 LKQQGDKKLKSTREDTKMAD 12183
Score = 83.6 bits (205), Expect = 4e-13
Identities = 137/665 (20%), Positives = 282/665 (42%), Gaps = 98/665 (14%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNI---IVELSHKLQE 2130
E+ +L ++ ++ EL++ L+++ + KI+A Q D I I L + +E
Sbjct: 12537 EIQKLRKQYEKEKCELEQIKPDLQKREPE---KIDAE----VQHDEIHGGIDSLKEEREE 12589
Query: 2129 NEEQRSALQNDMQSVEQMHAVSQTEREELNR------QLVL----------LRDDVNHLK 1998
E+ ++ LQN ++ E M + + E++EL + Q+ + L+D++ ++
Sbjct: 12590 IEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIE 12649
Query: 1997 EALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKA-----LSEKEEST 1833
L + + ++E+ ++L +K + + + +L +K +S+ EE
Sbjct: 12650 AILKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKMEERE 12709
Query: 1832 KNQLLIQ------TEQNKQLELEIEKLYG-SLQMKQMENTLLKDGNEKIYDLCKLLATKS 1674
+ I+ E++++++ E E+L ++K+ L + NE + K
Sbjct: 12710 AERKTIERVMDEMAEEHEKIKKEREELVNMEEEIKKQRRVLEESMNE--------MTKKK 12761
Query: 1673 REVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGIL----EMLLPMK 1506
E+Q ++ + KQ +ED +A S D+ S + IL E + MK
Sbjct: 12762 SELQHERSELYKQKQQLEDMIA-----SESKRDVDTERSRQDKEDEQILKREREEIADMK 12816
Query: 1505 DDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSE--------LFAEAEIRA------ 1368
D + KE+V + + + ++ Q+ D K E L+ + EI+
Sbjct: 12817 DQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEIQVKTNALE 12876
Query: 1367 ---QEVLRLQAEVDA--IQH---------ILIELKRKNQTLQDESQRNAKELWNAKARL- 1233
Q++ + + V+A IQH ++ E KRK + + E QR +++ + K RL
Sbjct: 12877 KMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFEDIESVKVRLV 12936
Query: 1232 ---NNVMSKNINLESQNRSLKAELHLQAQKAF-----QIQEERNVVESEHNVLSSEVENL 1077
N + N L++++ L+ L + QK F ++Q ER +E + L + L
Sbjct: 12937 TESNQIDKMNSELKTRSEELE-NLIKKQQKEFETKENEMQRERKALEKMNAELERKSTEL 12995
Query: 1076 KSELKE----SKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEK---------LMRIL 936
K+++++ DL+ + E+ E + L E + ++K + +
Sbjct: 12996 KNKIEKVTVWEADLQKEKNKTEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEM 13055
Query: 935 DELICLRNENAKLKNEAL----YEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQ 768
+ L CLRNE K L E H+ ++ ++E S+ K ++ E +
Sbjct: 13056 ENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTE-IQSEKESIEEEKKTLKQLKDENESK 13114
Query: 767 NKEEDSSGVDLLKNKCTRLEFQVQK---------LSEKAEMFETKSREAQQMANKLEEMQ 615
+ D++ + K +L Q +K L KAE + + R+A Q+ +++ +
Sbjct: 13115 RTQLDNT---IEKMNMDKLSIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDA 13171
Query: 614 QTLSD 600
+ L D
Sbjct: 13172 KILDD 13176
Score = 79.7 bits (195), Expect = 5e-12
Identities = 114/611 (18%), Positives = 267/611 (43%), Gaps = 43/611 (7%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
K S L + +Q E E +++ N + KIE N ++E+ + E + + +
Sbjct: 9610 KMKSELMTQRQQMEDERSELDQKIKEANTEKD-KIEKNKEIVERLMAEVEEQRNDFKLKK 9668
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNH----LKEALSMAVDDRAFME 1956
E+ + + ++ + + A +TE + + Q+ + + V + LKE + D+ ++
Sbjct: 9669 EELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIK 9728
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQ-----NKQL 1791
+++ QKE + K ++ ++ +++ + K E+E N Q +Q + Q+
Sbjct: 9729 SIIEETSRQKEDLEK-ISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQV 9787
Query: 1790 ELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKL-------LATKSREVQGQQEGILKQD 1632
+ E+ + + + E L++ N KI ++ + K E+Q QE I+K+
Sbjct: 9788 RKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEK 9847
Query: 1631 INIEDELARTKEVGRSATDMKKVNSD----------AGAKVSGILEMLLPMKDDVFSLKE 1482
E A T ++ D+ ++ S+ K++ ++M+ K+D+ +K
Sbjct: 9848 EKAE---AMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKS 9904
Query: 1481 EVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKR 1302
E++ + + + ++Q K ++ EI + + ++ + IQ EL
Sbjct: 9905 EIMTQKQEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDI 9964
Query: 1301 KNQTLQDESQ---RNAKELWNAKARLNNVMSKNINLESQNRSLK-AELHLQAQKAFQIQE 1134
+ Q + DE +N EL N R+ N+ N ++ + +LK E HL+ +K E
Sbjct: 9965 ERQKIADEQDLLIQNKSELQNENERIRNI---NEVIKKERETLKEMEAHLEKEK-----E 10016
Query: 1133 ERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEE 954
E + E ++E + +++KE + L+ Q ++ + E
Sbjct: 10017 EMKSITEETRRQKEDLEKMSTDIKEQN----------QDLMKQR-DLLEQEKEDINHEWT 10065
Query: 953 KLMRILDELICLRNENAKLKNEALYEYHDY--ERKNVSGSRAEAMSVLISKSLGNGRANQ 780
+L + +DE + +K K E L + + ERK++ ++A + + L + + +
Sbjct: 10066 QLQQRIDEFDA---QVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEK 10122
Query: 779 REFQNKEE-------DSSGVDLLKNKCTR----LEFQVQKLSEKAEMFETKSREAQQMAN 633
+ + +EE D +D +K++ R ++ + +KL++ ++ E + + ++M +
Sbjct: 10123 EKEEEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKS 10182
Query: 632 KLEEMQQTLSD 600
++ + +Q + +
Sbjct: 10183 EIMKQRQQMEE 10193
Score = 79.7 bits (195), Expect = 5e-12
Identities = 106/593 (17%), Positives = 267/593 (45%), Gaps = 25/593 (4%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLE-QKDNIIVELSHKLQEN 2127
+E S L + KQ IE + N+ ++ + + +++E + ++ QK+ + +E E
Sbjct: 10193 EERSELENKIKQTYIEKCDIENS-KEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQ 10251
Query: 2126 E---EQRSALQNDMQSVEQMHAVSQTERE---ELNRQLVLLRDDVNHLKEALSMAVDDRA 1965
+ + +S LQN+ + + ++ + + ERE E+ L ++++ + E +D
Sbjct: 10252 DLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRLKED-- 10309
Query: 1964 FMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLEL 1785
+EK D+ Q + + + L +++ K L ++ + Q+ Q EQ+ E
Sbjct: 10310 -LEKMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEK 10368
Query: 1784 EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 1605
+++ SL+ + +K E K +E + ++E +++I + E R
Sbjct: 10369 GMKEDRKSLEETKANVIEMKTKAEPEE------IKKEKEKENEEEEEEEEEIRVIVETER 10422
Query: 1604 TKEVGRSATDMKKVNSDAG---AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
KE+ + +++++V S+ K++ ++M+ K+D+ +K E++ + + +
Sbjct: 10423 -KELYQIKSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSEL 10481
Query: 1433 QVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQ---RNA 1263
++Q K ++ EI + ++ ++ + IQ EL + Q + DE +N
Sbjct: 10482 DNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQNK 10541
Query: 1262 KELWNAKARLNNVMSKNINLESQNRSLK-AELHLQAQKAFQIQEERNVVESEHNVLSSEV 1086
+L N R+ V + ++ + +L+ E+HL+ +K +E R+++E E ++
Sbjct: 10542 AKLQNENERIKKV---DEEIKKERETLREMEIHLKKEK----EELRSIIE-ETQRRKEDL 10593
Query: 1085 ENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNEN 906
E + +++ E K + L ++ + E +L + +DE +
Sbjct: 10594 EKMSTDINEQK-----------LHLKNQRDLLEQEREEINHEMTQLQQRIDEFDA---QV 10639
Query: 905 AKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDL--- 735
+K + + + + ERK++ ++A + + L ++E +++EE V++
Sbjct: 10640 SKQREDLTKQEMEEERKSLEETKARIIEMKTKAEL-QEIMQEKEEEDEEEMRVIVEMERE 10698
Query: 734 --------LKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSD 600
LK + ++ + +KL++ ++ E + + ++M +++ +Q + +
Sbjct: 10699 ELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEE 10751
Score = 79.3 bits (194), Expect = 7e-12
Identities = 138/744 (18%), Positives = 296/744 (39%), Gaps = 65/744 (8%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNII----VELSHKLQENEEQR 2115
EE+K+ + + +F+ R ++ ++ + E++ N + +EL + E + +
Sbjct: 3817 EEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIK 3876
Query: 2114 SALQNDMQSVEQM------------HAVSQTER--------------------------E 2049
+QN+ QS+E+M H T++ E
Sbjct: 3877 EEIQNERQSLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEKSNFE 3936
Query: 2048 ELNRQLVLLRDDVNHLKEALSMAVDD----RAFMEKQLQDLENQKETVSKELALSVSREQ 1881
E+ + +DV + KE L + D+ +A + KQ +++E +K + E A + +
Sbjct: 3937 EMRENISKQTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVE 3996
Query: 1880 KLASDLKALSEKEESTK-------NQLLIQTEQNKQLEL---EIEKLYGSLQ-MKQMENT 1734
L + +L ES K N+ + + +LE EIEK+ Q +Q
Sbjct: 3997 DLQHKIISLDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHERQRVEE 4056
Query: 1733 LLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSD 1554
+ D E + + K L E+Q Q++ + K+ +++ + + K+V +
Sbjct: 4057 MTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEE 4116
Query: 1553 AGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEI 1374
K+ + L D++ +KEE +N+ Q ++ E+++ K AE
Sbjct: 4117 EKNKLEQMKIELEKEADEIRKIKEET-------QNERQRLEKMTEELKKEKESFTHLAED 4169
Query: 1373 RAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQ 1194
E L A + ++ +L+++ L++ + +K+ +++ + + LE
Sbjct: 4170 TKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELE-- 4227
Query: 1193 NRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEIL 1014
L+AE+H Q +I+ E++ ESE + +V++L+ ++
Sbjct: 4228 --QLQAEIHKQQG---EIKMEKSNNESERAAIIKDVKDLQHKM---------------FS 4267
Query: 1013 LGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRA 834
L + +E LD E+ E L +I +L E K+K E HD + R
Sbjct: 4268 LDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIKLET---QHDRQ-------RV 4317
Query: 833 EAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKC-TRLEFQVQKLSEKAEMFETKS 657
E M+ I K + + N E+++ D++ N+ T ++ +++ + +M E +
Sbjct: 4318 EEMTAQIQK-------ERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEK 4370
Query: 656 REAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKH 477
+ ++ +KL ++ L I++ ++KE L + KH
Sbjct: 4371 HDLEKTRSKLLRAKENLEKQ---------RKIKLAEIQKEREDLEKMNEKFTIEIHDIKH 4421
Query: 476 REGSFIKEINIGDEDDTPL------IQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKY 315
+E ++ + D+ T + ++ ++D R SE + T ++D +
Sbjct: 4422 QEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMET 4481
Query: 314 W-NRVSHFTKQTQSLQNSVQELQQ 246
N K + + QE+++
Sbjct: 4482 MKNERKQLDKDKEETEEQKQEMEK 4505
Score = 77.4 bits (189), Expect = 3e-11
Identities = 122/621 (19%), Positives = 274/621 (44%), Gaps = 65/621 (10%)
Frame = -1
Query: 2273 KQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQ-ENEEQRSALQND 2097
KQ EL++ L ++ E+ E ++E + + I ++ +L+ E E+ + LQN+
Sbjct: 3174 KQEMDELEKTRQNLAKEQENN----ELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNE 3229
Query: 2096 MQSVEQMHAVSQTER-------EELNRQLVLLRD-----DVNHLKEALSMAVDDRAFME- 1956
Q++E+ + +R EEL R+ V+L + ++ + + +R +E
Sbjct: 3230 RQNLEEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIEL 3289
Query: 1955 -KQLQDLENQKETVSKELALSVSREQKLASDLKALSE-----KEESTKNQLLI--QTEQN 1800
K + D+ KE + +L + + ++++A + K+ ++ Q+ I +TEQ
Sbjct: 3290 KKTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQL 3349
Query: 1799 KQLELEIEKLYGSLQMKQMENTLLKDGNEK--IYDLCKLLATKS------REVQGQQEGI 1644
+ E+E+E+L + +Q E + N K I + +L K+ REV E
Sbjct: 3350 RLREVELEQLQALIYRQQDE----IEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYA 3405
Query: 1643 LKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNI 1464
K N+E E +++ + + ++N + G + +ML + ++ + + +
Sbjct: 3406 SKDRANLEKE--KSEMIAQKHQMDIELNKERGL-IEERTQMLNTYEKEMDQKRTALEVEM 3462
Query: 1463 NSLRNDAQMVQVALEQMQDTKSELFAEAE--IRAQEVLR------------LQAEVDAIQ 1326
L+ Q +Q ++Q K EL EA+ + +E R L+ E D +
Sbjct: 3463 KELKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLA 3522
Query: 1325 HILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAF 1146
H+ + KRK+ ++ + ++ K L + S K ++ L+ K
Sbjct: 3523 HLAEDTKRKDDEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQ 3582
Query: 1145 QIQEE-----------RNVVESEHNVLSSEVENLKSEL-KESKDLEGYFLRLFEILLGQH 1002
Q+Q E ++++E+E ++ + ++L +EL K+S+D+E +++ E+L +
Sbjct: 3583 QMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVE---IQMKEVLTEKE 3639
Query: 1001 V-----EVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSR 837
+ ++ D+E+ ++KL+ I + L+ + L+NE E + ++ G
Sbjct: 3640 LLESDRKLLKKDVEN---LQQKLLIIESDSESLKQDRELLENEK--EVLKQMKTDLQGEA 3694
Query: 836 AEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTR----LEFQVQKLSEKAEMF 669
E + + R + Q ++D + + + TR +++Q +++ +K +
Sbjct: 3695 EEIEKIKLETQHERQRVEEMTAQ-IQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDEL 3753
Query: 668 ETKSREAQQMANKLEEMQQTL 606
+ E Q + +LE+ ++ +
Sbjct: 3754 DQLKTEIQNLQQELEKEKEII 3774
Score = 77.0 bits (188), Expect = 3e-11
Identities = 132/656 (20%), Positives = 271/656 (41%), Gaps = 38/656 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQ-HTIELQENFNALRQKNEDIC-LKIEANNNLLEQK--DNIIVELSHKLQ 2133
E S++ +EK+ E+Q + Q E++ LK E N ++ + + EL K Q
Sbjct: 8221 EESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQ 8280
Query: 2132 ENEEQRSALQNDMQSVEQMHAVSQTERE--ELNRQLVLLR---------DDVNHLKEALS 1986
E E R LQ + + +EQ+ E+E E++R+LV DV KE L
Sbjct: 8281 EEESMREILQKEKEELEQLKKDINREKEDIEISRELVESEIYEGEVKGFTDVQKYKEELQ 8340
Query: 1985 MAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALS---EKEESTKNQLLI 1815
+ ++ ++ L+ L + + + + L + K ++L+ ++ +K E +
Sbjct: 8341 IVTEELLTKKRNLEQLNSDVQHLMQTLEEVDIQYIKKKAELEHITSEIQKREQILEKQKK 8400
Query: 1814 QTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKL-----------LATKSRE 1668
+ E+N + EIE + +L+ ME ++ EK + + L + E
Sbjct: 8401 KLEENGWIIEEIEMMKVTLESINMEILQKREDMEKEKENLRREKQETELFRGELQRQRDE 8460
Query: 1667 VQGQQEGI--------LKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLP 1512
V+ ++ + LK D + A ++ + +M+ + AK++ L
Sbjct: 8461 VESSRQALIMEKDQFKLKIDHQRNEMSAAFEKEHKRLENMENDLENQRAKLAESLNDAAK 8520
Query: 1511 MKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDA 1332
M+ + +K E+ + QMV+ +++ K E+ + + +LQ + +
Sbjct: 8521 MEQKLQQMKNELNKEKEQVEEMKQMVKTERVKIEQEKEEMRKQTQEIEDGHEKLQKKTEI 8580
Query: 1331 IQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSL-KAELHLQAQ 1155
+L + ++ L+D S + + + ++ N +E++ RSL + LQ
Sbjct: 8581 ADKLLQDANSESDRLKDLSMK-------LQMQRQDIEKTNTEMETKKRSLDRMSRELQDD 8633
Query: 1154 KAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIE 975
K +++ +R+ E + L + E L ++E++DLE L+ E E+A DIE
Sbjct: 8634 K-IRLKNDRDAYEKDMTHLELKREEL---VRETEDLERKILQQRE-----QDEMAKRDIE 8684
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGN 795
+ A E +M++ +++ RNE AK E +NV R + + + +
Sbjct: 8685 NQTEALE-VMKV--DILKKRNEFAK------------EMENVHSERQKLLLLQGALQSQE 8729
Query: 794 GRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQ 615
R F +++ +C + + AEM ET + E + +EE+Q
Sbjct: 8730 SELENRVFMEEQKHLKQAKAETEECRK---------QLAEMSETVTTEQNEYRKLIEELQ 8780
Query: 614 QTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEIN 447
+ + ++ KK+ ++S ++ +L S +H + + E N
Sbjct: 8781 REKEQL-------EISKNQIEQEKKDLQNMKSNLERQL---ESLRHEKANVEDEKN 8826
Score = 76.3 bits (186), Expect = 6e-11
Identities = 85/437 (19%), Positives = 201/437 (45%), Gaps = 27/437 (6%)
Frame = -1
Query: 2279 EEKQHTIELQENFNALRQKN-EDICLKIEANNNLLEQKDNIIVELSHKL-----QENEEQ 2118
E ++H +E ++ +QK EDI I++ ++LE++ + + +LSH L +E EE
Sbjct: 13481 EAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEEL 13540
Query: 2117 RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEAL------SMAVDDRAFME 1956
L+ + +E + ++E++ + R+ R ++ LKE + ++ D+ ++
Sbjct: 13541 ERLLEKERDDIENCKKIIESEKQSIERE----RAELKRLKEEVEVQHERTLLQQDKNMIQ 13596
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIE 1776
K+ + LE +K ++E+ ++ +S+L L+++ E+ + + E
Sbjct: 13597 KEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQE---------------E 13641
Query: 1775 KLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILK---QDINIE---DE 1614
+L+G + ++E+ L K+ D+ + K ++ Q+ LK +D + DE
Sbjct: 13642 ELHGLPEEIEIEDHLKKED-----DVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDE 13696
Query: 1613 LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
+ +T E + A + + AK ++++ + +V +++ + I L ++
Sbjct: 13697 ITKTDERRQRALEETVATT---AKQPIVIKLEDTLTSEVQEMRDHLNNEIKELARMKTIM 13753
Query: 1433 QVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKEL 1254
++ +Q++ KS++ + E + + E + L++L + L + + KE+
Sbjct: 13754 KMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLDKKNKEI 13813
Query: 1253 WN---------AKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNV 1101
N A+ V+ K +N L+ + Q ++ +IQ + +V +E +
Sbjct: 13814 ENNTETFLKKIAQLETTIVLMKKDKENIENELLQLK---QIEQEREIQRKADVTSTEKEM 13870
Query: 1100 LSSEVENLKSELKESKD 1050
+ +V K+EL++SK+
Sbjct: 13871 YTEKV-TYKTELEDSKE 13886
Score = 75.5 bits (184), Expect = 1e-10
Identities = 134/627 (21%), Positives = 266/627 (42%), Gaps = 97/627 (15%)
Frame = -1
Query: 2189 NNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDV 2010
N LE + E+ ++ + E+ R +L DMQ +EQM + E+EE+ Q + ++
Sbjct: 2011 NRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEK 2070
Query: 2009 NHLKEALSMAVDDR------AFMEKQ-LQD--LENQKETVS-KELALSVSREQKLASDLK 1860
+ L+ L +D EKQ L+D +E QKE +A R+++ ++
Sbjct: 2071 DKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIR 2130
Query: 1859 ALSEKEEST--------KNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIY 1704
EK+E T + + I Q + ++ +I+ + Q E + E+I
Sbjct: 2131 VGIEKQEITFKDLKADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLVEEIE 2190
Query: 1703 DLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKV---SG 1533
K L EV +++ + + +E E ++ +E + K+ N+ A++ S
Sbjct: 2191 KRTKALDEMQMEVDKERQEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESD 2250
Query: 1532 ILEML---LPMKDDVFSLKEEVLG-----------NINSLRNDAQMVQVALEQMQDTKSE 1395
LE+ + + +F L++E LG I+ L+N +M +V +EQMQ K +
Sbjct: 2251 NLELQSENISKERTIFELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQ 2310
Query: 1394 LFAEAEI--------------RAQEVLRLQAEVDAIQ----HI-----LIELKRKNQTLQ 1284
+AE + QE+ L+ E + ++ H+ L E + K+ ++
Sbjct: 2311 QRKKAEYVKTARGRETTALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEME 2370
Query: 1283 DESQRNAKELWNAK-----------ARLNNVMSKNINLESQN-RSLKAELHLQA----QK 1152
+E+ + KE + + + M + +E++N K EL +Q +
Sbjct: 2371 NEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTE 2430
Query: 1151 AFQIQEERNVVE-SEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIE 975
+ ++ ++ VVE S+ + L + + ++L E + + +++ + + Q + +
Sbjct: 2431 TYMLETQKPVVEKSKTDELDEVRKKINADLSEVEKQKSALVQM-NLKISQEESYVKKEKD 2489
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGN 795
+ E + + +L +NE + +A E E +NV R E V I+K
Sbjct: 2490 RLKLQENEQNMQMSQLNAKQNELD--ERQAEMEKQKRELENVM-DRLEKEKVEITKE--K 2544
Query: 794 GRANQREFQNKEEDSSGVDLLKNKCTR-----------LEFQVQKLSEK----AEMFETK 660
R N+ + + K +++S VDL+K + R L +++K+ EK AE FE
Sbjct: 2545 QRVNEMQNEVKRKNAS-VDLIKQEVLREQDHIENSREILNRELEKIKEKKTILAEEFEAL 2603
Query: 659 -------SREAQQMANKLEEMQQTLSD 600
+E Q++ E+Q+ D
Sbjct: 2604 DDKKEMIGKEMQRLGKMKAELQKEAED 2630
Score = 75.5 bits (184), Expect = 1e-10
Identities = 144/718 (20%), Positives = 298/718 (41%), Gaps = 33/718 (4%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQE-N 2127
K + +L +E + +L N + + N D L I+ + LE+ I +L K ++ +
Sbjct: 13102 KTLKQLKDENESKRTQLD---NTIEKMNMDK-LSIQREKDSLEE---IKADLQRKAEKLD 13154
Query: 2126 EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL 1947
EE R A+Q Q +++ +L DD +E SM RA +E+Q
Sbjct: 13155 EEMRKAVQITSQ---------------ISQDAKILDDDREKEEELRSM----RADIERQA 13195
Query: 1946 QDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLY 1767
+ LE+ + + E + + K +DL +++ +N L +Q EL EK
Sbjct: 13196 KILESDVQLLQTE--KEILEKSKTENDLLREDLEKQRKRNDLTLQ-------ELRKEK-- 13244
Query: 1766 GSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGR 1587
+ ++QM + K+ + + L ++ K E++ ++ + +Q + D+L E+ +
Sbjct: 13245 --MALEQMITDITKE-KDAVASLQNEVSLKQHELKNKETELDEQRKEM-DDLRMQLEMRQ 13300
Query: 1586 SATDMKKVNSDA----GAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALE 1419
++T+ ++ D K+ LE + + D+ ++ + +N +
Sbjct: 13301 NSTNKQQQEVDVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAV 13360
Query: 1418 QMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKA 1239
Q D + + + + V + + E+D + +I+ K + Q+L E + +E+ +A
Sbjct: 13361 QQTDELEKFTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRA 13420
Query: 1238 RLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKE 1059
++ ++ +L + +K + + Q A + E++ VE + N+ + +N EL+
Sbjct: 13421 QIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNL--QKQKNELEELRN 13478
Query: 1058 SKDLEGYFLRLFEILLG---QHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNE 888
+ + E + + +I+L + VE I+S R EK L++L + NE + + E
Sbjct: 13479 TIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQE 13538
Query: 887 ALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLE 708
L + ER ++ + S +S+ RA + + + E LL+ ++
Sbjct: 13539 ELERLLEKERDDIENCKKIIESE--KQSIERERAELKRLKEEVEVQHERTLLQQDKNMIQ 13596
Query: 707 FQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVR-------- 552
EK + K+R +++ N EE+++ S++
Sbjct: 13597 ------KEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQEEELHGLPEEI 13650
Query: 551 ----SLKKENTRLRSEM--KGELTPSRSFKHREGS-------FIKEINIGDEDDTPLIQX 411
LKKE+ LR E+ K + S+ F+ + S + EI DE ++
Sbjct: 13651 EIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRALEE 13710
Query: 410 XXXXXXXXXXKI---DTRTSETQEIDTLMDDNRKYWNRVSHFTK-QTQSLQNSVQELQ 249
I DT TSE QE+ +++ K R+ K + L+ + ++Q
Sbjct: 13711 TVATTAKQPIVIKLEDTLTSEVQEMRDHLNNEIKELARMKTIMKMEKDQLKQAKSDIQ 13768
Score = 75.1 bits (183), Expect = 1e-10
Identities = 109/585 (18%), Positives = 249/585 (42%), Gaps = 36/585 (6%)
Frame = -1
Query: 2156 VELSHKLQENEEQ-RSALQNDMQSVE-QMHAVSQ--TEREELNRQLVLLRDDVNHLKEAL 1989
+E KL E +Q R+ + N Q ++ Q +++ TE+ +L R + ++ +++H++E +
Sbjct: 145 IEQIEKLWEGTKQERTEIDNMKQKIQRQQDEITRMTTEKGQLERTITHMKAEIDHIRERM 204
Query: 1988 SMAVD----DRAFMEKQLQDLENQKETVSKELALSVSREQKL-------ASDLKALSEKE 1842
+ +R +E+ DL+ ++ ++ ++ ++ Q L + L
Sbjct: 205 DRNKEEVNRERERVEQMRSDLQAEQSSLQQKRDEIMTERQNLEMIRYETLRQQEELESNR 264
Query: 1841 ESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQ 1662
ESTK+++ + ++++I ++ + Q L++ +I D L K +++
Sbjct: 265 ESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLMEQMKAEIEDEKNELEKKKEDIK 324
Query: 1661 GQQEGILKQDINIEDELARTK-EVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLK 1485
Q++ Q I+ +L + K E+ + + +K + A + E L ++D++ ++
Sbjct: 325 RQRD----QFEQIKLDLQQVKMEMEQRWHETEKEGLEQRAVIQREKEQLKYLQDEIQRVR 380
Query: 1484 EEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELK 1305
EEV N R ++ + Q++ E E + ++LR + +++ ++H E++
Sbjct: 381 EEVERN----REFSKQEHARISQLRAQALEENNLIENKWHDILRKEKDLEEMKH---EIE 433
Query: 1304 RKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERN 1125
R + L + KE + ++ S I++E + +K E ++Q +++
Sbjct: 434 RGREELVMNGELVKKEWEKIEQAKVDIQSHMISMEGRVDEIKRETERLKHIKTEMQRDKD 493
Query: 1124 VVESE---------------HNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVA 990
+E + + +++ E+E+ +E +LE + + + ++
Sbjct: 494 ALEKQKDDTRKAKEEAERKRYEIVTEELEHRARLQRERDELENIRAEMQRVNDVEKAKIL 553
Query: 989 SLDIESCRFAEE-KLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLI 813
ES R EE + R EL+ NA++K E ER N R E M +
Sbjct: 554 KEKEESIRIREEARQERETTELV-----NAEIKAEK-------ERLN---QRQEEM---L 595
Query: 812 SKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMAN 633
+ R + KEE + D+ + ++E ++ + E E K E Q+
Sbjct: 596 RERQEIERIKHETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKE 655
Query: 632 KLE----EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK 510
++E E+++ D+ + L+ E R++ EM+
Sbjct: 656 QMEEAKVELEEEREDLERKRDLVSREIEQAEFLRNEILRVKEEME 700
Score = 75.1 bits (183), Expect = 1e-10
Identities = 143/796 (17%), Positives = 329/796 (41%), Gaps = 40/796 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNL--LEQKDNIIVELSHKLQEN 2127
E+ R+ E ++ T +Q + ++ D+ K N + L Q+ +++ +
Sbjct: 7418 ELERIKTESQRATEHMQSH---AEERAGDLGEKEPVNTRIQRLIQEAEKASKMAWSTKHE 7474
Query: 2126 EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL 1947
E R +Q ++ SVE+ ER++++ + + ++ H +E L D+ K+
Sbjct: 7475 PEMR--MQREV-SVEE----ESVERQDMSANMQRMILEIEHARETLRGMKDEVQAARKER 7527
Query: 1946 QDLENQK-ETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQN----KQLELE 1782
+LEN K E ++ + + + EQ+ + + EK++ +++L+ E+N + +LE
Sbjct: 7528 SELENMKLEFLTMKKNMEKTYEQQ---NDEIQKEKQQIESSKMLLSRERNDLEQNRADLE 7584
Query: 1781 IEKLYGSLQMKQM--ENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELA 1608
+K +L +++ EN LL+ + + + L + E ++ Q + E
Sbjct: 7585 RQKQIMALDKQKLLAENELLEREKADVIKIIENLESLREEATRERATETAQATRRDSEEL 7644
Query: 1607 RTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQV 1428
K S D ++ + + ++ ++ L+ +K D+ + E+ L+ QM +
Sbjct: 7645 MQKMEALSMEDFQEASKNQMVELKRQIDKLIELKADLLQQQTELKKTKADLKQ--QMDDL 7702
Query: 1427 ALEQMQDTKSELFAEAEIRAQEVLRLQAEVD----AIQHILIELKRKNQTLQDESQRNAK 1260
+ + K E +++ R E++ +Q + D IQ + +E KR + L+ E K
Sbjct: 7703 EKTRSEILKHEKDTDSKTRELELIEIQRQKDDLETRIQKLTLE-KRDLEVLRSEIVLEKK 7761
Query: 1259 ELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVEN 1080
+L ++ + + S + E++ + Q+ ++ + +L N
Sbjct: 7762 DLDQKMKQVIRKRDEMEKIRSDIANATEEINRERQELEILRNNVQSARHDFELLLERTAN 7821
Query: 1079 LKSELKESKDLEGYFLRLFEIL---------LGQHVEVASLDIESCRFAEEKLMRILDEL 927
L+ E + D+E L + +I + + +E + ++I+ + ++ R + ++
Sbjct: 7822 LEDEESAATDIERLVLEVVKIREMVRNLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDI 7881
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRA---------EAMSVLISKSLGNGRANQRE 774
+R L E E +++ + RA E+M ++ K + E
Sbjct: 7882 GQIRENLGGLGEE--IEKTRRDKRELEKMRAELAEKQQEQESMREMLHKEREELEQLKDE 7939
Query: 773 FQNKEED----SSGVDLLKNKCTRLEF-QVQKLSEK----AEMFETKSREAQQMANKLEE 621
++ED V+ + +K EF +QK E+ E TK R+ Q+ + +++
Sbjct: 7940 INREKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNSDVQD 7999
Query: 620 MQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIG 441
++QT+ ++ + K+ +L + K EL +E +I E I
Sbjct: 8000 LRQTIEEINIQHGKKRAELEGIGFELKKGEQLLEKQKDEL--------KENGWIVE-EIK 8050
Query: 440 DEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSV 261
++ D+ ++ +D + ++ MD R S +Q + L+ S+
Sbjct: 8051 NKKDS--LEKINMEILRKNEDMDKEKGKLRQEKQEMDLFR------SELQRQREDLETSI 8102
Query: 260 QELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAW 81
Q+L + + I + K+L+ + Q++ ++ K F
Sbjct: 8103 QKLTHEKREME------------VLRSEIVLEKKDLDQKMKQVIRKRDEME---KIRFDI 8147
Query: 80 ANSMHDLNGQEQKLKV 33
AN+ +++G+ Q+L++
Sbjct: 8148 ANARVEIDGERQELEI 8163
Score = 75.1 bits (183), Expect = 1e-10
Identities = 126/646 (19%), Positives = 248/646 (38%), Gaps = 31/646 (4%)
Frame = -1
Query: 2279 EEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQN 2100
EEK +L + + E I K + +EQ EL ++Q E+Q +Q+
Sbjct: 9119 EEKNEMADLSRELQKAKDELEKIAYKTNKERHEVEQMQ---AELHSQIQAIEQQGQIMQD 9175
Query: 2099 DMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKET 1920
+E+ Q + EE+ + + HL L + +E D+E K+
Sbjct: 9176 KQNHLEEKELSIQRKEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQK 9235
Query: 1919 VSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQME 1740
+K+ L +L ++ L E K+ + +Q ++ ++ + +EK+ LQ
Sbjct: 9236 NNKDFELLEKIRSELENEKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQ----- 9290
Query: 1739 NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDIN-IEDELARTKEVGRSATDMKKV 1563
S+ Q ++E K D+N + E+ R K+V D K+
Sbjct: 9291 ---------------------SKREQTEKE---KADLNRVNAEIQREKQV----IDKKRH 9322
Query: 1562 NSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAE 1383
++ +E L +K ++ +E++ L + +VQ+ E + E+ +
Sbjct: 9323 MTNRA------MEELETIKTELKERQEKIQTEQEKLEEEKLLVQIEAENLNKVLEEIKRQ 9376
Query: 1382 AEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRN----------AKELWNAKARL 1233
E L+ + ++ E +RK ++++ Q N K++ K L
Sbjct: 9377 QEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQKQEL 9436
Query: 1232 N--------NVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEH---------- 1107
+++ N+E RSL E L QKA +I +R+ +E E
Sbjct: 9437 QKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNKL 9496
Query: 1106 NVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL 927
+VL +E++N ++E K +++ R K + L+E
Sbjct: 9497 DVLQNEMQNENKAMEEIK----------------------YELDGKRNEINKEQQRLEES 9534
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSS 747
+ NE K + DYE++ + E M V + + + KE D
Sbjct: 9535 LRAINEE---KGDLEIMRADYEKQE---QQIEEMRV------------EAKMERKELDQI 9576
Query: 746 GVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXX 567
+L K+K T ++++ +KL+ M E + + ++M ++L +Q + D
Sbjct: 9577 KSELEKDK-TEIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKE 9635
Query: 566 XIRVRSLKKENTRLRSEMKGELTPSRS-FK-HREGSFIKEINIGDE 435
+ ++N + + E+ R+ FK +E ++ NI DE
Sbjct: 9636 ANTEKDKIEKNKEIVERLMAEVEEQRNDFKLKKEELALERQNIVDE 9681
Score = 75.1 bits (183), Expect = 1e-10
Identities = 118/636 (18%), Positives = 280/636 (44%), Gaps = 27/636 (4%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLE-QKDNIIVELSHKLQEN 2127
KE S L + +Q +E + + ++ E + ++E + ++ QK+ + +E E
Sbjct: 9915 KERSELDNKIQQTDLE-KHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDIERQKIADEQ 9973
Query: 2126 E---EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFME 1956
+ + +S LQN+ + + ++ V + ERE L KE + ++ M+
Sbjct: 9974 DLLIQNKSELQNENERIRNINEVIKKERETL--------------KEMEAHLEKEKEEMK 10019
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIE 1776
++ QKE + K + Q L L +++E ++ ++ + + ++
Sbjct: 10020 SITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQVS 10079
Query: 1775 K-----LYGSLQMKQMENTLLKDGNEKIYDL---CKLLATKSREVQGQQEGILKQDINIE 1620
K L +MK+ E L++ +I ++ +L K + + ++E ++ + ++
Sbjct: 10080 KQKEEDLTKQKEMKE-ERKSLEETKARIIEMKTKAELEDIKKEKEKEEEEEEMRVKVEMD 10138
Query: 1619 DELARTKEVGRSATDMKKVNSDAG---AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRN 1449
KE+ R +++K+ S+ K++ +++ K ++ +K E++ +
Sbjct: 10139 G-----KELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKSEIMKQRQQMEE 10193
Query: 1448 DAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQ- 1272
+ ++ ++Q K ++ EI + ++ ++ + IQ EL + Q + DE
Sbjct: 10194 ERSELENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDL 10253
Query: 1271 --RNAKELWNAKARLNNVMSKNINLESQNRSLK-AELHLQAQKAFQIQEERNVVESEHNV 1101
+N EL N R+ N+ N ++ + +LK E HL+ +K EE V E
Sbjct: 10254 LIQNKSELQNENERIRNL---NEIIKKERETLKEMEAHLEKKK-----EEIKSVSEETRR 10305
Query: 1100 LSSEVENLKSEL-KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL- 927
L ++E + +++ K++KD L+ Q ++ + E ++L + +DE
Sbjct: 10306 LKEDLEKMSTDVNKQNKD-----------LMNQR-DLLEQEREEINHKWKQLQQRIDEFD 10353
Query: 926 --ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEED 753
+ + E K + + E +RK++ ++A + + +K+ ++E +N+EE+
Sbjct: 10354 AQVSKQKEQDLPKEKGMKE----DRKSLEETKANVIE-MKTKAEPEEIKKEKEKENEEEE 10408
Query: 752 SSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXX 573
E +V +E+ E+++ KS E +++ ++++ Q+ L+D
Sbjct: 10409 EE----------EEEIRVIVETERKELYQIKS-ELERVRSEIDHEQKKLNDYMKMIEQEK 10457
Query: 572 XXXIRVRS-LKKENTRL---RSEMKGELTPSRSFKH 477
+++S + K+ ++ RSE+ ++ + KH
Sbjct: 10458 EDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKH 10493
Score = 74.3 bits (181), Expect = 2e-10
Identities = 113/597 (18%), Positives = 256/597 (42%), Gaps = 32/597 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNL------LEQKDNIIVELSHK 2139
E RL + +++ E QE R K+E + K E N+ E+ + + E+ +
Sbjct: 583 EKERLNQRQEEMLRERQE---IERIKHETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQ 639
Query: 2138 LQENEEQRSALQNDMQSVEQMHAVSQTEREELNR----------QLVLLRDDVNHLKEAL 1989
+++ E++ +Q + +E+ + ERE+L R Q LR+++ +KE +
Sbjct: 640 IEDIEKKVEEIQKTKEQMEEAKVELEEEREDLERKRDLVSREIEQAEFLRNEILRVKEEM 699
Query: 1988 SMA--------VDDRAFMEKQLQDLEN-QKETVSKELALSVSREQKLA--SDLKALSEKE 1842
V+ RA + +L+ LE ++ET + + S+ + + L L +
Sbjct: 700 ESRWRETETEEVELRAKTQHELERLEKLREETERSQKNIEESKIELMLWKESLDKLKGEM 759
Query: 1841 ESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQ 1662
E K+ +++Q + K E ++ + L++++ E T+ ++ ++ D + + +
Sbjct: 760 EEDKHVVIMQMNEAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQH 819
Query: 1661 GQQEGILKQDINIEDELARTKEVGRSATDM--KKVNSDAGAKVSGILEMLLPMKDDVFSL 1488
+ E + +N E E A ++ +M KK ++ + ++ L +D++
Sbjct: 820 AEMEDWFRV-VNKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKK 878
Query: 1487 KEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIEL 1308
EE + + + Q + LE+M+ + E + ++ + + V+ ++ L++
Sbjct: 879 AEE----LEQINKEIQRARQELEKMRYFEKESLQKM---LEDTQQERVFVEQVRSELLKN 931
Query: 1307 KRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEER 1128
K E KEL + ++ N + +LE + + + +++ Q+Q ++
Sbjct: 932 KADQDKCLFEMDSERKELEQMRFQVEN---EKKDLEQRRYEM---MRYDVEQSAQVQRQK 985
Query: 1127 NVVESEHNVLSSEVENL-KSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEK 951
+E + L + E++ +S +D E L + EI + E + +E + EE
Sbjct: 986 EELEKIKSQLVIDTESMNRSRELARQDREKAELLIVEIQ--EQREDVNKRLEETKQREEA 1043
Query: 950 LMRILDELICLRNENAKLKNEALYEYHDYE--RKNVSGSRAEAMSVLISKSLGNGRANQR 777
L + ++ R + K++ E L YE ++ ++ RAE + G+ ++
Sbjct: 1044 LRLLRKDMENEREDLEKIRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREK 1103
Query: 776 EFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTL 606
KEE ++ +K + +E +L+++ E + K A+ LE M+ L
Sbjct: 1104 INHEKEEMIRKMEAMKREMGEIEDMKVELTKQKENIDMKMEHARLEMTNLEMMKADL 1160
Score = 71.6 bits (174), Expect = 1e-09
Identities = 115/638 (18%), Positives = 266/638 (41%), Gaps = 70/638 (10%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDI-----------CLKIEANNNL------LE 2175
+E++ L EE K+ + E++ +R++ E I + N N+ ++
Sbjct: 6332 EEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQ 6391
Query: 2174 QKDNIIVELSHKLQEN----EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVN 2007
QK N + ++S ++ + E+++ +Q + +E+MH Q ++E + L + D+
Sbjct: 6392 QKRNALEKMSKEISRDRMKLEDEKKEIQLAREELERMHGDMQRQQEAKDHLLSGITDESL 6451
Query: 2006 HLKEALSMAVD----DRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKA------ 1857
K + + D+A ++ + ++ K+ V + + + L D ++
Sbjct: 6452 LKKSEAEIVLQPSQVDKAKPARKTEISDSDKQPVFVQQMPEMDLKDALKKDFESEKLDLP 6511
Query: 1856 -----LSEKEESTKNQLLIQTEQNK--QLELEIEKLYGSLQMKQMENTLLKDGNEKIYDL 1698
L + ++ Q LI+ E +K Q+ E++K ++ K+ + +++ +K+ D+
Sbjct: 6512 KVKDVLPQDQQMKLEQKLIEDEMDKLKQMRAELQKEADQIEKKKQD---MQNERQKLDDM 6568
Query: 1697 CKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEML 1518
L + R + E I Q +N + + + TD +++ ++ + +
Sbjct: 6569 AARLQEERRTNERLNEEINIQKVNQQKQATAFQ---MEKTDFERIKTEIDQANKELADQQ 6625
Query: 1517 LPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEV 1338
K + +++E N ++ V+ + + S A+++ +++L+ Q E+
Sbjct: 6626 EKNKKTITEMQKERETLEEMRANISKQVETITNENKSLSSRESELAKLQ-EDILQQQQEM 6684
Query: 1337 DAIQH-ILIELKRKNQT----------LQDESQRNAKELWNAKARLNNVMSKNINLESQN 1191
D +++ I++E+ + +Q + D E+ N + V+++ N++S
Sbjct: 6685 DELKNTIMMEMCQLDQRQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQTRNIKSDM 6744
Query: 1190 RSLKAELHLQAQKAFQIQEERNVVESEHNVLSS--------------EVENLKSELK--- 1062
SLK E Q ++ EE++++E E +L+ E+ENLK E +
Sbjct: 6745 VSLKMEKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIK 6804
Query: 1061 -ESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL-ICLRNENAKLKNE 888
E K+LE + L +G E + + EE + +L I R K E
Sbjct: 6805 NEKKELEKMKISLQRKAIG-FKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEE 6863
Query: 887 ALYEYHDYERKN-VSGSRAEAMSVLISKSLGNGRANQRE-FQNKEEDSSGVDLLKNKCTR 714
L + RK + + + K+ ++ E ++ + E + + LK T
Sbjct: 6864 RLDQTEKKRRKTYYTEDLFQEEKTDLQKTKEEINYDREEIYRQRTELNKEKETLKQMHTS 6923
Query: 713 LEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSD 600
+++ + ++ E + E Q+ +L+ Q+ + D
Sbjct: 6924 NLKEIENIEKEKEKIQRTWNELDQIRAELQNKQRDMDD 6961
Score = 70.9 bits (172), Expect = 2e-09
Identities = 128/646 (19%), Positives = 260/646 (40%), Gaps = 99/646 (15%)
Frame = -1
Query: 2258 ELQENFNALRQ-----KNEDICLKIEANNNLLEQKD--NIIVELSHKLQENEEQRSALQN 2100
ELQ +R KNE LK + ++K+ +II E S + ++ E+ + +
Sbjct: 9691 ELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNV 9750
Query: 2099 DMQSVEQMHAVSQTEREELNRQLVLLRDDVNH-------------------------LKE 1995
Q ++ + EREE+N + + ++ L+E
Sbjct: 9751 QKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEE 9810
Query: 1994 ALSMAVDDRAFME-------KQLQDLENQKETVSKE--------LALSVSRE-------- 1884
++ + E +++++L+ +E + KE + L + RE
Sbjct: 9811 VNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSE 9870
Query: 1883 ------------QKLASDLKAL-SEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQM 1743
+KL D+K + EKE+ K + I T Q +++E E +L +Q +
Sbjct: 9871 LVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMT-QKQEMEKERSELDNKIQQTDL 9929
Query: 1742 ENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDE----LARTKEVGRSATD 1575
E ++ E + L + + E+Q Q+E + + I DE + E+
Sbjct: 9930 EKHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDIERQKIADEQDLLIQNKSELQNENER 9989
Query: 1574 MKKVNSDAGAKVSGILEM---LLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDT 1404
++ +N + + EM L K+++ S+ EE L + ++ + +
Sbjct: 9990 IRNINEVIKKERETLKEMEAHLEKEKEEMKSITEETRRQKEDLEKMSTDIKEQNQDLMKQ 10049
Query: 1403 KSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNV 1224
+ L E E E +LQ +D + + K ++ T Q E + K L KAR+ +
Sbjct: 10050 RDLLEQEKEDINHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEM 10109
Query: 1223 MSK----NINLESQNRSLKAELHLQAQK--------AFQIQEERNVVESEHNVLSSE--- 1089
+K +I E + + E+ ++ + +++ ER+ ++ E L+ +
Sbjct: 10110 KTKAELEDIKKEKEKEEEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKI 10169
Query: 1088 -------VENLKSE-LKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILD 933
+E +KSE +K+ + +E L + ++E DIE+ + +KLM ++
Sbjct: 10170 IEQEKQNLEKMKSEIMKQRQQMEEERSELENKIKQTYIE--KCDIENSKEIVQKLMVEVE 10227
Query: 932 ELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEED 753
E + + + E L D ER+ + A+ +LI N+ E QN+ E
Sbjct: 10228 E----QKHEIQFQKEEL----DIERQKI----ADEQDLLIQ--------NKSELQNENER 10267
Query: 752 SSGV-DLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEM 618
+ +++K + L+ L +K E ++ S E +++ LE+M
Sbjct: 10268 IRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRLKEDLEKM 10313
Score = 70.1 bits (170), Expect = 4e-09
Identities = 121/594 (20%), Positives = 247/594 (41%), Gaps = 45/594 (7%)
Frame = -1
Query: 2258 ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQ 2079
+++EN L ++ IE + + + EL+ K QE E R L + + +EQ
Sbjct: 7883 QIRENLGGLGEE-------IEKTRRDKRELEKMRAELAEKQQEQESMREMLHKEREELEQ 7935
Query: 2078 MHAVSQTERE--ELNRQLV----------------LLRDDVNHLKEALSMAVDDRAFMEK 1953
+ E+E E+ R+LV ++++ + E L D +
Sbjct: 7936 LKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNS 7995
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEK 1773
+QDL E ++ + + + + +LK + E K++L ++N + EI+
Sbjct: 7996 DVQDLRQTIEEINIQHGKKRAELEGIGFELKKGEQLLEKQKDEL----KENGWIVEEIKN 8051
Query: 1772 LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSR------EVQGQQEGILKQDINIEDEL 1611
SL+ ME +L+ + + KL K E+Q Q+E L+ I
Sbjct: 8052 KKDSLEKINME--ILRKNEDMDKEKGKLRQEKQEMDLFRSELQRQRED-LETSIQKLTHE 8108
Query: 1610 ARTKEVGRSATDMKKVNSDAGAK-VSGILEMLLPMKDDVFSLKEEVLG---NINSLRNDA 1443
R EV RS ++K + D K V + + ++ D+ + + E+ G + LR++
Sbjct: 8109 KREMEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRFDIANARVEIDGERQELEILRDNV 8168
Query: 1442 QMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNA 1263
Q + E++ + + L E E A ++ RL EV I+ ++ LK + + +ES+
Sbjct: 8169 QSARQDFERLVERTANLEVE-ESAATDIERLVLEVVKIREMVRNLKGEMERRMEESKVEI 8227
Query: 1262 KELWNAKARLNNVMSKNINLESQNRSLKAEL--------HLQAQKAFQIQEERNVVESEH 1107
E K+ + ++ + LK E+ +L+ KA +++E++ ES
Sbjct: 8228 DEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKA-ELEEKQQEEESMR 8286
Query: 1106 NVL---SSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRIL 936
+L E+E LK ++ K+ L E + + D++ + E+L +
Sbjct: 8287 EILQKEKEELEQLKKDINREKEDIEISRELVESEIYEGEVKGFTDVQKYK---EELQIVT 8343
Query: 935 DELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEE 756
+EL+ + +L ++ + E ++ + +A I+ + R E Q K+
Sbjct: 8344 EELLTKKRNLEQLNSDVQHLMQTLEEVDIQYIKKKAELEHITSEI-QKREQILEKQKKKL 8402
Query: 755 DSSG-----VDLLKNKCTRLEFQV-QKLSEKAEMFETKSREAQQMANKLEEMQQ 612
+ +G ++++K + ++ QK + + E RE Q+ E+Q+
Sbjct: 8403 EENGWIIEEIEMMKVTLESINMEILQKREDMEKEKENLRREKQETELFRGELQR 8456
Score = 69.3 bits (168), Expect = 7e-09
Identities = 125/585 (21%), Positives = 244/585 (41%), Gaps = 25/585 (4%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEE 2121
EVS E K EL E R++ +D+ +++E N ++ E+ + EN +
Sbjct: 13267 EVSLKQHELKNKETELDEQ----RKEMDDLRMQLEMRQNSTNKQQQ---EVDVFIVENMK 13319
Query: 2120 QRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQD 1941
R ND++S M + ER +L + D N L + + AV +EK D
Sbjct: 13320 MR----NDLES---MKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTD 13372
Query: 1940 LENQKETVSKEL-ALSVSREQ--KLASDLKALSEKEESTKNQLLIQTEQNKQLE-LEIEK 1773
++ +KE V KE + V ++ K +L++L+ + E K ++ + Q + LE L +
Sbjct: 13373 IKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADL 13432
Query: 1772 LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEV 1593
L G+ +K + T + E K EV+ Q L++ N +EL T E
Sbjct: 13433 LAGADDIKTLVQTEKQMAIED--------TEKKTEVELQMN--LQKQKNELEELRNTIEA 13482
Query: 1592 GRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRND-AQMVQVALEQ 1416
+ + +K+ D K + ++ + DV ++ L ++ + N+ Q Q LE+
Sbjct: 13483 EKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELER 13542
Query: 1415 MQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKAR 1236
+ L+ E D I++ ++ + Q++ +R EL K
Sbjct: 13543 L--------------------LEKERDDIENCKKIIESEKQSI----ERERAELKRLKEE 13578
Query: 1235 LNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVE------SEHNVLSSEVENLK 1074
+ + + + +N K + HL+ +KA +E N+ E SE ++L+ E+E +
Sbjct: 13579 VEVQHERTLLQQDKNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKR 13638
Query: 1073 SE-----LKESKDLEGYFLRLFEILLGQHVEVASLDIE-------SCRFAEEKLMRILDE 930
E L E ++E + + ++L + ++ D + R AE + LDE
Sbjct: 13639 QEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTS--LDE 13696
Query: 929 LICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKE--E 756
+ + + + AL E V+ + + + + + +L + R+ N E E
Sbjct: 13697 I----TKTDERRQRALEE-------TVATTAKQPIVIKLEDTLTSEVQEMRDHLNNEIKE 13745
Query: 755 DSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEE 621
+ ++K + +L+ + + E FE EA + ++ EE
Sbjct: 13746 LARMKTIMKMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNEE 13790
Score = 69.3 bits (168), Expect = 7e-09
Identities = 86/415 (20%), Positives = 173/415 (41%), Gaps = 36/415 (8%)
Frame = -1
Query: 2180 LEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHL 2001
++Q H +++EE+ SA + +V ++ +E +E+ L +DV +
Sbjct: 14374 IQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVARM 14433
Query: 2000 KEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQL 1821
K + M D +E+ D++ Q E + + ++ + + L L+ +E N L
Sbjct: 14434 KTIMKMEKDQ---LEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTL 14490
Query: 1820 LIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKI-YDLCKLLAT-KSREVQ----- 1662
++NK++E E + + L+K E I +L +L T + RE+Q
Sbjct: 14491 ---DKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQEREIQRGTDD 14547
Query: 1661 -GQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDA-GAKVSGILEM---------LL 1515
+ + + + EL KE + D +DA AK G E +L
Sbjct: 14548 TSNEREKYDEKVTYKTELEDNKEKKKPDRDSSLKLTDADSAKTDGEREAQTLETKVQDVL 14607
Query: 1514 PMKDDVFSLKEE----------VLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQ 1365
+ DD +EE ++ +N + D Q ++ ++ KS + E R
Sbjct: 14608 QLTDDTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEKCRSAEEEKSVIMESLERRRN 14667
Query: 1364 EVLRLQAEV----DAIQHILIELKRKNQTLQDESQRNAKEL---WNAKARLNNVMSKNIN 1206
+ ++Q+EV I+H L ++K + Q ++ + QR + + W ++ +
Sbjct: 14668 SLEKVQSEVLTLTQEIEH-LAQIKTEMQQIETKMQRQTRSVATQWETDVQIQQEGQEATE 14726
Query: 1205 LESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-KESKDLE 1044
+ + K+E + A+K ++ V + L+SEV+ ++ L KE +D+E
Sbjct: 14727 TRG-HITKKSEEEISAKKT-----KQPTVTKLEDTLTSEVQEMRDSLNKEMEDVE 14775
Score = 68.9 bits (167), Expect = 9e-09
Identities = 119/605 (19%), Positives = 261/605 (43%), Gaps = 46/605 (7%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQ 2103
E E + +E Q++ + + E+ ++ + + + N +L +LQ +EQ +
Sbjct: 8731 ELENRVFMEEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQREKEQLEISK 8790
Query: 2102 NDMQSVEQMHAVSQTEREELNRQLVLLR-------DDVNHLKEALSMAVDDRAFMEKQLQ 1944
N +EQ Q + L RQL LR D+ N L++ S + + + + K+ +
Sbjct: 8791 NQ---IEQEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKERE 8847
Query: 1943 DLEN-------QKETVSKEL-ALSVSREQ--KLASDLKALSEKEESTKNQLLIQTEQNKQ 1794
DLEN +K+ + +E L + RE+ K+ S+L+ E ES + ++ + E+ Q
Sbjct: 8848 DLENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINNKMEELLQ 8907
Query: 1793 LEL-------EIEKLYGSLQ--MKQMENTL--LKDGNEKIYDLCKL-LATKSREVQGQQE 1650
+++ EIEK LQ +EN ++ +K D+ + + K RE++ Q +
Sbjct: 8908 MKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQLD 8967
Query: 1649 GILKQDINIEDEL-ARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVL 1473
K+ + +E+ + K++ DMK+ + G+LE K ++ K+E+
Sbjct: 8968 ---KETKRLSEEIELKVKDLEMEMADMKRQKQEI-EDTKGLLE---KEKQELKQEKKELE 9020
Query: 1472 GNINSLRNDAQMVQVALEQMQDTKS---ELFAEAEIRAQEVLRLQAEVDAIQHILIELKR 1302
+ L + Q + + K+ +L E EI +++ ++ ++ +Q + + +R
Sbjct: 9021 DQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQR 9080
Query: 1301 KNQTLQDESQRNAKELWNAKARLNN-----VMSKNINLESQNRSLKAELHLQAQK----- 1152
N ++E+++ + L + +S +E +N LQ K
Sbjct: 9081 LNDQTREENKKEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDELEK 9140
Query: 1151 -AFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIE 975
A++ +ER+ VE L S+++ ++ + + +D + + L E+ + + E +
Sbjct: 9141 IAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQDKQNH-LEEKELSIQRKEEEIKIGNT 9199
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGN 795
+ +E L +L+ E K +++ D E ++ + I L N
Sbjct: 9200 EFQIEQEHLNNVLE-------ETNKRQHDLEVMRADIELNKQKNNKDFELLEKIRSELEN 9252
Query: 794 GRANQREFQNKEEDSSGVDL--LKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEE 621
+ + + + +++ V L L+ + RLE +L K E E + + ++ +++
Sbjct: 9253 EKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQTEKEKADLNRVNAEIQR 9312
Query: 620 MQQTL 606
+Q +
Sbjct: 9313 EKQVI 9317
Score = 68.6 bits (166), Expect = 1e-08
Identities = 116/606 (19%), Positives = 255/606 (42%), Gaps = 39/606 (6%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQK-NEDICLK----------IEANNNLLEQKDNII 2157
+ + +L +E ++ ++ E N RQ+ E+I LK I+ L II
Sbjct: 6992 ENIQKLMKELQEERLKTSEALNKERQQFTEEIKLKNDSLDEIQAEIDRQKRALVTDKEII 7051
Query: 2156 VELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAV 1977
+ LQ+ ++ R Q+D + + + Q ERE L++ V + L+ +
Sbjct: 7052 TKQMMDLQKTQDVRR--QSDESDIARANL--QRERESLDQLSVEILKQKQDLERERDELL 7107
Query: 1976 DDRAFMEKQLQDLENQKETVSKELALSVSREQ---KLASDLKALSEKE---ESTKNQLLI 1815
+ +E Q D EN K+ ++ L S E+ +L D + E + +L +
Sbjct: 7108 EQWRLVETQKMDNENVKQLKTELLDEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNL 7167
Query: 1814 QTEQNKQLELEIEKLYGSLQMK------QMENTLLK-----DGNEKIYDLCKLLATKSRE 1668
Q + + ++E++ G LQMK +M+ L + + + Y + L + E
Sbjct: 7168 QKQGIQDERAQLERMKGELQMKADDIERKMQEILYEKQKYAERKSENYKIQTYLDEANAE 7227
Query: 1667 VQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKV---SGILEMLLPMKDDV 1497
VQ + + + D N+E E+ ++ + ++V GAK+ I + L +D +
Sbjct: 7228 VQKLNKELERYDENLE---KCKLELDKARAETERVKQ--GAKIPETQQIEQSLQKERDYI 7282
Query: 1496 FSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHIL 1317
++ + ++ D +++ +++ ++++ + E ++ + + E IQ
Sbjct: 7283 EDIRRNLFKKEEAIEKDKAEIRLRHQELDLIQAKVVKQKEEMVKQKIESERE---IQQEK 7339
Query: 1316 IELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQ 1137
+L+R + L+D+ Q+ +E+ K + K +++++ R + A+K +++
Sbjct: 7340 KKLQRSEEELEDKMQKIKREMIELKLLQDETDGKRKDVDNKMRQV-------ARKRDELE 7392
Query: 1136 EERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAE 957
+ + VES L + L +E E + ++ R E + H E + D+
Sbjct: 7393 KMKADVESASKKLEVDRVMLNTERDELERIKTESQRATE-HMQSHAEERAGDLGEKEPVN 7451
Query: 956 EKLMRILDEL--------ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSL 801
++ R++ E +++ E E ER+++S + + M + I +
Sbjct: 7452 TRIQRLIQEAEKASKMAWSTKHEPEMRMQREVSVEEESVERQDMS-ANMQRMILEIEHAR 7510
Query: 800 GNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEE 621
R + E Q ++ S ++ +K LEF K + +E ++ E Q+ ++E
Sbjct: 7511 ETLRGMKDEVQAARKERSELENMK-----LEFLTMK-KNMEKTYEQQNDEIQKEKQQIES 7564
Query: 620 MQQTLS 603
+ LS
Sbjct: 7565 SKMLLS 7570
Score = 65.5 bits (158), Expect = 1e-07
Identities = 110/608 (18%), Positives = 255/608 (41%), Gaps = 40/608 (6%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIE--LQENFNALRQKNEDICLKIEANNNLLEQKDNI-----IVELSH 2142
E+ +L + E++ I+ + N +E + K E ++ ++K + + +
Sbjct: 14185 ELLQLKQTEQEREIQRGTDDTSNERENYDEKVTYKTELEDSKEKKKPDRDSSLKLTDADS 14244
Query: 2141 KLQENEEQRSALQNDMQSVEQMHAVSQTEREEL-----NRQLVLL-----RDDVNHLKEA 1992
+ E + L+ +Q V Q+ + ++EEL N+ ++L + D+ LKE
Sbjct: 14245 AKTDGEREAQTLETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEE 14304
Query: 1991 LSMAVDDRAFMEKQLQDLENQKETVSKELALSVSRE----QKLASDLKALSEKEESTKNQ 1824
A ++++ + + L+ N E V E+ LS+++E ++ ++++ + K +
Sbjct: 14305 CRSAEEEKSVIMESLERRRNSLEKVQSEV-LSLTQEIDHLAQIKTEMQQIEIKMQIQTRS 14363
Query: 1823 LLIQTEQNKQLEL--EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQE 1650
+ Q E + Q++ E + G + K E K + + KL T + EVQ ++
Sbjct: 14364 VATQWETDVQIQQGQEATETTGHITKKSEEEISAKKTKQPT--VTKLEDTLTSEVQEMRD 14421
Query: 1649 GILKQDINIEDELARTKEVGRSATD-MKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVL 1473
+ K+ +++AR K + + D +++ SD ++ + ++ +E++L
Sbjct: 14422 SLNKE----MEDVARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLL 14477
Query: 1472 G---NINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKR 1302
+ L N +E +T + A+ E ++ ++ + + I++ L++LK+
Sbjct: 14478 QLTHDKEDLSNTLDKKNKEIENNTETSLKKIAQLETT---IVLMKKDKENIENELLQLKQ 14534
Query: 1301 KNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNV 1122
Q + E QR + N + + + ++ LE K + + K +
Sbjct: 14535 TEQ--EREIQRGTDDTSNEREKYDEKVTYKTELEDNKEKKKPDRD-SSLKLTDADSAKTD 14591
Query: 1121 VESEHNVLSSEVENL----KSELKESKDLEGYFLRLFEILLGQHVEVASLDI----ESCR 966
E E L ++V+++ ++ ++L +I+L + A D+ E CR
Sbjct: 14592 GEREAQTLETKVQDVLQLTDDTTQDQEELHDEMENKMKIIL--ELNEAKKDLQKLKEKCR 14649
Query: 965 FAEEKLMRILDELICLRNENAKLKNEAL---YEYHDYERKNVSGSRAEAMSVLISKSLGN 795
AEE+ I++ L RN K+++E L E + + E ++S+
Sbjct: 14650 SAEEEKSVIMESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIETKMQRQTRSVAT 14709
Query: 794 GRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEK--AEMFETKSREAQQMANKLEE 621
+ Q + ++++ K + E +K + ++ +T + E Q+M + L +
Sbjct: 14710 QWETDVQIQQEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNK 14769
Query: 620 MQQTLSDM 597
+ + M
Sbjct: 14770 EMEDVERM 14777
Score = 63.2 bits (152), Expect = 5e-07
Identities = 127/614 (20%), Positives = 263/614 (42%), Gaps = 70/614 (11%)
Frame = -1
Query: 2231 RQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTER 2052
R + ++ I+ LE II++ H+L + +E A++ND + E+M + + E+
Sbjct: 1518 RASDLELSASIQKERQELEHYKEIILKEKHELNKIKEDVKAVKNDAE--ERMIKLHEEEK 1575
Query: 2051 EELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLA 1872
E +++ L E+QLQ +KE K L + Q+L
Sbjct: 1576 EMKTKRVSLQN-------------------WERQLQ---TEKEKNQKGLDAIWNENQQLN 1613
Query: 1871 SDLKALSEKEESTKNQLLIQTEQNK---QLELEIEKLYGSLQMKQMENTLLKDGNEKIYD 1701
+ L KE L +Q+E++K + LEI+++ +Q + ME+ D I +
Sbjct: 1614 ERKQQLDIKE------LHLQSEKSKLEYKKPLEIKQVDAQVQTELMEDASEYDMALSIEE 1667
Query: 1700 LCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEM 1521
L K + + ++ ++ +L Q +E ++A E+ R +++ + + +E+
Sbjct: 1668 LDK----QRQFLEYFKQELLAQKCTMERQMAEI-ELSRDELSLREATLQTATQTTADMEL 1722
Query: 1520 LLPM--------KDDVFSLKEEV-------LGNINSLRNDAQMVQVALEQMQDTKSELFA 1386
L + KD++ K EV I R +MV++ LE+ +D + +
Sbjct: 1723 QLELQKQELEQTKDEMERTKLEVQKGWVDLQTQIAESREKEEMVRIELEKARDVLNRIRQ 1782
Query: 1385 EAEIRAQEV-----LRLQAE---VDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLN 1230
+ E Q + L E ++A + ++ + KR + ++ E QR + + +K +
Sbjct: 1783 DVETEKQTMEADLKFTLAKEFENLEAQRKMMEDEKRALENMKYELQRESGYIERSK---H 1839
Query: 1229 NVMSKNINLESQNRSLK---AELHLQAQKAFQIQEER------------------NVVES 1113
N+ + N+E+ LK EL + Q+Q ER N +++
Sbjct: 1840 NMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERSREIKDLENLRELNELTLNQIKT 1899
Query: 1112 EHNVL----------SSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRF 963
+ +VL E+EN KS++K + Y L+ + L + + DI++ F
Sbjct: 1900 KSDVLEKISELNSQQKDEIENEKSKIK----IREYDLQQMQTDLNRQ-QKEMQDIQNAVF 1954
Query: 962 AEE-KLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRA----------EAMSVL 816
E+ +L + DE+ E K + + ++ E+ N+ RA M+ L
Sbjct: 1955 MEKSELKKSQDEIA----EQLKQVGD-MMQFTQNEKDNLDRERAAIIEQKLQMERDMTHL 2009
Query: 815 ISKSLGNGRANQREFQNKEE--DSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQ 642
+++ L + + ++E N++ + + L+++ + ++ EK EM + + + +
Sbjct: 2010 LNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEM-QLQRQSIAE 2068
Query: 641 MANKLEEMQQTLSD 600
+KLE + QTL++
Sbjct: 2069 EKDKLESVLQTLAE 2082
Score = 63.2 bits (152), Expect = 5e-07
Identities = 119/611 (19%), Positives = 253/611 (41%), Gaps = 43/611 (7%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQ---- 2133
E+ +L + E++ E+Q + + E K+ L + K+ I + L+
Sbjct: 13844 ELLQLKQIEQER--EIQRKADVTSTEKEMYTEKVTYKTELEDSKEKIKPDRDSTLELTDT 13901
Query: 2132 -----ENEEQRSALQNDMQSVEQMHAVSQTEREEL-----NRQLVLL-----RDDVNHLK 1998
+ E + L+ +Q V Q+ + ++EEL N+ ++L + D+ LK
Sbjct: 13902 DSAKTDGEREAQTLETKVQDVLQLTDDTTQDQEELHDEMENKMKIILELNKAKKDLQKLK 13961
Query: 1997 EALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSRE----QKLASDLKALSEKEESTK 1830
E A ++++ + + L+ N E V E+ LS+++E ++ ++++ + K +
Sbjct: 13962 EECRSAEEEKSVIMESLERRRNSLEKVQSEV-LSLTQEIDHLAQIKTEMQQIEIKMQIQT 14020
Query: 1829 NQLLIQTEQNKQLELEIEK---LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQG 1659
+ Q E + Q++ E ++ G + K E K + I + KL T + EVQ
Sbjct: 14021 RSVATQWETDVQIQQEGQEPIETTGHITKKSEEEISAKKTKQPI--VTKLEDTLTSEVQE 14078
Query: 1658 QQEGILKQDINIEDELARTKEVGRSATD-MKKVNSDAGAKVSGI---LEMLLPMKDDVFS 1491
+ D+ IED +AR K + + D +++ SD ++ +E L K
Sbjct: 14079 MR------DMEIED-VARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEETLKEKSRNEE 14131
Query: 1490 LKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIE 1311
++L + + L N +E + T A+ E + ++ + + I++ L++
Sbjct: 14132 TLLQLLHDKDDLSNTLDEKSKEIENITVTFKRNIAQLETT---IAMMKKDKENIENELLQ 14188
Query: 1310 LKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEE 1131
LK+ Q + E QR + N + + ++ LE K + + K
Sbjct: 14189 LKQTEQ--EREIQRGTDDTSNERENYDEKVTYKTELEDSKEKKKPDRD-SSLKLTDADSA 14245
Query: 1130 RNVVESEHNVLSSEVENLKS----ELKESKDLEGYFLRLFEILLGQHVEVASLDI----E 975
+ E E L ++V+++ ++ ++L +I+L + A D+ E
Sbjct: 14246 KTDGEREAQTLETKVQDVLQLTDYTTQDQEELHDEMENKMKIIL--ELNEAKKDLQKLKE 14303
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEAL---YEYHDYERKNVSGSRAEAMSVLISKS 804
CR AEE+ I++ L RN K+++E L E + + E + ++S
Sbjct: 14304 ECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRS 14363
Query: 803 LGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEK--AEMFETKSREAQQMANK 630
+ + Q +E + + K + E +K + ++ +T + E Q+M +
Sbjct: 14364 VATQWETDVQIQQGQEATETTGHITKK-SEEEISAKKTKQPTVTKLEDTLTSEVQEMRDS 14422
Query: 629 LEEMQQTLSDM 597
L + + ++ M
Sbjct: 14423 LNKEMEDVARM 14433
Score = 62.0 bits (149), Expect = 1e-06
Identities = 117/589 (19%), Positives = 235/589 (39%), Gaps = 54/589 (9%)
Frame = -1
Query: 2108 LQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQ 1929
L++ + + V TER EL + L+ + +++ ++ +EK DLE Q
Sbjct: 12202 LESGKDETDGLTEVHTTERRELEITKLALQSEQQEIEKIRQDIDREKNDLEKYRSDLEKQ 12261
Query: 1928 -------KETVSKELALSVSREQKLASDLKALSEKEESTKNQL--------LIQTEQNK- 1797
K+ + E A + + + K+ E+ ES + QL I E NK
Sbjct: 12262 YEEMEICKQNIENERAELEIDLENIIIETKSKQERLESIEVQLQEKNVQMGTILDELNKR 12321
Query: 1796 QLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCK---LLATKSREVQGQQEGILK---Q 1635
Q EL+ K + +QM +T + +E I L K ++ E+Q Q+E + K Q
Sbjct: 12322 QEELDAIKAKTQREKEQMGHTEELEKDELIAILQKREEIVKRHMEEIQNQREELQKEKDQ 12381
Query: 1634 DINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSL---------KE 1482
N++ EL + G+ +M ++ ++ + + L + + F L E
Sbjct: 12382 FGNMQAELQK----GQLEMEMHQLMLNSERDELNGMRVNLEKQKEEFELMQQNLESRRPE 12437
Query: 1481 EVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQ---HILIE 1311
+L +I + + + L + Q+ + +E R +++ +++ E+ Q L E
Sbjct: 12438 SLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKIKQIEGEIKTKQIEMACLEE 12497
Query: 1310 LKRKNQTLQ--------DESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQ 1155
LK+K Q E Q +EL K ++ + L Q K EL
Sbjct: 12498 LKQKELDEQKNMRECENQELQMRREELAKMKTEIDIERDEIQKLRKQYEKEKCELEQIKP 12557
Query: 1154 KAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIE 975
+ + E+ E +H+ + +++LK E +E +E D++
Sbjct: 12558 DLQKREPEKIDAEVQHDEIHGGIDSLKEEREE-------------------IEKMKADLQ 12598
Query: 974 SCRFAEEKLMRILD-ELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVL-ISKSL 801
+ E + I+ E L + A+++ A+ + KN+ + ++L ++K
Sbjct: 12599 NKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIEAILKVTKKQ 12658
Query: 800 GN--GRANQREFQNKEEDSSGVDLLKNKCTRL--------EFQVQKLSEKAEMFETKSRE 651
N + N+ + K E + +L+ + T L EF + K+ E+ +T R
Sbjct: 12659 KNYLEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKMEEREAERKTIERV 12718
Query: 650 AQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGE 504
+MA + E++++ ++ + E T+ +SE++ E
Sbjct: 12719 MDEMAEEHEKIKKEREELVNMEEEIKKQRRVLEESMNEMTKKKSELQHE 12767
Score = 60.5 bits (145), Expect = 3e-06
Identities = 107/584 (18%), Positives = 246/584 (42%), Gaps = 26/584 (4%)
Frame = -1
Query: 2291 RLYEEEKQHTIELQENFNALRQKNEDI-CLKIE---ANNNLLEQKDN---IIVELSHKLQ 2133
RL EE + Q+ A + + D +K E AN L +Q++ I E+ + +
Sbjct: 6581 RLNEEINIQKVNQQKQATAFQMEKTDFERIKTEIDQANKELADQQEKNKKTITEMQKERE 6640
Query: 2132 ENEEQRSALQNDMQSV-EQMHAVSQTERE--ELNRQLVLLRDDVNHLKEALSMAV----- 1977
EE R+ + ++++ + ++S E E +L ++ + +++ LK + M +
Sbjct: 6641 TLEEMRANISKQVETITNENKSLSSRESELAKLQEDILQQQQEMDELKNTIMMEMCQLDQ 6700
Query: 1976 --DDRAFMEKQLQDLENQKET----VSKELALSVSREQKLASDLKALSEKEESTKNQLLI 1815
D ++K++ DL + +T V +E +++ + + SD+ +L ++E+ + L
Sbjct: 6701 RQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLK 6760
Query: 1814 QTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQ 1635
E+ +E E E L +L + +K E L + ++ +++ + K
Sbjct: 6761 LNEEKDLIEKERELLTKNLDHTDKDKMDMKRELEN-------LKVEKETIKNEKKELEKM 6813
Query: 1634 DINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSL 1455
I+++ + KE D + + + A+ + L++ + F EE L
Sbjct: 6814 KISLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFI--EERLDQTEKK 6871
Query: 1454 RNDAQMVQVALEQ----MQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTL 1287
R + ++ +Q TK E+ + E E+ R + E++ + L ++ N
Sbjct: 6872 RRKTYYTEDLFQEEKTDLQKTKEEINYDRE----EIYRQRTELNKEKETLKQMHTSNLKE 6927
Query: 1286 QDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEH 1107
+ ++ +++ L+ + ++ L+++ R + ++ ++ ++ + +++E
Sbjct: 6928 IENIEKEKEKIQRTWNELDQIRAE---LQNKQRDMDDTTNIMMKEKAELARDLENLQNEK 6984
Query: 1106 NVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL 927
+ L EN++ +KE L+ L+ E L + + E + + L I E+
Sbjct: 6985 DELQKSRENIQKLMKE---LQEERLKTSEALNKERQQFT----EEIKLKNDSLDEIQAEI 7037
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRAN-QREFQNKEEDS 750
R + A + ++ + + + R + S RAN QRE + D
Sbjct: 7038 D--RQKRALVTDKEIITKQMMDLQKTQDVRRQ------SDESDIARANLQRE--RESLDQ 7087
Query: 749 SGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEM 618
V++LK K LE + +L E+ + ET+ + + + E+
Sbjct: 7088 LSVEILKQK-QDLERERDELLEQWRLVETQKMDNENVKQLKTEL 7130
Score = 59.7 bits (143), Expect = 5e-06
Identities = 119/587 (20%), Positives = 244/587 (41%), Gaps = 18/587 (3%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
KE + EE + EL+E Q+N+++ E +LLE++ + +LQ+
Sbjct: 11771 KEYESIIEETNRKRTELEEIEVDQSQQNKNV----ETMKDLLEKERKDTEKEREELQKQA 11826
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQ----LVLLRDDVNHLKEALSMAVDDRAFME 1956
+ + E+M S E ++L Q ++ RDD+ KE + ++ ++
Sbjct: 11827 DDLEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQ 11886
Query: 1955 KQLQDLENQKETVSKELA---LSVSREQK-LASDLKALSEKEESTKNQLLIQTEQNK-QL 1791
K++Q+ +N+ E + EL + + +EQK L L ++E+ + + +++ + K Q
Sbjct: 11887 KEIQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLE---IVRVDYEKHQQ 11943
Query: 1790 ELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDEL 1611
++E ++ ++ +++ + K L+ K E G+LK+++
Sbjct: 11944 QIEEMRVKTKMERDELDQLMAK----------MLMDRKENERSKDMIGLLKKEM------ 11987
Query: 1610 ARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQ 1431
+ K N DA E L K + + K+++ ++ +A V+
Sbjct: 11988 -----------EQTKFNLDAQE------EELKLEKQKIQNEKKDLEMFKAEIKREASEVK 12030
Query: 1430 VALEQM--QDTKS-ELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAK 1260
EQ +DTK+ E E + Q V + E + IQ + E+KR + E + K
Sbjct: 12031 TLKEQQLEKDTKAFEALKEEHLPGQFVQQKGGEFERIQ--IDEVKR----ILSEIHKEKK 12084
Query: 1259 ELWNAKARLNNVMSKNINLESQNRSLKAELHL--QAQKAFQIQEERNVVESEHNVLSSEV 1086
EL K L + + ++S+ S + ++ L A + +++ +V S+ +
Sbjct: 12085 ELERNKQILEHQREALLEIKSKQPSERLDVILVSSATQTSDLEDIPDVSASQGETVEKHT 12144
Query: 1085 ENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMR----ILDELICL 918
+ +K E S E Y + + L Q + E + A+ ++ I D I +
Sbjct: 12145 DIIK-EYTTSIPKEEYEI---DKLKQQGDKKLKSTREDTKMADTEVTTQYKYIPDPSIMM 12200
Query: 917 RNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVD 738
+ E+ K + + L E H ER+ + ++ A Q E Q E+ +D
Sbjct: 12201 KLESGKDETDGLTEVHTTERRELEITKL---------------ALQSEQQEIEKIRQDID 12245
Query: 737 LLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDM 597
KN + ++K E+ E+ + Q + N+ E++ L ++
Sbjct: 12246 REKNDLEKYRSDLEKQYEEMEICK------QNIENERAELEIDLENI 12286
>ref|XP_005159742.1| PREDICTED: titin isoform X5 [Danio rerio]
Length = 15134
Score = 126 bits (317), Expect = 4e-26
Identities = 169/712 (23%), Positives = 304/712 (42%), Gaps = 41/712 (5%)
Frame = -1
Query: 2258 ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQ 2079
+LQ +L + E + L EA N E I +L K +E E+ + Q+D Q VE+
Sbjct: 4260 DLQHKMFSLDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVEE 4319
Query: 2078 MHAVSQTER-------EELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLE----- 1935
M A Q ER EE NR+ ++L + +KE + DR +EK+ DLE
Sbjct: 4320 MTAQIQKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSK 4379
Query: 1934 --NQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGS 1761
KE + K+ + ++ QK DL+ ++EK + + Q EQ KQ + E+++L
Sbjct: 4380 LLRAKENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTE 4439
Query: 1760 LQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQ---EGILKQDINIEDELARTK-EV 1593
+Q Q E L+ E I L + E+ QQ I++ N +L + K E
Sbjct: 4440 IQNLQQE---LEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEET 4496
Query: 1592 GRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINS--------LRNDAQM 1437
+M+K D + E L MK L+++VL + S L +A
Sbjct: 4497 EEQKQEMEKEKHDFDQSRKSLDEDLKMMK-----LQKQVLEDEKSKLEQMKIELEREAVE 4551
Query: 1436 VQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQ-TLQD--ESQRN 1266
++ E++Q+ + L E +E L E +L E+K N+ TL D + N
Sbjct: 4552 IRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKSN 4611
Query: 1265 AKEL-WNAKARLNNVMSKNINL---ESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVL 1098
+E+ N + +V +K NL E + R L+AE+H Q + +I++E+ +ESE +
Sbjct: 4612 LEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQR---EIEKEKINIESERAAI 4668
Query: 1097 SSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICL 918
+VE+L+ ++ I L + E LD E+ +E L ++ EL
Sbjct: 4669 IKDVEDLQHKI---------------ICLDRDAESLKLDREAFENEKEVLKQMKTELERE 4713
Query: 917 RNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVD 738
+E K+K E HD + R E M+ I K ++ E N E+++ D
Sbjct: 4714 ADEIEKIKLET---QHDRQ-------RVEEMAAQIQK-------DRDEINNLIEETNRKD 4756
Query: 737 LLKNKCTR-LEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXI 561
++ N+ R +E +++ + +M E + + ++ ++L ++++ L
Sbjct: 4757 MVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQ---------KEN 4807
Query: 560 RVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPL------IQXXXXX 399
+ ++KE L + KH+E ++ + D+ T + ++
Sbjct: 4808 TLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEI 4867
Query: 398 XXXXXXKIDTRTSETQEIDTLMDDNRKYW-NRVSHFTKQTQSLQNSVQELQQ 246
++D R SE + T M+D + N K + ++ QE+++
Sbjct: 4868 IMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEK 4919
Score = 101 bits (251), Expect = 2e-18
Identities = 162/831 (19%), Positives = 370/831 (44%), Gaps = 70/831 (8%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLK--IEANNNLLEQKDNIIVELSHKLQE 2130
+E++ +++ +Q E + +QK +D+ + ++ + LE+ ++E+ K +
Sbjct: 10336 EEINHKWKQLQQRIDEFDAQVS--KQKEQDLPKEKGMKEDRKSLEETKANVIEMKTKAEP 10393
Query: 2129 NE---EQRSALQNDMQSVEQMHAVSQTEREELNR---QLVLLRDDVNHLKEALSMAVDDR 1968
E E+ + + + E++ + +TER+EL + +L +R +++H ++ L+ D
Sbjct: 10394 EEIKKEKEKENEEEEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQKKLN---DYM 10450
Query: 1967 AFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALS------EKEESTKNQLLIQTE 1806
+E++ +DLE K + K+ +L + ++ + EK + +L+++ E
Sbjct: 10451 KMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVEVE 10510
Query: 1805 -QNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDI 1629
Q K ++L+ E+L Q E LL K+ + + + E++ ++E + + +I
Sbjct: 10511 EQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKKVDEEIKKERETLREMEI 10570
Query: 1628 NIEDELARTK----EVGRSATDMKKVNSDAGAKVSGILEMLLPMK---DDVFSLKEEVLG 1470
+++ E + E R D++K+++D I E L +K D + +EE+
Sbjct: 10571 HLKKEKEELRSIIEETQRRKEDLEKMSTD-------INEQKLHLKNQRDLLEQEREEINH 10623
Query: 1469 NINSLRN-----DAQM-----------VQVALEQMQDTKSELF-AEAEIRAQEVLRLQAE 1341
+ L+ DAQ+ ++ + +++TK+ + + + QE+++ + E
Sbjct: 10624 EMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEE 10683
Query: 1340 VDAIQ-HILIELKRKN-QTLQDESQRNAKELWNAKARLNNVMSKNINLESQN-RSLKAEL 1170
D + +++E++R+ ++ E +R E+ + + +LN+ K I E ++ +K+E+
Sbjct: 10684 EDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLND-DKKIIEQEKEDLEKMKSEI 10742
Query: 1169 HLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDL-EGYFLRLFEILLGQHVEV 993
Q Q Q++EER+ E ++ + +++E + +++ SK++ + +++ E ++
Sbjct: 10743 MTQRQ---QMEEERS--ELDNKIKQTDLE--RHDIENSKEIVQKLMVKVEEQRKDIRLQK 10795
Query: 992 ASLDIESCRFAEEKLMRILDELICLRNENAKLK---------NEALYEYHDYERKNVSGS 840
LDIE + A+E+ + ++ L+NEN ++K E L E + RK
Sbjct: 10796 EELDIERQKIADEQGL-VVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEM 10854
Query: 839 RA-------------EAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQV 699
R+ E MS ++K NQR+ +E + + +K T+L+ ++
Sbjct: 10855 RSVIEETQRRKKEDLEKMSTDVNKQ-NQDLMNQRDLLKQEREE-----INHKWTQLQQRI 10908
Query: 698 Q----KLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENT 531
++S++ E TK ++ ++ LEE + + +M + + ++E
Sbjct: 10909 DEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKE-EEEVM 10967
Query: 530 RLRSEM-KGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSET 354
R + EM K EL +S R S I DD +I+ +I + +
Sbjct: 10968 RAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQM 11027
Query: 353 QEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSI 174
+E + +D N++ + ++NS + +Q+ M +
Sbjct: 11028 EEERSELD------NKIKQTDLERHDIENSKEIVQKL-------------------MVEV 11062
Query: 173 EKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEEV 21
E+Q K++ + +L ++ + G N N E+ ++DEE+
Sbjct: 11063 EEQRKDIRLQKEELDIERQKIADEQ--GLVVQNKAKLQNENERIKEMDEEI 11111
Score = 100 bits (250), Expect = 2e-18
Identities = 148/763 (19%), Positives = 321/763 (42%), Gaps = 12/763 (1%)
Frame = -1
Query: 2276 EKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQND 2097
E QH + E A QK+ D KI NNL+E+ + + L+ K ++ E++ ++Q+D
Sbjct: 5596 ETQHDRQRVEEMTAQIQKDRD---KI---NNLIEETNRKDMVLNEKNRDIEKKIKSIQSD 5649
Query: 2096 MQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETV 1917
+E+ + + E+ +L +++D+ KE + A ++K+ +DLE E +
Sbjct: 5650 KDMLEK----EKHDLEKTRSELYKVKEDLEKQKE------NTLAQIQKEREDLEKMNENI 5699
Query: 1916 SKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQME- 1740
++E+ +E+++ L + + +N +Q E K+ E+ I K L +Q E
Sbjct: 5700 TREMHEIKHQEEQMNQKQDELDQLKTEIQN---LQQELEKEKEI-IMKARSQLDRRQSEL 5755
Query: 1739 ---NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMK 1569
T + D E + + K L E++ Q++ + K+ N++ E + K
Sbjct: 5756 DKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQK 5815
Query: 1568 KVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELF 1389
+V + K+ + L DD+ +KEE +N Q+++ E+++ + ++
Sbjct: 5816 QVIEEEKNKLEQMKIELEREADDIRKIKEET-------QNKRQILEKMAEELKKERKDVA 5868
Query: 1388 AEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNI 1209
AE +E L A + + +L+++ L++ + +K+ + + + + +
Sbjct: 5869 HLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLRED 5928
Query: 1208 NLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLR 1029
LE L+AE+H Q + + E++ +E E + +VE+L+S++
Sbjct: 5929 ELE----QLQAEIHKQQS---ETEIEKSNIERERAAIIKDVEDLQSKI------------ 5969
Query: 1028 LFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNV 849
I L + E LD E+ +E+L ++ EL +E K+K E +ER+ V
Sbjct: 5970 ---ISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLET-----QHERQRV 6021
Query: 848 SGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMF 669
A+ M + ++ + + K+E D + L+ ++ + + ++
Sbjct: 6022 EEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVL 6081
Query: 668 ETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRV-RSLKKENTRLRSEMKGELTPS 492
E + + +QM LE +S + ++ +LK+E L E+K
Sbjct: 6082 EEEKNKLEQMKIGLEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIK------ 6135
Query: 491 RSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYW 312
R+ + +I + +E +Q + R + +++I+ + ++ K
Sbjct: 6136 -----RKNQVLDKIKVANESTLADLQKEKRILE------EMRENISKQIEDIENEKEKSK 6184
Query: 311 NRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQL 132
R K +Q E+ + + M ++K+ +++ + + ++
Sbjct: 6185 LREDELKKLQTEVQKQQSEIDMEKTNIESERAAMIREKQNM-MTELKKKSEDVEMQMKEI 6243
Query: 131 VE-----HNTR--LKKDVKFGFAWANSMHDLNGQEQKLKVDEE 24
+ HN R LKKDV+ + + + LK+D+E
Sbjct: 6244 LTEKELLHNDRNLLKKDVE---DLQQKLMSIERDSESLKLDKE 6283
Score = 98.2 bits (243), Expect = 1e-17
Identities = 169/821 (20%), Positives = 350/821 (42%), Gaps = 72/821 (8%)
Frame = -1
Query: 2282 EEEKQHTI-ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
E++K++T+ ++Q+ L + NE+I ++ + EQ ++ K E ++ ++ +
Sbjct: 5675 EKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQ-------MNQKQDELDQLKTEI 5727
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
QN Q +E+ + R +L+R+ L ++ + + ++R ++K +++E QK
Sbjct: 5728 QNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQK 5787
Query: 1925 ETVSKELALSVSREQKLASDLKALS------EKEESTKNQLLIQTE-------------Q 1803
+ + KE + L DLK + E+E++ Q+ I+ E Q
Sbjct: 5788 QEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQ 5847
Query: 1802 NKQ--LELEIEKL--------YGSLQMKQMENTL--LKDGNEKIYDLCKLLATKSREVQG 1659
NK+ LE E+L + + K+ +N+L +K NE + L KS ++
Sbjct: 5848 NKRQILEKMAEELKKERKDVAHLAEDTKREKNSLDEMKVANES--SMADLQKEKS-NLEE 5904
Query: 1658 QQEGILKQDINIEDE----LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFS 1491
+E I KQ +IE E R E+ + ++ K S+ + S I + DV
Sbjct: 5905 MKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVED 5964
Query: 1490 LKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIE 1311
L+ +++ SL DA+ +++ E ++ K EL Q L+ E D I+ I +E
Sbjct: 5965 LQSKII----SLDRDAESLKLDREAFENEKEEL-------KQMKTELEREADEIEKIKLE 6013
Query: 1310 LKRKNQTLQDESQRNAKELWNAKARL--NNVM---------SKNINLESQNRSLKAELHL 1164
+ + Q +++ + + + N + +L N VM K +++ +SL +L +
Sbjct: 6014 TQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKM 6073
Query: 1163 QAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASL 984
+ ++EE+N +E L E + + S++KE E L L + E +
Sbjct: 6074 MKAQKQVLEEEKNKLEQMKIGLEREADEI-SKIKEETQNERQNLEKMANALKEEREYLAE 6132
Query: 983 DIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKS 804
+I ++ ++LD++ K+ NE+ E++ + E M ISK
Sbjct: 6133 EI-------KRKNQVLDKI--------KVANESTLADLQKEKRIL-----EEMRENISKQ 6172
Query: 803 LGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETK--------SREA 648
+ + +N++E S L +++ +L+ +VQK + +M +T RE
Sbjct: 6173 I-------EDIENEKEKSK---LREDELKKLQTEVQKQQSEIDMEKTNIESERAAMIREK 6222
Query: 647 QQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRS-LKKENTRLRSEMKGELTPSRSFKHRE 471
Q M +L++ + + R+ LKK+ L+ ++ S S K +
Sbjct: 6223 QNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIERDSESLKLDK 6282
Query: 470 GSFIKEINIGDEDDTPL------IQXXXXXXXXXXXKIDTRTS----ETQEIDTLMDDNR 321
+F E + T L I+ +++ +T+ E +EI+TL+++ +
Sbjct: 6283 EAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIK 6342
Query: 320 KYWNRV----SHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDM--NSIEKQLK 159
K + + + K+ +++++ +L++ I N++EK K
Sbjct: 6343 KKRDIIDESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQQKRNALEKMSK 6402
Query: 158 ELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLK 36
E++ M+L + KK+++ MH ++Q+ K
Sbjct: 6403 EISRDRMKLEDE----KKEIQLAREELERMHGDMQRQQEAK 6439
Score = 97.1 bits (240), Expect = 3e-17
Identities = 121/592 (20%), Positives = 267/592 (45%), Gaps = 29/592 (4%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQ----KDNIIVELSHKLQ 2133
E+ ++ EE + L++ AL+++ ED+ + + NN +L++ ++ + ++ +
Sbjct: 4551 EIRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKS 4610
Query: 2132 ENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK 1953
EE R + + VE + +EL + + +++ +RA + K
Sbjct: 4611 NLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIK 4670
Query: 1952 QLQDLENQKETVSKEL-ALSVSR-----EQKLASDLKALSEKEESTKNQLLIQTEQNKQL 1791
++DL+++ + ++ +L + R E+++ +K E+E ++ ++T+ ++Q
Sbjct: 4671 DVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIKLETQHDRQ- 4729
Query: 1790 ELEIEKLYGSLQMKQME-NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDE 1614
+E++ +Q + E N L+++ N K D+ +L K+R+++ + + I +D
Sbjct: 4730 --RVEEMAAQIQKDRDEINNLIEETNRK--DM--VLNEKNRDIEEKIKSIQSD----KDM 4779
Query: 1613 LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
L + K D++K S+ L +K+D+ KE L I R D
Sbjct: 4780 LEKEKH------DLEKTRSE-----------LYKVKEDLEKQKENTLAEIQKERED---- 4818
Query: 1433 QVALEQMQDTKSELFAEAEIRAQEVLRLQAEVD----AIQHILIEL-KRKNQTLQDESQR 1269
LE+M + + E + + +++ + Q E+D IQ++ EL K K ++D SQ
Sbjct: 4819 ---LEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQL 4875
Query: 1268 NAK--ELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLS 1095
+ + EL + +N++M N Q K E+ Q Q ++++ER+ ++ L
Sbjct: 4876 DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQ---EMEKERDNMDQSRKSLD 4932
Query: 1094 SEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLR 915
+ + +K + K+ + E L +I L + + S E + ++L ++ +ELI +
Sbjct: 4933 EDQKKMKLQ-KQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREK 4991
Query: 914 NENAKLKNEALYEYHDYERKNVSGSRAEA---MSVLISKSLGNGRANQREFQNKEEDSSG 744
A L + E + V+ + A I + + + +E+ + E++ S
Sbjct: 4992 ESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENISKLKEYIDNEKEKS- 5050
Query: 743 VDLLKNKCTRLEFQVQKLSEKAEMFETK--------SREAQQMANKLEEMQQ 612
L +++ +L+ +VQK K +M +T RE Q M +L++ +
Sbjct: 5051 -KLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKKSE 5101
Score = 96.7 bits (239), Expect = 4e-17
Identities = 128/572 (22%), Positives = 261/572 (45%), Gaps = 11/572 (1%)
Frame = -1
Query: 2282 EEEKQHTIELQEN-FNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
+E+ HT EL+++ A+ QK E+I + +E+ N EL + + ++ L
Sbjct: 12336 KEQMGHTEELEKDELIAILQKREEIVKRH------MEEIQNQREELQKEKDQFGNMQAEL 12389
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
Q +E + +ER+ELN V L E + ++ R E L+D+ +K
Sbjct: 12390 QKGQLEMEMHQLMLNSERDELNGMRVNLEKQKEEF-ELMQQNLESRR-PESLLEDILKEK 12447
Query: 1925 ETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQ 1746
+ V +E+A +S+EQ E +N I +E K++E +I+++ G ++ KQ
Sbjct: 12448 KRV-EEMAAQLSKEQ-------------EEFRN---IMSETIKRME-KIKQIEGEIKTKQ 12489
Query: 1745 MENTLLKDGNEKIYDLCK-LLATKSREVQGQQEGI--LKQDINIE-DELAR-TKEVGRSA 1581
+E L++ +K D K + +++E+Q ++E + +K +I+IE DE+ + K+ +
Sbjct: 12490 IEMACLEELKQKELDEQKNMRECENQELQMRREELAKMKTEIDIERDEIQKLRKQYEKEK 12549
Query: 1580 TDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTK 1401
+++++ D L+ P K D +E+ G I+SL+ + + ++ +Q+
Sbjct: 12550 CELEQIKPD--------LQKREPEKIDAEVQHDEIHGGIDSLKEEREEIEKMKADLQNKL 12601
Query: 1400 SELFAEAEIRAQEVLRLQAEVDAIQHILIELK--RKNQTLQDESQRNAKELWNAKARLNN 1227
E +I +E L+ + I+ + +E + ++ LQDE + L K + N
Sbjct: 12602 REAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIEAILKVTKKQKNY 12661
Query: 1226 VMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDL 1047
+ N NL + L+ + ++ ++ ++ E H S++E ++E K +
Sbjct: 12662 LEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEFH---MSKMEEREAERKTIE-- 12716
Query: 1046 EGYFLRLFEILLGQHVEVASLDIESCRFAEE--KLMRILDELICLRNENAKLKNEALYEY 873
R+ + + +H ++ E EE K R+L+E + NE K K+E +E
Sbjct: 12717 -----RVMDEMAEEHEKIKKEREELVNMEEEIKKQRRVLEESM---NEMTKKKSELQHER 12768
Query: 872 HD-YERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQ 696
+ Y++K + + +I+ +R Q+KE++ +LK + +
Sbjct: 12769 SELYKQK-------QQLEDMIASESKRDVDTERSRQDKEDE----QILKREREEIADMKD 12817
Query: 695 KLSEKAEMFETKSREAQQMANKLEEMQQTLSD 600
+L ++ E ET + +E+MQ L+D
Sbjct: 12818 QLLKEKEDVETTKERINREKEHIEKMQSQLND 12849
Score = 95.9 bits (237), Expect = 7e-17
Identities = 121/615 (19%), Positives = 259/615 (42%), Gaps = 8/615 (1%)
Frame = -1
Query: 2291 RLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRS 2112
R+ E + Q + + +E+ ++ ED E N+LE K E K +E EE+
Sbjct: 11462 RIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQ 11521
Query: 2111 ALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLEN 1932
++ ++ + + E E++ QL +R +++H ++ L+ DD+ +E++ +DLE
Sbjct: 11522 EMRVKVE-------MERKEIEQIKSQLERVRSEMDHEQKKLN---DDKKMIEQEKEDLEK 11571
Query: 1931 QKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQM 1752
K + K+ +L +K ++ +N E ++L +E+EK +Q
Sbjct: 11572 MKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENS----KEIVEKLMVEVEKQKHEIQF 11627
Query: 1751 KQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDM 1572
++ E L +KI D LL E Q + E I + D I+ E KE+ +
Sbjct: 11628 QKEE---LDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNLQKE 11684
Query: 1571 KKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSEL 1392
K+ + E L M D+ K++++ + L+ + + + L Q+Q E
Sbjct: 11685 KEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEF 11744
Query: 1391 FAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKN 1212
+ I + + E+D L + ++ +++ +E+ R EL +
Sbjct: 11745 ETTSNILVTTKMEEKTEMD---EKLQQAIKEYESIIEETNRKRTELEEIE---------- 11791
Query: 1211 INLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFL 1032
++ QN++++ L +++ER E E L + ++L+ ++ E D E
Sbjct: 11792 VDQSQQNKNVETMKDL-------LEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSK 11844
Query: 1031 RLFEI---LLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYE 861
R + LL Q + +E +M+ +EL L+ E KNE + E
Sbjct: 11845 RSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKEIQNQKNEMEEIKCELE 11904
Query: 860 RKNVSGSRAEAMSVLISKSLGNGRANQREFQ----NKEEDSSGVDLLKNKCTRLEFQVQK 693
K + + + + +SL ++ + + E+ ++ ++ K ++ +
Sbjct: 11905 TKRIEIIKEQKR---LEESLNTVNEERQYLEIVRVDYEKHQQQIEEMRVKTKMERDELDQ 11961
Query: 692 LSEKAEMFETKSREAQQMANKLE-EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSE 516
L K M ++ ++ M L+ EM+QT ++ ++++ KK+ ++E
Sbjct: 11962 LMAKMLMDRKENERSKDMIGLLKKEMEQTKFNLDAQEEELKLEKQKIQNEKKDLEMFKAE 12021
Query: 515 MKGELTPSRSFKHRE 471
+K E + ++ K ++
Sbjct: 12022 IKREASEVKTLKEQQ 12036
Score = 94.7 bits (234), Expect = 2e-16
Identities = 148/745 (19%), Positives = 307/745 (41%), Gaps = 60/745 (8%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQ------ENFNALRQKNED-----ICLKIEANNN-----LLEQK 2169
E+ R EE ++ + LQ EN A Q+ ED I +KI+ L ++
Sbjct: 8911 EMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQLDKET 8970
Query: 2168 DNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEAL 1989
+ E+ K+++ E + + ++ Q +E + + E++EL ++ L D + L
Sbjct: 8971 KRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREK 9030
Query: 1988 SMAVDDR---AFMEKQLQDLENQKETVSKELALSVS----------REQKLASDLKALSE 1848
++R ++ QL+DL + E V ++L L S ++Q+L + ++
Sbjct: 9031 QETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENK 9090
Query: 1847 KEESTKNQLLIQTEQNKQ-LELEIEKLYGSL-QMKQMENTL--LKDGNEKI--------Y 1704
KE+ + Q +TEQ KQ LE+ K+ +M + L KD EKI +
Sbjct: 9091 KEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDELEKIAYKTNKERH 9150
Query: 1703 DLCKLLATKSREVQG-QQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAK---VS 1536
++ ++ A ++Q +Q+G + QD E + + R ++K N++ + ++
Sbjct: 9151 EVEQMQAELHSQIQAIEQQGQIMQDKQNHLE-EKELSIQRKEEEIKIGNTEFQIEQEHLN 9209
Query: 1535 GILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSEL--FAEAEIRAQE 1362
+LE + D+ ++ ++ N D ++++ ++++ K +L + E + E
Sbjct: 9210 NVLEETNKRQHDLEVMRADIELNKQKNNKDFELLEKIRSELENEKYDLQIWTEQQKHLVE 9269
Query: 1361 V--LRLQAEVDAIQHILIELKRKNQTLQDES---QRNAKELWNAKARLNNVMSKNINLES 1197
V L+ E + ++ + IEL+ K + + E R E+ K ++
Sbjct: 9270 VQLQELEKEKERLEKMEIELQSKREQTEKEKADLNRVNAEIQREKQVIDKKRHMTNRAME 9329
Query: 1196 QNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEI 1017
+ ++K EL + +K IQ E+ +E E ++ E ENL L+E K +
Sbjct: 9330 ELETIKTELKERQEK---IQTEQEKLEEEKLLVQIEAENLNKVLEEIKRQQ--------- 9377
Query: 1016 LLGQHVEVASLDI----ESCRFAEEKLMR---ILDELICLRNENAKLKNEALYEYHDYER 858
+ +E++ D+ E C A E+ R ++E I NENAK + ER
Sbjct: 9378 ---EKLEISEADLKVMKEQCENAREETERKKCDIEEQI-QNNENAK-------HLLEQER 9426
Query: 857 KNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKA 678
K++ + E + + +K LL+ K + Q L ++
Sbjct: 9427 KDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEKEK 9486
Query: 677 EMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELT 498
E K + + N+++ + + ++ + + +E+ R +E KG+L
Sbjct: 9487 EDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGDLE 9546
Query: 497 PSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRK 318
R+ ++ I+E+ + + + + +ID + +++ R
Sbjct: 9547 IMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKERN 9606
Query: 317 YWNRV-SHFTKQTQSLQNSVQELQQ 246
++ S Q Q +++ EL Q
Sbjct: 9607 DLEKMKSELMTQRQQMEDERSELDQ 9631
Score = 94.0 bits (232), Expect = 3e-16
Identities = 135/605 (22%), Positives = 286/605 (47%), Gaps = 41/605 (6%)
Frame = -1
Query: 2291 RLYEEEKQHTIELQENF-NALRQKNEDICLKIEANNNLLEQKDNIIVE---LSHKLQENE 2124
R+ E + Q + +E+ N + + E CL+ E N ++E K +E ++ K++E +
Sbjct: 9779 RIDEFDAQVRKQKEEDLTNQKKMEEERKCLE-EVNGKIIEMKTKAELEHHEINQKIEELQ 9837
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNR---QLVLLRDDVNH----LKEALSMAVDDRA 1965
+ + + + E M + ERE+L++ +LV + +V+H L + + M ++
Sbjct: 9838 TLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKE 9897
Query: 1964 FMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLEL 1785
+EK ++ QK+ + KE + ++ Q+ + + + +E + + EQ +++L
Sbjct: 9898 DLEKMKSEIMTQKQEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRHEIQL 9957
Query: 1784 EIEKLYGSLQMKQMENTL-------LKDGNEKIYDLCKLLATKSREVQGQQEGILKQD-- 1632
+ E+L Q E L L++ NE+I ++ +++ K RE + E L+++
Sbjct: 9958 QKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEVI-KKERETLKEMEAHLEKEKE 10016
Query: 1631 --INIEDELARTKE-VGRSATDMKKVNSDAGAKVSGILEM----------LLPMKDDVFS 1491
+I +E R KE + + +TD+K+ N D K +LE L + D F
Sbjct: 10017 EMKSITEETRRQKEDLEKMSTDIKEQNQDL-MKQRDLLEQEKEDINHEWTQLQQRIDEFD 10075
Query: 1490 L-----KEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQ 1326
KEE L ++ + + +LE+ + E+ +AE+ + + + E +
Sbjct: 10076 AQVSKQKEEDLTKQKEMKEERK----SLEETKARIIEMKTKAELEDIKKEKEKEEEEEEM 10131
Query: 1325 HILIELKRKN-QTLQDESQRNAKELWNAKARLNNVMSKNINLESQN-RSLKAELHLQAQK 1152
+ +E+ K ++ E +R E+ + + +LN+ K I E QN +K+E+ Q Q
Sbjct: 10132 RVKVEMDGKELDRIKSELKRERSEIDHEQKKLND-DKKIIEQEKQNLEKMKSEIMKQRQ- 10189
Query: 1151 AFQIQEERNVVESEHNVLSSEVENLKSELKESKDL-EGYFLRLFEILLGQHVEVASLDIE 975
Q++EER+ E E+ + + +E K +++ SK++ + + + E + LDIE
Sbjct: 10190 --QMEEERS--ELENKIKQTYIE--KCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIE 10243
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGN 795
+ A+E+ + I ++ L+NEN +++N L E ER+ + + M + K
Sbjct: 10244 RQKIADEQDLLIQNKSE-LQNENERIRN--LNEIIKKERETL-----KEMEAHLEKKKEE 10295
Query: 794 GRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQ 615
++ E + +ED L+ T + Q + L + ++ E +E +++ +K +++Q
Sbjct: 10296 IKSVSEETRRLKED------LEKMSTDVNKQNKDLMNQRDLLE---QEREEINHKWKQLQ 10346
Query: 614 QTLSD 600
Q + +
Sbjct: 10347 QRIDE 10351
Score = 93.2 bits (230), Expect = 4e-16
Identities = 143/645 (22%), Positives = 276/645 (42%), Gaps = 45/645 (6%)
Frame = -1
Query: 2276 EKQHTIELQENFNALRQ-KNEDICLKIEANNNLLEQKDNIIV-ELSHKLQENEEQRSALQ 2103
++ I+ ++ LR+ K + + +I ++ K +II E + ++N++ + L
Sbjct: 3562 KQNEMIDSEKKKMILREDKLQQMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMTELT 3621
Query: 2102 NDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKE 1923
+ VE TE+E L LL+ DV +L++ L + D +++ + LEN+KE
Sbjct: 3622 KQSEDVEIQMKEVLTEKELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKE 3681
Query: 1922 TVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQ--------NKQLELEIEKL- 1770
V K++ + E + +K ++ E ++ Q ++ N + EI +
Sbjct: 3682 -VLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIK 3740
Query: 1769 YGSLQMKQMENTL------LKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELA 1608
Y QMKQ ++ L +++ +++ +++ E+ +Q + KQ N+ D +
Sbjct: 3741 YQEKQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLKQSELDKQQTNMNDIIE 3800
Query: 1607 RTK-----------EVGRSATDMKKVNSDAGAKVSGILEMLLPMK--DDVFSLKEEVLGN 1467
K E+ +++K D + + E L MK VF ++ L
Sbjct: 3801 TMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVFEEEKNKLEQ 3860
Query: 1466 IN-SLRNDAQMVQVALEQMQDTKSEL---FAEAEIRAQEVLRLQAEVDAIQHILIELKRK 1299
+ L +A ++ E++Q+ + L E + + L + Q IL E+K
Sbjct: 3861 MKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVA 3920
Query: 1298 NQTLQDESQR---NAKEL-WNAKARLNNVMSKNINL---ESQNRSLKAELHLQAQKAFQI 1140
N++L E Q+ N +E+ N + +V +K NL E + L+AE+H Q + +I
Sbjct: 3921 NESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLREDELGQLQAEIHKQQR---EI 3977
Query: 1139 QEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFA 960
++E++ +ESE + VE+L+ ++ I L + E LD E+
Sbjct: 3978 EKEKSNIESERAAIIKIVEDLQHKI---------------ISLDRDAESLKLDREAFENE 4022
Query: 959 EEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQ 780
E L ++ EL +E K+K E +E R E M+ +++ N R
Sbjct: 4023 REVLKQMKTELEREADEIEKIKLETQHE----------RQRVEEMTADFMETMNNERKQL 4072
Query: 779 REFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSD 600
+NKEE ++ + ++ + L + +M + + + ++ NKLE+M+ L
Sbjct: 4073 N--KNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIELE- 4129
Query: 599 MXXXXXXXXXXXIRVRSLKKE--NTRLRSE-MKGELTPSR-SFKH 477
+R +K+E N R R E M EL + SF H
Sbjct: 4130 ---------KEADEIRKIKEETQNERQRLEKMTEELKKEKESFTH 4165
Score = 92.4 bits (228), Expect = 8e-16
Identities = 119/631 (18%), Positives = 280/631 (44%), Gaps = 68/631 (10%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE- 2124
E + + +Q E+++ N L +K EDI + + + + +E+ + E E
Sbjct: 294 ETQKAKDLMEQMKAEIEDEKNELEKKKEDIKRQRDQFEQIKLDLQQVKMEMEQRWHETEK 353
Query: 2123 ---EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFM-- 1959
EQR+ +Q + + ++ + Q REE+ R + + + + + A+++ +
Sbjct: 354 EGLEQRAVIQREKEQLKYLQDEIQRVREEVERNREFSKQEHARISQLRAQALEENNLIEN 413
Query: 1958 --------EKQLQDLENQKETVSKELALS---VSRE----QKLASDLKALSEKEESTKNQ 1824
EK L++++++ E +EL ++ V +E ++ D+++ E ++
Sbjct: 414 KWHDILRKEKDLEEMKHEIERGREELVMNGELVKKEWEKIEQAKVDIQSHMISMEGRVDE 473
Query: 1823 LLIQTEQNKQLELEIEKLYGSLQMKQMENT--LLKDGNEKIYDLCKLLATKSREVQGQQE 1650
+ +TE+ K ++ E+++ +L+ KQ ++T ++ K Y+ + T+ E + + +
Sbjct: 474 IKRETERLKHIKTEMQRDKDALE-KQKDDTRKAKEEAERKRYE----IVTEELEHRARLQ 528
Query: 1649 GILKQDINIEDELARTKEVGRSATDMKK-------------------VNSDAGA---KVS 1536
+ NI E+ R +V ++ +K VN++ A +++
Sbjct: 529 RERDELENIRAEMQRVNDVEKAKILKEKEESIRIREEARQERETTELVNAEIKAEKERLN 588
Query: 1535 GILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVL 1356
E +L + ++ +K E L + N + E+M+ K+E+ + E ++V
Sbjct: 589 QRQEEMLRERQEIERIKHETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVE 648
Query: 1355 RLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNR---- 1188
+Q + ++ +EL+ + + L+ + ++E+ A+ N ++ +ES+ R
Sbjct: 649 EIQKTKEQMEEAKVELEEEREDLERKRDLVSREIEQAEFLRNEILRVKEEMESRWRETET 708
Query: 1187 ---SLKAELHLQAQKAFQIQEE-----RNVVESEHNVL--SSEVENLKSELKESKD---L 1047
L+A+ + ++ +++EE +N+ ES+ ++ ++ LK E++E K +
Sbjct: 709 EEVELRAKTQHELERLEKLREETERSQKNIEESKIELMLWKESLDKLKGEMEEDKHVVIM 768
Query: 1046 EGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNE----NAKLKNEALY 879
+ + E L +E ++ + EK+ LDE+ +RNE +A++++
Sbjct: 769 QMNEAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQHAEMEDWFRV 828
Query: 878 EYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQV 699
+ E N++ +L+ K + + +R ++ E D ++ K LE Q+
Sbjct: 829 VNKEKEEANLAKLAVHEAEMLLKKQM--EESEKRRYEMITEALEQRDEIQKKAEELE-QI 885
Query: 698 QKLSEKAEMFETKSR--EAQQMANKLEEMQQ 612
K ++A K R E + + LE+ QQ
Sbjct: 886 NKEIQRARQELEKMRYFEKESLQKMLEDTQQ 916
Score = 92.0 bits (227), Expect = 1e-15
Identities = 142/718 (19%), Positives = 312/718 (43%), Gaps = 33/718 (4%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEAN----NNLLEQKDNIIVELSHKLQ 2133
E+ R +E ++ +E Q + RQ+ E++ +I+ + NNL+E+ + + L+ K +
Sbjct: 4709 ELEREADEIEKIKLETQHD----RQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNR 4764
Query: 2132 ENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK 1953
+ EE+ ++Q+D +E+ + + E+ +L +++D+ KE + A ++K
Sbjct: 4765 DIEEKIKSIQSDKDMLEK----EKHDLEKTRSELYKVKEDLEKQKE------NTLAEIQK 4814
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEK 1773
+ +DLE E +++E+ +E+++ L + + +N +Q E K+ E+ I K
Sbjct: 4815 EREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQN---LQQELEKEKEI-IMK 4870
Query: 1772 LYGSLQMKQME----NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 1605
L ++Q E T + D E + + K L E++ Q++ + K+ N++
Sbjct: 4871 DRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKS 4930
Query: 1604 TKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVA 1425
E + K++ + K+ + L D++ +KEE +N Q ++
Sbjct: 4931 LDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEET-------QNKRQRLEKM 4983
Query: 1424 LEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNA 1245
E++ K L AE E L A + + +L+R+ L +E + N +L
Sbjct: 4984 TEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSIL-EEMRENISKL--- 5039
Query: 1244 KARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL 1065
K ++N K+ E + + L+ E+ Q K I E+ +ESE + E +N+ +EL
Sbjct: 5040 KEYIDNEKEKSKLREDELKKLQTEVQKQQSK---IDMEKTNIESERAAMIREKQNMMTEL 5096
Query: 1064 -KESKDLEGYFLRLFEILLGQHV-----EVASLDIESCR----FAEEKLMRILDELICLR 915
K+S+D+E +++ EIL + + ++ + D+E+ + E R+ +
Sbjct: 5097 KKKSEDVE---IQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFE 5153
Query: 914 NEN---AKLKNEALYEYHDYERKNV----SGSRAEAMSVLISKSLGNGRANQREFQNKEE 756
NE ++K + + + E+ + R E M+ I K + + N E
Sbjct: 5154 NEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQK-------ERDKINNLIE 5206
Query: 755 DSSGVDLLKNKCTR-LEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXX 579
+++ D++ N+ R +E +++ + +M E + ++ ++L ++++ L
Sbjct: 5207 ETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQ------ 5260
Query: 578 XXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPL------I 417
+ ++KE + + KH+E ++ + D+ T + +
Sbjct: 5261 ---KENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQEL 5317
Query: 416 QXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYW-NRVSHFTKQTQSLQNSVQELQQ 246
+ + D R SE + T M+D + N K + ++ QE+++
Sbjct: 5318 EKEKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEK 5375
Score = 91.7 bits (226), Expect = 1e-15
Identities = 146/693 (21%), Positives = 299/693 (43%), Gaps = 77/693 (11%)
Frame = -1
Query: 2282 EEEKQHTI-ELQENFNALRQKNEDICLKI-------EANNNLLEQKDNIIVELSHKLQEN 2127
E++K++T+ E+Q+ L + NE+I ++ E N ++ D + E+ + QE
Sbjct: 4802 EKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQEL 4861
Query: 2126 EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL 1947
E+++ + D ++ + EL++Q + D + +K D+ ME+Q
Sbjct: 4862 EKEKEIIMKDRSQLD-------LRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQK 4914
Query: 1946 QDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLY 1767
Q++E +++ + + S+ +QK K + E+E++ Q+ I+ E+ EI K+
Sbjct: 4915 QEMEKERDNMDQS-RKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREAD---EISKIK 4970
Query: 1766 GSLQ-----MKQMENTLLKD------------GNEKIYDLCKL-----LATKSRE---VQ 1662
Q +++M L+++ +KI D K+ +A RE ++
Sbjct: 4971 EETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILE 5030
Query: 1661 GQQEGI--LKQDINIEDELARTKE-----------VGRSATDMKKVN--SDAGAKVSGIL 1527
+E I LK+ I+ E E ++ +E +S DM+K N S+ A +
Sbjct: 5031 EMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQ 5090
Query: 1526 EMLLPMK---DDVFSLKEEVLGNINSLRNDAQMVQVALEQMQ--------DTK-----SE 1395
M+ +K +DV +E+L L ND +++ +E +Q D+K E
Sbjct: 5091 NMMTELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDRE 5150
Query: 1394 LFA-EAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMS 1218
F E E Q LQ + D I+ I +E + Q +++ + + KE +
Sbjct: 5151 AFENEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNR 5210
Query: 1217 KNINLESQNRSLKAELHLQAQKAFQIQEERNVVESE-HNV--LSSEVENLKSELKESKDL 1047
K++ L +NR ++ +K IQ +++++E E HN+ SE+ +K +L++ K+
Sbjct: 5211 KDMVLNEKNRDIE-------EKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKEN 5263
Query: 1046 EGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYE--- 876
++ + + E + ++ + EE++ + DEL L+ E L+ E E
Sbjct: 5264 TLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEI 5323
Query: 875 -YHDYERKNVSGSRAEAMSVLISKSLGNGRANQREF-QNKEEDSSGVDLLKNKCTRLEFQ 702
D + ++ S + ++ + + +++ ++KEE ++ + +
Sbjct: 5324 IMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQS 5383
Query: 701 VQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLR 522
+ L + +M + + + ++ NKLE+M+ L +R +K+E R
Sbjct: 5384 RKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELE----------READEIRKIKEETQNER 5433
Query: 521 ---SEMKGELTPSR-SFKHREGSFIKEINIGDE 435
+M EL + SF H KE I D+
Sbjct: 5434 QSLEKMTEELKKEKESFTHLAEDTKKEQEILDK 5466
Score = 91.3 bits (225), Expect = 2e-15
Identities = 159/754 (21%), Positives = 300/754 (39%), Gaps = 22/754 (2%)
Frame = -1
Query: 2297 VSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQ 2118
++R E+ K+ L E F AL K E I +++ + EL + ++ E+Q
Sbjct: 2582 LNRELEKIKEKKTILAEEFEALDDKKEMI-------GKEMQRLGKMKAELQKEAEDTEKQ 2634
Query: 2117 RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDL 1938
R + ND ++ E+M Q E++++ +RD+ +L+ DR +EK+ DL
Sbjct: 2635 RRDIDNDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLESDRDTLEKERFDL 2694
Query: 1937 ENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQ-TEQNKQLELEIEKLYGS 1761
E K +++K L ++ ES Q IQ E K+ E+ +E+L +
Sbjct: 2695 EKTK------------------TEMKDLEKQLESQSRQHEIQLVEIQKEREI-LEQLKIN 2735
Query: 1760 LQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIE---DELART---- 1602
L ++ + +D EK + + + E Q ++EGI K + I+ DEL +T
Sbjct: 2736 LSKQKEDLEKERDCFEK--EKADISLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNV 2793
Query: 1601 -KEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVA 1425
KE+ + K++ D K+ I L D ++++ N RN+ +MV
Sbjct: 2794 VKELENNEL-QKQIIEDERDKIEQIKAELQKEAKDTEKQRQDI---ENDRRNNEEMV--- 2846
Query: 1424 LEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNA 1245
++Q+ K + ++ D I+ L+ Q L+ + KE ++
Sbjct: 2847 -IKLQNEKKD--------------IETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDL 2891
Query: 1244 KARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL 1065
K + LESQNR + +L +IQ+ER ++E LS + E+L+ E
Sbjct: 2892 KKTNTEMKDLEKQLESQNRQHEIQL-------AEIQKEREILEQLKLTLSKQKEDLEKE- 2943
Query: 1064 KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLR-NENAKLKNE 888
++ + E + L E L Q + E ++ + +DEL R N +L+N
Sbjct: 2944 RDCFEKEKADISLREELQEQS------EREGIGKTRVRIKKEMDELKQTRLNVVKELENN 2997
Query: 887 ALY-EYHDYERKNVSGSRAEAMSVL---------ISKSLGNGRANQREFQNKEED-SSGV 741
L + + ER + +AE I K N + QN+++D +
Sbjct: 2998 ELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETST 3057
Query: 740 DLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXI 561
D ++++ LE Q Q+L + E + + ++ ++ +++ L
Sbjct: 3058 DRIRDEEANLEVQKQRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQ 3117
Query: 560 RVRSLKKENTRLRSEMKGELTPSRS-FKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXX 384
+ R + ++ S+ K +L R F+ + ++ ++ + I
Sbjct: 3118 KEREILEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGID---------- 3167
Query: 383 XKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXX 204
+TRT QE+D L + + Q + +++ +++Q
Sbjct: 3168 ---NTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAEL--------- 3215
Query: 203 KWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKD 102
EK EL L E T+LKKD
Sbjct: 3216 ------KKEAEKTKLELQNERQNLEEAGTKLKKD 3243
Score = 89.7 bits (221), Expect = 5e-15
Identities = 126/682 (18%), Positives = 290/682 (42%), Gaps = 37/682 (5%)
Frame = -1
Query: 2282 EEEKQHTI-ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
E++K++T+ E+Q+ + + NE+I ++ + EQ ++ K E ++ ++ +
Sbjct: 5258 EKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQ-------MNQKQDELDQLKTEI 5310
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
QN Q +E+ + +R + + + L ++ + + ++R ++K +++E QK
Sbjct: 5311 QNLQQELEKEKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQK 5370
Query: 1925 ETVSKELALSVSREQKLASDLKALSEKE---ESTKNQLLIQTEQNK-QLELEIEKLYGSL 1758
+ + KE + L DLK + ++ E KN+L EQ K +LE E +++
Sbjct: 5371 QEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKL----EQMKIELEREADEIRKIK 5426
Query: 1757 QMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSAT 1578
+ Q E L+ E++ + + + + +QE + K + E +A ++ +
Sbjct: 5427 EETQNERQSLEKMTEELKKEKESFTHLAEDTKKEQEILDKVKVANESLMADLQKEKSNLE 5486
Query: 1577 DMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEE---------------------VLGNIN 1461
+M++ S V E L +D+++ L+ E ++ N+
Sbjct: 5487 EMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQQREIEKEKINIESERAAIIKNVE 5546
Query: 1460 SLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQD 1281
L++ + E ++ + E E+ Q L+ E D I+ I +E + Q +++
Sbjct: 5547 DLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEE 5606
Query: 1280 ESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNV 1101
+ + K+ + K++ L +NR ++ +K IQ +++++E E +
Sbjct: 5607 MTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIE-------KKIKSIQSDKDMLEKEKHD 5659
Query: 1100 LS---SEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDE 930
L SE+ +K +L++ K+ ++ L + E + ++ + EE++ + DE
Sbjct: 5660 LEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDE 5719
Query: 929 LICLRNENAKLKNEALYEYH-------DYERKNVSGSRAEAMSVLISKSLGNGRANQREF 771
L L+ E L+ E E +R+ + + I +++ N R ++
Sbjct: 5720 LDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNER--KQLD 5777
Query: 770 QNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLS-DMX 594
++KEE ++ + ++ + L E +M + + + ++ NKLE+M+ L +
Sbjct: 5778 KDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREAD 5837
Query: 593 XXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQ 414
+ + L+K L+ E K + K RE + + E+ + +E +Q
Sbjct: 5838 DIRKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTK-REKNSLDEMKVANESSMADLQ 5896
Query: 413 XXXXXXXXXXXKIDTRTSETQE 348
I +T + ++
Sbjct: 5897 KEKSNLEEMKENISKQTEDIEK 5918
Score = 89.0 bits (219), Expect = 8e-15
Identities = 124/608 (20%), Positives = 262/608 (43%), Gaps = 47/608 (7%)
Frame = -1
Query: 2303 KEVSRLYEE-EKQHTIELQENFNALRQKNEDICLKIEANNNLLEQK---DNIIVELSHKL 2136
KE+ R +E EK E + L ++ + + LL+ K D + E+ +
Sbjct: 887 KEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLFEMDSER 946
Query: 2135 QENEEQRSALQNDMQSVEQMH-----------AVSQTEREELNR---QLVLLRDDVNHLK 1998
+E E+ R ++N+ + +EQ A Q ++EEL + QLV+ + +N +
Sbjct: 947 KELEQMRFQVENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDTESMNRSR 1006
Query: 1997 EALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLL 1818
E +A DR E + +++ Q+E V+K L + RE+ L L+ E E ++
Sbjct: 1007 E---LARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRL-LRKDMENEREDLEKIR 1062
Query: 1817 IQT-----------EQNKQLELEIEKLYGSLQM-KQMENTLLKDGNEKIYDLCKLLATKS 1674
++T E+ ++ EIE+L+ + Q E + E++ + + +
Sbjct: 1063 VETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRKMEAMKREM 1122
Query: 1673 REVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVF 1494
E++ + + KQ NI+ ++ + ++ N LEM MK D+
Sbjct: 1123 GEIEDMKVELTKQKENIDMKMEHAR--------LEMTN----------LEM---MKADLL 1161
Query: 1493 SLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILI 1314
KE++ + + +++ Q QM+ ++E+ + E +++ +AE++ +QH+
Sbjct: 1162 RQKEDIENQMLAAKSERQ-------QMEVMRTEILKQKEDVERKMELAKAEMEKMQHVKD 1214
Query: 1313 ELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQE 1134
E++++ + L++ Q+ +E+ + + K L+ + + + + +IQ
Sbjct: 1215 EIQKQRKELEERMQKTKREIGEMELMKREMEGKKKELDQRMKLTMRKKEEMERLKMEIQR 1274
Query: 1133 ERNVVE---SEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRF 963
++ +E E E+E +K+E++ ++ E + LR+ E L + E +L I
Sbjct: 1275 AKDDMEFKRVETERQKYEMEQVKAEIQRAR--EEFELRVEERDLEEEKEQMNLTI----- 1327
Query: 962 AEEKLMRILDELICLRNENAKLKNE-------ALYEYHDYERKNVSGSRAEAMSVLISKS 804
+ ++ ++ R K K + + D E N R + + +
Sbjct: 1328 -----INLIQQIEATREMVHKTKFQFENRMAGSQMGTADQEEMNAEMQRL-ILEIEHIRE 1381
Query: 803 LGNGRANQREFQNKE---EDSSGVDLLKNKCTR----LEFQVQKLSEKAEMFETKSREAQ 645
+ G + E QNKE D + LLK + R +E++ +K+ + + E S+ Q
Sbjct: 1382 MLRGLKGEVE-QNKEIMKRDREEIRLLKIEVQRRRREIEYREEKIMREQDELELMSKMGQ 1440
Query: 644 QMANKLEE 621
+ +LEE
Sbjct: 1441 RQREELEE 1448
Score = 87.8 bits (216), Expect = 2e-14
Identities = 151/751 (20%), Positives = 299/751 (39%), Gaps = 65/751 (8%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQ--KNEDICLK--------IEANNNLLEQKDNIIV 2154
K++++ EE ++ E+++ + + Q K+ D LK IE N LEQ +
Sbjct: 4070 KQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMK---I 4126
Query: 2153 ELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVD 1974
EL + E + + QN+ Q +E+M EEL ++ KE+ + +
Sbjct: 4127 ELEKEADEIRKIKEETQNERQRLEKM-------TEELKKE-----------KESFTHLAE 4168
Query: 1973 DRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQ 1794
D +K L ++ E++ +L S +++ ++ +E E K ++ ++ ++ +Q
Sbjct: 4169 DTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQ 4228
Query: 1793 LELEIEKLYGSLQMKQMENTL--------LKDGNEKIYDLCKLLAT--KSREVQGQQEGI 1644
L+ EI K G ++M++ N +KD K++ L + L + RE + +
Sbjct: 4229 LQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREV 4288
Query: 1643 LKQ---DI-----NIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFS- 1491
LKQ D+ IE T+ + +M K++ ++E KD V +
Sbjct: 4289 LKQIKTDLKRKAEEIEKIKLETQHDRQRVEEMTAQIQKERDKINNLIEE-TNRKDMVLNE 4347
Query: 1490 LKEEVLGNINSLRNDAQMVQVALEQMQDTKSELF-AEAEIRAQEVLRL------------ 1350
+K E+ I ++ +D M++ ++ T+S+L A+ + Q ++L
Sbjct: 4348 IKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEK 4407
Query: 1349 -----QAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRS 1185
E+ I+H ++K+K QDE + E+ N + L + SQ
Sbjct: 4408 MNEKFTIEIHDIKHQEEQMKQK----QDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDL 4463
Query: 1184 LKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-KESKDLEGYFLRLFEILLG 1008
++EL Q I E + + E E K E+ KE D + L E L
Sbjct: 4464 RQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLKM 4523
Query: 1007 QHVEVASLDIESCRFAEEKL--------MRILDELICLRNENAKLKNEALYEYHDYERKN 852
++ L+ E + + K+ +R + E I +N + EAL E ER++
Sbjct: 4524 MKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKE----ERED 4579
Query: 851 VSGSRAEAMSVLISKSLGNG-------RANQREFQNKEEDSSGVDLLKNKCTRLEFQVQK 693
++ + VL + N R + +E S + ++NK L + +
Sbjct: 4580 LAEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDE 4639
Query: 692 LSE-KAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSE 516
L + +AE+ + + ++ N E + D+ SLK + +E
Sbjct: 4640 LRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENE 4699
Query: 515 MKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTL 336
K L ++ RE I++I + + D ++ +I+ ET D +
Sbjct: 4700 -KEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMV 4758
Query: 335 MDD-NRKYWNRVSHFTKQTQSLQNSVQELQQ 246
+++ NR ++ L+ +L++
Sbjct: 4759 LNEKNRDIEEKIKSIQSDKDMLEKEKHDLEK 4789
Score = 85.9 bits (211), Expect = 7e-14
Identities = 124/662 (18%), Positives = 287/662 (43%), Gaps = 38/662 (5%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIE----ANNNLLEQKDNIIVELSHKL 2136
+E ++++++ L E + E++ ++ E AN + + ++ +++EL +
Sbjct: 3234 EEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIELKKTV 3293
Query: 2135 QENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFME 1956
+ + L+N + + + V Q E + L LL+ ++ + + + E
Sbjct: 3294 TDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQLRLRE 3353
Query: 1955 KQLQDLE------------NQKETVSKELAL-----SVSREQKLASDLKALSEKE----E 1839
+L+ L+ N+K ++++ L + R Q+ + + + K+ E
Sbjct: 3354 VELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYASKDRANLE 3413
Query: 1838 STKNQLLIQTEQNKQLELEIEKLYGSLQMK-QMENTLLKDGNEKIYDLCKLLATKSREVQ 1662
K++++ Q Q+++E+ K G ++ + QM NT K+ ++K L + +E++
Sbjct: 3414 KEKSEMI---AQKHQMDIELNKERGLIEERTQMLNTYEKEMDQK----RTALEVEMKELK 3466
Query: 1661 GQQEGILKQDINIEDELARTK-EVGRSATDMKKVNS---DAGAKVSGILEMLLPMKDDVF 1494
++ I ++ +++L + K E+ R A D+KK+ + + + E L KDD+
Sbjct: 3467 YHKQAIQEE----KNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLA 3522
Query: 1493 SLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILI 1314
L E+ + R D +M + + D + E ++R + + + +D+ + +I
Sbjct: 3523 HLAED------TKRKDDEMKVLHESALADIQKEKCNLEQMR-ESMFKQNEMIDSEKKKMI 3575
Query: 1313 ELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKA-FQIQ 1137
+ K Q +Q E R E+ K+ + N + + +N+ L EL Q++ Q++
Sbjct: 3576 LREDKLQQMQAEINRQQTEMDTKKSIIEN---ERAAMTKKNQDLMTELTKQSEDVEIQMK 3632
Query: 1136 E---ERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCR 966
E E+ ++ES+ +L +VENL+ +L +++ E D E
Sbjct: 3633 EVLTEKELLESDRKLLKKDVENLQQKL---------------LIIESDSESLKQDRELLE 3677
Query: 965 FAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSR----AEAMSVLISKSLG 798
+E L ++ +L E K+K E +E E + + M+ I++ +
Sbjct: 3678 NEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIH 3737
Query: 797 NGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEM 618
+ + +++ + K+++ +D LK + L+ Q+L ++ E+ E ++L++
Sbjct: 3738 DIKYQEKQMKQKQDE---LDQLKTEIQNLQ---QELEKEKEIIMKDRSELDLKQSELDKQ 3791
Query: 617 QQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGD 438
Q ++D+ + ++K E +L + + R + + F + N D
Sbjct: 3792 QTNMNDI-------------IETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLD 3838
Query: 437 ED 432
ED
Sbjct: 3839 ED 3840
Score = 85.1 bits (209), Expect = 1e-13
Identities = 119/600 (19%), Positives = 256/600 (42%), Gaps = 34/600 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEE 2121
E+S++ EE + L++ NAL+++ E + +I+ N +L D I V NE
Sbjct: 6101 EISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVL---DKIKV-------ANES 6150
Query: 2120 QRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDD----RAFMEK 1953
+ LQ + + +E+M RE +++Q+ +D+ + KE + D+ + ++K
Sbjct: 6151 TLADLQKEKRILEEM-------RENISKQI----EDIENEKEKSKLREDELKKLQTEVQK 6199
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTE----QNKQLEL 1785
Q +++ +K + E A + +Q + ++LK SE E ++L + E L+
Sbjct: 6200 QQSEIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKK 6259
Query: 1784 EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 1605
++E L L + ++ LK E + + + ++Q Q + I K + E R
Sbjct: 6260 DVEDLQQKLMSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQR 6319
Query: 1604 TKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVA 1425
+E A++ E + + +++ ++ + + +R + + ++
Sbjct: 6320 VEE--------------KTAQIQKEREEINTLVEEIKKKRDIIDESYTEIRKEKEAIESD 6365
Query: 1424 LEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNA 1245
++ KS+ F + + + +Q + +A++ + E+ R L+DE KE+ A
Sbjct: 6366 RSDLEKAKSQTFKQNKNIEIALAEIQQKRNALEKMSKEISRDRMKLEDEK----KEIQLA 6421
Query: 1244 KARLNNV-------------MSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHN 1104
+ L + + I ES + +AE+ LQ + + + R S+ +
Sbjct: 6422 REELERMHGDMQRQQEAKDHLLSGITDESLLKKSEAEIVLQPSQVDKAKPARKTEISDSD 6481
Query: 1103 -----VLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRI 939
V +LK LK+ + E L + +L Q ++ E+KL I
Sbjct: 6482 KQPVFVQQMPEMDLKDALKKDFESEKLDLPKVKDVLPQDQQMK---------LEQKL--I 6530
Query: 938 LDELICLRNENAKLKNEA-LYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQR---EF 771
DE+ L+ A+L+ EA E + +N + + L + N R N+ +
Sbjct: 6531 EDEMDKLKQMRAELQKEADQIEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINIQK 6590
Query: 770 QNKEEDSSGVDLLKNKCTRLEFQV----QKLSEKAEMFETKSREAQQMANKLEEMQQTLS 603
N+++ ++ + K R++ ++ ++L+++ E + E Q+ LEEM+ +S
Sbjct: 6591 VNQQKQATAFQMEKTDFERIKTEIDQANKELADQQEKNKKTITEMQKERETLEEMRANIS 6650
Score = 85.1 bits (209), Expect = 1e-13
Identities = 120/621 (19%), Positives = 270/621 (43%), Gaps = 60/621 (9%)
Frame = -1
Query: 2279 EEKQH-TIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIV----ELSHKLQENEEQR 2115
++K+H T E ++ + ++ KI+ LE++ ++ L+ L+E + Q+
Sbjct: 9318 DKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQIEAENLNKVLEEIKRQQ 9377
Query: 2114 SALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLE 1935
L+ ++ M + REE R+ + + + + + A + +R ++KQ Q+L+
Sbjct: 9378 EKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQKQELQ 9437
Query: 1934 NQKETVSKELALSVSREQKLASDLKALSEKE---ESTKNQLLIQTEQNKQLELEIEKLYG 1764
Q + + + ++ + + ++L E++ E N++L Q + ++ + ++ K +
Sbjct: 9438 KQADDLDMRM---IAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWN 9494
Query: 1763 SLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRS 1584
L + Q E +++ N+ + ++ E+ G++ I K+ +E+ L + +
Sbjct: 9495 KLDVLQNE---MQNENKAMEEI-------KYELDGKRNEINKEQQRLEESL---RAINEE 9541
Query: 1583 ATDMKKVNSDAGAKVSGILEM----------LLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
D++ + +D + I EM L +K ++ K E+ L ND M+
Sbjct: 9542 KGDLEIMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMI 9601
Query: 1433 Q--------------VALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIEL---- 1308
+ +QM+D +SEL + + E +++ + ++ ++ E+
Sbjct: 9602 EKERNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQR 9661
Query: 1307 ---KRKNQTLQDESQRNAKE---LWNAKARLNNVMSKNINLE----SQNRSLK-AELHLQ 1161
K K + L E Q E L + L N + N+E ++ +LK E HLQ
Sbjct: 9662 NDFKLKKEELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQ 9721
Query: 1160 AQK--AFQIQEERNVVESEHNVLSSEVENLKSELKESKD-LEGYFLRLFEILLGQHVEVA 990
K I EE + + + +S+ + K ELK KD LE + +
Sbjct: 9722 RDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRID 9781
Query: 989 SLDIESCRFAEEKL---MRILDELICLRNENAK---LKNEALYEYHDYERKNVSGSRAEA 828
D + + EE L ++ +E CL N K +K +A E+H+ +K + +
Sbjct: 9782 EFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQK-IEELQTLQ 9840
Query: 827 MSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREA 648
++ K + + + ++ D +L++ K T ++ + +KL++ +M E + +
Sbjct: 9841 EQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREK-TEVDHEQKKLNDDIKMIEQEKEDL 9899
Query: 647 QQMANKL----EEMQQTLSDM 597
++M +++ +EM++ S++
Sbjct: 9900 EKMKSEIMTQKQEMEKERSEL 9920
Score = 85.1 bits (209), Expect = 1e-13
Identities = 116/634 (18%), Positives = 264/634 (41%), Gaps = 36/634 (5%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
K S + ++ +Q E E N +RQ + C IE + ++++ + E H++Q +
Sbjct: 11293 KMKSEIMKQRQQMEEERSELENKIRQTYIEKC-DIENSKEIVQKLMVEVEEQKHEIQFQK 11351
Query: 2123 EQ------------------RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLK 1998
E+ +S LQN+ + ++ ++ V + ERE L L + +K
Sbjct: 11352 EELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMK 11411
Query: 1997 EALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLL 1818
+ +EK + QK+ + + L +++ K L ++ + Q+
Sbjct: 11412 SITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVS 11471
Query: 1817 IQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILK 1638
Q E++ E E+++ SL+ + +K E +E + ++E +
Sbjct: 11472 KQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEP--------EEIKKEKEKEEE---E 11520
Query: 1637 QDINIEDELARTKEVGRSATDMKKVNSDAG---AKVSGILEMLLPMKDDVFSLKEEVLGN 1467
Q++ ++ E+ R KE+ + + +++V S+ K++ +M+ K+D+ +K E++
Sbjct: 11521 QEMRVKVEMER-KEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQ 11579
Query: 1466 INSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTL 1287
+ + + ++Q K ++ EI + ++ ++ + IQ EL + Q +
Sbjct: 11580 RQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKI 11639
Query: 1286 QDESQ---RNAKELWNAKARLNNVMSKNINLESQN-RSLKAELHLQAQKAFQIQEERNVV 1119
DE +N E N R+ M + I E + + ++ L + ++ + EE
Sbjct: 11640 ADEQDLLIQNKIEQQNENERIKE-MDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRR 11698
Query: 1118 ESEHNVLSSEVENLKSELKESKDL---EGYFLRLFEILLGQHVE--------VASLDIES 972
+ + +S+++ K +L +DL E + L Q ++ + + +E
Sbjct: 11699 KEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEE 11758
Query: 971 CRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNG 792
+EKL + + E + E + + E D ++N E M L+ K +
Sbjct: 11759 KTEMDEKLQQAIKEYESIIEETNRKRTELEEIEVDQSQQN---KNVETMKDLLEKERKDT 11815
Query: 791 RANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQ 612
+ E Q K+ D + ++++ + E + L E+ ++ E K+ E + + LE+ ++
Sbjct: 11816 EKEREELQ-KQADDLEMQMIEHG-DKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKE 11873
Query: 611 TLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK 510
DM +++ K E ++ E++
Sbjct: 11874 ---DMMKKWNELDGLQKEIQNQKNEMEEIKCELE 11904
Score = 84.3 bits (207), Expect = 2e-13
Identities = 147/702 (20%), Positives = 294/702 (41%), Gaps = 78/702 (11%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQEN---FNALRQKNEDICLKIEANNNLLE------QKDNIIVE 2151
+EV +E +Q T +L+E+ F+ ++KN I +I+ ++ LE K+ I E
Sbjct: 2208 QEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTIFE 2267
Query: 2150 LSHK---LQENE-----EQRSALQNDMQ----SVEQMHAVSQTER--------------- 2052
L + L+ENE +Q LQN ++ VEQM A +R
Sbjct: 2268 LEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTARGRETT 2327
Query: 2051 --EELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQK 1878
EE +++ LR++ ++++ + + E +++ LE + E + K+ + +E +
Sbjct: 2328 ALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAM-KKYKEKLDKEYE 2386
Query: 1877 LASDLKALSEKE-ESTKNQLLIQTE--QNKQLELEIEK--LYGSLQMKQMENTLL-KDGN 1716
+ L EKE + + +L I+ E + K+ ELEI+K +Y M + + ++ K
Sbjct: 2387 DLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKT 2446
Query: 1715 EKIYDLCKLLATKSREVQGQQEGILKQDINI-EDELARTKEVGRSATDMKKVN---SDAG 1548
+++ ++ K + EV+ Q+ +++ ++ I ++E KE R + N S
Sbjct: 2447 DELDEVRKKINADLSEVEKQKSALVQMNLKISQEESYVKKEKDRLKLQENEQNMQMSQLN 2506
Query: 1547 AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRA 1368
AK + + E M+ L E V+ + + + + + +MQ+ A ++
Sbjct: 2507 AKQNELDERQAEMEKQKREL-ENVMDRLEKEKVEITKEKQRVNEMQNEVKRKNASVDLIK 2565
Query: 1367 QEVLRLQAEVDAIQHI----LIELKRKN-------QTLQDESQRNAKELWNAKARLNNVM 1221
QEVLR Q ++ + I L ++K K + L D+ + KE+ +
Sbjct: 2566 QEVLREQDHIENSREILNRELEKIKEKKTILAEEFEALDDKKEMIGKEMQRLGKMKAELQ 2625
Query: 1220 SKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-------- 1065
+ + E Q R + + + ++Q E+ +E+ + + E NL+ +
Sbjct: 2626 KEAEDTEKQRRDIDNDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLESDRD 2685
Query: 1064 ---KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLK 894
KE DLE + + L + +E S E +K IL++ L+ +K K
Sbjct: 2686 TLEKERFDLEKTKTEMKD--LEKQLESQSRQHEIQLVEIQKEREILEQ---LKINLSKQK 2740
Query: 893 NEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEE-DSSGVDLLKNKCT 717
+ E +E++ S E + K G + R Q +E + + ++++K +
Sbjct: 2741 EDLEKERDCFEKEKADISLREELEEQSEKE-GIDKTRVRIKQEMDELEQTRLNVVK-ELE 2798
Query: 716 RLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTL-SDMXXXXXXXXXXXIRVRSLKK 540
E Q Q + ++ + E E Q+ A E+ +Q + +D + ++
Sbjct: 2799 NNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIET 2858
Query: 539 ENTRLRSE------MKGELTPSRSFKHREGSFIKEINIGDED 432
R+R E +K L R +E +K+ N +D
Sbjct: 2859 STDRIRDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEMKD 2900
Score = 84.3 bits (207), Expect = 2e-13
Identities = 158/788 (20%), Positives = 326/788 (41%), Gaps = 59/788 (7%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNII----VELSHKLQENEEQR 2115
EE+KQ + ++N + R+ ++ K++ + E++ N + +EL + E + +
Sbjct: 4911 EEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIK 4970
Query: 2114 SALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLE 1935
QN Q +E+M EEL R+ KE+L+ +D +K L +++
Sbjct: 4971 EETQNKRQRLEKM-------TEELIRE-----------KESLAHLAEDTKTEKKILDEMK 5012
Query: 1934 NQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQ 1755
E+ +L S +++ ++ L E ++ K + ++ ++ K+L+ E++K +
Sbjct: 5013 VANESSMADLQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKID 5072
Query: 1754 MKQ--MENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSA 1581
M++ +E+ EK ++ L KS +V+ Q + IL E EL
Sbjct: 5073 MEKTNIESERAAMIREK-QNMMTELKKKSEDVEIQMKEIL-----TEKELLH-------- 5118
Query: 1580 TDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQM---VQVALEQMQ 1410
D K + D V + + L+ ++ D LK + N QM +Q+ ++++
Sbjct: 5119 NDRKLLTRD----VENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEIE 5174
Query: 1409 DTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLN 1230
K E + + + ++Q E D I +++ E RK+ L ++++ +++ + ++ +
Sbjct: 5175 KIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKD 5234
Query: 1229 NVMSKNINLESQNRSL-KAELHLQAQK---AFQIQEERNVVE------------------ 1116
+ + NLE L K + L+ QK +IQ+ER VE
Sbjct: 5235 MLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEE 5294
Query: 1115 ------SEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAE- 957
E + L +E++NL+ EL++ K++ F++ + LD + +
Sbjct: 5295 QMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQFDL------RQSELDKQQTNMNDI 5348
Query: 956 -EKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQ 780
E + +L + E + K E E HD+++ S + + + + K + N+
Sbjct: 5349 METMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDK-DLKMMKLQKQVFEEEKNK 5407
Query: 779 REFQNKEEDSSGVDLLK------NKCTRLEFQVQKLSEKAEMF---ETKSREAQQMANKL 627
E E + ++ K N+ LE ++L ++ E F +++ Q++ +K+
Sbjct: 5408 LEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFTHLAEDTKKEQEILDKV 5467
Query: 626 E--------EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHRE 471
+ ++Q+ S++ V + KKEN RLR + +L + RE
Sbjct: 5468 KVANESLMADLQKEKSNLEEMRENISKQTEDVEN-KKENLRLREDELWQLQAEIYKQQRE 5526
Query: 470 GSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFT 291
I++ I E + I +D R SE+ ++D R+ +
Sbjct: 5527 ---IEKEKINIESERAAIIKNVEDLQHKIISLD-RDSESLKLD------REAFENEREVL 5576
Query: 290 KQTQS-LQNSVQELQQXXXXXXXXXXXXXXKWGGI--DMNSIEKQLKELNIHVMQLVEHN 120
KQ ++ L+ E+++ I D + I ++E N M L E N
Sbjct: 5577 KQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKN 5636
Query: 119 TRLKKDVK 96
++K +K
Sbjct: 5637 RDIEKKIK 5644
Score = 84.0 bits (206), Expect = 3e-13
Identities = 140/786 (17%), Positives = 327/786 (41%), Gaps = 26/786 (3%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQ-----ENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHK 2139
+E + EE K IE++ E ++K E+ ++ + E+ D I +L
Sbjct: 10930 EEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKK-EELDQIKSQLERV 10988
Query: 2138 LQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFM 1959
E + ++ L +D + +EQ + + E+ +Q + ++ + L + +R
Sbjct: 10989 RSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLER--- 11045
Query: 1958 EKQLQDLENQKETVSKELA--------LSVSREQKLASDLKALSEKEESTKNQLLIQTEQ 1803
D+EN KE V K + + + +E+ K E+ +N+ +Q E
Sbjct: 11046 ----HDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNEN 11101
Query: 1802 NKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQD--- 1632
+ E++ E +K+ME L K+ E + + + +++ + KQ+
Sbjct: 11102 ERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDL 11161
Query: 1631 INIEDELARTK-EVGRSATDMKKVNSDAGAKVSGILEMLL----PMKDDVFSLKEEVLGN 1467
+N D L + + E+ T +++ + A+VS E L M+++ SL+E +
Sbjct: 11162 MNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKI-K 11220
Query: 1466 INSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTL 1287
I ++ + ++ E+ ++ + + A+ E++ +E+ +++++++ ++ E+ + + L
Sbjct: 11221 IIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRS---EIDHEQKKL 11277
Query: 1286 QDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEH 1107
D+ + +E + + + +M + +E + L+ ++ + I+ + +V+
Sbjct: 11278 NDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQK-- 11335
Query: 1106 NVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL 927
L EVE K E++ K+ LDIE + A+E+ + I ++
Sbjct: 11336 --LMVEVEEQKHEIQFQKE--------------------ELDIERQKIADEQDLLIQNKS 11373
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSS 747
L+NEN ++KN + E ER+ + + M + K ++ E + ++ED
Sbjct: 11374 E-LQNENERIKN--INEVIKKERETL-----KEMEAYLEKEKEEMKSITEETRRQKED-- 11423
Query: 746 GVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXX 567
L+ T + Q Q L + ++ E +E +++ +K +++QQ + +
Sbjct: 11424 ----LEKMSTHINEQKQDLRSQRDLLE---QEREEINHKWKQLQQRIDEFDAQVSKQKEE 11476
Query: 566 XIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXX 387
+ KE+ + E K + ++ E IK+ +E++ Q
Sbjct: 11477 DLPKEKEMKEDRKSLEETKANILEMKT--KAEPEEIKKEKEKEEEE----QEMRVKVEME 11530
Query: 386 XXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQ-TQSLQNSVQELQQXXXXXXXXXXXX 210
+I+ S+ + + + MD +K N +Q + L+ E+ +
Sbjct: 11531 RKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMK------------ 11578
Query: 209 XXKWGGIDMNSIEKQLKELNIHVMQ--LVEHNTRLKKDV--KFGFAWANSMHDLNGQEQK 42
+E++ EL+ + Q L +H+ K++ K H++ Q+++
Sbjct: 11579 -------QRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEE 11631
Query: 41 LKVDEE 24
L ++ +
Sbjct: 11632 LDIERQ 11637
Score = 83.6 bits (205), Expect = 4e-13
Identities = 153/813 (18%), Positives = 320/813 (39%), Gaps = 62/813 (7%)
Frame = -1
Query: 2276 EKQHTI---ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
EKQ I E+Q+ L + NE ++I + EQ + K E ++ ++ +
Sbjct: 4388 EKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQ-------MKQKQDELDQLKTEI 4440
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
QN Q +E+ + +R +L+ + L ++ + + ++R ++K ++ E QK
Sbjct: 4441 QNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQK 4500
Query: 1925 ETVSKELALSVSREQKLASDLKALS------EKEESTKNQLLIQTEQN----KQLELEI- 1779
+ + KE + L DLK + E E+S Q+ I+ E+ ++++ EI
Sbjct: 4501 QEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQ 4560
Query: 1778 ------EKLYGSLQMKQMENTLLKDGNEKIYD---------LCKLLATKSREVQGQQEGI 1644
EK+ +L+ ++ + N ++ D L +L KS ++ +E I
Sbjct: 4561 NERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKS-NLEEMRENI 4619
Query: 1643 LKQDINIEDE----LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEV 1476
KQ ++E++ R E+ + ++ K + + I + DV L+ ++
Sbjct: 4620 SKQTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKI 4679
Query: 1475 LGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKN 1296
+ L DA+ +++ E ++ E E+ Q L+ E D I+ I +E +
Sbjct: 4680 I----CLDRDAESLKLDREAFEN-------EKEVLKQMKTELEREADEIEKIKLETQHDR 4728
Query: 1295 QTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVE 1116
Q +++ + + K+ + K++ L +NR ++ +K IQ +++++E
Sbjct: 4729 QRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIE-------EKIKSIQSDKDMLE 4781
Query: 1115 SEHNVLS---SEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLM 945
E + L SE+ +K +L++ K+ ++ L + E + ++ + EE++
Sbjct: 4782 KEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMN 4841
Query: 944 RILDELICLRNENAKLKNEALYE----YHDYERKNVSGSRAEAMSVLISKSLGNGRANQR 777
+ DEL L+ E L+ E E D + ++ S + ++ + + ++
Sbjct: 4842 QKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERK 4901
Query: 776 EF--------QNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLE- 624
+ + K+E D + L+ +K+ + +MFE + + +QM +LE
Sbjct: 4902 QLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELER 4961
Query: 623 -------------EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSF 483
+Q L M + K ++ EMK S +
Sbjct: 4962 EADEISKIKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMAD 5021
Query: 482 KHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRV 303
RE S ++E+ I ++ +E Q+ + +D + N
Sbjct: 5022 LQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKT--NIE 5079
Query: 302 SHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEH 123
S + QN + EL++ +E Q+KE+ L
Sbjct: 5080 SERAAMIREKQNMMTELKK-------------------KSEDVEIQMKEILTEKELLHND 5120
Query: 122 NTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEE 24
L +DV+ + DL ++LK+D E
Sbjct: 5121 RKLLTRDVE---NLQQKLIDLERDSKRLKLDRE 5150
Score = 83.6 bits (205), Expect = 4e-13
Identities = 128/620 (20%), Positives = 275/620 (44%), Gaps = 63/620 (10%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLE-QKDNIIVELSHKLQEN 2127
+E S L ++ KQ +E + N+ ++ E + +++E + ++ QK+ + +E E
Sbjct: 11585 EERSELDKKIKQTDLEKHDIENS-KEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQ 11643
Query: 2126 E---EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFME 1956
+ + + QN+ + +++M + ERE L V L+ + ++ + + +E
Sbjct: 11644 DLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLE 11703
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSEK--EESTKNQLLI------QTEQN 1800
K D+ QK+ + + L +++ L L ++ E T + +L+ +TE +
Sbjct: 11704 KMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMD 11763
Query: 1799 KQLELEIEKLYGSLQMKQMENTLLKD-------GNEKIYDLCKLLATKSREVQGQQEGIL 1641
++L+ I++ ++ + T L++ N+ + + LL + ++ + ++E +
Sbjct: 11764 EKLQQAIKEYESIIEETNRKRTELEEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQ 11823
Query: 1640 KQDINIEDELAR---TKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLG 1470
KQ ++E ++ +E+ + + D +K + A +L +DD+ KE+++
Sbjct: 11824 KQADDLEMQMIEHGDKEEMSKRSLDEEKKLLEQKANE------ILRQRDDLEKEKEDMMK 11877
Query: 1469 NINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAI------------- 1329
N L + +Q +M++ K EL + +E RL+ ++ +
Sbjct: 11878 KWNELDGLQKEIQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLEIVRVD 11937
Query: 1328 ----QHILIELKRKNQTLQDE-SQRNAKELWNAKARLNNVMSKNI------NLESQNRSL 1182
Q + E++ K + +DE Q AK L + K N SK++ +E +L
Sbjct: 11938 YEKHQQQIEEMRVKTKMERDELDQLMAKMLMDRK---ENERSKDMIGLLKKEMEQTKFNL 11994
Query: 1181 KA---ELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILL 1011
A EL L+ QK +++ + ++E +SEV+ LK + E KD + + E L
Sbjct: 11995 DAQEEELKLEKQKIQNEKKDLEMFKAEIKREASEVKTLKEQQLE-KDTKAFEALKEEHLP 12053
Query: 1010 GQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKL-KNEALYEYHDYERKNVSGSR- 837
GQ V+ + E + E K RIL E + E +L +N+ + E+ + +
Sbjct: 12054 GQFVQQKGGEFERIQIDEVK--RILSE---IHKEKKELERNKQILEHQREALLEIKSKQP 12108
Query: 836 AEAMSVLISKS---------LGNGRANQREFQNKEEDSSGVDLLKNKCTRL---EFQVQK 693
+E + V++ S + + A+Q E K D++K T + E+++ K
Sbjct: 12109 SERLDVILVSSATQTSDLEDIPDVSASQGETVEKH-----TDIIKEYTTSIPKEEYEIDK 12163
Query: 692 LSEKAEMFETKSREAQQMAN 633
L ++ + +RE +MA+
Sbjct: 12164 LKQQGDKKLKSTREDTKMAD 12183
Score = 83.6 bits (205), Expect = 4e-13
Identities = 137/665 (20%), Positives = 282/665 (42%), Gaps = 98/665 (14%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNI---IVELSHKLQE 2130
E+ +L ++ ++ EL++ L+++ + KI+A Q D I I L + +E
Sbjct: 12537 EIQKLRKQYEKEKCELEQIKPDLQKREPE---KIDAE----VQHDEIHGGIDSLKEEREE 12589
Query: 2129 NEEQRSALQNDMQSVEQMHAVSQTEREELNR------QLVL----------LRDDVNHLK 1998
E+ ++ LQN ++ E M + + E++EL + Q+ + L+D++ ++
Sbjct: 12590 IEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIE 12649
Query: 1997 EALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKA-----LSEKEEST 1833
L + + ++E+ ++L +K + + + +L +K +S+ EE
Sbjct: 12650 AILKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKMEERE 12709
Query: 1832 KNQLLIQ------TEQNKQLELEIEKLYG-SLQMKQMENTLLKDGNEKIYDLCKLLATKS 1674
+ I+ E++++++ E E+L ++K+ L + NE + K
Sbjct: 12710 AERKTIERVMDEMAEEHEKIKKEREELVNMEEEIKKQRRVLEESMNE--------MTKKK 12761
Query: 1673 REVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGIL----EMLLPMK 1506
E+Q ++ + KQ +ED +A S D+ S + IL E + MK
Sbjct: 12762 SELQHERSELYKQKQQLEDMIA-----SESKRDVDTERSRQDKEDEQILKREREEIADMK 12816
Query: 1505 DDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSE--------LFAEAEIRA------ 1368
D + KE+V + + + ++ Q+ D K E L+ + EI+
Sbjct: 12817 DQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEIQVKTNALE 12876
Query: 1367 ---QEVLRLQAEVDA--IQH---------ILIELKRKNQTLQDESQRNAKELWNAKARL- 1233
Q++ + + V+A IQH ++ E KRK + + E QR +++ + K RL
Sbjct: 12877 KMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFEDIESVKVRLV 12936
Query: 1232 ---NNVMSKNINLESQNRSLKAELHLQAQKAF-----QIQEERNVVESEHNVLSSEVENL 1077
N + N L++++ L+ L + QK F ++Q ER +E + L + L
Sbjct: 12937 TESNQIDKMNSELKTRSEELE-NLIKKQQKEFETKENEMQRERKALEKMNAELERKSTEL 12995
Query: 1076 KSELKE----SKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEK---------LMRIL 936
K+++++ DL+ + E+ E + L E + ++K + +
Sbjct: 12996 KNKIEKVTVWEADLQKEKNKTEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEM 13055
Query: 935 DELICLRNENAKLKNEAL----YEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQ 768
+ L CLRNE K L E H+ ++ ++E S+ K ++ E +
Sbjct: 13056 ENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTE-IQSEKESIEEEKKTLKQLKDENESK 13114
Query: 767 NKEEDSSGVDLLKNKCTRLEFQVQK---------LSEKAEMFETKSREAQQMANKLEEMQ 615
+ D++ + K +L Q +K L KAE + + R+A Q+ +++ +
Sbjct: 13115 RTQLDNT---IEKMNMDKLSIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDA 13171
Query: 614 QTLSD 600
+ L D
Sbjct: 13172 KILDD 13176
Score = 79.7 bits (195), Expect = 5e-12
Identities = 114/611 (18%), Positives = 267/611 (43%), Gaps = 43/611 (7%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
K S L + +Q E E +++ N + KIE N ++E+ + E + + +
Sbjct: 9610 KMKSELMTQRQQMEDERSELDQKIKEANTEKD-KIEKNKEIVERLMAEVEEQRNDFKLKK 9668
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNH----LKEALSMAVDDRAFME 1956
E+ + + ++ + + A +TE + + Q+ + + V + LKE + D+ ++
Sbjct: 9669 EELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIK 9728
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQ-----NKQL 1791
+++ QKE + K ++ ++ +++ + K E+E N Q +Q + Q+
Sbjct: 9729 SIIEETSRQKEDLEK-ISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQV 9787
Query: 1790 ELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKL-------LATKSREVQGQQEGILKQD 1632
+ E+ + + + E L++ N KI ++ + K E+Q QE I+K+
Sbjct: 9788 RKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEK 9847
Query: 1631 INIEDELARTKEVGRSATDMKKVNSD----------AGAKVSGILEMLLPMKDDVFSLKE 1482
E A T ++ D+ ++ S+ K++ ++M+ K+D+ +K
Sbjct: 9848 EKAE---AMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKS 9904
Query: 1481 EVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKR 1302
E++ + + + ++Q K ++ EI + + ++ + IQ EL
Sbjct: 9905 EIMTQKQEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDI 9964
Query: 1301 KNQTLQDESQ---RNAKELWNAKARLNNVMSKNINLESQNRSLK-AELHLQAQKAFQIQE 1134
+ Q + DE +N EL N R+ N+ N ++ + +LK E HL+ +K E
Sbjct: 9965 ERQKIADEQDLLIQNKSELQNENERIRNI---NEVIKKERETLKEMEAHLEKEK-----E 10016
Query: 1133 ERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEE 954
E + E ++E + +++KE + L+ Q ++ + E
Sbjct: 10017 EMKSITEETRRQKEDLEKMSTDIKEQN----------QDLMKQR-DLLEQEKEDINHEWT 10065
Query: 953 KLMRILDELICLRNENAKLKNEALYEYHDY--ERKNVSGSRAEAMSVLISKSLGNGRANQ 780
+L + +DE + +K K E L + + ERK++ ++A + + L + + +
Sbjct: 10066 QLQQRIDEFDA---QVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEK 10122
Query: 779 REFQNKEE-------DSSGVDLLKNKCTR----LEFQVQKLSEKAEMFETKSREAQQMAN 633
+ + +EE D +D +K++ R ++ + +KL++ ++ E + + ++M +
Sbjct: 10123 EKEEEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKS 10182
Query: 632 KLEEMQQTLSD 600
++ + +Q + +
Sbjct: 10183 EIMKQRQQMEE 10193
Score = 79.7 bits (195), Expect = 5e-12
Identities = 106/593 (17%), Positives = 267/593 (45%), Gaps = 25/593 (4%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLE-QKDNIIVELSHKLQEN 2127
+E S L + KQ IE + N+ ++ + + +++E + ++ QK+ + +E E
Sbjct: 10193 EERSELENKIKQTYIEKCDIENS-KEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQ 10251
Query: 2126 E---EQRSALQNDMQSVEQMHAVSQTERE---ELNRQLVLLRDDVNHLKEALSMAVDDRA 1965
+ + +S LQN+ + + ++ + + ERE E+ L ++++ + E +D
Sbjct: 10252 DLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRLKED-- 10309
Query: 1964 FMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLEL 1785
+EK D+ Q + + + L +++ K L ++ + Q+ Q EQ+ E
Sbjct: 10310 -LEKMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEK 10368
Query: 1784 EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 1605
+++ SL+ + +K E K +E + ++E +++I + E R
Sbjct: 10369 GMKEDRKSLEETKANVIEMKTKAEPEE------IKKEKEKENEEEEEEEEEIRVIVETER 10422
Query: 1604 TKEVGRSATDMKKVNSDAG---AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
KE+ + +++++V S+ K++ ++M+ K+D+ +K E++ + + +
Sbjct: 10423 -KELYQIKSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSEL 10481
Query: 1433 QVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQ---RNA 1263
++Q K ++ EI + ++ ++ + IQ EL + Q + DE +N
Sbjct: 10482 DNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQNK 10541
Query: 1262 KELWNAKARLNNVMSKNINLESQNRSLK-AELHLQAQKAFQIQEERNVVESEHNVLSSEV 1086
+L N R+ V + ++ + +L+ E+HL+ +K +E R+++E E ++
Sbjct: 10542 AKLQNENERIKKV---DEEIKKERETLREMEIHLKKEK----EELRSIIE-ETQRRKEDL 10593
Query: 1085 ENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNEN 906
E + +++ E K + L ++ + E +L + +DE +
Sbjct: 10594 EKMSTDINEQK-----------LHLKNQRDLLEQEREEINHEMTQLQQRIDEFDA---QV 10639
Query: 905 AKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDL--- 735
+K + + + + ERK++ ++A + + L ++E +++EE V++
Sbjct: 10640 SKQREDLTKQEMEEERKSLEETKARIIEMKTKAEL-QEIMQEKEEEDEEEMRVIVEMERE 10698
Query: 734 --------LKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSD 600
LK + ++ + +KL++ ++ E + + ++M +++ +Q + +
Sbjct: 10699 ELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEE 10751
Score = 79.3 bits (194), Expect = 7e-12
Identities = 138/744 (18%), Positives = 296/744 (39%), Gaps = 65/744 (8%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNII----VELSHKLQENEEQR 2115
EE+K+ + + +F+ R ++ ++ + E++ N + +EL + E + +
Sbjct: 3817 EEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIK 3876
Query: 2114 SALQNDMQSVEQM------------HAVSQTER--------------------------E 2049
+QN+ QS+E+M H T++ E
Sbjct: 3877 EEIQNERQSLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEKSNFE 3936
Query: 2048 ELNRQLVLLRDDVNHLKEALSMAVDD----RAFMEKQLQDLENQKETVSKELALSVSREQ 1881
E+ + +DV + KE L + D+ +A + KQ +++E +K + E A + +
Sbjct: 3937 EMRENISKQTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVE 3996
Query: 1880 KLASDLKALSEKEESTK-------NQLLIQTEQNKQLEL---EIEKLYGSLQ-MKQMENT 1734
L + +L ES K N+ + + +LE EIEK+ Q +Q
Sbjct: 3997 DLQHKIISLDRDAESLKLDREAFENEREVLKQMKTELEREADEIEKIKLETQHERQRVEE 4056
Query: 1733 LLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSD 1554
+ D E + + K L E+Q Q++ + K+ +++ + + K+V +
Sbjct: 4057 MTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEE 4116
Query: 1553 AGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEI 1374
K+ + L D++ +KEE +N+ Q ++ E+++ K AE
Sbjct: 4117 EKNKLEQMKIELEKEADEIRKIKEET-------QNERQRLEKMTEELKKEKESFTHLAED 4169
Query: 1373 RAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQ 1194
E L A + ++ +L+++ L++ + +K+ +++ + + LE
Sbjct: 4170 TKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELE-- 4227
Query: 1193 NRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEIL 1014
L+AE+H Q +I+ E++ ESE + +V++L+ ++
Sbjct: 4228 --QLQAEIHKQQG---EIKMEKSNNESERAAIIKDVKDLQHKM---------------FS 4267
Query: 1013 LGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRA 834
L + +E LD E+ E L +I +L E K+K E HD + R
Sbjct: 4268 LDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIKLET---QHDRQ-------RV 4317
Query: 833 EAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKC-TRLEFQVQKLSEKAEMFETKS 657
E M+ I K + + N E+++ D++ N+ T ++ +++ + +M E +
Sbjct: 4318 EEMTAQIQK-------ERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEK 4370
Query: 656 REAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKH 477
+ ++ +KL ++ L I++ ++KE L + KH
Sbjct: 4371 HDLEKTRSKLLRAKENLEKQ---------RKIKLAEIQKEREDLEKMNEKFTIEIHDIKH 4421
Query: 476 REGSFIKEINIGDEDDTPL------IQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKY 315
+E ++ + D+ T + ++ ++D R SE + T ++D +
Sbjct: 4422 QEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMET 4481
Query: 314 W-NRVSHFTKQTQSLQNSVQELQQ 246
N K + + QE+++
Sbjct: 4482 MKNERKQLDKDKEETEEQKQEMEK 4505
Score = 77.4 bits (189), Expect = 3e-11
Identities = 122/621 (19%), Positives = 274/621 (44%), Gaps = 65/621 (10%)
Frame = -1
Query: 2273 KQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQ-ENEEQRSALQND 2097
KQ EL++ L ++ E+ E ++E + + I ++ +L+ E E+ + LQN+
Sbjct: 3174 KQEMDELEKTRQNLAKEQENN----ELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNE 3229
Query: 2096 MQSVEQMHAVSQTER-------EELNRQLVLLRD-----DVNHLKEALSMAVDDRAFME- 1956
Q++E+ + +R EEL R+ V+L + ++ + + +R +E
Sbjct: 3230 RQNLEEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIEL 3289
Query: 1955 -KQLQDLENQKETVSKELALSVSREQKLASDLKALSE-----KEESTKNQLLI--QTEQN 1800
K + D+ KE + +L + + ++++A + K+ ++ Q+ I +TEQ
Sbjct: 3290 KKTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQL 3349
Query: 1799 KQLELEIEKLYGSLQMKQMENTLLKDGNEK--IYDLCKLLATKS------REVQGQQEGI 1644
+ E+E+E+L + +Q E + N K I + +L K+ REV E
Sbjct: 3350 RLREVELEQLQALIYRQQDE----IEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYA 3405
Query: 1643 LKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNI 1464
K N+E E +++ + + ++N + G + +ML + ++ + + +
Sbjct: 3406 SKDRANLEKE--KSEMIAQKHQMDIELNKERGL-IEERTQMLNTYEKEMDQKRTALEVEM 3462
Query: 1463 NSLRNDAQMVQVALEQMQDTKSELFAEAE--IRAQEVLR------------LQAEVDAIQ 1326
L+ Q +Q ++Q K EL EA+ + +E R L+ E D +
Sbjct: 3463 KELKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLA 3522
Query: 1325 HILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAF 1146
H+ + KRK+ ++ + ++ K L + S K ++ L+ K
Sbjct: 3523 HLAEDTKRKDDEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQ 3582
Query: 1145 QIQEE-----------RNVVESEHNVLSSEVENLKSEL-KESKDLEGYFLRLFEILLGQH 1002
Q+Q E ++++E+E ++ + ++L +EL K+S+D+E +++ E+L +
Sbjct: 3583 QMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVE---IQMKEVLTEKE 3639
Query: 1001 V-----EVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSR 837
+ ++ D+E+ ++KL+ I + L+ + L+NE E + ++ G
Sbjct: 3640 LLESDRKLLKKDVEN---LQQKLLIIESDSESLKQDRELLENEK--EVLKQMKTDLQGEA 3694
Query: 836 AEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTR----LEFQVQKLSEKAEMF 669
E + + R + Q ++D + + + TR +++Q +++ +K +
Sbjct: 3695 EEIEKIKLETQHERQRVEEMTAQ-IQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDEL 3753
Query: 668 ETKSREAQQMANKLEEMQQTL 606
+ E Q + +LE+ ++ +
Sbjct: 3754 DQLKTEIQNLQQELEKEKEII 3774
Score = 77.0 bits (188), Expect = 3e-11
Identities = 132/656 (20%), Positives = 271/656 (41%), Gaps = 38/656 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQ-HTIELQENFNALRQKNEDIC-LKIEANNNLLEQK--DNIIVELSHKLQ 2133
E S++ +EK+ E+Q + Q E++ LK E N ++ + + EL K Q
Sbjct: 8221 EESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQ 8280
Query: 2132 ENEEQRSALQNDMQSVEQMHAVSQTERE--ELNRQLVLLR---------DDVNHLKEALS 1986
E E R LQ + + +EQ+ E+E E++R+LV DV KE L
Sbjct: 8281 EEESMREILQKEKEELEQLKKDINREKEDIEISRELVESEIYEGEVKGFTDVQKYKEELQ 8340
Query: 1985 MAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALS---EKEESTKNQLLI 1815
+ ++ ++ L+ L + + + + L + K ++L+ ++ +K E +
Sbjct: 8341 IVTEELLTKKRNLEQLNSDVQHLMQTLEEVDIQYIKKKAELEHITSEIQKREQILEKQKK 8400
Query: 1814 QTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKL-----------LATKSRE 1668
+ E+N + EIE + +L+ ME ++ EK + + L + E
Sbjct: 8401 KLEENGWIIEEIEMMKVTLESINMEILQKREDMEKEKENLRREKQETELFRGELQRQRDE 8460
Query: 1667 VQGQQEGI--------LKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLP 1512
V+ ++ + LK D + A ++ + +M+ + AK++ L
Sbjct: 8461 VESSRQALIMEKDQFKLKIDHQRNEMSAAFEKEHKRLENMENDLENQRAKLAESLNDAAK 8520
Query: 1511 MKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDA 1332
M+ + +K E+ + QMV+ +++ K E+ + + +LQ + +
Sbjct: 8521 MEQKLQQMKNELNKEKEQVEEMKQMVKTERVKIEQEKEEMRKQTQEIEDGHEKLQKKTEI 8580
Query: 1331 IQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSL-KAELHLQAQ 1155
+L + ++ L+D S + + + ++ N +E++ RSL + LQ
Sbjct: 8581 ADKLLQDANSESDRLKDLSMK-------LQMQRQDIEKTNTEMETKKRSLDRMSRELQDD 8633
Query: 1154 KAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIE 975
K +++ +R+ E + L + E L ++E++DLE L+ E E+A DIE
Sbjct: 8634 K-IRLKNDRDAYEKDMTHLELKREEL---VRETEDLERKILQQRE-----QDEMAKRDIE 8684
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGN 795
+ A E +M++ +++ RNE AK E +NV R + + + +
Sbjct: 8685 NQTEALE-VMKV--DILKKRNEFAK------------EMENVHSERQKLLLLQGALQSQE 8729
Query: 794 GRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQ 615
R F +++ +C + + AEM ET + E + +EE+Q
Sbjct: 8730 SELENRVFMEEQKHLKQAKAETEECRK---------QLAEMSETVTTEQNEYRKLIEELQ 8780
Query: 614 QTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEIN 447
+ + ++ KK+ ++S ++ +L S +H + + E N
Sbjct: 8781 REKEQL-------EISKNQIEQEKKDLQNMKSNLERQL---ESLRHEKANVEDEKN 8826
Score = 76.3 bits (186), Expect = 6e-11
Identities = 85/437 (19%), Positives = 201/437 (45%), Gaps = 27/437 (6%)
Frame = -1
Query: 2279 EEKQHTIELQENFNALRQKN-EDICLKIEANNNLLEQKDNIIVELSHKL-----QENEEQ 2118
E ++H +E ++ +QK EDI I++ ++LE++ + + +LSH L +E EE
Sbjct: 13481 EAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEEL 13540
Query: 2117 RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEAL------SMAVDDRAFME 1956
L+ + +E + ++E++ + R+ R ++ LKE + ++ D+ ++
Sbjct: 13541 ERLLEKERDDIENCKKIIESEKQSIERE----RAELKRLKEEVEVQHERTLLQQDKNMIQ 13596
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIE 1776
K+ + LE +K ++E+ ++ +S+L L+++ E+ + + E
Sbjct: 13597 KEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQE---------------E 13641
Query: 1775 KLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILK---QDINIE---DE 1614
+L+G + ++E+ L K+ D+ + K ++ Q+ LK +D + DE
Sbjct: 13642 ELHGLPEEIEIEDHLKKED-----DVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDE 13696
Query: 1613 LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
+ +T E + A + + AK ++++ + +V +++ + I L ++
Sbjct: 13697 ITKTDERRQRALEETVATT---AKQPIVIKLEDTLTSEVQEMRDHLNNEIKELARMKTIM 13753
Query: 1433 QVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKEL 1254
++ +Q++ KS++ + E + + E + L++L + L + + KE+
Sbjct: 13754 KMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLDKKNKEI 13813
Query: 1253 WN---------AKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNV 1101
N A+ V+ K +N L+ + Q ++ +IQ + +V +E +
Sbjct: 13814 ENNTETFLKKIAQLETTIVLMKKDKENIENELLQLK---QIEQEREIQRKADVTSTEKEM 13870
Query: 1100 LSSEVENLKSELKESKD 1050
+ +V K+EL++SK+
Sbjct: 13871 YTEKV-TYKTELEDSKE 13886
Score = 75.5 bits (184), Expect = 1e-10
Identities = 134/627 (21%), Positives = 266/627 (42%), Gaps = 97/627 (15%)
Frame = -1
Query: 2189 NNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDV 2010
N LE + E+ ++ + E+ R +L DMQ +EQM + E+EE+ Q + ++
Sbjct: 2011 NRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEK 2070
Query: 2009 NHLKEALSMAVDDR------AFMEKQ-LQD--LENQKETVS-KELALSVSREQKLASDLK 1860
+ L+ L +D EKQ L+D +E QKE +A R+++ ++
Sbjct: 2071 DKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIR 2130
Query: 1859 ALSEKEEST--------KNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIY 1704
EK+E T + + I Q + ++ +I+ + Q E + E+I
Sbjct: 2131 VGIEKQEITFKDLKADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLVEEIE 2190
Query: 1703 DLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKV---SG 1533
K L EV +++ + + +E E ++ +E + K+ N+ A++ S
Sbjct: 2191 KRTKALDEMQMEVDKERQEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESD 2250
Query: 1532 ILEML---LPMKDDVFSLKEEVLG-----------NINSLRNDAQMVQVALEQMQDTKSE 1395
LE+ + + +F L++E LG I+ L+N +M +V +EQMQ K +
Sbjct: 2251 NLELQSENISKERTIFELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQ 2310
Query: 1394 LFAEAEI--------------RAQEVLRLQAEVDAIQ----HI-----LIELKRKNQTLQ 1284
+AE + QE+ L+ E + ++ H+ L E + K+ ++
Sbjct: 2311 QRKKAEYVKTARGRETTALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEME 2370
Query: 1283 DESQRNAKELWNAK-----------ARLNNVMSKNINLESQN-RSLKAELHLQA----QK 1152
+E+ + KE + + + M + +E++N K EL +Q +
Sbjct: 2371 NEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTE 2430
Query: 1151 AFQIQEERNVVE-SEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIE 975
+ ++ ++ VVE S+ + L + + ++L E + + +++ + + Q + +
Sbjct: 2431 TYMLETQKPVVEKSKTDELDEVRKKINADLSEVEKQKSALVQM-NLKISQEESYVKKEKD 2489
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGN 795
+ E + + +L +NE + +A E E +NV R E V I+K
Sbjct: 2490 RLKLQENEQNMQMSQLNAKQNELD--ERQAEMEKQKRELENVM-DRLEKEKVEITKE--K 2544
Query: 794 GRANQREFQNKEEDSSGVDLLKNKCTR-----------LEFQVQKLSEK----AEMFETK 660
R N+ + + K +++S VDL+K + R L +++K+ EK AE FE
Sbjct: 2545 QRVNEMQNEVKRKNAS-VDLIKQEVLREQDHIENSREILNRELEKIKEKKTILAEEFEAL 2603
Query: 659 -------SREAQQMANKLEEMQQTLSD 600
+E Q++ E+Q+ D
Sbjct: 2604 DDKKEMIGKEMQRLGKMKAELQKEAED 2630
Score = 75.5 bits (184), Expect = 1e-10
Identities = 144/718 (20%), Positives = 298/718 (41%), Gaps = 33/718 (4%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQE-N 2127
K + +L +E + +L N + + N D L I+ + LE+ I +L K ++ +
Sbjct: 13102 KTLKQLKDENESKRTQLD---NTIEKMNMDK-LSIQREKDSLEE---IKADLQRKAEKLD 13154
Query: 2126 EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL 1947
EE R A+Q Q +++ +L DD +E SM RA +E+Q
Sbjct: 13155 EEMRKAVQITSQ---------------ISQDAKILDDDREKEEELRSM----RADIERQA 13195
Query: 1946 QDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLY 1767
+ LE+ + + E + + K +DL +++ +N L +Q EL EK
Sbjct: 13196 KILESDVQLLQTE--KEILEKSKTENDLLREDLEKQRKRNDLTLQ-------ELRKEK-- 13244
Query: 1766 GSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGR 1587
+ ++QM + K+ + + L ++ K E++ ++ + +Q + D+L E+ +
Sbjct: 13245 --MALEQMITDITKE-KDAVASLQNEVSLKQHELKNKETELDEQRKEM-DDLRMQLEMRQ 13300
Query: 1586 SATDMKKVNSDA----GAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALE 1419
++T+ ++ D K+ LE + + D+ ++ + +N +
Sbjct: 13301 NSTNKQQQEVDVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAV 13360
Query: 1418 QMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKA 1239
Q D + + + + V + + E+D + +I+ K + Q+L E + +E+ +A
Sbjct: 13361 QQTDELEKFTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRA 13420
Query: 1238 RLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKE 1059
++ ++ +L + +K + + Q A + E++ VE + N+ + +N EL+
Sbjct: 13421 QIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNL--QKQKNELEELRN 13478
Query: 1058 SKDLEGYFLRLFEILLG---QHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNE 888
+ + E + + +I+L + VE I+S R EK L++L + NE + + E
Sbjct: 13479 TIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQE 13538
Query: 887 ALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLE 708
L + ER ++ + S +S+ RA + + + E LL+ ++
Sbjct: 13539 ELERLLEKERDDIENCKKIIESE--KQSIERERAELKRLKEEVEVQHERTLLQQDKNMIQ 13596
Query: 707 FQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVR-------- 552
EK + K+R +++ N EE+++ S++
Sbjct: 13597 ------KEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQEEELHGLPEEI 13650
Query: 551 ----SLKKENTRLRSEM--KGELTPSRSFKHREGS-------FIKEINIGDEDDTPLIQX 411
LKKE+ LR E+ K + S+ F+ + S + EI DE ++
Sbjct: 13651 EIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRALEE 13710
Query: 410 XXXXXXXXXXKI---DTRTSETQEIDTLMDDNRKYWNRVSHFTK-QTQSLQNSVQELQ 249
I DT TSE QE+ +++ K R+ K + L+ + ++Q
Sbjct: 13711 TVATTAKQPIVIKLEDTLTSEVQEMRDHLNNEIKELARMKTIMKMEKDQLKQAKSDIQ 13768
Score = 75.1 bits (183), Expect = 1e-10
Identities = 109/585 (18%), Positives = 249/585 (42%), Gaps = 36/585 (6%)
Frame = -1
Query: 2156 VELSHKLQENEEQ-RSALQNDMQSVE-QMHAVSQ--TEREELNRQLVLLRDDVNHLKEAL 1989
+E KL E +Q R+ + N Q ++ Q +++ TE+ +L R + ++ +++H++E +
Sbjct: 145 IEQIEKLWEGTKQERTEIDNMKQKIQRQQDEITRMTTEKGQLERTITHMKAEIDHIRERM 204
Query: 1988 SMAVD----DRAFMEKQLQDLENQKETVSKELALSVSREQKL-------ASDLKALSEKE 1842
+ +R +E+ DL+ ++ ++ ++ ++ Q L + L
Sbjct: 205 DRNKEEVNRERERVEQMRSDLQAEQSSLQQKRDEIMTERQNLEMIRYETLRQQEELESNR 264
Query: 1841 ESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQ 1662
ESTK+++ + ++++I ++ + Q L++ +I D L K +++
Sbjct: 265 ESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLMEQMKAEIEDEKNELEKKKEDIK 324
Query: 1661 GQQEGILKQDINIEDELARTK-EVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLK 1485
Q++ Q I+ +L + K E+ + + +K + A + E L ++D++ ++
Sbjct: 325 RQRD----QFEQIKLDLQQVKMEMEQRWHETEKEGLEQRAVIQREKEQLKYLQDEIQRVR 380
Query: 1484 EEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELK 1305
EEV N R ++ + Q++ E E + ++LR + +++ ++H E++
Sbjct: 381 EEVERN----REFSKQEHARISQLRAQALEENNLIENKWHDILRKEKDLEEMKH---EIE 433
Query: 1304 RKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERN 1125
R + L + KE + ++ S I++E + +K E ++Q +++
Sbjct: 434 RGREELVMNGELVKKEWEKIEQAKVDIQSHMISMEGRVDEIKRETERLKHIKTEMQRDKD 493
Query: 1124 VVESE---------------HNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVA 990
+E + + +++ E+E+ +E +LE + + + ++
Sbjct: 494 ALEKQKDDTRKAKEEAERKRYEIVTEELEHRARLQRERDELENIRAEMQRVNDVEKAKIL 553
Query: 989 SLDIESCRFAEE-KLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLI 813
ES R EE + R EL+ NA++K E ER N R E M +
Sbjct: 554 KEKEESIRIREEARQERETTELV-----NAEIKAEK-------ERLN---QRQEEM---L 595
Query: 812 SKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMAN 633
+ R + KEE + D+ + ++E ++ + E E K E Q+
Sbjct: 596 RERQEIERIKHETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKE 655
Query: 632 KLE----EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK 510
++E E+++ D+ + L+ E R++ EM+
Sbjct: 656 QMEEAKVELEEEREDLERKRDLVSREIEQAEFLRNEILRVKEEME 700
Score = 75.1 bits (183), Expect = 1e-10
Identities = 143/796 (17%), Positives = 329/796 (41%), Gaps = 40/796 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNL--LEQKDNIIVELSHKLQEN 2127
E+ R+ E ++ T +Q + ++ D+ K N + L Q+ +++ +
Sbjct: 7418 ELERIKTESQRATEHMQSH---AEERAGDLGEKEPVNTRIQRLIQEAEKASKMAWSTKHE 7474
Query: 2126 EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL 1947
E R +Q ++ SVE+ ER++++ + + ++ H +E L D+ K+
Sbjct: 7475 PEMR--MQREV-SVEE----ESVERQDMSANMQRMILEIEHARETLRGMKDEVQAARKER 7527
Query: 1946 QDLENQK-ETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQN----KQLELE 1782
+LEN K E ++ + + + EQ+ + + EK++ +++L+ E+N + +LE
Sbjct: 7528 SELENMKLEFLTMKKNMEKTYEQQ---NDEIQKEKQQIESSKMLLSRERNDLEQNRADLE 7584
Query: 1781 IEKLYGSLQMKQM--ENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELA 1608
+K +L +++ EN LL+ + + + L + E ++ Q + E
Sbjct: 7585 RQKQIMALDKQKLLAENELLEREKADVIKIIENLESLREEATRERATETAQATRRDSEEL 7644
Query: 1607 RTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQV 1428
K S D ++ + + ++ ++ L+ +K D+ + E+ L+ QM +
Sbjct: 7645 MQKMEALSMEDFQEASKNQMVELKRQIDKLIELKADLLQQQTELKKTKADLKQ--QMDDL 7702
Query: 1427 ALEQMQDTKSELFAEAEIRAQEVLRLQAEVD----AIQHILIELKRKNQTLQDESQRNAK 1260
+ + K E +++ R E++ +Q + D IQ + +E KR + L+ E K
Sbjct: 7703 EKTRSEILKHEKDTDSKTRELELIEIQRQKDDLETRIQKLTLE-KRDLEVLRSEIVLEKK 7761
Query: 1259 ELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVEN 1080
+L ++ + + S + E++ + Q+ ++ + +L N
Sbjct: 7762 DLDQKMKQVIRKRDEMEKIRSDIANATEEINRERQELEILRNNVQSARHDFELLLERTAN 7821
Query: 1079 LKSELKESKDLEGYFLRLFEIL---------LGQHVEVASLDIESCRFAEEKLMRILDEL 927
L+ E + D+E L + +I + + +E + ++I+ + ++ R + ++
Sbjct: 7822 LEDEESAATDIERLVLEVVKIREMVRNLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDI 7881
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRA---------EAMSVLISKSLGNGRANQRE 774
+R L E E +++ + RA E+M ++ K + E
Sbjct: 7882 GQIRENLGGLGEE--IEKTRRDKRELEKMRAELAEKQQEQESMREMLHKEREELEQLKDE 7939
Query: 773 FQNKEED----SSGVDLLKNKCTRLEF-QVQKLSEK----AEMFETKSREAQQMANKLEE 621
++ED V+ + +K EF +QK E+ E TK R+ Q+ + +++
Sbjct: 7940 INREKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNSDVQD 7999
Query: 620 MQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIG 441
++QT+ ++ + K+ +L + K EL +E +I E I
Sbjct: 8000 LRQTIEEINIQHGKKRAELEGIGFELKKGEQLLEKQKDEL--------KENGWIVE-EIK 8050
Query: 440 DEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSV 261
++ D+ ++ +D + ++ MD R S +Q + L+ S+
Sbjct: 8051 NKKDS--LEKINMEILRKNEDMDKEKGKLRQEKQEMDLFR------SELQRQREDLETSI 8102
Query: 260 QELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAW 81
Q+L + + I + K+L+ + Q++ ++ K F
Sbjct: 8103 QKLTHEKREME------------VLRSEIVLEKKDLDQKMKQVIRKRDEME---KIRFDI 8147
Query: 80 ANSMHDLNGQEQKLKV 33
AN+ +++G+ Q+L++
Sbjct: 8148 ANARVEIDGERQELEI 8163
Score = 75.1 bits (183), Expect = 1e-10
Identities = 126/646 (19%), Positives = 248/646 (38%), Gaps = 31/646 (4%)
Frame = -1
Query: 2279 EEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQN 2100
EEK +L + + E I K + +EQ EL ++Q E+Q +Q+
Sbjct: 9119 EEKNEMADLSRELQKAKDELEKIAYKTNKERHEVEQMQ---AELHSQIQAIEQQGQIMQD 9175
Query: 2099 DMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKET 1920
+E+ Q + EE+ + + HL L + +E D+E K+
Sbjct: 9176 KQNHLEEKELSIQRKEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQK 9235
Query: 1919 VSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQME 1740
+K+ L +L ++ L E K+ + +Q ++ ++ + +EK+ LQ
Sbjct: 9236 NNKDFELLEKIRSELENEKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQ----- 9290
Query: 1739 NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDIN-IEDELARTKEVGRSATDMKKV 1563
S+ Q ++E K D+N + E+ R K+V D K+
Sbjct: 9291 ---------------------SKREQTEKE---KADLNRVNAEIQREKQV----IDKKRH 9322
Query: 1562 NSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAE 1383
++ +E L +K ++ +E++ L + +VQ+ E + E+ +
Sbjct: 9323 MTNRA------MEELETIKTELKERQEKIQTEQEKLEEEKLLVQIEAENLNKVLEEIKRQ 9376
Query: 1382 AEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRN----------AKELWNAKARL 1233
E L+ + ++ E +RK ++++ Q N K++ K L
Sbjct: 9377 QEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQKQEL 9436
Query: 1232 N--------NVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEH---------- 1107
+++ N+E RSL E L QKA +I +R+ +E E
Sbjct: 9437 QKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNKL 9496
Query: 1106 NVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL 927
+VL +E++N ++E K +++ R K + L+E
Sbjct: 9497 DVLQNEMQNENKAMEEIK----------------------YELDGKRNEINKEQQRLEES 9534
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSS 747
+ NE K + DYE++ + E M V + + + KE D
Sbjct: 9535 LRAINEE---KGDLEIMRADYEKQE---QQIEEMRV------------EAKMERKELDQI 9576
Query: 746 GVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXX 567
+L K+K T ++++ +KL+ M E + + ++M ++L +Q + D
Sbjct: 9577 KSELEKDK-TEIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKE 9635
Query: 566 XIRVRSLKKENTRLRSEMKGELTPSRS-FK-HREGSFIKEINIGDE 435
+ ++N + + E+ R+ FK +E ++ NI DE
Sbjct: 9636 ANTEKDKIEKNKEIVERLMAEVEEQRNDFKLKKEELALERQNIVDE 9681
Score = 75.1 bits (183), Expect = 1e-10
Identities = 118/636 (18%), Positives = 280/636 (44%), Gaps = 27/636 (4%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLE-QKDNIIVELSHKLQEN 2127
KE S L + +Q +E + + ++ E + ++E + ++ QK+ + +E E
Sbjct: 9915 KERSELDNKIQQTDLE-KHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDIERQKIADEQ 9973
Query: 2126 E---EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFME 1956
+ + +S LQN+ + + ++ V + ERE L KE + ++ M+
Sbjct: 9974 DLLIQNKSELQNENERIRNINEVIKKERETL--------------KEMEAHLEKEKEEMK 10019
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIE 1776
++ QKE + K + Q L L +++E ++ ++ + + ++
Sbjct: 10020 SITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQVS 10079
Query: 1775 K-----LYGSLQMKQMENTLLKDGNEKIYDL---CKLLATKSREVQGQQEGILKQDINIE 1620
K L +MK+ E L++ +I ++ +L K + + ++E ++ + ++
Sbjct: 10080 KQKEEDLTKQKEMKE-ERKSLEETKARIIEMKTKAELEDIKKEKEKEEEEEEMRVKVEMD 10138
Query: 1619 DELARTKEVGRSATDMKKVNSDAG---AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRN 1449
KE+ R +++K+ S+ K++ +++ K ++ +K E++ +
Sbjct: 10139 G-----KELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKSEIMKQRQQMEE 10193
Query: 1448 DAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQ- 1272
+ ++ ++Q K ++ EI + ++ ++ + IQ EL + Q + DE
Sbjct: 10194 ERSELENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDL 10253
Query: 1271 --RNAKELWNAKARLNNVMSKNINLESQNRSLK-AELHLQAQKAFQIQEERNVVESEHNV 1101
+N EL N R+ N+ N ++ + +LK E HL+ +K EE V E
Sbjct: 10254 LIQNKSELQNENERIRNL---NEIIKKERETLKEMEAHLEKKK-----EEIKSVSEETRR 10305
Query: 1100 LSSEVENLKSEL-KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL- 927
L ++E + +++ K++KD L+ Q ++ + E ++L + +DE
Sbjct: 10306 LKEDLEKMSTDVNKQNKD-----------LMNQR-DLLEQEREEINHKWKQLQQRIDEFD 10353
Query: 926 --ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEED 753
+ + E K + + E +RK++ ++A + + +K+ ++E +N+EE+
Sbjct: 10354 AQVSKQKEQDLPKEKGMKE----DRKSLEETKANVIE-MKTKAEPEEIKKEKEKENEEEE 10408
Query: 752 SSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXX 573
E +V +E+ E+++ KS E +++ ++++ Q+ L+D
Sbjct: 10409 EE----------EEEIRVIVETERKELYQIKS-ELERVRSEIDHEQKKLNDYMKMIEQEK 10457
Query: 572 XXXIRVRS-LKKENTRL---RSEMKGELTPSRSFKH 477
+++S + K+ ++ RSE+ ++ + KH
Sbjct: 10458 EDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKH 10493
Score = 74.3 bits (181), Expect = 2e-10
Identities = 113/597 (18%), Positives = 256/597 (42%), Gaps = 32/597 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNL------LEQKDNIIVELSHK 2139
E RL + +++ E QE R K+E + K E N+ E+ + + E+ +
Sbjct: 583 EKERLNQRQEEMLRERQE---IERIKHETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQ 639
Query: 2138 LQENEEQRSALQNDMQSVEQMHAVSQTEREELNR----------QLVLLRDDVNHLKEAL 1989
+++ E++ +Q + +E+ + ERE+L R Q LR+++ +KE +
Sbjct: 640 IEDIEKKVEEIQKTKEQMEEAKVELEEEREDLERKRDLVSREIEQAEFLRNEILRVKEEM 699
Query: 1988 SMA--------VDDRAFMEKQLQDLEN-QKETVSKELALSVSREQKLA--SDLKALSEKE 1842
V+ RA + +L+ LE ++ET + + S+ + + L L +
Sbjct: 700 ESRWRETETEEVELRAKTQHELERLEKLREETERSQKNIEESKIELMLWKESLDKLKGEM 759
Query: 1841 ESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQ 1662
E K+ +++Q + K E ++ + L++++ E T+ ++ ++ D + + +
Sbjct: 760 EEDKHVVIMQMNEAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQH 819
Query: 1661 GQQEGILKQDINIEDELARTKEVGRSATDM--KKVNSDAGAKVSGILEMLLPMKDDVFSL 1488
+ E + +N E E A ++ +M KK ++ + ++ L +D++
Sbjct: 820 AEMEDWFRV-VNKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKK 878
Query: 1487 KEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIEL 1308
EE + + + Q + LE+M+ + E + ++ + + V+ ++ L++
Sbjct: 879 AEE----LEQINKEIQRARQELEKMRYFEKESLQKM---LEDTQQERVFVEQVRSELLKN 931
Query: 1307 KRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEER 1128
K E KEL + ++ N + +LE + + + +++ Q+Q ++
Sbjct: 932 KADQDKCLFEMDSERKELEQMRFQVEN---EKKDLEQRRYEM---MRYDVEQSAQVQRQK 985
Query: 1127 NVVESEHNVLSSEVENL-KSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEK 951
+E + L + E++ +S +D E L + EI + E + +E + EE
Sbjct: 986 EELEKIKSQLVIDTESMNRSRELARQDREKAELLIVEIQ--EQREDVNKRLEETKQREEA 1043
Query: 950 LMRILDELICLRNENAKLKNEALYEYHDYE--RKNVSGSRAEAMSVLISKSLGNGRANQR 777
L + ++ R + K++ E L YE ++ ++ RAE + G+ ++
Sbjct: 1044 LRLLRKDMENEREDLEKIRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREK 1103
Query: 776 EFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTL 606
KEE ++ +K + +E +L+++ E + K A+ LE M+ L
Sbjct: 1104 INHEKEEMIRKMEAMKREMGEIEDMKVELTKQKENIDMKMEHARLEMTNLEMMKADL 1160
Score = 71.6 bits (174), Expect = 1e-09
Identities = 115/638 (18%), Positives = 266/638 (41%), Gaps = 70/638 (10%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDI-----------CLKIEANNNL------LE 2175
+E++ L EE K+ + E++ +R++ E I + N N+ ++
Sbjct: 6332 EEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQ 6391
Query: 2174 QKDNIIVELSHKLQEN----EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVN 2007
QK N + ++S ++ + E+++ +Q + +E+MH Q ++E + L + D+
Sbjct: 6392 QKRNALEKMSKEISRDRMKLEDEKKEIQLAREELERMHGDMQRQQEAKDHLLSGITDESL 6451
Query: 2006 HLKEALSMAVD----DRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKA------ 1857
K + + D+A ++ + ++ K+ V + + + L D ++
Sbjct: 6452 LKKSEAEIVLQPSQVDKAKPARKTEISDSDKQPVFVQQMPEMDLKDALKKDFESEKLDLP 6511
Query: 1856 -----LSEKEESTKNQLLIQTEQNK--QLELEIEKLYGSLQMKQMENTLLKDGNEKIYDL 1698
L + ++ Q LI+ E +K Q+ E++K ++ K+ + +++ +K+ D+
Sbjct: 6512 KVKDVLPQDQQMKLEQKLIEDEMDKLKQMRAELQKEADQIEKKKQD---MQNERQKLDDM 6568
Query: 1697 CKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEML 1518
L + R + E I Q +N + + + TD +++ ++ + +
Sbjct: 6569 AARLQEERRTNERLNEEINIQKVNQQKQATAFQ---MEKTDFERIKTEIDQANKELADQQ 6625
Query: 1517 LPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEV 1338
K + +++E N ++ V+ + + S A+++ +++L+ Q E+
Sbjct: 6626 EKNKKTITEMQKERETLEEMRANISKQVETITNENKSLSSRESELAKLQ-EDILQQQQEM 6684
Query: 1337 DAIQH-ILIELKRKNQT----------LQDESQRNAKELWNAKARLNNVMSKNINLESQN 1191
D +++ I++E+ + +Q + D E+ N + V+++ N++S
Sbjct: 6685 DELKNTIMMEMCQLDQRQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQTRNIKSDM 6744
Query: 1190 RSLKAELHLQAQKAFQIQEERNVVESEHNVLSS--------------EVENLKSELK--- 1062
SLK E Q ++ EE++++E E +L+ E+ENLK E +
Sbjct: 6745 VSLKMEKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIK 6804
Query: 1061 -ESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL-ICLRNENAKLKNE 888
E K+LE + L +G E + + EE + +L I R K E
Sbjct: 6805 NEKKELEKMKISLQRKAIG-FKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEE 6863
Query: 887 ALYEYHDYERKN-VSGSRAEAMSVLISKSLGNGRANQRE-FQNKEEDSSGVDLLKNKCTR 714
L + RK + + + K+ ++ E ++ + E + + LK T
Sbjct: 6864 RLDQTEKKRRKTYYTEDLFQEEKTDLQKTKEEINYDREEIYRQRTELNKEKETLKQMHTS 6923
Query: 713 LEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSD 600
+++ + ++ E + E Q+ +L+ Q+ + D
Sbjct: 6924 NLKEIENIEKEKEKIQRTWNELDQIRAELQNKQRDMDD 6961
Score = 70.9 bits (172), Expect = 2e-09
Identities = 128/646 (19%), Positives = 260/646 (40%), Gaps = 99/646 (15%)
Frame = -1
Query: 2258 ELQENFNALRQ-----KNEDICLKIEANNNLLEQKD--NIIVELSHKLQENEEQRSALQN 2100
ELQ +R KNE LK + ++K+ +II E S + ++ E+ + +
Sbjct: 9691 ELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNV 9750
Query: 2099 DMQSVEQMHAVSQTEREELNRQLVLLRDDVNH-------------------------LKE 1995
Q ++ + EREE+N + + ++ L+E
Sbjct: 9751 QKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEE 9810
Query: 1994 ALSMAVDDRAFME-------KQLQDLENQKETVSKE--------LALSVSRE-------- 1884
++ + E +++++L+ +E + KE + L + RE
Sbjct: 9811 VNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSE 9870
Query: 1883 ------------QKLASDLKAL-SEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQM 1743
+KL D+K + EKE+ K + I T Q +++E E +L +Q +
Sbjct: 9871 LVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMT-QKQEMEKERSELDNKIQQTDL 9929
Query: 1742 ENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDE----LARTKEVGRSATD 1575
E ++ E + L + + E+Q Q+E + + I DE + E+
Sbjct: 9930 EKHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDIERQKIADEQDLLIQNKSELQNENER 9989
Query: 1574 MKKVNSDAGAKVSGILEM---LLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDT 1404
++ +N + + EM L K+++ S+ EE L + ++ + +
Sbjct: 9990 IRNINEVIKKERETLKEMEAHLEKEKEEMKSITEETRRQKEDLEKMSTDIKEQNQDLMKQ 10049
Query: 1403 KSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNV 1224
+ L E E E +LQ +D + + K ++ T Q E + K L KAR+ +
Sbjct: 10050 RDLLEQEKEDINHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEM 10109
Query: 1223 MSK----NINLESQNRSLKAELHLQAQK--------AFQIQEERNVVESEHNVLSSE--- 1089
+K +I E + + E+ ++ + +++ ER+ ++ E L+ +
Sbjct: 10110 KTKAELEDIKKEKEKEEEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKI 10169
Query: 1088 -------VENLKSE-LKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILD 933
+E +KSE +K+ + +E L + ++E DIE+ + +KLM ++
Sbjct: 10170 IEQEKQNLEKMKSEIMKQRQQMEEERSELENKIKQTYIE--KCDIENSKEIVQKLMVEVE 10227
Query: 932 ELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEED 753
E + + + E L D ER+ + A+ +LI N+ E QN+ E
Sbjct: 10228 E----QKHEIQFQKEEL----DIERQKI----ADEQDLLIQ--------NKSELQNENER 10267
Query: 752 SSGV-DLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEM 618
+ +++K + L+ L +K E ++ S E +++ LE+M
Sbjct: 10268 IRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRLKEDLEKM 10313
Score = 70.1 bits (170), Expect = 4e-09
Identities = 121/594 (20%), Positives = 247/594 (41%), Gaps = 45/594 (7%)
Frame = -1
Query: 2258 ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQ 2079
+++EN L ++ IE + + + EL+ K QE E R L + + +EQ
Sbjct: 7883 QIRENLGGLGEE-------IEKTRRDKRELEKMRAELAEKQQEQESMREMLHKEREELEQ 7935
Query: 2078 MHAVSQTERE--ELNRQLV----------------LLRDDVNHLKEALSMAVDDRAFMEK 1953
+ E+E E+ R+LV ++++ + E L D +
Sbjct: 7936 LKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNS 7995
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEK 1773
+QDL E ++ + + + + +LK + E K++L ++N + EI+
Sbjct: 7996 DVQDLRQTIEEINIQHGKKRAELEGIGFELKKGEQLLEKQKDEL----KENGWIVEEIKN 8051
Query: 1772 LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSR------EVQGQQEGILKQDINIEDEL 1611
SL+ ME +L+ + + KL K E+Q Q+E L+ I
Sbjct: 8052 KKDSLEKINME--ILRKNEDMDKEKGKLRQEKQEMDLFRSELQRQRED-LETSIQKLTHE 8108
Query: 1610 ARTKEVGRSATDMKKVNSDAGAK-VSGILEMLLPMKDDVFSLKEEVLG---NINSLRNDA 1443
R EV RS ++K + D K V + + ++ D+ + + E+ G + LR++
Sbjct: 8109 KREMEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRFDIANARVEIDGERQELEILRDNV 8168
Query: 1442 QMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNA 1263
Q + E++ + + L E E A ++ RL EV I+ ++ LK + + +ES+
Sbjct: 8169 QSARQDFERLVERTANLEVE-ESAATDIERLVLEVVKIREMVRNLKGEMERRMEESKVEI 8227
Query: 1262 KELWNAKARLNNVMSKNINLESQNRSLKAEL--------HLQAQKAFQIQEERNVVESEH 1107
E K+ + ++ + LK E+ +L+ KA +++E++ ES
Sbjct: 8228 DEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKA-ELEEKQQEEESMR 8286
Query: 1106 NVL---SSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRIL 936
+L E+E LK ++ K+ L E + + D++ + E+L +
Sbjct: 8287 EILQKEKEELEQLKKDINREKEDIEISRELVESEIYEGEVKGFTDVQKYK---EELQIVT 8343
Query: 935 DELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEE 756
+EL+ + +L ++ + E ++ + +A I+ + R E Q K+
Sbjct: 8344 EELLTKKRNLEQLNSDVQHLMQTLEEVDIQYIKKKAELEHITSEI-QKREQILEKQKKKL 8402
Query: 755 DSSG-----VDLLKNKCTRLEFQV-QKLSEKAEMFETKSREAQQMANKLEEMQQ 612
+ +G ++++K + ++ QK + + E RE Q+ E+Q+
Sbjct: 8403 EENGWIIEEIEMMKVTLESINMEILQKREDMEKEKENLRREKQETELFRGELQR 8456
Score = 69.3 bits (168), Expect = 7e-09
Identities = 125/585 (21%), Positives = 244/585 (41%), Gaps = 25/585 (4%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEE 2121
EVS E K EL E R++ +D+ +++E N ++ E+ + EN +
Sbjct: 13267 EVSLKQHELKNKETELDEQ----RKEMDDLRMQLEMRQNSTNKQQQ---EVDVFIVENMK 13319
Query: 2120 QRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQD 1941
R ND++S M + ER +L + D N L + + AV +EK D
Sbjct: 13320 MR----NDLES---MKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTD 13372
Query: 1940 LENQKETVSKEL-ALSVSREQ--KLASDLKALSEKEESTKNQLLIQTEQNKQLE-LEIEK 1773
++ +KE V KE + V ++ K +L++L+ + E K ++ + Q + LE L +
Sbjct: 13373 IKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADL 13432
Query: 1772 LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEV 1593
L G+ +K + T + E K EV+ Q L++ N +EL T E
Sbjct: 13433 LAGADDIKTLVQTEKQMAIED--------TEKKTEVELQMN--LQKQKNELEELRNTIEA 13482
Query: 1592 GRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRND-AQMVQVALEQ 1416
+ + +K+ D K + ++ + DV ++ L ++ + N+ Q Q LE+
Sbjct: 13483 EKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELER 13542
Query: 1415 MQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKAR 1236
+ L+ E D I++ ++ + Q++ +R EL K
Sbjct: 13543 L--------------------LEKERDDIENCKKIIESEKQSI----ERERAELKRLKEE 13578
Query: 1235 LNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVE------SEHNVLSSEVENLK 1074
+ + + + +N K + HL+ +KA +E N+ E SE ++L+ E+E +
Sbjct: 13579 VEVQHERTLLQQDKNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKR 13638
Query: 1073 SE-----LKESKDLEGYFLRLFEILLGQHVEVASLDIE-------SCRFAEEKLMRILDE 930
E L E ++E + + ++L + ++ D + R AE + LDE
Sbjct: 13639 QEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTS--LDE 13696
Query: 929 LICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKE--E 756
+ + + + AL E V+ + + + + + +L + R+ N E E
Sbjct: 13697 I----TKTDERRQRALEE-------TVATTAKQPIVIKLEDTLTSEVQEMRDHLNNEIKE 13745
Query: 755 DSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEE 621
+ ++K + +L+ + + E FE EA + ++ EE
Sbjct: 13746 LARMKTIMKMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNEE 13790
Score = 69.3 bits (168), Expect = 7e-09
Identities = 86/415 (20%), Positives = 173/415 (41%), Gaps = 36/415 (8%)
Frame = -1
Query: 2180 LEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHL 2001
++Q H +++EE+ SA + +V ++ +E +E+ L +DV +
Sbjct: 14374 IQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVARM 14433
Query: 2000 KEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQL 1821
K + M D +E+ D++ Q E + + ++ + + L L+ +E N L
Sbjct: 14434 KTIMKMEKDQ---LEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTL 14490
Query: 1820 LIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKI-YDLCKLLAT-KSREVQ----- 1662
++NK++E E + + L+K E I +L +L T + RE+Q
Sbjct: 14491 ---DKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQEREIQRGTDD 14547
Query: 1661 -GQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDA-GAKVSGILEM---------LL 1515
+ + + + EL KE + D +DA AK G E +L
Sbjct: 14548 TSNEREKYDEKVTYKTELEDNKEKKKPDRDSSLKLTDADSAKTDGEREAQTLETKVQDVL 14607
Query: 1514 PMKDDVFSLKEE----------VLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQ 1365
+ DD +EE ++ +N + D Q ++ ++ KS + E R
Sbjct: 14608 QLTDDTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEKCRSAEEEKSVIMESLERRRN 14667
Query: 1364 EVLRLQAEV----DAIQHILIELKRKNQTLQDESQRNAKEL---WNAKARLNNVMSKNIN 1206
+ ++Q+EV I+H L ++K + Q ++ + QR + + W ++ +
Sbjct: 14668 SLEKVQSEVLTLTQEIEH-LAQIKTEMQQIETKMQRQTRSVATQWETDVQIQQEGQEATE 14726
Query: 1205 LESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-KESKDLE 1044
+ + K+E + A+K ++ V + L+SEV+ ++ L KE +D+E
Sbjct: 14727 TRG-HITKKSEEEISAKKT-----KQPTVTKLEDTLTSEVQEMRDSLNKEMEDVE 14775
Score = 68.9 bits (167), Expect = 9e-09
Identities = 119/605 (19%), Positives = 261/605 (43%), Gaps = 46/605 (7%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQ 2103
E E + +E Q++ + + E+ ++ + + + N +L +LQ +EQ +
Sbjct: 8731 ELENRVFMEEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQREKEQLEISK 8790
Query: 2102 NDMQSVEQMHAVSQTEREELNRQLVLLR-------DDVNHLKEALSMAVDDRAFMEKQLQ 1944
N +EQ Q + L RQL LR D+ N L++ S + + + + K+ +
Sbjct: 8791 NQ---IEQEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKERE 8847
Query: 1943 DLEN-------QKETVSKEL-ALSVSREQ--KLASDLKALSEKEESTKNQLLIQTEQNKQ 1794
DLEN +K+ + +E L + RE+ K+ S+L+ E ES + ++ + E+ Q
Sbjct: 8848 DLENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINNKMEELLQ 8907
Query: 1793 LEL-------EIEKLYGSLQ--MKQMENTL--LKDGNEKIYDLCKL-LATKSREVQGQQE 1650
+++ EIEK LQ +EN ++ +K D+ + + K RE++ Q +
Sbjct: 8908 MKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQLD 8967
Query: 1649 GILKQDINIEDEL-ARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVL 1473
K+ + +E+ + K++ DMK+ + G+LE K ++ K+E+
Sbjct: 8968 ---KETKRLSEEIELKVKDLEMEMADMKRQKQEI-EDTKGLLE---KEKQELKQEKKELE 9020
Query: 1472 GNINSLRNDAQMVQVALEQMQDTKS---ELFAEAEIRAQEVLRLQAEVDAIQHILIELKR 1302
+ L + Q + + K+ +L E EI +++ ++ ++ +Q + + +R
Sbjct: 9021 DQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQR 9080
Query: 1301 KNQTLQDESQRNAKELWNAKARLNN-----VMSKNINLESQNRSLKAELHLQAQK----- 1152
N ++E+++ + L + +S +E +N LQ K
Sbjct: 9081 LNDQTREENKKEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDELEK 9140
Query: 1151 -AFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIE 975
A++ +ER+ VE L S+++ ++ + + +D + + L E+ + + E +
Sbjct: 9141 IAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQDKQNH-LEEKELSIQRKEEEIKIGNT 9199
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGN 795
+ +E L +L+ E K +++ D E ++ + I L N
Sbjct: 9200 EFQIEQEHLNNVLE-------ETNKRQHDLEVMRADIELNKQKNNKDFELLEKIRSELEN 9252
Query: 794 GRANQREFQNKEEDSSGVDL--LKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEE 621
+ + + + +++ V L L+ + RLE +L K E E + + ++ +++
Sbjct: 9253 EKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQTEKEKADLNRVNAEIQR 9312
Query: 620 MQQTL 606
+Q +
Sbjct: 9313 EKQVI 9317
Score = 68.6 bits (166), Expect = 1e-08
Identities = 116/606 (19%), Positives = 255/606 (42%), Gaps = 39/606 (6%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQK-NEDICLK----------IEANNNLLEQKDNII 2157
+ + +L +E ++ ++ E N RQ+ E+I LK I+ L II
Sbjct: 6992 ENIQKLMKELQEERLKTSEALNKERQQFTEEIKLKNDSLDEIQAEIDRQKRALVTDKEII 7051
Query: 2156 VELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAV 1977
+ LQ+ ++ R Q+D + + + Q ERE L++ V + L+ +
Sbjct: 7052 TKQMMDLQKTQDVRR--QSDESDIARANL--QRERESLDQLSVEILKQKQDLERERDELL 7107
Query: 1976 DDRAFMEKQLQDLENQKETVSKELALSVSREQ---KLASDLKALSEKE---ESTKNQLLI 1815
+ +E Q D EN K+ ++ L S E+ +L D + E + +L +
Sbjct: 7108 EQWRLVETQKMDNENVKQLKTELLDEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNL 7167
Query: 1814 QTEQNKQLELEIEKLYGSLQMK------QMENTLLK-----DGNEKIYDLCKLLATKSRE 1668
Q + + ++E++ G LQMK +M+ L + + + Y + L + E
Sbjct: 7168 QKQGIQDERAQLERMKGELQMKADDIERKMQEILYEKQKYAERKSENYKIQTYLDEANAE 7227
Query: 1667 VQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKV---SGILEMLLPMKDDV 1497
VQ + + + D N+E E+ ++ + ++V GAK+ I + L +D +
Sbjct: 7228 VQKLNKELERYDENLE---KCKLELDKARAETERVKQ--GAKIPETQQIEQSLQKERDYI 7282
Query: 1496 FSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHIL 1317
++ + ++ D +++ +++ ++++ + E ++ + + E IQ
Sbjct: 7283 EDIRRNLFKKEEAIEKDKAEIRLRHQELDLIQAKVVKQKEEMVKQKIESERE---IQQEK 7339
Query: 1316 IELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQ 1137
+L+R + L+D+ Q+ +E+ K + K +++++ R + A+K +++
Sbjct: 7340 KKLQRSEEELEDKMQKIKREMIELKLLQDETDGKRKDVDNKMRQV-------ARKRDELE 7392
Query: 1136 EERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAE 957
+ + VES L + L +E E + ++ R E + H E + D+
Sbjct: 7393 KMKADVESASKKLEVDRVMLNTERDELERIKTESQRATE-HMQSHAEERAGDLGEKEPVN 7451
Query: 956 EKLMRILDEL--------ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSL 801
++ R++ E +++ E E ER+++S + + M + I +
Sbjct: 7452 TRIQRLIQEAEKASKMAWSTKHEPEMRMQREVSVEEESVERQDMS-ANMQRMILEIEHAR 7510
Query: 800 GNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEE 621
R + E Q ++ S ++ +K LEF K + +E ++ E Q+ ++E
Sbjct: 7511 ETLRGMKDEVQAARKERSELENMK-----LEFLTMK-KNMEKTYEQQNDEIQKEKQQIES 7564
Query: 620 MQQTLS 603
+ LS
Sbjct: 7565 SKMLLS 7570
Score = 65.5 bits (158), Expect = 1e-07
Identities = 110/608 (18%), Positives = 255/608 (41%), Gaps = 40/608 (6%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIE--LQENFNALRQKNEDICLKIEANNNLLEQKDNI-----IVELSH 2142
E+ +L + E++ I+ + N +E + K E ++ ++K + + +
Sbjct: 14185 ELLQLKQTEQEREIQRGTDDTSNERENYDEKVTYKTELEDSKEKKKPDRDSSLKLTDADS 14244
Query: 2141 KLQENEEQRSALQNDMQSVEQMHAVSQTEREEL-----NRQLVLL-----RDDVNHLKEA 1992
+ E + L+ +Q V Q+ + ++EEL N+ ++L + D+ LKE
Sbjct: 14245 AKTDGEREAQTLETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEE 14304
Query: 1991 LSMAVDDRAFMEKQLQDLENQKETVSKELALSVSRE----QKLASDLKALSEKEESTKNQ 1824
A ++++ + + L+ N E V E+ LS+++E ++ ++++ + K +
Sbjct: 14305 CRSAEEEKSVIMESLERRRNSLEKVQSEV-LSLTQEIDHLAQIKTEMQQIEIKMQIQTRS 14363
Query: 1823 LLIQTEQNKQLEL--EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQE 1650
+ Q E + Q++ E + G + K E K + + KL T + EVQ ++
Sbjct: 14364 VATQWETDVQIQQGQEATETTGHITKKSEEEISAKKTKQPT--VTKLEDTLTSEVQEMRD 14421
Query: 1649 GILKQDINIEDELARTKEVGRSATD-MKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVL 1473
+ K+ +++AR K + + D +++ SD ++ + ++ +E++L
Sbjct: 14422 SLNKE----MEDVARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLL 14477
Query: 1472 G---NINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKR 1302
+ L N +E +T + A+ E ++ ++ + + I++ L++LK+
Sbjct: 14478 QLTHDKEDLSNTLDKKNKEIENNTETSLKKIAQLETT---IVLMKKDKENIENELLQLKQ 14534
Query: 1301 KNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNV 1122
Q + E QR + N + + + ++ LE K + + K +
Sbjct: 14535 TEQ--EREIQRGTDDTSNEREKYDEKVTYKTELEDNKEKKKPDRD-SSLKLTDADSAKTD 14591
Query: 1121 VESEHNVLSSEVENL----KSELKESKDLEGYFLRLFEILLGQHVEVASLDI----ESCR 966
E E L ++V+++ ++ ++L +I+L + A D+ E CR
Sbjct: 14592 GEREAQTLETKVQDVLQLTDDTTQDQEELHDEMENKMKIIL--ELNEAKKDLQKLKEKCR 14649
Query: 965 FAEEKLMRILDELICLRNENAKLKNEAL---YEYHDYERKNVSGSRAEAMSVLISKSLGN 795
AEE+ I++ L RN K+++E L E + + E ++S+
Sbjct: 14650 SAEEEKSVIMESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIETKMQRQTRSVAT 14709
Query: 794 GRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEK--AEMFETKSREAQQMANKLEE 621
+ Q + ++++ K + E +K + ++ +T + E Q+M + L +
Sbjct: 14710 QWETDVQIQQEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNK 14769
Query: 620 MQQTLSDM 597
+ + M
Sbjct: 14770 EMEDVERM 14777
Score = 63.2 bits (152), Expect = 5e-07
Identities = 127/614 (20%), Positives = 263/614 (42%), Gaps = 70/614 (11%)
Frame = -1
Query: 2231 RQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTER 2052
R + ++ I+ LE II++ H+L + +E A++ND + E+M + + E+
Sbjct: 1518 RASDLELSASIQKERQELEHYKEIILKEKHELNKIKEDVKAVKNDAE--ERMIKLHEEEK 1575
Query: 2051 EELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLA 1872
E +++ L E+QLQ +KE K L + Q+L
Sbjct: 1576 EMKTKRVSLQN-------------------WERQLQ---TEKEKNQKGLDAIWNENQQLN 1613
Query: 1871 SDLKALSEKEESTKNQLLIQTEQNK---QLELEIEKLYGSLQMKQMENTLLKDGNEKIYD 1701
+ L KE L +Q+E++K + LEI+++ +Q + ME+ D I +
Sbjct: 1614 ERKQQLDIKE------LHLQSEKSKLEYKKPLEIKQVDAQVQTELMEDASEYDMALSIEE 1667
Query: 1700 LCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEM 1521
L K + + ++ ++ +L Q +E ++A E+ R +++ + + +E+
Sbjct: 1668 LDK----QRQFLEYFKQELLAQKCTMERQMAEI-ELSRDELSLREATLQTATQTTADMEL 1722
Query: 1520 LLPM--------KDDVFSLKEEV-------LGNINSLRNDAQMVQVALEQMQDTKSELFA 1386
L + KD++ K EV I R +MV++ LE+ +D + +
Sbjct: 1723 QLELQKQELEQTKDEMERTKLEVQKGWVDLQTQIAESREKEEMVRIELEKARDVLNRIRQ 1782
Query: 1385 EAEIRAQEV-----LRLQAE---VDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLN 1230
+ E Q + L E ++A + ++ + KR + ++ E QR + + +K +
Sbjct: 1783 DVETEKQTMEADLKFTLAKEFENLEAQRKMMEDEKRALENMKYELQRESGYIERSK---H 1839
Query: 1229 NVMSKNINLESQNRSLK---AELHLQAQKAFQIQEER------------------NVVES 1113
N+ + N+E+ LK EL + Q+Q ER N +++
Sbjct: 1840 NMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERSREIKDLENLRELNELTLNQIKT 1899
Query: 1112 EHNVL----------SSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRF 963
+ +VL E+EN KS++K + Y L+ + L + + DI++ F
Sbjct: 1900 KSDVLEKISELNSQQKDEIENEKSKIK----IREYDLQQMQTDLNRQ-QKEMQDIQNAVF 1954
Query: 962 AEE-KLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRA----------EAMSVL 816
E+ +L + DE+ E K + + ++ E+ N+ RA M+ L
Sbjct: 1955 MEKSELKKSQDEIA----EQLKQVGD-MMQFTQNEKDNLDRERAAIIEQKLQMERDMTHL 2009
Query: 815 ISKSLGNGRANQREFQNKEE--DSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQ 642
+++ L + + ++E N++ + + L+++ + ++ EK EM + + + +
Sbjct: 2010 LNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEM-QLQRQSIAE 2068
Query: 641 MANKLEEMQQTLSD 600
+KLE + QTL++
Sbjct: 2069 EKDKLESVLQTLAE 2082
Score = 63.2 bits (152), Expect = 5e-07
Identities = 119/611 (19%), Positives = 253/611 (41%), Gaps = 43/611 (7%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQ---- 2133
E+ +L + E++ E+Q + + E K+ L + K+ I + L+
Sbjct: 13844 ELLQLKQIEQER--EIQRKADVTSTEKEMYTEKVTYKTELEDSKEKIKPDRDSTLELTDT 13901
Query: 2132 -----ENEEQRSALQNDMQSVEQMHAVSQTEREEL-----NRQLVLL-----RDDVNHLK 1998
+ E + L+ +Q V Q+ + ++EEL N+ ++L + D+ LK
Sbjct: 13902 DSAKTDGEREAQTLETKVQDVLQLTDDTTQDQEELHDEMENKMKIILELNKAKKDLQKLK 13961
Query: 1997 EALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSRE----QKLASDLKALSEKEESTK 1830
E A ++++ + + L+ N E V E+ LS+++E ++ ++++ + K +
Sbjct: 13962 EECRSAEEEKSVIMESLERRRNSLEKVQSEV-LSLTQEIDHLAQIKTEMQQIEIKMQIQT 14020
Query: 1829 NQLLIQTEQNKQLELEIEK---LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQG 1659
+ Q E + Q++ E ++ G + K E K + I + KL T + EVQ
Sbjct: 14021 RSVATQWETDVQIQQEGQEPIETTGHITKKSEEEISAKKTKQPI--VTKLEDTLTSEVQE 14078
Query: 1658 QQEGILKQDINIEDELARTKEVGRSATD-MKKVNSDAGAKVSGI---LEMLLPMKDDVFS 1491
+ D+ IED +AR K + + D +++ SD ++ +E L K
Sbjct: 14079 MR------DMEIED-VARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEETLKEKSRNEE 14131
Query: 1490 LKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIE 1311
++L + + L N +E + T A+ E + ++ + + I++ L++
Sbjct: 14132 TLLQLLHDKDDLSNTLDEKSKEIENITVTFKRNIAQLETT---IAMMKKDKENIENELLQ 14188
Query: 1310 LKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEE 1131
LK+ Q + E QR + N + + ++ LE K + + K
Sbjct: 14189 LKQTEQ--EREIQRGTDDTSNERENYDEKVTYKTELEDSKEKKKPDRD-SSLKLTDADSA 14245
Query: 1130 RNVVESEHNVLSSEVENLKS----ELKESKDLEGYFLRLFEILLGQHVEVASLDI----E 975
+ E E L ++V+++ ++ ++L +I+L + A D+ E
Sbjct: 14246 KTDGEREAQTLETKVQDVLQLTDYTTQDQEELHDEMENKMKIIL--ELNEAKKDLQKLKE 14303
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEAL---YEYHDYERKNVSGSRAEAMSVLISKS 804
CR AEE+ I++ L RN K+++E L E + + E + ++S
Sbjct: 14304 ECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRS 14363
Query: 803 LGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEK--AEMFETKSREAQQMANK 630
+ + Q +E + + K + E +K + ++ +T + E Q+M +
Sbjct: 14364 VATQWETDVQIQQGQEATETTGHITKK-SEEEISAKKTKQPTVTKLEDTLTSEVQEMRDS 14422
Query: 629 LEEMQQTLSDM 597
L + + ++ M
Sbjct: 14423 LNKEMEDVARM 14433
Score = 62.0 bits (149), Expect = 1e-06
Identities = 117/589 (19%), Positives = 235/589 (39%), Gaps = 54/589 (9%)
Frame = -1
Query: 2108 LQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQ 1929
L++ + + V TER EL + L+ + +++ ++ +EK DLE Q
Sbjct: 12202 LESGKDETDGLTEVHTTERRELEITKLALQSEQQEIEKIRQDIDREKNDLEKYRSDLEKQ 12261
Query: 1928 -------KETVSKELALSVSREQKLASDLKALSEKEESTKNQL--------LIQTEQNK- 1797
K+ + E A + + + K+ E+ ES + QL I E NK
Sbjct: 12262 YEEMEICKQNIENERAELEIDLENIIIETKSKQERLESIEVQLQEKNVQMGTILDELNKR 12321
Query: 1796 QLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCK---LLATKSREVQGQQEGILK---Q 1635
Q EL+ K + +QM +T + +E I L K ++ E+Q Q+E + K Q
Sbjct: 12322 QEELDAIKAKTQREKEQMGHTEELEKDELIAILQKREEIVKRHMEEIQNQREELQKEKDQ 12381
Query: 1634 DINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSL---------KE 1482
N++ EL + G+ +M ++ ++ + + L + + F L E
Sbjct: 12382 FGNMQAELQK----GQLEMEMHQLMLNSERDELNGMRVNLEKQKEEFELMQQNLESRRPE 12437
Query: 1481 EVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQ---HILIE 1311
+L +I + + + L + Q+ + +E R +++ +++ E+ Q L E
Sbjct: 12438 SLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKIKQIEGEIKTKQIEMACLEE 12497
Query: 1310 LKRKNQTLQ--------DESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQ 1155
LK+K Q E Q +EL K ++ + L Q K EL
Sbjct: 12498 LKQKELDEQKNMRECENQELQMRREELAKMKTEIDIERDEIQKLRKQYEKEKCELEQIKP 12557
Query: 1154 KAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIE 975
+ + E+ E +H+ + +++LK E +E +E D++
Sbjct: 12558 DLQKREPEKIDAEVQHDEIHGGIDSLKEEREE-------------------IEKMKADLQ 12598
Query: 974 SCRFAEEKLMRILD-ELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVL-ISKSL 801
+ E + I+ E L + A+++ A+ + KN+ + ++L ++K
Sbjct: 12599 NKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIEAILKVTKKQ 12658
Query: 800 GN--GRANQREFQNKEEDSSGVDLLKNKCTRL--------EFQVQKLSEKAEMFETKSRE 651
N + N+ + K E + +L+ + T L EF + K+ E+ +T R
Sbjct: 12659 KNYLEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKMEEREAERKTIERV 12718
Query: 650 AQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGE 504
+MA + E++++ ++ + E T+ +SE++ E
Sbjct: 12719 MDEMAEEHEKIKKEREELVNMEEEIKKQRRVLEESMNEMTKKKSELQHE 12767
Score = 60.5 bits (145), Expect = 3e-06
Identities = 107/584 (18%), Positives = 246/584 (42%), Gaps = 26/584 (4%)
Frame = -1
Query: 2291 RLYEEEKQHTIELQENFNALRQKNEDI-CLKIE---ANNNLLEQKDN---IIVELSHKLQ 2133
RL EE + Q+ A + + D +K E AN L +Q++ I E+ + +
Sbjct: 6581 RLNEEINIQKVNQQKQATAFQMEKTDFERIKTEIDQANKELADQQEKNKKTITEMQKERE 6640
Query: 2132 ENEEQRSALQNDMQSV-EQMHAVSQTERE--ELNRQLVLLRDDVNHLKEALSMAV----- 1977
EE R+ + ++++ + ++S E E +L ++ + +++ LK + M +
Sbjct: 6641 TLEEMRANISKQVETITNENKSLSSRESELAKLQEDILQQQQEMDELKNTIMMEMCQLDQ 6700
Query: 1976 --DDRAFMEKQLQDLENQKET----VSKELALSVSREQKLASDLKALSEKEESTKNQLLI 1815
D ++K++ DL + +T V +E +++ + + SD+ +L ++E+ + L
Sbjct: 6701 RQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLK 6760
Query: 1814 QTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQ 1635
E+ +E E E L +L + +K E L + ++ +++ + K
Sbjct: 6761 LNEEKDLIEKERELLTKNLDHTDKDKMDMKRELEN-------LKVEKETIKNEKKELEKM 6813
Query: 1634 DINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSL 1455
I+++ + KE D + + + A+ + L++ + F EE L
Sbjct: 6814 KISLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFI--EERLDQTEKK 6871
Query: 1454 RNDAQMVQVALEQ----MQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTL 1287
R + ++ +Q TK E+ + E E+ R + E++ + L ++ N
Sbjct: 6872 RRKTYYTEDLFQEEKTDLQKTKEEINYDRE----EIYRQRTELNKEKETLKQMHTSNLKE 6927
Query: 1286 QDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEH 1107
+ ++ +++ L+ + ++ L+++ R + ++ ++ ++ + +++E
Sbjct: 6928 IENIEKEKEKIQRTWNELDQIRAE---LQNKQRDMDDTTNIMMKEKAELARDLENLQNEK 6984
Query: 1106 NVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL 927
+ L EN++ +KE L+ L+ E L + + E + + L I E+
Sbjct: 6985 DELQKSRENIQKLMKE---LQEERLKTSEALNKERQQFT----EEIKLKNDSLDEIQAEI 7037
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRAN-QREFQNKEEDS 750
R + A + ++ + + + R + S RAN QRE + D
Sbjct: 7038 D--RQKRALVTDKEIITKQMMDLQKTQDVRRQ------SDESDIARANLQRE--RESLDQ 7087
Query: 749 SGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEM 618
V++LK K LE + +L E+ + ET+ + + + E+
Sbjct: 7088 LSVEILKQK-QDLERERDELLEQWRLVETQKMDNENVKQLKTEL 7130
Score = 59.7 bits (143), Expect = 5e-06
Identities = 119/587 (20%), Positives = 244/587 (41%), Gaps = 18/587 (3%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
KE + EE + EL+E Q+N+++ E +LLE++ + +LQ+
Sbjct: 11771 KEYESIIEETNRKRTELEEIEVDQSQQNKNV----ETMKDLLEKERKDTEKEREELQKQA 11826
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQ----LVLLRDDVNHLKEALSMAVDDRAFME 1956
+ + E+M S E ++L Q ++ RDD+ KE + ++ ++
Sbjct: 11827 DDLEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQ 11886
Query: 1955 KQLQDLENQKETVSKELA---LSVSREQK-LASDLKALSEKEESTKNQLLIQTEQNK-QL 1791
K++Q+ +N+ E + EL + + +EQK L L ++E+ + + +++ + K Q
Sbjct: 11887 KEIQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLE---IVRVDYEKHQQ 11943
Query: 1790 ELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDEL 1611
++E ++ ++ +++ + K L+ K E G+LK+++
Sbjct: 11944 QIEEMRVKTKMERDELDQLMAK----------MLMDRKENERSKDMIGLLKKEM------ 11987
Query: 1610 ARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQ 1431
+ K N DA E L K + + K+++ ++ +A V+
Sbjct: 11988 -----------EQTKFNLDAQE------EELKLEKQKIQNEKKDLEMFKAEIKREASEVK 12030
Query: 1430 VALEQM--QDTKS-ELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAK 1260
EQ +DTK+ E E + Q V + E + IQ + E+KR + E + K
Sbjct: 12031 TLKEQQLEKDTKAFEALKEEHLPGQFVQQKGGEFERIQ--IDEVKR----ILSEIHKEKK 12084
Query: 1259 ELWNAKARLNNVMSKNINLESQNRSLKAELHL--QAQKAFQIQEERNVVESEHNVLSSEV 1086
EL K L + + ++S+ S + ++ L A + +++ +V S+ +
Sbjct: 12085 ELERNKQILEHQREALLEIKSKQPSERLDVILVSSATQTSDLEDIPDVSASQGETVEKHT 12144
Query: 1085 ENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMR----ILDELICL 918
+ +K E S E Y + + L Q + E + A+ ++ I D I +
Sbjct: 12145 DIIK-EYTTSIPKEEYEI---DKLKQQGDKKLKSTREDTKMADTEVTTQYKYIPDPSIMM 12200
Query: 917 RNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVD 738
+ E+ K + + L E H ER+ + ++ A Q E Q E+ +D
Sbjct: 12201 KLESGKDETDGLTEVHTTERRELEITKL---------------ALQSEQQEIEKIRQDID 12245
Query: 737 LLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDM 597
KN + ++K E+ E+ + Q + N+ E++ L ++
Sbjct: 12246 REKNDLEKYRSDLEKQYEEMEICK------QNIENERAELEIDLENI 12286
>ref|XP_005159741.1| PREDICTED: titin isoform X4 [Danio rerio]
Length = 15580
Score = 126 bits (317), Expect = 4e-26
Identities = 169/712 (23%), Positives = 304/712 (42%), Gaps = 41/712 (5%)
Frame = -1
Query: 2258 ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQ 2079
+LQ +L + E + L EA N E I +L K +E E+ + Q+D Q VE+
Sbjct: 5123 DLQHKMFSLDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVEE 5182
Query: 2078 MHAVSQTER-------EELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLE----- 1935
M A Q ER EE NR+ ++L + +KE + DR +EK+ DLE
Sbjct: 5183 MTAQIQKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSK 5242
Query: 1934 --NQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGS 1761
KE + K+ + ++ QK DL+ ++EK + + Q EQ KQ + E+++L
Sbjct: 5243 LLRAKENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTE 5302
Query: 1760 LQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQ---EGILKQDINIEDELARTK-EV 1593
+Q Q E L+ E I L + E+ QQ I++ N +L + K E
Sbjct: 5303 IQNLQQE---LEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEET 5359
Query: 1592 GRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINS--------LRNDAQM 1437
+M+K D + E L MK L+++VL + S L +A
Sbjct: 5360 EEQKQEMEKEKHDFDQSRKSLDEDLKMMK-----LQKQVLEDEKSKLEQMKIELEREAVE 5414
Query: 1436 VQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQ-TLQD--ESQRN 1266
++ E++Q+ + L E +E L E +L E+K N+ TL D + N
Sbjct: 5415 IRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKSN 5474
Query: 1265 AKEL-WNAKARLNNVMSKNINL---ESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVL 1098
+E+ N + +V +K NL E + R L+AE+H Q + +I++E+ +ESE +
Sbjct: 5475 LEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQR---EIEKEKINIESERAAI 5531
Query: 1097 SSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICL 918
+VE+L+ ++ I L + E LD E+ +E L ++ EL
Sbjct: 5532 IKDVEDLQHKI---------------ICLDRDAESLKLDREAFENEKEVLKQMKTELERE 5576
Query: 917 RNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVD 738
+E K+K E HD + R E M+ I K ++ E N E+++ D
Sbjct: 5577 ADEIEKIKLET---QHDRQ-------RVEEMAAQIQK-------DRDEINNLIEETNRKD 5619
Query: 737 LLKNKCTR-LEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXI 561
++ N+ R +E +++ + +M E + + ++ ++L ++++ L
Sbjct: 5620 MVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQ---------KEN 5670
Query: 560 RVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPL------IQXXXXX 399
+ ++KE L + KH+E ++ + D+ T + ++
Sbjct: 5671 TLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEI 5730
Query: 398 XXXXXXKIDTRTSETQEIDTLMDDNRKYW-NRVSHFTKQTQSLQNSVQELQQ 246
++D R SE + T M+D + N K + ++ QE+++
Sbjct: 5731 IMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEK 5782
Score = 101 bits (251), Expect = 2e-18
Identities = 162/831 (19%), Positives = 370/831 (44%), Gaps = 70/831 (8%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLK--IEANNNLLEQKDNIIVELSHKLQE 2130
+E++ +++ +Q E + +QK +D+ + ++ + LE+ ++E+ K +
Sbjct: 10782 EEINHKWKQLQQRIDEFDAQVS--KQKEQDLPKEKGMKEDRKSLEETKANVIEMKTKAEP 10839
Query: 2129 NE---EQRSALQNDMQSVEQMHAVSQTEREELNR---QLVLLRDDVNHLKEALSMAVDDR 1968
E E+ + + + E++ + +TER+EL + +L +R +++H ++ L+ D
Sbjct: 10840 EEIKKEKEKENEEEEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQKKLN---DYM 10896
Query: 1967 AFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALS------EKEESTKNQLLIQTE 1806
+E++ +DLE K + K+ +L + ++ + EK + +L+++ E
Sbjct: 10897 KMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVEVE 10956
Query: 1805 -QNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDI 1629
Q K ++L+ E+L Q E LL K+ + + + E++ ++E + + +I
Sbjct: 10957 EQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKKVDEEIKKERETLREMEI 11016
Query: 1628 NIEDELARTK----EVGRSATDMKKVNSDAGAKVSGILEMLLPMK---DDVFSLKEEVLG 1470
+++ E + E R D++K+++D I E L +K D + +EE+
Sbjct: 11017 HLKKEKEELRSIIEETQRRKEDLEKMSTD-------INEQKLHLKNQRDLLEQEREEINH 11069
Query: 1469 NINSLRN-----DAQM-----------VQVALEQMQDTKSELF-AEAEIRAQEVLRLQAE 1341
+ L+ DAQ+ ++ + +++TK+ + + + QE+++ + E
Sbjct: 11070 EMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEE 11129
Query: 1340 VDAIQ-HILIELKRKN-QTLQDESQRNAKELWNAKARLNNVMSKNINLESQN-RSLKAEL 1170
D + +++E++R+ ++ E +R E+ + + +LN+ K I E ++ +K+E+
Sbjct: 11130 EDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLND-DKKIIEQEKEDLEKMKSEI 11188
Query: 1169 HLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDL-EGYFLRLFEILLGQHVEV 993
Q Q Q++EER+ E ++ + +++E + +++ SK++ + +++ E ++
Sbjct: 11189 MTQRQ---QMEEERS--ELDNKIKQTDLE--RHDIENSKEIVQKLMVKVEEQRKDIRLQK 11241
Query: 992 ASLDIESCRFAEEKLMRILDELICLRNENAKLK---------NEALYEYHDYERKNVSGS 840
LDIE + A+E+ + ++ L+NEN ++K E L E + RK
Sbjct: 11242 EELDIERQKIADEQGL-VVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEM 11300
Query: 839 RA-------------EAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQV 699
R+ E MS ++K NQR+ +E + + +K T+L+ ++
Sbjct: 11301 RSVIEETQRRKKEDLEKMSTDVNKQ-NQDLMNQRDLLKQEREE-----INHKWTQLQQRI 11354
Query: 698 Q----KLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENT 531
++S++ E TK ++ ++ LEE + + +M + + ++E
Sbjct: 11355 DEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKE-EEEVM 11413
Query: 530 RLRSEM-KGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSET 354
R + EM K EL +S R S I DD +I+ +I + +
Sbjct: 11414 RAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQM 11473
Query: 353 QEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSI 174
+E + +D N++ + ++NS + +Q+ M +
Sbjct: 11474 EEERSELD------NKIKQTDLERHDIENSKEIVQKL-------------------MVEV 11508
Query: 173 EKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEEV 21
E+Q K++ + +L ++ + G N N E+ ++DEE+
Sbjct: 11509 EEQRKDIRLQKEELDIERQKIADEQ--GLVVQNKAKLQNENERIKEMDEEI 11557
Score = 100 bits (249), Expect = 3e-18
Identities = 155/794 (19%), Positives = 326/794 (41%), Gaps = 68/794 (8%)
Frame = -1
Query: 2282 EEEKQHTIELQENFN-ALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQ---- 2118
EE+KQ + ++N + +++ +ED+ + ++ ++E++ N + ++ +LQ ++
Sbjct: 4234 EEQKQEMEKERDNMDQSIKSLDEDLKM-MKLQKQVIEEEKNKLEQMKFELQREADEIRKI 4292
Query: 2117 RSALQNDMQSVEQM------------HAVSQTEREE--LNRQLVLLRDDVNHLKEALSMA 1980
+ QN+ QS+E+M H T+RE+ L+ V + + L+ +
Sbjct: 4293 KEETQNERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRIL 4352
Query: 1979 VDDRAFMEKQLQDLENQKETVS------KELALSVSREQKLASDLKALSEKEEST----- 1833
+ R + KQ +D+EN+KE K+L V ++Q K E E +
Sbjct: 4353 EEMRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREK 4412
Query: 1832 KNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATK-------- 1677
+N + ++++ +E++++++ ++ + ++ LLK E + KL++ +
Sbjct: 4413 QNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQ--KLMSIERDSESLKL 4470
Query: 1676 SREVQGQQEGILKQ---DINIE-DELARTK---EVGRSATDMKKVNSDAGAKVSGILEML 1518
RE G ++ +LKQ D+ I+ DE+ + K + R + K L +
Sbjct: 4471 DREAFGNEKEVLKQMKTDLQIQADEIEKIKLETQHDRQRVEEKTAQIQKDRDEINNLIVE 4530
Query: 1517 LPMKDDVFS-LKEEVLGNINSLRNDAQMVQVALEQMQDTKSELF-------AEAEIRAQE 1362
KD V + + ++ I S+++D M++ ++ T+SEL + EI ++
Sbjct: 4531 TNRKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLEKTRSELARAKENLETQREIERKD 4590
Query: 1361 VLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSL 1182
+ +++ + H + + + + QDE + E+ N + L + SQ
Sbjct: 4591 IEKMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDLR 4650
Query: 1181 KAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-KESKDLEGYFLRLFEILLGQ 1005
++EL Q I E + + E E K E+ KE D + L E L
Sbjct: 4651 QSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLKMM 4710
Query: 1004 HVEVASLDIESCRFAEEK--LMRILDELICLRNE--NAKLKNEALYEYHDYERKNVSGSR 837
++ ++ E + + K L R DE+ ++ E N + E + E ER+++S
Sbjct: 4711 KLQKQVIEEEKSKLKQMKIELEREADEIRKVKEETQNERQIFEKMTEALKKEREDLSEDA 4770
Query: 836 AEAMSVLISKSLGN---------GRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSE 684
VL + N R+N +E +E S + ++NK ++ + +KL +
Sbjct: 4771 KRKNQVLDEMKVANESTLADILRERSNLQEM--RENISKQTEDVENKKEKIRLREEKLKQ 4828
Query: 683 -KAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKG 507
+AE+ + +S ++ +N E + D+ SLK + +E K
Sbjct: 4829 LQAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENE-KE 4887
Query: 506 ELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDD 327
EL ++ RE I++I + + + ++ T + M++
Sbjct: 4888 ELKQMKTELEREADEIEKIKLETQHERQRVE-----------------EMTADFMETMNN 4930
Query: 326 NRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNI 147
RK N K + +Q QE+++ S++K LK + +
Sbjct: 4931 ERKQLN------KNKEEMQEQKQEMEKERHDMDQ------------SRKSLDKNLKMMKL 4972
Query: 146 HVMQLVEHNTRLKK 105
+ E +L++
Sbjct: 4973 QKQVIEEEKNKLEQ 4986
Score = 97.1 bits (240), Expect = 3e-17
Identities = 121/592 (20%), Positives = 267/592 (45%), Gaps = 29/592 (4%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQ----KDNIIVELSHKLQ 2133
E+ ++ EE + L++ AL+++ ED+ + + NN +L++ ++ + ++ +
Sbjct: 5414 EIRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKS 5473
Query: 2132 ENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK 1953
EE R + + VE + +EL + + +++ +RA + K
Sbjct: 5474 NLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIK 5533
Query: 1952 QLQDLENQKETVSKEL-ALSVSR-----EQKLASDLKALSEKEESTKNQLLIQTEQNKQL 1791
++DL+++ + ++ +L + R E+++ +K E+E ++ ++T+ ++Q
Sbjct: 5534 DVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIKLETQHDRQ- 5592
Query: 1790 ELEIEKLYGSLQMKQME-NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDE 1614
+E++ +Q + E N L+++ N K D+ +L K+R+++ + + I +D
Sbjct: 5593 --RVEEMAAQIQKDRDEINNLIEETNRK--DM--VLNEKNRDIEEKIKSIQSD----KDM 5642
Query: 1613 LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
L + K D++K S+ L +K+D+ KE L I R D
Sbjct: 5643 LEKEKH------DLEKTRSE-----------LYKVKEDLEKQKENTLAEIQKERED---- 5681
Query: 1433 QVALEQMQDTKSELFAEAEIRAQEVLRLQAEVD----AIQHILIEL-KRKNQTLQDESQR 1269
LE+M + + E + + +++ + Q E+D IQ++ EL K K ++D SQ
Sbjct: 5682 ---LEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQL 5738
Query: 1268 NAK--ELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLS 1095
+ + EL + +N++M N Q K E+ Q Q ++++ER+ ++ L
Sbjct: 5739 DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQ---EMEKERDNMDQSRKSLD 5795
Query: 1094 SEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLR 915
+ + +K + K+ + E L +I L + + S E + ++L ++ +ELI +
Sbjct: 5796 EDQKKMKLQ-KQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREK 5854
Query: 914 NENAKLKNEALYEYHDYERKNVSGSRAEA---MSVLISKSLGNGRANQREFQNKEEDSSG 744
A L + E + V+ + A I + + + +E+ + E++ S
Sbjct: 5855 ESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENISKLKEYIDNEKEKS- 5913
Query: 743 VDLLKNKCTRLEFQVQKLSEKAEMFETK--------SREAQQMANKLEEMQQ 612
L +++ +L+ +VQK K +M +T RE Q M +L++ +
Sbjct: 5914 -KLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKKSE 5964
Score = 96.7 bits (239), Expect = 4e-17
Identities = 117/620 (18%), Positives = 263/620 (42%), Gaps = 66/620 (10%)
Frame = -1
Query: 2282 EEEKQHTI-ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
E++K++T+ E+Q+ L + NE+I +++ + EQ + K E ++ ++ +
Sbjct: 4125 EKQKENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQ-------MKQKQDELDQLKTEI 4177
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
QN Q +E+ + +R EL+ + L ++ + + ++R ++K +++E QK
Sbjct: 4178 QNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQK 4237
Query: 1925 ETVSKELALSVSREQKLASDLKAL--------SEKEESTKNQLLIQTEQNKQLELEIEKL 1770
+ + KE + L DLK + EK + + + +Q E ++ +++ E
Sbjct: 4238 QEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQ 4297
Query: 1769 YGSLQMKQMENTLLKDGNEKIY------------DLCKL--------LATKSREVQGQQE 1650
+++M L+K+ + ++ D ++ L + R ++ +E
Sbjct: 4298 NERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRILEEMRE 4357
Query: 1649 GILKQDINIEDELARTK-------------EVGRSATDMKKVNSDAGAKV-----SGILE 1524
I KQ +IE+E ++K + +S DM+K N ++ V ++
Sbjct: 4358 NISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQNMMT 4417
Query: 1523 MLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFA-------------- 1386
L +DV +E+L L ND+ +++ + M+D K +L +
Sbjct: 4418 ELKKKSEDVEIQMKEILTEKELLENDSNLLK---KDMEDLKQKLMSIERDSESLKLDREA 4474
Query: 1385 ---EAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSK 1215
E E+ Q LQ + D I+ I +E + Q +++++ + K+ + K
Sbjct: 4475 FGNEKEVLKQMKTDLQIQADEIEKIKLETQHDRQRVEEKTAQIQKDRDEINNLIVETNRK 4534
Query: 1214 NINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELK-ESKDLEGY 1038
++ L +R ++ ++ +++ER+ +E + L+ ENL+++ + E KD+E
Sbjct: 4535 DMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLEKTRSELARAKENLETQREIERKDIE-- 4592
Query: 1037 FLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYER 858
+ + S ++ + EE++ + DEL L+ E L+ E
Sbjct: 4593 ----------KMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQNLQQE---------- 4632
Query: 857 KNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGV-DLLKNKCTRLEFQVQKLSEK 681
E +I K+ Q E ++ + + + + +KN+ +L+ ++ E+
Sbjct: 4633 -------LEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQ 4685
Query: 680 AEMFETKSREAQQMANKLEE 621
+ E + + Q L+E
Sbjct: 4686 KQEMEKEKHDFDQSRKSLDE 4705
Score = 96.7 bits (239), Expect = 4e-17
Identities = 128/572 (22%), Positives = 261/572 (45%), Gaps = 11/572 (1%)
Frame = -1
Query: 2282 EEEKQHTIELQEN-FNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
+E+ HT EL+++ A+ QK E+I + +E+ N EL + + ++ L
Sbjct: 12782 KEQMGHTEELEKDELIAILQKREEIVKRH------MEEIQNQREELQKEKDQFGNMQAEL 12835
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
Q +E + +ER+ELN V L E + ++ R E L+D+ +K
Sbjct: 12836 QKGQLEMEMHQLMLNSERDELNGMRVNLEKQKEEF-ELMQQNLESRR-PESLLEDILKEK 12893
Query: 1925 ETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQ 1746
+ V +E+A +S+EQ E +N I +E K++E +I+++ G ++ KQ
Sbjct: 12894 KRV-EEMAAQLSKEQ-------------EEFRN---IMSETIKRME-KIKQIEGEIKTKQ 12935
Query: 1745 MENTLLKDGNEKIYDLCK-LLATKSREVQGQQEGI--LKQDINIE-DELAR-TKEVGRSA 1581
+E L++ +K D K + +++E+Q ++E + +K +I+IE DE+ + K+ +
Sbjct: 12936 IEMACLEELKQKELDEQKNMRECENQELQMRREELAKMKTEIDIERDEIQKLRKQYEKEK 12995
Query: 1580 TDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTK 1401
+++++ D L+ P K D +E+ G I+SL+ + + ++ +Q+
Sbjct: 12996 CELEQIKPD--------LQKREPEKIDAEVQHDEIHGGIDSLKEEREEIEKMKADLQNKL 13047
Query: 1400 SELFAEAEIRAQEVLRLQAEVDAIQHILIELK--RKNQTLQDESQRNAKELWNAKARLNN 1227
E +I +E L+ + I+ + +E + ++ LQDE + L K + N
Sbjct: 13048 REAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIEAILKVTKKQKNY 13107
Query: 1226 VMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDL 1047
+ N NL + L+ + ++ ++ ++ E H S++E ++E K +
Sbjct: 13108 LEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEFH---MSKMEEREAERKTIE-- 13162
Query: 1046 EGYFLRLFEILLGQHVEVASLDIESCRFAEE--KLMRILDELICLRNENAKLKNEALYEY 873
R+ + + +H ++ E EE K R+L+E + NE K K+E +E
Sbjct: 13163 -----RVMDEMAEEHEKIKKEREELVNMEEEIKKQRRVLEESM---NEMTKKKSELQHER 13214
Query: 872 HD-YERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQ 696
+ Y++K + + +I+ +R Q+KE++ +LK + +
Sbjct: 13215 SELYKQK-------QQLEDMIASESKRDVDTERSRQDKEDE----QILKREREEIADMKD 13263
Query: 695 KLSEKAEMFETKSREAQQMANKLEEMQQTLSD 600
+L ++ E ET + +E+MQ L+D
Sbjct: 13264 QLLKEKEDVETTKERINREKEHIEKMQSQLND 13295
Score = 95.9 bits (237), Expect = 7e-17
Identities = 121/615 (19%), Positives = 259/615 (42%), Gaps = 8/615 (1%)
Frame = -1
Query: 2291 RLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRS 2112
R+ E + Q + + +E+ ++ ED E N+LE K E K +E EE+
Sbjct: 11908 RIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQ 11967
Query: 2111 ALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLEN 1932
++ ++ + + E E++ QL +R +++H ++ L+ DD+ +E++ +DLE
Sbjct: 11968 EMRVKVE-------MERKEIEQIKSQLERVRSEMDHEQKKLN---DDKKMIEQEKEDLEK 12017
Query: 1931 QKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQM 1752
K + K+ +L +K ++ +N E ++L +E+EK +Q
Sbjct: 12018 MKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENS----KEIVEKLMVEVEKQKHEIQF 12073
Query: 1751 KQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDM 1572
++ E L +KI D LL E Q + E I + D I+ E KE+ +
Sbjct: 12074 QKEE---LDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNLQKE 12130
Query: 1571 KKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSEL 1392
K+ + E L M D+ K++++ + L+ + + + L Q+Q E
Sbjct: 12131 KEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEF 12190
Query: 1391 FAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKN 1212
+ I + + E+D L + ++ +++ +E+ R EL +
Sbjct: 12191 ETTSNILVTTKMEEKTEMD---EKLQQAIKEYESIIEETNRKRTELEEIE---------- 12237
Query: 1211 INLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFL 1032
++ QN++++ L +++ER E E L + ++L+ ++ E D E
Sbjct: 12238 VDQSQQNKNVETMKDL-------LEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSK 12290
Query: 1031 RLFEI---LLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYE 861
R + LL Q + +E +M+ +EL L+ E KNE + E
Sbjct: 12291 RSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKEIQNQKNEMEEIKCELE 12350
Query: 860 RKNVSGSRAEAMSVLISKSLGNGRANQREFQ----NKEEDSSGVDLLKNKCTRLEFQVQK 693
K + + + + +SL ++ + + E+ ++ ++ K ++ +
Sbjct: 12351 TKRIEIIKEQKR---LEESLNTVNEERQYLEIVRVDYEKHQQQIEEMRVKTKMERDELDQ 12407
Query: 692 LSEKAEMFETKSREAQQMANKLE-EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSE 516
L K M ++ ++ M L+ EM+QT ++ ++++ KK+ ++E
Sbjct: 12408 LMAKMLMDRKENERSKDMIGLLKKEMEQTKFNLDAQEEELKLEKQKIQNEKKDLEMFKAE 12467
Query: 515 MKGELTPSRSFKHRE 471
+K E + ++ K ++
Sbjct: 12468 IKREASEVKTLKEQQ 12482
Score = 94.7 bits (234), Expect = 2e-16
Identities = 148/745 (19%), Positives = 307/745 (41%), Gaps = 60/745 (8%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQ------ENFNALRQKNED-----ICLKIEANNN-----LLEQK 2169
E+ R EE ++ + LQ EN A Q+ ED I +KI+ L ++
Sbjct: 9357 EMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQLDKET 9416
Query: 2168 DNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEAL 1989
+ E+ K+++ E + + ++ Q +E + + E++EL ++ L D + L
Sbjct: 9417 KRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREK 9476
Query: 1988 SMAVDDR---AFMEKQLQDLENQKETVSKELALSVS----------REQKLASDLKALSE 1848
++R ++ QL+DL + E V ++L L S ++Q+L + ++
Sbjct: 9477 QETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENK 9536
Query: 1847 KEESTKNQLLIQTEQNKQ-LELEIEKLYGSL-QMKQMENTL--LKDGNEKI--------Y 1704
KE+ + Q +TEQ KQ LE+ K+ +M + L KD EKI +
Sbjct: 9537 KEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDELEKIAYKTNKERH 9596
Query: 1703 DLCKLLATKSREVQG-QQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAK---VS 1536
++ ++ A ++Q +Q+G + QD E + + R ++K N++ + ++
Sbjct: 9597 EVEQMQAELHSQIQAIEQQGQIMQDKQNHLE-EKELSIQRKEEEIKIGNTEFQIEQEHLN 9655
Query: 1535 GILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSEL--FAEAEIRAQE 1362
+LE + D+ ++ ++ N D ++++ ++++ K +L + E + E
Sbjct: 9656 NVLEETNKRQHDLEVMRADIELNKQKNNKDFELLEKIRSELENEKYDLQIWTEQQKHLVE 9715
Query: 1361 V--LRLQAEVDAIQHILIELKRKNQTLQDES---QRNAKELWNAKARLNNVMSKNINLES 1197
V L+ E + ++ + IEL+ K + + E R E+ K ++
Sbjct: 9716 VQLQELEKEKERLEKMEIELQSKREQTEKEKADLNRVNAEIQREKQVIDKKRHMTNRAME 9775
Query: 1196 QNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEI 1017
+ ++K EL + +K IQ E+ +E E ++ E ENL L+E K +
Sbjct: 9776 ELETIKTELKERQEK---IQTEQEKLEEEKLLVQIEAENLNKVLEEIKRQQ--------- 9823
Query: 1016 LLGQHVEVASLDI----ESCRFAEEKLMR---ILDELICLRNENAKLKNEALYEYHDYER 858
+ +E++ D+ E C A E+ R ++E I NENAK + ER
Sbjct: 9824 ---EKLEISEADLKVMKEQCENAREETERKKCDIEEQI-QNNENAK-------HLLEQER 9872
Query: 857 KNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKA 678
K++ + E + + +K LL+ K + Q L ++
Sbjct: 9873 KDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEKEK 9932
Query: 677 EMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELT 498
E K + + N+++ + + ++ + + +E+ R +E KG+L
Sbjct: 9933 EDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGDLE 9992
Query: 497 PSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRK 318
R+ ++ I+E+ + + + + +ID + +++ R
Sbjct: 9993 IMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKERN 10052
Query: 317 YWNRV-SHFTKQTQSLQNSVQELQQ 246
++ S Q Q +++ EL Q
Sbjct: 10053 DLEKMKSELMTQRQQMEDERSELDQ 10077
Score = 94.4 bits (233), Expect = 2e-16
Identities = 129/603 (21%), Positives = 273/603 (45%), Gaps = 37/603 (6%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEE 2121
E+ R +E ++ +E Q + + + I + + NNL+E+ + + L+ K ++ EE
Sbjct: 4032 ELERETDEIEKIKLETQHDRQRVEEMTAQITKERDKINNLIEETNRKDMVLNEKNRDIEE 4091
Query: 2120 QRSALQNDMQSVE-QMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQ 1944
+ ++Q+D +E + H + +T E L +++D+ KE + A ++K+ +
Sbjct: 4092 KIKSIQSDKDMLEKEKHNLEKTRSE-----LYKVKEDLEKQKE------NTLAEIQKERE 4140
Query: 1943 DLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYG 1764
DLE E ++ E+ +E+++ L + + +N +Q E K+ E+ I K
Sbjct: 4141 DLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEIQN---LQQELEKEKEI-IMKDRS 4196
Query: 1763 SLQMKQME----NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKE 1596
L ++Q E T + D E + + KLL E++ Q++ + K+ N++ + E
Sbjct: 4197 ELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQKQEMEKERDNMDQSIKSLDE 4256
Query: 1595 VGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQ 1416
+ K+V + K+ + L D++ +KEE +N+ Q ++ +
Sbjct: 4257 DLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEET-------QNERQSLEKMTKA 4309
Query: 1415 MQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKAR 1236
+ + +L AE +E L A + + +L+R+ + L++ + +K+ +
Sbjct: 4310 LIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRILEEMRENISKQTED---- 4365
Query: 1235 LNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-KE 1059
+ N K+ E + + L+ E+ Q +I E+ +ESE V+ E +N+ +EL K+
Sbjct: 4366 IENEKEKSKLREDELKKLQTEVQKQQS---EIDMEKTNIESERAVMIREKQNMMTELKKK 4422
Query: 1058 SKDLEGYFLRLFEILLGQHV--------------------------EVASLDIESCRFAE 957
S+D+E +++ EIL + + E LD E+ +
Sbjct: 4423 SEDVE---IQMKEILTEKELLENDSNLLKKDMEDLKQKLMSIERDSESLKLDREAFGNEK 4479
Query: 956 EKLMRILDELICLRNENAKLKNEALYEYHDYERK--NVSGSRAEAMSVLISKSLGNGRAN 783
E L ++ +L +E K+K E ++ E K + R E ++++ + + N
Sbjct: 4480 EVLKQMKTDLQIQADEIEKIKLETQHDRQRVEEKTAQIQKDRDEINNLIVETNRKDMVLN 4539
Query: 782 Q--REFQNK-EEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQ 612
+ R+ + K + S D+L+ + LE +L+ E ET+ RE ++ +E+M++
Sbjct: 4540 EMDRDIEEKIKSIQSDKDMLEKERHNLEKTRSELARAKENLETQ-REIER--KDIEKMKK 4596
Query: 611 TLS 603
+S
Sbjct: 4597 NIS 4599
Score = 94.0 bits (232), Expect = 3e-16
Identities = 135/605 (22%), Positives = 286/605 (47%), Gaps = 41/605 (6%)
Frame = -1
Query: 2291 RLYEEEKQHTIELQENF-NALRQKNEDICLKIEANNNLLEQKDNIIVE---LSHKLQENE 2124
R+ E + Q + +E+ N + + E CL+ E N ++E K +E ++ K++E +
Sbjct: 10225 RIDEFDAQVRKQKEEDLTNQKKMEEERKCLE-EVNGKIIEMKTKAELEHHEINQKIEELQ 10283
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNR---QLVLLRDDVNH----LKEALSMAVDDRA 1965
+ + + + E M + ERE+L++ +LV + +V+H L + + M ++
Sbjct: 10284 TLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKE 10343
Query: 1964 FMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLEL 1785
+EK ++ QK+ + KE + ++ Q+ + + + +E + + EQ +++L
Sbjct: 10344 DLEKMKSEIMTQKQEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRHEIQL 10403
Query: 1784 EIEKLYGSLQMKQMENTL-------LKDGNEKIYDLCKLLATKSREVQGQQEGILKQD-- 1632
+ E+L Q E L L++ NE+I ++ +++ K RE + E L+++
Sbjct: 10404 QKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEVI-KKERETLKEMEAHLEKEKE 10462
Query: 1631 --INIEDELARTKE-VGRSATDMKKVNSDAGAKVSGILEM----------LLPMKDDVFS 1491
+I +E R KE + + +TD+K+ N D K +LE L + D F
Sbjct: 10463 EMKSITEETRRQKEDLEKMSTDIKEQNQDL-MKQRDLLEQEKEDINHEWTQLQQRIDEFD 10521
Query: 1490 L-----KEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQ 1326
KEE L ++ + + +LE+ + E+ +AE+ + + + E +
Sbjct: 10522 AQVSKQKEEDLTKQKEMKEERK----SLEETKARIIEMKTKAELEDIKKEKEKEEEEEEM 10577
Query: 1325 HILIELKRKN-QTLQDESQRNAKELWNAKARLNNVMSKNINLESQN-RSLKAELHLQAQK 1152
+ +E+ K ++ E +R E+ + + +LN+ K I E QN +K+E+ Q Q
Sbjct: 10578 RVKVEMDGKELDRIKSELKRERSEIDHEQKKLND-DKKIIEQEKQNLEKMKSEIMKQRQ- 10635
Query: 1151 AFQIQEERNVVESEHNVLSSEVENLKSELKESKDL-EGYFLRLFEILLGQHVEVASLDIE 975
Q++EER+ E E+ + + +E K +++ SK++ + + + E + LDIE
Sbjct: 10636 --QMEEERS--ELENKIKQTYIE--KCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIE 10689
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGN 795
+ A+E+ + I ++ L+NEN +++N L E ER+ + + M + K
Sbjct: 10690 RQKIADEQDLLIQNKSE-LQNENERIRN--LNEIIKKERETL-----KEMEAHLEKKKEE 10741
Query: 794 GRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQ 615
++ E + +ED L+ T + Q + L + ++ E +E +++ +K +++Q
Sbjct: 10742 IKSVSEETRRLKED------LEKMSTDVNKQNKDLMNQRDLLE---QEREEINHKWKQLQ 10792
Query: 614 QTLSD 600
Q + +
Sbjct: 10793 QRIDE 10797
Score = 92.4 bits (228), Expect = 8e-16
Identities = 119/631 (18%), Positives = 280/631 (44%), Gaps = 68/631 (10%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE- 2124
E + + +Q E+++ N L +K EDI + + + + +E+ + E E
Sbjct: 294 ETQKAKDLMEQMKAEIEDEKNELEKKKEDIKRQRDQFEQIKLDLQQVKMEMEQRWHETEK 353
Query: 2123 ---EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFM-- 1959
EQR+ +Q + + ++ + Q REE+ R + + + + + A+++ +
Sbjct: 354 EGLEQRAVIQREKEQLKYLQDEIQRVREEVERNREFSKQEHARISQLRAQALEENNLIEN 413
Query: 1958 --------EKQLQDLENQKETVSKELALS---VSRE----QKLASDLKALSEKEESTKNQ 1824
EK L++++++ E +EL ++ V +E ++ D+++ E ++
Sbjct: 414 KWHDILRKEKDLEEMKHEIERGREELVMNGELVKKEWEKIEQAKVDIQSHMISMEGRVDE 473
Query: 1823 LLIQTEQNKQLELEIEKLYGSLQMKQMENT--LLKDGNEKIYDLCKLLATKSREVQGQQE 1650
+ +TE+ K ++ E+++ +L+ KQ ++T ++ K Y+ + T+ E + + +
Sbjct: 474 IKRETERLKHIKTEMQRDKDALE-KQKDDTRKAKEEAERKRYE----IVTEELEHRARLQ 528
Query: 1649 GILKQDINIEDELARTKEVGRSATDMKK-------------------VNSDAGA---KVS 1536
+ NI E+ R +V ++ +K VN++ A +++
Sbjct: 529 RERDELENIRAEMQRVNDVEKAKILKEKEESIRIREEARQERETTELVNAEIKAEKERLN 588
Query: 1535 GILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVL 1356
E +L + ++ +K E L + N + E+M+ K+E+ + E ++V
Sbjct: 589 QRQEEMLRERQEIERIKHETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVE 648
Query: 1355 RLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNR---- 1188
+Q + ++ +EL+ + + L+ + ++E+ A+ N ++ +ES+ R
Sbjct: 649 EIQKTKEQMEEAKVELEEEREDLERKRDLVSREIEQAEFLRNEILRVKEEMESRWRETET 708
Query: 1187 ---SLKAELHLQAQKAFQIQEE-----RNVVESEHNVL--SSEVENLKSELKESKD---L 1047
L+A+ + ++ +++EE +N+ ES+ ++ ++ LK E++E K +
Sbjct: 709 EEVELRAKTQHELERLEKLREETERSQKNIEESKIELMLWKESLDKLKGEMEEDKHVVIM 768
Query: 1046 EGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNE----NAKLKNEALY 879
+ + E L +E ++ + EK+ LDE+ +RNE +A++++
Sbjct: 769 QMNEAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQHAEMEDWFRV 828
Query: 878 EYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQV 699
+ E N++ +L+ K + + +R ++ E D ++ K LE Q+
Sbjct: 829 VNKEKEEANLAKLAVHEAEMLLKKQM--EESEKRRYEMITEALEQRDEIQKKAEELE-QI 885
Query: 698 QKLSEKAEMFETKSR--EAQQMANKLEEMQQ 612
K ++A K R E + + LE+ QQ
Sbjct: 886 NKEIQRARQELEKMRYFEKESLQKMLEDTQQ 916
Score = 92.0 bits (227), Expect = 1e-15
Identities = 142/718 (19%), Positives = 312/718 (43%), Gaps = 33/718 (4%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEAN----NNLLEQKDNIIVELSHKLQ 2133
E+ R +E ++ +E Q + RQ+ E++ +I+ + NNL+E+ + + L+ K +
Sbjct: 5572 ELEREADEIEKIKLETQHD----RQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNR 5627
Query: 2132 ENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK 1953
+ EE+ ++Q+D +E+ + + E+ +L +++D+ KE + A ++K
Sbjct: 5628 DIEEKIKSIQSDKDMLEK----EKHDLEKTRSELYKVKEDLEKQKE------NTLAEIQK 5677
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEK 1773
+ +DLE E +++E+ +E+++ L + + +N +Q E K+ E+ I K
Sbjct: 5678 EREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQN---LQQELEKEKEI-IMK 5733
Query: 1772 LYGSLQMKQME----NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 1605
L ++Q E T + D E + + K L E++ Q++ + K+ N++
Sbjct: 5734 DRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKS 5793
Query: 1604 TKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVA 1425
E + K++ + K+ + L D++ +KEE +N Q ++
Sbjct: 5794 LDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEET-------QNKRQRLEKM 5846
Query: 1424 LEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNA 1245
E++ K L AE E L A + + +L+R+ L +E + N +L
Sbjct: 5847 TEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSIL-EEMRENISKL--- 5902
Query: 1244 KARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL 1065
K ++N K+ E + + L+ E+ Q K I E+ +ESE + E +N+ +EL
Sbjct: 5903 KEYIDNEKEKSKLREDELKKLQTEVQKQQSK---IDMEKTNIESERAAMIREKQNMMTEL 5959
Query: 1064 -KESKDLEGYFLRLFEILLGQHV-----EVASLDIESCR----FAEEKLMRILDELICLR 915
K+S+D+E +++ EIL + + ++ + D+E+ + E R+ +
Sbjct: 5960 KKKSEDVE---IQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFE 6016
Query: 914 NEN---AKLKNEALYEYHDYERKNV----SGSRAEAMSVLISKSLGNGRANQREFQNKEE 756
NE ++K + + + E+ + R E M+ I K + + N E
Sbjct: 6017 NEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQK-------ERDKINNLIE 6069
Query: 755 DSSGVDLLKNKCTR-LEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXX 579
+++ D++ N+ R +E +++ + +M E + ++ ++L ++++ L
Sbjct: 6070 ETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQ------ 6123
Query: 578 XXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPL------I 417
+ ++KE + + KH+E ++ + D+ T + +
Sbjct: 6124 ---KENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQEL 6180
Query: 416 QXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYW-NRVSHFTKQTQSLQNSVQELQQ 246
+ + D R SE + T M+D + N K + ++ QE+++
Sbjct: 6181 EKEKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEK 6238
Score = 91.7 bits (226), Expect = 1e-15
Identities = 146/693 (21%), Positives = 299/693 (43%), Gaps = 77/693 (11%)
Frame = -1
Query: 2282 EEEKQHTI-ELQENFNALRQKNEDICLKI-------EANNNLLEQKDNIIVELSHKLQEN 2127
E++K++T+ E+Q+ L + NE+I ++ E N ++ D + E+ + QE
Sbjct: 5665 EKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQEL 5724
Query: 2126 EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL 1947
E+++ + D ++ + EL++Q + D + +K D+ ME+Q
Sbjct: 5725 EKEKEIIMKDRSQLD-------LRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQK 5777
Query: 1946 QDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLY 1767
Q++E +++ + + S+ +QK K + E+E++ Q+ I+ E+ EI K+
Sbjct: 5778 QEMEKERDNMDQS-RKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREAD---EISKIK 5833
Query: 1766 GSLQ-----MKQMENTLLKD------------GNEKIYDLCKL-----LATKSRE---VQ 1662
Q +++M L+++ +KI D K+ +A RE ++
Sbjct: 5834 EETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILE 5893
Query: 1661 GQQEGI--LKQDINIEDELARTKE-----------VGRSATDMKKVN--SDAGAKVSGIL 1527
+E I LK+ I+ E E ++ +E +S DM+K N S+ A +
Sbjct: 5894 EMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQ 5953
Query: 1526 EMLLPMK---DDVFSLKEEVLGNINSLRNDAQMVQVALEQMQ--------DTK-----SE 1395
M+ +K +DV +E+L L ND +++ +E +Q D+K E
Sbjct: 5954 NMMTELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDRE 6013
Query: 1394 LFA-EAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMS 1218
F E E Q LQ + D I+ I +E + Q +++ + + KE +
Sbjct: 6014 AFENEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNR 6073
Query: 1217 KNINLESQNRSLKAELHLQAQKAFQIQEERNVVESE-HNV--LSSEVENLKSELKESKDL 1047
K++ L +NR ++ +K IQ +++++E E HN+ SE+ +K +L++ K+
Sbjct: 6074 KDMVLNEKNRDIE-------EKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKEN 6126
Query: 1046 EGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYE--- 876
++ + + E + ++ + EE++ + DEL L+ E L+ E E
Sbjct: 6127 TLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEI 6186
Query: 875 -YHDYERKNVSGSRAEAMSVLISKSLGNGRANQREF-QNKEEDSSGVDLLKNKCTRLEFQ 702
D + ++ S + ++ + + +++ ++KEE ++ + +
Sbjct: 6187 IMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQS 6246
Query: 701 VQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLR 522
+ L + +M + + + ++ NKLE+M+ L +R +K+E R
Sbjct: 6247 RKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELE----------READEIRKIKEETQNER 6296
Query: 521 ---SEMKGELTPSR-SFKHREGSFIKEINIGDE 435
+M EL + SF H KE I D+
Sbjct: 6297 QSLEKMTEELKKEKESFTHLAEDTKKEQEILDK 6329
Score = 91.7 bits (226), Expect = 1e-15
Identities = 154/811 (18%), Positives = 341/811 (42%), Gaps = 62/811 (7%)
Frame = -1
Query: 2282 EEEKQHTI-ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
E++K++T+ E+Q+ + + NE+I ++ + EQ ++ K E ++ ++ +
Sbjct: 6121 EKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQ-------MNQKQDELDQLKTEI 6173
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
QN Q +E+ + +R + + + L ++ + + ++R ++K +++E QK
Sbjct: 6174 QNLQQELEKEKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQK 6233
Query: 1925 ETVSKELALSVSREQKLASDLKALSEKE---ESTKNQLLIQTEQNK-QLELEIEKLYGSL 1758
+ + KE + L DLK + ++ E KN+L EQ K +LE E +++
Sbjct: 6234 QEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKL----EQMKIELEREADEIRKIK 6289
Query: 1757 QMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSAT 1578
+ Q E L+ E++ + + + + +QE + K + E +A ++ +
Sbjct: 6290 EETQNERQSLEKMTEELKKEKESFTHLAEDTKKEQEILDKVKVANESLMADLQKEKSNLE 6349
Query: 1577 DMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEE---------------------VLGNIN 1461
+M++ S V E L +D+++ L+ E ++ N+
Sbjct: 6350 EMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQQREIEKEKINIESERAAIIKNVE 6409
Query: 1460 SLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQD 1281
L++ + E ++ + E E+ Q L+ E D I+ I +E + + Q +++
Sbjct: 6410 DLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELEREADEIEKIKLETQHERQRVEE 6469
Query: 1280 ESQRNAKELWNAKARL--NNVM---------SKNINLESQNRSLKAELHLQAQKAFQIQE 1134
+ + + N + +L N VM K +++ +SL +L + + ++E
Sbjct: 6470 MTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEE 6529
Query: 1133 ERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEE 954
E+N +E L E + + S++KE E L L + E + +I +
Sbjct: 6530 EKNKLEQMKIGLEREADEI-SKIKEETQNERQNLEKMANALKEEREYLAEEI-------K 6581
Query: 953 KLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQRE 774
+ ++LD++ K+ NE+ E++ + E M ISK + +
Sbjct: 6582 RKNQVLDKI--------KVANESTLADLQKEKRIL-----EEMRENISKQI-------ED 6621
Query: 773 FQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETK--------SREAQQMANKLEEM 618
+N++E S L +++ +L+ +VQK + +M +T RE Q M +L++
Sbjct: 6622 IENEKEKSK---LREDELKKLQTEVQKQQSEIDMEKTNIESERAAMIREKQNMMTELKKK 6678
Query: 617 QQTLSDMXXXXXXXXXXXIRVRS-LKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIG 441
+ + R+ LKK+ L+ ++ S S K + +F E
Sbjct: 6679 SEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIERDSESLKLDKEAFENEKEAM 6738
Query: 440 DEDDTPL------IQXXXXXXXXXXXKIDTRTS----ETQEIDTLMDDNRKYWNRV---- 303
+ T L I+ +++ +T+ E +EI+TL+++ +K + +
Sbjct: 6739 KQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIKKKRDIIDESY 6798
Query: 302 SHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDM--NSIEKQLKELNIHVMQLV 129
+ K+ +++++ +L++ I N++EK KE++ M+L
Sbjct: 6799 TEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQQKRNALEKMSKEISRDRMKLE 6858
Query: 128 EHNTRLKKDVKFGFAWANSMHDLNGQEQKLK 36
+ KK+++ MH ++Q+ K
Sbjct: 6859 DE----KKEIQLAREELERMHGDMQRQQEAK 6885
Score = 91.3 bits (225), Expect = 2e-15
Identities = 159/754 (21%), Positives = 300/754 (39%), Gaps = 22/754 (2%)
Frame = -1
Query: 2297 VSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQ 2118
++R E+ K+ L E F AL K E I +++ + EL + ++ E+Q
Sbjct: 2582 LNRELEKIKEKKTILAEEFEALDDKKEMI-------GKEMQRLGKMKAELQKEAEDTEKQ 2634
Query: 2117 RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDL 1938
R + ND ++ E+M Q E++++ +RD+ +L+ DR +EK+ DL
Sbjct: 2635 RRDIDNDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLESDRDTLEKERFDL 2694
Query: 1937 ENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQ-TEQNKQLELEIEKLYGS 1761
E K +++K L ++ ES Q IQ E K+ E+ +E+L +
Sbjct: 2695 EKTK------------------TEMKDLEKQLESQSRQHEIQLVEIQKEREI-LEQLKIN 2735
Query: 1760 LQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIE---DELART---- 1602
L ++ + +D EK + + + E Q ++EGI K + I+ DEL +T
Sbjct: 2736 LSKQKEDLEKERDCFEK--EKADISLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNV 2793
Query: 1601 -KEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVA 1425
KE+ + K++ D K+ I L D ++++ N RN+ +MV
Sbjct: 2794 VKELENNEL-QKQIIEDERDKIEQIKAELQKEAKDTEKQRQDI---ENDRRNNEEMV--- 2846
Query: 1424 LEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNA 1245
++Q+ K + ++ D I+ L+ Q L+ + KE ++
Sbjct: 2847 -IKLQNEKKD--------------IETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDL 2891
Query: 1244 KARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL 1065
K + LESQNR + +L +IQ+ER ++E LS + E+L+ E
Sbjct: 2892 KKTNTEMKDLEKQLESQNRQHEIQL-------AEIQKEREILEQLKLTLSKQKEDLEKE- 2943
Query: 1064 KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLR-NENAKLKNE 888
++ + E + L E L Q + E ++ + +DEL R N +L+N
Sbjct: 2944 RDCFEKEKADISLREELQEQS------EREGIGKTRVRIKKEMDELKQTRLNVVKELENN 2997
Query: 887 ALY-EYHDYERKNVSGSRAEAMSVL---------ISKSLGNGRANQREFQNKEED-SSGV 741
L + + ER + +AE I K N + QN+++D +
Sbjct: 2998 ELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETST 3057
Query: 740 DLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXI 561
D ++++ LE Q Q+L + E + + ++ ++ +++ L
Sbjct: 3058 DRIRDEEANLEVQKQRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQ 3117
Query: 560 RVRSLKKENTRLRSEMKGELTPSRS-FKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXX 384
+ R + ++ S+ K +L R F+ + ++ ++ + I
Sbjct: 3118 KEREILEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGID---------- 3167
Query: 383 XKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXX 204
+TRT QE+D L + + Q + +++ +++Q
Sbjct: 3168 ---NTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAEL--------- 3215
Query: 203 KWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKD 102
EK EL L E T+LKKD
Sbjct: 3216 ------KKEAEKTKLELQNERQNLEEAGTKLKKD 3243
Score = 90.9 bits (224), Expect = 2e-15
Identities = 148/726 (20%), Positives = 304/726 (41%), Gaps = 49/726 (6%)
Frame = -1
Query: 2276 EKQHTIELQENFNALRQ-KNEDICLKIEANNNLLEQKDNIIV-ELSHKLQENEEQRSALQ 2103
++ I+ ++ LR+ K + + +I ++ K +II E + ++N++ + L
Sbjct: 3562 KQNEMIDSEKKKMILREDKLQQMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMTELT 3621
Query: 2102 NDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKE 1923
+ VE TE+E L LL+ DV +L++ L + D +++ + LEN+KE
Sbjct: 3622 KQSEDVEIQMKEVLTEKELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKE 3681
Query: 1922 TVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQ--------NKQLELEIEKL- 1770
V K++ + E + +K ++ E ++ Q ++ N + EI +
Sbjct: 3682 -VLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIK 3740
Query: 1769 YGSLQMKQMENTL------LKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELA 1608
Y QMKQ ++ L +++ +++ +++ E+ +Q + KQ N+ D +
Sbjct: 3741 YQEKQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLKQSELDKQQTNMNDIIE 3800
Query: 1607 RTK-----------EVGRSATDMKKVNSDAGAKVSGILEMLLPMK--DDVFSLKEEVLGN 1467
K E+ +++K D + + E L MK VF ++ L
Sbjct: 3801 TMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVFEEEKNKLEQ 3860
Query: 1466 IN-SLRNDAQMVQVALEQMQDTKSEL---FAEAEIRAQEVLRLQAEVDAIQHILIELKRK 1299
+ L +A ++ E++Q+ + L E + + L + Q IL E+K
Sbjct: 3861 MKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVA 3920
Query: 1298 NQTLQDESQR---NAKEL-WNAKARLNNVMSKNINL---ESQNRSLKAELHLQAQKAFQI 1140
N++L E Q+ N +E+ N + +V +K NL E + L+AE+H Q + +I
Sbjct: 3921 NESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLREDELGQLQAEIHKQQR---EI 3977
Query: 1139 QEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFA 960
++E++ +ESE + VE+L+ ++ I L + E LD E+
Sbjct: 3978 EKEKSNIESERAAIIKIVEDLQHKI---------------ISLDRDAESLKLDREAFENE 4022
Query: 959 EEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQ 780
E L ++ EL +E K+K E HD + R E M+ I+K +
Sbjct: 4023 REVLKQMKTELERETDEIEKIKLET---QHDRQ-------RVEEMTAQITK-------ER 4065
Query: 779 REFQNKEEDSSGVDLLKNKCTR-LEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLS 603
+ N E+++ D++ N+ R +E +++ + +M E + ++ ++L ++++ L
Sbjct: 4066 DKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLE 4125
Query: 602 DMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTP 423
+ ++KE L + KH+E ++ + D+ T
Sbjct: 4126 KQ---------KENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTE 4176
Query: 422 L------IQXXXXXXXXXXXKIDTRTSETQEIDTLMDD-NRKYWNRVSHFTKQTQSLQNS 264
+ ++ ++D R SE + T M+D N K + ++
Sbjct: 4177 IQNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQ 4236
Query: 263 VQELQQ 246
QE+++
Sbjct: 4237 KQEMEK 4242
Score = 89.0 bits (219), Expect = 8e-15
Identities = 124/608 (20%), Positives = 262/608 (43%), Gaps = 47/608 (7%)
Frame = -1
Query: 2303 KEVSRLYEE-EKQHTIELQENFNALRQKNEDICLKIEANNNLLEQK---DNIIVELSHKL 2136
KE+ R +E EK E + L ++ + + LL+ K D + E+ +
Sbjct: 887 KEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLFEMDSER 946
Query: 2135 QENEEQRSALQNDMQSVEQMH-----------AVSQTEREELNR---QLVLLRDDVNHLK 1998
+E E+ R ++N+ + +EQ A Q ++EEL + QLV+ + +N +
Sbjct: 947 KELEQMRFQVENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDTESMNRSR 1006
Query: 1997 EALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLL 1818
E +A DR E + +++ Q+E V+K L + RE+ L L+ E E ++
Sbjct: 1007 E---LARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRL-LRKDMENEREDLEKIR 1062
Query: 1817 IQT-----------EQNKQLELEIEKLYGSLQM-KQMENTLLKDGNEKIYDLCKLLATKS 1674
++T E+ ++ EIE+L+ + Q E + E++ + + +
Sbjct: 1063 VETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRKMEAMKREM 1122
Query: 1673 REVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVF 1494
E++ + + KQ NI+ ++ + ++ N LEM MK D+
Sbjct: 1123 GEIEDMKVELTKQKENIDMKMEHAR--------LEMTN----------LEM---MKADLL 1161
Query: 1493 SLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILI 1314
KE++ + + +++ Q QM+ ++E+ + E +++ +AE++ +QH+
Sbjct: 1162 RQKEDIENQMLAAKSERQ-------QMEVMRTEILKQKEDVERKMELAKAEMEKMQHVKD 1214
Query: 1313 ELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQE 1134
E++++ + L++ Q+ +E+ + + K L+ + + + + +IQ
Sbjct: 1215 EIQKQRKELEERMQKTKREIGEMELMKREMEGKKKELDQRMKLTMRKKEEMERLKMEIQR 1274
Query: 1133 ERNVVE---SEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRF 963
++ +E E E+E +K+E++ ++ E + LR+ E L + E +L I
Sbjct: 1275 AKDDMEFKRVETERQKYEMEQVKAEIQRAR--EEFELRVEERDLEEEKEQMNLTI----- 1327
Query: 962 AEEKLMRILDELICLRNENAKLKNE-------ALYEYHDYERKNVSGSRAEAMSVLISKS 804
+ ++ ++ R K K + + D E N R + + +
Sbjct: 1328 -----INLIQQIEATREMVHKTKFQFENRMAGSQMGTADQEEMNAEMQRL-ILEIEHIRE 1381
Query: 803 LGNGRANQREFQNKE---EDSSGVDLLKNKCTR----LEFQVQKLSEKAEMFETKSREAQ 645
+ G + E QNKE D + LLK + R +E++ +K+ + + E S+ Q
Sbjct: 1382 MLRGLKGEVE-QNKEIMKRDREEIRLLKIEVQRRRREIEYREEKIMREQDELELMSKMGQ 1440
Query: 644 QMANKLEE 621
+ +LEE
Sbjct: 1441 RQREELEE 1448
Score = 89.0 bits (219), Expect = 8e-15
Identities = 153/839 (18%), Positives = 338/839 (40%), Gaps = 89/839 (10%)
Frame = -1
Query: 2273 KQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDM 2094
K+ LQ+ + +E + E N E + +L + +E E+ + Q++
Sbjct: 3649 KKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHER 3708
Query: 2093 QSVEQMHAVSQTERE---ELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL----QDLE 1935
Q VE+M A Q +RE ++N + D+ + ++ + D+ ++ ++ Q+LE
Sbjct: 3709 QRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQELE 3768
Query: 1934 NQKETVSK---ELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEK--- 1773
+KE + K EL L S K +++ + E ++ + QL E+ ++ + EIEK
Sbjct: 3769 KEKEIIMKDRSELDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKH 3828
Query: 1772 --------LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIE- 1620
L L+M +++ + ++ K+ + L ++ E++ +E I + ++E
Sbjct: 3829 DFDQGRNSLDEDLKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEK 3888
Query: 1619 --DELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRND 1446
+EL R KE + K + ++ E L+ S EE+ NI+ D
Sbjct: 3889 MTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTED 3948
Query: 1445 AQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDA-----------IQHILIELKRK 1299
+ + L +D +L AE + +E+ + ++ +++ +QH +I L R
Sbjct: 3949 VKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKIISLDRD 4008
Query: 1298 NQTL-----------------QDESQRNAKELWNAKA---------------------RL 1233
++L + E +R E+ K ++
Sbjct: 4009 AESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITKERDKI 4068
Query: 1232 NNVMS----KNINLESQNRSLKAELHLQAQKAFQIQEERNVVESE-HNV--LSSEVENLK 1074
NN++ K++ L +NR ++ +K IQ +++++E E HN+ SE+ +K
Sbjct: 4069 NNLIEETNRKDMVLNEKNRDIE-------EKIKSIQSDKDMLEKEKHNLEKTRSELYKVK 4121
Query: 1073 SELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLK 894
+L++ K+ ++ L + E ++++ + EE++ + DEL L+ E L+
Sbjct: 4122 EDLEKQKENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEIQNLQ 4181
Query: 893 NEALYE----YHDYERKNVSGSRAEAMSVLISKSLGNGRANQREF--QNKEEDSSGVDLL 732
E E D ++ S + ++ + + N+R+ ++KEE +
Sbjct: 4182 QELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMK-NERKLLDKDKEEMEEQKQEM 4240
Query: 731 KNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVR 552
+ + ++ ++ L E +M + + + ++ NKLE+M+ L R
Sbjct: 4241 EKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQNER 4300
Query: 551 SLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKID 372
++ T+ + + +L + RE + E+ + ++ +Q I
Sbjct: 4301 QSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRILEEMRENI- 4359
Query: 371 TRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSV-QELQQXXXXXXXXXXXXXXKWG 195
+ +T++I+ + ++ + + + Q Q+ + E
Sbjct: 4360 --SKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQNMMT 4417
Query: 194 GIDMNS--IEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEE 24
+ S +E Q+KE+ L + LKKD++ + + + LK+D E
Sbjct: 4418 ELKKKSEDVEIQMKEILTEKELLENDSNLLKKDME---DLKQKLMSIERDSESLKLDRE 4473
Score = 87.8 bits (216), Expect = 2e-14
Identities = 151/751 (20%), Positives = 299/751 (39%), Gaps = 65/751 (8%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQ--KNEDICLK--------IEANNNLLEQKDNIIV 2154
K++++ EE ++ E+++ + + Q K+ D LK IE N LEQ +
Sbjct: 4933 KQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMK---I 4989
Query: 2153 ELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVD 1974
EL + E + + QN+ Q +E+M EEL ++ KE+ + +
Sbjct: 4990 ELEKEADEIRKIKEETQNERQRLEKM-------TEELKKE-----------KESFTHLAE 5031
Query: 1973 DRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQ 1794
D +K L ++ E++ +L S +++ ++ +E E K ++ ++ ++ +Q
Sbjct: 5032 DTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQ 5091
Query: 1793 LELEIEKLYGSLQMKQMENTL--------LKDGNEKIYDLCKLLAT--KSREVQGQQEGI 1644
L+ EI K G ++M++ N +KD K++ L + L + RE + +
Sbjct: 5092 LQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREV 5151
Query: 1643 LKQ---DI-----NIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFS- 1491
LKQ D+ IE T+ + +M K++ ++E KD V +
Sbjct: 5152 LKQIKTDLKRKAEEIEKIKLETQHDRQRVEEMTAQIQKERDKINNLIEE-TNRKDMVLNE 5210
Query: 1490 LKEEVLGNINSLRNDAQMVQVALEQMQDTKSELF-AEAEIRAQEVLRL------------ 1350
+K E+ I ++ +D M++ ++ T+S+L A+ + Q ++L
Sbjct: 5211 IKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEK 5270
Query: 1349 -----QAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRS 1185
E+ I+H ++K+K QDE + E+ N + L + SQ
Sbjct: 5271 MNEKFTIEIHDIKHQEEQMKQK----QDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDL 5326
Query: 1184 LKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-KESKDLEGYFLRLFEILLG 1008
++EL Q I E + + E E K E+ KE D + L E L
Sbjct: 5327 RQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLKM 5386
Query: 1007 QHVEVASLDIESCRFAEEKL--------MRILDELICLRNENAKLKNEALYEYHDYERKN 852
++ L+ E + + K+ +R + E I +N + EAL E ER++
Sbjct: 5387 MKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKE----ERED 5442
Query: 851 VSGSRAEAMSVLISKSLGNG-------RANQREFQNKEEDSSGVDLLKNKCTRLEFQVQK 693
++ + VL + N R + +E S + ++NK L + +
Sbjct: 5443 LAEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDE 5502
Query: 692 LSE-KAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSE 516
L + +AE+ + + ++ N E + D+ SLK + +E
Sbjct: 5503 LRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENE 5562
Query: 515 MKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTL 336
K L ++ RE I++I + + D ++ +I+ ET D +
Sbjct: 5563 -KEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMV 5621
Query: 335 MDD-NRKYWNRVSHFTKQTQSLQNSVQELQQ 246
+++ NR ++ L+ +L++
Sbjct: 5622 LNEKNRDIEEKIKSIQSDKDMLEKEKHDLEK 5652
Score = 85.9 bits (211), Expect = 7e-14
Identities = 124/662 (18%), Positives = 287/662 (43%), Gaps = 38/662 (5%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIE----ANNNLLEQKDNIIVELSHKL 2136
+E ++++++ L E + E++ ++ E AN + + ++ +++EL +
Sbjct: 3234 EEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIELKKTV 3293
Query: 2135 QENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFME 1956
+ + L+N + + + V Q E + L LL+ ++ + + + E
Sbjct: 3294 TDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQLRLRE 3353
Query: 1955 KQLQDLE------------NQKETVSKELAL-----SVSREQKLASDLKALSEKE----E 1839
+L+ L+ N+K ++++ L + R Q+ + + + K+ E
Sbjct: 3354 VELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYASKDRANLE 3413
Query: 1838 STKNQLLIQTEQNKQLELEIEKLYGSLQMK-QMENTLLKDGNEKIYDLCKLLATKSREVQ 1662
K++++ Q Q+++E+ K G ++ + QM NT K+ ++K L + +E++
Sbjct: 3414 KEKSEMI---AQKHQMDIELNKERGLIEERTQMLNTYEKEMDQK----RTALEVEMKELK 3466
Query: 1661 GQQEGILKQDINIEDELARTK-EVGRSATDMKKVNS---DAGAKVSGILEMLLPMKDDVF 1494
++ I ++ +++L + K E+ R A D+KK+ + + + E L KDD+
Sbjct: 3467 YHKQAIQEE----KNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLA 3522
Query: 1493 SLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILI 1314
L E+ + R D +M + + D + E ++R + + + +D+ + +I
Sbjct: 3523 HLAED------TKRKDDEMKVLHESALADIQKEKCNLEQMR-ESMFKQNEMIDSEKKKMI 3575
Query: 1313 ELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKA-FQIQ 1137
+ K Q +Q E R E+ K+ + N + + +N+ L EL Q++ Q++
Sbjct: 3576 LREDKLQQMQAEINRQQTEMDTKKSIIEN---ERAAMTKKNQDLMTELTKQSEDVEIQMK 3632
Query: 1136 E---ERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCR 966
E E+ ++ES+ +L +VENL+ +L +++ E D E
Sbjct: 3633 EVLTEKELLESDRKLLKKDVENLQQKL---------------LIIESDSESLKQDRELLE 3677
Query: 965 FAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSR----AEAMSVLISKSLG 798
+E L ++ +L E K+K E +E E + + M+ I++ +
Sbjct: 3678 NEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIH 3737
Query: 797 NGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEM 618
+ + +++ + K+++ +D LK + L+ Q+L ++ E+ E ++L++
Sbjct: 3738 DIKYQEKQMKQKQDE---LDQLKTEIQNLQ---QELEKEKEIIMKDRSELDLKQSELDKQ 3791
Query: 617 QQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGD 438
Q ++D+ + ++K E +L + + R + + F + N D
Sbjct: 3792 QTNMNDI-------------IETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLD 3838
Query: 437 ED 432
ED
Sbjct: 3839 ED 3840
Score = 85.9 bits (211), Expect = 7e-14
Identities = 148/799 (18%), Positives = 321/799 (40%), Gaps = 47/799 (5%)
Frame = -1
Query: 2279 EEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQ------ 2118
E+++H +E + A ++N + +IE ++ + K NI E+ H+++ EEQ
Sbjct: 4560 EKERHNLEKTRSELARAKENLETQREIE-RKDIEKMKKNISREM-HEIKHQEEQMKQKQD 4617
Query: 2117 -----RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK 1953
++ +QN Q +E+ + R +L+ + L ++ + + ++R ++K
Sbjct: 4618 ELDQLKTEIQNLQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDK 4677
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALS------EKEESTKNQLLIQTEQNKQL 1791
++ E QK+ + KE + L DLK + E+E+S Q+ I+ E+
Sbjct: 4678 DKEETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVIEEEKSKLKQMKIELEREAD- 4736
Query: 1790 ELEIEKLYGSLQ------------MKQMENTLLKDGNEK--IYDLCKL-----LATKSRE 1668
EI K+ Q +K+ L +D K + D K+ LA RE
Sbjct: 4737 --EIRKVKEETQNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRE 4794
Query: 1667 ---VQGQQEGILKQDINIEDE----LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPM 1509
+Q +E I KQ ++E++ R +++ + ++ K S+ + S I +
Sbjct: 4795 RSNLQEMRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNIERERAAI 4854
Query: 1508 KDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAI 1329
DV L+ +++ SL DA+ +++ E ++ K EL Q L+ E D I
Sbjct: 4855 IKDVEDLQSKII----SLDRDAESLKLDREAFENEKEEL-------KQMKTELEREADEI 4903
Query: 1328 QHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKA 1149
+ I +E + + Q +++ + + + N + +LN ++ Q + ++ E H Q
Sbjct: 4904 EKIKLETQHERQRVEEMTADFMETMNNERKQLN---KNKEEMQEQKQEMEKERHDMDQSR 4960
Query: 1148 FQIQEERNVVESEHNVLSSE---VENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDI 978
+ + +++ + V+ E +E +K EL++ D E+ +
Sbjct: 4961 KSLDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEAD-----------------EIRKIK- 5002
Query: 977 ESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLG 798
E + ++L ++ +EL + L + E ++ V+ E++ + K
Sbjct: 5003 EETQNERQRLEKMTEELKKEKESFTHLAEDTKTEKKILDKMKVAN---ESLMADLQKEKS 5059
Query: 797 NGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEM 618
N + + EDS + K K E ++++L +AE+ + + + +N E
Sbjct: 5060 NLEEMRENISKQTEDS---EKEKEKIRLREDELEQL--QAEIHKQQGEIKMEKSNNESER 5114
Query: 617 QQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGD 438
+ D+ + SLK + +E + L ++ R+ I++I +
Sbjct: 5115 AAIIKDVKDLQHKMFSLDRDLESLKLDREAFENE-REVLKQIKTDLKRKAEEIEKIKLET 5173
Query: 437 EDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDD-NRKYWNRVSHFTKQTQSLQNSV 261
+ D ++ KI+ ET D ++++ + ++ L+
Sbjct: 5174 QHDRQRVEEMTAQIQKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEK 5233
Query: 260 QELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAW 81
+L++ ++EKQ K ++L E + K +
Sbjct: 5234 HDLEKTRSKLLRA------------KENLEKQRK------IKLAEIQKEREDLEKMNEKF 5275
Query: 80 ANSMHDLNGQEQKLKVDEE 24
+HD+ QE+++K ++
Sbjct: 5276 TIEIHDIKHQEEQMKQKQD 5294
Score = 85.1 bits (209), Expect = 1e-13
Identities = 119/600 (19%), Positives = 256/600 (42%), Gaps = 34/600 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEE 2121
E+S++ EE + L++ NAL+++ E + +I+ N +L D I V NE
Sbjct: 6547 EISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVL---DKIKV-------ANES 6596
Query: 2120 QRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDD----RAFMEK 1953
+ LQ + + +E+M RE +++Q+ +D+ + KE + D+ + ++K
Sbjct: 6597 TLADLQKEKRILEEM-------RENISKQI----EDIENEKEKSKLREDELKKLQTEVQK 6645
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTE----QNKQLEL 1785
Q +++ +K + E A + +Q + ++LK SE E ++L + E L+
Sbjct: 6646 QQSEIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKK 6705
Query: 1784 EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 1605
++E L L + ++ LK E + + + ++Q Q + I K + E R
Sbjct: 6706 DVEDLQQKLMSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQR 6765
Query: 1604 TKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVA 1425
+E A++ E + + +++ ++ + + +R + + ++
Sbjct: 6766 VEE--------------KTAQIQKEREEINTLVEEIKKKRDIIDESYTEIRKEKEAIESD 6811
Query: 1424 LEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNA 1245
++ KS+ F + + + +Q + +A++ + E+ R L+DE KE+ A
Sbjct: 6812 RSDLEKAKSQTFKQNKNIEIALAEIQQKRNALEKMSKEISRDRMKLEDEK----KEIQLA 6867
Query: 1244 KARLNNV-------------MSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHN 1104
+ L + + I ES + +AE+ LQ + + + R S+ +
Sbjct: 6868 REELERMHGDMQRQQEAKDHLLSGITDESLLKKSEAEIVLQPSQVDKAKPARKTEISDSD 6927
Query: 1103 -----VLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRI 939
V +LK LK+ + E L + +L Q ++ E+KL I
Sbjct: 6928 KQPVFVQQMPEMDLKDALKKDFESEKLDLPKVKDVLPQDQQMK---------LEQKL--I 6976
Query: 938 LDELICLRNENAKLKNEA-LYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQR---EF 771
DE+ L+ A+L+ EA E + +N + + L + N R N+ +
Sbjct: 6977 EDEMDKLKQMRAELQKEADQIEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINIQK 7036
Query: 770 QNKEEDSSGVDLLKNKCTRLEFQV----QKLSEKAEMFETKSREAQQMANKLEEMQQTLS 603
N+++ ++ + K R++ ++ ++L+++ E + E Q+ LEEM+ +S
Sbjct: 7037 VNQQKQATAFQMEKTDFERIKTEIDQANKELADQQEKNKKTITEMQKERETLEEMRANIS 7096
Score = 85.1 bits (209), Expect = 1e-13
Identities = 120/621 (19%), Positives = 270/621 (43%), Gaps = 60/621 (9%)
Frame = -1
Query: 2279 EEKQH-TIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIV----ELSHKLQENEEQR 2115
++K+H T E ++ + ++ KI+ LE++ ++ L+ L+E + Q+
Sbjct: 9764 DKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQIEAENLNKVLEEIKRQQ 9823
Query: 2114 SALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLE 1935
L+ ++ M + REE R+ + + + + + A + +R ++KQ Q+L+
Sbjct: 9824 EKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQKQELQ 9883
Query: 1934 NQKETVSKELALSVSREQKLASDLKALSEKE---ESTKNQLLIQTEQNKQLELEIEKLYG 1764
Q + + + ++ + + ++L E++ E N++L Q + ++ + ++ K +
Sbjct: 9884 KQADDLDMRM---IAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWN 9940
Query: 1763 SLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRS 1584
L + Q E +++ N+ + ++ E+ G++ I K+ +E+ L + +
Sbjct: 9941 KLDVLQNE---MQNENKAMEEI-------KYELDGKRNEINKEQQRLEESL---RAINEE 9987
Query: 1583 ATDMKKVNSDAGAKVSGILEM----------LLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
D++ + +D + I EM L +K ++ K E+ L ND M+
Sbjct: 9988 KGDLEIMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMI 10047
Query: 1433 Q--------------VALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIEL---- 1308
+ +QM+D +SEL + + E +++ + ++ ++ E+
Sbjct: 10048 EKERNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQR 10107
Query: 1307 ---KRKNQTLQDESQRNAKE---LWNAKARLNNVMSKNINLE----SQNRSLK-AELHLQ 1161
K K + L E Q E L + L N + N+E ++ +LK E HLQ
Sbjct: 10108 NDFKLKKEELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQ 10167
Query: 1160 AQK--AFQIQEERNVVESEHNVLSSEVENLKSELKESKD-LEGYFLRLFEILLGQHVEVA 990
K I EE + + + +S+ + K ELK KD LE + +
Sbjct: 10168 RDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRID 10227
Query: 989 SLDIESCRFAEEKL---MRILDELICLRNENAK---LKNEALYEYHDYERKNVSGSRAEA 828
D + + EE L ++ +E CL N K +K +A E+H+ +K + +
Sbjct: 10228 EFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQK-IEELQTLQ 10286
Query: 827 MSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREA 648
++ K + + + ++ D +L++ K T ++ + +KL++ +M E + +
Sbjct: 10287 EQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREK-TEVDHEQKKLNDDIKMIEQEKEDL 10345
Query: 647 QQMANKL----EEMQQTLSDM 597
++M +++ +EM++ S++
Sbjct: 10346 EKMKSEIMTQKQEMEKERSEL 10366
Score = 85.1 bits (209), Expect = 1e-13
Identities = 116/634 (18%), Positives = 264/634 (41%), Gaps = 36/634 (5%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
K S + ++ +Q E E N +RQ + C IE + ++++ + E H++Q +
Sbjct: 11739 KMKSEIMKQRQQMEEERSELENKIRQTYIEKC-DIENSKEIVQKLMVEVEEQKHEIQFQK 11797
Query: 2123 EQ------------------RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLK 1998
E+ +S LQN+ + ++ ++ V + ERE L L + +K
Sbjct: 11798 EELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMK 11857
Query: 1997 EALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLL 1818
+ +EK + QK+ + + L +++ K L ++ + Q+
Sbjct: 11858 SITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVS 11917
Query: 1817 IQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILK 1638
Q E++ E E+++ SL+ + +K E +E + ++E +
Sbjct: 11918 KQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEP--------EEIKKEKEKEEE---E 11966
Query: 1637 QDINIEDELARTKEVGRSATDMKKVNSDAG---AKVSGILEMLLPMKDDVFSLKEEVLGN 1467
Q++ ++ E+ R KE+ + + +++V S+ K++ +M+ K+D+ +K E++
Sbjct: 11967 QEMRVKVEMER-KEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQ 12025
Query: 1466 INSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTL 1287
+ + + ++Q K ++ EI + ++ ++ + IQ EL + Q +
Sbjct: 12026 RQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKI 12085
Query: 1286 QDESQ---RNAKELWNAKARLNNVMSKNINLESQN-RSLKAELHLQAQKAFQIQEERNVV 1119
DE +N E N R+ M + I E + + ++ L + ++ + EE
Sbjct: 12086 ADEQDLLIQNKIEQQNENERIKE-MDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRR 12144
Query: 1118 ESEHNVLSSEVENLKSELKESKDL---EGYFLRLFEILLGQHVE--------VASLDIES 972
+ + +S+++ K +L +DL E + L Q ++ + + +E
Sbjct: 12145 KEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEE 12204
Query: 971 CRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNG 792
+EKL + + E + E + + E D ++N E M L+ K +
Sbjct: 12205 KTEMDEKLQQAIKEYESIIEETNRKRTELEEIEVDQSQQN---KNVETMKDLLEKERKDT 12261
Query: 791 RANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQ 612
+ E Q K+ D + ++++ + E + L E+ ++ E K+ E + + LE+ ++
Sbjct: 12262 EKEREELQ-KQADDLEMQMIEHG-DKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKE 12319
Query: 611 TLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK 510
DM +++ K E ++ E++
Sbjct: 12320 ---DMMKKWNELDGLQKEIQNQKNEMEEIKCELE 12350
Score = 84.3 bits (207), Expect = 2e-13
Identities = 147/702 (20%), Positives = 294/702 (41%), Gaps = 78/702 (11%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQEN---FNALRQKNEDICLKIEANNNLLE------QKDNIIVE 2151
+EV +E +Q T +L+E+ F+ ++KN I +I+ ++ LE K+ I E
Sbjct: 2208 QEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTIFE 2267
Query: 2150 LSHK---LQENE-----EQRSALQNDMQ----SVEQMHAVSQTER--------------- 2052
L + L+ENE +Q LQN ++ VEQM A +R
Sbjct: 2268 LEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTARGRETT 2327
Query: 2051 --EELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQK 1878
EE +++ LR++ ++++ + + E +++ LE + E + K+ + +E +
Sbjct: 2328 ALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAM-KKYKEKLDKEYE 2386
Query: 1877 LASDLKALSEKE-ESTKNQLLIQTE--QNKQLELEIEK--LYGSLQMKQMENTLL-KDGN 1716
+ L EKE + + +L I+ E + K+ ELEI+K +Y M + + ++ K
Sbjct: 2387 DLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKT 2446
Query: 1715 EKIYDLCKLLATKSREVQGQQEGILKQDINI-EDELARTKEVGRSATDMKKVN---SDAG 1548
+++ ++ K + EV+ Q+ +++ ++ I ++E KE R + N S
Sbjct: 2447 DELDEVRKKINADLSEVEKQKSALVQMNLKISQEESYVKKEKDRLKLQENEQNMQMSQLN 2506
Query: 1547 AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRA 1368
AK + + E M+ L E V+ + + + + + +MQ+ A ++
Sbjct: 2507 AKQNELDERQAEMEKQKREL-ENVMDRLEKEKVEITKEKQRVNEMQNEVKRKNASVDLIK 2565
Query: 1367 QEVLRLQAEVDAIQHI----LIELKRKN-------QTLQDESQRNAKELWNAKARLNNVM 1221
QEVLR Q ++ + I L ++K K + L D+ + KE+ +
Sbjct: 2566 QEVLREQDHIENSREILNRELEKIKEKKTILAEEFEALDDKKEMIGKEMQRLGKMKAELQ 2625
Query: 1220 SKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-------- 1065
+ + E Q R + + + ++Q E+ +E+ + + E NL+ +
Sbjct: 2626 KEAEDTEKQRRDIDNDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLESDRD 2685
Query: 1064 ---KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLK 894
KE DLE + + L + +E S E +K IL++ L+ +K K
Sbjct: 2686 TLEKERFDLEKTKTEMKD--LEKQLESQSRQHEIQLVEIQKEREILEQ---LKINLSKQK 2740
Query: 893 NEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEE-DSSGVDLLKNKCT 717
+ E +E++ S E + K G + R Q +E + + ++++K +
Sbjct: 2741 EDLEKERDCFEKEKADISLREELEEQSEKE-GIDKTRVRIKQEMDELEQTRLNVVK-ELE 2798
Query: 716 RLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTL-SDMXXXXXXXXXXXIRVRSLKK 540
E Q Q + ++ + E E Q+ A E+ +Q + +D + ++
Sbjct: 2799 NNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIET 2858
Query: 539 ENTRLRSE------MKGELTPSRSFKHREGSFIKEINIGDED 432
R+R E +K L R +E +K+ N +D
Sbjct: 2859 STDRIRDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEMKD 2900
Score = 84.0 bits (206), Expect = 3e-13
Identities = 140/786 (17%), Positives = 327/786 (41%), Gaps = 26/786 (3%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQ-----ENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHK 2139
+E + EE K IE++ E ++K E+ ++ + E+ D I +L
Sbjct: 11376 EEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKK-EELDQIKSQLERV 11434
Query: 2138 LQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFM 1959
E + ++ L +D + +EQ + + E+ +Q + ++ + L + +R
Sbjct: 11435 RSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLER--- 11491
Query: 1958 EKQLQDLENQKETVSKELA--------LSVSREQKLASDLKALSEKEESTKNQLLIQTEQ 1803
D+EN KE V K + + + +E+ K E+ +N+ +Q E
Sbjct: 11492 ----HDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNEN 11547
Query: 1802 NKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQD--- 1632
+ E++ E +K+ME L K+ E + + + +++ + KQ+
Sbjct: 11548 ERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDL 11607
Query: 1631 INIEDELARTK-EVGRSATDMKKVNSDAGAKVSGILEMLL----PMKDDVFSLKEEVLGN 1467
+N D L + + E+ T +++ + A+VS E L M+++ SL+E +
Sbjct: 11608 MNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKI-K 11666
Query: 1466 INSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTL 1287
I ++ + ++ E+ ++ + + A+ E++ +E+ +++++++ ++ E+ + + L
Sbjct: 11667 IIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRS---EIDHEQKKL 11723
Query: 1286 QDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEH 1107
D+ + +E + + + +M + +E + L+ ++ + I+ + +V+
Sbjct: 11724 NDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQK-- 11781
Query: 1106 NVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL 927
L EVE K E++ K+ LDIE + A+E+ + I ++
Sbjct: 11782 --LMVEVEEQKHEIQFQKE--------------------ELDIERQKIADEQDLLIQNKS 11819
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSS 747
L+NEN ++KN + E ER+ + + M + K ++ E + ++ED
Sbjct: 11820 E-LQNENERIKN--INEVIKKERETL-----KEMEAYLEKEKEEMKSITEETRRQKED-- 11869
Query: 746 GVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXX 567
L+ T + Q Q L + ++ E +E +++ +K +++QQ + +
Sbjct: 11870 ----LEKMSTHINEQKQDLRSQRDLLE---QEREEINHKWKQLQQRIDEFDAQVSKQKEE 11922
Query: 566 XIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXX 387
+ KE+ + E K + ++ E IK+ +E++ Q
Sbjct: 11923 DLPKEKEMKEDRKSLEETKANILEMKT--KAEPEEIKKEKEKEEEE----QEMRVKVEME 11976
Query: 386 XXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQ-TQSLQNSVQELQQXXXXXXXXXXXX 210
+I+ S+ + + + MD +K N +Q + L+ E+ +
Sbjct: 11977 RKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMK------------ 12024
Query: 209 XXKWGGIDMNSIEKQLKELNIHVMQ--LVEHNTRLKKDV--KFGFAWANSMHDLNGQEQK 42
+E++ EL+ + Q L +H+ K++ K H++ Q+++
Sbjct: 12025 -------QRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEE 12077
Query: 41 LKVDEE 24
L ++ +
Sbjct: 12078 LDIERQ 12083
Score = 83.6 bits (205), Expect = 4e-13
Identities = 153/813 (18%), Positives = 320/813 (39%), Gaps = 62/813 (7%)
Frame = -1
Query: 2276 EKQHTI---ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
EKQ I E+Q+ L + NE ++I + EQ + K E ++ ++ +
Sbjct: 5251 EKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQ-------MKQKQDELDQLKTEI 5303
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
QN Q +E+ + +R +L+ + L ++ + + ++R ++K ++ E QK
Sbjct: 5304 QNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQK 5363
Query: 1925 ETVSKELALSVSREQKLASDLKALS------EKEESTKNQLLIQTEQN----KQLELEI- 1779
+ + KE + L DLK + E E+S Q+ I+ E+ ++++ EI
Sbjct: 5364 QEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQ 5423
Query: 1778 ------EKLYGSLQMKQMENTLLKDGNEKIYD---------LCKLLATKSREVQGQQEGI 1644
EK+ +L+ ++ + N ++ D L +L KS ++ +E I
Sbjct: 5424 NERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKS-NLEEMRENI 5482
Query: 1643 LKQDINIEDE----LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEV 1476
KQ ++E++ R E+ + ++ K + + I + DV L+ ++
Sbjct: 5483 SKQTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKI 5542
Query: 1475 LGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKN 1296
+ L DA+ +++ E ++ E E+ Q L+ E D I+ I +E +
Sbjct: 5543 I----CLDRDAESLKLDREAFEN-------EKEVLKQMKTELEREADEIEKIKLETQHDR 5591
Query: 1295 QTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVE 1116
Q +++ + + K+ + K++ L +NR ++ +K IQ +++++E
Sbjct: 5592 QRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIE-------EKIKSIQSDKDMLE 5644
Query: 1115 SEHNVLS---SEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLM 945
E + L SE+ +K +L++ K+ ++ L + E + ++ + EE++
Sbjct: 5645 KEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMN 5704
Query: 944 RILDELICLRNENAKLKNEALYE----YHDYERKNVSGSRAEAMSVLISKSLGNGRANQR 777
+ DEL L+ E L+ E E D + ++ S + ++ + + ++
Sbjct: 5705 QKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERK 5764
Query: 776 EF--------QNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLE- 624
+ + K+E D + L+ +K+ + +MFE + + +QM +LE
Sbjct: 5765 QLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELER 5824
Query: 623 -------------EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSF 483
+Q L M + K ++ EMK S +
Sbjct: 5825 EADEISKIKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMAD 5884
Query: 482 KHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRV 303
RE S ++E+ I ++ +E Q+ + +D + N
Sbjct: 5885 LQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKT--NIE 5942
Query: 302 SHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEH 123
S + QN + EL++ +E Q+KE+ L
Sbjct: 5943 SERAAMIREKQNMMTELKK-------------------KSEDVEIQMKEILTEKELLHND 5983
Query: 122 NTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEE 24
L +DV+ + DL ++LK+D E
Sbjct: 5984 RKLLTRDVE---NLQQKLIDLERDSKRLKLDRE 6013
Score = 83.6 bits (205), Expect = 4e-13
Identities = 128/620 (20%), Positives = 275/620 (44%), Gaps = 63/620 (10%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLE-QKDNIIVELSHKLQEN 2127
+E S L ++ KQ +E + N+ ++ E + +++E + ++ QK+ + +E E
Sbjct: 12031 EERSELDKKIKQTDLEKHDIENS-KEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQ 12089
Query: 2126 E---EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFME 1956
+ + + QN+ + +++M + ERE L V L+ + ++ + + +E
Sbjct: 12090 DLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLE 12149
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSEK--EESTKNQLLI------QTEQN 1800
K D+ QK+ + + L +++ L L ++ E T + +L+ +TE +
Sbjct: 12150 KMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMD 12209
Query: 1799 KQLELEIEKLYGSLQMKQMENTLLKD-------GNEKIYDLCKLLATKSREVQGQQEGIL 1641
++L+ I++ ++ + T L++ N+ + + LL + ++ + ++E +
Sbjct: 12210 EKLQQAIKEYESIIEETNRKRTELEEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQ 12269
Query: 1640 KQDINIEDELAR---TKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLG 1470
KQ ++E ++ +E+ + + D +K + A +L +DD+ KE+++
Sbjct: 12270 KQADDLEMQMIEHGDKEEMSKRSLDEEKKLLEQKANE------ILRQRDDLEKEKEDMMK 12323
Query: 1469 NINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAI------------- 1329
N L + +Q +M++ K EL + +E RL+ ++ +
Sbjct: 12324 KWNELDGLQKEIQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLEIVRVD 12383
Query: 1328 ----QHILIELKRKNQTLQDE-SQRNAKELWNAKARLNNVMSKNI------NLESQNRSL 1182
Q + E++ K + +DE Q AK L + K N SK++ +E +L
Sbjct: 12384 YEKHQQQIEEMRVKTKMERDELDQLMAKMLMDRK---ENERSKDMIGLLKKEMEQTKFNL 12440
Query: 1181 KA---ELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILL 1011
A EL L+ QK +++ + ++E +SEV+ LK + E KD + + E L
Sbjct: 12441 DAQEEELKLEKQKIQNEKKDLEMFKAEIKREASEVKTLKEQQLE-KDTKAFEALKEEHLP 12499
Query: 1010 GQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKL-KNEALYEYHDYERKNVSGSR- 837
GQ V+ + E + E K RIL E + E +L +N+ + E+ + +
Sbjct: 12500 GQFVQQKGGEFERIQIDEVK--RILSE---IHKEKKELERNKQILEHQREALLEIKSKQP 12554
Query: 836 AEAMSVLISKS---------LGNGRANQREFQNKEEDSSGVDLLKNKCTRL---EFQVQK 693
+E + V++ S + + A+Q E K D++K T + E+++ K
Sbjct: 12555 SERLDVILVSSATQTSDLEDIPDVSASQGETVEKH-----TDIIKEYTTSIPKEEYEIDK 12609
Query: 692 LSEKAEMFETKSREAQQMAN 633
L ++ + +RE +MA+
Sbjct: 12610 LKQQGDKKLKSTREDTKMAD 12629
Score = 83.6 bits (205), Expect = 4e-13
Identities = 137/665 (20%), Positives = 282/665 (42%), Gaps = 98/665 (14%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNI---IVELSHKLQE 2130
E+ +L ++ ++ EL++ L+++ + KI+A Q D I I L + +E
Sbjct: 12983 EIQKLRKQYEKEKCELEQIKPDLQKREPE---KIDAE----VQHDEIHGGIDSLKEEREE 13035
Query: 2129 NEEQRSALQNDMQSVEQMHAVSQTEREELNR------QLVL----------LRDDVNHLK 1998
E+ ++ LQN ++ E M + + E++EL + Q+ + L+D++ ++
Sbjct: 13036 IEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIE 13095
Query: 1997 EALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKA-----LSEKEEST 1833
L + + ++E+ ++L +K + + + +L +K +S+ EE
Sbjct: 13096 AILKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKMEERE 13155
Query: 1832 KNQLLIQ------TEQNKQLELEIEKLYG-SLQMKQMENTLLKDGNEKIYDLCKLLATKS 1674
+ I+ E++++++ E E+L ++K+ L + NE + K
Sbjct: 13156 AERKTIERVMDEMAEEHEKIKKEREELVNMEEEIKKQRRVLEESMNE--------MTKKK 13207
Query: 1673 REVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGIL----EMLLPMK 1506
E+Q ++ + KQ +ED +A S D+ S + IL E + MK
Sbjct: 13208 SELQHERSELYKQKQQLEDMIA-----SESKRDVDTERSRQDKEDEQILKREREEIADMK 13262
Query: 1505 DDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSE--------LFAEAEIRA------ 1368
D + KE+V + + + ++ Q+ D K E L+ + EI+
Sbjct: 13263 DQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEIQVKTNALE 13322
Query: 1367 ---QEVLRLQAEVDA--IQH---------ILIELKRKNQTLQDESQRNAKELWNAKARL- 1233
Q++ + + V+A IQH ++ E KRK + + E QR +++ + K RL
Sbjct: 13323 KMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFEDIESVKVRLV 13382
Query: 1232 ---NNVMSKNINLESQNRSLKAELHLQAQKAF-----QIQEERNVVESEHNVLSSEVENL 1077
N + N L++++ L+ L + QK F ++Q ER +E + L + L
Sbjct: 13383 TESNQIDKMNSELKTRSEELE-NLIKKQQKEFETKENEMQRERKALEKMNAELERKSTEL 13441
Query: 1076 KSELKE----SKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEK---------LMRIL 936
K+++++ DL+ + E+ E + L E + ++K + +
Sbjct: 13442 KNKIEKVTVWEADLQKEKNKTEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEM 13501
Query: 935 DELICLRNENAKLKNEAL----YEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQ 768
+ L CLRNE K L E H+ ++ ++E S+ K ++ E +
Sbjct: 13502 ENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTE-IQSEKESIEEEKKTLKQLKDENESK 13560
Query: 767 NKEEDSSGVDLLKNKCTRLEFQVQK---------LSEKAEMFETKSREAQQMANKLEEMQ 615
+ D++ + K +L Q +K L KAE + + R+A Q+ +++ +
Sbjct: 13561 RTQLDNT---IEKMNMDKLSIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDA 13617
Query: 614 QTLSD 600
+ L D
Sbjct: 13618 KILDD 13622
Score = 81.6 bits (200), Expect = 1e-12
Identities = 148/839 (17%), Positives = 336/839 (40%), Gaps = 86/839 (10%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNII----VELSHKLQENEEQR 2115
EE+K+ + + +F+ R ++ ++ + E++ N + +EL + E + +
Sbjct: 3817 EEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIK 3876
Query: 2114 SALQNDMQSVEQM------------HAVSQTER--------------------------E 2049
+QN+ QS+E+M H T++ E
Sbjct: 3877 EEIQNERQSLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEKSNFE 3936
Query: 2048 ELNRQLVLLRDDVNHLKEALSMAVDD----RAFMEKQLQDLENQKETVSKELALSVSREQ 1881
E+ + +DV + KE L + D+ +A + KQ +++E +K + E A + +
Sbjct: 3937 EMRENISKQTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVE 3996
Query: 1880 KLASDLKALSEKEESTK-NQLLIQTEQN--KQLELEIEKLYGSLQMKQMENTLLKDGNEK 1710
L + +L ES K ++ + E+ KQ++ E+E+ ++ ++E + ++
Sbjct: 3997 DLQHKIISLDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLET---QHDRQR 4053
Query: 1709 IYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGI 1530
+ ++ + + ++ E ++D+ + ++ +E +S K + +
Sbjct: 4054 VEEMTAQITKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKT 4113
Query: 1529 LEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRL 1350
L +K+D+ KE L I R D LE+M + + E + + +++ +
Sbjct: 4114 RSELYKVKEDLEKQKENTLAEIQKERED-------LEKMNENITIEMHEIKHQEEQMKQK 4166
Query: 1349 QAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAEL 1170
Q E+D ++ E++ Q L+ E + K+ R + + + N+ ++K E
Sbjct: 4167 QDELDQLK---TEIQNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNER 4223
Query: 1169 HLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESK------DLEGYFLRLFEILLG 1008
L + +++E++ +E E + + +++L +LK K + E L + L
Sbjct: 4224 KLLDKDKEEMEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQ 4283
Query: 1007 QHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEA 828
+ + E + + L ++ LI R + L E + V+ + A
Sbjct: 4284 READEIRKIKEETQNERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMA 4343
Query: 827 MSVLISKSLGNGRAN-QREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETK--- 660
+ L R N ++ ++ E + L +++ +L+ +VQK + +M +T
Sbjct: 4344 DLQREKRILEEMRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIES 4403
Query: 659 -----SREAQQMANKLEEMQQTLS-DMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELT 498
RE Q M +L++ + + M LKK+ L+ ++
Sbjct: 4404 ERAVMIREKQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLMSIER 4463
Query: 497 PSRSFKHREGSFIKEINIGDEDDTPL------IQXXXXXXXXXXXKIDTRTSETQ----E 348
S S K +F E + + T L I+ +++ +T++ Q E
Sbjct: 4464 DSESLKLDREAFGNEKEVLKQMKTDLQIQADEIEKIKLETQHDRQRVEEKTAQIQKDRDE 4523
Query: 347 IDTL-MDDNRK--YWNRVSH-FTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMN 180
I+ L ++ NRK N + ++ +S+Q+ L++ + +
Sbjct: 4524 INNLIVETNRKDMVLNEMDRDIEEKIKSIQSDKDMLEK-------------------ERH 4564
Query: 179 SIEKQLKEL-----NIHVMQLVEHN--TRLKKDVKFGFAWANSMHDLNGQEQKLKVDEE 24
++EK EL N+ + +E ++KK++ + MH++ QE+++K ++
Sbjct: 4565 NLEKTRSELARAKENLETQREIERKDIEKMKKNI------SREMHEIKHQEEQMKQKQD 4617
Score = 81.6 bits (200), Expect = 1e-12
Identities = 136/672 (20%), Positives = 287/672 (42%), Gaps = 56/672 (8%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNII----VELSHKLQENEEQR 2115
EE+KQ + ++N + R+ ++ K++ + E++ N + +EL + E + +
Sbjct: 5774 EEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIK 5833
Query: 2114 SALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLE 1935
QN Q +E+M EEL R+ KE+L+ +D +K L +++
Sbjct: 5834 EETQNKRQRLEKM-------TEELIRE-----------KESLAHLAEDTKTEKKILDEMK 5875
Query: 1934 NQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQ 1755
E+ +L S +++ ++ L E ++ K + ++ ++ K+L+ E++K +
Sbjct: 5876 VANESSMADLQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKID 5935
Query: 1754 MKQ--MENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSA 1581
M++ +E+ EK ++ L KS +V+ Q + IL E EL
Sbjct: 5936 MEKTNIESERAAMIREK-QNMMTELKKKSEDVEIQMKEIL-----TEKELLH-------- 5981
Query: 1580 TDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQM---VQVALEQMQ 1410
D K + D V + + L+ ++ D LK + N QM +Q+ ++++
Sbjct: 5982 NDRKLLTRD----VENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEIE 6037
Query: 1409 DTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLN 1230
K E + + + ++Q E D I +++ E RK+ L ++++ +++ + ++ +
Sbjct: 6038 KIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKD 6097
Query: 1229 NVMSKNINLESQNRSL-KAELHLQAQK---AFQIQEERNVVE------------------ 1116
+ + NLE L K + L+ QK +IQ+ER VE
Sbjct: 6098 MLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEE 6157
Query: 1115 ------SEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAE- 957
E + L +E++NL+ EL++ K++ F++ + LD + +
Sbjct: 6158 QMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQFDL------RQSELDKQQTNMNDI 6211
Query: 956 -EKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQ 780
E + +L + E + K E E HD+++ S + + + + K + N+
Sbjct: 6212 METMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDK-DLKMMKLQKQVFEEEKNK 6270
Query: 779 REFQNKEEDSSGVDLLK------NKCTRLEFQVQKLSEKAEMF---ETKSREAQQMANKL 627
E E + ++ K N+ LE ++L ++ E F +++ Q++ +K+
Sbjct: 6271 LEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFTHLAEDTKKEQEILDKV 6330
Query: 626 E--------EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHRE 471
+ ++Q+ S++ V + KKEN RLR + +L + +K +
Sbjct: 6331 KVANESLMADLQKEKSNLEEMRENISKQTEDVEN-KKENLRLREDELWQL-QAEIYKQQR 6388
Query: 470 GSFIKEINIGDE 435
++INI E
Sbjct: 6389 EIEKEKINIESE 6400
Score = 79.7 bits (195), Expect = 5e-12
Identities = 114/611 (18%), Positives = 267/611 (43%), Gaps = 43/611 (7%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
K S L + +Q E E +++ N + KIE N ++E+ + E + + +
Sbjct: 10056 KMKSELMTQRQQMEDERSELDQKIKEANTEKD-KIEKNKEIVERLMAEVEEQRNDFKLKK 10114
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNH----LKEALSMAVDDRAFME 1956
E+ + + ++ + + A +TE + + Q+ + + V + LKE + D+ ++
Sbjct: 10115 EELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIK 10174
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQ-----NKQL 1791
+++ QKE + K ++ ++ +++ + K E+E N Q +Q + Q+
Sbjct: 10175 SIIEETSRQKEDLEK-ISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQV 10233
Query: 1790 ELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKL-------LATKSREVQGQQEGILKQD 1632
+ E+ + + + E L++ N KI ++ + K E+Q QE I+K+
Sbjct: 10234 RKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEK 10293
Query: 1631 INIEDELARTKEVGRSATDMKKVNSD----------AGAKVSGILEMLLPMKDDVFSLKE 1482
E A T ++ D+ ++ S+ K++ ++M+ K+D+ +K
Sbjct: 10294 EKAE---AMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKS 10350
Query: 1481 EVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKR 1302
E++ + + + ++Q K ++ EI + + ++ + IQ EL
Sbjct: 10351 EIMTQKQEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDI 10410
Query: 1301 KNQTLQDESQ---RNAKELWNAKARLNNVMSKNINLESQNRSLK-AELHLQAQKAFQIQE 1134
+ Q + DE +N EL N R+ N+ N ++ + +LK E HL+ +K E
Sbjct: 10411 ERQKIADEQDLLIQNKSELQNENERIRNI---NEVIKKERETLKEMEAHLEKEK-----E 10462
Query: 1133 ERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEE 954
E + E ++E + +++KE + L+ Q ++ + E
Sbjct: 10463 EMKSITEETRRQKEDLEKMSTDIKEQN----------QDLMKQR-DLLEQEKEDINHEWT 10511
Query: 953 KLMRILDELICLRNENAKLKNEALYEYHDY--ERKNVSGSRAEAMSVLISKSLGNGRANQ 780
+L + +DE + +K K E L + + ERK++ ++A + + L + + +
Sbjct: 10512 QLQQRIDEFDA---QVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEK 10568
Query: 779 REFQNKEE-------DSSGVDLLKNKCTR----LEFQVQKLSEKAEMFETKSREAQQMAN 633
+ + +EE D +D +K++ R ++ + +KL++ ++ E + + ++M +
Sbjct: 10569 EKEEEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKS 10628
Query: 632 KLEEMQQTLSD 600
++ + +Q + +
Sbjct: 10629 EIMKQRQQMEE 10639
Score = 79.7 bits (195), Expect = 5e-12
Identities = 106/593 (17%), Positives = 267/593 (45%), Gaps = 25/593 (4%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLE-QKDNIIVELSHKLQEN 2127
+E S L + KQ IE + N+ ++ + + +++E + ++ QK+ + +E E
Sbjct: 10639 EERSELENKIKQTYIEKCDIENS-KEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQ 10697
Query: 2126 E---EQRSALQNDMQSVEQMHAVSQTERE---ELNRQLVLLRDDVNHLKEALSMAVDDRA 1965
+ + +S LQN+ + + ++ + + ERE E+ L ++++ + E +D
Sbjct: 10698 DLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRLKED-- 10755
Query: 1964 FMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLEL 1785
+EK D+ Q + + + L +++ K L ++ + Q+ Q EQ+ E
Sbjct: 10756 -LEKMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEK 10814
Query: 1784 EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 1605
+++ SL+ + +K E K +E + ++E +++I + E R
Sbjct: 10815 GMKEDRKSLEETKANVIEMKTKAEPEE------IKKEKEKENEEEEEEEEEIRVIVETER 10868
Query: 1604 TKEVGRSATDMKKVNSDAG---AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
KE+ + +++++V S+ K++ ++M+ K+D+ +K E++ + + +
Sbjct: 10869 -KELYQIKSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSEL 10927
Query: 1433 QVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQ---RNA 1263
++Q K ++ EI + ++ ++ + IQ EL + Q + DE +N
Sbjct: 10928 DNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQNK 10987
Query: 1262 KELWNAKARLNNVMSKNINLESQNRSLK-AELHLQAQKAFQIQEERNVVESEHNVLSSEV 1086
+L N R+ V + ++ + +L+ E+HL+ +K +E R+++E E ++
Sbjct: 10988 AKLQNENERIKKV---DEEIKKERETLREMEIHLKKEK----EELRSIIE-ETQRRKEDL 11039
Query: 1085 ENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNEN 906
E + +++ E K + L ++ + E +L + +DE +
Sbjct: 11040 EKMSTDINEQK-----------LHLKNQRDLLEQEREEINHEMTQLQQRIDEFDA---QV 11085
Query: 905 AKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDL--- 735
+K + + + + ERK++ ++A + + L ++E +++EE V++
Sbjct: 11086 SKQREDLTKQEMEEERKSLEETKARIIEMKTKAEL-QEIMQEKEEEDEEEMRVIVEMERE 11144
Query: 734 --------LKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSD 600
LK + ++ + +KL++ ++ E + + ++M +++ +Q + +
Sbjct: 11145 ELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEE 11197
Score = 77.4 bits (189), Expect = 3e-11
Identities = 122/621 (19%), Positives = 274/621 (44%), Gaps = 65/621 (10%)
Frame = -1
Query: 2273 KQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQ-ENEEQRSALQND 2097
KQ EL++ L ++ E+ E ++E + + I ++ +L+ E E+ + LQN+
Sbjct: 3174 KQEMDELEKTRQNLAKEQENN----ELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNE 3229
Query: 2096 MQSVEQMHAVSQTER-------EELNRQLVLLRD-----DVNHLKEALSMAVDDRAFME- 1956
Q++E+ + +R EEL R+ V+L + ++ + + +R +E
Sbjct: 3230 RQNLEEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIEL 3289
Query: 1955 -KQLQDLENQKETVSKELALSVSREQKLASDLKALSE-----KEESTKNQLLI--QTEQN 1800
K + D+ KE + +L + + ++++A + K+ ++ Q+ I +TEQ
Sbjct: 3290 KKTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQL 3349
Query: 1799 KQLELEIEKLYGSLQMKQMENTLLKDGNEK--IYDLCKLLATKS------REVQGQQEGI 1644
+ E+E+E+L + +Q E + N K I + +L K+ REV E
Sbjct: 3350 RLREVELEQLQALIYRQQDE----IEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYA 3405
Query: 1643 LKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNI 1464
K N+E E +++ + + ++N + G + +ML + ++ + + +
Sbjct: 3406 SKDRANLEKE--KSEMIAQKHQMDIELNKERGL-IEERTQMLNTYEKEMDQKRTALEVEM 3462
Query: 1463 NSLRNDAQMVQVALEQMQDTKSELFAEAE--IRAQEVLR------------LQAEVDAIQ 1326
L+ Q +Q ++Q K EL EA+ + +E R L+ E D +
Sbjct: 3463 KELKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLA 3522
Query: 1325 HILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAF 1146
H+ + KRK+ ++ + ++ K L + S K ++ L+ K
Sbjct: 3523 HLAEDTKRKDDEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQ 3582
Query: 1145 QIQEE-----------RNVVESEHNVLSSEVENLKSEL-KESKDLEGYFLRLFEILLGQH 1002
Q+Q E ++++E+E ++ + ++L +EL K+S+D+E +++ E+L +
Sbjct: 3583 QMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVE---IQMKEVLTEKE 3639
Query: 1001 V-----EVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSR 837
+ ++ D+E+ ++KL+ I + L+ + L+NE E + ++ G
Sbjct: 3640 LLESDRKLLKKDVEN---LQQKLLIIESDSESLKQDRELLENEK--EVLKQMKTDLQGEA 3694
Query: 836 AEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTR----LEFQVQKLSEKAEMF 669
E + + R + Q ++D + + + TR +++Q +++ +K +
Sbjct: 3695 EEIEKIKLETQHERQRVEEMTAQ-IQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDEL 3753
Query: 668 ETKSREAQQMANKLEEMQQTL 606
+ E Q + +LE+ ++ +
Sbjct: 3754 DQLKTEIQNLQQELEKEKEII 3774
Score = 77.0 bits (188), Expect = 3e-11
Identities = 132/656 (20%), Positives = 271/656 (41%), Gaps = 38/656 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQ-HTIELQENFNALRQKNEDIC-LKIEANNNLLEQK--DNIIVELSHKLQ 2133
E S++ +EK+ E+Q + Q E++ LK E N ++ + + EL K Q
Sbjct: 8667 EESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQ 8726
Query: 2132 ENEEQRSALQNDMQSVEQMHAVSQTERE--ELNRQLVLLR---------DDVNHLKEALS 1986
E E R LQ + + +EQ+ E+E E++R+LV DV KE L
Sbjct: 8727 EEESMREILQKEKEELEQLKKDINREKEDIEISRELVESEIYEGEVKGFTDVQKYKEELQ 8786
Query: 1985 MAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALS---EKEESTKNQLLI 1815
+ ++ ++ L+ L + + + + L + K ++L+ ++ +K E +
Sbjct: 8787 IVTEELLTKKRNLEQLNSDVQHLMQTLEEVDIQYIKKKAELEHITSEIQKREQILEKQKK 8846
Query: 1814 QTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKL-----------LATKSRE 1668
+ E+N + EIE + +L+ ME ++ EK + + L + E
Sbjct: 8847 KLEENGWIIEEIEMMKVTLESINMEILQKREDMEKEKENLRREKQETELFRGELQRQRDE 8906
Query: 1667 VQGQQEGI--------LKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLP 1512
V+ ++ + LK D + A ++ + +M+ + AK++ L
Sbjct: 8907 VESSRQALIMEKDQFKLKIDHQRNEMSAAFEKEHKRLENMENDLENQRAKLAESLNDAAK 8966
Query: 1511 MKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDA 1332
M+ + +K E+ + QMV+ +++ K E+ + + +LQ + +
Sbjct: 8967 MEQKLQQMKNELNKEKEQVEEMKQMVKTERVKIEQEKEEMRKQTQEIEDGHEKLQKKTEI 9026
Query: 1331 IQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSL-KAELHLQAQ 1155
+L + ++ L+D S + + + ++ N +E++ RSL + LQ
Sbjct: 9027 ADKLLQDANSESDRLKDLSMK-------LQMQRQDIEKTNTEMETKKRSLDRMSRELQDD 9079
Query: 1154 KAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIE 975
K +++ +R+ E + L + E L ++E++DLE L+ E E+A DIE
Sbjct: 9080 K-IRLKNDRDAYEKDMTHLELKREEL---VRETEDLERKILQQRE-----QDEMAKRDIE 9130
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGN 795
+ A E +M++ +++ RNE AK E +NV R + + + +
Sbjct: 9131 NQTEALE-VMKV--DILKKRNEFAK------------EMENVHSERQKLLLLQGALQSQE 9175
Query: 794 GRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQ 615
R F +++ +C + + AEM ET + E + +EE+Q
Sbjct: 9176 SELENRVFMEEQKHLKQAKAETEECRK---------QLAEMSETVTTEQNEYRKLIEELQ 9226
Query: 614 QTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEIN 447
+ + ++ KK+ ++S ++ +L S +H + + E N
Sbjct: 9227 REKEQL-------EISKNQIEQEKKDLQNMKSNLERQL---ESLRHEKANVEDEKN 9272
Score = 76.3 bits (186), Expect = 6e-11
Identities = 85/437 (19%), Positives = 201/437 (45%), Gaps = 27/437 (6%)
Frame = -1
Query: 2279 EEKQHTIELQENFNALRQKN-EDICLKIEANNNLLEQKDNIIVELSHKL-----QENEEQ 2118
E ++H +E ++ +QK EDI I++ ++LE++ + + +LSH L +E EE
Sbjct: 13927 EAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEEL 13986
Query: 2117 RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEAL------SMAVDDRAFME 1956
L+ + +E + ++E++ + R+ R ++ LKE + ++ D+ ++
Sbjct: 13987 ERLLEKERDDIENCKKIIESEKQSIERE----RAELKRLKEEVEVQHERTLLQQDKNMIQ 14042
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIE 1776
K+ + LE +K ++E+ ++ +S+L L+++ E+ + + E
Sbjct: 14043 KEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQE---------------E 14087
Query: 1775 KLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILK---QDINIE---DE 1614
+L+G + ++E+ L K+ D+ + K ++ Q+ LK +D + DE
Sbjct: 14088 ELHGLPEEIEIEDHLKKED-----DVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDE 14142
Query: 1613 LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
+ +T E + A + + AK ++++ + +V +++ + I L ++
Sbjct: 14143 ITKTDERRQRALEETVATT---AKQPIVIKLEDTLTSEVQEMRDHLNNEIKELARMKTIM 14199
Query: 1433 QVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKEL 1254
++ +Q++ KS++ + E + + E + L++L + L + + KE+
Sbjct: 14200 KMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLDKKNKEI 14259
Query: 1253 WN---------AKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNV 1101
N A+ V+ K +N L+ + Q ++ +IQ + +V +E +
Sbjct: 14260 ENNTETFLKKIAQLETTIVLMKKDKENIENELLQLK---QIEQEREIQRKADVTSTEKEM 14316
Query: 1100 LSSEVENLKSELKESKD 1050
+ +V K+EL++SK+
Sbjct: 14317 YTEKV-TYKTELEDSKE 14332
Score = 75.5 bits (184), Expect = 1e-10
Identities = 134/627 (21%), Positives = 266/627 (42%), Gaps = 97/627 (15%)
Frame = -1
Query: 2189 NNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDV 2010
N LE + E+ ++ + E+ R +L DMQ +EQM + E+EE+ Q + ++
Sbjct: 2011 NRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEK 2070
Query: 2009 NHLKEALSMAVDDR------AFMEKQ-LQD--LENQKETVS-KELALSVSREQKLASDLK 1860
+ L+ L +D EKQ L+D +E QKE +A R+++ ++
Sbjct: 2071 DKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIR 2130
Query: 1859 ALSEKEEST--------KNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIY 1704
EK+E T + + I Q + ++ +I+ + Q E + E+I
Sbjct: 2131 VGIEKQEITFKDLKADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLVEEIE 2190
Query: 1703 DLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKV---SG 1533
K L EV +++ + + +E E ++ +E + K+ N+ A++ S
Sbjct: 2191 KRTKALDEMQMEVDKERQEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESD 2250
Query: 1532 ILEML---LPMKDDVFSLKEEVLG-----------NINSLRNDAQMVQVALEQMQDTKSE 1395
LE+ + + +F L++E LG I+ L+N +M +V +EQMQ K +
Sbjct: 2251 NLELQSENISKERTIFELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQ 2310
Query: 1394 LFAEAEI--------------RAQEVLRLQAEVDAIQ----HI-----LIELKRKNQTLQ 1284
+AE + QE+ L+ E + ++ H+ L E + K+ ++
Sbjct: 2311 QRKKAEYVKTARGRETTALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEME 2370
Query: 1283 DESQRNAKELWNAK-----------ARLNNVMSKNINLESQN-RSLKAELHLQA----QK 1152
+E+ + KE + + + M + +E++N K EL +Q +
Sbjct: 2371 NEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTE 2430
Query: 1151 AFQIQEERNVVE-SEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIE 975
+ ++ ++ VVE S+ + L + + ++L E + + +++ + + Q + +
Sbjct: 2431 TYMLETQKPVVEKSKTDELDEVRKKINADLSEVEKQKSALVQM-NLKISQEESYVKKEKD 2489
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGN 795
+ E + + +L +NE + +A E E +NV R E V I+K
Sbjct: 2490 RLKLQENEQNMQMSQLNAKQNELD--ERQAEMEKQKRELENVM-DRLEKEKVEITKE--K 2544
Query: 794 GRANQREFQNKEEDSSGVDLLKNKCTR-----------LEFQVQKLSEK----AEMFETK 660
R N+ + + K +++S VDL+K + R L +++K+ EK AE FE
Sbjct: 2545 QRVNEMQNEVKRKNAS-VDLIKQEVLREQDHIENSREILNRELEKIKEKKTILAEEFEAL 2603
Query: 659 -------SREAQQMANKLEEMQQTLSD 600
+E Q++ E+Q+ D
Sbjct: 2604 DDKKEMIGKEMQRLGKMKAELQKEAED 2630
Score = 75.5 bits (184), Expect = 1e-10
Identities = 144/718 (20%), Positives = 298/718 (41%), Gaps = 33/718 (4%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQE-N 2127
K + +L +E + +L N + + N D L I+ + LE+ I +L K ++ +
Sbjct: 13548 KTLKQLKDENESKRTQLD---NTIEKMNMDK-LSIQREKDSLEE---IKADLQRKAEKLD 13600
Query: 2126 EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL 1947
EE R A+Q Q +++ +L DD +E SM RA +E+Q
Sbjct: 13601 EEMRKAVQITSQ---------------ISQDAKILDDDREKEEELRSM----RADIERQA 13641
Query: 1946 QDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLY 1767
+ LE+ + + E + + K +DL +++ +N L +Q EL EK
Sbjct: 13642 KILESDVQLLQTE--KEILEKSKTENDLLREDLEKQRKRNDLTLQ-------ELRKEK-- 13690
Query: 1766 GSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGR 1587
+ ++QM + K+ + + L ++ K E++ ++ + +Q + D+L E+ +
Sbjct: 13691 --MALEQMITDITKE-KDAVASLQNEVSLKQHELKNKETELDEQRKEM-DDLRMQLEMRQ 13746
Query: 1586 SATDMKKVNSDA----GAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALE 1419
++T+ ++ D K+ LE + + D+ ++ + +N +
Sbjct: 13747 NSTNKQQQEVDVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAV 13806
Query: 1418 QMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKA 1239
Q D + + + + V + + E+D + +I+ K + Q+L E + +E+ +A
Sbjct: 13807 QQTDELEKFTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRA 13866
Query: 1238 RLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKE 1059
++ ++ +L + +K + + Q A + E++ VE + N+ + +N EL+
Sbjct: 13867 QIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNL--QKQKNELEELRN 13924
Query: 1058 SKDLEGYFLRLFEILLG---QHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNE 888
+ + E + + +I+L + VE I+S R EK L++L + NE + + E
Sbjct: 13925 TIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQE 13984
Query: 887 ALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLE 708
L + ER ++ + S +S+ RA + + + E LL+ ++
Sbjct: 13985 ELERLLEKERDDIENCKKIIESE--KQSIERERAELKRLKEEVEVQHERTLLQQDKNMIQ 14042
Query: 707 FQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVR-------- 552
EK + K+R +++ N EE+++ S++
Sbjct: 14043 ------KEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQEEELHGLPEEI 14096
Query: 551 ----SLKKENTRLRSEM--KGELTPSRSFKHREGS-------FIKEINIGDEDDTPLIQX 411
LKKE+ LR E+ K + S+ F+ + S + EI DE ++
Sbjct: 14097 EIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRALEE 14156
Query: 410 XXXXXXXXXXKI---DTRTSETQEIDTLMDDNRKYWNRVSHFTK-QTQSLQNSVQELQ 249
I DT TSE QE+ +++ K R+ K + L+ + ++Q
Sbjct: 14157 TVATTAKQPIVIKLEDTLTSEVQEMRDHLNNEIKELARMKTIMKMEKDQLKQAKSDIQ 14214
Score = 75.1 bits (183), Expect = 1e-10
Identities = 109/585 (18%), Positives = 249/585 (42%), Gaps = 36/585 (6%)
Frame = -1
Query: 2156 VELSHKLQENEEQ-RSALQNDMQSVE-QMHAVSQ--TEREELNRQLVLLRDDVNHLKEAL 1989
+E KL E +Q R+ + N Q ++ Q +++ TE+ +L R + ++ +++H++E +
Sbjct: 145 IEQIEKLWEGTKQERTEIDNMKQKIQRQQDEITRMTTEKGQLERTITHMKAEIDHIRERM 204
Query: 1988 SMAVD----DRAFMEKQLQDLENQKETVSKELALSVSREQKL-------ASDLKALSEKE 1842
+ +R +E+ DL+ ++ ++ ++ ++ Q L + L
Sbjct: 205 DRNKEEVNRERERVEQMRSDLQAEQSSLQQKRDEIMTERQNLEMIRYETLRQQEELESNR 264
Query: 1841 ESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQ 1662
ESTK+++ + ++++I ++ + Q L++ +I D L K +++
Sbjct: 265 ESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLMEQMKAEIEDEKNELEKKKEDIK 324
Query: 1661 GQQEGILKQDINIEDELARTK-EVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLK 1485
Q++ Q I+ +L + K E+ + + +K + A + E L ++D++ ++
Sbjct: 325 RQRD----QFEQIKLDLQQVKMEMEQRWHETEKEGLEQRAVIQREKEQLKYLQDEIQRVR 380
Query: 1484 EEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELK 1305
EEV N R ++ + Q++ E E + ++LR + +++ ++H E++
Sbjct: 381 EEVERN----REFSKQEHARISQLRAQALEENNLIENKWHDILRKEKDLEEMKH---EIE 433
Query: 1304 RKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERN 1125
R + L + KE + ++ S I++E + +K E ++Q +++
Sbjct: 434 RGREELVMNGELVKKEWEKIEQAKVDIQSHMISMEGRVDEIKRETERLKHIKTEMQRDKD 493
Query: 1124 VVESE---------------HNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVA 990
+E + + +++ E+E+ +E +LE + + + ++
Sbjct: 494 ALEKQKDDTRKAKEEAERKRYEIVTEELEHRARLQRERDELENIRAEMQRVNDVEKAKIL 553
Query: 989 SLDIESCRFAEE-KLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLI 813
ES R EE + R EL+ NA++K E ER N R E M +
Sbjct: 554 KEKEESIRIREEARQERETTELV-----NAEIKAEK-------ERLN---QRQEEM---L 595
Query: 812 SKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMAN 633
+ R + KEE + D+ + ++E ++ + E E K E Q+
Sbjct: 596 RERQEIERIKHETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKE 655
Query: 632 KLE----EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK 510
++E E+++ D+ + L+ E R++ EM+
Sbjct: 656 QMEEAKVELEEEREDLERKRDLVSREIEQAEFLRNEILRVKEEME 700
Score = 75.1 bits (183), Expect = 1e-10
Identities = 143/796 (17%), Positives = 329/796 (41%), Gaps = 40/796 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNL--LEQKDNIIVELSHKLQEN 2127
E+ R+ E ++ T +Q + ++ D+ K N + L Q+ +++ +
Sbjct: 7864 ELERIKTESQRATEHMQSH---AEERAGDLGEKEPVNTRIQRLIQEAEKASKMAWSTKHE 7920
Query: 2126 EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL 1947
E R +Q ++ SVE+ ER++++ + + ++ H +E L D+ K+
Sbjct: 7921 PEMR--MQREV-SVEE----ESVERQDMSANMQRMILEIEHARETLRGMKDEVQAARKER 7973
Query: 1946 QDLENQK-ETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQN----KQLELE 1782
+LEN K E ++ + + + EQ+ + + EK++ +++L+ E+N + +LE
Sbjct: 7974 SELENMKLEFLTMKKNMEKTYEQQ---NDEIQKEKQQIESSKMLLSRERNDLEQNRADLE 8030
Query: 1781 IEKLYGSLQMKQM--ENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELA 1608
+K +L +++ EN LL+ + + + L + E ++ Q + E
Sbjct: 8031 RQKQIMALDKQKLLAENELLEREKADVIKIIENLESLREEATRERATETAQATRRDSEEL 8090
Query: 1607 RTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQV 1428
K S D ++ + + ++ ++ L+ +K D+ + E+ L+ QM +
Sbjct: 8091 MQKMEALSMEDFQEASKNQMVELKRQIDKLIELKADLLQQQTELKKTKADLKQ--QMDDL 8148
Query: 1427 ALEQMQDTKSELFAEAEIRAQEVLRLQAEVD----AIQHILIELKRKNQTLQDESQRNAK 1260
+ + K E +++ R E++ +Q + D IQ + +E KR + L+ E K
Sbjct: 8149 EKTRSEILKHEKDTDSKTRELELIEIQRQKDDLETRIQKLTLE-KRDLEVLRSEIVLEKK 8207
Query: 1259 ELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVEN 1080
+L ++ + + S + E++ + Q+ ++ + +L N
Sbjct: 8208 DLDQKMKQVIRKRDEMEKIRSDIANATEEINRERQELEILRNNVQSARHDFELLLERTAN 8267
Query: 1079 LKSELKESKDLEGYFLRLFEIL---------LGQHVEVASLDIESCRFAEEKLMRILDEL 927
L+ E + D+E L + +I + + +E + ++I+ + ++ R + ++
Sbjct: 8268 LEDEESAATDIERLVLEVVKIREMVRNLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDI 8327
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRA---------EAMSVLISKSLGNGRANQRE 774
+R L E E +++ + RA E+M ++ K + E
Sbjct: 8328 GQIRENLGGLGEE--IEKTRRDKRELEKMRAELAEKQQEQESMREMLHKEREELEQLKDE 8385
Query: 773 FQNKEED----SSGVDLLKNKCTRLEF-QVQKLSEK----AEMFETKSREAQQMANKLEE 621
++ED V+ + +K EF +QK E+ E TK R+ Q+ + +++
Sbjct: 8386 INREKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNSDVQD 8445
Query: 620 MQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIG 441
++QT+ ++ + K+ +L + K EL +E +I E I
Sbjct: 8446 LRQTIEEINIQHGKKRAELEGIGFELKKGEQLLEKQKDEL--------KENGWIVE-EIK 8496
Query: 440 DEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSV 261
++ D+ ++ +D + ++ MD R S +Q + L+ S+
Sbjct: 8497 NKKDS--LEKINMEILRKNEDMDKEKGKLRQEKQEMDLFR------SELQRQREDLETSI 8548
Query: 260 QELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAW 81
Q+L + + I + K+L+ + Q++ ++ K F
Sbjct: 8549 QKLTHEKREME------------VLRSEIVLEKKDLDQKMKQVIRKRDEME---KIRFDI 8593
Query: 80 ANSMHDLNGQEQKLKV 33
AN+ +++G+ Q+L++
Sbjct: 8594 ANARVEIDGERQELEI 8609
Score = 75.1 bits (183), Expect = 1e-10
Identities = 126/646 (19%), Positives = 248/646 (38%), Gaps = 31/646 (4%)
Frame = -1
Query: 2279 EEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQN 2100
EEK +L + + E I K + +EQ EL ++Q E+Q +Q+
Sbjct: 9565 EEKNEMADLSRELQKAKDELEKIAYKTNKERHEVEQMQ---AELHSQIQAIEQQGQIMQD 9621
Query: 2099 DMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKET 1920
+E+ Q + EE+ + + HL L + +E D+E K+
Sbjct: 9622 KQNHLEEKELSIQRKEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQK 9681
Query: 1919 VSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQME 1740
+K+ L +L ++ L E K+ + +Q ++ ++ + +EK+ LQ
Sbjct: 9682 NNKDFELLEKIRSELENEKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQ----- 9736
Query: 1739 NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDIN-IEDELARTKEVGRSATDMKKV 1563
S+ Q ++E K D+N + E+ R K+V D K+
Sbjct: 9737 ---------------------SKREQTEKE---KADLNRVNAEIQREKQV----IDKKRH 9768
Query: 1562 NSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAE 1383
++ +E L +K ++ +E++ L + +VQ+ E + E+ +
Sbjct: 9769 MTNRA------MEELETIKTELKERQEKIQTEQEKLEEEKLLVQIEAENLNKVLEEIKRQ 9822
Query: 1382 AEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRN----------AKELWNAKARL 1233
E L+ + ++ E +RK ++++ Q N K++ K L
Sbjct: 9823 QEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQKQEL 9882
Query: 1232 N--------NVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEH---------- 1107
+++ N+E RSL E L QKA +I +R+ +E E
Sbjct: 9883 QKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNKL 9942
Query: 1106 NVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL 927
+VL +E++N ++E K +++ R K + L+E
Sbjct: 9943 DVLQNEMQNENKAMEEIK----------------------YELDGKRNEINKEQQRLEES 9980
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSS 747
+ NE K + DYE++ + E M V + + + KE D
Sbjct: 9981 LRAINEE---KGDLEIMRADYEKQE---QQIEEMRV------------EAKMERKELDQI 10022
Query: 746 GVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXX 567
+L K+K T ++++ +KL+ M E + + ++M ++L +Q + D
Sbjct: 10023 KSELEKDK-TEIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKE 10081
Query: 566 XIRVRSLKKENTRLRSEMKGELTPSRS-FK-HREGSFIKEINIGDE 435
+ ++N + + E+ R+ FK +E ++ NI DE
Sbjct: 10082 ANTEKDKIEKNKEIVERLMAEVEEQRNDFKLKKEELALERQNIVDE 10127
Score = 75.1 bits (183), Expect = 1e-10
Identities = 118/636 (18%), Positives = 280/636 (44%), Gaps = 27/636 (4%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLE-QKDNIIVELSHKLQEN 2127
KE S L + +Q +E + + ++ E + ++E + ++ QK+ + +E E
Sbjct: 10361 KERSELDNKIQQTDLE-KHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDIERQKIADEQ 10419
Query: 2126 E---EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFME 1956
+ + +S LQN+ + + ++ V + ERE L KE + ++ M+
Sbjct: 10420 DLLIQNKSELQNENERIRNINEVIKKERETL--------------KEMEAHLEKEKEEMK 10465
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIE 1776
++ QKE + K + Q L L +++E ++ ++ + + ++
Sbjct: 10466 SITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQVS 10525
Query: 1775 K-----LYGSLQMKQMENTLLKDGNEKIYDL---CKLLATKSREVQGQQEGILKQDINIE 1620
K L +MK+ E L++ +I ++ +L K + + ++E ++ + ++
Sbjct: 10526 KQKEEDLTKQKEMKE-ERKSLEETKARIIEMKTKAELEDIKKEKEKEEEEEEMRVKVEMD 10584
Query: 1619 DELARTKEVGRSATDMKKVNSDAG---AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRN 1449
KE+ R +++K+ S+ K++ +++ K ++ +K E++ +
Sbjct: 10585 G-----KELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKSEIMKQRQQMEE 10639
Query: 1448 DAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQ- 1272
+ ++ ++Q K ++ EI + ++ ++ + IQ EL + Q + DE
Sbjct: 10640 ERSELENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDL 10699
Query: 1271 --RNAKELWNAKARLNNVMSKNINLESQNRSLK-AELHLQAQKAFQIQEERNVVESEHNV 1101
+N EL N R+ N+ N ++ + +LK E HL+ +K EE V E
Sbjct: 10700 LIQNKSELQNENERIRNL---NEIIKKERETLKEMEAHLEKKK-----EEIKSVSEETRR 10751
Query: 1100 LSSEVENLKSEL-KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL- 927
L ++E + +++ K++KD L+ Q ++ + E ++L + +DE
Sbjct: 10752 LKEDLEKMSTDVNKQNKD-----------LMNQR-DLLEQEREEINHKWKQLQQRIDEFD 10799
Query: 926 --ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEED 753
+ + E K + + E +RK++ ++A + + +K+ ++E +N+EE+
Sbjct: 10800 AQVSKQKEQDLPKEKGMKE----DRKSLEETKANVIE-MKTKAEPEEIKKEKEKENEEEE 10854
Query: 752 SSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXX 573
E +V +E+ E+++ KS E +++ ++++ Q+ L+D
Sbjct: 10855 EE----------EEEIRVIVETERKELYQIKS-ELERVRSEIDHEQKKLNDYMKMIEQEK 10903
Query: 572 XXXIRVRS-LKKENTRL---RSEMKGELTPSRSFKH 477
+++S + K+ ++ RSE+ ++ + KH
Sbjct: 10904 EDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKH 10939
Score = 74.3 bits (181), Expect = 2e-10
Identities = 113/597 (18%), Positives = 256/597 (42%), Gaps = 32/597 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNL------LEQKDNIIVELSHK 2139
E RL + +++ E QE R K+E + K E N+ E+ + + E+ +
Sbjct: 583 EKERLNQRQEEMLRERQE---IERIKHETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQ 639
Query: 2138 LQENEEQRSALQNDMQSVEQMHAVSQTEREELNR----------QLVLLRDDVNHLKEAL 1989
+++ E++ +Q + +E+ + ERE+L R Q LR+++ +KE +
Sbjct: 640 IEDIEKKVEEIQKTKEQMEEAKVELEEEREDLERKRDLVSREIEQAEFLRNEILRVKEEM 699
Query: 1988 SMA--------VDDRAFMEKQLQDLEN-QKETVSKELALSVSREQKLA--SDLKALSEKE 1842
V+ RA + +L+ LE ++ET + + S+ + + L L +
Sbjct: 700 ESRWRETETEEVELRAKTQHELERLEKLREETERSQKNIEESKIELMLWKESLDKLKGEM 759
Query: 1841 ESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQ 1662
E K+ +++Q + K E ++ + L++++ E T+ ++ ++ D + + +
Sbjct: 760 EEDKHVVIMQMNEAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQH 819
Query: 1661 GQQEGILKQDINIEDELARTKEVGRSATDM--KKVNSDAGAKVSGILEMLLPMKDDVFSL 1488
+ E + +N E E A ++ +M KK ++ + ++ L +D++
Sbjct: 820 AEMEDWFRV-VNKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKK 878
Query: 1487 KEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIEL 1308
EE + + + Q + LE+M+ + E + ++ + + V+ ++ L++
Sbjct: 879 AEE----LEQINKEIQRARQELEKMRYFEKESLQKM---LEDTQQERVFVEQVRSELLKN 931
Query: 1307 KRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEER 1128
K E KEL + ++ N + +LE + + + +++ Q+Q ++
Sbjct: 932 KADQDKCLFEMDSERKELEQMRFQVEN---EKKDLEQRRYEM---MRYDVEQSAQVQRQK 985
Query: 1127 NVVESEHNVLSSEVENL-KSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEK 951
+E + L + E++ +S +D E L + EI + E + +E + EE
Sbjct: 986 EELEKIKSQLVIDTESMNRSRELARQDREKAELLIVEIQ--EQREDVNKRLEETKQREEA 1043
Query: 950 LMRILDELICLRNENAKLKNEALYEYHDYE--RKNVSGSRAEAMSVLISKSLGNGRANQR 777
L + ++ R + K++ E L YE ++ ++ RAE + G+ ++
Sbjct: 1044 LRLLRKDMENEREDLEKIRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREK 1103
Query: 776 EFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTL 606
KEE ++ +K + +E +L+++ E + K A+ LE M+ L
Sbjct: 1104 INHEKEEMIRKMEAMKREMGEIEDMKVELTKQKENIDMKMEHARLEMTNLEMMKADL 1160
Score = 71.6 bits (174), Expect = 1e-09
Identities = 115/638 (18%), Positives = 266/638 (41%), Gaps = 70/638 (10%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDI-----------CLKIEANNNL------LE 2175
+E++ L EE K+ + E++ +R++ E I + N N+ ++
Sbjct: 6778 EEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQ 6837
Query: 2174 QKDNIIVELSHKLQEN----EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVN 2007
QK N + ++S ++ + E+++ +Q + +E+MH Q ++E + L + D+
Sbjct: 6838 QKRNALEKMSKEISRDRMKLEDEKKEIQLAREELERMHGDMQRQQEAKDHLLSGITDESL 6897
Query: 2006 HLKEALSMAVD----DRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKA------ 1857
K + + D+A ++ + ++ K+ V + + + L D ++
Sbjct: 6898 LKKSEAEIVLQPSQVDKAKPARKTEISDSDKQPVFVQQMPEMDLKDALKKDFESEKLDLP 6957
Query: 1856 -----LSEKEESTKNQLLIQTEQNK--QLELEIEKLYGSLQMKQMENTLLKDGNEKIYDL 1698
L + ++ Q LI+ E +K Q+ E++K ++ K+ + +++ +K+ D+
Sbjct: 6958 KVKDVLPQDQQMKLEQKLIEDEMDKLKQMRAELQKEADQIEKKKQD---MQNERQKLDDM 7014
Query: 1697 CKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEML 1518
L + R + E I Q +N + + + TD +++ ++ + +
Sbjct: 7015 AARLQEERRTNERLNEEINIQKVNQQKQATAFQ---MEKTDFERIKTEIDQANKELADQQ 7071
Query: 1517 LPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEV 1338
K + +++E N ++ V+ + + S A+++ +++L+ Q E+
Sbjct: 7072 EKNKKTITEMQKERETLEEMRANISKQVETITNENKSLSSRESELAKLQ-EDILQQQQEM 7130
Query: 1337 DAIQH-ILIELKRKNQT----------LQDESQRNAKELWNAKARLNNVMSKNINLESQN 1191
D +++ I++E+ + +Q + D E+ N + V+++ N++S
Sbjct: 7131 DELKNTIMMEMCQLDQRQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQTRNIKSDM 7190
Query: 1190 RSLKAELHLQAQKAFQIQEERNVVESEHNVLSS--------------EVENLKSELK--- 1062
SLK E Q ++ EE++++E E +L+ E+ENLK E +
Sbjct: 7191 VSLKMEKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIK 7250
Query: 1061 -ESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL-ICLRNENAKLKNE 888
E K+LE + L +G E + + EE + +L I R K E
Sbjct: 7251 NEKKELEKMKISLQRKAIG-FKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEE 7309
Query: 887 ALYEYHDYERKN-VSGSRAEAMSVLISKSLGNGRANQRE-FQNKEEDSSGVDLLKNKCTR 714
L + RK + + + K+ ++ E ++ + E + + LK T
Sbjct: 7310 RLDQTEKKRRKTYYTEDLFQEEKTDLQKTKEEINYDREEIYRQRTELNKEKETLKQMHTS 7369
Query: 713 LEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSD 600
+++ + ++ E + E Q+ +L+ Q+ + D
Sbjct: 7370 NLKEIENIEKEKEKIQRTWNELDQIRAELQNKQRDMDD 7407
Score = 70.9 bits (172), Expect = 2e-09
Identities = 128/646 (19%), Positives = 260/646 (40%), Gaps = 99/646 (15%)
Frame = -1
Query: 2258 ELQENFNALRQ-----KNEDICLKIEANNNLLEQKD--NIIVELSHKLQENEEQRSALQN 2100
ELQ +R KNE LK + ++K+ +II E S + ++ E+ + +
Sbjct: 10137 ELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNV 10196
Query: 2099 DMQSVEQMHAVSQTEREELNRQLVLLRDDVNH-------------------------LKE 1995
Q ++ + EREE+N + + ++ L+E
Sbjct: 10197 QKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEE 10256
Query: 1994 ALSMAVDDRAFME-------KQLQDLENQKETVSKE--------LALSVSRE-------- 1884
++ + E +++++L+ +E + KE + L + RE
Sbjct: 10257 VNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSE 10316
Query: 1883 ------------QKLASDLKAL-SEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQM 1743
+KL D+K + EKE+ K + I T Q +++E E +L +Q +
Sbjct: 10317 LVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMT-QKQEMEKERSELDNKIQQTDL 10375
Query: 1742 ENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDE----LARTKEVGRSATD 1575
E ++ E + L + + E+Q Q+E + + I DE + E+
Sbjct: 10376 EKHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDIERQKIADEQDLLIQNKSELQNENER 10435
Query: 1574 MKKVNSDAGAKVSGILEM---LLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDT 1404
++ +N + + EM L K+++ S+ EE L + ++ + +
Sbjct: 10436 IRNINEVIKKERETLKEMEAHLEKEKEEMKSITEETRRQKEDLEKMSTDIKEQNQDLMKQ 10495
Query: 1403 KSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNV 1224
+ L E E E +LQ +D + + K ++ T Q E + K L KAR+ +
Sbjct: 10496 RDLLEQEKEDINHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEM 10555
Query: 1223 MSK----NINLESQNRSLKAELHLQAQK--------AFQIQEERNVVESEHNVLSSE--- 1089
+K +I E + + E+ ++ + +++ ER+ ++ E L+ +
Sbjct: 10556 KTKAELEDIKKEKEKEEEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKI 10615
Query: 1088 -------VENLKSE-LKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILD 933
+E +KSE +K+ + +E L + ++E DIE+ + +KLM ++
Sbjct: 10616 IEQEKQNLEKMKSEIMKQRQQMEEERSELENKIKQTYIE--KCDIENSKEIVQKLMVEVE 10673
Query: 932 ELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEED 753
E + + + E L D ER+ + A+ +LI N+ E QN+ E
Sbjct: 10674 E----QKHEIQFQKEEL----DIERQKI----ADEQDLLIQ--------NKSELQNENER 10713
Query: 752 SSGV-DLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEM 618
+ +++K + L+ L +K E ++ S E +++ LE+M
Sbjct: 10714 IRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRLKEDLEKM 10759
Score = 70.1 bits (170), Expect = 4e-09
Identities = 121/594 (20%), Positives = 247/594 (41%), Gaps = 45/594 (7%)
Frame = -1
Query: 2258 ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQ 2079
+++EN L ++ IE + + + EL+ K QE E R L + + +EQ
Sbjct: 8329 QIRENLGGLGEE-------IEKTRRDKRELEKMRAELAEKQQEQESMREMLHKEREELEQ 8381
Query: 2078 MHAVSQTERE--ELNRQLV----------------LLRDDVNHLKEALSMAVDDRAFMEK 1953
+ E+E E+ R+LV ++++ + E L D +
Sbjct: 8382 LKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNS 8441
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEK 1773
+QDL E ++ + + + + +LK + E K++L ++N + EI+
Sbjct: 8442 DVQDLRQTIEEINIQHGKKRAELEGIGFELKKGEQLLEKQKDEL----KENGWIVEEIKN 8497
Query: 1772 LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSR------EVQGQQEGILKQDINIEDEL 1611
SL+ ME +L+ + + KL K E+Q Q+E L+ I
Sbjct: 8498 KKDSLEKINME--ILRKNEDMDKEKGKLRQEKQEMDLFRSELQRQRED-LETSIQKLTHE 8554
Query: 1610 ARTKEVGRSATDMKKVNSDAGAK-VSGILEMLLPMKDDVFSLKEEVLG---NINSLRNDA 1443
R EV RS ++K + D K V + + ++ D+ + + E+ G + LR++
Sbjct: 8555 KREMEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRFDIANARVEIDGERQELEILRDNV 8614
Query: 1442 QMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNA 1263
Q + E++ + + L E E A ++ RL EV I+ ++ LK + + +ES+
Sbjct: 8615 QSARQDFERLVERTANLEVE-ESAATDIERLVLEVVKIREMVRNLKGEMERRMEESKVEI 8673
Query: 1262 KELWNAKARLNNVMSKNINLESQNRSLKAEL--------HLQAQKAFQIQEERNVVESEH 1107
E K+ + ++ + LK E+ +L+ KA +++E++ ES
Sbjct: 8674 DEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKA-ELEEKQQEEESMR 8732
Query: 1106 NVL---SSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRIL 936
+L E+E LK ++ K+ L E + + D++ + E+L +
Sbjct: 8733 EILQKEKEELEQLKKDINREKEDIEISRELVESEIYEGEVKGFTDVQKYK---EELQIVT 8789
Query: 935 DELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEE 756
+EL+ + +L ++ + E ++ + +A I+ + R E Q K+
Sbjct: 8790 EELLTKKRNLEQLNSDVQHLMQTLEEVDIQYIKKKAELEHITSEI-QKREQILEKQKKKL 8848
Query: 755 DSSG-----VDLLKNKCTRLEFQV-QKLSEKAEMFETKSREAQQMANKLEEMQQ 612
+ +G ++++K + ++ QK + + E RE Q+ E+Q+
Sbjct: 8849 EENGWIIEEIEMMKVTLESINMEILQKREDMEKEKENLRREKQETELFRGELQR 8902
Score = 69.3 bits (168), Expect = 7e-09
Identities = 125/585 (21%), Positives = 244/585 (41%), Gaps = 25/585 (4%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEE 2121
EVS E K EL E R++ +D+ +++E N ++ E+ + EN +
Sbjct: 13713 EVSLKQHELKNKETELDEQ----RKEMDDLRMQLEMRQNSTNKQQQ---EVDVFIVENMK 13765
Query: 2120 QRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQD 1941
R ND++S M + ER +L + D N L + + AV +EK D
Sbjct: 13766 MR----NDLES---MKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTD 13818
Query: 1940 LENQKETVSKEL-ALSVSREQ--KLASDLKALSEKEESTKNQLLIQTEQNKQLE-LEIEK 1773
++ +KE V KE + V ++ K +L++L+ + E K ++ + Q + LE L +
Sbjct: 13819 IKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADL 13878
Query: 1772 LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEV 1593
L G+ +K + T + E K EV+ Q L++ N +EL T E
Sbjct: 13879 LAGADDIKTLVQTEKQMAIED--------TEKKTEVELQMN--LQKQKNELEELRNTIEA 13928
Query: 1592 GRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRND-AQMVQVALEQ 1416
+ + +K+ D K + ++ + DV ++ L ++ + N+ Q Q LE+
Sbjct: 13929 EKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELER 13988
Query: 1415 MQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKAR 1236
+ L+ E D I++ ++ + Q++ +R EL K
Sbjct: 13989 L--------------------LEKERDDIENCKKIIESEKQSI----ERERAELKRLKEE 14024
Query: 1235 LNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVE------SEHNVLSSEVENLK 1074
+ + + + +N K + HL+ +KA +E N+ E SE ++L+ E+E +
Sbjct: 14025 VEVQHERTLLQQDKNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKR 14084
Query: 1073 SE-----LKESKDLEGYFLRLFEILLGQHVEVASLDIE-------SCRFAEEKLMRILDE 930
E L E ++E + + ++L + ++ D + R AE + LDE
Sbjct: 14085 QEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTS--LDE 14142
Query: 929 LICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKE--E 756
+ + + + AL E V+ + + + + + +L + R+ N E E
Sbjct: 14143 I----TKTDERRQRALEE-------TVATTAKQPIVIKLEDTLTSEVQEMRDHLNNEIKE 14191
Query: 755 DSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEE 621
+ ++K + +L+ + + E FE EA + ++ EE
Sbjct: 14192 LARMKTIMKMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNEE 14236
Score = 69.3 bits (168), Expect = 7e-09
Identities = 86/415 (20%), Positives = 173/415 (41%), Gaps = 36/415 (8%)
Frame = -1
Query: 2180 LEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHL 2001
++Q H +++EE+ SA + +V ++ +E +E+ L +DV +
Sbjct: 14820 IQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVARM 14879
Query: 2000 KEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQL 1821
K + M D +E+ D++ Q E + + ++ + + L L+ +E N L
Sbjct: 14880 KTIMKMEKDQ---LEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTL 14936
Query: 1820 LIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKI-YDLCKLLAT-KSREVQ----- 1662
++NK++E E + + L+K E I +L +L T + RE+Q
Sbjct: 14937 ---DKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQEREIQRGTDD 14993
Query: 1661 -GQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDA-GAKVSGILEM---------LL 1515
+ + + + EL KE + D +DA AK G E +L
Sbjct: 14994 TSNEREKYDEKVTYKTELEDNKEKKKPDRDSSLKLTDADSAKTDGEREAQTLETKVQDVL 15053
Query: 1514 PMKDDVFSLKEE----------VLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQ 1365
+ DD +EE ++ +N + D Q ++ ++ KS + E R
Sbjct: 15054 QLTDDTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEKCRSAEEEKSVIMESLERRRN 15113
Query: 1364 EVLRLQAEV----DAIQHILIELKRKNQTLQDESQRNAKEL---WNAKARLNNVMSKNIN 1206
+ ++Q+EV I+H L ++K + Q ++ + QR + + W ++ +
Sbjct: 15114 SLEKVQSEVLTLTQEIEH-LAQIKTEMQQIETKMQRQTRSVATQWETDVQIQQEGQEATE 15172
Query: 1205 LESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-KESKDLE 1044
+ + K+E + A+K ++ V + L+SEV+ ++ L KE +D+E
Sbjct: 15173 TRG-HITKKSEEEISAKKT-----KQPTVTKLEDTLTSEVQEMRDSLNKEMEDVE 15221
Score = 68.9 bits (167), Expect = 9e-09
Identities = 119/605 (19%), Positives = 261/605 (43%), Gaps = 46/605 (7%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQ 2103
E E + +E Q++ + + E+ ++ + + + N +L +LQ +EQ +
Sbjct: 9177 ELENRVFMEEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQREKEQLEISK 9236
Query: 2102 NDMQSVEQMHAVSQTEREELNRQLVLLR-------DDVNHLKEALSMAVDDRAFMEKQLQ 1944
N +EQ Q + L RQL LR D+ N L++ S + + + + K+ +
Sbjct: 9237 NQ---IEQEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKERE 9293
Query: 1943 DLEN-------QKETVSKEL-ALSVSREQ--KLASDLKALSEKEESTKNQLLIQTEQNKQ 1794
DLEN +K+ + +E L + RE+ K+ S+L+ E ES + ++ + E+ Q
Sbjct: 9294 DLENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINNKMEELLQ 9353
Query: 1793 LEL-------EIEKLYGSLQ--MKQMENTL--LKDGNEKIYDLCKL-LATKSREVQGQQE 1650
+++ EIEK LQ +EN ++ +K D+ + + K RE++ Q +
Sbjct: 9354 MKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQLD 9413
Query: 1649 GILKQDINIEDEL-ARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVL 1473
K+ + +E+ + K++ DMK+ + G+LE K ++ K+E+
Sbjct: 9414 ---KETKRLSEEIELKVKDLEMEMADMKRQKQEI-EDTKGLLE---KEKQELKQEKKELE 9466
Query: 1472 GNINSLRNDAQMVQVALEQMQDTKS---ELFAEAEIRAQEVLRLQAEVDAIQHILIELKR 1302
+ L + Q + + K+ +L E EI +++ ++ ++ +Q + + +R
Sbjct: 9467 DQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQR 9526
Query: 1301 KNQTLQDESQRNAKELWNAKARLNN-----VMSKNINLESQNRSLKAELHLQAQK----- 1152
N ++E+++ + L + +S +E +N LQ K
Sbjct: 9527 LNDQTREENKKEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDELEK 9586
Query: 1151 -AFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIE 975
A++ +ER+ VE L S+++ ++ + + +D + + L E+ + + E +
Sbjct: 9587 IAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQDKQNH-LEEKELSIQRKEEEIKIGNT 9645
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGN 795
+ +E L +L+ E K +++ D E ++ + I L N
Sbjct: 9646 EFQIEQEHLNNVLE-------ETNKRQHDLEVMRADIELNKQKNNKDFELLEKIRSELEN 9698
Query: 794 GRANQREFQNKEEDSSGVDL--LKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEE 621
+ + + + +++ V L L+ + RLE +L K E E + + ++ +++
Sbjct: 9699 EKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQTEKEKADLNRVNAEIQR 9758
Query: 620 MQQTL 606
+Q +
Sbjct: 9759 EKQVI 9763
Score = 68.6 bits (166), Expect = 1e-08
Identities = 116/606 (19%), Positives = 255/606 (42%), Gaps = 39/606 (6%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQK-NEDICLK----------IEANNNLLEQKDNII 2157
+ + +L +E ++ ++ E N RQ+ E+I LK I+ L II
Sbjct: 7438 ENIQKLMKELQEERLKTSEALNKERQQFTEEIKLKNDSLDEIQAEIDRQKRALVTDKEII 7497
Query: 2156 VELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAV 1977
+ LQ+ ++ R Q+D + + + Q ERE L++ V + L+ +
Sbjct: 7498 TKQMMDLQKTQDVRR--QSDESDIARANL--QRERESLDQLSVEILKQKQDLERERDELL 7553
Query: 1976 DDRAFMEKQLQDLENQKETVSKELALSVSREQ---KLASDLKALSEKE---ESTKNQLLI 1815
+ +E Q D EN K+ ++ L S E+ +L D + E + +L +
Sbjct: 7554 EQWRLVETQKMDNENVKQLKTELLDEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNL 7613
Query: 1814 QTEQNKQLELEIEKLYGSLQMK------QMENTLLK-----DGNEKIYDLCKLLATKSRE 1668
Q + + ++E++ G LQMK +M+ L + + + Y + L + E
Sbjct: 7614 QKQGIQDERAQLERMKGELQMKADDIERKMQEILYEKQKYAERKSENYKIQTYLDEANAE 7673
Query: 1667 VQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKV---SGILEMLLPMKDDV 1497
VQ + + + D N+E E+ ++ + ++V GAK+ I + L +D +
Sbjct: 7674 VQKLNKELERYDENLE---KCKLELDKARAETERVKQ--GAKIPETQQIEQSLQKERDYI 7728
Query: 1496 FSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHIL 1317
++ + ++ D +++ +++ ++++ + E ++ + + E IQ
Sbjct: 7729 EDIRRNLFKKEEAIEKDKAEIRLRHQELDLIQAKVVKQKEEMVKQKIESERE---IQQEK 7785
Query: 1316 IELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQ 1137
+L+R + L+D+ Q+ +E+ K + K +++++ R + A+K +++
Sbjct: 7786 KKLQRSEEELEDKMQKIKREMIELKLLQDETDGKRKDVDNKMRQV-------ARKRDELE 7838
Query: 1136 EERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAE 957
+ + VES L + L +E E + ++ R E + H E + D+
Sbjct: 7839 KMKADVESASKKLEVDRVMLNTERDELERIKTESQRATE-HMQSHAEERAGDLGEKEPVN 7897
Query: 956 EKLMRILDEL--------ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSL 801
++ R++ E +++ E E ER+++S + + M + I +
Sbjct: 7898 TRIQRLIQEAEKASKMAWSTKHEPEMRMQREVSVEEESVERQDMS-ANMQRMILEIEHAR 7956
Query: 800 GNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEE 621
R + E Q ++ S ++ +K LEF K + +E ++ E Q+ ++E
Sbjct: 7957 ETLRGMKDEVQAARKERSELENMK-----LEFLTMK-KNMEKTYEQQNDEIQKEKQQIES 8010
Query: 620 MQQTLS 603
+ LS
Sbjct: 8011 SKMLLS 8016
Score = 65.5 bits (158), Expect = 1e-07
Identities = 110/608 (18%), Positives = 255/608 (41%), Gaps = 40/608 (6%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIE--LQENFNALRQKNEDICLKIEANNNLLEQKDNI-----IVELSH 2142
E+ +L + E++ I+ + N +E + K E ++ ++K + + +
Sbjct: 14631 ELLQLKQTEQEREIQRGTDDTSNERENYDEKVTYKTELEDSKEKKKPDRDSSLKLTDADS 14690
Query: 2141 KLQENEEQRSALQNDMQSVEQMHAVSQTEREEL-----NRQLVLL-----RDDVNHLKEA 1992
+ E + L+ +Q V Q+ + ++EEL N+ ++L + D+ LKE
Sbjct: 14691 AKTDGEREAQTLETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEE 14750
Query: 1991 LSMAVDDRAFMEKQLQDLENQKETVSKELALSVSRE----QKLASDLKALSEKEESTKNQ 1824
A ++++ + + L+ N E V E+ LS+++E ++ ++++ + K +
Sbjct: 14751 CRSAEEEKSVIMESLERRRNSLEKVQSEV-LSLTQEIDHLAQIKTEMQQIEIKMQIQTRS 14809
Query: 1823 LLIQTEQNKQLEL--EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQE 1650
+ Q E + Q++ E + G + K E K + + KL T + EVQ ++
Sbjct: 14810 VATQWETDVQIQQGQEATETTGHITKKSEEEISAKKTKQPT--VTKLEDTLTSEVQEMRD 14867
Query: 1649 GILKQDINIEDELARTKEVGRSATD-MKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVL 1473
+ K+ +++AR K + + D +++ SD ++ + ++ +E++L
Sbjct: 14868 SLNKE----MEDVARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLL 14923
Query: 1472 G---NINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKR 1302
+ L N +E +T + A+ E ++ ++ + + I++ L++LK+
Sbjct: 14924 QLTHDKEDLSNTLDKKNKEIENNTETSLKKIAQLETT---IVLMKKDKENIENELLQLKQ 14980
Query: 1301 KNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNV 1122
Q + E QR + N + + + ++ LE K + + K +
Sbjct: 14981 TEQ--EREIQRGTDDTSNEREKYDEKVTYKTELEDNKEKKKPDRD-SSLKLTDADSAKTD 15037
Query: 1121 VESEHNVLSSEVENL----KSELKESKDLEGYFLRLFEILLGQHVEVASLDI----ESCR 966
E E L ++V+++ ++ ++L +I+L + A D+ E CR
Sbjct: 15038 GEREAQTLETKVQDVLQLTDDTTQDQEELHDEMENKMKIIL--ELNEAKKDLQKLKEKCR 15095
Query: 965 FAEEKLMRILDELICLRNENAKLKNEAL---YEYHDYERKNVSGSRAEAMSVLISKSLGN 795
AEE+ I++ L RN K+++E L E + + E ++S+
Sbjct: 15096 SAEEEKSVIMESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIETKMQRQTRSVAT 15155
Query: 794 GRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEK--AEMFETKSREAQQMANKLEE 621
+ Q + ++++ K + E +K + ++ +T + E Q+M + L +
Sbjct: 15156 QWETDVQIQQEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNK 15215
Query: 620 MQQTLSDM 597
+ + M
Sbjct: 15216 EMEDVERM 15223
Score = 63.2 bits (152), Expect = 5e-07
Identities = 127/614 (20%), Positives = 263/614 (42%), Gaps = 70/614 (11%)
Frame = -1
Query: 2231 RQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTER 2052
R + ++ I+ LE II++ H+L + +E A++ND + E+M + + E+
Sbjct: 1518 RASDLELSASIQKERQELEHYKEIILKEKHELNKIKEDVKAVKNDAE--ERMIKLHEEEK 1575
Query: 2051 EELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLA 1872
E +++ L E+QLQ +KE K L + Q+L
Sbjct: 1576 EMKTKRVSLQN-------------------WERQLQ---TEKEKNQKGLDAIWNENQQLN 1613
Query: 1871 SDLKALSEKEESTKNQLLIQTEQNK---QLELEIEKLYGSLQMKQMENTLLKDGNEKIYD 1701
+ L KE L +Q+E++K + LEI+++ +Q + ME+ D I +
Sbjct: 1614 ERKQQLDIKE------LHLQSEKSKLEYKKPLEIKQVDAQVQTELMEDASEYDMALSIEE 1667
Query: 1700 LCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEM 1521
L K + + ++ ++ +L Q +E ++A E+ R +++ + + +E+
Sbjct: 1668 LDK----QRQFLEYFKQELLAQKCTMERQMAEI-ELSRDELSLREATLQTATQTTADMEL 1722
Query: 1520 LLPM--------KDDVFSLKEEV-------LGNINSLRNDAQMVQVALEQMQDTKSELFA 1386
L + KD++ K EV I R +MV++ LE+ +D + +
Sbjct: 1723 QLELQKQELEQTKDEMERTKLEVQKGWVDLQTQIAESREKEEMVRIELEKARDVLNRIRQ 1782
Query: 1385 EAEIRAQEV-----LRLQAE---VDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLN 1230
+ E Q + L E ++A + ++ + KR + ++ E QR + + +K +
Sbjct: 1783 DVETEKQTMEADLKFTLAKEFENLEAQRKMMEDEKRALENMKYELQRESGYIERSK---H 1839
Query: 1229 NVMSKNINLESQNRSLK---AELHLQAQKAFQIQEER------------------NVVES 1113
N+ + N+E+ LK EL + Q+Q ER N +++
Sbjct: 1840 NMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERSREIKDLENLRELNELTLNQIKT 1899
Query: 1112 EHNVL----------SSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRF 963
+ +VL E+EN KS++K + Y L+ + L + + DI++ F
Sbjct: 1900 KSDVLEKISELNSQQKDEIENEKSKIK----IREYDLQQMQTDLNRQ-QKEMQDIQNAVF 1954
Query: 962 AEE-KLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRA----------EAMSVL 816
E+ +L + DE+ E K + + ++ E+ N+ RA M+ L
Sbjct: 1955 MEKSELKKSQDEIA----EQLKQVGD-MMQFTQNEKDNLDRERAAIIEQKLQMERDMTHL 2009
Query: 815 ISKSLGNGRANQREFQNKEE--DSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQ 642
+++ L + + ++E N++ + + L+++ + ++ EK EM + + + +
Sbjct: 2010 LNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEM-QLQRQSIAE 2068
Query: 641 MANKLEEMQQTLSD 600
+KLE + QTL++
Sbjct: 2069 EKDKLESVLQTLAE 2082
Score = 63.2 bits (152), Expect = 5e-07
Identities = 119/611 (19%), Positives = 253/611 (41%), Gaps = 43/611 (7%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQ---- 2133
E+ +L + E++ E+Q + + E K+ L + K+ I + L+
Sbjct: 14290 ELLQLKQIEQER--EIQRKADVTSTEKEMYTEKVTYKTELEDSKEKIKPDRDSTLELTDT 14347
Query: 2132 -----ENEEQRSALQNDMQSVEQMHAVSQTEREEL-----NRQLVLL-----RDDVNHLK 1998
+ E + L+ +Q V Q+ + ++EEL N+ ++L + D+ LK
Sbjct: 14348 DSAKTDGEREAQTLETKVQDVLQLTDDTTQDQEELHDEMENKMKIILELNKAKKDLQKLK 14407
Query: 1997 EALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSRE----QKLASDLKALSEKEESTK 1830
E A ++++ + + L+ N E V E+ LS+++E ++ ++++ + K +
Sbjct: 14408 EECRSAEEEKSVIMESLERRRNSLEKVQSEV-LSLTQEIDHLAQIKTEMQQIEIKMQIQT 14466
Query: 1829 NQLLIQTEQNKQLELEIEK---LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQG 1659
+ Q E + Q++ E ++ G + K E K + I + KL T + EVQ
Sbjct: 14467 RSVATQWETDVQIQQEGQEPIETTGHITKKSEEEISAKKTKQPI--VTKLEDTLTSEVQE 14524
Query: 1658 QQEGILKQDINIEDELARTKEVGRSATD-MKKVNSDAGAKVSGI---LEMLLPMKDDVFS 1491
+ D+ IED +AR K + + D +++ SD ++ +E L K
Sbjct: 14525 MR------DMEIED-VARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEETLKEKSRNEE 14577
Query: 1490 LKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIE 1311
++L + + L N +E + T A+ E + ++ + + I++ L++
Sbjct: 14578 TLLQLLHDKDDLSNTLDEKSKEIENITVTFKRNIAQLETT---IAMMKKDKENIENELLQ 14634
Query: 1310 LKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEE 1131
LK+ Q + E QR + N + + ++ LE K + + K
Sbjct: 14635 LKQTEQ--EREIQRGTDDTSNERENYDEKVTYKTELEDSKEKKKPDRD-SSLKLTDADSA 14691
Query: 1130 RNVVESEHNVLSSEVENLKS----ELKESKDLEGYFLRLFEILLGQHVEVASLDI----E 975
+ E E L ++V+++ ++ ++L +I+L + A D+ E
Sbjct: 14692 KTDGEREAQTLETKVQDVLQLTDYTTQDQEELHDEMENKMKIIL--ELNEAKKDLQKLKE 14749
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEAL---YEYHDYERKNVSGSRAEAMSVLISKS 804
CR AEE+ I++ L RN K+++E L E + + E + ++S
Sbjct: 14750 ECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRS 14809
Query: 803 LGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEK--AEMFETKSREAQQMANK 630
+ + Q +E + + K + E +K + ++ +T + E Q+M +
Sbjct: 14810 VATQWETDVQIQQGQEATETTGHITKK-SEEEISAKKTKQPTVTKLEDTLTSEVQEMRDS 14868
Query: 629 LEEMQQTLSDM 597
L + + ++ M
Sbjct: 14869 LNKEMEDVARM 14879
Score = 62.0 bits (149), Expect = 1e-06
Identities = 117/589 (19%), Positives = 235/589 (39%), Gaps = 54/589 (9%)
Frame = -1
Query: 2108 LQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQ 1929
L++ + + V TER EL + L+ + +++ ++ +EK DLE Q
Sbjct: 12648 LESGKDETDGLTEVHTTERRELEITKLALQSEQQEIEKIRQDIDREKNDLEKYRSDLEKQ 12707
Query: 1928 -------KETVSKELALSVSREQKLASDLKALSEKEESTKNQL--------LIQTEQNK- 1797
K+ + E A + + + K+ E+ ES + QL I E NK
Sbjct: 12708 YEEMEICKQNIENERAELEIDLENIIIETKSKQERLESIEVQLQEKNVQMGTILDELNKR 12767
Query: 1796 QLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCK---LLATKSREVQGQQEGILK---Q 1635
Q EL+ K + +QM +T + +E I L K ++ E+Q Q+E + K Q
Sbjct: 12768 QEELDAIKAKTQREKEQMGHTEELEKDELIAILQKREEIVKRHMEEIQNQREELQKEKDQ 12827
Query: 1634 DINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSL---------KE 1482
N++ EL + G+ +M ++ ++ + + L + + F L E
Sbjct: 12828 FGNMQAELQK----GQLEMEMHQLMLNSERDELNGMRVNLEKQKEEFELMQQNLESRRPE 12883
Query: 1481 EVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQ---HILIE 1311
+L +I + + + L + Q+ + +E R +++ +++ E+ Q L E
Sbjct: 12884 SLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKIKQIEGEIKTKQIEMACLEE 12943
Query: 1310 LKRKNQTLQ--------DESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQ 1155
LK+K Q E Q +EL K ++ + L Q K EL
Sbjct: 12944 LKQKELDEQKNMRECENQELQMRREELAKMKTEIDIERDEIQKLRKQYEKEKCELEQIKP 13003
Query: 1154 KAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIE 975
+ + E+ E +H+ + +++LK E +E +E D++
Sbjct: 13004 DLQKREPEKIDAEVQHDEIHGGIDSLKEEREE-------------------IEKMKADLQ 13044
Query: 974 SCRFAEEKLMRILD-ELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVL-ISKSL 801
+ E + I+ E L + A+++ A+ + KN+ + ++L ++K
Sbjct: 13045 NKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIEAILKVTKKQ 13104
Query: 800 GN--GRANQREFQNKEEDSSGVDLLKNKCTRL--------EFQVQKLSEKAEMFETKSRE 651
N + N+ + K E + +L+ + T L EF + K+ E+ +T R
Sbjct: 13105 KNYLEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKMEEREAERKTIERV 13164
Query: 650 AQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGE 504
+MA + E++++ ++ + E T+ +SE++ E
Sbjct: 13165 MDEMAEEHEKIKKEREELVNMEEEIKKQRRVLEESMNEMTKKKSELQHE 13213
Score = 60.5 bits (145), Expect = 3e-06
Identities = 107/584 (18%), Positives = 246/584 (42%), Gaps = 26/584 (4%)
Frame = -1
Query: 2291 RLYEEEKQHTIELQENFNALRQKNEDI-CLKIE---ANNNLLEQKDN---IIVELSHKLQ 2133
RL EE + Q+ A + + D +K E AN L +Q++ I E+ + +
Sbjct: 7027 RLNEEINIQKVNQQKQATAFQMEKTDFERIKTEIDQANKELADQQEKNKKTITEMQKERE 7086
Query: 2132 ENEEQRSALQNDMQSV-EQMHAVSQTERE--ELNRQLVLLRDDVNHLKEALSMAV----- 1977
EE R+ + ++++ + ++S E E +L ++ + +++ LK + M +
Sbjct: 7087 TLEEMRANISKQVETITNENKSLSSRESELAKLQEDILQQQQEMDELKNTIMMEMCQLDQ 7146
Query: 1976 --DDRAFMEKQLQDLENQKET----VSKELALSVSREQKLASDLKALSEKEESTKNQLLI 1815
D ++K++ DL + +T V +E +++ + + SD+ +L ++E+ + L
Sbjct: 7147 RQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLK 7206
Query: 1814 QTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQ 1635
E+ +E E E L +L + +K E L + ++ +++ + K
Sbjct: 7207 LNEEKDLIEKERELLTKNLDHTDKDKMDMKRELEN-------LKVEKETIKNEKKELEKM 7259
Query: 1634 DINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSL 1455
I+++ + KE D + + + A+ + L++ + F EE L
Sbjct: 7260 KISLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFI--EERLDQTEKK 7317
Query: 1454 RNDAQMVQVALEQ----MQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTL 1287
R + ++ +Q TK E+ + E E+ R + E++ + L ++ N
Sbjct: 7318 RRKTYYTEDLFQEEKTDLQKTKEEINYDRE----EIYRQRTELNKEKETLKQMHTSNLKE 7373
Query: 1286 QDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEH 1107
+ ++ +++ L+ + ++ L+++ R + ++ ++ ++ + +++E
Sbjct: 7374 IENIEKEKEKIQRTWNELDQIRAE---LQNKQRDMDDTTNIMMKEKAELARDLENLQNEK 7430
Query: 1106 NVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL 927
+ L EN++ +KE L+ L+ E L + + E + + L I E+
Sbjct: 7431 DELQKSRENIQKLMKE---LQEERLKTSEALNKERQQFT----EEIKLKNDSLDEIQAEI 7483
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRAN-QREFQNKEEDS 750
R + A + ++ + + + R + S RAN QRE + D
Sbjct: 7484 D--RQKRALVTDKEIITKQMMDLQKTQDVRRQ------SDESDIARANLQRE--RESLDQ 7533
Query: 749 SGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEM 618
V++LK K LE + +L E+ + ET+ + + + E+
Sbjct: 7534 LSVEILKQK-QDLERERDELLEQWRLVETQKMDNENVKQLKTEL 7576
Score = 59.7 bits (143), Expect = 5e-06
Identities = 119/587 (20%), Positives = 244/587 (41%), Gaps = 18/587 (3%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
KE + EE + EL+E Q+N+++ E +LLE++ + +LQ+
Sbjct: 12217 KEYESIIEETNRKRTELEEIEVDQSQQNKNV----ETMKDLLEKERKDTEKEREELQKQA 12272
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQ----LVLLRDDVNHLKEALSMAVDDRAFME 1956
+ + E+M S E ++L Q ++ RDD+ KE + ++ ++
Sbjct: 12273 DDLEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQ 12332
Query: 1955 KQLQDLENQKETVSKELA---LSVSREQK-LASDLKALSEKEESTKNQLLIQTEQNK-QL 1791
K++Q+ +N+ E + EL + + +EQK L L ++E+ + + +++ + K Q
Sbjct: 12333 KEIQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLE---IVRVDYEKHQQ 12389
Query: 1790 ELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDEL 1611
++E ++ ++ +++ + K L+ K E G+LK+++
Sbjct: 12390 QIEEMRVKTKMERDELDQLMAK----------MLMDRKENERSKDMIGLLKKEM------ 12433
Query: 1610 ARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQ 1431
+ K N DA E L K + + K+++ ++ +A V+
Sbjct: 12434 -----------EQTKFNLDAQE------EELKLEKQKIQNEKKDLEMFKAEIKREASEVK 12476
Query: 1430 VALEQM--QDTKS-ELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAK 1260
EQ +DTK+ E E + Q V + E + IQ + E+KR + E + K
Sbjct: 12477 TLKEQQLEKDTKAFEALKEEHLPGQFVQQKGGEFERIQ--IDEVKR----ILSEIHKEKK 12530
Query: 1259 ELWNAKARLNNVMSKNINLESQNRSLKAELHL--QAQKAFQIQEERNVVESEHNVLSSEV 1086
EL K L + + ++S+ S + ++ L A + +++ +V S+ +
Sbjct: 12531 ELERNKQILEHQREALLEIKSKQPSERLDVILVSSATQTSDLEDIPDVSASQGETVEKHT 12590
Query: 1085 ENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMR----ILDELICL 918
+ +K E S E Y + + L Q + E + A+ ++ I D I +
Sbjct: 12591 DIIK-EYTTSIPKEEYEI---DKLKQQGDKKLKSTREDTKMADTEVTTQYKYIPDPSIMM 12646
Query: 917 RNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVD 738
+ E+ K + + L E H ER+ + ++ A Q E Q E+ +D
Sbjct: 12647 KLESGKDETDGLTEVHTTERRELEITKL---------------ALQSEQQEIEKIRQDID 12691
Query: 737 LLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDM 597
KN + ++K E+ E+ + Q + N+ E++ L ++
Sbjct: 12692 REKNDLEKYRSDLEKQYEEMEICK------QNIENERAELEIDLENI 12732
>ref|XP_005159738.1| PREDICTED: titin isoform X1 [Danio rerio]
Length = 15746
Score = 126 bits (317), Expect = 4e-26
Identities = 169/712 (23%), Positives = 304/712 (42%), Gaps = 41/712 (5%)
Frame = -1
Query: 2258 ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQ 2079
+LQ +L + E + L EA N E I +L K +E E+ + Q+D Q VE+
Sbjct: 4872 DLQHKMFSLDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVEE 4931
Query: 2078 MHAVSQTER-------EELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLE----- 1935
M A Q ER EE NR+ ++L + +KE + DR +EK+ DLE
Sbjct: 4932 MTAQIQKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSK 4991
Query: 1934 --NQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGS 1761
KE + K+ + ++ QK DL+ ++EK + + Q EQ KQ + E+++L
Sbjct: 4992 LLRAKENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTE 5051
Query: 1760 LQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQ---EGILKQDINIEDELARTK-EV 1593
+Q Q E L+ E I L + E+ QQ I++ N +L + K E
Sbjct: 5052 IQNLQQE---LEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEET 5108
Query: 1592 GRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINS--------LRNDAQM 1437
+M+K D + E L MK L+++VL + S L +A
Sbjct: 5109 EEQKQEMEKEKHDFDQSRKSLDEDLKMMK-----LQKQVLEDEKSKLEQMKIELEREAVE 5163
Query: 1436 VQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQ-TLQD--ESQRN 1266
++ E++Q+ + L E +E L E +L E+K N+ TL D + N
Sbjct: 5164 IRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKSN 5223
Query: 1265 AKEL-WNAKARLNNVMSKNINL---ESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVL 1098
+E+ N + +V +K NL E + R L+AE+H Q + +I++E+ +ESE +
Sbjct: 5224 LEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQR---EIEKEKINIESERAAI 5280
Query: 1097 SSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICL 918
+VE+L+ ++ I L + E LD E+ +E L ++ EL
Sbjct: 5281 IKDVEDLQHKI---------------ICLDRDAESLKLDREAFENEKEVLKQMKTELERE 5325
Query: 917 RNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVD 738
+E K+K E HD + R E M+ I K ++ E N E+++ D
Sbjct: 5326 ADEIEKIKLET---QHDRQ-------RVEEMAAQIQK-------DRDEINNLIEETNRKD 5368
Query: 737 LLKNKCTR-LEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXI 561
++ N+ R +E +++ + +M E + + ++ ++L ++++ L
Sbjct: 5369 MVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQ---------KEN 5419
Query: 560 RVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPL------IQXXXXX 399
+ ++KE L + KH+E ++ + D+ T + ++
Sbjct: 5420 TLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEI 5479
Query: 398 XXXXXXKIDTRTSETQEIDTLMDDNRKYW-NRVSHFTKQTQSLQNSVQELQQ 246
++D R SE + T M+D + N K + ++ QE+++
Sbjct: 5480 IMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEK 5531
Score = 101 bits (251), Expect = 2e-18
Identities = 162/831 (19%), Positives = 370/831 (44%), Gaps = 70/831 (8%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLK--IEANNNLLEQKDNIIVELSHKLQE 2130
+E++ +++ +Q E + +QK +D+ + ++ + LE+ ++E+ K +
Sbjct: 10948 EEINHKWKQLQQRIDEFDAQVS--KQKEQDLPKEKGMKEDRKSLEETKANVIEMKTKAEP 11005
Query: 2129 NE---EQRSALQNDMQSVEQMHAVSQTEREELNR---QLVLLRDDVNHLKEALSMAVDDR 1968
E E+ + + + E++ + +TER+EL + +L +R +++H ++ L+ D
Sbjct: 11006 EEIKKEKEKENEEEEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQKKLN---DYM 11062
Query: 1967 AFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALS------EKEESTKNQLLIQTE 1806
+E++ +DLE K + K+ +L + ++ + EK + +L+++ E
Sbjct: 11063 KMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVEVE 11122
Query: 1805 -QNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDI 1629
Q K ++L+ E+L Q E LL K+ + + + E++ ++E + + +I
Sbjct: 11123 EQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKKVDEEIKKERETLREMEI 11182
Query: 1628 NIEDELARTK----EVGRSATDMKKVNSDAGAKVSGILEMLLPMK---DDVFSLKEEVLG 1470
+++ E + E R D++K+++D I E L +K D + +EE+
Sbjct: 11183 HLKKEKEELRSIIEETQRRKEDLEKMSTD-------INEQKLHLKNQRDLLEQEREEINH 11235
Query: 1469 NINSLRN-----DAQM-----------VQVALEQMQDTKSELF-AEAEIRAQEVLRLQAE 1341
+ L+ DAQ+ ++ + +++TK+ + + + QE+++ + E
Sbjct: 11236 EMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEE 11295
Query: 1340 VDAIQ-HILIELKRKN-QTLQDESQRNAKELWNAKARLNNVMSKNINLESQN-RSLKAEL 1170
D + +++E++R+ ++ E +R E+ + + +LN+ K I E ++ +K+E+
Sbjct: 11296 EDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLND-DKKIIEQEKEDLEKMKSEI 11354
Query: 1169 HLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDL-EGYFLRLFEILLGQHVEV 993
Q Q Q++EER+ E ++ + +++E + +++ SK++ + +++ E ++
Sbjct: 11355 MTQRQ---QMEEERS--ELDNKIKQTDLE--RHDIENSKEIVQKLMVKVEEQRKDIRLQK 11407
Query: 992 ASLDIESCRFAEEKLMRILDELICLRNENAKLK---------NEALYEYHDYERKNVSGS 840
LDIE + A+E+ + ++ L+NEN ++K E L E + RK
Sbjct: 11408 EELDIERQKIADEQGL-VVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEM 11466
Query: 839 RA-------------EAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQV 699
R+ E MS ++K NQR+ +E + + +K T+L+ ++
Sbjct: 11467 RSVIEETQRRKKEDLEKMSTDVNKQ-NQDLMNQRDLLKQEREE-----INHKWTQLQQRI 11520
Query: 698 Q----KLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENT 531
++S++ E TK ++ ++ LEE + + +M + + ++E
Sbjct: 11521 DEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKE-EEEVM 11579
Query: 530 RLRSEM-KGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSET 354
R + EM K EL +S R S I DD +I+ +I + +
Sbjct: 11580 RAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQM 11639
Query: 353 QEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSI 174
+E + +D N++ + ++NS + +Q+ M +
Sbjct: 11640 EEERSELD------NKIKQTDLERHDIENSKEIVQKL-------------------MVEV 11674
Query: 173 EKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEEV 21
E+Q K++ + +L ++ + G N N E+ ++DEE+
Sbjct: 11675 EEQRKDIRLQKEELDIERQKIADEQ--GLVVQNKAKLQNENERIKEMDEEI 11723
Score = 100 bits (250), Expect = 2e-18
Identities = 148/763 (19%), Positives = 321/763 (42%), Gaps = 12/763 (1%)
Frame = -1
Query: 2276 EKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQND 2097
E QH + E A QK+ D KI NNL+E+ + + L+ K ++ E++ ++Q+D
Sbjct: 6208 ETQHDRQRVEEMTAQIQKDRD---KI---NNLIEETNRKDMVLNEKNRDIEKKIKSIQSD 6261
Query: 2096 MQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETV 1917
+E+ + + E+ +L +++D+ KE + A ++K+ +DLE E +
Sbjct: 6262 KDMLEK----EKHDLEKTRSELYKVKEDLEKQKE------NTLAQIQKEREDLEKMNENI 6311
Query: 1916 SKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQME- 1740
++E+ +E+++ L + + +N +Q E K+ E+ I K L +Q E
Sbjct: 6312 TREMHEIKHQEEQMNQKQDELDQLKTEIQN---LQQELEKEKEI-IMKARSQLDRRQSEL 6367
Query: 1739 ---NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMK 1569
T + D E + + K L E++ Q++ + K+ N++ E + K
Sbjct: 6368 DKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQK 6427
Query: 1568 KVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELF 1389
+V + K+ + L DD+ +KEE +N Q+++ E+++ + ++
Sbjct: 6428 QVIEEEKNKLEQMKIELEREADDIRKIKEET-------QNKRQILEKMAEELKKERKDVA 6480
Query: 1388 AEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNI 1209
AE +E L A + + +L+++ L++ + +K+ + + + + +
Sbjct: 6481 HLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLRED 6540
Query: 1208 NLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLR 1029
LE L+AE+H Q + + E++ +E E + +VE+L+S++
Sbjct: 6541 ELE----QLQAEIHKQQS---ETEIEKSNIERERAAIIKDVEDLQSKI------------ 6581
Query: 1028 LFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNV 849
I L + E LD E+ +E+L ++ EL +E K+K E +ER+ V
Sbjct: 6582 ---ISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLET-----QHERQRV 6633
Query: 848 SGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMF 669
A+ M + ++ + + K+E D + L+ ++ + + ++
Sbjct: 6634 EEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVL 6693
Query: 668 ETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRV-RSLKKENTRLRSEMKGELTPS 492
E + + +QM LE +S + ++ +LK+E L E+K
Sbjct: 6694 EEEKNKLEQMKIGLEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIK------ 6747
Query: 491 RSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYW 312
R+ + +I + +E +Q + R + +++I+ + ++ K
Sbjct: 6748 -----RKNQVLDKIKVANESTLADLQKEKRILE------EMRENISKQIEDIENEKEKSK 6796
Query: 311 NRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQL 132
R K +Q E+ + + M ++K+ +++ + + ++
Sbjct: 6797 LREDELKKLQTEVQKQQSEIDMEKTNIESERAAMIREKQNM-MTELKKKSEDVEMQMKEI 6855
Query: 131 VE-----HNTR--LKKDVKFGFAWANSMHDLNGQEQKLKVDEE 24
+ HN R LKKDV+ + + + LK+D+E
Sbjct: 6856 LTEKELLHNDRNLLKKDVE---DLQQKLMSIERDSESLKLDKE 6895
Score = 100 bits (249), Expect = 3e-18
Identities = 155/794 (19%), Positives = 326/794 (41%), Gaps = 68/794 (8%)
Frame = -1
Query: 2282 EEEKQHTIELQENFN-ALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQ---- 2118
EE+KQ + ++N + +++ +ED+ + ++ ++E++ N + ++ +LQ ++
Sbjct: 3983 EEQKQEMEKERDNMDQSIKSLDEDLKM-MKLQKQVIEEEKNKLEQMKFELQREADEIRKI 4041
Query: 2117 RSALQNDMQSVEQM------------HAVSQTEREE--LNRQLVLLRDDVNHLKEALSMA 1980
+ QN+ QS+E+M H T+RE+ L+ V + + L+ +
Sbjct: 4042 KEETQNERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRIL 4101
Query: 1979 VDDRAFMEKQLQDLENQKETVS------KELALSVSREQKLASDLKALSEKEEST----- 1833
+ R + KQ +D+EN+KE K+L V ++Q K E E +
Sbjct: 4102 EEMRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREK 4161
Query: 1832 KNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATK-------- 1677
+N + ++++ +E++++++ ++ + ++ LLK E + KL++ +
Sbjct: 4162 QNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQ--KLMSIERDSESLKL 4219
Query: 1676 SREVQGQQEGILKQ---DINIE-DELARTK---EVGRSATDMKKVNSDAGAKVSGILEML 1518
RE G ++ +LKQ D+ I+ DE+ + K + R + K L +
Sbjct: 4220 DREAFGNEKEVLKQMKTDLQIQADEIEKIKLETQHDRQRVEEKTAQIQKDRDEINNLIVE 4279
Query: 1517 LPMKDDVFS-LKEEVLGNINSLRNDAQMVQVALEQMQDTKSELF-------AEAEIRAQE 1362
KD V + + ++ I S+++D M++ ++ T+SEL + EI ++
Sbjct: 4280 TNRKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLEKTRSELARAKENLETQREIERKD 4339
Query: 1361 VLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSL 1182
+ +++ + H + + + + QDE + E+ N + L + SQ
Sbjct: 4340 IEKMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDLR 4399
Query: 1181 KAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-KESKDLEGYFLRLFEILLGQ 1005
++EL Q I E + + E E K E+ KE D + L E L
Sbjct: 4400 QSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLKMM 4459
Query: 1004 HVEVASLDIESCRFAEEK--LMRILDELICLRNE--NAKLKNEALYEYHDYERKNVSGSR 837
++ ++ E + + K L R DE+ ++ E N + E + E ER+++S
Sbjct: 4460 KLQKQVIEEEKSKLKQMKIELEREADEIRKVKEETQNERQIFEKMTEALKKEREDLSEDA 4519
Query: 836 AEAMSVLISKSLGN---------GRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSE 684
VL + N R+N +E +E S + ++NK ++ + +KL +
Sbjct: 4520 KRKNQVLDEMKVANESTLADILRERSNLQEM--RENISKQTEDVENKKEKIRLREEKLKQ 4577
Query: 683 -KAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKG 507
+AE+ + +S ++ +N E + D+ SLK + +E K
Sbjct: 4578 LQAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENE-KE 4636
Query: 506 ELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDD 327
EL ++ RE I++I + + + ++ T + M++
Sbjct: 4637 ELKQMKTELEREADEIEKIKLETQHERQRVE-----------------EMTADFMETMNN 4679
Query: 326 NRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNI 147
RK N K + +Q QE+++ S++K LK + +
Sbjct: 4680 ERKQLN------KNKEEMQEQKQEMEKERHDMDQ------------SRKSLDKNLKMMKL 4721
Query: 146 HVMQLVEHNTRLKK 105
+ E +L++
Sbjct: 4722 QKQVIEEEKNKLEQ 4735
Score = 98.2 bits (243), Expect = 1e-17
Identities = 169/821 (20%), Positives = 350/821 (42%), Gaps = 72/821 (8%)
Frame = -1
Query: 2282 EEEKQHTI-ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
E++K++T+ ++Q+ L + NE+I ++ + EQ ++ K E ++ ++ +
Sbjct: 6287 EKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQ-------MNQKQDELDQLKTEI 6339
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
QN Q +E+ + R +L+R+ L ++ + + ++R ++K +++E QK
Sbjct: 6340 QNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQK 6399
Query: 1925 ETVSKELALSVSREQKLASDLKALS------EKEESTKNQLLIQTE-------------Q 1803
+ + KE + L DLK + E+E++ Q+ I+ E Q
Sbjct: 6400 QEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQ 6459
Query: 1802 NKQ--LELEIEKL--------YGSLQMKQMENTL--LKDGNEKIYDLCKLLATKSREVQG 1659
NK+ LE E+L + + K+ +N+L +K NE + L KS ++
Sbjct: 6460 NKRQILEKMAEELKKERKDVAHLAEDTKREKNSLDEMKVANES--SMADLQKEKS-NLEE 6516
Query: 1658 QQEGILKQDINIEDE----LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFS 1491
+E I KQ +IE E R E+ + ++ K S+ + S I + DV
Sbjct: 6517 MKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVED 6576
Query: 1490 LKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIE 1311
L+ +++ SL DA+ +++ E ++ K EL Q L+ E D I+ I +E
Sbjct: 6577 LQSKII----SLDRDAESLKLDREAFENEKEEL-------KQMKTELEREADEIEKIKLE 6625
Query: 1310 LKRKNQTLQDESQRNAKELWNAKARL--NNVM---------SKNINLESQNRSLKAELHL 1164
+ + Q +++ + + + N + +L N VM K +++ +SL +L +
Sbjct: 6626 TQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKM 6685
Query: 1163 QAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASL 984
+ ++EE+N +E L E + + S++KE E L L + E +
Sbjct: 6686 MKAQKQVLEEEKNKLEQMKIGLEREADEI-SKIKEETQNERQNLEKMANALKEEREYLAE 6744
Query: 983 DIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKS 804
+I ++ ++LD++ K+ NE+ E++ + E M ISK
Sbjct: 6745 EI-------KRKNQVLDKI--------KVANESTLADLQKEKRIL-----EEMRENISKQ 6784
Query: 803 LGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETK--------SREA 648
+ + +N++E S L +++ +L+ +VQK + +M +T RE
Sbjct: 6785 I-------EDIENEKEKSK---LREDELKKLQTEVQKQQSEIDMEKTNIESERAAMIREK 6834
Query: 647 QQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRS-LKKENTRLRSEMKGELTPSRSFKHRE 471
Q M +L++ + + R+ LKK+ L+ ++ S S K +
Sbjct: 6835 QNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIERDSESLKLDK 6894
Query: 470 GSFIKEINIGDEDDTPL------IQXXXXXXXXXXXKIDTRTS----ETQEIDTLMDDNR 321
+F E + T L I+ +++ +T+ E +EI+TL+++ +
Sbjct: 6895 EAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIK 6954
Query: 320 KYWNRV----SHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDM--NSIEKQLK 159
K + + + K+ +++++ +L++ I N++EK K
Sbjct: 6955 KKRDIIDESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQQKRNALEKMSK 7014
Query: 158 ELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLK 36
E++ M+L + KK+++ MH ++Q+ K
Sbjct: 7015 EISRDRMKLEDE----KKEIQLAREELERMHGDMQRQQEAK 7051
Score = 97.1 bits (240), Expect = 3e-17
Identities = 121/592 (20%), Positives = 267/592 (45%), Gaps = 29/592 (4%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQ----KDNIIVELSHKLQ 2133
E+ ++ EE + L++ AL+++ ED+ + + NN +L++ ++ + ++ +
Sbjct: 5163 EIRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKS 5222
Query: 2132 ENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK 1953
EE R + + VE + +EL + + +++ +RA + K
Sbjct: 5223 NLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIK 5282
Query: 1952 QLQDLENQKETVSKEL-ALSVSR-----EQKLASDLKALSEKEESTKNQLLIQTEQNKQL 1791
++DL+++ + ++ +L + R E+++ +K E+E ++ ++T+ ++Q
Sbjct: 5283 DVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIKLETQHDRQ- 5341
Query: 1790 ELEIEKLYGSLQMKQME-NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDE 1614
+E++ +Q + E N L+++ N K D+ +L K+R+++ + + I +D
Sbjct: 5342 --RVEEMAAQIQKDRDEINNLIEETNRK--DM--VLNEKNRDIEEKIKSIQSD----KDM 5391
Query: 1613 LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
L + K D++K S+ L +K+D+ KE L I R D
Sbjct: 5392 LEKEKH------DLEKTRSE-----------LYKVKEDLEKQKENTLAEIQKERED---- 5430
Query: 1433 QVALEQMQDTKSELFAEAEIRAQEVLRLQAEVD----AIQHILIEL-KRKNQTLQDESQR 1269
LE+M + + E + + +++ + Q E+D IQ++ EL K K ++D SQ
Sbjct: 5431 ---LEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQL 5487
Query: 1268 NAK--ELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLS 1095
+ + EL + +N++M N Q K E+ Q Q ++++ER+ ++ L
Sbjct: 5488 DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQ---EMEKERDNMDQSRKSLD 5544
Query: 1094 SEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLR 915
+ + +K + K+ + E L +I L + + S E + ++L ++ +ELI +
Sbjct: 5545 EDQKKMKLQ-KQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREK 5603
Query: 914 NENAKLKNEALYEYHDYERKNVSGSRAEA---MSVLISKSLGNGRANQREFQNKEEDSSG 744
A L + E + V+ + A I + + + +E+ + E++ S
Sbjct: 5604 ESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENISKLKEYIDNEKEKS- 5662
Query: 743 VDLLKNKCTRLEFQVQKLSEKAEMFETK--------SREAQQMANKLEEMQQ 612
L +++ +L+ +VQK K +M +T RE Q M +L++ +
Sbjct: 5663 -KLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKKSE 5713
Score = 96.7 bits (239), Expect = 4e-17
Identities = 117/620 (18%), Positives = 263/620 (42%), Gaps = 66/620 (10%)
Frame = -1
Query: 2282 EEEKQHTI-ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
E++K++T+ E+Q+ L + NE+I +++ + EQ + K E ++ ++ +
Sbjct: 3874 EKQKENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQ-------MKQKQDELDQLKTEI 3926
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
QN Q +E+ + +R EL+ + L ++ + + ++R ++K +++E QK
Sbjct: 3927 QNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQK 3986
Query: 1925 ETVSKELALSVSREQKLASDLKAL--------SEKEESTKNQLLIQTEQNKQLELEIEKL 1770
+ + KE + L DLK + EK + + + +Q E ++ +++ E
Sbjct: 3987 QEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQ 4046
Query: 1769 YGSLQMKQMENTLLKDGNEKIY------------DLCKL--------LATKSREVQGQQE 1650
+++M L+K+ + ++ D ++ L + R ++ +E
Sbjct: 4047 NERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRILEEMRE 4106
Query: 1649 GILKQDINIEDELARTK-------------EVGRSATDMKKVNSDAGAKV-----SGILE 1524
I KQ +IE+E ++K + +S DM+K N ++ V ++
Sbjct: 4107 NISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQNMMT 4166
Query: 1523 MLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFA-------------- 1386
L +DV +E+L L ND+ +++ + M+D K +L +
Sbjct: 4167 ELKKKSEDVEIQMKEILTEKELLENDSNLLK---KDMEDLKQKLMSIERDSESLKLDREA 4223
Query: 1385 ---EAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSK 1215
E E+ Q LQ + D I+ I +E + Q +++++ + K+ + K
Sbjct: 4224 FGNEKEVLKQMKTDLQIQADEIEKIKLETQHDRQRVEEKTAQIQKDRDEINNLIVETNRK 4283
Query: 1214 NINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELK-ESKDLEGY 1038
++ L +R ++ ++ +++ER+ +E + L+ ENL+++ + E KD+E
Sbjct: 4284 DMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLEKTRSELARAKENLETQREIERKDIE-- 4341
Query: 1037 FLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYER 858
+ + S ++ + EE++ + DEL L+ E L+ E
Sbjct: 4342 ----------KMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQNLQQE---------- 4381
Query: 857 KNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGV-DLLKNKCTRLEFQVQKLSEK 681
E +I K+ Q E ++ + + + + +KN+ +L+ ++ E+
Sbjct: 4382 -------LEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQ 4434
Query: 680 AEMFETKSREAQQMANKLEE 621
+ E + + Q L+E
Sbjct: 4435 KQEMEKEKHDFDQSRKSLDE 4454
Score = 96.7 bits (239), Expect = 4e-17
Identities = 128/572 (22%), Positives = 261/572 (45%), Gaps = 11/572 (1%)
Frame = -1
Query: 2282 EEEKQHTIELQEN-FNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
+E+ HT EL+++ A+ QK E+I + +E+ N EL + + ++ L
Sbjct: 12948 KEQMGHTEELEKDELIAILQKREEIVKRH------MEEIQNQREELQKEKDQFGNMQAEL 13001
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
Q +E + +ER+ELN V L E + ++ R E L+D+ +K
Sbjct: 13002 QKGQLEMEMHQLMLNSERDELNGMRVNLEKQKEEF-ELMQQNLESRR-PESLLEDILKEK 13059
Query: 1925 ETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQ 1746
+ V +E+A +S+EQ E +N I +E K++E +I+++ G ++ KQ
Sbjct: 13060 KRV-EEMAAQLSKEQ-------------EEFRN---IMSETIKRME-KIKQIEGEIKTKQ 13101
Query: 1745 MENTLLKDGNEKIYDLCK-LLATKSREVQGQQEGI--LKQDINIE-DELAR-TKEVGRSA 1581
+E L++ +K D K + +++E+Q ++E + +K +I+IE DE+ + K+ +
Sbjct: 13102 IEMACLEELKQKELDEQKNMRECENQELQMRREELAKMKTEIDIERDEIQKLRKQYEKEK 13161
Query: 1580 TDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTK 1401
+++++ D L+ P K D +E+ G I+SL+ + + ++ +Q+
Sbjct: 13162 CELEQIKPD--------LQKREPEKIDAEVQHDEIHGGIDSLKEEREEIEKMKADLQNKL 13213
Query: 1400 SELFAEAEIRAQEVLRLQAEVDAIQHILIELK--RKNQTLQDESQRNAKELWNAKARLNN 1227
E +I +E L+ + I+ + +E + ++ LQDE + L K + N
Sbjct: 13214 REAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIEAILKVTKKQKNY 13273
Query: 1226 VMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDL 1047
+ N NL + L+ + ++ ++ ++ E H S++E ++E K +
Sbjct: 13274 LEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEFH---MSKMEEREAERKTIE-- 13328
Query: 1046 EGYFLRLFEILLGQHVEVASLDIESCRFAEE--KLMRILDELICLRNENAKLKNEALYEY 873
R+ + + +H ++ E EE K R+L+E + NE K K+E +E
Sbjct: 13329 -----RVMDEMAEEHEKIKKEREELVNMEEEIKKQRRVLEESM---NEMTKKKSELQHER 13380
Query: 872 HD-YERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQ 696
+ Y++K + + +I+ +R Q+KE++ +LK + +
Sbjct: 13381 SELYKQK-------QQLEDMIASESKRDVDTERSRQDKEDE----QILKREREEIADMKD 13429
Query: 695 KLSEKAEMFETKSREAQQMANKLEEMQQTLSD 600
+L ++ E ET + +E+MQ L+D
Sbjct: 13430 QLLKEKEDVETTKERINREKEHIEKMQSQLND 13461
Score = 95.9 bits (237), Expect = 7e-17
Identities = 121/615 (19%), Positives = 259/615 (42%), Gaps = 8/615 (1%)
Frame = -1
Query: 2291 RLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRS 2112
R+ E + Q + + +E+ ++ ED E N+LE K E K +E EE+
Sbjct: 12074 RIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQ 12133
Query: 2111 ALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLEN 1932
++ ++ + + E E++ QL +R +++H ++ L+ DD+ +E++ +DLE
Sbjct: 12134 EMRVKVE-------MERKEIEQIKSQLERVRSEMDHEQKKLN---DDKKMIEQEKEDLEK 12183
Query: 1931 QKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQM 1752
K + K+ +L +K ++ +N E ++L +E+EK +Q
Sbjct: 12184 MKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENS----KEIVEKLMVEVEKQKHEIQF 12239
Query: 1751 KQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDM 1572
++ E L +KI D LL E Q + E I + D I+ E KE+ +
Sbjct: 12240 QKEE---LDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNLQKE 12296
Query: 1571 KKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSEL 1392
K+ + E L M D+ K++++ + L+ + + + L Q+Q E
Sbjct: 12297 KEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEF 12356
Query: 1391 FAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKN 1212
+ I + + E+D L + ++ +++ +E+ R EL +
Sbjct: 12357 ETTSNILVTTKMEEKTEMD---EKLQQAIKEYESIIEETNRKRTELEEIE---------- 12403
Query: 1211 INLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFL 1032
++ QN++++ L +++ER E E L + ++L+ ++ E D E
Sbjct: 12404 VDQSQQNKNVETMKDL-------LEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSK 12456
Query: 1031 RLFEI---LLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYE 861
R + LL Q + +E +M+ +EL L+ E KNE + E
Sbjct: 12457 RSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKEIQNQKNEMEEIKCELE 12516
Query: 860 RKNVSGSRAEAMSVLISKSLGNGRANQREFQ----NKEEDSSGVDLLKNKCTRLEFQVQK 693
K + + + + +SL ++ + + E+ ++ ++ K ++ +
Sbjct: 12517 TKRIEIIKEQKR---LEESLNTVNEERQYLEIVRVDYEKHQQQIEEMRVKTKMERDELDQ 12573
Query: 692 LSEKAEMFETKSREAQQMANKLE-EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSE 516
L K M ++ ++ M L+ EM+QT ++ ++++ KK+ ++E
Sbjct: 12574 LMAKMLMDRKENERSKDMIGLLKKEMEQTKFNLDAQEEELKLEKQKIQNEKKDLEMFKAE 12633
Query: 515 MKGELTPSRSFKHRE 471
+K E + ++ K ++
Sbjct: 12634 IKREASEVKTLKEQQ 12648
Score = 94.7 bits (234), Expect = 2e-16
Identities = 148/745 (19%), Positives = 307/745 (41%), Gaps = 60/745 (8%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQ------ENFNALRQKNED-----ICLKIEANNN-----LLEQK 2169
E+ R EE ++ + LQ EN A Q+ ED I +KI+ L ++
Sbjct: 9523 EMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQLDKET 9582
Query: 2168 DNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEAL 1989
+ E+ K+++ E + + ++ Q +E + + E++EL ++ L D + L
Sbjct: 9583 KRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREK 9642
Query: 1988 SMAVDDR---AFMEKQLQDLENQKETVSKELALSVS----------REQKLASDLKALSE 1848
++R ++ QL+DL + E V ++L L S ++Q+L + ++
Sbjct: 9643 QETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENK 9702
Query: 1847 KEESTKNQLLIQTEQNKQ-LELEIEKLYGSL-QMKQMENTL--LKDGNEKI--------Y 1704
KE+ + Q +TEQ KQ LE+ K+ +M + L KD EKI +
Sbjct: 9703 KEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDELEKIAYKTNKERH 9762
Query: 1703 DLCKLLATKSREVQG-QQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAK---VS 1536
++ ++ A ++Q +Q+G + QD E + + R ++K N++ + ++
Sbjct: 9763 EVEQMQAELHSQIQAIEQQGQIMQDKQNHLE-EKELSIQRKEEEIKIGNTEFQIEQEHLN 9821
Query: 1535 GILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSEL--FAEAEIRAQE 1362
+LE + D+ ++ ++ N D ++++ ++++ K +L + E + E
Sbjct: 9822 NVLEETNKRQHDLEVMRADIELNKQKNNKDFELLEKIRSELENEKYDLQIWTEQQKHLVE 9881
Query: 1361 V--LRLQAEVDAIQHILIELKRKNQTLQDES---QRNAKELWNAKARLNNVMSKNINLES 1197
V L+ E + ++ + IEL+ K + + E R E+ K ++
Sbjct: 9882 VQLQELEKEKERLEKMEIELQSKREQTEKEKADLNRVNAEIQREKQVIDKKRHMTNRAME 9941
Query: 1196 QNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEI 1017
+ ++K EL + +K IQ E+ +E E ++ E ENL L+E K +
Sbjct: 9942 ELETIKTELKERQEK---IQTEQEKLEEEKLLVQIEAENLNKVLEEIKRQQ--------- 9989
Query: 1016 LLGQHVEVASLDI----ESCRFAEEKLMR---ILDELICLRNENAKLKNEALYEYHDYER 858
+ +E++ D+ E C A E+ R ++E I NENAK + ER
Sbjct: 9990 ---EKLEISEADLKVMKEQCENAREETERKKCDIEEQI-QNNENAK-------HLLEQER 10038
Query: 857 KNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKA 678
K++ + E + + +K LL+ K + Q L ++
Sbjct: 10039 KDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEKEK 10098
Query: 677 EMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELT 498
E K + + N+++ + + ++ + + +E+ R +E KG+L
Sbjct: 10099 EDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGDLE 10158
Query: 497 PSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRK 318
R+ ++ I+E+ + + + + +ID + +++ R
Sbjct: 10159 IMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKERN 10218
Query: 317 YWNRV-SHFTKQTQSLQNSVQELQQ 246
++ S Q Q +++ EL Q
Sbjct: 10219 DLEKMKSELMTQRQQMEDERSELDQ 10243
Score = 94.4 bits (233), Expect = 2e-16
Identities = 129/603 (21%), Positives = 273/603 (45%), Gaps = 37/603 (6%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEE 2121
E+ R +E ++ +E Q + + + I + + NNL+E+ + + L+ K ++ EE
Sbjct: 3781 ELERETDEIEKIKLETQHDRQRVEEMTAQITKERDKINNLIEETNRKDMVLNEKNRDIEE 3840
Query: 2120 QRSALQNDMQSVE-QMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQ 1944
+ ++Q+D +E + H + +T E L +++D+ KE + A ++K+ +
Sbjct: 3841 KIKSIQSDKDMLEKEKHNLEKTRSE-----LYKVKEDLEKQKE------NTLAEIQKERE 3889
Query: 1943 DLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYG 1764
DLE E ++ E+ +E+++ L + + +N +Q E K+ E+ I K
Sbjct: 3890 DLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEIQN---LQQELEKEKEI-IMKDRS 3945
Query: 1763 SLQMKQME----NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKE 1596
L ++Q E T + D E + + KLL E++ Q++ + K+ N++ + E
Sbjct: 3946 ELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQKQEMEKERDNMDQSIKSLDE 4005
Query: 1595 VGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQ 1416
+ K+V + K+ + L D++ +KEE +N+ Q ++ +
Sbjct: 4006 DLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEET-------QNERQSLEKMTKA 4058
Query: 1415 MQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKAR 1236
+ + +L AE +E L A + + +L+R+ + L++ + +K+ +
Sbjct: 4059 LIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRILEEMRENISKQTED---- 4114
Query: 1235 LNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-KE 1059
+ N K+ E + + L+ E+ Q +I E+ +ESE V+ E +N+ +EL K+
Sbjct: 4115 IENEKEKSKLREDELKKLQTEVQKQQS---EIDMEKTNIESERAVMIREKQNMMTELKKK 4171
Query: 1058 SKDLEGYFLRLFEILLGQHV--------------------------EVASLDIESCRFAE 957
S+D+E +++ EIL + + E LD E+ +
Sbjct: 4172 SEDVE---IQMKEILTEKELLENDSNLLKKDMEDLKQKLMSIERDSESLKLDREAFGNEK 4228
Query: 956 EKLMRILDELICLRNENAKLKNEALYEYHDYERK--NVSGSRAEAMSVLISKSLGNGRAN 783
E L ++ +L +E K+K E ++ E K + R E ++++ + + N
Sbjct: 4229 EVLKQMKTDLQIQADEIEKIKLETQHDRQRVEEKTAQIQKDRDEINNLIVETNRKDMVLN 4288
Query: 782 Q--REFQNK-EEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQ 612
+ R+ + K + S D+L+ + LE +L+ E ET+ RE ++ +E+M++
Sbjct: 4289 EMDRDIEEKIKSIQSDKDMLEKERHNLEKTRSELARAKENLETQ-REIER--KDIEKMKK 4345
Query: 611 TLS 603
+S
Sbjct: 4346 NIS 4348
Score = 94.0 bits (232), Expect = 3e-16
Identities = 135/605 (22%), Positives = 286/605 (47%), Gaps = 41/605 (6%)
Frame = -1
Query: 2291 RLYEEEKQHTIELQENF-NALRQKNEDICLKIEANNNLLEQKDNIIVE---LSHKLQENE 2124
R+ E + Q + +E+ N + + E CL+ E N ++E K +E ++ K++E +
Sbjct: 10391 RIDEFDAQVRKQKEEDLTNQKKMEEERKCLE-EVNGKIIEMKTKAELEHHEINQKIEELQ 10449
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNR---QLVLLRDDVNH----LKEALSMAVDDRA 1965
+ + + + E M + ERE+L++ +LV + +V+H L + + M ++
Sbjct: 10450 TLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKE 10509
Query: 1964 FMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLEL 1785
+EK ++ QK+ + KE + ++ Q+ + + + +E + + EQ +++L
Sbjct: 10510 DLEKMKSEIMTQKQEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRHEIQL 10569
Query: 1784 EIEKLYGSLQMKQMENTL-------LKDGNEKIYDLCKLLATKSREVQGQQEGILKQD-- 1632
+ E+L Q E L L++ NE+I ++ +++ K RE + E L+++
Sbjct: 10570 QKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEVI-KKERETLKEMEAHLEKEKE 10628
Query: 1631 --INIEDELARTKE-VGRSATDMKKVNSDAGAKVSGILEM----------LLPMKDDVFS 1491
+I +E R KE + + +TD+K+ N D K +LE L + D F
Sbjct: 10629 EMKSITEETRRQKEDLEKMSTDIKEQNQDL-MKQRDLLEQEKEDINHEWTQLQQRIDEFD 10687
Query: 1490 L-----KEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQ 1326
KEE L ++ + + +LE+ + E+ +AE+ + + + E +
Sbjct: 10688 AQVSKQKEEDLTKQKEMKEERK----SLEETKARIIEMKTKAELEDIKKEKEKEEEEEEM 10743
Query: 1325 HILIELKRKN-QTLQDESQRNAKELWNAKARLNNVMSKNINLESQN-RSLKAELHLQAQK 1152
+ +E+ K ++ E +R E+ + + +LN+ K I E QN +K+E+ Q Q
Sbjct: 10744 RVKVEMDGKELDRIKSELKRERSEIDHEQKKLND-DKKIIEQEKQNLEKMKSEIMKQRQ- 10801
Query: 1151 AFQIQEERNVVESEHNVLSSEVENLKSELKESKDL-EGYFLRLFEILLGQHVEVASLDIE 975
Q++EER+ E E+ + + +E K +++ SK++ + + + E + LDIE
Sbjct: 10802 --QMEEERS--ELENKIKQTYIE--KCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIE 10855
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGN 795
+ A+E+ + I ++ L+NEN +++N L E ER+ + + M + K
Sbjct: 10856 RQKIADEQDLLIQNKSE-LQNENERIRN--LNEIIKKERETL-----KEMEAHLEKKKEE 10907
Query: 794 GRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQ 615
++ E + +ED L+ T + Q + L + ++ E +E +++ +K +++Q
Sbjct: 10908 IKSVSEETRRLKED------LEKMSTDVNKQNKDLMNQRDLLE---QEREEINHKWKQLQ 10958
Query: 614 QTLSD 600
Q + +
Sbjct: 10959 QRIDE 10963
Score = 92.4 bits (228), Expect = 8e-16
Identities = 119/631 (18%), Positives = 280/631 (44%), Gaps = 68/631 (10%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE- 2124
E + + +Q E+++ N L +K EDI + + + + +E+ + E E
Sbjct: 294 ETQKAKDLMEQMKAEIEDEKNELEKKKEDIKRQRDQFEQIKLDLQQVKMEMEQRWHETEK 353
Query: 2123 ---EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFM-- 1959
EQR+ +Q + + ++ + Q REE+ R + + + + + A+++ +
Sbjct: 354 EGLEQRAVIQREKEQLKYLQDEIQRVREEVERNREFSKQEHARISQLRAQALEENNLIEN 413
Query: 1958 --------EKQLQDLENQKETVSKELALS---VSRE----QKLASDLKALSEKEESTKNQ 1824
EK L++++++ E +EL ++ V +E ++ D+++ E ++
Sbjct: 414 KWHDILRKEKDLEEMKHEIERGREELVMNGELVKKEWEKIEQAKVDIQSHMISMEGRVDE 473
Query: 1823 LLIQTEQNKQLELEIEKLYGSLQMKQMENT--LLKDGNEKIYDLCKLLATKSREVQGQQE 1650
+ +TE+ K ++ E+++ +L+ KQ ++T ++ K Y+ + T+ E + + +
Sbjct: 474 IKRETERLKHIKTEMQRDKDALE-KQKDDTRKAKEEAERKRYE----IVTEELEHRARLQ 528
Query: 1649 GILKQDINIEDELARTKEVGRSATDMKK-------------------VNSDAGA---KVS 1536
+ NI E+ R +V ++ +K VN++ A +++
Sbjct: 529 RERDELENIRAEMQRVNDVEKAKILKEKEESIRIREEARQERETTELVNAEIKAEKERLN 588
Query: 1535 GILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVL 1356
E +L + ++ +K E L + N + E+M+ K+E+ + E ++V
Sbjct: 589 QRQEEMLRERQEIERIKHETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVE 648
Query: 1355 RLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNR---- 1188
+Q + ++ +EL+ + + L+ + ++E+ A+ N ++ +ES+ R
Sbjct: 649 EIQKTKEQMEEAKVELEEEREDLERKRDLVSREIEQAEFLRNEILRVKEEMESRWRETET 708
Query: 1187 ---SLKAELHLQAQKAFQIQEE-----RNVVESEHNVL--SSEVENLKSELKESKD---L 1047
L+A+ + ++ +++EE +N+ ES+ ++ ++ LK E++E K +
Sbjct: 709 EEVELRAKTQHELERLEKLREETERSQKNIEESKIELMLWKESLDKLKGEMEEDKHVVIM 768
Query: 1046 EGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNE----NAKLKNEALY 879
+ + E L +E ++ + EK+ LDE+ +RNE +A++++
Sbjct: 769 QMNEAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQHAEMEDWFRV 828
Query: 878 EYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQV 699
+ E N++ +L+ K + + +R ++ E D ++ K LE Q+
Sbjct: 829 VNKEKEEANLAKLAVHEAEMLLKKQM--EESEKRRYEMITEALEQRDEIQKKAEELE-QI 885
Query: 698 QKLSEKAEMFETKSR--EAQQMANKLEEMQQ 612
K ++A K R E + + LE+ QQ
Sbjct: 886 NKEIQRARQELEKMRYFEKESLQKMLEDTQQ 916
Score = 92.0 bits (227), Expect = 1e-15
Identities = 142/718 (19%), Positives = 312/718 (43%), Gaps = 33/718 (4%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEAN----NNLLEQKDNIIVELSHKLQ 2133
E+ R +E ++ +E Q + RQ+ E++ +I+ + NNL+E+ + + L+ K +
Sbjct: 5321 ELEREADEIEKIKLETQHD----RQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNR 5376
Query: 2132 ENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK 1953
+ EE+ ++Q+D +E+ + + E+ +L +++D+ KE + A ++K
Sbjct: 5377 DIEEKIKSIQSDKDMLEK----EKHDLEKTRSELYKVKEDLEKQKE------NTLAEIQK 5426
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEK 1773
+ +DLE E +++E+ +E+++ L + + +N +Q E K+ E+ I K
Sbjct: 5427 EREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQN---LQQELEKEKEI-IMK 5482
Query: 1772 LYGSLQMKQME----NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 1605
L ++Q E T + D E + + K L E++ Q++ + K+ N++
Sbjct: 5483 DRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKS 5542
Query: 1604 TKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVA 1425
E + K++ + K+ + L D++ +KEE +N Q ++
Sbjct: 5543 LDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEET-------QNKRQRLEKM 5595
Query: 1424 LEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNA 1245
E++ K L AE E L A + + +L+R+ L +E + N +L
Sbjct: 5596 TEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSIL-EEMRENISKL--- 5651
Query: 1244 KARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL 1065
K ++N K+ E + + L+ E+ Q K I E+ +ESE + E +N+ +EL
Sbjct: 5652 KEYIDNEKEKSKLREDELKKLQTEVQKQQSK---IDMEKTNIESERAAMIREKQNMMTEL 5708
Query: 1064 -KESKDLEGYFLRLFEILLGQHV-----EVASLDIESCR----FAEEKLMRILDELICLR 915
K+S+D+E +++ EIL + + ++ + D+E+ + E R+ +
Sbjct: 5709 KKKSEDVE---IQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFE 5765
Query: 914 NEN---AKLKNEALYEYHDYERKNV----SGSRAEAMSVLISKSLGNGRANQREFQNKEE 756
NE ++K + + + E+ + R E M+ I K + + N E
Sbjct: 5766 NEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQK-------ERDKINNLIE 5818
Query: 755 DSSGVDLLKNKCTR-LEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXX 579
+++ D++ N+ R +E +++ + +M E + ++ ++L ++++ L
Sbjct: 5819 ETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQ------ 5872
Query: 578 XXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPL------I 417
+ ++KE + + KH+E ++ + D+ T + +
Sbjct: 5873 ---KENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQEL 5929
Query: 416 QXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYW-NRVSHFTKQTQSLQNSVQELQQ 246
+ + D R SE + T M+D + N K + ++ QE+++
Sbjct: 5930 EKEKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEK 5987
Score = 91.7 bits (226), Expect = 1e-15
Identities = 146/693 (21%), Positives = 299/693 (43%), Gaps = 77/693 (11%)
Frame = -1
Query: 2282 EEEKQHTI-ELQENFNALRQKNEDICLKI-------EANNNLLEQKDNIIVELSHKLQEN 2127
E++K++T+ E+Q+ L + NE+I ++ E N ++ D + E+ + QE
Sbjct: 5414 EKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQEL 5473
Query: 2126 EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL 1947
E+++ + D ++ + EL++Q + D + +K D+ ME+Q
Sbjct: 5474 EKEKEIIMKDRSQLD-------LRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQK 5526
Query: 1946 QDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLY 1767
Q++E +++ + + S+ +QK K + E+E++ Q+ I+ E+ EI K+
Sbjct: 5527 QEMEKERDNMDQS-RKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREAD---EISKIK 5582
Query: 1766 GSLQ-----MKQMENTLLKD------------GNEKIYDLCKL-----LATKSRE---VQ 1662
Q +++M L+++ +KI D K+ +A RE ++
Sbjct: 5583 EETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILE 5642
Query: 1661 GQQEGI--LKQDINIEDELARTKE-----------VGRSATDMKKVN--SDAGAKVSGIL 1527
+E I LK+ I+ E E ++ +E +S DM+K N S+ A +
Sbjct: 5643 EMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQ 5702
Query: 1526 EMLLPMK---DDVFSLKEEVLGNINSLRNDAQMVQVALEQMQ--------DTK-----SE 1395
M+ +K +DV +E+L L ND +++ +E +Q D+K E
Sbjct: 5703 NMMTELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDRE 5762
Query: 1394 LFA-EAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMS 1218
F E E Q LQ + D I+ I +E + Q +++ + + KE +
Sbjct: 5763 AFENEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNR 5822
Query: 1217 KNINLESQNRSLKAELHLQAQKAFQIQEERNVVESE-HNV--LSSEVENLKSELKESKDL 1047
K++ L +NR ++ +K IQ +++++E E HN+ SE+ +K +L++ K+
Sbjct: 5823 KDMVLNEKNRDIE-------EKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKEN 5875
Query: 1046 EGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYE--- 876
++ + + E + ++ + EE++ + DEL L+ E L+ E E
Sbjct: 5876 TLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEI 5935
Query: 875 -YHDYERKNVSGSRAEAMSVLISKSLGNGRANQREF-QNKEEDSSGVDLLKNKCTRLEFQ 702
D + ++ S + ++ + + +++ ++KEE ++ + +
Sbjct: 5936 IMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQS 5995
Query: 701 VQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLR 522
+ L + +M + + + ++ NKLE+M+ L +R +K+E R
Sbjct: 5996 RKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELE----------READEIRKIKEETQNER 6045
Query: 521 ---SEMKGELTPSR-SFKHREGSFIKEINIGDE 435
+M EL + SF H KE I D+
Sbjct: 6046 QSLEKMTEELKKEKESFTHLAEDTKKEQEILDK 6078
Score = 91.3 bits (225), Expect = 2e-15
Identities = 159/754 (21%), Positives = 300/754 (39%), Gaps = 22/754 (2%)
Frame = -1
Query: 2297 VSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQ 2118
++R E+ K+ L E F AL K E I +++ + EL + ++ E+Q
Sbjct: 2331 LNRELEKIKEKKTILAEEFEALDDKKEMI-------GKEMQRLGKMKAELQKEAEDTEKQ 2383
Query: 2117 RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDL 1938
R + ND ++ E+M Q E++++ +RD+ +L+ DR +EK+ DL
Sbjct: 2384 RRDIDNDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLESDRDTLEKERFDL 2443
Query: 1937 ENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQ-TEQNKQLELEIEKLYGS 1761
E K +++K L ++ ES Q IQ E K+ E+ +E+L +
Sbjct: 2444 EKTK------------------TEMKDLEKQLESQSRQHEIQLVEIQKEREI-LEQLKIN 2484
Query: 1760 LQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIE---DELART---- 1602
L ++ + +D EK + + + E Q ++EGI K + I+ DEL +T
Sbjct: 2485 LSKQKEDLEKERDCFEK--EKADISLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNV 2542
Query: 1601 -KEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVA 1425
KE+ + K++ D K+ I L D ++++ N RN+ +MV
Sbjct: 2543 VKELENNEL-QKQIIEDERDKIEQIKAELQKEAKDTEKQRQDI---ENDRRNNEEMV--- 2595
Query: 1424 LEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNA 1245
++Q+ K + ++ D I+ L+ Q L+ + KE ++
Sbjct: 2596 -IKLQNEKKD--------------IETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDL 2640
Query: 1244 KARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL 1065
K + LESQNR + +L +IQ+ER ++E LS + E+L+ E
Sbjct: 2641 KKTNTEMKDLEKQLESQNRQHEIQL-------AEIQKEREILEQLKLTLSKQKEDLEKE- 2692
Query: 1064 KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLR-NENAKLKNE 888
++ + E + L E L Q + E ++ + +DEL R N +L+N
Sbjct: 2693 RDCFEKEKADISLREELQEQS------EREGIGKTRVRIKKEMDELKQTRLNVVKELENN 2746
Query: 887 ALY-EYHDYERKNVSGSRAEAMSVL---------ISKSLGNGRANQREFQNKEED-SSGV 741
L + + ER + +AE I K N + QN+++D +
Sbjct: 2747 ELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETST 2806
Query: 740 DLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXI 561
D ++++ LE Q Q+L + E + + ++ ++ +++ L
Sbjct: 2807 DRIRDEEANLEVQKQRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQ 2866
Query: 560 RVRSLKKENTRLRSEMKGELTPSRS-FKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXX 384
+ R + ++ S+ K +L R F+ + ++ ++ + I
Sbjct: 2867 KEREILEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGID---------- 2916
Query: 383 XKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXX 204
+TRT QE+D L + + Q + +++ +++Q
Sbjct: 2917 ---NTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAEL--------- 2964
Query: 203 KWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKD 102
EK EL L E T+LKKD
Sbjct: 2965 ------KKEAEKTKLELQNERQNLEEAGTKLKKD 2992
Score = 90.9 bits (224), Expect = 2e-15
Identities = 148/726 (20%), Positives = 304/726 (41%), Gaps = 49/726 (6%)
Frame = -1
Query: 2276 EKQHTIELQENFNALRQ-KNEDICLKIEANNNLLEQKDNIIV-ELSHKLQENEEQRSALQ 2103
++ I+ ++ LR+ K + + +I ++ K +II E + ++N++ + L
Sbjct: 3311 KQNEMIDSEKKKMILREDKLQQMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMTELT 3370
Query: 2102 NDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKE 1923
+ VE TE+E L LL+ DV +L++ L + D +++ + LEN+KE
Sbjct: 3371 KQSEDVEIQMKEVLTEKELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKE 3430
Query: 1922 TVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQ--------NKQLELEIEKL- 1770
V K++ + E + +K ++ E ++ Q ++ N + EI +
Sbjct: 3431 -VLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIK 3489
Query: 1769 YGSLQMKQMENTL------LKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELA 1608
Y QMKQ ++ L +++ +++ +++ E+ +Q + KQ N+ D +
Sbjct: 3490 YQEKQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLKQSELDKQQTNMNDIIE 3549
Query: 1607 RTK-----------EVGRSATDMKKVNSDAGAKVSGILEMLLPMK--DDVFSLKEEVLGN 1467
K E+ +++K D + + E L MK VF ++ L
Sbjct: 3550 TMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVFEEEKNKLEQ 3609
Query: 1466 IN-SLRNDAQMVQVALEQMQDTKSEL---FAEAEIRAQEVLRLQAEVDAIQHILIELKRK 1299
+ L +A ++ E++Q+ + L E + + L + Q IL E+K
Sbjct: 3610 MKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVA 3669
Query: 1298 NQTLQDESQR---NAKEL-WNAKARLNNVMSKNINL---ESQNRSLKAELHLQAQKAFQI 1140
N++L E Q+ N +E+ N + +V +K NL E + L+AE+H Q + +I
Sbjct: 3670 NESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLREDELGQLQAEIHKQQR---EI 3726
Query: 1139 QEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFA 960
++E++ +ESE + VE+L+ ++ I L + E LD E+
Sbjct: 3727 EKEKSNIESERAAIIKIVEDLQHKI---------------ISLDRDAESLKLDREAFENE 3771
Query: 959 EEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQ 780
E L ++ EL +E K+K E HD + R E M+ I+K +
Sbjct: 3772 REVLKQMKTELERETDEIEKIKLET---QHDRQ-------RVEEMTAQITK-------ER 3814
Query: 779 REFQNKEEDSSGVDLLKNKCTR-LEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLS 603
+ N E+++ D++ N+ R +E +++ + +M E + ++ ++L ++++ L
Sbjct: 3815 DKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLE 3874
Query: 602 DMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTP 423
+ ++KE L + KH+E ++ + D+ T
Sbjct: 3875 KQ---------KENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTE 3925
Query: 422 L------IQXXXXXXXXXXXKIDTRTSETQEIDTLMDD-NRKYWNRVSHFTKQTQSLQNS 264
+ ++ ++D R SE + T M+D N K + ++
Sbjct: 3926 IQNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQ 3985
Query: 263 VQELQQ 246
QE+++
Sbjct: 3986 KQEMEK 3991
Score = 89.7 bits (221), Expect = 5e-15
Identities = 126/682 (18%), Positives = 290/682 (42%), Gaps = 37/682 (5%)
Frame = -1
Query: 2282 EEEKQHTI-ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
E++K++T+ E+Q+ + + NE+I ++ + EQ ++ K E ++ ++ +
Sbjct: 5870 EKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQ-------MNQKQDELDQLKTEI 5922
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
QN Q +E+ + +R + + + L ++ + + ++R ++K +++E QK
Sbjct: 5923 QNLQQELEKEKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQK 5982
Query: 1925 ETVSKELALSVSREQKLASDLKALSEKE---ESTKNQLLIQTEQNK-QLELEIEKLYGSL 1758
+ + KE + L DLK + ++ E KN+L EQ K +LE E +++
Sbjct: 5983 QEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKL----EQMKIELEREADEIRKIK 6038
Query: 1757 QMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSAT 1578
+ Q E L+ E++ + + + + +QE + K + E +A ++ +
Sbjct: 6039 EETQNERQSLEKMTEELKKEKESFTHLAEDTKKEQEILDKVKVANESLMADLQKEKSNLE 6098
Query: 1577 DMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEE---------------------VLGNIN 1461
+M++ S V E L +D+++ L+ E ++ N+
Sbjct: 6099 EMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQQREIEKEKINIESERAAIIKNVE 6158
Query: 1460 SLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQD 1281
L++ + E ++ + E E+ Q L+ E D I+ I +E + Q +++
Sbjct: 6159 DLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEE 6218
Query: 1280 ESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNV 1101
+ + K+ + K++ L +NR ++ +K IQ +++++E E +
Sbjct: 6219 MTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIE-------KKIKSIQSDKDMLEKEKHD 6271
Query: 1100 LS---SEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDE 930
L SE+ +K +L++ K+ ++ L + E + ++ + EE++ + DE
Sbjct: 6272 LEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDE 6331
Query: 929 LICLRNENAKLKNEALYEYH-------DYERKNVSGSRAEAMSVLISKSLGNGRANQREF 771
L L+ E L+ E E +R+ + + I +++ N R ++
Sbjct: 6332 LDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNER--KQLD 6389
Query: 770 QNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLS-DMX 594
++KEE ++ + ++ + L E +M + + + ++ NKLE+M+ L +
Sbjct: 6390 KDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREAD 6449
Query: 593 XXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQ 414
+ + L+K L+ E K + K RE + + E+ + +E +Q
Sbjct: 6450 DIRKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTK-REKNSLDEMKVANESSMADLQ 6508
Query: 413 XXXXXXXXXXXKIDTRTSETQE 348
I +T + ++
Sbjct: 6509 KEKSNLEEMKENISKQTEDIEK 6530
Score = 89.0 bits (219), Expect = 8e-15
Identities = 153/839 (18%), Positives = 338/839 (40%), Gaps = 89/839 (10%)
Frame = -1
Query: 2273 KQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDM 2094
K+ LQ+ + +E + E N E + +L + +E E+ + Q++
Sbjct: 3398 KKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHER 3457
Query: 2093 QSVEQMHAVSQTERE---ELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL----QDLE 1935
Q VE+M A Q +RE ++N + D+ + ++ + D+ ++ ++ Q+LE
Sbjct: 3458 QRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQELE 3517
Query: 1934 NQKETVSK---ELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEK--- 1773
+KE + K EL L S K +++ + E ++ + QL E+ ++ + EIEK
Sbjct: 3518 KEKEIIMKDRSELDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKH 3577
Query: 1772 --------LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIE- 1620
L L+M +++ + ++ K+ + L ++ E++ +E I + ++E
Sbjct: 3578 DFDQGRNSLDEDLKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEK 3637
Query: 1619 --DELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRND 1446
+EL R KE + K + ++ E L+ S EE+ NI+ D
Sbjct: 3638 MTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTED 3697
Query: 1445 AQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDA-----------IQHILIELKRK 1299
+ + L +D +L AE + +E+ + ++ +++ +QH +I L R
Sbjct: 3698 VKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKIISLDRD 3757
Query: 1298 NQTL-----------------QDESQRNAKELWNAKA---------------------RL 1233
++L + E +R E+ K ++
Sbjct: 3758 AESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITKERDKI 3817
Query: 1232 NNVMS----KNINLESQNRSLKAELHLQAQKAFQIQEERNVVESE-HNV--LSSEVENLK 1074
NN++ K++ L +NR ++ +K IQ +++++E E HN+ SE+ +K
Sbjct: 3818 NNLIEETNRKDMVLNEKNRDIE-------EKIKSIQSDKDMLEKEKHNLEKTRSELYKVK 3870
Query: 1073 SELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLK 894
+L++ K+ ++ L + E ++++ + EE++ + DEL L+ E L+
Sbjct: 3871 EDLEKQKENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEIQNLQ 3930
Query: 893 NEALYE----YHDYERKNVSGSRAEAMSVLISKSLGNGRANQREF--QNKEEDSSGVDLL 732
E E D ++ S + ++ + + N+R+ ++KEE +
Sbjct: 3931 QELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMK-NERKLLDKDKEEMEEQKQEM 3989
Query: 731 KNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVR 552
+ + ++ ++ L E +M + + + ++ NKLE+M+ L R
Sbjct: 3990 EKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQNER 4049
Query: 551 SLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKID 372
++ T+ + + +L + RE + E+ + ++ +Q I
Sbjct: 4050 QSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRILEEMRENI- 4108
Query: 371 TRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSV-QELQQXXXXXXXXXXXXXXKWG 195
+ +T++I+ + ++ + + + Q Q+ + E
Sbjct: 4109 --SKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQNMMT 4166
Query: 194 GIDMNS--IEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEE 24
+ S +E Q+KE+ L + LKKD++ + + + LK+D E
Sbjct: 4167 ELKKKSEDVEIQMKEILTEKELLENDSNLLKKDME---DLKQKLMSIERDSESLKLDRE 4222
Score = 87.8 bits (216), Expect = 2e-14
Identities = 151/751 (20%), Positives = 299/751 (39%), Gaps = 65/751 (8%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQ--KNEDICLK--------IEANNNLLEQKDNIIV 2154
K++++ EE ++ E+++ + + Q K+ D LK IE N LEQ +
Sbjct: 4682 KQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMK---I 4738
Query: 2153 ELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVD 1974
EL + E + + QN+ Q +E+M EEL ++ KE+ + +
Sbjct: 4739 ELEKEADEIRKIKEETQNERQRLEKM-------TEELKKE-----------KESFTHLAE 4780
Query: 1973 DRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQ 1794
D +K L ++ E++ +L S +++ ++ +E E K ++ ++ ++ +Q
Sbjct: 4781 DTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQ 4840
Query: 1793 LELEIEKLYGSLQMKQMENTL--------LKDGNEKIYDLCKLLAT--KSREVQGQQEGI 1644
L+ EI K G ++M++ N +KD K++ L + L + RE + +
Sbjct: 4841 LQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREV 4900
Query: 1643 LKQ---DI-----NIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFS- 1491
LKQ D+ IE T+ + +M K++ ++E KD V +
Sbjct: 4901 LKQIKTDLKRKAEEIEKIKLETQHDRQRVEEMTAQIQKERDKINNLIEE-TNRKDMVLNE 4959
Query: 1490 LKEEVLGNINSLRNDAQMVQVALEQMQDTKSELF-AEAEIRAQEVLRL------------ 1350
+K E+ I ++ +D M++ ++ T+S+L A+ + Q ++L
Sbjct: 4960 IKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEK 5019
Query: 1349 -----QAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRS 1185
E+ I+H ++K+K QDE + E+ N + L + SQ
Sbjct: 5020 MNEKFTIEIHDIKHQEEQMKQK----QDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDL 5075
Query: 1184 LKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-KESKDLEGYFLRLFEILLG 1008
++EL Q I E + + E E K E+ KE D + L E L
Sbjct: 5076 RQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLKM 5135
Query: 1007 QHVEVASLDIESCRFAEEKL--------MRILDELICLRNENAKLKNEALYEYHDYERKN 852
++ L+ E + + K+ +R + E I +N + EAL E ER++
Sbjct: 5136 MKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKE----ERED 5191
Query: 851 VSGSRAEAMSVLISKSLGNG-------RANQREFQNKEEDSSGVDLLKNKCTRLEFQVQK 693
++ + VL + N R + +E S + ++NK L + +
Sbjct: 5192 LAEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDE 5251
Query: 692 LSE-KAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSE 516
L + +AE+ + + ++ N E + D+ SLK + +E
Sbjct: 5252 LRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENE 5311
Query: 515 MKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTL 336
K L ++ RE I++I + + D ++ +I+ ET D +
Sbjct: 5312 -KEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMV 5370
Query: 335 MDD-NRKYWNRVSHFTKQTQSLQNSVQELQQ 246
+++ NR ++ L+ +L++
Sbjct: 5371 LNEKNRDIEEKIKSIQSDKDMLEKEKHDLEK 5401
Score = 85.9 bits (211), Expect = 7e-14
Identities = 124/662 (18%), Positives = 287/662 (43%), Gaps = 38/662 (5%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIE----ANNNLLEQKDNIIVELSHKL 2136
+E ++++++ L E + E++ ++ E AN + + ++ +++EL +
Sbjct: 2983 EEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIELKKTV 3042
Query: 2135 QENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFME 1956
+ + L+N + + + V Q E + L LL+ ++ + + + E
Sbjct: 3043 TDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQLRLRE 3102
Query: 1955 KQLQDLE------------NQKETVSKELAL-----SVSREQKLASDLKALSEKE----E 1839
+L+ L+ N+K ++++ L + R Q+ + + + K+ E
Sbjct: 3103 VELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYASKDRANLE 3162
Query: 1838 STKNQLLIQTEQNKQLELEIEKLYGSLQMK-QMENTLLKDGNEKIYDLCKLLATKSREVQ 1662
K++++ Q Q+++E+ K G ++ + QM NT K+ ++K L + +E++
Sbjct: 3163 KEKSEMI---AQKHQMDIELNKERGLIEERTQMLNTYEKEMDQK----RTALEVEMKELK 3215
Query: 1661 GQQEGILKQDINIEDELARTK-EVGRSATDMKKVNS---DAGAKVSGILEMLLPMKDDVF 1494
++ I ++ +++L + K E+ R A D+KK+ + + + E L KDD+
Sbjct: 3216 YHKQAIQEE----KNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLA 3271
Query: 1493 SLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILI 1314
L E+ + R D +M + + D + E ++R + + + +D+ + +I
Sbjct: 3272 HLAED------TKRKDDEMKVLHESALADIQKEKCNLEQMR-ESMFKQNEMIDSEKKKMI 3324
Query: 1313 ELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKA-FQIQ 1137
+ K Q +Q E R E+ K+ + N + + +N+ L EL Q++ Q++
Sbjct: 3325 LREDKLQQMQAEINRQQTEMDTKKSIIEN---ERAAMTKKNQDLMTELTKQSEDVEIQMK 3381
Query: 1136 E---ERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCR 966
E E+ ++ES+ +L +VENL+ +L +++ E D E
Sbjct: 3382 EVLTEKELLESDRKLLKKDVENLQQKL---------------LIIESDSESLKQDRELLE 3426
Query: 965 FAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSR----AEAMSVLISKSLG 798
+E L ++ +L E K+K E +E E + + M+ I++ +
Sbjct: 3427 NEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIH 3486
Query: 797 NGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEM 618
+ + +++ + K+++ +D LK + L+ Q+L ++ E+ E ++L++
Sbjct: 3487 DIKYQEKQMKQKQDE---LDQLKTEIQNLQ---QELEKEKEIIMKDRSELDLKQSELDKQ 3540
Query: 617 QQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGD 438
Q ++D+ + ++K E +L + + R + + F + N D
Sbjct: 3541 QTNMNDI-------------IETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLD 3587
Query: 437 ED 432
ED
Sbjct: 3588 ED 3589
Score = 85.9 bits (211), Expect = 7e-14
Identities = 148/799 (18%), Positives = 321/799 (40%), Gaps = 47/799 (5%)
Frame = -1
Query: 2279 EEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQ------ 2118
E+++H +E + A ++N + +IE ++ + K NI E+ H+++ EEQ
Sbjct: 4309 EKERHNLEKTRSELARAKENLETQREIE-RKDIEKMKKNISREM-HEIKHQEEQMKQKQD 4366
Query: 2117 -----RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK 1953
++ +QN Q +E+ + R +L+ + L ++ + + ++R ++K
Sbjct: 4367 ELDQLKTEIQNLQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDK 4426
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALS------EKEESTKNQLLIQTEQNKQL 1791
++ E QK+ + KE + L DLK + E+E+S Q+ I+ E+
Sbjct: 4427 DKEETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVIEEEKSKLKQMKIELEREAD- 4485
Query: 1790 ELEIEKLYGSLQ------------MKQMENTLLKDGNEK--IYDLCKL-----LATKSRE 1668
EI K+ Q +K+ L +D K + D K+ LA RE
Sbjct: 4486 --EIRKVKEETQNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRE 4543
Query: 1667 ---VQGQQEGILKQDINIEDE----LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPM 1509
+Q +E I KQ ++E++ R +++ + ++ K S+ + S I +
Sbjct: 4544 RSNLQEMRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNIERERAAI 4603
Query: 1508 KDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAI 1329
DV L+ +++ SL DA+ +++ E ++ K EL Q L+ E D I
Sbjct: 4604 IKDVEDLQSKII----SLDRDAESLKLDREAFENEKEEL-------KQMKTELEREADEI 4652
Query: 1328 QHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKA 1149
+ I +E + + Q +++ + + + N + +LN ++ Q + ++ E H Q
Sbjct: 4653 EKIKLETQHERQRVEEMTADFMETMNNERKQLN---KNKEEMQEQKQEMEKERHDMDQSR 4709
Query: 1148 FQIQEERNVVESEHNVLSSE---VENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDI 978
+ + +++ + V+ E +E +K EL++ D E+ +
Sbjct: 4710 KSLDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEAD-----------------EIRKIK- 4751
Query: 977 ESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLG 798
E + ++L ++ +EL + L + E ++ V+ E++ + K
Sbjct: 4752 EETQNERQRLEKMTEELKKEKESFTHLAEDTKTEKKILDKMKVAN---ESLMADLQKEKS 4808
Query: 797 NGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEM 618
N + + EDS + K K E ++++L +AE+ + + + +N E
Sbjct: 4809 NLEEMRENISKQTEDS---EKEKEKIRLREDELEQL--QAEIHKQQGEIKMEKSNNESER 4863
Query: 617 QQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGD 438
+ D+ + SLK + +E + L ++ R+ I++I +
Sbjct: 4864 AAIIKDVKDLQHKMFSLDRDLESLKLDREAFENE-REVLKQIKTDLKRKAEEIEKIKLET 4922
Query: 437 EDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDD-NRKYWNRVSHFTKQTQSLQNSV 261
+ D ++ KI+ ET D ++++ + ++ L+
Sbjct: 4923 QHDRQRVEEMTAQIQKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEK 4982
Query: 260 QELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAW 81
+L++ ++EKQ K ++L E + K +
Sbjct: 4983 HDLEKTRSKLLRA------------KENLEKQRK------IKLAEIQKEREDLEKMNEKF 5024
Query: 80 ANSMHDLNGQEQKLKVDEE 24
+HD+ QE+++K ++
Sbjct: 5025 TIEIHDIKHQEEQMKQKQD 5043
Score = 85.1 bits (209), Expect = 1e-13
Identities = 119/600 (19%), Positives = 256/600 (42%), Gaps = 34/600 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEE 2121
E+S++ EE + L++ NAL+++ E + +I+ N +L D I V NE
Sbjct: 6713 EISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVL---DKIKV-------ANES 6762
Query: 2120 QRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDD----RAFMEK 1953
+ LQ + + +E+M RE +++Q+ +D+ + KE + D+ + ++K
Sbjct: 6763 TLADLQKEKRILEEM-------RENISKQI----EDIENEKEKSKLREDELKKLQTEVQK 6811
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTE----QNKQLEL 1785
Q +++ +K + E A + +Q + ++LK SE E ++L + E L+
Sbjct: 6812 QQSEIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKK 6871
Query: 1784 EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 1605
++E L L + ++ LK E + + + ++Q Q + I K + E R
Sbjct: 6872 DVEDLQQKLMSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQR 6931
Query: 1604 TKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVA 1425
+E A++ E + + +++ ++ + + +R + + ++
Sbjct: 6932 VEE--------------KTAQIQKEREEINTLVEEIKKKRDIIDESYTEIRKEKEAIESD 6977
Query: 1424 LEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNA 1245
++ KS+ F + + + +Q + +A++ + E+ R L+DE KE+ A
Sbjct: 6978 RSDLEKAKSQTFKQNKNIEIALAEIQQKRNALEKMSKEISRDRMKLEDEK----KEIQLA 7033
Query: 1244 KARLNNV-------------MSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHN 1104
+ L + + I ES + +AE+ LQ + + + R S+ +
Sbjct: 7034 REELERMHGDMQRQQEAKDHLLSGITDESLLKKSEAEIVLQPSQVDKAKPARKTEISDSD 7093
Query: 1103 -----VLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRI 939
V +LK LK+ + E L + +L Q ++ E+KL I
Sbjct: 7094 KQPVFVQQMPEMDLKDALKKDFESEKLDLPKVKDVLPQDQQMK---------LEQKL--I 7142
Query: 938 LDELICLRNENAKLKNEA-LYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQR---EF 771
DE+ L+ A+L+ EA E + +N + + L + N R N+ +
Sbjct: 7143 EDEMDKLKQMRAELQKEADQIEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINIQK 7202
Query: 770 QNKEEDSSGVDLLKNKCTRLEFQV----QKLSEKAEMFETKSREAQQMANKLEEMQQTLS 603
N+++ ++ + K R++ ++ ++L+++ E + E Q+ LEEM+ +S
Sbjct: 7203 VNQQKQATAFQMEKTDFERIKTEIDQANKELADQQEKNKKTITEMQKERETLEEMRANIS 7262
Score = 85.1 bits (209), Expect = 1e-13
Identities = 120/621 (19%), Positives = 270/621 (43%), Gaps = 60/621 (9%)
Frame = -1
Query: 2279 EEKQH-TIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIV----ELSHKLQENEEQR 2115
++K+H T E ++ + ++ KI+ LE++ ++ L+ L+E + Q+
Sbjct: 9930 DKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQIEAENLNKVLEEIKRQQ 9989
Query: 2114 SALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLE 1935
L+ ++ M + REE R+ + + + + + A + +R ++KQ Q+L+
Sbjct: 9990 EKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQKQELQ 10049
Query: 1934 NQKETVSKELALSVSREQKLASDLKALSEKE---ESTKNQLLIQTEQNKQLELEIEKLYG 1764
Q + + + ++ + + ++L E++ E N++L Q + ++ + ++ K +
Sbjct: 10050 KQADDLDMRM---IAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWN 10106
Query: 1763 SLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRS 1584
L + Q E +++ N+ + ++ E+ G++ I K+ +E+ L + +
Sbjct: 10107 KLDVLQNE---MQNENKAMEEI-------KYELDGKRNEINKEQQRLEESL---RAINEE 10153
Query: 1583 ATDMKKVNSDAGAKVSGILEM----------LLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
D++ + +D + I EM L +K ++ K E+ L ND M+
Sbjct: 10154 KGDLEIMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMI 10213
Query: 1433 Q--------------VALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIEL---- 1308
+ +QM+D +SEL + + E +++ + ++ ++ E+
Sbjct: 10214 EKERNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQR 10273
Query: 1307 ---KRKNQTLQDESQRNAKE---LWNAKARLNNVMSKNINLE----SQNRSLK-AELHLQ 1161
K K + L E Q E L + L N + N+E ++ +LK E HLQ
Sbjct: 10274 NDFKLKKEELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQ 10333
Query: 1160 AQK--AFQIQEERNVVESEHNVLSSEVENLKSELKESKD-LEGYFLRLFEILLGQHVEVA 990
K I EE + + + +S+ + K ELK KD LE + +
Sbjct: 10334 RDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRID 10393
Query: 989 SLDIESCRFAEEKL---MRILDELICLRNENAK---LKNEALYEYHDYERKNVSGSRAEA 828
D + + EE L ++ +E CL N K +K +A E+H+ +K + +
Sbjct: 10394 EFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQK-IEELQTLQ 10452
Query: 827 MSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREA 648
++ K + + + ++ D +L++ K T ++ + +KL++ +M E + +
Sbjct: 10453 EQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREK-TEVDHEQKKLNDDIKMIEQEKEDL 10511
Query: 647 QQMANKL----EEMQQTLSDM 597
++M +++ +EM++ S++
Sbjct: 10512 EKMKSEIMTQKQEMEKERSEL 10532
Score = 85.1 bits (209), Expect = 1e-13
Identities = 116/634 (18%), Positives = 264/634 (41%), Gaps = 36/634 (5%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
K S + ++ +Q E E N +RQ + C IE + ++++ + E H++Q +
Sbjct: 11905 KMKSEIMKQRQQMEEERSELENKIRQTYIEKC-DIENSKEIVQKLMVEVEEQKHEIQFQK 11963
Query: 2123 EQ------------------RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLK 1998
E+ +S LQN+ + ++ ++ V + ERE L L + +K
Sbjct: 11964 EELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMK 12023
Query: 1997 EALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLL 1818
+ +EK + QK+ + + L +++ K L ++ + Q+
Sbjct: 12024 SITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVS 12083
Query: 1817 IQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILK 1638
Q E++ E E+++ SL+ + +K E +E + ++E +
Sbjct: 12084 KQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEP--------EEIKKEKEKEEE---E 12132
Query: 1637 QDINIEDELARTKEVGRSATDMKKVNSDAG---AKVSGILEMLLPMKDDVFSLKEEVLGN 1467
Q++ ++ E+ R KE+ + + +++V S+ K++ +M+ K+D+ +K E++
Sbjct: 12133 QEMRVKVEMER-KEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQ 12191
Query: 1466 INSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTL 1287
+ + + ++Q K ++ EI + ++ ++ + IQ EL + Q +
Sbjct: 12192 RQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKI 12251
Query: 1286 QDESQ---RNAKELWNAKARLNNVMSKNINLESQN-RSLKAELHLQAQKAFQIQEERNVV 1119
DE +N E N R+ M + I E + + ++ L + ++ + EE
Sbjct: 12252 ADEQDLLIQNKIEQQNENERIKE-MDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRR 12310
Query: 1118 ESEHNVLSSEVENLKSELKESKDL---EGYFLRLFEILLGQHVE--------VASLDIES 972
+ + +S+++ K +L +DL E + L Q ++ + + +E
Sbjct: 12311 KEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEE 12370
Query: 971 CRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNG 792
+EKL + + E + E + + E D ++N E M L+ K +
Sbjct: 12371 KTEMDEKLQQAIKEYESIIEETNRKRTELEEIEVDQSQQN---KNVETMKDLLEKERKDT 12427
Query: 791 RANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQ 612
+ E Q K+ D + ++++ + E + L E+ ++ E K+ E + + LE+ ++
Sbjct: 12428 EKEREELQ-KQADDLEMQMIEHG-DKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKE 12485
Query: 611 TLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK 510
DM +++ K E ++ E++
Sbjct: 12486 ---DMMKKWNELDGLQKEIQNQKNEMEEIKCELE 12516
Score = 84.3 bits (207), Expect = 2e-13
Identities = 147/702 (20%), Positives = 294/702 (41%), Gaps = 78/702 (11%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQEN---FNALRQKNEDICLKIEANNNLLE------QKDNIIVE 2151
+EV +E +Q T +L+E+ F+ ++KN I +I+ ++ LE K+ I E
Sbjct: 1957 QEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTIFE 2016
Query: 2150 LSHK---LQENE-----EQRSALQNDMQ----SVEQMHAVSQTER--------------- 2052
L + L+ENE +Q LQN ++ VEQM A +R
Sbjct: 2017 LEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTARGRETT 2076
Query: 2051 --EELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQK 1878
EE +++ LR++ ++++ + + E +++ LE + E + K+ + +E +
Sbjct: 2077 ALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAM-KKYKEKLDKEYE 2135
Query: 1877 LASDLKALSEKE-ESTKNQLLIQTE--QNKQLELEIEK--LYGSLQMKQMENTLL-KDGN 1716
+ L EKE + + +L I+ E + K+ ELEI+K +Y M + + ++ K
Sbjct: 2136 DLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKT 2195
Query: 1715 EKIYDLCKLLATKSREVQGQQEGILKQDINI-EDELARTKEVGRSATDMKKVN---SDAG 1548
+++ ++ K + EV+ Q+ +++ ++ I ++E KE R + N S
Sbjct: 2196 DELDEVRKKINADLSEVEKQKSALVQMNLKISQEESYVKKEKDRLKLQENEQNMQMSQLN 2255
Query: 1547 AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRA 1368
AK + + E M+ L E V+ + + + + + +MQ+ A ++
Sbjct: 2256 AKQNELDERQAEMEKQKREL-ENVMDRLEKEKVEITKEKQRVNEMQNEVKRKNASVDLIK 2314
Query: 1367 QEVLRLQAEVDAIQHI----LIELKRKN-------QTLQDESQRNAKELWNAKARLNNVM 1221
QEVLR Q ++ + I L ++K K + L D+ + KE+ +
Sbjct: 2315 QEVLREQDHIENSREILNRELEKIKEKKTILAEEFEALDDKKEMIGKEMQRLGKMKAELQ 2374
Query: 1220 SKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-------- 1065
+ + E Q R + + + ++Q E+ +E+ + + E NL+ +
Sbjct: 2375 KEAEDTEKQRRDIDNDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLESDRD 2434
Query: 1064 ---KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLK 894
KE DLE + + L + +E S E +K IL++ L+ +K K
Sbjct: 2435 TLEKERFDLEKTKTEMKD--LEKQLESQSRQHEIQLVEIQKEREILEQ---LKINLSKQK 2489
Query: 893 NEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEE-DSSGVDLLKNKCT 717
+ E +E++ S E + K G + R Q +E + + ++++K +
Sbjct: 2490 EDLEKERDCFEKEKADISLREELEEQSEKE-GIDKTRVRIKQEMDELEQTRLNVVK-ELE 2547
Query: 716 RLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTL-SDMXXXXXXXXXXXIRVRSLKK 540
E Q Q + ++ + E E Q+ A E+ +Q + +D + ++
Sbjct: 2548 NNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIET 2607
Query: 539 ENTRLRSE------MKGELTPSRSFKHREGSFIKEINIGDED 432
R+R E +K L R +E +K+ N +D
Sbjct: 2608 STDRIRDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEMKD 2649
Score = 84.3 bits (207), Expect = 2e-13
Identities = 158/788 (20%), Positives = 326/788 (41%), Gaps = 59/788 (7%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNII----VELSHKLQENEEQR 2115
EE+KQ + ++N + R+ ++ K++ + E++ N + +EL + E + +
Sbjct: 5523 EEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIK 5582
Query: 2114 SALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLE 1935
QN Q +E+M EEL R+ KE+L+ +D +K L +++
Sbjct: 5583 EETQNKRQRLEKM-------TEELIRE-----------KESLAHLAEDTKTEKKILDEMK 5624
Query: 1934 NQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQ 1755
E+ +L S +++ ++ L E ++ K + ++ ++ K+L+ E++K +
Sbjct: 5625 VANESSMADLQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKID 5684
Query: 1754 MKQ--MENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSA 1581
M++ +E+ EK ++ L KS +V+ Q + IL E EL
Sbjct: 5685 MEKTNIESERAAMIREK-QNMMTELKKKSEDVEIQMKEIL-----TEKELLH-------- 5730
Query: 1580 TDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQM---VQVALEQMQ 1410
D K + D V + + L+ ++ D LK + N QM +Q+ ++++
Sbjct: 5731 NDRKLLTRD----VENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEIE 5786
Query: 1409 DTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLN 1230
K E + + + ++Q E D I +++ E RK+ L ++++ +++ + ++ +
Sbjct: 5787 KIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKD 5846
Query: 1229 NVMSKNINLESQNRSL-KAELHLQAQK---AFQIQEERNVVE------------------ 1116
+ + NLE L K + L+ QK +IQ+ER VE
Sbjct: 5847 MLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEE 5906
Query: 1115 ------SEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAE- 957
E + L +E++NL+ EL++ K++ F++ + LD + +
Sbjct: 5907 QMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQFDL------RQSELDKQQTNMNDI 5960
Query: 956 -EKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQ 780
E + +L + E + K E E HD+++ S + + + + K + N+
Sbjct: 5961 METMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDK-DLKMMKLQKQVFEEEKNK 6019
Query: 779 REFQNKEEDSSGVDLLK------NKCTRLEFQVQKLSEKAEMF---ETKSREAQQMANKL 627
E E + ++ K N+ LE ++L ++ E F +++ Q++ +K+
Sbjct: 6020 LEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFTHLAEDTKKEQEILDKV 6079
Query: 626 E--------EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHRE 471
+ ++Q+ S++ V + KKEN RLR + +L + RE
Sbjct: 6080 KVANESLMADLQKEKSNLEEMRENISKQTEDVEN-KKENLRLREDELWQLQAEIYKQQRE 6138
Query: 470 GSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFT 291
I++ I E + I +D R SE+ ++D R+ +
Sbjct: 6139 ---IEKEKINIESERAAIIKNVEDLQHKIISLD-RDSESLKLD------REAFENEREVL 6188
Query: 290 KQTQS-LQNSVQELQQXXXXXXXXXXXXXXKWGGI--DMNSIEKQLKELNIHVMQLVEHN 120
KQ ++ L+ E+++ I D + I ++E N M L E N
Sbjct: 6189 KQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKN 6248
Query: 119 TRLKKDVK 96
++K +K
Sbjct: 6249 RDIEKKIK 6256
Score = 84.0 bits (206), Expect = 3e-13
Identities = 140/786 (17%), Positives = 327/786 (41%), Gaps = 26/786 (3%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQ-----ENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHK 2139
+E + EE K IE++ E ++K E+ ++ + E+ D I +L
Sbjct: 11542 EEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKK-EELDQIKSQLERV 11600
Query: 2138 LQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFM 1959
E + ++ L +D + +EQ + + E+ +Q + ++ + L + +R
Sbjct: 11601 RSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLER--- 11657
Query: 1958 EKQLQDLENQKETVSKELA--------LSVSREQKLASDLKALSEKEESTKNQLLIQTEQ 1803
D+EN KE V K + + + +E+ K E+ +N+ +Q E
Sbjct: 11658 ----HDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNEN 11713
Query: 1802 NKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQD--- 1632
+ E++ E +K+ME L K+ E + + + +++ + KQ+
Sbjct: 11714 ERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDL 11773
Query: 1631 INIEDELARTK-EVGRSATDMKKVNSDAGAKVSGILEMLL----PMKDDVFSLKEEVLGN 1467
+N D L + + E+ T +++ + A+VS E L M+++ SL+E +
Sbjct: 11774 MNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKI-K 11832
Query: 1466 INSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTL 1287
I ++ + ++ E+ ++ + + A+ E++ +E+ +++++++ ++ E+ + + L
Sbjct: 11833 IIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRS---EIDHEQKKL 11889
Query: 1286 QDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEH 1107
D+ + +E + + + +M + +E + L+ ++ + I+ + +V+
Sbjct: 11890 NDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQK-- 11947
Query: 1106 NVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL 927
L EVE K E++ K+ LDIE + A+E+ + I ++
Sbjct: 11948 --LMVEVEEQKHEIQFQKE--------------------ELDIERQKIADEQDLLIQNKS 11985
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSS 747
L+NEN ++KN + E ER+ + + M + K ++ E + ++ED
Sbjct: 11986 E-LQNENERIKN--INEVIKKERETL-----KEMEAYLEKEKEEMKSITEETRRQKED-- 12035
Query: 746 GVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXX 567
L+ T + Q Q L + ++ E +E +++ +K +++QQ + +
Sbjct: 12036 ----LEKMSTHINEQKQDLRSQRDLLE---QEREEINHKWKQLQQRIDEFDAQVSKQKEE 12088
Query: 566 XIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXX 387
+ KE+ + E K + ++ E IK+ +E++ Q
Sbjct: 12089 DLPKEKEMKEDRKSLEETKANILEMKT--KAEPEEIKKEKEKEEEE----QEMRVKVEME 12142
Query: 386 XXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQ-TQSLQNSVQELQQXXXXXXXXXXXX 210
+I+ S+ + + + MD +K N +Q + L+ E+ +
Sbjct: 12143 RKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMK------------ 12190
Query: 209 XXKWGGIDMNSIEKQLKELNIHVMQ--LVEHNTRLKKDV--KFGFAWANSMHDLNGQEQK 42
+E++ EL+ + Q L +H+ K++ K H++ Q+++
Sbjct: 12191 -------QRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEE 12243
Query: 41 LKVDEE 24
L ++ +
Sbjct: 12244 LDIERQ 12249
Score = 83.6 bits (205), Expect = 4e-13
Identities = 153/813 (18%), Positives = 320/813 (39%), Gaps = 62/813 (7%)
Frame = -1
Query: 2276 EKQHTI---ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
EKQ I E+Q+ L + NE ++I + EQ + K E ++ ++ +
Sbjct: 5000 EKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQ-------MKQKQDELDQLKTEI 5052
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
QN Q +E+ + +R +L+ + L ++ + + ++R ++K ++ E QK
Sbjct: 5053 QNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQK 5112
Query: 1925 ETVSKELALSVSREQKLASDLKALS------EKEESTKNQLLIQTEQN----KQLELEI- 1779
+ + KE + L DLK + E E+S Q+ I+ E+ ++++ EI
Sbjct: 5113 QEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQ 5172
Query: 1778 ------EKLYGSLQMKQMENTLLKDGNEKIYD---------LCKLLATKSREVQGQQEGI 1644
EK+ +L+ ++ + N ++ D L +L KS ++ +E I
Sbjct: 5173 NERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKS-NLEEMRENI 5231
Query: 1643 LKQDINIEDE----LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEV 1476
KQ ++E++ R E+ + ++ K + + I + DV L+ ++
Sbjct: 5232 SKQTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKI 5291
Query: 1475 LGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKN 1296
+ L DA+ +++ E ++ E E+ Q L+ E D I+ I +E +
Sbjct: 5292 I----CLDRDAESLKLDREAFEN-------EKEVLKQMKTELEREADEIEKIKLETQHDR 5340
Query: 1295 QTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVE 1116
Q +++ + + K+ + K++ L +NR ++ +K IQ +++++E
Sbjct: 5341 QRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIE-------EKIKSIQSDKDMLE 5393
Query: 1115 SEHNVLS---SEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLM 945
E + L SE+ +K +L++ K+ ++ L + E + ++ + EE++
Sbjct: 5394 KEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMN 5453
Query: 944 RILDELICLRNENAKLKNEALYE----YHDYERKNVSGSRAEAMSVLISKSLGNGRANQR 777
+ DEL L+ E L+ E E D + ++ S + ++ + + ++
Sbjct: 5454 QKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERK 5513
Query: 776 EF--------QNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLE- 624
+ + K+E D + L+ +K+ + +MFE + + +QM +LE
Sbjct: 5514 QLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELER 5573
Query: 623 -------------EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSF 483
+Q L M + K ++ EMK S +
Sbjct: 5574 EADEISKIKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMAD 5633
Query: 482 KHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRV 303
RE S ++E+ I ++ +E Q+ + +D + N
Sbjct: 5634 LQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKT--NIE 5691
Query: 302 SHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEH 123
S + QN + EL++ +E Q+KE+ L
Sbjct: 5692 SERAAMIREKQNMMTELKK-------------------KSEDVEIQMKEILTEKELLHND 5732
Query: 122 NTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEE 24
L +DV+ + DL ++LK+D E
Sbjct: 5733 RKLLTRDVE---NLQQKLIDLERDSKRLKLDRE 5762
Score = 83.6 bits (205), Expect = 4e-13
Identities = 128/620 (20%), Positives = 275/620 (44%), Gaps = 63/620 (10%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLE-QKDNIIVELSHKLQEN 2127
+E S L ++ KQ +E + N+ ++ E + +++E + ++ QK+ + +E E
Sbjct: 12197 EERSELDKKIKQTDLEKHDIENS-KEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQ 12255
Query: 2126 E---EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFME 1956
+ + + QN+ + +++M + ERE L V L+ + ++ + + +E
Sbjct: 12256 DLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLE 12315
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSEK--EESTKNQLLI------QTEQN 1800
K D+ QK+ + + L +++ L L ++ E T + +L+ +TE +
Sbjct: 12316 KMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMD 12375
Query: 1799 KQLELEIEKLYGSLQMKQMENTLLKD-------GNEKIYDLCKLLATKSREVQGQQEGIL 1641
++L+ I++ ++ + T L++ N+ + + LL + ++ + ++E +
Sbjct: 12376 EKLQQAIKEYESIIEETNRKRTELEEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQ 12435
Query: 1640 KQDINIEDELAR---TKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLG 1470
KQ ++E ++ +E+ + + D +K + A +L +DD+ KE+++
Sbjct: 12436 KQADDLEMQMIEHGDKEEMSKRSLDEEKKLLEQKANE------ILRQRDDLEKEKEDMMK 12489
Query: 1469 NINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAI------------- 1329
N L + +Q +M++ K EL + +E RL+ ++ +
Sbjct: 12490 KWNELDGLQKEIQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLEIVRVD 12549
Query: 1328 ----QHILIELKRKNQTLQDE-SQRNAKELWNAKARLNNVMSKNI------NLESQNRSL 1182
Q + E++ K + +DE Q AK L + K N SK++ +E +L
Sbjct: 12550 YEKHQQQIEEMRVKTKMERDELDQLMAKMLMDRK---ENERSKDMIGLLKKEMEQTKFNL 12606
Query: 1181 KA---ELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILL 1011
A EL L+ QK +++ + ++E +SEV+ LK + E KD + + E L
Sbjct: 12607 DAQEEELKLEKQKIQNEKKDLEMFKAEIKREASEVKTLKEQQLE-KDTKAFEALKEEHLP 12665
Query: 1010 GQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKL-KNEALYEYHDYERKNVSGSR- 837
GQ V+ + E + E K RIL E + E +L +N+ + E+ + +
Sbjct: 12666 GQFVQQKGGEFERIQIDEVK--RILSE---IHKEKKELERNKQILEHQREALLEIKSKQP 12720
Query: 836 AEAMSVLISKS---------LGNGRANQREFQNKEEDSSGVDLLKNKCTRL---EFQVQK 693
+E + V++ S + + A+Q E K D++K T + E+++ K
Sbjct: 12721 SERLDVILVSSATQTSDLEDIPDVSASQGETVEKH-----TDIIKEYTTSIPKEEYEIDK 12775
Query: 692 LSEKAEMFETKSREAQQMAN 633
L ++ + +RE +MA+
Sbjct: 12776 LKQQGDKKLKSTREDTKMAD 12795
Score = 83.6 bits (205), Expect = 4e-13
Identities = 137/665 (20%), Positives = 282/665 (42%), Gaps = 98/665 (14%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNI---IVELSHKLQE 2130
E+ +L ++ ++ EL++ L+++ + KI+A Q D I I L + +E
Sbjct: 13149 EIQKLRKQYEKEKCELEQIKPDLQKREPE---KIDAE----VQHDEIHGGIDSLKEEREE 13201
Query: 2129 NEEQRSALQNDMQSVEQMHAVSQTEREELNR------QLVL----------LRDDVNHLK 1998
E+ ++ LQN ++ E M + + E++EL + Q+ + L+D++ ++
Sbjct: 13202 IEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIE 13261
Query: 1997 EALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKA-----LSEKEEST 1833
L + + ++E+ ++L +K + + + +L +K +S+ EE
Sbjct: 13262 AILKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKMEERE 13321
Query: 1832 KNQLLIQ------TEQNKQLELEIEKLYG-SLQMKQMENTLLKDGNEKIYDLCKLLATKS 1674
+ I+ E++++++ E E+L ++K+ L + NE + K
Sbjct: 13322 AERKTIERVMDEMAEEHEKIKKEREELVNMEEEIKKQRRVLEESMNE--------MTKKK 13373
Query: 1673 REVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGIL----EMLLPMK 1506
E+Q ++ + KQ +ED +A S D+ S + IL E + MK
Sbjct: 13374 SELQHERSELYKQKQQLEDMIA-----SESKRDVDTERSRQDKEDEQILKREREEIADMK 13428
Query: 1505 DDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSE--------LFAEAEIRA------ 1368
D + KE+V + + + ++ Q+ D K E L+ + EI+
Sbjct: 13429 DQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEIQVKTNALE 13488
Query: 1367 ---QEVLRLQAEVDA--IQH---------ILIELKRKNQTLQDESQRNAKELWNAKARL- 1233
Q++ + + V+A IQH ++ E KRK + + E QR +++ + K RL
Sbjct: 13489 KMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFEDIESVKVRLV 13548
Query: 1232 ---NNVMSKNINLESQNRSLKAELHLQAQKAF-----QIQEERNVVESEHNVLSSEVENL 1077
N + N L++++ L+ L + QK F ++Q ER +E + L + L
Sbjct: 13549 TESNQIDKMNSELKTRSEELE-NLIKKQQKEFETKENEMQRERKALEKMNAELERKSTEL 13607
Query: 1076 KSELKE----SKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEK---------LMRIL 936
K+++++ DL+ + E+ E + L E + ++K + +
Sbjct: 13608 KNKIEKVTVWEADLQKEKNKTEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEM 13667
Query: 935 DELICLRNENAKLKNEAL----YEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQ 768
+ L CLRNE K L E H+ ++ ++E S+ K ++ E +
Sbjct: 13668 ENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTE-IQSEKESIEEEKKTLKQLKDENESK 13726
Query: 767 NKEEDSSGVDLLKNKCTRLEFQVQK---------LSEKAEMFETKSREAQQMANKLEEMQ 615
+ D++ + K +L Q +K L KAE + + R+A Q+ +++ +
Sbjct: 13727 RTQLDNT---IEKMNMDKLSIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDA 13783
Query: 614 QTLSD 600
+ L D
Sbjct: 13784 KILDD 13788
Score = 81.6 bits (200), Expect = 1e-12
Identities = 148/839 (17%), Positives = 336/839 (40%), Gaps = 86/839 (10%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNII----VELSHKLQENEEQR 2115
EE+K+ + + +F+ R ++ ++ + E++ N + +EL + E + +
Sbjct: 3566 EEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIK 3625
Query: 2114 SALQNDMQSVEQM------------HAVSQTER--------------------------E 2049
+QN+ QS+E+M H T++ E
Sbjct: 3626 EEIQNERQSLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEKSNFE 3685
Query: 2048 ELNRQLVLLRDDVNHLKEALSMAVDD----RAFMEKQLQDLENQKETVSKELALSVSREQ 1881
E+ + +DV + KE L + D+ +A + KQ +++E +K + E A + +
Sbjct: 3686 EMRENISKQTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVE 3745
Query: 1880 KLASDLKALSEKEESTK-NQLLIQTEQN--KQLELEIEKLYGSLQMKQMENTLLKDGNEK 1710
L + +L ES K ++ + E+ KQ++ E+E+ ++ ++E + ++
Sbjct: 3746 DLQHKIISLDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLET---QHDRQR 3802
Query: 1709 IYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGI 1530
+ ++ + + ++ E ++D+ + ++ +E +S K + +
Sbjct: 3803 VEEMTAQITKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKT 3862
Query: 1529 LEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRL 1350
L +K+D+ KE L I R D LE+M + + E + + +++ +
Sbjct: 3863 RSELYKVKEDLEKQKENTLAEIQKERED-------LEKMNENITIEMHEIKHQEEQMKQK 3915
Query: 1349 QAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAEL 1170
Q E+D ++ E++ Q L+ E + K+ R + + + N+ ++K E
Sbjct: 3916 QDELDQLK---TEIQNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNER 3972
Query: 1169 HLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESK------DLEGYFLRLFEILLG 1008
L + +++E++ +E E + + +++L +LK K + E L + L
Sbjct: 3973 KLLDKDKEEMEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQ 4032
Query: 1007 QHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEA 828
+ + E + + L ++ LI R + L E + V+ + A
Sbjct: 4033 READEIRKIKEETQNERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMA 4092
Query: 827 MSVLISKSLGNGRAN-QREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETK--- 660
+ L R N ++ ++ E + L +++ +L+ +VQK + +M +T
Sbjct: 4093 DLQREKRILEEMRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIES 4152
Query: 659 -----SREAQQMANKLEEMQQTLS-DMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELT 498
RE Q M +L++ + + M LKK+ L+ ++
Sbjct: 4153 ERAVMIREKQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLMSIER 4212
Query: 497 PSRSFKHREGSFIKEINIGDEDDTPL------IQXXXXXXXXXXXKIDTRTSETQ----E 348
S S K +F E + + T L I+ +++ +T++ Q E
Sbjct: 4213 DSESLKLDREAFGNEKEVLKQMKTDLQIQADEIEKIKLETQHDRQRVEEKTAQIQKDRDE 4272
Query: 347 IDTL-MDDNRK--YWNRVSH-FTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMN 180
I+ L ++ NRK N + ++ +S+Q+ L++ + +
Sbjct: 4273 INNLIVETNRKDMVLNEMDRDIEEKIKSIQSDKDMLEK-------------------ERH 4313
Query: 179 SIEKQLKEL-----NIHVMQLVEHN--TRLKKDVKFGFAWANSMHDLNGQEQKLKVDEE 24
++EK EL N+ + +E ++KK++ + MH++ QE+++K ++
Sbjct: 4314 NLEKTRSELARAKENLETQREIERKDIEKMKKNI------SREMHEIKHQEEQMKQKQD 4366
Score = 79.7 bits (195), Expect = 5e-12
Identities = 114/611 (18%), Positives = 267/611 (43%), Gaps = 43/611 (7%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
K S L + +Q E E +++ N + KIE N ++E+ + E + + +
Sbjct: 10222 KMKSELMTQRQQMEDERSELDQKIKEANTEKD-KIEKNKEIVERLMAEVEEQRNDFKLKK 10280
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNH----LKEALSMAVDDRAFME 1956
E+ + + ++ + + A +TE + + Q+ + + V + LKE + D+ ++
Sbjct: 10281 EELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIK 10340
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQ-----NKQL 1791
+++ QKE + K ++ ++ +++ + K E+E N Q +Q + Q+
Sbjct: 10341 SIIEETSRQKEDLEK-ISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQV 10399
Query: 1790 ELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKL-------LATKSREVQGQQEGILKQD 1632
+ E+ + + + E L++ N KI ++ + K E+Q QE I+K+
Sbjct: 10400 RKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEK 10459
Query: 1631 INIEDELARTKEVGRSATDMKKVNSD----------AGAKVSGILEMLLPMKDDVFSLKE 1482
E A T ++ D+ ++ S+ K++ ++M+ K+D+ +K
Sbjct: 10460 EKAE---AMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKS 10516
Query: 1481 EVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKR 1302
E++ + + + ++Q K ++ EI + + ++ + IQ EL
Sbjct: 10517 EIMTQKQEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDI 10576
Query: 1301 KNQTLQDESQ---RNAKELWNAKARLNNVMSKNINLESQNRSLK-AELHLQAQKAFQIQE 1134
+ Q + DE +N EL N R+ N+ N ++ + +LK E HL+ +K E
Sbjct: 10577 ERQKIADEQDLLIQNKSELQNENERIRNI---NEVIKKERETLKEMEAHLEKEK-----E 10628
Query: 1133 ERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEE 954
E + E ++E + +++KE + L+ Q ++ + E
Sbjct: 10629 EMKSITEETRRQKEDLEKMSTDIKEQN----------QDLMKQR-DLLEQEKEDINHEWT 10677
Query: 953 KLMRILDELICLRNENAKLKNEALYEYHDY--ERKNVSGSRAEAMSVLISKSLGNGRANQ 780
+L + +DE + +K K E L + + ERK++ ++A + + L + + +
Sbjct: 10678 QLQQRIDEFDA---QVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEK 10734
Query: 779 REFQNKEE-------DSSGVDLLKNKCTR----LEFQVQKLSEKAEMFETKSREAQQMAN 633
+ + +EE D +D +K++ R ++ + +KL++ ++ E + + ++M +
Sbjct: 10735 EKEEEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKS 10794
Query: 632 KLEEMQQTLSD 600
++ + +Q + +
Sbjct: 10795 EIMKQRQQMEE 10805
Score = 79.7 bits (195), Expect = 5e-12
Identities = 106/593 (17%), Positives = 267/593 (45%), Gaps = 25/593 (4%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLE-QKDNIIVELSHKLQEN 2127
+E S L + KQ IE + N+ ++ + + +++E + ++ QK+ + +E E
Sbjct: 10805 EERSELENKIKQTYIEKCDIENS-KEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQ 10863
Query: 2126 E---EQRSALQNDMQSVEQMHAVSQTERE---ELNRQLVLLRDDVNHLKEALSMAVDDRA 1965
+ + +S LQN+ + + ++ + + ERE E+ L ++++ + E +D
Sbjct: 10864 DLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRLKED-- 10921
Query: 1964 FMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLEL 1785
+EK D+ Q + + + L +++ K L ++ + Q+ Q EQ+ E
Sbjct: 10922 -LEKMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEK 10980
Query: 1784 EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 1605
+++ SL+ + +K E K +E + ++E +++I + E R
Sbjct: 10981 GMKEDRKSLEETKANVIEMKTKAEPEE------IKKEKEKENEEEEEEEEEIRVIVETER 11034
Query: 1604 TKEVGRSATDMKKVNSDAG---AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
KE+ + +++++V S+ K++ ++M+ K+D+ +K E++ + + +
Sbjct: 11035 -KELYQIKSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSEL 11093
Query: 1433 QVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQ---RNA 1263
++Q K ++ EI + ++ ++ + IQ EL + Q + DE +N
Sbjct: 11094 DNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQNK 11153
Query: 1262 KELWNAKARLNNVMSKNINLESQNRSLK-AELHLQAQKAFQIQEERNVVESEHNVLSSEV 1086
+L N R+ V + ++ + +L+ E+HL+ +K +E R+++E E ++
Sbjct: 11154 AKLQNENERIKKV---DEEIKKERETLREMEIHLKKEK----EELRSIIE-ETQRRKEDL 11205
Query: 1085 ENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNEN 906
E + +++ E K + L ++ + E +L + +DE +
Sbjct: 11206 EKMSTDINEQK-----------LHLKNQRDLLEQEREEINHEMTQLQQRIDEFDA---QV 11251
Query: 905 AKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDL--- 735
+K + + + + ERK++ ++A + + L ++E +++EE V++
Sbjct: 11252 SKQREDLTKQEMEEERKSLEETKARIIEMKTKAEL-QEIMQEKEEEDEEEMRVIVEMERE 11310
Query: 734 --------LKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSD 600
LK + ++ + +KL++ ++ E + + ++M +++ +Q + +
Sbjct: 11311 ELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEE 11363
Score = 77.4 bits (189), Expect = 3e-11
Identities = 122/621 (19%), Positives = 274/621 (44%), Gaps = 65/621 (10%)
Frame = -1
Query: 2273 KQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQ-ENEEQRSALQND 2097
KQ EL++ L ++ E+ E ++E + + I ++ +L+ E E+ + LQN+
Sbjct: 2923 KQEMDELEKTRQNLAKEQENN----ELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNE 2978
Query: 2096 MQSVEQMHAVSQTER-------EELNRQLVLLRD-----DVNHLKEALSMAVDDRAFME- 1956
Q++E+ + +R EEL R+ V+L + ++ + + +R +E
Sbjct: 2979 RQNLEEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIEL 3038
Query: 1955 -KQLQDLENQKETVSKELALSVSREQKLASDLKALSE-----KEESTKNQLLI--QTEQN 1800
K + D+ KE + +L + + ++++A + K+ ++ Q+ I +TEQ
Sbjct: 3039 KKTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQL 3098
Query: 1799 KQLELEIEKLYGSLQMKQMENTLLKDGNEK--IYDLCKLLATKS------REVQGQQEGI 1644
+ E+E+E+L + +Q E + N K I + +L K+ REV E
Sbjct: 3099 RLREVELEQLQALIYRQQDE----IEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYA 3154
Query: 1643 LKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNI 1464
K N+E E +++ + + ++N + G + +ML + ++ + + +
Sbjct: 3155 SKDRANLEKE--KSEMIAQKHQMDIELNKERGL-IEERTQMLNTYEKEMDQKRTALEVEM 3211
Query: 1463 NSLRNDAQMVQVALEQMQDTKSELFAEAE--IRAQEVLR------------LQAEVDAIQ 1326
L+ Q +Q ++Q K EL EA+ + +E R L+ E D +
Sbjct: 3212 KELKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLA 3271
Query: 1325 HILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAF 1146
H+ + KRK+ ++ + ++ K L + S K ++ L+ K
Sbjct: 3272 HLAEDTKRKDDEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQ 3331
Query: 1145 QIQEE-----------RNVVESEHNVLSSEVENLKSEL-KESKDLEGYFLRLFEILLGQH 1002
Q+Q E ++++E+E ++ + ++L +EL K+S+D+E +++ E+L +
Sbjct: 3332 QMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVE---IQMKEVLTEKE 3388
Query: 1001 V-----EVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSR 837
+ ++ D+E+ ++KL+ I + L+ + L+NE E + ++ G
Sbjct: 3389 LLESDRKLLKKDVEN---LQQKLLIIESDSESLKQDRELLENEK--EVLKQMKTDLQGEA 3443
Query: 836 AEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTR----LEFQVQKLSEKAEMF 669
E + + R + Q ++D + + + TR +++Q +++ +K +
Sbjct: 3444 EEIEKIKLETQHERQRVEEMTAQ-IQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDEL 3502
Query: 668 ETKSREAQQMANKLEEMQQTL 606
+ E Q + +LE+ ++ +
Sbjct: 3503 DQLKTEIQNLQQELEKEKEII 3523
Score = 77.0 bits (188), Expect = 3e-11
Identities = 132/656 (20%), Positives = 271/656 (41%), Gaps = 38/656 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQ-HTIELQENFNALRQKNEDIC-LKIEANNNLLEQK--DNIIVELSHKLQ 2133
E S++ +EK+ E+Q + Q E++ LK E N ++ + + EL K Q
Sbjct: 8833 EESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQ 8892
Query: 2132 ENEEQRSALQNDMQSVEQMHAVSQTERE--ELNRQLVLLR---------DDVNHLKEALS 1986
E E R LQ + + +EQ+ E+E E++R+LV DV KE L
Sbjct: 8893 EEESMREILQKEKEELEQLKKDINREKEDIEISRELVESEIYEGEVKGFTDVQKYKEELQ 8952
Query: 1985 MAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALS---EKEESTKNQLLI 1815
+ ++ ++ L+ L + + + + L + K ++L+ ++ +K E +
Sbjct: 8953 IVTEELLTKKRNLEQLNSDVQHLMQTLEEVDIQYIKKKAELEHITSEIQKREQILEKQKK 9012
Query: 1814 QTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKL-----------LATKSRE 1668
+ E+N + EIE + +L+ ME ++ EK + + L + E
Sbjct: 9013 KLEENGWIIEEIEMMKVTLESINMEILQKREDMEKEKENLRREKQETELFRGELQRQRDE 9072
Query: 1667 VQGQQEGI--------LKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLP 1512
V+ ++ + LK D + A ++ + +M+ + AK++ L
Sbjct: 9073 VESSRQALIMEKDQFKLKIDHQRNEMSAAFEKEHKRLENMENDLENQRAKLAESLNDAAK 9132
Query: 1511 MKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDA 1332
M+ + +K E+ + QMV+ +++ K E+ + + +LQ + +
Sbjct: 9133 MEQKLQQMKNELNKEKEQVEEMKQMVKTERVKIEQEKEEMRKQTQEIEDGHEKLQKKTEI 9192
Query: 1331 IQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSL-KAELHLQAQ 1155
+L + ++ L+D S + + + ++ N +E++ RSL + LQ
Sbjct: 9193 ADKLLQDANSESDRLKDLSMK-------LQMQRQDIEKTNTEMETKKRSLDRMSRELQDD 9245
Query: 1154 KAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIE 975
K +++ +R+ E + L + E L ++E++DLE L+ E E+A DIE
Sbjct: 9246 K-IRLKNDRDAYEKDMTHLELKREEL---VRETEDLERKILQQRE-----QDEMAKRDIE 9296
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGN 795
+ A E +M++ +++ RNE AK E +NV R + + + +
Sbjct: 9297 NQTEALE-VMKV--DILKKRNEFAK------------EMENVHSERQKLLLLQGALQSQE 9341
Query: 794 GRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQ 615
R F +++ +C + + AEM ET + E + +EE+Q
Sbjct: 9342 SELENRVFMEEQKHLKQAKAETEECRK---------QLAEMSETVTTEQNEYRKLIEELQ 9392
Query: 614 QTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEIN 447
+ + ++ KK+ ++S ++ +L S +H + + E N
Sbjct: 9393 REKEQL-------EISKNQIEQEKKDLQNMKSNLERQL---ESLRHEKANVEDEKN 9438
Score = 76.3 bits (186), Expect = 6e-11
Identities = 85/437 (19%), Positives = 201/437 (45%), Gaps = 27/437 (6%)
Frame = -1
Query: 2279 EEKQHTIELQENFNALRQKN-EDICLKIEANNNLLEQKDNIIVELSHKL-----QENEEQ 2118
E ++H +E ++ +QK EDI I++ ++LE++ + + +LSH L +E EE
Sbjct: 14093 EAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEEL 14152
Query: 2117 RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEAL------SMAVDDRAFME 1956
L+ + +E + ++E++ + R+ R ++ LKE + ++ D+ ++
Sbjct: 14153 ERLLEKERDDIENCKKIIESEKQSIERE----RAELKRLKEEVEVQHERTLLQQDKNMIQ 14208
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIE 1776
K+ + LE +K ++E+ ++ +S+L L+++ E+ + + E
Sbjct: 14209 KEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQE---------------E 14253
Query: 1775 KLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILK---QDINIE---DE 1614
+L+G + ++E+ L K+ D+ + K ++ Q+ LK +D + DE
Sbjct: 14254 ELHGLPEEIEIEDHLKKED-----DVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDE 14308
Query: 1613 LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
+ +T E + A + + AK ++++ + +V +++ + I L ++
Sbjct: 14309 ITKTDERRQRALEETVATT---AKQPIVIKLEDTLTSEVQEMRDHLNNEIKELARMKTIM 14365
Query: 1433 QVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKEL 1254
++ +Q++ KS++ + E + + E + L++L + L + + KE+
Sbjct: 14366 KMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLDKKNKEI 14425
Query: 1253 WN---------AKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNV 1101
N A+ V+ K +N L+ + Q ++ +IQ + +V +E +
Sbjct: 14426 ENNTETFLKKIAQLETTIVLMKKDKENIENELLQLK---QIEQEREIQRKADVTSTEKEM 14482
Query: 1100 LSSEVENLKSELKESKD 1050
+ +V K+EL++SK+
Sbjct: 14483 YTEKV-TYKTELEDSKE 14498
Score = 75.5 bits (184), Expect = 1e-10
Identities = 129/633 (20%), Positives = 261/633 (41%), Gaps = 64/633 (10%)
Frame = -1
Query: 2303 KEVSRLYEE-EKQHTIELQENFNALRQKNEDICLKIEANNNLLEQK---DNIIVELSHKL 2136
KE+ R +E EK E + L ++ + + LL+ K D + E+ +
Sbjct: 887 KEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLFEMDSER 946
Query: 2135 QENEEQRSALQNDMQSVEQMH-----------AVSQTEREELNR---QLVLLRDDVNHLK 1998
+E E+ R ++N+ + +EQ A Q ++EEL + QLV+ + +N +
Sbjct: 947 KELEQMRFQVENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDTESMNRSR 1006
Query: 1997 EALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLL 1818
E +A DR E + +++ Q+E V+K L + RE+ L L+ E E ++
Sbjct: 1007 E---LARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRL-LRKDMENEREDLEKIR 1062
Query: 1817 IQT-----------EQNKQLELEIEKLYGSLQM-KQMENTLLKDGNEKIYDLCKLLATKS 1674
++T E+ ++ EIE+L+ + Q E + E++ + + +
Sbjct: 1063 VETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRKMEAMKREM 1122
Query: 1673 REVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVF 1494
E++ + + KQ NI+ ++ + ++ N LEM MK D+
Sbjct: 1123 GEIEDMKVELTKQKENIDMKMEHAR--------LEMTN----------LEM---MKADLL 1161
Query: 1493 SLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILI 1314
KE++ + + +++ Q ++V ++ K +L E R +EV++ V+ ++ +
Sbjct: 1162 RQKEDIENQMLAAKSERQQMEVMRTEILKQKEDL----EERLEEVIKENDRVEQMREDVN 1217
Query: 1313 ELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNR--SLKAELHLQAQKAFQI 1140
+ +++ QR + + K + V +K+ ++K+ + + I
Sbjct: 1218 NALKDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAIKSYRASDLELSASI 1277
Query: 1139 QEERNVVESEHNVL---SSEVENLKSELKESK-DLEGYFLRLFEILLGQHVEVASLD--I 978
Q+ER +E ++ E+ +K ++K K D E ++L E + SL
Sbjct: 1278 QKERQELEHYKEIILKEKHELNKIKEDVKAVKNDAEERMIKLHEEEKEMKTKRVSLQNWE 1337
Query: 977 ESCRFAEEKLMRILDELICLRNENAKLKNEA----LYEYHDYERKN---------VSGSR 837
+ +EK + LD + NEN +L + E H K+ +
Sbjct: 1338 RQLQTEKEKNQKGLD---AIWNENQQLNERKQQLDIKELHLQSEKSKLEYKKPLEIKQVD 1394
Query: 836 AEAMSVLISKSLGNGRANQREFQNKEE---DSSGVDLLKNKCT------RLEFQVQKLSE 684
A+ + L+ + A E +K+ + +LL KCT +E +LS
Sbjct: 1395 AQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCTMERQMAEIELSRDELSL 1454
Query: 683 KAEMFETKSREAQQMANKLE----EMQQTLSDM 597
+ +T ++ M +LE E++QT +M
Sbjct: 1455 REATLQTATQTTADMELQLELQKQELEQTKDEM 1487
Score = 75.5 bits (184), Expect = 1e-10
Identities = 134/627 (21%), Positives = 266/627 (42%), Gaps = 97/627 (15%)
Frame = -1
Query: 2189 NNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDV 2010
N LE + E+ ++ + E+ R +L DMQ +EQM + E+EE+ Q + ++
Sbjct: 1760 NRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEK 1819
Query: 2009 NHLKEALSMAVDDR------AFMEKQ-LQD--LENQKETVS-KELALSVSREQKLASDLK 1860
+ L+ L +D EKQ L+D +E QKE +A R+++ ++
Sbjct: 1820 DKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIR 1879
Query: 1859 ALSEKEEST--------KNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIY 1704
EK+E T + + I Q + ++ +I+ + Q E + E+I
Sbjct: 1880 VGIEKQEITFKDLKADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLVEEIE 1939
Query: 1703 DLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKV---SG 1533
K L EV +++ + + +E E ++ +E + K+ N+ A++ S
Sbjct: 1940 KRTKALDEMQMEVDKERQEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESD 1999
Query: 1532 ILEML---LPMKDDVFSLKEEVLG-----------NINSLRNDAQMVQVALEQMQDTKSE 1395
LE+ + + +F L++E LG I+ L+N +M +V +EQMQ K +
Sbjct: 2000 NLELQSENISKERTIFELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQ 2059
Query: 1394 LFAEAEI--------------RAQEVLRLQAEVDAIQ----HI-----LIELKRKNQTLQ 1284
+AE + QE+ L+ E + ++ H+ L E + K+ ++
Sbjct: 2060 QRKKAEYVKTARGRETTALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEME 2119
Query: 1283 DESQRNAKELWNAK-----------ARLNNVMSKNINLESQN-RSLKAELHLQA----QK 1152
+E+ + KE + + + M + +E++N K EL +Q +
Sbjct: 2120 NEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTE 2179
Query: 1151 AFQIQEERNVVE-SEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIE 975
+ ++ ++ VVE S+ + L + + ++L E + + +++ + + Q + +
Sbjct: 2180 TYMLETQKPVVEKSKTDELDEVRKKINADLSEVEKQKSALVQM-NLKISQEESYVKKEKD 2238
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGN 795
+ E + + +L +NE + +A E E +NV R E V I+K
Sbjct: 2239 RLKLQENEQNMQMSQLNAKQNELD--ERQAEMEKQKRELENVM-DRLEKEKVEITKE--K 2293
Query: 794 GRANQREFQNKEEDSSGVDLLKNKCTR-----------LEFQVQKLSEK----AEMFETK 660
R N+ + + K +++S VDL+K + R L +++K+ EK AE FE
Sbjct: 2294 QRVNEMQNEVKRKNAS-VDLIKQEVLREQDHIENSREILNRELEKIKEKKTILAEEFEAL 2352
Query: 659 -------SREAQQMANKLEEMQQTLSD 600
+E Q++ E+Q+ D
Sbjct: 2353 DDKKEMIGKEMQRLGKMKAELQKEAED 2379
Score = 75.5 bits (184), Expect = 1e-10
Identities = 144/718 (20%), Positives = 298/718 (41%), Gaps = 33/718 (4%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQE-N 2127
K + +L +E + +L N + + N D L I+ + LE+ I +L K ++ +
Sbjct: 13714 KTLKQLKDENESKRTQLD---NTIEKMNMDK-LSIQREKDSLEE---IKADLQRKAEKLD 13766
Query: 2126 EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL 1947
EE R A+Q Q +++ +L DD +E SM RA +E+Q
Sbjct: 13767 EEMRKAVQITSQ---------------ISQDAKILDDDREKEEELRSM----RADIERQA 13807
Query: 1946 QDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLY 1767
+ LE+ + + E + + K +DL +++ +N L +Q EL EK
Sbjct: 13808 KILESDVQLLQTE--KEILEKSKTENDLLREDLEKQRKRNDLTLQ-------ELRKEK-- 13856
Query: 1766 GSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGR 1587
+ ++QM + K+ + + L ++ K E++ ++ + +Q + D+L E+ +
Sbjct: 13857 --MALEQMITDITKE-KDAVASLQNEVSLKQHELKNKETELDEQRKEM-DDLRMQLEMRQ 13912
Query: 1586 SATDMKKVNSDA----GAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALE 1419
++T+ ++ D K+ LE + + D+ ++ + +N +
Sbjct: 13913 NSTNKQQQEVDVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAV 13972
Query: 1418 QMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKA 1239
Q D + + + + V + + E+D + +I+ K + Q+L E + +E+ +A
Sbjct: 13973 QQTDELEKFTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRA 14032
Query: 1238 RLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKE 1059
++ ++ +L + +K + + Q A + E++ VE + N+ + +N EL+
Sbjct: 14033 QIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNL--QKQKNELEELRN 14090
Query: 1058 SKDLEGYFLRLFEILLG---QHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNE 888
+ + E + + +I+L + VE I+S R EK L++L + NE + + E
Sbjct: 14091 TIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQE 14150
Query: 887 ALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLE 708
L + ER ++ + S +S+ RA + + + E LL+ ++
Sbjct: 14151 ELERLLEKERDDIENCKKIIESE--KQSIERERAELKRLKEEVEVQHERTLLQQDKNMIQ 14208
Query: 707 FQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVR-------- 552
EK + K+R +++ N EE+++ S++
Sbjct: 14209 ------KEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQEEELHGLPEEI 14262
Query: 551 ----SLKKENTRLRSEM--KGELTPSRSFKHREGS-------FIKEINIGDEDDTPLIQX 411
LKKE+ LR E+ K + S+ F+ + S + EI DE ++
Sbjct: 14263 EIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRALEE 14322
Query: 410 XXXXXXXXXXKI---DTRTSETQEIDTLMDDNRKYWNRVSHFTK-QTQSLQNSVQELQ 249
I DT TSE QE+ +++ K R+ K + L+ + ++Q
Sbjct: 14323 TVATTAKQPIVIKLEDTLTSEVQEMRDHLNNEIKELARMKTIMKMEKDQLKQAKSDIQ 14380
Score = 75.1 bits (183), Expect = 1e-10
Identities = 109/585 (18%), Positives = 249/585 (42%), Gaps = 36/585 (6%)
Frame = -1
Query: 2156 VELSHKLQENEEQ-RSALQNDMQSVE-QMHAVSQ--TEREELNRQLVLLRDDVNHLKEAL 1989
+E KL E +Q R+ + N Q ++ Q +++ TE+ +L R + ++ +++H++E +
Sbjct: 145 IEQIEKLWEGTKQERTEIDNMKQKIQRQQDEITRMTTEKGQLERTITHMKAEIDHIRERM 204
Query: 1988 SMAVD----DRAFMEKQLQDLENQKETVSKELALSVSREQKL-------ASDLKALSEKE 1842
+ +R +E+ DL+ ++ ++ ++ ++ Q L + L
Sbjct: 205 DRNKEEVNRERERVEQMRSDLQAEQSSLQQKRDEIMTERQNLEMIRYETLRQQEELESNR 264
Query: 1841 ESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQ 1662
ESTK+++ + ++++I ++ + Q L++ +I D L K +++
Sbjct: 265 ESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLMEQMKAEIEDEKNELEKKKEDIK 324
Query: 1661 GQQEGILKQDINIEDELARTK-EVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLK 1485
Q++ Q I+ +L + K E+ + + +K + A + E L ++D++ ++
Sbjct: 325 RQRD----QFEQIKLDLQQVKMEMEQRWHETEKEGLEQRAVIQREKEQLKYLQDEIQRVR 380
Query: 1484 EEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELK 1305
EEV N R ++ + Q++ E E + ++LR + +++ ++H E++
Sbjct: 381 EEVERN----REFSKQEHARISQLRAQALEENNLIENKWHDILRKEKDLEEMKH---EIE 433
Query: 1304 RKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERN 1125
R + L + KE + ++ S I++E + +K E ++Q +++
Sbjct: 434 RGREELVMNGELVKKEWEKIEQAKVDIQSHMISMEGRVDEIKRETERLKHIKTEMQRDKD 493
Query: 1124 VVESE---------------HNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVA 990
+E + + +++ E+E+ +E +LE + + + ++
Sbjct: 494 ALEKQKDDTRKAKEEAERKRYEIVTEELEHRARLQRERDELENIRAEMQRVNDVEKAKIL 553
Query: 989 SLDIESCRFAEE-KLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLI 813
ES R EE + R EL+ NA++K E ER N R E M +
Sbjct: 554 KEKEESIRIREEARQERETTELV-----NAEIKAEK-------ERLN---QRQEEM---L 595
Query: 812 SKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMAN 633
+ R + KEE + D+ + ++E ++ + E E K E Q+
Sbjct: 596 RERQEIERIKHETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKE 655
Query: 632 KLE----EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK 510
++E E+++ D+ + L+ E R++ EM+
Sbjct: 656 QMEEAKVELEEEREDLERKRDLVSREIEQAEFLRNEILRVKEEME 700
Score = 75.1 bits (183), Expect = 1e-10
Identities = 143/796 (17%), Positives = 329/796 (41%), Gaps = 40/796 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNL--LEQKDNIIVELSHKLQEN 2127
E+ R+ E ++ T +Q + ++ D+ K N + L Q+ +++ +
Sbjct: 8030 ELERIKTESQRATEHMQSH---AEERAGDLGEKEPVNTRIQRLIQEAEKASKMAWSTKHE 8086
Query: 2126 EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL 1947
E R +Q ++ SVE+ ER++++ + + ++ H +E L D+ K+
Sbjct: 8087 PEMR--MQREV-SVEE----ESVERQDMSANMQRMILEIEHARETLRGMKDEVQAARKER 8139
Query: 1946 QDLENQK-ETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQN----KQLELE 1782
+LEN K E ++ + + + EQ+ + + EK++ +++L+ E+N + +LE
Sbjct: 8140 SELENMKLEFLTMKKNMEKTYEQQ---NDEIQKEKQQIESSKMLLSRERNDLEQNRADLE 8196
Query: 1781 IEKLYGSLQMKQM--ENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELA 1608
+K +L +++ EN LL+ + + + L + E ++ Q + E
Sbjct: 8197 RQKQIMALDKQKLLAENELLEREKADVIKIIENLESLREEATRERATETAQATRRDSEEL 8256
Query: 1607 RTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQV 1428
K S D ++ + + ++ ++ L+ +K D+ + E+ L+ QM +
Sbjct: 8257 MQKMEALSMEDFQEASKNQMVELKRQIDKLIELKADLLQQQTELKKTKADLKQ--QMDDL 8314
Query: 1427 ALEQMQDTKSELFAEAEIRAQEVLRLQAEVD----AIQHILIELKRKNQTLQDESQRNAK 1260
+ + K E +++ R E++ +Q + D IQ + +E KR + L+ E K
Sbjct: 8315 EKTRSEILKHEKDTDSKTRELELIEIQRQKDDLETRIQKLTLE-KRDLEVLRSEIVLEKK 8373
Query: 1259 ELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVEN 1080
+L ++ + + S + E++ + Q+ ++ + +L N
Sbjct: 8374 DLDQKMKQVIRKRDEMEKIRSDIANATEEINRERQELEILRNNVQSARHDFELLLERTAN 8433
Query: 1079 LKSELKESKDLEGYFLRLFEIL---------LGQHVEVASLDIESCRFAEEKLMRILDEL 927
L+ E + D+E L + +I + + +E + ++I+ + ++ R + ++
Sbjct: 8434 LEDEESAATDIERLVLEVVKIREMVRNLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDI 8493
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRA---------EAMSVLISKSLGNGRANQRE 774
+R L E E +++ + RA E+M ++ K + E
Sbjct: 8494 GQIRENLGGLGEE--IEKTRRDKRELEKMRAELAEKQQEQESMREMLHKEREELEQLKDE 8551
Query: 773 FQNKEED----SSGVDLLKNKCTRLEF-QVQKLSEK----AEMFETKSREAQQMANKLEE 621
++ED V+ + +K EF +QK E+ E TK R+ Q+ + +++
Sbjct: 8552 INREKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNSDVQD 8611
Query: 620 MQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIG 441
++QT+ ++ + K+ +L + K EL +E +I E I
Sbjct: 8612 LRQTIEEINIQHGKKRAELEGIGFELKKGEQLLEKQKDEL--------KENGWIVE-EIK 8662
Query: 440 DEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSV 261
++ D+ ++ +D + ++ MD R S +Q + L+ S+
Sbjct: 8663 NKKDS--LEKINMEILRKNEDMDKEKGKLRQEKQEMDLFR------SELQRQREDLETSI 8714
Query: 260 QELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAW 81
Q+L + + I + K+L+ + Q++ ++ K F
Sbjct: 8715 QKLTHEKREME------------VLRSEIVLEKKDLDQKMKQVIRKRDEME---KIRFDI 8759
Query: 80 ANSMHDLNGQEQKLKV 33
AN+ +++G+ Q+L++
Sbjct: 8760 ANARVEIDGERQELEI 8775
Score = 75.1 bits (183), Expect = 1e-10
Identities = 126/646 (19%), Positives = 248/646 (38%), Gaps = 31/646 (4%)
Frame = -1
Query: 2279 EEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQN 2100
EEK +L + + E I K + +EQ EL ++Q E+Q +Q+
Sbjct: 9731 EEKNEMADLSRELQKAKDELEKIAYKTNKERHEVEQMQ---AELHSQIQAIEQQGQIMQD 9787
Query: 2099 DMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKET 1920
+E+ Q + EE+ + + HL L + +E D+E K+
Sbjct: 9788 KQNHLEEKELSIQRKEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQK 9847
Query: 1919 VSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQME 1740
+K+ L +L ++ L E K+ + +Q ++ ++ + +EK+ LQ
Sbjct: 9848 NNKDFELLEKIRSELENEKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQ----- 9902
Query: 1739 NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDIN-IEDELARTKEVGRSATDMKKV 1563
S+ Q ++E K D+N + E+ R K+V D K+
Sbjct: 9903 ---------------------SKREQTEKE---KADLNRVNAEIQREKQV----IDKKRH 9934
Query: 1562 NSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAE 1383
++ +E L +K ++ +E++ L + +VQ+ E + E+ +
Sbjct: 9935 MTNRA------MEELETIKTELKERQEKIQTEQEKLEEEKLLVQIEAENLNKVLEEIKRQ 9988
Query: 1382 AEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRN----------AKELWNAKARL 1233
E L+ + ++ E +RK ++++ Q N K++ K L
Sbjct: 9989 QEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQKQEL 10048
Query: 1232 N--------NVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEH---------- 1107
+++ N+E RSL E L QKA +I +R+ +E E
Sbjct: 10049 QKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNKL 10108
Query: 1106 NVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL 927
+VL +E++N ++E K +++ R K + L+E
Sbjct: 10109 DVLQNEMQNENKAMEEIK----------------------YELDGKRNEINKEQQRLEES 10146
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSS 747
+ NE K + DYE++ + E M V + + + KE D
Sbjct: 10147 LRAINEE---KGDLEIMRADYEKQE---QQIEEMRV------------EAKMERKELDQI 10188
Query: 746 GVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXX 567
+L K+K T ++++ +KL+ M E + + ++M ++L +Q + D
Sbjct: 10189 KSELEKDK-TEIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKE 10247
Query: 566 XIRVRSLKKENTRLRSEMKGELTPSRS-FK-HREGSFIKEINIGDE 435
+ ++N + + E+ R+ FK +E ++ NI DE
Sbjct: 10248 ANTEKDKIEKNKEIVERLMAEVEEQRNDFKLKKEELALERQNIVDE 10293
Score = 75.1 bits (183), Expect = 1e-10
Identities = 118/636 (18%), Positives = 280/636 (44%), Gaps = 27/636 (4%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLE-QKDNIIVELSHKLQEN 2127
KE S L + +Q +E + + ++ E + ++E + ++ QK+ + +E E
Sbjct: 10527 KERSELDNKIQQTDLE-KHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDIERQKIADEQ 10585
Query: 2126 E---EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFME 1956
+ + +S LQN+ + + ++ V + ERE L KE + ++ M+
Sbjct: 10586 DLLIQNKSELQNENERIRNINEVIKKERETL--------------KEMEAHLEKEKEEMK 10631
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIE 1776
++ QKE + K + Q L L +++E ++ ++ + + ++
Sbjct: 10632 SITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQVS 10691
Query: 1775 K-----LYGSLQMKQMENTLLKDGNEKIYDL---CKLLATKSREVQGQQEGILKQDINIE 1620
K L +MK+ E L++ +I ++ +L K + + ++E ++ + ++
Sbjct: 10692 KQKEEDLTKQKEMKE-ERKSLEETKARIIEMKTKAELEDIKKEKEKEEEEEEMRVKVEMD 10750
Query: 1619 DELARTKEVGRSATDMKKVNSDAG---AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRN 1449
KE+ R +++K+ S+ K++ +++ K ++ +K E++ +
Sbjct: 10751 G-----KELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKSEIMKQRQQMEE 10805
Query: 1448 DAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQ- 1272
+ ++ ++Q K ++ EI + ++ ++ + IQ EL + Q + DE
Sbjct: 10806 ERSELENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDL 10865
Query: 1271 --RNAKELWNAKARLNNVMSKNINLESQNRSLK-AELHLQAQKAFQIQEERNVVESEHNV 1101
+N EL N R+ N+ N ++ + +LK E HL+ +K EE V E
Sbjct: 10866 LIQNKSELQNENERIRNL---NEIIKKERETLKEMEAHLEKKK-----EEIKSVSEETRR 10917
Query: 1100 LSSEVENLKSEL-KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL- 927
L ++E + +++ K++KD L+ Q ++ + E ++L + +DE
Sbjct: 10918 LKEDLEKMSTDVNKQNKD-----------LMNQR-DLLEQEREEINHKWKQLQQRIDEFD 10965
Query: 926 --ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEED 753
+ + E K + + E +RK++ ++A + + +K+ ++E +N+EE+
Sbjct: 10966 AQVSKQKEQDLPKEKGMKE----DRKSLEETKANVIE-MKTKAEPEEIKKEKEKENEEEE 11020
Query: 752 SSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXX 573
E +V +E+ E+++ KS E +++ ++++ Q+ L+D
Sbjct: 11021 EE----------EEEIRVIVETERKELYQIKS-ELERVRSEIDHEQKKLNDYMKMIEQEK 11069
Query: 572 XXXIRVRS-LKKENTRL---RSEMKGELTPSRSFKH 477
+++S + K+ ++ RSE+ ++ + KH
Sbjct: 11070 EDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKH 11105
Score = 74.3 bits (181), Expect = 2e-10
Identities = 113/597 (18%), Positives = 256/597 (42%), Gaps = 32/597 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNL------LEQKDNIIVELSHK 2139
E RL + +++ E QE R K+E + K E N+ E+ + + E+ +
Sbjct: 583 EKERLNQRQEEMLRERQE---IERIKHETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQ 639
Query: 2138 LQENEEQRSALQNDMQSVEQMHAVSQTEREELNR----------QLVLLRDDVNHLKEAL 1989
+++ E++ +Q + +E+ + ERE+L R Q LR+++ +KE +
Sbjct: 640 IEDIEKKVEEIQKTKEQMEEAKVELEEEREDLERKRDLVSREIEQAEFLRNEILRVKEEM 699
Query: 1988 SMA--------VDDRAFMEKQLQDLEN-QKETVSKELALSVSREQKLA--SDLKALSEKE 1842
V+ RA + +L+ LE ++ET + + S+ + + L L +
Sbjct: 700 ESRWRETETEEVELRAKTQHELERLEKLREETERSQKNIEESKIELMLWKESLDKLKGEM 759
Query: 1841 ESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQ 1662
E K+ +++Q + K E ++ + L++++ E T+ ++ ++ D + + +
Sbjct: 760 EEDKHVVIMQMNEAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQH 819
Query: 1661 GQQEGILKQDINIEDELARTKEVGRSATDM--KKVNSDAGAKVSGILEMLLPMKDDVFSL 1488
+ E + +N E E A ++ +M KK ++ + ++ L +D++
Sbjct: 820 AEMEDWFRV-VNKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKK 878
Query: 1487 KEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIEL 1308
EE + + + Q + LE+M+ + E + ++ + + V+ ++ L++
Sbjct: 879 AEE----LEQINKEIQRARQELEKMRYFEKESLQKM---LEDTQQERVFVEQVRSELLKN 931
Query: 1307 KRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEER 1128
K E KEL + ++ N + +LE + + + +++ Q+Q ++
Sbjct: 932 KADQDKCLFEMDSERKELEQMRFQVEN---EKKDLEQRRYEM---MRYDVEQSAQVQRQK 985
Query: 1127 NVVESEHNVLSSEVENL-KSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEK 951
+E + L + E++ +S +D E L + EI + E + +E + EE
Sbjct: 986 EELEKIKSQLVIDTESMNRSRELARQDREKAELLIVEIQ--EQREDVNKRLEETKQREEA 1043
Query: 950 LMRILDELICLRNENAKLKNEALYEYHDYE--RKNVSGSRAEAMSVLISKSLGNGRANQR 777
L + ++ R + K++ E L YE ++ ++ RAE + G+ ++
Sbjct: 1044 LRLLRKDMENEREDLEKIRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREK 1103
Query: 776 EFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTL 606
KEE ++ +K + +E +L+++ E + K A+ LE M+ L
Sbjct: 1104 INHEKEEMIRKMEAMKREMGEIEDMKVELTKQKENIDMKMEHARLEMTNLEMMKADL 1160
Score = 71.6 bits (174), Expect = 1e-09
Identities = 115/638 (18%), Positives = 266/638 (41%), Gaps = 70/638 (10%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDI-----------CLKIEANNNL------LE 2175
+E++ L EE K+ + E++ +R++ E I + N N+ ++
Sbjct: 6944 EEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQ 7003
Query: 2174 QKDNIIVELSHKLQEN----EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVN 2007
QK N + ++S ++ + E+++ +Q + +E+MH Q ++E + L + D+
Sbjct: 7004 QKRNALEKMSKEISRDRMKLEDEKKEIQLAREELERMHGDMQRQQEAKDHLLSGITDESL 7063
Query: 2006 HLKEALSMAVD----DRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKA------ 1857
K + + D+A ++ + ++ K+ V + + + L D ++
Sbjct: 7064 LKKSEAEIVLQPSQVDKAKPARKTEISDSDKQPVFVQQMPEMDLKDALKKDFESEKLDLP 7123
Query: 1856 -----LSEKEESTKNQLLIQTEQNK--QLELEIEKLYGSLQMKQMENTLLKDGNEKIYDL 1698
L + ++ Q LI+ E +K Q+ E++K ++ K+ + +++ +K+ D+
Sbjct: 7124 KVKDVLPQDQQMKLEQKLIEDEMDKLKQMRAELQKEADQIEKKKQD---MQNERQKLDDM 7180
Query: 1697 CKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEML 1518
L + R + E I Q +N + + + TD +++ ++ + +
Sbjct: 7181 AARLQEERRTNERLNEEINIQKVNQQKQATAFQ---MEKTDFERIKTEIDQANKELADQQ 7237
Query: 1517 LPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEV 1338
K + +++E N ++ V+ + + S A+++ +++L+ Q E+
Sbjct: 7238 EKNKKTITEMQKERETLEEMRANISKQVETITNENKSLSSRESELAKLQ-EDILQQQQEM 7296
Query: 1337 DAIQH-ILIELKRKNQT----------LQDESQRNAKELWNAKARLNNVMSKNINLESQN 1191
D +++ I++E+ + +Q + D E+ N + V+++ N++S
Sbjct: 7297 DELKNTIMMEMCQLDQRQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQTRNIKSDM 7356
Query: 1190 RSLKAELHLQAQKAFQIQEERNVVESEHNVLSS--------------EVENLKSELK--- 1062
SLK E Q ++ EE++++E E +L+ E+ENLK E +
Sbjct: 7357 VSLKMEKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIK 7416
Query: 1061 -ESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL-ICLRNENAKLKNE 888
E K+LE + L +G E + + EE + +L I R K E
Sbjct: 7417 NEKKELEKMKISLQRKAIG-FKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEE 7475
Query: 887 ALYEYHDYERKN-VSGSRAEAMSVLISKSLGNGRANQRE-FQNKEEDSSGVDLLKNKCTR 714
L + RK + + + K+ ++ E ++ + E + + LK T
Sbjct: 7476 RLDQTEKKRRKTYYTEDLFQEEKTDLQKTKEEINYDREEIYRQRTELNKEKETLKQMHTS 7535
Query: 713 LEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSD 600
+++ + ++ E + E Q+ +L+ Q+ + D
Sbjct: 7536 NLKEIENIEKEKEKIQRTWNELDQIRAELQNKQRDMDD 7573
Score = 70.9 bits (172), Expect = 2e-09
Identities = 128/646 (19%), Positives = 260/646 (40%), Gaps = 99/646 (15%)
Frame = -1
Query: 2258 ELQENFNALRQ-----KNEDICLKIEANNNLLEQKD--NIIVELSHKLQENEEQRSALQN 2100
ELQ +R KNE LK + ++K+ +II E S + ++ E+ + +
Sbjct: 10303 ELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNV 10362
Query: 2099 DMQSVEQMHAVSQTEREELNRQLVLLRDDVNH-------------------------LKE 1995
Q ++ + EREE+N + + ++ L+E
Sbjct: 10363 QKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEE 10422
Query: 1994 ALSMAVDDRAFME-------KQLQDLENQKETVSKE--------LALSVSRE-------- 1884
++ + E +++++L+ +E + KE + L + RE
Sbjct: 10423 VNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSE 10482
Query: 1883 ------------QKLASDLKAL-SEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQM 1743
+KL D+K + EKE+ K + I T Q +++E E +L +Q +
Sbjct: 10483 LVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMT-QKQEMEKERSELDNKIQQTDL 10541
Query: 1742 ENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDE----LARTKEVGRSATD 1575
E ++ E + L + + E+Q Q+E + + I DE + E+
Sbjct: 10542 EKHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDIERQKIADEQDLLIQNKSELQNENER 10601
Query: 1574 MKKVNSDAGAKVSGILEM---LLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDT 1404
++ +N + + EM L K+++ S+ EE L + ++ + +
Sbjct: 10602 IRNINEVIKKERETLKEMEAHLEKEKEEMKSITEETRRQKEDLEKMSTDIKEQNQDLMKQ 10661
Query: 1403 KSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNV 1224
+ L E E E +LQ +D + + K ++ T Q E + K L KAR+ +
Sbjct: 10662 RDLLEQEKEDINHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEM 10721
Query: 1223 MSK----NINLESQNRSLKAELHLQAQK--------AFQIQEERNVVESEHNVLSSE--- 1089
+K +I E + + E+ ++ + +++ ER+ ++ E L+ +
Sbjct: 10722 KTKAELEDIKKEKEKEEEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKI 10781
Query: 1088 -------VENLKSE-LKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILD 933
+E +KSE +K+ + +E L + ++E DIE+ + +KLM ++
Sbjct: 10782 IEQEKQNLEKMKSEIMKQRQQMEEERSELENKIKQTYIE--KCDIENSKEIVQKLMVEVE 10839
Query: 932 ELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEED 753
E + + + E L D ER+ + A+ +LI N+ E QN+ E
Sbjct: 10840 E----QKHEIQFQKEEL----DIERQKI----ADEQDLLIQ--------NKSELQNENER 10879
Query: 752 SSGV-DLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEM 618
+ +++K + L+ L +K E ++ S E +++ LE+M
Sbjct: 10880 IRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRLKEDLEKM 10925
Score = 70.1 bits (170), Expect = 4e-09
Identities = 121/594 (20%), Positives = 247/594 (41%), Gaps = 45/594 (7%)
Frame = -1
Query: 2258 ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQ 2079
+++EN L ++ IE + + + EL+ K QE E R L + + +EQ
Sbjct: 8495 QIRENLGGLGEE-------IEKTRRDKRELEKMRAELAEKQQEQESMREMLHKEREELEQ 8547
Query: 2078 MHAVSQTERE--ELNRQLV----------------LLRDDVNHLKEALSMAVDDRAFMEK 1953
+ E+E E+ R+LV ++++ + E L D +
Sbjct: 8548 LKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNS 8607
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEK 1773
+QDL E ++ + + + + +LK + E K++L ++N + EI+
Sbjct: 8608 DVQDLRQTIEEINIQHGKKRAELEGIGFELKKGEQLLEKQKDEL----KENGWIVEEIKN 8663
Query: 1772 LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSR------EVQGQQEGILKQDINIEDEL 1611
SL+ ME +L+ + + KL K E+Q Q+E L+ I
Sbjct: 8664 KKDSLEKINME--ILRKNEDMDKEKGKLRQEKQEMDLFRSELQRQRED-LETSIQKLTHE 8720
Query: 1610 ARTKEVGRSATDMKKVNSDAGAK-VSGILEMLLPMKDDVFSLKEEVLG---NINSLRNDA 1443
R EV RS ++K + D K V + + ++ D+ + + E+ G + LR++
Sbjct: 8721 KREMEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRFDIANARVEIDGERQELEILRDNV 8780
Query: 1442 QMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNA 1263
Q + E++ + + L E E A ++ RL EV I+ ++ LK + + +ES+
Sbjct: 8781 QSARQDFERLVERTANLEVE-ESAATDIERLVLEVVKIREMVRNLKGEMERRMEESKVEI 8839
Query: 1262 KELWNAKARLNNVMSKNINLESQNRSLKAEL--------HLQAQKAFQIQEERNVVESEH 1107
E K+ + ++ + LK E+ +L+ KA +++E++ ES
Sbjct: 8840 DEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKA-ELEEKQQEEESMR 8898
Query: 1106 NVL---SSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRIL 936
+L E+E LK ++ K+ L E + + D++ + E+L +
Sbjct: 8899 EILQKEKEELEQLKKDINREKEDIEISRELVESEIYEGEVKGFTDVQKYK---EELQIVT 8955
Query: 935 DELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEE 756
+EL+ + +L ++ + E ++ + +A I+ + R E Q K+
Sbjct: 8956 EELLTKKRNLEQLNSDVQHLMQTLEEVDIQYIKKKAELEHITSEI-QKREQILEKQKKKL 9014
Query: 755 DSSG-----VDLLKNKCTRLEFQV-QKLSEKAEMFETKSREAQQMANKLEEMQQ 612
+ +G ++++K + ++ QK + + E RE Q+ E+Q+
Sbjct: 9015 EENGWIIEEIEMMKVTLESINMEILQKREDMEKEKENLRREKQETELFRGELQR 9068
Score = 69.3 bits (168), Expect = 7e-09
Identities = 125/585 (21%), Positives = 244/585 (41%), Gaps = 25/585 (4%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEE 2121
EVS E K EL E R++ +D+ +++E N ++ E+ + EN +
Sbjct: 13879 EVSLKQHELKNKETELDEQ----RKEMDDLRMQLEMRQNSTNKQQQ---EVDVFIVENMK 13931
Query: 2120 QRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQD 1941
R ND++S M + ER +L + D N L + + AV +EK D
Sbjct: 13932 MR----NDLES---MKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTD 13984
Query: 1940 LENQKETVSKEL-ALSVSREQ--KLASDLKALSEKEESTKNQLLIQTEQNKQLE-LEIEK 1773
++ +KE V KE + V ++ K +L++L+ + E K ++ + Q + LE L +
Sbjct: 13985 IKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADL 14044
Query: 1772 LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEV 1593
L G+ +K + T + E K EV+ Q L++ N +EL T E
Sbjct: 14045 LAGADDIKTLVQTEKQMAIED--------TEKKTEVELQMN--LQKQKNELEELRNTIEA 14094
Query: 1592 GRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRND-AQMVQVALEQ 1416
+ + +K+ D K + ++ + DV ++ L ++ + N+ Q Q LE+
Sbjct: 14095 EKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELER 14154
Query: 1415 MQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKAR 1236
+ L+ E D I++ ++ + Q++ +R EL K
Sbjct: 14155 L--------------------LEKERDDIENCKKIIESEKQSI----ERERAELKRLKEE 14190
Query: 1235 LNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVE------SEHNVLSSEVENLK 1074
+ + + + +N K + HL+ +KA +E N+ E SE ++L+ E+E +
Sbjct: 14191 VEVQHERTLLQQDKNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKR 14250
Query: 1073 SE-----LKESKDLEGYFLRLFEILLGQHVEVASLDIE-------SCRFAEEKLMRILDE 930
E L E ++E + + ++L + ++ D + R AE + LDE
Sbjct: 14251 QEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTS--LDE 14308
Query: 929 LICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKE--E 756
+ + + + AL E V+ + + + + + +L + R+ N E E
Sbjct: 14309 I----TKTDERRQRALEE-------TVATTAKQPIVIKLEDTLTSEVQEMRDHLNNEIKE 14357
Query: 755 DSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEE 621
+ ++K + +L+ + + E FE EA + ++ EE
Sbjct: 14358 LARMKTIMKMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNEE 14402
Score = 69.3 bits (168), Expect = 7e-09
Identities = 86/415 (20%), Positives = 173/415 (41%), Gaps = 36/415 (8%)
Frame = -1
Query: 2180 LEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHL 2001
++Q H +++EE+ SA + +V ++ +E +E+ L +DV +
Sbjct: 14986 IQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVARM 15045
Query: 2000 KEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQL 1821
K + M D +E+ D++ Q E + + ++ + + L L+ +E N L
Sbjct: 15046 KTIMKMEKDQ---LEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTL 15102
Query: 1820 LIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKI-YDLCKLLAT-KSREVQ----- 1662
++NK++E E + + L+K E I +L +L T + RE+Q
Sbjct: 15103 ---DKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQEREIQRGTDD 15159
Query: 1661 -GQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDA-GAKVSGILEM---------LL 1515
+ + + + EL KE + D +DA AK G E +L
Sbjct: 15160 TSNEREKYDEKVTYKTELEDNKEKKKPDRDSSLKLTDADSAKTDGEREAQTLETKVQDVL 15219
Query: 1514 PMKDDVFSLKEE----------VLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQ 1365
+ DD +EE ++ +N + D Q ++ ++ KS + E R
Sbjct: 15220 QLTDDTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEKCRSAEEEKSVIMESLERRRN 15279
Query: 1364 EVLRLQAEV----DAIQHILIELKRKNQTLQDESQRNAKEL---WNAKARLNNVMSKNIN 1206
+ ++Q+EV I+H L ++K + Q ++ + QR + + W ++ +
Sbjct: 15280 SLEKVQSEVLTLTQEIEH-LAQIKTEMQQIETKMQRQTRSVATQWETDVQIQQEGQEATE 15338
Query: 1205 LESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-KESKDLE 1044
+ + K+E + A+K ++ V + L+SEV+ ++ L KE +D+E
Sbjct: 15339 TRG-HITKKSEEEISAKKT-----KQPTVTKLEDTLTSEVQEMRDSLNKEMEDVE 15387
Score = 68.9 bits (167), Expect = 9e-09
Identities = 119/605 (19%), Positives = 261/605 (43%), Gaps = 46/605 (7%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQ 2103
E E + +E Q++ + + E+ ++ + + + N +L +LQ +EQ +
Sbjct: 9343 ELENRVFMEEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQREKEQLEISK 9402
Query: 2102 NDMQSVEQMHAVSQTEREELNRQLVLLR-------DDVNHLKEALSMAVDDRAFMEKQLQ 1944
N +EQ Q + L RQL LR D+ N L++ S + + + + K+ +
Sbjct: 9403 NQ---IEQEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKERE 9459
Query: 1943 DLEN-------QKETVSKEL-ALSVSREQ--KLASDLKALSEKEESTKNQLLIQTEQNKQ 1794
DLEN +K+ + +E L + RE+ K+ S+L+ E ES + ++ + E+ Q
Sbjct: 9460 DLENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINNKMEELLQ 9519
Query: 1793 LEL-------EIEKLYGSLQ--MKQMENTL--LKDGNEKIYDLCKL-LATKSREVQGQQE 1650
+++ EIEK LQ +EN ++ +K D+ + + K RE++ Q +
Sbjct: 9520 MKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQLD 9579
Query: 1649 GILKQDINIEDEL-ARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVL 1473
K+ + +E+ + K++ DMK+ + G+LE K ++ K+E+
Sbjct: 9580 ---KETKRLSEEIELKVKDLEMEMADMKRQKQEI-EDTKGLLE---KEKQELKQEKKELE 9632
Query: 1472 GNINSLRNDAQMVQVALEQMQDTKS---ELFAEAEIRAQEVLRLQAEVDAIQHILIELKR 1302
+ L + Q + + K+ +L E EI +++ ++ ++ +Q + + +R
Sbjct: 9633 DQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQR 9692
Query: 1301 KNQTLQDESQRNAKELWNAKARLNN-----VMSKNINLESQNRSLKAELHLQAQK----- 1152
N ++E+++ + L + +S +E +N LQ K
Sbjct: 9693 LNDQTREENKKEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDELEK 9752
Query: 1151 -AFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIE 975
A++ +ER+ VE L S+++ ++ + + +D + + L E+ + + E +
Sbjct: 9753 IAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQDKQNH-LEEKELSIQRKEEEIKIGNT 9811
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGN 795
+ +E L +L+ E K +++ D E ++ + I L N
Sbjct: 9812 EFQIEQEHLNNVLE-------ETNKRQHDLEVMRADIELNKQKNNKDFELLEKIRSELEN 9864
Query: 794 GRANQREFQNKEEDSSGVDL--LKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEE 621
+ + + + +++ V L L+ + RLE +L K E E + + ++ +++
Sbjct: 9865 EKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQTEKEKADLNRVNAEIQR 9924
Query: 620 MQQTL 606
+Q +
Sbjct: 9925 EKQVI 9929
Score = 68.6 bits (166), Expect = 1e-08
Identities = 116/606 (19%), Positives = 255/606 (42%), Gaps = 39/606 (6%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQK-NEDICLK----------IEANNNLLEQKDNII 2157
+ + +L +E ++ ++ E N RQ+ E+I LK I+ L II
Sbjct: 7604 ENIQKLMKELQEERLKTSEALNKERQQFTEEIKLKNDSLDEIQAEIDRQKRALVTDKEII 7663
Query: 2156 VELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAV 1977
+ LQ+ ++ R Q+D + + + Q ERE L++ V + L+ +
Sbjct: 7664 TKQMMDLQKTQDVRR--QSDESDIARANL--QRERESLDQLSVEILKQKQDLERERDELL 7719
Query: 1976 DDRAFMEKQLQDLENQKETVSKELALSVSREQ---KLASDLKALSEKE---ESTKNQLLI 1815
+ +E Q D EN K+ ++ L S E+ +L D + E + +L +
Sbjct: 7720 EQWRLVETQKMDNENVKQLKTELLDEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNL 7779
Query: 1814 QTEQNKQLELEIEKLYGSLQMK------QMENTLLK-----DGNEKIYDLCKLLATKSRE 1668
Q + + ++E++ G LQMK +M+ L + + + Y + L + E
Sbjct: 7780 QKQGIQDERAQLERMKGELQMKADDIERKMQEILYEKQKYAERKSENYKIQTYLDEANAE 7839
Query: 1667 VQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKV---SGILEMLLPMKDDV 1497
VQ + + + D N+E E+ ++ + ++V GAK+ I + L +D +
Sbjct: 7840 VQKLNKELERYDENLE---KCKLELDKARAETERVKQ--GAKIPETQQIEQSLQKERDYI 7894
Query: 1496 FSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHIL 1317
++ + ++ D +++ +++ ++++ + E ++ + + E IQ
Sbjct: 7895 EDIRRNLFKKEEAIEKDKAEIRLRHQELDLIQAKVVKQKEEMVKQKIESERE---IQQEK 7951
Query: 1316 IELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQ 1137
+L+R + L+D+ Q+ +E+ K + K +++++ R + A+K +++
Sbjct: 7952 KKLQRSEEELEDKMQKIKREMIELKLLQDETDGKRKDVDNKMRQV-------ARKRDELE 8004
Query: 1136 EERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAE 957
+ + VES L + L +E E + ++ R E + H E + D+
Sbjct: 8005 KMKADVESASKKLEVDRVMLNTERDELERIKTESQRATE-HMQSHAEERAGDLGEKEPVN 8063
Query: 956 EKLMRILDEL--------ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSL 801
++ R++ E +++ E E ER+++S + + M + I +
Sbjct: 8064 TRIQRLIQEAEKASKMAWSTKHEPEMRMQREVSVEEESVERQDMS-ANMQRMILEIEHAR 8122
Query: 800 GNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEE 621
R + E Q ++ S ++ +K LEF K + +E ++ E Q+ ++E
Sbjct: 8123 ETLRGMKDEVQAARKERSELENMK-----LEFLTMK-KNMEKTYEQQNDEIQKEKQQIES 8176
Query: 620 MQQTLS 603
+ LS
Sbjct: 8177 SKMLLS 8182
Score = 65.5 bits (158), Expect = 1e-07
Identities = 110/608 (18%), Positives = 255/608 (41%), Gaps = 40/608 (6%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIE--LQENFNALRQKNEDICLKIEANNNLLEQKDNI-----IVELSH 2142
E+ +L + E++ I+ + N +E + K E ++ ++K + + +
Sbjct: 14797 ELLQLKQTEQEREIQRGTDDTSNERENYDEKVTYKTELEDSKEKKKPDRDSSLKLTDADS 14856
Query: 2141 KLQENEEQRSALQNDMQSVEQMHAVSQTEREEL-----NRQLVLL-----RDDVNHLKEA 1992
+ E + L+ +Q V Q+ + ++EEL N+ ++L + D+ LKE
Sbjct: 14857 AKTDGEREAQTLETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEE 14916
Query: 1991 LSMAVDDRAFMEKQLQDLENQKETVSKELALSVSRE----QKLASDLKALSEKEESTKNQ 1824
A ++++ + + L+ N E V E+ LS+++E ++ ++++ + K +
Sbjct: 14917 CRSAEEEKSVIMESLERRRNSLEKVQSEV-LSLTQEIDHLAQIKTEMQQIEIKMQIQTRS 14975
Query: 1823 LLIQTEQNKQLEL--EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQE 1650
+ Q E + Q++ E + G + K E K + + KL T + EVQ ++
Sbjct: 14976 VATQWETDVQIQQGQEATETTGHITKKSEEEISAKKTKQPT--VTKLEDTLTSEVQEMRD 15033
Query: 1649 GILKQDINIEDELARTKEVGRSATD-MKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVL 1473
+ K+ +++AR K + + D +++ SD ++ + ++ +E++L
Sbjct: 15034 SLNKE----MEDVARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLL 15089
Query: 1472 G---NINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKR 1302
+ L N +E +T + A+ E ++ ++ + + I++ L++LK+
Sbjct: 15090 QLTHDKEDLSNTLDKKNKEIENNTETSLKKIAQLETT---IVLMKKDKENIENELLQLKQ 15146
Query: 1301 KNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNV 1122
Q + E QR + N + + + ++ LE K + + K +
Sbjct: 15147 TEQ--EREIQRGTDDTSNEREKYDEKVTYKTELEDNKEKKKPDRD-SSLKLTDADSAKTD 15203
Query: 1121 VESEHNVLSSEVENL----KSELKESKDLEGYFLRLFEILLGQHVEVASLDI----ESCR 966
E E L ++V+++ ++ ++L +I+L + A D+ E CR
Sbjct: 15204 GEREAQTLETKVQDVLQLTDDTTQDQEELHDEMENKMKIIL--ELNEAKKDLQKLKEKCR 15261
Query: 965 FAEEKLMRILDELICLRNENAKLKNEAL---YEYHDYERKNVSGSRAEAMSVLISKSLGN 795
AEE+ I++ L RN K+++E L E + + E ++S+
Sbjct: 15262 SAEEEKSVIMESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIETKMQRQTRSVAT 15321
Query: 794 GRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEK--AEMFETKSREAQQMANKLEE 621
+ Q + ++++ K + E +K + ++ +T + E Q+M + L +
Sbjct: 15322 QWETDVQIQQEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNK 15381
Query: 620 MQQTLSDM 597
+ + M
Sbjct: 15382 EMEDVERM 15389
Score = 63.2 bits (152), Expect = 5e-07
Identities = 119/611 (19%), Positives = 253/611 (41%), Gaps = 43/611 (7%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQ---- 2133
E+ +L + E++ E+Q + + E K+ L + K+ I + L+
Sbjct: 14456 ELLQLKQIEQER--EIQRKADVTSTEKEMYTEKVTYKTELEDSKEKIKPDRDSTLELTDT 14513
Query: 2132 -----ENEEQRSALQNDMQSVEQMHAVSQTEREEL-----NRQLVLL-----RDDVNHLK 1998
+ E + L+ +Q V Q+ + ++EEL N+ ++L + D+ LK
Sbjct: 14514 DSAKTDGEREAQTLETKVQDVLQLTDDTTQDQEELHDEMENKMKIILELNKAKKDLQKLK 14573
Query: 1997 EALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSRE----QKLASDLKALSEKEESTK 1830
E A ++++ + + L+ N E V E+ LS+++E ++ ++++ + K +
Sbjct: 14574 EECRSAEEEKSVIMESLERRRNSLEKVQSEV-LSLTQEIDHLAQIKTEMQQIEIKMQIQT 14632
Query: 1829 NQLLIQTEQNKQLELEIEK---LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQG 1659
+ Q E + Q++ E ++ G + K E K + I + KL T + EVQ
Sbjct: 14633 RSVATQWETDVQIQQEGQEPIETTGHITKKSEEEISAKKTKQPI--VTKLEDTLTSEVQE 14690
Query: 1658 QQEGILKQDINIEDELARTKEVGRSATD-MKKVNSDAGAKVSGI---LEMLLPMKDDVFS 1491
+ D+ IED +AR K + + D +++ SD ++ +E L K
Sbjct: 14691 MR------DMEIED-VARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEETLKEKSRNEE 14743
Query: 1490 LKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIE 1311
++L + + L N +E + T A+ E + ++ + + I++ L++
Sbjct: 14744 TLLQLLHDKDDLSNTLDEKSKEIENITVTFKRNIAQLETT---IAMMKKDKENIENELLQ 14800
Query: 1310 LKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEE 1131
LK+ Q + E QR + N + + ++ LE K + + K
Sbjct: 14801 LKQTEQ--EREIQRGTDDTSNERENYDEKVTYKTELEDSKEKKKPDRD-SSLKLTDADSA 14857
Query: 1130 RNVVESEHNVLSSEVENLKS----ELKESKDLEGYFLRLFEILLGQHVEVASLDI----E 975
+ E E L ++V+++ ++ ++L +I+L + A D+ E
Sbjct: 14858 KTDGEREAQTLETKVQDVLQLTDYTTQDQEELHDEMENKMKIIL--ELNEAKKDLQKLKE 14915
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEAL---YEYHDYERKNVSGSRAEAMSVLISKS 804
CR AEE+ I++ L RN K+++E L E + + E + ++S
Sbjct: 14916 ECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRS 14975
Query: 803 LGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEK--AEMFETKSREAQQMANK 630
+ + Q +E + + K + E +K + ++ +T + E Q+M +
Sbjct: 14976 VATQWETDVQIQQGQEATETTGHITKK-SEEEISAKKTKQPTVTKLEDTLTSEVQEMRDS 15034
Query: 629 LEEMQQTLSDM 597
L + + ++ M
Sbjct: 15035 LNKEMEDVARM 15045
Score = 62.4 bits (150), Expect = 8e-07
Identities = 116/583 (19%), Positives = 257/583 (44%), Gaps = 75/583 (12%)
Frame = -1
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDV----NHLKEALSMAVDDRAFME 1956
E +++Q + Q +E + E+ ELN+ +++DV N +E + ++ M+
Sbjct: 1272 ELSASIQKERQELEHYKEIILKEKHELNK----IKEDVKAVKNDAEERMIKLHEEEKEMK 1327
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSE-KEESTKNQLLIQTEQNK---QLE 1788
+ L+N + + E + + ++ + L+E K++ +L +Q+E++K +
Sbjct: 1328 TKRVSLQNWERQLQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSEKSKLEYKKP 1387
Query: 1787 LEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELA 1608
LEI+++ +Q + ME+ D I +L K + + ++ ++ +L Q +E ++A
Sbjct: 1388 LEIKQVDAQVQTELMEDASEYDMALSIEELDK----QRQFLEYFKQELLAQKCTMERQMA 1443
Query: 1607 RTKEVGRSATDMKKVNSDAGAKVSGILEMLLPM--------KDDVFSLKEEV-------L 1473
E+ R +++ + + +E+ L + KD++ K EV
Sbjct: 1444 EI-ELSRDELSLREATLQTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGWVDLQ 1502
Query: 1472 GNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEV-----LRLQAE---VDAIQHIL 1317
I R +MV++ LE+ +D + + + E Q + L E ++A + ++
Sbjct: 1503 TQIAESREKEEMVRIELEKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQRKMM 1562
Query: 1316 IELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLK---AELHLQAQKAF 1146
+ KR + ++ E QR + + +K +N+ + N+E+ LK EL +
Sbjct: 1563 EDEKRALENMKYELQRESGYIERSK---HNMHDERQNMENWAEKLKQEWEELEKKRHDMQ 1619
Query: 1145 QIQEER------------------NVVESEHNVL----------SSEVENLKSELKESKD 1050
Q+Q ER N ++++ +VL E+EN KS++K
Sbjct: 1620 QLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIK---- 1675
Query: 1049 LEGYFLRLFEILLGQHVEVASLDIESCRFAEE-KLMRILDELICLRNENAKLKNEALYEY 873
+ Y L+ + L + + DI++ F E+ +L + DE+ E K + + ++
Sbjct: 1676 IREYDLQQMQTDLNRQ-QKEMQDIQNAVFMEKSELKKSQDEIA----EQLKQVGD-MMQF 1729
Query: 872 HDYERKNVSGSRA----------EAMSVLISKSLGNGRANQREFQNKEE--DSSGVDLLK 729
E+ N+ RA M+ L+++ L + + ++E N++ + + L++
Sbjct: 1730 TQNEKDNLDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMR 1789
Query: 728 NKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSD 600
+ + ++ EK EM + + + + +KLE + QTL++
Sbjct: 1790 DMQDLEQMKINLEREKEEM-QLQRQSIAEEKDKLESVLQTLAE 1831
Score = 62.0 bits (149), Expect = 1e-06
Identities = 117/589 (19%), Positives = 235/589 (39%), Gaps = 54/589 (9%)
Frame = -1
Query: 2108 LQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQ 1929
L++ + + V TER EL + L+ + +++ ++ +EK DLE Q
Sbjct: 12814 LESGKDETDGLTEVHTTERRELEITKLALQSEQQEIEKIRQDIDREKNDLEKYRSDLEKQ 12873
Query: 1928 -------KETVSKELALSVSREQKLASDLKALSEKEESTKNQL--------LIQTEQNK- 1797
K+ + E A + + + K+ E+ ES + QL I E NK
Sbjct: 12874 YEEMEICKQNIENERAELEIDLENIIIETKSKQERLESIEVQLQEKNVQMGTILDELNKR 12933
Query: 1796 QLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCK---LLATKSREVQGQQEGILK---Q 1635
Q EL+ K + +QM +T + +E I L K ++ E+Q Q+E + K Q
Sbjct: 12934 QEELDAIKAKTQREKEQMGHTEELEKDELIAILQKREEIVKRHMEEIQNQREELQKEKDQ 12993
Query: 1634 DINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSL---------KE 1482
N++ EL + G+ +M ++ ++ + + L + + F L E
Sbjct: 12994 FGNMQAELQK----GQLEMEMHQLMLNSERDELNGMRVNLEKQKEEFELMQQNLESRRPE 13049
Query: 1481 EVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQ---HILIE 1311
+L +I + + + L + Q+ + +E R +++ +++ E+ Q L E
Sbjct: 13050 SLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKIKQIEGEIKTKQIEMACLEE 13109
Query: 1310 LKRKNQTLQ--------DESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQ 1155
LK+K Q E Q +EL K ++ + L Q K EL
Sbjct: 13110 LKQKELDEQKNMRECENQELQMRREELAKMKTEIDIERDEIQKLRKQYEKEKCELEQIKP 13169
Query: 1154 KAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIE 975
+ + E+ E +H+ + +++LK E +E +E D++
Sbjct: 13170 DLQKREPEKIDAEVQHDEIHGGIDSLKEEREE-------------------IEKMKADLQ 13210
Query: 974 SCRFAEEKLMRILD-ELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVL-ISKSL 801
+ E + I+ E L + A+++ A+ + KN+ + ++L ++K
Sbjct: 13211 NKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIEAILKVTKKQ 13270
Query: 800 GN--GRANQREFQNKEEDSSGVDLLKNKCTRL--------EFQVQKLSEKAEMFETKSRE 651
N + N+ + K E + +L+ + T L EF + K+ E+ +T R
Sbjct: 13271 KNYLEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKMEEREAERKTIERV 13330
Query: 650 AQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGE 504
+MA + E++++ ++ + E T+ +SE++ E
Sbjct: 13331 MDEMAEEHEKIKKEREELVNMEEEIKKQRRVLEESMNEMTKKKSELQHE 13379
Score = 60.5 bits (145), Expect = 3e-06
Identities = 107/584 (18%), Positives = 246/584 (42%), Gaps = 26/584 (4%)
Frame = -1
Query: 2291 RLYEEEKQHTIELQENFNALRQKNEDI-CLKIE---ANNNLLEQKDN---IIVELSHKLQ 2133
RL EE + Q+ A + + D +K E AN L +Q++ I E+ + +
Sbjct: 7193 RLNEEINIQKVNQQKQATAFQMEKTDFERIKTEIDQANKELADQQEKNKKTITEMQKERE 7252
Query: 2132 ENEEQRSALQNDMQSV-EQMHAVSQTERE--ELNRQLVLLRDDVNHLKEALSMAV----- 1977
EE R+ + ++++ + ++S E E +L ++ + +++ LK + M +
Sbjct: 7253 TLEEMRANISKQVETITNENKSLSSRESELAKLQEDILQQQQEMDELKNTIMMEMCQLDQ 7312
Query: 1976 --DDRAFMEKQLQDLENQKET----VSKELALSVSREQKLASDLKALSEKEESTKNQLLI 1815
D ++K++ DL + +T V +E +++ + + SD+ +L ++E+ + L
Sbjct: 7313 RQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLK 7372
Query: 1814 QTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQ 1635
E+ +E E E L +L + +K E L + ++ +++ + K
Sbjct: 7373 LNEEKDLIEKERELLTKNLDHTDKDKMDMKRELEN-------LKVEKETIKNEKKELEKM 7425
Query: 1634 DINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSL 1455
I+++ + KE D + + + A+ + L++ + F EE L
Sbjct: 7426 KISLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFI--EERLDQTEKK 7483
Query: 1454 RNDAQMVQVALEQ----MQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTL 1287
R + ++ +Q TK E+ + E E+ R + E++ + L ++ N
Sbjct: 7484 RRKTYYTEDLFQEEKTDLQKTKEEINYDRE----EIYRQRTELNKEKETLKQMHTSNLKE 7539
Query: 1286 QDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEH 1107
+ ++ +++ L+ + ++ L+++ R + ++ ++ ++ + +++E
Sbjct: 7540 IENIEKEKEKIQRTWNELDQIRAE---LQNKQRDMDDTTNIMMKEKAELARDLENLQNEK 7596
Query: 1106 NVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL 927
+ L EN++ +KE L+ L+ E L + + E + + L I E+
Sbjct: 7597 DELQKSRENIQKLMKE---LQEERLKTSEALNKERQQFT----EEIKLKNDSLDEIQAEI 7649
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRAN-QREFQNKEEDS 750
R + A + ++ + + + R + S RAN QRE + D
Sbjct: 7650 D--RQKRALVTDKEIITKQMMDLQKTQDVRRQ------SDESDIARANLQRE--RESLDQ 7699
Query: 749 SGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEM 618
V++LK K LE + +L E+ + ET+ + + + E+
Sbjct: 7700 LSVEILKQK-QDLERERDELLEQWRLVETQKMDNENVKQLKTEL 7742
Score = 59.7 bits (143), Expect = 5e-06
Identities = 119/587 (20%), Positives = 244/587 (41%), Gaps = 18/587 (3%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
KE + EE + EL+E Q+N+++ E +LLE++ + +LQ+
Sbjct: 12383 KEYESIIEETNRKRTELEEIEVDQSQQNKNV----ETMKDLLEKERKDTEKEREELQKQA 12438
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQ----LVLLRDDVNHLKEALSMAVDDRAFME 1956
+ + E+M S E ++L Q ++ RDD+ KE + ++ ++
Sbjct: 12439 DDLEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQ 12498
Query: 1955 KQLQDLENQKETVSKELA---LSVSREQK-LASDLKALSEKEESTKNQLLIQTEQNK-QL 1791
K++Q+ +N+ E + EL + + +EQK L L ++E+ + + +++ + K Q
Sbjct: 12499 KEIQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLE---IVRVDYEKHQQ 12555
Query: 1790 ELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDEL 1611
++E ++ ++ +++ + K L+ K E G+LK+++
Sbjct: 12556 QIEEMRVKTKMERDELDQLMAK----------MLMDRKENERSKDMIGLLKKEM------ 12599
Query: 1610 ARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQ 1431
+ K N DA E L K + + K+++ ++ +A V+
Sbjct: 12600 -----------EQTKFNLDAQE------EELKLEKQKIQNEKKDLEMFKAEIKREASEVK 12642
Query: 1430 VALEQM--QDTKS-ELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAK 1260
EQ +DTK+ E E + Q V + E + IQ + E+KR + E + K
Sbjct: 12643 TLKEQQLEKDTKAFEALKEEHLPGQFVQQKGGEFERIQ--IDEVKR----ILSEIHKEKK 12696
Query: 1259 ELWNAKARLNNVMSKNINLESQNRSLKAELHL--QAQKAFQIQEERNVVESEHNVLSSEV 1086
EL K L + + ++S+ S + ++ L A + +++ +V S+ +
Sbjct: 12697 ELERNKQILEHQREALLEIKSKQPSERLDVILVSSATQTSDLEDIPDVSASQGETVEKHT 12756
Query: 1085 ENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMR----ILDELICL 918
+ +K E S E Y + + L Q + E + A+ ++ I D I +
Sbjct: 12757 DIIK-EYTTSIPKEEYEI---DKLKQQGDKKLKSTREDTKMADTEVTTQYKYIPDPSIMM 12812
Query: 917 RNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVD 738
+ E+ K + + L E H ER+ + ++ A Q E Q E+ +D
Sbjct: 12813 KLESGKDETDGLTEVHTTERRELEITKL---------------ALQSEQQEIEKIRQDID 12857
Query: 737 LLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDM 597
KN + ++K E+ E+ + Q + N+ E++ L ++
Sbjct: 12858 REKNDLEKYRSDLEKQYEEMEICK------QNIENERAELEIDLENI 12898
>ref|XP_685984.6| PREDICTED: titin isoform X7 [Danio rerio]
Length = 15997
Score = 126 bits (317), Expect = 4e-26
Identities = 169/712 (23%), Positives = 304/712 (42%), Gaps = 41/712 (5%)
Frame = -1
Query: 2258 ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQ 2079
+LQ +L + E + L EA N E I +L K +E E+ + Q+D Q VE+
Sbjct: 5123 DLQHKMFSLDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVEE 5182
Query: 2078 MHAVSQTER-------EELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLE----- 1935
M A Q ER EE NR+ ++L + +KE + DR +EK+ DLE
Sbjct: 5183 MTAQIQKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSK 5242
Query: 1934 --NQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGS 1761
KE + K+ + ++ QK DL+ ++EK + + Q EQ KQ + E+++L
Sbjct: 5243 LLRAKENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTE 5302
Query: 1760 LQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQ---EGILKQDINIEDELARTK-EV 1593
+Q Q E L+ E I L + E+ QQ I++ N +L + K E
Sbjct: 5303 IQNLQQE---LEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEET 5359
Query: 1592 GRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINS--------LRNDAQM 1437
+M+K D + E L MK L+++VL + S L +A
Sbjct: 5360 EEQKQEMEKEKHDFDQSRKSLDEDLKMMK-----LQKQVLEDEKSKLEQMKIELEREAVE 5414
Query: 1436 VQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQ-TLQD--ESQRN 1266
++ E++Q+ + L E +E L E +L E+K N+ TL D + N
Sbjct: 5415 IRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKSN 5474
Query: 1265 AKEL-WNAKARLNNVMSKNINL---ESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVL 1098
+E+ N + +V +K NL E + R L+AE+H Q + +I++E+ +ESE +
Sbjct: 5475 LEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQR---EIEKEKINIESERAAI 5531
Query: 1097 SSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICL 918
+VE+L+ ++ I L + E LD E+ +E L ++ EL
Sbjct: 5532 IKDVEDLQHKI---------------ICLDRDAESLKLDREAFENEKEVLKQMKTELERE 5576
Query: 917 RNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVD 738
+E K+K E HD + R E M+ I K ++ E N E+++ D
Sbjct: 5577 ADEIEKIKLET---QHDRQ-------RVEEMAAQIQK-------DRDEINNLIEETNRKD 5619
Query: 737 LLKNKCTR-LEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXI 561
++ N+ R +E +++ + +M E + + ++ ++L ++++ L
Sbjct: 5620 MVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQ---------KEN 5670
Query: 560 RVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPL------IQXXXXX 399
+ ++KE L + KH+E ++ + D+ T + ++
Sbjct: 5671 TLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEI 5730
Query: 398 XXXXXXKIDTRTSETQEIDTLMDDNRKYW-NRVSHFTKQTQSLQNSVQELQQ 246
++D R SE + T M+D + N K + ++ QE+++
Sbjct: 5731 IMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEK 5782
Score = 101 bits (251), Expect = 2e-18
Identities = 162/831 (19%), Positives = 370/831 (44%), Gaps = 70/831 (8%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLK--IEANNNLLEQKDNIIVELSHKLQE 2130
+E++ +++ +Q E + +QK +D+ + ++ + LE+ ++E+ K +
Sbjct: 11199 EEINHKWKQLQQRIDEFDAQVS--KQKEQDLPKEKGMKEDRKSLEETKANVIEMKTKAEP 11256
Query: 2129 NE---EQRSALQNDMQSVEQMHAVSQTEREELNR---QLVLLRDDVNHLKEALSMAVDDR 1968
E E+ + + + E++ + +TER+EL + +L +R +++H ++ L+ D
Sbjct: 11257 EEIKKEKEKENEEEEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQKKLN---DYM 11313
Query: 1967 AFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALS------EKEESTKNQLLIQTE 1806
+E++ +DLE K + K+ +L + ++ + EK + +L+++ E
Sbjct: 11314 KMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVEVE 11373
Query: 1805 -QNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDI 1629
Q K ++L+ E+L Q E LL K+ + + + E++ ++E + + +I
Sbjct: 11374 EQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKKVDEEIKKERETLREMEI 11433
Query: 1628 NIEDELARTK----EVGRSATDMKKVNSDAGAKVSGILEMLLPMK---DDVFSLKEEVLG 1470
+++ E + E R D++K+++D I E L +K D + +EE+
Sbjct: 11434 HLKKEKEELRSIIEETQRRKEDLEKMSTD-------INEQKLHLKNQRDLLEQEREEINH 11486
Query: 1469 NINSLRN-----DAQM-----------VQVALEQMQDTKSELF-AEAEIRAQEVLRLQAE 1341
+ L+ DAQ+ ++ + +++TK+ + + + QE+++ + E
Sbjct: 11487 EMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEE 11546
Query: 1340 VDAIQ-HILIELKRKN-QTLQDESQRNAKELWNAKARLNNVMSKNINLESQN-RSLKAEL 1170
D + +++E++R+ ++ E +R E+ + + +LN+ K I E ++ +K+E+
Sbjct: 11547 EDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLND-DKKIIEQEKEDLEKMKSEI 11605
Query: 1169 HLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDL-EGYFLRLFEILLGQHVEV 993
Q Q Q++EER+ E ++ + +++E + +++ SK++ + +++ E ++
Sbjct: 11606 MTQRQ---QMEEERS--ELDNKIKQTDLE--RHDIENSKEIVQKLMVKVEEQRKDIRLQK 11658
Query: 992 ASLDIESCRFAEEKLMRILDELICLRNENAKLK---------NEALYEYHDYERKNVSGS 840
LDIE + A+E+ + ++ L+NEN ++K E L E + RK
Sbjct: 11659 EELDIERQKIADEQGL-VVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEM 11717
Query: 839 RA-------------EAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQV 699
R+ E MS ++K NQR+ +E + + +K T+L+ ++
Sbjct: 11718 RSVIEETQRRKKEDLEKMSTDVNKQ-NQDLMNQRDLLKQEREE-----INHKWTQLQQRI 11771
Query: 698 Q----KLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENT 531
++S++ E TK ++ ++ LEE + + +M + + ++E
Sbjct: 11772 DEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKE-EEEVM 11830
Query: 530 RLRSEM-KGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSET 354
R + EM K EL +S R S I DD +I+ +I + +
Sbjct: 11831 RAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQM 11890
Query: 353 QEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSI 174
+E + +D N++ + ++NS + +Q+ M +
Sbjct: 11891 EEERSELD------NKIKQTDLERHDIENSKEIVQKL-------------------MVEV 11925
Query: 173 EKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEEV 21
E+Q K++ + +L ++ + G N N E+ ++DEE+
Sbjct: 11926 EEQRKDIRLQKEELDIERQKIADEQ--GLVVQNKAKLQNENERIKEMDEEI 11974
Score = 100 bits (250), Expect = 2e-18
Identities = 148/763 (19%), Positives = 321/763 (42%), Gaps = 12/763 (1%)
Frame = -1
Query: 2276 EKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQND 2097
E QH + E A QK+ D KI NNL+E+ + + L+ K ++ E++ ++Q+D
Sbjct: 6459 ETQHDRQRVEEMTAQIQKDRD---KI---NNLIEETNRKDMVLNEKNRDIEKKIKSIQSD 6512
Query: 2096 MQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETV 1917
+E+ + + E+ +L +++D+ KE + A ++K+ +DLE E +
Sbjct: 6513 KDMLEK----EKHDLEKTRSELYKVKEDLEKQKE------NTLAQIQKEREDLEKMNENI 6562
Query: 1916 SKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQME- 1740
++E+ +E+++ L + + +N +Q E K+ E+ I K L +Q E
Sbjct: 6563 TREMHEIKHQEEQMNQKQDELDQLKTEIQN---LQQELEKEKEI-IMKARSQLDRRQSEL 6618
Query: 1739 ---NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMK 1569
T + D E + + K L E++ Q++ + K+ N++ E + K
Sbjct: 6619 DKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQK 6678
Query: 1568 KVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELF 1389
+V + K+ + L DD+ +KEE +N Q+++ E+++ + ++
Sbjct: 6679 QVIEEEKNKLEQMKIELEREADDIRKIKEET-------QNKRQILEKMAEELKKERKDVA 6731
Query: 1388 AEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNI 1209
AE +E L A + + +L+++ L++ + +K+ + + + + +
Sbjct: 6732 HLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLRED 6791
Query: 1208 NLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLR 1029
LE L+AE+H Q + + E++ +E E + +VE+L+S++
Sbjct: 6792 ELE----QLQAEIHKQQS---ETEIEKSNIERERAAIIKDVEDLQSKI------------ 6832
Query: 1028 LFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNV 849
I L + E LD E+ +E+L ++ EL +E K+K E +ER+ V
Sbjct: 6833 ---ISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLET-----QHERQRV 6884
Query: 848 SGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMF 669
A+ M + ++ + + K+E D + L+ ++ + + ++
Sbjct: 6885 EEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVL 6944
Query: 668 ETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRV-RSLKKENTRLRSEMKGELTPS 492
E + + +QM LE +S + ++ +LK+E L E+K
Sbjct: 6945 EEEKNKLEQMKIGLEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIK------ 6998
Query: 491 RSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYW 312
R+ + +I + +E +Q + R + +++I+ + ++ K
Sbjct: 6999 -----RKNQVLDKIKVANESTLADLQKEKRILE------EMRENISKQIEDIENEKEKSK 7047
Query: 311 NRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQL 132
R K +Q E+ + + M ++K+ +++ + + ++
Sbjct: 7048 LREDELKKLQTEVQKQQSEIDMEKTNIESERAAMIREKQNM-MTELKKKSEDVEMQMKEI 7106
Query: 131 VE-----HNTR--LKKDVKFGFAWANSMHDLNGQEQKLKVDEE 24
+ HN R LKKDV+ + + + LK+D+E
Sbjct: 7107 LTEKELLHNDRNLLKKDVE---DLQQKLMSIERDSESLKLDKE 7146
Score = 100 bits (249), Expect = 3e-18
Identities = 155/794 (19%), Positives = 326/794 (41%), Gaps = 68/794 (8%)
Frame = -1
Query: 2282 EEEKQHTIELQENFN-ALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQ---- 2118
EE+KQ + ++N + +++ +ED+ + ++ ++E++ N + ++ +LQ ++
Sbjct: 4234 EEQKQEMEKERDNMDQSIKSLDEDLKM-MKLQKQVIEEEKNKLEQMKFELQREADEIRKI 4292
Query: 2117 RSALQNDMQSVEQM------------HAVSQTEREE--LNRQLVLLRDDVNHLKEALSMA 1980
+ QN+ QS+E+M H T+RE+ L+ V + + L+ +
Sbjct: 4293 KEETQNERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRIL 4352
Query: 1979 VDDRAFMEKQLQDLENQKETVS------KELALSVSREQKLASDLKALSEKEEST----- 1833
+ R + KQ +D+EN+KE K+L V ++Q K E E +
Sbjct: 4353 EEMRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREK 4412
Query: 1832 KNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATK-------- 1677
+N + ++++ +E++++++ ++ + ++ LLK E + KL++ +
Sbjct: 4413 QNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQ--KLMSIERDSESLKL 4470
Query: 1676 SREVQGQQEGILKQ---DINIE-DELARTK---EVGRSATDMKKVNSDAGAKVSGILEML 1518
RE G ++ +LKQ D+ I+ DE+ + K + R + K L +
Sbjct: 4471 DREAFGNEKEVLKQMKTDLQIQADEIEKIKLETQHDRQRVEEKTAQIQKDRDEINNLIVE 4530
Query: 1517 LPMKDDVFS-LKEEVLGNINSLRNDAQMVQVALEQMQDTKSELF-------AEAEIRAQE 1362
KD V + + ++ I S+++D M++ ++ T+SEL + EI ++
Sbjct: 4531 TNRKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLEKTRSELARAKENLETQREIERKD 4590
Query: 1361 VLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSL 1182
+ +++ + H + + + + QDE + E+ N + L + SQ
Sbjct: 4591 IEKMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDLR 4650
Query: 1181 KAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-KESKDLEGYFLRLFEILLGQ 1005
++EL Q I E + + E E K E+ KE D + L E L
Sbjct: 4651 QSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLKMM 4710
Query: 1004 HVEVASLDIESCRFAEEK--LMRILDELICLRNE--NAKLKNEALYEYHDYERKNVSGSR 837
++ ++ E + + K L R DE+ ++ E N + E + E ER+++S
Sbjct: 4711 KLQKQVIEEEKSKLKQMKIELEREADEIRKVKEETQNERQIFEKMTEALKKEREDLSEDA 4770
Query: 836 AEAMSVLISKSLGN---------GRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSE 684
VL + N R+N +E +E S + ++NK ++ + +KL +
Sbjct: 4771 KRKNQVLDEMKVANESTLADILRERSNLQEM--RENISKQTEDVENKKEKIRLREEKLKQ 4828
Query: 683 -KAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKG 507
+AE+ + +S ++ +N E + D+ SLK + +E K
Sbjct: 4829 LQAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENE-KE 4887
Query: 506 ELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDD 327
EL ++ RE I++I + + + ++ T + M++
Sbjct: 4888 ELKQMKTELEREADEIEKIKLETQHERQRVE-----------------EMTADFMETMNN 4930
Query: 326 NRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNI 147
RK N K + +Q QE+++ S++K LK + +
Sbjct: 4931 ERKQLN------KNKEEMQEQKQEMEKERHDMDQ------------SRKSLDKNLKMMKL 4972
Query: 146 HVMQLVEHNTRLKK 105
+ E +L++
Sbjct: 4973 QKQVIEEEKNKLEQ 4986
Score = 98.2 bits (243), Expect = 1e-17
Identities = 169/821 (20%), Positives = 350/821 (42%), Gaps = 72/821 (8%)
Frame = -1
Query: 2282 EEEKQHTI-ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
E++K++T+ ++Q+ L + NE+I ++ + EQ ++ K E ++ ++ +
Sbjct: 6538 EKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQ-------MNQKQDELDQLKTEI 6590
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
QN Q +E+ + R +L+R+ L ++ + + ++R ++K +++E QK
Sbjct: 6591 QNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQK 6650
Query: 1925 ETVSKELALSVSREQKLASDLKALS------EKEESTKNQLLIQTE-------------Q 1803
+ + KE + L DLK + E+E++ Q+ I+ E Q
Sbjct: 6651 QEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQ 6710
Query: 1802 NKQ--LELEIEKL--------YGSLQMKQMENTL--LKDGNEKIYDLCKLLATKSREVQG 1659
NK+ LE E+L + + K+ +N+L +K NE + L KS ++
Sbjct: 6711 NKRQILEKMAEELKKERKDVAHLAEDTKREKNSLDEMKVANES--SMADLQKEKS-NLEE 6767
Query: 1658 QQEGILKQDINIEDE----LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFS 1491
+E I KQ +IE E R E+ + ++ K S+ + S I + DV
Sbjct: 6768 MKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVED 6827
Query: 1490 LKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIE 1311
L+ +++ SL DA+ +++ E ++ K EL Q L+ E D I+ I +E
Sbjct: 6828 LQSKII----SLDRDAESLKLDREAFENEKEEL-------KQMKTELEREADEIEKIKLE 6876
Query: 1310 LKRKNQTLQDESQRNAKELWNAKARL--NNVM---------SKNINLESQNRSLKAELHL 1164
+ + Q +++ + + + N + +L N VM K +++ +SL +L +
Sbjct: 6877 TQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKM 6936
Query: 1163 QAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASL 984
+ ++EE+N +E L E + + S++KE E L L + E +
Sbjct: 6937 MKAQKQVLEEEKNKLEQMKIGLEREADEI-SKIKEETQNERQNLEKMANALKEEREYLAE 6995
Query: 983 DIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKS 804
+I ++ ++LD++ K+ NE+ E++ + E M ISK
Sbjct: 6996 EI-------KRKNQVLDKI--------KVANESTLADLQKEKRIL-----EEMRENISKQ 7035
Query: 803 LGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETK--------SREA 648
+ + +N++E S L +++ +L+ +VQK + +M +T RE
Sbjct: 7036 I-------EDIENEKEKSK---LREDELKKLQTEVQKQQSEIDMEKTNIESERAAMIREK 7085
Query: 647 QQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRS-LKKENTRLRSEMKGELTPSRSFKHRE 471
Q M +L++ + + R+ LKK+ L+ ++ S S K +
Sbjct: 7086 QNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIERDSESLKLDK 7145
Query: 470 GSFIKEINIGDEDDTPL------IQXXXXXXXXXXXKIDTRTS----ETQEIDTLMDDNR 321
+F E + T L I+ +++ +T+ E +EI+TL+++ +
Sbjct: 7146 EAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIK 7205
Query: 320 KYWNRV----SHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDM--NSIEKQLK 159
K + + + K+ +++++ +L++ I N++EK K
Sbjct: 7206 KKRDIIDESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQQKRNALEKMSK 7265
Query: 158 ELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLK 36
E++ M+L + KK+++ MH ++Q+ K
Sbjct: 7266 EISRDRMKLEDE----KKEIQLAREELERMHGDMQRQQEAK 7302
Score = 97.1 bits (240), Expect = 3e-17
Identities = 121/592 (20%), Positives = 267/592 (45%), Gaps = 29/592 (4%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQ----KDNIIVELSHKLQ 2133
E+ ++ EE + L++ AL+++ ED+ + + NN +L++ ++ + ++ +
Sbjct: 5414 EIRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKS 5473
Query: 2132 ENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK 1953
EE R + + VE + +EL + + +++ +RA + K
Sbjct: 5474 NLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIK 5533
Query: 1952 QLQDLENQKETVSKEL-ALSVSR-----EQKLASDLKALSEKEESTKNQLLIQTEQNKQL 1791
++DL+++ + ++ +L + R E+++ +K E+E ++ ++T+ ++Q
Sbjct: 5534 DVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIKLETQHDRQ- 5592
Query: 1790 ELEIEKLYGSLQMKQME-NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDE 1614
+E++ +Q + E N L+++ N K D+ +L K+R+++ + + I +D
Sbjct: 5593 --RVEEMAAQIQKDRDEINNLIEETNRK--DM--VLNEKNRDIEEKIKSIQSD----KDM 5642
Query: 1613 LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
L + K D++K S+ L +K+D+ KE L I R D
Sbjct: 5643 LEKEKH------DLEKTRSE-----------LYKVKEDLEKQKENTLAEIQKERED---- 5681
Query: 1433 QVALEQMQDTKSELFAEAEIRAQEVLRLQAEVD----AIQHILIEL-KRKNQTLQDESQR 1269
LE+M + + E + + +++ + Q E+D IQ++ EL K K ++D SQ
Sbjct: 5682 ---LEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQL 5738
Query: 1268 NAK--ELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLS 1095
+ + EL + +N++M N Q K E+ Q Q ++++ER+ ++ L
Sbjct: 5739 DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQ---EMEKERDNMDQSRKSLD 5795
Query: 1094 SEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLR 915
+ + +K + K+ + E L +I L + + S E + ++L ++ +ELI +
Sbjct: 5796 EDQKKMKLQ-KQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREK 5854
Query: 914 NENAKLKNEALYEYHDYERKNVSGSRAEA---MSVLISKSLGNGRANQREFQNKEEDSSG 744
A L + E + V+ + A I + + + +E+ + E++ S
Sbjct: 5855 ESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENISKLKEYIDNEKEKS- 5913
Query: 743 VDLLKNKCTRLEFQVQKLSEKAEMFETK--------SREAQQMANKLEEMQQ 612
L +++ +L+ +VQK K +M +T RE Q M +L++ +
Sbjct: 5914 -KLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKKSE 5964
Score = 96.7 bits (239), Expect = 4e-17
Identities = 117/620 (18%), Positives = 263/620 (42%), Gaps = 66/620 (10%)
Frame = -1
Query: 2282 EEEKQHTI-ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
E++K++T+ E+Q+ L + NE+I +++ + EQ + K E ++ ++ +
Sbjct: 4125 EKQKENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQ-------MKQKQDELDQLKTEI 4177
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
QN Q +E+ + +R EL+ + L ++ + + ++R ++K +++E QK
Sbjct: 4178 QNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQK 4237
Query: 1925 ETVSKELALSVSREQKLASDLKAL--------SEKEESTKNQLLIQTEQNKQLELEIEKL 1770
+ + KE + L DLK + EK + + + +Q E ++ +++ E
Sbjct: 4238 QEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQ 4297
Query: 1769 YGSLQMKQMENTLLKDGNEKIY------------DLCKL--------LATKSREVQGQQE 1650
+++M L+K+ + ++ D ++ L + R ++ +E
Sbjct: 4298 NERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRILEEMRE 4357
Query: 1649 GILKQDINIEDELARTK-------------EVGRSATDMKKVNSDAGAKV-----SGILE 1524
I KQ +IE+E ++K + +S DM+K N ++ V ++
Sbjct: 4358 NISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQNMMT 4417
Query: 1523 MLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFA-------------- 1386
L +DV +E+L L ND+ +++ + M+D K +L +
Sbjct: 4418 ELKKKSEDVEIQMKEILTEKELLENDSNLLK---KDMEDLKQKLMSIERDSESLKLDREA 4474
Query: 1385 ---EAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSK 1215
E E+ Q LQ + D I+ I +E + Q +++++ + K+ + K
Sbjct: 4475 FGNEKEVLKQMKTDLQIQADEIEKIKLETQHDRQRVEEKTAQIQKDRDEINNLIVETNRK 4534
Query: 1214 NINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELK-ESKDLEGY 1038
++ L +R ++ ++ +++ER+ +E + L+ ENL+++ + E KD+E
Sbjct: 4535 DMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLEKTRSELARAKENLETQREIERKDIE-- 4592
Query: 1037 FLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYER 858
+ + S ++ + EE++ + DEL L+ E L+ E
Sbjct: 4593 ----------KMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQNLQQE---------- 4632
Query: 857 KNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGV-DLLKNKCTRLEFQVQKLSEK 681
E +I K+ Q E ++ + + + + +KN+ +L+ ++ E+
Sbjct: 4633 -------LEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQ 4685
Query: 680 AEMFETKSREAQQMANKLEE 621
+ E + + Q L+E
Sbjct: 4686 KQEMEKEKHDFDQSRKSLDE 4705
Score = 96.7 bits (239), Expect = 4e-17
Identities = 128/572 (22%), Positives = 261/572 (45%), Gaps = 11/572 (1%)
Frame = -1
Query: 2282 EEEKQHTIELQEN-FNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
+E+ HT EL+++ A+ QK E+I + +E+ N EL + + ++ L
Sbjct: 13199 KEQMGHTEELEKDELIAILQKREEIVKRH------MEEIQNQREELQKEKDQFGNMQAEL 13252
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
Q +E + +ER+ELN V L E + ++ R E L+D+ +K
Sbjct: 13253 QKGQLEMEMHQLMLNSERDELNGMRVNLEKQKEEF-ELMQQNLESRR-PESLLEDILKEK 13310
Query: 1925 ETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQ 1746
+ V +E+A +S+EQ E +N I +E K++E +I+++ G ++ KQ
Sbjct: 13311 KRV-EEMAAQLSKEQ-------------EEFRN---IMSETIKRME-KIKQIEGEIKTKQ 13352
Query: 1745 MENTLLKDGNEKIYDLCK-LLATKSREVQGQQEGI--LKQDINIE-DELAR-TKEVGRSA 1581
+E L++ +K D K + +++E+Q ++E + +K +I+IE DE+ + K+ +
Sbjct: 13353 IEMACLEELKQKELDEQKNMRECENQELQMRREELAKMKTEIDIERDEIQKLRKQYEKEK 13412
Query: 1580 TDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTK 1401
+++++ D L+ P K D +E+ G I+SL+ + + ++ +Q+
Sbjct: 13413 CELEQIKPD--------LQKREPEKIDAEVQHDEIHGGIDSLKEEREEIEKMKADLQNKL 13464
Query: 1400 SELFAEAEIRAQEVLRLQAEVDAIQHILIELK--RKNQTLQDESQRNAKELWNAKARLNN 1227
E +I +E L+ + I+ + +E + ++ LQDE + L K + N
Sbjct: 13465 REAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIEAILKVTKKQKNY 13524
Query: 1226 VMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDL 1047
+ N NL + L+ + ++ ++ ++ E H S++E ++E K +
Sbjct: 13525 LEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEFH---MSKMEEREAERKTIE-- 13579
Query: 1046 EGYFLRLFEILLGQHVEVASLDIESCRFAEE--KLMRILDELICLRNENAKLKNEALYEY 873
R+ + + +H ++ E EE K R+L+E + NE K K+E +E
Sbjct: 13580 -----RVMDEMAEEHEKIKKEREELVNMEEEIKKQRRVLEESM---NEMTKKKSELQHER 13631
Query: 872 HD-YERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQ 696
+ Y++K + + +I+ +R Q+KE++ +LK + +
Sbjct: 13632 SELYKQK-------QQLEDMIASESKRDVDTERSRQDKEDE----QILKREREEIADMKD 13680
Query: 695 KLSEKAEMFETKSREAQQMANKLEEMQQTLSD 600
+L ++ E ET + +E+MQ L+D
Sbjct: 13681 QLLKEKEDVETTKERINREKEHIEKMQSQLND 13712
Score = 95.9 bits (237), Expect = 7e-17
Identities = 121/615 (19%), Positives = 259/615 (42%), Gaps = 8/615 (1%)
Frame = -1
Query: 2291 RLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRS 2112
R+ E + Q + + +E+ ++ ED E N+LE K E K +E EE+
Sbjct: 12325 RIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQ 12384
Query: 2111 ALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLEN 1932
++ ++ + + E E++ QL +R +++H ++ L+ DD+ +E++ +DLE
Sbjct: 12385 EMRVKVE-------MERKEIEQIKSQLERVRSEMDHEQKKLN---DDKKMIEQEKEDLEK 12434
Query: 1931 QKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQM 1752
K + K+ +L +K ++ +N E ++L +E+EK +Q
Sbjct: 12435 MKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENS----KEIVEKLMVEVEKQKHEIQF 12490
Query: 1751 KQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDM 1572
++ E L +KI D LL E Q + E I + D I+ E KE+ +
Sbjct: 12491 QKEE---LDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNLQKE 12547
Query: 1571 KKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSEL 1392
K+ + E L M D+ K++++ + L+ + + + L Q+Q E
Sbjct: 12548 KEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEF 12607
Query: 1391 FAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKN 1212
+ I + + E+D L + ++ +++ +E+ R EL +
Sbjct: 12608 ETTSNILVTTKMEEKTEMD---EKLQQAIKEYESIIEETNRKRTELEEIE---------- 12654
Query: 1211 INLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFL 1032
++ QN++++ L +++ER E E L + ++L+ ++ E D E
Sbjct: 12655 VDQSQQNKNVETMKDL-------LEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSK 12707
Query: 1031 RLFEI---LLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYE 861
R + LL Q + +E +M+ +EL L+ E KNE + E
Sbjct: 12708 RSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKEIQNQKNEMEEIKCELE 12767
Query: 860 RKNVSGSRAEAMSVLISKSLGNGRANQREFQ----NKEEDSSGVDLLKNKCTRLEFQVQK 693
K + + + + +SL ++ + + E+ ++ ++ K ++ +
Sbjct: 12768 TKRIEIIKEQKR---LEESLNTVNEERQYLEIVRVDYEKHQQQIEEMRVKTKMERDELDQ 12824
Query: 692 LSEKAEMFETKSREAQQMANKLE-EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSE 516
L K M ++ ++ M L+ EM+QT ++ ++++ KK+ ++E
Sbjct: 12825 LMAKMLMDRKENERSKDMIGLLKKEMEQTKFNLDAQEEELKLEKQKIQNEKKDLEMFKAE 12884
Query: 515 MKGELTPSRSFKHRE 471
+K E + ++ K ++
Sbjct: 12885 IKREASEVKTLKEQQ 12899
Score = 94.7 bits (234), Expect = 2e-16
Identities = 148/745 (19%), Positives = 307/745 (41%), Gaps = 60/745 (8%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQ------ENFNALRQKNED-----ICLKIEANNN-----LLEQK 2169
E+ R EE ++ + LQ EN A Q+ ED I +KI+ L ++
Sbjct: 9774 EMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQLDKET 9833
Query: 2168 DNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEAL 1989
+ E+ K+++ E + + ++ Q +E + + E++EL ++ L D + L
Sbjct: 9834 KRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREK 9893
Query: 1988 SMAVDDR---AFMEKQLQDLENQKETVSKELALSVS----------REQKLASDLKALSE 1848
++R ++ QL+DL + E V ++L L S ++Q+L + ++
Sbjct: 9894 QETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENK 9953
Query: 1847 KEESTKNQLLIQTEQNKQ-LELEIEKLYGSL-QMKQMENTL--LKDGNEKI--------Y 1704
KE+ + Q +TEQ KQ LE+ K+ +M + L KD EKI +
Sbjct: 9954 KEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDELEKIAYKTNKERH 10013
Query: 1703 DLCKLLATKSREVQG-QQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAK---VS 1536
++ ++ A ++Q +Q+G + QD E + + R ++K N++ + ++
Sbjct: 10014 EVEQMQAELHSQIQAIEQQGQIMQDKQNHLE-EKELSIQRKEEEIKIGNTEFQIEQEHLN 10072
Query: 1535 GILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSEL--FAEAEIRAQE 1362
+LE + D+ ++ ++ N D ++++ ++++ K +L + E + E
Sbjct: 10073 NVLEETNKRQHDLEVMRADIELNKQKNNKDFELLEKIRSELENEKYDLQIWTEQQKHLVE 10132
Query: 1361 V--LRLQAEVDAIQHILIELKRKNQTLQDES---QRNAKELWNAKARLNNVMSKNINLES 1197
V L+ E + ++ + IEL+ K + + E R E+ K ++
Sbjct: 10133 VQLQELEKEKERLEKMEIELQSKREQTEKEKADLNRVNAEIQREKQVIDKKRHMTNRAME 10192
Query: 1196 QNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEI 1017
+ ++K EL + +K IQ E+ +E E ++ E ENL L+E K +
Sbjct: 10193 ELETIKTELKERQEK---IQTEQEKLEEEKLLVQIEAENLNKVLEEIKRQQ--------- 10240
Query: 1016 LLGQHVEVASLDI----ESCRFAEEKLMR---ILDELICLRNENAKLKNEALYEYHDYER 858
+ +E++ D+ E C A E+ R ++E I NENAK + ER
Sbjct: 10241 ---EKLEISEADLKVMKEQCENAREETERKKCDIEEQI-QNNENAK-------HLLEQER 10289
Query: 857 KNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKA 678
K++ + E + + +K LL+ K + Q L ++
Sbjct: 10290 KDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEKEK 10349
Query: 677 EMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELT 498
E K + + N+++ + + ++ + + +E+ R +E KG+L
Sbjct: 10350 EDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGDLE 10409
Query: 497 PSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRK 318
R+ ++ I+E+ + + + + +ID + +++ R
Sbjct: 10410 IMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKERN 10469
Query: 317 YWNRV-SHFTKQTQSLQNSVQELQQ 246
++ S Q Q +++ EL Q
Sbjct: 10470 DLEKMKSELMTQRQQMEDERSELDQ 10494
Score = 94.4 bits (233), Expect = 2e-16
Identities = 129/603 (21%), Positives = 273/603 (45%), Gaps = 37/603 (6%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEE 2121
E+ R +E ++ +E Q + + + I + + NNL+E+ + + L+ K ++ EE
Sbjct: 4032 ELERETDEIEKIKLETQHDRQRVEEMTAQITKERDKINNLIEETNRKDMVLNEKNRDIEE 4091
Query: 2120 QRSALQNDMQSVE-QMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQ 1944
+ ++Q+D +E + H + +T E L +++D+ KE + A ++K+ +
Sbjct: 4092 KIKSIQSDKDMLEKEKHNLEKTRSE-----LYKVKEDLEKQKE------NTLAEIQKERE 4140
Query: 1943 DLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYG 1764
DLE E ++ E+ +E+++ L + + +N +Q E K+ E+ I K
Sbjct: 4141 DLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEIQN---LQQELEKEKEI-IMKDRS 4196
Query: 1763 SLQMKQME----NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKE 1596
L ++Q E T + D E + + KLL E++ Q++ + K+ N++ + E
Sbjct: 4197 ELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQKQEMEKERDNMDQSIKSLDE 4256
Query: 1595 VGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQ 1416
+ K+V + K+ + L D++ +KEE +N+ Q ++ +
Sbjct: 4257 DLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEET-------QNERQSLEKMTKA 4309
Query: 1415 MQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKAR 1236
+ + +L AE +E L A + + +L+R+ + L++ + +K+ +
Sbjct: 4310 LIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRILEEMRENISKQTED---- 4365
Query: 1235 LNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-KE 1059
+ N K+ E + + L+ E+ Q +I E+ +ESE V+ E +N+ +EL K+
Sbjct: 4366 IENEKEKSKLREDELKKLQTEVQKQQS---EIDMEKTNIESERAVMIREKQNMMTELKKK 4422
Query: 1058 SKDLEGYFLRLFEILLGQHV--------------------------EVASLDIESCRFAE 957
S+D+E +++ EIL + + E LD E+ +
Sbjct: 4423 SEDVE---IQMKEILTEKELLENDSNLLKKDMEDLKQKLMSIERDSESLKLDREAFGNEK 4479
Query: 956 EKLMRILDELICLRNENAKLKNEALYEYHDYERK--NVSGSRAEAMSVLISKSLGNGRAN 783
E L ++ +L +E K+K E ++ E K + R E ++++ + + N
Sbjct: 4480 EVLKQMKTDLQIQADEIEKIKLETQHDRQRVEEKTAQIQKDRDEINNLIVETNRKDMVLN 4539
Query: 782 Q--REFQNK-EEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQ 612
+ R+ + K + S D+L+ + LE +L+ E ET+ RE ++ +E+M++
Sbjct: 4540 EMDRDIEEKIKSIQSDKDMLEKERHNLEKTRSELARAKENLETQ-REIER--KDIEKMKK 4596
Query: 611 TLS 603
+S
Sbjct: 4597 NIS 4599
Score = 94.0 bits (232), Expect = 3e-16
Identities = 135/605 (22%), Positives = 286/605 (47%), Gaps = 41/605 (6%)
Frame = -1
Query: 2291 RLYEEEKQHTIELQENF-NALRQKNEDICLKIEANNNLLEQKDNIIVE---LSHKLQENE 2124
R+ E + Q + +E+ N + + E CL+ E N ++E K +E ++ K++E +
Sbjct: 10642 RIDEFDAQVRKQKEEDLTNQKKMEEERKCLE-EVNGKIIEMKTKAELEHHEINQKIEELQ 10700
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNR---QLVLLRDDVNH----LKEALSMAVDDRA 1965
+ + + + E M + ERE+L++ +LV + +V+H L + + M ++
Sbjct: 10701 TLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKE 10760
Query: 1964 FMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLEL 1785
+EK ++ QK+ + KE + ++ Q+ + + + +E + + EQ +++L
Sbjct: 10761 DLEKMKSEIMTQKQEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRHEIQL 10820
Query: 1784 EIEKLYGSLQMKQMENTL-------LKDGNEKIYDLCKLLATKSREVQGQQEGILKQD-- 1632
+ E+L Q E L L++ NE+I ++ +++ K RE + E L+++
Sbjct: 10821 QKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEVI-KKERETLKEMEAHLEKEKE 10879
Query: 1631 --INIEDELARTKE-VGRSATDMKKVNSDAGAKVSGILEM----------LLPMKDDVFS 1491
+I +E R KE + + +TD+K+ N D K +LE L + D F
Sbjct: 10880 EMKSITEETRRQKEDLEKMSTDIKEQNQDL-MKQRDLLEQEKEDINHEWTQLQQRIDEFD 10938
Query: 1490 L-----KEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQ 1326
KEE L ++ + + +LE+ + E+ +AE+ + + + E +
Sbjct: 10939 AQVSKQKEEDLTKQKEMKEERK----SLEETKARIIEMKTKAELEDIKKEKEKEEEEEEM 10994
Query: 1325 HILIELKRKN-QTLQDESQRNAKELWNAKARLNNVMSKNINLESQN-RSLKAELHLQAQK 1152
+ +E+ K ++ E +R E+ + + +LN+ K I E QN +K+E+ Q Q
Sbjct: 10995 RVKVEMDGKELDRIKSELKRERSEIDHEQKKLND-DKKIIEQEKQNLEKMKSEIMKQRQ- 11052
Query: 1151 AFQIQEERNVVESEHNVLSSEVENLKSELKESKDL-EGYFLRLFEILLGQHVEVASLDIE 975
Q++EER+ E E+ + + +E K +++ SK++ + + + E + LDIE
Sbjct: 11053 --QMEEERS--ELENKIKQTYIE--KCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIE 11106
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGN 795
+ A+E+ + I ++ L+NEN +++N L E ER+ + + M + K
Sbjct: 11107 RQKIADEQDLLIQNKSE-LQNENERIRN--LNEIIKKERETL-----KEMEAHLEKKKEE 11158
Query: 794 GRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQ 615
++ E + +ED L+ T + Q + L + ++ E +E +++ +K +++Q
Sbjct: 11159 IKSVSEETRRLKED------LEKMSTDVNKQNKDLMNQRDLLE---QEREEINHKWKQLQ 11209
Query: 614 QTLSD 600
Q + +
Sbjct: 11210 QRIDE 11214
Score = 92.4 bits (228), Expect = 8e-16
Identities = 119/631 (18%), Positives = 280/631 (44%), Gaps = 68/631 (10%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE- 2124
E + + +Q E+++ N L +K EDI + + + + +E+ + E E
Sbjct: 294 ETQKAKDLMEQMKAEIEDEKNELEKKKEDIKRQRDQFEQIKLDLQQVKMEMEQRWHETEK 353
Query: 2123 ---EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFM-- 1959
EQR+ +Q + + ++ + Q REE+ R + + + + + A+++ +
Sbjct: 354 EGLEQRAVIQREKEQLKYLQDEIQRVREEVERNREFSKQEHARISQLRAQALEENNLIEN 413
Query: 1958 --------EKQLQDLENQKETVSKELALS---VSRE----QKLASDLKALSEKEESTKNQ 1824
EK L++++++ E +EL ++ V +E ++ D+++ E ++
Sbjct: 414 KWHDILRKEKDLEEMKHEIERGREELVMNGELVKKEWEKIEQAKVDIQSHMISMEGRVDE 473
Query: 1823 LLIQTEQNKQLELEIEKLYGSLQMKQMENT--LLKDGNEKIYDLCKLLATKSREVQGQQE 1650
+ +TE+ K ++ E+++ +L+ KQ ++T ++ K Y+ + T+ E + + +
Sbjct: 474 IKRETERLKHIKTEMQRDKDALE-KQKDDTRKAKEEAERKRYE----IVTEELEHRARLQ 528
Query: 1649 GILKQDINIEDELARTKEVGRSATDMKK-------------------VNSDAGA---KVS 1536
+ NI E+ R +V ++ +K VN++ A +++
Sbjct: 529 RERDELENIRAEMQRVNDVEKAKILKEKEESIRIREEARQERETTELVNAEIKAEKERLN 588
Query: 1535 GILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVL 1356
E +L + ++ +K E L + N + E+M+ K+E+ + E ++V
Sbjct: 589 QRQEEMLRERQEIERIKHETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVE 648
Query: 1355 RLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNR---- 1188
+Q + ++ +EL+ + + L+ + ++E+ A+ N ++ +ES+ R
Sbjct: 649 EIQKTKEQMEEAKVELEEEREDLERKRDLVSREIEQAEFLRNEILRVKEEMESRWRETET 708
Query: 1187 ---SLKAELHLQAQKAFQIQEE-----RNVVESEHNVL--SSEVENLKSELKESKD---L 1047
L+A+ + ++ +++EE +N+ ES+ ++ ++ LK E++E K +
Sbjct: 709 EEVELRAKTQHELERLEKLREETERSQKNIEESKIELMLWKESLDKLKGEMEEDKHVVIM 768
Query: 1046 EGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNE----NAKLKNEALY 879
+ + E L +E ++ + EK+ LDE+ +RNE +A++++
Sbjct: 769 QMNEAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQHAEMEDWFRV 828
Query: 878 EYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQV 699
+ E N++ +L+ K + + +R ++ E D ++ K LE Q+
Sbjct: 829 VNKEKEEANLAKLAVHEAEMLLKKQM--EESEKRRYEMITEALEQRDEIQKKAEELE-QI 885
Query: 698 QKLSEKAEMFETKSR--EAQQMANKLEEMQQ 612
K ++A K R E + + LE+ QQ
Sbjct: 886 NKEIQRARQELEKMRYFEKESLQKMLEDTQQ 916
Score = 92.0 bits (227), Expect = 1e-15
Identities = 142/718 (19%), Positives = 312/718 (43%), Gaps = 33/718 (4%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEAN----NNLLEQKDNIIVELSHKLQ 2133
E+ R +E ++ +E Q + RQ+ E++ +I+ + NNL+E+ + + L+ K +
Sbjct: 5572 ELEREADEIEKIKLETQHD----RQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNR 5627
Query: 2132 ENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK 1953
+ EE+ ++Q+D +E+ + + E+ +L +++D+ KE + A ++K
Sbjct: 5628 DIEEKIKSIQSDKDMLEK----EKHDLEKTRSELYKVKEDLEKQKE------NTLAEIQK 5677
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEK 1773
+ +DLE E +++E+ +E+++ L + + +N +Q E K+ E+ I K
Sbjct: 5678 EREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQN---LQQELEKEKEI-IMK 5733
Query: 1772 LYGSLQMKQME----NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 1605
L ++Q E T + D E + + K L E++ Q++ + K+ N++
Sbjct: 5734 DRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKS 5793
Query: 1604 TKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVA 1425
E + K++ + K+ + L D++ +KEE +N Q ++
Sbjct: 5794 LDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEET-------QNKRQRLEKM 5846
Query: 1424 LEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNA 1245
E++ K L AE E L A + + +L+R+ L +E + N +L
Sbjct: 5847 TEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSIL-EEMRENISKL--- 5902
Query: 1244 KARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL 1065
K ++N K+ E + + L+ E+ Q K I E+ +ESE + E +N+ +EL
Sbjct: 5903 KEYIDNEKEKSKLREDELKKLQTEVQKQQSK---IDMEKTNIESERAAMIREKQNMMTEL 5959
Query: 1064 -KESKDLEGYFLRLFEILLGQHV-----EVASLDIESCR----FAEEKLMRILDELICLR 915
K+S+D+E +++ EIL + + ++ + D+E+ + E R+ +
Sbjct: 5960 KKKSEDVE---IQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFE 6016
Query: 914 NEN---AKLKNEALYEYHDYERKNV----SGSRAEAMSVLISKSLGNGRANQREFQNKEE 756
NE ++K + + + E+ + R E M+ I K + + N E
Sbjct: 6017 NEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQK-------ERDKINNLIE 6069
Query: 755 DSSGVDLLKNKCTR-LEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXX 579
+++ D++ N+ R +E +++ + +M E + ++ ++L ++++ L
Sbjct: 6070 ETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQ------ 6123
Query: 578 XXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPL------I 417
+ ++KE + + KH+E ++ + D+ T + +
Sbjct: 6124 ---KENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQEL 6180
Query: 416 QXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYW-NRVSHFTKQTQSLQNSVQELQQ 246
+ + D R SE + T M+D + N K + ++ QE+++
Sbjct: 6181 EKEKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEK 6238
Score = 91.7 bits (226), Expect = 1e-15
Identities = 146/693 (21%), Positives = 299/693 (43%), Gaps = 77/693 (11%)
Frame = -1
Query: 2282 EEEKQHTI-ELQENFNALRQKNEDICLKI-------EANNNLLEQKDNIIVELSHKLQEN 2127
E++K++T+ E+Q+ L + NE+I ++ E N ++ D + E+ + QE
Sbjct: 5665 EKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQEL 5724
Query: 2126 EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL 1947
E+++ + D ++ + EL++Q + D + +K D+ ME+Q
Sbjct: 5725 EKEKEIIMKDRSQLD-------LRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQK 5777
Query: 1946 QDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLY 1767
Q++E +++ + + S+ +QK K + E+E++ Q+ I+ E+ EI K+
Sbjct: 5778 QEMEKERDNMDQS-RKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREAD---EISKIK 5833
Query: 1766 GSLQ-----MKQMENTLLKD------------GNEKIYDLCKL-----LATKSRE---VQ 1662
Q +++M L+++ +KI D K+ +A RE ++
Sbjct: 5834 EETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILE 5893
Query: 1661 GQQEGI--LKQDINIEDELARTKE-----------VGRSATDMKKVN--SDAGAKVSGIL 1527
+E I LK+ I+ E E ++ +E +S DM+K N S+ A +
Sbjct: 5894 EMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQ 5953
Query: 1526 EMLLPMK---DDVFSLKEEVLGNINSLRNDAQMVQVALEQMQ--------DTK-----SE 1395
M+ +K +DV +E+L L ND +++ +E +Q D+K E
Sbjct: 5954 NMMTELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDRE 6013
Query: 1394 LFA-EAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMS 1218
F E E Q LQ + D I+ I +E + Q +++ + + KE +
Sbjct: 6014 AFENEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNR 6073
Query: 1217 KNINLESQNRSLKAELHLQAQKAFQIQEERNVVESE-HNV--LSSEVENLKSELKESKDL 1047
K++ L +NR ++ +K IQ +++++E E HN+ SE+ +K +L++ K+
Sbjct: 6074 KDMVLNEKNRDIE-------EKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKEN 6126
Query: 1046 EGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYE--- 876
++ + + E + ++ + EE++ + DEL L+ E L+ E E
Sbjct: 6127 TLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEI 6186
Query: 875 -YHDYERKNVSGSRAEAMSVLISKSLGNGRANQREF-QNKEEDSSGVDLLKNKCTRLEFQ 702
D + ++ S + ++ + + +++ ++KEE ++ + +
Sbjct: 6187 IMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQS 6246
Query: 701 VQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLR 522
+ L + +M + + + ++ NKLE+M+ L +R +K+E R
Sbjct: 6247 RKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELE----------READEIRKIKEETQNER 6296
Query: 521 ---SEMKGELTPSR-SFKHREGSFIKEINIGDE 435
+M EL + SF H KE I D+
Sbjct: 6297 QSLEKMTEELKKEKESFTHLAEDTKKEQEILDK 6329
Score = 91.3 bits (225), Expect = 2e-15
Identities = 159/754 (21%), Positives = 300/754 (39%), Gaps = 22/754 (2%)
Frame = -1
Query: 2297 VSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQ 2118
++R E+ K+ L E F AL K E I +++ + EL + ++ E+Q
Sbjct: 2582 LNRELEKIKEKKTILAEEFEALDDKKEMI-------GKEMQRLGKMKAELQKEAEDTEKQ 2634
Query: 2117 RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDL 1938
R + ND ++ E+M Q E++++ +RD+ +L+ DR +EK+ DL
Sbjct: 2635 RRDIDNDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLESDRDTLEKERFDL 2694
Query: 1937 ENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQ-TEQNKQLELEIEKLYGS 1761
E K +++K L ++ ES Q IQ E K+ E+ +E+L +
Sbjct: 2695 EKTK------------------TEMKDLEKQLESQSRQHEIQLVEIQKEREI-LEQLKIN 2735
Query: 1760 LQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIE---DELART---- 1602
L ++ + +D EK + + + E Q ++EGI K + I+ DEL +T
Sbjct: 2736 LSKQKEDLEKERDCFEK--EKADISLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNV 2793
Query: 1601 -KEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVA 1425
KE+ + K++ D K+ I L D ++++ N RN+ +MV
Sbjct: 2794 VKELENNEL-QKQIIEDERDKIEQIKAELQKEAKDTEKQRQDI---ENDRRNNEEMV--- 2846
Query: 1424 LEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNA 1245
++Q+ K + ++ D I+ L+ Q L+ + KE ++
Sbjct: 2847 -IKLQNEKKD--------------IETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDL 2891
Query: 1244 KARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL 1065
K + LESQNR + +L +IQ+ER ++E LS + E+L+ E
Sbjct: 2892 KKTNTEMKDLEKQLESQNRQHEIQL-------AEIQKEREILEQLKLTLSKQKEDLEKE- 2943
Query: 1064 KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLR-NENAKLKNE 888
++ + E + L E L Q + E ++ + +DEL R N +L+N
Sbjct: 2944 RDCFEKEKADISLREELQEQS------EREGIGKTRVRIKKEMDELKQTRLNVVKELENN 2997
Query: 887 ALY-EYHDYERKNVSGSRAEAMSVL---------ISKSLGNGRANQREFQNKEED-SSGV 741
L + + ER + +AE I K N + QN+++D +
Sbjct: 2998 ELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETST 3057
Query: 740 DLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXI 561
D ++++ LE Q Q+L + E + + ++ ++ +++ L
Sbjct: 3058 DRIRDEEANLEVQKQRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQ 3117
Query: 560 RVRSLKKENTRLRSEMKGELTPSRS-FKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXX 384
+ R + ++ S+ K +L R F+ + ++ ++ + I
Sbjct: 3118 KEREILEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGID---------- 3167
Query: 383 XKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXX 204
+TRT QE+D L + + Q + +++ +++Q
Sbjct: 3168 ---NTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAEL--------- 3215
Query: 203 KWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKD 102
EK EL L E T+LKKD
Sbjct: 3216 ------KKEAEKTKLELQNERQNLEEAGTKLKKD 3243
Score = 90.9 bits (224), Expect = 2e-15
Identities = 148/726 (20%), Positives = 304/726 (41%), Gaps = 49/726 (6%)
Frame = -1
Query: 2276 EKQHTIELQENFNALRQ-KNEDICLKIEANNNLLEQKDNIIV-ELSHKLQENEEQRSALQ 2103
++ I+ ++ LR+ K + + +I ++ K +II E + ++N++ + L
Sbjct: 3562 KQNEMIDSEKKKMILREDKLQQMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMTELT 3621
Query: 2102 NDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKE 1923
+ VE TE+E L LL+ DV +L++ L + D +++ + LEN+KE
Sbjct: 3622 KQSEDVEIQMKEVLTEKELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKE 3681
Query: 1922 TVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQ--------NKQLELEIEKL- 1770
V K++ + E + +K ++ E ++ Q ++ N + EI +
Sbjct: 3682 -VLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIK 3740
Query: 1769 YGSLQMKQMENTL------LKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELA 1608
Y QMKQ ++ L +++ +++ +++ E+ +Q + KQ N+ D +
Sbjct: 3741 YQEKQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLKQSELDKQQTNMNDIIE 3800
Query: 1607 RTK-----------EVGRSATDMKKVNSDAGAKVSGILEMLLPMK--DDVFSLKEEVLGN 1467
K E+ +++K D + + E L MK VF ++ L
Sbjct: 3801 TMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVFEEEKNKLEQ 3860
Query: 1466 IN-SLRNDAQMVQVALEQMQDTKSEL---FAEAEIRAQEVLRLQAEVDAIQHILIELKRK 1299
+ L +A ++ E++Q+ + L E + + L + Q IL E+K
Sbjct: 3861 MKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVA 3920
Query: 1298 NQTLQDESQR---NAKEL-WNAKARLNNVMSKNINL---ESQNRSLKAELHLQAQKAFQI 1140
N++L E Q+ N +E+ N + +V +K NL E + L+AE+H Q + +I
Sbjct: 3921 NESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLREDELGQLQAEIHKQQR---EI 3977
Query: 1139 QEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFA 960
++E++ +ESE + VE+L+ ++ I L + E LD E+
Sbjct: 3978 EKEKSNIESERAAIIKIVEDLQHKI---------------ISLDRDAESLKLDREAFENE 4022
Query: 959 EEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQ 780
E L ++ EL +E K+K E HD + R E M+ I+K +
Sbjct: 4023 REVLKQMKTELERETDEIEKIKLET---QHDRQ-------RVEEMTAQITK-------ER 4065
Query: 779 REFQNKEEDSSGVDLLKNKCTR-LEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLS 603
+ N E+++ D++ N+ R +E +++ + +M E + ++ ++L ++++ L
Sbjct: 4066 DKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLE 4125
Query: 602 DMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTP 423
+ ++KE L + KH+E ++ + D+ T
Sbjct: 4126 KQ---------KENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTE 4176
Query: 422 L------IQXXXXXXXXXXXKIDTRTSETQEIDTLMDD-NRKYWNRVSHFTKQTQSLQNS 264
+ ++ ++D R SE + T M+D N K + ++
Sbjct: 4177 IQNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQ 4236
Query: 263 VQELQQ 246
QE+++
Sbjct: 4237 KQEMEK 4242
Score = 89.7 bits (221), Expect = 5e-15
Identities = 126/682 (18%), Positives = 290/682 (42%), Gaps = 37/682 (5%)
Frame = -1
Query: 2282 EEEKQHTI-ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
E++K++T+ E+Q+ + + NE+I ++ + EQ ++ K E ++ ++ +
Sbjct: 6121 EKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQ-------MNQKQDELDQLKTEI 6173
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
QN Q +E+ + +R + + + L ++ + + ++R ++K +++E QK
Sbjct: 6174 QNLQQELEKEKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQK 6233
Query: 1925 ETVSKELALSVSREQKLASDLKALSEKE---ESTKNQLLIQTEQNK-QLELEIEKLYGSL 1758
+ + KE + L DLK + ++ E KN+L EQ K +LE E +++
Sbjct: 6234 QEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKL----EQMKIELEREADEIRKIK 6289
Query: 1757 QMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSAT 1578
+ Q E L+ E++ + + + + +QE + K + E +A ++ +
Sbjct: 6290 EETQNERQSLEKMTEELKKEKESFTHLAEDTKKEQEILDKVKVANESLMADLQKEKSNLE 6349
Query: 1577 DMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEE---------------------VLGNIN 1461
+M++ S V E L +D+++ L+ E ++ N+
Sbjct: 6350 EMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQQREIEKEKINIESERAAIIKNVE 6409
Query: 1460 SLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQD 1281
L++ + E ++ + E E+ Q L+ E D I+ I +E + Q +++
Sbjct: 6410 DLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEE 6469
Query: 1280 ESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNV 1101
+ + K+ + K++ L +NR ++ +K IQ +++++E E +
Sbjct: 6470 MTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIE-------KKIKSIQSDKDMLEKEKHD 6522
Query: 1100 LS---SEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDE 930
L SE+ +K +L++ K+ ++ L + E + ++ + EE++ + DE
Sbjct: 6523 LEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDE 6582
Query: 929 LICLRNENAKLKNEALYEYH-------DYERKNVSGSRAEAMSVLISKSLGNGRANQREF 771
L L+ E L+ E E +R+ + + I +++ N R ++
Sbjct: 6583 LDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNER--KQLD 6640
Query: 770 QNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLS-DMX 594
++KEE ++ + ++ + L E +M + + + ++ NKLE+M+ L +
Sbjct: 6641 KDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREAD 6700
Query: 593 XXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQ 414
+ + L+K L+ E K + K RE + + E+ + +E +Q
Sbjct: 6701 DIRKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTK-REKNSLDEMKVANESSMADLQ 6759
Query: 413 XXXXXXXXXXXKIDTRTSETQE 348
I +T + ++
Sbjct: 6760 KEKSNLEEMKENISKQTEDIEK 6781
Score = 89.0 bits (219), Expect = 8e-15
Identities = 124/608 (20%), Positives = 262/608 (43%), Gaps = 47/608 (7%)
Frame = -1
Query: 2303 KEVSRLYEE-EKQHTIELQENFNALRQKNEDICLKIEANNNLLEQK---DNIIVELSHKL 2136
KE+ R +E EK E + L ++ + + LL+ K D + E+ +
Sbjct: 887 KEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLFEMDSER 946
Query: 2135 QENEEQRSALQNDMQSVEQMH-----------AVSQTEREELNR---QLVLLRDDVNHLK 1998
+E E+ R ++N+ + +EQ A Q ++EEL + QLV+ + +N +
Sbjct: 947 KELEQMRFQVENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDTESMNRSR 1006
Query: 1997 EALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLL 1818
E +A DR E + +++ Q+E V+K L + RE+ L L+ E E ++
Sbjct: 1007 E---LARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRL-LRKDMENEREDLEKIR 1062
Query: 1817 IQT-----------EQNKQLELEIEKLYGSLQM-KQMENTLLKDGNEKIYDLCKLLATKS 1674
++T E+ ++ EIE+L+ + Q E + E++ + + +
Sbjct: 1063 VETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRKMEAMKREM 1122
Query: 1673 REVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVF 1494
E++ + + KQ NI+ ++ + ++ N LEM MK D+
Sbjct: 1123 GEIEDMKVELTKQKENIDMKMEHAR--------LEMTN----------LEM---MKADLL 1161
Query: 1493 SLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILI 1314
KE++ + + +++ Q QM+ ++E+ + E +++ +AE++ +QH+
Sbjct: 1162 RQKEDIENQMLAAKSERQ-------QMEVMRTEILKQKEDVERKMELAKAEMEKMQHVKD 1214
Query: 1313 ELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQE 1134
E++++ + L++ Q+ +E+ + + K L+ + + + + +IQ
Sbjct: 1215 EIQKQRKELEERMQKTKREIGEMELMKREMEGKKKELDQRMKLTMRKKEEMERLKMEIQR 1274
Query: 1133 ERNVVE---SEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRF 963
++ +E E E+E +K+E++ ++ E + LR+ E L + E +L I
Sbjct: 1275 AKDDMEFKRVETERQKYEMEQVKAEIQRAR--EEFELRVEERDLEEEKEQMNLTI----- 1327
Query: 962 AEEKLMRILDELICLRNENAKLKNE-------ALYEYHDYERKNVSGSRAEAMSVLISKS 804
+ ++ ++ R K K + + D E N R + + +
Sbjct: 1328 -----INLIQQIEATREMVHKTKFQFENRMAGSQMGTADQEEMNAEMQRL-ILEIEHIRE 1381
Query: 803 LGNGRANQREFQNKE---EDSSGVDLLKNKCTR----LEFQVQKLSEKAEMFETKSREAQ 645
+ G + E QNKE D + LLK + R +E++ +K+ + + E S+ Q
Sbjct: 1382 MLRGLKGEVE-QNKEIMKRDREEIRLLKIEVQRRRREIEYREEKIMREQDELELMSKMGQ 1440
Query: 644 QMANKLEE 621
+ +LEE
Sbjct: 1441 RQREELEE 1448
Score = 89.0 bits (219), Expect = 8e-15
Identities = 153/839 (18%), Positives = 338/839 (40%), Gaps = 89/839 (10%)
Frame = -1
Query: 2273 KQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDM 2094
K+ LQ+ + +E + E N E + +L + +E E+ + Q++
Sbjct: 3649 KKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHER 3708
Query: 2093 QSVEQMHAVSQTERE---ELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL----QDLE 1935
Q VE+M A Q +RE ++N + D+ + ++ + D+ ++ ++ Q+LE
Sbjct: 3709 QRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQELE 3768
Query: 1934 NQKETVSK---ELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEK--- 1773
+KE + K EL L S K +++ + E ++ + QL E+ ++ + EIEK
Sbjct: 3769 KEKEIIMKDRSELDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKH 3828
Query: 1772 --------LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIE- 1620
L L+M +++ + ++ K+ + L ++ E++ +E I + ++E
Sbjct: 3829 DFDQGRNSLDEDLKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEK 3888
Query: 1619 --DELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRND 1446
+EL R KE + K + ++ E L+ S EE+ NI+ D
Sbjct: 3889 MTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTED 3948
Query: 1445 AQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDA-----------IQHILIELKRK 1299
+ + L +D +L AE + +E+ + ++ +++ +QH +I L R
Sbjct: 3949 VKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKIISLDRD 4008
Query: 1298 NQTL-----------------QDESQRNAKELWNAKA---------------------RL 1233
++L + E +R E+ K ++
Sbjct: 4009 AESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITKERDKI 4068
Query: 1232 NNVMS----KNINLESQNRSLKAELHLQAQKAFQIQEERNVVESE-HNV--LSSEVENLK 1074
NN++ K++ L +NR ++ +K IQ +++++E E HN+ SE+ +K
Sbjct: 4069 NNLIEETNRKDMVLNEKNRDIE-------EKIKSIQSDKDMLEKEKHNLEKTRSELYKVK 4121
Query: 1073 SELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLK 894
+L++ K+ ++ L + E ++++ + EE++ + DEL L+ E L+
Sbjct: 4122 EDLEKQKENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEIQNLQ 4181
Query: 893 NEALYE----YHDYERKNVSGSRAEAMSVLISKSLGNGRANQREF--QNKEEDSSGVDLL 732
E E D ++ S + ++ + + N+R+ ++KEE +
Sbjct: 4182 QELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMK-NERKLLDKDKEEMEEQKQEM 4240
Query: 731 KNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVR 552
+ + ++ ++ L E +M + + + ++ NKLE+M+ L R
Sbjct: 4241 EKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQNER 4300
Query: 551 SLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKID 372
++ T+ + + +L + RE + E+ + ++ +Q I
Sbjct: 4301 QSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRILEEMRENI- 4359
Query: 371 TRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSV-QELQQXXXXXXXXXXXXXXKWG 195
+ +T++I+ + ++ + + + Q Q+ + E
Sbjct: 4360 --SKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQNMMT 4417
Query: 194 GIDMNS--IEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEE 24
+ S +E Q+KE+ L + LKKD++ + + + LK+D E
Sbjct: 4418 ELKKKSEDVEIQMKEILTEKELLENDSNLLKKDME---DLKQKLMSIERDSESLKLDRE 4473
Score = 87.8 bits (216), Expect = 2e-14
Identities = 151/751 (20%), Positives = 299/751 (39%), Gaps = 65/751 (8%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQ--KNEDICLK--------IEANNNLLEQKDNIIV 2154
K++++ EE ++ E+++ + + Q K+ D LK IE N LEQ +
Sbjct: 4933 KQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMK---I 4989
Query: 2153 ELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVD 1974
EL + E + + QN+ Q +E+M EEL ++ KE+ + +
Sbjct: 4990 ELEKEADEIRKIKEETQNERQRLEKM-------TEELKKE-----------KESFTHLAE 5031
Query: 1973 DRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQ 1794
D +K L ++ E++ +L S +++ ++ +E E K ++ ++ ++ +Q
Sbjct: 5032 DTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQ 5091
Query: 1793 LELEIEKLYGSLQMKQMENTL--------LKDGNEKIYDLCKLLAT--KSREVQGQQEGI 1644
L+ EI K G ++M++ N +KD K++ L + L + RE + +
Sbjct: 5092 LQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREV 5151
Query: 1643 LKQ---DI-----NIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFS- 1491
LKQ D+ IE T+ + +M K++ ++E KD V +
Sbjct: 5152 LKQIKTDLKRKAEEIEKIKLETQHDRQRVEEMTAQIQKERDKINNLIEE-TNRKDMVLNE 5210
Query: 1490 LKEEVLGNINSLRNDAQMVQVALEQMQDTKSELF-AEAEIRAQEVLRL------------ 1350
+K E+ I ++ +D M++ ++ T+S+L A+ + Q ++L
Sbjct: 5211 IKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEK 5270
Query: 1349 -----QAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRS 1185
E+ I+H ++K+K QDE + E+ N + L + SQ
Sbjct: 5271 MNEKFTIEIHDIKHQEEQMKQK----QDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDL 5326
Query: 1184 LKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-KESKDLEGYFLRLFEILLG 1008
++EL Q I E + + E E K E+ KE D + L E L
Sbjct: 5327 RQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLKM 5386
Query: 1007 QHVEVASLDIESCRFAEEKL--------MRILDELICLRNENAKLKNEALYEYHDYERKN 852
++ L+ E + + K+ +R + E I +N + EAL E ER++
Sbjct: 5387 MKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKE----ERED 5442
Query: 851 VSGSRAEAMSVLISKSLGNG-------RANQREFQNKEEDSSGVDLLKNKCTRLEFQVQK 693
++ + VL + N R + +E S + ++NK L + +
Sbjct: 5443 LAEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDE 5502
Query: 692 LSE-KAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSE 516
L + +AE+ + + ++ N E + D+ SLK + +E
Sbjct: 5503 LRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENE 5562
Query: 515 MKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTL 336
K L ++ RE I++I + + D ++ +I+ ET D +
Sbjct: 5563 -KEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMV 5621
Query: 335 MDD-NRKYWNRVSHFTKQTQSLQNSVQELQQ 246
+++ NR ++ L+ +L++
Sbjct: 5622 LNEKNRDIEEKIKSIQSDKDMLEKEKHDLEK 5652
Score = 85.9 bits (211), Expect = 7e-14
Identities = 124/662 (18%), Positives = 287/662 (43%), Gaps = 38/662 (5%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIE----ANNNLLEQKDNIIVELSHKL 2136
+E ++++++ L E + E++ ++ E AN + + ++ +++EL +
Sbjct: 3234 EEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIELKKTV 3293
Query: 2135 QENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFME 1956
+ + L+N + + + V Q E + L LL+ ++ + + + E
Sbjct: 3294 TDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQLRLRE 3353
Query: 1955 KQLQDLE------------NQKETVSKELAL-----SVSREQKLASDLKALSEKE----E 1839
+L+ L+ N+K ++++ L + R Q+ + + + K+ E
Sbjct: 3354 VELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYASKDRANLE 3413
Query: 1838 STKNQLLIQTEQNKQLELEIEKLYGSLQMK-QMENTLLKDGNEKIYDLCKLLATKSREVQ 1662
K++++ Q Q+++E+ K G ++ + QM NT K+ ++K L + +E++
Sbjct: 3414 KEKSEMI---AQKHQMDIELNKERGLIEERTQMLNTYEKEMDQK----RTALEVEMKELK 3466
Query: 1661 GQQEGILKQDINIEDELARTK-EVGRSATDMKKVNS---DAGAKVSGILEMLLPMKDDVF 1494
++ I ++ +++L + K E+ R A D+KK+ + + + E L KDD+
Sbjct: 3467 YHKQAIQEE----KNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLA 3522
Query: 1493 SLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILI 1314
L E+ + R D +M + + D + E ++R + + + +D+ + +I
Sbjct: 3523 HLAED------TKRKDDEMKVLHESALADIQKEKCNLEQMR-ESMFKQNEMIDSEKKKMI 3575
Query: 1313 ELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKA-FQIQ 1137
+ K Q +Q E R E+ K+ + N + + +N+ L EL Q++ Q++
Sbjct: 3576 LREDKLQQMQAEINRQQTEMDTKKSIIEN---ERAAMTKKNQDLMTELTKQSEDVEIQMK 3632
Query: 1136 E---ERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCR 966
E E+ ++ES+ +L +VENL+ +L +++ E D E
Sbjct: 3633 EVLTEKELLESDRKLLKKDVENLQQKL---------------LIIESDSESLKQDRELLE 3677
Query: 965 FAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSR----AEAMSVLISKSLG 798
+E L ++ +L E K+K E +E E + + M+ I++ +
Sbjct: 3678 NEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIH 3737
Query: 797 NGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEM 618
+ + +++ + K+++ +D LK + L+ Q+L ++ E+ E ++L++
Sbjct: 3738 DIKYQEKQMKQKQDE---LDQLKTEIQNLQ---QELEKEKEIIMKDRSELDLKQSELDKQ 3791
Query: 617 QQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGD 438
Q ++D+ + ++K E +L + + R + + F + N D
Sbjct: 3792 QTNMNDI-------------IETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLD 3838
Query: 437 ED 432
ED
Sbjct: 3839 ED 3840
Score = 85.9 bits (211), Expect = 7e-14
Identities = 148/799 (18%), Positives = 321/799 (40%), Gaps = 47/799 (5%)
Frame = -1
Query: 2279 EEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQ------ 2118
E+++H +E + A ++N + +IE ++ + K NI E+ H+++ EEQ
Sbjct: 4560 EKERHNLEKTRSELARAKENLETQREIE-RKDIEKMKKNISREM-HEIKHQEEQMKQKQD 4617
Query: 2117 -----RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK 1953
++ +QN Q +E+ + R +L+ + L ++ + + ++R ++K
Sbjct: 4618 ELDQLKTEIQNLQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDK 4677
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALS------EKEESTKNQLLIQTEQNKQL 1791
++ E QK+ + KE + L DLK + E+E+S Q+ I+ E+
Sbjct: 4678 DKEETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVIEEEKSKLKQMKIELEREAD- 4736
Query: 1790 ELEIEKLYGSLQ------------MKQMENTLLKDGNEK--IYDLCKL-----LATKSRE 1668
EI K+ Q +K+ L +D K + D K+ LA RE
Sbjct: 4737 --EIRKVKEETQNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRE 4794
Query: 1667 ---VQGQQEGILKQDINIEDE----LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPM 1509
+Q +E I KQ ++E++ R +++ + ++ K S+ + S I +
Sbjct: 4795 RSNLQEMRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNIERERAAI 4854
Query: 1508 KDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAI 1329
DV L+ +++ SL DA+ +++ E ++ K EL Q L+ E D I
Sbjct: 4855 IKDVEDLQSKII----SLDRDAESLKLDREAFENEKEEL-------KQMKTELEREADEI 4903
Query: 1328 QHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKA 1149
+ I +E + + Q +++ + + + N + +LN ++ Q + ++ E H Q
Sbjct: 4904 EKIKLETQHERQRVEEMTADFMETMNNERKQLN---KNKEEMQEQKQEMEKERHDMDQSR 4960
Query: 1148 FQIQEERNVVESEHNVLSSE---VENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDI 978
+ + +++ + V+ E +E +K EL++ D E+ +
Sbjct: 4961 KSLDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEAD-----------------EIRKIK- 5002
Query: 977 ESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLG 798
E + ++L ++ +EL + L + E ++ V+ E++ + K
Sbjct: 5003 EETQNERQRLEKMTEELKKEKESFTHLAEDTKTEKKILDKMKVAN---ESLMADLQKEKS 5059
Query: 797 NGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEM 618
N + + EDS + K K E ++++L +AE+ + + + +N E
Sbjct: 5060 NLEEMRENISKQTEDS---EKEKEKIRLREDELEQL--QAEIHKQQGEIKMEKSNNESER 5114
Query: 617 QQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGD 438
+ D+ + SLK + +E + L ++ R+ I++I +
Sbjct: 5115 AAIIKDVKDLQHKMFSLDRDLESLKLDREAFENE-REVLKQIKTDLKRKAEEIEKIKLET 5173
Query: 437 EDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDD-NRKYWNRVSHFTKQTQSLQNSV 261
+ D ++ KI+ ET D ++++ + ++ L+
Sbjct: 5174 QHDRQRVEEMTAQIQKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEK 5233
Query: 260 QELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAW 81
+L++ ++EKQ K ++L E + K +
Sbjct: 5234 HDLEKTRSKLLRA------------KENLEKQRK------IKLAEIQKEREDLEKMNEKF 5275
Query: 80 ANSMHDLNGQEQKLKVDEE 24
+HD+ QE+++K ++
Sbjct: 5276 TIEIHDIKHQEEQMKQKQD 5294
Score = 85.1 bits (209), Expect = 1e-13
Identities = 119/600 (19%), Positives = 256/600 (42%), Gaps = 34/600 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEE 2121
E+S++ EE + L++ NAL+++ E + +I+ N +L D I V NE
Sbjct: 6964 EISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVL---DKIKV-------ANES 7013
Query: 2120 QRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDD----RAFMEK 1953
+ LQ + + +E+M RE +++Q+ +D+ + KE + D+ + ++K
Sbjct: 7014 TLADLQKEKRILEEM-------RENISKQI----EDIENEKEKSKLREDELKKLQTEVQK 7062
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTE----QNKQLEL 1785
Q +++ +K + E A + +Q + ++LK SE E ++L + E L+
Sbjct: 7063 QQSEIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKK 7122
Query: 1784 EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 1605
++E L L + ++ LK E + + + ++Q Q + I K + E R
Sbjct: 7123 DVEDLQQKLMSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQR 7182
Query: 1604 TKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVA 1425
+E A++ E + + +++ ++ + + +R + + ++
Sbjct: 7183 VEE--------------KTAQIQKEREEINTLVEEIKKKRDIIDESYTEIRKEKEAIESD 7228
Query: 1424 LEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNA 1245
++ KS+ F + + + +Q + +A++ + E+ R L+DE KE+ A
Sbjct: 7229 RSDLEKAKSQTFKQNKNIEIALAEIQQKRNALEKMSKEISRDRMKLEDEK----KEIQLA 7284
Query: 1244 KARLNNV-------------MSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHN 1104
+ L + + I ES + +AE+ LQ + + + R S+ +
Sbjct: 7285 REELERMHGDMQRQQEAKDHLLSGITDESLLKKSEAEIVLQPSQVDKAKPARKTEISDSD 7344
Query: 1103 -----VLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRI 939
V +LK LK+ + E L + +L Q ++ E+KL I
Sbjct: 7345 KQPVFVQQMPEMDLKDALKKDFESEKLDLPKVKDVLPQDQQMK---------LEQKL--I 7393
Query: 938 LDELICLRNENAKLKNEA-LYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQR---EF 771
DE+ L+ A+L+ EA E + +N + + L + N R N+ +
Sbjct: 7394 EDEMDKLKQMRAELQKEADQIEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINIQK 7453
Query: 770 QNKEEDSSGVDLLKNKCTRLEFQV----QKLSEKAEMFETKSREAQQMANKLEEMQQTLS 603
N+++ ++ + K R++ ++ ++L+++ E + E Q+ LEEM+ +S
Sbjct: 7454 VNQQKQATAFQMEKTDFERIKTEIDQANKELADQQEKNKKTITEMQKERETLEEMRANIS 7513
Score = 85.1 bits (209), Expect = 1e-13
Identities = 120/621 (19%), Positives = 270/621 (43%), Gaps = 60/621 (9%)
Frame = -1
Query: 2279 EEKQH-TIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIV----ELSHKLQENEEQR 2115
++K+H T E ++ + ++ KI+ LE++ ++ L+ L+E + Q+
Sbjct: 10181 DKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQIEAENLNKVLEEIKRQQ 10240
Query: 2114 SALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLE 1935
L+ ++ M + REE R+ + + + + + A + +R ++KQ Q+L+
Sbjct: 10241 EKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQKQELQ 10300
Query: 1934 NQKETVSKELALSVSREQKLASDLKALSEKE---ESTKNQLLIQTEQNKQLELEIEKLYG 1764
Q + + + ++ + + ++L E++ E N++L Q + ++ + ++ K +
Sbjct: 10301 KQADDLDMRM---IAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWN 10357
Query: 1763 SLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRS 1584
L + Q E +++ N+ + ++ E+ G++ I K+ +E+ L + +
Sbjct: 10358 KLDVLQNE---MQNENKAMEEI-------KYELDGKRNEINKEQQRLEESL---RAINEE 10404
Query: 1583 ATDMKKVNSDAGAKVSGILEM----------LLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
D++ + +D + I EM L +K ++ K E+ L ND M+
Sbjct: 10405 KGDLEIMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMI 10464
Query: 1433 Q--------------VALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIEL---- 1308
+ +QM+D +SEL + + E +++ + ++ ++ E+
Sbjct: 10465 EKERNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQR 10524
Query: 1307 ---KRKNQTLQDESQRNAKE---LWNAKARLNNVMSKNINLE----SQNRSLK-AELHLQ 1161
K K + L E Q E L + L N + N+E ++ +LK E HLQ
Sbjct: 10525 NDFKLKKEELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQ 10584
Query: 1160 AQK--AFQIQEERNVVESEHNVLSSEVENLKSELKESKD-LEGYFLRLFEILLGQHVEVA 990
K I EE + + + +S+ + K ELK KD LE + +
Sbjct: 10585 RDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRID 10644
Query: 989 SLDIESCRFAEEKL---MRILDELICLRNENAK---LKNEALYEYHDYERKNVSGSRAEA 828
D + + EE L ++ +E CL N K +K +A E+H+ +K + +
Sbjct: 10645 EFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQK-IEELQTLQ 10703
Query: 827 MSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREA 648
++ K + + + ++ D +L++ K T ++ + +KL++ +M E + +
Sbjct: 10704 EQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREK-TEVDHEQKKLNDDIKMIEQEKEDL 10762
Query: 647 QQMANKL----EEMQQTLSDM 597
++M +++ +EM++ S++
Sbjct: 10763 EKMKSEIMTQKQEMEKERSEL 10783
Score = 85.1 bits (209), Expect = 1e-13
Identities = 116/634 (18%), Positives = 264/634 (41%), Gaps = 36/634 (5%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
K S + ++ +Q E E N +RQ + C IE + ++++ + E H++Q +
Sbjct: 12156 KMKSEIMKQRQQMEEERSELENKIRQTYIEKC-DIENSKEIVQKLMVEVEEQKHEIQFQK 12214
Query: 2123 EQ------------------RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLK 1998
E+ +S LQN+ + ++ ++ V + ERE L L + +K
Sbjct: 12215 EELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMK 12274
Query: 1997 EALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLL 1818
+ +EK + QK+ + + L +++ K L ++ + Q+
Sbjct: 12275 SITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVS 12334
Query: 1817 IQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILK 1638
Q E++ E E+++ SL+ + +K E +E + ++E +
Sbjct: 12335 KQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEP--------EEIKKEKEKEEE---E 12383
Query: 1637 QDINIEDELARTKEVGRSATDMKKVNSDAG---AKVSGILEMLLPMKDDVFSLKEEVLGN 1467
Q++ ++ E+ R KE+ + + +++V S+ K++ +M+ K+D+ +K E++
Sbjct: 12384 QEMRVKVEMER-KEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQ 12442
Query: 1466 INSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTL 1287
+ + + ++Q K ++ EI + ++ ++ + IQ EL + Q +
Sbjct: 12443 RQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKI 12502
Query: 1286 QDESQ---RNAKELWNAKARLNNVMSKNINLESQN-RSLKAELHLQAQKAFQIQEERNVV 1119
DE +N E N R+ M + I E + + ++ L + ++ + EE
Sbjct: 12503 ADEQDLLIQNKIEQQNENERIKE-MDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRR 12561
Query: 1118 ESEHNVLSSEVENLKSELKESKDL---EGYFLRLFEILLGQHVE--------VASLDIES 972
+ + +S+++ K +L +DL E + L Q ++ + + +E
Sbjct: 12562 KEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEE 12621
Query: 971 CRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNG 792
+EKL + + E + E + + E D ++N E M L+ K +
Sbjct: 12622 KTEMDEKLQQAIKEYESIIEETNRKRTELEEIEVDQSQQN---KNVETMKDLLEKERKDT 12678
Query: 791 RANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQ 612
+ E Q K+ D + ++++ + E + L E+ ++ E K+ E + + LE+ ++
Sbjct: 12679 EKEREELQ-KQADDLEMQMIEHG-DKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKE 12736
Query: 611 TLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK 510
DM +++ K E ++ E++
Sbjct: 12737 ---DMMKKWNELDGLQKEIQNQKNEMEEIKCELE 12767
Score = 84.3 bits (207), Expect = 2e-13
Identities = 147/702 (20%), Positives = 294/702 (41%), Gaps = 78/702 (11%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQEN---FNALRQKNEDICLKIEANNNLLE------QKDNIIVE 2151
+EV +E +Q T +L+E+ F+ ++KN I +I+ ++ LE K+ I E
Sbjct: 2208 QEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTIFE 2267
Query: 2150 LSHK---LQENE-----EQRSALQNDMQ----SVEQMHAVSQTER--------------- 2052
L + L+ENE +Q LQN ++ VEQM A +R
Sbjct: 2268 LEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTARGRETT 2327
Query: 2051 --EELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQK 1878
EE +++ LR++ ++++ + + E +++ LE + E + K+ + +E +
Sbjct: 2328 ALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAM-KKYKEKLDKEYE 2386
Query: 1877 LASDLKALSEKE-ESTKNQLLIQTE--QNKQLELEIEK--LYGSLQMKQMENTLL-KDGN 1716
+ L EKE + + +L I+ E + K+ ELEI+K +Y M + + ++ K
Sbjct: 2387 DLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKT 2446
Query: 1715 EKIYDLCKLLATKSREVQGQQEGILKQDINI-EDELARTKEVGRSATDMKKVN---SDAG 1548
+++ ++ K + EV+ Q+ +++ ++ I ++E KE R + N S
Sbjct: 2447 DELDEVRKKINADLSEVEKQKSALVQMNLKISQEESYVKKEKDRLKLQENEQNMQMSQLN 2506
Query: 1547 AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRA 1368
AK + + E M+ L E V+ + + + + + +MQ+ A ++
Sbjct: 2507 AKQNELDERQAEMEKQKREL-ENVMDRLEKEKVEITKEKQRVNEMQNEVKRKNASVDLIK 2565
Query: 1367 QEVLRLQAEVDAIQHI----LIELKRKN-------QTLQDESQRNAKELWNAKARLNNVM 1221
QEVLR Q ++ + I L ++K K + L D+ + KE+ +
Sbjct: 2566 QEVLREQDHIENSREILNRELEKIKEKKTILAEEFEALDDKKEMIGKEMQRLGKMKAELQ 2625
Query: 1220 SKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-------- 1065
+ + E Q R + + + ++Q E+ +E+ + + E NL+ +
Sbjct: 2626 KEAEDTEKQRRDIDNDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLESDRD 2685
Query: 1064 ---KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLK 894
KE DLE + + L + +E S E +K IL++ L+ +K K
Sbjct: 2686 TLEKERFDLEKTKTEMKD--LEKQLESQSRQHEIQLVEIQKEREILEQ---LKINLSKQK 2740
Query: 893 NEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEE-DSSGVDLLKNKCT 717
+ E +E++ S E + K G + R Q +E + + ++++K +
Sbjct: 2741 EDLEKERDCFEKEKADISLREELEEQSEKE-GIDKTRVRIKQEMDELEQTRLNVVK-ELE 2798
Query: 716 RLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTL-SDMXXXXXXXXXXXIRVRSLKK 540
E Q Q + ++ + E E Q+ A E+ +Q + +D + ++
Sbjct: 2799 NNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIET 2858
Query: 539 ENTRLRSE------MKGELTPSRSFKHREGSFIKEINIGDED 432
R+R E +K L R +E +K+ N +D
Sbjct: 2859 STDRIRDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEMKD 2900
Score = 84.3 bits (207), Expect = 2e-13
Identities = 158/788 (20%), Positives = 326/788 (41%), Gaps = 59/788 (7%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNII----VELSHKLQENEEQR 2115
EE+KQ + ++N + R+ ++ K++ + E++ N + +EL + E + +
Sbjct: 5774 EEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIK 5833
Query: 2114 SALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLE 1935
QN Q +E+M EEL R+ KE+L+ +D +K L +++
Sbjct: 5834 EETQNKRQRLEKM-------TEELIRE-----------KESLAHLAEDTKTEKKILDEMK 5875
Query: 1934 NQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQ 1755
E+ +L S +++ ++ L E ++ K + ++ ++ K+L+ E++K +
Sbjct: 5876 VANESSMADLQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKID 5935
Query: 1754 MKQ--MENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSA 1581
M++ +E+ EK ++ L KS +V+ Q + IL E EL
Sbjct: 5936 MEKTNIESERAAMIREK-QNMMTELKKKSEDVEIQMKEIL-----TEKELLH-------- 5981
Query: 1580 TDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQM---VQVALEQMQ 1410
D K + D V + + L+ ++ D LK + N QM +Q+ ++++
Sbjct: 5982 NDRKLLTRD----VENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEIE 6037
Query: 1409 DTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLN 1230
K E + + + ++Q E D I +++ E RK+ L ++++ +++ + ++ +
Sbjct: 6038 KIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKD 6097
Query: 1229 NVMSKNINLESQNRSL-KAELHLQAQK---AFQIQEERNVVE------------------ 1116
+ + NLE L K + L+ QK +IQ+ER VE
Sbjct: 6098 MLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEE 6157
Query: 1115 ------SEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAE- 957
E + L +E++NL+ EL++ K++ F++ + LD + +
Sbjct: 6158 QMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQFDL------RQSELDKQQTNMNDI 6211
Query: 956 -EKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQ 780
E + +L + E + K E E HD+++ S + + + + K + N+
Sbjct: 6212 METMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDK-DLKMMKLQKQVFEEEKNK 6270
Query: 779 REFQNKEEDSSGVDLLK------NKCTRLEFQVQKLSEKAEMF---ETKSREAQQMANKL 627
E E + ++ K N+ LE ++L ++ E F +++ Q++ +K+
Sbjct: 6271 LEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFTHLAEDTKKEQEILDKV 6330
Query: 626 E--------EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHRE 471
+ ++Q+ S++ V + KKEN RLR + +L + RE
Sbjct: 6331 KVANESLMADLQKEKSNLEEMRENISKQTEDVEN-KKENLRLREDELWQLQAEIYKQQRE 6389
Query: 470 GSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFT 291
I++ I E + I +D R SE+ ++D R+ +
Sbjct: 6390 ---IEKEKINIESERAAIIKNVEDLQHKIISLD-RDSESLKLD------REAFENEREVL 6439
Query: 290 KQTQS-LQNSVQELQQXXXXXXXXXXXXXXKWGGI--DMNSIEKQLKELNIHVMQLVEHN 120
KQ ++ L+ E+++ I D + I ++E N M L E N
Sbjct: 6440 KQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKN 6499
Query: 119 TRLKKDVK 96
++K +K
Sbjct: 6500 RDIEKKIK 6507
Score = 84.0 bits (206), Expect = 3e-13
Identities = 140/786 (17%), Positives = 327/786 (41%), Gaps = 26/786 (3%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQ-----ENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHK 2139
+E + EE K IE++ E ++K E+ ++ + E+ D I +L
Sbjct: 11793 EEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKK-EELDQIKSQLERV 11851
Query: 2138 LQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFM 1959
E + ++ L +D + +EQ + + E+ +Q + ++ + L + +R
Sbjct: 11852 RSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLER--- 11908
Query: 1958 EKQLQDLENQKETVSKELA--------LSVSREQKLASDLKALSEKEESTKNQLLIQTEQ 1803
D+EN KE V K + + + +E+ K E+ +N+ +Q E
Sbjct: 11909 ----HDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNEN 11964
Query: 1802 NKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQD--- 1632
+ E++ E +K+ME L K+ E + + + +++ + KQ+
Sbjct: 11965 ERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDL 12024
Query: 1631 INIEDELARTK-EVGRSATDMKKVNSDAGAKVSGILEMLL----PMKDDVFSLKEEVLGN 1467
+N D L + + E+ T +++ + A+VS E L M+++ SL+E +
Sbjct: 12025 MNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKI-K 12083
Query: 1466 INSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTL 1287
I ++ + ++ E+ ++ + + A+ E++ +E+ +++++++ ++ E+ + + L
Sbjct: 12084 IIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRS---EIDHEQKKL 12140
Query: 1286 QDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEH 1107
D+ + +E + + + +M + +E + L+ ++ + I+ + +V+
Sbjct: 12141 NDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQK-- 12198
Query: 1106 NVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL 927
L EVE K E++ K+ LDIE + A+E+ + I ++
Sbjct: 12199 --LMVEVEEQKHEIQFQKE--------------------ELDIERQKIADEQDLLIQNKS 12236
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSS 747
L+NEN ++KN + E ER+ + + M + K ++ E + ++ED
Sbjct: 12237 E-LQNENERIKN--INEVIKKERETL-----KEMEAYLEKEKEEMKSITEETRRQKED-- 12286
Query: 746 GVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXX 567
L+ T + Q Q L + ++ E +E +++ +K +++QQ + +
Sbjct: 12287 ----LEKMSTHINEQKQDLRSQRDLLE---QEREEINHKWKQLQQRIDEFDAQVSKQKEE 12339
Query: 566 XIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXX 387
+ KE+ + E K + ++ E IK+ +E++ Q
Sbjct: 12340 DLPKEKEMKEDRKSLEETKANILEMKT--KAEPEEIKKEKEKEEEE----QEMRVKVEME 12393
Query: 386 XXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQ-TQSLQNSVQELQQXXXXXXXXXXXX 210
+I+ S+ + + + MD +K N +Q + L+ E+ +
Sbjct: 12394 RKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMK------------ 12441
Query: 209 XXKWGGIDMNSIEKQLKELNIHVMQ--LVEHNTRLKKDV--KFGFAWANSMHDLNGQEQK 42
+E++ EL+ + Q L +H+ K++ K H++ Q+++
Sbjct: 12442 -------QRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEE 12494
Query: 41 LKVDEE 24
L ++ +
Sbjct: 12495 LDIERQ 12500
Score = 83.6 bits (205), Expect = 4e-13
Identities = 153/813 (18%), Positives = 320/813 (39%), Gaps = 62/813 (7%)
Frame = -1
Query: 2276 EKQHTI---ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSAL 2106
EKQ I E+Q+ L + NE ++I + EQ + K E ++ ++ +
Sbjct: 5251 EKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQ-------MKQKQDELDQLKTEI 5303
Query: 2105 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 1926
QN Q +E+ + +R +L+ + L ++ + + ++R ++K ++ E QK
Sbjct: 5304 QNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQK 5363
Query: 1925 ETVSKELALSVSREQKLASDLKALS------EKEESTKNQLLIQTEQN----KQLELEI- 1779
+ + KE + L DLK + E E+S Q+ I+ E+ ++++ EI
Sbjct: 5364 QEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQ 5423
Query: 1778 ------EKLYGSLQMKQMENTLLKDGNEKIYD---------LCKLLATKSREVQGQQEGI 1644
EK+ +L+ ++ + N ++ D L +L KS ++ +E I
Sbjct: 5424 NERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKS-NLEEMRENI 5482
Query: 1643 LKQDINIEDE----LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEV 1476
KQ ++E++ R E+ + ++ K + + I + DV L+ ++
Sbjct: 5483 SKQTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKI 5542
Query: 1475 LGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKN 1296
+ L DA+ +++ E ++ E E+ Q L+ E D I+ I +E +
Sbjct: 5543 I----CLDRDAESLKLDREAFEN-------EKEVLKQMKTELEREADEIEKIKLETQHDR 5591
Query: 1295 QTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVE 1116
Q +++ + + K+ + K++ L +NR ++ +K IQ +++++E
Sbjct: 5592 QRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIE-------EKIKSIQSDKDMLE 5644
Query: 1115 SEHNVLS---SEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLM 945
E + L SE+ +K +L++ K+ ++ L + E + ++ + EE++
Sbjct: 5645 KEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMN 5704
Query: 944 RILDELICLRNENAKLKNEALYE----YHDYERKNVSGSRAEAMSVLISKSLGNGRANQR 777
+ DEL L+ E L+ E E D + ++ S + ++ + + ++
Sbjct: 5705 QKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERK 5764
Query: 776 EF--------QNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLE- 624
+ + K+E D + L+ +K+ + +MFE + + +QM +LE
Sbjct: 5765 QLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELER 5824
Query: 623 -------------EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSF 483
+Q L M + K ++ EMK S +
Sbjct: 5825 EADEISKIKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMAD 5884
Query: 482 KHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRV 303
RE S ++E+ I ++ +E Q+ + +D + N
Sbjct: 5885 LQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKT--NIE 5942
Query: 302 SHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEH 123
S + QN + EL++ +E Q+KE+ L
Sbjct: 5943 SERAAMIREKQNMMTELKK-------------------KSEDVEIQMKEILTEKELLHND 5983
Query: 122 NTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEE 24
L +DV+ + DL ++LK+D E
Sbjct: 5984 RKLLTRDVE---NLQQKLIDLERDSKRLKLDRE 6013
Score = 83.6 bits (205), Expect = 4e-13
Identities = 128/620 (20%), Positives = 275/620 (44%), Gaps = 63/620 (10%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLE-QKDNIIVELSHKLQEN 2127
+E S L ++ KQ +E + N+ ++ E + +++E + ++ QK+ + +E E
Sbjct: 12448 EERSELDKKIKQTDLEKHDIENS-KEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQ 12506
Query: 2126 E---EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFME 1956
+ + + QN+ + +++M + ERE L V L+ + ++ + + +E
Sbjct: 12507 DLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLE 12566
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSEK--EESTKNQLLI------QTEQN 1800
K D+ QK+ + + L +++ L L ++ E T + +L+ +TE +
Sbjct: 12567 KMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMD 12626
Query: 1799 KQLELEIEKLYGSLQMKQMENTLLKD-------GNEKIYDLCKLLATKSREVQGQQEGIL 1641
++L+ I++ ++ + T L++ N+ + + LL + ++ + ++E +
Sbjct: 12627 EKLQQAIKEYESIIEETNRKRTELEEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQ 12686
Query: 1640 KQDINIEDELAR---TKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLG 1470
KQ ++E ++ +E+ + + D +K + A +L +DD+ KE+++
Sbjct: 12687 KQADDLEMQMIEHGDKEEMSKRSLDEEKKLLEQKANE------ILRQRDDLEKEKEDMMK 12740
Query: 1469 NINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAI------------- 1329
N L + +Q +M++ K EL + +E RL+ ++ +
Sbjct: 12741 KWNELDGLQKEIQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLEIVRVD 12800
Query: 1328 ----QHILIELKRKNQTLQDE-SQRNAKELWNAKARLNNVMSKNI------NLESQNRSL 1182
Q + E++ K + +DE Q AK L + K N SK++ +E +L
Sbjct: 12801 YEKHQQQIEEMRVKTKMERDELDQLMAKMLMDRK---ENERSKDMIGLLKKEMEQTKFNL 12857
Query: 1181 KA---ELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILL 1011
A EL L+ QK +++ + ++E +SEV+ LK + E KD + + E L
Sbjct: 12858 DAQEEELKLEKQKIQNEKKDLEMFKAEIKREASEVKTLKEQQLE-KDTKAFEALKEEHLP 12916
Query: 1010 GQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKL-KNEALYEYHDYERKNVSGSR- 837
GQ V+ + E + E K RIL E + E +L +N+ + E+ + +
Sbjct: 12917 GQFVQQKGGEFERIQIDEVK--RILSE---IHKEKKELERNKQILEHQREALLEIKSKQP 12971
Query: 836 AEAMSVLISKS---------LGNGRANQREFQNKEEDSSGVDLLKNKCTRL---EFQVQK 693
+E + V++ S + + A+Q E K D++K T + E+++ K
Sbjct: 12972 SERLDVILVSSATQTSDLEDIPDVSASQGETVEKH-----TDIIKEYTTSIPKEEYEIDK 13026
Query: 692 LSEKAEMFETKSREAQQMAN 633
L ++ + +RE +MA+
Sbjct: 13027 LKQQGDKKLKSTREDTKMAD 13046
Score = 83.6 bits (205), Expect = 4e-13
Identities = 137/665 (20%), Positives = 282/665 (42%), Gaps = 98/665 (14%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNI---IVELSHKLQE 2130
E+ +L ++ ++ EL++ L+++ + KI+A Q D I I L + +E
Sbjct: 13400 EIQKLRKQYEKEKCELEQIKPDLQKREPE---KIDAE----VQHDEIHGGIDSLKEEREE 13452
Query: 2129 NEEQRSALQNDMQSVEQMHAVSQTEREELNR------QLVL----------LRDDVNHLK 1998
E+ ++ LQN ++ E M + + E++EL + Q+ + L+D++ ++
Sbjct: 13453 IEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIE 13512
Query: 1997 EALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKA-----LSEKEEST 1833
L + + ++E+ ++L +K + + + +L +K +S+ EE
Sbjct: 13513 AILKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKMEERE 13572
Query: 1832 KNQLLIQ------TEQNKQLELEIEKLYG-SLQMKQMENTLLKDGNEKIYDLCKLLATKS 1674
+ I+ E++++++ E E+L ++K+ L + NE + K
Sbjct: 13573 AERKTIERVMDEMAEEHEKIKKEREELVNMEEEIKKQRRVLEESMNE--------MTKKK 13624
Query: 1673 REVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGIL----EMLLPMK 1506
E+Q ++ + KQ +ED +A S D+ S + IL E + MK
Sbjct: 13625 SELQHERSELYKQKQQLEDMIA-----SESKRDVDTERSRQDKEDEQILKREREEIADMK 13679
Query: 1505 DDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSE--------LFAEAEIRA------ 1368
D + KE+V + + + ++ Q+ D K E L+ + EI+
Sbjct: 13680 DQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEIQVKTNALE 13739
Query: 1367 ---QEVLRLQAEVDA--IQH---------ILIELKRKNQTLQDESQRNAKELWNAKARL- 1233
Q++ + + V+A IQH ++ E KRK + + E QR +++ + K RL
Sbjct: 13740 KMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFEDIESVKVRLV 13799
Query: 1232 ---NNVMSKNINLESQNRSLKAELHLQAQKAF-----QIQEERNVVESEHNVLSSEVENL 1077
N + N L++++ L+ L + QK F ++Q ER +E + L + L
Sbjct: 13800 TESNQIDKMNSELKTRSEELE-NLIKKQQKEFETKENEMQRERKALEKMNAELERKSTEL 13858
Query: 1076 KSELKE----SKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEK---------LMRIL 936
K+++++ DL+ + E+ E + L E + ++K + +
Sbjct: 13859 KNKIEKVTVWEADLQKEKNKTEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEM 13918
Query: 935 DELICLRNENAKLKNEAL----YEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQ 768
+ L CLRNE K L E H+ ++ ++E S+ K ++ E +
Sbjct: 13919 ENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTE-IQSEKESIEEEKKTLKQLKDENESK 13977
Query: 767 NKEEDSSGVDLLKNKCTRLEFQVQK---------LSEKAEMFETKSREAQQMANKLEEMQ 615
+ D++ + K +L Q +K L KAE + + R+A Q+ +++ +
Sbjct: 13978 RTQLDNT---IEKMNMDKLSIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDA 14034
Query: 614 QTLSD 600
+ L D
Sbjct: 14035 KILDD 14039
Score = 81.6 bits (200), Expect = 1e-12
Identities = 148/839 (17%), Positives = 336/839 (40%), Gaps = 86/839 (10%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNII----VELSHKLQENEEQR 2115
EE+K+ + + +F+ R ++ ++ + E++ N + +EL + E + +
Sbjct: 3817 EEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIK 3876
Query: 2114 SALQNDMQSVEQM------------HAVSQTER--------------------------E 2049
+QN+ QS+E+M H T++ E
Sbjct: 3877 EEIQNERQSLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEKSNFE 3936
Query: 2048 ELNRQLVLLRDDVNHLKEALSMAVDD----RAFMEKQLQDLENQKETVSKELALSVSREQ 1881
E+ + +DV + KE L + D+ +A + KQ +++E +K + E A + +
Sbjct: 3937 EMRENISKQTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVE 3996
Query: 1880 KLASDLKALSEKEESTK-NQLLIQTEQN--KQLELEIEKLYGSLQMKQMENTLLKDGNEK 1710
L + +L ES K ++ + E+ KQ++ E+E+ ++ ++E + ++
Sbjct: 3997 DLQHKIISLDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLET---QHDRQR 4053
Query: 1709 IYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGI 1530
+ ++ + + ++ E ++D+ + ++ +E +S K + +
Sbjct: 4054 VEEMTAQITKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKT 4113
Query: 1529 LEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRL 1350
L +K+D+ KE L I R D LE+M + + E + + +++ +
Sbjct: 4114 RSELYKVKEDLEKQKENTLAEIQKERED-------LEKMNENITIEMHEIKHQEEQMKQK 4166
Query: 1349 QAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAEL 1170
Q E+D ++ E++ Q L+ E + K+ R + + + N+ ++K E
Sbjct: 4167 QDELDQLK---TEIQNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNER 4223
Query: 1169 HLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESK------DLEGYFLRLFEILLG 1008
L + +++E++ +E E + + +++L +LK K + E L + L
Sbjct: 4224 KLLDKDKEEMEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQ 4283
Query: 1007 QHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEA 828
+ + E + + L ++ LI R + L E + V+ + A
Sbjct: 4284 READEIRKIKEETQNERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMA 4343
Query: 827 MSVLISKSLGNGRAN-QREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETK--- 660
+ L R N ++ ++ E + L +++ +L+ +VQK + +M +T
Sbjct: 4344 DLQREKRILEEMRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIES 4403
Query: 659 -----SREAQQMANKLEEMQQTLS-DMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELT 498
RE Q M +L++ + + M LKK+ L+ ++
Sbjct: 4404 ERAVMIREKQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLMSIER 4463
Query: 497 PSRSFKHREGSFIKEINIGDEDDTPL------IQXXXXXXXXXXXKIDTRTSETQ----E 348
S S K +F E + + T L I+ +++ +T++ Q E
Sbjct: 4464 DSESLKLDREAFGNEKEVLKQMKTDLQIQADEIEKIKLETQHDRQRVEEKTAQIQKDRDE 4523
Query: 347 IDTL-MDDNRK--YWNRVSH-FTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMN 180
I+ L ++ NRK N + ++ +S+Q+ L++ + +
Sbjct: 4524 INNLIVETNRKDMVLNEMDRDIEEKIKSIQSDKDMLEK-------------------ERH 4564
Query: 179 SIEKQLKEL-----NIHVMQLVEHN--TRLKKDVKFGFAWANSMHDLNGQEQKLKVDEE 24
++EK EL N+ + +E ++KK++ + MH++ QE+++K ++
Sbjct: 4565 NLEKTRSELARAKENLETQREIERKDIEKMKKNI------SREMHEIKHQEEQMKQKQD 4617
Score = 79.7 bits (195), Expect = 5e-12
Identities = 114/611 (18%), Positives = 267/611 (43%), Gaps = 43/611 (7%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
K S L + +Q E E +++ N + KIE N ++E+ + E + + +
Sbjct: 10473 KMKSELMTQRQQMEDERSELDQKIKEANTEKD-KIEKNKEIVERLMAEVEEQRNDFKLKK 10531
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNH----LKEALSMAVDDRAFME 1956
E+ + + ++ + + A +TE + + Q+ + + V + LKE + D+ ++
Sbjct: 10532 EELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIK 10591
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQ-----NKQL 1791
+++ QKE + K ++ ++ +++ + K E+E N Q +Q + Q+
Sbjct: 10592 SIIEETSRQKEDLEK-ISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQV 10650
Query: 1790 ELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKL-------LATKSREVQGQQEGILKQD 1632
+ E+ + + + E L++ N KI ++ + K E+Q QE I+K+
Sbjct: 10651 RKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEK 10710
Query: 1631 INIEDELARTKEVGRSATDMKKVNSD----------AGAKVSGILEMLLPMKDDVFSLKE 1482
E A T ++ D+ ++ S+ K++ ++M+ K+D+ +K
Sbjct: 10711 EKAE---AMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKS 10767
Query: 1481 EVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKR 1302
E++ + + + ++Q K ++ EI + + ++ + IQ EL
Sbjct: 10768 EIMTQKQEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDI 10827
Query: 1301 KNQTLQDESQ---RNAKELWNAKARLNNVMSKNINLESQNRSLK-AELHLQAQKAFQIQE 1134
+ Q + DE +N EL N R+ N+ N ++ + +LK E HL+ +K E
Sbjct: 10828 ERQKIADEQDLLIQNKSELQNENERIRNI---NEVIKKERETLKEMEAHLEKEK-----E 10879
Query: 1133 ERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEE 954
E + E ++E + +++KE + L+ Q ++ + E
Sbjct: 10880 EMKSITEETRRQKEDLEKMSTDIKEQN----------QDLMKQR-DLLEQEKEDINHEWT 10928
Query: 953 KLMRILDELICLRNENAKLKNEALYEYHDY--ERKNVSGSRAEAMSVLISKSLGNGRANQ 780
+L + +DE + +K K E L + + ERK++ ++A + + L + + +
Sbjct: 10929 QLQQRIDEFDA---QVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEK 10985
Query: 779 REFQNKEE-------DSSGVDLLKNKCTR----LEFQVQKLSEKAEMFETKSREAQQMAN 633
+ + +EE D +D +K++ R ++ + +KL++ ++ E + + ++M +
Sbjct: 10986 EKEEEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKS 11045
Query: 632 KLEEMQQTLSD 600
++ + +Q + +
Sbjct: 11046 EIMKQRQQMEE 11056
Score = 79.7 bits (195), Expect = 5e-12
Identities = 106/593 (17%), Positives = 267/593 (45%), Gaps = 25/593 (4%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLE-QKDNIIVELSHKLQEN 2127
+E S L + KQ IE + N+ ++ + + +++E + ++ QK+ + +E E
Sbjct: 11056 EERSELENKIKQTYIEKCDIENS-KEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQ 11114
Query: 2126 E---EQRSALQNDMQSVEQMHAVSQTERE---ELNRQLVLLRDDVNHLKEALSMAVDDRA 1965
+ + +S LQN+ + + ++ + + ERE E+ L ++++ + E +D
Sbjct: 11115 DLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRLKED-- 11172
Query: 1964 FMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLEL 1785
+EK D+ Q + + + L +++ K L ++ + Q+ Q EQ+ E
Sbjct: 11173 -LEKMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEK 11231
Query: 1784 EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 1605
+++ SL+ + +K E K +E + ++E +++I + E R
Sbjct: 11232 GMKEDRKSLEETKANVIEMKTKAEPEE------IKKEKEKENEEEEEEEEEIRVIVETER 11285
Query: 1604 TKEVGRSATDMKKVNSDAG---AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
KE+ + +++++V S+ K++ ++M+ K+D+ +K E++ + + +
Sbjct: 11286 -KELYQIKSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSEL 11344
Query: 1433 QVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQ---RNA 1263
++Q K ++ EI + ++ ++ + IQ EL + Q + DE +N
Sbjct: 11345 DNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQNK 11404
Query: 1262 KELWNAKARLNNVMSKNINLESQNRSLK-AELHLQAQKAFQIQEERNVVESEHNVLSSEV 1086
+L N R+ V + ++ + +L+ E+HL+ +K +E R+++E E ++
Sbjct: 11405 AKLQNENERIKKV---DEEIKKERETLREMEIHLKKEK----EELRSIIE-ETQRRKEDL 11456
Query: 1085 ENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNEN 906
E + +++ E K + L ++ + E +L + +DE +
Sbjct: 11457 EKMSTDINEQK-----------LHLKNQRDLLEQEREEINHEMTQLQQRIDEFDA---QV 11502
Query: 905 AKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDL--- 735
+K + + + + ERK++ ++A + + L ++E +++EE V++
Sbjct: 11503 SKQREDLTKQEMEEERKSLEETKARIIEMKTKAEL-QEIMQEKEEEDEEEMRVIVEMERE 11561
Query: 734 --------LKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSD 600
LK + ++ + +KL++ ++ E + + ++M +++ +Q + +
Sbjct: 11562 ELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEE 11614
Score = 77.4 bits (189), Expect = 3e-11
Identities = 122/621 (19%), Positives = 274/621 (44%), Gaps = 65/621 (10%)
Frame = -1
Query: 2273 KQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQ-ENEEQRSALQND 2097
KQ EL++ L ++ E+ E ++E + + I ++ +L+ E E+ + LQN+
Sbjct: 3174 KQEMDELEKTRQNLAKEQENN----ELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNE 3229
Query: 2096 MQSVEQMHAVSQTER-------EELNRQLVLLRD-----DVNHLKEALSMAVDDRAFME- 1956
Q++E+ + +R EEL R+ V+L + ++ + + +R +E
Sbjct: 3230 RQNLEEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIEL 3289
Query: 1955 -KQLQDLENQKETVSKELALSVSREQKLASDLKALSE-----KEESTKNQLLI--QTEQN 1800
K + D+ KE + +L + + ++++A + K+ ++ Q+ I +TEQ
Sbjct: 3290 KKTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQL 3349
Query: 1799 KQLELEIEKLYGSLQMKQMENTLLKDGNEK--IYDLCKLLATKS------REVQGQQEGI 1644
+ E+E+E+L + +Q E + N K I + +L K+ REV E
Sbjct: 3350 RLREVELEQLQALIYRQQDE----IEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYA 3405
Query: 1643 LKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNI 1464
K N+E E +++ + + ++N + G + +ML + ++ + + +
Sbjct: 3406 SKDRANLEKE--KSEMIAQKHQMDIELNKERGL-IEERTQMLNTYEKEMDQKRTALEVEM 3462
Query: 1463 NSLRNDAQMVQVALEQMQDTKSELFAEAE--IRAQEVLR------------LQAEVDAIQ 1326
L+ Q +Q ++Q K EL EA+ + +E R L+ E D +
Sbjct: 3463 KELKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLA 3522
Query: 1325 HILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAF 1146
H+ + KRK+ ++ + ++ K L + S K ++ L+ K
Sbjct: 3523 HLAEDTKRKDDEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQ 3582
Query: 1145 QIQEE-----------RNVVESEHNVLSSEVENLKSEL-KESKDLEGYFLRLFEILLGQH 1002
Q+Q E ++++E+E ++ + ++L +EL K+S+D+E +++ E+L +
Sbjct: 3583 QMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVE---IQMKEVLTEKE 3639
Query: 1001 V-----EVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSR 837
+ ++ D+E+ ++KL+ I + L+ + L+NE E + ++ G
Sbjct: 3640 LLESDRKLLKKDVEN---LQQKLLIIESDSESLKQDRELLENEK--EVLKQMKTDLQGEA 3694
Query: 836 AEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTR----LEFQVQKLSEKAEMF 669
E + + R + Q ++D + + + TR +++Q +++ +K +
Sbjct: 3695 EEIEKIKLETQHERQRVEEMTAQ-IQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDEL 3753
Query: 668 ETKSREAQQMANKLEEMQQTL 606
+ E Q + +LE+ ++ +
Sbjct: 3754 DQLKTEIQNLQQELEKEKEII 3774
Score = 77.0 bits (188), Expect = 3e-11
Identities = 132/656 (20%), Positives = 271/656 (41%), Gaps = 38/656 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQ-HTIELQENFNALRQKNEDIC-LKIEANNNLLEQK--DNIIVELSHKLQ 2133
E S++ +EK+ E+Q + Q E++ LK E N ++ + + EL K Q
Sbjct: 9084 EESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQ 9143
Query: 2132 ENEEQRSALQNDMQSVEQMHAVSQTERE--ELNRQLVLLR---------DDVNHLKEALS 1986
E E R LQ + + +EQ+ E+E E++R+LV DV KE L
Sbjct: 9144 EEESMREILQKEKEELEQLKKDINREKEDIEISRELVESEIYEGEVKGFTDVQKYKEELQ 9203
Query: 1985 MAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALS---EKEESTKNQLLI 1815
+ ++ ++ L+ L + + + + L + K ++L+ ++ +K E +
Sbjct: 9204 IVTEELLTKKRNLEQLNSDVQHLMQTLEEVDIQYIKKKAELEHITSEIQKREQILEKQKK 9263
Query: 1814 QTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKL-----------LATKSRE 1668
+ E+N + EIE + +L+ ME ++ EK + + L + E
Sbjct: 9264 KLEENGWIIEEIEMMKVTLESINMEILQKREDMEKEKENLRREKQETELFRGELQRQRDE 9323
Query: 1667 VQGQQEGI--------LKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLP 1512
V+ ++ + LK D + A ++ + +M+ + AK++ L
Sbjct: 9324 VESSRQALIMEKDQFKLKIDHQRNEMSAAFEKEHKRLENMENDLENQRAKLAESLNDAAK 9383
Query: 1511 MKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDA 1332
M+ + +K E+ + QMV+ +++ K E+ + + +LQ + +
Sbjct: 9384 MEQKLQQMKNELNKEKEQVEEMKQMVKTERVKIEQEKEEMRKQTQEIEDGHEKLQKKTEI 9443
Query: 1331 IQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSL-KAELHLQAQ 1155
+L + ++ L+D S + + + ++ N +E++ RSL + LQ
Sbjct: 9444 ADKLLQDANSESDRLKDLSMK-------LQMQRQDIEKTNTEMETKKRSLDRMSRELQDD 9496
Query: 1154 KAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIE 975
K +++ +R+ E + L + E L ++E++DLE L+ E E+A DIE
Sbjct: 9497 K-IRLKNDRDAYEKDMTHLELKREEL---VRETEDLERKILQQRE-----QDEMAKRDIE 9547
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGN 795
+ A E +M++ +++ RNE AK E +NV R + + + +
Sbjct: 9548 NQTEALE-VMKV--DILKKRNEFAK------------EMENVHSERQKLLLLQGALQSQE 9592
Query: 794 GRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQ 615
R F +++ +C + + AEM ET + E + +EE+Q
Sbjct: 9593 SELENRVFMEEQKHLKQAKAETEECRK---------QLAEMSETVTTEQNEYRKLIEELQ 9643
Query: 614 QTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEIN 447
+ + ++ KK+ ++S ++ +L S +H + + E N
Sbjct: 9644 REKEQL-------EISKNQIEQEKKDLQNMKSNLERQL---ESLRHEKANVEDEKN 9689
Score = 76.3 bits (186), Expect = 6e-11
Identities = 85/437 (19%), Positives = 201/437 (45%), Gaps = 27/437 (6%)
Frame = -1
Query: 2279 EEKQHTIELQENFNALRQKN-EDICLKIEANNNLLEQKDNIIVELSHKL-----QENEEQ 2118
E ++H +E ++ +QK EDI I++ ++LE++ + + +LSH L +E EE
Sbjct: 14344 EAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEEL 14403
Query: 2117 RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEAL------SMAVDDRAFME 1956
L+ + +E + ++E++ + R+ R ++ LKE + ++ D+ ++
Sbjct: 14404 ERLLEKERDDIENCKKIIESEKQSIERE----RAELKRLKEEVEVQHERTLLQQDKNMIQ 14459
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIE 1776
K+ + LE +K ++E+ ++ +S+L L+++ E+ + + E
Sbjct: 14460 KEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQE---------------E 14504
Query: 1775 KLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILK---QDINIE---DE 1614
+L+G + ++E+ L K+ D+ + K ++ Q+ LK +D + DE
Sbjct: 14505 ELHGLPEEIEIEDHLKKED-----DVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDE 14559
Query: 1613 LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
+ +T E + A + + AK ++++ + +V +++ + I L ++
Sbjct: 14560 ITKTDERRQRALEETVATT---AKQPIVIKLEDTLTSEVQEMRDHLNNEIKELARMKTIM 14616
Query: 1433 QVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKEL 1254
++ +Q++ KS++ + E + + E + L++L + L + + KE+
Sbjct: 14617 KMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLDKKNKEI 14676
Query: 1253 WN---------AKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNV 1101
N A+ V+ K +N L+ + Q ++ +IQ + +V +E +
Sbjct: 14677 ENNTETFLKKIAQLETTIVLMKKDKENIENELLQLK---QIEQEREIQRKADVTSTEKEM 14733
Query: 1100 LSSEVENLKSELKESKD 1050
+ +V K+EL++SK+
Sbjct: 14734 YTEKV-TYKTELEDSKE 14749
Score = 75.5 bits (184), Expect = 1e-10
Identities = 134/627 (21%), Positives = 266/627 (42%), Gaps = 97/627 (15%)
Frame = -1
Query: 2189 NNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDV 2010
N LE + E+ ++ + E+ R +L DMQ +EQM + E+EE+ Q + ++
Sbjct: 2011 NRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEK 2070
Query: 2009 NHLKEALSMAVDDR------AFMEKQ-LQD--LENQKETVS-KELALSVSREQKLASDLK 1860
+ L+ L +D EKQ L+D +E QKE +A R+++ ++
Sbjct: 2071 DKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIR 2130
Query: 1859 ALSEKEEST--------KNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIY 1704
EK+E T + + I Q + ++ +I+ + Q E + E+I
Sbjct: 2131 VGIEKQEITFKDLKADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLVEEIE 2190
Query: 1703 DLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKV---SG 1533
K L EV +++ + + +E E ++ +E + K+ N+ A++ S
Sbjct: 2191 KRTKALDEMQMEVDKERQEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESD 2250
Query: 1532 ILEML---LPMKDDVFSLKEEVLG-----------NINSLRNDAQMVQVALEQMQDTKSE 1395
LE+ + + +F L++E LG I+ L+N +M +V +EQMQ K +
Sbjct: 2251 NLELQSENISKERTIFELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQ 2310
Query: 1394 LFAEAEI--------------RAQEVLRLQAEVDAIQ----HI-----LIELKRKNQTLQ 1284
+AE + QE+ L+ E + ++ H+ L E + K+ ++
Sbjct: 2311 QRKKAEYVKTARGRETTALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEME 2370
Query: 1283 DESQRNAKELWNAK-----------ARLNNVMSKNINLESQN-RSLKAELHLQA----QK 1152
+E+ + KE + + + M + +E++N K EL +Q +
Sbjct: 2371 NEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTE 2430
Query: 1151 AFQIQEERNVVE-SEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIE 975
+ ++ ++ VVE S+ + L + + ++L E + + +++ + + Q + +
Sbjct: 2431 TYMLETQKPVVEKSKTDELDEVRKKINADLSEVEKQKSALVQM-NLKISQEESYVKKEKD 2489
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGN 795
+ E + + +L +NE + +A E E +NV R E V I+K
Sbjct: 2490 RLKLQENEQNMQMSQLNAKQNELD--ERQAEMEKQKRELENVM-DRLEKEKVEITKE--K 2544
Query: 794 GRANQREFQNKEEDSSGVDLLKNKCTR-----------LEFQVQKLSEK----AEMFETK 660
R N+ + + K +++S VDL+K + R L +++K+ EK AE FE
Sbjct: 2545 QRVNEMQNEVKRKNAS-VDLIKQEVLREQDHIENSREILNRELEKIKEKKTILAEEFEAL 2603
Query: 659 -------SREAQQMANKLEEMQQTLSD 600
+E Q++ E+Q+ D
Sbjct: 2604 DDKKEMIGKEMQRLGKMKAELQKEAED 2630
Score = 75.5 bits (184), Expect = 1e-10
Identities = 144/718 (20%), Positives = 298/718 (41%), Gaps = 33/718 (4%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQE-N 2127
K + +L +E + +L N + + N D L I+ + LE+ I +L K ++ +
Sbjct: 13965 KTLKQLKDENESKRTQLD---NTIEKMNMDK-LSIQREKDSLEE---IKADLQRKAEKLD 14017
Query: 2126 EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL 1947
EE R A+Q Q +++ +L DD +E SM RA +E+Q
Sbjct: 14018 EEMRKAVQITSQ---------------ISQDAKILDDDREKEEELRSM----RADIERQA 14058
Query: 1946 QDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLY 1767
+ LE+ + + E + + K +DL +++ +N L +Q EL EK
Sbjct: 14059 KILESDVQLLQTE--KEILEKSKTENDLLREDLEKQRKRNDLTLQ-------ELRKEK-- 14107
Query: 1766 GSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGR 1587
+ ++QM + K+ + + L ++ K E++ ++ + +Q + D+L E+ +
Sbjct: 14108 --MALEQMITDITKE-KDAVASLQNEVSLKQHELKNKETELDEQRKEM-DDLRMQLEMRQ 14163
Query: 1586 SATDMKKVNSDA----GAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALE 1419
++T+ ++ D K+ LE + + D+ ++ + +N +
Sbjct: 14164 NSTNKQQQEVDVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAV 14223
Query: 1418 QMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKA 1239
Q D + + + + V + + E+D + +I+ K + Q+L E + +E+ +A
Sbjct: 14224 QQTDELEKFTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRA 14283
Query: 1238 RLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKE 1059
++ ++ +L + +K + + Q A + E++ VE + N+ + +N EL+
Sbjct: 14284 QIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNL--QKQKNELEELRN 14341
Query: 1058 SKDLEGYFLRLFEILLG---QHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNE 888
+ + E + + +I+L + VE I+S R EK L++L + NE + + E
Sbjct: 14342 TIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQE 14401
Query: 887 ALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLE 708
L + ER ++ + S +S+ RA + + + E LL+ ++
Sbjct: 14402 ELERLLEKERDDIENCKKIIESE--KQSIERERAELKRLKEEVEVQHERTLLQQDKNMIQ 14459
Query: 707 FQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVR-------- 552
EK + K+R +++ N EE+++ S++
Sbjct: 14460 ------KEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQEEELHGLPEEI 14513
Query: 551 ----SLKKENTRLRSEM--KGELTPSRSFKHREGS-------FIKEINIGDEDDTPLIQX 411
LKKE+ LR E+ K + S+ F+ + S + EI DE ++
Sbjct: 14514 EIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRALEE 14573
Query: 410 XXXXXXXXXXKI---DTRTSETQEIDTLMDDNRKYWNRVSHFTK-QTQSLQNSVQELQ 249
I DT TSE QE+ +++ K R+ K + L+ + ++Q
Sbjct: 14574 TVATTAKQPIVIKLEDTLTSEVQEMRDHLNNEIKELARMKTIMKMEKDQLKQAKSDIQ 14631
Score = 75.1 bits (183), Expect = 1e-10
Identities = 109/585 (18%), Positives = 249/585 (42%), Gaps = 36/585 (6%)
Frame = -1
Query: 2156 VELSHKLQENEEQ-RSALQNDMQSVE-QMHAVSQ--TEREELNRQLVLLRDDVNHLKEAL 1989
+E KL E +Q R+ + N Q ++ Q +++ TE+ +L R + ++ +++H++E +
Sbjct: 145 IEQIEKLWEGTKQERTEIDNMKQKIQRQQDEITRMTTEKGQLERTITHMKAEIDHIRERM 204
Query: 1988 SMAVD----DRAFMEKQLQDLENQKETVSKELALSVSREQKL-------ASDLKALSEKE 1842
+ +R +E+ DL+ ++ ++ ++ ++ Q L + L
Sbjct: 205 DRNKEEVNRERERVEQMRSDLQAEQSSLQQKRDEIMTERQNLEMIRYETLRQQEELESNR 264
Query: 1841 ESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQ 1662
ESTK+++ + ++++I ++ + Q L++ +I D L K +++
Sbjct: 265 ESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLMEQMKAEIEDEKNELEKKKEDIK 324
Query: 1661 GQQEGILKQDINIEDELARTK-EVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLK 1485
Q++ Q I+ +L + K E+ + + +K + A + E L ++D++ ++
Sbjct: 325 RQRD----QFEQIKLDLQQVKMEMEQRWHETEKEGLEQRAVIQREKEQLKYLQDEIQRVR 380
Query: 1484 EEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELK 1305
EEV N R ++ + Q++ E E + ++LR + +++ ++H E++
Sbjct: 381 EEVERN----REFSKQEHARISQLRAQALEENNLIENKWHDILRKEKDLEEMKH---EIE 433
Query: 1304 RKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERN 1125
R + L + KE + ++ S I++E + +K E ++Q +++
Sbjct: 434 RGREELVMNGELVKKEWEKIEQAKVDIQSHMISMEGRVDEIKRETERLKHIKTEMQRDKD 493
Query: 1124 VVESE---------------HNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVA 990
+E + + +++ E+E+ +E +LE + + + ++
Sbjct: 494 ALEKQKDDTRKAKEEAERKRYEIVTEELEHRARLQRERDELENIRAEMQRVNDVEKAKIL 553
Query: 989 SLDIESCRFAEE-KLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLI 813
ES R EE + R EL+ NA++K E ER N R E M +
Sbjct: 554 KEKEESIRIREEARQERETTELV-----NAEIKAEK-------ERLN---QRQEEM---L 595
Query: 812 SKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMAN 633
+ R + KEE + D+ + ++E ++ + E E K E Q+
Sbjct: 596 RERQEIERIKHETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKE 655
Query: 632 KLE----EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK 510
++E E+++ D+ + L+ E R++ EM+
Sbjct: 656 QMEEAKVELEEEREDLERKRDLVSREIEQAEFLRNEILRVKEEME 700
Score = 75.1 bits (183), Expect = 1e-10
Identities = 143/796 (17%), Positives = 329/796 (41%), Gaps = 40/796 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNL--LEQKDNIIVELSHKLQEN 2127
E+ R+ E ++ T +Q + ++ D+ K N + L Q+ +++ +
Sbjct: 8281 ELERIKTESQRATEHMQSH---AEERAGDLGEKEPVNTRIQRLIQEAEKASKMAWSTKHE 8337
Query: 2126 EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL 1947
E R +Q ++ SVE+ ER++++ + + ++ H +E L D+ K+
Sbjct: 8338 PEMR--MQREV-SVEE----ESVERQDMSANMQRMILEIEHARETLRGMKDEVQAARKER 8390
Query: 1946 QDLENQK-ETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQN----KQLELE 1782
+LEN K E ++ + + + EQ+ + + EK++ +++L+ E+N + +LE
Sbjct: 8391 SELENMKLEFLTMKKNMEKTYEQQ---NDEIQKEKQQIESSKMLLSRERNDLEQNRADLE 8447
Query: 1781 IEKLYGSLQMKQM--ENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELA 1608
+K +L +++ EN LL+ + + + L + E ++ Q + E
Sbjct: 8448 RQKQIMALDKQKLLAENELLEREKADVIKIIENLESLREEATRERATETAQATRRDSEEL 8507
Query: 1607 RTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQV 1428
K S D ++ + + ++ ++ L+ +K D+ + E+ L+ QM +
Sbjct: 8508 MQKMEALSMEDFQEASKNQMVELKRQIDKLIELKADLLQQQTELKKTKADLKQ--QMDDL 8565
Query: 1427 ALEQMQDTKSELFAEAEIRAQEVLRLQAEVD----AIQHILIELKRKNQTLQDESQRNAK 1260
+ + K E +++ R E++ +Q + D IQ + +E KR + L+ E K
Sbjct: 8566 EKTRSEILKHEKDTDSKTRELELIEIQRQKDDLETRIQKLTLE-KRDLEVLRSEIVLEKK 8624
Query: 1259 ELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVEN 1080
+L ++ + + S + E++ + Q+ ++ + +L N
Sbjct: 8625 DLDQKMKQVIRKRDEMEKIRSDIANATEEINRERQELEILRNNVQSARHDFELLLERTAN 8684
Query: 1079 LKSELKESKDLEGYFLRLFEIL---------LGQHVEVASLDIESCRFAEEKLMRILDEL 927
L+ E + D+E L + +I + + +E + ++I+ + ++ R + ++
Sbjct: 8685 LEDEESAATDIERLVLEVVKIREMVRNLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDI 8744
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRA---------EAMSVLISKSLGNGRANQRE 774
+R L E E +++ + RA E+M ++ K + E
Sbjct: 8745 GQIRENLGGLGEE--IEKTRRDKRELEKMRAELAEKQQEQESMREMLHKEREELEQLKDE 8802
Query: 773 FQNKEED----SSGVDLLKNKCTRLEF-QVQKLSEK----AEMFETKSREAQQMANKLEE 621
++ED V+ + +K EF +QK E+ E TK R+ Q+ + +++
Sbjct: 8803 INREKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNSDVQD 8862
Query: 620 MQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIG 441
++QT+ ++ + K+ +L + K EL +E +I E I
Sbjct: 8863 LRQTIEEINIQHGKKRAELEGIGFELKKGEQLLEKQKDEL--------KENGWIVE-EIK 8913
Query: 440 DEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSV 261
++ D+ ++ +D + ++ MD R S +Q + L+ S+
Sbjct: 8914 NKKDS--LEKINMEILRKNEDMDKEKGKLRQEKQEMDLFR------SELQRQREDLETSI 8965
Query: 260 QELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAW 81
Q+L + + I + K+L+ + Q++ ++ K F
Sbjct: 8966 QKLTHEKREME------------VLRSEIVLEKKDLDQKMKQVIRKRDEME---KIRFDI 9010
Query: 80 ANSMHDLNGQEQKLKV 33
AN+ +++G+ Q+L++
Sbjct: 9011 ANARVEIDGERQELEI 9026
Score = 75.1 bits (183), Expect = 1e-10
Identities = 126/646 (19%), Positives = 248/646 (38%), Gaps = 31/646 (4%)
Frame = -1
Query: 2279 EEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQN 2100
EEK +L + + E I K + +EQ EL ++Q E+Q +Q+
Sbjct: 9982 EEKNEMADLSRELQKAKDELEKIAYKTNKERHEVEQMQ---AELHSQIQAIEQQGQIMQD 10038
Query: 2099 DMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKET 1920
+E+ Q + EE+ + + HL L + +E D+E K+
Sbjct: 10039 KQNHLEEKELSIQRKEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQK 10098
Query: 1919 VSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQME 1740
+K+ L +L ++ L E K+ + +Q ++ ++ + +EK+ LQ
Sbjct: 10099 NNKDFELLEKIRSELENEKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQ----- 10153
Query: 1739 NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDIN-IEDELARTKEVGRSATDMKKV 1563
S+ Q ++E K D+N + E+ R K+V D K+
Sbjct: 10154 ---------------------SKREQTEKE---KADLNRVNAEIQREKQV----IDKKRH 10185
Query: 1562 NSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAE 1383
++ +E L +K ++ +E++ L + +VQ+ E + E+ +
Sbjct: 10186 MTNRA------MEELETIKTELKERQEKIQTEQEKLEEEKLLVQIEAENLNKVLEEIKRQ 10239
Query: 1382 AEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRN----------AKELWNAKARL 1233
E L+ + ++ E +RK ++++ Q N K++ K L
Sbjct: 10240 QEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQKQEL 10299
Query: 1232 N--------NVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEH---------- 1107
+++ N+E RSL E L QKA +I +R+ +E E
Sbjct: 10300 QKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNKL 10359
Query: 1106 NVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL 927
+VL +E++N ++E K +++ R K + L+E
Sbjct: 10360 DVLQNEMQNENKAMEEIK----------------------YELDGKRNEINKEQQRLEES 10397
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSS 747
+ NE K + DYE++ + E M V + + + KE D
Sbjct: 10398 LRAINEE---KGDLEIMRADYEKQE---QQIEEMRV------------EAKMERKELDQI 10439
Query: 746 GVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXX 567
+L K+K T ++++ +KL+ M E + + ++M ++L +Q + D
Sbjct: 10440 KSELEKDK-TEIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKE 10498
Query: 566 XIRVRSLKKENTRLRSEMKGELTPSRS-FK-HREGSFIKEINIGDE 435
+ ++N + + E+ R+ FK +E ++ NI DE
Sbjct: 10499 ANTEKDKIEKNKEIVERLMAEVEEQRNDFKLKKEELALERQNIVDE 10544
Score = 75.1 bits (183), Expect = 1e-10
Identities = 118/636 (18%), Positives = 280/636 (44%), Gaps = 27/636 (4%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLE-QKDNIIVELSHKLQEN 2127
KE S L + +Q +E + + ++ E + ++E + ++ QK+ + +E E
Sbjct: 10778 KERSELDNKIQQTDLE-KHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDIERQKIADEQ 10836
Query: 2126 E---EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFME 1956
+ + +S LQN+ + + ++ V + ERE L KE + ++ M+
Sbjct: 10837 DLLIQNKSELQNENERIRNINEVIKKERETL--------------KEMEAHLEKEKEEMK 10882
Query: 1955 KQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIE 1776
++ QKE + K + Q L L +++E ++ ++ + + ++
Sbjct: 10883 SITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQVS 10942
Query: 1775 K-----LYGSLQMKQMENTLLKDGNEKIYDL---CKLLATKSREVQGQQEGILKQDINIE 1620
K L +MK+ E L++ +I ++ +L K + + ++E ++ + ++
Sbjct: 10943 KQKEEDLTKQKEMKE-ERKSLEETKARIIEMKTKAELEDIKKEKEKEEEEEEMRVKVEMD 11001
Query: 1619 DELARTKEVGRSATDMKKVNSDAG---AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRN 1449
KE+ R +++K+ S+ K++ +++ K ++ +K E++ +
Sbjct: 11002 G-----KELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKSEIMKQRQQMEE 11056
Query: 1448 DAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQ- 1272
+ ++ ++Q K ++ EI + ++ ++ + IQ EL + Q + DE
Sbjct: 11057 ERSELENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDL 11116
Query: 1271 --RNAKELWNAKARLNNVMSKNINLESQNRSLK-AELHLQAQKAFQIQEERNVVESEHNV 1101
+N EL N R+ N+ N ++ + +LK E HL+ +K EE V E
Sbjct: 11117 LIQNKSELQNENERIRNL---NEIIKKERETLKEMEAHLEKKK-----EEIKSVSEETRR 11168
Query: 1100 LSSEVENLKSEL-KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL- 927
L ++E + +++ K++KD L+ Q ++ + E ++L + +DE
Sbjct: 11169 LKEDLEKMSTDVNKQNKD-----------LMNQR-DLLEQEREEINHKWKQLQQRIDEFD 11216
Query: 926 --ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEED 753
+ + E K + + E +RK++ ++A + + +K+ ++E +N+EE+
Sbjct: 11217 AQVSKQKEQDLPKEKGMKE----DRKSLEETKANVIE-MKTKAEPEEIKKEKEKENEEEE 11271
Query: 752 SSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXX 573
E +V +E+ E+++ KS E +++ ++++ Q+ L+D
Sbjct: 11272 EE----------EEEIRVIVETERKELYQIKS-ELERVRSEIDHEQKKLNDYMKMIEQEK 11320
Query: 572 XXXIRVRS-LKKENTRL---RSEMKGELTPSRSFKH 477
+++S + K+ ++ RSE+ ++ + KH
Sbjct: 11321 EDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKH 11356
Score = 74.3 bits (181), Expect = 2e-10
Identities = 113/597 (18%), Positives = 256/597 (42%), Gaps = 32/597 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNL------LEQKDNIIVELSHK 2139
E RL + +++ E QE R K+E + K E N+ E+ + + E+ +
Sbjct: 583 EKERLNQRQEEMLRERQE---IERIKHETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQ 639
Query: 2138 LQENEEQRSALQNDMQSVEQMHAVSQTEREELNR----------QLVLLRDDVNHLKEAL 1989
+++ E++ +Q + +E+ + ERE+L R Q LR+++ +KE +
Sbjct: 640 IEDIEKKVEEIQKTKEQMEEAKVELEEEREDLERKRDLVSREIEQAEFLRNEILRVKEEM 699
Query: 1988 SMA--------VDDRAFMEKQLQDLEN-QKETVSKELALSVSREQKLA--SDLKALSEKE 1842
V+ RA + +L+ LE ++ET + + S+ + + L L +
Sbjct: 700 ESRWRETETEEVELRAKTQHELERLEKLREETERSQKNIEESKIELMLWKESLDKLKGEM 759
Query: 1841 ESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQ 1662
E K+ +++Q + K E ++ + L++++ E T+ ++ ++ D + + +
Sbjct: 760 EEDKHVVIMQMNEAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQH 819
Query: 1661 GQQEGILKQDINIEDELARTKEVGRSATDM--KKVNSDAGAKVSGILEMLLPMKDDVFSL 1488
+ E + +N E E A ++ +M KK ++ + ++ L +D++
Sbjct: 820 AEMEDWFRV-VNKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKK 878
Query: 1487 KEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIEL 1308
EE + + + Q + LE+M+ + E + ++ + + V+ ++ L++
Sbjct: 879 AEE----LEQINKEIQRARQELEKMRYFEKESLQKM---LEDTQQERVFVEQVRSELLKN 931
Query: 1307 KRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEER 1128
K E KEL + ++ N + +LE + + + +++ Q+Q ++
Sbjct: 932 KADQDKCLFEMDSERKELEQMRFQVEN---EKKDLEQRRYEM---MRYDVEQSAQVQRQK 985
Query: 1127 NVVESEHNVLSSEVENL-KSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEK 951
+E + L + E++ +S +D E L + EI + E + +E + EE
Sbjct: 986 EELEKIKSQLVIDTESMNRSRELARQDREKAELLIVEIQ--EQREDVNKRLEETKQREEA 1043
Query: 950 LMRILDELICLRNENAKLKNEALYEYHDYE--RKNVSGSRAEAMSVLISKSLGNGRANQR 777
L + ++ R + K++ E L YE ++ ++ RAE + G+ ++
Sbjct: 1044 LRLLRKDMENEREDLEKIRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREK 1103
Query: 776 EFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTL 606
KEE ++ +K + +E +L+++ E + K A+ LE M+ L
Sbjct: 1104 INHEKEEMIRKMEAMKREMGEIEDMKVELTKQKENIDMKMEHARLEMTNLEMMKADL 1160
Score = 71.6 bits (174), Expect = 1e-09
Identities = 115/638 (18%), Positives = 266/638 (41%), Gaps = 70/638 (10%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDI-----------CLKIEANNNL------LE 2175
+E++ L EE K+ + E++ +R++ E I + N N+ ++
Sbjct: 7195 EEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQ 7254
Query: 2174 QKDNIIVELSHKLQEN----EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVN 2007
QK N + ++S ++ + E+++ +Q + +E+MH Q ++E + L + D+
Sbjct: 7255 QKRNALEKMSKEISRDRMKLEDEKKEIQLAREELERMHGDMQRQQEAKDHLLSGITDESL 7314
Query: 2006 HLKEALSMAVD----DRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKA------ 1857
K + + D+A ++ + ++ K+ V + + + L D ++
Sbjct: 7315 LKKSEAEIVLQPSQVDKAKPARKTEISDSDKQPVFVQQMPEMDLKDALKKDFESEKLDLP 7374
Query: 1856 -----LSEKEESTKNQLLIQTEQNK--QLELEIEKLYGSLQMKQMENTLLKDGNEKIYDL 1698
L + ++ Q LI+ E +K Q+ E++K ++ K+ + +++ +K+ D+
Sbjct: 7375 KVKDVLPQDQQMKLEQKLIEDEMDKLKQMRAELQKEADQIEKKKQD---MQNERQKLDDM 7431
Query: 1697 CKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEML 1518
L + R + E I Q +N + + + TD +++ ++ + +
Sbjct: 7432 AARLQEERRTNERLNEEINIQKVNQQKQATAFQ---MEKTDFERIKTEIDQANKELADQQ 7488
Query: 1517 LPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEV 1338
K + +++E N ++ V+ + + S A+++ +++L+ Q E+
Sbjct: 7489 EKNKKTITEMQKERETLEEMRANISKQVETITNENKSLSSRESELAKLQ-EDILQQQQEM 7547
Query: 1337 DAIQH-ILIELKRKNQT----------LQDESQRNAKELWNAKARLNNVMSKNINLESQN 1191
D +++ I++E+ + +Q + D E+ N + V+++ N++S
Sbjct: 7548 DELKNTIMMEMCQLDQRQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQTRNIKSDM 7607
Query: 1190 RSLKAELHLQAQKAFQIQEERNVVESEHNVLSS--------------EVENLKSELK--- 1062
SLK E Q ++ EE++++E E +L+ E+ENLK E +
Sbjct: 7608 VSLKMEKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIK 7667
Query: 1061 -ESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL-ICLRNENAKLKNE 888
E K+LE + L +G E + + EE + +L I R K E
Sbjct: 7668 NEKKELEKMKISLQRKAIG-FKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEE 7726
Query: 887 ALYEYHDYERKN-VSGSRAEAMSVLISKSLGNGRANQRE-FQNKEEDSSGVDLLKNKCTR 714
L + RK + + + K+ ++ E ++ + E + + LK T
Sbjct: 7727 RLDQTEKKRRKTYYTEDLFQEEKTDLQKTKEEINYDREEIYRQRTELNKEKETLKQMHTS 7786
Query: 713 LEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSD 600
+++ + ++ E + E Q+ +L+ Q+ + D
Sbjct: 7787 NLKEIENIEKEKEKIQRTWNELDQIRAELQNKQRDMDD 7824
Score = 70.9 bits (172), Expect = 2e-09
Identities = 128/646 (19%), Positives = 260/646 (40%), Gaps = 99/646 (15%)
Frame = -1
Query: 2258 ELQENFNALRQ-----KNEDICLKIEANNNLLEQKD--NIIVELSHKLQENEEQRSALQN 2100
ELQ +R KNE LK + ++K+ +II E S + ++ E+ + +
Sbjct: 10554 ELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNV 10613
Query: 2099 DMQSVEQMHAVSQTEREELNRQLVLLRDDVNH-------------------------LKE 1995
Q ++ + EREE+N + + ++ L+E
Sbjct: 10614 QKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEE 10673
Query: 1994 ALSMAVDDRAFME-------KQLQDLENQKETVSKE--------LALSVSRE-------- 1884
++ + E +++++L+ +E + KE + L + RE
Sbjct: 10674 VNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSE 10733
Query: 1883 ------------QKLASDLKAL-SEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQM 1743
+KL D+K + EKE+ K + I T Q +++E E +L +Q +
Sbjct: 10734 LVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMT-QKQEMEKERSELDNKIQQTDL 10792
Query: 1742 ENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDE----LARTKEVGRSATD 1575
E ++ E + L + + E+Q Q+E + + I DE + E+
Sbjct: 10793 EKHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDIERQKIADEQDLLIQNKSELQNENER 10852
Query: 1574 MKKVNSDAGAKVSGILEM---LLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDT 1404
++ +N + + EM L K+++ S+ EE L + ++ + +
Sbjct: 10853 IRNINEVIKKERETLKEMEAHLEKEKEEMKSITEETRRQKEDLEKMSTDIKEQNQDLMKQ 10912
Query: 1403 KSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNV 1224
+ L E E E +LQ +D + + K ++ T Q E + K L KAR+ +
Sbjct: 10913 RDLLEQEKEDINHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEM 10972
Query: 1223 MSK----NINLESQNRSLKAELHLQAQK--------AFQIQEERNVVESEHNVLSSE--- 1089
+K +I E + + E+ ++ + +++ ER+ ++ E L+ +
Sbjct: 10973 KTKAELEDIKKEKEKEEEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKI 11032
Query: 1088 -------VENLKSE-LKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILD 933
+E +KSE +K+ + +E L + ++E DIE+ + +KLM ++
Sbjct: 11033 IEQEKQNLEKMKSEIMKQRQQMEEERSELENKIKQTYIE--KCDIENSKEIVQKLMVEVE 11090
Query: 932 ELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEED 753
E + + + E L D ER+ + A+ +LI N+ E QN+ E
Sbjct: 11091 E----QKHEIQFQKEEL----DIERQKI----ADEQDLLIQ--------NKSELQNENER 11130
Query: 752 SSGV-DLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEM 618
+ +++K + L+ L +K E ++ S E +++ LE+M
Sbjct: 11131 IRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRLKEDLEKM 11176
Score = 70.1 bits (170), Expect = 4e-09
Identities = 121/594 (20%), Positives = 247/594 (41%), Gaps = 45/594 (7%)
Frame = -1
Query: 2258 ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQ 2079
+++EN L ++ IE + + + EL+ K QE E R L + + +EQ
Sbjct: 8746 QIRENLGGLGEE-------IEKTRRDKRELEKMRAELAEKQQEQESMREMLHKEREELEQ 8798
Query: 2078 MHAVSQTERE--ELNRQLV----------------LLRDDVNHLKEALSMAVDDRAFMEK 1953
+ E+E E+ R+LV ++++ + E L D +
Sbjct: 8799 LKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNS 8858
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEK 1773
+QDL E ++ + + + + +LK + E K++L ++N + EI+
Sbjct: 8859 DVQDLRQTIEEINIQHGKKRAELEGIGFELKKGEQLLEKQKDEL----KENGWIVEEIKN 8914
Query: 1772 LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSR------EVQGQQEGILKQDINIEDEL 1611
SL+ ME +L+ + + KL K E+Q Q+E L+ I
Sbjct: 8915 KKDSLEKINME--ILRKNEDMDKEKGKLRQEKQEMDLFRSELQRQRED-LETSIQKLTHE 8971
Query: 1610 ARTKEVGRSATDMKKVNSDAGAK-VSGILEMLLPMKDDVFSLKEEVLG---NINSLRNDA 1443
R EV RS ++K + D K V + + ++ D+ + + E+ G + LR++
Sbjct: 8972 KREMEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRFDIANARVEIDGERQELEILRDNV 9031
Query: 1442 QMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNA 1263
Q + E++ + + L E E A ++ RL EV I+ ++ LK + + +ES+
Sbjct: 9032 QSARQDFERLVERTANLEVE-ESAATDIERLVLEVVKIREMVRNLKGEMERRMEESKVEI 9090
Query: 1262 KELWNAKARLNNVMSKNINLESQNRSLKAEL--------HLQAQKAFQIQEERNVVESEH 1107
E K+ + ++ + LK E+ +L+ KA +++E++ ES
Sbjct: 9091 DEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKA-ELEEKQQEEESMR 9149
Query: 1106 NVL---SSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRIL 936
+L E+E LK ++ K+ L E + + D++ + E+L +
Sbjct: 9150 EILQKEKEELEQLKKDINREKEDIEISRELVESEIYEGEVKGFTDVQKYK---EELQIVT 9206
Query: 935 DELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEE 756
+EL+ + +L ++ + E ++ + +A I+ + R E Q K+
Sbjct: 9207 EELLTKKRNLEQLNSDVQHLMQTLEEVDIQYIKKKAELEHITSEI-QKREQILEKQKKKL 9265
Query: 755 DSSG-----VDLLKNKCTRLEFQV-QKLSEKAEMFETKSREAQQMANKLEEMQQ 612
+ +G ++++K + ++ QK + + E RE Q+ E+Q+
Sbjct: 9266 EENGWIIEEIEMMKVTLESINMEILQKREDMEKEKENLRREKQETELFRGELQR 9319
Score = 69.3 bits (168), Expect = 7e-09
Identities = 125/585 (21%), Positives = 244/585 (41%), Gaps = 25/585 (4%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEE 2121
EVS E K EL E R++ +D+ +++E N ++ E+ + EN +
Sbjct: 14130 EVSLKQHELKNKETELDEQ----RKEMDDLRMQLEMRQNSTNKQQQ---EVDVFIVENMK 14182
Query: 2120 QRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQD 1941
R ND++S M + ER +L + D N L + + AV +EK D
Sbjct: 14183 MR----NDLES---MKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTD 14235
Query: 1940 LENQKETVSKEL-ALSVSREQ--KLASDLKALSEKEESTKNQLLIQTEQNKQLE-LEIEK 1773
++ +KE V KE + V ++ K +L++L+ + E K ++ + Q + LE L +
Sbjct: 14236 IKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADL 14295
Query: 1772 LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEV 1593
L G+ +K + T + E K EV+ Q L++ N +EL T E
Sbjct: 14296 LAGADDIKTLVQTEKQMAIED--------TEKKTEVELQMN--LQKQKNELEELRNTIEA 14345
Query: 1592 GRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRND-AQMVQVALEQ 1416
+ + +K+ D K + ++ + DV ++ L ++ + N+ Q Q LE+
Sbjct: 14346 EKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELER 14405
Query: 1415 MQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKAR 1236
+ L+ E D I++ ++ + Q++ +R EL K
Sbjct: 14406 L--------------------LEKERDDIENCKKIIESEKQSI----ERERAELKRLKEE 14441
Query: 1235 LNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVE------SEHNVLSSEVENLK 1074
+ + + + +N K + HL+ +KA +E N+ E SE ++L+ E+E +
Sbjct: 14442 VEVQHERTLLQQDKNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKR 14501
Query: 1073 SE-----LKESKDLEGYFLRLFEILLGQHVEVASLDIE-------SCRFAEEKLMRILDE 930
E L E ++E + + ++L + ++ D + R AE + LDE
Sbjct: 14502 QEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTS--LDE 14559
Query: 929 LICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKE--E 756
+ + + + AL E V+ + + + + + +L + R+ N E E
Sbjct: 14560 I----TKTDERRQRALEE-------TVATTAKQPIVIKLEDTLTSEVQEMRDHLNNEIKE 14608
Query: 755 DSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEE 621
+ ++K + +L+ + + E FE EA + ++ EE
Sbjct: 14609 LARMKTIMKMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNEE 14653
Score = 69.3 bits (168), Expect = 7e-09
Identities = 86/415 (20%), Positives = 173/415 (41%), Gaps = 36/415 (8%)
Frame = -1
Query: 2180 LEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHL 2001
++Q H +++EE+ SA + +V ++ +E +E+ L +DV +
Sbjct: 15237 IQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVARM 15296
Query: 2000 KEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQL 1821
K + M D +E+ D++ Q E + + ++ + + L L+ +E N L
Sbjct: 15297 KTIMKMEKDQ---LEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTL 15353
Query: 1820 LIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKI-YDLCKLLAT-KSREVQ----- 1662
++NK++E E + + L+K E I +L +L T + RE+Q
Sbjct: 15354 ---DKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQEREIQRGTDD 15410
Query: 1661 -GQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDA-GAKVSGILEM---------LL 1515
+ + + + EL KE + D +DA AK G E +L
Sbjct: 15411 TSNEREKYDEKVTYKTELEDNKEKKKPDRDSSLKLTDADSAKTDGEREAQTLETKVQDVL 15470
Query: 1514 PMKDDVFSLKEE----------VLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQ 1365
+ DD +EE ++ +N + D Q ++ ++ KS + E R
Sbjct: 15471 QLTDDTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEKCRSAEEEKSVIMESLERRRN 15530
Query: 1364 EVLRLQAEV----DAIQHILIELKRKNQTLQDESQRNAKEL---WNAKARLNNVMSKNIN 1206
+ ++Q+EV I+H L ++K + Q ++ + QR + + W ++ +
Sbjct: 15531 SLEKVQSEVLTLTQEIEH-LAQIKTEMQQIETKMQRQTRSVATQWETDVQIQQEGQEATE 15589
Query: 1205 LESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-KESKDLE 1044
+ + K+E + A+K ++ V + L+SEV+ ++ L KE +D+E
Sbjct: 15590 TRG-HITKKSEEEISAKKT-----KQPTVTKLEDTLTSEVQEMRDSLNKEMEDVE 15638
Score = 68.9 bits (167), Expect = 9e-09
Identities = 119/605 (19%), Positives = 261/605 (43%), Gaps = 46/605 (7%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQ 2103
E E + +E Q++ + + E+ ++ + + + N +L +LQ +EQ +
Sbjct: 9594 ELENRVFMEEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQREKEQLEISK 9653
Query: 2102 NDMQSVEQMHAVSQTEREELNRQLVLLR-------DDVNHLKEALSMAVDDRAFMEKQLQ 1944
N +EQ Q + L RQL LR D+ N L++ S + + + + K+ +
Sbjct: 9654 NQ---IEQEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKERE 9710
Query: 1943 DLEN-------QKETVSKEL-ALSVSREQ--KLASDLKALSEKEESTKNQLLIQTEQNKQ 1794
DLEN +K+ + +E L + RE+ K+ S+L+ E ES + ++ + E+ Q
Sbjct: 9711 DLENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINNKMEELLQ 9770
Query: 1793 LEL-------EIEKLYGSLQ--MKQMENTL--LKDGNEKIYDLCKL-LATKSREVQGQQE 1650
+++ EIEK LQ +EN ++ +K D+ + + K RE++ Q +
Sbjct: 9771 MKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQLD 9830
Query: 1649 GILKQDINIEDEL-ARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVL 1473
K+ + +E+ + K++ DMK+ + G+LE K ++ K+E+
Sbjct: 9831 ---KETKRLSEEIELKVKDLEMEMADMKRQKQEI-EDTKGLLE---KEKQELKQEKKELE 9883
Query: 1472 GNINSLRNDAQMVQVALEQMQDTKS---ELFAEAEIRAQEVLRLQAEVDAIQHILIELKR 1302
+ L + Q + + K+ +L E EI +++ ++ ++ +Q + + +R
Sbjct: 9884 DQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQR 9943
Query: 1301 KNQTLQDESQRNAKELWNAKARLNN-----VMSKNINLESQNRSLKAELHLQAQK----- 1152
N ++E+++ + L + +S +E +N LQ K
Sbjct: 9944 LNDQTREENKKEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDELEK 10003
Query: 1151 -AFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIE 975
A++ +ER+ VE L S+++ ++ + + +D + + L E+ + + E +
Sbjct: 10004 IAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQDKQNH-LEEKELSIQRKEEEIKIGNT 10062
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGN 795
+ +E L +L+ E K +++ D E ++ + I L N
Sbjct: 10063 EFQIEQEHLNNVLE-------ETNKRQHDLEVMRADIELNKQKNNKDFELLEKIRSELEN 10115
Query: 794 GRANQREFQNKEEDSSGVDL--LKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEE 621
+ + + + +++ V L L+ + RLE +L K E E + + ++ +++
Sbjct: 10116 EKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQTEKEKADLNRVNAEIQR 10175
Query: 620 MQQTL 606
+Q +
Sbjct: 10176 EKQVI 10180
Score = 68.6 bits (166), Expect = 1e-08
Identities = 116/606 (19%), Positives = 255/606 (42%), Gaps = 39/606 (6%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQK-NEDICLK----------IEANNNLLEQKDNII 2157
+ + +L +E ++ ++ E N RQ+ E+I LK I+ L II
Sbjct: 7855 ENIQKLMKELQEERLKTSEALNKERQQFTEEIKLKNDSLDEIQAEIDRQKRALVTDKEII 7914
Query: 2156 VELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAV 1977
+ LQ+ ++ R Q+D + + + Q ERE L++ V + L+ +
Sbjct: 7915 TKQMMDLQKTQDVRR--QSDESDIARANL--QRERESLDQLSVEILKQKQDLERERDELL 7970
Query: 1976 DDRAFMEKQLQDLENQKETVSKELALSVSREQ---KLASDLKALSEKE---ESTKNQLLI 1815
+ +E Q D EN K+ ++ L S E+ +L D + E + +L +
Sbjct: 7971 EQWRLVETQKMDNENVKQLKTELLDEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNL 8030
Query: 1814 QTEQNKQLELEIEKLYGSLQMK------QMENTLLK-----DGNEKIYDLCKLLATKSRE 1668
Q + + ++E++ G LQMK +M+ L + + + Y + L + E
Sbjct: 8031 QKQGIQDERAQLERMKGELQMKADDIERKMQEILYEKQKYAERKSENYKIQTYLDEANAE 8090
Query: 1667 VQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKV---SGILEMLLPMKDDV 1497
VQ + + + D N+E E+ ++ + ++V GAK+ I + L +D +
Sbjct: 8091 VQKLNKELERYDENLE---KCKLELDKARAETERVKQ--GAKIPETQQIEQSLQKERDYI 8145
Query: 1496 FSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHIL 1317
++ + ++ D +++ +++ ++++ + E ++ + + E IQ
Sbjct: 8146 EDIRRNLFKKEEAIEKDKAEIRLRHQELDLIQAKVVKQKEEMVKQKIESERE---IQQEK 8202
Query: 1316 IELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQ 1137
+L+R + L+D+ Q+ +E+ K + K +++++ R + A+K +++
Sbjct: 8203 KKLQRSEEELEDKMQKIKREMIELKLLQDETDGKRKDVDNKMRQV-------ARKRDELE 8255
Query: 1136 EERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAE 957
+ + VES L + L +E E + ++ R E + H E + D+
Sbjct: 8256 KMKADVESASKKLEVDRVMLNTERDELERIKTESQRATE-HMQSHAEERAGDLGEKEPVN 8314
Query: 956 EKLMRILDEL--------ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSL 801
++ R++ E +++ E E ER+++S + + M + I +
Sbjct: 8315 TRIQRLIQEAEKASKMAWSTKHEPEMRMQREVSVEEESVERQDMS-ANMQRMILEIEHAR 8373
Query: 800 GNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEE 621
R + E Q ++ S ++ +K LEF K + +E ++ E Q+ ++E
Sbjct: 8374 ETLRGMKDEVQAARKERSELENMK-----LEFLTMK-KNMEKTYEQQNDEIQKEKQQIES 8427
Query: 620 MQQTLS 603
+ LS
Sbjct: 8428 SKMLLS 8433
Score = 65.5 bits (158), Expect = 1e-07
Identities = 110/608 (18%), Positives = 255/608 (41%), Gaps = 40/608 (6%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIE--LQENFNALRQKNEDICLKIEANNNLLEQKDNI-----IVELSH 2142
E+ +L + E++ I+ + N +E + K E ++ ++K + + +
Sbjct: 15048 ELLQLKQTEQEREIQRGTDDTSNERENYDEKVTYKTELEDSKEKKKPDRDSSLKLTDADS 15107
Query: 2141 KLQENEEQRSALQNDMQSVEQMHAVSQTEREEL-----NRQLVLL-----RDDVNHLKEA 1992
+ E + L+ +Q V Q+ + ++EEL N+ ++L + D+ LKE
Sbjct: 15108 AKTDGEREAQTLETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEE 15167
Query: 1991 LSMAVDDRAFMEKQLQDLENQKETVSKELALSVSRE----QKLASDLKALSEKEESTKNQ 1824
A ++++ + + L+ N E V E+ LS+++E ++ ++++ + K +
Sbjct: 15168 CRSAEEEKSVIMESLERRRNSLEKVQSEV-LSLTQEIDHLAQIKTEMQQIEIKMQIQTRS 15226
Query: 1823 LLIQTEQNKQLEL--EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQE 1650
+ Q E + Q++ E + G + K E K + + KL T + EVQ ++
Sbjct: 15227 VATQWETDVQIQQGQEATETTGHITKKSEEEISAKKTKQPT--VTKLEDTLTSEVQEMRD 15284
Query: 1649 GILKQDINIEDELARTKEVGRSATD-MKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVL 1473
+ K+ +++AR K + + D +++ SD ++ + ++ +E++L
Sbjct: 15285 SLNKE----MEDVARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLL 15340
Query: 1472 G---NINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKR 1302
+ L N +E +T + A+ E ++ ++ + + I++ L++LK+
Sbjct: 15341 QLTHDKEDLSNTLDKKNKEIENNTETSLKKIAQLETT---IVLMKKDKENIENELLQLKQ 15397
Query: 1301 KNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNV 1122
Q + E QR + N + + + ++ LE K + + K +
Sbjct: 15398 TEQ--EREIQRGTDDTSNEREKYDEKVTYKTELEDNKEKKKPDRD-SSLKLTDADSAKTD 15454
Query: 1121 VESEHNVLSSEVENL----KSELKESKDLEGYFLRLFEILLGQHVEVASLDI----ESCR 966
E E L ++V+++ ++ ++L +I+L + A D+ E CR
Sbjct: 15455 GEREAQTLETKVQDVLQLTDDTTQDQEELHDEMENKMKIIL--ELNEAKKDLQKLKEKCR 15512
Query: 965 FAEEKLMRILDELICLRNENAKLKNEAL---YEYHDYERKNVSGSRAEAMSVLISKSLGN 795
AEE+ I++ L RN K+++E L E + + E ++S+
Sbjct: 15513 SAEEEKSVIMESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIETKMQRQTRSVAT 15572
Query: 794 GRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEK--AEMFETKSREAQQMANKLEE 621
+ Q + ++++ K + E +K + ++ +T + E Q+M + L +
Sbjct: 15573 QWETDVQIQQEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNK 15632
Query: 620 MQQTLSDM 597
+ + M
Sbjct: 15633 EMEDVERM 15640
Score = 63.2 bits (152), Expect = 5e-07
Identities = 127/614 (20%), Positives = 263/614 (42%), Gaps = 70/614 (11%)
Frame = -1
Query: 2231 RQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTER 2052
R + ++ I+ LE II++ H+L + +E A++ND + E+M + + E+
Sbjct: 1518 RASDLELSASIQKERQELEHYKEIILKEKHELNKIKEDVKAVKNDAE--ERMIKLHEEEK 1575
Query: 2051 EELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLA 1872
E +++ L E+QLQ +KE K L + Q+L
Sbjct: 1576 EMKTKRVSLQN-------------------WERQLQ---TEKEKNQKGLDAIWNENQQLN 1613
Query: 1871 SDLKALSEKEESTKNQLLIQTEQNK---QLELEIEKLYGSLQMKQMENTLLKDGNEKIYD 1701
+ L KE L +Q+E++K + LEI+++ +Q + ME+ D I +
Sbjct: 1614 ERKQQLDIKE------LHLQSEKSKLEYKKPLEIKQVDAQVQTELMEDASEYDMALSIEE 1667
Query: 1700 LCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEM 1521
L K + + ++ ++ +L Q +E ++A E+ R +++ + + +E+
Sbjct: 1668 LDK----QRQFLEYFKQELLAQKCTMERQMAEI-ELSRDELSLREATLQTATQTTADMEL 1722
Query: 1520 LLPM--------KDDVFSLKEEV-------LGNINSLRNDAQMVQVALEQMQDTKSELFA 1386
L + KD++ K EV I R +MV++ LE+ +D + +
Sbjct: 1723 QLELQKQELEQTKDEMERTKLEVQKGWVDLQTQIAESREKEEMVRIELEKARDVLNRIRQ 1782
Query: 1385 EAEIRAQEV-----LRLQAE---VDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLN 1230
+ E Q + L E ++A + ++ + KR + ++ E QR + + +K +
Sbjct: 1783 DVETEKQTMEADLKFTLAKEFENLEAQRKMMEDEKRALENMKYELQRESGYIERSK---H 1839
Query: 1229 NVMSKNINLESQNRSLK---AELHLQAQKAFQIQEER------------------NVVES 1113
N+ + N+E+ LK EL + Q+Q ER N +++
Sbjct: 1840 NMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERSREIKDLENLRELNELTLNQIKT 1899
Query: 1112 EHNVL----------SSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRF 963
+ +VL E+EN KS++K + Y L+ + L + + DI++ F
Sbjct: 1900 KSDVLEKISELNSQQKDEIENEKSKIK----IREYDLQQMQTDLNRQ-QKEMQDIQNAVF 1954
Query: 962 AEE-KLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRA----------EAMSVL 816
E+ +L + DE+ E K + + ++ E+ N+ RA M+ L
Sbjct: 1955 MEKSELKKSQDEIA----EQLKQVGD-MMQFTQNEKDNLDRERAAIIEQKLQMERDMTHL 2009
Query: 815 ISKSLGNGRANQREFQNKEE--DSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQ 642
+++ L + + ++E N++ + + L+++ + ++ EK EM + + + +
Sbjct: 2010 LNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEM-QLQRQSIAE 2068
Query: 641 MANKLEEMQQTLSD 600
+KLE + QTL++
Sbjct: 2069 EKDKLESVLQTLAE 2082
Score = 63.2 bits (152), Expect = 5e-07
Identities = 119/611 (19%), Positives = 253/611 (41%), Gaps = 43/611 (7%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQ---- 2133
E+ +L + E++ E+Q + + E K+ L + K+ I + L+
Sbjct: 14707 ELLQLKQIEQER--EIQRKADVTSTEKEMYTEKVTYKTELEDSKEKIKPDRDSTLELTDT 14764
Query: 2132 -----ENEEQRSALQNDMQSVEQMHAVSQTEREEL-----NRQLVLL-----RDDVNHLK 1998
+ E + L+ +Q V Q+ + ++EEL N+ ++L + D+ LK
Sbjct: 14765 DSAKTDGEREAQTLETKVQDVLQLTDDTTQDQEELHDEMENKMKIILELNKAKKDLQKLK 14824
Query: 1997 EALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSRE----QKLASDLKALSEKEESTK 1830
E A ++++ + + L+ N E V E+ LS+++E ++ ++++ + K +
Sbjct: 14825 EECRSAEEEKSVIMESLERRRNSLEKVQSEV-LSLTQEIDHLAQIKTEMQQIEIKMQIQT 14883
Query: 1829 NQLLIQTEQNKQLELEIEK---LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQG 1659
+ Q E + Q++ E ++ G + K E K + I + KL T + EVQ
Sbjct: 14884 RSVATQWETDVQIQQEGQEPIETTGHITKKSEEEISAKKTKQPI--VTKLEDTLTSEVQE 14941
Query: 1658 QQEGILKQDINIEDELARTKEVGRSATD-MKKVNSDAGAKVSGI---LEMLLPMKDDVFS 1491
+ D+ IED +AR K + + D +++ SD ++ +E L K
Sbjct: 14942 MR------DMEIED-VARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEETLKEKSRNEE 14994
Query: 1490 LKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIE 1311
++L + + L N +E + T A+ E + ++ + + I++ L++
Sbjct: 14995 TLLQLLHDKDDLSNTLDEKSKEIENITVTFKRNIAQLETT---IAMMKKDKENIENELLQ 15051
Query: 1310 LKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEE 1131
LK+ Q + E QR + N + + ++ LE K + + K
Sbjct: 15052 LKQTEQ--EREIQRGTDDTSNERENYDEKVTYKTELEDSKEKKKPDRD-SSLKLTDADSA 15108
Query: 1130 RNVVESEHNVLSSEVENLKS----ELKESKDLEGYFLRLFEILLGQHVEVASLDI----E 975
+ E E L ++V+++ ++ ++L +I+L + A D+ E
Sbjct: 15109 KTDGEREAQTLETKVQDVLQLTDYTTQDQEELHDEMENKMKIIL--ELNEAKKDLQKLKE 15166
Query: 974 SCRFAEEKLMRILDELICLRNENAKLKNEAL---YEYHDYERKNVSGSRAEAMSVLISKS 804
CR AEE+ I++ L RN K+++E L E + + E + ++S
Sbjct: 15167 ECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRS 15226
Query: 803 LGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEK--AEMFETKSREAQQMANK 630
+ + Q +E + + K + E +K + ++ +T + E Q+M +
Sbjct: 15227 VATQWETDVQIQQGQEATETTGHITKK-SEEEISAKKTKQPTVTKLEDTLTSEVQEMRDS 15285
Query: 629 LEEMQQTLSDM 597
L + + ++ M
Sbjct: 15286 LNKEMEDVARM 15296
Score = 62.0 bits (149), Expect = 1e-06
Identities = 117/589 (19%), Positives = 235/589 (39%), Gaps = 54/589 (9%)
Frame = -1
Query: 2108 LQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQ 1929
L++ + + V TER EL + L+ + +++ ++ +EK DLE Q
Sbjct: 13065 LESGKDETDGLTEVHTTERRELEITKLALQSEQQEIEKIRQDIDREKNDLEKYRSDLEKQ 13124
Query: 1928 -------KETVSKELALSVSREQKLASDLKALSEKEESTKNQL--------LIQTEQNK- 1797
K+ + E A + + + K+ E+ ES + QL I E NK
Sbjct: 13125 YEEMEICKQNIENERAELEIDLENIIIETKSKQERLESIEVQLQEKNVQMGTILDELNKR 13184
Query: 1796 QLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCK---LLATKSREVQGQQEGILK---Q 1635
Q EL+ K + +QM +T + +E I L K ++ E+Q Q+E + K Q
Sbjct: 13185 QEELDAIKAKTQREKEQMGHTEELEKDELIAILQKREEIVKRHMEEIQNQREELQKEKDQ 13244
Query: 1634 DINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSL---------KE 1482
N++ EL + G+ +M ++ ++ + + L + + F L E
Sbjct: 13245 FGNMQAELQK----GQLEMEMHQLMLNSERDELNGMRVNLEKQKEEFELMQQNLESRRPE 13300
Query: 1481 EVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQ---HILIE 1311
+L +I + + + L + Q+ + +E R +++ +++ E+ Q L E
Sbjct: 13301 SLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKIKQIEGEIKTKQIEMACLEE 13360
Query: 1310 LKRKNQTLQ--------DESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQ 1155
LK+K Q E Q +EL K ++ + L Q K EL
Sbjct: 13361 LKQKELDEQKNMRECENQELQMRREELAKMKTEIDIERDEIQKLRKQYEKEKCELEQIKP 13420
Query: 1154 KAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIE 975
+ + E+ E +H+ + +++LK E +E +E D++
Sbjct: 13421 DLQKREPEKIDAEVQHDEIHGGIDSLKEEREE-------------------IEKMKADLQ 13461
Query: 974 SCRFAEEKLMRILD-ELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVL-ISKSL 801
+ E + I+ E L + A+++ A+ + KN+ + ++L ++K
Sbjct: 13462 NKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIEAILKVTKKQ 13521
Query: 800 GN--GRANQREFQNKEEDSSGVDLLKNKCTRL--------EFQVQKLSEKAEMFETKSRE 651
N + N+ + K E + +L+ + T L EF + K+ E+ +T R
Sbjct: 13522 KNYLEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKMEEREAERKTIERV 13581
Query: 650 AQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGE 504
+MA + E++++ ++ + E T+ +SE++ E
Sbjct: 13582 MDEMAEEHEKIKKEREELVNMEEEIKKQRRVLEESMNEMTKKKSELQHE 13630
Score = 60.5 bits (145), Expect = 3e-06
Identities = 107/584 (18%), Positives = 246/584 (42%), Gaps = 26/584 (4%)
Frame = -1
Query: 2291 RLYEEEKQHTIELQENFNALRQKNEDI-CLKIE---ANNNLLEQKDN---IIVELSHKLQ 2133
RL EE + Q+ A + + D +K E AN L +Q++ I E+ + +
Sbjct: 7444 RLNEEINIQKVNQQKQATAFQMEKTDFERIKTEIDQANKELADQQEKNKKTITEMQKERE 7503
Query: 2132 ENEEQRSALQNDMQSV-EQMHAVSQTERE--ELNRQLVLLRDDVNHLKEALSMAV----- 1977
EE R+ + ++++ + ++S E E +L ++ + +++ LK + M +
Sbjct: 7504 TLEEMRANISKQVETITNENKSLSSRESELAKLQEDILQQQQEMDELKNTIMMEMCQLDQ 7563
Query: 1976 --DDRAFMEKQLQDLENQKET----VSKELALSVSREQKLASDLKALSEKEESTKNQLLI 1815
D ++K++ DL + +T V +E +++ + + SD+ +L ++E+ + L
Sbjct: 7564 RQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLK 7623
Query: 1814 QTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQ 1635
E+ +E E E L +L + +K E L + ++ +++ + K
Sbjct: 7624 LNEEKDLIEKERELLTKNLDHTDKDKMDMKRELEN-------LKVEKETIKNEKKELEKM 7676
Query: 1634 DINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSL 1455
I+++ + KE D + + + A+ + L++ + F EE L
Sbjct: 7677 KISLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFI--EERLDQTEKK 7734
Query: 1454 RNDAQMVQVALEQ----MQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTL 1287
R + ++ +Q TK E+ + E E+ R + E++ + L ++ N
Sbjct: 7735 RRKTYYTEDLFQEEKTDLQKTKEEINYDRE----EIYRQRTELNKEKETLKQMHTSNLKE 7790
Query: 1286 QDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEH 1107
+ ++ +++ L+ + ++ L+++ R + ++ ++ ++ + +++E
Sbjct: 7791 IENIEKEKEKIQRTWNELDQIRAE---LQNKQRDMDDTTNIMMKEKAELARDLENLQNEK 7847
Query: 1106 NVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL 927
+ L EN++ +KE L+ L+ E L + + E + + L I E+
Sbjct: 7848 DELQKSRENIQKLMKE---LQEERLKTSEALNKERQQFT----EEIKLKNDSLDEIQAEI 7900
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRAN-QREFQNKEEDS 750
R + A + ++ + + + R + S RAN QRE + D
Sbjct: 7901 D--RQKRALVTDKEIITKQMMDLQKTQDVRRQ------SDESDIARANLQRE--RESLDQ 7950
Query: 749 SGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEM 618
V++LK K LE + +L E+ + ET+ + + + E+
Sbjct: 7951 LSVEILKQK-QDLERERDELLEQWRLVETQKMDNENVKQLKTEL 7993
Score = 59.7 bits (143), Expect = 5e-06
Identities = 119/587 (20%), Positives = 244/587 (41%), Gaps = 18/587 (3%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
KE + EE + EL+E Q+N+++ E +LLE++ + +LQ+
Sbjct: 12634 KEYESIIEETNRKRTELEEIEVDQSQQNKNV----ETMKDLLEKERKDTEKEREELQKQA 12689
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQ----LVLLRDDVNHLKEALSMAVDDRAFME 1956
+ + E+M S E ++L Q ++ RDD+ KE + ++ ++
Sbjct: 12690 DDLEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQ 12749
Query: 1955 KQLQDLENQKETVSKELA---LSVSREQK-LASDLKALSEKEESTKNQLLIQTEQNK-QL 1791
K++Q+ +N+ E + EL + + +EQK L L ++E+ + + +++ + K Q
Sbjct: 12750 KEIQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLE---IVRVDYEKHQQ 12806
Query: 1790 ELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDEL 1611
++E ++ ++ +++ + K L+ K E G+LK+++
Sbjct: 12807 QIEEMRVKTKMERDELDQLMAK----------MLMDRKENERSKDMIGLLKKEM------ 12850
Query: 1610 ARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQ 1431
+ K N DA E L K + + K+++ ++ +A V+
Sbjct: 12851 -----------EQTKFNLDAQE------EELKLEKQKIQNEKKDLEMFKAEIKREASEVK 12893
Query: 1430 VALEQM--QDTKS-ELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAK 1260
EQ +DTK+ E E + Q V + E + IQ + E+KR + E + K
Sbjct: 12894 TLKEQQLEKDTKAFEALKEEHLPGQFVQQKGGEFERIQ--IDEVKR----ILSEIHKEKK 12947
Query: 1259 ELWNAKARLNNVMSKNINLESQNRSLKAELHL--QAQKAFQIQEERNVVESEHNVLSSEV 1086
EL K L + + ++S+ S + ++ L A + +++ +V S+ +
Sbjct: 12948 ELERNKQILEHQREALLEIKSKQPSERLDVILVSSATQTSDLEDIPDVSASQGETVEKHT 13007
Query: 1085 ENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMR----ILDELICL 918
+ +K E S E Y + + L Q + E + A+ ++ I D I +
Sbjct: 13008 DIIK-EYTTSIPKEEYEI---DKLKQQGDKKLKSTREDTKMADTEVTTQYKYIPDPSIMM 13063
Query: 917 RNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVD 738
+ E+ K + + L E H ER+ + ++ A Q E Q E+ +D
Sbjct: 13064 KLESGKDETDGLTEVHTTERRELEITKL---------------ALQSEQQEIEKIRQDID 13108
Query: 737 LLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDM 597
KN + ++K E+ E+ + Q + N+ E++ L ++
Sbjct: 13109 REKNDLEKYRSDLEKQYEEMEICK------QNIENERAELEIDLENI 13149
>ref|XP_003701630.1| PREDICTED: major antigen-like [Megachile rotundata]
Length = 2226
Score = 126 bits (316), Expect = 5e-26
Identities = 157/765 (20%), Positives = 325/765 (42%), Gaps = 38/765 (4%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQ 2103
EEEK L+EN + + E +++ +N L + + ++KL+E+ E L
Sbjct: 415 EEEKAARNALEENLKNCQSELE----RLQKDNTNLRDQLEVAKGENNKLREDVEAAKRLA 470
Query: 2102 NDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKE 1923
+ + ++ + E EEL +L+ D + +K+AL+ +E ++ L+++
Sbjct: 471 EENERLKAELEKMKKENEELMNLNNVLKSDYDSMKQALNN-------LEAEINRLQDELN 523
Query: 1922 TVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQM 1743
+E + + L+ K ES K +L EQ +L+LE +KL +L ++
Sbjct: 524 KAEEERKALLDENSNIKKQLEEAIAKNESLKAELDNVGEQLNKLKLEKDKLQEALNDMKL 583
Query: 1742 ENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSAT----- 1578
EN LK + ++ +++G + + D + EL + K+ + T
Sbjct: 584 ENDALKQNVRNLQSDLDHARKEAEDLRGAGDALRAADKDKMSELQKIKDELNNLTSEKDR 643
Query: 1577 ------DMKKVNSDAGAKVSGILEMLLPMK-------DDVFSLKEEV---LGNINSLRND 1446
D+K N + K+ ++ + MK ++ LK+E+ + ++ L+++
Sbjct: 644 LANENMDLKARNGELEKKLKDAMDQVEQMKLENADLLTEIDRLKKELDKAVNEVDRLKSE 703
Query: 1445 AQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRN 1266
++ A+++ + +L E + E+ + +AE DA+Q R+N TLQ+E
Sbjct: 704 IGSLKDAVDKCMEELEKLQTENQAVKTEIEKCKAERDALQ-------RENSTLQNEIDEL 756
Query: 1265 AKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEV 1086
K+L + K + N+M++ LE++N LK EL+ ++E +++E L +V
Sbjct: 757 RKQLNDCKTEIENLMAQKNQLETENNKLKEELN-------ACKQENEAIKAESEKLREQV 809
Query: 1085 ENLK---SELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL---- 927
++L S+L+ D+ L+ E LG H++ + +KL +DEL
Sbjct: 810 QSLNDDLSKLRGQLDIAEQKLQELE-PLGDHLQKEN----------DKLQNEIDELRKQL 858
Query: 926 --ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEED 753
NEN K + L ++ R+ ++ + E ++ G + + Q+ +D
Sbjct: 859 NDCRTENENLKAQKNQLEAENNKLREELNACKQENEAM-----KAEGEKLRGQVQSLNDD 913
Query: 752 SSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXX 573
++ L+N +L+ +K+ E + + +E ++ N+++E+++ L+D
Sbjct: 914 ---LNKLRN---QLDIAERKIEELEPLGDRLQKENDKLQNEIDELRKQLND---CRTENE 964
Query: 572 XXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXX 393
+ L+ EN +LR E+ + + K EG ++E +Q
Sbjct: 965 NLKAQKNQLEAENNKLREELNACKQENEAMK-AEGEKLRE----------QVQSLNDEVS 1013
Query: 392 XXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXX 213
++D + QE++ L+D K+ LQN ++ L+
Sbjct: 1014 KLRNQLDIAERKIQELEPLVD----------RLQKENDKLQNDLKALEDDARNLRLRLD- 1062
Query: 212 XXXKWGGI--------DMNSIEKQLKELNIHVMQLVEHNTRLKKD 102
GG+ DM +E Q+ +LN + N L+++
Sbjct: 1063 -----GGMSDNERMRNDMAMLESQVGDLNEKLKAAKAENDALQQE 1102
Score = 115 bits (287), Expect = 1e-22
Identities = 152/723 (21%), Positives = 297/723 (41%), Gaps = 72/723 (9%)
Frame = -1
Query: 2201 IEANNNLLE----QKDNI--IVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELN 2040
I++ NN LE Q+D + I L +LQE +++ L N+++ E ++ E L
Sbjct: 286 IDSLNNALEGTISQQDLLDQIAALKAELQEKDDKIQELLNELRQAE----INLLELNNLK 341
Query: 2039 RQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLK 1860
QL L+ + L+ + +++ A ++ +L KE++ K+L + + +KL +L
Sbjct: 342 SQLEELKSQLEDLELERNQLLEELAKLQNELAHTNAIKESLEKQLEVLKNDNEKLLKELD 401
Query: 1859 ALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKD-------GNEKI-- 1707
+E+ + NQL + LE ++ L+ Q +NT L+D N K+
Sbjct: 402 NANEQLLALTNQLEEEKAARNALEENLKNCQSELERLQKDNTNLRDQLEVAKGENNKLRE 461
Query: 1706 -YDLCKLLATKSREVQGQQE-------------GILKQDI--------NIEDELARTKEV 1593
+ K LA ++ ++ + E +LK D N+E E+ R ++
Sbjct: 462 DVEAAKRLAEENERLKAELEKMKKENEELMNLNNVLKSDYDSMKQALNNLEAEINRLQDE 521
Query: 1592 GRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQM 1413
A + +K D + + LE + + + + + V +N L+ + +Q AL M
Sbjct: 522 LNKAEEERKALLDENSNIKKQLEEAIAKNESLKAELDNVGEQLNKLKLEKDKLQEALNDM 581
Query: 1412 QDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARL 1233
+ E + Q V LQ+++D + +L+ L+ + EL K L
Sbjct: 582 K-------LENDALKQNVRNLQSDLDHARKEAEDLRGAGDALRAADKDKMSELQKIKDEL 634
Query: 1232 NNVMSKNINLESQNRSLKA---ELHLQAQKAFQIQEERNV-----------VESEHNVLS 1095
NN+ S+ L ++N LKA EL + + A E+ + ++ E +
Sbjct: 635 NNLTSEKDRLANENMDLKARNGELEKKLKDAMDQVEQMKLENADLLTEIDRLKKELDKAV 694
Query: 1094 SEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLR 915
+EV+ LKSE+ KD + E L ++ + +IE C+ + L R
Sbjct: 695 NEVDRLKSEIGSLKDAVDKCMEELEKLQTEN-QAVKTEIEKCKAERDALQR--------- 744
Query: 914 NENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKS---LGNGRANQREFQNKEEDSS- 747
EN+ L+NE D RK ++ + E +++ K+ N + + K+E+ +
Sbjct: 745 -ENSTLQNEI-----DELRKQLNDCKTEIENLMAQKNQLETENNKLKEELNACKQENEAI 798
Query: 746 ---------GVDLLKNKCTRLEFQV----QKLSEKAEMFETKSREAQQMANKLEEMQQTL 606
V L + ++L Q+ QKL E + + +E ++ N+++E+++ L
Sbjct: 799 KAESEKLREQVQSLNDDLSKLRGQLDIAEQKLQELEPLGDHLQKENDKLQNEIDELRKQL 858
Query: 605 SDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDT 426
+D + L+ EN +LR E+ + + K ++ ++D
Sbjct: 859 ND---CRTENENLKAQKNQLEAENNKLREELNACKQENEAMKAEGEKLRGQVQSLNDDLN 915
Query: 425 PLIQXXXXXXXXXXXKIDTRTSETQEI----DTLMDDNRKYWNRVSHFTKQTQSLQNSVQ 258
L ++D + +E+ D L +N K N + KQ + +
Sbjct: 916 KL-----------RNQLDIAERKIEELEPLGDRLQKENDKLQNEIDELRKQLNDCRTENE 964
Query: 257 ELQ 249
L+
Sbjct: 965 NLK 967
Score = 103 bits (257), Expect = 3e-19
Identities = 167/780 (21%), Positives = 336/780 (43%), Gaps = 46/780 (5%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
+E+ L + ++ +LQ + LR++ D + N NL QK+ + E
Sbjct: 929 EELEPLGDRLQKENDKLQNEIDELRKQLNDCRTE---NENLKAQKNQL-----------E 974
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQ 1944
+ + L+ ++ + +Q + + E E+L Q+ L D+V+ L+ L +A E+++Q
Sbjct: 975 AENNKLREELNACKQENEAMKAEGEKLREQVQSLNDEVSKLRNQLDIA-------ERKIQ 1027
Query: 1943 DLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQ-------LEL 1785
+LE + + KE KL +DLKAL + + + +L N++ LE
Sbjct: 1028 ELEPLVDRLQKE-------NDKLQNDLKALEDDARNLRLRLDGGMSDNERMRNDMAMLES 1080
Query: 1784 EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQE-GILKQDI----NIE 1620
++ L L+ + EN L+ N+ + KLL + Q +QE LK +I N+
Sbjct: 1081 QVGDLNEKLKAAKAENDALQQENQTLR--AKLLDMDNELSQAKQECADLKAEIADLNNLI 1138
Query: 1619 DEL-ARTKEVGRSATDMKKVNSDAGAKVSGI---LEMLLPMKDDVFSLKEEVLGNINSLR 1452
EL A+ ++ K N ++ + LE L + +LK+ +N L+
Sbjct: 1139 SELRAKIAKLEEDVEHWKLENCKLQIEIDKLKADLEKALKDLSECQALKKAQEAELNRLQ 1198
Query: 1451 ND--------AQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKN 1296
N+ A + EQ + + E A+ E A+ + LQ E++A++ L +L+ +N
Sbjct: 1199 NEKAELNKQIAGLTAQIEEQKKAAELEKSAKGESEAK-LKALQDELNALKKELEKLRMEN 1257
Query: 1295 QTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVE 1116
++E ++L ++L++ + L + N SLK EL+ + +++E + ++
Sbjct: 1258 NDYKNEMDNMKRQLSALNSQLDSCKEEIAALRATNDSLKTELNALSG----LKDEYDKLK 1313
Query: 1115 SEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASL---------------- 984
++ N L +E+ L+ + +++LE +L GQ +E+ L
Sbjct: 1314 AKVNSLENEIAGLQ---ENARNLEQERNKLRGEGDGQRIEIDKLKSALDAEKAAAGKLRS 1370
Query: 983 DIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKS 804
D+ESC+ ++L L +L ++E +L E ++ N + + AEA + +
Sbjct: 1371 DLESCQTENDRLRAQLKDLEKCKSEIDRLNAEI-------DQLNKALAAAEAKAKSLEDQ 1423
Query: 803 LGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLE 624
L N + +++ N+ + G L N LE Q K + +++A+ E
Sbjct: 1424 LSNLQDEKQQLINELNNLRGD--LSNLRNELEKQTA----------AKDKALKELADAKE 1471
Query: 623 EM---QQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRS---EMKGELTPSRSFKHREGSF 462
E+ + TL+ M +L EN +L+S E+ G+L SR+ E
Sbjct: 1472 ELNALKATLNKMRNEN----------ETLLNENEKLKSKVTELNGQLEASRN----ENEK 1517
Query: 461 IKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQT 282
+K+ N +++ + T E+ T+ + ++ +R++ +
Sbjct: 1518 LKKENENLKNEVAKL--------------------TSELATMTNKLKEAEDRLNALKNEN 1557
Query: 281 QSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKD 102
+L+N++ +L++ +N ++ +L ELN + L N +LKK+
Sbjct: 1558 DTLKNTIDKLEKAIKELEAVKMQLEQA-----LNELKPKLAELNEQLEALRNENEKLKKE 1612
Score = 92.0 bits (227), Expect = 1e-15
Identities = 152/706 (21%), Positives = 303/706 (42%), Gaps = 41/706 (5%)
Frame = -1
Query: 2240 NALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQ 2061
+AL+Q+N+ + K+ +N L Q +L ++ + S L+ + +E+ +
Sbjct: 1097 DALQQENQTLRAKLLDMDNELSQAKQECADLKAEIADLNNLISELRAKIAKLEEDVEHWK 1156
Query: 2060 TEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSR-- 1887
E +L ++ L+ D+ + LS + E +L L+N+K ++K++A ++
Sbjct: 1157 LENCKLQIEIDKLKADLEKALKDLSECQALKKAQEAELNRLQNEKAELNKQIAGLTAQIE 1216
Query: 1886 EQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKI 1707
EQK A++L+ S K ES +Q E N L+ E+EKL +MEN K+ + +
Sbjct: 1217 EQKKAAELEK-SAKGESEAKLKALQDELNA-LKKELEKL-------RMENNDYKNEMDNM 1267
Query: 1706 YDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGIL 1527
L ++ + + + + +++ EL + + +K AKV+ +
Sbjct: 1268 KRQLSALNSQLDSCKEEIAALRATNDSLKTEL-------NALSGLKDEYDKLKAKVNSLE 1320
Query: 1526 EMLLPMKDDVFSLKEE---VLGNINSLRNDAQMVQVALEQMQDTKSELFAEAE------- 1377
+ ++++ +L++E + G + R + ++ AL+ + +L ++ E
Sbjct: 1321 NEIAGLQENARNLEQERNKLRGEGDGQRIEIDKLKSALDAEKAAAGKLRSDLESCQTEND 1380
Query: 1376 -IRAQ---------EVLRLQAEVDAIQHIL--IELKRKN-----QTLQDESQRNAKELWN 1248
+RAQ E+ RL AE+D + L E K K+ LQDE Q+ EL N
Sbjct: 1381 RLRAQLKDLEKCKSEIDRLNAEIDQLNKALAAAEAKAKSLEDQLSNLQDEKQQLINELNN 1440
Query: 1247 AKARLNNVMSK-NINLESQNRSLK----AELHLQAQKAF--QIQEERNVVESEHNVLSSE 1089
+ L+N+ ++ +++++LK A+ L A KA +++ E + +E+ L S+
Sbjct: 1441 LRGDLSNLRNELEKQTAAKDKALKELADAKEELNALKATLNKMRNENETLLNENEKLKSK 1500
Query: 1088 VENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNE 909
V L +L+ S++ + E L EVA L E KL D L L+NE
Sbjct: 1501 VTELNGQLEASRNENEKLKKENENLKN---EVAKLTSELATMT-NKLKEAEDRLNALKNE 1556
Query: 908 NAKLKNEA-LYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLL 732
N LKN E E + V +A++ L K + E+ ++L
Sbjct: 1557 NDTLKNTIDKLEKAIKELEAVKMQLEQALNELKPKLAELNEQLEALRNENEKLKKENEVL 1616
Query: 731 KNKCTRLEFQV----QKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXX 564
KN+ T+L ++ KL E + E + N + + Q+ + ++
Sbjct: 1617 KNEKTKLTLELDAMTNKLKEAEDRLNALKNENDTLKNTIAQQQKAIKEL---EAAKIQLE 1673
Query: 563 IRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXX 384
++ LK EN L+ +++ + K+ + +K N +D+ ++
Sbjct: 1674 QAMKELKSENEGLKDKLEDAQNKANKLKN-DLDKLKRDNAKLQDELGKLKEEKEKADAAA 1732
Query: 383 XKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQ 246
R +E + L +N K + ++ + + L+ +++LQ+
Sbjct: 1733 KGDADRIK--KENEKLRAENAKLMDELNTCRAENEELRKQLEKLQE 1776
Score = 81.3 bits (199), Expect = 2e-12
Identities = 171/837 (20%), Positives = 330/837 (39%), Gaps = 161/837 (19%)
Frame = -1
Query: 2273 KQHTIELQENFNALRQK------NEDICLKIEA----NNNLLEQKDNIIVELSHKLQENE 2124
+ ++L+ +L+Q NED LK + + +E+ + L K+++ E
Sbjct: 68 RMERLQLESENRSLKQALQSFGVNEDEILKPDPLLIHSREEIERLQSTNATLEDKVRDLE 127
Query: 2123 E---QRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDD------ 1971
E +R + SV + + RE + LRD ++HLK L+ +D
Sbjct: 128 ETLAERDCCDDPCASVLCLREKMRYLRERFALEKKELRDMISHLKLKLAETEEDVSCPAI 187
Query: 1970 -------RAFME------KQLQDLENQKETVSKELA-----LSVSREQKLAS-------- 1869
RA M+ K DL+ + + + E+A L+ E+++
Sbjct: 188 YRLRAKLRALMKGGLDVPKNCDDLQAENDRLLAEIAELKRQLAKLDEKEITGHTSPAKSV 247
Query: 1868 ---------DLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTL----- 1731
D+ L ++ + +N + T+Q + + I+ L +L+ + L
Sbjct: 248 ETTTVPEYIDVSDLLQRLKDCENTVAGLTQQLAEKDNLIDSLNNALEGTISQQDLLDQIA 307
Query: 1730 -----LKDGNEKIYDL--------------------CKLLATKSREVQGQQEGILKQDIN 1626
L++ ++KI +L + L ++ +++ ++ +L++
Sbjct: 308 ALKAELQEKDDKIQELLNELRQAEINLLELNNLKSQLEELKSQLEDLELERNQLLEELAK 367
Query: 1625 IEDELARTKEVGRSATD----MKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINS 1458
+++ELA T + S +K N ++ E LL + + + EE N+
Sbjct: 368 LQNELAHTNAIKESLEKQLEVLKNDNEKLLKELDNANEQLLALTNQL----EEEKAARNA 423
Query: 1457 LRNDAQMVQVALEQMQDTKSELFAEAEIR-----------------AQEVLRLQAEVDAI 1329
L + + Q LE++Q + L + E+ A+E RL+AE++ +
Sbjct: 424 LEENLKNCQSELERLQKDNTNLRDQLEVAKGENNKLREDVEAAKRLAEENERLKAELEKM 483
Query: 1328 QHILIELKRKNQTLQDESQRNAKELWNAKARLNN--------------VMSKNINLESQ- 1194
+ EL N L+ + + L N +A +N ++ +N N++ Q
Sbjct: 484 KKENEELMNLNNVLKSDYDSMKQALNNLEAEINRLQDELNKAEEERKALLDENSNIKKQL 543
Query: 1193 ------NRSLKAEL--------HLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL--- 1065
N SLKAEL L+ +K ++QE N ++ E++ L V NL+S+L
Sbjct: 544 EEAIAKNESLKAELDNVGEQLNKLKLEKD-KLQEALNDMKLENDALKQNVRNLQSDLDHA 602
Query: 1064 -KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNE 888
KE++DL G G + A D S +L +I DEL L +E +L NE
Sbjct: 603 RKEAEDLRG---------AGDALRAADKDKMS------ELQKIKDELNNLTSEKDRLANE 647
Query: 887 ALYEYHDYERKN--VSGSRAEAMSVLISKSLGNG-RANQREFQNKEEDS--SGVDLLKNK 723
+ D + +N + +AM + L N + + KE D + VD LK++
Sbjct: 648 NM----DLKARNGELEKKLKDAMDQVEQMKLENADLLTEIDRLKKELDKAVNEVDRLKSE 703
Query: 722 CTRLEFQVQKLSEKAEMFETKS------------------REAQQMANKLEEMQQTLSDM 597
L+ V K E+ E +T++ RE + N+++E+++ L+D
Sbjct: 704 IGSLKDAVDKCMEELEKLQTENQAVKTEIEKCKAERDALQRENSTLQNEIDELRKQLND- 762
Query: 596 XXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLI 417
+ L+ EN +L+ E+ + + K +++ ++D + L
Sbjct: 763 --CKTEIENLMAQKNQLETENNKLKEELNACKQENEAIKAESEKLREQVQSLNDDLSKL- 819
Query: 416 QXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQ 246
++D + QE++ L D H K+ LQN + EL++
Sbjct: 820 ----------RGQLDIAEQKLQELEPLGD----------HLQKENDKLQNEIDELRK 856
Score = 62.4 bits (150), Expect = 8e-07
Identities = 70/319 (21%), Positives = 144/319 (45%), Gaps = 16/319 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLE-QKDNIIVEL---SHKLQ 2133
++ + E K EL E ALR +NE K++ N +L+ +K + +EL ++KL+
Sbjct: 1580 QLEQALNELKPKLAELNEQLEALRNENE----KLKKENEVLKNEKTKLTLELDAMTNKLK 1635
Query: 2132 ENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK 1953
E E++ +AL+N+ +++ A Q +EL + L + LK + ++
Sbjct: 1636 EAEDRLNALKNENDTLKNTIAQQQKAIKELEAAKIQLEQAMKELK-------SENEGLKD 1688
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEE----STKNQLLIQTEQNKQLEL 1785
+L+D +N+ + +L KL +L L E++E + K ++N++L
Sbjct: 1689 KLEDAQNKANKLKNDLDKLKRDNAKLQDELGKLKEEKEKADAAAKGDADRIKKENEKLRA 1748
Query: 1784 EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 1605
E KL L + EN L+ EK+ + L K+ VQ ++ I + +E+E
Sbjct: 1749 ENAKLMDELNTCRAENEELRKQLEKLQEEIDKL-KKAAGVQRVRDYIKYLEGKVEEE--- 1804
Query: 1604 TKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRN-------- 1449
++G D +++ V+ +L+ + +++ +EE+ + L+
Sbjct: 1805 -PKIG-DQLDELEIDPQMREDVADLLKRSQSLSENIHQTEEEIRNIADVLKQLKVCAFDP 1862
Query: 1448 DAQMVQVALEQMQDTKSEL 1392
D+ + + L Q+ D ++
Sbjct: 1863 DSWLNSLTLTQLADLHDKI 1881
>ref|XP_006560777.1| PREDICTED: sporulation-specific protein 15 isoform X2 [Apis
mellifera]
Length = 1934
Score = 125 bits (313), Expect = 1e-25
Identities = 164/712 (23%), Positives = 297/712 (41%), Gaps = 41/712 (5%)
Frame = -1
Query: 2258 ELQENFNALRQKNEDICLK---IEANNNLLEQK-DNIIVELSHKLQENEEQRSALQNDMQ 2091
ELQ+N L+ +N ++ + + ++ LE K DN+ EL EN + R+ + N
Sbjct: 527 ELQQNMQNLKTENGELKKENDDLRTRSSELEHKLDNVKKELDKVESENADLRAKIDN--- 583
Query: 2090 SVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSK 1911
+ E E+ +++ L+ +++ LK+AL VD+ MEK + E K+ K
Sbjct: 584 --------LEKELEKDKKEIEQLKLEISSLKDALDKCVDE---MEKLKVENEKLKKEGMK 632
Query: 1910 ELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLY-----GSLQMKQ 1746
A + L + L E +T N+L +N L E+ +L G ++ Q
Sbjct: 633 VEATWLEENVNLKAKNTELEENLANTVNELDKMRSENADLLSELNRLKQELESGRKEIDQ 692
Query: 1745 MENTL--LKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTK----EVGRS 1584
+++ + +KD K D + L T++++++ + +G+ + + +E+A K E+
Sbjct: 693 LKSEIGSMKDALGKCVDEIEKLKTENKDLKSEVQGLESERDRLTNEVADLKPKISELQEK 752
Query: 1583 ATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEV---LGNINSLRNDAQMVQVALEQM 1413
TD K +A + S + + +K ++ S +E+ +NSL+N +E++
Sbjct: 753 LTDASKKLDEAKTEDSDLRAEVDRLKKELESAGKEIDQLKAEMNSLKNGLNKCVEEMEKL 812
Query: 1412 QDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARL 1233
+ SEL +V L+ E D++ L +K +N L+DE + K+L K
Sbjct: 813 TNENSEL-------KSQVHGLRGEGDSLASELTNVKDENSALKDEKDQLNKQLAENKTEN 865
Query: 1232 NNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESK 1053
+ +N LES+N +K EL + E N ++ E+N L E+E L +LK
Sbjct: 866 ERLKKQNDELESENTKIKKELE-------SCKNENNNLKEENNKLKEELEKLGEQLKSLN 918
Query: 1052 DLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEY 873
D E LR +++ + R EK +EL LRNE +LK + E
Sbjct: 919 D-ETNKLRRELKEAEDKIQILEPQLSRARSENEKSQ---NELAVLRNEANELKVKLDREM 974
Query: 872 HDYERKNVSGSRAEAMSVLISKSLGNGR-------ANQREFQNKEEDSSGVDL-LKNKCT 717
D + E + ++K L N R ++ + K D+ V L LK +C
Sbjct: 975 LDNTNMRNALKILEDQVLDLNKKLDNCREENDALKEENKDLKTKLSDTGQVVLNLKTECD 1034
Query: 716 RLEFQVQKLSEKAEMFETK--SREAQQMANKLE-------------EMQQTLSDMXXXXX 582
L+ + L + E + K +EA+ K+E ++++ L D+
Sbjct: 1035 NLKEDIASLQKTIEQLKQKIADQEAEIDHWKVEHCKFELDNEKLKADLEKVLKDLNECQI 1094
Query: 581 XXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXX 402
+ LK E L M +LT + R S E + D D +
Sbjct: 1095 AKKAIESDLIKLKNEKDDLNKNMT-DLTSQLDRQKR--SLEAEKSAKDRGDVQIASLN-- 1149
Query: 401 XXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQ 246
+ +E++ L DN KY + + KQ S +N + + ++
Sbjct: 1150 ---------SELEALKKELEKLRADNSKYKSEIDDLGKQLASAKNELNDCRE 1192
Score = 118 bits (295), Expect = 1e-23
Identities = 164/772 (21%), Positives = 320/772 (41%), Gaps = 28/772 (3%)
Frame = -1
Query: 2255 LQENFNALRQKNEDICLKIEA-NNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQ 2079
L+ LR+ E+I ++ + L E+ D II L K + E +S ++ +++
Sbjct: 207 LEPELYELRESKEEIMEELNMMRDTLKERNDQIIQILEDKAKLEEYYKSKVETLEAKLDE 266
Query: 2078 MHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELAL 1899
++S E E+L +L +D + L D +EK+L +LE ++ + KEL
Sbjct: 267 QASLS-AELEDLRNEL----EDQRAKNKELEACCKDMDALEKKLSELEKKRSELEKELED 321
Query: 1898 S---VSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLL 1728
+ + R QK DLK + E E + K++L E++K+L+ + E L+ L+ + EN L
Sbjct: 322 NRGELERLQKENLDLKDVIEVERAEKDKLRDLLEESKKLKEDNENLWAQLERLRGENDDL 381
Query: 1727 KDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAG 1548
+ + DL K L + ++ + + ++ +EL+ + + D +
Sbjct: 382 MGQKKALEDLNKQLNEDNESMKRTMGNLEARIDSLSNELSNVERERDALLDENE------ 435
Query: 1547 AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRA 1368
V LE L +++ + ++ ++ L+ + +Q + M+ E E
Sbjct: 436 -SVKRELERTLTENENLKTELDKADEQLDKLKTERNELQRNFDTMK-------LENETLK 487
Query: 1367 QEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNR 1188
+ V L+ +++ + + E+K L+D+ + E + + N+ ++N L+ +N
Sbjct: 488 ENVKALKDDLEESKREVDEMKAVGDALKDKEELKDAEFRELQQNMQNLKTENGELKKEND 547
Query: 1187 SLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLG 1008
L+ K +++E + VESE+ L ++++NL+ EL++ K
Sbjct: 548 DLRTRSSELEHKLDNVKKELDKVESENADLRAKIDNLEKELEKDK--------------- 592
Query: 1007 QHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEA 828
+ +E L+I S + A +K +DE+ L+ EN KLK E + + +NV
Sbjct: 593 KEIEQLKLEISSLKDALDK---CVDEMEKLKVENEKLKKEGMKVEATWLEENV------- 642
Query: 827 MSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREA 648
N +A E + L N L+ + SE A++ +R
Sbjct: 643 ----------NLKAKNTELEEN---------LANTVNELD---KMRSENADLLSELNRLK 680
Query: 647 QQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREG 468
Q++ + +E+ Q S++ + LK EN L+SE++G L R E
Sbjct: 681 QELESGRKEIDQLKSEIGSMKDALGKCVDEIEKLKTENKDLKSEVQG-LESERDRLTNEV 739
Query: 467 SFIK----EINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQ----EIDTLMDDNRKYW 312
+ +K E+ D + + ++D E + EID L +
Sbjct: 740 ADLKPKISELQEKLTDASKKLDEAKTEDSDLRAEVDRLKKELESAGKEIDQLKAEMNSLK 799
Query: 311 NRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGI-DMNS--------IEKQLK 159
N ++ ++ + L N EL+ + + D NS + KQL
Sbjct: 800 NGLNKCVEEMEKLTNENSELKSQVHGLRGEGDSLASELTNVKDENSALKDEKDQLNKQLA 859
Query: 158 E-------LNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEE 24
E L +L NT++KK+++ + N ++L + KLK + E
Sbjct: 860 ENKTENERLKKQNDELESENTKIKKELE---SCKNENNNLKEENNKLKEELE 908
Score = 109 bits (273), Expect = 5e-21
Identities = 158/762 (20%), Positives = 314/762 (41%), Gaps = 77/762 (10%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKI----EANNNLLEQKDNIIVELSHKL 2136
+E+ +L E EL+ + LR + + + ++ + N+ L ++KD + +L+
Sbjct: 807 EEMEKLTNENS----ELKSQVHGLRGEGDSLASELTNVKDENSALKDEKDQLNKQLAENK 862
Query: 2135 QENE-----------------EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVN 2007
ENE ++ + +N+ ++++ + + E E+L QL L D+ N
Sbjct: 863 TENERLKKQNDELESENTKIKKELESCKNENNNLKEENNKLKEELEKLGEQLKSLNDETN 922
Query: 2006 HLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKN 1827
L+ L A D +E QL ++ E ELA+ + +L L + +N
Sbjct: 923 KLRRELKEAEDKIQILEPQLSRARSENEKSQNELAVLRNEANELKVKLDREMLDNTNMRN 982
Query: 1826 QLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEG 1647
L I +Q L +++ + EN KD K+ D +++ E +E
Sbjct: 983 ALKILEDQVLDLNKKLDNCREENDALKEEN---KDLKTKLSDTGQVVLNLKTECDNLKED 1039
Query: 1646 ILKQDINIED---ELA-RTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEE 1479
I IE ++A + E+ + K D K+ LE +L ++ K+
Sbjct: 1040 IASLQKTIEQLKQKIADQEAEIDHWKVEHCKFELD-NEKLKADLEKVLKDLNECQIAKKA 1098
Query: 1478 VLGNINSLRNDAQMVQVAL----EQMQDTKSELFAEAEIRAQ---EVLRLQAEVDAIQHI 1320
+ ++ L+N+ + + Q+ K L AE + + ++ L +E++A++
Sbjct: 1099 IESDLIKLKNEKDDLNKNMTDLTSQLDRQKRSLEAEKSAKDRGDVQIASLNSELEALKKE 1158
Query: 1319 LIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQI 1140
L +L+ N + E K+L +AK LN+ + + L++ N +L++EL
Sbjct: 1159 LEKLRADNSKYKSEIDDLGKQLASAKNELNDCREEIVVLKNANSALRSEL---------- 1208
Query: 1139 QEERNVVESEHNVLSSEVENLKSE----LKESKDLEGYFLRLFEILLGQHVEVASL---- 984
+ ++ +++ L++E++ LKSE L++ + LE F +L GQ VE+ L
Sbjct: 1209 -DPLRSLKDDYSRLTTELDGLKSENTKLLQDKRSLEDEFGKLRGEGDGQRVEIDRLRTTL 1267
Query: 983 ------------DIESCRFAEEKLMRILDE----LICLRNENAKLKNEALYEYHDYERKN 852
D++SC+ +KL ++E L + EN +LK E D RK
Sbjct: 1268 DAEKTAAEKLKSDLQSCKDENDKLQTQINEMKRSLDKMGTENDRLKREV-----DESRKK 1322
Query: 851 VSGSRAEAMSVL------------ISKSLGNGRANQREFQNKEEDSSGV-DLLKNKCTRL 711
+ A+ S+ + K L R + +N+ E +GV D ++ + T L
Sbjct: 1323 LEDMEAKVKSLENQLSNLSAEKEELVKELYRTREDLNNLRNELEKQTGVKDTMEKESTNL 1382
Query: 710 EFQVQKLSEKAEMFETKSREAQQMANKLE-EMQQTLSDMXXXXXXXXXXXIRVRSLKKEN 534
+ +++ L E+ ++ + +KL E+ + + + +L + N
Sbjct: 1383 KEELKALKEELNKTRDENDRLKNENDKLNAEIARLNKQLDALKDESANLKNDIENLNERN 1442
Query: 533 TRLRSEMK-------GELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKI 375
L E+ G T + K +E +K I ED + ++
Sbjct: 1443 AELSKELAVAKDNLMGMETRLSNLK-KENDDMKNKIITLEDSIQEVDDLKRQLKEAKKEL 1501
Query: 374 DTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQ 249
D + E+DTL N+K + + + ++ +L+N + LQ
Sbjct: 1502 D---KPSPELDTLKSTNKKLQDDLDNARNESLNLKNDLDNLQ 1540
Score = 104 bits (259), Expect = 2e-19
Identities = 120/579 (20%), Positives = 269/579 (46%), Gaps = 13/579 (2%)
Frame = -1
Query: 2300 EVSRL---YEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQE 2130
E+ RL + EK +L+ + + + +N+ + +I L++ L ++ E
Sbjct: 1259 EIDRLRTTLDAEKTAAEKLKSDLQSCKDENDKLQTQINEMKRSLDKMGTENDRLKREVDE 1318
Query: 2129 NEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQ 1950
+ ++ ++ ++S+E + E+EEL ++L R+D+N+L+ L EKQ
Sbjct: 1319 SRKKLEDMEAKVKSLENQLSNLSAEKEELVKELYRTREDLNNLRNEL----------EKQ 1368
Query: 1949 LQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKL 1770
K+T+ KE L +LKAL E+ T+++ +N +L EI +L
Sbjct: 1369 ----TGVKDTMEKE-------STNLKEELKALKEELNKTRDENDRLKNENDKLNAEIARL 1417
Query: 1769 YGSLQMKQMENTLLKDG----NEKIYDLCKLLATKSREVQGQQ---EGILKQDINIEDEL 1611
L + E+ LK+ NE+ +L K LA + G + + K++ ++++++
Sbjct: 1418 NKQLDALKDESANLKNDIENLNERNAELSKELAVAKDNLMGMETRLSNLKKENDDMKNKI 1477
Query: 1610 ARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQ 1431
++ + D+K+ +A + L+ P D + S +++ ++++ RN++ ++
Sbjct: 1478 ITLEDSIQEVDDLKRQLKEAKKE----LDKPSPELDTLKSTNKKLQDDLDNARNESLNLK 1533
Query: 1430 VALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELW 1251
L+ +Q+ + L E +E + A++ L+ +KR+N+ L ++++ EL
Sbjct: 1534 NDLDNLQNDYNNLQTELADVKEERDTFRERAAALEKDLVRVKRENEELVEQNETLRTELD 1593
Query: 1250 NAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKS 1071
+ + N ++ + L+S+N L+ L + +++E+ N ++ +++ L +++ +
Sbjct: 1594 DCRGENNRLLKELEKLKSENVKLQDNLINARSEGERLKEDLNKLKKDYSDLRTDLTKARE 1653
Query: 1070 ELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKN 891
+ K+ + + + L + ++ S D+ C+ EKL + ++ L+ EN KLK
Sbjct: 1654 DRDVRKEKDMELDKEIDELKAVNAKLKS-DLYDCQKENEKLRK---QVTKLKAENDKLK- 1708
Query: 890 EALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRL 711
+AL + D + + + + + AN+ +N E GV L++ L
Sbjct: 1709 KALDKDLDQKETEIDKDILDDCNEYV-------EANKILRKNFENQLKGVQRLRDYINYL 1761
Query: 710 EFQ--VQKLSEKAEMFETKSR-EAQQMANKLEEMQQTLS 603
+ + K+++K E E + A++ L +M Q LS
Sbjct: 1762 DGKGTEPKMADKLEESEMNNPVNAKKDIEDLLKMSQDLS 1800
Score = 93.2 bits (230), Expect = 4e-16
Identities = 135/651 (20%), Positives = 277/651 (42%), Gaps = 31/651 (4%)
Frame = -1
Query: 2273 KQHTIELQENF-------NALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQR 2115
K EL+EN + +R +N D+ ++ N L ++ ++ E+ E +
Sbjct: 645 KAKNTELEENLANTVNELDKMRSENADLLSEL---NRLKQELESGRKEIDQLKSEIGSMK 701
Query: 2114 SALQNDMQSVEQMHAVS----------QTEREELNRQLVLLRDDVNHLKEALSMAVDDRA 1965
AL + +E++ + ++ER+ L ++ L+ ++ L+E L+ A
Sbjct: 702 DALGKCVDEIEKLKTENKDLKSEVQGLESERDRLTNEVADLKPKISELQEKLTDASKKLD 761
Query: 1964 FMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLEL 1785
+ + DL + + + KEL + +L +++ +L ++ T +N +L+
Sbjct: 762 EAKTEDSDLRAEVDRLKKELESAGKEIDQLKAEMNSLKNGLNKCVEEMEKLTNENSELKS 821
Query: 1784 EIEKLYGS-------LQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDIN 1626
++ L G L + EN+ LKD ++ L K LA E + + E + KQ+
Sbjct: 822 QVHGLRGEGDSLASELTNVKDENSALKDEKDQ---LNKQLA----ENKTENERLKKQNDE 874
Query: 1625 IEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRND 1446
+E E + K + K N++ + + + E L + + + SL +E N LR +
Sbjct: 875 LESENTKIK---KELESCKNENNNLKEENNKLKEELEKLGEQLKSLNDET----NKLRRE 927
Query: 1445 AQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRN 1266
+ + ++ ++ S +E E E+ L+ E + +++K + L + + RN
Sbjct: 928 LKEAEDKIQILEPQLSRARSENEKSQNELAVLRNEANE-----LKVKLDREMLDNTNMRN 982
Query: 1265 A-----KELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNV 1101
A ++ + +L+N +N L+ +N+ LK +L Q ++ E + ++ +
Sbjct: 983 ALKILEDQVLDLNKKLDNCREENDALKEENKDLKTKLSDTGQVVLNLKTECDNLKEDIAS 1042
Query: 1100 LSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFA--EEKLMRILDEL 927
L +E LK ++ + Q E+ +E C+F EKL L+++
Sbjct: 1043 LQKTIEQLKQKIAD-----------------QEAEIDHWKVEHCKFELDNEKLKADLEKV 1085
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSS 747
+ NE ++ +A+ E + KN + M+ L S+ R+ + E K+
Sbjct: 1086 LKDLNE-CQIAKKAI-ESDLIKLKNEKDDLNKNMTDLTSQLDRQKRSLEAEKSAKDRGDV 1143
Query: 746 GVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXX 567
+ L ++ L+ +++KL +A+ + KS E + +L + L+D
Sbjct: 1144 QIASLNSELEALKKELEKL--RADNSKYKS-EIDDLGKQLASAKNELND----------C 1190
Query: 566 XIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQ 414
+ LK N+ LRS EL P RS K E++ ++T L+Q
Sbjct: 1191 REEIVVLKNANSALRS----ELDPLRSLKDDYSRLTTELDGLKSENTKLLQ 1237
>gb|EGI67148.1| Cytochrome P450 6B3 [Acromyrmex echinatior]
Length = 2102
Score = 125 bits (313), Expect = 1e-25
Identities = 159/794 (20%), Positives = 344/794 (43%), Gaps = 52/794 (6%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQ 2103
++ K+ +L L+++ +++ K+ + NN + VEL++KL+E + L+
Sbjct: 595 DDGKEELTKLLSEIETLKKEVDNMSNKLTSANNEVVDLQQKSVELNNKLKEAQVINEQLR 654
Query: 2102 NDMQSVE----QMHAVSQTEREELNR----------QLVLLRDDVNHLKEALSMAVDDRA 1965
D+ +E ++A R+E +R Q+ LL D+VN L+E L A +
Sbjct: 655 ADIHQIEAENKDINAQMNNYRDENSRLNIKLNESKEQINLLTDEVNKLREQLDNAENRIK 714
Query: 1964 FMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLEL 1785
F+E QL L+ K+ + E+ + KL DL A S + + +L+ + K L L
Sbjct: 715 FLEAQLVSLQTDKDKMQNEINALQNEISKLKLDLSAESTAKRDIQEELVALKNEMKNLIL 774
Query: 1784 EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 1605
+I+++ + E LLK + + L + E+ Q + +++ +L++
Sbjct: 775 KIDEMRVQNHALKEERDLLKKELLNLGEESLSLRAANAEMMNQINNLKLDISDLQSQLSK 834
Query: 1604 TKE----------VGRSATDMKKVNSDAGAKVSGILEM-LLPMKDDVFSLKEEVL---GN 1467
+E + +TD + ++ + + ++ ++ ++ +L+ E + G
Sbjct: 835 AEEDIEYWKLENCKLKMSTDKLSIENEKKKEALNVCKVEHQTLEKEITNLRNEKIKLEGE 894
Query: 1466 INSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTL 1287
I L+N + + ++ + K E E EV+ L+ E+ ++ L +L+ +N +
Sbjct: 895 IAELKNLLEGLNLSSFAEKSAKEEAVKELTKFKNEVVALREELQTLKSELTKLRTENDKI 954
Query: 1286 QDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEH 1107
+D+ ++ + ++ K L N ++ + L N +LK++++ + +E N ++SE
Sbjct: 955 RDKEEKLSSQVSTLKTELENAKNEILALRVDNDTLKSKIN-------TLTDENNKLKSES 1007
Query: 1106 NVLSSEVENLKSELKESKDLEGYFLRLFEILL----GQHVEVASLDIESCRFAEEKLM-R 942
N+L SEV+ LK E ++ F + F+ L GQ E+ +L +S AE+KL +
Sbjct: 1008 NMLISEVDGLKLENTNMREERQKFEKEFDKLKGEDDGQKDEIKNL--KSNLTAEQKLSEK 1065
Query: 941 ILDELICLRNENAKLK----------------NEAL-YEYHDYERKNVSG-SRAEAMSVL 816
I EL ++EN +L+ N+ L E D ++ ++ ++ A+
Sbjct: 1066 IRLELSTSQSENDRLRAELEKLQKNLDTLELVNDKLNSEVEDLKKTSIDAQNKVNALQYH 1125
Query: 815 ISKSLGNGRANQREFQNKEEDSSGV-DLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQM 639
+++ L A +E + + S + ++ +K + + + + ++ E E +M
Sbjct: 1126 VAELLEEKEALLKELDSLRAEVSRLGKVVSDKVAKEAIEKKTIDSNGKLIEELKAELDKM 1185
Query: 638 ANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFI 459
+ E +++ L+D+ SLK EN L+ E T SFK S +
Sbjct: 1186 RVENENLKRKLNDVNKQHI----------SLKDENAALKIENTKIATELDSFK----SDL 1231
Query: 458 KEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQ 279
+ +E T + + T E Q++ LM +N++ +++ +
Sbjct: 1232 NRCRVDNERLTIELAASEARALEIQRE-RTDDKERQDLQNLMVENKELRDKLRMAQNEIN 1290
Query: 278 SLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDV 99
L+ ++++ + D++S E +LK+ I + + ++D+
Sbjct: 1291 KLKENIKKSKGDFIEDAD------------DIDSFENELKKSMIEI-------DKAREDL 1331
Query: 98 KFGFAWANSMHDLN 57
K+ N + +N
Sbjct: 1332 KYAAEENNKLKMIN 1345
Score = 78.2 bits (191), Expect = 1e-11
Identities = 121/593 (20%), Positives = 245/593 (41%), Gaps = 34/593 (5%)
Frame = -1
Query: 2189 NNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDV 2010
N L+ + + E L+E+ +R + + V+ + R+ + +RD +
Sbjct: 110 NERLQNANEELAEKVRNLEESLAERDCCDDPCEKVKYVREKIAALRDRFAAEKKQMRDTI 169
Query: 2009 NHLKEALSMAVDDRAF-----MEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEK 1845
+HLK L A +D + + +L++L + +++++ V R + + DL E
Sbjct: 170 SHLKLKLMEAEEDTSCAALNRLRAKLRELMKDGQKADQQVSVVVERSMQTSVDLSKSYED 229
Query: 1844 EESTKNQLLIQTEQNKQLELEI---EKLYGSLQMKQMEN----TLLKDGNEKIYDLCKLL 1686
T+ T+ + LE + E++ L K+ + + L++ + +L L
Sbjct: 230 LLRTERLQAEPTQIRRTLEEVVTFSEEIDVPLSAKEEDIPALLSQLRNCKMLLAELKMHL 289
Query: 1685 ATKSREVQGQQEGILKQDINIEDELARTKE-VGRSATD----MKKVNSDAGAKVSGILEM 1521
K+ + Q + K +I + E + RSA D MK+ ++ I E+
Sbjct: 290 DEKTAYTEALQSELNKLKASIVIPMVDLDEMIVRSAMDEVAEMKEEPEKPDKEIRKIQEL 349
Query: 1520 LLPMKDDVFSLKEEVLGNINSLRNDAQMVQVA---LEQMQDTKSELFAEAEIRAQEVLRL 1350
++D +K E+ LR + + QVA LE M+D L AE E + +
Sbjct: 350 SRVQEEDN-EMKSEIDKLNVDLRREEEKFQVAQKELEGMRDDLHSLGAENEFLKETLENA 408
Query: 1349 QAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAEL 1170
+ E + ELK +N L++ KEL +++ NN+ + L S+N+ L+ EL
Sbjct: 409 KLETN-------ELKEENVALKNNLDNMIKELESSRRENNNIKTDLDQLLSENKYLRDEL 461
Query: 1169 HLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKD-------------LEGYFLR 1029
Q + Q++ E + + L E++ LK E + KD E L+
Sbjct: 462 EKQVAETDQLKSEGIAWKEGFDKLLQEMDRLKVESDKLKDESATVKSERDNLTTERDNLK 521
Query: 1028 LFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNV 849
LL + ++ ++ + K + +E++ + A + N L D + +
Sbjct: 522 SENGLLKDDLSKINVALDDAKKQLNK-FEVENEVLTEELKKANVNNNKLLADFDTLQSEM 580
Query: 848 SGSRAEAMSVLISKSLGNGRANQREFQNKEED-SSGVDLLKNKCTRLEFQVQKLSEKAEM 672
+ ++E +L + + +G+ + ++ E VD + NK T +V L +K+
Sbjct: 581 AKLKSENRKLL--QEVDDGKEELTKLLSEIETLKKEVDNMSNKLTSANNEVVDLQQKSVE 638
Query: 671 FETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEM 513
K +EAQ + +L +D+ ++ + + EN+RL ++
Sbjct: 639 LNNKLKEAQVINEQLR------ADIHQIEAENKDINAQMNNYRDENSRLNIKL 685
>ref|XP_006560776.1| PREDICTED: sporulation-specific protein 15 isoform X1 [Apis
mellifera]
Length = 2064
Score = 125 bits (313), Expect = 1e-25
Identities = 164/712 (23%), Positives = 297/712 (41%), Gaps = 41/712 (5%)
Frame = -1
Query: 2258 ELQENFNALRQKNEDICLK---IEANNNLLEQK-DNIIVELSHKLQENEEQRSALQNDMQ 2091
ELQ+N L+ +N ++ + + ++ LE K DN+ EL EN + R+ + N
Sbjct: 657 ELQQNMQNLKTENGELKKENDDLRTRSSELEHKLDNVKKELDKVESENADLRAKIDN--- 713
Query: 2090 SVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSK 1911
+ E E+ +++ L+ +++ LK+AL VD+ MEK + E K+ K
Sbjct: 714 --------LEKELEKDKKEIEQLKLEISSLKDALDKCVDE---MEKLKVENEKLKKEGMK 762
Query: 1910 ELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLY-----GSLQMKQ 1746
A + L + L E +T N+L +N L E+ +L G ++ Q
Sbjct: 763 VEATWLEENVNLKAKNTELEENLANTVNELDKMRSENADLLSELNRLKQELESGRKEIDQ 822
Query: 1745 MENTL--LKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTK----EVGRS 1584
+++ + +KD K D + L T++++++ + +G+ + + +E+A K E+
Sbjct: 823 LKSEIGSMKDALGKCVDEIEKLKTENKDLKSEVQGLESERDRLTNEVADLKPKISELQEK 882
Query: 1583 ATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEV---LGNINSLRNDAQMVQVALEQM 1413
TD K +A + S + + +K ++ S +E+ +NSL+N +E++
Sbjct: 883 LTDASKKLDEAKTEDSDLRAEVDRLKKELESAGKEIDQLKAEMNSLKNGLNKCVEEMEKL 942
Query: 1412 QDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARL 1233
+ SEL +V L+ E D++ L +K +N L+DE + K+L K
Sbjct: 943 TNENSEL-------KSQVHGLRGEGDSLASELTNVKDENSALKDEKDQLNKQLAENKTEN 995
Query: 1232 NNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESK 1053
+ +N LES+N +K EL + E N ++ E+N L E+E L +LK
Sbjct: 996 ERLKKQNDELESENTKIKKELE-------SCKNENNNLKEENNKLKEELEKLGEQLKSLN 1048
Query: 1052 DLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEY 873
D E LR +++ + R EK +EL LRNE +LK + E
Sbjct: 1049 D-ETNKLRRELKEAEDKIQILEPQLSRARSENEKSQ---NELAVLRNEANELKVKLDREM 1104
Query: 872 HDYERKNVSGSRAEAMSVLISKSLGNGR-------ANQREFQNKEEDSSGVDL-LKNKCT 717
D + E + ++K L N R ++ + K D+ V L LK +C
Sbjct: 1105 LDNTNMRNALKILEDQVLDLNKKLDNCREENDALKEENKDLKTKLSDTGQVVLNLKTECD 1164
Query: 716 RLEFQVQKLSEKAEMFETK--SREAQQMANKLE-------------EMQQTLSDMXXXXX 582
L+ + L + E + K +EA+ K+E ++++ L D+
Sbjct: 1165 NLKEDIASLQKTIEQLKQKIADQEAEIDHWKVEHCKFELDNEKLKADLEKVLKDLNECQI 1224
Query: 581 XXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXX 402
+ LK E L M +LT + R S E + D D +
Sbjct: 1225 AKKAIESDLIKLKNEKDDLNKNMT-DLTSQLDRQKR--SLEAEKSAKDRGDVQIASLN-- 1279
Query: 401 XXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQ 246
+ +E++ L DN KY + + KQ S +N + + ++
Sbjct: 1280 ---------SELEALKKELEKLRADNSKYKSEIDDLGKQLASAKNELNDCRE 1322
Score = 118 bits (295), Expect = 1e-23
Identities = 164/772 (21%), Positives = 320/772 (41%), Gaps = 28/772 (3%)
Frame = -1
Query: 2255 LQENFNALRQKNEDICLKIEA-NNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQ 2079
L+ LR+ E+I ++ + L E+ D II L K + E +S ++ +++
Sbjct: 337 LEPELYELRESKEEIMEELNMMRDTLKERNDQIIQILEDKAKLEEYYKSKVETLEAKLDE 396
Query: 2078 MHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELAL 1899
++S E E+L +L +D + L D +EK+L +LE ++ + KEL
Sbjct: 397 QASLS-AELEDLRNEL----EDQRAKNKELEACCKDMDALEKKLSELEKKRSELEKELED 451
Query: 1898 S---VSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLL 1728
+ + R QK DLK + E E + K++L E++K+L+ + E L+ L+ + EN L
Sbjct: 452 NRGELERLQKENLDLKDVIEVERAEKDKLRDLLEESKKLKEDNENLWAQLERLRGENDDL 511
Query: 1727 KDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAG 1548
+ + DL K L + ++ + + ++ +EL+ + + D +
Sbjct: 512 MGQKKALEDLNKQLNEDNESMKRTMGNLEARIDSLSNELSNVERERDALLDENE------ 565
Query: 1547 AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRA 1368
V LE L +++ + ++ ++ L+ + +Q + M+ E E
Sbjct: 566 -SVKRELERTLTENENLKTELDKADEQLDKLKTERNELQRNFDTMK-------LENETLK 617
Query: 1367 QEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNR 1188
+ V L+ +++ + + E+K L+D+ + E + + N+ ++N L+ +N
Sbjct: 618 ENVKALKDDLEESKREVDEMKAVGDALKDKEELKDAEFRELQQNMQNLKTENGELKKEND 677
Query: 1187 SLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLG 1008
L+ K +++E + VESE+ L ++++NL+ EL++ K
Sbjct: 678 DLRTRSSELEHKLDNVKKELDKVESENADLRAKIDNLEKELEKDK--------------- 722
Query: 1007 QHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEA 828
+ +E L+I S + A +K +DE+ L+ EN KLK E + + +NV
Sbjct: 723 KEIEQLKLEISSLKDALDK---CVDEMEKLKVENEKLKKEGMKVEATWLEENV------- 772
Query: 827 MSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREA 648
N +A E + L N L+ + SE A++ +R
Sbjct: 773 ----------NLKAKNTELEEN---------LANTVNELD---KMRSENADLLSELNRLK 810
Query: 647 QQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREG 468
Q++ + +E+ Q S++ + LK EN L+SE++G L R E
Sbjct: 811 QELESGRKEIDQLKSEIGSMKDALGKCVDEIEKLKTENKDLKSEVQG-LESERDRLTNEV 869
Query: 467 SFIK----EINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQ----EIDTLMDDNRKYW 312
+ +K E+ D + + ++D E + EID L +
Sbjct: 870 ADLKPKISELQEKLTDASKKLDEAKTEDSDLRAEVDRLKKELESAGKEIDQLKAEMNSLK 929
Query: 311 NRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGI-DMNS--------IEKQLK 159
N ++ ++ + L N EL+ + + D NS + KQL
Sbjct: 930 NGLNKCVEEMEKLTNENSELKSQVHGLRGEGDSLASELTNVKDENSALKDEKDQLNKQLA 989
Query: 158 E-------LNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEE 24
E L +L NT++KK+++ + N ++L + KLK + E
Sbjct: 990 ENKTENERLKKQNDELESENTKIKKELE---SCKNENNNLKEENNKLKEELE 1038
Score = 109 bits (273), Expect = 5e-21
Identities = 158/762 (20%), Positives = 314/762 (41%), Gaps = 77/762 (10%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKI----EANNNLLEQKDNIIVELSHKL 2136
+E+ +L E EL+ + LR + + + ++ + N+ L ++KD + +L+
Sbjct: 937 EEMEKLTNENS----ELKSQVHGLRGEGDSLASELTNVKDENSALKDEKDQLNKQLAENK 992
Query: 2135 QENE-----------------EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVN 2007
ENE ++ + +N+ ++++ + + E E+L QL L D+ N
Sbjct: 993 TENERLKKQNDELESENTKIKKELESCKNENNNLKEENNKLKEELEKLGEQLKSLNDETN 1052
Query: 2006 HLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKN 1827
L+ L A D +E QL ++ E ELA+ + +L L + +N
Sbjct: 1053 KLRRELKEAEDKIQILEPQLSRARSENEKSQNELAVLRNEANELKVKLDREMLDNTNMRN 1112
Query: 1826 QLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEG 1647
L I +Q L +++ + EN KD K+ D +++ E +E
Sbjct: 1113 ALKILEDQVLDLNKKLDNCREENDALKEEN---KDLKTKLSDTGQVVLNLKTECDNLKED 1169
Query: 1646 ILKQDINIED---ELA-RTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEE 1479
I IE ++A + E+ + K D K+ LE +L ++ K+
Sbjct: 1170 IASLQKTIEQLKQKIADQEAEIDHWKVEHCKFELD-NEKLKADLEKVLKDLNECQIAKKA 1228
Query: 1478 VLGNINSLRNDAQMVQVAL----EQMQDTKSELFAEAEIRAQ---EVLRLQAEVDAIQHI 1320
+ ++ L+N+ + + Q+ K L AE + + ++ L +E++A++
Sbjct: 1229 IESDLIKLKNEKDDLNKNMTDLTSQLDRQKRSLEAEKSAKDRGDVQIASLNSELEALKKE 1288
Query: 1319 LIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQI 1140
L +L+ N + E K+L +AK LN+ + + L++ N +L++EL
Sbjct: 1289 LEKLRADNSKYKSEIDDLGKQLASAKNELNDCREEIVVLKNANSALRSEL---------- 1338
Query: 1139 QEERNVVESEHNVLSSEVENLKSE----LKESKDLEGYFLRLFEILLGQHVEVASL---- 984
+ ++ +++ L++E++ LKSE L++ + LE F +L GQ VE+ L
Sbjct: 1339 -DPLRSLKDDYSRLTTELDGLKSENTKLLQDKRSLEDEFGKLRGEGDGQRVEIDRLRTTL 1397
Query: 983 ------------DIESCRFAEEKLMRILDE----LICLRNENAKLKNEALYEYHDYERKN 852
D++SC+ +KL ++E L + EN +LK E D RK
Sbjct: 1398 DAEKTAAEKLKSDLQSCKDENDKLQTQINEMKRSLDKMGTENDRLKREV-----DESRKK 1452
Query: 851 VSGSRAEAMSVL------------ISKSLGNGRANQREFQNKEEDSSGV-DLLKNKCTRL 711
+ A+ S+ + K L R + +N+ E +GV D ++ + T L
Sbjct: 1453 LEDMEAKVKSLENQLSNLSAEKEELVKELYRTREDLNNLRNELEKQTGVKDTMEKESTNL 1512
Query: 710 EFQVQKLSEKAEMFETKSREAQQMANKLE-EMQQTLSDMXXXXXXXXXXXIRVRSLKKEN 534
+ +++ L E+ ++ + +KL E+ + + + +L + N
Sbjct: 1513 KEELKALKEELNKTRDENDRLKNENDKLNAEIARLNKQLDALKDESANLKNDIENLNERN 1572
Query: 533 TRLRSEMK-------GELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKI 375
L E+ G T + K +E +K I ED + ++
Sbjct: 1573 AELSKELAVAKDNLMGMETRLSNLK-KENDDMKNKIITLEDSIQEVDDLKRQLKEAKKEL 1631
Query: 374 DTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQ 249
D + E+DTL N+K + + + ++ +L+N + LQ
Sbjct: 1632 D---KPSPELDTLKSTNKKLQDDLDNARNESLNLKNDLDNLQ 1670
Score = 104 bits (259), Expect = 2e-19
Identities = 120/579 (20%), Positives = 269/579 (46%), Gaps = 13/579 (2%)
Frame = -1
Query: 2300 EVSRL---YEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQE 2130
E+ RL + EK +L+ + + + +N+ + +I L++ L ++ E
Sbjct: 1389 EIDRLRTTLDAEKTAAEKLKSDLQSCKDENDKLQTQINEMKRSLDKMGTENDRLKREVDE 1448
Query: 2129 NEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQ 1950
+ ++ ++ ++S+E + E+EEL ++L R+D+N+L+ L EKQ
Sbjct: 1449 SRKKLEDMEAKVKSLENQLSNLSAEKEELVKELYRTREDLNNLRNEL----------EKQ 1498
Query: 1949 LQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKL 1770
K+T+ KE L +LKAL E+ T+++ +N +L EI +L
Sbjct: 1499 ----TGVKDTMEKE-------STNLKEELKALKEELNKTRDENDRLKNENDKLNAEIARL 1547
Query: 1769 YGSLQMKQMENTLLKDG----NEKIYDLCKLLATKSREVQGQQ---EGILKQDINIEDEL 1611
L + E+ LK+ NE+ +L K LA + G + + K++ ++++++
Sbjct: 1548 NKQLDALKDESANLKNDIENLNERNAELSKELAVAKDNLMGMETRLSNLKKENDDMKNKI 1607
Query: 1610 ARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQ 1431
++ + D+K+ +A + L+ P D + S +++ ++++ RN++ ++
Sbjct: 1608 ITLEDSIQEVDDLKRQLKEAKKE----LDKPSPELDTLKSTNKKLQDDLDNARNESLNLK 1663
Query: 1430 VALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELW 1251
L+ +Q+ + L E +E + A++ L+ +KR+N+ L ++++ EL
Sbjct: 1664 NDLDNLQNDYNNLQTELADVKEERDTFRERAAALEKDLVRVKRENEELVEQNETLRTELD 1723
Query: 1250 NAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKS 1071
+ + N ++ + L+S+N L+ L + +++E+ N ++ +++ L +++ +
Sbjct: 1724 DCRGENNRLLKELEKLKSENVKLQDNLINARSEGERLKEDLNKLKKDYSDLRTDLTKARE 1783
Query: 1070 ELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKN 891
+ K+ + + + L + ++ S D+ C+ EKL + ++ L+ EN KLK
Sbjct: 1784 DRDVRKEKDMELDKEIDELKAVNAKLKS-DLYDCQKENEKLRK---QVTKLKAENDKLK- 1838
Query: 890 EALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRL 711
+AL + D + + + + + AN+ +N E GV L++ L
Sbjct: 1839 KALDKDLDQKETEIDKDILDDCNEYV-------EANKILRKNFENQLKGVQRLRDYINYL 1891
Query: 710 EFQ--VQKLSEKAEMFETKSR-EAQQMANKLEEMQQTLS 603
+ + K+++K E E + A++ L +M Q LS
Sbjct: 1892 DGKGTEPKMADKLEESEMNNPVNAKKDIEDLLKMSQDLS 1930
Score = 93.2 bits (230), Expect = 4e-16
Identities = 135/651 (20%), Positives = 277/651 (42%), Gaps = 31/651 (4%)
Frame = -1
Query: 2273 KQHTIELQENF-------NALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQR 2115
K EL+EN + +R +N D+ ++ N L ++ ++ E+ E +
Sbjct: 775 KAKNTELEENLANTVNELDKMRSENADLLSEL---NRLKQELESGRKEIDQLKSEIGSMK 831
Query: 2114 SALQNDMQSVEQMHAVS----------QTEREELNRQLVLLRDDVNHLKEALSMAVDDRA 1965
AL + +E++ + ++ER+ L ++ L+ ++ L+E L+ A
Sbjct: 832 DALGKCVDEIEKLKTENKDLKSEVQGLESERDRLTNEVADLKPKISELQEKLTDASKKLD 891
Query: 1964 FMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLEL 1785
+ + DL + + + KEL + +L +++ +L ++ T +N +L+
Sbjct: 892 EAKTEDSDLRAEVDRLKKELESAGKEIDQLKAEMNSLKNGLNKCVEEMEKLTNENSELKS 951
Query: 1784 EIEKLYGS-------LQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDIN 1626
++ L G L + EN+ LKD ++ L K LA E + + E + KQ+
Sbjct: 952 QVHGLRGEGDSLASELTNVKDENSALKDEKDQ---LNKQLA----ENKTENERLKKQNDE 1004
Query: 1625 IEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRND 1446
+E E + K + K N++ + + + E L + + + SL +E N LR +
Sbjct: 1005 LESENTKIK---KELESCKNENNNLKEENNKLKEELEKLGEQLKSLNDET----NKLRRE 1057
Query: 1445 AQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRN 1266
+ + ++ ++ S +E E E+ L+ E + +++K + L + + RN
Sbjct: 1058 LKEAEDKIQILEPQLSRARSENEKSQNELAVLRNEANE-----LKVKLDREMLDNTNMRN 1112
Query: 1265 A-----KELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNV 1101
A ++ + +L+N +N L+ +N+ LK +L Q ++ E + ++ +
Sbjct: 1113 ALKILEDQVLDLNKKLDNCREENDALKEENKDLKTKLSDTGQVVLNLKTECDNLKEDIAS 1172
Query: 1100 LSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFA--EEKLMRILDEL 927
L +E LK ++ + Q E+ +E C+F EKL L+++
Sbjct: 1173 LQKTIEQLKQKIAD-----------------QEAEIDHWKVEHCKFELDNEKLKADLEKV 1215
Query: 926 ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSS 747
+ NE ++ +A+ E + KN + M+ L S+ R+ + E K+
Sbjct: 1216 LKDLNE-CQIAKKAI-ESDLIKLKNEKDDLNKNMTDLTSQLDRQKRSLEAEKSAKDRGDV 1273
Query: 746 GVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXX 567
+ L ++ L+ +++KL +A+ + KS E + +L + L+D
Sbjct: 1274 QIASLNSELEALKKELEKL--RADNSKYKS-EIDDLGKQLASAKNELND----------C 1320
Query: 566 XIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQ 414
+ LK N+ LRS EL P RS K E++ ++T L+Q
Sbjct: 1321 REEIVVLKNANSALRS----ELDPLRSLKDDYSRLTTELDGLKSENTKLLQ 1367
>ref|XP_001582404.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121916639|gb|EAY21418.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 2120
Score = 124 bits (310), Expect = 2e-25
Identities = 152/724 (20%), Positives = 313/724 (43%), Gaps = 47/724 (6%)
Frame = -1
Query: 2279 EEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQN 2100
EE Q+TI+ +N N K + + NN+L ++ +N+ E+ + + LQN
Sbjct: 1337 EELQNTIDKLQNSNKSPNKLQ------QENNSLKQEIENLKEEIEQNNKSKSYSPNKLQN 1390
Query: 2099 DMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFM----------EKQ 1950
+ +S++Q + Q E EEL + L+ + + LK S++ + EK
Sbjct: 1391 ENESLKQENEKLQEEIEELQNTVEKLQQENDLLKNNKSVSPSPKKLQNENNSLKQENEKL 1450
Query: 1949 LQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKL 1770
+++E + T+ K L S +KL + K++ +N+ E+N++L+ EIE+L
Sbjct: 1451 QEEIEELQNTIDK-LQNSNKSPKKLQQENKSMLNSPNKLQNEYETLQEENEKLQDEIEEL 1509
Query: 1769 YGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKE-V 1593
+++ Q EN LLK+ K ++ + +Q + + +++ +++E+ + + +
Sbjct: 1510 QSTVEKLQQENDLLKNSKS------KSVSPSPKRLQQENNSLKQENEKLQEEINQLQNTI 1563
Query: 1592 GRSATDMKKVNSDAGAKVSGILEMLL----PMKDDVFSLKEE-------------VLGNI 1464
+ + K+ S + K+ E L +++ + L++E +
Sbjct: 1564 EKLQNNKSKLYSPSPKKLQNENESLKQENEKLQEQIEKLQQENDSKPKYSPSPRKLQQEN 1623
Query: 1463 NSLRNDAQMVQVALEQMQDT---------KSELFAEAEIRAQ-EVLRLQAEVDAIQHILI 1314
NSL+ + + +Q ++Q+Q+T KS+ + Q E LQ E D +Q +
Sbjct: 1624 NSLKQENEKLQEEIDQLQNTIEKLQQENNKSKSLLNTPNKLQNEYETLQEENDKLQDKIE 1683
Query: 1313 ELKRKNQTLQDESQ--RNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQI 1140
EL+ + LQ E++ +N K +++ + + ++N +L+ +N L+ E+ ++
Sbjct: 1684 ELQSTIEKLQQENEELKNNKPIYSPSPK--KLQNENNSLKQENEKLQEEIEELQNTIDKL 1741
Query: 1139 QEER---NVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESC 969
Q E N ++ E+N L E+ENLK E++++ + Y + + + S
Sbjct: 1742 QIENKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSPKKLQ-----------QENNSL 1790
Query: 968 RFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGR 789
+ EKL +DE L+N KL+NE + E + E S + +
Sbjct: 1791 KQENEKLQEEIDE---LQNTVDKLQNENNLQSLQEENDKLQDEIEELQSTVEKLQ----Q 1843
Query: 788 ANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQT 609
N+ NK S L+N+ L+ + +KL E ++EE+Q T
Sbjct: 1844 ENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQE-----------------EIEELQNT 1886
Query: 608 LSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFK----HREGSFIKEINIG 441
+ + SLK+E L+ E++ + S+S+ +E + +K+ N
Sbjct: 1887 IDKLQIENKSPNKLQQENNSLKQEIENLKEEIE-QNNKSKSYSPKKLQQENNSLKQENEK 1945
Query: 440 DEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSV 261
+++ +Q +D +E + +L ++N K + + + LQ
Sbjct: 1946 LQEEIDELQ----------NTVDKLQNE-NNLQSLQEENDKLQDEIEELQSTVEKLQQEN 1994
Query: 260 QELQ 249
+EL+
Sbjct: 1995 EELK 1998
Score = 122 bits (307), Expect = 5e-25
Identities = 161/796 (20%), Positives = 344/796 (43%), Gaps = 119/796 (14%)
Frame = -1
Query: 2279 EEKQHTIE-----------LQENFNALRQKNEDICLKIEANN-------NLLEQKDNIIV 2154
EE Q+TI+ LQ+ N+L+Q+ E++ +IE NN N L+ ++ +
Sbjct: 922 EELQNTIDKLQNSNKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSPNKLQNENESLK 981
Query: 2153 ELSHKLQENEEQRSALQNDMQSVEQMHAVSQTER------EELNRQLVLLRDDVNHLKEA 1992
+ + KLQE E+ LQN ++ ++Q + + + + ++L ++ LL+++ +
Sbjct: 982 QENEKLQEQIEE---LQNTVEKLQQENDLLKNNKSVSPSPKKLQQENDLLKNNKSVSPSP 1038
Query: 1991 LSMAVDDRAFM---EKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQL 1821
+ ++ + EK +++E + T+ K L S +KL + K++ +N+
Sbjct: 1039 KKLQNENNSLKQENEKLQEEIEELQNTIDK-LQNSNKSPKKLQQENKSMLNSPNKLQNEY 1097
Query: 1820 LIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGIL 1641
E+N++L+ EIE+L +++ Q EN LLK+ K ++ + +Q + +
Sbjct: 1098 ETLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKS------KSVSPSPKRLQQENNSLK 1151
Query: 1640 KQDINIEDELARTKE-VGRSATDMKKVNSDAGAKVSGILEMLL----PMKDDVFSLKEE- 1479
+++ +++E+ + + + + + K+ S + K+ E L +++ + L++E
Sbjct: 1152 QENEKLQEEINQLQNTIEKLQNNKSKLYSPSPKKLQNENESLKQENEKLQEQIEKLQQEN 1211
Query: 1478 ------------VLGNINSLRNDAQMVQVALEQMQDT---------KSELFAEAEIRAQ- 1365
+ NSL+ + + +Q ++Q+Q+T KS+ + Q
Sbjct: 1212 DSKPKYSPSPRKLQQENNSLKQENEKLQEEIDQLQNTIEKLQQENNKSKSLLNTPNKLQN 1271
Query: 1364 EVLRLQAEVDAIQHILIELKRKNQTLQDESQ--RNAKELWNAKARLNNVMSKNINLESQN 1191
E LQ E D +Q + EL+ + LQ E++ +N K +++ + + ++N +L+ +N
Sbjct: 1272 EYETLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPK--KLQNENNSLKQEN 1329
Query: 1190 RSLKAELHLQAQKAFQIQEER---NVVESEHNVLSSEVENLKSELKESKDLEGYF---LR 1029
L+ E+ ++Q N ++ E+N L E+ENLK E++++ + Y L+
Sbjct: 1330 EKLQEEIEELQNTIDKLQNSNKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSPNKLQ 1389
Query: 1028 LFEILLGQHVEVASLDIESCRFAEEKLM-----------------RILDELICLRNENAK 900
L Q E +IE + EKL ++ +E L+ EN K
Sbjct: 1390 NENESLKQENEKLQEEIEELQNTVEKLQQENDLLKNNKSVSPSPKKLQNENNSLKQENEK 1449
Query: 899 LKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKC 720
L+ E + ++ S + + L + Q E++ +E++ + L+++
Sbjct: 1450 LQEEIEELQNTIDKLQNSNKSPKKLQQENKSMLNSPNKLQNEYETLQEEN---EKLQDEI 1506
Query: 719 TRLEFQVQKLSEKAEMF--------------------------ETKSREAQQMANKLEEM 618
L+ V+KL ++ ++ E E Q+ N +E++
Sbjct: 1507 EELQSTVEKLQQENDLLKNSKSKSVSPSPKRLQQENNSLKQENEKLQEEINQLQNTIEKL 1566
Query: 617 QQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEM---------KGELTPSRSFKHREGS 465
Q S + SLK+EN +L+ ++ K + +PS +E +
Sbjct: 1567 QNNKSKLYSPSPKKLQNEN--ESLKQENEKLQEQIEKLQQENDSKPKYSPSPRKLQQENN 1624
Query: 464 FIKEIN--IGDEDD--TPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSH 297
+K+ N + +E D I+ ++T E +TL ++N K +++
Sbjct: 1625 SLKQENEKLQEEIDQLQNTIEKLQQENNKSKSLLNTPNKLQNEYETLQEENDKLQDKIEE 1684
Query: 296 FTKQTQSLQNSVQELQ 249
+ LQ +EL+
Sbjct: 1685 LQSTIEKLQQENEELK 1700
Score = 110 bits (276), Expect = 2e-21
Identities = 126/591 (21%), Positives = 266/591 (45%), Gaps = 9/591 (1%)
Frame = -1
Query: 2255 LQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQM 2076
LQ+ N+L+Q+NE + +I N +E+ N +K + LQN+ +S++Q
Sbjct: 1538 LQQENNSLKQENEKLQEEINQLQNTIEKLQN------NKSKLYSPSPKKLQNENESLKQ- 1590
Query: 2075 HAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKE---L 1905
E E+L Q+ L+ + N K S + ++++ L+ + E + +E L
Sbjct: 1591 ------ENEKLQEQIEKLQQE-NDSKPKYSPSPRK---LQQENNSLKQENEKLQEEIDQL 1640
Query: 1904 ALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLK 1725
++ + Q+ + K+L +N+ E+N +L+ +IE+L +++ Q EN LK
Sbjct: 1641 QNTIEKLQQENNKSKSLLNTPNKLQNEYETLQEENDKLQDKIEELQSTIEKLQQENEELK 1700
Query: 1724 DGNEKIYDLC-KLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAG 1548
+ N+ IY K L ++ ++ + E + ++ +++ + + + +S +++ N+
Sbjct: 1701 N-NKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQIENKSPNKLQQENNSLK 1759
Query: 1547 AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRA 1368
++ + E + +++ NSL+ + + +Q ++++Q+T +L E +++
Sbjct: 1760 QEIENLKEEIEQNNKSKSYSPKKLQQENNSLKQENEKLQEEIDELQNTVDKLQNENNLQS 1819
Query: 1367 QEVLRLQAEVDAIQHILIELKRKNQTLQDESQ--RNAKELWNAKARLNNVMSKNINLESQ 1194
LQ E D +Q + EL+ + LQ E++ +N K +++ + + ++N +L+ +
Sbjct: 1820 -----LQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPK--KLQNENNSLKQE 1872
Query: 1193 NRSLKAELHLQAQKAFQIQEER---NVVESEHNVLSSEVENLKSELKESKDLEGYFLRLF 1023
N L+ E+ ++Q E N ++ E+N L E+ENLK E++++ + Y +
Sbjct: 1873 NEKLQEEIEELQNTIDKLQIENKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSPKKL 1932
Query: 1022 EILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSG 843
+ + S + EKL +DEL +N KL+NE + E +
Sbjct: 1933 Q-----------QENNSLKQENEKLQEEIDEL---QNTVDKLQNENNLQSLQEENDKLQD 1978
Query: 842 SRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFET 663
E S + + N+ NK S L+N+ L+ + +KL E+
Sbjct: 1979 EIEELQSTVEKLQ----QENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEE------ 2028
Query: 662 KSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK 510
+EE+Q T+ + SLK+E L+ E++
Sbjct: 2029 -----------IEELQNTIDKLQIENKSPNKLQQENNSLKQEIENLKEEIE 2068
Score = 106 bits (265), Expect = 4e-20
Identities = 145/723 (20%), Positives = 310/723 (42%), Gaps = 38/723 (5%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
K++ E KQ +LQE L+Q+N D K + L+Q++N + + + KLQE
Sbjct: 1184 KKLQNENESLKQENEKLQEQIEKLQQEN-DSKPKYSPSPRKLQQENNSLKQENEKLQEEI 1242
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQ 1944
+Q LQN ++ ++Q + S++ N+ L+++ L+E D+ ++ ++
Sbjct: 1243 DQ---LQNTIEKLQQENNKSKSLLNTPNK----LQNEYETLQEENDKLQDEIEELQSTVE 1295
Query: 1943 DLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYG 1764
L+ + E + + +KL ++ +L ++ E + E+ ++L+ I+KL
Sbjct: 1296 KLQQENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQ-------EEIEELQNTIDKLQN 1348
Query: 1763 SLQMK---QMENTLLKDG----NEKIYDLCKLLATKSREVQGQQEGILKQDINIE---DE 1614
S + Q EN LK E+I K + ++Q + E + +++ ++ +E
Sbjct: 1349 SNKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSPNKLQNENESLKQENEKLQEEIEE 1408
Query: 1613 LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEV---LGNINSLRN-- 1449
L T E + D+ K N + +K + L+EE+ I+ L+N
Sbjct: 1409 LQNTVEKLQQENDLLKNNKSVSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSN 1468
Query: 1448 -DAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQ 1272
+ +Q + M ++ ++L E E +E +LQ E++ +Q + +L+++N L+
Sbjct: 1469 KSPKKLQQENKSMLNSPNKLQNEYETLQEENEKLQDEIEELQSTVEKLQQENDLLK---- 1524
Query: 1271 RNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSS 1092
N+K++ +V L+ +N SLK Q+ ++QEE N +++ L +
Sbjct: 1525 -------NSKSK--SVSPSPKRLQQENNSLK-------QENEKLQEEINQLQNTIEKLQN 1568
Query: 1091 EVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRN 912
L S + E L+ L + +E + +S ++ E L+
Sbjct: 1569 NKSKLYSPSPKKLQNENESLKQENEKLQEQIEKLQQENDSKPKYSPSPRKLQQENNSLKQ 1628
Query: 911 ENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLL 732
EN KL+ E + E+ ++++++ L Q E++ +E++ D L
Sbjct: 1629 ENEKLQEEIDQLQNTIEKLQQENNKSKSL-------LNTPNKLQNEYETLQEEN---DKL 1678
Query: 731 KNKCTRLEFQVQKLSEKAEMFETK------------------SREAQQMANKLEEMQQTL 606
++K L+ ++KL ++ E + +E +++ ++EE+Q T+
Sbjct: 1679 QDKIEELQSTIEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTI 1738
Query: 605 SDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFK----HREGSFIKEINIGD 438
+ SLK+E L+ E++ + S+S+ +E + +K+ N
Sbjct: 1739 DKLQIENKSPNKLQQENNSLKQEIENLKEEIE-QNNKSKSYSPKKLQQENNSLKQENEKL 1797
Query: 437 EDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQ 258
+++ +Q +D +E + +L ++N K + + + LQ +
Sbjct: 1798 QEEIDELQ----------NTVDKLQNE-NNLQSLQEENDKLQDEIEELQSTVEKLQQENE 1846
Query: 257 ELQ 249
EL+
Sbjct: 1847 ELK 1849
Score = 106 bits (265), Expect = 4e-20
Identities = 90/416 (21%), Positives = 203/416 (48%), Gaps = 9/416 (2%)
Frame = -1
Query: 2258 ELQENFNALRQKNEDICLK---IEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQS 2088
ELQ L+Q+NE++ + L+ ++N + + + KLQE E+ LQN +
Sbjct: 1684 ELQSTIEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIEE---LQNTIDK 1740
Query: 2087 VEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKE 1908
++ + +L ++ L+ ++ +LKE + +++ K+LQ N + +++
Sbjct: 1741 LQ----IENKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSPKKLQQENNSLKQENEK 1796
Query: 1907 LALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLL 1728
L + Q L+ +N L E+N +L+ EIE+L +++ Q EN L
Sbjct: 1797 LQEEIDELQNTVDKLQ--------NENNLQSLQEENDKLQDEIEELQSTVEKLQQENEEL 1848
Query: 1727 KDGNEKIYDLC-KLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDA 1551
K+ N+ IY K L ++ ++ + E + ++ +++ + + + +S +++ N+
Sbjct: 1849 KN-NKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQIENKSPNKLQQENNSL 1907
Query: 1550 GAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIR 1371
++ + E + +++ NSL+ + + +Q ++++Q+T +L E ++
Sbjct: 1908 KQEIENLKEEIEQNNKSKSYSPKKLQQENNSLKQENEKLQEEIDELQNTVDKLQNENNLQ 1967
Query: 1370 AQEVLRLQAEVDAIQHILIELKRKNQTLQDESQ--RNAKELWNAKARLNNVMSKNINLES 1197
+ LQ E D +Q + EL+ + LQ E++ +N K +++ + + ++N +L+
Sbjct: 1968 S-----LQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPK--KLQNENNSLKQ 2020
Query: 1196 QNRSLKAELHLQAQKAFQIQEER---NVVESEHNVLSSEVENLKSELKESKDLEGY 1038
+N L+ E+ ++Q E N ++ E+N L E+ENLK E++++ + Y
Sbjct: 2021 ENEKLQEEIEELQNTIDKLQIENKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSY 2076
Score = 99.4 bits (246), Expect = 6e-18
Identities = 159/809 (19%), Positives = 330/809 (40%), Gaps = 131/809 (16%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQ 2103
E++ + L + K EDI + N+LL+ K V + + Q+N+ Q+ ++
Sbjct: 674 EQKVDNLTNLNNELTINQMKYEDI----KEENDLLKNKSASPVSATPRTQQNKIQQLQMR 729
Query: 2102 ND--MQSVEQMHAV-------------SQT----------EREELNR-------QLVLLR 2019
ND +E +H S+T E E LN Q+++L+
Sbjct: 730 NDELKTEIEILHQTIDKLTSARIKDNDSKTVDNEIDLLKKENERLNAMLDDSSMQIIMLQ 789
Query: 2018 DDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQ---KLASDLKALSE 1848
+++ K +++ +++Q+++L+ + K + S +Q KL +++ L
Sbjct: 790 QEIDENKSNSLKQENEK--LQEQIEELQKHSPSPKKLQQENNSLKQENEKLQEEIEELQN 847
Query: 1847 KEESTKNQLLIQT--EQNKQLELEIEKLYGSLQMKQMENTLLKDG--------------- 1719
+ +N+ +Q+ E+N +L+ EIE+L +++ Q EN LK+
Sbjct: 848 TVDKLQNENNLQSLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNEN 907
Query: 1718 ------NEKIYDLCKLL---------ATKSREVQGQQEGILKQDI-NIEDELAR-TKEVG 1590
NEK+ + + L + KS Q+ LKQ+I N+++E+ + K
Sbjct: 908 NSLKQENEKLQEQIEELQNTIDKLQNSNKSPNKLQQENNSLKQEIENLKEEIEQNNKSKS 967
Query: 1589 RSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEE--VLGNINSLRNDAQMVQVALEQ 1416
S ++ N + + E + +++ V L++E +L N S+ + +Q +
Sbjct: 968 YSPNKLQNENESLKQENEKLQEQIEELQNTVEKLQQENDLLKNNKSVSPSPKKLQQENDL 1027
Query: 1415 MQDTKS------ELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKEL 1254
+++ KS +L E QE +LQ E++ +Q+ + +L+ N++ + Q N K +
Sbjct: 1028 LKNNKSVSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSPKKLQQEN-KSM 1086
Query: 1253 WNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNV---------------V 1119
N+ +L N L+ +N L+ E+ ++Q+E ++ +
Sbjct: 1087 LNSPNKLQNEYE---TLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKSKSVSPSPKRL 1143
Query: 1118 ESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRI 939
+ E+N L E E L+ E+ + ++ L + + ES + EKL
Sbjct: 1144 QQENNSLKQENEKLQEEINQLQNTIEKLQNNKSKLYSPSPKKLQNENESLKQENEKLQEQ 1203
Query: 938 LDEL----------------ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISK 807
+++L + N + K +NE L E D + + + E SK
Sbjct: 1204 IEKLQQENDSKPKYSPSPRKLQQENNSLKQENEKLQEEIDQLQNTIEKLQQENNK---SK 1260
Query: 806 SLGN-GRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETK---------- 660
SL N Q E++ +E++ D L+++ L+ V+KL ++ E +
Sbjct: 1261 SLLNTPNKLQNEYETLQEEN---DKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKK 1317
Query: 659 --------SREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGE 504
+E +++ ++EE+Q T+ + SLK+E L+ E++ +
Sbjct: 1318 LQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSPNKLQQENNSLKQEIENLKEEIE-Q 1376
Query: 503 LTPSRSFK----HREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTL 336
S+S+ E +K+ N +++ +Q + S + L
Sbjct: 1377 NNKSKSYSPNKLQNENESLKQENEKLQEEIEELQNTVEKLQQENDLLKNNKSVSPSPKKL 1436
Query: 335 MDDNRKYWNRVSHFTKQTQSLQNSVQELQ 249
++N ++ + LQN++ +LQ
Sbjct: 1437 QNENNSLKQENEKLQEEIEELQNTIDKLQ 1465
Score = 82.0 bits (201), Expect = 1e-12
Identities = 147/780 (18%), Positives = 319/780 (40%), Gaps = 46/780 (5%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQE-NFNALRQKNE---------DICLK-----IEANNNLLEQK 2169
+E+ R +EE TI L N L+ + E D+ +K +E +N +K
Sbjct: 260 EELQRKAQEENTKTISLLNIQINQLQNQLEKAYSGKQADDVAVKKNIADLERSN---AEK 316
Query: 2168 DNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEAL 1989
D +I LS K+ EE+ S L+ + E+ +E+L +Q+ + ++ +
Sbjct: 317 DVVIQSLSTKVGRFEEKVSNLEAKISEYEKTIKQLNNSKEDLQKQINNFSNKIDIERAEK 376
Query: 1988 SMAVDDRAFMEKQLQ--DLENQKETVS----------KELALSVSRE-----QKLASDLK 1860
+ +++ +++Q+Q +++ QKE K + LS + E Q L ++
Sbjct: 377 QIYIENNNDLKEQIQNDEIKFQKERKEFQQELENLRIKFVQLSNNTEKDNLIQHLQEEIN 436
Query: 1859 ALSEK--EESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLL 1686
AL +K E S + T + E I L + M ++EN +K E YD +
Sbjct: 437 ALRQKLSEYSKIVENSKSTPGKESYESTITNLRTQINMLKLENQEIKKDIEN-YDTMEKQ 495
Query: 1685 ATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMK 1506
+ ++ LK++ + + +L K + D+K+ D ILE+ +
Sbjct: 496 NEEMKKQMDDLRSQLKENKDYQSQLENMKLIQEENDDLKERIGDMSNLSDQILELKKKLN 555
Query: 1505 DDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQ 1326
D + KE + I++L D + E+ T S++ ++ ++ Q + + ++ + I
Sbjct: 556 DSE-NEKEILRKQIDNLCKDDE------EEDVPTFSKVISDLKVENQILKKKISDSEQIS 608
Query: 1325 HILIELKRKNQ---TLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKA---ELHL 1164
+LK++ +++E+ E+ + + + +N +E QN LK +LH+
Sbjct: 609 KENEDLKKQINEYIDIENENDELKDEISTLQNNIQKITERNEEIEKQNDDLKKNNDDLHV 668
Query: 1163 QAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASL 984
+ Q + + +E + + E++K E K+ + ++ +
Sbjct: 669 KIHNLEQKVDNLTNLNNELTINQMKYEDIKEENDLLKNKSASPVSATPRTQQNKIQQLQM 728
Query: 983 DIESCRFAEEKLMRILDELICLR---NENAKLKNEALYEYHDYERKNVSGSRAEAMSVLI 813
+ + E L + +D+L R N++ + NE + ER N + +++
Sbjct: 729 RNDELKTEIEILHQTIDKLTSARIKDNDSKTVDNEIDLLKKENERLNAMLDDSSMQIIML 788
Query: 812 SKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMAN 633
+ + ++N + +N++ +L K+ + + Q + S K +E +++
Sbjct: 789 QQEIDENKSNSLKQENEKLQEQIEELQKHSPSPKKLQQENNSLK--------QENEKLQE 840
Query: 632 KLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKE 453
++EE+Q T+ + ++SL++EN +L+ E++ EL + +E +K
Sbjct: 841 EIEELQNTVDKL--------QNENNLQSLQEENDKLQDEIE-ELQSTVEKLQQENEELKN 891
Query: 452 INIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQE-IDTLMDDNRKYWNRVSHFTKQTQS 276
+Q K+ + E Q ID L + N+ Q
Sbjct: 892 NKPIYSPSPKKLQNENNSLKQENEKLQEQIEELQNTIDKLQNSNKSPNKLQQENNSLKQE 951
Query: 275 LQNSVQELQQXXXXXXXXXXXXXXKWGGI--DMNSIEKQLKELNIHVMQLVEHNTRLKKD 102
++N +E++Q + + + +++Q++EL V +L + N LK +
Sbjct: 952 IENLKEEIEQNNKSKSYSPNKLQNENESLKQENEKLQEQIEELQNTVEKLQQENDLLKNN 1011
Score = 62.8 bits (151), Expect = 6e-07
Identities = 68/312 (21%), Positives = 138/312 (44%), Gaps = 30/312 (9%)
Frame = -1
Query: 2303 KEVSRLYEE--EKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQE 2130
+E +L EE E Q+T++ +N N L+ E+ N+ L ++ + + + QE
Sbjct: 1792 QENEKLQEEIDELQNTVDKLQNENNLQSLQEE-------NDKLQDEIEELQSTVEKLQQE 1844
Query: 2129 NEEQRS----------ALQNDMQSVEQMHAVSQTEREELNRQLVLL-------------- 2022
NEE ++ LQN+ S++Q + Q E EEL + L
Sbjct: 1845 NEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQIENKSPNKLQQEN 1904
Query: 2021 ---RDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALS 1851
+ ++ +LKE + +++ K+LQ N + +++L + Q L+
Sbjct: 1905 NSLKQEIENLKEEIEQNNKSKSYSPKKLQQENNSLKQENEKLQEEIDELQNTVDKLQ--- 1961
Query: 1850 EKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLC-KLLATKS 1674
+N L E+N +L+ EIE+L +++ Q EN LK+ N+ IY K L ++
Sbjct: 1962 -----NENNLQSLQEENDKLQDEIEELQSTVEKLQQENEELKN-NKPIYSPSPKKLQNEN 2015
Query: 1673 REVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVF 1494
++ + E + ++ +++ + + + +S +++ N+ +K ++
Sbjct: 2016 NSLKQENEKLQEEIEELQNTIDKLQIENKSPNKLQQENNS--------------LKQEIE 2061
Query: 1493 SLKEEVLGNINS 1458
+LKEE+ N S
Sbjct: 2062 NLKEEIEQNNKS 2073
>ref|XP_001330650.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121897262|gb|EAY02389.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 1662
Score = 120 bits (301), Expect = 3e-24
Identities = 160/804 (19%), Positives = 344/804 (42%), Gaps = 55/804 (6%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQ 2103
+E KQ EL++ + + NED+ +E +NL ++ + I +L +++EN+E +
Sbjct: 650 DELKQKLKELEQKYKDTEKSNEDLKKLLEQVDNLQKESEKINQDLEKQIEENQENSDVDE 709
Query: 2102 NDM--QSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQ 1929
N++ Q V ++ + E+E+LN +L +D+ E L + A+ E + ++++ +
Sbjct: 710 NEILKQKVTELES-EVKEKEKLNEELKKENEDLKKEVENL----QENAWNETENEEIKEK 764
Query: 1928 KETVSKELALSVSREQKLASDLK---ALSEKEESTKN---------------QLLIQTEQ 1803
E ++ L V K +DLK + SE E+S KN I E+
Sbjct: 765 LEKENEILQKQVEENNKTLNDLKQKLSESENEKSVKNSENDKLKQKVTEIESDFKISNEK 824
Query: 1802 NKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQE-------GI 1644
+ L+ +++ L +L+ + E + + N+K+ L + +Q Q +
Sbjct: 825 SSNLQQKLDVLSQNLEKLEKEMKISSEKNQKLQKENSDLQNQFTSLQKQNSDNQLKITSL 884
Query: 1643 LKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLG-- 1470
LK+ +E++L + +K D K++ E + ++++V +++ G
Sbjct: 885 LKEKSELENQLNENSTQNLESNSSEKEIRDLKEKITKQNEKIKELEEEVKKGYQDLWGAD 944
Query: 1469 -NINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQ 1293
+ +S D ++ + LE + K+ L + ++ ++ + I+ + I+L++K++
Sbjct: 945 SDDDSKEKDEEIKNLKLEIEKINKNHLEKIGIVEKEKKNEIEKRENKIKKMRIDLQKKDE 1004
Query: 1292 ---TLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNV 1122
L E +N K+ W+ ++ + +L+ +N +K E+ + ++ +IQ++ +
Sbjct: 1005 EINKLNKEISQNKKDEWSTVTFGDD--EEISSLKKENERIKQEITEKQKEIEEIQQKLSK 1062
Query: 1121 VESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMR 942
E+ SSE+ LK E +E + L L Q +E + + ++K+
Sbjct: 1063 FTKENEEKSSEISLLKKENEEKLSV----LEKENEELKQRIEEFNSFKKENEENKQKIYN 1118
Query: 941 I-------LDELICLRNENAKLK-------NEALYEYHDYERK--NVSGSRAEAMSVLIS 810
+ L+E+ L+ EN +LK E + D+ K N E +SVL
Sbjct: 1119 LGEETKKKLNEISVLKKENEELKQKLNEINEEMKQKIVDFNEKFSNSKKENEEKLSVL-K 1177
Query: 809 KSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANK 630
K N + EF + ++S +NK Q+L++ E ETK ++ + +
Sbjct: 1178 KENDNLKQKLNEFNSFMKESE-----ENK--------QRLNDLGE--ETK-KKLSILKKE 1221
Query: 629 LEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEI 450
EEM+Q +SD+ ++ K+ N RL +K + E +F +EI
Sbjct: 1222 NEEMKQNISDL-------------MKENKELNERLSKSIKENEENKKKLNENELNFKQEI 1268
Query: 449 NIG------DEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTK 288
+E++ + +I E +++ ++ N + ++ K
Sbjct: 1269 EENSLLKKENEENKQKLNEINQEMKKKLNEISNLKRENEDLKRSLNGNEEIIEEMNEINK 1328
Query: 287 QTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLK 108
+ S++ +E++Q + ++K+ ++LN + Q+ N +LK
Sbjct: 1329 ENDSIKKENKEMKQNL------------------IPKLQKENEKLNNEISQIQIENEKLK 1370
Query: 107 KDVKFGFAWANSMHDLNGQEQKLK 36
K ++ +N + L + + LK
Sbjct: 1371 KQIEEMKQISNEISQLKQENEDLK 1394
Score = 94.4 bits (233), Expect = 2e-16
Identities = 163/801 (20%), Positives = 342/801 (42%), Gaps = 91/801 (11%)
Frame = -1
Query: 2165 NIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTERE-----------------ELNR 2037
N+ + + EN++ L ND +E+ A Q +E EL +
Sbjct: 171 NLEIIIKELRAENDQLNDELMNDQAELEEKDAEIQELKEQNEGAYKMKYETATKTIELLQ 230
Query: 2036 QLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKA 1857
+ + +++ +AL + ++ +KQLQ+ N ++ KE + + K D
Sbjct: 231 KQISASQEISKENDALKSKLAEK---DKQLQNY-NDMNSLIKEQREQIEKLSKNIDDSSD 286
Query: 1856 LSEKEESTKNQLLIQTEQNKQLELEIEKLYGSL----QMKQMENTLLKDGNEKIYDLCKL 1689
+E E+ +N++ +Q ++L+ E + +G + ++KQ EN LK E + + K
Sbjct: 287 FAENEKKYQNEIQNLKKQIEELQ-ENDNAWGDIDDTDEIKQ-ENENLKKEIENLKNQNKE 344
Query: 1688 LATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKV---NSDAGAKVSGILEML 1518
+ +++ + + I+K+ + + L + E + +++K+ N + KV + E +
Sbjct: 345 IGNLQLQIE-KLKDIIKEKESDNESLLQELEKSENNFEIEKIKKENQNLQTKVKEMQETI 403
Query: 1517 LPMK---------DDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIR-- 1371
++ D++ +++ IN+L+ + + +Q +E+ ++ EI
Sbjct: 404 DELESNAWNDDGNDEIKQNLDKLKQEINNLKKENENLQKQVEENEENAWNDGNNDEIEEI 463
Query: 1370 AQEVLRLQAEVDAIQHI---------LIELKRKNQTLQDESQRNAKELWNAKARLNNVMS 1218
Q + +LQ E + ++ I + +LK++ L+ E++ + LWN +N
Sbjct: 464 KQNLEKLQKENENLKKINEEKSNDDEINKLKQEISELKKENEELQENLWNENENEDN-QE 522
Query: 1217 KNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNV------LSSEVEN---LKSE- 1068
+ NL+ +N LK + + QK + EE E+E+++ L SEV+N LK E
Sbjct: 523 EISNLKKENEKLKQNIK-ELQKQIETNEENLWNENENDLKQKVTELESEVKNSDKLKEEN 581
Query: 1067 ---LKESKDLEGYFLRLFEILL-----GQHVEVASLDIESCRFAEEKLMRILDEL----- 927
KE+++L+ L E + Q E +I + + E+L + +DEL
Sbjct: 582 NKLKKENEELKKEIDDLTENVWKDDEDNQETEKLKQEINNLKKENEELKKEMDELQESTW 641
Query: 926 -ICLRNENAKLK---NEALYEYHDYERKNVSGSR-AEAMSVLISKSLGNGRANQREFQNK 762
E+ +LK E +Y D E+ N + E + L +S + +++ +
Sbjct: 642 NESYTEESDELKQKLKELEQKYKDTEKSNEDLKKLLEQVDNLQKESEKINQDLEKQIEEN 701
Query: 761 EEDS--SGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXX 588
+E+S ++LK K T LE +V+ EK ++ E +E + + ++E +Q+ +
Sbjct: 702 QENSDVDENEILKQKVTELESEVK---EKEKLNEELKKENEDLKKEVENLQENAWNETEN 758
Query: 587 XXXXXXXXIRVRSLKK---ENTRLRSEMKGELTPS---RSFKHREGSFIK--------EI 450
L+K EN + +++K +L+ S +S K+ E +K +
Sbjct: 759 EEIKEKLEKENEILQKQVEENNKTLNDLKQKLSESENEKSVKNSENDKLKQKVTEIESDF 818
Query: 449 NIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQ 270
I +E + L Q +++ L +N N+ + KQ Q
Sbjct: 819 KISNEKSSNLQQKLDVLSQNLEKLEKEMKISSEKNQKLQKENSDLQNQFTSLQKQNSDNQ 878
Query: 269 NSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFG 90
+ L + + ++ NS EK++++L + + E L+++VK G
Sbjct: 879 LKITSLLKEKSELENQLNENSTQ--NLESNSSEKEIRDLKEKITKQNEKIKELEEEVKKG 936
Query: 89 F--AW-ANSMHDLNGQEQKLK 36
+ W A+S D +++++K
Sbjct: 937 YQDLWGADSDDDSKEKDEEIK 957
Score = 63.9 bits (154), Expect = 3e-07
Identities = 135/692 (19%), Positives = 265/692 (38%), Gaps = 43/692 (6%)
Frame = -1
Query: 2045 LNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASD 1866
L ++ +RD L + + +VD+ + +E+ Q LE+ K +S L SVS++ S
Sbjct: 16 LKQKTARIRDLEKMLSQMNAPSVDNSSKIEELEQQLEDSKALISA-LQESVSQKNAEISR 74
Query: 1865 LKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLL 1686
L +S+ +N LI + Q K E + E ++ + N L D +
Sbjct: 75 LSLISQSNARNQNSDLIASLQKKIAEQQQE-------IESLNNELWNDDPNE-------- 119
Query: 1685 ATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLP-M 1509
+ K E+Q + I K N + + K LE+++ +
Sbjct: 120 SEKDIEIQNLKSQIQKLTKNQPQVSPASNNAELDTLRSQLAEMTQKTKEFSNLEIIIKEL 179
Query: 1508 KDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAI 1329
+ + L +E++ + L +Q EQ + + E + + LQ ++ A
Sbjct: 180 RAENDQLNDELMNDQAELEEKDAEIQELKEQNEGAYKMKY---ETATKTIELLQKQISAS 236
Query: 1328 QHILIE-------LKRKNQTLQDESQRNA--KELWNAKARLNNVMSKNINLESQNRSLKA 1176
Q I E L K++ LQ+ + N+ KE +L+ + + + + +
Sbjct: 237 QEISKENDALKSKLAEKDKQLQNYNDMNSLIKEQREQIEKLSKNIDDSSDFAENEKKYQN 296
Query: 1175 ELHLQAQKAFQIQEERNV---------VESEHNVLSSEVENLKSELKESKDLEGYFLRLF 1023
E+ ++ ++QE N ++ E+ L E+ENLK++ KE +L+ +L
Sbjct: 297 EIQNLKKQIEELQENDNAWGDIDDTDEIKQENENLKKEIENLKNQNKEIGNLQLQIEKLK 356
Query: 1022 EILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSG 843
+I+ + + SL E E+ E I N+N + K + + E D N
Sbjct: 357 DIIKEKESDNESLLQE----LEKSENNFEIEKIKKENQNLQTKVKEMQETIDELESNA-- 410
Query: 842 SRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFET 663
N N QN ++ ++ LK + L+ QV++ E A +
Sbjct: 411 --------------WNDDGNDEIKQNLDKLKQEINNLKKENENLQKQVEENEENA-WNDG 455
Query: 662 KSREAQQMANKLEEMQ------QTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEM---- 513
+ E +++ LE++Q + +++ + LKKEN L+ +
Sbjct: 456 NNDEIEEIKQNLEKLQKENENLKKINEEKSNDDEINKLKQEISELKKENEELQENLWNEN 515
Query: 512 -----KGELTPSRSFKHREGSFIKEI---------NIGDEDDTPLIQXXXXXXXXXXXKI 375
+ E++ + + IKE+ N+ +E++ L Q K+
Sbjct: 516 ENEDNQEEISNLKKENEKLKQNIKELQKQIETNEENLWNENENDLKQ-----------KV 564
Query: 374 DTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWG 195
SE + D L ++N K K+ + L+ + +L + W
Sbjct: 565 TELESEVKNSDKLKEENNK-------LKKENEELKKEIDDLTE-------------NVWK 604
Query: 194 GIDMNSIEKQLKELNIHVMQLVEHNTRLKKDV 99
+ N ++LK+ + L + N LKK++
Sbjct: 605 DDEDNQETEKLKQ---EINNLKKENEELKKEM 633
>ref|XP_653447.1| Viral A-type inclusion protein repeat [Entamoeba histolytica
HM-1:IMSS] gi|56470397|gb|EAL48061.1| Viral A-type
inclusion protein repeat, putative [Entamoeba histolytica
HM-1:IMSS]
Length = 1813
Score = 119 bits (298), Expect = 6e-24
Identities = 164/840 (19%), Positives = 353/840 (42%), Gaps = 75/840 (8%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEE 2121
EV ++EK++ + N ++ + ++I + ++QK+N ++L+ +
Sbjct: 633 EVIDKLKDEKEN---ISNELNQIKNERDNISNEFNKTKEEIKQKENETIQLNEEKSVLLN 689
Query: 2120 QRSALQNDMQSVEQMHAVSQTERE----ELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK 1953
+ + ++ + Q +E AV Q E+E +LN ++ +++N +K ++ +
Sbjct: 690 ELNQIKEEKQKIEDEKAVIQQEKENEITKLNEDKTVIENELNQIKTEKQEIENELNQTKD 749
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEEST-------KNQLLIQTEQNKQ 1794
+ Q +E++K + EL+ KL +L +++E+ KN+ EQN Q
Sbjct: 750 EKQKIEDEKSKLITELSNGNDGISKLNEELTQTKQEKENVLNELNQIKNEFASFKEQNTQ 809
Query: 1793 LELEIEKLYGSLQ--MKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQE--GILKQDIN 1626
E E++ +Q ++Q N + K EK +L TK Q +QE I ++
Sbjct: 810 KENELKDENNKVQQELEQKNNEVSKLEEEKGNISNELSNTKQELEQKKQEIITITQEKEE 869
Query: 1625 IEDEL-ARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRN 1449
E+EL + K++ + + S+ +S + E L K + KEE+ + +
Sbjct: 870 KENELKEQVKKIEEEKSKLITELSNGSDGISKLNEELTQTKQE----KEEIQKALEEEKE 925
Query: 1448 DAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIEL---KRKNQTLQDE 1278
+ ++ L+++++ K EL E +E LQ E++ + I+ EL K++ + + +E
Sbjct: 926 KLERIETELKEIKEAKQELEEEKNKTIEEKTNLQQELNENKKIVEELTQTKQEKEEINNE 985
Query: 1277 SQRNAKELWNAKARLNNVMSKNINLESQN------------------RSLKAELHLQAQK 1152
+E + N ++++N ++ +N LK L +
Sbjct: 986 LNSIKEEKKRIEEEKNQIINENKEIKEENIKSIEEKTQEINSLTTSIEELKGRLEESKGE 1045
Query: 1151 AFQIQEERNVVESEHNVLSSEVENLKSELKES--------KDLEGYFLRLFEILLGQHVE 996
+I++ER+ V SE N + + E +K +++E+ K EG + L Q +
Sbjct: 1046 RIEIEKERDRVISELNDIKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMINSLNNQITQ 1105
Query: 995 V--------------------ASLDIESCR----FAEEKLMRILDELICLRNENAKLKNE 888
+ +++++E + ++ K +I +E C+ E K+ E
Sbjct: 1106 LNEKEKQMNEQVMALQTQLSQSNINLEEVKKDLIESQNKYTQINEEKDCVEQERNKINEE 1165
Query: 887 --ALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTR 714
+ E + +K ++ + + + ++ + +NK+E +S ++ LK + T
Sbjct: 1166 YKTVNEELEKNKKELNDLQTKYDNEILELN-----------KNKDELNSLINNLKEEKTN 1214
Query: 713 LEFQVQKLSEKAEMFETKSREAQQMANKL-EEMQQTLSDMXXXXXXXXXXXIRVRSLKKE 537
LE QV+K+ E+ T+ +KL EE+ QT + + +++E
Sbjct: 1215 LEEQVKKMEEEKSKLITELSNGSDGVSKLNEELTQTKQEKEEINNELNSIKEEKKRIEEE 1274
Query: 536 NTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSE 357
++ +E K + + +KEI E + L I TR E
Sbjct: 1275 KNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQL--------QNEINTIQTRMKE 1326
Query: 356 TQEID-TLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMN 180
+E + ++ DN K ++ F ++ ++LQ + ++++ D++
Sbjct: 1327 IEEKNQEIICDNNK---EIAKFKEEQENLQKELNQIKEEKSKLI------------TDLS 1371
Query: 179 SIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHD-LNGQEQKL-KVDEEVPILCH 6
+ L +LN + + + ++K+++ N + D L + Q+L KV EE L H
Sbjct: 1372 NGNDGLSKLNEEIETINKEKEGIRKELESLKEENNKIQDELEQKNQELSKVKEEKEKLIH 1431
Score = 118 bits (296), Expect = 1e-23
Identities = 151/743 (20%), Positives = 328/743 (44%), Gaps = 73/743 (9%)
Frame = -1
Query: 2258 ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQR-SALQNDMQSVE 2082
E+ E FN +++NE I ++ E+K+N + E K++E + + + L N +
Sbjct: 300 EVIEKFNTSKEENEKIMNELSQLKQEKEEKENELKEQVKKMEEEKSKLITELSNGSDGIS 359
Query: 2081 QMH-AVSQT--EREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSK 1911
+++ ++QT E+EE+N +L ++++ ++E + +++ ++++ + +E +K+ + K
Sbjct: 360 KLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLK 419
Query: 1910 ELALSVSREQKLASDLKALSE--KEESTKNQLLI---------QTEQNKQLELEIEKLYG 1764
E+ +L +++ + KE KNQ +I E+ + L+ E+ ++
Sbjct: 420 EIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKE 479
Query: 1763 SLQMKQME-NTLLKDGNEKIYDLCKLLATKSREVQGQQ--EGILKQDINIEDELARTKE- 1596
Q + E N L+ +K +L KL K + + E L Q + +++L KE
Sbjct: 480 EKQKTENEKNELVDVKTQKENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKES 539
Query: 1595 VGRSATDMKKVNSDAGAKVSGILEMLLPMKDD---VFSLKEEVLGNINSLR-------ND 1446
+ + +K NS +++ I E +++D V KE + +N ++ +
Sbjct: 540 IKQELDSIKADNSTKELEINKINEEKNQLQNDYDTVQQEKENIQKELNQIKIEKSQKEEE 599
Query: 1445 AQMVQVALEQMQDTKSELFAEAE------IRAQEVL-RLQAEVDAIQHILIELKRKNQTL 1287
++ +Q++D K++L + + EV+ +L+ E + I + L ++K + +
Sbjct: 600 LNKIKEEKQQVEDEKAKLITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNI 659
Query: 1286 QDESQRNAKEL---WNAKARLNNVMSKNINLESQNRSLKAELH-----LQAQKAFQI--- 1140
+E + +E+ N +LN S +N +Q + K ++ +Q +K +I
Sbjct: 660 SNEFNKTKEEIKQKENETIQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQEKENEITKL 719
Query: 1139 QEERNVVESEHNVLSSEVENLKSELKESKD----LEGYFLRLFEILLGQHVEVASLDIES 972
E++ V+E+E N + +E + +++EL ++KD +E +L L + ++ L+ E
Sbjct: 720 NEDKTVIENELNQIKTEKQEIENELNQTKDEKQKIEDEKSKLITELSNGNDGISKLNEEL 779
Query: 971 CRFAEEKLMRILDELICLRNENA-----------KLKNEALYEYHDYERKNVSGSRAEAM 825
+ +EK +L+EL ++NE A +LK+E + E+KN S+ E
Sbjct: 780 TQTKQEK-ENVLNELNQIKNEFASFKEQNTQKENELKDENNKVQQELEQKNNEVSKLEEE 838
Query: 824 SVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETK----- 660
IS L N Q Q K+E + + K L+ QV+K+ E+ T+
Sbjct: 839 KGNISNELSN--TKQELEQKKQEIITITQEKEEKENELKEQVKKIEEEKSKLITELSNGS 896
Query: 659 ------SREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELT 498
+ E Q + EE+Q+ L + ++ K+E +++ E T
Sbjct: 897 DGISKLNEELTQTKQEKEEIQKALEEEKEKLERIETELKEIKEAKQELEEEKNKTIEEKT 956
Query: 497 PSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRK 318
+ + ++E+ ++ + + + E + ++N K
Sbjct: 957 NLQQELNENKKIVEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEENIK 1016
Query: 317 YWNRVSHFTKQTQSLQNSVQELQ 249
+ T++ SL S++EL+
Sbjct: 1017 ---SIEEKTQEINSLTTSIEELK 1036
Score = 112 bits (281), Expect = 5e-22
Identities = 153/781 (19%), Positives = 341/781 (43%), Gaps = 21/781 (2%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNN----LLEQKDNIIVELSHKLQ 2133
E++++ E + + N L+ +N + ++E NN L E+K NI ELS+ Q
Sbjct: 792 ELNQIKNEFASFKEQNTQKENELKDENNKVQQELEQKNNEVSKLEEEKGNISNELSNTKQ 851
Query: 2132 ENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK 1953
E E+++ + Q E+ + EL Q+ + ++ + L LS D + + +
Sbjct: 852 ELEQKKQEIITITQEKEE-------KENELKEQVKKIEEEKSKLITELSNGSDGISKLNE 904
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKE---ESTKNQLLIQTEQNKQLEL- 1785
+L + +KE + K L + +++ ++LK + E + E KN+ I+ + N Q EL
Sbjct: 905 ELTQTKQEKEEIQKALEEEKEKLERIETELKEIKEAKQELEEEKNK-TIEEKTNLQQELN 963
Query: 1784 EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 1605
E +K+ L + E + + I + K + + ++ + + I +++I +E +
Sbjct: 964 ENKKIVEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEENIKSIEE--K 1021
Query: 1604 TKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVA 1425
T+E+ T ++ ++ G LE + ++ ++ V+ +N ++ + ++
Sbjct: 1022 TQEINSLTTSIE--------ELKGRLEESKGERIEIEKERDRVISELNDIKLQNEGMKKQ 1073
Query: 1424 LEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNA 1245
+E+ + +E+ E E+ ++++ + + +L K + + ++
Sbjct: 1074 VEEAHNRMTEMQKSFEGSENEM------INSLNNQITQLNEKEKQMNEQ----------V 1117
Query: 1244 KARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL 1065
A + NINLE +K +L K QI EE++ VE E N ++ E + + EL
Sbjct: 1118 MALQTQLSQSNINLE----EVKKDLIESQNKYTQINEEKDCVEQERNKINEEYKTVNEEL 1173
Query: 1064 KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEA 885
+++K L ++ E+ L+ + DEL L N N K +
Sbjct: 1174 EKNKK------ELNDLQTKYDNEILELN------------KNKDELNSLIN-NLKEEKTN 1214
Query: 884 LYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQ---REFQNKEEDSSGVDLLKNKCTR 714
L E + K + +++ ++ L + S G + N+ + Q KEE ++ ++ +K + R
Sbjct: 1215 LEE----QVKKMEEEKSKLITELSNGSDGVSKLNEELTQTKQEKEEINNELNSIKEEKKR 1270
Query: 713 LEFQV-QKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKE 537
+E + Q ++E E+ E K + ++ L+E+++ R++ ++++
Sbjct: 1271 IEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEK 1330
Query: 536 NTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLI---QXXXXXXXXXXXKIDTR 366
N + + E+ FK + + KE+N E+ + LI +I+T
Sbjct: 1331 NQEIICDNNKEIA---KFKEEQENLQKELNQIKEEKSKLITDLSNGNDGLSKLNEEIETI 1387
Query: 365 TSETQ----EIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKW 198
E + E+++L ++N K + + ++ ++ ++L
Sbjct: 1388 NKEKEGIRKELESLKEENNKIQDELEQKNQELSKVKEEKEKLIHDLTN------------ 1435
Query: 197 GGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDV-KFGFAWANSMHDLNGQEQKLK-VDEE 24
G +N + + L ++ +L E N +L+ ++ K ++L+ +++ LK V+EE
Sbjct: 1436 GNDGINQLNEDLNQIKNDKEELTEKNVQLQNEINKLKSENEELSNNLSFEKEGLKQVNEE 1495
Query: 23 V 21
V
Sbjct: 1496 V 1496
Score = 112 bits (280), Expect = 7e-22
Identities = 142/766 (18%), Positives = 314/766 (40%), Gaps = 40/766 (5%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLK---IEANNN-----LLEQKDNIIVEL 2148
KE+ + E+EK+ +LQ N ++ + ++I K I +NN E+++N L
Sbjct: 415 KELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQEN----L 470
Query: 2147 SHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDR 1968
+L + +E++ +N+ + + + E +L + + ++ ++ +L+ V+++
Sbjct: 471 QKELNQIKEEKQKTENEKNELVDVKTQKENELNKLKEEKEQIFNEKTTIENSLNQIVEEK 530
Query: 1967 AFMEKQLQDLENQKETV-----SKELALSVSREQK--LASDLKALSEKEESTKNQLLIQT 1809
+ ++ + ++ + +++ +KEL ++ E+K L +D + +++E+ + +L
Sbjct: 531 NKLTEEKESIKQELDSIKADNSTKELEINKINEEKNQLQNDYDTVQQEKENIQKELNQIK 590
Query: 1808 EQNKQLELEIEKLYGSLQMKQMENTLL-------KDGNEKIYDLCKLLATKSREVQGQQE 1650
+ Q E E+ K+ Q + E L DG K+ ++ L + + +
Sbjct: 591 IEKSQKEEELNKIKEEKQQVEDEKAKLITDIANGNDGLTKLNEVIDKLKDEKENISNELN 650
Query: 1649 GILKQDINIEDELARTK-EVGRSATDMKKVNSDAGA---KVSGILEMLLPMKDDVFSLKE 1482
I + NI +E +TK E+ + + ++N + +++ I E ++D+ +++
Sbjct: 651 QIKNERDNISNEFNKTKEEIKQKENETIQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQ 710
Query: 1481 EVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKR 1302
E I L D +++ L Q++ K E+ E E +++ D ++ EL
Sbjct: 711 EKENEITKLNEDKTVIENELNQIKTEKQEIENELNQTKDEKQKIE---DEKSKLITELSN 767
Query: 1301 KN---QTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEE 1131
N L +E + +E N LN + ++ + + QN + EL + K Q E+
Sbjct: 768 GNDGISKLNEELTQTKQEKENVLNELNQIKNEFASFKEQNTQKENELKDENNKVQQELEQ 827
Query: 1130 RN----VVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRF 963
+N +E E +S+E+ N K EL++ K
Sbjct: 828 KNNEVSKLEEEKGNISNELSNTKQELEQKK------------------------------ 857
Query: 962 AEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRAN 783
E+I + E + +NE + K + +++ ++ L + S G + N
Sbjct: 858 ---------QEIITITQEKEEKENELKEQV-----KKIEEEKSKLITELSNGSDGISKLN 903
Query: 782 Q---REFQNKEEDSSGVDLLKNKCTRLEFQVQKLSE-KAEMFETKSREAQQMAN---KLE 624
+ + Q KEE ++ K K R+E +++++ E K E+ E K++ ++ N +L
Sbjct: 904 EELTQTKQEKEEIQKALEEEKEKLERIETELKEIKEAKQELEEEKNKTIEEKTNLQQELN 963
Query: 623 EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINI 444
E ++ + ++ + S+K+E R+ E + ++ K IK I
Sbjct: 964 ENKKIVEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEN---IKSIEE 1020
Query: 443 GDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNS 264
++ L R +E D ++ + + KQ + N
Sbjct: 1021 KTQEINSLTTSIEELKGRLEESKGERIEIEKERDRVISELNDIKLQNEGMKKQVEEAHNR 1080
Query: 263 VQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVE 126
+ E+Q+ +NS+ Q+ +LN Q+ E
Sbjct: 1081 MTEMQKSFEGSENEM-----------INSLNNQITQLNEKEKQMNE 1115
Score = 107 bits (267), Expect = 2e-20
Identities = 110/598 (18%), Positives = 252/598 (42%), Gaps = 19/598 (3%)
Frame = -1
Query: 2240 NALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQ 2061
N L Q D K N + +KD +I + + +ENE+ M + Q+ +
Sbjct: 275 NELTQLKTDNDQKENELNQVRHEKDEVIEKFNTSKEENEK-------IMNELSQLKQEKE 327
Query: 2060 TEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQ 1881
+ EL Q+ + ++ + L LS D + + ++L + +KE ++ EL
Sbjct: 328 EKENELKEQVKKMEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEINNEL-------- 379
Query: 1880 KLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYD 1701
+ +K ++ E KNQ++ +NK+++ E EK+ + E K+GN ++ +
Sbjct: 380 ---NSIKEEKKRIEEEKNQII---NENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQN 433
Query: 1700 LCKLLATKSREVQGQQEGIL-----------KQDINIEDELARTKEVGRSATDMKKVNSD 1554
+ T+ +E++ + + I+ ++ N++ EL + KE + + K D
Sbjct: 434 EINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELVD 493
Query: 1553 AGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEI 1374
+ L L K+ +F+ K + ++N + + + E ++ + A+
Sbjct: 494 VKTQKENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIKADNST 553
Query: 1373 RAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQ 1194
+ E+ ++ E + +Q+ ++++ + +Q E + E + LN + + +E +
Sbjct: 554 KELEINKINEEKNQLQNDYDTVQQEKENIQKELNQIKIEKSQKEEELNKIKEEKQQVEDE 613
Query: 1193 NRSLKAE-------LHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYF 1035
L + L + ++++E+ + +E N + +E +N+ +E ++K+
Sbjct: 614 KAKLITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNISNEFNKTKE----- 668
Query: 1034 LRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERK 855
E+ + E+ + EEK + +L+EL ++ E K+++E + E
Sbjct: 669 ------------EIKQKENETIQLNEEKSV-LLNELNQIKEEKQKIEDEKAVIQQEKEN- 714
Query: 854 NVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAE 675
E + K++ NQ + + +E ++N+ + + + QK+ ++
Sbjct: 715 -------EITKLNEDKTVIENELNQIKTEKQE--------IENELNQTKDEKQKIEDEKS 759
Query: 674 MFETKSREAQQMANKL-EEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGE 504
T+ +KL EE+ QT + S K++NT+ +E+K E
Sbjct: 760 KLITELSNGNDGISKLNEELTQTKQEKENVLNELNQIKNEFASFKEQNTQKENELKDE 817
Score = 100 bits (249), Expect = 3e-18
Identities = 153/829 (18%), Positives = 326/829 (39%), Gaps = 69/829 (8%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
KE + EEEK TIE + N +N+ I ++ E+ +N + + + + E
Sbjct: 938 KEAKQELEEEKNKTIEEKTNLQQELNENKKIVEELTQTKQEKEEINNELNSIKEEKKRIE 997
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK--- 1953
E+++ + N+ + +++ + S EE +++ L + LK L + +R +EK
Sbjct: 998 EEKNQIINENKEIKEENIKS---IEEKTQEINSLTTSIEELKGRLEESKGERIEIEKERD 1054
Query: 1952 ----QLQDLENQKETVSKELALSVSREQKLASDLKALSEKE--ESTKNQLLIQTEQNKQL 1791
+L D++ Q E + K++ + +R ++ + SE E S NQ+ E+ KQ+
Sbjct: 1055 RVISELNDIKLQNEGMKKQVEEAHNRMTEMQKSFEG-SENEMINSLNNQITQLNEKEKQM 1113
Query: 1790 ELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCK-LLATKSREVQ-GQQEGILKQDINIED 1617
++ L T L N + ++ K L+ ++++ Q +++ ++Q+ N +
Sbjct: 1114 NEQVMAL----------QTQLSQSNINLEEVKKDLIESQNKYTQINEEKDCVEQERNKIN 1163
Query: 1616 ELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQM 1437
E K V KK +D K + L KD++ SL IN+L+ +
Sbjct: 1164 E--EYKTVNEELEKNKKELNDLQTKYDNEILELNKNKDELNSL-------INNLKEEKTN 1214
Query: 1436 VQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKE 1257
++ +++M++ KS+L E + V +L E+ + E+ + ++++E +R +E
Sbjct: 1215 LEEQVKKMEEEKSKLITELSNGSDGVSKLNEELTQTKQEKEEINNELNSIKEEKKRIEEE 1274
Query: 1256 LWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVES------------ 1113
+ + +E + + L E+ + + Q+Q E N +++
Sbjct: 1275 KNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEI 1334
Query: 1112 ------EHNVLSSEVENLKSELKESKDLEGYFLRLFE------ILLGQHVEVASLDIESC 969
E E ENL+ EL + K+ + + L + +E + + E
Sbjct: 1335 ICDNNKEIAKFKEEQENLQKELNQIKEEKSKLITDLSNGNDGLSKLNEEIETINKEKEGI 1394
Query: 968 RFAEEKLM----RILDELICLRNENAKLKNEALYEYHDYERKN------------VSGSR 837
R E L +I DEL E +K+K E HD N + +
Sbjct: 1395 RKELESLKEENNKIQDELEQKNQELSKVKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDK 1454
Query: 836 AE--AMSVLISKSLGNGRANQREFQNK--------EEDSSGVDLLKNKCTRLEFQVQKLS 687
E +V + + ++ E N ++ + V+ +K + L Q++K+
Sbjct: 1455 EELTEKNVQLQNEINKLKSENEELSNNLSFEKEGLKQVNEEVNAIKEERDELVKQIKKIE 1514
Query: 686 EKAEMFETK--------SREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENT 531
E+ E + + + Q+ N+ E++ Q +++ + K+ N
Sbjct: 1515 EEKRKVEEELNFNGSEVNEQIAQINNEKEQLNQECNELKQNLKELQSKIEEIEQEKESNE 1574
Query: 530 RLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQ 351
+ E EL + K + +KE I+ ++ ++ T+
Sbjct: 1575 IKKKEELQELQEEITEKDNDIKNLKE----------EIERIEKELQEKEEDMEQMSNNTE 1624
Query: 350 EIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIE 171
E++ L + + + K+ +S+ N +E ++ +MN +
Sbjct: 1625 ELEELKNKLTETQRLLEEEKKEKESISNEFEETKEQVLVELQRVNN--------EMNKMN 1676
Query: 170 KQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEE 24
+ +E +L EH +LK ++ + L + +LK + E
Sbjct: 1677 EIKQEDENEKEELQEHINKLKSQIERENEQLKEVSKLKWELSELKTENE 1725
Score = 99.0 bits (245), Expect = 8e-18
Identities = 128/746 (17%), Positives = 325/746 (43%), Gaps = 37/746 (4%)
Frame = -1
Query: 2165 NIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALS 1986
N +E +K +NE + + D Q + + E +++ +L ++ L + ++
Sbjct: 179 NAQIEEENKRLQNENEELKKKCDAQ--DSLLKTKMKSEMEAKKKVEILENEKKDLIDKMA 236
Query: 1985 MAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQL-LIQT 1809
D + + ++L ++N+KE+++ EL + ++ + ++L L + +N+L ++
Sbjct: 237 NENDGMSKLNEELTQIKNEKESINNELIQTKQEKESINNELTQLKTDNDQKENELNQVRH 296
Query: 1808 EQNKQLEL------EIEKLYGSL-QMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQE 1650
E+++ +E E EK+ L Q+KQ + + E++ + + + E+ +
Sbjct: 297 EKDEVIEKFNTSKEENEKIMNELSQLKQEKEEKENELKEQVKKMEEEKSKLITELSNGSD 356
Query: 1649 GILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLG 1470
GI K + +EL +TK+ + +++N++ L +K++ ++EE
Sbjct: 357 GISK----LNEELTQTKQ------EKEEINNE-----------LNSIKEEKKRIEEEK-- 393
Query: 1469 NINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQT 1290
N + N+ + ++ E++++ K EL E E + +LQ E++ IQ + E++ KNQ
Sbjct: 394 --NQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQE 451
Query: 1289 L--------------QDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQK 1152
+ Q+ Q+ ++ K + N ++ +++++Q + +L + ++
Sbjct: 452 IICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELVDVKTQKENELNKLKEEKEQ 511
Query: 1151 AFQ----IQEERNVVESEHNVLSSEVENLKSELKESK-DLEGYFLRLFEILLGQHVEVAS 987
F I+ N + E N L+ E E++K EL K D L + +I +
Sbjct: 512 IFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIKADNSTKELEINKI--NEEKNQLQ 569
Query: 986 LDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISK 807
D ++ + +E + + L+++ +++ K E L + + E++ V +A+ ++ + +
Sbjct: 570 NDYDTVQQEKENIQKELNQIKIEKSQ----KEEELNKIKE-EKQQVEDEKAKLITDIANG 624
Query: 806 SLGNGRANQ---REFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQ-- 642
+ G + N+ + KE S+ ++ +KN+ + + K E+ + E ++ + +
Sbjct: 625 NDGLTKLNEVIDKLKDEKENISNELNQIKNERDNISNEFNKTKEEIKQKENETIQLNEEK 684
Query: 641 -----MANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKH 477
N+++E +Q + D + L ++ T + +E+ T + ++
Sbjct: 685 SVLLNELNQIKEEKQKIED--EKAVIQQEKENEITKLNEDKTVIENELNQIKTEKQEIEN 742
Query: 476 REGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSH 297
E +++ + LI + T QE + ++++ + N +
Sbjct: 743 ELNQTKDEKQKIEDEKSKLITELSNGNDGISKLNEELTQTKQEKENVLNELNQIKNEFAS 802
Query: 296 FTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNT 117
F +Q +N +++ + N ++++L++ N V +L E
Sbjct: 803 FKEQNTQKENELKD----------------------ENNKVQQELEQKNNEVSKLEEEKG 840
Query: 116 RLKKDVKFGFAWANSMHDLNGQEQKL 39
+ ++ +N+ +L ++Q++
Sbjct: 841 NISNEL------SNTKQELEQKKQEI 860
Score = 97.1 bits (240), Expect = 3e-17
Identities = 96/443 (21%), Positives = 210/443 (47%), Gaps = 24/443 (5%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLK---IEANNN-----LLEQKDNIIVEL 2148
KE+ + E+EK+ +LQ N ++ + ++I K I +NN E+++N L
Sbjct: 1297 KELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQEN----L 1352
Query: 2147 SHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDR 1968
+L + +E++S L D+ + + E E +N++ +R ++ LKE + D+
Sbjct: 1353 QKELNQIKEEKSKLITDLSNGNDGLSKLNEEIETINKEKEGIRKELESLKEENNKIQDEL 1412
Query: 1967 AFMEKQLQDLENQKETVSKELALSVSREQKLASDLKAL-SEKEESTKNQLLIQTEQNKQL 1791
++L ++ +KE + +L +L DL + ++KEE T+ + +Q E NK L
Sbjct: 1413 EQKNQELSKVKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDKEELTEKNVQLQNEINK-L 1471
Query: 1790 ELEIEKLYGSLQMKQMENTLLKDGNEKIY-------DLCKLLATKSREVQGQQEGILKQD 1632
+ E E+L +L E LK NE++ +L K + E + +E +
Sbjct: 1472 KSENEELSNNL---SFEKEGLKQVNEEVNAIKEERDELVKQIKKIEEEKRKVEEELNFNG 1528
Query: 1631 INIEDELAR----TKEVGRSATDMKKVNSDAGAKVSGILEML----LPMKDDVFSLKEEV 1476
+ +++A+ +++ + ++K+ + +K+ I + + K+++ L+EE+
Sbjct: 1529 SEVNEQIAQINNEKEQLNQECNELKQNLKELQSKIEEIEQEKESNEIKKKEELQELQEEI 1588
Query: 1475 LGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKN 1296
N ++N + ++ +++Q+ K E + +E+ L+ ++ Q +L E K++
Sbjct: 1589 TEKDNDIKNLKEEIERIEKELQE-KEEDMEQMSNNTEELEELKNKLTETQRLLEEEKKEK 1647
Query: 1295 QTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVE 1116
+++ +E + +++ R+NN M+K ++ ++ + K EL K E N
Sbjct: 1648 ESISNEFEETKEQVLVELQRVNNEMNKMNEIKQEDENEKEELQEHINKLKSQIERENEQL 1707
Query: 1115 SEHNVLSSEVENLKSELKESKDL 1047
E + L E+ LK+E + K +
Sbjct: 1708 KEVSKLKWELSELKTENESMKQM 1730
Score = 73.9 bits (180), Expect = 3e-10
Identities = 76/367 (20%), Positives = 172/367 (46%), Gaps = 8/367 (2%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQEN---FNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQ 2133
KE+ L EE + EL++ + ++++ E + + N+ + Q + + ++ + +
Sbjct: 1396 KELESLKEENNKIQDELEQKNQELSKVKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDKE 1455
Query: 2132 ENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK 1953
E E+ LQN++ ++ +E EEL+ L ++ + + E ++ ++R + K
Sbjct: 1456 ELTEKNVQLQNEINKLK-------SENEELSNNLSFEKEGLKQVNEEVNAIKEERDELVK 1508
Query: 1952 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLL--IQTEQNKQLELEI 1779
Q++ +E +K V +EL + S + + + E+ N+L ++ Q+K E+E
Sbjct: 1509 QIKKIEEEKRKVEEELNFNGSEVNEQIAQINNEKEQLNQECNELKQNLKELQSKIEEIEQ 1568
Query: 1778 EKLYGSLQMKQMENTLLKDGNEKIYDLCKL---LATKSREVQGQQEGILKQDINIEDELA 1608
EK ++ K+ L ++ EK D+ L + +E+Q ++E + + N E+
Sbjct: 1569 EKESNEIKKKEELQELQEEITEKDNDIKNLKEEIERIEKELQEKEEDMEQMSNNTEE--- 1625
Query: 1607 RTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQV 1428
+E+ T+ +++ + + I K+ V + V +N + Q +
Sbjct: 1626 -LEELKNKLTETQRLLEEEKKEKESISNEFEETKEQVLVELQRVNNEMNKMNEIKQEDEN 1684
Query: 1427 ALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWN 1248
E++Q+ ++L ++ E R E L+ EV ++ L ELK +N++++ + + N
Sbjct: 1685 EKEELQEHINKLKSQIE-RENEQLK---EVSKLKWELSELKTENESMK-------QMIMN 1733
Query: 1247 AKARLNN 1227
K+ L+N
Sbjct: 1734 KKSLLDN 1740
>ref|XP_001319569.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121902355|gb|EAY07346.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 940
Score = 118 bits (296), Expect = 1e-23
Identities = 137/691 (19%), Positives = 292/691 (42%), Gaps = 43/691 (6%)
Frame = -1
Query: 2048 ELNRQLVLLRDDVNHLKEALSMAVDDRAF-----------MEKQLQDLENQKETVSKELA 1902
E+ +Q+ +N LKE L +++ ++KQ+ +++NQ E + KE
Sbjct: 3 EIKKQIEEKDKQINELKEELQKQTEEKETEINELMNQIEDLQKQIDEIKNQNENLQKEKE 62
Query: 1901 LSVSREQKLASDL--------KALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQ 1746
S++ K DL KAL E+ E KNQL +Q + L+ E E+ +L+ +
Sbjct: 63 NSLNEMNKQIDDLQKEKEETEKALIEENEDYKNQLSELKKQIEDLQNENEEKVENLKKEN 122
Query: 1745 ME-NTLLKDGNEKIYDLCKLLATKSREVQ------GQQEGILKQDINIEDELARTK---- 1599
E N +KD ++I L K ++ + Q QQ LKQ ++ E +L + K
Sbjct: 123 EEFNNEIKDLQDQIELLKKSMSESEDKDQKFVIELNQQIEKLKQKVSDEKDLIQVKDEEI 182
Query: 1598 -EVGRSATDM----KKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMV 1434
++ + TD+ K+N D I E+ + D+ S KE++ IN L+++ +
Sbjct: 183 IDLKQKNTDLSEQNNKLNEDKNELEKQIEELAQKLSDE--SEKEKLKQEINELKSEKENS 240
Query: 1433 QVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKEL 1254
+ + + ++ E E + R E+D + ++ K L +E+++ ++ L
Sbjct: 241 EKDFNKKLENLTQKVTELEDSISQKTR---EIDEAETAKEDISLKLDNLAEENEKLSQNL 297
Query: 1253 WNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQE----ERNVVESEHNVLSSEV 1086
+LN +++ L+ +N LK+E L + + QE E ++ E+ ++ ++
Sbjct: 298 SEIYEKLNEKVTETEKLQKENEDLKSENELLKKDSDSAQEELMKENENLKKENGEITEKI 357
Query: 1085 ENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNEN 906
E L+ E+ E + + E + Q+ E + + + +++ I +L + EN
Sbjct: 358 EELQKEIGERQKTVEDLKQKIEEINSQNAEESEKNQKEIDDLTQEIEEINQKLDEKQKEN 417
Query: 905 AKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKN 726
LK E E + + + N NQ + +N ++++ DL K
Sbjct: 418 DDLKKE-----------------KENLQKEVDEIKKNFEENQNQIENLQKEND--DLKKG 458
Query: 725 KCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSL 546
E + +++ E + FE K +E + + EEM Q L + ++
Sbjct: 459 MNQSSEEKQKEIEEIKKNFEEKQKEIDDLTQENEEMNQKLDE---KQKEIEEIKQKIEEN 515
Query: 545 KKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTR 366
+K+N L+ E++ + ++ + +N E+ I+ +++++
Sbjct: 516 QKQNVDLKKEVEDLTQEIEKLEEQKSQKEENVNSEQENLQKQIEELKNEKETISNELESK 575
Query: 365 TSETQEIDTLMDD----NRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKW 198
T +++ + + + N + + T++ + L N+V +LQ
Sbjct: 576 TKHNEKLVSSLQEFAKKNAELDITIERLTQEKEVLINNVNDLQNNVDAEIRDLK------ 629
Query: 197 GGIDMNSIEKQLKELNIHVMQLVEHNTRLKK 105
+ + ++++ LN + Q+++ N LK+
Sbjct: 630 --VKLQEKDEEIDGLNEQIEQIIKENNDLKQ 658
Score = 110 bits (275), Expect = 3e-21
Identities = 108/478 (22%), Positives = 225/478 (47%), Gaps = 24/478 (5%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
K +++ EE+++ E+++NF +++ +D+ + E N L++K I E+ K++EN+
Sbjct: 457 KGMNQSSEEKQKEIEEIKKNFEEKQKEIDDLTQENEEMNQKLDEKQKEIEEIKQKIEENQ 516
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQ 1944
+Q L+ +++ + Q E E+L Q ++VN +E L +KQ++
Sbjct: 517 KQNVDLKKEVEDLTQ-------EIEKLEEQKSQKEENVNSEQENL----------QKQIE 559
Query: 1943 DLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYG 1764
+L+N+KET+S EL +KL S L+ ++K N +L++ IE+L
Sbjct: 560 ELKNEKETISNELESKTKHNEKLVSSLQEFAKK--------------NAELDITIERLTQ 605
Query: 1763 SLQ-MKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGR 1587
+ + N L + + +I DL L K E+ G E I +Q I ++L + +E +
Sbjct: 606 EKEVLINNVNDLQNNVDAEIRDLKVKLQEKDEEIDGLNEQI-EQIIKENNDLKQKQEENQ 664
Query: 1586 SATDMK-KVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINS----LRNDAQMVQVAL 1422
+ K K N D +V + + + +++ +EE N+NS L+ + ++ +
Sbjct: 665 KENEQKQKENEDLKKEVDDLTQEIEKLEEQKSQKEEE---NVNSEQENLQKQIEELKKEV 721
Query: 1421 EQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQH---------------ILIELKRKNQTL 1287
EQ + +L E E +++ LQ +++ I+ + I + K + +
Sbjct: 722 EQYKKQNEDLIEENEEMDEKMKILQKQIEEIKETNEESSEQIYALKKDLEIAEQEKERIV 781
Query: 1286 QDESQRNAKELWNAKARLNNVMSKNINLESQNR--SLKAELHLQAQKAF-QIQEERNVVE 1116
+ E ++N KE+ K + + I+ E QN+ S+ E + +K +++++ N+ +
Sbjct: 782 KMEREQNMKEISQLKFEVEE--KRRISEEYQNKCQSIAEEFKQREKKVLAEVEKKFNMFK 839
Query: 1115 SEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMR 942
S + + S+++ + ++L K +E + +LG + D+ S EK R
Sbjct: 840 SAIDKIVSKLQIVDNKLNNIKAIEKTVIESLAPVLGIDSTEINFDVSSITPLVEKAKR 897
Score = 97.8 bits (242), Expect = 2e-17
Identities = 132/630 (20%), Positives = 281/630 (44%), Gaps = 61/630 (9%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKI----EANNNLLEQKDNIIVELSHKL 2136
++V+ L + Q T E+ E A EDI LK+ E N L + I +L+ K+
Sbjct: 253 QKVTELEDSISQKTREIDEAETA----KEDISLKLDNLAEENEKLSQNLSEIYEKLNEKV 308
Query: 2135 QENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFME 1956
E E+ + ++ E + S + +EEL ++ L+ + + E + + +
Sbjct: 309 TETEKLQKENEDLKSENELLKKDSDSAQEELMKENENLKKENGEITEKIEELQKEIGERQ 368
Query: 1955 KQLQDLENQKETVSKELALSVSREQK----LASDLKALSEK--EESTKNQLLIQTEQNKQ 1794
K ++DL+ + E ++ + A + QK L +++ +++K E+ +N L + ++N Q
Sbjct: 369 KTVEDLKQKIEEINSQNAEESEKNQKEIDDLTQEIEEINQKLDEKQKENDDLKKEKENLQ 428
Query: 1793 LELE-----IEKLYGSLQMKQMENTLLKDG--------NEKIYDLCKLLATKSREVQG-- 1659
E++ E+ ++ Q EN LK G ++I ++ K K +E+
Sbjct: 429 KEVDEIKKNFEENQNQIENLQKENDDLKKGMNQSSEEKQKEIEEIKKNFEEKQKEIDDLT 488
Query: 1658 QQEGILKQDIN-----IEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVF 1494
Q+ + Q ++ IE+ + +E + D+KK D ++ + E +++V
Sbjct: 489 QENEEMNQKLDEKQKEIEEIKQKIEENQKQNVDLKKEVEDLTQEIEKLEEQKSQKEENVN 548
Query: 1493 SLKEEVLGNINSLRNDAQMVQVALE---------------------QMQDTKSELFAEAE 1377
S +E + I L+N+ + + LE ++ T L E E
Sbjct: 549 SEQENLQKQIEELKNEKETISNELESKTKHNEKLVSSLQEFAKKNAELDITIERLTQEKE 608
Query: 1376 IRAQEVLRLQAEVDA-IQHILIELKRKNQT---LQDESQRNAKELWNAKARLNNVMSKNI 1209
+ V LQ VDA I+ + ++L+ K++ L ++ ++ KE + K + +N
Sbjct: 609 VLINNVNDLQNNVDAEIRDLKVKLQEKDEEIDGLNEQIEQIIKENNDLKQKQEENQKENE 668
Query: 1208 NLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLR 1029
+ +N LK E+ Q+ +++E+++ E E+ ++SE ENL+ +++E K + +
Sbjct: 669 QKQKENEDLKKEVDDLTQEIEKLEEQKSQKEEEN--VNSEQENLQKQIEELKKEVEQYKK 726
Query: 1028 LFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNV 849
E L+ ++ E+ ++ M+IL + I E K NE E +K++
Sbjct: 727 QNEDLIEENEEM------------DEKMKILQKQI----EEIKETNEESSEQIYALKKDL 770
Query: 848 SGSRAEAMSVL-ISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRL--EFQVQK---LS 687
+ E ++ + + +Q +F+ +E+ + +NKC + EF+ ++ L+
Sbjct: 771 EIAEQEKERIVKMEREQNMKEISQLKFEVEEKRRISEE-YQNKCQSIAEEFKQREKKVLA 829
Query: 686 EKAEMFETKSREAQQMANKLEEMQQTLSDM 597
E + F ++ +KL+ + L+++
Sbjct: 830 EVEKKFNMFKSAIDKIVSKLQIVDNKLNNI 859
>ref|XP_807004.1| hypothetical protein [Trypanosoma cruzi strain CL Brener]
gi|70870905|gb|EAN85153.1| hypothetical protein,
conserved [Trypanosoma cruzi]
Length = 1129
Score = 117 bits (294), Expect = 2e-23
Identities = 146/709 (20%), Positives = 315/709 (44%), Gaps = 24/709 (3%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
+E +RL + T +Q+ L+Q+ +++ N++L +Q N+ EL +E E
Sbjct: 385 EERARLEAKNTDKTKLIQD----LQQEKDNV---YSQNSDLAKQLKNLEEELHKLRKELE 437
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQ 1944
+Q++ + + +Q ++E++RQL +++V L++ + + QL+
Sbjct: 438 QQKTFAKKQEEYHKQQIEKKIKNQQEMSRQLQQSKEEVKQLQQQDKKRDKENHGYKTQLE 497
Query: 1943 DLENQKETV-SKELALSVSREQKLASDLKALSEKEESTKNQLLIQT-EQNKQLELEIEKL 1770
+E Q E + +K L S EQ KNQ +I+ E K L+L++E++
Sbjct: 498 KMEEQMEEINNKNKTLKKSIEQ----------------KNQEIIELYEHAKDLQLQLEEM 541
Query: 1769 YGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINI----EDELART 1602
+ ++ ++EN L+ +E + ++ ++ ++Q Q E + ++ + ED+
Sbjct: 542 HAEIEQLRVENEELRAEDEHKTRGLQEVSEQAEDLQRQLEELRAENEELRAEHEDKTRGL 601
Query: 1601 KEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVAL 1422
+EV A D+++ LE L +++ + E+ + + A+ +Q L
Sbjct: 602 QEVSEQAEDLQRQ-----------LEELRAENEELRAEHEDKTRGLQEVSEQAEDLQRQL 650
Query: 1421 EQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAK 1242
E+++ EL AE E + + + + + + +Q L EL+ +N+ L+ E + + L
Sbjct: 651 EELRAENEELRAEHEDKTRGLQEVSEQAEDLQRQLEELRAENEELRAEHEDKTRGLQEVS 710
Query: 1241 ARLNNVMSKNINLESQNRSLKAE-------LHLQAQKAFQIQEERNVVESEHNVLSSEVE 1083
+ ++ + L ++N L+AE L +++A +Q + + +E+ L +E E
Sbjct: 711 EQAEDLQRQLEELRAENEELRAEDENKTRGLQEVSEQAEDLQRQLEELRAENEELRAEHE 770
Query: 1082 NLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAE------EKLMRILDELIC 921
+ L+E + R E L ++ E+ + + R + E L R L+E
Sbjct: 771 DKTRGLQEVSEQAEDLQRQLEELRAENEELRAEHEDKTRGLQEVSEQAEDLQRQLEE--- 827
Query: 920 LRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSS-G 744
LR EN +L+ E +E K + + + L RA E + + ED + G
Sbjct: 828 LRAENEELRAE-------HEDKTRGLQEVSEQAEDLQRQLEELRAENEELRAEHEDKTRG 880
Query: 743 VDLLKNKCTRLEFQVQKL-SEKAEM---FETKSREAQQMANKLEEMQQTLSDMXXXXXXX 576
+ + + L+ Q+++L +E E+ E K+R Q+++ + E++Q+ L ++
Sbjct: 881 LQEVSEQAEDLQRQLEELRAENEELRAEHEDKTRGLQEVSEQAEDLQRQLEEL------- 933
Query: 575 XXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXX 396
+R+ ++ TR E+ + + + +E+ DE T +Q
Sbjct: 934 RAENEELRAEHEDKTRGLQEVSEQAEDLQRQLEELRAENEELRAEDEHKTRGLQEVSEQA 993
Query: 395 XXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQ 249
+++ +E +E+ +D + VS +Q + LQ ++EL+
Sbjct: 994 EDLQRQLEELRAENEELRGEHEDKTRGLQEVS---EQAEDLQRQLEELR 1039
>ref|XP_006612821.1| PREDICTED: sporulation-specific protein 15-like [Apis dorsata]
Length = 2025
Score = 117 bits (292), Expect = 3e-23
Identities = 158/757 (20%), Positives = 308/757 (40%), Gaps = 89/757 (11%)
Frame = -1
Query: 2258 ELQENFNALRQKNEDICLKIEA-------------------------------------- 2193
ELQ NF+ ++ +NE + ++A
Sbjct: 594 ELQRNFDTMKLENETLKEDVKALKDDLEESKREMKAVGDALKDKEELKDVEFRELQQNMQ 653
Query: 2192 ------------NNNLLEQKDNI---IVELSHKLQENEEQRSALQNDMQSVEQMHAVSQT 2058
NN+L ++ D++ EL HKL + +++ +++ + +
Sbjct: 654 NLKTENGELKKENNDLKKENDDLKTRASELEHKLDDVKKELDEVESQNADLRAKIDNLEK 713
Query: 2057 EREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETV--------SKELA 1902
E E+ +++ L+ +++ LK AL VD+ ++ + + L+ ++E + + A
Sbjct: 714 ELEKDKKEIEQLKSEISSLKNALDKCVDEMEKLKVENEKLKTEREKIETTWSDENTSLKA 773
Query: 1901 LSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKD 1722
+ EQ L + +K L +K S LL + + KQ E+E + + E +KD
Sbjct: 774 KNTELEQNLTTAVKEL-DKIRSENADLLSELNRLKQ---ELESGKKEIDQLKSEIGSMKD 829
Query: 1721 GNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTK----EVGRSATDMKKVNSD 1554
EK D + L T++++++ + EG+ + + +E+A K E+ + TD K +
Sbjct: 830 ALEKCVDEIEKLKTENKDLKSEVEGLESERDRLTNEVADLKPKISELQQKLTDASKKLDE 889
Query: 1553 AGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEI 1374
A + S + + +K ++ + +E I+ L+ + ++ L++ D +L E
Sbjct: 890 AKVEDSDLRAEVDRLKKELENAGKE----IDQLKTEMNSLKSGLDKCVDEMEKLKNENSE 945
Query: 1373 RAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQ 1194
+V L+ E D++ L +K +N L+DE + K+L K + +N LE++
Sbjct: 946 LKSQVHGLRGEGDSLASELTNMKGENSALKDEKDQLNKQLAENKTENERLKKQNDELETE 1005
Query: 1193 NRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEIL 1014
N +K EL + E N ++ E+N L E+E L+ +LK D R E+
Sbjct: 1006 NTKIKKELE-------SCKGENNNLKDENNKLKDELEKLRGQLKSLNDETNKLKR--ELE 1056
Query: 1013 LGQH-VEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSR 837
+H +++ + + EK EL LRNE +LK + E D +
Sbjct: 1057 EAEHKIQILEPQLSRVQSENEKSQ---SELAVLRNEANELKAKLDRETLDNVNMRNAMKI 1113
Query: 836 AEAMSVLISKSLGNGRA-------NQREFQNKEEDSSGVDL-LKNKCTRLEFQVQKLSEK 681
E ++K L N RA ++ + K D+ V L LK +C L+ + L K
Sbjct: 1114 LEDQMHDLNKKLDNCRAENDALKQENKDLKTKLSDTEQVVLNLKTECDNLKEDITDLQRK 1173
Query: 680 AEMFETK--SREAQQMANKLE-------------EMQQTLSDMXXXXXXXXXXXIRVRSL 546
E + K +EA+ K+E ++++ L D+ + L
Sbjct: 1174 IEQLKQKITDQEAEIDHWKVEHCKFELDNEKLKADLEKILKDLNECQVAKKVIESDLIKL 1233
Query: 545 KKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTR 366
K E L ++ +LT ++ + E + D+ D +
Sbjct: 1234 KNEKDDLNKKLT-DLT--SQLDQQKKTLEAEKSAKDKGDVQIASLN-----------SEL 1279
Query: 365 TSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQE 255
+ +E++ L DN KY + + KQ S +N +++
Sbjct: 1280 EALKKELEKLRADNSKYRSEIDDLGKQLVSAKNELKD 1316
Score = 115 bits (287), Expect = 1e-22
Identities = 165/799 (20%), Positives = 339/799 (42%), Gaps = 71/799 (8%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIE----ANNNLLEQKDNIIVELSHKLQENE--- 2124
E+ K EL+ + LR + + + ++ N+ L ++KD + +L+ ENE
Sbjct: 937 EKLKNENSELKSQVHGLRGEGDSLASELTNMKGENSALKDEKDQLNKQLAENKTENERLK 996
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQ 1944
+Q L+ + +++ + E L + L+D++ L+ L D+ ++++L+
Sbjct: 997 KQNDELETENTKIKKELESCKGENNNLKDENNKLKDELEKLRGQLKSLNDETNKLKRELE 1056
Query: 1943 DLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQN-------KQLEL 1785
+ E++ + + +L+ S +K S+L L + K +L +T N K LE
Sbjct: 1057 EAEHKIQILEPQLSRVQSENEKSQSELAVLRNEANELKAKLDRETLDNVNMRNAMKILED 1116
Query: 1784 EIEKLYGSLQMKQMENTLLKDGNE----KIYDLCKLLATKSREVQGQQEGILKQDINIED 1617
++ L L + EN LK N+ K+ D +++ E +E I IE
Sbjct: 1117 QMHDLNKKLDNCRAENDALKQENKDLKTKLSDTEQVVLNLKTECDNLKEDITDLQRKIEQ 1176
Query: 1616 ELARTK----EVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRN 1449
+ E+ + K D K+ LE +L ++ K+ + ++ L+N
Sbjct: 1177 LKQKITDQEAEIDHWKVEHCKFELD-NEKLKADLEKILKDLNECQVAKKVIESDLIKLKN 1235
Query: 1448 DAQMVQVAL----EQMQDTKSELFAEAEIRAQ---EVLRLQAEVDAIQHILIELKRKNQT 1290
+ + L Q+ K L AE + + ++ L +E++A++ L +L+ N
Sbjct: 1236 EKDDLNKKLTDLTSQLDQQKKTLEAEKSAKDKGDVQIASLNSELEALKKELEKLRADNSK 1295
Query: 1289 LQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESE 1110
+ E K+L +AK L + + + L++ N +L++EL + ++ +
Sbjct: 1296 YRSEIDDLGKQLVSAKNELKDCRDEVVVLKNANNALRSEL-----------DPLRSLKDD 1344
Query: 1109 HNVLSSEVENLKSE----LKESKDLEGYFLRLFEILLGQHVEVASL-------------- 984
+N L++E+++LKSE L++ + LE F +L GQ VE+ L
Sbjct: 1345 YNRLTTELDDLKSENTKLLQDKRSLEDEFGKLRGEGDGQRVEIDRLKTTLDAEKTAAEKL 1404
Query: 983 --DIESCRFAEEKLMRILDE----LICLRNENAKLK---NEALYEYHDYERKNVS-GSRA 834
D++SC+ +KL ++E L + EN +LK +E+ + D E K S ++
Sbjct: 1405 RSDLQSCKTENDKLQAQINEMKRNLDKMETENDRLKRELDESKKKLEDMEAKMKSLENQL 1464
Query: 833 EAMSVL---ISKSLGNGRANQREFQNKEEDSSGV-DLLKNKCTRLEFQVQKLSEKAEMFE 666
+SV + K L R + +N+ E + V D + + T L+ +++ L KAE+ +
Sbjct: 1465 SNLSVEKEELVKELYRTREDLNNLRNELEKQTAVKDTMAKESTNLKEELEAL--KAELNK 1522
Query: 665 TKSREAQQMANKLEEMQQTLS----DMXXXXXXXXXXXIRVRSLKKENTRLRSEMKG--- 507
T+ E ++ N+ +++ ++ + + +L + N L E+ G
Sbjct: 1523 TRD-ENDKLKNENDKLNAEIARLNKQLDALKDESANLKNEIENLNERNAELSKELAGAKD 1581
Query: 506 ---ELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTL 336
++ + RE +K ED + ++D + E+DTL
Sbjct: 1582 NLKDMETQLNNLKRENDDLKNKINSLEDKMQEVDDLKKKLEETKKELD---KPSLELDTL 1638
Query: 335 MDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKE 156
N+K + +++ ++ +L+N + +LQ D N+++ +L +
Sbjct: 1639 KSTNKKLEDDLNNARNESLNLKNDLDKLQN-------------------DYNNLQTELTD 1679
Query: 155 LNIHVMQLVEHNTRLKKDV 99
L + E L+KD+
Sbjct: 1680 LKMERDTFRERAAALEKDL 1698
Score = 105 bits (262), Expect = 9e-20
Identities = 114/571 (19%), Positives = 264/571 (46%), Gaps = 13/571 (2%)
Frame = -1
Query: 2300 EVSRL---YEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQE 2130
E+ RL + EK +L+ + + + +N+ + +I L++ + L +L E
Sbjct: 1386 EIDRLKTTLDAEKTAAEKLRSDLQSCKTENDKLQAQINEMKRNLDKMETENDRLKRELDE 1445
Query: 2129 NEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQ 1950
++++ ++ M+S+E + E+EEL ++L R+D+N+L+ L + M K+
Sbjct: 1446 SKKKLEDMEAKMKSLENQLSNLSVEKEELVKELYRTREDLNNLRNELEKQTAVKDTMAKE 1505
Query: 1949 LQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKL 1770
+L+ + E + EL + KL ++ L+ + QL +++ L+ EIE L
Sbjct: 1506 STNLKEELEALKAELNKTRDENDKLKNENDKLNAEIARLNKQLDALKDESANLKNEIENL 1565
Query: 1769 YGSLQMKQMENTLLKDGNEKIYDLCKLLA---TKSREVQGQQEGILKQDINIEDELARTK 1599
NE+ +L K LA ++++ Q + +++ ++++++ +
Sbjct: 1566 -----------------NERNAELSKELAGAKDNLKDMETQLNNLKRENDDLKNKINSLE 1608
Query: 1598 EVGRSATDMKKVNSDAGAKV-SGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVAL 1422
+ + D+KK + ++ LE+ D + S +++ ++N+ RN++ ++ L
Sbjct: 1609 DKMQEVDDLKKKLEETKKELDKPSLEL-----DTLKSTNKKLEDDLNNARNESLNLKNDL 1663
Query: 1421 EQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAK 1242
+++Q+ + L E E + A++ L+ +KR+N L+D++ + EL + +
Sbjct: 1664 DKLQNDYNNLQTELTDLKMERDTFRERAAALEKDLVRVKRENDELKDQNAKFKTELDDCQ 1723
Query: 1241 ARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKS--E 1068
N ++ + L+S+N L+ L + +++E+ N ++ ++ L ++ + +
Sbjct: 1724 EENNRLLKELEKLKSENVKLQDNLINAKSEGDRLKEDLNKLKKDYTDLRGDLTKAREDRD 1783
Query: 1067 LKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKN- 891
+++ KD+E + + L + ++ S D+ C+ EKL + +L L+ EN KLK
Sbjct: 1784 IRKEKDVE--LDKEIDELKTTNAKLKS-DLYDCQKENEKLRK---QLTKLKAENDKLKKA 1837
Query: 890 ---EALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKC 720
+ L +Y +Y + G+ + L + N E ++ + S + + NK
Sbjct: 1838 LGVQRLRDYINY--LDGKGTEPKMADKLEESEINPNTTNDIEIEDLLKMSQDLSININKA 1895
Query: 719 TRLEFQVQKLSEKAEMFETKSREAQQMANKL 627
E ++Q L++ + E + + N L
Sbjct: 1896 ---EQEIQNLAKLLKPVELGAFDPDGWLNSL 1923
Score = 100 bits (250), Expect = 2e-18
Identities = 139/677 (20%), Positives = 284/677 (41%), Gaps = 24/677 (3%)
Frame = -1
Query: 2207 LKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQ------SVEQMHAVSQTEREE 2046
+ IE N L + ++ L+ +L+E Q AL +++ S+E+ A+ + + ++
Sbjct: 246 IDIEDLMNKLNNCEEMVANLTKELEEKNNQIDALNKELEQMFILKSLEEQIAIMKQDLKK 305
Query: 2045 LNRQL-----VLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKEL-----ALS 1896
+ ++ L + ++N L A +R +E +L +L KE + EL L
Sbjct: 306 KDEKISDLLNTLRQSEINLLGLDGLKAKLER--LEPELYELRETKEEIMDELNMMRDTLK 363
Query: 1895 VSREQ--KLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKD 1722
+Q ++ D L E ++ N+L + E+ + L E+E L L+ ++++N L+
Sbjct: 364 ERNDQIIQILEDKAKLEEYYKNKVNELEARFEEQESLSEELENLRNELEKQRIKNKELEA 423
Query: 1721 GNEKIYDLCKLLATKSREVQ---GQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDA 1551
E + L LA +E++ G+ E + K+++N++DE+ EV R D
Sbjct: 424 CCEDMDVLENKLAELEKELEDNRGELERLQKENLNLKDEI----EVERMEND-------- 471
Query: 1550 GAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIR 1371
K+ LE + +D +LK + L + ND + ALE D +L + E
Sbjct: 472 --KLRDRLEESKKLMEDNENLKAQ-LEQLRGENNDLMGQKKALE---DLNKQLNEDNESM 525
Query: 1370 AQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQN 1191
+ + L+A +D + + L ++R+ L DE+Q + K L +++N NL+++
Sbjct: 526 KRTMGNLEARIDNLSNELSNVERERDALLDENQ-------SVKRELERTLTENENLKTEL 578
Query: 1190 RSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESK---DLEGYFLRLFE 1020
+L + ++Q + ++ E+ L +V+ LK +L+ESK G L+ E
Sbjct: 579 DKADEQLDKLKAEKNELQRNFDTMKLENETLKEDVKALKDDLEESKREMKAVGDALKDKE 638
Query: 1019 ILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGS 840
L ++++ + +L + ++ L+ EN LK A H +
Sbjct: 639 ELKDVEFRELQQNMQNLKTENGELKKENND---LKKENDDLKTRASELEHKLDDVKKELD 695
Query: 839 RAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETK 660
E+ + + + N + E+D ++ LK++ + L+ + K ++ E +
Sbjct: 696 EVESQNADLRAKIDNLE------KELEKDKKEIEQLKSEISSLKNALDKCVDEMEKLKV- 748
Query: 659 SREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFK 480
E +++ + E+++ T SD SLK +NT L + + +
Sbjct: 749 --ENEKLKTEREKIETTWSD-------------ENTSLKAKNTELEQNLTTAVKELDKIR 793
Query: 479 HREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVS 300
+ E+N ++ + D EI+ L +N+ + V
Sbjct: 794 SENADLLSELNRLKQELESGKKEIDQLKSEIGSMKDALEKCVDEIEKLKTENKDLKSEVE 853
Query: 299 HFTKQTQSLQNSVQELQ 249
+ L N V +L+
Sbjct: 854 GLESERDRLTNEVADLK 870
Score = 93.6 bits (231), Expect = 3e-16
Identities = 142/767 (18%), Positives = 303/767 (39%), Gaps = 40/767 (5%)
Frame = -1
Query: 2279 EEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQN 2100
E +Q+ + + +R +N D+ ++ N L ++ ++ E+ E + AL+
Sbjct: 777 ELEQNLTTAVKELDKIRSENADLLSEL---NRLKQELESGKKEIDQLKSEIGSMKDALEK 833
Query: 2099 DMQSVEQMHAVS----------QTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQ 1950
+ +E++ + ++ER+ L ++ L+ ++ L++ L+ A + +
Sbjct: 834 CVDEIEKLKTENKDLKSEVEGLESERDRLTNEVADLKPKISELQQKLTDASKKLDEAKVE 893
Query: 1949 LQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKL 1770
DL + + + KEL + +L +++ +L + +++ +N +L+ ++ L
Sbjct: 894 DSDLRAEVDRLKKELENAGKEIDQLKTEMNSLKSGLDKCVDEMEKLKNENSELKSQVHGL 953
Query: 1769 YGS-------LQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDEL 1611
G L + EN+ LKD +++ T++ ++ Q + + ++ I+ EL
Sbjct: 954 RGEGDSLASELTNMKGENSALKDEKDQLNKQLAENKTENERLKKQNDELETENTKIKKEL 1013
Query: 1610 ARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQ 1431
K + D D K+ G L+ L D+ LK E + + Q+++
Sbjct: 1014 ESCKGENNNLKDENNKLKDELEKLRGQLKSL---NDETNKLKRE----LEEAEHKIQILE 1066
Query: 1430 VALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNA---- 1263
L ++Q + +E + E L+A++D +TL + + RNA
Sbjct: 1067 PQLSRVQSENEKSQSELAVLRNEANELKAKLD------------RETLDNVNMRNAMKIL 1114
Query: 1262 -KELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEV 1086
++ + +L+N ++N L+ +N+ LK +L Q ++ E + ++ + L ++
Sbjct: 1115 EDQMHDLNKKLDNCRAENDALKQENKDLKTKLSDTEQVVLNLKTECDNLKEDITDLQRKI 1174
Query: 1085 ENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFA--EEKLMRILDELICLRN 912
E LK ++ + Q E+ +E C+F EKL L++++ N
Sbjct: 1175 EQLKQKITD-----------------QEAEIDHWKVEHCKFELDNEKLKADLEKILKDLN 1217
Query: 911 ENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLL 732
E K + E + KN + ++ L S+ + + E K++ + L
Sbjct: 1218 ECQVAKK--VIESDLIKLKNEKDDLNKKLTDLTSQLDQQKKTLEAEKSAKDKGDVQIASL 1275
Query: 731 KNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVR 552
++ L+ +++KL + + E + +L + L D V
Sbjct: 1276 NSELEALKKELEKLRADNSKYRS---EIDDLGKQLVSAKNELKD----------CRDEVV 1322
Query: 551 SLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKID 372
LK N LRS EL P RS K E++ ++T L+Q
Sbjct: 1323 VLKNANNALRS----ELDPLRSLKDDYNRLTTELDDLKSENTKLLQDKRSLEDEFGKLRG 1378
Query: 371 TRTSETQEID---TLMDDNR----KYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXX 213
+ EID T +D + K + + + LQ + E+++
Sbjct: 1379 EGDGQRVEIDRLKTTLDAEKTAAEKLRSDLQSCKTENDKLQAQINEMKRNLDKMETENDR 1438
Query: 212 XXXKWG---------GIDMNSIEKQLKELNIHVMQLVEHNTRLKKDV 99
+ M S+E QL L++ +LV+ R ++D+
Sbjct: 1439 LKRELDESKKKLEDMEAKMKSLENQLSNLSVEKEELVKELYRTREDL 1485
Score = 91.3 bits (225), Expect = 2e-15
Identities = 160/845 (18%), Positives = 333/845 (39%), Gaps = 81/845 (9%)
Frame = -1
Query: 2303 KEVSRLYEE---EKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQ 2133
KE+ +L E K + + L+ +N+D+ ++E + ++ N + +L K+
Sbjct: 815 KEIDQLKSEIGSMKDALEKCVDEIEKLKTENKDLKSEVEGLESERDRLTNEVADLKPKIS 874
Query: 2132 ENEEQRSALQN--DMQSVEQMHAVSQTER-----EELNRQLVLLRDDVNHLKEALSMAVD 1974
E +++ + D VE ++ +R E +++ L+ ++N LK L VD
Sbjct: 875 ELQQKLTDASKKLDEAKVEDSDLRAEVDRLKKELENAGKEIDQLKTEMNSLKSGLDKCVD 934
Query: 1973 D-------RAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEK--EESTKNQL 1821
+ + ++ Q+ L + ++++ EL L + L+++ E T+N+
Sbjct: 935 EMEKLKNENSELKSQVHGLRGEGDSLASELTNMKGENSALKDEKDQLNKQLAENKTENER 994
Query: 1820 LIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGIL 1641
L +QN +LE E K+ L+ + EN LKD N K+ D + +++GQ + +
Sbjct: 995 L--KKQNDELETENTKIKKELESCKGENNNLKDENNKLKD-------ELEKLRGQLKSLN 1045
Query: 1640 KQDINIEDELARTK-EVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNI 1464
+ ++ EL + ++ + +V S+ S + + + L E L N+
Sbjct: 1046 DETNKLKRELEEAEHKIQILEPQLSRVQSENEKSQSELAVLRNEANELKAKLDRETLDNV 1105
Query: 1463 NSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQ 1284
N +RN ++++ + + AE + QE L+ ++ + +++ LK + L+
Sbjct: 1106 N-MRNAMKILEDQMHDLNKKLDNCRAENDALKQENKDLKTKLSDTEQVVLNLKTECDNLK 1164
Query: 1283 D---ESQRNAKEL----WNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERN 1125
+ + QR ++L + +A +++ ++ E N LKA+L + + Q +
Sbjct: 1165 EDITDLQRKIEQLKQKITDQEAEIDHWKVEHCKFELDNEKLKADLEKILKDLNECQVAKK 1224
Query: 1124 VVESEHNVLSSEVENLKSEL--------KESKDLEG----------YFLRLFEILLGQHV 999
V+ES+ L +E ++L +L ++ K LE L L
Sbjct: 1225 VIESDLIKLKNEKDDLNKKLTDLTSQLDQQKKTLEAEKSAKDKGDVQIASLNSELEALKK 1284
Query: 998 EVASLDIESCRF-------------AEEKLMRILDELICLRNENAKLKNE-----ALYEY 873
E+ L ++ ++ A+ +L DE++ L+N N L++E +L +
Sbjct: 1285 ELEKLRADNSKYRSEIDDLGKQLVSAKNELKDCRDEVVVLKNANNALRSELDPLRSLKD- 1343
Query: 872 HDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSG----VDLLKNKCTRLEF 705
DY R + + + +K L + R+ + EF + G +D LK +
Sbjct: 1344 -DYNRLT---TELDDLKSENTKLLQDKRSLEDEFGKLRGEGDGQRVEIDRLKTTLDAEKT 1399
Query: 704 QVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRL 525
+KL + +T++ + Q N EM++ L M + KK+ +
Sbjct: 1400 AAEKLRSDLQSCKTENDKLQAQIN---EMKRNLDKM---ETENDRLKRELDESKKKLEDM 1453
Query: 524 RSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEI 345
++MK + + +KE+ ED L T+ +E+
Sbjct: 1454 EAKMKSLENQLSNLSVEKEELVKELYRTREDLNNLRNELEKQTAVKDTMAKESTNLKEEL 1513
Query: 344 --------------DTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXX 207
D L ++N K ++ KQ +L++ L+
Sbjct: 1514 EALKAELNKTRDENDKLKNENDKLNAEIARLNKQLDALKDESANLKNEIENLNERNAELS 1573
Query: 206 XKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDE 27
+ G N LK++ + L N LK + + DL + ++ K +
Sbjct: 1574 KELAGAKDN-----LKDMETQLNNLKRENDDLKNKINSLEDKMQEVDDLKKKLEETKKEL 1628
Query: 26 EVPIL 12
+ P L
Sbjct: 1629 DKPSL 1633
Score = 90.1 bits (222), Expect = 4e-15
Identities = 138/647 (21%), Positives = 279/647 (43%), Gaps = 49/647 (7%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQ----ENFNALRQKN--EDICLKIEANN--------NLLEQKD 2166
+E +L E+ + +L+ EN + + QK ED+ ++ +N NL + D
Sbjct: 478 EESKKLMEDNENLKAQLEQLRGENNDLMGQKKALEDLNKQLNEDNESMKRTMGNLEARID 537
Query: 2165 NIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALS 1986
N+ ELS+ E +R AL ++ QSV++ + TE E L +L
Sbjct: 538 NLSNELSNV----ERERDALLDENQSVKRELERTLTENENLKTEL--------------- 578
Query: 1985 MAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTE 1806
D+A ++QL L+ +K + + + L D+KAL + E +K ++ +
Sbjct: 579 ----DKA--DEQLDKLKAEKNELQRNFDTMKLENETLKEDVKALKDDLEESKREMKAVGD 632
Query: 1805 QNKQLE----LEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILK 1638
K E +E +L ++Q + EN LK N + L T++ E++ + + + K
Sbjct: 633 ALKDKEELKDVEFRELQQNMQNLKTENGELKKENNDLKKENDDLKTRASELEHKLDDVKK 692
Query: 1637 QDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINS 1458
+ +E + N+D AK+ + + L K ++ LK E+ N+
Sbjct: 693 ELDEVESQ-----------------NADLRAKIDNLEKELEKDKKEIEQLKSEISSLKNA 735
Query: 1457 LR---NDAQMVQVALEQMQ-----------DTKSELFAEAEIRAQEVLRLQAEVDAIQ-- 1326
L ++ + ++V E+++ D + L A+ Q + E+D I+
Sbjct: 736 LDKCVDEMEKLKVENEKLKTEREKIETTWSDENTSLKAKNTELEQNLTTAVKELDKIRSE 795
Query: 1325 --HILIELKRKNQTLQD---ESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQ 1161
+L EL R Q L+ E + E+ + K L + + L+++N+ LK+E+
Sbjct: 796 NADLLSELNRLKQELESGKKEIDQLKSEIGSMKDALEKCVDEIEKLKTENKDLKSEVEGL 855
Query: 1160 AQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLD 981
+ ++ E ++ + + L ++ + +L E+K +E LR L + +E A +
Sbjct: 856 ESERDRLTNEVADLKPKISELQQKLTDASKKLDEAK-VEDSDLRAEVDRLKKELENAGKE 914
Query: 980 IESCRFAEEKLM----RILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAE----AM 825
I+ + L + +DE+ L+NEN++LK++ V G R E A
Sbjct: 915 IDQLKTEMNSLKSGLDKCVDEMEKLKNENSELKSQ------------VHGLRGEGDSLAS 962
Query: 824 SVLISKSLGNGRANQREFQNKE--EDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSRE 651
+ K + ++++ NK+ E+ + + LK + LE + K+ ++ E + ++
Sbjct: 963 ELTNMKGENSALKDEKDQLNKQLAENKTENERLKKQNDELETENTKIKKELESCKGENNN 1022
Query: 650 AQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK 510
+ NKL++ + L +++SL E +L+ E++
Sbjct: 1023 LKDENNKLKDELEKL-------------RGQLKSLNDETNKLKRELE 1056
>ref|XP_001739846.1| intracellular protein transport protein USO1 [Entamoeba dispar
SAW760] gi|165896309|gb|EDR23762.1| intracellular protein
transport protein USO1, putative [Entamoeba dispar
SAW760]
Length = 1080
Score = 117 bits (292), Expect = 3e-23
Identities = 128/588 (21%), Positives = 272/588 (46%), Gaps = 31/588 (5%)
Frame = -1
Query: 2282 EEEKQHTIELQENF--------------NALRQKNEDICLKIEAN----NNLLEQKDNII 2157
EE K+ IE Q + N + ++ + I ++E N N+L ++DN I
Sbjct: 556 EEVKKDLIESQNKYTQVIEEKDGIEHERNKINEEYKTINEELEKNKKELNDLQIKQDNKI 615
Query: 2156 VELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAV 1977
+EL++ + + +E+R+ + ++ VE+ E+ +L +L D ++ L E L
Sbjct: 616 IELNNIINDLKEERTNFEEQVKKVEE-------EKTKLITELSNGNDGISKLNEELMQ-- 666
Query: 1976 DDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQ-- 1803
++K+ +++ N+ V +E ++K +++K EK E KN+L+ + E+
Sbjct: 667 -----IKKEKEEISNELNAVKEEKKQIEEEKEKEKTEIKEEKEKIEEEKNELIKEIEKEK 721
Query: 1802 --NKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDI 1629
K+L++EI K+ + QMK++E N+K +++ ++E+ E + ++
Sbjct: 722 EGKKELQIEINKI--NTQMKEIEE------NKK-----QIIFDNNKEI----ERLKEESE 764
Query: 1628 NIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRN 1449
NI+ EL + KE + K+ SD + G+ + L EE I ++
Sbjct: 765 NIQKELNQIKE------EKSKLMSDLSSGSDGLSK-----------LNEE----IETINK 803
Query: 1448 DAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIE----LKRKNQTLQD 1281
+ + +Q Q+++ +++ E E + QE+++L+ E + + L + + N+ L +
Sbjct: 804 EKEGIQNEFNQLKEENNKIQEELEQKNQELIKLKEEKEKLSLDLTNGNDGINQLNENL-N 862
Query: 1280 ESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNV 1101
+ + + +EL +L N ++K L+S+N L + ++ + Q+ EE N ++ E +
Sbjct: 863 QIKNDKEELTEKNIQLQNEINK---LKSENEELTNNISIEKEGLKQVNEEVNAIKEERDE 919
Query: 1100 LSSEVENLKSE---LKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDE 930
L ++ N++ E ++E +L G L I + E S + + + ++L ++E
Sbjct: 920 LVKQIRNIEEEKRKVEEELNLNGSELNERIIQISNEKEEVSQECNELKNSLKELQNKIEE 979
Query: 929 LICLRNENAKLKNEALYEYHD--YERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEE 756
+ + N K E + E + ER N + E + + Q+E Q KEE
Sbjct: 980 IEQEKEGNEISKKEQIEELQEEINERDNDIKNLKEEIERI-----------QKEVQEKEE 1028
Query: 755 DSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQ 612
D + + +E +L E + E + +E + ++N+ EE ++
Sbjct: 1029 DKEQISTTE----EVEELKNELIETQRLLEEERKEKESISNEFEETKE 1072
Score = 99.8 bits (247), Expect = 5e-18
Identities = 136/799 (17%), Positives = 335/799 (41%), Gaps = 54/799 (6%)
Frame = -1
Query: 2258 ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQ 2079
E+Q+ N + Q +E+ + + + E+K I E QE E + + L D VE
Sbjct: 93 EIQQKENEITQLHEEKSGLVNELSRIKEEKQKIEDEKIFIQQEKENEITKLNEDKIGVEN 152
Query: 2078 MHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELAL 1899
+TE++E+ +L ++++ ++E S + + + + L + + KE +
Sbjct: 153 ELNQIKTEKQEIENELNQIKEEKQKIEEEKSNLITELSNGNDGISKLNEELMQIKKEKEI 212
Query: 1898 SVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQME----NTL 1731
++ ++ ++ + E+ +N L ++N +++ E+E+ + + E
Sbjct: 213 TLDELNQIKNEFTSFKEQNIQKENDL---KDENNKIQQELEQKNNEISKLEEEKGNITNE 269
Query: 1730 LKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDA 1551
L + +++ + + + T + E + ++ + +Q +E+E ++ T++ N D
Sbjct: 270 LSNTKQELEEKKEEITTITHEKEERENELKEQVKKVEEEKSKL------ITELSNGN-DG 322
Query: 1550 GAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIR 1371
+K++G L + K+++ EE + + + ++ A +Q+++ K + E
Sbjct: 323 ISKLNGELTQIKKEKEEIKKELEEEKEKLERKEEELKEIKEAKQQLEEEKIKSIEEKTTL 382
Query: 1370 AQ----------EVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVM 1221
Q E+ ++ E + + + L +K + +++E + E N + + N+
Sbjct: 383 QQELEEKNKLVEEINEIKKEKEDVTNELSAVKEEKNKIEEEKNKITNE--NKEIKEENIK 440
Query: 1220 S-----KNIN-LESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKE 1059
S + IN L + LK L + + ++++ER+ SE N + + E LK +++E
Sbjct: 441 SIEEKTQEINSLTTSIEELKNYLEVSKGERIEVEKERDRATSELNDIKLQNEGLKKQVEE 500
Query: 1058 SKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENA-------K 900
+++ + FE G E+ S EK ++ ++++ L+ + + +
Sbjct: 501 TQNRMAEMQKSFE---GSENEMISSLNNQITQLNEKEKQMNEQVMALQTQLSQSNISLEE 557
Query: 899 LKNEALYEYHDY-----ERKNVSGSRAEAMS--VLISKSLGNGRANQREFQNKEED---- 753
+K + + + Y E+ + R + I++ L + + Q K+++
Sbjct: 558 VKKDLIESQNKYTQVIEEKDGIEHERNKINEEYKTINEELEKNKKELNDLQIKQDNKIIE 617
Query: 752 -SSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKL-EEMQQTLSDMXXXXXX 579
++ ++ LK + T E QV+K+ E+ T+ +KL EE+ Q +
Sbjct: 618 LNNIINDLKEERTNFEEQVKKVEEEKTKLITELSNGNDGISKLNEELMQIKKEKEEISNE 677
Query: 578 XXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXX 399
+ +++E + ++E+K E + + IKEI +++ +Q
Sbjct: 678 LNAVKEEKKQIEEEKEKEKTEIKEE---KEKIEEEKNELIKEIE-KEKEGKKELQIEINK 733
Query: 398 XXXXXXKIDTRTSE-----TQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXX 234
+I+ + +EI+ L +++ ++ ++ L + +
Sbjct: 734 INTQMKEIEENKKQIIFDNNKEIERLKEESENIQKELNQIKEEKSKLMSDLSSGSDGLSK 793
Query: 233 XXXXXXXXXXKWGGI---------DMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAW 81
+ GI + N I+++L++ N +++L E +L D+ G
Sbjct: 794 LNEEIETINKEKEGIQNEFNQLKEENNKIQEELEQKNQELIKLKEEKEKLSLDLTNG--- 850
Query: 80 ANSMHDLNGQEQKLKVDEE 24
+ ++ LN ++K D+E
Sbjct: 851 NDGINQLNENLNQIKNDKE 869
Score = 94.4 bits (233), Expect = 2e-16
Identities = 144/781 (18%), Positives = 335/781 (42%), Gaps = 51/781 (6%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
+E++++ EE++Q E + + N+ + E + L ++K+NI S++L + +
Sbjct: 22 EELNKIKEEKQQVEDEKAKLITDIANGNDGLTKLNEVIDKLKDEKENI----SNELNQIK 77
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQ 1944
+R + N+ ++ + E +L+ + L ++++ +KE D++ F++ Q
Sbjct: 78 NERDNITNEFNKTKEEIQQKENEITQLHEEKSGLVNELSRIKEEKQKIEDEKIFIQ---Q 134
Query: 1943 DLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYG 1764
+ EN+ ++++ + E +L + +K ++ E+ NQ+ E+ +++E E L
Sbjct: 135 EKENEITKLNED---KIGVENEL-NQIKTEKQEIENELNQI---KEEKQKIEEEKSNLIT 187
Query: 1763 SLQ-----MKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTK 1599
L + ++ L++ EK L +L K+ +++ I K++ ++ +
Sbjct: 188 ELSNGNDGISKLNEELMQIKKEKEITLDELNQIKNEFTSFKEQNIQKENDLKDENNKIQQ 247
Query: 1598 EVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALE 1419
E+ + ++ K+ + G I L K ++ KEE+ + ++ ++
Sbjct: 248 ELEQKNNEISKLEEEKG----NITNELSNTKQELEEKKEEITTITHEKEERENELKEQVK 303
Query: 1418 QMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQR---NAKELWN 1248
++++ KS+L E + +L E+ I+ E+K++ + +++ +R KE+
Sbjct: 304 KVEEEKSKLITELSNGNDGISKLNGELTQIKKEKEEIKKELEEEKEKLERKEEELKEIKE 363
Query: 1247 AKARLNNVMSKNI--------NLESQNR------SLKAELHLQAQKAFQIQEERNVVESE 1110
AK +L K+I LE +N+ +K E + ++EE+N +E E
Sbjct: 364 AKQQLEEEKIKSIEEKTTLQQELEEKNKLVEEINEIKKEKEDVTNELSAVKEEKNKIEEE 423
Query: 1109 HNVLSSE-----VENLKSELKESKDLEGYFLRL------FEILLGQHVEVASLDIESCRF 963
N +++E EN+KS ++++++ + E+ G+ +EV
Sbjct: 424 KNKITNENKEIKEENIKSIEEKTQEINSLTTSIEELKNYLEVSKGERIEV---------- 473
Query: 962 AEEKLMRILDEL--ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGR 789
E++ R EL I L+NE K + E +K+ GS E +S L ++ +
Sbjct: 474 -EKERDRATSELNDIKLQNEGLKKQVEETQNRMAEMQKSFEGSENEMISSLNNQIT---Q 529
Query: 788 ANQREFQNKEE--------DSSGVDLLKNKCTRLEFQ---VQKLSEKAEMFETKSR---E 651
N++E Q E+ S + L + K +E Q Q + EK + +++ E
Sbjct: 530 LNEKEKQMNEQVMALQTQLSQSNISLEEVKKDLIESQNKYTQVIEEKDGIEHERNKINEE 589
Query: 650 AQQMANKLEEMQQTLSDMXXXXXXXXXXXIR-VRSLKKENTRLRSEMKGELTPSRSFKHR 474
+ + +LE+ ++ L+D+ + LK+E T ++K +
Sbjct: 590 YKTINEELEKNKKELNDLQIKQDNKIIELNNIINDLKEERTNFEEQVK-------KVEEE 642
Query: 473 EGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHF 294
+ I E++ G++ + L + + + +E + ++ K +
Sbjct: 643 KTKLITELSNGNDGISKLNEELMQIKKEKEEISNELNAVKEEKKQIEEEKEKEKTEIKEE 702
Query: 293 TKQTQSLQNS-VQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNT 117
++ + +N ++E+++ I++N I Q+KE+ + Q++ N
Sbjct: 703 KEKIEEEKNELIKEIEKEKEGKKELQ---------IEINKINTQMKEIEENKKQIIFDNN 753
Query: 116 R 114
+
Sbjct: 754 K 754
Score = 86.3 bits (212), Expect = 5e-14
Identities = 92/414 (22%), Positives = 192/414 (46%), Gaps = 1/414 (0%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
KE+ + E +K+ IE+ + +++ E+ I NN +E+ + +L + +
Sbjct: 715 KEIEKEKEGKKELQIEINKINTQMKEIEENKKQIIFDNNKEIERLKEESENIQKELNQIK 774
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQ 1944
E++S L +D+ S + E E +N++ ++++ N LKE + ++ ++L
Sbjct: 775 EEKSKLMSDLSSGSDGLSKLNEEIETINKEKEGIQNEFNQLKEENNKIQEELEQKNQELI 834
Query: 1943 DLENQKETVSKELALSVSREQKLASDLKAL-SEKEESTKNQLLIQTEQNKQLELEIEKLY 1767
L+ +KE +S +L +L +L + ++KEE T+ + +Q E NK L+ E E+L
Sbjct: 835 KLKEEKEKLSLDLTNGNDGINQLNENLNQIKNDKEELTEKNIQLQNEINK-LKSENEELT 893
Query: 1766 GSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGR 1587
++ +E LK NE++ ++ +++ ++KQ NIE+E
Sbjct: 894 NNI---SIEKEGLKQVNEEV-----------NAIKEERDELVKQIRNIEEE--------- 930
Query: 1586 SATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQD 1407
+KV + S + E ++ + ++ KEEV N L+N + +Q +E+++
Sbjct: 931 ----KRKVEEELNLNGSELNERIIQISNE----KEEVSQECNELKNSLKELQNKIEEIEQ 982
Query: 1406 TKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNN 1227
K + +++ LQ E++ + + LK + + +Q E Q ++
Sbjct: 983 EKE---GNEISKKEQIEELQEEINERDNDIKNLKEEIERIQKEVQEKEED---------- 1029
Query: 1226 VMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL 1065
+ I+ + LK EL ++ Q+ ++EER ES +S+E E K ++
Sbjct: 1030 --KEQISTTEEVEELKNEL-IETQRL--LEEERKEKES----ISNEFEETKEQV 1074
>ref|XP_001323236.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121906097|gb|EAY11013.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 2458
Score = 114 bits (284), Expect = 2e-22
Identities = 146/631 (23%), Positives = 268/631 (42%), Gaps = 26/631 (4%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEAN------NNLLEQKDNIIVELSHK 2139
E ++L E +LQ L+Q+N ++ +I+ N NN E+ N I EL +
Sbjct: 340 ENAKLQTENTNTVDKLQSEIEKLKQENSELQNQIQENEDGWNDNNNEEELQNQITELQKQ 399
Query: 2138 LQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFM 1959
L+EN++ S + EQ+ + + ++ + LK+ L+ A D
Sbjct: 400 LEENKKSYS------EETEQLKQIIDDDSKQ-----------IEDLKQKLAEAQDHEGNS 442
Query: 1958 EKQLQDLENQKETVSKELA--LSVSREQKLASD-----LKALSEKEESTKNQ---LLIQT 1809
+ QL L+ +K+ + K+L + R+ K +D + L+E+ S + Q L QT
Sbjct: 443 DSQLAKLQTEKQQLDKKLVDVANALRKLKTKNDNDQATISKLNEENSSLQKQIEELKQQT 502
Query: 1808 EQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDI 1629
N E EI+ L LQ Q++N +K NE + KS E++ Q++ I +
Sbjct: 503 ANNASYEAEIQNLKKQLQDLQIQNDDIKTENEHLQQEM-FENNKSEEIEQQKKQISELQ- 560
Query: 1628 NIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRN 1449
KE+ +++++ N + + + + + +K + L EE+ N + N
Sbjct: 561 ---------KEISSKSSEIQAKNDE----IENLNKEIEQIKKENQELNEELFQNNENNSN 607
Query: 1448 DAQM--VQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDES 1275
D ++ ++ ++ +Q S+L + +V L+ E++ K+Q+ QDE+
Sbjct: 608 DEEIEKLKTQIQSLQKEISDLSQQNNNYKSQVEELKEELE-----------KHQSEQDEN 656
Query: 1274 QRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVV-ESEHNVL 1098
W + + S+N NL+ Q LK +L+ QK Q QEE E+E L
Sbjct: 657 G------WGEENESEELKSENENLKKQIEELKEQLN---QKEDQGQEENGWCNENETEDL 707
Query: 1097 SSEVENLKSE---LKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL 927
SE+E LK E LK++ + E ++ E+ + E+ E + ++
Sbjct: 708 KSEIEQLKKENETLKQNNETESLKKQIEELKEQLKQKEDQGQEENGWGEENETEDYKSQI 767
Query: 926 ICLRNE----NAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKE 759
L NE N K+K+ A S+ E + + ++ NG + N +
Sbjct: 768 SALENEKRTLNKKIKDLA-------NGLKTLKSKNEKLEQQLKENANNGNND-----NSK 815
Query: 758 EDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXX 579
+ S + + K T LEF+ ++L E + + + NKL +TLSD
Sbjct: 816 DISVEFNETEEKITELEFENEELRRNNESLSEEKKTLHKQNNKLVSENKTLSD------E 869
Query: 578 XXXXXIRVRSLKKENTRLRSEMKGELTPSRS 486
+V L++E +E++ E+ RS
Sbjct: 870 VSTLREQVEELEEETISTSNELRSEIEHLRS 900
Score = 101 bits (251), Expect = 2e-18
Identities = 175/860 (20%), Positives = 335/860 (38%), Gaps = 125/860 (14%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEE 2121
+V L EE ++H E EN ++NE LK E N NL +Q + + +L+ K + +E
Sbjct: 638 QVEELKEELEKHQSEQDEN--GWGEENESEELKSE-NENLKKQIEELKEQLNQKEDQGQE 694
Query: 2120 QRSALQN----DMQS-VEQMHAVSQT-----EREELNRQLVLLRDDVNHLKEALSMAVDD 1971
+ D++S +EQ+ ++T E E L +Q+ L++ LK+ ++
Sbjct: 695 ENGWCNENETEDLKSEIEQLKKENETLKQNNETESLKKQIEELKE---QLKQKEDQGQEE 751
Query: 1970 RAFMEK--------QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLL- 1818
+ E+ Q+ LEN+K T++K++ + LA+ LK L K E + QL
Sbjct: 752 NGWGEENETEDYKSQISALENEKRTLNKKI-------KDLANGLKTLKSKNEKLEQQLKE 804
Query: 1817 ------------IQTEQNK------QLELEIEKL-YGSLQMKQMENTLLKDGN------- 1716
I E N+ +LE E E+L + + + + TL K N
Sbjct: 805 NANNGNNDNSKDISVEFNETEEKITELEFENEELRRNNESLSEEKKTLHKQNNKLVSENK 864
Query: 1715 ----------EKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKK 1566
E++ +L + + S E++ + E + + + E EL +TK + + +
Sbjct: 865 TLSDEVSTLREQVEELEEETISTSNELRSEIEHLRSELVVREQELEQTKNNNNNVNNNEN 924
Query: 1565 VNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSE--- 1395
NS+ + S E + +K + LK+ N N+ + + + + ++++D K E
Sbjct: 925 NNSNVHSDQSIYEEKISLLKQQLEELKQSQSSNNNNEELEKENISLK-KEIEDLKQENEG 983
Query: 1394 ----LFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNN 1227
LF E + E+ ++ + ELK+K ++ + + + N
Sbjct: 984 LQNQLFEGGETNENNNQEKEDEIHKLKSEIEELKKKLESSEQNKEEENNGWGDENTETEN 1043
Query: 1226 VMSKNINLESQNRSLKAELHLQAQKAFQIQEER------------NVVESEHNVLSSEVE 1083
+ + +E N+ L + +K +I+E + N E E N S+VE
Sbjct: 1044 IDNLKSEIEELNKKLDESIKSNDEKQKKIEEMKQENEELQTQLFENNSEEEINKFKSQVE 1103
Query: 1082 NLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENA 903
L +L+ES E Q+ E+ L + EE+ ++ E+ L+NE +
Sbjct: 1104 ELTQKLQESNQKNEELQSQTE---KQNNEIDDLKKQK----EEENEKLQKEISDLKNEIS 1156
Query: 902 KLKN-------------EALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQ-- 768
+L+ E L + ++ +++ + + K N N + Q
Sbjct: 1157 QLQQKEEENGSDLQKQIEVLKQTNEKNDEDIEQLAKQIDELQTEKEKQNEEINDLKSQLQ 1216
Query: 767 -------NKEEDSSGVDLLKNKCTRLE---FQVQKLSEKAEMFETKSREAQQMANKLEEM 618
E+ + +D LK + L+ F++ EK E E +++ KLEE
Sbjct: 1217 NVSEIKSENEKQKNEIDDLKKENEELQTQLFEIGNNQEKEEEIHKLKSEIEELKKKLEES 1276
Query: 617 QQ-----TLSDMXXXXXXXXXXXIRVRS----LKKENTRLRSEMK--------------- 510
+Q + ++ R+ S LKK+N+ L+ E K
Sbjct: 1277 EQNKEEENIDNLKSENETLKEEIKRLESDNEQLKKQNSELQQENKSLHQQQSKEEEENGW 1336
Query: 509 GELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSE-TQEIDTLM 333
GE S K S K+I +E L Q + T + +I L
Sbjct: 1337 GEENESEELKSENESLKKQI---EELKEQLKQKEDQGQEENGWGDENETEDYKSQISALE 1393
Query: 332 DDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWG-GIDMNSIEKQLKE 156
++ R ++ ++L++ ++L+Q ++ N E+++ E
Sbjct: 1394 NEKRTLNKKIKDLANGLKTLKSKNEKLEQQLKDINSNNSTNDNSKDISVEFNETEEKITE 1453
Query: 155 LNIHVMQLVEHNTRLKKDVK 96
L +L +N L ++ K
Sbjct: 1454 LEFENEELRRNNESLSEEKK 1473
Score = 101 bits (251), Expect = 2e-18
Identities = 140/713 (19%), Positives = 309/713 (43%), Gaps = 37/713 (5%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEE 2121
E+S+L ++E+++ +LQ+ L+Q NE N+ +EQ I EL + ++ E
Sbjct: 1154 EISQLQQKEEENGSDLQKQIEVLKQTNEK-------NDEDIEQLAKQIDELQTEKEKQNE 1206
Query: 2120 QRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALS---MAVDDRAFMEKQ 1950
+ + L++ +Q+V ++ + ++ ++ E+ DD+ E L + + E++
Sbjct: 1207 EINDLKSQLQNVSEIKSENEKQKNEI--------DDLKKENEELQTQLFEIGNNQEKEEE 1258
Query: 1949 LQDLENQKETVSKELALS-VSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEK 1773
+ L+++ E + K+L S ++E++ +LK+ +E + +L EQ K+ E+++
Sbjct: 1259 IHKLKSEIEELKKKLEESEQNKEEENIDNLKSENETLKEEIKRLESDNEQLKKQNSELQQ 1318
Query: 1772 LYGSLQMKQM------------ENTLLKDGNEKIYDLCKLL--ATKSREVQGQQEGILKQ 1635
SL +Q E+ LK NE + + L K +E QGQ+E
Sbjct: 1319 ENKSLHQQQSKEEEENGWGEENESEELKSENESLKKQIEELKEQLKQKEDQGQEENGWGD 1378
Query: 1634 DINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEV--LGNIN 1461
+ ED ++ + + K K+ + L +K L++++ + + N
Sbjct: 1379 ENETEDYKSQISALENEKRTLNK-------KIKDLANGLKTLKSKNEKLEQQLKDINSNN 1431
Query: 1460 SLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQD 1281
S ++++ + V + ++ +EL E E + L E +Q +L +N+TL D
Sbjct: 1432 STNDNSKDISVEFNETEEKITELEFENEELRRNNESLSEEKKTLQKQNNKLVSENKTLSD 1491
Query: 1280 ESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERN-------- 1125
E +++ + +S + L S+ L++EL L+ Q+ Q + N
Sbjct: 1492 EVSTLREQVEELE---EETISTSNELRSEIEHLRSELVLREQELEQTKNNNNNVNNNENN 1548
Query: 1124 --VVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEK 951
V S+ ++ ++ LK +L+E K + D E ++E
Sbjct: 1549 NSNVHSDQSIYEEKISLLKQQLEELK----------------QQQQKPFDHEDNNDSDE- 1591
Query: 950 LMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREF 771
+ ++ E+ L+ EN +L+N+ L+E + N + + + + L S+ + +
Sbjct: 1592 INKLKKEIEDLKQENEELQNQ-LFEGGETNENN-NQEKEDEIHKLKSEIEELKKKLESSE 1649
Query: 770 QNKEEDSSG-------VDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQ 612
QNKEE+++G + ++N + +E +KL+E ++ + K ++ +++ KL+E Q
Sbjct: 1650 QNKEEENNGWGDENTETENIENLKSEIEELNKKLNELSKSNDEKQKKIEELEQKLQESQN 1709
Query: 611 TLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDED 432
+ + LK++ +LR + +T S+ + + K+I +E
Sbjct: 1710 NKDE----------EEENIEDLKEQLEQLR---RDAITKSKQDQEEIENLKKQI---EEK 1753
Query: 431 DTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSL 273
+ + + I + +EI+ L ++ +K + + + L
Sbjct: 1754 EADIEEITEELEQLRKDSITKAKQDQEEIEKLQNEIQKQKEIIDNLNAEIDEL 1806
Score = 99.4 bits (246), Expect = 6e-18
Identities = 153/771 (19%), Positives = 321/771 (41%), Gaps = 92/771 (11%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDN-----------------IIV 2154
E + + E ++ + L+ + E++ K+E++ E+++N I
Sbjct: 993 ETNENNNQEKEDEIHKLKSEIEELKKKLESSEQNKEEENNGWGDENTETENIDNLKSEIE 1052
Query: 2153 ELSHKLQENEEQRSALQNDMQSVEQMHAVSQTE------REELNRQLVLLRDDVNHLKEA 1992
EL+ KL E+ + Q ++ ++Q + QT+ EE+N+ + + L+E+
Sbjct: 1053 ELNKKLDESIKSNDEKQKKIEEMKQENEELQTQLFENNSEEEINKFKSQVEELTQKLQES 1112
Query: 1991 LSMAVDDRAFMEKQ---LQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQL 1821
+ ++ EKQ + DL+ QKE +++L +S L +++ L +KEE + L
Sbjct: 1113 NQKNEELQSQTEKQNNEIDDLKKQKEEENEKLQKEIS---DLKNEISQLQQKEEENGSDL 1169
Query: 1820 LIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGIL 1641
KQ+E +LK NEK + + LA + E+Q ++E
Sbjct: 1170 ------QKQIE------------------VLKQTNEKNDEDIEQLAKQIDELQTEKE--- 1202
Query: 1640 KQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSL--KEEVLGN 1467
KQ+ I D ++ + V +++K N ++ + + ++ +F + +E
Sbjct: 1203 KQNEEINDLKSQLQNV----SEIKSENEKQKNEIDDLKKENEELQTQLFEIGNNQEKEEE 1258
Query: 1466 INSLRNDAQMVQVALEQMQDTKSE-----LFAEAEIRAQEVLRLQAEVDAIQHILIELKR 1302
I+ L+++ + ++ LE+ + K E L +E E +E+ RL+++ + ++ EL++
Sbjct: 1259 IHKLKSEIEELKKKLEESEQNKEEENIDNLKSENETLKEEIKRLESDNEQLKKQNSELQQ 1318
Query: 1301 KNQTL-QDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEER- 1128
+N++L Q +S+ + W + + S+N +L+ Q LK +L QK Q QEE
Sbjct: 1319 ENKSLHQQQSKEEEENGWGEENESEELKSENESLKKQIEELKEQL---KQKEDQGQEENG 1375
Query: 1127 --------------NVVESEHNVLSSEVENLKSELK------------------------ 1062
+ +E+E L+ ++++L + LK
Sbjct: 1376 WGDENETEDYKSQISALENEKRTLNKKIKDLANGLKTLKSKNEKLEQQLKDINSNNSTND 1435
Query: 1061 ESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKL-------------MRILDELIC 921
SKD+ F E + E L + +EEK + DE+
Sbjct: 1436 NSKDISVEFNETEEKITELEFENEELRRNNESLSEEKKTLQKQNNKLVSENKTLSDEVST 1495
Query: 920 LRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGV 741
LR + +L+ E + ++ R + R+E VL + L + N N E ++S V
Sbjct: 1496 LREQVEELEEETISTSNEL-RSEIEHLRSEL--VLREQELEQTKNNNNNVNNNENNNSNV 1552
Query: 740 ----DLLKNKCTRLEFQVQKLSEKAEM-FETKSREAQQMANKLEEMQQTLSDMXXXXXXX 576
+ + K + L+ Q+++L ++ + F+ + NKL++
Sbjct: 1553 HSDQSIYEEKISLLKQQLEELKQQQQKPFDHEDNNDSDEINKLKK--------------- 1597
Query: 575 XXXXIRVRSLKKENTRLRSEM-KGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXX 399
+ LK+EN L++++ +G T + + +E I ++ E+ ++
Sbjct: 1598 -----EIEDLKQENEELQNQLFEGGETNENNNQEKEDE-IHKLKSEIEELKKKLESSEQN 1651
Query: 398 XXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQ 246
+ET+ I+ L + + +++ +K Q ++EL+Q
Sbjct: 1652 KEEENNGWGDENTETENIENLKSEIEELNKKLNELSKSNDEKQKKIEELEQ 1702
Score = 99.4 bits (246), Expect = 6e-18
Identities = 142/761 (18%), Positives = 318/761 (41%), Gaps = 75/761 (9%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNN--LLEQKDNIIVELSHKLQE 2130
+E+++ +E + E Q+ ++Q+NE++ ++ NN+ + + + + EL+ KLQE
Sbjct: 1052 EELNKKLDESIKSNDEKQKKIEEMKQENEELQTQLFENNSEEEINKFKSQVEELTQKLQE 1111
Query: 2129 ----NEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNH-------------- 2004
NEE +S + ++ + + E E+L +++ L+++++
Sbjct: 1112 SNQKNEELQSQTEKQNNEIDDLKKQKEEENEKLQKEISDLKNEISQLQQKEEENGSDLQK 1171
Query: 2003 ----LKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEES 1836
LK+ +D + KQ+ +L+ +KE ++E+ S+ Q + S++K+ +EK+++
Sbjct: 1172 QIEVLKQTNEKNDEDIEQLAKQIDELQTEKEKQNEEINDLKSQLQNV-SEIKSENEKQKN 1230
Query: 1835 TKNQLLIQTEQ----------NKQLELEIEKLYGSL-----------QMKQMEN-TLLKD 1722
+ L + E+ N++ E EI KL + Q K+ EN LK
Sbjct: 1231 EIDDLKKENEELQTQLFEIGNNQEKEEEIHKLKSEIEELKKKLEESEQNKEEENIDNLKS 1290
Query: 1721 GNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVG-----RSATDMKKVNS 1557
NE + + K L + + +++ Q + +++ ++ + ++ +E + ++K N
Sbjct: 1291 ENETLKEEIKRLESDNEQLKKQNSELQQENKSLHQQQSKEEEENGWGEENESEELKSENE 1350
Query: 1556 DAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAE 1377
++ + E L +D +E G+ N+ + + + +++ K L + +
Sbjct: 1351 SLKKQIEELKEQLKQKEDQ--GQEENGWGD----ENETEDYKSQISALENEKRTLNKKIK 1404
Query: 1376 IRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLES 1197
A + L+++ + ++ L ++ N T N+K++ N K LE
Sbjct: 1405 DLANGLKTLKSKNEKLEQQLKDINSNNST-----NDNSKDI---SVEFNETEEKITELEF 1456
Query: 1196 QNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEI 1017
+N L+ +++ +Q++ N + SE+ LS EV L+ +++E L E
Sbjct: 1457 ENEELRRNNESLSEEKKTLQKQNNKLVSENKTLSDEVSTLREQVEE----------LEEE 1506
Query: 1016 LLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSR 837
+ E+ S +IE R +L+ EL +N N + N ++ NV +
Sbjct: 1507 TISTSNELRS-EIEHLR---SELVLREQELEQTKNNNNNVNN------NENNNSNVHSDQ 1556
Query: 836 A---EAMSVLISKSLGNGRANQREFQNKE-EDSSGVDLLKNKCTRLEFQVQKL------- 690
+ E +S+L + + Q+ F +++ DS ++ LK + L+ + ++L
Sbjct: 1557 SIYEEKISLLKQQLEELKQQQQKPFDHEDNNDSDEINKLKKEIEDLKQENEELQNQLFEG 1616
Query: 689 --------SEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKE- 537
EK + E +++ KLE +Q + + +LK E
Sbjct: 1617 GETNENNNQEKEDEIHKLKSEIEELKKKLESSEQNKEEENNGWGDENTETENIENLKSEI 1676
Query: 536 ---NTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTR 366
N +L K + + E + N DE++ + I
Sbjct: 1677 EELNKKLNELSKSNDEKQKKIEELEQKLQESQNNKDEEEENIEDLKEQLEQLRRDAITKS 1736
Query: 365 TSETQEIDTLMDDNRKYWNRVSHFTKQTQSL-QNSVQELQQ 246
+ +EI+ L + + T++ + L ++S+ + +Q
Sbjct: 1737 KQDQEEIENLKKQIEEKEADIEEITEELEQLRKDSITKAKQ 1777
Score = 94.4 bits (233), Expect = 2e-16
Identities = 162/786 (20%), Positives = 334/786 (42%), Gaps = 52/786 (6%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEA----NNNLLEQKDNIIVELS--- 2145
K++S + E ++ EL+ LR+ NE + + + NN L+ + + E+S
Sbjct: 1438 KDISVEFNETEEKITELEFENEELRRNNESLSEEKKTLQKQNNKLVSENKTLSDEVSTLR 1497
Query: 2144 HKLQENEEQRSALQNDMQS-VEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDR 1968
+++E EE+ + N+++S +E + + +EL Q ++VN+ + S D+
Sbjct: 1498 EQVEELEEETISTSNELRSEIEHLRSELVLREQELE-QTKNNNNNVNNNENNNSNVHSDQ 1556
Query: 1967 AFMEKQLQDLENQKETVSKELALSVSREQ--------KLASDLKALSEKEESTKNQLLIQ 1812
+ E+++ L+ Q E + ++ E KL +++ L ++ E +NQL
Sbjct: 1557 SIYEEKISLLKQQLEELKQQQQKPFDHEDNNDSDEINKLKKEIEDLKQENEELQNQLFEG 1616
Query: 1811 TEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQD 1632
E N+ + Q K+ E LK +I +L K L + + + + G ++
Sbjct: 1617 GETNEN----------NNQEKEDEIHKLKS---EIEELKKKLESSEQNKEEENNGWGDEN 1663
Query: 1631 I---NIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNIN 1461
NIE+ + +E+ + ++ K N + K+ + + L +++ K+E NI
Sbjct: 1664 TETENIENLKSEIEELNKKLNELSKSNDEKQKKIEELEQKLQESQNN----KDEEEENIE 1719
Query: 1460 SLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQT--- 1290
L+ Q+ Q+ + + +K + E E +++ +A+++ I L +L++ + T
Sbjct: 1720 DLKE--QLEQLRRDAITKSKQDQ-EEIENLKKQIEEKEADIEEITEELEQLRKDSITKAK 1776
Query: 1289 --------LQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQE 1134
LQ+E Q+ + + N A ++ + K E+++ LK EL + + Q
Sbjct: 1777 QDQEEIEKLQNEIQKQKEIIDNLNAEIDELGEK----EAEHEDLKDELQQLRKDSLQ--- 1829
Query: 1133 ERNVVESEHNVLSSEVENLKSELKESK--------DLEGYFLRLFEIL--LGQHVEVASL 984
+ + ++E + L++EV NLK EL+ K D E + L EI+ L +E +
Sbjct: 1830 KAKIDQAEIDRLNAEVSNLKFELENGKENIWGDDDDNEKHKETLTEIIEKLKSEIEDKNS 1889
Query: 983 DIESCRFAEEKLMRILDELICLRNENAKLKNE---ALYEYHDYERKNVSGSRAEAMSVLI 813
+IE EE++ + D ++ EN KLK E AL + + N ++ +
Sbjct: 1890 EIEK---LEEEISQFEDPTE-VKQENKKLKEELDQALRQNAELGNVNEENNKLREQ---L 1942
Query: 812 SKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQV-QKLSEKAEMFETKSREAQQMA 636
+S+ E + KE++ L + L+F++ ++ ++ +++S E +
Sbjct: 1943 KQSIDTNELKTLEKKLKEKEEEN-QKLHDDLNTLQFELNNSIAGLPKINQSESMEIRDEV 2001
Query: 635 NKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIK 456
+L + LS++ + L++E L S++ E R+ +E ++
Sbjct: 2002 ERLANENKKLSEL-------------TKKLEEEKNFLVSQL--ENVVQRNDYEKELQNVE 2046
Query: 455 EINI----GDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTK 288
E+ + ++D+ L+Q +T E + ++ + + ++ K
Sbjct: 2047 ELKLKLKKAEKDNEELLQQIDELVEQN----ETENHEKSDAESELKSLKAELAKLKDSEK 2102
Query: 287 QTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEK----QLKELNIHVMQLVEHN 120
+ Q L+ V EL Q D ++ E Q EL V L N
Sbjct: 2103 EYQVLREEVDELTQKIEESETINKELKTIIDQNDTSAAENMYKAQFDELKALVSDLKSQN 2162
Query: 119 TRLKKD 102
LKKD
Sbjct: 2163 EDLKKD 2168
Score = 77.4 bits (189), Expect = 3e-11
Identities = 147/742 (19%), Positives = 298/742 (40%), Gaps = 56/742 (7%)
Frame = -1
Query: 2093 QSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVS 1914
+S+ + + + + + E Q+ D + +E + ++ A +K++++ E E ++
Sbjct: 27 KSLSKENDILKRTQAEYQAQIQKCSDALIEERETTATLTNELAECDKKIEEKEKLIEDLA 86
Query: 1913 KELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENT 1734
KE+ E+ KN ++ + LE +++ ++ + EN
Sbjct: 87 KEI---------------------ENMKNTTSTASQNDSGLEEVVQEFEQKIETLESENK 125
Query: 1733 LLKDGNEKIY-------DLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATD 1575
+KD N ++ +L L+T+S E+Q + E I +D + E+ L +T
Sbjct: 126 TMKDQNSELQQQIQQYKELTDKLSTESTELQQKMENIKSEDKSAEETLLQT--------- 176
Query: 1574 MKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSE 1395
SD +++ + E L K S ++ N N+ AQ Q Q+ D K++
Sbjct: 177 ----ISDQDIQINKLKEELEQAKLAANSSEQ----NTNAF---AQKEQELNAQITDLKNQ 225
Query: 1394 LFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSK 1215
L A+ + + E+ L+A++ + + +N+ L+ ESQ++A K
Sbjct: 226 LAAKDSL-SDEIASLKAQIAELNQNNSKSSEENEQLKAESQKDASS-----------DDK 273
Query: 1214 NINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNV--LSSEVENLKSELKESKDLEG 1041
N +L +R KA + L+ Q A + QE ++ S + ++E +N++ E +S+ +E
Sbjct: 274 NSDL---SRLKKAVVQLKKQIAQKDQEINDLKTSNMQLQNFNNETQNVEIEKYKSQIIE- 329
Query: 1040 YFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYE 861
F ++ E L E A L E+ + ++ E+ L+ EN++L+N+ + E D
Sbjct: 330 -FQKIIESL---KAENAKLQTENTNTVD----KLQSEIEKLKQENSELQNQ-IQENEDGW 380
Query: 860 RKNVSGSRAEAMSVLISKSLGNGRANQREFQNK-----EEDSSGVDLLKNK--------- 723
N + + + K L + + E + ++DS ++ LK K
Sbjct: 381 NDNNNEEELQNQITELQKQLEENKKSYSEETEQLKQIIDDDSKQIEDLKQKLAEAQDHEG 440
Query: 722 -----CTRLEFQVQKLSEK-------AEMFETKSREAQQMANKLEE----MQQTLSDMXX 591
+L+ + Q+L +K +TK+ Q +KL E +Q+ + ++
Sbjct: 441 NSDSQLAKLQTEKQQLDKKLVDVANALRKLKTKNDNDQATISKLNEENSSLQKQIEELKQ 500
Query: 590 XXXXXXXXXIRVRSLKK--------------ENTRLRSEMKGELTPSRSFKHREGSFIKE 453
+++LKK EN L+ EM E S + ++ I E
Sbjct: 501 QTANNASYEAEIQNLKKQLQDLQIQNDDIKTENEHLQQEM-FENNKSEEIEQQKKQ-ISE 558
Query: 452 INIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLM---DDNRKYWNRVSHFTKQT 282
+ + IQ +I+ E QE++ + ++N + Q
Sbjct: 559 LQKEISSKSSEIQAKNDEIENLNKEIEQIKKENQELNEELFQNNENNSNDEEIEKLKTQI 618
Query: 281 QSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKD 102
QSLQ + +L Q N+ + Q++EL +L +H + ++
Sbjct: 619 QSLQKEISDLSQ-------------------QNNNYKSQVEELK---EELEKHQSEQDEN 656
Query: 101 VKFGFAWANSMHDLNGQEQKLK 36
G+ N +L + + LK
Sbjct: 657 ---GWGEENESEELKSENENLK 675
Score = 73.9 bits (180), Expect = 3e-10
Identities = 134/643 (20%), Positives = 276/643 (42%), Gaps = 84/643 (13%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEAN--------NNLLEQKDNI---- 2160
+E+ L ++ ++ +++E L Q +D K + + N + +QK+ I
Sbjct: 1741 EEIENLKKQIEEKEADIEEITEELEQLRKDSITKAKQDQEEIEKLQNEIQKQKEIIDNLN 1800
Query: 2159 --IVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALS 1986
I EL K E+E+ + LQ + Q + Q E + LN ++ L+ ++ + KE +
Sbjct: 1801 AEIDELGEKEAEHEDLKDELQQLRKDSLQKAKIDQAEIDRLNAEVSNLKFELENGKENIW 1860
Query: 1985 MAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSE----KEESTK---- 1830
DD EK + L E + E+ S +KL ++ + K+E+ K
Sbjct: 1861 GDDDDN---EKHKETLTEIIEKLKSEIEDKNSEIEKLEEEISQFEDPTEVKQENKKLKEE 1917
Query: 1829 -NQLLIQT-------EQNKQLELEIEKLYGSLQMKQMENTLLK--DGNEKIYDLCKLLAT 1680
+Q L Q E+N +L ++++ + ++K +E L + + N+K++D L T
Sbjct: 1918 LDQALRQNAELGNVNEENNKLREQLKQSIDTNELKTLEKKLKEKEEENQKLHDD---LNT 1974
Query: 1679 KSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDD 1500
E+ G+ K IN + + EV R A + KK+ S+ K+ L+ ++
Sbjct: 1975 LQFELNNSIAGLPK--INQSESMEIRDEVERLANENKKL-SELTKKLEEEKNFLVSQLEN 2031
Query: 1499 VFSLK--EEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQ 1326
V E+ L N+ L+ + + E++ EL + E E ++E+ +++
Sbjct: 2032 VVQRNDYEKELQNVEELKLKLKKAEKDNEELLQQIDELVEQNETENHEKSDAESELKSLK 2091
Query: 1325 HILIELKRKNQTLQ-------------DESQRNAKELWNA-------------KARLNNV 1224
L +LK + Q +ES+ KEL KA+ + +
Sbjct: 2092 AELAKLKDSEKEYQVLREEVDELTQKIEESETINKELKTIIDQNDTSAAENMYKAQFDEL 2151
Query: 1223 MSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVES-------EHNVLSSEVENLKSEL 1065
+ +L+SQN LK + Q+ ++ EE+ + + +++ LSS VE L +E+
Sbjct: 2152 KALVSDLKSQNEDLKKDSENSKQEITKLTEEKTELNANIEKLTQDNSNLSSNVEKLTNEI 2211
Query: 1064 KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFA-----EEKLMRILDELICLRNENAK 900
K + E ++ VA+ +++ A E++ ++ E L +N +
Sbjct: 2212 SNLK----FQPTAQENVVPAETPVAN-EVKPSEEAVSTPNEDEKAKLESEKEELVKKNDE 2266
Query: 899 LKNEALYEYHDYERKNVSGSRAEAMSVLISK---SLGNGRANQREFQNK-EEDSSGVDLL 732
+ + + ++ E++N ++ + + ++ SL N + +E + + ++ ++ V L
Sbjct: 2267 MMKQIVLMKNEIEKQNKEFAQMQERFIKANEENMSLRNVASKNKELETQLDQKTANVLSL 2326
Query: 731 KNKCTRLEFQVQ-----KLSEKAEMF---ETKSREAQQMANKL 627
+ L+ + Q KL++ A+ F K R +Q N+L
Sbjct: 2327 RKDIDNLKIEFQKDLDAKLAKAAKEFNDLRKKFRVVEQQRNQL 2369
>ref|XP_001581403.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121915630|gb|EAY20417.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 4263
Score = 113 bits (282), Expect = 4e-22
Identities = 134/667 (20%), Positives = 294/667 (44%), Gaps = 17/667 (2%)
Frame = -1
Query: 2297 VSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEE- 2121
+ +L E +QH + E +A QKN++ +IE + Q+D I +L ++++++++
Sbjct: 1678 IKQLQSEIEQHKQTIAER-DAEIQKNKE---EIEQQKQTISQRDETIKQLQNEIEQHKQT 1733
Query: 2120 --QRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL 1947
QR A ++ Q + E+E+L +QL + ++ K+ ++ + A ++K
Sbjct: 1734 ISQRDAEIEQLKQTVQQSDQTIAEKEDLIKQL---QSEIEQHKQTIA---ERDAEIQKNK 1787
Query: 1946 QDLENQKETVSKELALSVSREQKLASDLKALSEKE---ESTKNQLLIQTEQNKQLELEIE 1776
+++E QK+T+S+ + ++ + + ++++E E K + + KQL+ EIE
Sbjct: 1788 EEIEQQKQTISQRDESIKQMQSEIEQNKQTIADREKEIEQHKQTIAERDNSIKQLQEEIE 1847
Query: 1775 KLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKE 1596
+ ++ + E ++ E+I + + + E + ++ IL+ + N E+ + + KE
Sbjct: 1848 QHKQTIAERDAE---IQKNKEEIQQKNEAINALTNEGEEKRLKILELEANNENLINKVKE 1904
Query: 1595 VGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLK----------EEVLGNINSLRND 1446
+ S +D+ + + V + + + + + L+ EE I SL N
Sbjct: 1905 LNDSVSDLNLSTENQNSVVKQMTDEIKDLNKQIHELEVKSENQQKQIEEKDKEIQSLTNT 1964
Query: 1445 AQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRN 1266
+ ++++Q+ L + + LQ +V + L E K +N+ L + Q
Sbjct: 1965 KAQNEELIKKLQEEVENLTNTKNQNEETIKNLQEQVQS----LTETKNQNEDLIKKQQEQ 2020
Query: 1265 AKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEV 1086
+ L N K + NL+ Q +SL +A I++ + V+S ++
Sbjct: 2021 IQSLTNTKNENEETIK---NLQEQVQSL---TETKATNEETIKKLQGEVQSLTETKATNE 2074
Query: 1085 ENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNEN 906
E +K + +E + L E++ E+ +L + EE++ ++ +E+ L+ +N
Sbjct: 2075 EQIKKQQEEIQSLSNTKNENEELIKKLQEEIQNLTNTKTQ-NEEQIKKLQEEIQNLQKQN 2133
Query: 905 AKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKN 726
A+ K++ + E+ + + +S S E + I+ NQ QN E+D+ + L
Sbjct: 2134 AE-KDDKINEF-NAKLSTLSSSSDELTTKFIN---AQNEINQLTKQNNEKDNL-ISQLNQ 2187
Query: 725 KCTRLEFQVQKL-SEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRS 549
K + LE +L +EK+++ + K+ Q+ A LE+ + +
Sbjct: 2188 KISDLENAKSQLENEKSQLIQEKTNLEQEKAQLLEQKKNLEEEKQKLETEKTNLEQEKAK 2247
Query: 548 LKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDT 369
L +E T L E + + + + I+E +++ LI+ I+
Sbjct: 2248 LIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEE 2307
Query: 368 RTSETQE 348
+T+ QE
Sbjct: 2308 KTNLEQE 2314
Score = 100 bits (250), Expect = 2e-18
Identities = 139/717 (19%), Positives = 307/717 (42%), Gaps = 41/717 (5%)
Frame = -1
Query: 2273 KQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDM 2094
KQ T E+++ L ++ ++ +K E +E+KD I L++ +NEE LQ ++
Sbjct: 1924 KQMTDEIKD----LNKQIHELEVKSENQQKQIEEKDKEIQSLTNTKAQNEELIKKLQEEV 1979
Query: 2093 QSVEQMHAVSQTEREELNRQLVLLRDDVNH-------LKEALSMAVDDRAFMEKQLQDLE 1935
+++ ++ + L Q+ L + N +E + + + E+ +++L+
Sbjct: 1980 ENLTNTKNQNEETIKNLQEQVQSLTETKNQNEDLIKKQQEQIQSLTNTKNENEETIKNLQ 2039
Query: 1934 NQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQL-------ELEIE 1776
Q +++++ A + +KL ++++L+E + + + Q+ Q E+ + L E I+
Sbjct: 2040 EQVQSLTETKATNEETIKKLQGEVQSLTETKATNEEQIKKQQEEIQSLSNTKNENEELIK 2099
Query: 1775 KLYGSLQ----MKQMENTLLKDGNEKIYDLCKLLATKSREVQ----------GQQEGILK 1638
KL +Q K +K E+I +L K A K ++ + +
Sbjct: 2100 KLQEEIQNLTNTKTQNEEQIKKLQEEIQNLQKQNAEKDDKINEFNAKLSTLSSSSDELTT 2159
Query: 1637 QDINIEDELAR-TKEVGRSATDMKKVNS------DAGAKVSGILEMLLPMKDDVFSLKEE 1479
+ IN ++E+ + TK+ + ++N +A +++ L+ K ++ K +
Sbjct: 2160 KFINAQNEINQLTKQNNEKDNLISQLNQKISDLENAKSQLENEKSQLIQEKTNLEQEKAQ 2219
Query: 1478 VLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRK 1299
+L +L + Q ++ ++ K++L E QE +L E ++ +L +
Sbjct: 2220 LLEQKKNLEEEKQKLETEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEE 2279
Query: 1298 NQTLQDESQRNAKELWNAKARLNNVMSKNINLESQN-RSLKAELHLQAQKAFQIQEERNV 1122
L+ E + +E N + ++ + NLE + + ++ + +L+ +KA I+E+ N+
Sbjct: 2280 KTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKPIEEKTNLEQEKAKLIEEKTNL 2339
Query: 1121 VESEHNVLSSEVENLKSE----LKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEE 954
E E L E NL+ E ++E +LE +L E E A L E +E
Sbjct: 2340 -EQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQE 2398
Query: 953 KLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQRE 774
K ++++E L E AKL E+ N+ +A+ + + +
Sbjct: 2399 K-AKLIEEKTNLEQEKAKLIE---------EKTNLEQEKAKLI--------------EEK 2434
Query: 773 FQNKEEDSSGVDLLKNKCTRLEFQVQKL-SEKAEMFETKSREAQQMANKLEEMQQTLSDM 597
++E S +D KN LE + Q+L +EKA++ E K+ Q+ A LE+ + +
Sbjct: 2435 TNLEQEKSQLLDQKKN----LEEEKQRLETEKAKLIEDKTNLEQEKAQLLEQKKNLEEEK 2490
Query: 596 XXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLI 417
+ +E L S++ ++ E F ++ + D + +I
Sbjct: 2491 AKLEEEKAQAQKTIEEKDQEIEDLTSQIN---VKTKDLSLLESDF-NNMSFTNADQSTMI 2546
Query: 416 QXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQ 246
+I+ ++ +++ D+ + ++++ ++ +++QN L+Q
Sbjct: 2547 SNYEKELSDKNKEINDLQNQLKQMTQNRDELQSKSDKLNEEIEEKKNIQNLESSLEQ 2603
Score = 96.7 bits (239), Expect = 4e-17
Identities = 125/625 (20%), Positives = 268/625 (42%), Gaps = 34/625 (5%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQEN----EEQR 2115
E+EK ++ ++N +Q+ E K+ + LEQ+ ++E L+E EE++
Sbjct: 2438 EQEKSQLLDQKKNLEEEKQRLETEKAKLIEDKTNLEQEKAQLLEQKKNLEEEKAKLEEEK 2497
Query: 2114 SALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFM----EKQL 1947
+ Q ++ +Q ++ + L LL D N+ +S D++ M EK+L
Sbjct: 2498 AQAQKTIEEKDQEIEDLTSQINVKTKDLSLLESDFNN----MSFTNADQSTMISNYEKEL 2553
Query: 1946 QDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKN------QLLIQTEQNKQLEL 1785
D + + +L +L S L+E+ E KN L + ++N+ L+
Sbjct: 2554 SDKNKEINDLQNQLKQMTQNRDELQSKSDKLNEEIEEKKNIQNLESSLEQKNKENEDLKQ 2613
Query: 1784 EIEKLYGSLQMKQMENT-----LLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIE 1620
++ K G L + + T L K+ N+ + +A + E+ ++ + ++D I
Sbjct: 2614 QLNKTQGELSAQLQQKTQELENLTKEFNDLKQKSEQTIAQNNEEIANLKKNVAERDKKIS 2673
Query: 1619 DELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVL---GNINSLRN 1449
L ++KK SD + + + + ++++ +LK+ V IN L+N
Sbjct: 2674 QLLE------NEVNELKKKLSDKENENTSLKNTISERENEINNLKKNVSDKENEINQLKN 2727
Query: 1448 DAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQR 1269
+ M + L +M+D E + Q + + +++ + + DE ++
Sbjct: 2728 NLTMRETELNKMKD------EEVKNAKQIIAQKDKDLEELNGKFNDTNNNLSKANDELKQ 2781
Query: 1268 NAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSE 1089
+++ + ++ + N ES+ + L + L Q ++ ++ +S+ N L++E
Sbjct: 2782 LKEQIESLNKQIEQMKCSNNLKESEIKQLTSNLQKYKQALKELNDQNKQKDSQINQLNNE 2841
Query: 1088 VENLKSELKES----KDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELIC 921
++ L+ LK++ K+ + + E L + E A + ++K I D
Sbjct: 2842 MKELQQTLKQTQEQLKETQDQLKQTQETLATKEKEFAKSAEDLNNELKKKQQAIDDLQNN 2901
Query: 920 LRNENAKL-----KNEA-LYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNK- 762
L+ ++A+L K EA E++D ++K AE + K + +A +
Sbjct: 2902 LKQKDAELTDTKQKLEAKTNEFNDLKQK------AENEIASLRKEIEQLKAKLANTSKEL 2955
Query: 761 EEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMAN-KLEEMQQTLSDMXXXX 585
E S DL K + +L+ + K++E + +++S +N K+++MQ+ + ++
Sbjct: 2956 EASKSESDLQKKENDKLKVNLAKIAEMYKTLKSESENNSAKSNDKIKQMQEKIQNL---- 3011
Query: 584 XXXXXXXIRVRSLKKENTRLRSEMK 510
I+V +K N L +E K
Sbjct: 3012 ------EIQVEKMKLANENLTNENK 3030
Score = 95.1 bits (235), Expect = 1e-16
Identities = 159/808 (19%), Positives = 325/808 (40%), Gaps = 56/808 (6%)
Frame = -1
Query: 2282 EEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQ 2103
E+ KQ + E L+ + E I NN +EQ L + + E EE LQ
Sbjct: 1483 EQHKQTISQRDETIKQLQSEIEQHKQTIADKNNEIEQ-------LKNTISEREETIKQLQ 1535
Query: 2102 NDM----QSVEQMHAVSQTEREELNRQLVLLRDDVNHLK-------------EALSMAVD 1974
N++ Q++ + A Q +EE+ +Q + ++ N ++ E L +
Sbjct: 1536 NEIEQHKQTMAERDAEIQKNKEEIEQQKQTISNNNNEIEQLKKTISERDAEIEQLKKTIA 1595
Query: 1973 DRAFMEKQLQ-DLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNK 1797
+R KQLQ ++E K+T+S+ A +Q + + ++EKE+ K QL + EQ+K
Sbjct: 1596 ERDESIKQLQNEIEQHKQTISQRDAEIEQLKQTVQQRDQTIAEKEDLIK-QLQSEIEQHK 1654
Query: 1796 QL----ELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDI 1629
Q EIE+L Q + +K +I + +A + E+Q +E I +Q
Sbjct: 1655 QTISDKNNEIEQL---KQTVNARDEAIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQ 1711
Query: 1628 NIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRN 1449
I K++ K+ S A++ L+ + D + KE+++
Sbjct: 1712 TISQRDETIKQLQNEIEQHKQTISQRDAEIEQ-LKQTVQQSDQTIAEKEDLI-------- 1762
Query: 1448 DAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEV----DAIQHILIELKRKNQTLQD 1281
+ +Q +EQ + T +E AE + +E+ + + + ++I+ + E+++ QT+ D
Sbjct: 1763 --KQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQTISQRDESIKQMQSEIEQNKQTIAD 1820
Query: 1280 ESQRNAKELWNAKARLNNVMSKNINLESQNRSL---KAELHLQAQKAFQIQEERNVVESE 1110
+ + R N++ +E +++ AE+ ++ Q E N + +E
Sbjct: 1821 REKEIEQHKQTIAERDNSIKQLQEEIEQHKQTIAERDAEIQKNKEEIQQKNEAINALTNE 1880
Query: 1109 HN-------VLSSEVENLKSELKESKD-----------LEGYFLRLFEILLGQHVEVASL 984
L + ENL +++KE D ++ + + + ++ L
Sbjct: 1881 GEEKRLKILELEANNENLINKVKELNDSVSDLNLSTENQNSVVKQMTDEIKDLNKQIHEL 1940
Query: 983 DIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKS 804
+++S ++K + D+ I N K +NE L + E +N++ ++ + + K+
Sbjct: 1941 EVKSEN--QQKQIEEKDKEI-QSLTNTKAQNEELIKKLQEEVENLTNTKNQNEETI--KN 1995
Query: 803 LGNGRANQREFQNKEED-----SSGVDLLKNKCTRLEFQVQKLSEKAE-MFETKSREAQQ 642
L + E +N+ ED + L N E ++ L E+ + + ETK+ +
Sbjct: 1996 LQEQVQSLTETKNQNEDLIKKQQEQIQSLTNTKNENEETIKNLQEQVQSLTETKATNEET 2055
Query: 641 MANKLEEMQQTLSDMXXXXXXXXXXXIRVRSL---KKENTRLRSEMKGELTPSRSFKHRE 471
+ E+Q ++SL K EN L +++ E+ + K +
Sbjct: 2056 IKKLQGEVQSLTETKATNEEQIKKQQEEIQSLSNTKNENEELIKKLQEEIQNLTNTKTQN 2115
Query: 470 GSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFT 291
IK++ ++ K+ T +S + E+ T + + N ++ T
Sbjct: 2116 EEQIKKLQEEIQNLQKQNAEKDDKINEFNAKLSTLSSSSDELTTKFINAQ---NEINQLT 2172
Query: 290 KQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRL 111
KQ N + +L Q ++ +E +L QL++ T L
Sbjct: 2173 KQNNEKDNLISQLNQ-------------------KISDLENAKSQLENEKSQLIQEKTNL 2213
Query: 110 KKDVKFGFAWANSMHDLNGQEQKLKVDE 27
+++ +L ++QKL+ ++
Sbjct: 2214 EQEKA---QLLEQKKNLEEEKQKLETEK 2238
Score = 94.0 bits (232), Expect = 3e-16
Identities = 133/615 (21%), Positives = 269/615 (43%), Gaps = 28/615 (4%)
Frame = -1
Query: 2258 ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQ 2079
+LQ + Q +++ K + N +E+K NI S Q+N+E Q ++ +
Sbjct: 2562 DLQNQLKQMTQNRDELQSKSDKLNEEIEEKKNIQNLESSLEQKNKENEDLKQQLNKTQGE 2621
Query: 2078 MHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL--------QDLENQKE 1923
+ A Q + +EL D ++ ++ ++ A ++K + Q LEN+
Sbjct: 2622 LSAQLQQKTQELENLTKEFNDLKQKSEQTIAQNNEEIANLKKNVAERDKKISQLLENEVN 2681
Query: 1922 TVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQM 1743
+ K+L+ +E + S +SE+E N L + +K E EI +L +L M++
Sbjct: 2682 ELKKKLS---DKENENTSLKNTISERENEINN--LKKNVSDK--ENEINQLKNNLTMRET 2734
Query: 1742 ENTLLKDGNEKIYDLCKLLATKSR---EVQGQQEGILKQDINIEDELARTKE----VGRS 1584
E +KD E++ + +++A K + E+ G+ DEL + KE + +
Sbjct: 2735 ELNKMKD--EEVKNAKQIIAQKDKDLEELNGKFNDTNNNLSKANDELKQLKEQIESLNKQ 2792
Query: 1583 ATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVL---GNINSLRNDAQMVQVALEQM 1413
MK N+ +++ + L K + L ++ IN L N+ + +Q L+Q
Sbjct: 2793 IEQMKCSNNLKESEIKQLTSNLQKYKQALKELNDQNKQKDSQINQLNNEMKELQQTLKQT 2852
Query: 1412 QDTKSELFAEAEIRAQEVLRLQAE--VDAIQHILIELKRKNQTLQDESQRNAK----ELW 1251
Q+ E + + + QE L + + + + + ELK+K Q + D+ Q N K EL
Sbjct: 2853 QEQLKETQDQLK-QTQETLATKEKEFAKSAEDLNNELKKKQQAI-DDLQNNLKQKDAELT 2910
Query: 1250 NAK----ARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVE 1083
+ K A+ N E++ SL+ E+ K +E +SE ++ E +
Sbjct: 2911 DTKQKLEAKTNEFNDLKQKAENEIASLRKEIEQLKAKLANTSKELEASKSESDLQKKEND 2970
Query: 1082 NLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENA 903
LK L + +++ L + ++ + + +EK+ + ++ E
Sbjct: 2971 KLKVNLAK-------IAEMYKTLKSESENNSAKSNDKIKQMQEKIQNLE-----IQVEKM 3018
Query: 902 KLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNK 723
KL NE L + +++ + E ++ + +S + A+ +E++ + ++ +L K++
Sbjct: 3019 KLANENLTNENKLQKETI-----EMLNKKLLESNKSLTASIKEYETLKREN---NLQKDQ 3070
Query: 722 CTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLK 543
T+L QVQKL++ F +E ++ +KL E+ L+ + LK
Sbjct: 3071 ITKLTSQVQKLTQD---FTQLKKEKAEVDSKLNELLDLLAQ----------KDKEIERLK 3117
Query: 542 KENTRLRSEMKGELT 498
EN +L +E+ ++T
Sbjct: 3118 SENQKL-NELYQQIT 3131
Score = 92.4 bits (228), Expect = 8e-16
Identities = 138/772 (17%), Positives = 315/772 (40%), Gaps = 91/772 (11%)
Frame = -1
Query: 2300 EVSRLYEEEKQHTIELQENFNALRQKNEDICLK------------IEANNNLLEQKDNII 2157
E+S +++ Q L + FN L+QK+E + E + + + +N +
Sbjct: 2621 ELSAQLQQKTQELENLTKEFNDLKQKSEQTIAQNNEEIANLKKNVAERDKKISQLLENEV 2680
Query: 2156 VELSHKLQENEEQRSAL-------QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLK 1998
EL KL + E + ++L +N++ ++++ + + E +L L + ++N +K
Sbjct: 2681 NELKKKLSDKENENTSLKNTISERENEINNLKKNVSDKENEINQLKNNLTMRETELNKMK 2740
Query: 1997 E------ALSMAVDDRAFME----------------KQLQDLENQKETVSKELALSVSRE 1884
+ +A D+ E +L+ L+ Q E+++K++
Sbjct: 2741 DEEVKNAKQIIAQKDKDLEELNGKFNDTNNNLSKANDELKQLKEQIESLNKQIEQMKCSN 2800
Query: 1883 QKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTL------LKD 1722
S++K L+ + K L +QNKQ + +I +L + +MK+++ TL LK+
Sbjct: 2801 NLKESEIKQLTSNLQKYKQALKELNDQNKQKDSQINQL--NNEMKELQQTLKQTQEQLKE 2858
Query: 1721 GNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAK 1542
+++ + LATK +E E D+N E K+ ++ D++ A+
Sbjct: 2859 TQDQLKQTQETLATKEKEFAKSAE-----DLNNE-----LKKKQQAIDDLQNNLKQKDAE 2908
Query: 1541 VSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQE 1362
++ + L ++ LK++ I SLR + + ++ L +E++++ +E
Sbjct: 2909 LTDTKQKLEAKTNEFNDLKQKAENEIASLRKEIEQLKAKLANTSKELEASKSESDLQKKE 2968
Query: 1361 VLRLQAEVDAIQHILIELKRKNQT----LQDESQRNAKELWNAKARLNNVMSKNINLESQ 1194
+L+ + I + LK +++ D+ ++ +++ N + ++ + N NL ++
Sbjct: 2969 NDKLKVNLAKIAEMYKTLKSESENNSAKSNDKIKQMQEKIQNLEIQVEKMKLANENLTNE 3028
Query: 1193 NRSLKAELHLQAQKAFQ--------------IQEERNVVESEHNVLSSEVENLKSEL--- 1065
N+ K + + +K + ++ E N+ + + L+S+V+ L +
Sbjct: 3029 NKLQKETIEMLNKKLLESNKSLTASIKEYETLKRENNLQKDQITKLTSQVQKLTQDFTQL 3088
Query: 1064 -KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAE--EKLMRILDEL-ICLRNENAKL 897
KE +++ L ++L + E+ L E+ + E +++ + L+E ++++N
Sbjct: 3089 KKEKAEVDSKLNELLDLLAQKDKEIERLKSENQKLNELYQQITKDLEEKEFLIQSQN--- 3145
Query: 896 KNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSG--------- 744
N + + E+KN + + ++ SL + RE E++
Sbjct: 3146 -NRCIDLLNLTEKKNKEIETLQISNDSLNNSLTKSQMELREKSTLLENAKDKITESNRKL 3204
Query: 743 --VDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXX 570
D L + L K S + + + +QT+ +
Sbjct: 3205 ALFDRLSANSSELNLTSSGRGIKKSSSMNLSTDMDSKNKIINQQEQTIIGLEQSLKVSKN 3264
Query: 569 XXIRV-RSLKKE---NTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXX 402
R L+K+ N L++++K + + S +K++N D+ L+
Sbjct: 3265 EVDATKRELQKQLQNNKELQNQIKMTKEQFAKLEAKLQSVVKKLNDKDQRIDSLMSS--- 3321
Query: 401 XXXXXXXKIDTRTSETQEIDTLMDD----NRKYWNRVSHFTKQTQSLQNSVQ 258
D +T +++ + D N K RV T++ QSL++ ++
Sbjct: 3322 ---------DPNNKQTNQLNKQISDLNLENEKLKTRVDIITRENQSLKDDLE 3364
Score = 89.0 bits (219), Expect = 8e-15
Identities = 139/735 (18%), Positives = 295/735 (40%), Gaps = 49/735 (6%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLK----------IEANNNLLEQKDNIIV 2154
++V+ EE KQ + EN ++Q DI K IE + + Q+D I
Sbjct: 1438 QDVATKEEEIKQLKQTVSENEEVIKQLQTDIEQKDAEIQKNKEEIEQHKQTISQRDETIK 1497
Query: 2153 ELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVD 1974
+L +++++++ + N+++ ++ + +EREE +QL N +++ +
Sbjct: 1498 QLQSEIEQHKQTIADKNNEIEQLKN----TISEREETIKQLQ------NEIEQHKQTMAE 1547
Query: 1973 DRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKE---ESTKNQLLIQTEQ 1803
A ++K +++E QK+T+S + ++ K +SE++ E K + + E
Sbjct: 1548 RDAEIQKNKEEIEQQKQTIS-------NNNNEIEQLKKTISERDAEIEQLKKTIAERDES 1600
Query: 1802 NKQLELEIEKLYGSLQMKQMENTLLK----DGNEKIYDLCKLLATKSREVQGQQEGI--- 1644
KQL+ EIE+ ++ + E LK ++ I + L+ E++ ++ I
Sbjct: 1601 IKQLQNEIEQHKQTISQRDAEIEQLKQTVQQRDQTIAEKEDLIKQLQSEIEQHKQTISDK 1660
Query: 1643 ------LKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKE 1482
LKQ +N DE K++ K+ ++ A++ E + K + E
Sbjct: 1661 NNEIEQLKQTVNARDE--AIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQTISQRDE 1718
Query: 1481 EVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLR----LQAEVDAIQHILI 1314
I L+N+ +EQ + T S+ AE E Q V + + + D I+ +
Sbjct: 1719 ----TIKQLQNE-------IEQHKQTISQRDAEIEQLKQTVQQSDQTIAEKEDLIKQLQS 1767
Query: 1313 ELKRKNQTLQD---ESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQ 1143
E+++ QT+ + E Q+N +E+ K + ++ +++ ++ A + +
Sbjct: 1768 EIEQHKQTIAERDAEIQKNKEEIEQQK---QTISQRDESIKQMQSEIEQNKQTIADREKE 1824
Query: 1142 IQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRF 963
I++ + + N + E ++ + + + + E + ++ + +L E
Sbjct: 1825 IEQHKQTIAERDNSIKQLQEEIEQHKQTIAERDAEIQKNKEEIQQKNEAINALTNE---- 1880
Query: 962 AEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRAN 783
EEK ++IL+ L N L N+ N+S ++ ++ + +
Sbjct: 1881 GEEKRLKILE----LEANNENLINKVKELNDSVSDLNLSTENQNSVVKQMTDEIKDLNKQ 1936
Query: 782 QREFQNK--------EEDSSGVDLLKNKCTRLEFQVQKLSEKAE-MFETKSREAQQMANK 630
E + K EE + L N + E ++KL E+ E + TK++ + + N
Sbjct: 1937 IHELEVKSENQQKQIEEKDKEIQSLTNTKAQNEELIKKLQEEVENLTNTKNQNEETIKNL 1996
Query: 629 LEEMQQTLSDMXXXXXXXXXXXIRVRSL---KKENTRLRSEMKGELTPSRSFKHREGSFI 459
E++Q +++SL K EN ++ ++ K I
Sbjct: 1997 QEQVQSLTETKNQNEDLIKKQQEQIQSLTNTKNENEETIKNLQEQVQSLTETKATNEETI 2056
Query: 458 K----EINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFT 291
K E+ E + +T+ + I L ++ + N +
Sbjct: 2057 KKLQGEVQSLTETKATNEEQIKKQQEEIQSLSNTKNENEELIKKLQEEIQNLTNTKTQNE 2116
Query: 290 KQTQSLQNSVQELQQ 246
+Q + LQ +Q LQ+
Sbjct: 2117 EQIKKLQEEIQNLQK 2131
Score = 84.7 bits (208), Expect = 2e-13
Identities = 147/714 (20%), Positives = 302/714 (42%), Gaps = 42/714 (5%)
Frame = -1
Query: 2261 IELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQEN---------EEQRSA 2109
I + +A++Q E+ ++ N + KDN I+ L+ L + +E+
Sbjct: 1044 ITYENESDAMKQIKEENYRRVVENTH----KDNEIIRLTKLLATDKTLKEDKILQEKIMQ 1099
Query: 2108 LQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQ 1929
L+ +Q ++ + + E N + L+D++N LKE + D++A +K+L + + Q
Sbjct: 1100 LEAKVQQMKDFNKETAANLESKNLENYNLQDNINSLKEQIQKQNDEQANHQKELDERDEQ 1159
Query: 1928 KETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLE-LEIEKLYGSLQM 1752
+ KE+ E + + +S+++ + N L E ++E I K G L +
Sbjct: 1160 IAVLQKEIE---KYENRYLEQQEVISQEKLNNSNLKLKLNEAENEIEKSHIVKQPGELYL 1216
Query: 1751 KQMENTLLKDGNE-KIYD-LCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSAT 1578
++ + N+ KI + + K +E++ Q E KQ + E +++E+ R
Sbjct: 1217 SEVPQQISYFENKVKIMNGMITQSNAKIKELESQIEKKNKQIESTEALQKKSRELYRQIR 1276
Query: 1577 DMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKS 1398
D ++ S G V I EM + +K+ +K + +D + + LE ++
Sbjct: 1277 DYEQRLSSLGLTVEQIREMEMTIKNQANIIKAK--------DDDLKQTKEILEYREEQIE 1328
Query: 1397 ELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMS 1218
+ AE+ + L+ + ++ +L + ++N E Q ++ A+
Sbjct: 1329 KFIAESVSIRDAIETLKQRISELEMLLEKKDKENNDKIAEIQEENRQTLEQLAKQLQEAE 1388
Query: 1217 KNIN-LESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVL---SSEVENLKSEL----K 1062
++IN LE + + E+ A+K QI++ N ++S V+ S+ +++LK ++ +
Sbjct: 1389 EDINVLEGNCQVYEQEI---AEKDKQIEQMTNDIKSLEEVINEQSNTIDSLKQDVATKEE 1445
Query: 1061 ESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEE-----KLMRILDELI-CLRNENAK 900
E K L+ E++ ++ D E + EE + + DE I L++E +
Sbjct: 1446 EIKQLKQTVSENEEVIKQLQTDIEQKDAEIQKNKEEIEQHKQTISQRDETIKQLQSEIEQ 1505
Query: 899 LKNEALYEYHDYER-KNVSGSRAEAMSVL---ISKSLGNGRANQREFQ-NKEEDSSGVDL 735
K + ++ E+ KN R E + L I + E Q NKEE
Sbjct: 1506 HKQTIADKNNEIEQLKNTISEREETIKQLQNEIEQHKQTMAERDAEIQKNKEEIEQQKQT 1565
Query: 734 LKNKCTRLEFQVQKLSEK-AEMFETKSREAQ------QMANKLEEMQQTLSDMXXXXXXX 576
+ N +E + +SE+ AE+ + K A+ Q+ N++E+ +QT+S
Sbjct: 1566 ISNNNNEIEQLKKTISERDAEIEQLKKTIAERDESIKQLQNEIEQHKQTISQRDAEIEQL 1625
Query: 575 XXXXIRVRSLKKENTRLRSEMKGELTPSR---SFKHREGSFIKE-INIGDEDDTPLIQXX 408
+ E L +++ E+ + S K+ E +K+ +N DE I+
Sbjct: 1626 KQTVQQRDQTIAEKEDLIKQLQSEIEQHKQTISDKNNEIEQLKQTVNARDE----AIKQL 1681
Query: 407 XXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQ 246
I R +E Q+ ++ ++ +S + + LQN +++ +Q
Sbjct: 1682 QSEIEQHKQTIAERDAEIQKNKEEIEQQKQ---TISQRDETIKQLQNEIEQHKQ 1732
Score = 83.6 bits (205), Expect = 4e-13
Identities = 145/711 (20%), Positives = 300/711 (42%), Gaps = 29/711 (4%)
Frame = -1
Query: 2291 RLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRS 2112
R +++ Q+ ELQ +++ + K+++ L KD I L N +Q +
Sbjct: 3271 RELQKQLQNNKELQNQIKMTKEQFAKLEAKLQSVVKKLNDKDQRIDSLMSS-DPNNKQTN 3329
Query: 2111 ALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL---QD 1941
L + + + +T + + R+ L+DD+ K S + ++ +L +
Sbjct: 3330 QLNKQISDLNLENEKLKTRVDIITRENQSLKDDLESQKSQKSKLDESCNALKTELINKKS 3389
Query: 1940 LENQKETVSKELALSVSREQKLASDLKAL--SEKEESTKNQLLIQTEQNKQLELEI---- 1779
+ +Q + KEL ++ + K S+LKA +E K+ + + ++ + EL++
Sbjct: 3390 IMDQYKEKLKELMEQINLKNKQISELKAEFNGSDDEDRKSYVKVIEQEGEITELKVIIDR 3449
Query: 1778 -EKLYGSLQMKQME-NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 1605
+K G +MK + LK+ N++ + K L T E++ + + + + IE + R
Sbjct: 3450 QKKFVGQQKMKIADLEKNLKESNDEAQKMTKNLQTTIYELEDRCQNLNQ---TIEMKNFR 3506
Query: 1604 TKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVA 1425
+E ++ D+ K K+ IL + M D S K+ ++ I SL+ + V
Sbjct: 3507 LRENEKTIEDLNKEIEFLKGKID-ILSREISMYSDNSS-KDNLISKIVSLQ---KTVSEK 3561
Query: 1424 LEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDE-SQRNAKE--- 1257
EQ+ D K EI ++Q E+D + L+ + + L ++ S NAKE
Sbjct: 3562 DEQLNDAKINSNNSLEIED----KMQQEIDQKNSRIHHLENQMRVLLNKASHENAKEESK 3617
Query: 1256 ----LWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSE 1089
L A +L+N+ + +L+ +N +LK+++ + Q E N++ ++N +E
Sbjct: 3618 VKIDLKKANVKLSNLENDFSSLQEENAALKSKVSKLELVIKEKQSEINIMAQKNNNDINE 3677
Query: 1088 VENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNE 909
+ LKS+L++ + F + Q E+ L L +EL ++E
Sbjct: 3678 ISELKSKLRKQNE---DFTQEKSSAEKQRSEIDQL--------TNDLKAKNNELDDSKSE 3726
Query: 908 NAKLKNEALYEYHDYERKNVS-GSRAEAMSVLISKSLGNGRANQREFQNK--EEDSSGVD 738
LK++ D++ KN S +E +S L K + + E NK + D + +
Sbjct: 3727 IRILKSKINQLQQDFDAKNHSLQKESEKLSQLEEKM----KEKELELLNKSLDNDKAAKE 3782
Query: 737 LLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIR 558
+++ + Q + L E+++ + K ++ +QM L ++ ++ +
Sbjct: 3783 IIE------KLQNENL-EQSKQLKKKEKDIEQMKQILNDLNNEQGELKGKIMTLQNDNEQ 3835
Query: 557 VRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEIN-------IGDEDDTPLIQXXXXX 399
+ +E +L + EL S ++ I E N + E + ++
Sbjct: 3836 ITKTSQEKFKLNEKKSEELV---SMINKLNDEIAEKNKTINGTLLQKEKEITKLKNDLEQ 3892
Query: 398 XXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQ 246
+I SE ++ L DD N ++ + ++ +N +QEL++
Sbjct: 3893 SQITNERITNLESEMMKMKQLNDD---LMNDINRYNEELIEKENELQELRE 3940
Score = 76.6 bits (187), Expect = 4e-11
Identities = 166/856 (19%), Positives = 339/856 (39%), Gaps = 105/856 (12%)
Frame = -1
Query: 2288 LYEEEKQHTIELQENFNALRQKNEDICLKIE----ANNNLLEQ---KDNIIVELSHKLQE 2130
L E + ++ + + +++K +++ +++E AN NL + + I L+ KL E
Sbjct: 2986 LKSESENNSAKSNDKIKQMQEKIQNLEIQVEKMKLANENLTNENKLQKETIEMLNKKLLE 3045
Query: 2129 NEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQ 1950
+ + +A + +++++ + + + + +L Q+ L D LK+ ++A ++ +
Sbjct: 3046 SNKSLTASIKEYETLKRENNLQKDQITKLTSQVQKLTQDFTQLKK-------EKAEVDSK 3098
Query: 1949 LQDLENQKETVSKELALSVSREQKL----ASDLKALSEKEESTKNQ-------LLIQTEQ 1803
L +L + KE+ S QKL K L EKE ++Q L + ++
Sbjct: 3099 LNELLDLLAQKDKEIERLKSENQKLNELYQQITKDLEEKEFLIQSQNNRCIDLLNLTEKK 3158
Query: 1802 NKQLE---LEIEKLYGSLQMKQME----NTLLKDGNEKIYDLCKLLATKSREVQGQQEGI 1644
NK++E + + L SL QME +TLL++ +KI + + LA R E
Sbjct: 3159 NKEIETLQISNDSLNNSLTKSQMELREKSTLLENAKDKITESNRKLALFDRLSANSSE-- 3216
Query: 1643 LKQDINIEDELARTKEVGRS--ATDM---KKVNSDAGAKVSGILEMLLPMKDDVFSLKEE 1479
+N+ K+ +TDM K+ + + G+ + L K++V + K E
Sbjct: 3217 ----LNLTSSGRGIKKSSSMNLSTDMDSKNKIINQQEQTIIGLEQSLKVSKNEVDATKRE 3272
Query: 1478 V---LGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQA------EVDAIQ 1326
+ L N L+N +M + +++ + + + Q + L + + + +
Sbjct: 3273 LQKQLQNNKELQNQIKMTKEQFAKLEAKLQSVVKKLNDKDQRIDSLMSSDPNNKQTNQLN 3332
Query: 1325 HILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAF 1146
+ +L +N+ L+ +E + K L + S+ L+ +LK EL +
Sbjct: 3333 KQISDLNLENEKLKTRVDIITRENQSLKDDLESQKSQKSKLDESCNALKTELINKKSIMD 3392
Query: 1145 QIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDI---E 975
Q +E+ + + N+ + ++ LK+E S D + + + ++ Q E+ L +
Sbjct: 3393 QYKEKLKELMEQINLKNKQISELKAEFNGSDDEDR---KSYVKVIEQEGEITELKVIIDR 3449
Query: 974 SCRFAEEKLMRILDELICLRNEN------AKLKNEALYEYHD--------YERKNVS--- 846
+F ++ M+I D L+ N K +YE D E KN
Sbjct: 3450 QKKFVGQQKMKIADLEKNLKESNDEAQKMTKNLQTTIYELEDRCQNLNQTIEMKNFRLRE 3509
Query: 845 ---------------GSRAEAMSVLISKSLGNGRAN---------QREFQNKEEDSSGVD 738
+ + +S IS N + Q+ K+E +
Sbjct: 3510 NEKTIEDLNKEIEFLKGKIDILSREISMYSDNSSKDNLISKIVSLQKTVSEKDEQLNDAK 3569
Query: 737 LLKNKCTRLEFQVQK-LSEKAEMFETKSREAQQMANKL-----EEMQQTLSDMXXXXXXX 576
+ N +E ++Q+ + +K + + + NK +E + D+
Sbjct: 3570 INSNNSLEIEDKMQQEIDQKNSRIHHLENQMRVLLNKASHENAKEESKVKIDLKKANVKL 3629
Query: 575 XXXXIRVRSLKKENTRLRSEM-KGELTPSRSFKHREGSFIKEINIGDEDD-TPLIQXXXX 402
SL++EN L+S++ K EL K E + + + N D ++ + L
Sbjct: 3630 SNLENDFSSLQEENAALKSKVSKLELVIKE--KQSEINIMAQKNNNDINEISELKSKLRK 3687
Query: 401 XXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXX 222
+ + + EID L +D + N + + + L++ + +LQQ
Sbjct: 3688 QNEDFTQEKSSAEKQRSEIDQLTNDLKAKNNELDDSKSEIRILKSKINQLQQDFDAKNHS 3747
Query: 221 XXXXXXKWGGIDMNSIEKQLKELN------------IHVMQ--LVEHNTRLKKDVKFGFA 84
K ++ EK+L+ LN I +Q +E + +LKK K
Sbjct: 3748 LQKESEKLSQLEEKMKEKELELLNKSLDNDKAAKEIIEKLQNENLEQSKQLKKKEKDIEQ 3807
Query: 83 WANSMHDLNGQEQKLK 36
++DLN ++ +LK
Sbjct: 3808 MKQILNDLNNEQGELK 3823
>gb|EAR95694.2| hypothetical protein TTHERM_00268040 [Tetrahymena thermophila SB210]
Length = 1392
Score = 112 bits (281), Expect = 5e-22
Identities = 137/684 (20%), Positives = 299/684 (43%), Gaps = 64/684 (9%)
Frame = -1
Query: 2303 KEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE 2124
+E++ +++ + +L E + +Q+ E+ L++ +NI+VE + E +
Sbjct: 343 QELNEQHQKSQTEIQKLNEQITSNQQRIEE-----------LQKNENILVEKDKNINEIK 391
Query: 2123 EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQ 1944
EQ SAL ++ + + T+ EE + + L+E + ++ + K++Q
Sbjct: 392 EQLSALNQQIEGFKDIQNKLDTKTEEFEKLEKDFNQQKSELEEKIKSKDEEIENLSKKIQ 451
Query: 1943 DLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQL----LIQTEQNKQLELEI- 1779
D+ Q++ K+L S Q + + L ++ KN++ Q +Q+ QL+ E+
Sbjct: 452 DIVEQQQEKQKQLDDLNSNLQNSNKENEQLKQEINDFKNKINNSNQDQEQQSNQLKAELK 511
Query: 1778 ---EKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELA 1608
E+L S Q + + LKD ++I D L KS+E + ++ + + + +
Sbjct: 512 QTQEQLNDSQQKFEQADKELKDLKQQIEDEKVKLNDKSQESENLKDQLKSANEKLNESQQ 571
Query: 1607 RTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLK---EEVLGNINSLRNDAQM 1437
+ +++ ++ D+K+ N+D V + ++ ++ LK E+V + L + +
Sbjct: 572 KLEQIQKNFDDLKQ-NNDLQKIVDEKQQKCEELERELKELKTQQEQVTAQVQQLNVEKEE 630
Query: 1436 VQVALEQMQDTKSELFAEAEIR-------AQEVLRLQAEVDAIQHILIELKRKNQTLQDE 1278
+Q Q++ K +L + + + QE + E++ ++ + L+++ +Q +
Sbjct: 631 IQTKFNQVEQEKEQLKKQEQEKIDLLSQAKQEKENNEQEINNLKQTIANLEKERTDIQIQ 690
Query: 1277 SQRNAKELWNAKARLNN-----------------VMSKNINLESQNRSLKAELH------ 1167
SQ K+L +AK L N V KN LES+ +K+E+
Sbjct: 691 SQEKDKQLDDAKHTLENLNKEIEQLKNQNQAIGDVNEKNKQLESEITQIKSEIEQKNTEI 750
Query: 1166 --LQAQKAFQIQEER----------NVVESEHNVLSSEVENLKSELKESKDLEGYFLRLF 1023
L ++ +I E++ N + + + LS+E ENLK+E++ ++++ L
Sbjct: 751 QSLNSKNETEISEKKQQLEDHTKQVNQLNEQIHQLSTENENLKNEIQTNQNISQTKL--- 807
Query: 1022 EILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAK---LKNEALYEYHDYERKN 852
L +E +I EE +++ D+ L+ K L+ + L + + ++ N
Sbjct: 808 -TDLNSEIEGFQKEI------EETKLQLDDKNTQLKGLQVKLEALEKQLLEKNEEIQKVN 860
Query: 851 VSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDL------LKNKCTRLEFQV-QK 693
+E I K + + + + K+ + DL LK K L Q+ QK
Sbjct: 861 QQLKESEQKHEAIQKQNEELQNSLKTLEEKDYNQIQNDLNQQVSDLKQKEQDLNKQLDQK 920
Query: 692 LSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEM 513
L E ++ + S E K ++QQT+ + R+++ ++ + +S++
Sbjct: 921 LQEINQIKQQLSNETSDFMKKNVQLQQTIQQLNQTISQYQEQIERIKTDLYQSQQEKSQL 980
Query: 512 KGELT-PSRSFKHREGSFIKEINI 444
+ +L +R +++E K++ I
Sbjct: 981 QSKLNEANREIQNKEDDLNKKVEI 1004
Score = 108 bits (269), Expect = 1e-20
Identities = 142/712 (19%), Positives = 314/712 (44%), Gaps = 43/712 (6%)
Frame = -1
Query: 2252 QENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMH 2073
Q+ FN L ++++ K++ LE N + ++++QE EQ Q ++Q + +
Sbjct: 304 QQQFNKLNSESQENETKLQETKKQLEDLQNELGNKNNQIQELNEQHQKSQTEIQKLNEQI 363
Query: 2072 AVSQTEREEL--NRQLVLLRD-DVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELA 1902
+Q EEL N +++ +D ++N +KE LS A++ + + +D++N+ +T ++E
Sbjct: 364 TSNQQRIEELQKNENILVEKDKNINEIKEQLS-ALNQQI---EGFKDIQNKLDTKTEEFE 419
Query: 1901 LSV----SREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENT 1734
++ +L +K+ E+ E+ ++ EQ ++ + +++ L +LQ EN
Sbjct: 420 KLEKDFNQQKSELEEKIKSKDEEIENLSKKIQDIVEQQQEKQKQLDDLNSNLQNSNKENE 479
Query: 1733 LLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDI-----NIEDELARTKEVGRSATDMK 1569
LK ++I D K S + Q QQ LK ++ + D + ++ + D+K
Sbjct: 480 QLK---QEINDF-KNKINNSNQDQEQQSNQLKAELKQTQEQLNDSQQKFEQADKELKDLK 535
Query: 1568 KVNSDAGAKVSGILEMLLPMKDDVFSLK----------EEVLGNINSLR--NDAQMV--- 1434
+ D K++ + +KD + S E++ N + L+ ND Q +
Sbjct: 536 QQIEDEKVKLNDKSQESENLKDQLKSANEKLNESQQKLEQIQKNFDDLKQNNDLQKIVDE 595
Query: 1433 -QVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRN--- 1266
Q E+++ EL + E +V +L E + IQ +++++ + L+ + Q
Sbjct: 596 KQQKCEELERELKELKTQQEQVTAQVQQLNVEKEEIQTKFNQVEQEKEQLKKQEQEKIDL 655
Query: 1265 ----AKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQ-KAFQIQEERNVVESEHNV 1101
+E N + +NN+ NLE + + ++ +Q+Q K Q+ + ++ +E+
Sbjct: 656 LSQAKQEKENNEQEINNLKQTIANLEKE----RTDIQIQSQEKDKQLDDAKHTLEN---- 707
Query: 1100 LSSEVENLKSE-------LKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMR 942
L+ E+E LK++ +++K LE ++ + ++ E+ SL+ ++ EK +
Sbjct: 708 LNKEIEQLKNQNQAIGDVNEKNKQLESEITQIKSEIEQKNTEIQSLNSKNETEISEKKQQ 767
Query: 941 ILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNK 762
+ D + K N+ + H +N + + IS++ ++ E K
Sbjct: 768 LED--------HTKQVNQLNEQIHQLSTENENLKNEIQTNQNISQTKLTDLNSEIEGFQK 819
Query: 761 EEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXX 582
E + + + L +K T+L+ KL + K+ E Q++ +L+E +Q
Sbjct: 820 EIEETKLQ-LDDKNTQLKGLQVKLEALEKQLLEKNEEIQKVNQQLKESEQ---------- 868
Query: 581 XXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXX 402
+ +++K+N L++ +K + + + ++++ + + L
Sbjct: 869 -------KHEAIQKQNEELQNSLK--TLEEKDYNQIQNDLNQQVSDLKQKEQDL------ 913
Query: 401 XXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQ 246
++D + E +I ++ N S F K+ LQ ++Q+L Q
Sbjct: 914 -----NKQLDQKLQEINQI------KQQLSNETSDFMKKNVQLQQTIQQLNQ 954
Score = 59.7 bits (143), Expect = 5e-06
Identities = 136/726 (18%), Positives = 287/726 (39%), Gaps = 26/726 (3%)
Frame = -1
Query: 2129 NEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQ 1950
++E++ QN+ Q EQ + Q E E Q ++ K + + +D +
Sbjct: 8 DQEKQVEAQNEEQKQEQENN-EQKENESEQAQTDPQISSGSNQKFDIEITDEDNDPEIEN 66
Query: 1949 LQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQ-NKQLELEIEK 1773
Q +E K + +L + + LA +LK E+ +Q + E+ K+ + IEK
Sbjct: 67 NQTIEQMKFK-AYDLKAELKKVGNLAEELKVKFANLETDYDQCKDEKEELEKKYKQSIEK 125
Query: 1772 LYGSLQMKQMENTLLKDGNE----------KIYDLCKLLATKSREVQGQQEGILKQDINI 1623
YG + MK E+ ++ NE +I +L K K + Q+ I + +
Sbjct: 126 -YGEM-MKNYEHQIISLENENNIRIQQLQQQIDELKKQNEEKEQSYLNMQQQIKQDKQSF 183
Query: 1622 EDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDA 1443
+D + +E+ + + K NSD K+ +L EEV+ N +
Sbjct: 184 DDIQNKYEEINKHNQEQFKQNSDQWVKL--------------VNLTEEVIFNFYNSNF-- 227
Query: 1442 QMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNA 1263
+ K ++ ++ I Q Q ++ L E K KN+ + DE+
Sbjct: 228 ---------FTENKDDISSQTHIILQHQQTFQQLIEKYVTFLAEQKEKNEAISDEA---- 274
Query: 1262 KELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVE 1083
N + S+N N + +L QK Q++ N + SE ++++
Sbjct: 275 ---------FNKIKSENGNGVQKTNQRVQDLQ---QKFEAYQQQFNKLNSESQENETKLQ 322
Query: 1082 NLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENA 903
K +L++ ++ G + L QH + + +I+ + ++EL +NEN
Sbjct: 323 ETKKQLEDLQNELGNKNNQIQELNEQH-QKSQTEIQKLNEQITSNQQRIEEL--QKNENI 379
Query: 902 KLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDL-LKN 726
++ + KN++ + E +S L ++ + + Q + K E+ ++
Sbjct: 380 LVEKD----------KNINEIK-EQLSAL-NQQIEGFKDIQNKLDTKTEEFEKLEKDFNQ 427
Query: 725 KCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSL 546
+ + LE +K+ K E E S++ Q + + +E Q+ L D+ +++
Sbjct: 428 QKSELE---EKIKSKDEEIENLSKKIQDIVEQQQEKQKQLDDL----------NSNLQNS 474
Query: 545 KKENTRLRSEM---KGELTPSRSFKHREGSFIK-EINIGDE---DDTPLIQXXXXXXXXX 387
KEN +L+ E+ K ++ S + ++ + +K E+ E D +
Sbjct: 475 NKENEQLKQEINDFKNKINNSNQDQEQQSNQLKAELKQTQEQLNDSQQKFEQADKELKDL 534
Query: 386 XXKIDTR----TSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXX 219
+I+ ++QE + L D + +++ ++ + +Q + +L+Q
Sbjct: 535 KQQIEDEKVKLNDKSQESENLKDQLKSANEKLNESQQKLEQIQKNFDDLKQNNDLQKIVD 594
Query: 218 XXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRL---KKDVKFGFAWANSMHDLNGQE 48
+E++LKEL Q+ +L K++++ F + ++
Sbjct: 595 EKQQ------KCEELERELKELKTQQEQVTAQVQQLNVEKEEIQTKFNQVEQEKEQLKKQ 648
Query: 47 QKLKVD 30
++ K+D
Sbjct: 649 EQEKID 654