BLASTX nr result
ID: Ephedra27_contig00015415
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Ephedra27_contig00015415
(2659 letters)
Database: ./nr
37,332,560 sequences; 13,225,080,153 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|XP_001765725.1| predicted protein [Physcomitrella patens] gi... 785 0.0
ref|XP_002989230.1| hypothetical protein SELMODRAFT_129513 [Sela... 551 e-154
ref|XP_002965996.1| hypothetical protein SELMODRAFT_84321 [Selag... 551 e-154
gb|EFA79656.1| DNA-dependent protein kinase subunit [Polysphondy... 478 e-132
ref|XP_640856.2| DNA-dependent protein kinase subunit [Dictyost... 467 e-128
ref|XP_003286510.1| DNA-dependent protein kinase subunit [Dictyo... 466 e-128
ref|XP_004350354.1| DNA-dependent protein kinase subunit [Dictyo... 463 e-127
ref|XP_006812077.1| PREDICTED: DNA-dependent protein kinase cata... 395 e-107
ref|XP_003728605.1| PREDICTED: DNA-dependent protein kinase cata... 393 e-106
ref|XP_781813.3| PREDICTED: DNA-dependent protein kinase catalyt... 393 e-106
ref|XP_001919588.3| PREDICTED: DNA-dependent protein kinase cata... 390 e-105
ref|XP_002110143.1| hypothetical protein TRIADDRAFT_20924 [Trich... 390 e-105
ref|XP_001626380.1| predicted protein [Nematostella vectensis] g... 379 e-102
ref|XP_002680550.1| DNA dependent protein kinase catalytic subun... 378 e-102
ref|XP_006021277.1| PREDICTED: DNA-dependent protein kinase cata... 376 e-101
ref|NP_989989.1| DNA-dependent protein kinase catalytic subunit ... 376 e-101
sp|Q8QGX4.1|PRKDC_CHICK RecName: Full=DNA-dependent protein kina... 376 e-101
ref|XP_004454094.1| PREDICTED: DNA-dependent protein kinase cata... 374 e-101
ref|XP_006268879.1| PREDICTED: DNA-dependent protein kinase cata... 373 e-100
dbj|BAA19566.1| DNA-PKcs [Mus musculus] gi|3241860|dbj|BAA28875.... 370 2e-99
>ref|XP_001765725.1| predicted protein [Physcomitrella patens] gi|162683151|gb|EDQ69564.1|
predicted protein [Physcomitrella patens]
Length = 4165
Score = 785 bits (2028), Expect = 0.0
Identities = 417/896 (46%), Positives = 588/896 (65%), Gaps = 13/896 (1%)
Frame = -2
Query: 2649 ARGLILQGSYDASQGYMNQYMAAIEGSNKKEKLNFDFFNTLVKLRCLQADRESTIDAFEA 2470
A GL+ G+ +Q Y+N+YM++ + K +L+F F LV+L+CL+A+R+ + A
Sbjct: 3252 ANGLMECGALPVAQSYINRYMSSKFEFSAKHRLDFRNFKALVRLQCLRAERDES--ANNR 3309
Query: 2469 VTMLQQVRDYVTSTARKALYQNQTKWRAGLKMLEGDVTSKLATFSLKSLSENSVSPKEIE 2290
+ LQQ+ Y+ + RK ++ +M + DV +++A +L S S + ++I
Sbjct: 3310 IKKLQQLLVYIETERRKL--SKHPEFLPEFQMEQADVNARVAWATLSSQSGEGATSQDIT 3367
Query: 2289 NCVSLFGSAYAAYSKLF------SEVSSADPFVHDEFFTSRKIAKAYIKFAFFCDELLNC 2128
C +L GSA+ YS SE+++ HD AKA +KF FCDELL
Sbjct: 3368 ACFALLGSAFKTYSTALDNDDPLSEITTGSLSPHDT-------AKALLKFGLFCDELLKL 3420
Query: 2127 TKQTHWNQDLLLKLKKGDVSASLPPSSEYPVLVVRYIMKAIQMDNNLQIQHGIARVLTLL 1948
++Q + G LP +S+ +LVVR+++KA+ +D+ LQ QH +AR+L+L+
Sbjct: 3421 SQQPEERSQMTQHHLFG-----LPQASDLSLLVVRHMLKALALDSTLQAQHAVARLLSLV 3475
Query: 1947 GHYSNTHSEFVHQQNGIPCWLFIAWIPQILAVLEKEEGAVLVSVLEDIAHLYPQALYFPY 1768
G S T +EF + + W+F+AWIPQ+LA +E++ G VL+ VLE IA YPQALYFP+
Sbjct: 3476 GFSSATQNEFERFLDNVSSWVFVAWIPQMLANIEEDSGRVLIKVLESIAKSYPQALYFPF 3535
Query: 1767 NASKSDFGPIGQERTSKISALLNNPLLNGLVHALEDLTYPEQRLQYWLSHIRNCISVGNT 1588
S++DFG IG++RT + LL NPLL GLV ALEDLT+P+QRL+ L I N + ++
Sbjct: 3536 RVSETDFGAIGRQRTQHLKILLRNPLLEGLVRALEDLTFPQQRLKDGLLQILNFLFTNDS 3595
Query: 1587 KDAEATFHQMFEDCLDSEAMSS--RKSGTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKK 1414
+ A+ F+++++DCLD++++ R++G YN KFA+D++ ++K LG+NGSKL+SMD K+
Sbjct: 3596 ERAQLVFNEIYQDCLDTQSLKDPVRQTGEYNLKFARDWASLIVKELGLNGSKLRSMDAKQ 3655
Query: 1413 YAESIKDLAENLAKSQRNLQTGKISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXSDEEF 1234
++ I L E L+K+ ++ KISLGSLSKW+A++D++ R D +
Sbjct: 3656 FSSVISGLFEKLSKN--DISAEKISLGSLSKWLADFDQTKGIER---------VSRDFDK 3704
Query: 1233 NKSFIEIPGHYTGFKKPDPCSHVKLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKG 1054
N+ IEIPG Y G P+ +HV+L+ FDQ L CL SKQRPKIL MRGSDE DYKF+VKG
Sbjct: 3705 NEMQIEIPGQYNGSSIPNLSTHVQLLGFDQVLICLKSKQRPKILTMRGSDENDYKFVVKG 3764
Query: 1053 GEDLRLDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDD 874
GEDLRLDQRIEQLF MN +L+RD CS++KL++RTY+V+P+SK+CG+++F+E+T V+ +
Sbjct: 3765 GEDLRLDQRIEQLFEAMNNVLNRDAACSQRKLAIRTYSVIPVSKKCGLLQFVENTCVLQE 3824
Query: 873 VIRDGLMHKMPSVRHATSKQEKNTPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKK 694
VIRDGL K+ S H K + T LL ++ +Y +W+ KKGG ++ +E Y N+Y+K
Sbjct: 3825 VIRDGLSSKLASRTHEGYKPLQATSETLLKEIQHEYIEWVRKKGGGKSQ-TECYCNLYRK 3883
Query: 693 ASAEDIKKEMEILTSQLPWDALKTGISKLATSAESFLALRSQFTRSLSALSICCYVAGVG 514
E++ ++ L QLPWD L+ G S+L TSAES+LALRSQF RSLS SIC YVAGVG
Sbjct: 3884 VGFEEVSLKLSALQGQLPWDTLRMGFSRLVTSAESYLALRSQFARSLSVTSICGYVAGVG 3943
Query: 513 DRHLSNFLLDTKRGTLIPIDFGYSFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLLR 334
DRHL N L+D + G L+PIDFGYSFGT V+LLPVPEL+PFRLT Q N LLPL AVGLLR
Sbjct: 3944 DRHLGNTLVDMRTGALVPIDFGYSFGTNVLLLPVPELVPFRLTAQLKNFLLPLTAVGLLR 4003
Query: 333 NDMISTLSALHSSRDVLSAVLDVFTNEPLMDWKNEAMRTSSMRKTDKKNVDLESQDFEIN 154
+DM+ ++AL SR ++SAV++VF EPL+DW+ EA++ R D D N
Sbjct: 4004 SDMVRIMTALRGSRGLISAVMEVFVKEPLVDWRQEAVKLQRARARDVSKSTALEADAGAN 4063
Query: 153 TH-----EEQHVALKVENAHRKLNLWNPAEIVVSELHSSVHSGKTYLNNLERIVRG 1
H EE+HV LKVE A KL+LWNPAEI +SEL SVH+ K Y LE IVRG
Sbjct: 4064 HHMAAFSEEEHVQLKVETAQCKLDLWNPAEITISELGFSVHANKPYTRALEEIVRG 4119
>ref|XP_002989230.1| hypothetical protein SELMODRAFT_129513 [Selaginella moellendorffii]
gi|300142973|gb|EFJ09668.1| hypothetical protein
SELMODRAFT_129513 [Selaginella moellendorffii]
Length = 524
Score = 551 bits (1420), Expect = e-154
Identities = 276/508 (54%), Positives = 365/508 (71%)
Frame = -2
Query: 1524 SRKSGTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESIKDLAENLAKSQRNLQTGK 1345
+R++G YN KFA+DYSK V+KALG +GSKL MDEKK+A +I + +L K+ ++L GK
Sbjct: 5 TRQAGEYNVKFARDYSKPVVKALGEDGSKLLQMDEKKFATAIAGVLTSLQKAIKDLPGGK 64
Query: 1344 ISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXSDEEFNKSFIEIPGHYTGFKKPDPCSHV 1165
+SL S SKWMA +D+ + IEIPG Y G + PD SH+
Sbjct: 65 LSLASFSKWMANFDQP---------------RGRGSSSDDLIEIPGQYDGLQCPDVSSHI 109
Query: 1164 KLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLRLDQRIEQLFGVMNEILSR 985
L+ FD+TL LSSKQRPKIL MRGSDEK+YKF+VKGGEDLRLDQRIEQLF MN +L
Sbjct: 110 TLVGFDETLIGLSSKQRPKILTMRGSDEKEYKFIVKGGEDLRLDQRIEQLFAKMNSVLRE 169
Query: 984 DIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDGLMHKMPSVRHATSKQEKN 805
D C++++LS+RTYAV+P+S+QCG+++F+++T V+DDVI+DG+ ++ + + K
Sbjct: 170 DGACAKRELSMRTYAVIPVSQQCGLLQFVDNTCVLDDVIKDGVAQQLAAAKR------KE 223
Query: 804 TPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAEDIKKEMEILTSQLPWDALK 625
LL LR QY W+ KKGGS + + + Y N+Y K A +++ M L +Q+PWDALK
Sbjct: 224 KAGDLLVELRNQYHQWVEKKGGSKS-VHDCYKNLYTKVKAGEMEARMNALVAQVPWDALK 282
Query: 624 TGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDFGY 445
TG+ K +SAESFLA+RSQF RSLS +SIC Y+AGVGDRHL+N L+D + G+L+PIDFGY
Sbjct: 283 TGLYKRTSSAESFLAMRSQFARSLSVMSICGYIAGVGDRHLANTLIDMQTGSLVPIDFGY 342
Query: 444 SFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLLRNDMISTLSALHSSRDVLSAVLDV 265
SFGTGVILLPVPELIPFRLTPQ TNVLLPLD++GLL+NDM+ LSALH SR ++ AV+DV
Sbjct: 343 SFGTGVILLPVPELIPFRLTPQLTNVLLPLDSLGLLKNDMVRVLSALHKSRQMICAVMDV 402
Query: 264 FTNEPLMDWKNEAMRTSSMRKTDKKNVDLESQDFEINTHEEQHVALKVENAHRKLNLWNP 85
F EPL+DWK EA RT+S+R +++ +HE+QHV LK+ENA RKL+LWNP
Sbjct: 403 FVREPLVDWKKEAARTASIRGGEEE------------SHEQQHVELKIENAQRKLDLWNP 450
Query: 84 AEIVVSELHSSVHSGKTYLNNLERIVRG 1
A + + EL SSVH+G +++ +E V G
Sbjct: 451 AHVTLGELQSSVHAGTPWMHAIEAAVLG 478
>ref|XP_002965996.1| hypothetical protein SELMODRAFT_84321 [Selaginella moellendorffii]
gi|300166810|gb|EFJ33416.1| hypothetical protein
SELMODRAFT_84321 [Selaginella moellendorffii]
Length = 524
Score = 551 bits (1419), Expect = e-154
Identities = 276/508 (54%), Positives = 364/508 (71%)
Frame = -2
Query: 1524 SRKSGTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESIKDLAENLAKSQRNLQTGK 1345
+R++G YN KFA+DYSK V+KALG +GSKL MDEKK+A +I + +L K+ ++L GK
Sbjct: 5 TRQAGEYNVKFARDYSKPVVKALGEDGSKLLQMDEKKFATAIAGVLTSLQKAIKDLPGGK 64
Query: 1344 ISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXSDEEFNKSFIEIPGHYTGFKKPDPCSHV 1165
+SL S SKWMA +D+ + IEIPG Y G + PD SH+
Sbjct: 65 LSLASFSKWMANFDQP---------------RGRGSSSDDLIEIPGQYDGLQCPDVSSHI 109
Query: 1164 KLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLRLDQRIEQLFGVMNEILSR 985
L+ FD+TL LSSKQRPKIL MRGSDEK+YKF+VKGGEDLRLDQRIEQLF MN +L
Sbjct: 110 TLVGFDETLISLSSKQRPKILTMRGSDEKEYKFIVKGGEDLRLDQRIEQLFAKMNSVLRE 169
Query: 984 DIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDGLMHKMPSVRHATSKQEKN 805
D C++++LS+RTYAV+P+S+QCG+++F+++T V+DDVI+DG+ ++ + + K
Sbjct: 170 DGACAKRELSMRTYAVIPVSQQCGLLQFVDNTCVLDDVIKDGVAQQLAAAKR------KE 223
Query: 804 TPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAEDIKKEMEILTSQLPWDALK 625
LL LR QY W+ KKGGS + + + Y N+Y K A +++ M L +Q+PWDALK
Sbjct: 224 KAGDLLVELRNQYHQWVEKKGGSKS-VHDCYKNLYTKVKAGEMEARMNALVAQVPWDALK 282
Query: 624 TGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDFGY 445
TG+ K +SAESFLA+RSQF RSLS +SIC Y+AGVGDRHL+N L+D + G+L+PIDFGY
Sbjct: 283 TGLYKRTSSAESFLAMRSQFARSLSVMSICGYIAGVGDRHLANTLIDMQTGSLVPIDFGY 342
Query: 444 SFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLLRNDMISTLSALHSSRDVLSAVLDV 265
SFGTGVILLPVPELIPFRLTPQ TNVLLPLD++GLL+NDM+ LSALH SR ++ AV+DV
Sbjct: 343 SFGTGVILLPVPELIPFRLTPQLTNVLLPLDSLGLLKNDMVRVLSALHKSRQMICAVMDV 402
Query: 264 FTNEPLMDWKNEAMRTSSMRKTDKKNVDLESQDFEINTHEEQHVALKVENAHRKLNLWNP 85
F EPL+DWK EA RT+S+R +++ +HE+QHV LK+ENA RKL+LWNP
Sbjct: 403 FVREPLVDWKKEAARTASIRGGEEE------------SHEQQHVELKIENAQRKLDLWNP 450
Query: 84 AEIVVSELHSSVHSGKTYLNNLERIVRG 1
A + + EL SSVH+G ++ +E V G
Sbjct: 451 AHVTLGELQSSVHAGTPWMPAIEAAVLG 478
>gb|EFA79656.1| DNA-dependent protein kinase subunit [Polysphondylium pallidum PN500]
Length = 4074
Score = 478 bits (1231), Expect = e-132
Identities = 298/905 (32%), Positives = 466/905 (51%), Gaps = 19/905 (2%)
Frame = -2
Query: 2658 YEAARGLILQGSYDASQGYMNQYMAAIEGSNKKEKLNFDFFNTLVKLRCLQADRESTIDA 2479
++ ++G G+ S+ Y + + + + + L F ++L+K+ CL+A +T
Sbjct: 3196 HQMSKGARKLGNIIVSEAYFRLAVKSYPKTREND-LAFPLVSSLIKIYCLKAKNSTT--Q 3252
Query: 2478 FEAVTMLQQVRDYVTSTARKALYQNQTKWRAGLKMLEGDVT-----------SKLATFSL 2332
E + + +V S + + +N K L G++ S L +L
Sbjct: 3253 VETLDRFIKALKFVESKSDEDSIKNNPDNLQRYKRLHGNIQWEIYQLDQKLGSNLVMENL 3312
Query: 2331 KSLSENSVSPKEIENCVS-LFGSAYAAYSKLFSEVSSADPFVHDEFFTSRKIAKAYIKFA 2155
K S+S S LF AY +YS+ S +D + K AY++F
Sbjct: 3313 KKNGLTSLSSLPTTRLSSELFSLAYQSYSQSIQLYDSNSNNNND----THKSKSAYLQFG 3368
Query: 2154 FFCDELLNCTKQTHWNQDLLLKLKKGDVSASLPPSSEYPVLVVRYIMKAIQMDNNLQIQH 1975
FCD L ++GD S S+ V VV IM AI+ + I+
Sbjct: 3369 NFCDTELQ---------------RRGDQSED---SNRLAVSVVNSIMNAIKQEIPGAIEK 3410
Query: 1974 GIARVLTLLGHYSNTHSEFVHQQNGIPCWLFIAWIPQILAVLEKEEGAVLVSVLEDIAHL 1795
R+L ++ Y EFV + IPCW+FI W Q+ L+ +G ++ +L++IA
Sbjct: 3411 -FPRLLEIISQYEKAAKEFVERTKQIPCWMFIRWQSQMFPYLDTPQGPYILPILQEIASN 3469
Query: 1794 YPQALYFPYNASKSDFGPIGQERTSKISALLNNPLLNGLVHALEDLTYPEQRLQYWLSHI 1615
YPQA+YFP+ S FGP ++ T+K+ L NPL++ L+ E LT+PE R + ++ +
Sbjct: 3470 YPQAIYFPFKISSEQFGPTAKKLTAKLEQTLKNPLIDTLISEFERLTHPEHRFKDYMETV 3529
Query: 1614 RNCISVG--NTKDAEATFHQMFEDCLDSEAMSSRKSGTYNEKFAKDYSKKVLKALGMNGS 1441
+ + NT + + +++ DC + + G YN KFAK++ + +GS
Sbjct: 3530 KTMMKSTPINTSEIQKLGVEIYNDCFNPHTVR----GDYNLKFAKEWDHHYSQHFSKDGS 3585
Query: 1440 KLQSMDEKKYAESIKDLAENLAKSQRNLQTGKISLGSLSKWMAEYDESGVFVRQVAXXXX 1261
KL MD KK E + D++ +AK+ + T + L S W+ E+D S
Sbjct: 3586 KLAKMDVKKLVELVADMSGKMAKTMKPSSTATMKLKDFSNWLVEFDRSNQLTE------- 3638
Query: 1260 XXXXSDEEFNKSFIEIPGHYTGFKKPDPCSHVKLISFDQTLTCLSSKQRPKILKMRGSDE 1081
IE+PG Y G KP P H+K+ SFD L + S ++PK +K+ GSDE
Sbjct: 3639 -------------IELPGQYHGTSKPQPEIHIKISSFDPNLLVMGSLRKPKRIKIHGSDE 3685
Query: 1080 KDYKFLVKGGEDLRLDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGVIEF 901
+DY FL+KGGEDLRLDQRI+QLF VMNEIL RD S++ L ++TY VVP++ + G+IE+
Sbjct: 3686 QDYPFLIKGGEDLRLDQRIQQLFFVMNEILKRDPATSKRGLHIKTYQVVPMTGKVGIIEW 3745
Query: 900 IEDTSVIDDVIRDGL-MHKMPSVRHATSKQEKNTPAGLLSSLRTQYQDWILKKGG----S 736
+ DT + ++I D + +H+ + + N + + + + +WI G +
Sbjct: 3746 LNDTKPLKEIIEDQMAVHQ--------NVERSNVSLSRMEAYKI-HNEWINSFGKYIKMA 3796
Query: 735 SAKLSESYTNMYKKASAEDIKKEMEILTSQLPWDALKTGISKLATSAESFLALRSQFTRS 556
+ Y M+ + D K+ E ++P + L+ GI +++S ES+L +R+ F RS
Sbjct: 3797 NPPAGPLYQQMFMHSDRADAIKKQEKQHDKVPANLLQNGIWAISSSPESYLFIRNSFARS 3856
Query: 555 LSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDFGYSFGTGVILLPVPELIPFRLTPQF 376
L+ SIC Y+ G+GDRHL NFL+ K G LI IDFG++FGT LP+PEL+PFRLT QF
Sbjct: 3857 LATFSICSYIIGIGDRHLENFLISQKDGILIGIDFGHAFGTATQFLPIPELMPFRLTRQF 3916
Query: 375 TNVLLPLDAVGLLRNDMISTLSALHSSRDVLSAVLDVFTNEPLMDWKNEAMRTSSMRKTD 196
T+ L+PLD+VGLL ++M TL+A+ +++D L + +DVF EPL+DW A R +
Sbjct: 3917 TSFLMPLDSVGLLSHNMTHTLTAIQNNKDFLLSTMDVFVKEPLIDWIKLASRLGKEQGKG 3976
Query: 195 KKNVDLESQDFEINTHEEQHVALKVENAHRKLNLWNPAEIVVSELHSSVHSGKTYLNNLE 16
K+V E KV+ A RKL WNPA I EL +SVH G+ Y +++
Sbjct: 3977 HKSV------------ESWFPKEKVDIARRKLERWNPAYITSEELANSVHKGQIYEKSIQ 4024
Query: 15 RIVRG 1
+V+G
Sbjct: 4025 NVVKG 4029
>ref|XP_640856.2| DNA-dependent protein kinase subunit [Dictyostelium discoideum AX4]
gi|122086252|sp|Q54UC0.2|PRKDC_DICDI RecName:
Full=DNA-dependent protein kinase catalytic subunit;
Short=DNA-PK catalytic subunit; Short=DNA-PKcs
gi|90970659|gb|EAL66880.2| DNA-dependent protein kinase
subunit [Dictyostelium discoideum AX4]
Length = 4299
Score = 467 bits (1202), Expect = e-128
Identities = 283/796 (35%), Positives = 428/796 (53%), Gaps = 12/796 (1%)
Frame = -2
Query: 2352 KLATFSLKSLSENSVSPKEIENCVSLFGSAYAAYSKLFSEVSSADPFVHDEFFTSR-KIA 2176
KL S L+ S SP +S S Y++ S SS+ P + +E + K
Sbjct: 3524 KLHQKSTNLLNTTSSSPSL---SISSSSSPYSSTS------SSSQPKLSNEILIEKTKTK 3574
Query: 2175 KAYIKFAFFCDELLNC-----TKQTHWNQDLLLKLKKGDVSASLPPSSEYPVLVVRYIMK 2011
A++KFA FCD +L T T +N++++ VS E P V ++
Sbjct: 3575 SAHLKFANFCDNILKDKISQQTTPTQFNEEVIDLATSVIVSTLEAIKEEIPGSVDKFPR- 3633
Query: 2010 AIQMDNNLQIQHGIARVLTLLGHYSNTHSEFVHQQNGIPCWLFIAWIPQILAVLEKEEGA 1831
+ +LT YS EF + + IPCW+FI WI Q+ L+ +G
Sbjct: 3634 -------------LLEILTQFEQYSVIAREFKSRVSTIPCWMFIRWISQMFPYLDLPQGP 3680
Query: 1830 VLVSVLEDIAHLYPQALYFPYNASKSDFGPIGQERTSKISALLNNPLLNGLVHALEDLTY 1651
+++ +L +IA YPQA+YFP+ S FGP+ ++ ++ + L NPLL+ LV + LT+
Sbjct: 3681 LILPILLEIAKWYPQAIYFPFKISSEQFGPLAKKISAPLEKELINPLLDTLVIEFQRLTH 3740
Query: 1650 PEQRLQYWLSHIRNCISVGNTKDAEATFHQMFEDCLDSEAMSSRKSGTYNEKFAKDYSKK 1471
PE R + ++ +++ I KD A ++ + D S SG YN KFAK++
Sbjct: 3741 PEHRFKDYMEEMKSLIKA-TPKDLNA-IAKLNNEIYDDSFNPSTVSGDYNLKFAKEHEAS 3798
Query: 1470 VLKALGMNGSKLQSMDEKKYAESIKDLAENLAKSQRNLQTGKISLGSLSKWMAEYDESGV 1291
L G + +KL MD+KK+ E +++ N+ K+ + T + L S W+A++D S
Sbjct: 3799 YLSNFGKDSTKLARMDQKKFLEIFAEMSGNMNKNMKPNSTASMKLKDFSGWLADFDRSNY 3858
Query: 1290 FVRQVAXXXXXXXXSDEEFNKSFIEIPGHYTGFKKPDPCSHVKLISFDQTLTCLSSKQRP 1111
+EIPG Y G KP P +HV + SFD + + S ++P
Sbjct: 3859 QTSHQ------------------MEIPGQYDGIGKPQPETHVTISSFDTNVLVMGSLRKP 3900
Query: 1110 KILKMRGSDEKDYKFLVKGGEDLRLDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVP 931
K +K+ G+DE DY FL+KGGEDLRLDQRI+QLFG+MNEIL RD C+++ L++ TY VVP
Sbjct: 3901 KRVKIHGNDELDYPFLIKGGEDLRLDQRIQQLFGIMNEILKRDTACNKRSLNVTTYQVVP 3960
Query: 930 ISKQCGVIEFIEDTSVIDDVIRDGLMHKMPSVRHATSKQEKNTPAGLLSSLRTQYQDWI- 754
++ + G+IE++ DT + +++ + L H++ + R N L S + + DWI
Sbjct: 3961 MTSKVGIIEWLNDTKPLREILEEQLAHQLKTPR-------SNVSISKLESTK-YHNDWIN 4012
Query: 753 --LKKGGSSAKLSESYTNMYKKASAEDIKKEMEILTSQLPWDALKTGISKLATSAESFLA 580
K ++ + Y M+ A+ +D K++E S++P + L+ GI L++S ES+L
Sbjct: 4013 SFAKYLKPNSPVGPLYQQMFIHATRDDCAKKLEKQHSKVPENLLQNGIWSLSSSPESYLF 4072
Query: 579 LRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDFGYSFGTGVILLPVPELI 400
+R+ F RSL++ S+C YV G+GDRHL NFL+ + G LI IDFG++FGT LP+PEL+
Sbjct: 4073 IRNSFARSLASFSVCSYVIGIGDRHLENFLISQRDGRLIGIDFGHAFGTATQFLPIPELM 4132
Query: 399 PFRLTPQFTNVLLPLDAVGLLRNDMISTLSALHSSRDVLSAVLDVFTNEPLMDWKNEAMR 220
PFRLT QFT+ L PLD+VGLL ++M TL+AL + +++L +DVF EPL+DW A R
Sbjct: 4133 PFRLTRQFTSFLRPLDSVGLLNHNMTYTLTALQNQKEILLTTMDVFVKEPLLDWSKLATR 4192
Query: 219 ---TSSMRKTDKKNVDLESQDFEINTHEEQHVALKVENAHRKLNLWNPAEIVVSELHSSV 49
D KNV Q K++ A +KL L NPA I + EL SV
Sbjct: 4193 LVKEQGKHPKDTKNVWFPKQ--------------KIQIAKKKLELVNPAYITLEELSGSV 4238
Query: 48 HSGKTYLNNLERIVRG 1
HSG Y L I++G
Sbjct: 4239 HSGLPYEKALSEIIKG 4254
>ref|XP_003286510.1| DNA-dependent protein kinase subunit [Dictyostelium purpureum]
gi|325083491|gb|EGC36942.1| DNA-dependent protein kinase
subunit [Dictyostelium purpureum]
Length = 4168
Score = 466 bits (1198), Expect = e-128
Identities = 270/744 (36%), Positives = 415/744 (55%), Gaps = 16/744 (2%)
Frame = -2
Query: 2184 KIAKAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKGDVSASLPPSSEYPVLVVRYIMKAI 2005
KI A++KFA FCD +L Q++ Q + + ++ +L V++ ++AI
Sbjct: 3444 KIKSAHLKFANFCDNILKDKLQSNNGQ-----INEETLNLALT--------VIKSTLEAI 3490
Query: 2004 --QMDNNLQIQHGIARVLTLLGHYSNTHSEFVHQQNGIPCWLFIAWIPQILAVLEKEEGA 1831
++ ++ + +LT Y + EF + IPCW+FI WI Q+ L+ +G
Sbjct: 3491 REELPGSIDKFPRLLEILTQFEQYQQVNKEFTEHVSNIPCWMFIRWISQMFPYLDLPQGP 3550
Query: 1830 VLVSVLEDIAHLYPQALYFPYNASKSDFGPIGQERTSKISALLNNPLLNGLVHALEDLTY 1651
+++ +L DIA YPQA+YFPY S FGP+ ++ + ++ L++PLL+ LV LT+
Sbjct: 3551 LILPLLLDIAKYYPQAIYFPYKISSEQFGPMAKKLSVQLEKELSDPLLDRLVIEFARLTH 3610
Query: 1650 PEQRLQYWLSHIRNCISVGNTKDAEATF---HQMFEDCLDSEAMSSRKSGTYNEKFAKDY 1480
PE R + ++ +++ I TKD A ++++D + + +S G YN KFAK++
Sbjct: 3611 PEHRFKDFMEEMKSLIK-SPTKDISAISILNSEIYDDSFNPKTVS----GDYNIKFAKEW 3665
Query: 1479 SKKVLKALGMNGSKLQSMDEKKYAESIKDLAENLAKSQRNLQTGKISLGSLSKWMAEYDE 1300
K LK G + + L MD+KK+ E +++ + K+ R T + L S W+ E+D
Sbjct: 3666 EDKYLKYYGKDATILSRMDQKKFLEHFAEMSSEMNKNMRPTSTATMKLKDFSYWLTEFDR 3725
Query: 1299 SGVFVRQVAXXXXXXXXSDEEFNKSFIEIPGHYTGFKKPDPCSHVKLISFDQTLTCLSSK 1120
S + +EIPG Y GF KP P +HV + SFD + + S
Sbjct: 3726 SNYPTSKQ------------------LEIPGQYNGFGKPQPETHVTISSFDSNILVMGSL 3767
Query: 1119 QRPKILKMRGSDEKDYKFLVKGGEDLRLDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYA 940
++PK +K+ G+DE+DY FL+KGGEDLRLDQRI+QLF +MNEIL RD C+++ L + TY
Sbjct: 3768 RKPKRIKIHGNDERDYPFLIKGGEDLRLDQRIQQLFMIMNEILKRDNSCNKRGLKVTTYQ 3827
Query: 939 VVPISKQCGVIEFIEDTSVIDDVIRD--GLMHKMPSVRHATSKQEKNTPAGLLSSLRTQY 766
V+P++ + G+IE+I DT + +++ D + K P + SK E +
Sbjct: 3828 VIPMTSKVGIIEWINDTRPLREILEDQIAIQTKTPRSNVSISKLEATNI----------H 3877
Query: 765 QDWILKKGGSSAKLSES------YTNMYKKASAEDIKKEMEILTSQLPWDALKTGISKLA 604
WI S AK S+ Y M+ A+ ++ K+ E +++P + L+ GI L+
Sbjct: 3878 NTWIQ----SFAKYSKINSPGPLYQQMFIHANRDNAVKKFEKQIAKVPENLLQNGIWALS 3933
Query: 603 TSAESFLALRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDFGYSFGTGVI 424
+S ES+L +R+ F RSL+ S+C YV G+GDRHL NFL+ + GTLI IDFG++FGT
Sbjct: 3934 SSPESYLFIRNSFARSLATFSVCSYVIGIGDRHLENFLISQRDGTLIGIDFGHAFGTATQ 3993
Query: 423 LLPVPELIPFRLTPQFTNVLLPLDAVGLLRNDMISTLSALHSSRDVLSAVLDVFTNEPLM 244
LP+PEL+PFRLT QFT+ L PLD+VGLL ++M +LSAL S +D+L +DVF EPL+
Sbjct: 3994 FLPIPELMPFRLTRQFTSFLRPLDSVGLLNHNMTYSLSALQSHKDILLTTMDVFVKEPLL 4053
Query: 243 DWK---NEAMRTSSMRKTDKKNVDLESQDFEINTHEEQHVALKVENAHRKLNLWNPAEIV 73
DW N ++ D KNV Q K+ A +KL+L+NPA I
Sbjct: 4054 DWSKLANRLVKEQGKHPKDTKNVWFPKQ--------------KIHIAKKKLDLYNPAYIT 4099
Query: 72 VSELHSSVHSGKTYLNNLERIVRG 1
+ EL +SVHS Y NL+ I++G
Sbjct: 4100 LEELSASVHSNSPYEKNLQEIIKG 4123
>ref|XP_004350354.1| DNA-dependent protein kinase subunit [Dictyostelium fasciculatum]
gi|328865264|gb|EGG13650.1| DNA-dependent protein kinase
subunit [Dictyostelium fasciculatum]
Length = 3111
Score = 463 bits (1192), Expect = e-127
Identities = 305/911 (33%), Positives = 472/911 (51%), Gaps = 25/911 (2%)
Frame = -2
Query: 2658 YEAARGLILQGSYDASQGYMNQYMAAIEGSNKKEKLNFDFFNTLVKLRCLQADREST--- 2488
++ ++G G+ S+ Y + + K+ L F ++L+K+ CL+A ST
Sbjct: 2230 HQMSKGARKLGNIIVSESYFRLAVKSYP-KTKENDLAFPLVSSLIKIYCLKAKNSSTPQE 2288
Query: 2487 -IDAFEAVTMLQQVRDYVTSTARKALYQNQTKWRA-------GLKMLEGDVTSKLATFSL 2332
+D F V L+ V K NQ K+ L LEG + + + SL
Sbjct: 2289 CLDRF--VKALKFVVSKSNEETIKQSIDNQQKYERLHGDILWELYQLEGQLGADVVQDSL 2346
Query: 2331 K--SLSENSVSPKEIENCVS-LFGSAYAAYSKLFSEVSSADPFVHDEFFTSRKIAK-AYI 2164
K S+S S+S S LF AY Y+ + ++ ++K AY+
Sbjct: 2347 KKNSMSIPSLSLAPAAKVSSELFNMAYRCYNDSIQLHTKQQQ-------SNNSVSKGAYL 2399
Query: 2163 KFAFFCDELLNCTKQTHWNQDLLLKLKKGDVSASLPPSSEYPVLVVRYIMKAIQMDNNLQ 1984
+FA FCD +L ++T+ N+ K D ++ L S VV + AI+ +
Sbjct: 2400 QFANFCDNVL--AQRTNANE-------KSDEASVLASS------VVNAALTAIKEEIPGA 2444
Query: 1983 IQHGIARVLTLLGHYSNTHSEFVHQQNGIPCWLFIAWIPQILAVLEKEEGAVLVSVLEDI 1804
I+ R+L ++ Y +T ++F IPCW+FI W+ QI L+ +G +++S+L I
Sbjct: 2445 IEK-FPRLLEIISQYESTANDFKENIKTIPCWMFIRWMSQIFPYLDLPQGPLVISILVKI 2503
Query: 1803 AHLYPQALYFPYNASKSDFGPIGQERTSKISALLNNPLLNGLVHALEDLTYPEQRLQYWL 1624
A YPQA+YFPY S FG IGQ+ + + +L + LL+ LE LT+PE R + ++
Sbjct: 2504 AQYYPQAIYFPYKISSEQFGRIGQKVSQPLDLILKDSLLDTFTLELERLTHPEHRFKDYM 2563
Query: 1623 SHIRNCISVG--NTKDAEATFHQMFEDCLDSEAMSSRKSGTYNEKFAKDYSKKVLKALGM 1450
++ + +T +++ DC + + +S G YN+KF+K++ + G+
Sbjct: 2564 ETVKQILKQTPIDTSSLVKLNTEIYNDCFNHKTVS----GDYNKKFSKEWEAIYIGHFGI 2619
Query: 1449 NGSKLQSMDEKKYAESIKDLAENLAKSQRNLQTGKISLGSLSKWMAEYDESGVFVRQVAX 1270
+GSKL MD +K+ E + D+ + K+ + T + L S W+AE+D+S
Sbjct: 2620 DGSKLIKMDGRKFVEVVTDMTIKMNKNMKPTSTASMKLKDFSSWLAEFDKSNYL------ 2673
Query: 1269 XXXXXXXSDEEFNKSFIEIPGHYTGFKKPDPCSHVKLISFDQTLTCLSSKQRPKILKMRG 1090
+ IEIPG Y G+ KP P H+K+ SFD + + S ++PK +K+ G
Sbjct: 2674 --------------NNIEIPGQYNGYGKPQPELHIKVSSFDANILVMGSLRKPKRVKIHG 2719
Query: 1089 SDEKDYKFLVKGGEDLRLDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGV 910
SDE++Y FLVKGGEDLRLDQR++QLF VMN+I+++D S++ L + TY VVP++ + G+
Sbjct: 2720 SDEQNYPFLVKGGEDLRLDQRVQQLFHVMNDIMAKDTATSQRNLKIATYHVVPMTSKVGI 2779
Query: 909 IEFIEDTSVIDDVIRD--GLMHKMPSVRHATSKQEKNTPAGLLSSLRTQYQDWI------ 754
I+++ DT + +++ + + K+ + + S+ E + + DWI
Sbjct: 2780 IQWLLDTKPLKEILEEQMAIHQKVDRSQVSLSRMEASKI----------HSDWIQTFAKY 2829
Query: 753 LKKGGSSAKLSESYTNMYKKASAEDIKKEMEILTSQLPWDALKTGISKLATSAESFLALR 574
LK G Y M+ A+A+D + E +++P L+ GI LA S E++L +R
Sbjct: 2830 LKTSGPPPP-GPLYHQMFIHATAKDAIDKQERQHARIPATLLQKGIWSLAASPEAYLFIR 2888
Query: 573 SQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDFGYSFGTGVILLPVPELIPF 394
S F RSL+ SI YV G+GDRHL NFL+ + G LI IDFG++FGT LP+PEL+PF
Sbjct: 2889 SSFARSLATFSIGSYVIGIGDRHLENFLISQRNGILIGIDFGHAFGTATQFLPIPELMPF 2948
Query: 393 RLTPQFTNVLLPLDAVGLLRNDMISTLSALHSSRDVLSAVLDVFTNEPLMDWKNEAMRTS 214
RLT QFT+ L PLDAVGLL + M TL+AL + +D L + +DVF EPL+DW A R
Sbjct: 2949 RLTRQFTSFLKPLDAVGLLAHTMTHTLNALQNHKDFLLSTMDVFVKEPLIDWVKLASRLG 3008
Query: 213 SMRKTDKKNVDLESQDFEINTHEEQHVALKVENAHRKLNLWNPAEIVVSELHSSVHSGKT 34
DK +E K+ A +KL+ WNPA I E+ SSVH G+
Sbjct: 3009 KEMGADKNT-------------DEWFPKKKIAIAKKKLDRWNPAYITTEEILSSVHKGQI 3055
Query: 33 YLNNLERIVRG 1
Y NL I G
Sbjct: 3056 YEKNLLEITHG 3066
>ref|XP_006812077.1| PREDICTED: DNA-dependent protein kinase catalytic subunit-like
[Saccoglossus kowalevskii]
Length = 2016
Score = 395 bits (1016), Expect = e-107
Identities = 254/743 (34%), Positives = 403/743 (54%), Gaps = 26/743 (3%)
Frame = -2
Query: 2181 IAKAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKGDVSASLPPSSEYPVLVVRYIMKAIQ 2002
+ AY+ A FCD++L KQ N+D G VS S S +P VV +++KA++
Sbjct: 1276 VIDAYVSMATFCDKML---KQQEQNED-------GAVSRS-SKSPSFPRSVVFHLLKALK 1324
Query: 2001 MDNNLQIQHGIARVLTLLGHYSNTHSEFVHQQNGIPCWLFIAWIPQILAVLEKEEGAVLV 1822
+++ IQ R+L ++ Y++T FV + PCW+F+ WI Q+LA+L+K E +
Sbjct: 1325 LNSVEAIQR-FPRLLQIVETYTDTMDTFVELTSETPCWMFLGWIGQMLALLDKVESISVQ 1383
Query: 1821 SVLEDIAHLYPQALYFPYNASKSDF-------GPIGQERTSKISALLNN-PLLNGLVHAL 1666
+L +IA+ YPQAL +P+ S +F G +E+ S+++A+L+N PL+ + AL
Sbjct: 1384 GILLEIANNYPQALVYPFKVSSENFSFENTVTGKRNKEKVSQLAAILDNVPLVMHFICAL 1443
Query: 1665 EDLTYPEQRLQYWLSHI-------RNCISVGNTKDAEATFHQMFE-------DCL---DS 1537
E LT PE + + + RN +V K E + ++F+ D L DS
Sbjct: 1444 EQLTNPEHICKDFTDDVLVPALRARNPTAV--KKAVEGLYTRVFDSKRQSSQDSLFSEDS 1501
Query: 1536 EAMS-SRKSGTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESIKDLAENLAKSQRN 1360
+A++ S G + +KFA D+ K K G G K+ SM +K + ++ + L + ++
Sbjct: 1502 DAVTQSLPFGPFQKKFASDFVKPFQKRFGERGCKILSMQHQKEFMNFRNEVDQLMRKKKM 1561
Query: 1359 LQTGKISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXSDEEFNKSFIEIPGHYTGFKKPD 1180
G +L S W++++ + +EIPG Y G KP
Sbjct: 1562 SAPG--NLREYSPWLSDFQPINY--------------------EKELEIPGQYKGRSKPL 1599
Query: 1179 PCSHVKLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLRLDQRIEQLFGVMN 1000
HVK+ FD+ + +SS ++PK L +RG+DEK++ FLVKGGEDLRLDQRIEQLFG+MN
Sbjct: 1600 LEYHVKIAGFDEKVKVMSSLRKPKRLTIRGNDEKEHNFLVKGGEDLRLDQRIEQLFGIMN 1659
Query: 999 EILSRDIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDGLMHKMPSVRHATS 820
+IL+ D CS++ L L TY V+P++ + G+IE+++ + + + M K +A +
Sbjct: 1660 DILALDAACSQRSLKLVTYEVIPMTPRIGIIEWVDHCLPLKVFLSEA-MTKNERSHYANT 1718
Query: 819 KQEKNTPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAEDIKKEMEILTSQLP 640
+ + +T + D ++K G Y +YK AS +I K+ + L +Q+P
Sbjct: 1719 RLDHHT-----------WVDKMVKHVGDRTSHCVRYGELYKVASRTEILKKFQDLHTQVP 1767
Query: 639 WDALKTGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIP 460
WDAL+ +L++S E+FL LR F S + L IC Y+ G+GDRHLSNF++ G ++
Sbjct: 1768 WDALRRAFQRLSSSPEAFLTLRGHFATSHALLCICQYILGIGDRHLSNFMISLDTGAMVG 1827
Query: 459 IDFGYSFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLLRNDMISTLSALHSSRDVLS 280
IDFG++FG+ V LLPVPEL+P RLT Q N++ P+ GL+ + M+ L AL ++ D+L
Sbjct: 1828 IDFGHAFGSAVELLPVPELMPIRLTRQIVNLMTPMKEDGLILSTMVHGLRALRNNPDLLL 1887
Query: 279 AVLDVFTNEPLMDWKNEAMRTSSMRKTDKKNVDLESQDFEINTHEEQHVALKVENAHRKL 100
+DVF EP +DW+ A K+D ++D N E++ ++ NA RKL
Sbjct: 1888 NTMDVFVKEPHLDWQKRA-------KSDASKYGDAAED--ANEMIERYAKDRINNARRKL 1938
Query: 99 NLWNPAEIVVSELHSSVHSGKTY 31
NP I EL +++ K Y
Sbjct: 1939 QGANPCHITRDELKMNMNIKKHY 1961
>ref|XP_003728605.1| PREDICTED: DNA-dependent protein kinase catalytic subunit-like
isoform 1 [Strongylocentrotus purpuratus]
Length = 1675
Score = 393 bits (1009), Expect = e-106
Identities = 251/736 (34%), Positives = 389/736 (52%), Gaps = 21/736 (2%)
Frame = -2
Query: 2187 RKIAKAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKGDVSASLPPSSEYPVLVVRYIMKA 2008
+ +AKA++ FCD+LL N D L P YP VV ++A
Sbjct: 940 QSMAKAHMALVSFCDQLLRQQDDDDCNPDYL------------PLMEAYPSTVVNSTLQA 987
Query: 2007 IQMDNNLQIQHGIARVLTLLGHYSNTHSEFVHQQNGIPCWLFIAWIPQILAVLEKEEGAV 1828
+ +++ QH R+L L+ Y +T V + + IP W+FI WI Q++A+L+K E
Sbjct: 988 MNLNSPEARQH-FPRLLQLVEKYPDTMQSLVKKASIIPSWMFIGWISQMVALLDKPESLA 1046
Query: 1827 LVSVLEDIAHLYPQALYFPYNASKSDF--GPIGQERTSK-----ISALLNN-PLLNGLVH 1672
+ +L+ IA YPQAL +P+ S DF G +E+ K I +L+ PL+ L
Sbjct: 1047 VQGILKAIAKDYPQALVYPFKISSEDFKLGDKSKEKQRKDAVKEIEDILSTVPLVENLTL 1106
Query: 1671 ALEDLTYPEQRLQYWLSHIRNCIS------VGNTKDAEATFHQMFEDC-LDSEAMSSRKS 1513
AL+ LT+P + W+S I + ++ + ++ + + Q+FE E SS ++
Sbjct: 1107 ALQRLTHPGFIFKDWVSVINSKMNSKKRDHLAIKEEYQQLYQQLFESGGRQGEPSSSSQT 1166
Query: 1512 ---GTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESIKDLAENLAKSQRNLQTGKI 1342
G Y +KF +++ K+ + G +GSKL +MD K +++ +D+ + GK
Sbjct: 1167 VEPGPYWKKFGREWQKRFDSSFGQDGSKLAAMDYKTWSKLRQDICAKMTP-------GKD 1219
Query: 1341 SLGSL---SKWMAEYDESGVFVRQVAXXXXXXXXSDEEFNKSFIEIPGHYTGFKKPDPCS 1171
G+L S W + DE +EIPG Y G KKP P
Sbjct: 1220 DPGNLKEYSPWFTAFQT---------------LRGDE------LEIPGQYDGSKKPLPAY 1258
Query: 1170 HVKLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLRLDQRIEQLFGVMNEIL 991
HVK+ FD+T+ LSS ++PK + +RG+DE DY FLVK GEDLR+DQRIEQLF +MN IL
Sbjct: 1259 HVKIAGFDETVLTLSSLRKPKCITIRGNDEMDYPFLVKVGEDLRMDQRIEQLFCIMNSIL 1318
Query: 990 SRDIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDGLMHKMPSVRHATSKQE 811
++D CS++ L+L TY VVP++ + G++E+++ T+ + D I M H
Sbjct: 1319 AQDAACSQRGLTLTTYQVVPMTPRLGILEWVKRTTTLKDFIT----RSMTEAEHKVYTSR 1374
Query: 810 KNTPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAEDIKKEMEILTSQLPWDA 631
P L ++ W+ K + + + +T YKKA+ + K ++LPWD
Sbjct: 1375 TAGPGALFTT-------WLQKFCQNDGNIIKLFTEAYKKANETETIKAFREREAKLPWDL 1427
Query: 630 LKTGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDF 451
L+ G +L+ S E+FL LR+ F RS + L IC Y+ G+GDRHLSNFL+ + G ++ IDF
Sbjct: 1428 LRRGFMQLSASPEAFLTLRAHFARSHAVLCICQYILGIGDRHLSNFLVSLETGGMVGIDF 1487
Query: 450 GYSFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLLRNDMISTLSALHSSRDVLSAVL 271
G+SFG+ LP+PELIPFRLT Q N++LP+ G+L++ M+ TL AL + ++L +
Sbjct: 1488 GHSFGSATQFLPIPELIPFRLTRQIINLMLPMKIDGVLQSTMVHTLRALRQNHELLVNTM 1547
Query: 270 DVFTNEPLMDWKNEAMRTSSMRKTDKKNVDLESQDFEINTHEEQHVALKVENAHRKLNLW 91
DVF EP +DWK A++ + +K E +I+ + ++ K++ A KL
Sbjct: 1548 DVFVKEPSLDWKCFAVKQADYQKLS------EDSREDISWYPKK----KIKFAEMKLQGV 1597
Query: 90 NPAEIVVSELHSSVHS 43
N I +EL HS
Sbjct: 1598 NSTYITKAELEMGPHS 1613
>ref|XP_781813.3| PREDICTED: DNA-dependent protein kinase catalytic subunit-like
isoform 2 [Strongylocentrotus purpuratus]
Length = 1974
Score = 393 bits (1009), Expect = e-106
Identities = 251/736 (34%), Positives = 389/736 (52%), Gaps = 21/736 (2%)
Frame = -2
Query: 2187 RKIAKAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKGDVSASLPPSSEYPVLVVRYIMKA 2008
+ +AKA++ FCD+LL N D L P YP VV ++A
Sbjct: 1239 QSMAKAHMALVSFCDQLLRQQDDDDCNPDYL------------PLMEAYPSTVVNSTLQA 1286
Query: 2007 IQMDNNLQIQHGIARVLTLLGHYSNTHSEFVHQQNGIPCWLFIAWIPQILAVLEKEEGAV 1828
+ +++ QH R+L L+ Y +T V + + IP W+FI WI Q++A+L+K E
Sbjct: 1287 MNLNSPEARQH-FPRLLQLVEKYPDTMQSLVKKASIIPSWMFIGWISQMVALLDKPESLA 1345
Query: 1827 LVSVLEDIAHLYPQALYFPYNASKSDF--GPIGQERTSK-----ISALLNN-PLLNGLVH 1672
+ +L+ IA YPQAL +P+ S DF G +E+ K I +L+ PL+ L
Sbjct: 1346 VQGILKAIAKDYPQALVYPFKISSEDFKLGDKSKEKQRKDAVKEIEDILSTVPLVENLTL 1405
Query: 1671 ALEDLTYPEQRLQYWLSHIRNCIS------VGNTKDAEATFHQMFEDC-LDSEAMSSRKS 1513
AL+ LT+P + W+S I + ++ + ++ + + Q+FE E SS ++
Sbjct: 1406 ALQRLTHPGFIFKDWVSVINSKMNSKKRDHLAIKEEYQQLYQQLFESGGRQGEPSSSSQT 1465
Query: 1512 ---GTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESIKDLAENLAKSQRNLQTGKI 1342
G Y +KF +++ K+ + G +GSKL +MD K +++ +D+ + GK
Sbjct: 1466 VEPGPYWKKFGREWQKRFDSSFGQDGSKLAAMDYKTWSKLRQDICAKMTP-------GKD 1518
Query: 1341 SLGSL---SKWMAEYDESGVFVRQVAXXXXXXXXSDEEFNKSFIEIPGHYTGFKKPDPCS 1171
G+L S W + DE +EIPG Y G KKP P
Sbjct: 1519 DPGNLKEYSPWFTAFQT---------------LRGDE------LEIPGQYDGSKKPLPAY 1557
Query: 1170 HVKLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLRLDQRIEQLFGVMNEIL 991
HVK+ FD+T+ LSS ++PK + +RG+DE DY FLVK GEDLR+DQRIEQLF +MN IL
Sbjct: 1558 HVKIAGFDETVLTLSSLRKPKCITIRGNDEMDYPFLVKVGEDLRMDQRIEQLFCIMNSIL 1617
Query: 990 SRDIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDGLMHKMPSVRHATSKQE 811
++D CS++ L+L TY VVP++ + G++E+++ T+ + D I M H
Sbjct: 1618 AQDAACSQRGLTLTTYQVVPMTPRLGILEWVKRTTTLKDFIT----RSMTEAEHKVYTSR 1673
Query: 810 KNTPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAEDIKKEMEILTSQLPWDA 631
P L ++ W+ K + + + +T YKKA+ + K ++LPWD
Sbjct: 1674 TAGPGALFTT-------WLQKFCQNDGNIIKLFTEAYKKANETETIKAFREREAKLPWDL 1726
Query: 630 LKTGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDF 451
L+ G +L+ S E+FL LR+ F RS + L IC Y+ G+GDRHLSNFL+ + G ++ IDF
Sbjct: 1727 LRRGFMQLSASPEAFLTLRAHFARSHAVLCICQYILGIGDRHLSNFLVSLETGGMVGIDF 1786
Query: 450 GYSFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLLRNDMISTLSALHSSRDVLSAVL 271
G+SFG+ LP+PELIPFRLT Q N++LP+ G+L++ M+ TL AL + ++L +
Sbjct: 1787 GHSFGSATQFLPIPELIPFRLTRQIINLMLPMKIDGVLQSTMVHTLRALRQNHELLVNTM 1846
Query: 270 DVFTNEPLMDWKNEAMRTSSMRKTDKKNVDLESQDFEINTHEEQHVALKVENAHRKLNLW 91
DVF EP +DWK A++ + +K E +I+ + ++ K++ A KL
Sbjct: 1847 DVFVKEPSLDWKCFAVKQADYQKLS------EDSREDISWYPKK----KIKFAEMKLQGV 1896
Query: 90 NPAEIVVSELHSSVHS 43
N I +EL HS
Sbjct: 1897 NSTYITKAELEMGPHS 1912
>ref|XP_001919588.3| PREDICTED: DNA-dependent protein kinase catalytic subunit [Danio
rerio]
Length = 4112
Score = 390 bits (1003), Expect = e-105
Identities = 247/716 (34%), Positives = 384/716 (53%), Gaps = 9/716 (1%)
Frame = -2
Query: 2181 IAKAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKGDVSASLPPSSEYPVLVVRYIMKAIQ 2002
I +AY+ A FCD L ++Q K+ +S+ L E+ VV+ ++KA++
Sbjct: 3398 IVEAYMTMANFCDRRLRESEQ-----------KEEAISSKLQSLPEH---VVKMMLKALK 3443
Query: 2001 MDNNLQIQHGIARVLTLLGHY-SNTHSEFVHQQNGIPCWLFIAWIPQILAVLEKEEGAVL 1825
+ + + + R+L L+ Y + T V + +PCWL I WI Q++A+L+K + +
Sbjct: 3444 LSSE-EARLKFPRLLQLVEVYPAETLDLMVREVVSVPCWLLIGWISQMMALLDKPQATAV 3502
Query: 1824 VSVLEDIAHLYPQALYFPYNASKSDF-------GPIGQERTSKISALLNNP-LLNGLVHA 1669
V+E+IA YPQAL +PY S ++ G +E K+ +LL+ ++ G V A
Sbjct: 3503 QHVIEEIAECYPQALIYPYMISSENYTFEESASGQRNREFVEKLESLLDKGGVIQGFVDA 3562
Query: 1668 LEDLTYPEQRLQYWLSHIRNCISVGNTKDAEATFHQMFEDCLDSEAMSSRKSGTYNEKFA 1489
L+ L+ PE + W ++N + N + M E D++ S + G+Y KF
Sbjct: 3563 LQQLSNPEMLFKDWWDEVKNQLDKPNLDKKKMKLQYMTELLGDAK---SPRFGSYRRKFI 3619
Query: 1488 KDYSKKVLKALGMNGSKLQSMDEKKYAESIKDLAENLAKSQRNLQTGKISLGSLSKWMAE 1309
+ +SK+V K LG GSKL E++ + + + +S R Q ++ S W++
Sbjct: 3620 QKFSKEVEKLLGAGGSKLY---ERRKDKDFLQQVDRMVQSMRGFQKEPGNMKEYSPWLSS 3676
Query: 1308 YDESGVFVRQVAXXXXXXXXSDEEFNKSFIEIPGHYTGFKKPDPCSHVKLISFDQTLTCL 1129
+ E K+ +E+PG Y G KP P H K+ FD+ + +
Sbjct: 3677 FKA--------------------ETLKNELEVPGQYDGKSKPLPEYHAKITGFDERVKVM 3716
Query: 1128 SSKQRPKILKMRGSDEKDYKFLVKGGEDLRLDQRIEQLFGVMNEILSRDIVCSRKKLSLR 949
+S +RPK + +RG DE+DY FLVKGGEDLR DQRIEQLFGVMN ILS+D CS++ L+LR
Sbjct: 3717 TSIRRPKRIIIRGDDERDYPFLVKGGEDLRQDQRIEQLFGVMNMILSQDTACSQRSLALR 3776
Query: 948 TYAVVPISKQCGVIEFIEDTSVIDDVIRDGLMHKMPSVRHATSKQEKNTPAGLLSSLRTQ 769
TY V+PI+ + G+IE++E+T + D + ++QE+ T ++
Sbjct: 3777 TYQVIPITSRIGLIEWMENTCTLKDFLSS-----------RRTEQEQKT----ITRPNEF 3821
Query: 768 YQDWILKKGGSSAKLSESYTNMYKKASAEDIKKEMEILTSQLPWDALKTGISKLATSAES 589
Y +WI K G + Y +YKKA D + +P D LK +++T+ E+
Sbjct: 3822 YDEWISKVAGKVEGIRR-YAELYKKAKRVDTVNNFRRIEQMVPDDLLKRAFVRMSTTPEA 3880
Query: 588 FLALRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDFGYSFGTGVILLPVP 409
FL+LRS F+ S + L I ++ G+GDRHLSNF+++T+ G +I IDFG++FG+ LPVP
Sbjct: 3881 FLSLRSHFSSSHAVLCISHWILGIGDRHLSNFMINTETGGMIGIDFGHAFGSATQFLPVP 3940
Query: 408 ELIPFRLTPQFTNVLLPLDAVGLLRNDMISTLSALHSSRDVLSAVLDVFTNEPLMDWKNE 229
EL+PFRLT QF N++ PL GL+++ M+ +L A + D+L +DVF EP +DWKN
Sbjct: 3941 ELMPFRLTRQFINLMRPLAESGLIQSVMVHSLRAFRAEPDLLLNTMDVFVKEPSLDWKNF 4000
Query: 228 AMRTSSMRKTDKKNVDLESQDFEINTHEEQHVALKVENAHRKLNLWNPAEIVVSEL 61
++ T ++V+ + EIN Q KV A RKL NP+ I EL
Sbjct: 4001 ELKQLKKGGTWTESVNTK----EINWFPLQ----KVNFARRKLEGTNPSVITSEEL 4048
>ref|XP_002110143.1| hypothetical protein TRIADDRAFT_20924 [Trichoplax adhaerens]
gi|190588267|gb|EDV28309.1| hypothetical protein
TRIADDRAFT_20924, partial [Trichoplax adhaerens]
Length = 4042
Score = 390 bits (1001), Expect = e-105
Identities = 249/730 (34%), Positives = 386/730 (52%), Gaps = 20/730 (2%)
Frame = -2
Query: 2175 KAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKGDVSASLPPSSEYPVLVVRYIMKAIQMD 1996
+A + FCD++L + NQ KG + + +P +++RY ++A+
Sbjct: 3316 EAMMMMVNFCDDILRHEEDGQANQP------KGLIDTKI-----FPEVIIRYTLEAMAY- 3363
Query: 1995 NNLQIQHGIARVLTLLGHYSNTHSEFVHQQNGIPCWLFIAWIPQILAVLEKEEGAVLVSV 1816
N++ + R+L ++ NT F+ + + IP W+FI WI Q++A+L+K E + +
Sbjct: 3364 NSMDARQRFPRLLQIVERNPNTIDGFMRKSSAIPSWMFIGWISQMMAILDKPEARAVQEI 3423
Query: 1815 LEDIAHLYPQALYFPYNASKSDF-------GPIGQERTSKISALLNNPLLNGLVHALEDL 1657
L IA YPQA+ + + S + G + SK+S+ L PL+ V ALE L
Sbjct: 3424 LFRIADEYPQAIIYAFKVSNEQYTFEETSVGRQNKTAVSKLSSKLQLPLIESFVRALEQL 3483
Query: 1656 TYPEQRLQYWLSHIRNCISV-GNTKDAEATFHQMFEDCL------DSEAMSSRKSG---- 1510
+ P+ + W+ ++ G+ ++ +Q D L +SEA SS SG
Sbjct: 3484 SQPDLVFKDWVDEVKGLKKKSGSIAESIRICYQKLRDGLLVDASNESEAASSLTSGELIE 3543
Query: 1509 --TYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESIKDLAENLAKSQRNLQTGKISL 1336
++ +F + + K + + G +GSKLQSM + + L + ++ +N +L
Sbjct: 3544 FGSHKRRFIQHFGKVIEQYFGKDGSKLQSMKASDFEKIASRLIQEISGKIKNRPE---NL 3600
Query: 1335 GSLSKWMAEYDESGVFVRQVAXXXXXXXXSDEEFNKSFIEIPGHYTGFKKPDPCSHVKLI 1156
W++ + + F S IE+PG YTG KP P H+K+
Sbjct: 3601 KEYCPWLSNFQAAN-------------------FTYS-IEVPGQYTGRSKPLPEYHLKIA 3640
Query: 1155 SFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLRLDQRIEQLFGVMNEILSRDIV 976
SF + L L S ++P L + G DEK+Y FLVK GEDLRLDQRIEQLF VMNEIL++D +
Sbjct: 3641 SFGERLLVLKSIRKPLRLTIHGDDEKEYLFLVKCGEDLRLDQRIEQLFCVMNEILAQDSI 3700
Query: 975 CSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDGLMHKMPSVRHATSKQEKNTPA 796
CS++ L LRTY V+PI+++ G+IE++++T + + + D + +H S Q N+P
Sbjct: 3701 CSQQDLRLRTYQVIPITQRLGLIEWMKNTITLKEFVTDAMEDH--EKQHYLSSQ--NSPH 3756
Query: 795 GLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAEDIKKEMEILTSQLPWDALKTGI 616
L Y W L K GS+ Y +MY+KA +++ + + +PWD L+ G
Sbjct: 3757 KL-------YSKW-LGKFGSAGDPFYMYQSMYRKAKRSEVENHFKFRENSVPWDLLRRGF 3808
Query: 615 SKLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDFGYSFG 436
L+ S+E++L LRS F R+ + +SIC Y+ G+GDRHLSNF++D G +I IDFG++FG
Sbjct: 3809 VALSASSEAYLMLRSHFARTHATVSICHYLLGIGDRHLSNFMIDRLTGGMIGIDFGHAFG 3868
Query: 435 TGVILLPVPELIPFRLTPQFTNVLLPLDAVGLLRNDMISTLSALHSSRDVLSAVLDVFTN 256
+ LP+PEL+PFRLT Q N++LPL G L+ M+ TL AL + D+L +DVF
Sbjct: 3869 SATQFLPLPELMPFRLTRQMLNLMLPLRENGQLKCSMVHTLRALRNKPDLLVNTMDVFIK 3928
Query: 255 EPLMDWKNEAMRTSSMRKTDKKNVDLESQDFEINTHEEQHVALKVENAHRKLNLWNPAEI 76
EP +DW+N A R ++ K+ + ES DF E KV A RKL NPA +
Sbjct: 3929 EPSLDWQNFANRQNA-----KQGLKTESDDFSWYPRE------KVTFAKRKLKGANPAFV 3977
Query: 75 VVSELHSSVH 46
EL H
Sbjct: 3978 TRDELRLCHH 3987
>ref|XP_001626380.1| predicted protein [Nematostella vectensis]
gi|156213254|gb|EDO34280.1| predicted protein
[Nematostella vectensis]
Length = 1860
Score = 379 bits (973), Expect = e-102
Identities = 232/700 (33%), Positives = 366/700 (52%), Gaps = 19/700 (2%)
Frame = -2
Query: 2043 YPVLVVRYIMKAIQMDNNLQIQHGIARVLTLLGHYSNTHSEFVHQQNGIPCWLFIAWIPQ 1864
+P VVRY++KA++ + + ++ R+L ++ Y +T FV + +PCW+FI WI Q
Sbjct: 1182 FPEFVVRYVLKAMEHGSE-EARNRFPRLLQIVELYPHTLDSFVKKVETVPCWMFIGWINQ 1240
Query: 1863 ILAVLEKEEGAVLVSVLEDIAHLYPQALYFPYNASKSDF-------GPIGQERTSKISAL 1705
++A+++K+E + ++ +IA YPQAL + + S F G ++ +I L
Sbjct: 1241 MVALMDKKEARAVHGIVTEIAKNYPQALCYAFKVSSEQFVFDSSPEGNTNRKAVERIRKL 1300
Query: 1704 LNNPLLNGLVHALEDLTYPEQRLQYWLS-HIRNCISVGNTKDAEATFHQMFEDCLDSEAM 1528
L +PL++ + ALE L PE + W I+ + N K + F +++ DS
Sbjct: 1301 LESPLMDSFIAALEQLHNPEMAFKDWCDGEIKQLLQTKNKKAIKEAFRSIYKQLFDSSVN 1360
Query: 1527 SSRKS--------GTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESIKDLAENLAK 1372
+ S G + +KF+K+++ + G +G KL +M K + K + ++K
Sbjct: 1361 RATDSSQPAAEEMGPFRKKFSKEHASRFENIFGKDGEKLVNMSLK----TAKLKQQMVSK 1416
Query: 1371 SQRNLQTGKISLGSLSKWMAEYDESGVFVRQVAXXXXXXXXSDEEFNKSFIEIPGHYTGF 1192
NL+ S W+ + D K +E+PG YTG
Sbjct: 1417 PPGNLK-------EYSPWLTNFQA------------------DSHAQK--LEVPGQYTGQ 1449
Query: 1191 KKPDPCSHVKLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLRLDQRIEQLF 1012
KP P HV + FD+ + L+S ++PK + +RG DE+D+ FLVKGGED+RLDQRIEQLF
Sbjct: 1450 SKPMPEYHVNIAGFDEKVLVLASIRKPKRVTIRGDDERDHMFLVKGGEDIRLDQRIEQLF 1509
Query: 1011 GVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDGLMHKMPSVR 832
+MNE++S D CS++ L LRTY V+P++++ G+IE++++T + + L+H +
Sbjct: 1510 CMMNEVMSEDPACSQRNLRLRTYQVIPMTQRVGLIEWLKNTKPLKE-----LLHIAATES 1564
Query: 831 HATSKQEKNTPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAEDIKKEMEILT 652
+ + +L D I+ ++A+ D + E +
Sbjct: 1565 EKQAMVVRRKTKNMLDLTLRILFDIIIS----------------REANRTDTESEFKKKQ 1608
Query: 651 SQLPWDALKTGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRG 472
+Q+PWD L+ +LA S E++L LR+ F R+ + + IC YV G+GDRHLSNFL+D + G
Sbjct: 1609 AQVPWDLLRRAFQQLAASPEAYLTLRTHFARTHACICICQYVLGIGDRHLSNFLVDMRTG 1668
Query: 471 TLIPIDFGYSFGTGVILLPVPELIPFRLTPQFTNVLLPLDAVGLLRNDMISTLSALHSSR 292
LI IDFG+SFG+ LPVPEL+PFRLT QFTN+LLPL GL+RN MI + AL +
Sbjct: 1669 GLIGIDFGHSFGSATQFLPVPELVPFRLTRQFTNLLLPLKESGLVRNTMIHVMRALRGNH 1728
Query: 291 DVLSAVLDVFTNEPLMDWKNEAMRTSSMRKTDKKNVDLESQDFEINTHEEQ---HVALKV 121
++L +DVF EP +DW+ A + + E Q EI + E + KV
Sbjct: 1729 ELLLNTMDVFVKEPSLDWQMFARKQA------------EDQHMEIGMYYEDLTWYPREKV 1776
Query: 120 ENAHRKLNLWNPAEIVVSELHSSVHSGKTYLNNLERIVRG 1
A RKL NPA + EL H +++ NL+ G
Sbjct: 1777 LTAQRKLKGANPAFVTRQELELG-HRRRSWFRNLQSACLG 1815
>ref|XP_002680550.1| DNA dependent protein kinase catalytic subunit [Naegleria gruberi]
gi|284094171|gb|EFC47806.1| DNA dependent protein kinase
catalytic subunit [Naegleria gruberi]
Length = 4423
Score = 378 bits (971), Expect = e-102
Identities = 272/956 (28%), Positives = 457/956 (47%), Gaps = 77/956 (8%)
Frame = -2
Query: 2637 ILQGSYDASQGYMNQYMAAIEGSNKKEKLNFDF--FNTLVKLRCLQADRESTIDAFEAVT 2464
+ Q +Q + + ++ + L+FDF F +LVKL ++A + E
Sbjct: 3439 VAQSYLKVAQAASKKLLEVTNSADSSDALSFDFEFFKSLVKLLKIKALTSGRGSSSETKD 3498
Query: 2463 MLQQVRDYVTSTARK-------ALYQNQTKWRAGLKMLEGDVTSKLATFSLKSLSENSVS 2305
+ ++ ++ A K A T + K+L+ D S A +L+ ++ +
Sbjct: 3499 VFDKLIKFIKQNATKYGKEVNDASQTVPTSYVLTYKLLDADANSSFAN-TLRENTKLGGN 3557
Query: 2304 PKE-IENCVSLFGSAYAAYSKLFSEVSSADPFVHD--EFFTSRKIAKAYIKFAFFCDELL 2134
P++ ++ ++ + + +K ++ S+ + D + + AK Y+KFA FCDE+L
Sbjct: 3558 PEDYLQTALNRYKESVEIVNKNTNDDSNVVIKIEDGNNTISPYQSAKIYLKFAIFCDEIL 3617
Query: 2133 NCTKQTHWNQDLLLKLKKGDVSASLPPSSEYPVLVVRYIMKAIQMDNNLQIQHGIARVLT 1954
+ D L + + + S+ LP + +V ++ +++ N + + R+L
Sbjct: 3618 KERLGQKYTDDEDLVITR-EGSSKLPSNDILAEHIVENMLNSMKYYNK-EARDRFPRLLE 3675
Query: 1953 LLGHYSNTHSEFVH-----QQNGIPCWLFIAWIPQILAVLEKEEGAVLVSVLEDIAHLYP 1789
L+ + +T F IP W+FI WI Q+LA L EG L+ +L +A YP
Sbjct: 3676 LIEKFPSTRKIFAKFAPTSTSLQIPSWMFITWISQMLAHLTGPEGECLIPILLSLAENYP 3735
Query: 1788 QALYFPYNASKSDF------GPIGQERT-----SKISALLNNPLLNGLVHALEDLTYPEQ 1642
Q+LY+P N S D G G R + + NPL+ + +L+ L +PE
Sbjct: 3736 QSLYYPLNISSEDIIGSFERGNTGITRKVLEGIKLMKQKVRNPLIETFIFSLKKLNHPEL 3795
Query: 1641 RLQYWLSHIRNCISVGNTK-------DAEATFHQMFEDCLDSEAMSSRKSGTYNEKFAKD 1483
R + ++ I+ + N K D ++ + + F+D D A + G YN +FAK+
Sbjct: 3796 RFKAYMDDIKEIMKSKNYKSEKERKRDIKSKWEEAFDDLFDPNAPNV---GVYNTRFAKN 3852
Query: 1482 YSKKVLKALG-MNGSKLQSMDEKKYAESIKDLAENLAKSQRNLQTGKISLGSLSKWMAEY 1306
+ ++ K G +G+K+ M +K + + + + +++ + GK L SKWM ++
Sbjct: 3853 WVPQIKKDFGGRDGAKVMEMTDKTFEQLYAVKFKKMKETKGAMIPGKTKLEYFSKWMFDF 3912
Query: 1305 DESGVFVRQVAXXXXXXXXSDEEFNKSFIEIPGHY----------------------TGF 1192
+S R E +IE+PG Y
Sbjct: 3913 HQSST--RGSNETISSSSDVVENGGNFYIEVPGQYINNVGKAAAALMLGSVGMSSKQNNM 3970
Query: 1191 KKPDPCSHVKLISFDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLRLDQRIEQLF 1012
+ P HV++ISFD L +SS ++PK LK+ GSDEKDY FLVKGGEDLR DQRI+QLF
Sbjct: 3971 QAPSIDEHVRIISFDPNLLTMSSMRKPKRLKIHGSDEKDYAFLVKGGEDLRQDQRIQQLF 4030
Query: 1011 GVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDGLMHKMPSVR 832
VMN IL +D C ++ L++R Y VVP+S + G+IE++++T + +I + L
Sbjct: 4031 HVMNNILDKDTNCKQRDLNIRMYKVVPMSSEVGIIEWVDNTMPLKAIIEEQL-------N 4083
Query: 831 HATSKQEKNTPAGLLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAEDIKKEMEILT 652
T ++ +S+ + + + G+ L + Y Y A + +++ M+
Sbjct: 4084 KQTGTHDQEVLKHPSASIHLKMLEKVSGSKGAEYTLYQKYLVTYSNADQDMLEQTMDEQY 4143
Query: 651 SQLPWDALKTGISKLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRG 472
+ D L+ G+ LA S E++ +R++F +SL+ SI YV G+GDRHL NFL+D G
Sbjct: 4144 KLIDPDLLRNGLRSLAMSNEAYFTIRNRFAKSLATFSISSYVLGIGDRHLENFLVDFSEG 4203
Query: 471 TLIPIDFGYSFGTGVILLPVPELIPFRLTPQFTNVLLPLD-----------AVGLLRNDM 325
+LI IDFG++FG+ +LPVPEL+PFRLT Q + P+ GLL M
Sbjct: 4204 SLIGIDFGHAFGSATEILPVPELMPFRLTRQMLAIFSPISTTLDDFANENVGTGLLFESM 4263
Query: 324 ISTLSALHSSRDVLSAVLDVFTNEPLMDWKNEAMRTSSMRKTDKKNVD---LESQDFEIN 154
+ + ALH++R +L +DVF EPL+DW A + + +N+ S E +
Sbjct: 4264 VHCMRALHNNRHILLNTMDVFIKEPLVDWLKNAKKNPQFYQMSAENLPNSASSSSSSEAS 4323
Query: 153 THEEQ-----HVALKVENAHRKLNLWNPAEIVVSELHSSVHSGKTYLNNLERIVRG 1
+Q + KVE A KL L NP I S+ +++H K L ++R + G
Sbjct: 4324 QDGDQSLMKWYPQRKVELAKMKLELANPKVIFKSDAQANLHL-KKGLKYVDRAIEG 4378
>ref|XP_006021277.1| PREDICTED: DNA-dependent protein kinase catalytic subunit [Alligator
sinensis]
Length = 4112
Score = 376 bits (965), Expect = e-101
Identities = 248/781 (31%), Positives = 400/781 (51%), Gaps = 10/781 (1%)
Frame = -2
Query: 2373 LEGDVTSKLATFSLKSLSENSVSPKEIENCVSLFGSAYAAYSKLFSEVSSADPFVHDEFF 2194
LE D K++ S E SP+++ SL A+ +S + E
Sbjct: 3334 LEEDKVRKVSMLS----GEKPDSPEKV--IASLNKQAFQYFSNAVRKAEEEMQSRTMEHV 3387
Query: 2193 TSRKIAKAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKGDVSASLPPSSEYPVLVVRYIM 2014
+ AY+ FCD+ L+ K ++G S +P +VV ++
Sbjct: 3388 NLTGVIDAYLTLVDFCDKHLH-------------KEREGLSDISAVDLQTFPTIVVEKMI 3434
Query: 2013 KAIQMDNNLQIQHGIARVLTLLGHY-SNTHSEFVHQQNGIPCWLFIAWIPQILAVLEKEE 1837
KA+++ N+ + + R+L ++ Y + T S + + +PCW FI WI Q++AVL+K+E
Sbjct: 3435 KALKL-NSREARLKFPRLLQIIERYPAETLSLMAQEISTVPCWQFIGWISQMMAVLDKDE 3493
Query: 1836 GAVLVSVLEDIAHLYPQALYFPYNASKSDF-------GPIGQERTSKISALLNNP-LLNG 1681
+ +E+IAH YPQA+ FP+ S ++ G +E ++I + L+ ++
Sbjct: 3494 AVAVHHTVEEIAHNYPQAIIFPFMISSENYSFKDTATGHKNKEFVTRIKSKLDRGGVIQD 3553
Query: 1680 LVHALEDLTYPEQRLQYWLSHIRNCISVGNTKDAEATFHQMFEDCLDSEA-MSSRKSGTY 1504
V ALE L+ PE + W+ +RN +G + +A +M+E + + + G +
Sbjct: 3554 FVQALEQLSNPEMLFKDWVDAVRN--ELGKAQKNKAKLKEMYEGMYGNLGNLQASGLGLF 3611
Query: 1503 NEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESIKDLAENLAKSQRNLQTGKISLGSLS 1324
+F + Y K+ G GSKL M + ++ + + L + Q+ + G +L S
Sbjct: 3612 RRRFIQAYGKEFDTQFGKGGSKLLDMKDNEFIKIVNALLAKMRDGQK--EPG--NLKEYS 3667
Query: 1323 KWMAEYDESGVFVRQVAXXXXXXXXSDEEFNKSFIEIPGHYTGFKKPDPCSHVKLISFDQ 1144
W++E+ EF ++ +EIPG Y G KP P H K+ FD+
Sbjct: 3668 PWLSEFKA--------------------EFWRNELEIPGQYDGKGKPLPEYHAKISGFDE 3707
Query: 1143 TLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLRLDQRIEQLFGVMNEILSRDIVCSRK 964
+ + S ++PK + +RGSDE++Y FLVKGGEDLR DQRIEQLF VMN ILS+D CS++
Sbjct: 3708 RIKVMESLRKPKRIIIRGSDEREYPFLVKGGEDLRQDQRIEQLFDVMNIILSQDASCSQR 3767
Query: 963 KLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDGLMHKMPSVRHATSKQEKNTPAGLLS 784
+ ++TY V+P++ + G+IE++ +T + + + + + K + + G L
Sbjct: 3768 NMQIKTYQVIPMTTRLGLIEWLPNTCTLKNFLHSNMSEE--------EKADYCSEKGPLF 3819
Query: 783 SLRTQYQDWILKKGGSSAKLSESYTNMYKKASAEDIKKEMEILTSQLPWDALKTGISKLA 604
+ Y +W+ K G + Y MYK+AS + +++P D L+ K++
Sbjct: 3820 A----YNEWLSKMAGGKIEDFARYMPMYKRASRTETVMSFRNRENRVPEDLLRRAFVKMS 3875
Query: 603 TSAESFLALRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDFGYSFGTGVI 424
T+ E+FL+LRS FT S + + I ++ G+GDRHLSNF+++T+ G +I IDFGY+FG+
Sbjct: 3876 TAPEAFLSLRSHFTSSHALICISHWILGIGDRHLSNFMINTETGGIIGIDFGYAFGSATQ 3935
Query: 423 LLPVPELIPFRLTPQFTNVLLPLDAVGLLRNDMISTLSALHSSRDVLSAVLDVFTNEPLM 244
+LPVPEL+PFRLT QF N++LP+ GL+ + M L A D+L +DVF EP +
Sbjct: 3936 MLPVPELMPFRLTRQFINLMLPMKESGLIYSIMTHALRAYRKDPDLLINTMDVFVKEPSL 3995
Query: 243 DWKNEAMRTSSMRKTDKKNVDLESQDFEINTHEEQHVALKVENAHRKLNLWNPAEIVVSE 64
DWKN +R T K V+ E+N + Q KV RKL NPA I E
Sbjct: 3996 DWKNFELRLLKKGGTWLKEVN----TCEVNWYPLQ----KVNCVKRKLAGSNPAAITCEE 4047
Query: 63 L 61
L
Sbjct: 4048 L 4048
>ref|NP_989989.1| DNA-dependent protein kinase catalytic subunit [Gallus gallus]
gi|11761137|dbj|BAA36956.1| DNA-dependent protein kinase
catalytic subunit [Gallus gallus]
Length = 4133
Score = 376 bits (965), Expect = e-101
Identities = 250/804 (31%), Positives = 402/804 (50%), Gaps = 11/804 (1%)
Frame = -2
Query: 2379 KMLEGDVTSKLATFSLKSLSENSVSPKEIENCVSLFGSAYAAYSKLFSEVSSADPFVHDE 2200
+ +E + T K+ S E+S SP++I L A+ +S + + E
Sbjct: 3354 EQIEEEKTGKILELS----GESSESPEKI--LAGLNKRAFQCFSSAARKSEEEVQSLSME 3407
Query: 2199 FFTSRKIAKAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKGDVSASLPPSSEYPVLVVRY 2020
+ + AY+ FCD+ L K ++G + + +P +VV
Sbjct: 3408 HVDVKGVIDAYMTLVGFCDQHLR-------------KEEEGSLEINAADLQLFPAIVVEK 3454
Query: 2019 IMKAIQMDNNLQIQHGIARVLTLLGHY-SNTHSEFVHQQNGIPCWLFIAWIPQILAVLEK 1843
++KA+++ N+ + + R+L ++ Y + T + +PCW FI WI Q++A+L+K
Sbjct: 3455 MIKALKL-NSREARLRFPRLLQIIERYPAETLGLVTRELPSVPCWQFIGWISQMMALLDK 3513
Query: 1842 EEGAVLVSVLEDIAHLYPQALYFPYNASKSDF---GPIGQERTSKISALLNNPLLNG--- 1681
+E + +E+I YPQA+ +P+ S + R + A + N L G
Sbjct: 3514 DEAVAVQHTVEEIVDTYPQAIIYPFTISSESYCFKDTAAGCRNKEFVASIKNKLDRGGVV 3573
Query: 1680 --LVHALEDLTYPEQRLQYWLSHIRNCISVGNTKDAEATFHQMFEDCLDSEA-MSSRKSG 1510
+HALE L+ P + W++ +RN + T+ + +M+E + + + G
Sbjct: 3574 QDFIHALEQLSNPVMLFKDWVADVRN--ELVKTQRNKIILKEMYEGMYKNLGDVKAPGLG 3631
Query: 1509 TYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESIKDLAENLAKSQRNLQTGKISLGS 1330
++F + + K G GSKL M + E L + K+ + + G +L
Sbjct: 3632 WLRKRFVQAFGKDFDSHFGKGGSKLLDMKISDFNEITTALLTKMNKTHK--EPG--NLKE 3687
Query: 1329 LSKWMAEYDESGVFVRQVAXXXXXXXXSDEEFNKSFIEIPGHYTGFKKPDPCSHVKLISF 1150
S WM+E+ EF ++ +E+PG Y G KP P HVK+ F
Sbjct: 3688 CSPWMSEFRA--------------------EFLRNELEVPGQYDGKGKPLPEYHVKISGF 3727
Query: 1149 DQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLRLDQRIEQLFGVMNEILSRDIVCS 970
D+ + L S ++PK + +RGSDE+++ FLVKGGEDLR DQRIEQLF VMN +LSRD CS
Sbjct: 3728 DERIMVLESLRKPKRITIRGSDEQEHPFLVKGGEDLRQDQRIEQLFDVMNIVLSRDAACS 3787
Query: 969 RKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDGLMHKMPSVRHATSKQEKNTPAGL 790
++ + L+TY V+P++ + G+I+++E+T + + +R+ + +E++
Sbjct: 3788 QRNMQLKTYQVIPMTTRLGLIKWLENTCTLKEFLRNSMT------------EEEDANYNS 3835
Query: 789 LSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAEDIKKEMEILTSQLPWDALKTGISK 610
L R Y DW+ K GG + LS Y MYK AS + + S +P D L+ K
Sbjct: 3836 LKGPRAAYSDWLSKMGGKAQGLSR-YNAMYKNASRTETVIAFKSRESSVPEDLLRRAFVK 3894
Query: 609 LATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDFGYSFGTG 430
++TS E+FLALRS F S + + + ++ G+GDRHLSNF+++ + G ++ IDFG++FG+
Sbjct: 3895 MSTSPEAFLALRSHFVSSHALMCVSHWILGIGDRHLSNFMINKETGGMVGIDFGHAFGSA 3954
Query: 429 VILLPVPELIPFRLTPQFTNVLLPLDAVGLLRNDMISTLSALHSSRDVLSAVLDVFTNEP 250
LPVPEL+PFRLT QF N+++P+ GL+ + M+ L A + D+L + +DVF EP
Sbjct: 3955 TQFLPVPELMPFRLTRQFVNLMMPVKEWGLIYSVMVHALRAYRADPDLLISTMDVFVKEP 4014
Query: 249 LMDWKNEAMRTSSMRKTDKKNVDLESQDFEINTHEEQHVAL-KVENAHRKLNLWNPAEIV 73
+DWKN R T K EINT E L KV RKL NPA I
Sbjct: 4015 SLDWKNFEQRQLKKGGTWIK---------EINTAEVNWYPLQKVSYVKRKLTGANPARIT 4065
Query: 72 VSELHSSVHSGKTYLNNLERIVRG 1
EL + + N+ + RG
Sbjct: 4066 CDELRLG-YEKLPFYNDFAAVARG 4088
>sp|Q8QGX4.1|PRKDC_CHICK RecName: Full=DNA-dependent protein kinase catalytic subunit;
Short=DNA-PK catalytic subunit; Short=DNA-PKcs
gi|20334955|dbj|BAB91148.1| DNA-dependent protein kinase
catalytic subunit [Gallus gallus]
Length = 4134
Score = 376 bits (965), Expect = e-101
Identities = 250/804 (31%), Positives = 402/804 (50%), Gaps = 11/804 (1%)
Frame = -2
Query: 2379 KMLEGDVTSKLATFSLKSLSENSVSPKEIENCVSLFGSAYAAYSKLFSEVSSADPFVHDE 2200
+ +E + T K+ S E+S SP++I L A+ +S + + E
Sbjct: 3355 EQIEEEKTGKILELS----GESSESPEKI--LAGLNKRAFQCFSSAARKSEEEVQSLSME 3408
Query: 2199 FFTSRKIAKAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKGDVSASLPPSSEYPVLVVRY 2020
+ + AY+ FCD+ L K ++G + + +P +VV
Sbjct: 3409 HVDVKGVIDAYMTLVGFCDQHLR-------------KEEEGSLEINAADLQLFPAIVVEK 3455
Query: 2019 IMKAIQMDNNLQIQHGIARVLTLLGHY-SNTHSEFVHQQNGIPCWLFIAWIPQILAVLEK 1843
++KA+++ N+ + + R+L ++ Y + T + +PCW FI WI Q++A+L+K
Sbjct: 3456 MIKALKL-NSREARLRFPRLLQIIERYPAETLGLVTRELPSVPCWQFIGWISQMMALLDK 3514
Query: 1842 EEGAVLVSVLEDIAHLYPQALYFPYNASKSDF---GPIGQERTSKISALLNNPLLNG--- 1681
+E + +E+I YPQA+ +P+ S + R + A + N L G
Sbjct: 3515 DEAVAVQHTVEEIVDTYPQAIIYPFTISSESYCFKDTAAGCRNKEFVASIKNKLDRGGVV 3574
Query: 1680 --LVHALEDLTYPEQRLQYWLSHIRNCISVGNTKDAEATFHQMFEDCLDSEA-MSSRKSG 1510
+HALE L+ P + W++ +RN + T+ + +M+E + + + G
Sbjct: 3575 QDFIHALEQLSNPVMLFKDWVADVRN--ELVKTQRNKIILKEMYEGMYKNLGDVKAPGLG 3632
Query: 1509 TYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESIKDLAENLAKSQRNLQTGKISLGS 1330
++F + + K G GSKL M + E L + K+ + + G +L
Sbjct: 3633 WLRKRFVQAFGKDFDSHFGKGGSKLLDMKISDFNEITTALLTKMNKTHK--EPG--NLKE 3688
Query: 1329 LSKWMAEYDESGVFVRQVAXXXXXXXXSDEEFNKSFIEIPGHYTGFKKPDPCSHVKLISF 1150
S WM+E+ EF ++ +E+PG Y G KP P HVK+ F
Sbjct: 3689 CSPWMSEFRA--------------------EFLRNELEVPGQYDGKGKPLPEYHVKISGF 3728
Query: 1149 DQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLRLDQRIEQLFGVMNEILSRDIVCS 970
D+ + L S ++PK + +RGSDE+++ FLVKGGEDLR DQRIEQLF VMN +LSRD CS
Sbjct: 3729 DERIMVLESLRKPKRITIRGSDEQEHPFLVKGGEDLRQDQRIEQLFDVMNIVLSRDAACS 3788
Query: 969 RKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDGLMHKMPSVRHATSKQEKNTPAGL 790
++ + L+TY V+P++ + G+I+++E+T + + +R+ + +E++
Sbjct: 3789 QRNMQLKTYQVIPMTTRLGLIKWLENTCTLKEFLRNSMT------------EEEDANYNS 3836
Query: 789 LSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAEDIKKEMEILTSQLPWDALKTGISK 610
L R Y DW+ K GG + LS Y MYK AS + + S +P D L+ K
Sbjct: 3837 LKGPRAAYSDWLSKMGGKAQGLSR-YNAMYKNASRTETVIAFKSRESSVPEDLLRRAFVK 3895
Query: 609 LATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDFGYSFGTG 430
++TS E+FLALRS F S + + + ++ G+GDRHLSNF+++ + G ++ IDFG++FG+
Sbjct: 3896 MSTSPEAFLALRSHFVSSHALMCVSHWILGIGDRHLSNFMINKETGGMVGIDFGHAFGSA 3955
Query: 429 VILLPVPELIPFRLTPQFTNVLLPLDAVGLLRNDMISTLSALHSSRDVLSAVLDVFTNEP 250
LPVPEL+PFRLT QF N+++P+ GL+ + M+ L A + D+L + +DVF EP
Sbjct: 3956 TQFLPVPELMPFRLTRQFVNLMMPVKEWGLIYSVMVHALRAYRADPDLLISTMDVFVKEP 4015
Query: 249 LMDWKNEAMRTSSMRKTDKKNVDLESQDFEINTHEEQHVAL-KVENAHRKLNLWNPAEIV 73
+DWKN R T K EINT E L KV RKL NPA I
Sbjct: 4016 SLDWKNFEQRQLKKGGTWIK---------EINTAEVNWYPLQKVSYVKRKLTGANPARIT 4066
Query: 72 VSELHSSVHSGKTYLNNLERIVRG 1
EL + + N+ + RG
Sbjct: 4067 CDELRLG-YEKLPFYNDFAAVARG 4089
>ref|XP_004454094.1| PREDICTED: DNA-dependent protein kinase catalytic subunit [Dasypus
novemcinctus]
Length = 4124
Score = 374 bits (961), Expect = e-101
Identities = 262/822 (31%), Positives = 415/822 (50%), Gaps = 25/822 (3%)
Frame = -2
Query: 2448 RDYVTSTARKALYQNQTKWRAGLKMLEGDVTSKLATFSLKSLSENSVSPKEIENCVSLFG 2269
+D + T + + + A L +E T ++ T S S SEN+ E ++
Sbjct: 3322 QDILLGTTYRVIANALSSEPAYLGQIEESKTRRILTLSGSS-SENA------EKVIA--- 3371
Query: 2268 SAYAAYSKLFSEVSSADPFVHDEFFTSR-------KIAKAYIKFAFFCDELLNCTKQTHW 2110
Y K F +S A V +E + AY+ FCD W
Sbjct: 3372 ---GLYEKAFHYLSKAVRTVEEEIQNPTWDQVHLAGMIDAYMTLVDFCD----------W 3418
Query: 2109 NQDLLLKLKKGDVSASLPPSSE---YPVLVVRYIMKAIQMDNNLQIQHGIARVLTLLGHY 1939
+ L+KG+ + S+ S+E YP LVV ++KA+++++N + + R+L ++ Y
Sbjct: 3419 H------LRKGEENVSVIDSAELQTYPALVVDKMLKALKLNSN-EARLKFPRLLQIIEQY 3471
Query: 1938 -SNTHSEFVHQQNGIPCWLFIAWIPQILAVLEKEEGAVLVSVLEDIAHLYPQALYFPYNA 1762
T S + + IPCW FI WI Q++A+L+KEE + +E+IA YPQA+ +P+
Sbjct: 3472 PEETLSLMTKEMSSIPCWQFIGWISQLVALLDKEEAVAVQHTVEEIADSYPQAIVYPFII 3531
Query: 1761 SKSDF-------GPIGQERTSKISALLNNP-LLNGLVHALEDLTYPEQRLQYWLSHIRNC 1606
S + G +E ++I + L++ ++ ++ALE L+ PE + W + I+
Sbjct: 3532 SSESYSFKDTSLGHKNKEFVARIKSKLDHGGVIQDFINALEQLSNPEMLFKDWANDIKVE 3591
Query: 1605 ISVG--NTKDAEATFHQMFEDCLDSEAMSSRKSGTYNEKFAKDYSKKVLKALGMNGSKLQ 1432
+ N K+ E + +M+ D +A GT+ KF + + K+ K G GSKL
Sbjct: 3592 LEKTPVNKKNIEKMYERMYATLGDPKAQGL---GTFRRKFVQAFGKEFDKHFGKGGSKLP 3648
Query: 1431 SMDEKKYAESIKDLAENLAKSQRNLQTGKISLGSLSKWMAEYDESGVFVRQVAXXXXXXX 1252
M ++ ++A +L + +L S WM+++
Sbjct: 3649 GMKPCDFS----NIANSLCNKMSEVSKPPGNLKECSPWMSDFKV---------------- 3688
Query: 1251 XSDEEFNKSFIEIPGHYTGFKKPDPCSHVKLISFDQTLTCLSSKQRPKILKMRGSDEKDY 1072
EF ++ +EIPG Y G KP P H ++ FD+ + + S +RPK + +RG DE++Y
Sbjct: 3689 ----EFLRNELEIPGQYDGKGKPLPEYHARISGFDERIKVMPSVRRPKRIIIRGHDEREY 3744
Query: 1071 KFLVKGGEDLRLDQRIEQLFGVMNEILSRDIVCSRKKLSLRTYAVVPISKQCGVIEFIED 892
FLVKGGEDLR DQRIEQLF VMN ILS+D CS++ + L+TY V+P++ + G+IE+IE+
Sbjct: 3745 PFLVKGGEDLRQDQRIEQLFEVMNVILSQDPACSQRSMQLKTYQVIPMTTRLGLIEWIEN 3804
Query: 891 TSVIDDVIRDGLMHKMPSVRHATSKQEKNTPAGLLSSLRTQYQDWILKKGGSSAKLSESY 712
T + +++ + +++EK + + +Y+DW+ K G + Y
Sbjct: 3805 TLTLKELLLSSM-----------TQEEKTAYMSDPKAPQFEYRDWLTKMSGKRGVAA--Y 3851
Query: 711 TNMYKKASAEDIKKEMEILTSQLPWDALKTGISKLATSAESFLALRSQFTRSLSALSICC 532
MYK AS + S++P D LK K++ E+FLALRS F S + + I
Sbjct: 3852 MPMYKGASRTETVTSFRKRESKVPADLLKRAFVKMSVGPEAFLALRSHFASSHALMCISH 3911
Query: 531 YVAGVGDRHLSNFLLDTKRGTLIPIDFGYSFGTGVILLPVPELIPFRLTPQFTNVLLPLD 352
++ G+GDRHLSNFL++ + G+L IDFG++FG+ LPVPEL+PFRLT QF +++LP+
Sbjct: 3912 WILGIGDRHLSNFLVNVETGSLAGIDFGHAFGSATQFLPVPELMPFRLTRQFVSLMLPMR 3971
Query: 351 AVGLLRNDMISTLSALHSSRDVLSAVLDVFTNEPLMDWKN---EAMRTSSMRKTDKKNVD 181
GLL + M+ L A + D+L+ +DVF +P DWKN E +R
Sbjct: 3972 EAGLLDSVMVHALRAFRAHPDLLTNTMDVFVKDPSFDWKNFEREMLRRGG---------- 4021
Query: 180 LESQDFEIN-THEEQHVALKVENAHRKLNLWNPAEIVVSELH 58
S EIN T + + K+ A RKL NPA I ELH
Sbjct: 4022 --SWIQEINVTEKNWYPQQKINYAIRKLAGANPAVITCDELH 4061
>ref|XP_006268879.1| PREDICTED: DNA-dependent protein kinase catalytic subunit [Alligator
mississippiensis]
Length = 4132
Score = 373 bits (957), Expect = e-100
Identities = 248/784 (31%), Positives = 401/784 (51%), Gaps = 10/784 (1%)
Frame = -2
Query: 2382 LKMLEGDVTSKLATFSLKSLSENSVSPKEIENCVSLFGSAYAAYSKLFSEVSSADPFVHD 2203
L+ LE D K++ S E SP+++ SL A+ +S +
Sbjct: 3351 LEELEEDKVRKVSMLS----GEKPDSPEKV--IASLNKQAFQYFSNAVRKAEEEMQSRTM 3404
Query: 2202 EFFTSRKIAKAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKGDVSASLPPSSEYPVLVVR 2023
E + AY+ FCD K H ++ L + D+ +P +VV
Sbjct: 3405 EHVNLTGVIDAYLTLVDFCD------KHLHKEEEGLSDISAVDLQT-------FPAIVVE 3451
Query: 2022 YIMKAIQMDNNLQIQHGIARVLTLLGHY-SNTHSEFVHQQNGIPCWLFIAWIPQILAVLE 1846
++KA+++ N+ + + R+L ++ Y + T S + + +PCW FI WI Q++AVL+
Sbjct: 3452 KMIKALKL-NSREARLKFPRLLQIIERYPAETLSLMAQEISTVPCWQFIGWISQMMAVLD 3510
Query: 1845 KEEGAVLVSVLEDIAHLYPQALYFPYNASKSDF-------GPIGQERTSKISALLNNP-L 1690
K+E + +E+IA YPQA+ FP+ S ++ G +E ++I + L+ +
Sbjct: 3511 KDEAVAVHHTVEEIADNYPQAIIFPFMISSENYSFKDTAXGHKNKEFVTRIKSKLDRGGV 3570
Query: 1689 LNGLVHALEDLTYPEQRLQYWLSHIRNCISVGNTKDAEATFHQMFEDCLDSEA-MSSRKS 1513
+ V ALE L+ PE + W+ +RN +G + +A +M+E + + +
Sbjct: 3571 IQDFVQALEQLSNPEMLFKDWVDAVRN--ELGKAQKNKAKLKEMYEGMYGNLGNLQASGL 3628
Query: 1512 GTYNEKFAKDYSKKVLKALGMNGSKLQSMDEKKYAESIKDLAENLAKSQRNLQTGKISLG 1333
G + +F + Y K+ G GSKL M + ++ + + L + Q+ + G +L
Sbjct: 3629 GLFRRRFIQAYGKEFDTQFGKGGSKLLDMKDNEFIKIVNALLAKMRDGQK--EPG--NLK 3684
Query: 1332 SLSKWMAEYDESGVFVRQVAXXXXXXXXSDEEFNKSFIEIPGHYTGFKKPDPCSHVKLIS 1153
S W++E+ EF ++ +EIPG Y G KP P H K+
Sbjct: 3685 EYSPWLSEFKA--------------------EFWRNELEIPGQYDGKGKPLPEYHAKISG 3724
Query: 1152 FDQTLTCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLRLDQRIEQLFGVMNEILSRDIVC 973
FD+ + + S ++PK + +RGSDE++Y FLVKGGEDLR DQRIEQLF VMN ILS+D C
Sbjct: 3725 FDERIKVMESLRKPKRIIIRGSDEREYPFLVKGGEDLRQDQRIEQLFDVMNIILSQDASC 3784
Query: 972 SRKKLSLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDGLMHKMPSVRHATSKQEKNTPAG 793
S++ + ++TY V+P++ + G+IE++ +T + + + + + K + + G
Sbjct: 3785 SQRNMQIKTYQVIPMTTRLGLIEWLPNTCTLKNFLHSNMSEE--------EKADYCSEKG 3836
Query: 792 LLSSLRTQYQDWILKKGGSSAKLSESYTNMYKKASAEDIKKEMEILTSQLPWDALKTGIS 613
L + Y +W+ K G + Y MYK+AS + +++P D L+
Sbjct: 3837 PLFA----YNEWLSKMAGGKIEDFARYMPMYKRASRTETVMSFRNRENRVPKDLLRRAFV 3892
Query: 612 KLATSAESFLALRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDFGYSFGT 433
K++T+ E+FL+LRS FT S + + I ++ G+GDRHLSNF+++T+ G +I IDFGY+FG+
Sbjct: 3893 KMSTAPEAFLSLRSHFTSSHALICISHWILGIGDRHLSNFMINTETGGIIGIDFGYAFGS 3952
Query: 432 GVILLPVPELIPFRLTPQFTNVLLPLDAVGLLRNDMISTLSALHSSRDVLSAVLDVFTNE 253
+LPVPEL+PFRLT QF N++LP+ GL+ + M L A D+L +DVF E
Sbjct: 3953 ATQMLPVPELMPFRLTHQFINLMLPMKESGLIYSIMRHALRAYRKDPDLLINTMDVFVKE 4012
Query: 252 PLMDWKNEAMRTSSMRKTDKKNVDLESQDFEINTHEEQHVALKVENAHRKLNLWNPAEIV 73
P +DWKN +R T K V+ E+N + Q KV RKL NPA I
Sbjct: 4013 PSLDWKNFELRLLKKGGTWLKEVN----TCEVNWYPLQ----KVNCVKRKLAGSNPAAIT 4064
Query: 72 VSEL 61
EL
Sbjct: 4065 CEEL 4068
>dbj|BAA19566.1| DNA-PKcs [Mus musculus] gi|3241860|dbj|BAA28875.1| DNA-PKcs [Mus
musculus] gi|20336479|dbj|BAB91149.1| DNA-dependent
protein kinase catalytic subunit [Mus musculus]
Length = 4128
Score = 370 bits (950), Expect = 2e-99
Identities = 259/860 (30%), Positives = 425/860 (49%), Gaps = 24/860 (2%)
Frame = -2
Query: 2508 QADRESTIDAFEAVTMLQQ--VRDYVTSTARKALYQNQTKWRAGLKMLEGDVTSKLATFS 2335
Q+ RE ++ + +T+L + + +Y+ + + Q+ M +
Sbjct: 3291 QSPREQVLNTLKTITLLDESDISNYLNKNIQASCDQSILLGTTCRIMADALSREPACLSD 3350
Query: 2334 LKSLSENSVSPKEIENCVSLFGSAYAAYSKLFSEVSSADPFVHDEFFTS-------RKIA 2176
L+ NS+ N + Y + F +S A +E S + A
Sbjct: 3351 LEENKVNSILTLSGSNAENTETVITGLYQRAFHHLSKAVQSAEEETQLSCWGHEAAAERA 3410
Query: 2175 KAYIKFAFFCDELLNCTKQTHWNQDLLLKLKKGDVSASLPPSSE---YPVLVVRYIMKAI 2005
AY+ FCD+ +L+K + SAS S+E YP LVV +++A+
Sbjct: 3411 HAYMTLVGFCDQ----------------QLRKVEESASQKTSAEMEAYPALVVEKMLRAL 3454
Query: 2004 QMDNNLQIQHGIARVLTLLGHYSN-THSEFVHQQNGIPCWLFIAWIPQILAVLEKEEGAV 1828
++ N+ + + R+L ++ YS T + + + IPCW FI WI ++A+L+KEE
Sbjct: 3455 KL-NSSEARLKFPRLLQIIEQYSEETLNIMTKEISSIPCWQFIGWISHMMALLDKEEAIA 3513
Query: 1827 LVSVLEDIAHLYPQALYFPYNASKSDF-------GPIGQERTSKISALLNN-PLLNGLVH 1672
+ +E+IA YPQA+ +P+ S + G + +I + L++ +++ ++
Sbjct: 3514 VQHTVEEIADNYPQAIIYPFIISSESYSFKNTSSGHNNKAFVERIKSKLDHGEVIHSFIN 3573
Query: 1671 ALEDLTYPEQRLQYWLSHIRNCISVG--NTKDAEATFHQMFEDCLDSEAMSSRKSGTYNE 1498
AL+ L+ P+ + W+S ++ + N K+ E + +M+ D A G +
Sbjct: 3574 ALDQLSNPDLLFKDWVSDTKDELGKNPVNKKNIEKLYERMYAALGDLRAPGL---GPFRR 3630
Query: 1497 KFAKDYSKKVLKALGMNGSKLQSMDEKKYAESIKDLAENLAKSQRNLQTGKISLGSLSKW 1318
+F + + K+ +K+ G GSKL +M + + L + K + +L S W
Sbjct: 3631 RFIQAFGKEFVKSFGNGGSKLLTMKVDDFCKITGSLLVRMKKDSKLPG----NLKEYSPW 3686
Query: 1317 MAEYDESGVFVRQVAXXXXXXXXSDEEFNKSFIEIPGHYTGFKKPDPCSHVKLISFDQTL 1138
M+E+ +F K+ +EIPG Y G KP P HV++ FD+ +
Sbjct: 3687 MSEFKA--------------------QFLKNELEIPGQYDGKSKPLPEYHVRISGFDERV 3726
Query: 1137 TCLSSKQRPKILKMRGSDEKDYKFLVKGGEDLRLDQRIEQLFGVMNEILSRDIVCSRKKL 958
+ S ++PK + +RG DEK+Y FLVKGGEDLR DQRIEQ+F VMN ILS+D CS++ +
Sbjct: 3727 KVMLSLRKPKRIVIRGHDEKEYPFLVKGGEDLRQDQRIEQIFEVMNAILSQDAACSQRNM 3786
Query: 957 SLRTYAVVPISKQCGVIEFIEDTSVIDDVIRDGLMHKMPSVRHATSKQEKNTPAGLLSSL 778
LRTY VVP++ + G+IE+IE+T + D+ L+ M + + P
Sbjct: 3787 QLRTYRVVPMTSRLGLIEWIENTMTLKDL----LLSNMSQEEKVANNSDPKAPI------ 3836
Query: 777 RTQYQDWILKKGGSSAKLSESYTNMYKKASAEDIKKEMEILTSQLPWDALKTGISKLATS 598
Y+DW++K G S + +Y MY +A+ + SQ+P D LK K++TS
Sbjct: 3837 -RDYKDWLMKVSGKSD--AGAYVLMYSRANRTETVVAFRRRESQVPPDLLKRAFVKMSTS 3893
Query: 597 AESFLALRSQFTRSLSALSICCYVAGVGDRHLSNFLLDTKRGTLIPIDFGYSFGTGVILL 418
E+FLALRS F S + L I ++ G+GDRHL+NF++ + G++I IDFG++FG+ L
Sbjct: 3894 PEAFLALRSHFASSHALLCISHWLLGIGDRHLNNFMVAMETGSVIGIDFGHAFGSATQFL 3953
Query: 417 PVPELIPFRLTPQFTNVLLPLDAVGLLRNDMISTLSALHSSRDVLSAVLDVFTNEPLMDW 238
PVPEL+PFRLT QF +++LP+ GL+ M+ L A S +L+ +++F EP DW
Sbjct: 3954 PVPELMPFRLTRQFVSLMLPMKETGLMCTVMVHALRAFRSCAGLLTDTMEIFVKEPSFDW 4013
Query: 237 KNEAMRTSSMRKTDKKNVDLESQDFEIN-THEEQHVALKVENAHRKLNLWNPAEIVVSEL 61
K + + +RK S EIN T + + K+ A RKL NPA I EL
Sbjct: 4014 K--SFEQTMLRKGG-------SWIQEINVTEKNWYPQHKIRYAKRKLAGANPAVITCDEL 4064
Query: 60 HSSVHSGKTYLNNLERIVRG 1
+ H + + + RG
Sbjct: 4065 YLG-HEASSAFRSYTAVARG 4083