BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Ephedra27_contig00000194
         (3229 letters)

Database: ./nr 
           37,332,560 sequences; 13,225,080,153 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_001318162.1| viral A-type inclusion protein [Trichomonas ...   145   1e-31
ref|XP_003701630.1| PREDICTED: major antigen-like [Megachile rot...   140   3e-30
ref|XP_653447.1| Viral A-type inclusion protein repeat [Entamoeb...   139   1e-29
ref|XP_001582404.1| viral A-type inclusion protein [Trichomonas ...   138   2e-29
ref|XP_001581403.1| viral A-type inclusion protein [Trichomonas ...   134   3e-28
ref|XP_006560777.1| PREDICTED: sporulation-specific protein 15 i...   133   6e-28
ref|XP_006560776.1| PREDICTED: sporulation-specific protein 15 i...   133   6e-28
ref|XP_001739846.1| intracellular protein transport protein USO1...   130   4e-27
gb|EGI67148.1| Cytochrome P450 6B3 [Acromyrmex echinatior]            130   5e-27
ref|XP_001310118.1| viral A-type inclusion protein [Trichomonas ...   130   5e-27
ref|XP_975536.2| PREDICTED: similar to viral A-type inclusion pr...   129   8e-27
ref|XP_001027466.1| Viral A-type inclusion protein repeat contai...   127   4e-26
ref|XP_001323236.1| viral A-type inclusion protein [Trichomonas ...   126   7e-26
ref|XP_001330650.1| viral A-type inclusion protein [Trichomonas ...   125   9e-26
ref|XP_001312904.1| viral A-type inclusion protein [Trichomonas ...   125   9e-26
ref|XP_001319569.1| viral A-type inclusion protein [Trichomonas ...   125   1e-25
ref|XP_816749.1| hypothetical protein [Trypanosoma cruzi strain ...   124   3e-25
ref|XP_003405305.1| PREDICTED: early endosome antigen 1 [Loxodon...   124   3e-25
ref|XP_001323102.1| viral A-type inclusion protein [Trichomonas ...   124   3e-25
ref|XP_005159743.1| PREDICTED: titin isoform X6 [Danio rerio]         123   5e-25

>ref|XP_001318162.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
            gi|121900914|gb|EAY05939.1| viral A-type inclusion
            protein, putative [Trichomonas vaginalis G3]
          Length = 5296

 Score =  145 bits (365), Expect = 1e-31
 Identities = 151/728 (20%), Positives = 316/728 (43%), Gaps = 71/728 (9%)
 Frame = -3

Query: 3209 LEDYYALQKKAGELQTKVHIREEESCKHLTEALEN-----HIYGSLLESCVVDREA---- 3057
            L+  YA+ +   + + + H +E +  K L E         H+ G  L+    D E     
Sbjct: 2680 LKQKYAVLEDQLKTEKENHQQEAQQLKELAEEDATPMVCIHVVGEKLKKLQNDNEKLSEN 2739

Query: 3056 ------HIKQLMEQMNALVKEKRE--------------LENDAQRGEEISQSLKDEVFQL 2937
                  +I +L +++N L K+ ++              L+  A   E  ++SLK+E   L
Sbjct: 2740 NDNLQKNINELKDKINGLEKQYKQDAAELSNVHHQLGALQEKATNLENENKSLKEENEDL 2799

Query: 2936 KEVSRLYEEEKQHTIELQENFNALRQKNEDICL-KIEANNNLLEQKDNIIVELSHKLQEN 2760
               ++  E+EKQ  +    N    +   E   + + + N++LL+Q D++ +EL    + N
Sbjct: 2800 MNQNKQLEKEKQQLLAQNSNLEENKNNQEQSLMNRKKKNDDLLKQIDDLKLELEELKRNN 2859

Query: 2759 EEQRSALQNDMQSVEQMHAVSQTERE-----------------ELNRQLVLLRDD----- 2646
             +  + LQN  Q +E M      ++E                 ELN   ++L +      
Sbjct: 2860 SQNETKLQNANQQIEMMKDQINNDKEQIKSAQDKLNDLQNKNNELNSNQIVLENQKKMYE 2919

Query: 2645 --VNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKE- 2475
               N +K +     D+      Q+ DL  Q   VS   AL +   Q+L S+L+ L   + 
Sbjct: 2920 GLYNDMKSSNDKLNDENRKKTDQIIDLTKQNAEVS---ALKLEN-QRLNSELEKLKSNQP 2975

Query: 2474 ------------ESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDL 2331
                        E  K QL   + + KQ+E E   L G +         L+  NE + + 
Sbjct: 2976 VSSNDPELQKQIEELKKQLNNLSNEKKQIETEKNGLQGQIGR-------LESQNESLIES 3028

Query: 2330 CKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEML 2151
             K +  ++ ++Q Q + + +++ ++           ++ T +++ N+    KV  + + L
Sbjct: 3029 KKDMKEQNDKLQAQMDEMRRENNSLR----------QNQTQLERTNNGLENKVGNLTDQL 3078

Query: 2150 LPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEV 1971
              +K+ + +L+++    + S  N+ + ++   E++ + K+ +  +++ +  E+++L+++ 
Sbjct: 3079 NQVKNQLSALQDQ----LKSKENENEKLRNEREKLANEKNSVELQSKDKDAEIIKLKSDA 3134

Query: 1970 DAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQA 1791
            + +   +  L  +   LQ  + +   ++   K ++NN+ ++N N+E +    + ++    
Sbjct: 3135 EHLNDKINSLNDEKNKLQQANDKLNDQIEQMKQQINNLTNENKNMEQEKAKNQEKIQNIE 3194

Query: 1790 QKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDI 1611
             K  Q++EE++ +E E++   +E++ LK  +KE  D         ++L           +
Sbjct: 3195 PKLKQLEEEKSKLEDENSQNENEIQRLKDTIKELSDKLAKSEEDNKLLKQSSSGTTDKQV 3254

Query: 1610 ESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLG 1431
            E     +E L ++ D+L  L +EN +LK +           N   ++AE  +  +SK L 
Sbjct: 3255 ED---LQEMLNKLRDDLKNLNSENEQLKQQKDQLSEKLNNSNNDKTKAETQNEQLSKQLE 3311

Query: 1430 --NGRANQ--REFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANK 1263
              N   NQ   +++N  +D + V++ K    +     +KL+ + E  + K   A    NK
Sbjct: 3312 QLNNEKNQMFNKYKNAIQDKAKVEIAKETLAK---DNEKLASEKESLQQKLDSANDEKNK 3368

Query: 1262 LEEMQQTL 1239
            LE+ +  L
Sbjct: 3369 LEQDKHKL 3376



 Score =  117 bits (293), Expect = 3e-23
 Identities = 153/686 (22%), Positives = 294/686 (42%), Gaps = 46/686 (6%)
 Frame = -3

Query: 3053 IKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENF 2874
            ++Q  ++ +AL ++K E++N      EI Q +KD   + +++ +  ++ +Q   E Q+  
Sbjct: 3457 LQQTEQEKSALEQQKNEIQNKLN---EIEQQMKDSEKEKEDIKQKLQQVEQEKSETQKKL 3513

Query: 2873 NALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQ 2694
                Q+  +I  K+E      +  +N   E   +LQE EE +  L N+    E+     Q
Sbjct: 3514 EEAEQQKNEIQNKLEQTEQEKKNLENEKAETEKRLQETEEAKKNLANEKSEAERKLEEVQ 3573

Query: 2693 TEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQ 2514
             E+ E  R+L       N  +EA     +++   +K+L++ E QK    K L  +   ++
Sbjct: 3574 NEKAETERKL-------NEAEEANKNLENEKNETQKKLEEAEQQKAETQKLLEQTEEAKK 3626

Query: 2513 KLASDL----KALSEKEESTKNQLLIQTEQNKQL-ELEIEKLYGSLQMKQMENTLLKDGN 2349
             LA++     + L E EE+ KN    ++E  ++L E++ EK     ++ + E       N
Sbjct: 3627 NLANEKSEAERKLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEANKNLEN 3686

Query: 2348 EKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTK-EVGRSATDMKKVNSDAGAKV 2172
            EK     KL   + ++ + Q+  +L+Q    +  LA  K E  R   + ++   +   + 
Sbjct: 3687 EKNETQKKLEEAEQQKAETQK--LLEQTEEAKKNLANEKSEAERKLQETEEAKKNLANEK 3744

Query: 2171 SGILEMLLPMKDDVFSLK------EEVLGNINSLRNDAQM-----------VQVALEQMQ 2043
            S     L  ++++    +      EE   N+ + +N+ Q             Q  LEQ +
Sbjct: 3745 SEAERKLEEVQNEKAETERKLNEAEEANKNLENEKNETQKKLEEAEQQKAETQKLLEQTE 3804

Query: 2042 DTKSEL---FAEAEIRAQEV----LRLQAEVDAIQHILIELKRKNQTLQD---ESQRNAK 1893
            + K  L    +E E + QE       L+ E   IQ  L E K++   L++   E+Q+  +
Sbjct: 3805 EAKKNLENEKSETEKKLQETEEAKKNLEQEKSDIQKKLDETKQQKVNLENEKAETQKLLE 3864

Query: 1892 ELWNAKARLNNVMSKN----INLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSS 1725
            E   AK  L N  ++        E   ++L  E     +K  ++Q E+   E + N    
Sbjct: 3865 ETEEAKKNLENEKAETEKRLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLNEAEE 3924

Query: 1724 EVENLKSELKES-KDLEGYFLRLFEI-LLGQHVEVASLDIESCRFAEEKLMRILDELICL 1551
              +NL++E  E+ K LE    +  E   L +  E A  ++E+ +   EK ++  +E    
Sbjct: 3925 ANKNLENEKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLENEKSETEKKLQETEE--AK 3982

Query: 1550 RN-ENAKLKNEALYEYHDYERKNVSGSRAEAMSVL-----ISKSLGNGRA-NQREFQNKE 1392
            +N E  K   +   +    ++ N+   +AE   +L       K+L N +A  Q++    E
Sbjct: 3983 KNLEQEKSDIQKKLDETKQQKVNLENEKAETQKLLEETEEAKKNLENEKAETQKKLDEAE 4042

Query: 1391 EDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXX 1212
            E    ++  K+     E +++++  +    E +  E Q+   KLEE ++    +      
Sbjct: 4043 EAKKNLEQEKSDA---EKKLEEVQNEKSALENEKNETQK---KLEEAEKAKDQIVEEKSA 4096

Query: 1211 XXXXXIRVRSLKKENTRLRSEMKGEL 1134
                 +  +    EN + + E K +L
Sbjct: 4097 VERQLVESQKDSSENQKQQDEEKSKL 4122



 Score =  114 bits (286), Expect = 2e-22
 Identities = 174/904 (19%), Positives = 368/904 (40%), Gaps = 53/904 (5%)
 Frame = -3

Query: 3062 EAHIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIE-- 2889
            E  +KQL E+ + L  E  + EN+ QR ++  + L D++ + +E ++L ++    T +  
Sbjct: 3194 EPKLKQLEEEKSKLEDENSQNENEIQRLKDTIKELSDKLAKSEEDNKLLKQSSSGTTDKQ 3253

Query: 2888 ---LQENFNALR--------------QKNEDICLKIEANNNLLEQKDNIIVELSHKLQEN 2760
               LQE  N LR              Q+ + +  K+  +NN   + +    +LS +L++ 
Sbjct: 3254 VEDLQEMLNKLRDDLKNLNSENEQLKQQKDQLSEKLNNSNNDKTKAETQNEQLSKQLEQL 3313

Query: 2759 EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK-- 2586
              +++ + N  ++  Q  A  +  +E L +    L  +   L++ L  A D++  +E+  
Sbjct: 3314 NNEKNQMFNKYKNAIQDKAKVEIAKETLAKDNEKLASEKESLQQKLDSANDEKNKLEQDK 3373

Query: 2585 --------QLQD----LENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQT 2442
                    +L D    LEN+K  +++++    ++ QKL  +   L  +EE  +N+  ++ 
Sbjct: 3374 HKLEIDNTKLNDAKSHLENEKSQLAQQINDLNNKLQKLEEEKNKL--EEEKAQNEKKLEN 3431

Query: 2441 ---------EQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQ 2289
                     +QN+ L  ++E++   LQ  + E + L+    +I +       K  E++ Q
Sbjct: 3432 SQQDGDKLGQQNQDLLKQLEEIKQKLQQTEQEKSALEQQKNEIQN-------KLNEIEQQ 3484

Query: 2288 QEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEV 2109
             +   K+  +I+ +L +  E  +S T  K             LE     K+++ +  E+ 
Sbjct: 3485 MKDSEKEKEDIKQKLQQV-EQEKSETQKK-------------LEEAEQQKNEIQNKLEQT 3530

Query: 2108 LGNINSLRNDAQMVQVALEQMQDTKSELF---AEAEIRAQEVLRLQAEVDAIQHILIELK 1938
                 +L N+    +  L++ ++ K  L    +EAE + +EV   +AE +   +   E  
Sbjct: 3531 EQEKKNLENEKAETEKRLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEAN 3590

Query: 1937 RKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERN 1758
            +  +  ++E+Q+  +E    KA    ++ +    +    + K+E   + Q+  + ++   
Sbjct: 3591 KNLENEKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLANEKSEAERKLQETEEAKKNLA 3650

Query: 1757 VVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLM 1578
              +SE      EV+N K+E +   +                 E A+ ++E+ +   +K +
Sbjct: 3651 NEKSEAERKLEEVQNEKAETERKLN---------------EAEEANKNLENEKNETQKKL 3695

Query: 1577 RILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQN 1398
                       E  K + + L E  +  +KN++  ++EA   L         A +     
Sbjct: 3696 E--------EAEQQKAETQKLLEQTEEAKKNLANEKSEAERKLQETE----EAKKNLANE 3743

Query: 1397 KEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXX 1218
            K E    ++ ++N+    E   +KL+E  E  +    E  +   KLEE +Q  ++     
Sbjct: 3744 KSEAERKLEEVQNEKAETE---RKLNEAEEANKNLENEKNETQKKLEEAEQQKAETQKLL 3800

Query: 1217 XXXXXXXIRVRSLKKENTRL---RSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQ 1047
                     + + K E  +      E K  L   +S   ++    K+  +  E++    Q
Sbjct: 3801 EQTEEAKKNLENEKSETEKKLQETEEAKKNLEQEKSDIQKKLDETKQQKVNLENEKAETQ 3860

Query: 1046 XXXXXXXXXXXKIDTRTSETQE-IDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXX 870
                        ++   +ET++ +    +  +   N  S   ++ + +QN   E ++   
Sbjct: 3861 KLLEETEEAKKNLENEKAETEKRLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLN 3920

Query: 869  XXXXXXXXXXXKWGGIDMNSIEKQLKEL---NIHVMQLVEHNTRLKKDVKFGFAWANSMH 699
                            + N  +K+L+E         +L+E     KK+++         +
Sbjct: 3921 EAEEANKNLEN-----EKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLE---------N 3966

Query: 698  DLNGQEQKLKVDEEV-PILCHQNSKIAERLDINTDKARALDMEVQRIRLILSRIPTKPTE 522
            + +  E+KL+  EE    L  + S I ++LD    +   L+ E    + +L     + TE
Sbjct: 3967 EKSETEKKLQETEEAKKNLEQEKSDIQKKLDETKQQKVNLENEKAETQKLL-----EETE 4021

Query: 521  EASK 510
            EA K
Sbjct: 4022 EAKK 4025



 Score =  112 bits (281), Expect = 8e-22
 Identities = 165/867 (19%), Positives = 349/867 (40%), Gaps = 49/867 (5%)
 Frame = -3

Query: 3062 EAHIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQ 2883
            E   +QL +Q+  L  EK ++ N  +   +    ++     L + +     EK+   +  
Sbjct: 3300 ETQNEQLSKQLEQLNNEKNQMFNKYKNAIQDKAKVEIAKETLAKDNEKLASEKESLQQKL 3359

Query: 2882 ENFNALRQKNEDICLKIEANNNLLE-----------QKDNIIVELSHKLQENEEQRSALQ 2736
            ++ N  + K E    K+E +N  L            Q    I +L++KLQ+ EE+++ L+
Sbjct: 3360 DSANDEKNKLEQDKHKLEIDNTKLNDAKSHLENEKSQLAQQINDLNNKLQKLEEEKNKLE 3419

Query: 2735 NDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKE 2556
             +    E+    SQ + ++L +Q   L   +  +K+ L     +++ +E+Q  +++N+  
Sbjct: 3420 EEKAQNEKKLENSQQDGDKLGQQNQDLLKQLEEIKQKLQQTEQEKSALEQQKNEIQNKLN 3479

Query: 2555 TVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQM 2376
             + +++  S   ++ +   L+ + +++  T+ +L    +Q  +++ ++E+     +  + 
Sbjct: 3480 EIEQQMKDSEKEKEDIKQKLQQVEQEKSETQKKLEEAEQQKNEIQNKLEQTEQEKKNLEN 3539

Query: 2375 ENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKV 2196
            E    +   ++  +  K LA +  E + + E +  +    E +L   +E  ++  + K  
Sbjct: 3540 EKAETEKRLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEANKNLENEKNE 3599

Query: 2195 N-------SDAGAKVSGILEMLLPMKDDVFSLKEEVLGNI-------NSLRNDAQMVQVA 2058
                        A+   +LE     K ++ + K E    +        +L N+    +  
Sbjct: 3600 TQKKLEEAEQQKAETQKLLEQTEEAKKNLANEKSEAERKLQETEEAKKNLANEKSEAERK 3659

Query: 2057 LEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIEL---KRKNQTLQDESQRNAKEL 1887
            LE++Q+ K+E   +     +    L+ E +  Q  L E    K + Q L ++++   K L
Sbjct: 3660 LEEVQNEKAETERKLNEAEEANKNLENEKNETQKKLEEAEQQKAETQKLLEQTEEAKKNL 3719

Query: 1886 WNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLK 1707
             N K+     + +    E   ++L  E     +K  ++Q E+   E + N      +NL+
Sbjct: 3720 ANEKSEAERKLQET---EEAKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEANKNLE 3776

Query: 1706 SELKES-KDLEGYFLRLFEI-LLGQHVEVASLDIESCRFAEEKLMRILDELICLRN-ENA 1536
            +E  E+ K LE    +  E   L +  E A  ++E+ +   EK ++  +E    +N E  
Sbjct: 3777 NEKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLENEKSETEKKLQETEE--AKKNLEQE 3834

Query: 1535 KLKNEALYEYHDYERKNVSGSRAEAMSVL-----ISKSLGNGRA-NQREFQNKEEDSSGV 1374
            K   +   +    ++ N+   +AE   +L       K+L N +A  ++  Q  EE    +
Sbjct: 3835 KSDIQKKLDETKQQKVNLENEKAETQKLLEETEEAKKNLENEKAETEKRLQETEEAKKNL 3894

Query: 1373 DLLKNKCTRLEFQVQ--------KLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXX 1218
               K++  R   +VQ        KL+E  E  +    E  +   KLEE +Q  ++     
Sbjct: 3895 ANEKSEAERKLEEVQNEKAETERKLNEAEEANKNLENEKNETQKKLEEAEQQKAETQKLL 3954

Query: 1217 XXXXXXXIRVRSLKKENTRL---RSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQ 1047
                     + + K E  +      E K  L   +S   ++    K+  +  E++    Q
Sbjct: 3955 EQTEEAKKNLENEKSETEKKLQETEEAKKNLEQEKSDIQKKLDETKQQKVNLENEKAETQ 4014

Query: 1046 XXXXXXXXXXXKIDTRTSETQ-EIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXX 870
                        ++   +ETQ ++D   +  +      S   K+ + +QN    L+    
Sbjct: 4015 KLLEETEEAKKNLENEKAETQKKLDEAEEAKKNLEQEKSDAEKKLEEVQNEKSALEN--- 4071

Query: 869  XXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLN 690
                            + N  +K+L+E      Q+VE  + +++ +        S  D  
Sbjct: 4072 ----------------EKNETQKKLEEAEKAKDQIVEEKSAVERQL------VESQKD-- 4107

Query: 689  GQEQKLKVDEEVPILCHQNSKIAERLD 609
              E + + DEE   L  Q S +  +L+
Sbjct: 4108 SSENQKQQDEEKSKLQQQLSDLQNKLN 4134



 Score =  103 bits (256), Expect = 6e-19
 Identities = 190/1022 (18%), Positives = 400/1022 (39%), Gaps = 147/1022 (14%)
 Frame = -3

Query: 3218 QKILEDYYALQKKA-----GELQTKVHIREEESCKHLTEAL--ENHIYGSLLESCVVDRE 3060
            QK++ED  +  K+      G+    +  + +E  K L E L  +N    +L +      +
Sbjct: 2444 QKLIEDLQSNNKEPEKDDNGDFMNVLEKKSDEINKALEEILHRQNEEIKALRDREAEKNK 2503

Query: 3059 AHIKQLMEQ---MNALVKEKRELENDAQRGEEISQSLKDEVFQ------LKEVSRLYEE- 2910
              +  L +Q   +N  +K   + +ND  + E + Q ++ E  +      LK +   + E 
Sbjct: 2504 QTVDDLQKQIAMLNNKLKPSDQTDNDQLQKELMFQEIEGESPEDRNKRYLKAIEDKFNEI 2563

Query: 2909 --EKQHTIELQ-ENFNALRQKNEDI----CLKIEANNNLLEQKDNIIVELSHKLQENEEQ 2751
              + Q +I  Q E    LRQK + +        +    L E KDN   E + + +E EE 
Sbjct: 2564 IAKLQESINNQNEELKKLRQKCDGVDAIELQLAQKKAELNEIKDNYEKEKAEREKEVEEN 2623

Query: 2750 RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDL 2571
               L++ + ++E       ++ E+   ++          KE    AV  +  ++ +L +L
Sbjct: 2624 NKKLKDTINALENR---LDSQGEQTRSKINSAEQTARKAKEDADSAVIAQKSLQAELNNL 2680

Query: 2570 ENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKL---- 2403
            + +   +  +L       Q+ A  LK L+E++ +    + +  E+ K+L+ + EKL    
Sbjct: 2681 KQKYAVLEDQLKTEKENHQQEAQQLKELAEEDATPMVCIHVVGEKLKKLQNDNEKLSENN 2740

Query: 2402 ----------------------------------YGSLQMK----QMENTLLKDGNEKIY 2337
                                               G+LQ K    + EN  LK+ NE + 
Sbjct: 2741 DNLQKNINELKDKINGLEKQYKQDAAELSNVHHQLGALQEKATNLENENKSLKEENEDLM 2800

Query: 2336 DLCKLLATKSREV-----------QGQQEGILKQDINIEDELARTKEVGRSATDMKKVNS 2190
            +  K L  + +++             Q++ ++ +    +D L +  ++     ++K+ NS
Sbjct: 2801 NQNKQLEKEKQQLLAQNSNLEENKNNQEQSLMNRKKKNDDLLKQIDDLKLELEELKRNNS 2860

Query: 2189 DAGAKVSGILEMLLPMKDDVFSLKEEV------LGNINSLRNDAQMVQVALE-------- 2052
                K+    + +  MKD + + KE++      L ++ +  N+    Q+ LE        
Sbjct: 2861 QNETKLQNANQQIEMMKDQINNDKEQIKSAQDKLNDLQNKNNELNSNQIVLENQKKMYEG 2920

Query: 2051 ---QMQDTKSELFAEAEIRAQEVLRL---QAEVDAI----QHILIELK--RKNQTLQDES 1908
                M+ +  +L  E   +  +++ L    AEV A+    Q +  EL+  + NQ +    
Sbjct: 2921 LYNDMKSSNDKLNDENRKKTDQIIDLTKQNAEVSALKLENQRLNSELEKLKSNQPVSSND 2980

Query: 1907 QRNAKELWNAKARLNNVMSKNINLESQNRSLKAEL-HLQAQKAFQIQEERNVVESEHNVL 1731
                K++   K +LNN+ ++   +E++   L+ ++  L++Q    I+ ++++ E +++ L
Sbjct: 2981 PELQKQIEELKKQLNNLSNEKKQIETEKNGLQGQIGRLESQNESLIESKKDMKE-QNDKL 3039

Query: 1730 SSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICL 1551
             ++++ ++   +E+  L     +L     G   +V +L  +     + +L  + D+L   
Sbjct: 3040 QAQMDEMR---RENNSLRQNQTQLERTNNGLENKVGNL-TDQLNQVKNQLSALQDQLKSK 3095

Query: 1550 RNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLIS----------KSLGNGR-----AN 1416
             NEN KL+NE     ++     +     +A  + +            SL + +     AN
Sbjct: 3096 ENENEKLRNEREKLANEKNSVELQSKDKDAEIIKLKSDAEHLNDKINSLNDEKNKLQQAN 3155

Query: 1415 QREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEE------ 1254
             +     E+    ++ L N+   +E +  K  EK +  E K ++ ++  +KLE+      
Sbjct: 3156 DKLNDQIEQMKQQINNLTNENKNMEQEKAKNQEKIQNIEPKLKQLEEEKSKLEDENSQNE 3215

Query: 1253 -----MQQTLSDM------------XXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPS 1125
                 ++ T+ ++                        +V  L++   +LR ++K   + +
Sbjct: 3216 NEIQRLKDTIKELSDKLAKSEEDNKLLKQSSSGTTDKQVEDLQEMLNKLRDDLKNLNSEN 3275

Query: 1124 RSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYW 945
               K ++    +++N  + D T                 + +     +    + D  K  
Sbjct: 3276 EQLKQQKDQLSEKLNNSNNDKTKAETQNEQLSKQLEQLNNEKNQMFNKYKNAIQDKAKVE 3335

Query: 944  NRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQL 765
                   K  + L +  + LQQ                   + N +E+   +L I   +L
Sbjct: 3336 IAKETLAKDNEKLASEKESLQQKLDS------------ANDEKNKLEQDKHKLEIDNTKL 3383

Query: 764  VEHNTRLKKDVKFGFAWANSMHDLNGQEQKL-----KVDEEVPILCHQNSKIAERLDINT 600
             +  + L+ +       A  ++DLN + QKL     K++EE      QN K  E    + 
Sbjct: 3384 NDAKSHLENEKS---QLAQQINDLNNKLQKLEEEKNKLEEEKA----QNEKKLENSQQDG 3436

Query: 599  DK 594
            DK
Sbjct: 3437 DK 3438



 Score = 98.6 bits (244), Expect = 2e-17
 Identities = 115/547 (21%), Positives = 240/547 (43%), Gaps = 36/547 (6%)
 Frame = -3

Query: 3224 QHQKILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYG--SLLESCVVDREAHI 3051
            + +K +ED  A  + A + +T+  +++ E  K  TE    ++    S +E    + E  +
Sbjct: 4302 EEKKQVEDKLAATE-AAKKETEDKLKQTEDEKKATEDKLANVEAEKSDIEQAKKETEDKL 4360

Query: 3050 KQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFN 2871
            KQ  E+  A+  EK+  E+     EE  +  +D++ Q ++     E+ K+ T +  +   
Sbjct: 4361 KQTEEEKAAVEAEKKATEDKLHETEEAKKETEDKLKQTEDEKAAVEQAKKETEDKLKQTE 4420

Query: 2870 ALRQKNEDICLKIEANNNLLEQK---------------DNIIVELSHKLQENEEQRSALQ 2736
              ++  E+   + EA    L ++               +N++ +L  +L+  +E +S L+
Sbjct: 4421 EEKKATENKLEESEAEKKELGERFESSRGSTEKQVSDLENLLSKLKDELKNIKEDKSQLE 4480

Query: 2735 NDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKE 2556
            + ++  E     ++ +  +   +   L       ++ L+   +++   E Q  DL  +K 
Sbjct: 4481 SKLKQAEAEKKATEDKLAKTEVEKAALEQAKKETEDKLANVENEKKATETQKNDLAKEKT 4540

Query: 2555 TVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQM 2376
             + K LA  + R+++L ++ KAL EK  + +++   +  + K    E EK     ++KQ 
Sbjct: 4541 DLQKALAKLLKRQEQLDAEKKALEEKANALESEK--KATEEKLANAEKEKKETQDKLKQT 4598

Query: 2375 ENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQD--INIEDELARTKEVGRSATDMK 2202
            E+ L K  +EK     KL  T+S + Q +      +D   N E+E    +E  + + + K
Sbjct: 4599 EDNLAKSESEKKATEDKLKQTESEKAQIEAAKKETEDKLQNAENEKKAAEEKLKQSEEQK 4658

Query: 2201 KVN----SDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTK 2034
            K       +A A+     E L  ++ +   L       ++ L  +   ++  L+Q+ + K
Sbjct: 4659 KATEEKLQEAEAEKKAEQEKLANIEAEKQQLGNASEKQVSDLSGEISKLKQLLKQLAEAK 4718

Query: 2033 SELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQ---DESQRNAKELWNAKARLN 1863
             +   E     Q+  +   +   +Q  L  LK++ + L+    ES  N K L ++  +L 
Sbjct: 4719 KKADEELAKSKQDKEQSDNDKSKLQEDLNNLKKQLEDLEKAKKESDSNNKLLADSVNKLK 4778

Query: 1862 NVMSKNINLESQNRSLKAEL---------HLQAQKAF-QIQEERNVVESEHNVLSSEVEN 1713
               +K  + E +N + KA            ++ +KAF Q+ +    +E+E   L   V +
Sbjct: 4779 E-QNKQKDDEIKNLTDKANQPQDINNNPDFVKVKKAFLQLSKTNEKLENEKKALEGAVNS 4837

Query: 1712 LKSELKE 1692
            + S +K+
Sbjct: 4838 IYSTMKK 4844



 Score = 92.4 bits (228), Expect = 1e-15
 Identities = 166/838 (19%), Positives = 341/838 (40%), Gaps = 33/838 (3%)
 Frame = -3

Query: 3086 LESCVVDREAHIKQLMEQMNALVKEKRELENDAQRGEEIS------------QSLKDEVF 2943
            +E    ++E   K+L +  N L +   +LEN  ++  +              + LK+E  
Sbjct: 2065 IEQIKSEKEDQDKELEKLNNELTEALEKLENGKKKSSQEQNNENEEDFVDDIEKLKEERE 2124

Query: 2942 QLKEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQE 2763
             LK  +   + +      L+++   L++ N+D+       N   E K+N       K++E
Sbjct: 2125 NLKSENESLKNQAPENEGLKKSLENLKKSNDDL-------NKSNEDKEN-------KIKE 2170

Query: 2762 NEEQRSALQNDMQSVEQMHAVSQTEREELNRQL-----VLLRDDVNHLK--EALSMAVDD 2604
             E + S L++++  +EQ +     E E L+ ++     V L DD + +       ++VD+
Sbjct: 2171 LESEISKLKSEINELEQNNKDKDREIEILSSKVSSIENVNLDDDEDDITVVGTRDISVDE 2230

Query: 2603 RAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQL 2424
                + + +     +   +     + + E+ ++S      EK +S +++  ++ +Q KQL
Sbjct: 2231 TIPTDNETETKTEPETNTNTNENTNETNEENVSSQEGNNEEKNQSKEDKKKLRIQQLKQL 2290

Query: 2423 ELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDEL 2244
               +    G +   + +N  LK  NE +      L TK++E++ + E I   + N E E+
Sbjct: 2291 ---LASKQGEVDALKSQNDDLKSENETLSKSNHELGTKTKELEEEIENI---NNNKEGEV 2344

Query: 2243 ARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQ 2064
               KE    A+D++ V S         ++     ++D  +LK  +   ++ L N  +  +
Sbjct: 2345 IDEKE----ASDVEVVCSTRD------VDFEYENENDPETLKSLLKSKLSELENLQKENK 2394

Query: 2063 VALEQMQDTKSELFAEAEIRAQEVL----RLQAEVDAIQHILIELKRKNQTLQDESQRNA 1896
               +++     EL    + + +E+     RL  E++ +   L   +   Q L ++ Q N 
Sbjct: 2395 AKEDEITKLNEELAKSEDAKRRELAETAERLNNEINTLHDELQNEQNARQKLIEDLQSNN 2454

Query: 1895 KE-LWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNV--LSS 1725
            KE   +      NV+ K    +  N++L+  LH Q ++  +   +R   +++  V  L  
Sbjct: 2455 KEPEKDDNGDFMNVLEK--KSDEINKALEEILHRQNEE-IKALRDREAEKNKQTVDDLQK 2511

Query: 1724 EVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRF---AEEKLMRILDEL-I 1557
            ++  L ++LK S   +    +L + L+ Q +E  S +  + R+    E+K   I+ +L  
Sbjct: 2512 QIAMLNNKLKPSDQTDND--QLQKELMFQEIEGESPEDRNKRYLKAIEDKFNEIIAKLQE 2569

Query: 1556 CLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSG 1377
             + N+N +LK           R+   G  A  + +   K+  N   +  E +  E +   
Sbjct: 2570 SINNQNEELKK---------LRQKCDGVDAIELQLAQKKAELNEIKDNYEKEKAEREKEV 2620

Query: 1376 VDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXX 1197
             +  K     +     +L  + E   +K   A+Q A K +E      D            
Sbjct: 2621 EENNKKLKDTINALENRLDSQGEQTRSKINSAEQTARKAKE------DADSAVIAQKSLQ 2674

Query: 1196 IRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXX 1017
              + +LK++   L  ++K E    +    +E   +KE  + +ED TP++           
Sbjct: 2675 AELNNLKQKYAVLEDQLKTE----KENHQQEAQQLKE--LAEEDATPMVCIHVVG----- 2723

Query: 1016 XKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXX 837
                      +++  L +DN K      +  K    L++ +  L++              
Sbjct: 2724 ----------EKLKKLQNDNEKLSENNDNLQKNINELKDKINGLEKQYKQDAAELSNVHH 2773

Query: 836  KWGGID--MNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAW-ANSMHDLNGQEQKL 672
            + G +     ++E + K L      L+  N +L+K+ +   A  +N   + N QEQ L
Sbjct: 2774 QLGALQEKATNLENENKSLKEENEDLMNQNKQLEKEKQQLLAQNSNLEENKNNQEQSL 2831



 Score = 90.9 bits (224), Expect = 3e-15
 Identities = 137/685 (20%), Positives = 279/685 (40%), Gaps = 20/685 (2%)
 Frame = -3

Query: 3227 AQHQKILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIK 3048
            A+ QK+LE     +K     +++     E+  +   EA +N      LE    D +  + 
Sbjct: 3948 AETQKLLEQTEEAKKNLENEKSET----EKKLQETEEAKKN------LEQEKSDIQKKLD 3997

Query: 3047 QLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNA 2868
            +  +Q   L  EK E +   +  EE  ++L++E  + ++     EE K++          
Sbjct: 3998 ETKQQKVNLENEKAETQKLLEETEEAKKNLENEKAETQKKLDEAEEAKKN---------- 4047

Query: 2867 LRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQT- 2691
            L Q+  D   K+E   N     +N   E   KL+E E+ +  +  +  +VE+    SQ  
Sbjct: 4048 LEQEKSDAEKKLEEVQNEKSALENEKNETQKKLEEAEKAKDQIVEEKSAVERQLVESQKD 4107

Query: 2690 ----------EREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKE 2541
                      E+ +L +QL  L++ +N L++ L+   +++   + Q  DL+ Q + + K+
Sbjct: 4108 SSENQKQQDEEKSKLQQQLSDLQNKLNDLEKKLADKENEKEQEKTQKDDLQKQLDQLQKD 4167

Query: 2540 LALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLL 2361
                   +QKL     ++ E  +S KN LL      K            L      N  L
Sbjct: 4168 FDNLEREKQKLQDKNDSMKETIDS-KNMLLDSFGTIKD----------HLNDANNNNKKL 4216

Query: 2360 KDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAG 2181
            +D N K+ D  +   +K+ E+Q   + + ++  N++ E   T+E  ++  D  K  ++A 
Sbjct: 4217 QDENNKLRDDAQKATSKNNELQSIIDDLNRKLANLDAEKKATEEKLKNTEDKLK-QAEAE 4275

Query: 2180 AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQ----MVQVALEQMQDTKSELFAEA 2013
             K +   E  L   ++     EE L      +   +      + A ++ +D   +   E 
Sbjct: 4276 KKAT---EDKLRETENAKKETEEKLAKTEEEKKQVEDKLAATEAAKKETEDKLKQTEDEK 4332

Query: 2012 EIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLE 1833
            +    ++  ++AE   I+    E + K +  ++E      E    + +L+         E
Sbjct: 4333 KATEDKLANVEAEKSDIEQAKKETEDKLKQTEEEKAAVEAEKKATEDKLHETEEAKKETE 4392

Query: 1832 SQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFE 1653
             + +  + E     Q   + +++    E E     +++E  ++E KE             
Sbjct: 4393 DKLKQTEDEKAAVEQAKKETEDKLKQTEEEKKATENKLEESEAEKKE------------- 4439

Query: 1652 ILLGQHVEVASLDIE-SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERK---- 1488
              LG+  E +    E      E  L ++ DEL  ++ + ++L  E+  +  + E+K    
Sbjct: 4440 --LGERFESSRGSTEKQVSDLENLLSKLKDELKNIKEDKSQL--ESKLKQAEAEKKATED 4495

Query: 1487 NVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAE 1308
             ++ +  E  ++  +K     +    E + K  ++   DL K K T L+  + KL ++ E
Sbjct: 4496 KLAKTEVEKAALEQAKKETEDKLANVENEKKATETQKNDLAKEK-TDLQKALAKLLKRQE 4554

Query: 1307 MFETKSREAQQMANKLEEMQQTLSD 1233
              + + +  ++ AN LE  ++   +
Sbjct: 4555 QLDAEKKALEEKANALESEKKATEE 4579



 Score = 87.4 bits (215), Expect = 4e-14
 Identities = 168/806 (20%), Positives = 336/806 (41%), Gaps = 35/806 (4%)
 Frame = -3

Query: 3191 LQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNA---- 3024
            LQK   +L+   +++  +S K     LE+      L   +  + A ++QL  +  +    
Sbjct: 310  LQKLKEQLELYENMKNGQSMKERQAELES------LRLELEKKNAELEQLKARYQSKQDP 363

Query: 3023 -LVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNALRQKNED 2847
             L+ E   +EN+ Q    +   + D   Q+K ++ L  + +    + +E    L ++ +D
Sbjct: 364  QLLAEIERIENEVQN---LKNKIADRESQIKALNLLIAQYQTDDEDKKEIIENLEKEIKD 420

Query: 2846 ICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQ 2667
            +          +E KD  I  L  K+ + EE     +++   V     V   +  E   +
Sbjct: 421  L-------KKQIEDKDKEIEVLKAKIAKIEEIPEDEEDEDIVVAGTRDVDLGDFNEEEAE 473

Query: 2666 LVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKAL 2487
             V L D V  LKE L     +   M++ L   + + E +++++     R  K   +++ L
Sbjct: 474  QVSLEDQVKQLKEKLDDKKKNGVQMKQALASKDAEIEKLNEQIQELKDRNDKQEQNIEEL 533

Query: 2486 SEKEESTKN-----QLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKL 2322
            + K    +N     + LI   QN+  +L   K   S  +   ENT  K  +EK  D  + 
Sbjct: 534  NTKNSDLQNSNDEYKKLIDELQNQLKDLAKNKAESS-DLNNSENT--KQDSEKAED--EN 588

Query: 2321 LATKS-REVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLP 2145
              TKS +E+Q + + +  ++  ++  L   K   +S  D+ K N D   K+  +   +  
Sbjct: 589  AETKSNKELQEESDKLKSENEGLKKSLENLK---KSNDDLNKSNEDKENKIKELESEISK 645

Query: 2144 MKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDA 1965
            +K ++  L++      N+   D + +++   ++   ++    + E     V      VD 
Sbjct: 646  LKSEINELEQ------NNKDKDRE-IEILSSKVSSIENVNLDDDEDDITVVGTRDISVD- 697

Query: 1964 IQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQK 1785
             + I  + + + +T + E+  N  E  N +    NV S+  N E +N+S + +  L+ Q+
Sbjct: 698  -ETIPTDNETETKT-EPETNTNTNENTN-ETNEENVSSQEGNNEEKNQSKEDKKKLRIQQ 754

Query: 1784 AFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIES 1605
              Q+   +   + E + L S+ ++LKSE  E+     + L      L + +E  + + E 
Sbjct: 755  LKQLLASK---QGEVDALKSQNDDLKSE-NETLSKSNHELETKNKELEEEIENINNNKEG 810

Query: 1604 CRFAEEKLMRILDELIC--------LRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVL 1449
                E++   +  E++C          NEN     ++L +    E +N+     + M  +
Sbjct: 811  EVIDEKEASDV--EVVCSTRDVDFEYENENDPETLKSLLKSKLSELENLQKENTDLMKQI 868

Query: 1448 ISKSLGNGRAN-QREFQNKEEDSSGVDLLKNKCTRLEFQV-QKLSEKAEMFETKSREAQQ 1275
              + L N   N +RE +N + ++   + LK +  RL+    Q    K +M E  + +  Q
Sbjct: 869  --EELKNENENLKRELENLKLEN---ESLKRENERLQLTADQSPQSKDKMIELLANQINQ 923

Query: 1274 MANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSF 1095
            + + + E+QQ  +++              + +K+EN +L+ E + +L  S S K  E   
Sbjct: 924  LESLVPELQQKTNEIEELKKEN-------KQIKEENEKLKKENE-DLKKSGSNKSSE--- 972

Query: 1094 IKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRT-----SETQEIDTLMDD---------N 957
              EIN  +ED    I+             + +T      E +E+   ++D         +
Sbjct: 973  --EINQEEEDLKKQIEDLKKALGYPQDGKEHKTPSELIEENEELKKKVEDLEKESGYPSD 1030

Query: 956  RKYWNRVSHFTKQTQSLQNSVQELQQ 879
             K     S   K+ + L+  V +L++
Sbjct: 1031 NKEHKSPSELLKENEELKKKVDDLEK 1056



 Score = 85.1 bits (209), Expect = 2e-13
 Identities = 146/711 (20%), Positives = 295/711 (41%), Gaps = 49/711 (6%)
 Frame = -3

Query: 3224 QHQKILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQ 3045
            +++++ ++   L+K+  EL+ ++ I            ++  I G + ES   D     K 
Sbjct: 1861 ENEELKKENQRLKKENAELKKRLGI-----------PVDQIIEGIMNESTASDESEDNKS 1909

Query: 3044 LMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKE-VSRLYEEEKQHTIELQENFNA 2868
              E    +   K++LE+    G +  +++ +E  ++KE    L +  +Q   E  +  + 
Sbjct: 1910 PEELKREIENLKKQLEDLKNSGSQ--ENVDEENNEMKEGADNLIDALQQSVDEKNKQIDD 1967

Query: 2867 LRQKNED-------ICLKIEANNNLLEQKDN--IIVELSHKLQ-ENEEQRSALQNDMQSV 2718
            L+QK +D       +  K+E   N+ E++DN  I+V  +  ++ EN E+ S  +   +  
Sbjct: 1968 LQQKLDDQNREIELLKAKVEQIENINEEEDNEDIVVASTRDVELENVEEESPEEAKERLA 2027

Query: 2717 EQMHAVSQ--TERE----ELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKE 2556
            EQ+  +    TE++    ++ + L     +++ L E +     ++   +K+L+ L N+  
Sbjct: 2028 EQISQLQDKLTEKKKNSLQMKQALASKDAEISKLNEEIEQIKSEKEDQDKELEKLNNELT 2087

Query: 2555 TVSKELALSVSR---------EQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKL 2403
               ++L     +         E+    D++ L E+ E+ K+    + E  K    E E L
Sbjct: 2088 EALEKLENGKKKSSQEQNNENEEDFVDDIEKLKEERENLKS----ENESLKNQAPENEGL 2143

Query: 2402 YGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVG 2223
              SL+  +  N  L   NE   +  K L +   E+   +  I + + N +D+    + + 
Sbjct: 2144 KKSLENLKKSNDDLNKSNEDKENKIKELES---EISKLKSEINELEQNNKDKDREIEILS 2200

Query: 2222 RSATDMKKVNSD--------AGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMV 2067
               + ++ VN D         G +   + E +    +     + E   N N   N+    
Sbjct: 2201 SKVSSIENVNLDDDEDDITVVGTRDISVDETIPTDNETETKTEPETNTNTNENTNETNEE 2260

Query: 2066 QVALEQMQDTKSELFAE--AEIRAQEVLRL----QAEVDAIQHILIELKRKNQTLQDESQ 1905
             V+ ++  + +     E   ++R Q++ +L    Q EVDA++    +LK +N+TL   + 
Sbjct: 2261 NVSSQEGNNEEKNQSKEDKKKLRIQQLKQLLASKQGEVDALKSQNDDLKSENETLSKSNH 2320

Query: 1904 R---NAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNV 1734
                  KEL      +NN  +K   +  +  +   E+    +      E  N  E+  ++
Sbjct: 2321 ELGTKTKELEEEIENINN--NKEGEVIDEKEASDVEVVCSTRDVDFEYENENDPETLKSL 2378

Query: 1733 LSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELIC 1554
            L S++  L++  KE+K  E    +L E       E+A  +    R   E   R+ +E+  
Sbjct: 2379 LKSKLSELENLQKENKAKEDEITKLNE-------ELAKSEDAKRRELAETAERLNNEINT 2431

Query: 1553 LRNENAKLKNEALYEYHDYERKNVSGSR---AEAMSVLISKSLGNGRANQREFQNKEEDS 1383
            L +E    +N       D +  N    +    + M+VL  KS    +A +     + E+ 
Sbjct: 2432 LHDELQNEQNARQKLIEDLQSNNKEPEKDDNGDFMNVLEKKSDEINKALEEILHRQNEEI 2491

Query: 1382 SGV---DLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTL 1239
              +   +  KNK T     V  L ++  M   K + + Q  N  +++Q+ L
Sbjct: 2492 KALRDREAEKNKQT-----VDDLQKQIAMLNNKLKPSDQTDN--DQLQKEL 2535



 Score = 84.3 bits (207), Expect = 3e-13
 Identities = 164/841 (19%), Positives = 327/841 (38%), Gaps = 75/841 (8%)
 Frame = -3

Query: 3194 ALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLM-------- 3039
            A+ + A  L TKV+    E  +      E  I  S  +  V     HI+ +         
Sbjct: 216  AISQAALRLSTKVNSLNAELQELKHSQSEMQIIVSQYKEVVPKISFHIETIEKLVSINDT 275

Query: 3038 --EQMNALVKEKR--ELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEK--QHTIELQEN 2877
              +  N L+  +R   + ++ QR  + ++    E+ +LKE   LYE  K  Q   E Q  
Sbjct: 276  DEDDKNPLIFPQRLKRIRSEVQRLFDNNEKTNKELQKLKEQLELYENMKNGQSMKERQAE 335

Query: 2876 FNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQR-----SALQNDMQSVEQ 2712
              +LR       L++E  N  LEQ       L  + Q  ++ +       ++N++Q+++ 
Sbjct: 336  LESLR-------LELEKKNAELEQ-------LKARYQSKQDPQLLAEIERIENEVQNLKN 381

Query: 2711 MHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELAL 2532
              A  +++ + LN  +   + D    KE +         +EK+++DL+ Q E   KE+ +
Sbjct: 382  KIADRESQIKALNLLIAQYQTDDEDKKEIIEN-------LEKEIKDLKKQIEDKDKEIEV 434

Query: 2531 SVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQL----ELEIEKLYGSLQMKQMENTL 2364
              ++  K    ++ + E EE     +++   ++  L    E E E++    Q+KQ++   
Sbjct: 435  LKAKIAK----IEEIPEDEED--EDIVVAGTRDVDLGDFNEEEAEQVSLEDQVKQLKEK- 487

Query: 2363 LKDGNEKIYDLCKLLATKSREVQGQQEGIL-------KQDINIEDELARTKEVGRSATDM 2205
            L D  +    + + LA+K  E++   E I        KQ+ NIE+   +  ++  S  + 
Sbjct: 488  LDDKKKNGVQMKQALASKDAEIEKLNEQIQELKDRNDKQEQNIEELNTKNSDLQNSNDEY 547

Query: 2204 KKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKS-- 2031
            KK+          I E+   +KD   +  E    ++N+  N  Q  + A ++  +TKS  
Sbjct: 548  KKL----------IDELQNQLKDLAKNKAES--SDLNNSENTKQDSEKAEDENAETKSNK 595

Query: 2030 ELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMS 1851
            EL  E++       +L++E + ++  L  LK+ N  L   ++    ++   ++ ++ + S
Sbjct: 596  ELQEESD-------KLKSENEGLKKSLENLKKSNDDLNKSNEDKENKIKELESEISKLKS 648

Query: 1850 KNINLESQNRSLKAELHLQAQKAFQIQ--------------------------------- 1770
            +   LE  N+    E+ + + K   I+                                 
Sbjct: 649  EINELEQNNKDKDREIEILSSKVSSIENVNLDDDEDDITVVGTRDISVDETIPTDNETET 708

Query: 1769 ----------EERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVAS 1620
                       E     +E NV S E  N +    +    +    +L ++L  +  EV +
Sbjct: 709  KTEPETNTNTNENTNETNEENVSSQEGNNEEKNQSKEDKKKLRIQQLKQLLASKQGEVDA 768

Query: 1619 LDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISK 1440
            L  ++     E      +E +   N   + KN+ L E  +    N  G   +       +
Sbjct: 769  LKSQNDDLKSE------NETLSKSNHELETKNKELEEEIENINNNKEGEVIDEKEASDVE 822

Query: 1439 SLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKL 1260
             + + R    E++N+ +  +   LLK+K + LE   ++ ++  +  E    E + +  +L
Sbjct: 823  VVCSTRDVDFEYENENDPETLKSLLKSKLSELENLQKENTDLMKQIEELKNENENLKREL 882

Query: 1259 EEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEIN 1080
            E ++                 +   SLK+EN RL      +LT  +S + ++        
Sbjct: 883  ENLK-----------------LENESLKRENERL------QLTADQSPQSKD-------- 911

Query: 1079 IGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQN 900
                    +I+            +     +T EI+ L  +N++         K+ + L+ 
Sbjct: 912  -------KMIELLANQINQLESLVPELQQKTNEIEELKKENKQIKEENEKLKKENEDLKK 964

Query: 899  S 897
            S
Sbjct: 965  S 965



 Score = 69.7 bits (169), Expect = 8e-09
 Identities = 101/469 (21%), Positives = 197/469 (42%), Gaps = 48/469 (10%)
 Frame = -3

Query: 3194 ALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNALVK 3015
            AL++KA  L+++    EE+      E  E        E  +   E+  K   +++     
Sbjct: 4562 ALEEKANALESEKKATEEKLANAEKEKKETQDKLKQTEDNLAKSESEKKATEDKLKQTES 4621

Query: 3014 EKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNALRQKNEDICLK 2835
            EK ++E   +  E+  Q+ ++E    +E  +  EE+K+ T E  +   A ++  ++    
Sbjct: 4622 EKAQIEAAKKETEDKLQNAENEKKAAEEKLKQSEEQKKATEEKLQEAEAEKKAEQEKLAN 4681

Query: 2834 IEAN--------------------------NNLLEQKDNIIVELSHKLQENEE---QRSA 2742
            IEA                             L E K     EL+   Q+ E+    +S 
Sbjct: 4682 IEAEKQQLGNASEKQVSDLSGEISKLKQLLKQLAEAKKKADEELAKSKQDKEQSDNDKSK 4741

Query: 2741 LQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDD-RAFMEK--QLQDL 2571
            LQ D+ ++++     +  ++E +    LL D VN LKE      D+ +   +K  Q QD+
Sbjct: 4742 LQEDLNNLKKQLEDLEKAKKESDSNNKLLADSVNKLKEQNKQKDDEIKNLTDKANQPQDI 4801

Query: 2570 ENQKETVS-KELALSVSR-EQKLASDLKALS----------EKEEST----KNQLLIQTE 2439
             N  + V  K+  L +S+  +KL ++ KAL           +K++S     K   + Q E
Sbjct: 4802 NNNPDFVKVKKAFLQLSKTNEKLENEKKALEGAVNSIYSTMKKDDSAPLDEKATPMQQAE 4861

Query: 2438 QNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDIN 2259
            + K+L   I+   G     +    L  + N+    +CK+  T S          +  DI 
Sbjct: 4862 RAKEL---IQNNSGKKVDPEFFEKLTNEMNDLFNSICKVFRTNSP---------ITFDIK 4909

Query: 2258 IEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRND 2079
             E+++A    +G+++  ++KV          +   L  + +D+   K++    I+ L++D
Sbjct: 4910 KEEDIA---TIGQNSIVLRKV----------MKSYLTQLSNDIIKDKQQ----ISDLKHD 4952

Query: 2078 AQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRK 1932
               +Q+  E+++ T S   +  +I   ++++   +V A    L E +R+
Sbjct: 4953 KNSLQMENEEIKATASANMSSKDINNDKLIKSYKKVYARMKQLQEAERE 5001



 Score = 60.1 bits (144), Expect = 6e-06
 Identities = 119/532 (22%), Positives = 218/532 (40%), Gaps = 58/532 (10%)
 Frame = -3

Query: 3224 QHQKILEDYYALQKKAGELQTKVHIREEESCKHLTEALEN-HIYGSLLESCVVDREAHIK 3048
            Q  +  ED  A  K   ELQ +    + E+ + L ++LEN       L     D+E  IK
Sbjct: 579  QDSEKAEDENAETKSNKELQEESDKLKSEN-EGLKKSLENLKKSNDDLNKSNEDKENKIK 637

Query: 3047 QLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTI----ELQE 2880
            +L  +++ L  E  ELE + +  +   + L  +V  ++ V+ L ++E   T+    ++  
Sbjct: 638  ELESEISKLKSEINELEQNNKDKDREIEILSSKVSSIENVN-LDDDEDDITVVGTRDISV 696

Query: 2879 NFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQND-----MQSVE 2715
            +         +   + E N N  E  +    E     + N E+++  + D     +Q ++
Sbjct: 697  DETIPTDNETETKTEPETNTNTNENTNETNEENVSSQEGNNEEKNQSKEDKKKLRIQQLK 756

Query: 2714 QMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL-QDLEN--------- 2565
            Q+ A  Q E + L  Q     DD+    E LS +  +     K+L +++EN         
Sbjct: 757  QLLASKQGEVDALKSQ----NDDLKSENETLSKSNHELETKNKELEEEIENINNNKEGEV 812

Query: 2564 --QKETVSKELALSV----------SREQKLASDLKALSEKEESTKNQLLIQTEQNKQLE 2421
              +KE    E+  S           +  + L S LK+   + E+ + +     +Q ++L+
Sbjct: 813  IDEKEASDVEVVCSTRDVDFEYENENDPETLKSLLKSKLSELENLQKENTDLMKQIEELK 872

Query: 2420 LEIEKLYGSLQMKQMENTLLKDGNEKIY-----------DLCKLLATKSREVQGQQEGIL 2274
             E E L   L+  ++EN  LK  NE++             + +LLA +  +++     + 
Sbjct: 873  NENENLKRELENLKLENESLKRENERLQLTADQSPQSKDKMIELLANQINQLESLVPELQ 932

Query: 2273 KQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNIN 2094
            ++   IE+     K++      +KK N D   K SG  +             EE+     
Sbjct: 933  QKTNEIEELKKENKQIKEENEKLKKENED--LKKSGSNKS-----------SEEINQEEE 979

Query: 2093 SLRNDAQMVQVALEQMQD-----TKSELFAEAEIRAQEVLRLQAE----VDAIQH-ILIE 1944
             L+   + ++ AL   QD     T SEL  E E   ++V  L+ E     D  +H    E
Sbjct: 980  DLKKQIEDLKKALGYPQDGKEHKTPSELIEENEELKKKVEDLEKESGYPSDNKEHKSPSE 1039

Query: 1943 LKRKNQTLQDESQRNAKELWNAK-----ARLNNVMSKNINLESQNRSLKAEL 1803
            L ++N+ L+ +     K L   +        + ++ +N  L+ QN +LK  L
Sbjct: 1040 LLKENEELKKKVDDLEKALGYPEDGKDHKSPSELIKENEELKKQNDALKRAL 1091


>ref|XP_003701630.1| PREDICTED: major antigen-like [Megachile rotundata]
          Length = 2226

 Score =  140 bits (354), Expect = 3e-30
 Identities = 180/884 (20%), Positives = 376/884 (42%), Gaps = 56/884 (6%)
 Frame = -3

Query: 3218 QKILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLM 3039
            Q +L+   AL+ +  E   K+    +E    L +A  N +  + L+S + + ++ ++ L 
Sbjct: 300  QDLLDQIAALKAELQEKDDKI----QELLNELRQAEINLLELNNLKSQLEELKSQLEDLE 355

Query: 3038 EQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKE------------------VSRLYE 2913
             + N L++E  +L+N+      I +SL+ ++  LK                   ++   E
Sbjct: 356  LERNQLLEELAKLQNELAHTNAIKESLEKQLEVLKNDNEKLLKELDNANEQLLALTNQLE 415

Query: 2912 EEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQN 2733
            EEK     L+EN    + + E    +++ +N  L  +  +    ++KL+E+ E    L  
Sbjct: 416  EEKAARNALEENLKNCQSELE----RLQKDNTNLRDQLEVAKGENNKLREDVEAAKRLAE 471

Query: 2732 DMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKET 2553
            + + ++      + E EEL     +L+ D + +K+AL+        +E ++  L+++   
Sbjct: 472  ENERLKAELEKMKKENEELMNLNNVLKSDYDSMKQALNN-------LEAEINRLQDELNK 524

Query: 2552 VSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQME 2373
              +E    +     +   L+    K ES K +L    EQ  +L+LE +KL  +L   ++E
Sbjct: 525  AEEERKALLDENSNIKKQLEEAIAKNESLKAELDNVGEQLNKLKLEKDKLQEALNDMKLE 584

Query: 2372 NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSAT------ 2211
            N  LK     +         ++ +++G  + +   D +   EL + K+   + T      
Sbjct: 585  NDALKQNVRNLQSDLDHARKEAEDLRGAGDALRAADKDKMSELQKIKDELNNLTSEKDRL 644

Query: 2210 -----DMKKVNSDAGAKVSGILEMLLPMK-------DDVFSLKEEV---LGNINSLRNDA 2076
                 D+K  N +   K+   ++ +  MK        ++  LK+E+   +  ++ L+++ 
Sbjct: 645  ANENMDLKARNGELEKKLKDAMDQVEQMKLENADLLTEIDRLKKELDKAVNEVDRLKSEI 704

Query: 2075 QMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNA 1896
              ++ A+++  +   +L  E +    E+ + +AE DA+Q       R+N TLQ+E     
Sbjct: 705  GSLKDAVDKCMEELEKLQTENQAVKTEIEKCKAERDALQ-------RENSTLQNEIDELR 757

Query: 1895 KELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVE 1716
            K+L + K  + N+M++   LE++N  LK EL+         ++E   +++E   L  +V+
Sbjct: 758  KQLNDCKTEIENLMAQKNQLETENNKLKEELN-------ACKQENEAIKAESEKLREQVQ 810

Query: 1715 NLK---SELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL----- 1560
            +L    S+L+   D+    L+  E  LG H++  +          +KL   +DEL     
Sbjct: 811  SLNDDLSKLRGQLDIAEQKLQELE-PLGDHLQKEN----------DKLQNEIDELRKQLN 859

Query: 1559 -ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDS 1383
                 NEN K +   L   ++  R+ ++  + E  ++        G   + + Q+  +D 
Sbjct: 860  DCRTENENLKAQKNQLEAENNKLREELNACKQENEAM-----KAEGEKLRGQVQSLNDD- 913

Query: 1382 SGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXX 1203
              ++ L+N   +L+   +K+ E   + +   +E  ++ N+++E+++ L+D          
Sbjct: 914  --LNKLRN---QLDIAERKIEELEPLGDRLQKENDKLQNEIDELRKQLND---CRTENEN 965

Query: 1202 XXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXX 1023
               +   L+ EN +LR E+      + + K  EG  ++E           +Q        
Sbjct: 966  LKAQKNQLEAENNKLREELNACKQENEAMK-AEGEKLRE----------QVQSLNDEVSK 1014

Query: 1022 XXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXX 843
               ++D    + QE++ L+D             K+   LQN ++ L+             
Sbjct: 1015 LRNQLDIAERKIQELEPLVD----------RLQKENDKLQNDLKALEDDARNLRLRLD-- 1062

Query: 842  XXKWGGI--------DMNSIEKQLKELNIHVMQLVEHNTRLKKD 735
                GG+        DM  +E Q+ +LN  +      N  L+++
Sbjct: 1063 ----GGMSDNERMRNDMAMLESQVGDLNEKLKAAKAENDALQQE 1102



 Score =  115 bits (289), Expect = 9e-23
 Identities = 182/910 (20%), Positives = 376/910 (41%), Gaps = 90/910 (9%)
 Frame = -3

Query: 3194 ALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNALVK 3015
            ALQ++   LQ ++    +E  K L +  +  I   + +   ++ E +  +L E++NA  +
Sbjct: 741  ALQRENSTLQNEI----DELRKQLNDC-KTEIENLMAQKNQLETENN--KLKEELNACKQ 793

Query: 3014 EKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNALRQKNEDICLK 2835
            E   ++ ++++  E  QSL D++ +L+    + E++ Q   EL+   + L+++N+ +  +
Sbjct: 794  ENEAIKAESEKLREQVQSLNDDLSKLRGQLDIAEQKLQ---ELEPLGDHLQKENDKLQNE 850

Query: 2834 IEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLL 2655
            I+     L         L  +  + E + + L+ ++ + +Q +   + E E+L  Q+  L
Sbjct: 851  IDELRKQLNDCRTENENLKAQKNQLEAENNKLREELNACKQENEAMKAEGEKLRGQVQSL 910

Query: 2654 RDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKE 2475
             DD+N L+  L +A       E+++++LE   + + KE         KL +++  L ++ 
Sbjct: 911  NDDLNKLRNQLDIA-------ERKIEELEPLGDRLQKE-------NDKLQNEIDELRKQL 956

Query: 2474 ESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQ 2295
               + +      Q  QLE E  KL   L   + EN  +K   EK+ +  + L  +  +++
Sbjct: 957  NDCRTENENLKAQKNQLEAENNKLREELNACKQENEAMKAEGEKLREQVQSLNDEVSKLR 1016

Query: 2294 GQQEGILKQDINIEDELART-KEVGRSATDMKKVNSDAG---AKVSGILEMLLPMKDDVF 2127
             Q +   ++   +E  + R  KE  +   D+K +  DA     ++ G +     M++D+ 
Sbjct: 1017 NQLDIAERKIQELEPLVDRLQKENDKLQNDLKALEDDARNLRLRLDGGMSDNERMRNDMA 1076

Query: 2126 SLKEEVLGNINSLRNDAQMVQVALEQMQDTKS----ELFAEAEIRAQEVLRLQAEVDAIQ 1959
             L+ +V G++N     A+    AL+Q   T      ++  E     QE   L+AE+  + 
Sbjct: 1077 MLESQV-GDLNEKLKAAKAENDALQQENQTLRAKLLDMDNELSQAKQECADLKAEIADLN 1135

Query: 1958 HILIELKRKNQTLQDESQR----NAK---ELWNAKARLNNVMSKNINLESQNRSLKAELH 1800
            +++ EL+ K   L+++ +     N K   E+   KA L   +      ++  ++ +AEL+
Sbjct: 1136 NLISELRAKIAKLEEDVEHWKLENCKLQIEIDKLKADLEKALKDLSECQALKKAQEAELN 1195

Query: 1799 -LQAQKA----------FQIQEERNVVESEH-----------------NVLSSEVENLKS 1704
             LQ +KA           QI+E++   E E                  N L  E+E L+ 
Sbjct: 1196 RLQNEKAELNKQIAGLTAQIEEQKKAAELEKSAKGESEAKLKALQDELNALKKELEKLRM 1255

Query: 1703 ELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKN 1524
            E  + K+      R    L  Q ++    +I + R   + L   L+ L  L++E  KLK 
Sbjct: 1256 ENNDYKNEMDNMKRQLSALNSQ-LDSCKEEIAALRATNDSLKTELNALSGLKDEYDKLKA 1314

Query: 1523 EA----------------LYEYHDYERKNVSGSRAEA---MSVLISKSLGNGRAN----- 1416
            +                 L +  +  R    G R E     S L ++    G+       
Sbjct: 1315 KVNSLENEIAGLQENARNLEQERNKLRGEGDGQRIEIDKLKSALDAEKAAAGKLRSDLES 1374

Query: 1415 -QREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSR-----------EAQQM 1272
             Q E          ++  K++  RL  ++ +L++     E K++           E QQ+
Sbjct: 1375 CQTENDRLRAQLKDLEKCKSEIDRLNAEIDQLNKALAAAEAKAKSLEDQLSNLQDEKQQL 1434

Query: 1271 ANKLEEMQQTLSDMXXXXXXXXXXXIR-----------VRSLKKENTRLRSEMKGELTPS 1125
             N+L  ++  LS++            +           + +LK    ++R+E +  L  +
Sbjct: 1435 INELNNLRGDLSNLRNELEKQTAAKDKALKELADAKEELNALKATLNKMRNENETLLNEN 1494

Query: 1124 RSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYW 945
               K +      ++     ++  L +                   T E+ T+ +  ++  
Sbjct: 1495 EKLKSKVTELNGQLEASRNENEKLKKENENLKNEVAKL-------TSELATMTNKLKEAE 1547

Query: 944  NRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQL 765
            +R++    +  +L+N++ +L++                    +N ++ +L ELN  +  L
Sbjct: 1548 DRLNALKNENDTLKNTIDKLEKAIKELEAVKMQLEQA-----LNELKPKLAELNEQLEAL 1602

Query: 764  VEHNTRLKKD 735
               N +LKK+
Sbjct: 1603 RNENEKLKKE 1612



 Score =  108 bits (271), Expect = 1e-20
 Identities = 187/872 (21%), Positives = 368/872 (42%), Gaps = 101/872 (11%)
 Frame = -3

Query: 3191 LQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNALVKE 3012
            LQK+  +LQ ++    +E  K L +    +     L++     EA   +L E++NA  +E
Sbjct: 938  LQKENDKLQNEI----DELRKQLNDCRTEN---ENLKAQKNQLEAENNKLREELNACKQE 990

Query: 3011 KRELENDAQRGEEISQSLKDEVFQLK-----------EVSRLYEEEKQHTIELQENFNAL 2865
               ++ + ++  E  QSL DEV +L+           E+  L +  ++   +LQ +  AL
Sbjct: 991  NEAMKAEGEKLREQVQSLNDEVSKLRNQLDIAERKIQELEPLVDRLQKENDKLQNDLKAL 1050

Query: 2864 RQKNEDICLKIEAN-------NNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSV---- 2718
                 ++ L+++          N +   ++ + +L+ KL+  + +  ALQ + Q++    
Sbjct: 1051 EDDARNLRLRLDGGMSDNERMRNDMAMLESQVGDLNEKLKAAKAENDALQQENQTLRAKL 1110

Query: 2717 -EQMHAVSQTERE----------------ELNRQLVLLRDDVNH--------------LK 2631
             +  + +SQ ++E                EL  ++  L +DV H              LK
Sbjct: 1111 LDMDNELSQAKQECADLKAEIADLNNLISELRAKIAKLEEDVEHWKLENCKLQIEIDKLK 1170

Query: 2630 EALSMAVDD-------RAFMEKQLQDLENQKETVSKELALSVSR--EQKLASDLKALSEK 2478
              L  A+ D       +   E +L  L+N+K  ++K++A   ++  EQK A++L+  S K
Sbjct: 1171 ADLEKALKDLSECQALKKAQEAELNRLQNEKAELNKQIAGLTAQIEEQKKAAELEK-SAK 1229

Query: 2477 EESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREV 2298
             ES      +Q E N  L+ E+EKL       +MEN   K+  + +      L ++    
Sbjct: 1230 GESEAKLKALQDELNA-LKKELEKL-------RMENNDYKNEMDNMKRQLSALNSQLDSC 1281

Query: 2297 QGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLK 2118
            + +   +   + +++ EL        + + +K       AKV+ +   +  ++++  +L+
Sbjct: 1282 KEEIAALRATNDSLKTEL-------NALSGLKDEYDKLKAKVNSLENEIAGLQENARNLE 1334

Query: 2117 EE---VLGNINSLRNDAQMVQVALEQMQDTKSELFAEAE--------IRAQ--------- 1998
            +E   + G  +  R +   ++ AL+  +    +L ++ E        +RAQ         
Sbjct: 1335 QERNKLRGEGDGQRIEIDKLKSALDAEKAAAGKLRSDLESCQTENDRLRAQLKDLEKCKS 1394

Query: 1997 EVLRLQAEVDAIQHIL--IELKRKN-----QTLQDESQRNAKELWNAKARLNNVMSK-NI 1842
            E+ RL AE+D +   L   E K K+       LQDE Q+   EL N +  L+N+ ++   
Sbjct: 1395 EIDRLNAEIDQLNKALAAAEAKAKSLEDQLSNLQDEKQQLINELNNLRGDLSNLRNELEK 1454

Query: 1841 NLESQNRSLK----AELHLQAQKAF--QIQEERNVVESEHNVLSSEVENLKSELKESKDL 1680
               +++++LK    A+  L A KA   +++ E   + +E+  L S+V  L  +L+ S++ 
Sbjct: 1455 QTAAKDKALKELADAKEELNALKATLNKMRNENETLLNENEKLKSKVTELNGQLEASRNE 1514

Query: 1679 EGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEA-LYEYH 1503
                 +  E L     EVA L  E       KL    D L  L+NEN  LKN     E  
Sbjct: 1515 NEKLKKENENLKN---EVAKLTSELATMT-NKLKEAEDRLNALKNENDTLKNTIDKLEKA 1570

Query: 1502 DYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQV--- 1332
              E + V     +A++ L  K        +      E+     ++LKN+ T+L  ++   
Sbjct: 1571 IKELEAVKMQLEQALNELKPKLAELNEQLEALRNENEKLKKENEVLKNEKTKLTLELDAM 1630

Query: 1331 -QKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLR 1155
              KL E  +       E   + N + + Q+ + ++             ++ LK EN  L+
Sbjct: 1631 TNKLKEAEDRLNALKNENDTLKNTIAQQQKAIKEL---EAAKIQLEQAMKELKSENEGLK 1687

Query: 1154 SEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEID 975
             +++     +   K+ +   +K  N   +D+   ++               R    +E +
Sbjct: 1688 DKLEDAQNKANKLKN-DLDKLKRDNAKLQDELGKLKEEKEKADAAAKGDADRIK--KENE 1744

Query: 974  TLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQ 879
             L  +N K  + ++    + + L+  +++LQ+
Sbjct: 1745 KLRAENAKLMDELNTCRAENEELRKQLEKLQE 1776



 Score = 84.7 bits (208), Expect = 2e-13
 Identities = 194/967 (20%), Positives = 377/967 (38%), Gaps = 161/967 (16%)
 Frame = -3

Query: 2996 NDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNALRQK------NEDICLK 2835
            +D  +  EI   L   V +L+ +    ++ +   ++L+    +L+Q       NED  LK
Sbjct: 39   SDDSKESEI-YDLSFAVRKLRVMKCQMKKWRMERLQLESENRSLKQALQSFGVNEDEILK 97

Query: 2834 IEA----NNNLLEQKDNIIVELSHKLQENEE---QRSALQNDMQSVEQMHAVSQTEREEL 2676
             +     +   +E+  +    L  K+++ EE   +R    +   SV  +    +  RE  
Sbjct: 98   PDPLLIHSREEIERLQSTNATLEDKVRDLEETLAERDCCDDPCASVLCLREKMRYLRERF 157

Query: 2675 NRQLVLLRDDVNHLKEALSMAVDD-------------RAFME------KQLQDLENQKET 2553
              +   LRD ++HLK  L+   +D             RA M+      K   DL+ + + 
Sbjct: 158  ALEKKELRDMISHLKLKLAETEEDVSCPAIYRLRAKLRALMKGGLDVPKNCDDLQAENDR 217

Query: 2552 VSKELA-----LSVSREQKLAS-----------------DLKALSEKEESTKNQLLIQTE 2439
            +  E+A     L+   E+++                   D+  L ++ +  +N +   T+
Sbjct: 218  LLAEIAELKRQLAKLDEKEITGHTSPAKSVETTTVPEYIDVSDLLQRLKDCENTVAGLTQ 277

Query: 2438 QNKQLELEIEKLYGSLQMKQMENTL----------LKDGNEKIYDL-------------- 2331
            Q  + +  I+ L  +L+    +  L          L++ ++KI +L              
Sbjct: 278  QLAEKDNLIDSLNNALEGTISQQDLLDQIAALKAELQEKDDKIQELLNELRQAEINLLEL 337

Query: 2330 ------CKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATD----MKKVNSDAG 2181
                   + L ++  +++ ++  +L++   +++ELA T  +  S       +K  N    
Sbjct: 338  NNLKSQLEELKSQLEDLELERNQLLEELAKLQNELAHTNAIKESLEKQLEVLKNDNEKLL 397

Query: 2180 AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIR- 2004
             ++    E LL + + +    EE     N+L  + +  Q  LE++Q   + L  + E+  
Sbjct: 398  KELDNANEQLLALTNQL----EEEKAARNALEENLKNCQSELERLQKDNTNLRDQLEVAK 453

Query: 2003 ----------------AQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKA 1872
                            A+E  RL+AE++ ++    EL   N  L+ +     + L N +A
Sbjct: 454  GENNKLREDVEAAKRLAEENERLKAELEKMKKENEELMNLNNVLKSDYDSMKQALNNLEA 513

Query: 1871 RLNN--------------VMSKNINLESQ-------NRSLKAEL--------HLQAQKAF 1779
             +N               ++ +N N++ Q       N SLKAEL         L+ +K  
Sbjct: 514  EINRLQDELNKAEEERKALLDENSNIKKQLEEAIAKNESLKAELDNVGEQLNKLKLEKD- 572

Query: 1778 QIQEERNVVESEHNVLSSEVENLKSEL----KESKDLEGYFLRLFEILLGQHVEVASLDI 1611
            ++QE  N ++ E++ L   V NL+S+L    KE++DL G          G  +  A  D 
Sbjct: 573  KLQEALNDMKLENDALKQNVRNLQSDLDHARKEAEDLRG---------AGDALRAADKDK 623

Query: 1610 ESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKN--VSGSRAEAMSVLISKS 1437
             S      +L +I DEL  L +E  +L NE +    D + +N  +     +AM  +    
Sbjct: 624  MS------ELQKIKDELNNLTSEKDRLANENM----DLKARNGELEKKLKDAMDQVEQMK 673

Query: 1436 LGNG-RANQREFQNKEEDS--SGVDLLKNKCTRLEFQVQKLSEKAEMFETKS-------- 1290
            L N     + +   KE D   + VD LK++   L+  V K  E+ E  +T++        
Sbjct: 674  LENADLLTEIDRLKKELDKAVNEVDRLKSEIGSLKDAVDKCMEELEKLQTENQAVKTEIE 733

Query: 1289 ----------REAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKG 1140
                      RE   + N+++E+++ L+D             +   L+ EN +L+ E+  
Sbjct: 734  KCKAERDALQRENSTLQNEIDELRKQLND---CKTEIENLMAQKNQLETENNKLKEELNA 790

Query: 1139 ELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDD 960
                + + K       +++   ++D + L             ++D    + QE++ L D 
Sbjct: 791  CKQENEAIKAESEKLREQVQSLNDDLSKL-----------RGQLDIAEQKLQELEPLGD- 838

Query: 959  NRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNI 780
                     H  K+   LQN + EL++                    +N    + + L  
Sbjct: 839  ---------HLQKENDKLQNEIDELRK-------------------QLNDCRTENENLKA 870

Query: 779  HVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEEVPILCHQNSKIAERLDINT 600
               QL   N +L++++    A       +  + +KL+   +V  L    +K+  +LDI  
Sbjct: 871  QKNQLEAENNKLREELN---ACKQENEAMKAEGEKLR--GQVQSLNDDLNKLRNQLDIAE 925

Query: 599  DKARALD 579
             K   L+
Sbjct: 926  RKIEELE 932


>ref|XP_653447.1| Viral A-type inclusion protein repeat [Entamoeba histolytica
            HM-1:IMSS] gi|56470397|gb|EAL48061.1| Viral A-type
            inclusion protein repeat, putative [Entamoeba histolytica
            HM-1:IMSS]
          Length = 1813

 Score =  139 bits (349), Expect = 1e-29
 Identities = 181/952 (19%), Positives = 390/952 (40%), Gaps = 58/952 (6%)
 Frame = -3

Query: 3224 QHQKILEDYYAL----QKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREA 3057
            +++KI+ +   L    ++K  EL+ +V   EEE  K +TE        S L   +   + 
Sbjct: 311  ENEKIMNELSQLKQEKEEKENELKEQVKKMEEEKSKLITELSNGSDGISKLNEELTQTKQ 370

Query: 3056 HIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQL----KEVSRLYEEEKQHTIE 2889
              +++  ++N++ +EK+ +E +  +    ++ +K+E  ++    KE+ +  E+EK+   +
Sbjct: 371  EKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQ 430

Query: 2888 LQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQM 2709
            LQ   N ++ + ++I           E+   II + + ++ + +E++  LQ ++  +++ 
Sbjct: 431  LQNEINTIQTRMKEI----------EEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEE 480

Query: 2708 HAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQD-------LENQKETV 2550
               ++ E+ EL        +++N LKE      +++  +E  L         L  +KE++
Sbjct: 481  KQKTENEKNELVDVKTQKENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESI 540

Query: 2549 ------------SKELALSVSREQK--LASDLKALSEKEESTKNQLLIQTEQNKQLELEI 2412
                        +KEL ++   E+K  L +D   + +++E+ + +L     +  Q E E+
Sbjct: 541  KQELDSIKADNSTKELEINKINEEKNQLQNDYDTVQQEKENIQKELNQIKIEKSQKEEEL 600

Query: 2411 EKLYGSLQMKQMENTLL-------KDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIE 2253
             K+    Q  + E   L        DG  K+ ++   L  +   +  +   I  +  NI 
Sbjct: 601  NKIKEEKQQVEDEKAKLITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNIS 660

Query: 2252 DELARTK-EVGRSATDMKKVNSDAGA---KVSGILEMLLPMKDDVFSLKEEVLGNINSLR 2085
            +E  +TK E+ +   +  ++N +      +++ I E    ++D+   +++E    I  L 
Sbjct: 661  NEFNKTKEEIKQKENETIQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQEKENEITKLN 720

Query: 2084 NDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKN---QTLQD 1914
             D  +++  L Q++  K E+  E      E  +++   D    ++ EL   N     L +
Sbjct: 721  EDKTVIENELNQIKTEKQEIENELNQTKDEKQKIE---DEKSKLITELSNGNDGISKLNE 777

Query: 1913 ESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERN----VVES 1746
            E  +  +E  N    LN + ++  + + QN   + EL  +  K  Q  E++N     +E 
Sbjct: 778  ELTQTKQEKENVLNELNQIKNEFASFKEQNTQKENELKDENNKVQQELEQKNNEVSKLEE 837

Query: 1745 EHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILD 1566
            E   +S+E+ N K EL++ K                                        
Sbjct: 838  EKGNISNELSNTKQELEQKK---------------------------------------Q 858

Query: 1565 ELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQ---REFQNK 1395
            E+I +  E  + +NE   +      K +   +++ ++ L + S G  + N+   +  Q K
Sbjct: 859  EIITITQEKEEKENELKEQV-----KKIEEEKSKLITELSNGSDGISKLNEELTQTKQEK 913

Query: 1394 EEDSSGVDLLKNKCTRLEFQVQKLSE-KAEMFETKSREAQQMAN---KLEEMQQTLSDMX 1227
            EE    ++  K K  R+E +++++ E K E+ E K++  ++  N   +L E ++ + ++ 
Sbjct: 914  EEIQKALEEEKEKLERIETELKEIKEAKQELEEEKNKTIEEKTNLQQELNENKKIVEELT 973

Query: 1226 XXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQ 1047
                        + S+K+E  R+  E    +  ++  K      IK I    ++   L  
Sbjct: 974  QTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEN---IKSIEEKTQEINSLTT 1030

Query: 1046 XXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXX 867
                           R    +E D ++ +      +     KQ +   N + E+Q+    
Sbjct: 1031 SIEELKGRLEESKGERIEIEKERDRVISELNDIKLQNEGMKKQVEEAHNRMTEMQKSFEG 1090

Query: 866  XXXXXXXXXXKWGGIDMNSIEKQLKELNIHVM----QLVEHNTRLKKDVKFGFAWANSMH 699
                            +  + ++ K++N  VM    QL + N  L++  K      N   
Sbjct: 1091 SENEMINSLNN----QITQLNEKEKQMNEQVMALQTQLSQSNINLEEVKKDLIESQNKYT 1146

Query: 698  DLNGQEQKLKVDEEVPILCHQNSKIAERLDINTDKARALDMEVQRIRLILSR 543
             +N  E+K  V++E   +  +   + E L+ N  +   L  +     L L++
Sbjct: 1147 QIN--EEKDCVEQERNKINEEYKTVNEELEKNKKELNDLQTKYDNEILELNK 1196



 Score =  126 bits (316), Expect = 7e-26
 Identities = 183/973 (18%), Positives = 399/973 (41%), Gaps = 95/973 (9%)
 Frame = -3

Query: 3191 LQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNALVKE 3012
            +QK+  +++ +   +EEE  K   E  +     + L + + +    + +L E ++ L  E
Sbjct: 582  IQKELNQIKIEKSQKEEELNKIKEEKQQVEDEKAKLITDIANGNDGLTKLNEVIDKLKDE 641

Query: 3011 KRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNALRQKNEDICLKI 2832
            K  + N+  + +    ++ +E  + KE             E+++  N   Q NE+  + +
Sbjct: 642  KENISNELNQIKNERDNISNEFNKTKE-------------EIKQKENETIQLNEEKSVLL 688

Query: 2831 EANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLR 2652
               N + E+K  I  E +   QE E + + L  D   +E      +TE++E+  +L   +
Sbjct: 689  NELNQIKEEKQKIEDEKAVIQQEKENEITKLNEDKTVIENELNQIKTEKQEIENELNQTK 748

Query: 2651 DDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSK---ELALSVSREQKLASDLKALSE 2481
            D+   +++  S          K + +L N  + +SK   EL  +   ++ + ++L  +  
Sbjct: 749  DEKQKIEDEKS----------KLITELSNGNDGISKLNEELTQTKQEKENVLNELNQIKN 798

Query: 2480 KEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSRE 2301
            +  S K Q    T++  +L+ E  K+   L+ K  E + L++    I +  +L  TK   
Sbjct: 799  EFASFKEQ---NTQKENELKDENNKVQQELEQKNNEVSKLEEEKGNISN--ELSNTKQEL 853

Query: 2300 VQGQQE--GILKQDINIEDEL-ARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDV 2130
             Q +QE   I ++    E+EL  + K++    + +    S+    +S + E L   K + 
Sbjct: 854  EQKKQEIITITQEKEEKENELKEQVKKIEEEKSKLITELSNGSDGISKLNEELTQTKQE- 912

Query: 2129 FSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHIL 1950
               KEE+   +   +   + ++  L+++++ K EL  E     +E   LQ E++  + I+
Sbjct: 913  ---KEEIQKALEEEKEKLERIETELKEIKEAKQELEEEKNKTIEEKTNLQQELNENKKIV 969

Query: 1949 IEL---KRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQN--------------- 1824
             EL   K++ + + +E     +E    +   N ++++N  ++ +N               
Sbjct: 970  EELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEENIKSIEEKTQEINSLT 1029

Query: 1823 ---RSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKES--------KDLE 1677
                 LK  L     +  +I++ER+ V SE N +  + E +K +++E+        K  E
Sbjct: 1030 TSIEELKGRLEESKGERIEIEKERDRVISELNDIKLQNEGMKKQVEEAHNRMTEMQKSFE 1089

Query: 1676 GYFLRLFEILLGQHVEV--------------------ASLDIESCR----FAEEKLMRIL 1569
            G    +   L  Q  ++                    +++++E  +     ++ K  +I 
Sbjct: 1090 GSENEMINSLNNQITQLNEKEKQMNEQVMALQTQLSQSNINLEEVKKDLIESQNKYTQIN 1149

Query: 1568 DELICLRNENAKLKNE--ALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNK 1395
            +E  C+  E  K+  E   + E  +  +K ++  + +  + ++  +           +NK
Sbjct: 1150 EEKDCVEQERNKINEEYKTVNEELEKNKKELNDLQTKYDNEILELN-----------KNK 1198

Query: 1394 EEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKL-EEMQQTLSDMXXXX 1218
            +E +S ++ LK + T LE QV+K+ E+     T+        +KL EE+ QT  +     
Sbjct: 1199 DELNSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNGSDGVSKLNEELTQTKQEKEEIN 1258

Query: 1217 XXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXX 1038
                      + +++E  ++ +E K         +  +   +KEI    E +  L     
Sbjct: 1259 NELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQL----- 1313

Query: 1037 XXXXXXXXKIDTRTSETQEID-TLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXX 861
                     I TR  E +E +  ++ DN K    ++ F ++ ++LQ  + ++++      
Sbjct: 1314 ---QNEINTIQTRMKEIEEKNQEIICDNNK---EIAKFKEEQENLQKELNQIKEEKSKLI 1367

Query: 860  XXXXXXXXKWGGI-----------------------DMNSIEKQLKELNIHVMQLVEHNT 750
                        +                       + N I+ +L++ N  + ++ E   
Sbjct: 1368 TDLSNGNDGLSKLNEEIETINKEKEGIRKELESLKEENNKIQDELEQKNQELSKVKEEKE 1427

Query: 749  RLKKDVKFGFAWANSMH-DLNG--------QEQKLKVDEEVPILCHQNSKIAERLDINTD 597
            +L  D+  G    N ++ DLN          E+ +++  E+  L  +N +++  L    +
Sbjct: 1428 KLIHDLTNGNDGINQLNEDLNQIKNDKEELTEKNVQLQNEINKLKSENEELSNNLSFEKE 1487

Query: 596  KARALDMEVQRIR 558
              + ++ EV  I+
Sbjct: 1488 GLKQVNEEVNAIK 1500



 Score =  122 bits (306), Expect = 1e-24
 Identities = 176/923 (19%), Positives = 370/923 (40%), Gaps = 69/923 (7%)
 Frame = -3

Query: 3218 QKILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLM 3039
            Q+I+      ++K  EL+ +V   EEE  K +TE L N   G             I +L 
Sbjct: 858  QEIITITQEKEEKENELKEQVKKIEEEKSKLITE-LSNGSDG-------------ISKLN 903

Query: 3038 EQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNALRQ 2859
            E++    +EK E++   +  +E  + ++ E+ ++KE  +  EEEK  TIE + N      
Sbjct: 904  EELTQTKQEKEEIQKALEEEKEKLERIETELKEIKEAKQELEEEKNKTIEEKTNLQQELN 963

Query: 2858 KNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREE 2679
            +N+ I  ++       E+ +N +  +  + +  EE+++ + N+ + +++ +  S    EE
Sbjct: 964  ENKKIVEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEENIKS---IEE 1020

Query: 2678 LNRQLVLLRDDVNHLKEALSMAVDDRAFMEK-------QLQDLENQKETVSKELALSVSR 2520
              +++  L   +  LK  L  +  +R  +EK       +L D++ Q E + K++  + +R
Sbjct: 1021 KTQEINSLTTSIEELKGRLEESKGERIEIEKERDRVISELNDIKLQNEGMKKQVEEAHNR 1080

Query: 2519 EQKLASDLKALSEKE--ESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNE 2346
              ++    +  SE E   S  NQ+    E+ KQ+  ++  L           T L   N 
Sbjct: 1081 MTEMQKSFEG-SENEMINSLNNQITQLNEKEKQMNEQVMAL----------QTQLSQSNI 1129

Query: 2345 KIYDLCK-LLATKSREVQ-GQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKV 2172
             + ++ K L+ ++++  Q  +++  ++Q+ N  +E    K V       KK  +D   K 
Sbjct: 1130 NLEEVKKDLIESQNKYTQINEEKDCVEQERNKINE--EYKTVNEELEKNKKELNDLQTKY 1187

Query: 2171 SGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEV 1992
               +  L   KD++ SL       IN+L+ +   ++  +++M++ KS+L  E    +  V
Sbjct: 1188 DNEILELNKNKDELNSL-------INNLKEEKTNLEEQVKKMEEEKSKLITELSNGSDGV 1240

Query: 1991 LRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLK 1812
             +L  E+   +    E+  +  ++++E +R  +E          +  +   +E + + L 
Sbjct: 1241 SKLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELL 1300

Query: 1811 AELHLQAQKAFQIQEERNVVES------------------EHNVLSSEVENLKSELKESK 1686
             E+  + +   Q+Q E N +++                  E      E ENL+ EL + K
Sbjct: 1301 KEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIK 1360

Query: 1685 DLEGYFLRLFE------ILLGQHVEVASLDIESCRFAEEKLM----RILDELICLRNENA 1536
            + +   +            L + +E  + + E  R   E L     +I DEL     E +
Sbjct: 1361 EEKSKLITDLSNGNDGLSKLNEEIETINKEKEGIRKELESLKEENNKIQDELEQKNQELS 1420

Query: 1535 KLKNEALYEYHDYERKN------------VSGSRAE--AMSVLISKSLGNGRANQREFQN 1398
            K+K E     HD    N            +   + E    +V +   +   ++   E  N
Sbjct: 1421 KVKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDKEELTEKNVQLQNEINKLKSENEELSN 1480

Query: 1397 K--------EEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETK--------SREAQQMAN 1266
                     ++ +  V+ +K +   L  Q++K+ E+    E +        + +  Q+ N
Sbjct: 1481 NLSFEKEGLKQVNEEVNAIKEERDELVKQIKKIEEEKRKVEEELNFNGSEVNEQIAQINN 1540

Query: 1265 KLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKE 1086
            + E++ Q  +++             +   K+ N   + E   EL    + K  +   +KE
Sbjct: 1541 EKEQLNQECNELKQNLKELQSKIEEIEQEKESNEIKKKEELQELQEEITEKDNDIKNLKE 1600

Query: 1085 INIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSL 906
                       I+            ++  ++ T+E++ L +   +    +    K+ +S+
Sbjct: 1601 ----------EIERIEKELQEKEEDMEQMSNNTEELEELKNKLTETQRLLEEEKKEKESI 1650

Query: 905  QNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKF 726
             N  +E ++                   +MN + +  +E      +L EH  +LK  ++ 
Sbjct: 1651 SNEFEETKEQVLVELQRVNN--------EMNKMNEIKQEDENEKEELQEHINKLKSQIER 1702

Query: 725  GFAWANSMHDLNGQEQKLKVDEE 657
                   +  L  +  +LK + E
Sbjct: 1703 ENEQLKEVSKLKWELSELKTENE 1725



 Score =  121 bits (304), Expect = 2e-24
 Identities = 167/948 (17%), Positives = 406/948 (42%), Gaps = 63/948 (6%)
 Frame = -3

Query: 3194 ALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNA--- 3024
            A +  A E+   V+ + EE  K L    E      L + C         ++  +M A   
Sbjct: 166  ASETTAEEVNRSVNAQIEEENKRLQNENEE-----LKKKCDAQDSLLKTKMKSEMEAKKK 220

Query: 3023 ---LVKEKRELENDAQRGEEISQSLKDEVFQLK--------EVSRLYEEEKQHTIEL--- 2886
               L  EK++L +      +    L +E+ Q+K        E+ +  +E++    EL   
Sbjct: 221  VEILENEKKDLIDKMANENDGMSKLNEELTQIKNEKESINNELIQTKQEKESINNELTQL 280

Query: 2885 -------QENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDM 2727
                   +   N +R + +++   IE  N   E+ + I+ ELS   QE EE+ + L+  +
Sbjct: 281  KTDNDQKENELNQVRHEKDEV---IEKFNTSKEENEKIMNELSQLKQEKEEKENELKEQV 337

Query: 2726 QSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVS 2547
            + +E+       E+ +L  +L    D ++ L E L+    ++  +  +L  ++ +K+ + 
Sbjct: 338  KKMEE-------EKSKLITELSNGSDGISKLNEELTQTKQEKEEINNELNSIKEEKKRIE 390

Query: 2546 KELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENT 2367
            +E    ++  +++  + + + E+++    ++  + E N QL+ EI  +    +MK++E  
Sbjct: 391  EEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTI--QTRMKEIE-- 446

Query: 2366 LLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSD 2187
              +   E I D  K +A    + + +QE + K+   I++E  +T+       D+K    +
Sbjct: 447  --EKNQEIICDNNKEIA----KFKEEQENLQKELNQIKEEKQKTENEKNELVDVKTQKEN 500

Query: 2186 AGAK--------------VSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQ 2049
               K              +   L  ++  K+ +   KE +   ++S++ D    ++ + +
Sbjct: 501  ELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIKADNSTKELEINK 560

Query: 2048 MQDTKSELFAEAEIRAQEVLRLQAEVDAI-------QHILIELKRKNQTLQDESQRNAKE 1890
            + + K++L  + +   QE   +Q E++ I       +  L ++K + Q ++DE  +   +
Sbjct: 561  INEEKNQLQNDYDTVQQEKENIQKELNQIKIEKSQKEEELNKIKEEKQQVEDEKAKLITD 620

Query: 1889 LWNAK---ARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEV 1719
            + N      +LN V+ K   L+ +  ++  EL+       QI+ ER+ + +E N    E+
Sbjct: 621  IANGNDGLTKLNEVIDK---LKDEKENISNELN-------QIKNERDNISNEFNKTKEEI 670

Query: 1718 ENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNEN 1539
            +  ++E  +  + +   L     +  +  ++        +  E ++ ++ ++   + NE 
Sbjct: 671  KQKENETIQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQEKENEITKLNEDKTVIENEL 730

Query: 1538 AKLKNE------ALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSG 1377
             ++K E       L +  D E++ +   +++ ++ L + + G  + N+   Q K+E  + 
Sbjct: 731  NQIKTEKQEIENELNQTKD-EKQKIEDEKSKLITELSNGNDGISKLNEELTQTKQEKENV 789

Query: 1376 VDLLKN-KCTRLEFQVQKLSEKAEMFETKSREAQQM------ANKLEEMQQTLS-DMXXX 1221
            ++ L   K     F+ Q   ++ E+ +  ++  Q++       +KLEE +  +S ++   
Sbjct: 790  LNELNQIKNEFASFKEQNTQKENELKDENNKVQQELEQKNNEVSKLEEEKGNISNELSNT 849

Query: 1220 XXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXX 1041
                      + ++ +E     +E+K ++   +  +  +   I E++ G +  + L +  
Sbjct: 850  KQELEQKKQEIITITQEKEEKENELKEQV---KKIEEEKSKLITELSNGSDGISKLNE-- 904

Query: 1040 XXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXX 861
                     ++     E +EI   +++ ++   R+    K+ +  +  ++E +       
Sbjct: 905  ---------ELTQTKQEKEEIQKALEEEKEKLERIETELKEIKEAKQELEEEKNKTIE-- 953

Query: 860  XXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNG-Q 684
                         +  +++++L E      ++VE  T+ K++ +         ++LN  +
Sbjct: 954  -------------EKTNLQQELNENK----KIVEELTQTKQEKE------EINNELNSIK 990

Query: 683  EQKLKVDEEVPILCHQNSKIAERLDINTDKARALDMEVQRIRLILSRI 540
            E+K +++EE      +N  I E  +I  +  ++++ + Q I  + + I
Sbjct: 991  EEKKRIEEE------KNQIINENKEIKEENIKSIEEKTQEINSLTTSI 1032



 Score =  102 bits (255), Expect = 8e-19
 Identities = 160/908 (17%), Positives = 382/908 (42%), Gaps = 78/908 (8%)
 Frame = -3

Query: 2996 NDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNN 2817
            ND+++ +  +Q   ++V Q K       E +  T EL       +  +E    + ++++ 
Sbjct: 62   NDSEQQDPPTQQPVEKVQQRKGFLSRRSETQSQTNELVSTPPHEKSGDEAKNEQKQSSSQ 121

Query: 2816 LLE--QKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVS----QTEREELNRQLVL- 2658
              E  +K+     LS   +++  +R++ +N   S  +  A S    +T  EE+NR +   
Sbjct: 122  TSESTEKETHKKRLSFLGRKSFSKRNSTENTGHSSSEHSATSSLASETTAEEVNRSVNAQ 181

Query: 2657 -------LRDDVNHLKEA-------LSMAVDDRAFMEKQLQDLENQKETVSKELALSVSR 2520
                   L+++   LK+        L   +      +K+++ LEN+K+ +  ++A     
Sbjct: 182  IEEENKRLQNENEELKKKCDAQDSLLKTKMKSEMEAKKKVEILENEKKDLIDKMANENDG 241

Query: 2519 EQKLASDLKALSEKEESTKNQLLIQTEQNKQ-LELEIEKLYGSLQMKQMENTLLKDGNEK 2343
              KL  +L  +  ++ES  N+ LIQT+Q K+ +  E+ +L      K+ E   ++   ++
Sbjct: 242  MSKLNEELTQIKNEKESINNE-LIQTKQEKESINNELTQLKTDNDQKENELNQVRHEKDE 300

Query: 2342 IYDLCKLLATKSREVQGQQEGILKQDINIEDEL-ARTKEVGRSATDMKKVNSDAGAKVSG 2166
            + +       ++ ++  +   + ++    E+EL  + K++    + +    S+    +S 
Sbjct: 301  VIEKFNTSKEENEKIMNELSQLKQEKEEKENELKEQVKKMEEEKSKLITELSNGSDGISK 360

Query: 2165 ILEMLLPMKDDVFSLKEEVLGNINSLR--------------NDAQMVQVALEQMQDTKSE 2028
            + E L   K +    KEE+   +NS++              N+ + ++   E++++ K E
Sbjct: 361  LNEELTQTKQE----KEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKE 416

Query: 2027 LFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTL--------------QDESQRNAKE 1890
            L  E E   +   +LQ E++ IQ  + E++ KNQ +              Q+  Q+   +
Sbjct: 417  LLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQ 476

Query: 1889 LWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQ----IQEERNVVESEHNVLSSE 1722
            +   K +  N  ++ +++++Q  +   +L  + ++ F     I+   N +  E N L+ E
Sbjct: 477  IKEEKQKTENEKNELVDVKTQKENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEE 536

Query: 1721 VENLKSELKESK-DLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRN 1545
             E++K EL   K D     L + +I   +       D ++ +  +E + + L+++   ++
Sbjct: 537  KESIKQELDSIKADNSTKELEINKI--NEEKNQLQNDYDTVQQEKENIQKELNQIKIEKS 594

Query: 1544 ENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQ---REFQNKEEDSSGV 1374
            +    K E L +  + E++ V   +A+ ++ + + + G  + N+   +    KE  S+ +
Sbjct: 595  Q----KEEELNKIKE-EKQQVEDEKAKLITDIANGNDGLTKLNEVIDKLKDEKENISNEL 649

Query: 1373 DLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQ-------MANKLEEMQQTLSDMXXXXX 1215
            + +KN+   +  +  K  E+ +  E ++ +  +         N+++E +Q + D      
Sbjct: 650  NQIKNERDNISNEFNKTKEEIKQKENETIQLNEEKSVLLNELNQIKEEKQKIED--EKAV 707

Query: 1214 XXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXX 1035
                    +  L ++ T + +E+    T  +  ++       E    +++ + LI     
Sbjct: 708  IQQEKENEITKLNEDKTVIENELNQIKTEKQEIENELNQTKDEKQKIEDEKSKLITELSN 767

Query: 1034 XXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXX 855
                     +  T   QE + ++++  +  N  + F +Q    +N +++           
Sbjct: 768  GNDGISKLNEELTQTKQEKENVLNELNQIKNEFASFKEQNTQKENELKD----------- 816

Query: 854  XXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQK 675
                       + N ++++L++ N  V +L E    +  ++      +N+  +L  ++Q+
Sbjct: 817  -----------ENNKVQQELEQKNNEVSKLEEEKGNISNEL------SNTKQELEQKKQE 859

Query: 674  L------------KVDEEVPILCHQNSKIAERLDINTDKARALDMEVQRIRLILSRIPTK 531
            +            ++ E+V  +  + SK+   L   +D    L+ E+ + +     I   
Sbjct: 860  IITITQEKEEKENELKEQVKKIEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEIQKA 919

Query: 530  PTEEASKM 507
              EE  K+
Sbjct: 920  LEEEKEKL 927


>ref|XP_001582404.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
            gi|121916639|gb|EAY21418.1| viral A-type inclusion
            protein, putative [Trichomonas vaginalis G3]
          Length = 2120

 Score =  138 bits (347), Expect = 2e-29
 Identities = 175/829 (21%), Positives = 363/829 (43%), Gaps = 48/829 (5%)
 Frame = -3

Query: 3224 QHQKILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDR-EAHIK 3048
            +++K+ E+   LQ    +LQ + +  + +S  +    L+N  Y +L E    D+ +  I+
Sbjct: 1234 ENEKLQEEIDQLQNTIEKLQQENN--KSKSLLNTPNKLQNE-YETLQEEN--DKLQDEIE 1288

Query: 3047 QLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNA 2868
            +L   +  L +E  EL+N+        + L++E   LK+ +   +EE +   ELQ   + 
Sbjct: 1289 ELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIE---ELQNTIDK 1345

Query: 2867 LRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTE 2688
            L+  N+      + NN+L ++ +N+  E+    +      + LQN+ +S++Q +   Q E
Sbjct: 1346 LQNSNKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSPNKLQNENESLKQENEKLQEE 1405

Query: 2687 REELNRQLVLLRDDVNHLKEALSMAVDDRAFM----------EKQLQDLENQKETVSKEL 2538
             EEL   +  L+ + + LK   S++   +             EK  +++E  + T+ K L
Sbjct: 1406 IEELQNTVEKLQQENDLLKNNKSVSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDK-L 1464

Query: 2537 ALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLK 2358
              S    +KL  + K++       +N+     E+N++L+ EIE+L  +++  Q EN LLK
Sbjct: 1465 QNSNKSPKKLQQENKSMLNSPNKLQNEYETLQEENEKLQDEIEELQSTVEKLQQENDLLK 1524

Query: 2357 DGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKE-VGRSATDMKKVNSDAG 2181
            +         K ++   + +Q +   + +++  +++E+ + +  + +   +  K+ S + 
Sbjct: 1525 NSKS------KSVSPSPKRLQQENNSLKQENEKLQEEINQLQNTIEKLQNNKSKLYSPSP 1578

Query: 2180 AKVSGILEMLL----PMKDDVFSLKEE-------------VLGNINSLRNDAQMVQVALE 2052
             K+    E L      +++ +  L++E             +    NSL+ + + +Q  ++
Sbjct: 1579 KKLQNENESLKQENEKLQEQIEKLQQENDSKPKYSPSPRKLQQENNSLKQENEKLQEEID 1638

Query: 2051 QMQDT---------KSELFAEAEIRAQ-EVLRLQAEVDAIQHILIELKRKNQTLQDESQ- 1905
            Q+Q+T         KS+       + Q E   LQ E D +Q  + EL+   + LQ E++ 
Sbjct: 1639 QLQNTIEKLQQENNKSKSLLNTPNKLQNEYETLQEENDKLQDKIEELQSTIEKLQQENEE 1698

Query: 1904 -RNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEER---NVVESEHN 1737
             +N K +++   +   + ++N +L+ +N  L+ E+        ++Q E    N ++ E+N
Sbjct: 1699 LKNNKPIYSPSPK--KLQNENNSLKQENEKLQEEIEELQNTIDKLQIENKSPNKLQQENN 1756

Query: 1736 VLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELI 1557
             L  E+ENLK E++++   + Y  +  +            +  S +   EKL   +DE  
Sbjct: 1757 SLKQEIENLKEEIEQNNKSKSYSPKKLQ-----------QENNSLKQENEKLQEEIDE-- 1803

Query: 1556 CLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSG 1377
             L+N   KL+NE   +    E   +     E  S +        + N+    NK   S  
Sbjct: 1804 -LQNTVDKLQNENNLQSLQEENDKLQDEIEELQSTVEKLQ----QENEELKNNKPIYSPS 1858

Query: 1376 VDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXX 1197
               L+N+   L+ + +KL E                 ++EE+Q T+  +           
Sbjct: 1859 PKKLQNENNSLKQENEKLQE-----------------EIEELQNTIDKLQIENKSPNKLQ 1901

Query: 1196 IRVRSLKKENTRLRSEMKGELTPSRSFK----HREGSFIKEINIGDEDDTPLIQXXXXXX 1029
                SLK+E   L+ E++ +   S+S+      +E + +K+ N   +++   +Q      
Sbjct: 1902 QENNSLKQEIENLKEEIE-QNNKSKSYSPKKLQQENNSLKQENEKLQEEIDELQ------ 1954

Query: 1028 XXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQ 882
                  +D   +E   + +L ++N K  + +       + LQ   +EL+
Sbjct: 1955 ----NTVDKLQNE-NNLQSLQEENDKLQDEIEELQSTVEKLQQENEELK 1998



 Score =  137 bits (344), Expect = 4e-29
 Identities = 173/890 (19%), Positives = 388/890 (43%), Gaps = 109/890 (12%)
 Frame = -3

Query: 3224 QHQKILEDYYALQKKAGELQTKVHIRE-EESCKHLTEALENHIYGSLLESCVVDREAHIK 3048
            +++K+ E+   LQ    +LQ + +++  +E    L + +E       L+S V   +   +
Sbjct: 834  ENEKLQEEIEELQNTVDKLQNENNLQSLQEENDKLQDEIEE------LQSTVEKLQQENE 887

Query: 3047 QLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNA 2868
            +L           ++L+N+    ++ ++ L++++ +L+      +   +   +LQ+  N+
Sbjct: 888  ELKNNKPIYSPSPKKLQNENNSLKQENEKLQEQIEELQNTIDKLQNSNKSPNKLQQENNS 947

Query: 2867 LRQKNEDICLKIEANN-------NLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQM 2709
            L+Q+ E++  +IE NN       N L+ ++  + + + KLQE  E+   LQN ++ ++Q 
Sbjct: 948  LKQEIENLKEEIEQNNKSKSYSPNKLQNENESLKQENEKLQEQIEE---LQNTVEKLQQE 1004

Query: 2708 HAVSQTER------EELNRQLVLLRDDVNHLKEALSMAVDDRAFM---EKQLQDLENQKE 2556
            + + +  +      ++L ++  LL+++ +       +  ++ +     EK  +++E  + 
Sbjct: 1005 NDLLKNNKSVSPSPKKLQQENDLLKNNKSVSPSPKKLQNENNSLKQENEKLQEEIEELQN 1064

Query: 2555 TVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQM 2376
            T+ K L  S    +KL  + K++       +N+     E+N++L+ EIE+L  +++  Q 
Sbjct: 1065 TIDK-LQNSNKSPKKLQQENKSMLNSPNKLQNEYETLQEENEKLQDEIEELQSTVEKLQQ 1123

Query: 2375 ENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKE-VGRSATDMKK 2199
            EN LLK+         K ++   + +Q +   + +++  +++E+ + +  + +   +  K
Sbjct: 1124 ENDLLKNSKS------KSVSPSPKRLQQENNSLKQENEKLQEEINQLQNTIEKLQNNKSK 1177

Query: 2198 VNSDAGAKVSGILEMLL----PMKDDVFSLKEE-------------VLGNINSLRNDAQM 2070
            + S +  K+    E L      +++ +  L++E             +    NSL+ + + 
Sbjct: 1178 LYSPSPKKLQNENESLKQENEKLQEQIEKLQQENDSKPKYSPSPRKLQQENNSLKQENEK 1237

Query: 2069 VQVALEQMQDT---------KSELFAEAEIRAQ-EVLRLQAEVDAIQHILIELKRKNQTL 1920
            +Q  ++Q+Q+T         KS+       + Q E   LQ E D +Q  + EL+   + L
Sbjct: 1238 LQEEIDQLQNTIEKLQQENNKSKSLLNTPNKLQNEYETLQEENDKLQDEIEELQSTVEKL 1297

Query: 1919 QDESQ--RNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEER---NV 1755
            Q E++  +N K +++   +   + ++N +L+ +N  L+ E+        ++Q      N 
Sbjct: 1298 QQENEELKNNKPIYSPSPK--KLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSPNK 1355

Query: 1754 VESEHNVLSSEVENLKSELKESKDLEGYF---LRLFEILLGQHVEVASLDIESCRFAEEK 1584
            ++ E+N L  E+ENLK E++++   + Y    L+     L Q  E    +IE  +   EK
Sbjct: 1356 LQQENNSLKQEIENLKEEIEQNNKSKSYSPNKLQNENESLKQENEKLQEEIEELQNTVEK 1415

Query: 1583 LM-----------------RILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMS 1455
            L                  ++ +E   L+ EN KL+ E     +  ++   S    + + 
Sbjct: 1416 LQQENDLLKNNKSVSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSPKKLQ 1475

Query: 1454 VLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMF--------- 1302
                  L +    Q E++  +E++   + L+++   L+  V+KL ++ ++          
Sbjct: 1476 QENKSMLNSPNKLQNEYETLQEEN---EKLQDEIEELQSTVEKLQQENDLLKNSKSKSVS 1532

Query: 1301 -----------------ETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKK 1173
                             E    E  Q+ N +E++Q   S +               SLK+
Sbjct: 1533 PSPKRLQQENNSLKQENEKLQEEINQLQNTIEKLQNNKSKLYSPSPKKLQNEN--ESLKQ 1590

Query: 1172 ENTRLRSEM---------KGELTPSRSFKHREGSFIKEIN--IGDEDD--TPLIQXXXXX 1032
            EN +L+ ++         K + +PS     +E + +K+ N  + +E D     I+     
Sbjct: 1591 ENEKLQEQIEKLQQENDSKPKYSPSPRKLQQENNSLKQENEKLQEEIDQLQNTIEKLQQE 1650

Query: 1031 XXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQ 882
                   ++T      E +TL ++N K  +++       + LQ   +EL+
Sbjct: 1651 NNKSKSLLNTPNKLQNEYETLQEENDKLQDKIEELQSTIEKLQQENEELK 1700



 Score =  129 bits (324), Expect = 8e-27
 Identities = 199/941 (21%), Positives = 398/941 (42%), Gaps = 80/941 (8%)
 Frame = -3

Query: 3191 LQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHI-KQLMEQMNALVK 3015
            LQ +  EL+T++ I  +   K  +  ++++      +S  VD E  + K+  E++NA++ 
Sbjct: 726  LQMRNDELKTEIEILHQTIDKLTSARIKDN------DSKTVDNEIDLLKKENERLNAMLD 779

Query: 3014 EK--RELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNALRQKNEDIC 2841
            +   + +    +  E  S SLK E  +L+E     ++      +LQ+  N+L+Q+NE + 
Sbjct: 780  DSSMQIIMLQQEIDENKSNSLKQENEKLQEQIEELQKHSPSPKKLQQENNSLKQENEKLQ 839

Query: 2840 LKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLV 2661
             +IE   N +++  N      + LQ  +E+   LQ++++ ++      Q E EEL     
Sbjct: 840  EEIEELQNTVDKLQN-----ENNLQSLQEENDKLQDEIEELQSTVEKLQQENEELKNNKP 894

Query: 2660 LLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSE 2481
            +       L+   +    +   +++Q+++L+N   T+ K L  S     KL  +  +L +
Sbjct: 895  IYSPSPKKLQNENNSLKQENEKLQEQIEELQN---TIDK-LQNSNKSPNKLQQENNSLKQ 950

Query: 2480 KEESTKNQL------------LIQTE------QNKQLELEIEKLYGSLQMKQMENTLLKD 2355
            + E+ K ++             +Q E      +N++L+ +IE+L  +++  Q EN LLK+
Sbjct: 951  EIENLKEEIEQNNKSKSYSPNKLQNENESLKQENEKLQEQIEELQNTVEKLQQENDLLKN 1010

Query: 2354 GNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAK 2175
                     K ++   +++Q Q+  +LK + ++     + +    S     +   +   +
Sbjct: 1011 N--------KSVSPSPKKLQ-QENDLLKNNKSVSPSPKKLQNENNSLKQENEKLQEEIEE 1061

Query: 2174 VSGILEMLLPMKDDVFSLKEE---VLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIR 2004
            +   ++ L         L++E   +L + N L+N+ + +Q   E++QD   EL +  E  
Sbjct: 1062 LQNTIDKLQNSNKSPKKLQQENKSMLNSPNKLQNEYETLQEENEKLQDEIEELQSTVEKL 1121

Query: 2003 AQE--VLR------LQAEVDAIQHILIELKRKNQTLQDE---SQRNAKELWNAKARLNNV 1857
             QE  +L+      +      +Q     LK++N+ LQ+E    Q   ++L N K++L + 
Sbjct: 1122 QQENDLLKNSKSKSVSPSPKRLQQENNSLKQENEKLQEEINQLQNTIEKLQNNKSKLYSP 1181

Query: 1856 MSKNINLESQNRSLKAE---LHLQAQKAFQ--------------IQEERNVVESEHNVLS 1728
              K   L+++N SLK E   L  Q +K  Q              +Q+E N ++ E+  L 
Sbjct: 1182 SPK--KLQNENESLKQENEKLQEQIEKLQQENDSKPKYSPSPRKLQQENNSLKQENEKLQ 1239

Query: 1727 SE-------VENLKSELKESKDLEGYFLRL---FEILLGQHVEVASLDIESCRFAEEKLM 1578
             E       +E L+ E  +SK L     +L   +E L  ++ ++   +IE  +   EKL 
Sbjct: 1240 EEIDQLQNTIEKLQQENNKSKSLLNTPNKLQNEYETLQEENDKLQD-EIEELQSTVEKLQ 1298

Query: 1577 RILDEL-----------ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLG 1431
            +  +EL             L+NEN  LK E      + E    +  + +  +   +K   
Sbjct: 1299 QENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSPNKLQQ 1358

Query: 1430 NGRANQREFQN-KEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEE 1254
               + ++E +N KEE             +L+ + + L ++ E  + +  E Q    KL++
Sbjct: 1359 ENNSLKQEIENLKEEIEQNNKSKSYSPNKLQNENESLKQENEKLQEEIEELQNTVEKLQQ 1418

Query: 1253 MQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIG 1074
                L +                SLK+EN +L+ E++ EL           + I ++   
Sbjct: 1419 ENDLLKNNKSVSPSPKKLQNENNSLKQENEKLQEEIE-ELQ----------NTIDKLQNS 1467

Query: 1073 DEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSV 894
            ++    L Q            +++      E +TL ++N K  + +       + LQ++V
Sbjct: 1468 NKSPKKLQQ-------ENKSMLNSPNKLQNEYETLQEENEKLQDEI-------EELQSTV 1513

Query: 893  QELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAW 714
            ++LQQ                      S+    K L      L + N +L++++      
Sbjct: 1514 EKLQQENDLLK-----------NSKSKSVSPSPKRLQQENNSLKQENEKLQEEIN---QL 1559

Query: 713  ANSMHDLNGQEQKL------KVDEEVPILCHQNSKIAERLD 609
             N++  L   + KL      K+  E   L  +N K+ E+++
Sbjct: 1560 QNTIEKLQNNKSKLYSPSPKKLQNENESLKQENEKLQEQIE 1600



 Score =  124 bits (310), Expect = 3e-25
 Identities = 139/657 (21%), Positives = 300/657 (45%), Gaps = 21/657 (3%)
 Frame = -3

Query: 3050 KQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKE-VSRLYEEE------KQHTI 2892
            K+L ++  +++    +L+N+ +  +E ++ L+DE+ +L+  V +L +E       K  ++
Sbjct: 1472 KKLQQENKSMLNSPNKLQNEYETLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKSKSV 1531

Query: 2891 E-----LQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDM 2727
                  LQ+  N+L+Q+NE +  +I    N +E+  N      +K +        LQN+ 
Sbjct: 1532 SPSPKRLQQENNSLKQENEKLQEEINQLQNTIEKLQN------NKSKLYSPSPKKLQNEN 1585

Query: 2726 QSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVS 2547
            +S++Q       E E+L  Q+  L+ + N  K   S +      ++++   L+ + E + 
Sbjct: 1586 ESLKQ-------ENEKLQEQIEKLQQE-NDSKPKYSPSPRK---LQQENNSLKQENEKLQ 1634

Query: 2546 KE---LALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQM 2376
            +E   L  ++ + Q+  +  K+L       +N+     E+N +L+ +IE+L  +++  Q 
Sbjct: 1635 EEIDQLQNTIEKLQQENNKSKSLLNTPNKLQNEYETLQEENDKLQDKIEELQSTIEKLQQ 1694

Query: 2375 ENTLLKDGNEKIYDLC-KLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKK 2199
            EN  LK+ N+ IY    K L  ++  ++ + E + ++   +++ + + +   +S   +++
Sbjct: 1695 ENEELKN-NKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQIENKSPNKLQQ 1753

Query: 2198 VNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFA 2019
             N+    ++  + E +           +++    NSL+ + + +Q  ++++Q+T  +L  
Sbjct: 1754 ENNSLKQEIENLKEEIEQNNKSKSYSPKKLQQENNSLKQENEKLQEEIDELQNTVDKLQN 1813

Query: 2018 EAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQ--RNAKELWNAKARLNNVMSKN 1845
            E  +++     LQ E D +Q  + EL+   + LQ E++  +N K +++   +   + ++N
Sbjct: 1814 ENNLQS-----LQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPK--KLQNEN 1866

Query: 1844 INLESQNRSLKAELHLQAQKAFQIQEER---NVVESEHNVLSSEVENLKSELKESKDLEG 1674
             +L+ +N  L+ E+        ++Q E    N ++ E+N L  E+ENLK E++++   + 
Sbjct: 1867 NSLKQENEKLQEEIEELQNTIDKLQIENKSPNKLQQENNSLKQEIENLKEEIEQNNKSKS 1926

Query: 1673 YFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYE 1494
            Y  +  +            +  S +   EKL   +DEL   +N   KL+NE   +    E
Sbjct: 1927 YSPKKLQ-----------QENNSLKQENEKLQEEIDEL---QNTVDKLQNENNLQSLQEE 1972

Query: 1493 RKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEK 1314
               +     E  S +        + N+    NK   S     L+N+   L+ + +KL E+
Sbjct: 1973 NDKLQDEIEELQSTVEKLQ----QENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEE 2028

Query: 1313 AEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK 1143
                             +EE+Q T+  +               SLK+E   L+ E++
Sbjct: 2029 -----------------IEELQNTIDKLQIENKSPNKLQQENNSLKQEIENLKEEIE 2068



 Score =  115 bits (289), Expect = 9e-23
 Identities = 117/551 (21%), Positives = 252/551 (45%), Gaps = 33/551 (5%)
 Frame = -3

Query: 3224 QHQKILEDYYALQKKAGELQT----------KVHIREEESCKHLTEALENHIYGSLLESC 3075
            +++K+ E+   LQ    +LQ           K    E ES K   E L+  I     E+ 
Sbjct: 1548 ENEKLQEEINQLQNTIEKLQNNKSKLYSPSPKKLQNENESLKQENEKLQEQIEKLQQEND 1607

Query: 3074 VVDREAHIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHT 2895
               + +   + ++Q N  +K++ E     +  EEI Q L++ + +L++ +   +      
Sbjct: 1608 SKPKYSPSPRKLQQENNSLKQENE-----KLQEEIDQ-LQNTIEKLQQENNKSKSLLNTP 1661

Query: 2894 IELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVE 2715
             +LQ  +  L+++N+ +  KIE   + +E+      EL +           LQN+  S++
Sbjct: 1662 NKLQNEYETLQEENDKLQDKIEELQSTIEKLQQENEELKNNKPIYSPSPKKLQNENNSLK 1721

Query: 2714 QMHAVSQTEREELNRQLVLL-----------------RDDVNHLKEALSMAVDDRAFMEK 2586
            Q +   Q E EEL   +  L                 + ++ +LKE +      +++  K
Sbjct: 1722 QENEKLQEEIEELQNTIDKLQIENKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSPK 1781

Query: 2585 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEK 2406
            +LQ   N  +  +++L   +   Q     L+         +N L    E+N +L+ EIE+
Sbjct: 1782 KLQQENNSLKQENEKLQEEIDELQNTVDKLQ--------NENNLQSLQEENDKLQDEIEE 1833

Query: 2405 LYGSLQMKQMENTLLKDGNEKIYDLC-KLLATKSREVQGQQEGILKQDINIEDELARTKE 2229
            L  +++  Q EN  LK+ N+ IY    K L  ++  ++ + E + ++   +++ + + + 
Sbjct: 1834 LQSTVEKLQQENEELKN-NKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQI 1892

Query: 2228 VGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQ 2049
              +S   +++ N+    ++  + E +           +++    NSL+ + + +Q  +++
Sbjct: 1893 ENKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSPKKLQQENNSLKQENEKLQEEIDE 1952

Query: 2048 MQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQ--RNAKELWNAK 1875
            +Q+T  +L  E  +++     LQ E D +Q  + EL+   + LQ E++  +N K +++  
Sbjct: 1953 LQNTVDKLQNENNLQS-----LQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPS 2007

Query: 1874 ARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEER---NVVESEHNVLSSEVENLKS 1704
             +   + ++N +L+ +N  L+ E+        ++Q E    N ++ E+N L  E+ENLK 
Sbjct: 2008 PK--KLQNENNSLKQENEKLQEEIEELQNTIDKLQIENKSPNKLQQENNSLKQEIENLKE 2065

Query: 1703 ELKESKDLEGY 1671
            E++++   + Y
Sbjct: 2066 EIEQNNKSKSY 2076



 Score = 96.7 bits (239), Expect = 6e-17
 Identities = 167/943 (17%), Positives = 373/943 (39%), Gaps = 89/943 (9%)
 Frame = -3

Query: 3218 QKILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREA------ 3057
            Q + E+ ++L+ K   LQ ++   +E+  + +T  +E   Y         D+ +      
Sbjct: 42   QDLQEENFSLKMKINALQQQLATVQEQY-RTVTTRIEETTYQYQSNDSSQDQNSTDPKTK 100

Query: 3056 --------HIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEV--------FQLKEVS 2925
                     + + ME++    KE  +L+ + +  +E++ +L++++        FQ++++ 
Sbjct: 101  GGSSSDFGSVAEWMEKLERATKENDDLKREKETYQELAVTLQNQLDTQVSNFEFQIEKLQ 160

Query: 2924 RLYEEEKQHTIELQENFNALRQKNEDICLKIEANN--------NLLEQKDNII--VELSH 2775
            R  ++  +  ++LQE    L     D+  K +  N         L+++++  +  +E SH
Sbjct: 161  REKDDLSRLNVQLQEKIKLLSTSYTDLSAKFDKQNEDHEIEIAKLIDRQNERLKEIEESH 220

Query: 2774 K--LQENEEQRSALQNDMQ---------------SVEQMHAVSQTEREELNRQLVLLRDD 2646
            K  +Q+ +  +  L N +Q                 +Q+  + +  +EE  + + LL   
Sbjct: 221  KSNIQQIQTNKDGLTNQIQQEFTKTKEDLDKSRKEYKQLEELQRKAQEENTKTISLLNIQ 280

Query: 2645 VNHLKEALSMAVD----DRAFMEKQLQDLEN---QKETVSKELALSVSREQKLASDLKAL 2487
            +N L+  L  A      D   ++K + DLE    +K+ V + L+  V R ++  S+L+A 
Sbjct: 281  INQLQNQLEKAYSGKQADDVAVKKNIADLERSNAEKDVVIQSLSTKVGRFEEKVSNLEAK 340

Query: 2486 SEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKS 2307
              + E T  QL       + L+ +I      + +++ E  +  + N  + +       ++
Sbjct: 341  ISEYEKTIKQL---NNSKEDLQKQINNFSNKIDIERAEKQIYIENNNDLKE-----QIQN 392

Query: 2306 REVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVF 2127
             E++ Q+E   +++   E E  R K V  S    K                         
Sbjct: 393  DEIKFQKE---RKEFQQELENLRIKFVQLSNNTEKD------------------------ 425

Query: 2126 SLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILI 1947
            +L + +   IN+LR         +E  + T  +   E+ I     LR Q  +  +++  I
Sbjct: 426  NLIQHLQEEINALRQKLSEYSKIVENSKSTPGKESYESTITN---LRTQINMLKLENQEI 482

Query: 1946 ELKRKN-QTLQDESQRNAKELWNAKARLNNVMSKNINLES------QNRSLK---AELHL 1797
            +   +N  T++ +++   K++ + +++L         LE+      +N  LK    ++  
Sbjct: 483  KKDIENYDTMEKQNEEMKKQMDDLRSQLKENKDYQSQLENMKLIQEENDDLKERIGDMSN 542

Query: 1796 QAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILL-GQHVEVAS 1620
             + +  +++++ N  E+E  +L  +++NL  +  E +D+  +   + ++ +  Q ++   
Sbjct: 543  LSDQILELKKKLNDSENEKEILRKQIDNLCKD-DEEEDVPTFSKVISDLKVENQILKKKI 601

Query: 1619 LDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISK 1440
             D E      E L + ++E I + NEN +LK+E     ++ ++        E  +  + K
Sbjct: 602  SDSEQISKENEDLKKQINEYIDIENENDELKDEISTLQNNIQKITERNEEIEKQNDDLKK 661

Query: 1439 SLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSRE-----AQQ 1275
               N      +  N E+    +  L N+ T  + + + + E+ ++ + KS        + 
Sbjct: 662  ---NNDDLHVKIHNLEQKVDNLTNLNNELTINQMKYEDIKEENDLLKNKSASPVSATPRT 718

Query: 1274 MANKLEEMQQTLSDMXXXXXXXXXXXIRVRS-----------------LKKENTRLRSEM 1146
              NK++++Q    ++            ++ S                 LKKEN RL + +
Sbjct: 719  QQNKIQQLQMRNDELKTEIEILHQTIDKLTSARIKDNDSKTVDNEIDLLKKENERLNAML 778

Query: 1145 KGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLM 966
                         + S ++ I +  E D                +I+     +     L 
Sbjct: 779  -------------DDSSMQIIMLQQEIDENKSNSLKQENEKLQEQIEELQKHSPSPKKLQ 825

Query: 965  DDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKEL 786
             +N           ++ + LQN+V +LQ                    + + ++ +++EL
Sbjct: 826  QENNSLKQENEKLQEEIEELQNTVDKLQNENNLQSLQE----------ENDKLQDEIEEL 875

Query: 785  NIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEE 657
               V +L + N  LK +      ++ S   L  +   LK + E
Sbjct: 876  QSTVEKLQQENEELKNNKPI---YSPSPKKLQNENNSLKQENE 915



 Score = 91.3 bits (225), Expect = 3e-15
 Identities = 170/885 (19%), Positives = 366/885 (41%), Gaps = 66/885 (7%)
 Frame = -3

Query: 3191 LQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNALVKE 3012
            LQ++  +L ++++++ +E  K L+ +  +    +  +    D E  I +L+++ N  +KE
Sbjct: 159  LQREKDDL-SRLNVQLQEKIKLLSTSYTD--LSAKFDKQNEDHEIEIAKLIDRQNERLKE 215

Query: 3011 KRE---------------LENDAQRG-----EEISQSLKDEVFQLKEVSRLYEEEKQHTI 2892
              E               L N  Q+      E++ +S K E  QL+E+ R  +EE   TI
Sbjct: 216  IEESHKSNIQQIQTNKDGLTNQIQQEFTKTKEDLDKSRK-EYKQLEELQRKAQEENTKTI 274

Query: 2891 ELQE-NFNALRQKNE---------DICLK-----IEANNNLLEQKDNIIVELSHKLQENE 2757
             L     N L+ + E         D+ +K     +E +N    +KD +I  LS K+   E
Sbjct: 275  SLLNIQINQLQNQLEKAYSGKQADDVAVKKNIADLERSN---AEKDVVIQSLSTKVGRFE 331

Query: 2756 EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQ 2577
            E+ S L+  +   E+        +E+L +Q+    + ++  +    + +++   +++Q+Q
Sbjct: 332  EKVSNLEAKISEYEKTIKQLNNSKEDLQKQINNFSNKIDIERAEKQIYIENNNDLKEQIQ 391

Query: 2576 --DLENQKETVS----------KELALSVSRE-----QKLASDLKALSEK--EESTKNQL 2454
              +++ QKE             K + LS + E     Q L  ++ AL +K  E S   + 
Sbjct: 392  NDEIKFQKERKEFQQELENLRIKFVQLSNNTEKDNLIQHLQEEINALRQKLSEYSKIVEN 451

Query: 2453 LIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGIL 2274
               T   +  E  I  L   + M ++EN  +K   E  YD  +    + ++        L
Sbjct: 452  SKSTPGKESYESTITNLRTQINMLKLENQEIKKDIEN-YDTMEKQNEEMKKQMDDLRSQL 510

Query: 2273 KQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNIN 2094
            K++ + + +L   K +     D+K+   D       ILE+   + D   + KE +   I+
Sbjct: 511  KENKDYQSQLENMKLIQEENDDLKERIGDMSNLSDQILELKKKLNDSE-NEKEILRKQID 569

Query: 2093 SLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQ---T 1923
            +L  D +      E+   T S++ ++ ++  Q + +  ++ + I     +LK++      
Sbjct: 570  NLCKDDE------EEDVPTFSKVISDLKVENQILKKKISDSEQISKENEDLKKQINEYID 623

Query: 1922 LQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKA---ELHLQAQKAFQIQEERNVV 1752
            +++E+     E+   +  +  +  +N  +E QN  LK    +LH++     Q  +    +
Sbjct: 624  IENENDELKDEISTLQNNIQKITERNEEIEKQNDDLKKNNDDLHVKIHNLEQKVDNLTNL 683

Query: 1751 ESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRI 1572
             +E  +   + E++K E    K+     +          ++   +  +  +   E L + 
Sbjct: 684  NNELTINQMKYEDIKEENDLLKNKSASPVSATPRTQQNKIQQLQMRNDELKTEIEILHQT 743

Query: 1571 LDELICLR---NENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQ 1401
            +D+L   R   N++  + NE      + ER N     +    +++ + +   ++N  + +
Sbjct: 744  IDKLTSARIKDNDSKTVDNEIDLLKKENERLNAMLDDSSMQIIMLQQEIDENKSNSLKQE 803

Query: 1400 NKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXX 1221
            N++      +L K+  +  + Q +  S K        +E +++  ++EE+Q T+  +   
Sbjct: 804  NEKLQEQIEELQKHSPSPKKLQQENNSLK--------QENEKLQEEIEELQNTVDKL--- 852

Query: 1220 XXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXX 1041
                      ++SL++EN +L+ E++ EL  +     +E   +K            +Q  
Sbjct: 853  -----QNENNLQSLQEENDKLQDEIE-ELQSTVEKLQQENEELKNNKPIYSPSPKKLQNE 906

Query: 1040 XXXXXXXXXKIDTRTSETQE-IDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXX 864
                     K+  +  E Q  ID L + N+             Q ++N  +E++Q     
Sbjct: 907  NNSLKQENEKLQEQIEELQNTIDKLQNSNKSPNKLQQENNSLKQEIENLKEEIEQNNKSK 966

Query: 863  XXXXXXXXXKWGGI--DMNSIEKQLKELNIHVMQLVEHNTRLKKD 735
                     +   +  +   +++Q++EL   V +L + N  LK +
Sbjct: 967  SYSPNKLQNENESLKQENEKLQEQIEELQNTVEKLQQENDLLKNN 1011


>ref|XP_001581403.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
            gi|121915630|gb|EAY20417.1| viral A-type inclusion
            protein, putative [Trichomonas vaginalis G3]
          Length = 4263

 Score =  134 bits (337), Expect = 3e-28
 Identities = 174/899 (19%), Positives = 392/899 (43%), Gaps = 36/899 (4%)
 Frame = -3

Query: 3161 KVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQL---MEQMNALVKEK----RE 3003
            K     +ES K L   +E H      +  +  R+A I+QL   ++Q +  + EK    ++
Sbjct: 1592 KTIAERDESIKQLQNEIEQH------KQTISQRDAEIEQLKQTVQQRDQTIAEKEDLIKQ 1645

Query: 3002 LENDAQRGEEISQSLKDEVFQLKE--------VSRLYEEEKQHTIELQENFNALRQKNED 2847
            L+++ ++ ++      +E+ QLK+        + +L  E +QH   + E  +A  QKN++
Sbjct: 1646 LQSEIEQHKQTISDKNNEIEQLKQTVNARDEAIKQLQSEIEQHKQTIAER-DAEIQKNKE 1704

Query: 2846 ICLKIEANNNLLEQKDNIIVELSHKLQENEE---QRSALQNDMQSVEQMHAVSQTEREEL 2676
               +IE     + Q+D  I +L ++++++++   QR A    ++   Q    +  E+E+L
Sbjct: 1705 ---EIEQQKQTISQRDETIKQLQNEIEQHKQTISQRDAEIEQLKQTVQQSDQTIAEKEDL 1761

Query: 2675 NRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDL 2496
             +QL   + ++   K+ ++   +  A ++K  +++E QK+T+S+        + ++  + 
Sbjct: 1762 IKQL---QSEIEQHKQTIA---ERDAEIQKNKEEIEQQKQTISQRDESIKQMQSEIEQNK 1815

Query: 2495 KALSEKE---ESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCK 2325
            + ++++E   E  K  +  +    KQL+ EIE+   ++  +  E   ++   E+I    +
Sbjct: 1816 QTIADREKEIEQHKQTIAERDNSIKQLQEEIEQHKQTIAERDAE---IQKNKEEIQQKNE 1872

Query: 2324 LLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLP 2145
             +   + E + ++  IL+ + N E+ + + KE+  S +D+     +  + V  + + +  
Sbjct: 1873 AINALTNEGEEKRLKILELEANNENLINKVKELNDSVSDLNLSTENQNSVVKQMTDEIKD 1932

Query: 2144 MKDDVFSLK----------EEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQE 1995
            +   +  L+          EE    I SL N     +  ++++Q+    L        + 
Sbjct: 1933 LNKQIHELEVKSENQQKQIEEKDKEIQSLTNTKAQNEELIKKLQEEVENLTNTKNQNEET 1992

Query: 1994 VLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSL 1815
            +  LQ +V +    L E K +N+ L  + Q   + L N K      +    NL+ Q +SL
Sbjct: 1993 IKNLQEQVQS----LTETKNQNEDLIKKQQEQIQSLTNTKNENEETIK---NLQEQVQSL 2045

Query: 1814 KAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQH 1635
                  +A     I++ +  V+S     ++  E +K + +E + L        E++    
Sbjct: 2046 ---TETKATNEETIKKLQGEVQSLTETKATNEEQIKKQQEEIQSLSNTKNENEELIKKLQ 2102

Query: 1634 VEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMS 1455
             E+ +L     +  EE++ ++ +E+  L+ +NA+ K++ + E+ + +   +S S  E  +
Sbjct: 2103 EEIQNLTNTKTQ-NEEQIKKLQEEIQNLQKQNAE-KDDKINEF-NAKLSTLSSSSDELTT 2159

Query: 1454 VLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKL-SEKAEMFETKSREAQ 1278
              I+        NQ   QN E+D+  +  L  K + LE    +L +EK+++ + K+   Q
Sbjct: 2160 KFIN---AQNEINQLTKQNNEKDNL-ISQLNQKISDLENAKSQLENEKSQLIQEKTNLEQ 2215

Query: 1277 QMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGS 1098
            + A  LE+ +    +                 L +E T L  E    +    + +  +  
Sbjct: 2216 EKAQLLEQKKNLEEEKQKLETEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAK 2275

Query: 1097 FIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQ 918
             I+E    +++   LI+            I+ +T+  QE    +++        +   ++
Sbjct: 2276 LIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKPIEEKTNLEQEKAKLIEE 2335

Query: 917  TQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIE--KQLKELNIHVMQLVEHNTRL 744
              +L+    +L +              +   ++    +  ++   L     +L+E  T L
Sbjct: 2336 KTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNL 2395

Query: 743  KKDVKFGFAWANSMHD-LNGQEQKLKVDEEVPILCHQNSK-IAERLDINTDKARALDME 573
            +++       A  + +  N +++K K+ EE   L  + +K I E+ ++  +K++ LD +
Sbjct: 2396 EQEK------AKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKSQLLDQK 2448



 Score =  112 bits (280), Expect = 1e-21
 Identities = 155/702 (22%), Positives = 302/702 (43%), Gaps = 54/702 (7%)
 Frame = -3

Query: 3188 QKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIK-------QLMEQM 3030
            ++K  E   +     + S K L E +E H      +  + +R+A I+       Q  E +
Sbjct: 1821 REKEIEQHKQTIAERDNSIKQLQEEIEQH------KQTIAERDAEIQKNKEEIQQKNEAI 1874

Query: 3029 NALVKEKRELENDAQRGEEISQSLKDEVFQLKE-VSRL-YEEEKQHTI--ELQENFNALR 2862
            NAL  E  E        E  +++L ++V +L + VS L    E Q+++  ++ +    L 
Sbjct: 1875 NALTNEGEEKRLKILELEANNENLINKVKELNDSVSDLNLSTENQNSVVKQMTDEIKDLN 1934

Query: 2861 QKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTERE 2682
            ++  ++ +K E     +E+KD  I  L++   +NEE    LQ +++++      ++   +
Sbjct: 1935 KQIHELEVKSENQQKQIEEKDKEIQSLTNTKAQNEELIKKLQEEVENLTNTKNQNEETIK 1994

Query: 2681 ELNRQLVLLRDDVNH-------LKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVS 2523
             L  Q+  L +  N         +E +    + +   E+ +++L+ Q +++++  A +  
Sbjct: 1995 NLQEQVQSLTETKNQNEDLIKKQQEQIQSLTNTKNENEETIKNLQEQVQSLTETKATNEE 2054

Query: 2522 REQKLASDLKALSEKEESTKNQLLIQTEQNKQL---ELEIEKLYGSLQMKQMENTLLKDG 2352
              +KL  ++++L+E + + + Q+  Q E+ + L   + E E+L   LQ +    T  K  
Sbjct: 2055 TIKKLQGEVQSLTETKATNEEQIKKQQEEIQSLSNTKNENEELIKKLQEEIQNLTNTKTQ 2114

Query: 2351 NEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMK---------- 2202
            NE+   + KL      E+Q  Q+   ++D  I +  A+   +  S+ ++           
Sbjct: 2115 NEE--QIKKL----QEEIQNLQKQNAEKDDKINEFNAKLSTLSSSSDELTTKFINAQNEI 2168

Query: 2201 ----KVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQ---MQ 2043
                K N++    +S + + +  +++    L+ E    I    N  Q     LEQ   ++
Sbjct: 2169 NQLTKQNNEKDNLISQLNQKISDLENAKSQLENEKSQLIQEKTNLEQEKAQLLEQKKNLE 2228

Query: 2042 DTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLN 1863
            + K +L  E     QE  +L  E   ++    +L  +   L+ E  +  +E  N +    
Sbjct: 2229 EEKQKLETEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKA 2288

Query: 1862 NVMSKNINLESQNRSLKAE-LHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSE----L 1698
             ++ +  NLE +   L  E  +L+ +KA  I+E+ N+ E E   L  E  NL+ E    +
Sbjct: 2289 KLIEEKTNLEQEKAKLIEEKTNLEQEKAKPIEEKTNL-EQEKAKLIEEKTNLEQEKAKLI 2347

Query: 1697 KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEA 1518
            +E  +LE    +L E       E A L  E     +EK  ++++E   L  E AKL  E 
Sbjct: 2348 EEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKA-KLIEEKTNLEQEKAKLIEE- 2405

Query: 1517 LYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKN---KCTR 1347
                    + N+   +A+ +    +      +  + +   ++E S  +D  KN   +  R
Sbjct: 2406 --------KTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKSQLLDQKKNLEEEKQR 2457

Query: 1346 LEFQVQKL--------SEKAEMFETKSREAQQMANKLEEMQQ 1245
            LE +  KL         EKA++ E K    ++ A   EE  Q
Sbjct: 2458 LETEKAKLIEDKTNLEQEKAQLLEQKKNLEEEKAKLEEEKAQ 2499



 Score =  111 bits (278), Expect = 2e-21
 Identities = 145/701 (20%), Positives = 301/701 (42%), Gaps = 49/701 (6%)
 Frame = -3

Query: 3191 LQKKAGELQ--TKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNALV 3018
            +++K  E+Q  T    + EE  K L E +EN      L +     E  IK L EQ+ +L 
Sbjct: 1951 IEEKDKEIQSLTNTKAQNEELIKKLQEEVEN------LTNTKNQNEETIKNLQEQVQSLT 2004

Query: 3017 KEKRE--------------LENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQE 2880
            + K +              L N     EE  ++L+++V  L E     EE  +      +
Sbjct: 2005 ETKNQNEDLIKKQQEQIQSLTNTKNENEETIKNLQEQVQSLTETKATNEETIKKLQGEVQ 2064

Query: 2879 NFNALRQKNEDICLK----IEANNNLLEQKDNIIVELSHKLQ-------ENEEQRSALQN 2733
            +    +  NE+   K    I++ +N   + + +I +L  ++Q       +NEEQ   LQ 
Sbjct: 2065 SLTETKATNEEQIKKQQEEIQSLSNTKNENEELIKKLQEEIQNLTNTKTQNEEQIKKLQE 2124

Query: 2732 DMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKET 2553
            ++Q++++ +A    +  E N +L  L    + L      A ++   + KQ  + +N    
Sbjct: 2125 EIQNLQKQNAEKDDKINEFNAKLSTLSSSSDELTTKFINAQNEINQLTKQNNEKDNLISQ 2184

Query: 2552 VSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQME 2373
            ++++++   + + +L ++   L +++ + + +     EQ K LE E +KL       + E
Sbjct: 2185 LNQKISDLENAKSQLENEKSQLIQEKTNLEQEKAQLLEQKKNLEEEKQKL-------ETE 2237

Query: 2372 NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVN 2193
             T L+    K+ +       +   ++ ++  ++++  N+E E A+  E     T++++  
Sbjct: 2238 KTNLEQEKAKLIE-------EKTNLEQEKAKLIEEKTNLEQEKAKLIE---EKTNLEQEK 2287

Query: 2192 SDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQ---MQDTKSELF 2022
            +    + + + +    + ++  +L++E    I    N  Q     +E+   ++  K++L 
Sbjct: 2288 AKLIEEKTNLEQEKAKLIEEKTNLEQEKAKPIEEKTNLEQEKAKLIEEKTNLEQEKAKLI 2347

Query: 2021 AEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNI 1842
             E     QE  +L  E   ++    +L  +   L+ E  +  +E  N +     ++ +  
Sbjct: 2348 EEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKT 2407

Query: 1841 NLESQNRSLKAE-LHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSE-----------L 1698
            NLE +   L  E  +L+ +KA  I+E+ N+ E E + L  + +NL+ E           +
Sbjct: 2408 NLEQEKAKLIEEKTNLEQEKAKLIEEKTNL-EQEKSQLLDQKKNLEEEKQRLETEKAKLI 2466

Query: 1697 KESKDLEGYFLRLFEILLGQHVEVASLDIESC---RFAEEKLMRILDELICLRNENAKLK 1527
            ++  +LE    +L E       E A L+ E     +  EEK   I D        N K K
Sbjct: 2467 EDKTNLEQEKAQLLEQKKNLEEEKAKLEEEKAQAQKTIEEKDQEIED---LTSQINVKTK 2523

Query: 1526 NEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNK-EEDSSGVDLLKNKCT 1350
            + +L E  D+   + + +    M     K L +      + QN+ ++ +   D L++K  
Sbjct: 2524 DLSLLE-SDFNNMSFTNADQSTMISNYEKELSDKNKEINDLQNQLKQMTQNRDELQSKSD 2582

Query: 1349 RLEFQVQK---LSEKAEMFETKSREAQQMANKLEEMQQTLS 1236
            +L  ++++   +       E K++E + +  +L + Q  LS
Sbjct: 2583 KLNEEIEEKKNIQNLESSLEQKNKENEDLKQQLNKTQGELS 2623



 Score =  110 bits (276), Expect = 3e-21
 Identities = 153/723 (21%), Positives = 314/723 (43%), Gaps = 28/723 (3%)
 Frame = -3

Query: 3215 KILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLME 3036
            K++ED   L+++  +L  +    EEE  K   E  +        +  + +++  I+ L  
Sbjct: 2464 KLIEDKTNLEQEKAQLLEQKKNLEEEKAKLEEEKAQ-------AQKTIEEKDQEIEDLTS 2516

Query: 3035 QMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNALRQK 2856
            Q+N   K+   LE+D      +S +  D+   +    +   ++ +   +LQ     + Q 
Sbjct: 2517 QINVKTKDLSLLESDFNN---MSFTNADQSTMISNYEKELSDKNKEINDLQNQLKQMTQN 2573

Query: 2855 NEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREEL 2676
             +++  K +  N  +E+K NI    S   Q+N+E     Q   ++  ++ A  Q + +EL
Sbjct: 2574 RDELQSKSDKLNEEIEEKKNIQNLESSLEQKNKENEDLKQQLNKTQGELSAQLQQKTQEL 2633

Query: 2675 NRQLVLLRDDVNHLKEALSMAVDDRAFMEKQL--------QDLENQKETVSKELALSVSR 2520
                    D     ++ ++   ++ A ++K +        Q LEN+   + K+L+    +
Sbjct: 2634 ENLTKEFNDLKQKSEQTIAQNNEEIANLKKNVAERDKKISQLLENEVNELKKKLS---DK 2690

Query: 2519 EQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKI 2340
            E +  S    +SE+E    N  L +   +K  E EI +L  +L M++ E   +KD  E++
Sbjct: 2691 ENENTSLKNTISERENEINN--LKKNVSDK--ENEINQLKNNLTMRETELNKMKD--EEV 2744

Query: 2339 YDLCKLLATKSR---EVQGQQEGILKQDINIEDELARTKE----VGRSATDMKKVNSDAG 2181
             +  +++A K +   E+ G+            DEL + KE    + +    MK  N+   
Sbjct: 2745 KNAKQIIAQKDKDLEELNGKFNDTNNNLSKANDELKQLKEQIESLNKQIEQMKCSNNLKE 2804

Query: 2180 AKVSGILEMLLPMKDDVFSLKEEVL---GNINSLRNDAQMVQVALEQMQDTKSELFAEAE 2010
            +++  +   L   K  +  L ++       IN L N+ + +Q  L+Q Q+   E   + +
Sbjct: 2805 SEIKQLTSNLQKYKQALKELNDQNKQKDSQINQLNNEMKELQQTLKQTQEQLKETQDQLK 2864

Query: 2009 IRAQEVLRLQAE--VDAIQHILIELKRKNQTLQDESQRNAK----ELWNAK----ARLNN 1860
             + QE L  + +    + + +  ELK+K Q + D+ Q N K    EL + K    A+ N 
Sbjct: 2865 -QTQETLATKEKEFAKSAEDLNNELKKKQQAI-DDLQNNLKQKDAELTDTKQKLEAKTNE 2922

Query: 1859 VMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDL 1680
                    E++  SL+ E+     K     +E    +SE ++   E + LK  L +    
Sbjct: 2923 FNDLKQKAENEIASLRKEIEQLKAKLANTSKELEASKSESDLQKKENDKLKVNLAK---- 2978

Query: 1679 EGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHD 1500
                  +++ L  +    ++   +  +  +EK+  +      ++ E  KL NE L   + 
Sbjct: 2979 ---IAEMYKTLKSESENNSAKSNDKIKQMQEKIQNLE-----IQVEKMKLANENLTNENK 3030

Query: 1499 YERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLS 1320
             +++ +     E ++  + +S  +  A+ +E++  + ++   +L K++ T+L  QVQKL+
Sbjct: 3031 LQKETI-----EMLNKKLLESNKSLTASIKEYETLKREN---NLQKDQITKLTSQVQKLT 3082

Query: 1319 EKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKG 1140
            +    F    +E  ++ +KL E+   L+               +  LK EN +L +E+  
Sbjct: 3083 QD---FTQLKKEKAEVDSKLNELLDLLAQ----------KDKEIERLKSENQKL-NELYQ 3128

Query: 1139 ELT 1131
            ++T
Sbjct: 3129 QIT 3131



 Score =  109 bits (272), Expect = 9e-21
 Identities = 187/967 (19%), Positives = 403/967 (41%), Gaps = 81/967 (8%)
 Frame = -3

Query: 3224 QHQKILEDYYALQKKAGELQTKVHIREEESCKHLTEALE-----NHIYGSLLESCVVDRE 3060
            Q +++ ++   LQ K+ +L  +  I E+++ ++L  +LE     N      L     +  
Sbjct: 2566 QLKQMTQNRDELQSKSDKLNEE--IEEKKNIQNLESSLEQKNKENEDLKQQLNKTQGELS 2623

Query: 3059 AHIKQLMEQMNALVKEKRELEND-----AQRGEEISQSLKDEVFQLKEVSRLYEEEKQHT 2895
            A ++Q  +++  L KE  +L+       AQ  EEI+   K+   + K++S+L E E    
Sbjct: 2624 AQLQQKTQELENLTKEFNDLKQKSEQTIAQNNEEIANLKKNVAERDKKISQLLENEVN-- 2681

Query: 2894 IELQENFNALRQKNEDICLKIEAN----NNL---LEQKDNIIVELSHKLQENEEQRSALQ 2736
             EL++  +    +N  +   I       NNL   +  K+N I +L + L   E + + ++
Sbjct: 2682 -ELKKKLSDKENENTSLKNTISERENEINNLKKNVSDKENEINQLKNNLTMRETELNKMK 2740

Query: 2735 ND-MQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 2559
            ++ +++ +Q+ A    + EELN +     D  N+L +A             +L+ L+ Q 
Sbjct: 2741 DEEVKNAKQIIAQKDKDLEELNGK---FNDTNNNLSKA-----------NDELKQLKEQI 2786

Query: 2558 ETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQ 2379
            E+++K++           S++K L+   +  K  L    +QNKQ + +I +L  + +MK+
Sbjct: 2787 ESLNKQIEQMKCSNNLKESEIKQLTSNLQKYKQALKELNDQNKQKDSQINQL--NNEMKE 2844

Query: 2378 MENTL------LKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRS 2217
            ++ TL      LK+  +++    + LATK +E     E     D+N E      K+  ++
Sbjct: 2845 LQQTLKQTQEQLKETQDQLKQTQETLATKEKEFAKSAE-----DLNNE-----LKKKQQA 2894

Query: 2216 ATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDT 2037
              D++       A+++   + L    ++   LK++    I SLR + + ++  L      
Sbjct: 2895 IDDLQNNLKQKDAELTDTKQKLEAKTNEFNDLKQKAENEIASLRKEIEQLKAKLANTSKE 2954

Query: 2036 KSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQT----LQDESQRNAKELWNAKAR 1869
                 +E++++ +E  +L+  +  I  +   LK +++       D+ ++  +++ N + +
Sbjct: 2955 LEASKSESDLQKKENDKLKVNLAKIAEMYKTLKSESENNSAKSNDKIKQMQEKIQNLEIQ 3014

Query: 1868 LNNVMSKNINLESQNRSLKAELHLQAQKAFQ--------------IQEERNVVESEHNVL 1731
            +  +   N NL ++N+  K  + +  +K  +              ++ E N+ + +   L
Sbjct: 3015 VEKMKLANENLTNENKLQKETIEMLNKKLLESNKSLTASIKEYETLKRENNLQKDQITKL 3074

Query: 1730 SSEVENLKSEL----KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAE--EKLMRIL 1569
            +S+V+ L  +     KE  +++     L ++L  +  E+  L  E+ +  E  +++ + L
Sbjct: 3075 TSQVQKLTQDFTQLKKEKAEVDSKLNELLDLLAQKDKEIERLKSENQKLNELYQQITKDL 3134

Query: 1568 DEL-ICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKE 1392
            +E    ++++N    N  +   +  E+KN      +  +  ++ SL   +   RE     
Sbjct: 3135 EEKEFLIQSQN----NRCIDLLNLTEKKNKEIETLQISNDSLNNSLTKSQMELREKSTLL 3190

Query: 1391 EDSSG-----------VDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQ 1245
            E++              D L    + L         K       S +       + + +Q
Sbjct: 3191 ENAKDKITESNRKLALFDRLSANSSELNLTSSGRGIKKSSSMNLSTDMDSKNKIINQQEQ 3250

Query: 1244 TLSDMXXXXXXXXXXXIRV-RSLKKE---NTRLRSEMKGELTPSRSFKHREGSFIKEINI 1077
            T+  +               R L+K+   N  L++++K         + +  S +K++N 
Sbjct: 3251 TIIGLEQSLKVSKNEVDATKRELQKQLQNNKELQNQIKMTKEQFAKLEAKLQSVVKKLND 3310

Query: 1076 GDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDD----NRKYWNRVSHFTKQTQS 909
             D+    L+              D    +T +++  + D    N K   RV   T++ QS
Sbjct: 3311 KDQRIDSLMSS------------DPNNKQTNQLNKQISDLNLENEKLKTRVDIITRENQS 3358

Query: 908  LQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVK 729
            L++ ++   Q              K   I+  SI  Q KE    +M+ +    +   ++K
Sbjct: 3359 LKDDLE--SQKSQKSKLDESCNALKTELINKKSIMDQYKEKLKELMEQINLKNKQISELK 3416

Query: 728  FGFAWAN--------SMHDLNGQEQKLKV--DEEVPILCHQNSKIAE---RLDINTDKAR 588
              F  ++         + +  G+  +LKV  D +   +  Q  KIA+    L  + D+A+
Sbjct: 3417 AEFNGSDDEDRKSYVKVIEQEGEITELKVIIDRQKKFVGQQKMKIADLEKNLKESNDEAQ 3476

Query: 587  ALDMEVQ 567
             +   +Q
Sbjct: 3477 KMTKNLQ 3483



 Score =  106 bits (265), Expect = 6e-20
 Identities = 194/1004 (19%), Positives = 414/1004 (41%), Gaps = 100/1004 (9%)
 Frame = -3

Query: 3218 QKILEDYYALQKKAGELQTKVHIREEES-------CKHLTEALE--NHIYGS--LLESCV 3072
            Q+I E    L+KK  E   K+   +EE+        K L EA E  N + G+  + E  +
Sbjct: 1346 QRISELEMLLEKKDKENNDKIAEIQEENRQTLEQLAKQLQEAEEDINVLEGNCQVYEQEI 1405

Query: 3071 VDREAHIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKE-VSRLYEEEKQHT 2895
             +++  I+Q+   + +L +   E  N     ++   + ++E+ QLK+ VS   E  KQ  
Sbjct: 1406 AEKDKQIEQMTNDIKSLEEVINEQSNTIDSLKQDVATKEEEIKQLKQTVSENEEVIKQLQ 1465

Query: 2894 IELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVE 2715
             ++++  +A  QKN++   +IE +   + Q+D  I +L  +++++++  +   N+++ ++
Sbjct: 1466 TDIEQK-DAEIQKNKE---EIEQHKQTISQRDETIKQLQSEIEQHKQTIADKNNEIEQLK 1521

Query: 2714 QMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELA 2535
                 + +EREE  +QL       N +++      +  A ++K  +++E QK+T+S    
Sbjct: 1522 N----TISEREETIKQLQ------NEIEQHKQTMAERDAEIQKNKEEIEQQKQTIS---- 1567

Query: 2534 LSVSREQKLASDLKALSEKE---ESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTL 2364
               +   ++    K +SE++   E  K  +  + E  KQL+ EIE+   ++  +  E   
Sbjct: 1568 ---NNNNEIEQLKKTISERDAEIEQLKKTIAERDESIKQLQNEIEQHKQTISQRDAEIEQ 1624

Query: 2363 LK----DGNEKIYDLCKLLATKSREVQGQQEGI---------LKQDINIEDELARTKEVG 2223
            LK      ++ I +   L+     E++  ++ I         LKQ +N  DE    K++ 
Sbjct: 1625 LKQTVQQRDQTIAEKEDLIKQLQSEIEQHKQTISDKNNEIEQLKQTVNARDE--AIKQLQ 1682

Query: 2222 RSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVL------------------GNI 2097
                  K+  ++  A++    E +   K  + S ++E +                    I
Sbjct: 1683 SEIEQHKQTIAERDAEIQKNKEEIEQQKQTI-SQRDETIKQLQNEIEQHKQTISQRDAEI 1741

Query: 2096 NSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEV------------------ 1971
              L+   Q     + + +D   +L +E E   Q +    AE+                  
Sbjct: 1742 EQLKQTVQQSDQTIAEKEDLIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQTISQRD 1801

Query: 1970 DAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSL---KAELH 1800
            ++I+ +  E+++  QT+ D  +   +       R N++      +E   +++    AE+ 
Sbjct: 1802 ESIKQMQSEIEQNKQTIADREKEIEQHKQTIAERDNSIKQLQEEIEQHKQTIAERDAEIQ 1861

Query: 1799 LQAQKAFQIQEERNVVESEHN-------VLSSEVENLKSELKESKD-----------LEG 1674
               ++  Q  E  N + +E          L +  ENL +++KE  D              
Sbjct: 1862 KNKEEIQQKNEAINALTNEGEEKRLKILELEANNENLINKVKELNDSVSDLNLSTENQNS 1921

Query: 1673 YFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYE 1494
               ++ + +   + ++  L+++S    ++K +   D+ I     N K +NE L +    E
Sbjct: 1922 VVKQMTDEIKDLNKQIHELEVKSEN--QQKQIEEKDKEI-QSLTNTKAQNEELIKKLQEE 1978

Query: 1493 RKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEED-----SSGVDLLKNKCTRLEFQVQ 1329
             +N++ ++ +    +  K+L     +  E +N+ ED        +  L N     E  ++
Sbjct: 1979 VENLTNTKNQNEETI--KNLQEQVQSLTETKNQNEDLIKKQQEQIQSLTNTKNENEETIK 2036

Query: 1328 KLSEKAE-MFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSL---KKENTR 1161
             L E+ + + ETK+   + +     E+Q                   ++SL   K EN  
Sbjct: 2037 NLQEQVQSLTETKATNEETIKKLQGEVQSLTETKATNEEQIKKQQEEIQSLSNTKNENEE 2096

Query: 1160 LRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQE 981
            L  +++ E+    + K +    IK++    ++                 K+ T +S + E
Sbjct: 2097 LIKKLQEEIQNLTNTKTQNEEQIKKLQEEIQNLQKQNAEKDDKINEFNAKLSTLSSSSDE 2156

Query: 980  IDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEK 801
            + T   + +   N ++  TKQ     N + +L Q                    ++ +E 
Sbjct: 2157 LTTKFINAQ---NEINQLTKQNNEKDNLISQLNQ-------------------KISDLEN 2194

Query: 800  QLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHD-LNGQEQKLKVDEEVPILCHQNSK- 627
               +L     QL++  T L+++       A  +    N +E+K K++ E   L  + +K 
Sbjct: 2195 AKSQLENEKSQLIQEKTNLEQEK------AQLLEQKKNLEEEKQKLETEKTNLEQEKAKL 2248

Query: 626  IAERLDINTDKARALD----MEVQRIRLILSRIPTKPTEEASKM 507
            I E+ ++  +KA+ ++    +E ++ +LI  +  T   +E +K+
Sbjct: 2249 IEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEK--TNLEQEKAKL 2290



 Score = 92.4 bits (228), Expect = 1e-15
 Identities = 173/891 (19%), Positives = 358/891 (40%), Gaps = 48/891 (5%)
 Frame = -3

Query: 3089 LLESCVVDREAHIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEE 2910
            LL+  + D    +K++ME       E + +    +  E+  Q L+ ++         YE 
Sbjct: 994  LLKQRLNDSNNQLKEIME-----TPENKRIAAKEKELEDFQQQLRSQIISQSSSFITYEN 1048

Query: 2909 EKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQEN---------E 2757
            E           +A++Q  E+   ++  N +    KDN I+ L+  L  +         +
Sbjct: 1049 ES----------DAMKQIKEENYRRVVENTH----KDNEIIRLTKLLATDKTLKEDKILQ 1094

Query: 2756 EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQ 2577
            E+   L+  +Q ++  +  +    E  N +   L+D++N LKE +    D++A  +K+L 
Sbjct: 1095 EKIMQLEAKVQQMKDFNKETAANLESKNLENYNLQDNINSLKEQIQKQNDEQANHQKELD 1154

Query: 2576 DLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLE-LEIEKLY 2400
            + + Q   + KE+      E +     + +S+++ +  N  L   E   ++E   I K  
Sbjct: 1155 ERDEQIAVLQKEIE---KYENRYLEQQEVISQEKLNNSNLKLKLNEAENEIEKSHIVKQP 1211

Query: 2399 GSLQMKQMENTLLKDGNE-KIYD-LCKLLATKSREVQGQQEGILKQDINIEDELARTKEV 2226
            G L + ++   +    N+ KI + +      K +E++ Q E   KQ  + E    +++E+
Sbjct: 1212 GELYLSEVPQQISYFENKVKIMNGMITQSNAKIKELESQIEKKNKQIESTEALQKKSREL 1271

Query: 2225 GRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQM 2046
             R   D ++  S  G  V  I EM + +K+    +K +         +D +  +  LE  
Sbjct: 1272 YRQIRDYEQRLSSLGLTVEQIREMEMTIKNQANIIKAK--------DDDLKQTKEILEYR 1323

Query: 2045 QDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARL 1866
            ++   +  AE+      +  L+  +  ++ +L +  ++N     E Q   ++     A+ 
Sbjct: 1324 EEQIEKFIAESVSIRDAIETLKQRISELEMLLEKKDKENNDKIAEIQEENRQTLEQLAKQ 1383

Query: 1865 NNVMSKNIN-LESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVL---SSEVENLKSEL 1698
                 ++IN LE   +  + E+   A+K  QI++  N ++S   V+   S+ +++LK ++
Sbjct: 1384 LQEAEEDINVLEGNCQVYEQEI---AEKDKQIEQMTNDIKSLEEVINEQSNTIDSLKQDV 1440

Query: 1697 ----KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEE-----KLMRILDELI-CLR 1548
                +E K L+       E++     ++   D E  +  EE     + +   DE I  L+
Sbjct: 1441 ATKEEEIKQLKQTVSENEEVIKQLQTDIEQKDAEIQKNKEEIEQHKQTISQRDETIKQLQ 1500

Query: 1547 NENAKLKNEALYEYHDYER-KNVSGSRAEAMSVL---ISKSLGNGRANQREFQ-NKEEDS 1383
            +E  + K     + ++ E+ KN    R E +  L   I +          E Q NKEE  
Sbjct: 1501 SEIEQHKQTIADKNNEIEQLKNTISEREETIKQLQNEIEQHKQTMAERDAEIQKNKEEIE 1560

Query: 1382 SGVDLLKNKCTRLEFQVQKLSEK-AEMFETKSREAQ------QMANKLEEMQQTLSDMXX 1224
                 + N    +E   + +SE+ AE+ + K   A+      Q+ N++E+ +QT+S    
Sbjct: 1561 QQKQTISNNNNEIEQLKKTISERDAEIEQLKKTIAERDESIKQLQNEIEQHKQTISQRDA 1620

Query: 1223 XXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSR---SFKHREGSFIKE-INIGDEDDTP 1056
                      +      E   L  +++ E+   +   S K+ E   +K+ +N  DE    
Sbjct: 1621 EIEQLKQTVQQRDQTIAEKEDLIKQLQSEIEQHKQTISDKNNEIEQLKQTVNARDE---- 1676

Query: 1055 LIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQX 876
             I+            I  R +E Q+    ++  ++    +S   +  + LQN +++ +Q 
Sbjct: 1677 AIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQ---TISQRDETIKQLQNEIEQHKQT 1733

Query: 875  XXXXXXXXXXXXXKWGGIDMNSIEKQ------LKELNIHVMQLVEHNTRLKKDVKFGFAW 714
                              D    EK+        E+  H   + E +  ++K+ +     
Sbjct: 1734 ISQRDAEIEQLKQTVQQSDQTIAEKEDLIKQLQSEIEQHKQTIAERDAEIQKNKE----- 1788

Query: 713  ANSMHDLNGQEQKLKVDEEVPILCHQNSKIAERLDINTDKARALDMEVQRI 561
                     ++QK  + +    +    S+I +      D+ + ++   Q I
Sbjct: 1789 -------EIEQQKQTISQRDESIKQMQSEIEQNKQTIADREKEIEQHKQTI 1832



 Score = 91.7 bits (226), Expect = 2e-15
 Identities = 189/895 (21%), Positives = 356/895 (39%), Gaps = 74/895 (8%)
 Frame = -3

Query: 2972 ISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNI 2793
            + QSLK    ++    R  +++ Q+  ELQ      +++   +  K+++    L  KD  
Sbjct: 3255 LEQSLKVSKNEVDATKRELQKQLQNNKELQNQIKMTKEQFAKLEAKLQSVVKKLNDKDQR 3314

Query: 2792 IVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMA 2613
            I  L      N +Q + L   +  +   +   +T  + + R+   L+DD+   K   S  
Sbjct: 3315 IDSLMSS-DPNNKQTNQLNKQISDLNLENEKLKTRVDIITRENQSLKDDLESQKSQKSKL 3373

Query: 2612 VDDRAFMEKQL---QDLENQKETVSKELALSVSREQKLASDLKAL--SEKEESTKNQLLI 2448
             +    ++ +L   + + +Q +   KEL   ++ + K  S+LKA      +E  K+ + +
Sbjct: 3374 DESCNALKTELINKKSIMDQYKEKLKELMEQINLKNKQISELKAEFNGSDDEDRKSYVKV 3433

Query: 2447 QTEQNKQLELEI-----EKLYGSLQMKQME-NTLLKDGNEKIYDLCKLLATKSREVQGQQ 2286
              ++ +  EL++     +K  G  +MK  +    LK+ N++   + K L T   E++ + 
Sbjct: 3434 IEQEGEITELKVIIDRQKKFVGQQKMKIADLEKNLKESNDEAQKMTKNLQTTIYELEDRC 3493

Query: 2285 EGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVL 2106
            + + +    IE +  R +E  ++  D+ K       K+  IL   + M  D  S K+ ++
Sbjct: 3494 QNLNQ---TIEMKNFRLRENEKTIEDLNKEIEFLKGKID-ILSREISMYSDNSS-KDNLI 3548

Query: 2105 GNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQ 1926
              I SL+   + V    EQ+ D K       EI      ++Q E+D     +  L+ + +
Sbjct: 3549 SKIVSLQ---KTVSEKDEQLNDAKINSNNSLEIED----KMQQEIDQKNSRIHHLENQMR 3601

Query: 1925 TLQDE-SQRNAKE-------LWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQ 1770
             L ++ S  NAKE       L  A  +L+N+ +   +L+ +N +LK+++        + Q
Sbjct: 3602 VLLNKASHENAKEESKVKIDLKKANVKLSNLENDFSSLQEENAALKSKVSKLELVIKEKQ 3661

Query: 1769 EERNVVESEHNVLSSEVENLKSELK--------ESKDLEGYFLRLFEILLGQHVEVASLD 1614
             E N++  ++N   +E+  LKS+L+        E    E     + ++      +   LD
Sbjct: 3662 SEINIMAQKNNNDINEISELKSKLRKQNEDFTQEKSSAEKQRSEIDQLTNDLKAKNNELD 3721

Query: 1613 --IESCRFAEEKLMRILDELIC----LRNENAKLKN-EALYEYHDYERKNVSGSRAEAMS 1455
                  R  + K+ ++  +       L+ E+ KL   E   +  + E  N S    +A  
Sbjct: 3722 DSKSEIRILKSKINQLQQDFDAKNHSLQKESEKLSQLEEKMKEKELELLNKSLDNDKAAK 3781

Query: 1454 VLISKSLGNGRANQREFQNKEEDSSGV-----DL------LKNKCTRLE---FQVQKLS- 1320
             +I K         ++ + KE+D   +     DL      LK K   L+    Q+ K S 
Sbjct: 3782 EIIEKLQNENLEQSKQLKKKEKDIEQMKQILNDLNNEQGELKGKIMTLQNDNEQITKTSQ 3841

Query: 1319 EKAEMFETKSREAQQMANKLE---------------EMQQTLSDMXXXXXXXXXXXIRVR 1185
            EK ++ E KS E   M NKL                + ++ ++ +            R+ 
Sbjct: 3842 EKFKLNEKKSEELVSMINKLNDEIAEKNKTINGTLLQKEKEITKLKNDLEQSQITNERIT 3901

Query: 1184 SLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQ--XXXXXXXXXXXK 1011
            +L+ E  +++ ++  +L    +  + E   I++ N   E    LIQ              
Sbjct: 3902 NLESEMMKMK-QLNDDLMNDINRYNEE--LIEKENELQELREKLIQSGNNLQKVTPEQSY 3958

Query: 1010 IDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKW 831
             D +   T+  D + D N +  N+ +  T     L N+                      
Sbjct: 3959 FDLQMKITELEDIIKDKNSQLENKTNEITNLYSKLYNTSPPSNSKKPRNTKLEVEKMR-- 4016

Query: 830  GGIDMNSIEKQLKEL-------NIHVMQLVEHNTRLKKDVKFGFAWANS-MHDLNGQEQK 675
              I M  +E + K+L       N  +   +  N +LK+ +K      NS ++ LN + QK
Sbjct: 4017 --IKMAELENKNKDLIDQNTRMNSDLQAQINQNNKLKRHMKDNENNFNSQINQLNLKLQK 4074

Query: 674  LKVDEEVPILCHQNSKIAERLDINTDKARALDMEVQRIRLILSRIPTKPTEEASK 510
            +  D E  +L   NSK                 + QR+  +  RI  K  E  SK
Sbjct: 4075 VVSDYEARLLILDNSK----------------NQTQRVNELRERIKQKNEEILSK 4113



 Score = 86.3 bits (212), Expect = 8e-14
 Identities = 196/994 (19%), Positives = 400/994 (40%), Gaps = 118/994 (11%)
 Frame = -3

Query: 3188 QKKAGELQTKVHIREEE--SCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNA-LV 3018
            Q+   +LQ  +  ++ E    K   EA  N      L+    +  A +++ +EQ+ A L 
Sbjct: 2892 QQAIDDLQNNLKQKDAELTDTKQKLEAKTNEFND--LKQKAENEIASLRKEIEQLKAKLA 2949

Query: 3017 KEKRELE-----NDAQRGEEISQSLKDEVFQLKEVSR-LYEEEKQHTIELQENFNALRQK 2856
               +ELE     +D Q+ E  +  LK  + ++ E+ + L  E + ++ +  +    +++K
Sbjct: 2950 NTSKELEASKSESDLQKKE--NDKLKVNLAKIAEMYKTLKSESENNSAKSNDKIKQMQEK 3007

Query: 2855 NEDICLKIE----ANNNLLEQ---KDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVS 2697
             +++ +++E    AN NL  +   +   I  L+ KL E+ +  +A   + +++++ + + 
Sbjct: 3008 IQNLEIQVEKMKLANENLTNENKLQKETIEMLNKKLLESNKSLTASIKEYETLKRENNLQ 3067

Query: 2696 QTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSRE 2517
            + +  +L  Q+  L  D   LK+       ++A ++ +L +L +      KE+    S  
Sbjct: 3068 KDQITKLTSQVQKLTQDFTQLKK-------EKAEVDSKLNELLDLLAQKDKEIERLKSEN 3120

Query: 2516 QKL----ASDLKALSEKEESTKNQ-------LLIQTEQNKQLE---LEIEKLYGSLQMKQ 2379
            QKL        K L EKE   ++Q       L +  ++NK++E   +  + L  SL   Q
Sbjct: 3121 QKLNELYQQITKDLEEKEFLIQSQNNRCIDLLNLTEKKNKEIETLQISNDSLNNSLTKSQ 3180

Query: 2378 ME----NTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRS-- 2217
            ME    +TLL++  +KI +  + LA   R      E      +N+       K+      
Sbjct: 3181 MELREKSTLLENAKDKITESNRKLALFDRLSANSSE------LNLTSSGRGIKKSSSMNL 3234

Query: 2216 ATDM---KKVNSDAGAKVSGILEMLLPMKDDVFSLKEEV---LGNINSLRNDAQMVQVAL 2055
            +TDM    K+ +     + G+ + L   K++V + K E+   L N   L+N  +M +   
Sbjct: 3235 STDMDSKNKIINQQEQTIIGLEQSLKVSKNEVDATKRELQKQLQNNKELQNQIKMTKEQF 3294

Query: 2054 EQMQDTKSELFAEAEIRAQEVLRLQA------EVDAIQHILIELKRKNQTLQDESQRNAK 1893
             +++     +  +   + Q +  L +      + + +   + +L  +N+ L+       +
Sbjct: 3295 AKLEAKLQSVVKKLNDKDQRIDSLMSSDPNNKQTNQLNKQISDLNLENEKLKTRVDIITR 3354

Query: 1892 ELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVEN 1713
            E  + K  L +  S+   L+    +LK EL  +     Q +E+   +  + N+ + ++  
Sbjct: 3355 ENQSLKDDLESQKSQKSKLDESCNALKTELINKKSIMDQYKEKLKELMEQINLKNKQISE 3414

Query: 1712 LKSELKESKDLEGYFLRLFEILLGQHVEVASLDI---ESCRFAEEKLMRILDELICLRNE 1542
            LK+E   S D +    + +  ++ Q  E+  L +      +F  ++ M+I D    L+  
Sbjct: 3415 LKAEFNGSDDEDR---KSYVKVIEQEGEITELKVIIDRQKKFVGQQKMKIADLEKNLKES 3471

Query: 1541 N------AKLKNEALYEYHD--------YERKNVS------------------GSRAEAM 1458
            N       K     +YE  D         E KN                      + + +
Sbjct: 3472 NDEAQKMTKNLQTTIYELEDRCQNLNQTIEMKNFRLRENEKTIEDLNKEIEFLKGKIDIL 3531

Query: 1457 SVLISKSLGNGRAN---------QREFQNKEEDSSGVDLLKNKCTRLEFQVQK-LSEKAE 1308
            S  IS    N   +         Q+    K+E  +   +  N    +E ++Q+ + +K  
Sbjct: 3532 SREISMYSDNSSKDNLISKIVSLQKTVSEKDEQLNDAKINSNNSLEIEDKMQQEIDQKNS 3591

Query: 1307 MFETKSREAQQMANKL-----EEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEM- 1146
                   + + + NK      +E  +   D+               SL++EN  L+S++ 
Sbjct: 3592 RIHHLENQMRVLLNKASHENAKEESKVKIDLKKANVKLSNLENDFSSLQEENAALKSKVS 3651

Query: 1145 KGELTPSRSFKHREGSFIKEINIGDEDD-TPLIQXXXXXXXXXXXKIDTRTSETQEIDTL 969
            K EL      K  E + + + N  D ++ + L             +  +   +  EID L
Sbjct: 3652 KLELVIKE--KQSEINIMAQKNNNDINEISELKSKLRKQNEDFTQEKSSAEKQRSEIDQL 3709

Query: 968  MDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKE 789
             +D +   N +     + + L++ + +LQQ              K   ++    EK+L+ 
Sbjct: 3710 TNDLKAKNNELDDSKSEIRILKSKINQLQQDFDAKNHSLQKESEKLSQLEEKMKEKELEL 3769

Query: 788  LN------------IHVMQ--LVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEEVP 651
            LN            I  +Q   +E + +LKK  K        ++DLN ++ +LK   ++ 
Sbjct: 3770 LNKSLDNDKAAKEIIEKLQNENLEQSKQLKKKEKDIEQMKQILNDLNNEQGELK--GKIM 3827

Query: 650  ILCHQNSKIA----ERLDINTDKARALDMEVQRI 561
             L + N +I     E+  +N  K+  L   + ++
Sbjct: 3828 TLQNDNEQITKTSQEKFKLNEKKSEELVSMINKL 3861



 Score = 74.7 bits (182), Expect = 2e-10
 Identities = 162/794 (20%), Positives = 308/794 (38%), Gaps = 72/794 (9%)
 Frame = -3

Query: 3050 KQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQ--------------LKEVSRLYE 2913
            ++L   +NAL   K  L N++    EISQ+  D +                L E  +LY 
Sbjct: 141  QKLRNLVNALESLKNNLTNESIITHEISQNDGDTLISRNVINTNASFAAELLNENEKLYL 200

Query: 2912 EEKQHTIELQENFNALRQKNEDICLKIEAN---------NNLLEQKDNIIVE--LSHKLQ 2766
            E +     L +  N LR KN  I ++IE +         + L E  +N I++  L  KLQ
Sbjct: 201  ENR----SLLQLKNELRAKNLKI-IQIENDFRNRLRKYKHKLDELSNNEILDNILREKLQ 255

Query: 2765 ENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEK 2586
              +  +S  Q     +          R   N    L   D N L+  L    +    + K
Sbjct: 256  TRDMVQSVAQEQYAILHNFEVSKSLTRPNGNNSSNLHELDNNQLQGELIKLREQILELSK 315

Query: 2585 QLQDLENQKETV---SKELALSVSREQKLASDLKALSEK---------EESTKNQLLIQT 2442
            Q  + E++ E V   +K L    S  Q++   L  L +K         EE T  + L ++
Sbjct: 316  QKSETESKLEWVEQSNKLLQSKPSENQQILDQLNTLRQKEIDEQQKHVEELTNQEKLAES 375

Query: 2441 EQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDI 2262
            E  KQ++  ++KL  S    + EN  L+  N  + D  +L A  S +   + E IL  + 
Sbjct: 376  EYQKQID-HLKKLLESSNAAETEN--LRKENNNLRD--QLAAIASNKNILENEEILTSNF 430

Query: 2261 NIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRN 2082
            ++ D++   K + R   +  K   +  +++      +  +K DV   KE  + ++ +  N
Sbjct: 431  DLSDKVDELKSIIR---NKDKQIIELESEIDNQKATIEDLKIDV-DFKERTISDLENKIN 486

Query: 2081 DAQMVQVALEQMQDTKSELFA--EAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDES 1908
             +      +E +++ K +  +  + +I  Q  + +Q   + I  +  +++ K+Q + +  
Sbjct: 487  VSANPDKGIELLKEEKDKAISKLQKQIERQNTI-IQQNEEKIDQLSKDIEAKDQKIDEMI 545

Query: 1907 QRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQ---KAFQIQEERNVVESEHN 1737
            Q++      A+    +  +  + L++ N  +  +     Q   K  Q+++ER   +++ +
Sbjct: 546  QKSL----TAEVPSGDGAALELKLQNLNSYIAIQNEKMGQKDAKIEQLEDERQKNDTKIS 601

Query: 1736 VLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELI 1557
             L+S +  LK    E+       L++ E+       +A  +I   +  E  L  +  E+ 
Sbjct: 602  ELTSTLTQLKLTNNENT------LKIAEL----ENTIAKSNIPK-KEGELYLSEVPQEVS 650

Query: 1556 CLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSG 1377
             L+N+N  L              N++ S+AE +  L           ++E   K +    
Sbjct: 651  FLKNKNNML-------------NNINKSQAEKIKHL-----------EQEIVKKNKQIGS 686

Query: 1376 VDLLKNKCTRLEFQVQKLSEK--AEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXX 1203
            +D +  K   L+ Q+Q    K  A+  E+    + ++ + L++    L+ +         
Sbjct: 687  IDEMHKKSRELQRQIQDYENKLNAQQLESGGENSAELLS-LKQQSNLLNQL--------- 736

Query: 1202 XXIRVRSLKKENTRLR------------------------SEMKGELTPSRSFKHREGSF 1095
                V  LKK+N  L+                        SE+  EL       H     
Sbjct: 737  ----VADLKKQNIELKKTLETKDKQLSSMMSDSLLVKDNLSEITAELASKNKIIHDYELR 792

Query: 1094 IKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQ----EIDTLMDDNRKYWNRVSHF 927
            +  ++        L+Q           +I+T  S+ +    EI TL  D       +   
Sbjct: 793  LNALSGSGNQFENLLQEKLTKIATMEKRINTMKSDIEKQKIEIATLNQDVSDKNKTIQQL 852

Query: 926  TKQTQSLQNSVQEL 885
              + ++ +NSVQ L
Sbjct: 853  QNKLKNKENSVQRL 866



 Score = 71.6 bits (174), Expect = 2e-09
 Identities = 134/674 (19%), Positives = 278/674 (41%), Gaps = 26/674 (3%)
 Frame = -3

Query: 3227 AQHQKILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIK 3048
            +++Q+IL+    L++K            +E  KH+ E         L ES    +  H+K
Sbjct: 339  SENQQILDQLNTLRQK----------EIDEQQKHVEELTNQE---KLAESEYQKQIDHLK 385

Query: 3047 QLMEQMNALVKEKRELENDAQR--------------GEEISQS---LKDEVFQLKEVSRL 2919
            +L+E  NA   E    EN+  R               EEI  S   L D+V +LK + R 
Sbjct: 386  KLLESSNAAETENLRKENNNLRDQLAAIASNKNILENEEILTSNFDLSDKVDELKSIIR- 444

Query: 2918 YEEEKQHTIELQENFNALRQKNEDICLKIEANNNL---LEQKDNIIVELSHKLQ-ENEEQ 2751
              ++KQ  IEL+   +  +   ED+ + ++        LE K N+       ++   EE+
Sbjct: 445  -NKDKQ-IIELESEIDNQKATIEDLKIDVDFKERTISDLENKINVSANPDKGIELLKEEK 502

Query: 2750 RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDL 2571
              A+    + +E+ + + Q   E++++    L  D+    EA    +D            
Sbjct: 503  DKAISKLQKQIERQNTIIQQNEEKIDQ----LSKDI----EAKDQKID------------ 542

Query: 2570 ENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSL 2391
                E + K L   V      + D  AL  K ++  + + IQ E+  Q + +IE+L    
Sbjct: 543  ----EMIQKSLTAEVP-----SGDGAALELKLQNLNSYIAIQNEKMGQKDAKIEQLEDE- 592

Query: 2390 QMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSAT 2211
              +Q  +T + +    +  L       + ++   +  I K +I  ++      EV +  +
Sbjct: 593  --RQKNDTKISELTSTLTQLKLTNNENTLKIAELENTIAKSNIPKKEGELYLSEVPQEVS 650

Query: 2210 DMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKS 2031
             +K  N+          E +  ++ ++   K + +G+I+ +   ++ +Q    Q+QD ++
Sbjct: 651  FLKNKNNMLNNINKSQAEKIKHLEQEIVK-KNKQIGSIDEMHKKSRELQ---RQIQDYEN 706

Query: 2030 ELFAE----AEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLN 1863
            +L A+        + E+L L+ + + +  ++ +LK++N  L+       K L     +L+
Sbjct: 707  KLNAQQLESGGENSAELLSLKQQSNLLNQLVADLKKQNIELK-------KTLETKDKQLS 759

Query: 1862 NVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSE-LKESK 1686
            ++MS ++ ++     + AEL  + +     +   N +    N    + ENL  E L +  
Sbjct: 760  SMMSDSLLVKDNLSEITAELASKNKIIHDYELRLNALSGSGN----QFENLLQEKLTKIA 815

Query: 1685 DLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEY 1506
             +E     +   +  Q +E+A+L+ +           + D+   ++    KLKN+     
Sbjct: 816  TMEKRINTMKSDIEKQKIEIATLNQD-----------VSDKNKTIQQLQNKLKNK----- 859

Query: 1505 HDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQK 1326
             +   + ++G   +  S          R ++ E  N+ +      LL NK  + + Q++ 
Sbjct: 860  -ENSVQRLNGEITDLRS----------RISEYEILNERQAKENA-LLNNKLKQKDVQIEN 907

Query: 1325 LSEKAEMFETKSRE 1284
            + E+ +  E K ++
Sbjct: 908  IKEQPKEEEEKPKQ 921


>ref|XP_006560777.1| PREDICTED: sporulation-specific protein 15 isoform X2 [Apis
            mellifera]
          Length = 1934

 Score =  133 bits (334), Expect = 6e-28
 Identities = 190/894 (21%), Positives = 380/894 (42%), Gaps = 32/894 (3%)
 Frame = -3

Query: 3143 EESCKHLTEALE--NHIYGSLLESCVVDREAHIKQLMEQMNALVKEKRELENDAQRGEEI 2970
            E++  +LT+ LE  N+   +L +   +++ A +K L EQ+  +   K++L+   ++  ++
Sbjct: 129  EQTVANLTKELEEKNNKIDALKKE--LEQMAILKSLEEQIAIM---KQDLKKKDEKISDL 183

Query: 2969 SQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEA-NNNLLEQKDNI 2793
              +L+     L  +  L  + +    EL E    LR+  E+I  ++    + L E+ D I
Sbjct: 184  LNTLRQSEINLLGLEGLKSKLEHLEPELYE----LRESKEEIMEELNMMRDTLKERNDQI 239

Query: 2792 IVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMA 2613
            I  L  K +  E  +S ++     +++  ++S  E E+L  +L    +D     + L   
Sbjct: 240  IQILEDKAKLEEYYKSKVETLEAKLDEQASLS-AELEDLRNEL----EDQRAKNKELEAC 294

Query: 2612 VDDRAFMEKQLQDLENQKETVSKELALS---VSREQKLASDLKALSEKEESTKNQLLIQT 2442
              D   +EK+L +LE ++  + KEL  +   + R QK   DLK + E E + K++L    
Sbjct: 295  CKDMDALEKKLSELEKKRSELEKELEDNRGELERLQKENLDLKDVIEVERAEKDKLRDLL 354

Query: 2441 EQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDI 2262
            E++K+L+ + E L+  L+  + EN  L    + + DL K L   +  ++     +  +  
Sbjct: 355  EESKKLKEDNENLWAQLERLRGENDDLMGQKKALEDLNKQLNEDNESMKRTMGNLEARID 414

Query: 2261 NIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRN 2082
            ++ +EL+  +    +  D  +        V   LE  L   +++ +  ++    ++ L+ 
Sbjct: 415  SLSNELSNVERERDALLDENE-------SVKRELERTLTENENLKTELDKADEQLDKLKT 467

Query: 2081 DAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQR 1902
            +   +Q   + M+        E E   + V  L+ +++  +  + E+K     L+D+ + 
Sbjct: 468  ERNELQRNFDTMK-------LENETLKENVKALKDDLEESKREVDEMKAVGDALKDKEEL 520

Query: 1901 NAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSE 1722
               E    +  + N+ ++N  L+ +N  L+        K   +++E + VESE+  L ++
Sbjct: 521  KDAEFRELQQNMQNLKTENGELKKENDDLRTRSSELEHKLDNVKKELDKVESENADLRAK 580

Query: 1721 VENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNE 1542
            ++NL+ EL++ K               + +E   L+I S + A +K    +DE+  L+ E
Sbjct: 581  IDNLEKELEKDK---------------KEIEQLKLEISSLKDALDK---CVDEMEKLKVE 622

Query: 1541 NAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLK 1362
            N KLK E +     +  +NV                 N +A   E +           L 
Sbjct: 623  NEKLKKEGMKVEATWLEENV-----------------NLKAKNTELEEN---------LA 656

Query: 1361 NKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRS 1182
            N    L+   +  SE A++    +R  Q++ +  +E+ Q  S++             +  
Sbjct: 657  NTVNELD---KMRSENADLLSELNRLKQELESGRKEIDQLKSEIGSMKDALGKCVDEIEK 713

Query: 1181 LKKENTRLRSEMKGELTPSRSFKHREGSFIK----EINIGDEDDTPLIQXXXXXXXXXXX 1014
            LK EN  L+SE++G L   R     E + +K    E+     D +  +            
Sbjct: 714  LKTENKDLKSEVQG-LESERDRLTNEVADLKPKISELQEKLTDASKKLDEAKTEDSDLRA 772

Query: 1013 KIDTRTSETQ----EIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXX 846
            ++D    E +    EID L  +     N ++   ++ + L N   EL+            
Sbjct: 773  EVDRLKKELESAGKEIDQLKAEMNSLKNGLNKCVEEMEKLTNENSELKSQVHGLRGEGDS 832

Query: 845  XXXKWGGI-DMNS--------IEKQLKE-------LNIHVMQLVEHNTRLKKDVKFGFAW 714
               +   + D NS        + KQL E       L     +L   NT++KK+++     
Sbjct: 833  LASELTNVKDENSALKDEKDQLNKQLAENKTENERLKKQNDELESENTKIKKELESCKNE 892

Query: 713  ANSMHDLNG--QEQKLKVDEEVPILCHQNSKIAERLDINTDKARALDMEVQRIR 558
             N++ + N   +E+  K+ E++  L  + +K+   L    DK + L+ ++ R R
Sbjct: 893  NNNLKEENNKLKEELEKLGEQLKSLNDETNKLRRELKEAEDKIQILEPQLSRAR 946



 Score =  121 bits (304), Expect = 2e-24
 Identities = 203/985 (20%), Positives = 405/985 (41%), Gaps = 87/985 (8%)
 Frame = -3

Query: 3215 KILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLME 3036
            K +++   L+ +  +L+++V   E E  +   E  +     S L+  + D    + +   
Sbjct: 706  KCVDEIEKLKTENKDLKSEVQGLESERDRLTNEVADLKPKISELQEKLTDASKKLDEAKT 765

Query: 3035 QMNALVKE----KRELENDAQRGEEISQSLKDEVFQLKE-VSRLYEEEKQHT---IELQE 2880
            + + L  E    K+ELE+    G+EI Q LK E+  LK  +++  EE ++ T    EL+ 
Sbjct: 766  EDSDLRAEVDRLKKELES---AGKEIDQ-LKAEMNSLKNGLNKCVEEMEKLTNENSELKS 821

Query: 2879 NFNALRQKNEDICLKI----EANNNLLEQKDNIIVELSHKLQENE--------------- 2757
              + LR + + +  ++    + N+ L ++KD +  +L+    ENE               
Sbjct: 822  QVHGLRGEGDSLASELTNVKDENSALKDEKDQLNKQLAENKTENERLKKQNDELESENTK 881

Query: 2756 --EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQ 2583
              ++  + +N+  ++++ +   + E E+L  QL  L D+ N L+  L  A D    +E Q
Sbjct: 882  IKKELESCKNENNNLKEENNKLKEELEKLGEQLKSLNDETNKLRRELKEAEDKIQILEPQ 941

Query: 2582 LQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKL 2403
            L    ++ E    ELA+  +   +L   L        + +N L I  +Q   L  +++  
Sbjct: 942  LSRARSENEKSQNELAVLRNEANELKVKLDREMLDNTNMRNALKILEDQVLDLNKKLDNC 1001

Query: 2402 YGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIED---ELA-RT 2235
                   + EN   KD   K+ D  +++     E    +E I      IE    ++A + 
Sbjct: 1002 REENDALKEEN---KDLKTKLSDTGQVVLNLKTECDNLKEDIASLQKTIEQLKQKIADQE 1058

Query: 2234 KEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVAL 2055
             E+     +  K   D   K+   LE +L   ++    K+ +  ++  L+N+   +   +
Sbjct: 1059 AEIDHWKVEHCKFELD-NEKLKADLEKVLKDLNECQIAKKAIESDLIKLKNEKDDLNKNM 1117

Query: 2054 ----EQMQDTKSELFAEAEIRAQ---EVLRLQAEVDAIQHILIELKRKNQTLQDESQRNA 1896
                 Q+   K  L AE   + +   ++  L +E++A++  L +L+  N   + E     
Sbjct: 1118 TDLTSQLDRQKRSLEAEKSAKDRGDVQIASLNSELEALKKELEKLRADNSKYKSEIDDLG 1177

Query: 1895 KELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVE 1716
            K+L +AK  LN+   + + L++ N +L++EL           +    ++ +++ L++E++
Sbjct: 1178 KQLASAKNELNDCREEIVVLKNANSALRSEL-----------DPLRSLKDDYSRLTTELD 1226

Query: 1715 NLKSE----LKESKDLEGYFLRLFEILLGQHVEVASL----------------DIESCRF 1596
             LKSE    L++ + LE  F +L     GQ VE+  L                D++SC+ 
Sbjct: 1227 GLKSENTKLLQDKRSLEDEFGKLRGEGDGQRVEIDRLRTTLDAEKTAAEKLKSDLQSCKD 1286

Query: 1595 AEEKLMRILDE----LICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVL------- 1449
              +KL   ++E    L  +  EN +LK E      D  RK +    A+  S+        
Sbjct: 1287 ENDKLQTQINEMKRSLDKMGTENDRLKREV-----DESRKKLEDMEAKVKSLENQLSNLS 1341

Query: 1448 -----ISKSLGNGRANQREFQNKEEDSSGV-DLLKNKCTRLEFQVQKLSEKAEMFETKSR 1287
                 + K L   R +    +N+ E  +GV D ++ + T L+ +++ L E+      ++ 
Sbjct: 1342 AEKEELVKELYRTREDLNNLRNELEKQTGVKDTMEKESTNLKEELKALKEELNKTRDEND 1401

Query: 1286 EAQQMANKLE-EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK-------GELT 1131
              +   +KL  E+ +    +             + +L + N  L  E+        G  T
Sbjct: 1402 RLKNENDKLNAEIARLNKQLDALKDESANLKNDIENLNERNAELSKELAVAKDNLMGMET 1461

Query: 1130 PSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRK 951
               + K +E   +K   I  ED    +            ++D     + E+DTL   N+K
Sbjct: 1462 RLSNLK-KENDDMKNKIITLEDSIQEVDDLKRQLKEAKKELD---KPSPELDTLKSTNKK 1517

Query: 950  YWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMN--SIEKQLKELNIH 777
              + + +   ++ +L+N +  LQ               +         ++EK L  +   
Sbjct: 1518 LQDDLDNARNESLNLKNDLDNLQNDYNNLQTELADVKEERDTFRERAAALEKDLVRVKRE 1577

Query: 776  VMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEEVPILCHQNSKIAERLDINTD 597
              +LVE N  L+ +          + D  G+  +L   +E+  L  +N K+ + L     
Sbjct: 1578 NEELVEQNETLRTE----------LDDCRGENNRLL--KELEKLKSENVKLQDNLINARS 1625

Query: 596  KARALDMEVQRIRLILSRIPTKPTE 522
            +   L  ++ +++   S + T  T+
Sbjct: 1626 EGERLKEDLNKLKKDYSDLRTDLTK 1650



 Score =  112 bits (280), Expect = 1e-21
 Identities = 189/949 (19%), Positives = 388/949 (40%), Gaps = 60/949 (6%)
 Frame = -3

Query: 3227 AQHQKILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYG-----SLLESCVVDR 3063
            A+ +++ ++   L+ + GEL+     +E +  +  +  LE+ +         +ES   D 
Sbjct: 523  AEFRELQQNMQNLKTENGELK-----KENDDLRTRSSELEHKLDNVKKELDKVESENADL 577

Query: 3062 EAHIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEE--KQHTIE 2889
             A I  L +++    KE  +L+ +    ++      DE+ +LK  +   ++E  K     
Sbjct: 578  RAKIDNLEKELEKDKKEIEQLKLEISSLKDALDKCVDEMEKLKVENEKLKKEGMKVEATW 637

Query: 2888 LQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQM 2709
            L+EN N L+ KN +          L E   N + EL     EN +  S L    Q +E  
Sbjct: 638  LEENVN-LKAKNTE----------LEENLANTVNELDKMRSENADLLSELNRLKQELE-- 684

Query: 2708 HAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDD-------RAFMEKQLQDLENQKETV 2550
                 + R+E+++    L+ ++  +K+AL   VD+          ++ ++Q LE++++ +
Sbjct: 685  -----SGRKEIDQ----LKSEIGSMKDALGKCVDEIEKLKTENKDLKSEVQGLESERDRL 735

Query: 2549 SKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMEN 2370
            + E+A    +  +L   L   S+K +  K +      +  +L+ E+E     +   + E 
Sbjct: 736  TNEVADLKPKISELQEKLTDASKKLDEAKTEDSDLRAEVDRLKKELESAGKEIDQLKAEM 795

Query: 2369 TLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNS 2190
              LK+G  K  +  + L  ++ E++ Q  G+  +  ++  EL   K+   +  D K   +
Sbjct: 796  NSLKNGLNKCVEEMEKLTNENSELKSQVHGLRGEGDSLASELTNVKDENSALKDEKDQLN 855

Query: 2189 DAGAKVSGILEMLLPMKDDVFS----LKEEV---LGNINSLRNDAQMVQVALEQMQDTKS 2031
               A+     E L    D++ S    +K+E+       N+L+ +   ++  LE++ +   
Sbjct: 856  KQLAENKTENERLKKQNDELESENTKIKKELESCKNENNNLKEENNKLKEELEKLGEQLK 915

Query: 2030 ELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMS 1851
             L  E     +E+   + ++  ++  L   + +N+  Q+E      E    K +L+  M 
Sbjct: 916  SLNDETNKLRRELKEAEDKIQILEPQLSRARSENEKSQNELAVLRNEANELKVKLDREML 975

Query: 1850 KNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSE-------VENLKSELKE 1692
             N N+ +  + L+ ++    +K    +EE + ++ E+  L ++       V NLK+E   
Sbjct: 976  DNTNMRNALKILEDQVLDLNKKLDNCREENDALKEENKDLKTKLSDTGQVVLNLKTECDN 1035

Query: 1691 SKD----LEGYFLRLFEILLGQHVEVASLDIESCRFA--EEKLMRILDELICLRNENAKL 1530
             K+    L+    +L + +  Q  E+    +E C+F    EKL   L++++   NE  ++
Sbjct: 1036 LKEDIASLQKTIEQLKQKIADQEAEIDHWKVEHCKFELDNEKLKADLEKVLKDLNE-CQI 1094

Query: 1529 KNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCT 1350
              +A+ E    + KN      + M+ L S+     R+ + E   K+     +  L ++  
Sbjct: 1095 AKKAI-ESDLIKLKNEKDDLNKNMTDLTSQLDRQKRSLEAEKSAKDRGDVQIASLNSELE 1153

Query: 1349 RLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKE 1170
             L+ +++KL  +A+  + KS E   +  +L   +  L+D              +  LK  
Sbjct: 1154 ALKKELEKL--RADNSKYKS-EIDDLGKQLASAKNELND----------CREEIVVLKNA 1200

Query: 1169 NTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSE 990
            N+ LRS    EL P RS K        E++    ++T L+Q                  +
Sbjct: 1201 NSALRS----ELDPLRSLKDDYSRLTTELDGLKSENTKLLQDKRSLEDEFGKLRGEGDGQ 1256

Query: 989  TQEIDTL---------------------MDDNRKYWNRVSHFTKQTQSLQNSVQELQQXX 873
              EID L                      D+N K   +++   +    +      L++  
Sbjct: 1257 RVEIDRLRTTLDAEKTAAEKLKSDLQSCKDENDKLQTQINEMKRSLDKMGTENDRLKREV 1316

Query: 872  XXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDL 693
                              + S+E QL  L+    +LV+   R ++D+       N +   
Sbjct: 1317 DESRKKLEDME-----AKVKSLENQLSNLSAEKEELVKELYRTREDLN---NLRNELEKQ 1368

Query: 692  NG-----QEQKLKVDEEVPILCHQNSKIAERLDINTDKARALDMEVQRI 561
             G     +++   + EE+  L  + +K  +  D   ++   L+ E+ R+
Sbjct: 1369 TGVKDTMEKESTNLKEELKALKEELNKTRDENDRLKNENDKLNAEIARL 1417



 Score =  109 bits (273), Expect = 7e-21
 Identities = 127/615 (20%), Positives = 285/615 (46%), Gaps = 12/615 (1%)
 Frame = -3

Query: 3044 LMEQMNALVKEKRELEND--AQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFN 2871
            L  +   L+++KR LE++    RGE   Q +     ++  +    + EK    +L+ +  
Sbjct: 1228 LKSENTKLLQDKRSLEDEFGKLRGEGDGQRV-----EIDRLRTTLDAEKTAAEKLKSDLQ 1282

Query: 2870 ALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQT 2691
            + + +N+ +  +I      L++       L  ++ E+ ++   ++  ++S+E   +    
Sbjct: 1283 SCKDENDKLQTQINEMKRSLDKMGTENDRLKREVDESRKKLEDMEAKVKSLENQLSNLSA 1342

Query: 2690 EREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQK 2511
            E+EEL ++L   R+D+N+L+  L          EKQ       K+T+ KE          
Sbjct: 1343 EKEELVKELYRTREDLNNLRNEL----------EKQ----TGVKDTMEKE-------STN 1381

Query: 2510 LASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDG----NEK 2343
            L  +LKAL E+   T+++      +N +L  EI +L   L   + E+  LK+     NE+
Sbjct: 1382 LKEELKALKEELNKTRDENDRLKNENDKLNAEIARLNKQLDALKDESANLKNDIENLNER 1441

Query: 2342 IYDLCKLLATKSREVQGQQ---EGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKV 2172
              +L K LA     + G +     + K++ ++++++   ++  +   D+K+   +A  + 
Sbjct: 1442 NAELSKELAVAKDNLMGMETRLSNLKKENDDMKNKIITLEDSIQEVDDLKRQLKEAKKE- 1500

Query: 2171 SGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEV 1992
               L+   P  D + S  +++  ++++ RN++  ++  L+ +Q+  + L  E     +E 
Sbjct: 1501 ---LDKPSPELDTLKSTNKKLQDDLDNARNESLNLKNDLDNLQNDYNNLQTELADVKEER 1557

Query: 1991 LRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLK 1812
               +    A++  L+ +KR+N+ L ++++    EL + +   N ++ +   L+S+N  L+
Sbjct: 1558 DTFRERAAALEKDLVRVKRENEELVEQNETLRTELDDCRGENNRLLKELEKLKSENVKLQ 1617

Query: 1811 AELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHV 1632
              L     +  +++E+ N ++ +++ L +++   + +    K+ +    +  + L   + 
Sbjct: 1618 DNLINARSEGERLKEDLNKLKKDYSDLRTDLTKAREDRDVRKEKDMELDKEIDELKAVNA 1677

Query: 1631 EVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSV 1452
            ++ S D+  C+   EKL +   ++  L+ EN KLK +AL +  D +   +     +  + 
Sbjct: 1678 KLKS-DLYDCQKENEKLRK---QVTKLKAENDKLK-KALDKDLDQKETEIDKDILDDCNE 1732

Query: 1451 LISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQ--VQKLSEKAEMFETKSR-EA 1281
             +        AN+   +N E    GV  L++    L+ +    K+++K E  E  +   A
Sbjct: 1733 YV-------EANKILRKNFENQLKGVQRLRDYINYLDGKGTEPKMADKLEESEMNNPVNA 1785

Query: 1280 QQMANKLEEMQQTLS 1236
            ++    L +M Q LS
Sbjct: 1786 KKDIEDLLKMSQDLS 1800



 Score = 76.3 bits (186), Expect = 8e-11
 Identities = 101/538 (18%), Positives = 229/538 (42%), Gaps = 21/538 (3%)
 Frame = -3

Query: 3227 AQHQKILEDYYALQKKAGELQTKVHIREEESCKHLT----EALENHIYGSLLESCVVDRE 3060
            +++ K+L+D  +L+ + G+L+ +   +  E  +  T    E        S L+SC  + +
Sbjct: 1230 SENTKLLQDKRSLEDEFGKLRGEGDGQRVEIDRLRTTLDAEKTAAEKLKSDLQSCKDEND 1289

Query: 3059 AHIKQLMEQMNALVKE-------KRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQ 2901
                Q+ E   +L K        KRE++   ++ E++   +K    QL  +S   EE  +
Sbjct: 1290 KLQTQINEMKRSLDKMGTENDRLKREVDESRKKLEDMEAKVKSLENQLSNLSAEKEELVK 1349

Query: 2900 HTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQS 2721
                 +E+ N LR +       +E    + +  +     L  +L+  +E+ +  +++   
Sbjct: 1350 ELYRTREDLNNLRNE-------LEKQTGVKDTMEKESTNLKEELKALKEELNKTRDENDR 1402

Query: 2720 VEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKE 2541
            ++  +     E   LN+QL  L+D+  +LK                +++L  +   +SKE
Sbjct: 1403 LKNENDKLNAEIARLNKQLDALKDESANLK--------------NDIENLNERNAELSKE 1448

Query: 2540 LALSVSREQKLASDLKALSEKEESTKNQLLI---QTEQNKQLELEIEKLYGSLQMKQMEN 2370
            LA++      + + L  L ++ +  KN+++      ++   L+ ++++    L     E 
Sbjct: 1449 LAVAKDNLMGMETRLSNLKKENDDMKNKIITLEDSIQEVDDLKRQLKEAKKELDKPSPEL 1508

Query: 2369 TLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNS 2190
              LK  N+K+ D       +S  ++   + +     N++ ELA  KE   +  +      
Sbjct: 1509 DTLKSTNKKLQDDLDNARNESLNLKNDLDNLQNDYNNLQTELADVKEERDTFRERAAALE 1568

Query: 2189 DAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAE 2010
                +V    E L+   + + +  ++  G  N L  + + ++    ++QD      +E E
Sbjct: 1569 KDLVRVKRENEELVEQNETLRTELDDCRGENNRLLKELEKLKSENVKLQDNLINARSEGE 1628

Query: 2009 IRAQEVLRLQAEVDAIQHILIELK-----RKNQTLQDESQRNAKELWNAKAR--LNNVMS 1851
               +++ +L+ +   ++  L + +     RK + ++ + + +  +  NAK +  L +   
Sbjct: 1629 RLKEDLNKLKKDYSDLRTDLTKAREDRDVRKEKDMELDKEIDELKAVNAKLKSDLYDCQK 1688

Query: 1850 KNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLE 1677
            +N  L  Q   LKAE + + +KA     ++   E + ++L    E +++     K+ E
Sbjct: 1689 ENEKLRKQVTKLKAE-NDKLKKALDKDLDQKETEIDKDILDDCNEYVEANKILRKNFE 1745


>ref|XP_006560776.1| PREDICTED: sporulation-specific protein 15 isoform X1 [Apis
            mellifera]
          Length = 2064

 Score =  133 bits (334), Expect = 6e-28
 Identities = 190/894 (21%), Positives = 380/894 (42%), Gaps = 32/894 (3%)
 Frame = -3

Query: 3143 EESCKHLTEALE--NHIYGSLLESCVVDREAHIKQLMEQMNALVKEKRELENDAQRGEEI 2970
            E++  +LT+ LE  N+   +L +   +++ A +K L EQ+  +   K++L+   ++  ++
Sbjct: 259  EQTVANLTKELEEKNNKIDALKKE--LEQMAILKSLEEQIAIM---KQDLKKKDEKISDL 313

Query: 2969 SQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEA-NNNLLEQKDNI 2793
              +L+     L  +  L  + +    EL E    LR+  E+I  ++    + L E+ D I
Sbjct: 314  LNTLRQSEINLLGLEGLKSKLEHLEPELYE----LRESKEEIMEELNMMRDTLKERNDQI 369

Query: 2792 IVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMA 2613
            I  L  K +  E  +S ++     +++  ++S  E E+L  +L    +D     + L   
Sbjct: 370  IQILEDKAKLEEYYKSKVETLEAKLDEQASLS-AELEDLRNEL----EDQRAKNKELEAC 424

Query: 2612 VDDRAFMEKQLQDLENQKETVSKELALS---VSREQKLASDLKALSEKEESTKNQLLIQT 2442
              D   +EK+L +LE ++  + KEL  +   + R QK   DLK + E E + K++L    
Sbjct: 425  CKDMDALEKKLSELEKKRSELEKELEDNRGELERLQKENLDLKDVIEVERAEKDKLRDLL 484

Query: 2441 EQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDI 2262
            E++K+L+ + E L+  L+  + EN  L    + + DL K L   +  ++     +  +  
Sbjct: 485  EESKKLKEDNENLWAQLERLRGENDDLMGQKKALEDLNKQLNEDNESMKRTMGNLEARID 544

Query: 2261 NIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRN 2082
            ++ +EL+  +    +  D  +        V   LE  L   +++ +  ++    ++ L+ 
Sbjct: 545  SLSNELSNVERERDALLDENE-------SVKRELERTLTENENLKTELDKADEQLDKLKT 597

Query: 2081 DAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQR 1902
            +   +Q   + M+        E E   + V  L+ +++  +  + E+K     L+D+ + 
Sbjct: 598  ERNELQRNFDTMK-------LENETLKENVKALKDDLEESKREVDEMKAVGDALKDKEEL 650

Query: 1901 NAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSE 1722
               E    +  + N+ ++N  L+ +N  L+        K   +++E + VESE+  L ++
Sbjct: 651  KDAEFRELQQNMQNLKTENGELKKENDDLRTRSSELEHKLDNVKKELDKVESENADLRAK 710

Query: 1721 VENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNE 1542
            ++NL+ EL++ K               + +E   L+I S + A +K    +DE+  L+ E
Sbjct: 711  IDNLEKELEKDK---------------KEIEQLKLEISSLKDALDK---CVDEMEKLKVE 752

Query: 1541 NAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLK 1362
            N KLK E +     +  +NV                 N +A   E +           L 
Sbjct: 753  NEKLKKEGMKVEATWLEENV-----------------NLKAKNTELEEN---------LA 786

Query: 1361 NKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRS 1182
            N    L+   +  SE A++    +R  Q++ +  +E+ Q  S++             +  
Sbjct: 787  NTVNELD---KMRSENADLLSELNRLKQELESGRKEIDQLKSEIGSMKDALGKCVDEIEK 843

Query: 1181 LKKENTRLRSEMKGELTPSRSFKHREGSFIK----EINIGDEDDTPLIQXXXXXXXXXXX 1014
            LK EN  L+SE++G L   R     E + +K    E+     D +  +            
Sbjct: 844  LKTENKDLKSEVQG-LESERDRLTNEVADLKPKISELQEKLTDASKKLDEAKTEDSDLRA 902

Query: 1013 KIDTRTSETQ----EIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXX 846
            ++D    E +    EID L  +     N ++   ++ + L N   EL+            
Sbjct: 903  EVDRLKKELESAGKEIDQLKAEMNSLKNGLNKCVEEMEKLTNENSELKSQVHGLRGEGDS 962

Query: 845  XXXKWGGI-DMNS--------IEKQLKE-------LNIHVMQLVEHNTRLKKDVKFGFAW 714
               +   + D NS        + KQL E       L     +L   NT++KK+++     
Sbjct: 963  LASELTNVKDENSALKDEKDQLNKQLAENKTENERLKKQNDELESENTKIKKELESCKNE 1022

Query: 713  ANSMHDLNG--QEQKLKVDEEVPILCHQNSKIAERLDINTDKARALDMEVQRIR 558
             N++ + N   +E+  K+ E++  L  + +K+   L    DK + L+ ++ R R
Sbjct: 1023 NNNLKEENNKLKEELEKLGEQLKSLNDETNKLRRELKEAEDKIQILEPQLSRAR 1076



 Score =  121 bits (304), Expect = 2e-24
 Identities = 203/985 (20%), Positives = 405/985 (41%), Gaps = 87/985 (8%)
 Frame = -3

Query: 3215 KILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLME 3036
            K +++   L+ +  +L+++V   E E  +   E  +     S L+  + D    + +   
Sbjct: 836  KCVDEIEKLKTENKDLKSEVQGLESERDRLTNEVADLKPKISELQEKLTDASKKLDEAKT 895

Query: 3035 QMNALVKE----KRELENDAQRGEEISQSLKDEVFQLKE-VSRLYEEEKQHT---IELQE 2880
            + + L  E    K+ELE+    G+EI Q LK E+  LK  +++  EE ++ T    EL+ 
Sbjct: 896  EDSDLRAEVDRLKKELES---AGKEIDQ-LKAEMNSLKNGLNKCVEEMEKLTNENSELKS 951

Query: 2879 NFNALRQKNEDICLKI----EANNNLLEQKDNIIVELSHKLQENE--------------- 2757
              + LR + + +  ++    + N+ L ++KD +  +L+    ENE               
Sbjct: 952  QVHGLRGEGDSLASELTNVKDENSALKDEKDQLNKQLAENKTENERLKKQNDELESENTK 1011

Query: 2756 --EQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQ 2583
              ++  + +N+  ++++ +   + E E+L  QL  L D+ N L+  L  A D    +E Q
Sbjct: 1012 IKKELESCKNENNNLKEENNKLKEELEKLGEQLKSLNDETNKLRRELKEAEDKIQILEPQ 1071

Query: 2582 LQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKL 2403
            L    ++ E    ELA+  +   +L   L        + +N L I  +Q   L  +++  
Sbjct: 1072 LSRARSENEKSQNELAVLRNEANELKVKLDREMLDNTNMRNALKILEDQVLDLNKKLDNC 1131

Query: 2402 YGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIED---ELA-RT 2235
                   + EN   KD   K+ D  +++     E    +E I      IE    ++A + 
Sbjct: 1132 REENDALKEEN---KDLKTKLSDTGQVVLNLKTECDNLKEDIASLQKTIEQLKQKIADQE 1188

Query: 2234 KEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVAL 2055
             E+     +  K   D   K+   LE +L   ++    K+ +  ++  L+N+   +   +
Sbjct: 1189 AEIDHWKVEHCKFELD-NEKLKADLEKVLKDLNECQIAKKAIESDLIKLKNEKDDLNKNM 1247

Query: 2054 ----EQMQDTKSELFAEAEIRAQ---EVLRLQAEVDAIQHILIELKRKNQTLQDESQRNA 1896
                 Q+   K  L AE   + +   ++  L +E++A++  L +L+  N   + E     
Sbjct: 1248 TDLTSQLDRQKRSLEAEKSAKDRGDVQIASLNSELEALKKELEKLRADNSKYKSEIDDLG 1307

Query: 1895 KELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVE 1716
            K+L +AK  LN+   + + L++ N +L++EL           +    ++ +++ L++E++
Sbjct: 1308 KQLASAKNELNDCREEIVVLKNANSALRSEL-----------DPLRSLKDDYSRLTTELD 1356

Query: 1715 NLKSE----LKESKDLEGYFLRLFEILLGQHVEVASL----------------DIESCRF 1596
             LKSE    L++ + LE  F +L     GQ VE+  L                D++SC+ 
Sbjct: 1357 GLKSENTKLLQDKRSLEDEFGKLRGEGDGQRVEIDRLRTTLDAEKTAAEKLKSDLQSCKD 1416

Query: 1595 AEEKLMRILDE----LICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVL------- 1449
              +KL   ++E    L  +  EN +LK E      D  RK +    A+  S+        
Sbjct: 1417 ENDKLQTQINEMKRSLDKMGTENDRLKREV-----DESRKKLEDMEAKVKSLENQLSNLS 1471

Query: 1448 -----ISKSLGNGRANQREFQNKEEDSSGV-DLLKNKCTRLEFQVQKLSEKAEMFETKSR 1287
                 + K L   R +    +N+ E  +GV D ++ + T L+ +++ L E+      ++ 
Sbjct: 1472 AEKEELVKELYRTREDLNNLRNELEKQTGVKDTMEKESTNLKEELKALKEELNKTRDEND 1531

Query: 1286 EAQQMANKLE-EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK-------GELT 1131
              +   +KL  E+ +    +             + +L + N  L  E+        G  T
Sbjct: 1532 RLKNENDKLNAEIARLNKQLDALKDESANLKNDIENLNERNAELSKELAVAKDNLMGMET 1591

Query: 1130 PSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRK 951
               + K +E   +K   I  ED    +            ++D     + E+DTL   N+K
Sbjct: 1592 RLSNLK-KENDDMKNKIITLEDSIQEVDDLKRQLKEAKKELD---KPSPELDTLKSTNKK 1647

Query: 950  YWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMN--SIEKQLKELNIH 777
              + + +   ++ +L+N +  LQ               +         ++EK L  +   
Sbjct: 1648 LQDDLDNARNESLNLKNDLDNLQNDYNNLQTELADVKEERDTFRERAAALEKDLVRVKRE 1707

Query: 776  VMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEEVPILCHQNSKIAERLDINTD 597
              +LVE N  L+ +          + D  G+  +L   +E+  L  +N K+ + L     
Sbjct: 1708 NEELVEQNETLRTE----------LDDCRGENNRLL--KELEKLKSENVKLQDNLINARS 1755

Query: 596  KARALDMEVQRIRLILSRIPTKPTE 522
            +   L  ++ +++   S + T  T+
Sbjct: 1756 EGERLKEDLNKLKKDYSDLRTDLTK 1780



 Score =  112 bits (280), Expect = 1e-21
 Identities = 189/949 (19%), Positives = 388/949 (40%), Gaps = 60/949 (6%)
 Frame = -3

Query: 3227 AQHQKILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYG-----SLLESCVVDR 3063
            A+ +++ ++   L+ + GEL+     +E +  +  +  LE+ +         +ES   D 
Sbjct: 653  AEFRELQQNMQNLKTENGELK-----KENDDLRTRSSELEHKLDNVKKELDKVESENADL 707

Query: 3062 EAHIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEE--KQHTIE 2889
             A I  L +++    KE  +L+ +    ++      DE+ +LK  +   ++E  K     
Sbjct: 708  RAKIDNLEKELEKDKKEIEQLKLEISSLKDALDKCVDEMEKLKVENEKLKKEGMKVEATW 767

Query: 2888 LQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQM 2709
            L+EN N L+ KN +          L E   N + EL     EN +  S L    Q +E  
Sbjct: 768  LEENVN-LKAKNTE----------LEENLANTVNELDKMRSENADLLSELNRLKQELE-- 814

Query: 2708 HAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDD-------RAFMEKQLQDLENQKETV 2550
                 + R+E+++    L+ ++  +K+AL   VD+          ++ ++Q LE++++ +
Sbjct: 815  -----SGRKEIDQ----LKSEIGSMKDALGKCVDEIEKLKTENKDLKSEVQGLESERDRL 865

Query: 2549 SKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMEN 2370
            + E+A    +  +L   L   S+K +  K +      +  +L+ E+E     +   + E 
Sbjct: 866  TNEVADLKPKISELQEKLTDASKKLDEAKTEDSDLRAEVDRLKKELESAGKEIDQLKAEM 925

Query: 2369 TLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNS 2190
              LK+G  K  +  + L  ++ E++ Q  G+  +  ++  EL   K+   +  D K   +
Sbjct: 926  NSLKNGLNKCVEEMEKLTNENSELKSQVHGLRGEGDSLASELTNVKDENSALKDEKDQLN 985

Query: 2189 DAGAKVSGILEMLLPMKDDVFS----LKEEV---LGNINSLRNDAQMVQVALEQMQDTKS 2031
               A+     E L    D++ S    +K+E+       N+L+ +   ++  LE++ +   
Sbjct: 986  KQLAENKTENERLKKQNDELESENTKIKKELESCKNENNNLKEENNKLKEELEKLGEQLK 1045

Query: 2030 ELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMS 1851
             L  E     +E+   + ++  ++  L   + +N+  Q+E      E    K +L+  M 
Sbjct: 1046 SLNDETNKLRRELKEAEDKIQILEPQLSRARSENEKSQNELAVLRNEANELKVKLDREML 1105

Query: 1850 KNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSE-------VENLKSELKE 1692
             N N+ +  + L+ ++    +K    +EE + ++ E+  L ++       V NLK+E   
Sbjct: 1106 DNTNMRNALKILEDQVLDLNKKLDNCREENDALKEENKDLKTKLSDTGQVVLNLKTECDN 1165

Query: 1691 SKD----LEGYFLRLFEILLGQHVEVASLDIESCRFA--EEKLMRILDELICLRNENAKL 1530
             K+    L+    +L + +  Q  E+    +E C+F    EKL   L++++   NE  ++
Sbjct: 1166 LKEDIASLQKTIEQLKQKIADQEAEIDHWKVEHCKFELDNEKLKADLEKVLKDLNE-CQI 1224

Query: 1529 KNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCT 1350
              +A+ E    + KN      + M+ L S+     R+ + E   K+     +  L ++  
Sbjct: 1225 AKKAI-ESDLIKLKNEKDDLNKNMTDLTSQLDRQKRSLEAEKSAKDRGDVQIASLNSELE 1283

Query: 1349 RLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKE 1170
             L+ +++KL  +A+  + KS E   +  +L   +  L+D              +  LK  
Sbjct: 1284 ALKKELEKL--RADNSKYKS-EIDDLGKQLASAKNELND----------CREEIVVLKNA 1330

Query: 1169 NTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSE 990
            N+ LRS    EL P RS K        E++    ++T L+Q                  +
Sbjct: 1331 NSALRS----ELDPLRSLKDDYSRLTTELDGLKSENTKLLQDKRSLEDEFGKLRGEGDGQ 1386

Query: 989  TQEIDTL---------------------MDDNRKYWNRVSHFTKQTQSLQNSVQELQQXX 873
              EID L                      D+N K   +++   +    +      L++  
Sbjct: 1387 RVEIDRLRTTLDAEKTAAEKLKSDLQSCKDENDKLQTQINEMKRSLDKMGTENDRLKREV 1446

Query: 872  XXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDL 693
                              + S+E QL  L+    +LV+   R ++D+       N +   
Sbjct: 1447 DESRKKLEDME-----AKVKSLENQLSNLSAEKEELVKELYRTREDLN---NLRNELEKQ 1498

Query: 692  NG-----QEQKLKVDEEVPILCHQNSKIAERLDINTDKARALDMEVQRI 561
             G     +++   + EE+  L  + +K  +  D   ++   L+ E+ R+
Sbjct: 1499 TGVKDTMEKESTNLKEELKALKEELNKTRDENDRLKNENDKLNAEIARL 1547



 Score =  109 bits (273), Expect = 7e-21
 Identities = 127/615 (20%), Positives = 285/615 (46%), Gaps = 12/615 (1%)
 Frame = -3

Query: 3044 LMEQMNALVKEKRELEND--AQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFN 2871
            L  +   L+++KR LE++    RGE   Q +     ++  +    + EK    +L+ +  
Sbjct: 1358 LKSENTKLLQDKRSLEDEFGKLRGEGDGQRV-----EIDRLRTTLDAEKTAAEKLKSDLQ 1412

Query: 2870 ALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQT 2691
            + + +N+ +  +I      L++       L  ++ E+ ++   ++  ++S+E   +    
Sbjct: 1413 SCKDENDKLQTQINEMKRSLDKMGTENDRLKREVDESRKKLEDMEAKVKSLENQLSNLSA 1472

Query: 2690 EREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQK 2511
            E+EEL ++L   R+D+N+L+  L          EKQ       K+T+ KE          
Sbjct: 1473 EKEELVKELYRTREDLNNLRNEL----------EKQ----TGVKDTMEKE-------STN 1511

Query: 2510 LASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDG----NEK 2343
            L  +LKAL E+   T+++      +N +L  EI +L   L   + E+  LK+     NE+
Sbjct: 1512 LKEELKALKEELNKTRDENDRLKNENDKLNAEIARLNKQLDALKDESANLKNDIENLNER 1571

Query: 2342 IYDLCKLLATKSREVQGQQ---EGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKV 2172
              +L K LA     + G +     + K++ ++++++   ++  +   D+K+   +A  + 
Sbjct: 1572 NAELSKELAVAKDNLMGMETRLSNLKKENDDMKNKIITLEDSIQEVDDLKRQLKEAKKE- 1630

Query: 2171 SGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEV 1992
               L+   P  D + S  +++  ++++ RN++  ++  L+ +Q+  + L  E     +E 
Sbjct: 1631 ---LDKPSPELDTLKSTNKKLQDDLDNARNESLNLKNDLDNLQNDYNNLQTELADVKEER 1687

Query: 1991 LRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLK 1812
               +    A++  L+ +KR+N+ L ++++    EL + +   N ++ +   L+S+N  L+
Sbjct: 1688 DTFRERAAALEKDLVRVKRENEELVEQNETLRTELDDCRGENNRLLKELEKLKSENVKLQ 1747

Query: 1811 AELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHV 1632
              L     +  +++E+ N ++ +++ L +++   + +    K+ +    +  + L   + 
Sbjct: 1748 DNLINARSEGERLKEDLNKLKKDYSDLRTDLTKAREDRDVRKEKDMELDKEIDELKAVNA 1807

Query: 1631 EVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSV 1452
            ++ S D+  C+   EKL +   ++  L+ EN KLK +AL +  D +   +     +  + 
Sbjct: 1808 KLKS-DLYDCQKENEKLRK---QVTKLKAENDKLK-KALDKDLDQKETEIDKDILDDCNE 1862

Query: 1451 LISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQ--VQKLSEKAEMFETKSR-EA 1281
             +        AN+   +N E    GV  L++    L+ +    K+++K E  E  +   A
Sbjct: 1863 YV-------EANKILRKNFENQLKGVQRLRDYINYLDGKGTEPKMADKLEESEMNNPVNA 1915

Query: 1280 QQMANKLEEMQQTLS 1236
            ++    L +M Q LS
Sbjct: 1916 KKDIEDLLKMSQDLS 1930



 Score = 76.3 bits (186), Expect = 8e-11
 Identities = 101/538 (18%), Positives = 229/538 (42%), Gaps = 21/538 (3%)
 Frame = -3

Query: 3227 AQHQKILEDYYALQKKAGELQTKVHIREEESCKHLT----EALENHIYGSLLESCVVDRE 3060
            +++ K+L+D  +L+ + G+L+ +   +  E  +  T    E        S L+SC  + +
Sbjct: 1360 SENTKLLQDKRSLEDEFGKLRGEGDGQRVEIDRLRTTLDAEKTAAEKLKSDLQSCKDEND 1419

Query: 3059 AHIKQLMEQMNALVKE-------KRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQ 2901
                Q+ E   +L K        KRE++   ++ E++   +K    QL  +S   EE  +
Sbjct: 1420 KLQTQINEMKRSLDKMGTENDRLKREVDESRKKLEDMEAKVKSLENQLSNLSAEKEELVK 1479

Query: 2900 HTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQS 2721
                 +E+ N LR +       +E    + +  +     L  +L+  +E+ +  +++   
Sbjct: 1480 ELYRTREDLNNLRNE-------LEKQTGVKDTMEKESTNLKEELKALKEELNKTRDENDR 1532

Query: 2720 VEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKE 2541
            ++  +     E   LN+QL  L+D+  +LK                +++L  +   +SKE
Sbjct: 1533 LKNENDKLNAEIARLNKQLDALKDESANLK--------------NDIENLNERNAELSKE 1578

Query: 2540 LALSVSREQKLASDLKALSEKEESTKNQLLI---QTEQNKQLELEIEKLYGSLQMKQMEN 2370
            LA++      + + L  L ++ +  KN+++      ++   L+ ++++    L     E 
Sbjct: 1579 LAVAKDNLMGMETRLSNLKKENDDMKNKIITLEDSIQEVDDLKRQLKEAKKELDKPSPEL 1638

Query: 2369 TLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNS 2190
              LK  N+K+ D       +S  ++   + +     N++ ELA  KE   +  +      
Sbjct: 1639 DTLKSTNKKLQDDLDNARNESLNLKNDLDNLQNDYNNLQTELADVKEERDTFRERAAALE 1698

Query: 2189 DAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAE 2010
                +V    E L+   + + +  ++  G  N L  + + ++    ++QD      +E E
Sbjct: 1699 KDLVRVKRENEELVEQNETLRTELDDCRGENNRLLKELEKLKSENVKLQDNLINARSEGE 1758

Query: 2009 IRAQEVLRLQAEVDAIQHILIELK-----RKNQTLQDESQRNAKELWNAKAR--LNNVMS 1851
               +++ +L+ +   ++  L + +     RK + ++ + + +  +  NAK +  L +   
Sbjct: 1759 RLKEDLNKLKKDYSDLRTDLTKAREDRDVRKEKDMELDKEIDELKAVNAKLKSDLYDCQK 1818

Query: 1850 KNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLE 1677
            +N  L  Q   LKAE + + +KA     ++   E + ++L    E +++     K+ E
Sbjct: 1819 ENEKLRKQVTKLKAE-NDKLKKALDKDLDQKETEIDKDILDDCNEYVEANKILRKNFE 1875


>ref|XP_001739846.1| intracellular protein transport protein USO1 [Entamoeba dispar
            SAW760] gi|165896309|gb|EDR23762.1| intracellular protein
            transport protein USO1, putative [Entamoeba dispar
            SAW760]
          Length = 1080

 Score =  130 bits (327), Expect = 4e-27
 Identities = 170/773 (21%), Positives = 340/773 (43%), Gaps = 91/773 (11%)
 Frame = -3

Query: 3188 QKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNALVKEK 3009
            +++  EL+ +V   EEE  K +TE L N   G             I +L  ++  + KEK
Sbjct: 292  EERENELKEQVKKVEEEKSKLITE-LSNGNDG-------------ISKLNGELTQIKKEK 337

Query: 3008 RELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIE 2829
             E++ + +  +E  +  ++E+ ++KE  +  EEEK  +IE +     L+Q+ E+    +E
Sbjct: 338  EEIKKELEEEKEKLERKEEELKEIKEAKQQLEEEKIKSIEEK---TTLQQELEEKNKLVE 394

Query: 2828 ANNNLLEQKDNIIVELSHKLQEN---EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVL 2658
              N + ++K+++  ELS   +E    EE+++ + N+ + +++ +  S    EE  +++  
Sbjct: 395  EINEIKKEKEDVTNELSAVKEEKNKIEEEKNKITNENKEIKEENIKS---IEEKTQEINS 451

Query: 2657 LRDDVNHLKEALSMAVDDRAFMEK-------QLQDLENQKETVSKELALSVSR------- 2520
            L   +  LK  L ++  +R  +EK       +L D++ Q E + K++  + +R       
Sbjct: 452  LTTSIEELKNYLEVSKGERIEVEKERDRATSELNDIKLQNEGLKKQVEETQNRMAEMQKS 511

Query: 2519 ----EQKLASDLK----ALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTL 2364
                E ++ S L      L+EKE+    Q++    Q  Q  + +E++   L   Q + T 
Sbjct: 512  FEGSENEMISSLNNQITQLNEKEKQMNEQVMALQTQLSQSNISLEEVKKDLIESQNKYTQ 571

Query: 2363 L---KDG--------NEKIYDLCKLLATKSRE---VQGQQEGILKQDINIEDEL------ 2244
            +   KDG        NE+   + + L    +E   +Q +Q+  + +  NI ++L      
Sbjct: 572  VIEEKDGIEHERNKINEEYKTINEELEKNKKELNDLQIKQDNKIIELNNIINDLKEERTN 631

Query: 2243 --ARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQM 2070
               + K+V    T +    S+    +S + E L+ +K +    KEE+   +N+++ + + 
Sbjct: 632  FEEQVKKVEEEKTKLITELSNGNDGISKLNEELMQIKKE----KEEISNELNAVKEEKKQ 687

Query: 2069 VQ-----------VALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAI-----------QH 1956
            ++              E++++ K+EL  E E   +    LQ E++ I           + 
Sbjct: 688  IEEEKEKEKTEIKEEKEKIEEEKNELIKEIEKEKEGKKELQIEINKINTQMKEIEENKKQ 747

Query: 1955 ILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQ 1776
            I+ +  ++ + L++ES+   KEL   K   + +MS   +       L  E+    ++   
Sbjct: 748  IIFDNNKEIERLKEESENIQKELNQIKEEKSKLMSDLSSGSDGLSKLNEEIETINKEKEG 807

Query: 1775 IQEERNVVESEHNVLSSEVENLKSE---LKESKDLEGYFLRLFEILLGQHVEVASLDIES 1605
            IQ E N ++ E+N +  E+E    E   LKE K+     L      + Q  E  +     
Sbjct: 808  IQNEFNQLKEENNKIQEELEQKNQELIKLKEEKEKLSLDLTNGNDGINQLNENLNQIKND 867

Query: 1604 CRFAEEKLMRILDELICLRNENAKLKN----------------EALYEYHDYERKNVSGS 1473
                 EK +++ +E+  L++EN +L N                 A+ E  D   K +   
Sbjct: 868  KEELTEKNIQLQNEINKLKSENEELTNNISIEKEGLKQVNEEVNAIKEERDELVKQIRNI 927

Query: 1472 RAEAMSVLISKSLGNGRANQREFQ---NKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMF 1302
              E   V    +L     N+R  Q    KEE S   + LKN    L+ +++++ ++ E  
Sbjct: 928  EEEKRKVEEELNLNGSELNERIIQISNEKEEVSQECNELKNSLKELQNKIEEIEQEKEGN 987

Query: 1301 ETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK 1143
            E   +E      ++EE+Q+ +++              +++LK+E  R++ E++
Sbjct: 988  EISKKE------QIEELQEEINERDND----------IKNLKEEIERIQKEVQ 1024



 Score =  122 bits (307), Expect = 8e-25
 Identities = 139/658 (21%), Positives = 301/658 (45%), Gaps = 24/658 (3%)
 Frame = -3

Query: 3146 EEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNALVKEKRELENDAQRGEEIS 2967
            + E  K   E  +N +   + +S        I  L  Q+  L ++++++         + 
Sbjct: 490  QNEGLKKQVEETQNRM-AEMQKSFEGSENEMISSLNNQITQLNEKEKQMNEQVMA---LQ 545

Query: 2966 QSLKDEVFQLKEVSR-LYEEEKQHTIELQENF------NALRQKNEDICLKIEAN----N 2820
              L      L+EV + L E + ++T  ++E        N + ++ + I  ++E N    N
Sbjct: 546  TQLSQSNISLEEVKKDLIESQNKYTQVIEEKDGIEHERNKINEEYKTINEELEKNKKELN 605

Query: 2819 NLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVN 2640
            +L  ++DN I+EL++ + + +E+R+  +  ++ VE+       E+ +L  +L    D ++
Sbjct: 606  DLQIKQDNKIIELNNIINDLKEERTNFEEQVKKVEE-------EKTKLITELSNGNDGIS 658

Query: 2639 HLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKN 2460
             L E L         ++K+ +++ N+   V +E       ++K  +++K   EK E  KN
Sbjct: 659  KLNEELMQ-------IKKEKEEISNELNAVKEEKKQIEEEKEKEKTEIKEEKEKIEEEKN 711

Query: 2459 QLLIQTEQ----NKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQG 2292
            +L+ + E+     K+L++EI K+  + QMK++E       N+K     +++   ++E+  
Sbjct: 712  ELIKEIEKEKEGKKELQIEINKI--NTQMKEIEE------NKK-----QIIFDNNKEI-- 756

Query: 2291 QQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEE 2112
              E + ++  NI+ EL + KE      +  K+ SD  +   G+ +           L EE
Sbjct: 757  --ERLKEESENIQKELNQIKE------EKSKLMSDLSSGSDGLSK-----------LNEE 797

Query: 2111 VLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIE---- 1944
                I ++  + + +Q    Q+++  +++  E E + QE+++L+ E + +   L      
Sbjct: 798  ----IETINKEKEGIQNEFNQLKEENNKIQEELEQKNQELIKLKEEKEKLSLDLTNGNDG 853

Query: 1943 LKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEE 1764
            + + N+ L ++ + + +EL     +L N ++K   L+S+N  L   + ++ +   Q+ EE
Sbjct: 854  INQLNENL-NQIKNDKEELTEKNIQLQNEINK---LKSENEELTNNISIEKEGLKQVNEE 909

Query: 1763 RNVVESEHNVLSSEVENLKSE---LKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFA 1593
             N ++ E + L  ++ N++ E   ++E  +L G  L    I +    E  S +    + +
Sbjct: 910  VNAIKEERDELVKQIRNIEEEKRKVEEELNLNGSELNERIIQISNEKEEVSQECNELKNS 969

Query: 1592 EEKLMRILDELICLRNENAKLKNEALYEYHD--YERKNVSGSRAEAMSVLISKSLGNGRA 1419
             ++L   ++E+   +  N   K E + E  +   ER N   +  E +  +          
Sbjct: 970  LKELQNKIEEIEQEKEGNEISKKEQIEELQEEINERDNDIKNLKEEIERI---------- 1019

Query: 1418 NQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQ 1245
             Q+E Q KEED   +   +     +E    +L E   + E + +E + ++N+ EE ++
Sbjct: 1020 -QKEVQEKEEDKEQISTTE----EVEELKNELIETQRLLEEERKEKESISNEFEETKE 1072



 Score =  117 bits (292), Expect = 4e-23
 Identities = 161/932 (17%), Positives = 386/932 (41%), Gaps = 78/932 (8%)
 Frame = -3

Query: 3119 EALENHIYGSLLESCVVDREAHIKQLMEQMNALVKEKRELENDAQRGE-------EISQS 2961
            E ++N +    +ES    +E  + ++ E+   +  EK +L  D   G        E+   
Sbjct: 4    ENIQNELNQIKIESS--QKEEELNKIKEEKQQVEDEKAKLITDIANGNDGLTKLNEVIDK 61

Query: 2960 LKDEVFQLK-EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLL-------EQ 2805
            LKDE   +  E++++  E    T E  +    ++QK  +I    E  + L+       E+
Sbjct: 62   LKDEKENISNELNQIKNERDNITNEFNKTKEEIQQKENEITQLHEEKSGLVNELSRIKEE 121

Query: 2804 KDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEA 2625
            K  I  E     QE E + + L  D   VE      +TE++E+  +L  ++++   ++E 
Sbjct: 122  KQKIEDEKIFIQQEKENEITKLNEDKIGVENELNQIKTEKQEIENELNQIKEEKQKIEEE 181

Query: 2624 LSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQ 2445
             S  + + +     +  L  +   + KE  +++    ++ ++  +  E+    +N L   
Sbjct: 182  KSNLITELSNGNDGISKLNEELMQIKKEKEITLDELNQIKNEFTSFKEQNIQKENDL--- 238

Query: 2444 TEQNKQLELEIEKLYGSLQMKQME----NTLLKDGNEKIYDLCKLLATKSREVQGQQEGI 2277
             ++N +++ E+E+    +   + E       L +  +++ +  + + T + E + ++  +
Sbjct: 239  KDENNKIQQELEQKNNEISKLEEEKGNITNELSNTKQELEEKKEEITTITHEKEERENEL 298

Query: 2276 LKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNI 2097
             +Q   +E+E ++        T++   N D  +K++G L  +   K+++    EE    +
Sbjct: 299  KEQVKKVEEEKSKL------ITELSNGN-DGISKLNGELTQIKKEKEEIKKELEEEKEKL 351

Query: 2096 NSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQ----------EVLRLQAEVDAIQHILI 1947
                 + + ++ A +Q+++ K +   E     Q          E+  ++ E + + + L 
Sbjct: 352  ERKEEELKEIKEAKQQLEEEKIKSIEEKTTLQQELEEKNKLVEEINEIKKEKEDVTNELS 411

Query: 1946 ELKRKNQTLQDESQRNAKELWNAKARLNNVMS-----KNIN-LESQNRSLKAELHLQAQK 1785
             +K +   +++E  +   E  N + +  N+ S     + IN L +    LK  L +   +
Sbjct: 412  AVKEEKNKIEEEKNKITNE--NKEIKEENIKSIEEKTQEINSLTTSIEELKNYLEVSKGE 469

Query: 1784 AFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIES 1605
              ++++ER+   SE N +  + E LK +++E+++      + FE   G   E+ S     
Sbjct: 470  RIEVEKERDRATSELNDIKLQNEGLKKQVEETQNRMAEMQKSFE---GSENEMISSLNNQ 526

Query: 1604 CRFAEEKLMRILDELICLRNENA-------KLKNEALYEYHDY-----ERKNVSGSRAEA 1461
                 EK  ++ ++++ L+ + +       ++K + +   + Y     E+  +   R + 
Sbjct: 527  ITQLNEKEKQMNEQVMALQTQLSQSNISLEEVKKDLIESQNKYTQVIEEKDGIEHERNKI 586

Query: 1460 MS--VLISKSLGNGRANQREFQNKEED-----SSGVDLLKNKCTRLEFQVQKLSEKAEMF 1302
                  I++ L   +    + Q K+++     ++ ++ LK + T  E QV+K+ E+    
Sbjct: 587  NEEYKTINEELEKNKKELNDLQIKQDNKIIELNNIINDLKEERTNFEEQVKKVEEEKTKL 646

Query: 1301 ETKSREAQQMANKL-EEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPS 1125
             T+        +KL EE+ Q   +               + +++E  + ++E+K E    
Sbjct: 647  ITELSNGNDGISKLNEELMQIKKEKEEISNELNAVKEEKKQIEEEKEKEKTEIKEE---K 703

Query: 1124 RSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSE-----TQEIDTLMDD 960
               +  +   IKEI   +++    +Q           +I+    +      +EI+ L ++
Sbjct: 704  EKIEEEKNELIKEIE-KEKEGKKELQIEINKINTQMKEIEENKKQIIFDNNKEIERLKEE 762

Query: 959  NRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGI---------DMNSI 807
            +      ++   ++   L + +                   +  GI         + N I
Sbjct: 763  SENIQKELNQIKEEKSKLMSDLSSGSDGLSKLNEEIETINKEKEGIQNEFNQLKEENNKI 822

Query: 806  EKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQ---------EQKLKVDEEV 654
            +++L++ N  +++L E   +L  D+  G    N +++   Q         E+ +++  E+
Sbjct: 823  QEELEQKNQELIKLKEEKEKLSLDLTNGNDGINQLNENLNQIKNDKEELTEKNIQLQNEI 882

Query: 653  PILCHQNSKIAERLDINTDKARALDMEVQRIR 558
              L  +N ++   + I  +  + ++ EV  I+
Sbjct: 883  NKLKSENEELTNNISIEKEGLKQVNEEVNAIK 914



 Score =  104 bits (260), Expect = 2e-19
 Identities = 108/504 (21%), Positives = 238/504 (47%), Gaps = 6/504 (1%)
 Frame = -3

Query: 3191 LQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNALVKE 3012
            L+++    + +V   EEE  K +TE    +   S L   ++  +   +++  ++NA+ +E
Sbjct: 625  LKEERTNFEEQVKKVEEEKTKLITELSNGNDGISKLNEELMQIKKEKEEISNELNAVKEE 684

Query: 3011 KRELENDAQRGEEISQSLKDEVFQ-----LKEVSRLYEEEKQHTIELQENFNALRQKNED 2847
            K+++E + ++ +   +  K+++ +     +KE+ +  E +K+  IE+ +    +++  E+
Sbjct: 685  KKQIEEEKEKEKTEIKEEKEKIEEEKNELIKEIEKEKEGKKELQIEINKINTQMKEIEEN 744

Query: 2846 ICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQ 2667
                I  NN  +E+       +  +L + +E++S L +D+ S     +    E E +N++
Sbjct: 745  KKQIIFDNNKEIERLKEESENIQKELNQIKEEKSKLMSDLSSGSDGLSKLNEEIETINKE 804

Query: 2666 LVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKAL 2487
               ++++ N LKE  +   ++     ++L  L+ +KE +S +L        +L  +L  +
Sbjct: 805  KEGIQNEFNQLKEENNKIQEELEQKNQELIKLKEEKEKLSLDLTNGNDGINQLNENLNQI 864

Query: 2486 -SEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATK 2310
             ++KEE T+  + +Q E NK L+ E E+L  ++    +E   LK  NE++          
Sbjct: 865  KNDKEELTEKNIQLQNEINK-LKSENEELTNNI---SIEKEGLKQVNEEV---------- 910

Query: 2309 SREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDV 2130
               ++ +++ ++KQ  NIE+E              +KV  +     S + E ++ + ++ 
Sbjct: 911  -NAIKEERDELVKQIRNIEEE-------------KRKVEEELNLNGSELNERIIQISNE- 955

Query: 2129 FSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHIL 1950
               KEEV    N L+N  + +Q  +E+++  K         + +++  LQ E++   + +
Sbjct: 956  ---KEEVSQECNELKNSLKELQNKIEEIEQEKE---GNEISKKEQIEELQEEINERDNDI 1009

Query: 1949 IELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQ 1770
              LK + + +Q E Q   ++             + I+   +   LK EL ++ Q+   ++
Sbjct: 1010 KNLKEEIERIQKEVQEKEED------------KEQISTTEEVEELKNEL-IETQRL--LE 1054

Query: 1769 EERNVVESEHNVLSSEVENLKSEL 1698
            EER   ES    +S+E E  K ++
Sbjct: 1055 EERKEKES----ISNEFEETKEQV 1074


>gb|EGI67148.1| Cytochrome P450 6B3 [Acromyrmex echinatior]
          Length = 2102

 Score =  130 bits (326), Expect = 5e-27
 Identities = 187/922 (20%), Positives = 391/922 (42%), Gaps = 60/922 (6%)
 Frame = -3

Query: 3164 TKVHIREEESCKHLTE-ALENHIYGSLLESCVVDRE---AHIKQLMEQMNALVKEKRELE 2997
            +K+++  +++ K L +  +EN +    L+   V+     A    L  +M  L  E R+L 
Sbjct: 532  SKINVALDDAKKQLNKFEVENEVLTEELKKANVNNNKLLADFDTLQSEMAKLKSENRKLL 591

Query: 2996 NDAQRGEEISQSLKDEVFQLK-EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANN 2820
             +   G+E    L  E+  LK EV  +  +      E+ +    L+QK+ ++       N
Sbjct: 592  QEVDDGKEELTKLLSEIETLKKEVDNMSNKLTSANNEVVD----LQQKSVEL-------N 640

Query: 2819 NLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVN 2640
            N L++   I  +L   + + E +   +   M +    ++    +  E   Q+ LL D+VN
Sbjct: 641  NKLKEAQVINEQLRADIHQIEAENKDINAQMNNYRDENSRLNIKLNESKEQINLLTDEVN 700

Query: 2639 HLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKN 2460
             L+E L  A +   F+E QL  L+  K+ +  E+    +   KL  DL A S  +   + 
Sbjct: 701  KLREQLDNAENRIKFLEAQLVSLQTDKDKMQNEINALQNEISKLKLDLSAESTAKRDIQE 760

Query: 2459 QLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEG 2280
            +L+    + K L L+I+++       + E  LLK     + +    L   + E+  Q   
Sbjct: 761  ELVALKNEMKNLILKIDEMRVQNHALKEERDLLKKELLNLGEESLSLRAANAEMMNQINN 820

Query: 2279 ILKQDINIEDELARTKE----------VGRSATDMKKVNSDAGAKVSGILEM-LLPMKDD 2133
            +     +++ +L++ +E            + +TD   + ++   +   + ++    ++ +
Sbjct: 821  LKLDISDLQSQLSKAEEDIEYWKLENCKLKMSTDKLSIENEKKKEALNVCKVEHQTLEKE 880

Query: 2132 VFSLKEEVL---GNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAI 1962
            + +L+ E +   G I  L+N  + + ++    +  K E   E      EV+ L+ E+  +
Sbjct: 881  ITNLRNEKIKLEGEIAELKNLLEGLNLSSFAEKSAKEEAVKELTKFKNEVVALREELQTL 940

Query: 1961 QHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKA 1782
            +  L +L+ +N  ++D+ ++ + ++   K  L N  ++ + L   N +LK++++      
Sbjct: 941  KSELTKLRTENDKIRDKEEKLSSQVSTLKTELENAKNEILALRVDNDTLKSKIN------ 994

Query: 1781 FQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILL----GQHVEVASLD 1614
              + +E N ++SE N+L SEV+ LK E    ++    F + F+ L     GQ  E+ +L 
Sbjct: 995  -TLTDENNKLKSESNMLISEVDGLKLENTNMREERQKFEKEFDKLKGEDDGQKDEIKNL- 1052

Query: 1613 IESCRFAEEKLM-RILDELICLRNENAKLK----------------NEAL-YEYHDYERK 1488
             +S   AE+KL  +I  EL   ++EN +L+                N+ L  E  D ++ 
Sbjct: 1053 -KSNLTAEQKLSEKIRLELSTSQSENDRLRAELEKLQKNLDTLELVNDKLNSEVEDLKKT 1111

Query: 1487 NVSG-SRAEAMSVLISKSLGNGRANQREFQNKEEDSSGV-DLLKNKCTRLEFQVQKLSEK 1314
            ++   ++  A+   +++ L    A  +E  +   + S +  ++ +K  +   + + +   
Sbjct: 1112 SIDAQNKVNALQYHVAELLEEKEALLKELDSLRAEVSRLGKVVSDKVAKEAIEKKTIDSN 1171

Query: 1313 AEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGEL 1134
             ++ E    E  +M  + E +++ L+D+               SLK EN  L+ E     
Sbjct: 1172 GKLIEELKAELDKMRVENENLKRKLNDVNKQHI----------SLKDENAALKIENTKIA 1221

Query: 1133 TPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNR 954
            T   SFK    S +    + +E  T  +            +  T   E Q++  LM +N+
Sbjct: 1222 TELDSFK----SDLNRCRVDNERLTIELAASEARALEIQRE-RTDDKERQDLQNLMVENK 1276

Query: 953  KYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHV 774
            +  +++     +   L+ ++++ +                    D++S E +LK+  I +
Sbjct: 1277 ELRDKLRMAQNEINKLKENIKKSKGDFIEDAD------------DIDSFENELKKSMIEI 1324

Query: 773  MQLVEHNTRLKKDVKFGFAWANSMHDLN-GQEQKL---------------KVDEEVPILC 642
                    + ++D+K+     N +  +N G E +L               ++DEEV    
Sbjct: 1325 -------DKAREDLKYAAEENNKLKMINDGLELELSQLKALLDEIKDYPEQIDEEVNGTK 1377

Query: 641  HQNSKIAERLDI-NTDKARALD 579
             Q+ ++   L I N +    LD
Sbjct: 1378 DQSQRLLAALKIKNMELKSGLD 1399



 Score = 78.2 bits (191), Expect = 2e-11
 Identities = 121/593 (20%), Positives = 245/593 (41%), Gaps = 34/593 (5%)
 Frame = -3

Query: 2822 NNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDV 2643
            N  L+  +  + E    L+E+  +R    +  + V+ +       R+    +   +RD +
Sbjct: 110  NERLQNANEELAEKVRNLEESLAERDCCDDPCEKVKYVREKIAALRDRFAAEKKQMRDTI 169

Query: 2642 NHLKEALSMAVDDRAF-----MEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEK 2478
            +HLK  L  A +D +      +  +L++L    +   +++++ V R  + + DL    E 
Sbjct: 170  SHLKLKLMEAEEDTSCAALNRLRAKLRELMKDGQKADQQVSVVVERSMQTSVDLSKSYED 229

Query: 2477 EESTKNQLLIQTEQNKQLELEI---EKLYGSLQMKQMEN----TLLKDGNEKIYDLCKLL 2319
               T+      T+  + LE  +   E++   L  K+ +     + L++    + +L   L
Sbjct: 230  LLRTERLQAEPTQIRRTLEEVVTFSEEIDVPLSAKEEDIPALLSQLRNCKMLLAELKMHL 289

Query: 2318 ATKSREVQGQQEGILKQDINIEDELARTKE-VGRSATD----MKKVNSDAGAKVSGILEM 2154
              K+   +  Q  + K   +I   +    E + RSA D    MK+       ++  I E+
Sbjct: 290  DEKTAYTEALQSELNKLKASIVIPMVDLDEMIVRSAMDEVAEMKEEPEKPDKEIRKIQEL 349

Query: 2153 LLPMKDDVFSLKEEVLGNINSLRNDAQMVQVA---LEQMQDTKSELFAEAEIRAQEVLRL 1983
                ++D   +K E+      LR + +  QVA   LE M+D    L AE E   + +   
Sbjct: 350  SRVQEEDN-EMKSEIDKLNVDLRREEEKFQVAQKELEGMRDDLHSLGAENEFLKETLENA 408

Query: 1982 QAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAEL 1803
            + E +       ELK +N  L++      KEL +++   NN+ +    L S+N+ L+ EL
Sbjct: 409  KLETN-------ELKEENVALKNNLDNMIKELESSRRENNNIKTDLDQLLSENKYLRDEL 461

Query: 1802 HLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKD-------------LEGYFLR 1662
              Q  +  Q++ E    +   + L  E++ LK E  + KD              E   L+
Sbjct: 462  EKQVAETDQLKSEGIAWKEGFDKLLQEMDRLKVESDKLKDESATVKSERDNLTTERDNLK 521

Query: 1661 LFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNV 1482
                LL   +   ++ ++  +    K   + +E++    + A + N  L    D  +  +
Sbjct: 522  SENGLLKDDLSKINVALDDAKKQLNK-FEVENEVLTEELKKANVNNNKLLADFDTLQSEM 580

Query: 1481 SGSRAEAMSVLISKSLGNGRANQREFQNKEED-SSGVDLLKNKCTRLEFQVQKLSEKAEM 1305
            +  ++E   +L  + + +G+    +  ++ E     VD + NK T    +V  L +K+  
Sbjct: 581  AKLKSENRKLL--QEVDDGKEELTKLLSEIETLKKEVDNMSNKLTSANNEVVDLQQKSVE 638

Query: 1304 FETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEM 1146
               K +EAQ +  +L       +D+            ++ + + EN+RL  ++
Sbjct: 639  LNNKLKEAQVINEQLR------ADIHQIEAENKDINAQMNNYRDENSRLNIKL 685


>ref|XP_001310118.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
            gi|121891874|gb|EAX97188.1| viral A-type inclusion
            protein, putative [Trichomonas vaginalis G3]
          Length = 3977

 Score =  130 bits (326), Expect = 5e-27
 Identities = 175/885 (19%), Positives = 370/885 (41%), Gaps = 40/885 (4%)
 Frame = -3

Query: 3131 KHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNALVKEKRELENDAQRGEEISQSLKD 2952
            + L++  EN I      S +V +   ++QL++++N   KEK +L    Q  E ++++  +
Sbjct: 2570 EELSKKNENLINLQGTNSNLVLKNDELQQLIDKLN---KEKSDL---IQENERLTKNNGE 2623

Query: 2951 EVFQLKEVSRLYEEEKQHTIEL-QENFNALRQKNE---DICLKIEANNNLLEQKDNIIVE 2784
               +L+ + ++ E  K ++ E  +EN   + Q N+   D+  K++   N L+   + + E
Sbjct: 2624 SNEKLQSLDQMIETVKNNSSEKDKENHQIIDQLNKEKLDLSSKLKDYENQLDVLKSSLKE 2683

Query: 2783 LSHK-----------LQENEE---QRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDD 2646
            L+ K            QENE    + S+L+++  S++  + +   E EEL ++L     +
Sbjct: 2684 LNDKNKELQNGNDILKQENETLTPKISSLESENSSLKSTNEIKDKEIEELKQKL----SE 2739

Query: 2645 VNHLKEALSMAVDDRAFM-EKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEES 2469
            ++ L       +D R    EK+L++L NQ E +  E+ +   R ++L++  + L    E 
Sbjct: 2740 ISQLNSQHESDLDSRRKQFEKELEELRNQLEKLQNEIQIREQRGKELSNQNEELMNNLEK 2799

Query: 2468 TKNQLLIQTEQNKQLELEIEKLYGSLQMKQME-NTLLKDGNEKIYDLCKLLATKSREVQG 2292
             K++L       +  + E E L  SL+  Q   + L+ + +++I +L K L TK+ E   
Sbjct: 2800 MKSELNDAKMNKEHSDQENETLKKSLEENQQNYDQLVDELSKEIEELKKQLLTKAEESNS 2859

Query: 2291 QQEGILKQDINIEDEL-ARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKE 2115
             +  I        DEL ++ + +     ++K  N++              +K  + SLK 
Sbjct: 2860 SKHEI--------DELQSKIQNLSSENENLKSTNNE--------------LKQQIESLK- 2896

Query: 2114 EVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAI--------- 1962
                  N L+N  Q+V+   +++  +  +     E+  Q+ L L  +++ +         
Sbjct: 2897 ------NDLQNKDQIVEELTKEIDSSNKQSHENNELLNQKQLDLMKQIEDLTKKQGEMLK 2950

Query: 1961 -----QHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHL 1797
                 ++I+ +LK KN+ L  E     K +      LN+  S   NL ++N  LK+ L  
Sbjct: 2951 QNQNQENIINDLKIKNEELTKEGNNKDKVINELNKSLNDFKSLIQNLSNENEKLKSALQN 3010

Query: 1796 QAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASL 1617
                   +Q++ N  +     L +++E LK  L+E+K  E   +                
Sbjct: 3011 SQGNNADLQQKLNSTQQNDQNLLNQIELLKKSLQENKQNEDNLVN--------------- 3055

Query: 1616 DIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKS 1437
            +I++ +   +   +I+++L        + KNE L    + +++ +     +  S LISK 
Sbjct: 3056 EIQNQKIENQNKDQIIEDL--------RKKNEEL----NLKQQQIQDQFNKEKSGLISKL 3103

Query: 1436 LGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLE 1257
             G   +      N E+       L+ + + L  Q+  L +K E+   +     Q+  + +
Sbjct: 3104 QGLNLSGNELLSNNEK-------LEQEQSDLMNQINDLRKKNEILNQQQANNNQIIKECQ 3156

Query: 1256 EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINI 1077
            E                    ++++ ++ N  L+ ++   +  + + K++     K +  
Sbjct: 3157 E--------------------KIQNYEESNNELQRKLNEAMNNNENAKNQIDQLKKLLEE 3196

Query: 1076 GDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNS 897
              ++D  L++           +  ++     ++  L  D      +    +K+TQ   NS
Sbjct: 3197 TKQNDDKLVEELTKEIEKLKNEQQSKDQNINDLSALNKDKSSLIQQNDDLSKKTQEFYNS 3256

Query: 896  VQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFA 717
             Q   Q                      S++K L+  N    Q ++  T+ K D+     
Sbjct: 3257 QQNQAQMIEDLKK------------QNESLQKNLEINNNETQQNIDQLTKDKSDL----- 3299

Query: 716  WANSMHDLNGQEQKL-----KVDEEVPILCHQNSKIAERLDINTD 597
             A+ +HD   +   L     +++E+  I+  +N + +++L++N D
Sbjct: 3300 -ASKLHDYEAKINDLNSLIKELNEKNAIIEKKNYEFSQQLEVNND 3343



 Score =  126 bits (316), Expect = 7e-26
 Identities = 211/1012 (20%), Positives = 407/1012 (40%), Gaps = 114/1012 (11%)
 Frame = -3

Query: 3200 YYALQKKAGELQTKVHIRE---EESCKHLTEALENHIYGSL-----------LESCVVDR 3063
            Y  L  K    QTKV+  E   E+  K  TE   N+   +            L S   D 
Sbjct: 365  YNDLDAKNQNNQTKVNNLEKIIEKLIKENTELANNNKNNNSKIDELQNQNKDLISASNDM 424

Query: 3062 EAHIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQ 2883
                + L  +++ L KEK ELE   +  +   + LK ++    + S    E  Q  I+  
Sbjct: 425  NTKNQSLQTKIDQLNKEKTELEEKNKVLKSNLEGLKSDLLSKNQESTKKNENLQKIIDQL 484

Query: 2882 ENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHA 2703
            +N N L   N +   K+  N++L ++K ++  ++    + N++  S L+N+ +++E++  
Sbjct: 485  QNENKLLSSNLENQTKL--NDDLNKEKSDLQSKIEELEKNNKDLTSNLENNHKTIEELSN 542

Query: 2702 V---SQTEREELNRQLV---LLRDDVNHLKEALSMAVDDRAFMEKQLQDL-ENQKETVSK 2544
                 Q   +EL   L     L DD+N  K  L   +++ +   ++L+   +N+KE +  
Sbjct: 543  KINDLQNNNKELTSNLEDQNKLNDDLNKEKADLQSKIEELSTKNEELESSNKNEKENLQN 602

Query: 2543 ELALSVSREQKLASDLKALSEKEESTKNQL-----LIQTEQNK---------QLELEIEK 2406
            ++        +L  + + L E E+ +K  +     +I+   N+         QLE   + 
Sbjct: 603  KVDEFEKIIDQLRKEKEVLEENEKVSKTNIDDDYKVIEELNNEKSDLQSKIDQLEKNNKD 662

Query: 2405 LYGSLQMKQMENTLLKDGNE---KIYDLCKLLATKSREVQGQQEGILKQDINIEDELART 2235
            L  +L++   E + L   NE   K  D  K L  K+     + +  +++     ++L + 
Sbjct: 663  LTTNLELSNKEKSDLSLENENKRKEIDELKSLNNKTNNDIEKLQLQIQELEKSNEQLQKE 722

Query: 2234 KEVGRSATDMKKVNSDAGAKVSGILEM----LLPMKDDVFSLKEEVLGNINS-------L 2088
            KEV  S  +  K N +   K  GIL      L    +++ +  +E+  N+ +       L
Sbjct: 723  KEVLSSENNQLKSNVENSEKEIGILNKEKADLQSKVEELDNNNKELASNLENQNKLNKVL 782

Query: 2087 RNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDES 1908
             N+   +Q  +E++     EL +       E   LQA ++ ++ I+ EL+++N+ L+ ES
Sbjct: 783  NNENSDLQSKIEELTTKNQELESSNIETNNEKENLQARINELEKIIDELQKENENLETES 842

Query: 1907 -------QRNAKELWNAKARLNNVMSK---------------------NINLESQNRSLK 1812
                   Q N K + +     N++ SK                     N +L+++N  L+
Sbjct: 843  NHLRTDLQNNEKTIADLNKDKNDLTSKIGELEKNNKEFTTLIDKINASNKDLQTKNDELQ 902

Query: 1811 AELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSE----LKESKDLEGYFLRLFEILL 1644
            +++ L  +   Q+ ++++ + ++   L + ++ +K       KE+KDL+     L E   
Sbjct: 903  SKVDLLEKILDQLNKDKSDLITKLEELQTSIDQMKQTNENLNKENKDLQNKIEELLEEND 962

Query: 1643 GQHVEVASLDIE----SCRFAEEKL----------------MRILDELICLRNENAKLKN 1524
              + E  S + E      + AEEKL                 +I+DELI    +     N
Sbjct: 963  KANNENESKNKELQQIIDQLAEEKLSLQNKFEESEKNAKDNQKIIDELIAENEKLTSSNN 1022

Query: 1523 EALYEYHDY-----ERKNVSGSRAEAMSVLISKSLG-NGRANQREFQNKEEDSSGVDLLK 1362
            E   E         E K       E +S  I K    N    +       E+   +D LK
Sbjct: 1023 EEKVELESLKNSLEETKQNDDKLVEELSKEIEKLKNENNSILENSDSKNNENQQIIDQLK 1082

Query: 1361 NKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRS 1182
             + + L  QV KL++K E  E   ++     N+ +E  + ++D             ++  
Sbjct: 1083 KEKSDLMNQVDKLTKKNEDQEKVIQDLINDQNQKDEENKQMNDQ------SNELKSQIEK 1136

Query: 1181 LKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDT 1002
            +  EN  L+S+++         K   G  +KE  I   +   L +            ID 
Sbjct: 1137 ISIENETLKSDLQKN-------KESNGELMKEREISQSELEELKKLLEETKQNDNKLIDK 1189

Query: 1001 RTSETQEIDTLMD-DNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGG 825
              +E Q ++  +D +N+ +   +  FTK+   L + ++EL                    
Sbjct: 1190 LRNENQSLNNQLDMNNKDHQQIIDQFTKEESDLMSQIEELNALNNELNVNIQNLEQ---- 1245

Query: 824  IDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMH-DLNGQEQKLKVD----- 663
             D +++ KQ +ELN  + +    N  L  + +   +    +  +L   E+K K D     
Sbjct: 1246 -DKSNLTKQNEELNALLNETKLQNQNLSNENETLRSNNERLQSELKQNEEKSKSDFDQLT 1304

Query: 662  EEVPILCHQNSKIAERLDINTDKARALDMEVQRIRLILSRIPTKPTEEASKM 507
            +++  L  + S   + +D   +K   L+  + ++    ++I    T+   K+
Sbjct: 1305 KDLETLKSEQSNKDKMIDELQNKTNDLEESIGKLNEEKAKITDSLTDRDQKI 1356



 Score =  119 bits (299), Expect = 7e-24
 Identities = 183/845 (21%), Positives = 353/845 (41%), Gaps = 65/845 (7%)
 Frame = -3

Query: 3218 QKILEDYYALQKKAGELQTKVHIREEESCKH--LTEALENHIYGSLLESCVVDREAHIKQ 3045
            QK+ E     +  + E+     + EE +  H  L    EN      L+  + D++  I++
Sbjct: 1973 QKLDESQQTNENSSNEIDNLKKLLEEANNNHNQLMNDFEN------LKHEISDKDKMIQE 2026

Query: 3044 LMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNAL 2865
            L         EKR   N+ Q  + +S  LK+   ++ E+    E+ KQ   +L +  N L
Sbjct: 2027 L---------EKRNDANNNQNSD-LSAKLKESEAKISELDSQIEKYKQELEKLMKMNNEL 2076

Query: 2864 RQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTER 2685
            ++  +++        N ++   N  V L  ++ +++E  + LQND+   +Q +    ++ 
Sbjct: 2077 KETVQEM-------ENQIQNISNENVNLKTEVDKSKENSNKLQNDLNEAKQNNENLLSQI 2129

Query: 2684 EELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLA 2505
            E L +  +L  +D N   E +   ++D A M K+  D EN  ET+ K L  +     +L 
Sbjct: 2130 ESLKK--LLEENDANF--EKMKSELND-AKMNKEHSDQEN--ETLKKSLEENQQNYDQLV 2182

Query: 2504 SDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCK 2325
             +L   S++ E  K QLL + E++   + EI++L   +Q    EN  LK  N        
Sbjct: 2183 DEL---SKEIEELKKQLLTKAEESNSSKHEIDELQSKIQNLSSENENLKSTNN------- 2232

Query: 2324 LLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATD----MKKVNSDAGAKVSGILE 2157
                   E++   + ILK +  I  EL  TK+  +        +KKV  +       +++
Sbjct: 2233 -------ELKQNLDDILKNNEQINSELTETKQTNKDLLSQIESLKKVLEENKQNDEQLVD 2285

Query: 2156 MLLP----MK----------DDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFA 2019
             L      MK          D++   KE +   +NS   D Q +   +E+M   KSEL  
Sbjct: 2286 ELSKAPDEMKHEQQKKDNRIDELTKEKETLYNTLNSHDKDHQQI---IEEMNKEKSEL-- 2340

Query: 2018 EAEIRAQEVLRLQAEVDAIQHILIELKRKNQTL-QDESQ---------RNAKELWNAKAR 1869
                   ++   ++E+D ++ +  EL   N  L QD+S+         RN  +L NA+  
Sbjct: 2341 -----GSQIHEYESELDKLKSLNKELNENNTKLNQDKSELIKQNEDLTRNNNDLINAQND 2395

Query: 1868 LNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKES 1689
             + ++++N          KA++         +Q     + +E+N L  EVE L++EL +S
Sbjct: 2396 KDRIINEN----------KAKIDELPSLLNDLQSHLQNLSNENNSLKQEVEKLQTELGDS 2445

Query: 1688 KDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELIC-LRNENAKLKNEALY 1512
            K               Q+ E + ++ E  + + E+  +  ++L+  L  E  KLKNE L 
Sbjct: 2446 K---------------QNEEKSKIESEQMKKSLEETKQNDEQLVDELTKEIEKLKNEQLN 2490

Query: 1511 EYHDYE---------RKNVSGSRAEAMSVL--ISKSLGNGRANQREFQNK--------EE 1389
            +    +          KN+  +  E   ++  +++ L   ++   +++ K        +E
Sbjct: 2491 KDRTIQNLTNKNESINKNLDSNNKEYEQIIDQLNQDLSESKSKLNDYETKMNELNLLNKE 2550

Query: 1388 DSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXX 1209
                 + LK   + L  Q+++LS+K E           +  K +E+QQ +  +       
Sbjct: 2551 LQKDNETLKENQSDLINQIEELSKKNENLINLQGTNSNLVLKNDELQQLIDKLNKEKSDL 2610

Query: 1208 XXXXIRV-RSLKKENTRLRS--EMKGELTPSRSFKHREG-SFIKEINIGDEDDTPLIQXX 1041
                 R+ ++  + N +L+S  +M   +  + S K +E    I ++N    D +  ++  
Sbjct: 2611 IQENERLTKNNGESNEKLQSLDQMIETVKNNSSEKDKENHQIIDQLNKEKLDLSSKLKDY 2670

Query: 1040 XXXXXXXXXKIDTRTSETQEI----DTLMDDNRKYWNRVSHFTKQTQSLQNS-------V 894
                      +     + +E+    D L  +N     ++S    +  SL+++       +
Sbjct: 2671 ENQLDVLKSSLKELNDKNKELQNGNDILKQENETLTPKISSLESENSSLKSTNEIKDKEI 2730

Query: 893  QELQQ 879
            +EL+Q
Sbjct: 2731 EELKQ 2735



 Score =  117 bits (292), Expect = 4e-23
 Identities = 192/913 (21%), Positives = 381/913 (41%), Gaps = 79/913 (8%)
 Frame = -3

Query: 3056 HIKQLMEQMNALVKE--------KRELENDAQRGEEISQSL-KDEVFQLKEVSRLYEEEK 2904
            ++K+ ++++N   KE        ++ L+N+ Q  +++ Q L K++   + ++ +L  + K
Sbjct: 293  NLKKEIDELNNANKELNVKSINLQQSLDNEKQNNKKMIQDLNKEKTDLISKIEKLEMDNK 352

Query: 2903 QHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQ 2724
                E+    N +     D+  K + N   +   + II +L   ++EN E  +  +N+  
Sbjct: 353  ----EMNSKLNNVNTSYNDLDAKNQNNQTKVNNLEKIIEKL---IKENTELANNNKNNNS 405

Query: 2723 SVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSK 2544
             ++++        +  N+ L+   +D+N   ++L   +D    + K+  +LE + + +  
Sbjct: 406  KIDEL--------QNQNKDLISASNDMNTKNQSLQTKIDQ---LNKEKTELEEKNKVLKS 454

Query: 2543 ELALSVSREQKLASDLKALSEKEESTKN----QLLIQTEQNKQLELEIEKLYGSLQMKQM 2376
             L       + L SDL  LS+ +ESTK     Q +I   QN+  +L    L    ++   
Sbjct: 455  NL-------EGLKSDL--LSKNQESTKKNENLQKIIDQLQNEN-KLLSSNLENQTKLNDD 504

Query: 2375 ENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKV 2196
             N    D   KI +L K     +  ++   + I +    I D     KE+  +  D  K+
Sbjct: 505  LNKEKSDLQSKIEELEKNNKDLTSNLENNHKTIEELSNKINDLQNNNKELTSNLEDQNKL 564

Query: 2195 NSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAE 2016
            N D   + +      L  K +  S K E L + N  +N+ + +Q  +++ +    +L  E
Sbjct: 565  NDDLNKEKAD-----LQSKIEELSTKNEELESSN--KNEKENLQNKVDEFEKIIDQLRKE 617

Query: 2015 AEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQ---DESQRNAKELWNAKARLNNVMSKN 1845
             E+  +     +  +D    ++ EL  +   LQ   D+ ++N K+L      L+N    +
Sbjct: 618  KEVLEENEKVSKTNIDDDYKVIEELNNEKSDLQSKIDQLEKNNKDL-TTNLELSNKEKSD 676

Query: 1844 INLESQNR-----SLKA----------ELHLQAQKAF----QIQEERNVVESEHNVLSSE 1722
            ++LE++N+      LK+          +L LQ Q+      Q+Q+E+ V+ SE+N L S 
Sbjct: 677  LSLENENKRKEIDELKSLNNKTNNDIEKLQLQIQELEKSNEQLQKEKEVLSSENNQLKSN 736

Query: 1721 VENLKSEL----KESKDLEGYFLRL-------------------------------FEIL 1647
            VEN + E+    KE  DL+     L                                E L
Sbjct: 737  VENSEKEIGILNKEKADLQSKVEELDNNNKELASNLENQNKLNKVLNNENSDLQSKIEEL 796

Query: 1646 LGQHVEVASLDIESCRFAE------EKLMRILDELICLRNENAKLKNEALYEYHDYERKN 1485
              ++ E+ S +IE+    E       +L +I+DE   L+ EN  L+ E+ +   D +   
Sbjct: 797  TTKNQELESSNIETNNEKENLQARINELEKIIDE---LQKENENLETESNHLRTDLQNNE 853

Query: 1484 VSGSRAEAMSVLISKSLGNGRANQREFQN--KEEDSSGVDLLKNKCTRLEFQVQKLSEKA 1311
             + +        ++  +G    N +EF     + ++S  D L+ K   L+ +V  L    
Sbjct: 854  KTIADLNKDKNDLTSKIGELEKNNKEFTTLIDKINASNKD-LQTKNDELQSKVDLLE--- 909

Query: 1310 EMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELT 1131
            ++ +  +++   +  KLEE+Q ++  M               +L KEN  L+++++  L 
Sbjct: 910  KILDQLNKDKSDLITKLEELQTSIDQMKQTN----------ENLNKENKDLQNKIEELLE 959

Query: 1130 PSRSFKHREGSFIKEI-NIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNR 954
             +    +   S  KE+  I D+    L +                    + ID L+ +N 
Sbjct: 960  ENDKANNENESKNKELQQIIDQ----LAEEKLSLQNKFEESEKNAKDNQKIIDELIAENE 1015

Query: 953  KYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHV 774
            K  +  +    + +SL+NS++E +Q              K    + NSI +     N   
Sbjct: 1016 KLTSSNNEEKVELESLKNSLEETKQNDDKLVEELSKEIEKLKN-ENNSILENSDSKNNEN 1074

Query: 773  MQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEEVPILCHQNSKIAERLDINTDK 594
             Q+++   +LKK+        + +   N  ++K+  D    ++  QN K  E   +N D+
Sbjct: 1075 QQIID---QLKKEKSDLMNQVDKLTKKNEDQEKVIQD----LINDQNQKDEENKQMN-DQ 1126

Query: 593  ARALDMEVQRIRL 555
            +  L  ++++I +
Sbjct: 1127 SNELKSQIEKISI 1139



 Score =  114 bits (286), Expect = 2e-22
 Identities = 197/1017 (19%), Positives = 419/1017 (41%), Gaps = 110/1017 (10%)
 Frame = -3

Query: 3227 AQHQKILEDYYALQKKAGELQTKVHIRE--EESCKHLTEALENHIYGSLLESCVVDREAH 3054
            A   K  ++   L+ +  +LQ ++ IRE  E+   +  E L N +    ++S + D   +
Sbjct: 1463 ANKDKSEKELEELRNELEKLQNEIQIREQREKELSNQNEELMNIL--EKMKSELNDVNMN 1520

Query: 3053 IKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEK---QHTI-EL 2886
             +QL ++   L   K+ LE + Q  +++   L  E+  LK+     + +    +H I EL
Sbjct: 1521 NEQLDQEKEIL---KKSLEENQQNYDQLIDELSKEIEVLKKQLLTKDADSNSSKHEIDEL 1577

Query: 2885 QENFNALRQKNEDICLKIEANNNLLEQKDNIIV---ELSHKLQENEEQRSALQNDMQSVE 2715
            Q     L  +NE++      NN L +  D+I+    +++ +L E ++    L + ++S++
Sbjct: 1578 QSKIQNLSSENENLK---STNNELKQNLDDILKNNEQINSELTETKQTNKDLLSQIESLK 1634

Query: 2714 QMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELA 2535
            ++   ++   E+L  +L    D++ H ++     +D    + K+ + L N   +  K+  
Sbjct: 1635 KVLEENKQNDEQLVDELSKAPDEMKHEQQKKDNRIDK---LTKEKETLHNTLNSHDKDHQ 1691

Query: 2534 LSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENT---- 2367
              +    K  S+L++  EK +S   +L    E N +L  +  +L    +    +N     
Sbjct: 1692 QIIEEMNKEKSELESELEKLKSLNKEL---NENNTKLNQDKSELIKQNEDLTNDNNHKDE 1748

Query: 2366 LLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSAT----DMKK 2199
             + +   KI +L  LL     +++ Q + +  ++ +++ E+ + KE          D K+
Sbjct: 1749 FINENQVKIDELSSLL----NDLKSQLQNLSNENDSLKQEIEKQKETNEKLQSELEDSKE 1804

Query: 2198 VNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDA----QMVQVALEQMQDTKS 2031
                + +++  I + L   K +   L +E+   I  L+N+     Q +    ++ Q   S
Sbjct: 1805 NLEKSKSEIDPIQKSLEETKQNDEQLVDELTKEIEKLKNEQMTKDQKIDELTKENQSLNS 1864

Query: 2030 ELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKE------------- 1890
             L    +   Q + +L  E    +  L ELK+ +  L D+ +  AK+             
Sbjct: 1865 SLEDNNKENDQIIDQLNKEKSDYESKLNELKQDHSDLMDQIESLAKKNDELIKENNNKDQ 1924

Query: 1889 -LWNAKARLNNVMSKNINLESQ-------NRSLKAELHLQAQKAFQIQEERNVVESEHNV 1734
             + +   R+  ++S +  L+ Q       N SLK+E+    +   ++Q++ +  +  +  
Sbjct: 1925 IINDNNQRIEELVSLSNKLKPQIEVLSKENESLKSEIQRNHENIEKLQQKLDESQQTNEN 1984

Query: 1733 LSSEVENLKSELKESKDLEGYFLRLFEIL---------LGQHVE-------------VAS 1620
             S+E++NLK  L+E+ +     +  FE L         + Q +E              A 
Sbjct: 1985 SSNEIDNLKKLLEEANNNHNQLMNDFENLKHEISDKDKMIQELEKRNDANNNQNSDLSAK 2044

Query: 1619 LDIESCRFAE-----EKLMRILDELICLRNENAKLKNEALYEYHDYERKNVS----GSRA 1467
            L     + +E     EK  + L++L+ + NE  +   E   +  +   +NV+      ++
Sbjct: 2045 LKESEAKISELDSQIEKYKQELEKLMKMNNELKETVQEMENQIQNISNENVNLKTEVDKS 2104

Query: 1466 EAMSVLISKSLGNGRANQREFQNK--------EEDSSGVDLLKNKCTRLEFQVQKLSEKA 1311
            +  S  +   L   + N     ++        EE+ +  + +K++    +   +   ++ 
Sbjct: 2105 KENSNKLQNDLNEAKQNNENLLSQIESLKKLLEENDANFEKMKSELNDAKMNKEHSDQEN 2164

Query: 1310 EMFETKSREAQQ--------MANKLEEMQQTL----SDMXXXXXXXXXXXIRVRSLKKEN 1167
            E  +    E QQ        ++ ++EE+++ L     +             ++++L  EN
Sbjct: 2165 ETLKKSLEENQQNYDQLVDELSKEIEELKKQLLTKAEESNSSKHEIDELQSKIQNLSSEN 2224

Query: 1166 TRLRS---EMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRT 996
              L+S   E+K  L        +  S + E    ++D    I+             +   
Sbjct: 2225 ENLKSTNNELKQNLDDILKNNEQINSELTETKQTNKDLLSQIESLKKVLEENKQNDEQLV 2284

Query: 995  SETQEI-DTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGID 819
             E  +  D +  + +K  NR+   TK+ ++L N++    +              + G   
Sbjct: 2285 DELSKAPDEMKHEQQKKDNRIDELTKEKETLYNTLNSHDKDHQQIIEEMNKEKSELGS-Q 2343

Query: 818  MNSIEKQLKELNIHVMQLVEHNTRLKKD----VKFGFAWANSMHDL-NGQ--------EQ 678
            ++  E +L +L     +L E+NT+L +D    +K       + +DL N Q        E 
Sbjct: 2344 IHEYESELDKLKSLNKELNENNTKLNQDKSELIKQNEDLTRNNNDLINAQNDKDRIINEN 2403

Query: 677  KLKVDEEVPILCHQNSKIAERLDINTDKARALDMEVQRIRLILSRIPTKPTEEASKM 507
            K K+DE   +L    + +   L   +++  +L  EV++++  L    +K  EE SK+
Sbjct: 2404 KAKIDELPSLL----NDLQSHLQNLSNENNSLKQEVEKLQTELG--DSKQNEEKSKI 2454



 Score =  112 bits (280), Expect = 1e-21
 Identities = 185/914 (20%), Positives = 372/914 (40%), Gaps = 75/914 (8%)
 Frame = -3

Query: 3056 HIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVS-RLYEEEKQHTIELQE 2880
            +I+ L +  + L K+  EL       +  +Q+L +E   L+  + RL  E KQ+  + + 
Sbjct: 1239 NIQNLEQDKSNLTKQNEELNALLNETKLQNQNLSNENETLRSNNERLQSELKQNEEKSKS 1298

Query: 2879 NFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDM--------- 2727
            +F+ L +  E   LK E +N     KD +I EL +K  + EE    L  +          
Sbjct: 1299 DFDQLTKDLET--LKSEQSN-----KDKMIDELQNKTNDLEESIGKLNEEKAKITDSLTD 1351

Query: 2726 --QSVEQMHAVS----------QTEREELNRQLVLLRD---DVNHLKEALSMAVDDRAFM 2592
              Q +EQ++             +  ++ELN ++  L     D+N   E L   +      
Sbjct: 1352 RDQKIEQLNKEKSDLISDINNFEASQKELNDKIDSLNSANKDLNQENEKLKSQISSLENE 1411

Query: 2591 EKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNK------ 2430
               LQ   N K+   K +   +S       + K+  E E    +  L   E NK      
Sbjct: 1412 NSSLQSANNSKDKEIKSINQQLSETISSFDNYKSQHESEAEALSNKLNNLEANKDKSEKE 1471

Query: 2429 --QLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQ------GQQEGIL 2274
              +L  E+EKL   +Q+++     L + NE++ ++ + + ++  +V        Q++ IL
Sbjct: 1472 LEELRNELEKLQNEIQIREQREKELSNQNEELMNILEKMKSELNDVNMNNEQLDQEKEIL 1531

Query: 2273 KQDI--------NIEDELARTKEVGRSATDMKKVNSDAGA----KVSGILEMLLPMKDDV 2130
            K+ +         + DEL++  EV +     K  +S++      ++   ++ L    +++
Sbjct: 1532 KKSLEENQQNYDQLIDELSKEIEVLKKQLLTKDADSNSSKHEIDELQSKIQNLSSENENL 1591

Query: 2129 FSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHIL 1950
             S   E+  N++ +  + + +   L + + T  +L               +++++++ +L
Sbjct: 1592 KSTNNELKQNLDDILKNNEQINSELTETKQTNKDLL--------------SQIESLKKVL 1637

Query: 1949 IELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQ 1770
             E K+ ++ L DE  +   E+ + + + +N + K   L  +  +L   L+   +   QI 
Sbjct: 1638 EENKQNDEQLVDELSKAPDEMKHEQQKKDNRIDK---LTKEKETLHNTLNSHDKDHQQII 1694

Query: 1769 EERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAE 1590
            EE N  +SE   L SE+E LKS  KE  +      +    L+ Q+ ++ + +     F  
Sbjct: 1695 EEMNKEKSE---LESELEKLKSLNKELNENNTKLNQDKSELIKQNEDLTNDNNHKDEFIN 1751

Query: 1589 EKLMRILDELIC-----------LRNENAKLK---------NEALYEYHDYERKNVSGSR 1470
            E  ++I DEL             L NEN  LK         NE L    +  ++N+  S+
Sbjct: 1752 ENQVKI-DELSSLLNDLKSQLQNLSNENDSLKQEIEKQKETNEKLQSELEDSKENLEKSK 1810

Query: 1469 AEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAE----MF 1302
            +E     I KSL   + N    Q  +E +  ++ LKN+    + ++ +L+++ +      
Sbjct: 1811 SEIDP--IQKSLEETKQNDE--QLVDELTKEIEKLKNEQMTKDQKIDELTKENQSLNSSL 1866

Query: 1301 ETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSR 1122
            E  ++E  Q+ ++L + +                  ++  LK++++ L  +++       
Sbjct: 1867 EDNNKENDQIIDQLNKEKSDYES-------------KLNELKQDHSDLMDQIE------- 1906

Query: 1121 SFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWN 942
            S   +    IKE N  D       Q            +        +I+ L  +N    +
Sbjct: 1907 SLAKKNDELIKENNNKD-------QIINDNNQRIEELVSLSNKLKPQIEVLSKENESLKS 1959

Query: 941  RVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLV 762
             +    +  + LQ  + E QQ                   ++++++K L+E N +  QL+
Sbjct: 1960 EIQRNHENIEKLQQKLDESQQTNEN------------SSNEIDNLKKLLEEANNNHNQLM 2007

Query: 761  EHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEEVPILCHQNSKIAERLDINTDKARAL 582
                 LK ++        S  D   QE + + D       +QNS ++ +L  +  K   L
Sbjct: 2008 NDFENLKHEI--------SDKDKMIQELEKRNDAN----NNQNSDLSAKLKESEAKISEL 2055

Query: 581  DMEVQRIRLILSRI 540
            D ++++ +  L ++
Sbjct: 2056 DSQIEKYKQELEKL 2069



 Score =  104 bits (260), Expect = 2e-19
 Identities = 172/846 (20%), Positives = 338/846 (39%), Gaps = 14/846 (1%)
 Frame = -3

Query: 3050 KQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFN 2871
            +Q++E+MN   KEK EL +     E           +L ++  L +E  ++  +L ++ +
Sbjct: 2327 QQIIEEMN---KEKSELGSQIHEYES----------ELDKLKSLNKELNENNTKLNQDKS 2373

Query: 2870 ALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQT 2691
             L ++NED+        N    KD II E   K+ E     + LQ+ +Q++         
Sbjct: 2374 ELIKQNEDLTRNNNDLINAQNDKDRIINENKAKIDELPSLLNDLQSHLQNLSN------- 2426

Query: 2690 EREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSR--E 2517
            E   L +++  L+ ++   K+    +  +   M+K L++ +   E +  EL   + +   
Sbjct: 2427 ENNSLKQEVEKLQTELGDSKQNEEKSKIESEQMKKSLEETKQNDEQLVDELTKEIEKLKN 2486

Query: 2516 QKLASD--LKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEK 2343
            ++L  D  ++ L+ K ES    L      NK+ E  I++L   L   + +   L D   K
Sbjct: 2487 EQLNKDRTIQNLTNKNESINKNL---DSNNKEYEQIIDQLNQDLSESKSK---LNDYETK 2540

Query: 2342 IYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGI 2163
            + +L  L    ++E+Q   E + +   ++ +++    +   +  +++  NS+        
Sbjct: 2541 MNELNLL----NKELQKDNETLKENQSDLINQIEELSKKNENLINLQGTNSN-------- 2588

Query: 2162 LEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRL 1983
                L +K+D     ++++  +N  ++D       L +     +E     +   + V   
Sbjct: 2589 ----LVLKNDEL---QQLIDKLNKEKSDLIQENERLTKNNGESNEKLQSLDQMIETVKNN 2641

Query: 1982 QAEVDAIQHILIE-LKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAE 1806
             +E D   H +I+ L ++   L  + +    +L   K+ L  +  KN  L++ N  LK E
Sbjct: 2642 SSEKDKENHQIIDQLNKEKLDLSSKLKDYENQLDVLKSSLKELNDKNKELQNGNDILKQE 2701

Query: 1805 LHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEV 1626
                  K   ++ E + ++S + +   E+E LK +L E   L             QH   
Sbjct: 2702 NETLTPKISSLESENSSLKSTNEIKDKEIEELKQKLSEISQLNS-----------QHES- 2749

Query: 1625 ASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLI 1446
               D++S R   EK      EL  LRN+  KL+NE   +  +   K +S    E M+ L 
Sbjct: 2750 ---DLDSRRKQFEK------ELEELRNQLEKLQNE--IQIREQRGKELSNQNEELMNNLE 2798

Query: 1445 S-KSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFE----TKSREA 1281
              KS  N     +E  ++E ++    L +N+    +  V +LS++ E  +    TK+ E+
Sbjct: 2799 KMKSELNDAKMNKEHSDQENETLKKSLEENQ-QNYDQLVDELSKEIEELKKQLLTKAEES 2857

Query: 1280 QQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRS---EMKGELTPSRSFKH 1110
                ++++E+Q                  ++++L  EN  L+S   E+K ++   ++   
Sbjct: 2858 NSSKHEIDELQS-----------------KIQNLSSENENLKSTNNELKQQIESLKNDLQ 2900

Query: 1109 REGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSH 930
             +   ++E+    E D+   Q           ++D           LM        +   
Sbjct: 2901 NKDQIVEELT--KEIDSSNKQSHENNELLNQKQLD-----------LMKQIEDLTKKQGE 2947

Query: 929  FTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNT 750
              KQ Q+ +N + +L+                     +N + K L +    +  L   N 
Sbjct: 2948 MLKQNQNQENIINDLKIKNEELTKEGNNKDKV-----INELNKSLNDFKSLIQNLSNENE 3002

Query: 749  RLKKDVKFGFAWANSMHDLNGQEQKL-KVDEEVPILCHQNSKIAERLDINTDKARALDME 573
            +LK       A  NS  +    +QKL    +    L +Q   + + L  N      L  E
Sbjct: 3003 KLKS------ALQNSQGNNADLQQKLNSTQQNDQNLLNQIELLKKSLQENKQNEDNLVNE 3056

Query: 572  VQRIRL 555
            +Q  ++
Sbjct: 3057 IQNQKI 3062



 Score =  104 bits (259), Expect = 3e-19
 Identities = 149/711 (20%), Positives = 308/711 (43%), Gaps = 63/711 (8%)
 Frame = -3

Query: 3173 ELQTKVHIREE---ESCKHLTEALENHIYGS----LLESCVVDREAHIKQLMEQMNALVK 3015
            E Q K+   EE   E  + L EA+ N+         L+  + + + +  +L+E+   L K
Sbjct: 3154 ECQEKIQNYEESNNELQRKLNEAMNNNENAKNQIDQLKKLLEETKQNDDKLVEE---LTK 3210

Query: 3014 EKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNA----------L 2865
            E  +L+N+ Q  +   Q++ D     K+ S L ++    + + QE +N+          L
Sbjct: 3211 EIEKLKNEQQSKD---QNINDLSALNKDKSSLIQQNDDLSKKTQEFYNSQQNQAQMIEDL 3267

Query: 2864 RQKNEDICLKIEANNNLLEQKDNIIV----ELSHKLQENEEQRSALQNDMQSVEQMHAVS 2697
            +++NE +   +E NNN  +Q  + +     +L+ KL + E + + L + ++ + + +A+ 
Sbjct: 3268 KKQNESLQKNLEINNNETQQNIDQLTKDKSDLASKLHDYEAKINDLNSLIKELNEKNAII 3327

Query: 2696 QTEREELNRQLVLLRDDV---NHLKEALSMAVDDRAFMEKQLQDLENQKETVSKEL---- 2538
            + +  E ++QL +  D +   N L++ +     D+  + KQ+QDL N+   ++ +L    
Sbjct: 3328 EKKNYEFSQQLEVNNDLISKNNQLQQTIDQLNKDKTVLSKQIQDLANKNNEITNQLNNKD 3387

Query: 2537 ALSVSREQK----------LASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQ 2388
             + +  +QK          L  +L  L    +   +Q+    +  + L+L+IEK    LQ
Sbjct: 3388 KIILESKQKSDELNQSLSNLMKELHTLKANNDDLNSQISQSKQNEENLQLQIEKQKKLLQ 3447

Query: 2387 -MKQMENTLLKDGNEKIYDLCKLLATKSREV----QGQQEGILKQ------DINIEDELA 2241
              KQ +N L+ D ++++  L      K+ E+      +  GILKQ      +IN E E  
Sbjct: 3448 DTKQNDNKLVDDLSKEVETLTS-EKLKNEEIIKQNNAKYSGILKQLQQKNEEINKEKEQF 3506

Query: 2240 RTKEVGRSATDMKKVN---------SDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSL 2088
            +    G    + K VN         S    K+   L       + + +  ++   NI  L
Sbjct: 3507 KHDLEGEKQKNEKLVNDLNQTKDKLSQENEKLKHYLVAFKQNNEQITADNKQKDENIQQL 3566

Query: 2087 RNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDES 1908
                  ++  L++ +  KS+     E     + +L  E  ++ H L E  + N+ L   +
Sbjct: 3567 MKQINSLKSQLQEDEKLKSQFAKMKENYDSLINKLNQENKSLTHSLNESLKHNEELSKNN 3626

Query: 1907 QRNAKELWNAKARLNNVMSKNIN----LESQNRSLKAELHLQAQKAFQIQEERNVVESEH 1740
            ++  +       +LN + S++ N    +E+ N+ L+   +   QK  Q+ EE N ++   
Sbjct: 3627 EKLQQNNELLSNKLNQLGSQDNNKQKEIENMNQKLQKVSNEGKQKEDQLIEEINNLKFSL 3686

Query: 1739 NVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL 1560
              L  + E++   L E+K       +  E+L  Q+ E+  L  E    ++ K     DE+
Sbjct: 3687 IELQRKNEDMNQMLSETK-------KQNEVLSEQNNEIQLLKNELENLSKSK----EDEI 3735

Query: 1559 ICLRNE-NAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDS 1383
              L+ E   K+K +     H  E  N    + E+      +  G       E+++K++++
Sbjct: 3736 NSLKEEYERKIKEKEDEIEHLEENCNNEKKKTESYEKKFVEEKG-------EYESKQQNT 3788

Query: 1382 SGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDM 1230
                  +     LE +++ L ++ E  +    +   + ++  ++++ L+ +
Sbjct: 3789 ------ETYIEELETEIELLLKENEQLDKTKYDYDAIQHEYNKVREDLAKL 3833



 Score = 97.8 bits (242), Expect = 3e-17
 Identities = 162/746 (21%), Positives = 317/746 (42%), Gaps = 52/746 (6%)
 Frame = -3

Query: 3215 KILEDYYALQKKAGELQTKVHIREEESCKHLTEALEN----HIYGSLLESCVVDREAHIK 3048
            +I+ED   L+KK  EL  K    +++  K  +  +      ++ G+ L S     E    
Sbjct: 3069 QIIED---LRKKNEELNLKQQQIQDQFNKEKSGLISKLQGLNLSGNELLSNNEKLEQEQS 3125

Query: 3047 QLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNA 2868
             LM Q+N L K+   L        +I +  ++++       + YEE      ELQ   N 
Sbjct: 3126 DLMNQINDLRKKNEILNQQQANNNQIIKECQEKI-------QNYEESNN---ELQRKLNE 3175

Query: 2867 LRQKNEDICLKIEANNNLLEQK----DNIIVELSHKLQENEEQRSALQNDMQSVEQ-MHA 2703
                NE+   +I+    LLE+     D ++ EL+ ++++       L+N+ QS +Q ++ 
Sbjct: 3176 AMNNNENAKNQIDQLKKLLEETKQNDDKLVEELTKEIEK-------LKNEQQSKDQNIND 3228

Query: 2702 VSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVS 2523
            +S   +++ +  L+   DD++   +    +  ++A M   ++DL+ Q E++ K L ++ +
Sbjct: 3229 LSALNKDKSS--LIQQNDDLSKKTQEFYNSQQNQAQM---IEDLKKQNESLQKNLEINNN 3283

Query: 2522 REQ-------KLASDLKALSEKEESTKNQL--LIQTEQNKQLELEIEKLYGSLQMKQMEN 2370
              Q       K  SDL +     E+  N L  LI+    K   +E +K Y   Q  ++ N
Sbjct: 3284 ETQQNIDQLTKDKSDLASKLHDYEAKINDLNSLIKELNEKNAIIE-KKNYEFSQQLEVNN 3342

Query: 2369 TLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNS 2190
             L+   N+    + +L   K + V  +Q         I+D   +  E+     +  K+  
Sbjct: 3343 DLISKNNQLQQTIDQL--NKDKTVLSKQ---------IQDLANKNNEITNQLNNKDKIIL 3391

Query: 2189 DAGAKVSGILEMLLPMKDDVFSLK---EEVLGNINSLRNDAQMVQVALEQ----MQDTK- 2034
            ++  K   + + L  +  ++ +LK   +++   I+  + + + +Q+ +E+    +QDTK 
Sbjct: 3392 ESKQKSDELNQSLSNLMKELHTLKANNDDLNSQISQSKQNEENLQLQIEKQKKLLQDTKQ 3451

Query: 2033 ------SELFAEAEIRAQEVLR----LQAEVDAIQHILIELKRKNQTLQDESQRNAKELW 1884
                   +L  E E    E L+    ++        IL +L++KN+ +  E ++   +L 
Sbjct: 3452 NDNKLVDDLSKEVETLTSEKLKNEEIIKQNNAKYSGILKQLQQKNEEINKEKEQFKHDLE 3511

Query: 1883 NAKAR----LNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVE 1716
              K +    +N++      L  +N  LK  L    Q   QI  +    +     L  ++ 
Sbjct: 3512 GEKQKNEKLVNDLNQTKDKLSQENEKLKHYLVAFKQNNEQITADNKQKDENIQQLMKQIN 3571

Query: 1715 NLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENA 1536
            +LKS+L+E + L+  F ++ E          SL I       + L   L+E +   NE  
Sbjct: 3572 SLKSQLQEDEKLKSQFAKMKE-------NYDSL-INKLNQENKSLTHSLNESL-KHNEEL 3622

Query: 1535 KLKNEALYEYHDY--ERKNVSGSR-------AEAMSVLISKSLGNGRANQREFQNKEEDS 1383
               NE L + ++    + N  GS+        E M+  + K    G+  Q+E Q  EE +
Sbjct: 3623 SKNNEKLQQNNELLSNKLNQLGSQDNNKQKEIENMNQKLQKVSNEGK--QKEDQLIEEIN 3680

Query: 1382 S---GVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXX 1212
            +    +  L+ K   +   + +  ++ E+   ++ E Q + N+LE + ++  D       
Sbjct: 3681 NLKFSLIELQRKNEDMNQMLSETKKQNEVLSEQNNEIQLLKNELENLSKSKED------- 3733

Query: 1211 XXXXXIRVRSLKKENTRLRSEMKGEL 1134
                   + SLK+E  R   E + E+
Sbjct: 3734 ------EINSLKEEYERKIKEKEDEI 3753



 Score = 93.6 bits (231), Expect = 5e-16
 Identities = 166/881 (18%), Positives = 359/881 (40%), Gaps = 16/881 (1%)
 Frame = -3

Query: 3053 IKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENF 2874
            +KQ + +   L K  REL  +    E+IS+S++D       V R++ + +      +++ 
Sbjct: 95   VKQQIVKARKLAKHLRELNYE----EDISESIQDTSLNEDRVKRVFIDNQNLMKNYEDDL 150

Query: 2873 NALRQKNEDICLK-IEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVS 2697
            N    KN    L   E   + ++    II  +  +  + + +    QN +  + Q + + 
Sbjct: 151  NHTTPKNPHPNLDDSEVLPDNMDDSSLIIENVRTRDFKFDPEELNQQNTLDELTQNNEIL 210

Query: 2696 QTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSRE 2517
              + E+L+++     + +N    +LS  +        +L++   Q ++ +KEL+      
Sbjct: 211  SKDNEKLSKE----NEQLNQENTSLSTLLGSAKSTNLELENTIEQLKSANKELSDKNVEI 266

Query: 2516 QKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIY 2337
            Q    +L+   E+  ST ++LL +TE  K+   E+      L +K + N      NEK  
Sbjct: 267  QAKLINLQKEKEQLTSTNDKLLTETENLKKEIDELNNANKELNVKSI-NLQQSLDNEK-Q 324

Query: 2336 DLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILE 2157
            +  K++   ++E       I K +++ ++  ++   V  S  D+   N +   KV+ + +
Sbjct: 325  NNKKMIQDLNKEKTDLISKIEKLEMDNKEMNSKLNNVNTSYNDLDAKNQNNQTKVNNLEK 384

Query: 2156 MLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQA 1977
            ++           E+++     L N+ +     ++++Q+   +L + +     +   LQ 
Sbjct: 385  II-----------EKLIKENTELANNNKNNNSKIDELQNQNKDLISASNDMNTKNQSLQT 433

Query: 1976 EVDAIQHILIELKRKNQTLQDESQRNAKELWN---AKARLNNVMSKNIN-LESQNRSLKA 1809
            ++D +     EL+ KN+ L+   +    +L +      + N  + K I+ L+++N+ L +
Sbjct: 434  KIDQLNKEKTELEEKNKVLKSNLEGLKSDLLSKNQESTKKNENLQKIIDQLQNENKLLSS 493

Query: 1808 ELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVE 1629
             L  Q +    + +E++ ++S+   L    ++L S L+ +             L   + E
Sbjct: 494  NLENQTKLNDDLNKEKSDLQSKIEELEKNNKDLTSNLENNHKTIEELSNKINDLQNNNKE 553

Query: 1628 VASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVL 1449
            + S ++E      + L +   +L   + E    KNE L   +  E++N+     E   ++
Sbjct: 554  LTS-NLEDQNKLNDDLNKEKADLQS-KIEELSTKNEELESSNKNEKENLQNKVDEFEKII 611

Query: 1448 --ISKSLGNGRANQREFQ-NKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFET------ 1296
              + K       N++  + N ++D   ++ L N+ + L+ ++ +L +  +   T      
Sbjct: 612  DQLRKEKEVLEENEKVSKTNIDDDYKVIEELNNEKSDLQSKIDQLEKNNKDLTTNLELSN 671

Query: 1295 --KSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSR 1122
              KS  + +  NK +E+ +  S             ++++ L+K N +L+ E +   + + 
Sbjct: 672  KEKSDLSLENENKRKEIDELKSLNNKTNNDIEKLQLQIQELEKSNEQLQKEKEVLSSENN 731

Query: 1121 SFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWN 942
              K    +  KEI I +++   L                   ++ +    L ++N    +
Sbjct: 732  QLKSNVENSEKEIGILNKEKADLQSKVEELDNNNKELASNLENQNKLNKVLNNENSDLQS 791

Query: 941  RVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLV 762
            ++   T + Q L++S  E                       +N +EK + EL      L 
Sbjct: 792  KIEELTTKNQELESSNIETNNEKENLQAR------------INELEKIIDELQKENENLE 839

Query: 761  EHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEEVPILCHQNSKIAERLDINTDKARAL 582
              +  L+ D++       ++ DLN  +  L             SKI E L+ N  +   L
Sbjct: 840  TESNHLRTDLQNN---EKTIADLNKDKNDL------------TSKIGE-LEKNNKEFTTL 883

Query: 581  DMEVQRIRLILSRIPTKPTEEASKMRVPLRAFLVGSKKDQS 459
               + +I      + TK  E  SK+ + L   L    KD+S
Sbjct: 884  ---IDKINASNKDLQTKNDELQSKVDL-LEKILDQLNKDKS 920


>ref|XP_975536.2| PREDICTED: similar to viral A-type inclusion protein, putative
            [Tribolium castaneum] gi|270010587|gb|EFA07035.1|
            hypothetical protein TcasGA2_TC010007 [Tribolium
            castaneum]
          Length = 2246

 Score =  129 bits (324), Expect = 8e-27
 Identities = 157/700 (22%), Positives = 313/700 (44%), Gaps = 37/700 (5%)
 Frame = -3

Query: 3218 QKILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLM 3039
            QK+  DY  L+ K  + +T++    E     L   LE       +   +V+RE ++ QL 
Sbjct: 680  QKLQLDYSELETKLNDAKTQL----ENLTVELNTVLEEK---KSVAERLVEREDYVLQLE 732

Query: 3038 EQMNALVKEKRELEND----AQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFN 2871
            E+   L ++   LE+     +Q+ EE+    +D + QL +VS+  E  KQ    LQE   
Sbjct: 733  EEKKILTEKTNVLEDSYRKLSQKCEEVQSYNEDVLKQLSDVSQSLEISKQEIGSLQELKK 792

Query: 2870 ALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQT 2691
            +L  + E+    +E     LEQ  +  V+++  LQE E   + L    +  E +    +T
Sbjct: 793  SLELQLEESQTSLETLKVELEQMQSANVKINSLLQETE---ATLHQSKKESEDLKIQIET 849

Query: 2690 EREELNRQLVLLRD---DVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSR 2520
             ++ELN  +  LR+   DV  L+E+ +   ++   +E + ++L+++ E V  E +   + 
Sbjct: 850  LQQELNDSINNLRESQKDVFDLQESKNRVEENLKQVELESKNLKSELEKVHLEKS---TN 906

Query: 2519 EQKLASDLKALSE-KEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEK 2343
            +++L+   K+L+E +EES K +   +TE    L+ ++    GSL+         K   EK
Sbjct: 907  DKELSEVKKSLTELEEESEKEKHHFETEIG-VLQSQLNDALGSLE-------TAKKKEEK 958

Query: 2342 IYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGI 2163
            + +L   L T+ +E Q  +E +  +   + + L+ T++    A  +KK            
Sbjct: 959  LQNLKNQLETQLKETQAAEEKLKLEVEKLSNNLSETRQ--ERADFLKK------------ 1004

Query: 2162 LEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSEL---FAEAEIRAQEV 1992
            LE L     ++    +E+   ++ + +D +      +Q+ D ++ L     EAE    ++
Sbjct: 1005 LENLEDENGNLLKESQELQERLSQVLSDLESKTAESKQLNDIQTTLETRLDEAEKMRLQL 1064

Query: 1991 LRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLK 1812
              +Q+ +D  Q    ELK++   L++E     +     + +LN        LE +N  + 
Sbjct: 1065 ETIQSHLDETQSNYEELKKEKSLLENEYTNMRQITSEFEGKLNETQDYVQQLEMKNEDIG 1124

Query: 1811 AELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYF---------LRL 1659
             +L    +   Q++ E   +  +  +L  E E L    +E KDLE            ++ 
Sbjct: 1125 KQLEEARKFVSQLEGENGALMVKMRILEQEKEEL---CEEKKDLEKELYDEKSNFEEMKT 1181

Query: 1658 FEILLGQHVEVASLDIESCRFAEEKLMRIL-------DELICLRNENAKLKNEALYE-YH 1503
                L  ++E   + +E+ R  +EKL  +L       + L+   N+  +L  + L E   
Sbjct: 1182 VNSNLLINLEDLHILVEAVRSEKEKLNEVLMNERNESEALVTKLNDKCELLEDKLSECVD 1241

Query: 1502 DYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEED-SSGVDLLKNKCTRLEFQVQK 1326
            D E  N    R +    L+  +L N ++  +  +  ++   +  + L+    ++E Q+ +
Sbjct: 1242 DLESSNNELERVKEEKSLVETALENLKSEMQSIEKSQKVLENEKESLETTLKQVEVQLNE 1301

Query: 1325 L--------SEKAEMFETKSREAQQMANKLEEMQQTLSDM 1230
            L         E +E  ET ++E +++ +++E++ +   D+
Sbjct: 1302 LKNRNEVLEKEVSERTETSTKEKEELVSEVEKLSKINEDI 1341



 Score =  117 bits (293), Expect = 3e-23
 Identities = 174/884 (19%), Positives = 360/884 (40%), Gaps = 64/884 (7%)
 Frame = -3

Query: 3191 LQKKAGELQTKVHIREEE--SCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNALV 3018
            L+ K   L+TK+   EE   + +H  E L + +  + L++ +   E H+ Q ++Q+    
Sbjct: 465  LETKVVNLETKLQENEEVLGTVRHDKEELLSQV--TSLQAHIGQVEKHLSQALDQLEDYK 522

Query: 3017 KEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNALRQKNEDICL 2838
             + + LE      + +S+ L+   F+L +V  + E +K HT+      N L  +  ++ L
Sbjct: 523  LQSQTLEKQLTESKAVSEKLQ---FELADV--VLENQKTHTL-----LNDLYGEKNELVL 572

Query: 2837 KIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVL 2658
            K       LE+ +N    L   L E ++    L ++ +++   +   + E  E N QL++
Sbjct: 573  K-------LEEAENTKKSLEKHLFEFQDYSKNLASECETLRVENLAFKQELSEKNTQLLI 625

Query: 2657 LRDDVNHLKEALSMAVDDRAFMEK-------QLQDLENQKETVSKELALSVSREQKLASD 2499
            +  + + L   L         +EK       ++  L+NQ +     L  S S  QKL  D
Sbjct: 626  VTQEKSDLAIKLEYQDVKVVDLEKTNEGLNCEMDTLQNQLKETLDRLDSSQSYLQKLQLD 685

Query: 2498 LKALSEKEESTKNQL--------LIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEK 2343
               L  K    K QL         +  E+    E  +E+    LQ+++ E  +L +    
Sbjct: 686  YSELETKLNDAKTQLENLTVELNTVLEEKKSVAERLVEREDYVLQLEE-EKKILTEKTNV 744

Query: 2342 IYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKK------VNSDAG 2181
            + D  + L+ K  EVQ   E +LKQ  ++   L  +K+   S  ++KK        S   
Sbjct: 745  LEDSYRKLSQKCEEVQSYNEDVLKQLSDVSQSLEISKQEIGSLQELKKSLELQLEESQTS 804

Query: 2180 AKVSGI-LEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIR 2004
             +   + LE +      + SL +E    ++  + +++ +++ +E +Q   ++        
Sbjct: 805  LETLKVELEQMQSANVKINSLLQETEATLHQSKKESEDLKIQIETLQQELNDSINNLRES 864

Query: 2003 AQEVLRLQAEVDAIQHIL--IELKRKN-----QTLQDESQRNAKELWNAKARLNNVMSKN 1845
             ++V  LQ   + ++  L  +EL+ KN     + +  E   N KEL   K  L  +  ++
Sbjct: 865  QKDVFDLQESKNRVEENLKQVELESKNLKSELEKVHLEKSTNDKELSEVKKSLTELEEES 924

Query: 1844 IN-----------LESQNRSLKAELHLQAQKAFQIQEERNVVESE-------HNVLSSEV 1719
                         L+SQ       L    +K  ++Q  +N +E++          L  EV
Sbjct: 925  EKEKHHFETEIGVLQSQLNDALGSLETAKKKEEKLQNLKNQLETQLKETQAAEEKLKLEV 984

Query: 1718 ENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNEN 1539
            E L + L E++     FL+  E L  ++  +    ++  +  +E+L ++L +L     E+
Sbjct: 985  EKLSNNLSETRQERADFLKKLENLEDENGNL----LKESQELQERLSQVLSDLESKTAES 1040

Query: 1538 AKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKN 1359
             +L +         E +     +       I   L   ++N  E + ++       LL+N
Sbjct: 1041 KQLNDIQT----TLETRLDEAEKMRLQLETIQSHLDETQSNYEELKKEK------SLLEN 1090

Query: 1358 KCTRL-----EFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXI 1194
            + T +     EF+  KL+E  +  +    + + +  +LEE ++ +S +            
Sbjct: 1091 EYTNMRQITSEFE-GKLNETQDYVQQLEMKNEDIGKQLEEARKFVSQLEGENGALMVKMR 1149

Query: 1193 RVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXX 1014
             +   K+E    + +++ EL   +S      +    + I  ED   L++           
Sbjct: 1150 ILEQEKEELCEEKKDLEKELYDEKSNFEEMKTVNSNLLINLEDLHILVEAVRSEKEKLNE 1209

Query: 1013 KIDTRTSETQEIDTLMDDNRKYW-NRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXX 837
             +    +E++ + T ++D  +   +++S      +S  N ++ +++              
Sbjct: 1210 VLMNERNESEALVTKLNDKCELLEDKLSECVDDLESSNNELERVKEEKSLVETALENLKS 1269

Query: 836  KWGGIDMN---------SIEKQLKELNIHVMQLVEHNTRLKKDV 732
            +   I+ +         S+E  LK++ + + +L   N  L+K+V
Sbjct: 1270 EMQSIEKSQKVLENEKESLETTLKQVEVQLNELKNRNEVLEKEV 1313



 Score = 92.8 bits (229), Expect = 9e-16
 Identities = 155/733 (21%), Positives = 321/733 (43%), Gaps = 79/733 (10%)
 Frame = -3

Query: 3209 LEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQM 3030
            LE   A  K+  ++QT +  R +E+ K   +          LE+     ++H+ +     
Sbjct: 1033 LESKTAESKQLNDIQTTLETRLDEAEKMRLQ----------LETI----QSHLDETQSNY 1078

Query: 3029 NALVKEKRELENDAQRGEEISQSLK-------DEVFQLK----EVSRLYEEEKQHTIELQ 2883
              L KEK  LEN+     +I+   +       D V QL+    ++ +  EE ++   +L+
Sbjct: 1079 EELKKEKSLLENEYTNMRQITSEFEGKLNETQDYVQQLEMKNEDIGKQLEEARKFVSQLE 1138

Query: 2882 ENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHA 2703
                AL  K     +  +    L E+K ++  EL  +    EE ++   N + ++E +H 
Sbjct: 1139 GENGALMVKMR---ILEQEKEELCEEKKDLEKELYDEKSNFEEMKTVNSNLLINLEDLHI 1195

Query: 2702 VSQ---TEREELNRQLV-----------LLRDDVNHLKEALSMAVDDRAFMEKQLQDLEN 2565
            + +   +E+E+LN  L+            L D    L++ LS  VDD      +L+ ++ 
Sbjct: 1196 LVEAVRSEKEKLNEVLMNERNESEALVTKLNDKCELLEDKLSECVDDLESSNNELERVKE 1255

Query: 2564 QKETVSKELALSVSREQKLASDLKALSEKEES---TKNQLLIQTEQ----NKQLELEI-E 2409
            +K  V   L    S  Q +    K L  ++ES   T  Q+ +Q  +    N+ LE E+ E
Sbjct: 1256 EKSLVETALENLKSEMQSIEKSQKVLENEKESLETTLKQVEVQLNELKNRNEVLEKEVSE 1315

Query: 2408 KLYGSLQMKQ---MENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR 2238
            +   S + K+    E   L   NE I     +L    +E + ++E IL + +N    L+ 
Sbjct: 1316 RTETSTKEKEELVSEVEKLSKINEDIQHQLFILDRNYKESRSEKE-ILDKQLNEMSALSE 1374

Query: 2237 TKEVGRSATDMKKVNSDAGAKVSGILEMLLPM---KDDVFSL-----------KEEVLGN 2100
            T +    + +++     +  ++    +ML+ +   K+++F+L           ++++   
Sbjct: 1375 TLKA--ESENLRIQYQKSKIELEETRDMLMKLTSEKENLFTLLQHAKEQNGEFEKQISEM 1432

Query: 2099 INSLR---NDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKN 1929
            INSL    N    +  A++ ++D + +LF+E     Q +  ++ E    +   ++ + +N
Sbjct: 1433 INSLELKENKCNELNDAVKVLEDKQKDLFSENACLQQRLAVIEKENKERE---VKEREEN 1489

Query: 1928 QTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVE 1749
            + L  E +R ++E    +++L++   + ++LE+Q +    E  +Q  +   I   ++VV+
Sbjct: 1490 EQLSQELKRISQEKLLLESKLDD--DEVMSLETQKKIKSLEETIQDYE-ITISGLKSVVD 1546

Query: 1748 SEHNVLSSEVENLKSELKESKDLEGYFL-RLFEILLGQHV---EVASLDIESCRFAEEKL 1581
            +    L    E+LK EL + K  E   + +++++L   ++   E    D ++  F  E  
Sbjct: 1547 TNLESL----ESLKEELADQKIKESEIMTKIYDLLKDNNLIDDEDGQGDFKT--FITENF 1600

Query: 1580 MRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEA----------MSVLISKSLG 1431
             ++L      +N+  + + +   E  + + KN++ ++  A            VL    + 
Sbjct: 1601 EKLLSS----KNQEEQRRKDLKVEVEELKAKNMAATKLNANFQEMVEKLQTLVLEQSEVV 1656

Query: 1430 NGRANQREFQN-----------KEEDSSGVDLLKNKCTRLEFQVQK-LSEKAEMFETKSR 1287
               A +  F             K++ S  +D LKN  + L  ++   LSEK E+F++K+ 
Sbjct: 1657 TADALKASFDQIHSKVNSVLSLKQKLSEDLDQLKNDNSELSRKLDSVLSEKEEIFKSKTE 1716

Query: 1286 EAQQMANKLEEMQ 1248
              + +  + E+++
Sbjct: 1717 LEKNLKEEKEKVE 1729



 Score = 91.3 bits (225), Expect = 3e-15
 Identities = 183/909 (20%), Positives = 362/909 (39%), Gaps = 72/909 (7%)
 Frame = -3

Query: 3122 TEALENHIYGSLLESCVVDREAHIKQLMEQMNALVKEKRELEN---DAQRGEEISQSLKD 2952
            TE     +  S++E  + D +  I++L  Q+    +   +L N   + +     SQ L  
Sbjct: 369  TELCPEDLACSVIEVQLRDAQKQIEKLRTQIGETEECVTQLRNVLVETETKLRESQDLNT 428

Query: 2951 EVFQLKEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHK 2772
            E F  K  S   ++E   T +L    + L + N +I        N+LE K   +V L  K
Sbjct: 429  E-FDTKVKSLENDKETVQT-QLLSTQSVLDEANRNI--------NVLETK---VVNLETK 475

Query: 2771 LQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFM 2592
            LQENEE    +++D              +EEL  Q+  L+  +  +++ LS A+D     
Sbjct: 476  LQENEEVLGTVRHD--------------KEELLSQVTSLQAHIGQVEKHLSQALD----- 516

Query: 2591 EKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEEST----------KNQLLIQT 2442
              QL+D + Q +T+ K+L  S +  +KL  +L  +  + + T          KN+L+++ 
Sbjct: 517  --QLEDYKLQSQTLEKQLTESKAVSEKLQFELADVVLENQKTHTLLNDLYGEKNELVLKL 574

Query: 2441 EQNKQLELEIEK-----------LYGSLQMKQMENTLLK-DGNEKIYDLCKLLATKSR-- 2304
            E+ +  +  +EK           L    +  ++EN   K + +EK   L  +   KS   
Sbjct: 575  EEAENTKKSLEKHLFEFQDYSKNLASECETLRVENLAFKQELSEKNTQLLIVTQEKSDLA 634

Query: 2303 -----------EVQGQQEGILKQDINIEDELART------------------KEVGRSAT 2211
                       +++   EG+  +   ++++L  T                   E+     
Sbjct: 635  IKLEYQDVKVVDLEKTNEGLNCEMDTLQNQLKETLDRLDSSQSYLQKLQLDYSELETKLN 694

Query: 2210 DMKKVNSDAGAKVSGIL-------EMLLPMKDDVFSLKEE---VLGNINSLRNDAQMVQV 2061
            D K    +   +++ +L       E L+  +D V  L+EE   +    N L +  + +  
Sbjct: 695  DAKTQLENLTVELNTVLEEKKSVAERLVEREDYVLQLEEEKKILTEKTNVLEDSYRKLSQ 754

Query: 2060 ALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWN 1881
              E++Q    ++  +    +Q +   + E+ ++Q    ELK+  +   +ESQ + + L  
Sbjct: 755  KCEEVQSYNEDVLKQLSDVSQSLEISKQEIGSLQ----ELKKSLELQLEESQTSLETL-- 808

Query: 1880 AKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSE 1701
             K  L  + S N+ + S  +  +A LH   +++  ++ +   ++ E   L+  + NL+  
Sbjct: 809  -KVELEQMQSANVKINSLLQETEATLHQSKKESEDLKIQIETLQQE---LNDSINNLRES 864

Query: 1700 LKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNE 1521
             K+  DL+    R+ E L    +E  +L  E  +   EK      EL  ++    +L+ E
Sbjct: 865  QKDVFDLQESKNRVEENLKQVELESKNLKSELEKVHLEKSTND-KELSEVKKSLTELEEE 923

Query: 1520 ALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLE 1341
            +  E H +E +           + + +S  N      E   K+E+      L+N   +LE
Sbjct: 924  SEKEKHHFETE-----------IGVLQSQLNDALGSLETAKKKEEK-----LQNLKNQLE 967

Query: 1340 FQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTR 1161
             Q+ K ++ AE  E    E ++++N L E +Q  +D             ++ +L+ EN  
Sbjct: 968  TQL-KETQAAE--EKLKLEVEKLSNNLSETRQERADF----------LKKLENLEDENGN 1014

Query: 1160 LRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQ- 984
            L  E       S+  + R    + ++     +   L              ++TR  E + 
Sbjct: 1015 LLKE-------SQELQERLSQVLSDLESKTAESKQL--------NDIQTTLETRLDEAEK 1059

Query: 983  ---EIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMN 813
               +++T+     +  +      K+   L+N    ++Q                     +
Sbjct: 1060 MRLQLETIQSHLDETQSNYEELKKEKSLLENEYTNMRQI-------------------TS 1100

Query: 812  SIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQ-KLKV-DEEVPILCH 639
              E +L E   +V QL   N  + K ++    + + +   NG    K+++ ++E   LC 
Sbjct: 1101 EFEGKLNETQDYVQQLEMKNEDIGKQLEEARKFVSQLEGENGALMVKMRILEQEKEELCE 1160

Query: 638  QNSKIAERL 612
            +   + + L
Sbjct: 1161 EKKDLEKEL 1169



 Score = 72.4 bits (176), Expect = 1e-09
 Identities = 152/724 (20%), Positives = 306/724 (42%), Gaps = 107/724 (14%)
 Frame = -3

Query: 3089 LLESCVVDREAHIKQLMEQMNAL------------------VKEKRELENDAQRGEEISQ 2964
            +LE+     E  +KQ+  Q+N L                   KEK EL ++ ++  +I++
Sbjct: 1280 VLENEKESLETTLKQVEVQLNELKNRNEVLEKEVSERTETSTKEKEELVSEVEKLSKINE 1339

Query: 2963 SLKDEVF------------------QLKEVSRLYEEEKQHT-----------IELQENFN 2871
             ++ ++F                  QL E+S L E  K  +           IEL+E  +
Sbjct: 1340 DIQHQLFILDRNYKESRSEKEILDKQLNEMSALSETLKAESENLRIQYQKSKIELEETRD 1399

Query: 2870 AL-----------------RQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSA 2742
             L                 +++N +   +I    N LE K+N   EL+  ++  E+++  
Sbjct: 1400 MLMKLTSEKENLFTLLQHAKEQNGEFEKQISEMINSLELKENKCNELNDAVKVLEDKQKD 1459

Query: 2741 LQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQD---- 2574
            L ++   ++Q  AV + E +E   + V  R++   L + L     ++  +E +L D    
Sbjct: 1460 LFSENACLQQRLAVIEKENKE---REVKEREENEQLSQELKRISQEKLLLESKLDDDEVM 1516

Query: 2573 -LENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEI-EKLY 2400
             LE QK+   K L  ++   +   S LK++ +    +   L  +    K  E EI  K+Y
Sbjct: 1517 SLETQKKI--KSLEETIQDYEITISGLKSVVDTNLESLESLKEELADQKIKESEIMTKIY 1574

Query: 2399 GSLQMKQMENTLLKD----GNEKIY---DLCKLLATKSREVQGQQEGILKQDINIEDELA 2241
              L+    +N L+ D    G+ K +   +  KLL++K++E Q       ++D+ +E E  
Sbjct: 1575 DLLK----DNNLIDDEDGQGDFKTFITENFEKLLSSKNQEEQ------RRKDLKVEVEEL 1624

Query: 2240 RTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVF--SLK---EEVLGNINSLRNDA 2076
            + K +  +     K+N++    V  +  ++L   + V   +LK   +++   +NS+ +  
Sbjct: 1625 KAKNMAAT-----KLNANFQEMVEKLQTLVLEQSEVVTADALKASFDQIHSKVNSVLSLK 1679

Query: 2075 QMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNA 1896
            Q +   L+Q+++  SEL  + +    E   +      ++  L E K K + L  E +   
Sbjct: 1680 QKLSEDLDQLKNDNSELSRKLDSVLSEKEEIFKSKTELEKNLKEEKEKVENLHKELETKT 1739

Query: 1895 KELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVE 1716
            + +   K  +  V +K    +S+   LK E  L  +K    +  +N +E     L  E +
Sbjct: 1740 QPIKVQKENILGVSTK--GNKSREEELKKENMLLKRKVVLAENAKNNLEKVLKELREEKK 1797

Query: 1715 NLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAE---EKLMRILDELIC--- 1554
             ++ E+  S   +     L++ LL +++++   +    +  +   E+L R  +ELI    
Sbjct: 1798 KVR-EVPSSPTSDA----LYKKLLHEYIQIKEDNERVVKEKDAIIEELTRANEELIVKGA 1852

Query: 1553 -LRNENAKLKNEALYEYHD-YERKNVSGSRAEAMSVLISK-------SLGNGRANQREFQ 1401
             ++ E+ +   + L    + Y       S+ E   V + K        L N    +  ++
Sbjct: 1853 PIKQESGEKMVQDLQNIREAYGSVMSVNSKLEMEIVTLRKIIEERNGELANYSHIKEAYE 1912

Query: 1400 NKEEDS----SGVDLLKNKCTRLEFQVQKL--SEKAEMFETKSREAQQMAN----KLEEM 1251
               ED+    + +D +K K  R + +  +L   E+ E    ++++ Q + N    KLE+M
Sbjct: 1913 KLLEDNNKLMTEMDTIKYKRLRDKDEFVRLIKKERDENLNRETKKIQDIRNEYEGKLEKM 1972

Query: 1250 QQTL 1239
            ++ +
Sbjct: 1973 KEKM 1976



 Score = 65.5 bits (158), Expect = 1e-07
 Identities = 105/575 (18%), Positives = 235/575 (40%), Gaps = 48/575 (8%)
 Frame = -3

Query: 2813 LEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHL 2634
            L +KD II +L  +L+    +++ LQ +++   +     + + ++ N ++  LR +V  L
Sbjct: 184  LHEKDKIIAKLKSELEAERYEKADLQEELKIQLEKSKKVEQQLQQKNNEISRLRAEVGAL 243

Query: 2633 KEALS---MAVDDRAF----------MEKQLQDLENQKETVSKELALSVSREQKLASDLK 2493
            +         +D R            +E+ ++ +E++++ + KE   +  R +K+     
Sbjct: 244  ENRTPPHFQDMDSRELQRRLRSEIQTLEQYIKQIEDEQDEIRKEKDATKERLRKIEQQAS 303

Query: 2492 ALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSL-----------QMKQMENTLLKDGNE 2346
               EK   T+      TE +KQ E E+ +L               +  + +++L +   E
Sbjct: 304  MWEEKFFETERNFENLTEHSKQQEEELLQLQAHCAELTALLEEYREKPKNDSSLFEFSPE 363

Query: 2345 KIYD---------LCKLLATKSREVQGQQEGILKQDINIEDELARTK----EVGRSATDM 2205
            K  +          C ++  + R+ Q Q E +  Q    E+ + + +    E      + 
Sbjct: 364  KGLNKTELCPEDLACSVIEVQLRDAQKQIEKLRTQIGETEECVTQLRNVLVETETKLRES 423

Query: 2204 KKVNSDAGAKVSGILEMLLPMKDDVFSLK---EEVLGNINSLRNDAQMVQVALEQMQDTK 2034
            + +N++   KV  +      ++  + S +   +E   NIN L      ++  L++ ++  
Sbjct: 424  QDLNTEFDTKVKSLENDKETVQTQLLSTQSVLDEANRNINVLETKVVNLETKLQENEEVL 483

Query: 2033 SELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVM 1854
              +  + E    +V  LQA +  ++  L +   + +  + +SQ   K+L  +KA     +
Sbjct: 484  GTVRHDKEELLSQVTSLQAHIGQVEKHLSQALDQLEDYKLQSQTLEKQLTESKA-----V 538

Query: 1853 SKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEG 1674
            S+ +  E       A++ L+ QK   +  +    ++E  +   E EN K      K LE 
Sbjct: 539  SEKLQFE------LADVVLENQKTHTLLNDLYGEKNELVLKLEEAENTK------KSLEK 586

Query: 1673 YFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYE---YH 1503
            +     +       E  +L +E+  F +E L     +L+ +  E + L  +  Y+     
Sbjct: 587  HLFEFQDYSKNLASECETLRVENLAFKQE-LSEKNTQLLIVTQEKSDLAIKLEYQDVKVV 645

Query: 1502 DYERKNVS-GSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDL----LKNKCTRLEF 1338
            D E+ N       + +   + ++L    ++Q   Q  + D S ++      K +   L  
Sbjct: 646  DLEKTNEGLNCEMDTLQNQLKETLDRLDSSQSYLQKLQLDYSELETKLNDAKTQLENLTV 705

Query: 1337 QVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSD 1233
            ++  + E+ +    +  E +    +LEE ++ L++
Sbjct: 706  ELNTVLEEKKSVAERLVEREDYVLQLEEEKKILTE 740


>ref|XP_001027466.1| Viral A-type inclusion protein repeat containing protein [Tetrahymena
            thermophila] gi|89309236|gb|EAS07224.1| hypothetical
            protein TTHERM_01000170 [Tetrahymena thermophila SB210]
          Length = 1608

 Score =  127 bits (318), Expect = 4e-26
 Identities = 160/750 (21%), Positives = 334/750 (44%), Gaps = 34/750 (4%)
 Frame = -3

Query: 3227 AQHQKILED---YYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREA 3057
            A+ +KI+E+   Y  ++KK  ELQ K   +E+                 L++S   + + 
Sbjct: 214  AEVRKIIEEQEAYIVVEKK--ELQEKQQSQEK-----------------LIQSLQQEVKR 254

Query: 3056 HIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQEN 2877
            + + L+++ N L+K   +     +R + I +S+ D    LKE   + +  +Q  +   E 
Sbjct: 255  NEENLIQKTNELLKTVEDNNEWQERFQNIKKSVSDSDKLLKEQENIVKNLEQQLLNKSEQ 314

Query: 2876 FNALRQKNEDIC-----LKIEAN--NNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSV 2718
             N L Q+N+ +      LK +A+  N  ++  +  I EL+  +Q+ E ++   + + Q +
Sbjct: 315  INQLTQQNDQLSEALKKLKAQASNENQNIDHLNKKIEELNSLMQQKETEKEVAKEEKQQL 374

Query: 2717 EQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKEL 2538
                   Q + EE N+Q+  ++  + +L   L ++  +    E+ +Q+ +N +E      
Sbjct: 375  -------QLKTEEQNKQIAEMQVQIENLNSELKVSKQN---YEESMQNKQNSQEI----- 419

Query: 2537 ALSVSREQKLASDLKALSEKEESTKNQLLIQTE-QNKQLELEIEKLYGSLQMKQMENTLL 2361
                  E KL S+  AL E+ E+  N++  Q + Q  QL+ EI+K   SL+++Q++  L 
Sbjct: 420  ------EDKLESEKNALKEQLENKYNEICGQKDAQISQLQEEIQKY--SLEIQQLKEQLQ 471

Query: 2360 KDGNEK--IYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSD 2187
            +  N++  + D    L  +S E+   ++  L Q  N ++E+   K+  +  TD++    +
Sbjct: 472  QQINKEASLNDQISQLQKESEEIANLKQQ-LDQVQNKQNEILAQKQ--QEVTDLQNQLQE 528

Query: 2186 AGAKVSGILEMLLPMKDDVFSLKEEVLGNIN------SLRNDAQMVQVALEQMQDTKSEL 2025
              A+++   + LL  ++   SL +++   +N       L+N    +Q   ++    K  L
Sbjct: 529  MTAQINEGTKKLLDQENKNHSLSQQIQELVNVQQKNIELQNQIVQLQENEQKQGQEKHSL 588

Query: 2024 FAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKN 1845
              + E +  E+ + + ++  +Q    EL+ K Q L+D  + N   +   K +  N+ + +
Sbjct: 589  IQKNEHQVNEINQQKEQITKLQAEQRELEEKVQKLKDTIEENEDMINKLKQKEQNITNDS 648

Query: 1844 INLESQNRSLKAELHLQAQKAFQIQEERNVVESE-HNVLSSEVENLKSEL-KESKDLEGY 1671
             +L+   + L+ E+    + A +++E+ NV   E       +++ L+  L KE + +   
Sbjct: 649  SSLK---QKLEEEIEELKRHAHEVKEQFNVERGEIIEKHKQDIQKLQESLSKEGQGISDE 705

Query: 1670 FLRLFE---------ILLGQHVEVASLDIESCRFAEEKLMRILDELI----CLRNENAKL 1530
              +L E           L Q+++    DI++     +K+M+ L+E I     L++   KL
Sbjct: 706  IAKLNEERTKLSDENFELKQNIKDHQKDIQAKEEEIKKIMKNLEEQIQQFNNLKDSYNKL 765

Query: 1529 KNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCT 1350
            + E+     D+E++         M  L SK                     ++ L+N   
Sbjct: 766  EEESNKSKKDFEKR---------MEKLSSKK-----------------KEALEKLENNIK 799

Query: 1349 RLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKE 1170
             L  QVQ+  E  +  ET+  E ++   +L++   T S +            ++  +K+E
Sbjct: 800  ELNIQVQQKDEAIQKLETEKTETEKKYQQLKKDSSTQSSI------QEELNAQINQIKQE 853

Query: 1169 NTRLRSEMKGELTPSRSFKHREGSFIKEIN 1080
               +  +++ E   +   K    + IK++N
Sbjct: 854  YELISQKLQSE---NNELKQNHEAQIKKLN 880



 Score = 99.8 bits (247), Expect = 7e-18
 Identities = 150/705 (21%), Positives = 302/705 (42%), Gaps = 58/705 (8%)
 Frame = -3

Query: 3170 LQTKVHIRE-EESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNALVKEKRELEN 2994
            +Q K + +E E+  +    AL+  +     E C   ++A I QL E++     E ++L+ 
Sbjct: 410  MQNKQNSQEIEDKLESEKNALKEQLENKYNEICG-QKDAQISQLQEEIQKYSLEIQQLKE 468

Query: 2993 DAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNA-LRQKNEDICLKIEANNN 2817
              Q+      SL D++ QL++ S      KQ   ++Q   N  L QK +++        N
Sbjct: 469  QLQQQINKEASLNDQISQLQKESEEIANLKQQLDQVQNKQNEILAQKQQEVT----DLQN 524

Query: 2816 LLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNH 2637
             L++    I E + KL + E +  +L   +Q +  +    Q +  EL  Q+V L+++   
Sbjct: 525  QLQEMTAQINEGTKKLLDQENKNHSLSQQIQELVNV----QQKNIELQNQIVQLQENEQK 580

Query: 2636 LKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQ 2457
              +     +      E Q+ ++  QKE ++K  A     E+K+   LK   E+ E   N+
Sbjct: 581  QGQEKHSLIQKN---EHQVNEINQQKEQITKLQAEQRELEEKVQK-LKDTIEENEDMINK 636

Query: 2456 LLIQTEQN---------KQLELEIEKLYGSL-QMKQMENTLLKDGNEKIYDLCKLLATKS 2307
            L  Q EQN         ++LE EIE+L     ++K+  N           +  +++    
Sbjct: 637  LK-QKEQNITNDSSSLKQKLEEEIEELKRHAHEVKEQFNV----------ERGEIIEKHK 685

Query: 2306 REVQGQQEGILKQDINIEDELARTKEVGRSATD--------MKKVNSDAGAKVSGILEML 2151
            +++Q  QE + K+   I DE+A+  E     +D        +K    D  AK   I +++
Sbjct: 686  QDIQKLQESLSKEGQGISDEIAKLNEERTKLSDENFELKQNIKDHQKDIQAKEEEIKKIM 745

Query: 2150 LPMKDDV--FSLKEEVLGNINSLRNDAQM-VQVALEQMQDTKSELFAEAEIRAQEV-LRL 1983
              +++ +  F+  ++    +    N ++   +  +E++   K E   + E   +E+ +++
Sbjct: 746  KNLEEQIQQFNNLKDSYNKLEEESNKSKKDFEKRMEKLSSKKKEALEKLENNIKELNIQV 805

Query: 1982 QAEVDAIQHI---LIELKRKNQTLQDESQRNAKELWNAKARLNNVMSK----NINLESQN 1824
            Q + +AIQ +     E ++K Q L+ +S   +       A++N +  +    +  L+S+N
Sbjct: 806  QQKDEAIQKLETEKTETEKKYQQLKKDSSTQSSIQEELNAQINQIKQEYELISQKLQSEN 865

Query: 1823 RSLKAELHLQAQK--AFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEI 1650
              LK     Q +K  A QI+E +N+ +        + E LK  L + +      +++ E 
Sbjct: 866  NELKQNHEAQIKKLNADQIEEVQNLKDQ----FQQQTEQLKQNLSQQEQELTQQIKIKE- 920

Query: 1649 LLGQHVEVASLDIESCRFAEEKLMRIL--DELICLRNENAKLKNEALYEYHDYERKNVSG 1476
                  E  ++ +E  ++      RIL  + +  L+ E+ + +++        + K    
Sbjct: 921  ------EEYNVKLEDEKYITVDNNRILVREYIQQLQCESEQKRDQIKQLEQQLQEKKDQI 974

Query: 1475 SRAEAMSVLISKSLGN----------GRANQREFQNKE--EDSSGVDLLKNKCTRLEFQV 1332
            S  E    L+ + +             + NQ+E QN    +    + LL+ + ++ E Q+
Sbjct: 975  SNLETQIPLLKQKIEQLECELNSHLTEKQNQQESQNSSLSQKDEAIKLLQTQISQQEEQL 1034

Query: 1331 QKL-----------SEKAEMFETKSREAQQMANKLEEMQQTLSDM 1230
            ++L           SEK     + + +      KLEE+Q+   ++
Sbjct: 1035 KELIQHKEDNLQSHSEKDSQINSLTSQISDQVLKLEELQKQKDEL 1079



 Score = 76.3 bits (186), Expect = 8e-11
 Identities = 146/706 (20%), Positives = 293/706 (41%), Gaps = 83/706 (11%)
 Frame = -3

Query: 3191 LQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNALVKE 3012
            L ++  EL  ++ I+EEE        LE+  Y ++  + ++ RE +I+QL  +      +
Sbjct: 905  LSQQEQELTQQIKIKEEE----YNVKLEDEKYITVDNNRILVRE-YIQQLQCESEQKRDQ 959

Query: 3011 KRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNALRQKNEDICLKI 2832
             ++LE   Q  ++   +L+ ++  LK+        K   +E + N +   ++N+      
Sbjct: 960  IKQLEQQLQEKKDQISNLETQIPLLKQ--------KIEQLECELNSHLTEKQNQQ----- 1006

Query: 2831 EANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQL---V 2661
            E+ N+ L QKD  I  L  ++ + EEQ   L    +   Q H+   ++   L  Q+   V
Sbjct: 1007 ESQNSSLSQKDEAIKLLQTQISQQEEQLKELIQHKEDNLQSHSEKDSQINSLTSQISDQV 1066

Query: 2660 LLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSE 2481
            L  +++   K+ L    D+    EK+ Q  E+Q + + +   L    +Q+L+   K + E
Sbjct: 1067 LKLEELQKQKDELQREKDELQ-KEKESQQQESQNQLIQEITLL----KQQLSDSQKQIEE 1121

Query: 2480 KEESTKNQLLIQTEQNKQLELEIEKLYG--SLQMKQMENTLLKDGNEKIYDLCKLLATKS 2307
             E+    Q+   ++++K +   +++ Y     + KQ+E+ L++   +   +  +L     
Sbjct: 1122 NEK----QIAQISQEHKTVVDGLQESYNRKEKEAKQLEDQLIRIQQQHQEEQAELQKKSQ 1177

Query: 2306 REVQGQQEGILKQDINIEDELARTKEV------GRSATDMKKVNSDAGAKVSGILEMLLP 2145
             +     +   K   NIE      +E+        SA   +  N++  ++V+ I E +  
Sbjct: 1178 LDSSNMVKLNEKNQKNIEALKRGNRELINMIIDSYSALSNQLDNANIQSQVNAITECIKN 1237

Query: 2144 MKDDVFS------------LKEEVLGNINSLRN-DAQMVQVALEQMQDTKSEL-FAEAEI 2007
               D+              + E     IN+++N + Q     LEQ   ++ ++    ++I
Sbjct: 1238 TSPDIMKEFQKFLLESRNLISEHYQNQINNVKNQEKQRYNKLLEQFNKSQDDIKQLNSKI 1297

Query: 2006 RAQEVLRLQ----AEVDAIQHILIELKR---KNQTLQDESQRNAK--ELWNAKARLNNVM 1854
            +A E L  Q    +++ A+Q   I+ K    K+  ++  S    K  EL N + ++  + 
Sbjct: 1298 KAAEKLERQVQEYSDIIALQKQTIQKKEAAFKDLQIEISSSDADKRTELANLQEKVQLLK 1357

Query: 1853 SKNINLESQN-----------------RSLKAELHLQAQKA----FQIQEERNVVESEHN 1737
             KN  L S+N                    KA+L  +A +       IQE+ + +++   
Sbjct: 1358 QKNEQLISENTAQKELNAKILHDIQDLEQSKAQLEEKANQGSDLIMLIQEKDSQIQALEE 1417

Query: 1736 VLSS---------------------EVENLKSELKESKDLEGYFLRLFEILLGQHVEVAS 1620
             LSS                     E++ +++EL +SK+     + L + L  Q  ++ S
Sbjct: 1418 SLSSLQTIHEDFQKRNEQLAKKYDFELKKIRTELAQSKEK----IALVDELTAQIAQLES 1473

Query: 1619 LDIE---SCRFAEEKLMRILDELICLRNEN----AKLKNEALYEYHDYERKNVSGSRAEA 1461
               E        +EK      E   ++NE      KLK++A+   +  +R+ +S      
Sbjct: 1474 AFNEKNQKYNTLQEKYAESEKERALIKNETNQLLNKLKSDAVKSEYQIDRRVISN----- 1528

Query: 1460 MSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKL 1323
                + +      +NQ + Q  E  SS +   + +  ++  Q QKL
Sbjct: 1529 ---FLVQYFDTNSSNQVKLQILETMSSILQFNEEQKAKIGIQKQKL 1571


>ref|XP_001323236.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
            gi|121906097|gb|EAY11013.1| viral A-type inclusion
            protein, putative [Trichomonas vaginalis G3]
          Length = 2458

 Score =  126 bits (316), Expect = 7e-26
 Identities = 196/906 (21%), Positives = 365/906 (40%), Gaps = 43/906 (4%)
 Frame = -3

Query: 3092 SLLESCVVDREAHIKQLMEQMNALVKEKRELENDAQRGEEIS-QSLKDEVFQLKEV---- 2928
            S L+  VV  +  I Q  +++N L     +L+N     + +  +  K ++ + +++    
Sbjct: 278  SRLKKAVVQLKKQIAQKDQEINDLKTSNMQLQNFNNETQNVEIEKYKSQIIEFQKIIESL 337

Query: 2927 ----SRLYEEEKQHTIELQENFNALRQKNEDICLKIEAN------NNLLEQKDNIIVELS 2778
                ++L  E      +LQ     L+Q+N ++  +I+ N      NN  E+  N I EL 
Sbjct: 338  KAENAKLQTENTNTVDKLQSEIEKLKQENSELQNQIQENEDGWNDNNNEEELQNQITELQ 397

Query: 2777 HKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRA 2598
             +L+EN++  S      +  EQ+  +   + ++           +  LK+ L+ A D   
Sbjct: 398  KQLEENKKSYS------EETEQLKQIIDDDSKQ-----------IEDLKQKLAEAQDHEG 440

Query: 2597 FMEKQLQDLENQKETVSKELA--LSVSREQKLASD-----LKALSEKEESTKNQ---LLI 2448
              + QL  L+ +K+ + K+L    +  R+ K  +D     +  L+E+  S + Q   L  
Sbjct: 441  NSDSQLAKLQTEKQQLDKKLVDVANALRKLKTKNDNDQATISKLNEENSSLQKQIEELKQ 500

Query: 2447 QTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQ 2268
            QT  N   E EI+ L   LQ  Q++N  +K  NE +         KS E++ Q++ I + 
Sbjct: 501  QTANNASYEAEIQNLKKQLQDLQIQNDDIKTENEHLQQEM-FENNKSEEIEQQKKQISEL 559

Query: 2267 DINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSL 2088
                       KE+   +++++  N +    +  + + +  +K +   L EE+  N  + 
Sbjct: 560  Q----------KEISSKSSEIQAKNDE----IENLNKEIEQIKKENQELNEELFQNNENN 605

Query: 2087 RNDAQM--VQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQD 1914
             ND ++  ++  ++ +Q   S+L  +      +V  L+ E++           K+Q+ QD
Sbjct: 606  SNDEEIEKLKTQIQSLQKEISDLSQQNNNYKSQVEELKEELE-----------KHQSEQD 654

Query: 1913 ESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVV-ESEHN 1737
            E+       W  +     + S+N NL+ Q   LK +L+   QK  Q QEE     E+E  
Sbjct: 655  ENG------WGEENESEELKSENENLKKQIEELKEQLN---QKEDQGQEENGWCNENETE 705

Query: 1736 VLSSEVENLKSE---LKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILD 1566
             L SE+E LK E   LK++ + E    ++ E+      +      E+    E +      
Sbjct: 706  DLKSEIEQLKKENETLKQNNETESLKKQIEELKEQLKQKEDQGQEENGWGEENETEDYKS 765

Query: 1565 ELICLRNE----NAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQN 1398
            ++  L NE    N K+K+ A              S+ E +   + ++  NG  +     N
Sbjct: 766  QISALENEKRTLNKKIKDLA-------NGLKTLKSKNEKLEQQLKENANNGNND-----N 813

Query: 1397 KEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXX 1218
             ++ S   +  + K T LEF+ ++L    E    + +   +  NKL    +TLSD     
Sbjct: 814  SKDISVEFNETEEKITELEFENEELRRNNESLSEEKKTLHKQNNKLVSENKTLSD----- 868

Query: 1217 XXXXXXXIRVRSLKKENTRLRSEMKGELTPSRS---FKHREGSFIKEINIGDEDDTPLIQ 1047
                    +V  L++E     +E++ E+   RS    + +E    K  N    ++     
Sbjct: 869  -EVSTLREQVEELEEETISTSNELRSEIEHLRSELVVREQELEQTKNNNNNVNNNENNNS 927

Query: 1046 XXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXX 867
                       KI     + +E+      N    N      K+  SL+  +++L+Q    
Sbjct: 928  NVHSDQSIYEEKISLLKQQLEELKQSQSSN----NNNEELEKENISLKKEIEDLKQ---- 979

Query: 866  XXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNG 687
                       + G + N    Q KE  IH  +L      LKK  K   +  N   + NG
Sbjct: 980  --ENEGLQNQLFEGGETNENNNQEKEDEIH--KLKSEIEELKK--KLESSEQNKEEENNG 1033

Query: 686  QEQKLKVDEEVPILCHQ----NSKIAERLDINTDKARAL-DMEVQRIRLILSRIPTKPTE 522
               +    E +  L  +    N K+ E +  N +K + + +M+ +   L          E
Sbjct: 1034 WGDENTETENIDNLKSEIEELNKKLDESIKSNDEKQKKIEEMKQENEELQTQLFENNSEE 1093

Query: 521  EASKMR 504
            E +K +
Sbjct: 1094 EINKFK 1099



 Score =  124 bits (310), Expect = 3e-25
 Identities = 196/954 (20%), Positives = 401/954 (42%), Gaps = 124/954 (12%)
 Frame = -3

Query: 3224 QHQKILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQ 3045
            Q+ K++ +   L  +   L+ +V   EEE+     E L + I    L S +V RE  ++Q
Sbjct: 855  QNNKLVSENKTLSDEVSTLREQVEELEEETISTSNE-LRSEI--EHLRSELVVREQELEQ 911

Query: 3044 LMEQMNALVKEKRELEN---DAQRGEEISQSLKDEVFQLKEV---SRLYEEEKQHTIELQ 2883
                 N +   +    N   D    EE    LK ++ +LK+    +   EE ++  I L+
Sbjct: 912  TKNNNNNVNNNENNNSNVHSDQSIYEEKISLLKQQLEELKQSQSSNNNNEELEKENISLK 971

Query: 2882 ENFNALRQKNEDICLKI----EANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVE 2715
            +    L+Q+NE +  ++    E N N  ++K++ I +L  +++E +++  + + + +   
Sbjct: 972  KEIEDLKQENEGLQNQLFEGGETNENNNQEKEDEIHKLKSEIEELKKKLESSEQNKEEEN 1031

Query: 2714 QMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELA 2535
                   TE E ++     L+ ++  L + L  ++      +K++++++ + E +  +L 
Sbjct: 1032 NGWGDENTETENIDN----LKSEIEELNKKLDESIKSNDEKQKKIEEMKQENEELQTQLF 1087

Query: 2534 LSVSREQ--KLASDLKALSEK--EESTKNQ-LLIQTEQN--------KQLELEIEKLY-- 2400
             + S E+  K  S ++ L++K  E + KN+ L  QTE+         KQ E E EKL   
Sbjct: 1088 ENNSEEEINKFKSQVEELTQKLQESNQKNEELQSQTEKQNNEIDDLKKQKEEENEKLQKE 1147

Query: 2399 --------GSLQMKQMEN--------TLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQ 2268
                      LQ K+ EN         +LK  NEK  +  + LA +  E+Q ++E   KQ
Sbjct: 1148 ISDLKNEISQLQQKEEENGSDLQKQIEVLKQTNEKNDEDIEQLAKQIDELQTEKE---KQ 1204

Query: 2267 DINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSL--KEEVLGNIN 2094
            +  I D  ++ + V    +++K  N     ++  + +    ++  +F +   +E    I+
Sbjct: 1205 NEEINDLKSQLQNV----SEIKSENEKQKNEIDDLKKENEELQTQLFEIGNNQEKEEEIH 1260

Query: 2093 SLRNDAQMVQVALEQMQDTKSE-----LFAEAEIRAQEVLRLQAEVDAIQHILIELKRKN 1929
             L+++ + ++  LE+ +  K E     L +E E   +E+ RL+++ + ++    EL+++N
Sbjct: 1261 KLKSEIEELKKKLEESEQNKEEENIDNLKSENETLKEEIKRLESDNEQLKKQNSELQQEN 1320

Query: 1928 QTL-QDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEER--- 1761
            ++L Q +S+   +  W  +     + S+N +L+ Q   LK +L    QK  Q QEE    
Sbjct: 1321 KSLHQQQSKEEEENGWGEENESEELKSENESLKKQIEELKEQLK---QKEDQGQEENGWG 1377

Query: 1760 ------------NVVESEHNVLSSEVENLKSELKESKDL-EGYFLRLFEILLGQHVEVAS 1620
                        + +E+E   L+ ++++L + LK  K   E    +L +I         S
Sbjct: 1378 DENETEDYKSQISALENEKRTLNKKIKDLANGLKTLKSKNEKLEQQLKDINSNNSTNDNS 1437

Query: 1619 LDIE-----------SCRFAEEKLMR----ILDELICLRNENAKL--KNEALYEYHDYER 1491
             DI               F  E+L R    + +E   L+ +N KL  +N+ L +     R
Sbjct: 1438 KDISVEFNETEEKITELEFENEELRRNNESLSEEKKTLQKQNNKLVSENKTLSDEVSTLR 1497

Query: 1490 KNVSGSRAEAMS----------------VLISKSLGNGRANQREFQNKEEDSSGV----D 1371
            + V     E +S                VL  + L   + N     N E ++S V     
Sbjct: 1498 EQVEELEEETISTSNELRSEIEHLRSELVLREQELEQTKNNNNNVNNNENNNSNVHSDQS 1557

Query: 1370 LLKNKCTRLEFQVQKLSEKAEM-FETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXI 1194
            + + K + L+ Q+++L ++ +  F+ +        NKL++                    
Sbjct: 1558 IYEEKISLLKQQLEELKQQQQKPFDHEDNNDSDEINKLKK-------------------- 1597

Query: 1193 RVRSLKKENTRLRSEM-KGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXX 1017
             +  LK+EN  L++++ +G  T   + + +E   I ++    E+    ++          
Sbjct: 1598 EIEDLKQENEELQNQLFEGGETNENNNQEKEDE-IHKLKSEIEELKKKLESSEQNKEEEN 1656

Query: 1016 XKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXX 837
                   +ET+ I+ L  +  +   +++  +K     Q  ++EL+Q              
Sbjct: 1657 NGWGDENTETENIENLKSEIEELNKKLNELSKSNDEKQKKIEELEQKLQESQNNKDEEEE 1716

Query: 836  KWGGI--------------------DMNSIEKQLKELNIHVMQLVEHNTRLKKD 735
                +                    ++ +++KQ++E    + ++ E   +L+KD
Sbjct: 1717 NIEDLKEQLEQLRRDAITKSKQDQEEIENLKKQIEEKEADIEEITEELEQLRKD 1770



 Score =  116 bits (290), Expect = 7e-23
 Identities = 159/804 (19%), Positives = 351/804 (43%), Gaps = 44/804 (5%)
 Frame = -3

Query: 3185 KKAGELQTKVHIREEESCKHLTEALENHI------YGSLLESCVVDREAHIKQLMEQMNA 3024
            K   E Q K+   ++E+ +  T+  EN+       + S +E      +   ++  E  + 
Sbjct: 1063 KSNDEKQKKIEEMKQENEELQTQLFENNSEEEINKFKSQVEELTQKLQESNQKNEELQSQ 1122

Query: 3023 LVKEKRELENDAQRGEEISQSLKDEVFQLK-EVSRLYEEEKQHTIELQENFNALRQKNED 2847
              K+  E+++  ++ EE ++ L+ E+  LK E+S+L ++E+++  +LQ+    L+Q NE 
Sbjct: 1123 TEKQNNEIDDLKKQKEEENEKLQKEISDLKNEISQLQQKEEENGSDLQKQIEVLKQTNEK 1182

Query: 2846 ICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQ 2667
                   N+  +EQ    I EL  + ++  E+ + L++ +Q+V ++ + ++ ++ E+   
Sbjct: 1183 -------NDEDIEQLAKQIDELQTEKEKQNEEINDLKSQLQNVSEIKSENEKQKNEI--- 1232

Query: 2666 LVLLRDDVNHLKEALS---MAVDDRAFMEKQLQDLENQKETVSKELALS-VSREQKLASD 2499
                 DD+    E L      + +    E+++  L+++ E + K+L  S  ++E++   +
Sbjct: 1233 -----DDLKKENEELQTQLFEIGNNQEKEEEIHKLKSEIEELKKKLEESEQNKEEENIDN 1287

Query: 2498 LKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQM------------ENTLLKD 2355
            LK+ +E  +    +L    EQ K+   E+++   SL  +Q             E+  LK 
Sbjct: 1288 LKSENETLKEEIKRLESDNEQLKKQNSELQQENKSLHQQQSKEEEENGWGEENESEELKS 1347

Query: 2354 GNEKIYDLCKLL--ATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAG 2181
             NE +    + L    K +E QGQ+E     +   ED  ++   +      + K      
Sbjct: 1348 ENESLKKQIEELKEQLKQKEDQGQEENGWGDENETEDYKSQISALENEKRTLNK------ 1401

Query: 2180 AKVSGILEMLLPMKDDVFSLKEEV--LGNINSLRNDAQMVQVALEQMQDTKSELFAEAEI 2007
             K+  +   L  +K     L++++  + + NS  ++++ + V   + ++  +EL  E E 
Sbjct: 1402 -KIKDLANGLKTLKSKNEKLEQQLKDINSNNSTNDNSKDISVEFNETEEKITELEFENEE 1460

Query: 2006 RAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQ 1827
              +    L  E   +Q    +L  +N+TL DE     +++   +      +S +  L S+
Sbjct: 1461 LRRNNESLSEEKKTLQKQNNKLVSENKTLSDEVSTLREQVEELE---EETISTSNELRSE 1517

Query: 1826 NRSLKAELHLQAQKAFQIQEERN----------VVESEHNVLSSEVENLKSELKESKDLE 1677
               L++EL L+ Q+  Q +   N           V S+ ++   ++  LK +L+E K   
Sbjct: 1518 IEHLRSELVLREQELEQTKNNNNNVNNNENNNSNVHSDQSIYEEKISLLKQQLEELK--- 1574

Query: 1676 GYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDY 1497
                           +    D E    ++E + ++  E+  L+ EN +L+N+ L+E  + 
Sbjct: 1575 -------------QQQQKPFDHEDNNDSDE-INKLKKEIEDLKQENEELQNQ-LFEGGET 1619

Query: 1496 ERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSG-------VDLLKNKCTRLEF 1338
               N +  + + +  L S+     +  +   QNKEE+++G        + ++N  + +E 
Sbjct: 1620 NENN-NQEKEDEIHKLKSEIEELKKKLESSEQNKEEENNGWGDENTETENIENLKSEIEE 1678

Query: 1337 QVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRL 1158
              +KL+E ++  + K ++ +++  KL+E Q    +              +  LK++  +L
Sbjct: 1679 LNKKLNELSKSNDEKQKKIEELEQKLQESQNNKDE----------EEENIEDLKEQLEQL 1728

Query: 1157 RSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEI 978
            R   +  +T S+  +    +  K+I   +E +  + +            I     + +EI
Sbjct: 1729 R---RDAITKSKQDQEEIENLKKQI---EEKEADIEEITEELEQLRKDSITKAKQDQEEI 1782

Query: 977  DTLMDDNRKYWNRVSHFTKQTQSL 906
            + L ++ +K    + +   +   L
Sbjct: 1783 EKLQNEIQKQKEIIDNLNAEIDEL 1806



 Score = 90.1 bits (222), Expect = 6e-15
 Identities = 151/728 (20%), Positives = 308/728 (42%), Gaps = 85/728 (11%)
 Frame = -3

Query: 3188 QKKAGELQTKVHI------REEESCKHLTEALENHIYGSL------------LESCVVDR 3063
            QKK  EL+ K+         EEE+ + L E LE     ++            L+  + ++
Sbjct: 1694 QKKIEELEQKLQESQNNKDEEEENIEDLKEQLEQLRRDAITKSKQDQEEIENLKKQIEEK 1753

Query: 3062 EAHIKQLMEQMNALVKEK-----------RELENDAQRGEEISQSLKDEVFQLKEVSRLY 2916
            EA I+++ E++  L K+             +L+N+ Q+ +EI  +L  E+ +L E    +
Sbjct: 1754 EADIEEITEELEQLRKDSITKAKQDQEEIEKLQNEIQKQKEIIDNLNAEIDELGEKEAEH 1813

Query: 2915 EEEKQHTIELQEN--------------FNA--------LRQKNEDICLKIEANNNLLEQK 2802
            E+ K    +L+++               NA        L    E+I    + N    E  
Sbjct: 1814 EDLKDELQQLRKDSLQKAKIDQAEIDRLNAEVSNLKFELENGKENIWGDDDDNEKHKETL 1873

Query: 2801 DNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTER---EEL------NRQLVLLRD 2649
              II +L  ++++   +   L+ ++   E    V Q  +   EEL      N +L  + +
Sbjct: 1874 TEIIEKLKSEIEDKNSEIEKLEEEISQFEDPTEVKQENKKLKEELDQALRQNAELGNVNE 1933

Query: 2648 DVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALS-EKEE 2472
            + N L+E L  ++D             N+ +T+ K+L       QKL  DL  L  E   
Sbjct: 1934 ENNKLREQLKQSIDT------------NELKTLEKKLKEKEEENQKLHDDLNTLQFELNN 1981

Query: 2471 STKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQG 2292
            S      I   ++ ++  E+E+L                 N+K+ +L K L  +   +  
Sbjct: 1982 SIAGLPKINQSESMEIRDEVERLANE--------------NKKLSELTKKLEEEKNFLVS 2027

Query: 2291 QQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEE 2112
            Q E +++++ + E EL   +E+      +KK   D         E LL   D++    E 
Sbjct: 2028 QLENVVQRN-DYEKELQNVEEL---KLKLKKAEKDN--------EELLQQIDELVEQNET 2075

Query: 2111 VLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRK 1932
                 +   ++ + ++  L +++D++ E     ++  +EV  L  +++  + I  ELK  
Sbjct: 2076 ENHEKSDAESELKSLKAELAKLKDSEKEY----QVLREEVDELTQKIEESETINKELK-- 2129

Query: 1931 NQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVV 1752
              T+ D++  +A E    KA+ + + +   +L+SQN  LK +     Q+  ++ EE+  +
Sbjct: 2130 --TIIDQNDTSAAENMY-KAQFDELKALVSDLKSQNEDLKKDSENSKQEITKLTEEKTEL 2186

Query: 1751 ES-------EHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFA 1593
             +       +++ LSS VE L +E+   K    +     E ++     VA+ +++    A
Sbjct: 2187 NANIEKLTQDNSNLSSNVEKLTNEISNLK----FQPTAQENVVPAETPVAN-EVKPSEEA 2241

Query: 1592 -----EEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISK---S 1437
                 E++  ++  E   L  +N ++  + +   ++ E++N   ++ +   +  ++   S
Sbjct: 2242 VSTPNEDEKAKLESEKEELVKKNDEMMKQIVLMKNEIEKQNKEFAQMQERFIKANEENMS 2301

Query: 1436 LGNGRANQREFQNK-EEDSSGVDLLKNKCTRLEFQVQ-----KLSEKAEMF---ETKSRE 1284
            L N  +  +E + + ++ ++ V  L+     L+ + Q     KL++ A+ F     K R 
Sbjct: 2302 LRNVASKNKELETQLDQKTANVLSLRKDIDNLKIEFQKDLDAKLAKAAKEFNDLRKKFRV 2361

Query: 1283 AQQMANKL 1260
             +Q  N+L
Sbjct: 2362 VEQQRNQL 2369



 Score = 79.0 bits (193), Expect = 1e-11
 Identities = 158/816 (19%), Positives = 327/816 (40%), Gaps = 59/816 (7%)
 Frame = -3

Query: 2726 QSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVS 2547
            +S+ + + + +  + E   Q+    D +   +E  +   ++ A  +K++++ E   E ++
Sbjct: 27   KSLSKENDILKRTQAEYQAQIQKCSDALIEERETTATLTNELAECDKKIEEKEKLIEDLA 86

Query: 2546 KELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENT 2367
            KE+                     E+ KN     ++ +  LE  +++    ++  + EN 
Sbjct: 87   KEI---------------------ENMKNTTSTASQNDSGLEEVVQEFEQKIETLESENK 125

Query: 2366 LLKDGNEKIY-------DLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATD 2208
             +KD N ++        +L   L+T+S E+Q + E I  +D + E+ L +T         
Sbjct: 126  TMKDQNSELQQQIQQYKELTDKLSTESTELQQKMENIKSEDKSAEETLLQT--------- 176

Query: 2207 MKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSE 2028
                 SD   +++ + E L   K    S ++    N N+    AQ  Q    Q+ D K++
Sbjct: 177  ----ISDQDIQINKLKEELEQAKLAANSSEQ----NTNAF---AQKEQELNAQITDLKNQ 225

Query: 2027 LFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSK 1848
            L A+  + + E+  L+A++  +     +   +N+ L+ ESQ++A               K
Sbjct: 226  LAAKDSL-SDEIASLKAQIAELNQNNSKSSEENEQLKAESQKDASS-----------DDK 273

Query: 1847 NINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNV--LSSEVENLKSELKESKDLEG 1674
            N +L   +R  KA + L+ Q A + QE  ++  S   +   ++E +N++ E  +S+ +E 
Sbjct: 274  NSDL---SRLKKAVVQLKKQIAQKDQEINDLKTSNMQLQNFNNETQNVEIEKYKSQIIE- 329

Query: 1673 YFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYE 1494
             F ++ E L     E A L  E+    +    ++  E+  L+ EN++L+N+ + E  D  
Sbjct: 330  -FQKIIESL---KAENAKLQTENTNTVD----KLQSEIEKLKQENSELQNQ-IQENEDGW 380

Query: 1493 RKNVSGSRAEAMSVLISKSLGNGRANQREFQNK-----EEDSSGVDLLKNK--------- 1356
              N +    +     + K L   + +  E   +     ++DS  ++ LK K         
Sbjct: 381  NDNNNEEELQNQITELQKQLEENKKSYSEETEQLKQIIDDDSKQIEDLKQKLAEAQDHEG 440

Query: 1355 -----CTRLEFQVQKLSEK-------AEMFETKSREAQQMANKLEE----MQQTLSDMXX 1224
                   +L+ + Q+L +K           +TK+   Q   +KL E    +Q+ + ++  
Sbjct: 441  NSDSQLAKLQTEKQQLDKKLVDVANALRKLKTKNDNDQATISKLNEENSSLQKQIEELKQ 500

Query: 1223 XXXXXXXXXIRVRSLKK--------------ENTRLRSEMKGELTPSRSFKHREGSFIKE 1086
                       +++LKK              EN  L+ EM  E   S   + ++   I E
Sbjct: 501  QTANNASYEAEIQNLKKQLQDLQIQNDDIKTENEHLQQEM-FENNKSEEIEQQKKQ-ISE 558

Query: 1085 INIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLM---DDNRKYWNRVSHFTKQT 915
            +       +  IQ           +I+    E QE++  +   ++N      +     Q 
Sbjct: 559  LQKEISSKSSEIQAKNDEIENLNKEIEQIKKENQELNEELFQNNENNSNDEEIEKLKTQI 618

Query: 914  QSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKD 735
            QSLQ  + +L Q                     N+ + Q++EL     +L +H +   ++
Sbjct: 619  QSLQKEISDLSQ-------------------QNNNYKSQVEELK---EELEKHQSEQDEN 656

Query: 734  VKFGFAWANSMHDLNGQEQKLKVD-EEVPILCHQNSKIAERLD--INTDKARALDMEVQR 564
               G+   N   +L  + + LK   EE+    +Q     +  +   N ++   L  E+++
Sbjct: 657  ---GWGEENESEELKSENENLKKQIEELKEQLNQKEDQGQEENGWCNENETEDLKSEIEQ 713

Query: 563  IRLILSRIPTKPTEEASKMRVPLRAFLVGSKKDQSK 456
            ++     +      E+ K ++      +  K+DQ +
Sbjct: 714  LKKENETLKQNNETESLKKQIEELKEQLKQKEDQGQ 749


>ref|XP_001330650.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
            gi|121897262|gb|EAY02389.1| viral A-type inclusion
            protein, putative [Trichomonas vaginalis G3]
          Length = 1662

 Score =  125 bits (315), Expect = 9e-26
 Identities = 185/899 (20%), Positives = 382/899 (42%), Gaps = 28/899 (3%)
 Frame = -3

Query: 3221 HQKILEDYYALQKKAGELQTKVHIREE--ESCKHLTEALENHIYGSLLESCVVDREAHIK 3048
            ++   E+   L++K  EL+ K    E+  E  K L E ++N    S  E    D E  I+
Sbjct: 642  NESYTEESDELKQKLKELEQKYKDTEKSNEDLKKLLEQVDNLQKES--EKINQDLEKQIE 699

Query: 3047 QLMEQM----NALVKEK-RELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQ 2883
            +  E      N ++K+K  ELE++ +  E++++ LK E   LK+     +E   +  E +
Sbjct: 700  ENQENSDVDENEILKQKVTELESEVKEKEKLNEELKKENEDLKKEVENLQENAWNETENE 759

Query: 2882 ENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSA-------LQNDMQ 2724
            E    L ++NE +  ++E NN  L        +L  KL E+E ++S        L+  + 
Sbjct: 760  EIKEKLEKENEILQKQVEENNKTLN-------DLKQKLSESENEKSVKNSENDKLKQKVT 812

Query: 2723 SVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSK 2544
             +E    +S  +   L ++L +L  ++  L++ + ++ +    ++K+  DL+NQ  ++ K
Sbjct: 813  EIESDFKISNEKSSNLQQKLDVLSQNLEKLEKEMKISSEKNQKLQKENSDLQNQFTSLQK 872

Query: 2543 ELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTL 2364
            +   +   + K+ S LK  SE E    NQL   + QN      +E      +++ ++  +
Sbjct: 873  Q---NSDNQLKITSLLKEKSELE----NQLNENSTQN------LESNSSEKEIRDLKEKI 919

Query: 2363 LKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDA 2184
             K  NEKI +L         EV+   + +   D + +D   + +E+     +++K+N + 
Sbjct: 920  TKQ-NEKIKEL-------EEEVKKGYQDLWGADSD-DDSKEKDEEIKNLKLEIEKINKNH 970

Query: 2183 GAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIR 2004
              K+ GI+E             +E    I    N  + +++ L++  +  ++L    EI 
Sbjct: 971  LEKI-GIVE-------------KEKKNEIEKRENKIKKMRIDLQKKDEEINKL--NKEIS 1014

Query: 2003 AQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQN 1824
              +              +  LK++N+ ++ E     KE+   + +L+    +N    S+ 
Sbjct: 1015 QNKKDEWSTVTFGDDEEISSLKKENERIKQEITEKQKEIEEIQQKLSKFTKENEEKSSEI 1074

Query: 1823 RSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILL 1644
              LK E           +E+ +V+E E+  L   +E   S  KE+++ +          L
Sbjct: 1075 SLLKKE----------NEEKLSVLEKENEELKQRIEEFNSFKKENEENKQKIYN-----L 1119

Query: 1643 GQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAE 1464
            G+  +    +I   +   E+L + L+E+    NE  K K   + ++++ +  N      E
Sbjct: 1120 GEETKKKLNEISVLKKENEELKQKLNEI----NEEMKQK---IVDFNE-KFSNSKKENEE 1171

Query: 1463 AMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSRE 1284
             +SVL  K   N +    EF +  ++S      +NK        Q+L++  E  ETK ++
Sbjct: 1172 KLSVL-KKENDNLKQKLNEFNSFMKESE-----ENK--------QRLNDLGE--ETK-KK 1214

Query: 1283 AQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHRE 1104
               +  + EEM+Q +SD+             ++  K+ N RL   +K      +     E
Sbjct: 1215 LSILKKENEEMKQNISDL-------------MKENKELNERLSKSIKENEENKKKLNENE 1261

Query: 1103 GSFIKEINIG------DEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWN 942
             +F +EI         +E++   +            +I     E +++   ++ N +   
Sbjct: 1262 LNFKQEIEENSLLKKENEENKQKLNEINQEMKKKLNEISNLKRENEDLKRSLNGNEEIIE 1321

Query: 941  RVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLV 762
             ++   K+  S++   +E++Q                    +  ++K+ ++LN  + Q+ 
Sbjct: 1322 EMNEINKENDSIKKENKEMKQNL------------------IPKLQKENEKLNNEISQIQ 1363

Query: 761  EHNTRLKKDVKFGFAWANSMHDLNGQEQKLK--------VDEEVPILCHQNSKIAERLD 609
              N +LKK ++     +N +  L  + + LK        +++E   L  +N K+ ++++
Sbjct: 1364 IENEKLKKQIEEMKQISNEISQLKQENEDLKRSLNGNQEINKENDDLKKENEKLNQKME 1422



 Score =  102 bits (255), Expect = 8e-19
 Identities = 200/959 (20%), Positives = 410/959 (42%), Gaps = 96/959 (10%)
 Frame = -3

Query: 3050 KQLMEQMNALVKEKRELENDAQRGEEISQSLKD-EVFQLK-EVSRLYEEEKQHT-IELQE 2880
            K++ EQ   +     EL ND     + ++S KD E+  LK ++ +L + + Q +      
Sbjct: 96   KKIAEQQQEIESLNNELWND-----DPNESEKDIEIQNLKSQIQKLTKNQPQVSPASNNA 150

Query: 2879 NFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAV 2700
              + LR +  ++  K +  +NL    + II EL     EN++    L ND   +E+  A 
Sbjct: 151  ELDTLRSQLAEMTQKTKEFSNL----EIIIKELR---AENDQLNDELMNDQAELEEKDAE 203

Query: 2699 SQTERE-----------------ELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDL 2571
             Q  +E                 EL ++ +    +++   +AL   + ++   +KQLQ+ 
Sbjct: 204  IQELKEQNEGAYKMKYETATKTIELLQKQISASQEISKENDALKSKLAEK---DKQLQNY 260

Query: 2570 ENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSL 2391
             N   ++ KE    + +  K   D    +E E+  +N++    +Q ++L+ E +  +G +
Sbjct: 261  -NDMNSLIKEQREQIEKLSKNIDDSSDFAENEKKYQNEIQNLKKQIEELQ-ENDNAWGDI 318

Query: 2390 ----QMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVG 2223
                ++KQ EN  LK   E + +  K +     +++ + + I+K+  +  + L +  E  
Sbjct: 319  DDTDEIKQ-ENENLKKEIENLKNQNKEIGNLQLQIE-KLKDIIKEKESDNESLLQELEKS 376

Query: 2222 RSATDMKKV---NSDAGAKVSGILEMLLPMK---------DDVFSLKEEVLGNINSLRND 2079
             +  +++K+   N +   KV  + E +  ++         D++    +++   IN+L+ +
Sbjct: 377  ENNFEIEKIKKENQNLQTKVKEMQETIDELESNAWNDDGNDEIKQNLDKLKQEINNLKKE 436

Query: 2078 AQMVQVALEQMQDTKSELFAEAEIR--AQEVLRLQAEVDAIQHI---------LIELKRK 1932
             + +Q  +E+ ++         EI    Q + +LQ E + ++ I         + +LK++
Sbjct: 437  NENLQKQVEENEENAWNDGNNDEIEEIKQNLEKLQKENENLKKINEEKSNDDEINKLKQE 496

Query: 1931 NQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVV 1752
               L+ E++   + LWN     +N   +  NL+ +N  LK  +  + QK  +  EE    
Sbjct: 497  ISELKKENEELQENLWNENENEDN-QEEISNLKKENEKLKQNIK-ELQKQIETNEENLWN 554

Query: 1751 ESEHNV------LSSEVEN---LKSE----LKESKDLEGYFLRLFEILL-----GQHVEV 1626
            E+E+++      L SEV+N   LK E     KE+++L+     L E +       Q  E 
Sbjct: 555  ENENDLKQKVTELESEVKNSDKLKEENNKLKKENEELKKEIDDLTENVWKDDEDNQETEK 614

Query: 1625 ASLDIESCRFAEEKLMRILDEL------ICLRNENAKLK---NEALYEYHDYERKNVSGS 1473
               +I + +   E+L + +DEL           E+ +LK    E   +Y D E+ N    
Sbjct: 615  LKQEINNLKKENEELKKEMDELQESTWNESYTEESDELKQKLKELEQKYKDTEKSNEDLK 674

Query: 1472 R-AEAMSVLISKSLGNGRANQREFQNKEEDS--SGVDLLKNKCTRLEFQVQKLSEKAEMF 1302
            +  E +  L  +S    +  +++ +  +E+S     ++LK K T LE +V+   EK ++ 
Sbjct: 675  KLLEQVDNLQKESEKINQDLEKQIEENQENSDVDENEILKQKVTELESEVK---EKEKLN 731

Query: 1301 ETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKK---ENTRLRSEMKGELT 1131
            E   +E + +  ++E +Q+   +                 L+K   EN +  +++K +L+
Sbjct: 732  EELKKENEDLKKEVENLQENAWNETENEEIKEKLEKENEILQKQVEENNKTLNDLKQKLS 791

Query: 1130 PS---RSFKHREGSFIK--------EINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQ 984
             S   +S K+ E   +K        +  I +E  + L Q                   ++
Sbjct: 792  ESENEKSVKNSENDKLKQKVTEIESDFKISNEKSSNLQQKLDVLSQNLEKLEKEMKISSE 851

Query: 983  EIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIE 804
            +   L  +N    N+ +   KQ    Q  +  L +              +   ++ NS E
Sbjct: 852  KNQKLQKENSDLQNQFTSLQKQNSDNQLKITSLLKEKSELENQLNENSTQ--NLESNSSE 909

Query: 803  KQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEEVPILCHQNSKI 624
            K++++L   + +  E    L+++VK G+     +   +  +   + DEE+  L  +  KI
Sbjct: 910  KEIRDLKEKITKQNEKIKELEEEVKKGY---QDLWGADSDDDSKEKDEEIKNLKLEIEKI 966

Query: 623  ----AERLDINTDKARALDMEVQRIRLILSRIP-TKPTEEASKMRVPLRAFLVGSKKDQ 462
                 E++ I  +K +  ++E +  ++   RI   K  EE +K+   +      +KKD+
Sbjct: 967  NKNHLEKIGI-VEKEKKNEIEKRENKIKKMRIDLQKKDEEINKLNKEISQ----NKKDE 1020



 Score = 66.6 bits (161), Expect = 7e-08
 Identities = 140/750 (18%), Positives = 288/750 (38%), Gaps = 46/750 (6%)
 Frame = -3

Query: 2678 LNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASD 2499
            L ++   +RD    L +  + +VD+ + +E+  Q LE+ K  +S  L  SVS++    S 
Sbjct: 16   LKQKTARIRDLEKMLSQMNAPSVDNSSKIEELEQQLEDSKALISA-LQESVSQKNAEISR 74

Query: 2498 LKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLL 2319
            L  +S+     +N  LI + Q K  E + E       ++ + N L  D   +        
Sbjct: 75   LSLISQSNARNQNSDLIASLQKKIAEQQQE-------IESLNNELWNDDPNE-------- 119

Query: 2318 ATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLP-M 2142
            + K  E+Q  +  I K   N       +          +        K    LE+++  +
Sbjct: 120  SEKDIEIQNLKSQIQKLTKNQPQVSPASNNAELDTLRSQLAEMTQKTKEFSNLEIIIKEL 179

Query: 2141 KDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAI 1962
            + +   L +E++ +   L      +Q   EQ +      +   E   + +  LQ ++ A 
Sbjct: 180  RAENDQLNDELMNDQAELEEKDAEIQELKEQNEGAYKMKY---ETATKTIELLQKQISAS 236

Query: 1961 QHILIE-------LKRKNQTLQDESQRNA--KELWNAKARLNNVMSKNINLESQNRSLKA 1809
            Q I  E       L  K++ LQ+ +  N+  KE      +L+  +  + +     +  + 
Sbjct: 237  QEISKENDALKSKLAEKDKQLQNYNDMNSLIKEQREQIEKLSKNIDDSSDFAENEKKYQN 296

Query: 1808 ELHLQAQKAFQIQEERNV---------VESEHNVLSSEVENLKSELKESKDLEGYFLRLF 1656
            E+    ++  ++QE  N          ++ E+  L  E+ENLK++ KE  +L+    +L 
Sbjct: 297  EIQNLKKQIEELQENDNAWGDIDDTDEIKQENENLKKEIENLKNQNKEIGNLQLQIEKLK 356

Query: 1655 EILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNV-- 1482
            +I+  +  +  SL  E     E+       E I   N+N + K + + E  D    N   
Sbjct: 357  DIIKEKESDNESLLQE----LEKSENNFEIEKIKKENQNLQTKVKEMQETIDELESNAWN 412

Query: 1481 --SGSRAEAMSVLISKSLGNGRANQREFQ---NKEEDSSGVDLLKNKCTRLEFQVQKLSE 1317
                   +     + + + N +      Q    + E+++  D   ++   ++  ++KL +
Sbjct: 413  DDGNDEIKQNLDKLKQEINNLKKENENLQKQVEENEENAWNDGNNDEIEEIKQNLEKLQK 472

Query: 1316 KAE----MFETKSRE-----AQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENT 1164
            + E    + E KS +      +Q  ++L++  + L +              + +LKKEN 
Sbjct: 473  ENENLKKINEEKSNDDEINKLKQEISELKKENEELQENLWNENENEDNQEEISNLKKENE 532

Query: 1163 RLRSEMKG-----ELTPSRSFKHREGSF---IKEINIGDEDDTPLIQ---XXXXXXXXXX 1017
            +L+  +K      E      +   E      + E+    ++   L +             
Sbjct: 533  KLKQNIKELQKQIETNEENLWNENENDLKQKVTELESEVKNSDKLKEENNKLKKENEELK 592

Query: 1016 XKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXX 837
             +ID  T    + D    +  K    +++  K+ + L+  + ELQ+              
Sbjct: 593  KEIDDLTENVWKDDEDNQETEKLKQEINNLKKENEELKKEMDELQESTWNESYTE----- 647

Query: 836  KWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEE 657
                 + + ++++LKEL        + N  LKK ++        + +L  + +K+  D E
Sbjct: 648  -----ESDELKQKLKELEQKYKDTEKSNEDLKKLLE-------QVDNLQKESEKINQDLE 695

Query: 656  VPILCHQNSKIAERLDINTDKARALDMEVQ 567
              I  +Q +   +  +I   K   L+ EV+
Sbjct: 696  KQIEENQENSDVDENEILKQKVTELESEVK 725


>ref|XP_001312904.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
            gi|121894768|gb|EAX99974.1| viral A-type inclusion
            protein, putative [Trichomonas vaginalis G3]
          Length = 3748

 Score =  125 bits (315), Expect = 9e-26
 Identities = 192/978 (19%), Positives = 414/978 (42%), Gaps = 83/978 (8%)
 Frame = -3

Query: 3191 LQKKAGELQTKVHIREE--ESCKHLTEALENHIYGSLLES----CVVDREAH-IKQLMEQ 3033
            LQ++  E++ K+  +++  E C  L  AL+   Y  L        V++ +A  I+Q +++
Sbjct: 1663 LQQQIEEIKDKITDKQKKNEECSQLNTALKEE-YDQLKSEFDNIAVIESKAEEIQQKIDE 1721

Query: 3032 MNALVKEKRELENDAQRG----EEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNAL 2865
            + + + +KR+   D + G    EE     + E+ Q++ V    E+ +    E+ E  N+ 
Sbjct: 1722 IKSEIDQKRKEYQDIKEGNDLLEEAYTEKQKELEQIEVVEDKTEDLQNLIDEITEQINSR 1781

Query: 2864 RQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTER 2685
            +  N    L+ + +N   E++   + +L  +L           ND+   +      + E 
Sbjct: 1782 KSNN----LERQVSNETFEKQ---LGQLKQEL-----------NDLPQTDDNSESLKEEI 1823

Query: 2684 EELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLA 2505
            EE  ++L +++D+   + +      D+   +E +L DLENQK  +  E  +   ++ +  
Sbjct: 1824 EETKKKLAMMKDEYQRMSDEDKSLTDELIRVESELNDLENQKNVLENETIVKAEKKMQND 1883

Query: 2504 SDLKALSEKEESTKNQLLIQ---TEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYD 2334
            + +  L  K ++ K QL  Q    E  ++L+ E ++L      K  +N      +E    
Sbjct: 1884 NTIMDLRNKIDTLKAQLQQQEKPQEDIEKLKKEYQELKFQFDAKVSQNKEEVSHSENELH 1943

Query: 2333 LCKLLATKSREVQGQQEGILKQDI-----NIEDELARTKEVGRSATDM------------ 2205
              K +  K  +V+ QQ   LK  I      I+D+  + +E+ +    +            
Sbjct: 1944 SLKEMYDKIEKVEQQQVDSLKSQILSVKAQIDDQNKKNEEMKKQIEKLTSEKSDAQNELE 2003

Query: 2204 ---KKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGN-----------INSLRNDAQM- 2070
                KV+ D   ++S  +E L    D+     EEV  +           + +L++D Q  
Sbjct: 2004 KAENKVDPDELVRLSEEIEELKLEADEKKKQNEEVRSSLEEELSKYKEILENLKSDNQSD 2063

Query: 2069 VQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQ----DESQR 1902
            +   ++Q++D  +E   E E   Q   +LQ  ++  + +L  + ++++ +Q     E  +
Sbjct: 2064 IHNQIDQIKDRINEKQQENEADNQ---KLQEIINNHKKLLENMNKEHEEIQKQIEQEVDK 2120

Query: 1901 NAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQK-AFQIQEERNVVESEHNVLSS 1725
            N KE+   +  +N V  K    + +N   K EL  Q      +I++ +N  +SE ++L  
Sbjct: 2121 NNKEIDQKQKEINEVKEKLQQAKKENEDDKVELQRQIDNCGREIEKLQNAGDSEIDLLKQ 2180

Query: 1724 EVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRN 1545
            E++  + E +++ + + + + +++  L QH E      E+   AE+           L N
Sbjct: 2181 EIDKKEKERQQATEQKQHEIEMYKAKL-QHKEQ-----ENAVNAEK-----------LHN 2223

Query: 1544 ENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLL 1365
            E   LK +   +  +Y+  N      E+++ ++ K        + E +N++E +  V+ L
Sbjct: 2224 EIENLKKKIDSQEMEYKNYN------ESLTKILDKLKVKLEEVEEENRNEDERAEEVENL 2277

Query: 1364 K----NKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXX 1197
            K    +K  + + + +KLS++    + + +  Q+   ++EEM+QT+ D+           
Sbjct: 2278 KAQIASKRKQNDAENEKLSQEINKLKEELQNLQE-NTEIEEMKQTVEDLKTQISVFGDPE 2336

Query: 1196 IRVRSLKKENTRL-------------RSEMKGELTPSRSFKHREGSFIKEINIGDEDDTP 1056
                 L+KE   L               +++ ++   ++ K R+   ++ I++G+E+D  
Sbjct: 2337 QEKIKLQKEIDELTEKTEKLAEADDENDKLREQIENLKNVKSRD---VEIIDLGEEEDGE 2393

Query: 1055 LIQXXXXXXXXXXXKIDTRTSE------------TQEIDTLMDDNRKYWNRVSHFTKQTQ 912
              Q               + ++            +++ID +   N+    + S   K+  
Sbjct: 2394 RQQLVEELNKLKEEYEQLQNTDDINDLKQEVIDLSKQIDEIKASNKDAQTK-SDLLKELS 2452

Query: 911  SLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNT---RLK 741
             L + ++ + Q                  +D    E+  KEL+    QL +  +   +LK
Sbjct: 2453 QLNSQIENIIQEEEDKEEIRSHIEEIKSLLDNKQSEEDEKELDDLKKQLEDKQSLINKLK 2512

Query: 740  KDVKFGFAWANSMHDLNGQEQKLKVDEEVPILCHQNSKIAERLDINTDKARALDMEVQRI 561
            +D+K          + N + QK  +D+        N++  E    + ++ + L+ E++R+
Sbjct: 2513 EDIKL-------TKEENEKAQK-NIDDLEQEFDDLNNEYEEESQFDEER-KLLETEIERL 2563

Query: 560  RLILSRIPTKPTEEASKM 507
            + ++S   T+  E+  K+
Sbjct: 2564 KQLISEKKTQNKEKTDKL 2581



 Score =  120 bits (300), Expect = 5e-24
 Identities = 181/953 (18%), Positives = 395/953 (41%), Gaps = 53/953 (5%)
 Frame = -3

Query: 3224 QHQKILEDYYALQKKAGELQTKVHIREEESCKHLTEALEN-----------HIYGSLLES 3078
            Q  K+ + Y  L+K+  E   ++  +  +    L E L+N           H     +  
Sbjct: 702  QRSKVEQKYKDLEKQNKEKSDEIE-KVSKEISELKEKLDNLNQFKDNTPELHQKVDAMNE 760

Query: 3077 CVVDREAHIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQH 2898
             +V +    +++ E+MN L +E + LEN+ +  E ++   +    ++  + +  EE+K+ 
Sbjct: 761  QIVKKSQENEKIQEEMNKLNEELQHLENEMEEIEVVNDERETIQEKIDNIKQQIEEKKKS 820

Query: 2897 TIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSV 2718
              E+Q+  N L          IEA N+  ++ D+I                         
Sbjct: 821  NEEIQDIMNLL----------IEAENDAQKELDDI------------------------- 845

Query: 2717 EQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKEL 2538
                 + + + EE+ +++  L+D++   K+  +   +    ++K+L+DL+N+ +      
Sbjct: 846  ----EIVEAQSEEIRQRIQTLQDNLQDRKKLNNELTEQNNKLQKELKDLQNELDQTELVN 901

Query: 2537 ALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLK 2358
              S S  +KL    + ++E++   +N     TEQN++L  EIEK    L     E  +++
Sbjct: 902  DDSESLNKKLDEIKEQINERKSQNEN----NTEQNEKLIEEIEKFAKELD----EIEIIE 953

Query: 2357 DGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGA 2178
            D ++K+      L  +  E Q   E   K + ++E EL  TK+   S + +K  NSD   
Sbjct: 954  DKSDKLQAQISELQKQIDEKQKNNEQTDKSNNDLEHELQITKQKLDSMSSVKN-NSDY-- 1010

Query: 2177 KVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQ 1998
                       +K ++ ++ +E    I  +R+    ++   +++QD   EL    +I A 
Sbjct: 1011 -----------LKSEIENVNKE----IEKIRDTNNKLK---QELQDKNKELEEMTDI-AD 1051

Query: 1997 EVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRS 1818
                L+ ++D++   + +    N T+ +  +   ++L NA+A+L ++   + N +S  +S
Sbjct: 1052 NSEELKEKIDSVNEEITKRVANNTTIDELIRHLHEDLKNAEAKLQSIPHVDDNTDSLQKS 1111

Query: 1817 L-------------KAELHLQAQKAFQIQEER-------NVVESEHNVLSSEVENLKSEL 1698
            L               EL+ +  +  Q +EE+         +  +   +SSE+E +KS++
Sbjct: 1112 LDEVLAQISQKQRENDELNDEISRLIQEKEEKTDELNNMETIPDKREEISSEIETVKSQI 1171

Query: 1697 KESK---------------DLEGYFLRLFEI-LLGQHVEVASLDIESCRFAEEKLMRILD 1566
            +E K               +LE     L ++    Q +E    +IE+ +    +  + LD
Sbjct: 1172 EEKKKNNEKIAEENKKLAEELENLRQTLSKMETSDQPLENIQKEIETTKQEISEKQKELD 1231

Query: 1565 ELICLRNENAKLKNEALYEYHDY--ERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKE 1392
            E   L+ E  ++K+E   +  +   E +N+  ++ +  +    +   N    Q E   K 
Sbjct: 1232 E---LKQELEQIKDEDQSKADEISEEIENIK-TQIDEKNKKNEEIAKNNEEKQSELDEKL 1287

Query: 1391 EDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXX 1212
            ++   ++ +K++   +  Q+++  ++ E  + +     ++  +L++++Q L  +      
Sbjct: 1288 KELQDLEEIKDETEEINQQIEETQKEIETKKQQKENNNKLNEELDKLKQDLEQI------ 1341

Query: 1211 XXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXX 1032
                   V  L +E  +++S++          KH+  + IKE N   E++   ++     
Sbjct: 1342 -ENVEDNVEKLTEEIEKVKSDIDS--------KHQLNNDIKEANEVVEEELNSLKEELEK 1392

Query: 1031 XXXXXXKIDTRTSE----TQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXX 864
                  K D    E     +EI+T    N           K+   L+N ++E+ +     
Sbjct: 1393 IEPVEDKSDEIRKEIVKIQKEIETKKATNCGISESNELLNKELNDLKNQLEEIAEEKD-- 1450

Query: 863  XXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQ 684
                          D   I+ +++ L+  + +  EHN   ++            ++ N +
Sbjct: 1451 --------------DSEEIKAEIENLHKSIEEKKEHNANTQQ------------NNENMK 1484

Query: 683  EQKLKVDEEVPILCHQNSKIAERLDINTDKARALDMEVQRIRLILSRIPTKPT 525
            E+  K+ EE            +++++  DKA  +  E+++++   S+I  K T
Sbjct: 1485 EELSKLQEEF-----------DQIEVVEDKAEEIHSEIEKLK---SQIEEKNT 1523



 Score =  114 bits (284), Expect = 4e-22
 Identities = 153/801 (19%), Positives = 350/801 (43%), Gaps = 66/801 (8%)
 Frame = -3

Query: 3086 LESCVVDREAHIKQLMEQMNALVKEKRELENDAQRGEEI---SQSLKDEVFQLKEVSRLY 2916
            L+  + DR+    +L EQ N L KE ++L+N+  + E +   S+SL  ++ ++KE  ++ 
Sbjct: 862  LQDNLQDRKKLNNELTEQNNKLQKELKDLQNELDQTELVNDDSESLNKKLDEIKE--QIN 919

Query: 2915 EEEKQHTIELQENFNALRQ-----KNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQ 2751
            E + Q+    ++N   + +     K  D    IE  ++ L+ + + + +   + Q+N EQ
Sbjct: 920  ERKSQNENNTEQNEKLIEEIEKFAKELDEIEIIEDKSDKLQAQISELQKQIDEKQKNNEQ 979

Query: 2750 RSALQNDM--------QSVEQMHAVS------QTEREELNRQLVLLRDDVNHLKEAL--- 2622
                 ND+        Q ++ M +V       ++E E +N+++  +RD  N LK+ L   
Sbjct: 980  TDKSNNDLEHELQITKQKLDSMSSVKNNSDYLKSEIENVNKEIEKIRDTNNKLKQELQDK 1039

Query: 2621 SMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSE--KEESTKNQLLI 2448
            +  +++   +    ++L+ + ++V++E+   V+    +   ++ L E  K    K Q + 
Sbjct: 1040 NKELEEMTDIADNSEELKEKIDSVNEEITKRVANNTTIDELIRHLHEDLKNAEAKLQSIP 1099

Query: 2447 QTEQN-KQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILK 2271
              + N   L+  ++++   +  KQ EN  L D      ++ +L+  + +E +  +   ++
Sbjct: 1100 HVDDNTDSLQKSLDEVLAQISQKQRENDELND------EISRLI--QEKEEKTDELNNME 1151

Query: 2270 QDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINS 2091
               +  +E++   E  +S  + KK N++  A+ +                 +++   + +
Sbjct: 1152 TIPDKREEISSEIETVKSQIEEKKKNNEKIAEEN-----------------KKLAEELEN 1194

Query: 2090 LRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDE 1911
            LR     ++ + + +++ + E+    E   QE+   Q E+D ++  L ++K ++Q+  DE
Sbjct: 1195 LRQTLSKMETSDQPLENIQKEI----ETTKQEISEKQKELDELKQELEQIKDEDQSKADE 1250

Query: 1910 SQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKA--------------FQI 1773
                ++E+ N K +++    KN  +   N   ++EL  + ++                QI
Sbjct: 1251 I---SEEIENIKTQIDEKNKKNEEIAKNNEEKQSELDEKLKELQDLEEIKDETEEINQQI 1307

Query: 1772 QEERNVVESE------HNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDI 1611
            +E +  +E++      +N L+ E++ LK +L++ +++E    +L E      +E    DI
Sbjct: 1308 EETQKEIETKKQQKENNNKLNEELDKLKQDLEQIENVEDNVEKLTE-----EIEKVKSDI 1362

Query: 1610 -----------ESCRFAEEKLMRILDELICL---RNENAKLKNEALYEYHDYERKNVSGS 1473
                       E+    EE+L  + +EL  +    +++ +++ E +    + E K  +  
Sbjct: 1363 DSKHQLNNDIKEANEVVEEELNSLKEELEKIEPVEDKSDEIRKEIVKIQKEIETKKATNC 1422

Query: 1472 RAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETK 1293
                 + L++K L N   NQ E   +E+D S           ++ +++ L +  E  E K
Sbjct: 1423 GISESNELLNKEL-NDLKNQLEEIAEEKDDS---------EEIKAEIENLHKSIE--EKK 1470

Query: 1292 SREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFK 1113
               A    N  E M++ LS +            +   +  E  +L+S+++ + T +   K
Sbjct: 1471 EHNANTQQNN-ENMKEELSKLQEEFDQIEVVEDKAEEIHSEIEKLKSQIEEKNTTNNDIK 1529

Query: 1112 HREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRV- 936
                   +E+N         +Q           K +  + +  ++  L+++ +     + 
Sbjct: 1530 EANDILNEELN--------NLQKQYDEIDVEEDKSEELSQKVTDLQKLLEEKKSQNETIK 1581

Query: 935  ---SHFTKQTQSLQNSVQELQ 882
                +  K+ QSLQN +  ++
Sbjct: 1582 SGNENILKELQSLQNELDNIE 1602



 Score =  110 bits (274), Expect = 5e-21
 Identities = 131/713 (18%), Positives = 316/713 (44%), Gaps = 49/713 (6%)
 Frame = -3

Query: 3224 QHQKILEDYYALQKKAGELQT------KVHIREEESCKHLTEALENHIYGSLLESCVVDR 3063
            Q++K++E+     K+  E++       K+  +  E  K + E  +N+       + +   
Sbjct: 931  QNEKLIEEIEKFAKELDEIEIIEDKSDKLQAQISELQKQIDEKQKNNEQTDKSNNDLEHE 990

Query: 3062 EAHIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQ 2883
                KQ ++ M+++      L+++ +   +  + ++D   +LK+  +   +E +   ++ 
Sbjct: 991  LQITKQKLDSMSSVKNNSDYLKSEIENVNKEIEKIRDTNNKLKQELQDKNKELEEMTDIA 1050

Query: 2882 ENFNALRQK----NEDICLKIEANNNLLEQKDNIIVELSH---KLQEN---EEQRSALQN 2733
            +N   L++K    NE+I  ++  N  + E   ++  +L +   KLQ     ++   +LQ 
Sbjct: 1051 DNSEELKEKIDSVNEEITKRVANNTTIDELIRHLHEDLKNAEAKLQSIPHVDDNTDSLQK 1110

Query: 2732 DMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKET 2553
             +  V    +  Q E +ELN ++  L  +    KE  +  +++   +  + +++ ++ ET
Sbjct: 1111 SLDEVLAQISQKQRENDELNDEISRLIQE----KEEKTDELNNMETIPDKREEISSEIET 1166

Query: 2552 VSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLE---LEIEKLYGSLQMK 2382
            V  ++       +K+A + K L+E+ E+ +  L      ++ LE    EIE     +  K
Sbjct: 1167 VKSQIEEKKKNNEKIAEENKKLAEELENLRQTLSKMETSDQPLENIQKEIETTKQEISEK 1226

Query: 2381 QMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMK 2202
            Q E   LK   E+I D  +   +K+ E+  + E I  Q   I+++  + +E+ ++  + K
Sbjct: 1227 QKELDELKQELEQIKDEDQ---SKADEISEEIENIKTQ---IDEKNKKNEEIAKN-NEEK 1279

Query: 2201 KVNSDAGAKVSGILEMLLPMKDDV----------FSLKEEVLGNINSLRNDAQMVQVALE 2052
            +   D   K    LE +    +++             K++   N N L  +   ++  LE
Sbjct: 1280 QSELDEKLKELQDLEEIKDETEEINQQIEETQKEIETKKQQKENNNKLNEELDKLKQDLE 1339

Query: 2051 QMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKA 1872
            Q+++ +  +    E   +E+ ++++++D+   +  ++K  N+ +++E     +EL     
Sbjct: 1340 QIENVEDNV----EKLTEEIEKVKSDIDSKHQLNNDIKEANEVVEEELNSLKEEL----E 1391

Query: 1871 RLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKE 1692
            ++  V  K+  +  +   ++ E+  +      I E   ++  E N L +++E +  E  +
Sbjct: 1392 KIEPVEDKSDEIRKEIVKIQKEIETKKATNCGISESNELLNKELNDLKNQLEEIAEEKDD 1451

Query: 1691 SKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEE--KLMRILDELICLRNENAKLKNEA 1518
            S++++     L + +  +    A+    +    EE  KL    D++  + ++  ++ +E 
Sbjct: 1452 SEEIKAEIENLHKSIEEKKEHNANTQQNNENMKEELSKLQEEFDQIEVVEDKAEEIHSEI 1511

Query: 1517 LYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVD--------LLK 1362
                   E KN + +  +  + ++++ L N +    E   +E+ S  +         LL+
Sbjct: 1512 EKLKSQIEEKNTTNNDIKEANDILNEELNNLQKQYDEIDVEEDKSEELSQKVTDLQKLLE 1571

Query: 1361 NKCTRLEF----------QVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSD 1233
             K ++ E           ++Q L  + +  E  S  +++   K+E+++Q +SD
Sbjct: 1572 EKKSQNETIKSGNENILKELQSLQNELDNIEVVSSSSEEGEKKIEKLKQMISD 1624



 Score =  110 bits (274), Expect = 5e-21
 Identities = 181/910 (19%), Positives = 391/910 (42%), Gaps = 59/910 (6%)
 Frame = -3

Query: 3149 REEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNALVKEKRELENDAQRGEEI 2970
            ++ E  K   E L +    +  E    + +    +L+     + + K E +   ++ EE+
Sbjct: 1979 KKNEEMKKQIEKLTSEKSDAQNELEKAENKVDPDELVRLSEEIEELKLEADEKKKQNEEV 2038

Query: 2969 SQSLKDEVFQLKEVSRLYEEEKQHTI-----ELQENFNALRQKNEDICLKIEA--NN--- 2820
              SL++E+ + KE+    + + Q  I     ++++  N  +Q+NE    K++   NN   
Sbjct: 2039 RSSLEEELSKYKEILENLKSDNQSDIHNQIDQIKDRINEKQQENEADNQKLQEIINNHKK 2098

Query: 2819 ---NLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTERE----ELNRQLV 2661
               N+ ++ + I  ++  ++ +N ++    Q ++  V++    ++ E E    EL RQ+ 
Sbjct: 2099 LLENMNKEHEEIQKQIEQEVDKNNKEIDQKQKEINEVKEKLQQAKKENEDDKVELQRQID 2158

Query: 2660 LLRDDVNHLKEALSMAVD------DRAFMEKQLQDLENQKETVSKELALSVSREQKLASD 2499
                ++  L+ A    +D      D+   E+Q Q  E ++  +    A    +EQ+ A +
Sbjct: 2159 NCGREIEKLQNAGDSEIDLLKQEIDKKEKERQ-QATEQKQHEIEMYKAKLQHKEQENAVN 2217

Query: 2498 LKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMK----QMENTLLKDGNEKIYDL 2331
             + L  + E+ K ++  Q  + K     + K+   L++K    + EN    +  E++ +L
Sbjct: 2218 AEKLHNEIENLKKKIDSQEMEYKNYNESLTKILDKLKVKLEEVEEENRNEDERAEEVENL 2277

Query: 2330 CKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILE-- 2157
               +A+K ++   + E + ++   +++EL   +E      +MK+   D   ++S   +  
Sbjct: 2278 KAQIASKRKQNDAENEKLSQEINKLKEELQNLQE-NTEIEEMKQTVEDLKTQISVFGDPE 2336

Query: 2156 ---MLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLR 1986
               + L  + D  + K E L   +   ND    Q+  E +++ KS        R  E++ 
Sbjct: 2337 QEKIKLQKEIDELTEKTEKLAEADD-ENDKLREQI--ENLKNVKS--------RDVEIID 2385

Query: 1985 LQAEVDAIQHILIE----LKRKNQTLQDESQRN--AKELWNAKARLNNVMSKNINLESQN 1824
            L  E D  +  L+E    LK + + LQ+    N   +E+ +   +++ + + N + ++++
Sbjct: 2386 LGEEEDGERQQLVEELNKLKEEYEQLQNTDDINDLKQEVIDLSKQIDEIKASNKDAQTKS 2445

Query: 1823 RSLK--AELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEI 1650
              LK  ++L+ Q +   Q +E++  + S    + S ++N +SE ++ K+L+    +L + 
Sbjct: 2446 DLLKELSQLNSQIENIIQEEEDKEEIRSHIEEIKSLLDNKQSE-EDEKELDDLKKQLED- 2503

Query: 1649 LLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSR 1470
                 +     DI+  +   EK  + +D+L     E   L NE   E    E + +  + 
Sbjct: 2504 -KQSLINKLKEDIKLTKEENEKAQKNIDDL---EQEFDDLNNEYEEESQFDEERKLLETE 2559

Query: 1469 AEAMSVLIS-KSLGNGRANQREFQ---------NKEEDSSGVDLLKNKCTRLEFQVQKLS 1320
             E +  LIS K   N     + F+         N  ED S    L+++   L  Q+  + 
Sbjct: 2560 IERLKQLISEKKTQNKEKTDKLFKEINDLTEELNSLEDDSENKELQSQIDELNEQINSVK 2619

Query: 1319 EKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKG 1140
            E++   +TK    + +  +L+++   L  M             + +LK+E    +S+ + 
Sbjct: 2620 EESNPQQTK----ENLQKELDDLNNKLQQMIEDEEENEKLKEEIDALKEELKDNKSQEEN 2675

Query: 1139 ELTPSRSFKHREGSFIKEINIGDEDD---TPLIQXXXXXXXXXXXKIDTRTSETQEIDTL 969
            +   S+  + +E    K+  I + ++   + + Q           + D   S  +EID+L
Sbjct: 2676 QQLKSQISELQEQIKQKQNEISETENSLKSQISQLQNELKEKESERGDKSNSLYKEIDSL 2735

Query: 968  MD--DNRKYWNRV--SHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEK 801
             +  +N++  N+   S  +   + L+  +QEL +              K    +M  +E+
Sbjct: 2736 KEKINNQEIENKADSSQLSDLLKDLKKKLQELTEENETIKSKISEEKEK-SKSEMAKLEE 2794

Query: 800  QLKELNIHVMQL--VEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEEVPILCHQNSK 627
            + K LN  +  +   E    L+ +V       N    +N +EQK K+ +E   L  + S+
Sbjct: 2795 EKKSLNKELENVNDDEDKEMLEGEVSSLKETLNLKKQIN-EEQKQKLSQEKEKLTEELSQ 2853

Query: 626  IAERLDINTD 597
            + +  D+  +
Sbjct: 2854 LNDNEDLKKE 2863



 Score =  109 bits (273), Expect = 7e-21
 Identities = 128/638 (20%), Positives = 292/638 (45%), Gaps = 39/638 (6%)
 Frame = -3

Query: 3050 KQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFN 2871
            K+L E++  L +   ++E   Q  E I + ++    ++ E  +  +E KQ   EL++  +
Sbjct: 1186 KKLAEELENLRQTLSKMETSDQPLENIQKEIETTKQEISEKQKELDELKQ---ELEQIKD 1242

Query: 2870 ALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQT 2691
              + K ++I  +IE     +++K+    E++   + NEE++S L   ++ ++ +  +   
Sbjct: 1243 EDQSKADEISEEIENIKTQIDEKNKKNEEIA---KNNEEKQSELDEKLKELQDLEEIKD- 1298

Query: 2690 EREELNRQLVLLRDDVN---HLKEALSMAVDDRAFMEKQLQDLENQKETVSK------EL 2538
            E EE+N+Q+   + ++      KE  +   ++   +++ L+ +EN ++ V K      ++
Sbjct: 1299 ETEEINQQIEETQKEIETKKQQKENNNKLNEELDKLKQDLEQIENVEDNVEKLTEEIEKV 1358

Query: 2537 ALSVSREQKLASDLKALSEKEESTKNQLLIQTEQ-------NKQLELEIEKLYGSLQMKQ 2379
               +  + +L +D+K  +E  E   N L  + E+       + ++  EI K+   ++ K+
Sbjct: 1359 KSDIDSKHQLNNDIKEANEVVEEELNSLKEELEKIEPVEDKSDEIRKEIVKIQKEIETKK 1418

Query: 2378 MENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKK 2199
              N  + + NE       LL  +  +++ Q E I ++  + E+  A  + + +S  + K+
Sbjct: 1419 ATNCGISESNE-------LLNKELNDLKNQLEEIAEEKDDSEEIKAEIENLHKSIEEKKE 1471

Query: 2198 VNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFA 2019
             N++       + E L  ++++ F   E V      + ++ + ++  +E+   T +++  
Sbjct: 1472 HNANTQQNNENMKEELSKLQEE-FDQIEVVEDKAEEIHSEIEKLKSQIEEKNTTNNDIKE 1530

Query: 2018 EAEIRAQEVLRLQAEVDAI-----------------QHILIELKRKNQTLQDESQRNAKE 1890
              +I  +E+  LQ + D I                 Q +L E K +N+T++  ++   KE
Sbjct: 1531 ANDILNEELNNLQKQYDEIDVEEDKSEELSQKVTDLQKLLEEKKSQNETIKSGNENILKE 1590

Query: 1889 LWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHN-VLSSEVEN 1713
            L + +  L+N+   + + E   + ++     + ++    ++++N   ++HN  L +++++
Sbjct: 1591 LQSLQNELDNIEVVSSSSEEGEKKIE-----KLKQMISDKQKQNEETTKHNEELDNQIKD 1645

Query: 1712 LKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAK 1533
            L++EL E                   + V     +  +  EE   +I D+    +NE   
Sbjct: 1646 LENELNEI------------------IPVKDKSNDLQQQIEEIKDKITDKQ--KKNEECS 1685

Query: 1532 LKNEALYEYHD-----YERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDL 1368
              N AL E +D     ++   V  S+AE +   I +        ++E+Q+ +E   G DL
Sbjct: 1686 QLNTALKEEYDQLKSEFDNIAVIESKAEEIQQKIDEIKSEIDQKRKEYQDIKE---GNDL 1742

Query: 1367 LKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEE 1254
            L+   T    + QK  E+ E+ E K+ + Q + +++ E
Sbjct: 1743 LEEAYT----EKQKELEQIEVVEDKTEDLQNLIDEITE 1776



 Score =  105 bits (262), Expect = 1e-19
 Identities = 175/908 (19%), Positives = 384/908 (42%), Gaps = 70/908 (7%)
 Frame = -3

Query: 3092 SLLESCVVDREAHIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKE-VSRLY 2916
            +LL   +    A  K  M+ +   +++K E   + +   ++S S   E+  + E  S+L 
Sbjct: 170  ALLIKQLYRENARSKVQMDSLRKQLQDKDEEIKNLKAATDLSNSRISELSGIIEGESKLS 229

Query: 2915 EEEKQHTIELQENF----NALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQEN---- 2760
            E +   +     NF    N   ++ + +  +++     +E ++     L++ L E     
Sbjct: 230  ELKTPPSSPSYRNFIDRGNYKDRRMKQLKDQLDQTETEIENEEGKTENLNYSLNEMIDLV 289

Query: 2759 EEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNH-----------LKEALSMA 2613
             E+R ALQ    S  +     + +  ++  +   + D++ H           LK+ L   
Sbjct: 290  AERRRALQELRNSQGKDEEKLKKQIAKVESEKTKIEDEIKHLQEDEEPQIKKLKDRLDET 349

Query: 2612 VDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQN 2433
                   EK+L ++    E   ++LA    R Q L    K L+   E+T  +L     Q 
Sbjct: 350  TTKTQIAEKKLGEMRKTIEDSRQKLA---QRRQNLIERRKELTNDAENTNTELQSINNQI 406

Query: 2432 KQLELEIEKLYGSLQMKQMENTLLKDG-----NEKIYDLCKLLATKSREVQGQQEGILK- 2271
            ++++ E  KL G +   Q +++  K        +K  DL  L   ++ E   ++  I K 
Sbjct: 407  QEIDSEFNKLNGLVNKVQSDHSKKKSALQEQLAQKQKDLNDLKRKQAEEKASREAEIAKI 466

Query: 2270 -----------QDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFS 2124
                        D+N    +    E+ ++  D+K++ S    K   +         ++  
Sbjct: 467  NDQLQKTMKEYNDLNQPQNVDLKNEIDQATKDLKELESRVNKKREELFGKNNQRVAELNK 526

Query: 2123 LKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQ--------AEVD 1968
            L E++   ++ +    Q +Q A ++ +  K+EL AE E  + E+ +L+         EVD
Sbjct: 527  LNEQLKSKMDEMVKADQELQSAKDEHEAKKNELKAEIESVSDEISKLKDELEVIPDFEVD 586

Query: 1967 AIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSK---NINLESQNRSLKAELHL 1797
             ++  L EL ++ + L+ E  +N  EL ++   L + + K   N +  S+ ++ K +  L
Sbjct: 587  DLKDQLNELLKEKEELEKEKIKNNDELNSSIIMLKDEIQKEKANKDKISEEKN-KRDKEL 645

Query: 1796 QAQKAFQIQEE-----RNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHV 1632
              +K+ ++Q+E      + +E+E++ L  EVE+LKS++ ++K L    +   + L  Q  
Sbjct: 646  NDEKS-KLQDELDSLQLDEIENENDQLFEEVEDLKSKVDDAKILYNDMVDKIDDLKQQRS 704

Query: 1631 EVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVS-GSRAEAMS 1455
            +V     +  +  E++     DE+  +  E ++LK E L   + ++        + +AM+
Sbjct: 705  KVE----QKYKDLEKQNKEKSDEIEKVSKEISELK-EKLDNLNQFKDNTPELHQKVDAMN 759

Query: 1454 -VLISKSLGNGRANQ------REFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFET 1296
              ++ KS  N +  +       E Q+ E +   ++++ ++   ++ ++  + ++ E  + 
Sbjct: 760  EQIVKKSQENEKIQEEMNKLNEELQHLENEMEEIEVVNDERETIQEKIDNIKQQIEEKKK 819

Query: 1295 KSREAQQMANKL----EEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTP 1128
             + E Q + N L     + Q+ L D+            R+++L ++N + R ++  ELT 
Sbjct: 820  SNEEIQDIMNLLIEAENDAQKELDDIEIVEAQSEEIRQRIQTL-QDNLQDRKKLNNELTE 878

Query: 1127 SRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKY 948
              +   +E   +K++   + D T L+              D   S  +++D + +   + 
Sbjct: 879  QNNKLQKE---LKDLQ-NELDQTELVN-------------DDSESLNKKLDEIKEQINER 921

Query: 947  WNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQ 768
             ++  + T+Q + L   +++  +                  I  + ++KQ+ E   +  Q
Sbjct: 922  KSQNENNTEQNEKLIEEIEKFAKELDEIEIIEDKSDKLQAQI--SELQKQIDEKQKNNEQ 979

Query: 767  LVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLK-----VDEEVPILCHQNSKIAERLDIN 603
              + N  L+ +++      +SM  +      LK     V++E+  +   N+K+ + L   
Sbjct: 980  TDKSNNDLEHELQITKQKLDSMSSVKNNSDYLKSEIENVNKEIEKIRDTNNKLKQELQ-- 1037

Query: 602  TDKARALD 579
             DK + L+
Sbjct: 1038 -DKNKELE 1044



 Score =  105 bits (262), Expect = 1e-19
 Identities = 147/716 (20%), Positives = 306/716 (42%), Gaps = 62/716 (8%)
 Frame = -3

Query: 3191 LQKKAGELQTKVH-IREEESCKHLTEALENHI--YGSLLESCVVDREAHIKQLMEQMNAL 3021
            LQ +  EL  +++ ++EE + +   E L+  +    + L+  + D E + K L E+++AL
Sbjct: 2604 LQSQIDELNEQINSVKEESNPQQTKENLQKELDDLNNKLQQMIEDEEENEK-LKEEIDAL 2662

Query: 3020 VKEKRELENDAQRGEEISQSLKDEVFQLKE-------------------VSRLYEEEKQH 2898
             +E ++      + +E +Q LK ++ +L+E                   +S+L  E K+ 
Sbjct: 2663 KEELKD-----NKSQEENQQLKSQISELQEQIKQKQNEISETENSLKSQISQLQNELKEK 2717

Query: 2897 TIELQENFNALRQKNEDICLKIEANNNLLEQK------DNIIVELSHKLQE----NEEQR 2748
              E  +  N+L ++ +   LK + NN  +E K       +++ +L  KLQE    NE  +
Sbjct: 2718 ESERGDKSNSLYKEIDS--LKEKINNQEIENKADSSQLSDLLKDLKKKLQELTEENETIK 2775

Query: 2747 SALQNDMQSVEQMHAVSQTEREELNRQLVLLRDD---------VNHLKEALSMAVDDRAF 2595
            S +  + +  +   A  + E++ LN++L  + DD         V+ LKE L++    +  
Sbjct: 2776 SKISEEKEKSKSEMAKLEEEKKSLNKELENVNDDEDKEMLEGEVSSLKETLNLK---KQI 2832

Query: 2594 MEKQLQDLENQKETVSKELALSVSRE-------------QKLASDLKALSEKEESTKNQL 2454
             E+Q Q L  +KE +++EL+     E             +KL +D   L E ++  K   
Sbjct: 2833 NEEQKQKLSQEKEKLTEELSQLNDNEDLKKEIEQKKEELEKLKNDSSLLQELQDLKKQIE 2892

Query: 2453 LIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGIL 2274
                +QN +L  +IE L   +  K+ EN L+      +      L  + + ++   E   
Sbjct: 2893 EKSEKQNPELLKQIEDLKKEISEKESENDLITGEKNTVEQQYNKLVEQRKYLESTMEAAK 2952

Query: 2273 KQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNIN 2094
            K+   + D   +  E+       +  N     ++   +E +   ++ +     E      
Sbjct: 2953 KK---VSDLRQQCDELSMKNNQFRIDNEKEFQEIKKSIEEIKGQREQLAKKHNE------ 3003

Query: 2093 SLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAE----VDAIQHILIELKRKNQ 1926
              R   +   +A +++ D + +L AE + + + +L++ +E    V  ++    +L++KN+
Sbjct: 3004 DKRRAREYNTLARQKLTDAQQKLDAE-KAKNENLLKMMSEQEKTVSNLEKESEDLEQKNK 3062

Query: 1925 TLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVES 1746
             L+ +          ++ ++  +  K   L+  N  L       +QK  Q  E+ N +++
Sbjct: 3063 ELEQQMTSTGD---FSQDKIEELRKKKEELQKLNDEL-------SQKQKQNIEQSNSLQN 3112

Query: 1745 EHNVLSSEVENLKSEL----KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLM 1578
            E   LS+E+E+LKS      KES ++E        I+  +  E   L+ +S +  +EK  
Sbjct: 3113 EKVTLSNEIESLKSSTEAMEKESTEMEKKLEEDKGIISEKSKEKEDLEKKS-KEQQEKSD 3171

Query: 1577 RILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQN 1398
            ++  E+  L+ +  K+  E      D   K             +  S+ N    +++ + 
Sbjct: 3172 KLKQEVAELQEKAKKITTENT----DLNDKITD----------LEISISNAERRKKDLEE 3217

Query: 1397 KEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDM 1230
            + E SS   L + +    E   +K  E  EM +   +  + + + +  ++Q +  +
Sbjct: 3218 EIEKSSAKSLQEKEKELEEIAEKKKKEVREMKKQHKQNIRSLESSISLLEQDIKSL 3273



 Score = 97.4 bits (241), Expect = 3e-17
 Identities = 186/982 (18%), Positives = 396/982 (40%), Gaps = 148/982 (15%)
 Frame = -3

Query: 3065 REAHIKQLMEQMNALVKEKRELEN--DAQRGEEISQSLKD----EVFQLKEVSRLYEEEK 2904
            REA I ++ +Q+   +KE  +L    +     EI Q+ KD    E    K+   L+ +  
Sbjct: 459  REAEIAKINDQLQKTMKEYNDLNQPQNVDLKNEIDQATKDLKELESRVNKKREELFGKNN 518

Query: 2903 QHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIV---ELSHKLQENEEQRSALQN 2733
            Q   EL +    L+ K +++   ++A+  L   KD       EL  +++   ++ S L++
Sbjct: 519  QRVAELNKLNEQLKSKMDEM---VKADQELQSAKDEHEAKKNELKAEIESVSDEISKLKD 575

Query: 2732 DMQSV-------------------EQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAV 2610
            +++ +                   E++        +ELN  +++L+D++   K       
Sbjct: 576  ELEVIPDFEVDDLKDQLNELLKEKEELEKEKIKNNDELNSSIIMLKDEIQKEKANKDKIS 635

Query: 2609 DDRAFMEKQLQDLEN--QKETVSKELALSVSREQKLASDLKALSEKEESTK---NQLLIQ 2445
            +++   +K+L D ++  Q E  S +L    +   +L  +++ L  K +  K   N ++ +
Sbjct: 636  EEKNKRDKELNDEKSKLQDELDSLQLDEIENENDQLFEEVEDLKSKVDDAKILYNDMVDK 695

Query: 2444 TEQNKQLELEIEKLYGSLQMKQMENT-LLKDGNEKIYDLCKLLATKSREVQGQQEGILKQ 2268
             +  KQ   ++E+ Y  L+ +  E +  ++  +++I +L + L   ++      E   K 
Sbjct: 696  IDDLKQQRSKVEQKYKDLEKQNKEKSDEIEKVSKEISELKEKLDNLNQFKDNTPELHQKV 755

Query: 2267 DINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSL 2088
            D   E  + +++E  +   +M K+N +    +   +E +  + D+    +E +   I+++
Sbjct: 756  DAMNEQIVKKSQENEKIQEEMNKLNEEL-QHLENEMEEIEVVNDE----RETIQEKIDNI 810

Query: 2087 RNDAQMVQVALEQMQDTKSELFAEAEIRAQ------EVLRLQAE-----VDAIQHILIEL 1941
            +   +  + + E++QD  + L  EAE  AQ      E++  Q+E     +  +Q  L + 
Sbjct: 811  KQQIEEKKKSNEEIQDIMN-LLIEAENDAQKELDDIEIVEAQSEEIRQRIQTLQDNLQDR 869

Query: 1940 KRKNQTL------------------------QDESQRNAKELWNAKARLNNVMSKNINLE 1833
            K+ N  L                         D+S+   K+L   K ++N   S+N N  
Sbjct: 870  KKLNNELTEQNNKLQKELKDLQNELDQTELVNDDSESLNKKLDEIKEQINERKSQNENNT 929

Query: 1832 SQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-----------KESK 1686
             QN  L  E+   A++  +I+    ++E + + L +++  L+ ++           K + 
Sbjct: 930  EQNEKLIEEIEKFAKELDEIE----IIEDKSDKLQAQISELQKQIDEKQKNNEQTDKSNN 985

Query: 1685 DLEGYFLRLFEIL------------LGQHVEVASLDIESCRFAEEKLM-------RILDE 1563
            DLE       + L            L   +E  + +IE  R    KL        + L+E
Sbjct: 986  DLEHELQITKQKLDSMSSVKNNSDYLKSEIENVNKEIEKIRDTNNKLKQELQDKNKELEE 1045

Query: 1562 LICLRNENAKLK----------------NEALYEYHDYERKNVSGSRAEAMSV------- 1452
            +  + + + +LK                N  + E   +  +++  + A+  S+       
Sbjct: 1046 MTDIADNSEELKEKIDSVNEEITKRVANNTTIDELIRHLHEDLKNAEAKLQSIPHVDDNT 1105

Query: 1451 -LISKSLGNGRA----NQRE-----------FQNKEE---DSSGVDLLKNKCTRLEFQVQ 1329
              + KSL    A     QRE            Q KEE   + + ++ + +K   +  +++
Sbjct: 1106 DSLQKSLDEVLAQISQKQRENDELNDEISRLIQEKEEKTDELNNMETIPDKREEISSEIE 1165

Query: 1328 ----KLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTR 1161
                ++ EK +  E  + E +++A +LE ++QTLS M             + + K+E + 
Sbjct: 1166 TVKSQIEEKKKNNEKIAEENKKLAEELENLRQTLSKMETSDQPLENIQKEIETTKQEISE 1225

Query: 1160 LRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQE 981
             + E+          K  + S   EI+   E+    I              + + SE   
Sbjct: 1226 KQKELDELKQELEQIKDEDQSKADEISEEIENIKTQIDEKNKKNEEIAKNNEEKQSE--- 1282

Query: 980  IDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGID-MNSIE 804
                +D+  K    +     +T+ +   ++E Q+                  +D +    
Sbjct: 1283 ----LDEKLKELQDLEEIKDETEEINQQIEETQKEIETKKQQKENNNKLNEELDKLKQDL 1338

Query: 803  KQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNG--QEQKLKVDEEVPILCHQNS 630
            +Q++ +  +V +L E   ++K D+       +S H LN   +E    V+EE+  L  +  
Sbjct: 1339 EQIENVEDNVEKLTEEIEKVKSDI-------DSKHQLNNDIKEANEVVEEELNSLKEELE 1391

Query: 629  KIAERLDINTDKARALDMEVQR 564
            KI E ++  +D+ R   +++Q+
Sbjct: 1392 KI-EPVEDKSDEIRKEIVKIQK 1412



 Score = 77.4 bits (189), Expect = 4e-11
 Identities = 137/676 (20%), Positives = 296/676 (43%), Gaps = 39/676 (5%)
 Frame = -3

Query: 3044 LMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQH--TI------- 2892
            L E++N L K+  E++ +  + EE+SQ + D       + +L EE+K    TI       
Sbjct: 1535 LNEELNNLQKQYDEIDVEEDKSEELSQKVTD-------LQKLLEEKKSQNETIKSGNENI 1587

Query: 2891 --ELQ------ENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQ 2736
              ELQ      +N   +   +E+   KIE    ++  K     E +   +E + Q   L+
Sbjct: 1588 LKELQSLQNELDNIEVVSSSSEEGEKKIEKLKQMISDKQKQNEETTKHNEELDNQIKDLE 1647

Query: 2735 NDMQSV-----------EQMHAVSQ--TEREELNRQLVLLRDDVNHLKEALSMAVDDRAF 2595
            N++  +           +Q+  +    T++++ N +   L   +    + L    D+ A 
Sbjct: 1648 NELNEIIPVKDKSNDLQQQIEEIKDKITDKQKKNEECSQLNTALKEEYDQLKSEFDNIAV 1707

Query: 2594 MEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELE 2415
            +E + ++++ + + +  E    + +++K   D+K  ++  E    +   + EQ + +E +
Sbjct: 1708 IESKAEEIQQKIDEIKSE----IDQKRKEYQDIKEGNDLLEEAYTEKQKELEQIEVVEDK 1763

Query: 2414 IEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELART 2235
             E L   +     +    K  N        L    S E   +Q G LKQ++N   +L +T
Sbjct: 1764 TEDLQNLIDEITEQINSRKSNN--------LERQVSNETFEKQLGQLKQELN---DLPQT 1812

Query: 2234 KEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVAL 2055
             +   ++  +K+   +   K++ + +    M D+  SL +E++  + S  ND +  +  L
Sbjct: 1813 DD---NSESLKEEIEETKKKLAMMKDEYQRMSDEDKSLTDELI-RVESELNDLENQKNVL 1868

Query: 2054 EQMQDTKSELFAEAEIRAQE---VLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELW 1884
            E      +E   +AE + Q    ++ L+ ++D ++  L    ++ +  Q++ ++  KE  
Sbjct: 1869 E------NETIVKAEKKMQNDNTIMDLRNKIDTLKAQL----QQQEKPQEDIEKLKKEYQ 1918

Query: 1883 NAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKS 1704
              K + +  +S+N    S + +   ELH   +   +I++   V + + + L S++ ++K+
Sbjct: 1919 ELKFQFDAKVSQNKEEVSHSEN---ELHSLKEMYDKIEK---VEQQQVDSLKSQILSVKA 1972

Query: 1703 ELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKN 1524
            ++ +         +  E L  +  + A  ++E    AE K+    DEL+ L  E  +LK 
Sbjct: 1973 QIDDQNKKNEEMKKQIEKLTSEKSD-AQNELEK---AENKVDP--DELVRLSEEIEELKL 2026

Query: 1523 EALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRA-NQREFQNKEEDSSGVDLLKNKCTR 1347
            EA  +    + + V  S  E +S    + L N ++ NQ +  N+ +     D +  K   
Sbjct: 2027 EA--DEKKKQNEEVRSSLEEELS-KYKEILENLKSDNQSDIHNQIDQIK--DRINEKQQE 2081

Query: 1346 LEFQVQKLSE----KAEMFETKSREAQQMANKLE-EMQQTLSDMXXXXXXXXXXXIRVRS 1182
             E   QKL E      ++ E  ++E +++  ++E E+ +   ++            +++ 
Sbjct: 2082 NEADNQKLQEIINNHKKLLENMNKEHEEIQKQIEQEVDKNNKEIDQKQKEINEVKEKLQQ 2141

Query: 1181 LKKENTRLRSEMKGEL 1134
             KKEN   + E++ ++
Sbjct: 2142 AKKENEDDKVELQRQI 2157



 Score = 69.3 bits (168), Expect = 1e-08
 Identities = 103/530 (19%), Positives = 236/530 (44%), Gaps = 17/530 (3%)
 Frame = -3

Query: 3224 QHQKILEDYY-ALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIK 3048
            + +K LE    A +KK  +L+ +    +E S K+    ++N      ++  + + +   +
Sbjct: 2939 EQRKYLESTMEAAKKKVSDLRQQC---DELSMKNNQFRIDNEKEFQEIKKSIEEIKGQRE 2995

Query: 3047 QLMEQMNALVKEKRELENDA-QRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFN 2871
            QL ++ N   +  RE    A Q+  +  Q L  E  + + + ++  E+++    L++   
Sbjct: 2996 QLAKKHNEDKRRAREYNTLARQKLTDAQQKLDAEKAKNENLLKMMSEQEKTVSNLEKESE 3055

Query: 2870 ALRQKNEDICL-----------KIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQ 2724
             L QKN+++             KIE      E+   +  ELS K ++N EQ ++LQN+  
Sbjct: 3056 DLEQKNKELEQQMTSTGDFSQDKIEELRKKKEELQKLNDELSQKQKQNIEQSNSLQNEKV 3115

Query: 2723 SVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSK 2544
            ++       ++  E + ++   +   +   K  +S    ++  +EK+ ++ + + + + +
Sbjct: 3116 TLSNEIESLKSSTEAMEKESTEMEKKLEEDKGIISEKSKEKEDLEKKSKEQQEKSDKLKQ 3175

Query: 2543 ELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTL 2364
            E+A    + +K+ ++   L++K    +  +     + K LE EIEK            + 
Sbjct: 3176 EVAELQEKAKKITTENTDLNDKITDLEISISNAERRKKDLEEEIEK------------SS 3223

Query: 2363 LKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDA 2184
             K   EK  +L ++   K +EV+  ++   +   ++E  ++  ++  +S  +++  NS  
Sbjct: 3224 AKSLQEKEKELEEIAEKKKKEVREMKKQHKQNIRSLESSISLLEQDIKSLEEIQ--NSSK 3281

Query: 2183 GAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIR 2004
             ++  G+   LL  K     +K+  L +I + R D+++ +   E ++  K       +IR
Sbjct: 3282 KSEQEGL--QLLDEKVADLKIKKFELEDIIADR-DSELKKWEKELLEKNKELSEVNRQIR 3338

Query: 2003 AQEVLRLQAEVDAIQHI--LIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLES 1830
            A +  ++    + I+ I   IE K+K   L      + +E  ++K +   + +  I+  S
Sbjct: 3339 ALKGDKIDQIKEDIKDIDEEIESKKKKLNLNTVEDNDEEEEESSKPK---IFTPTISKPS 3395

Query: 1829 QNRSLKAELHLQA--QKAFQIQEERNVVESEHNVLSSEVENLKSELKESK 1686
            +    K ++ +    ++  + +EE N  +    V+  + E  K E ++ K
Sbjct: 3396 EQEDNKPKIFVPTIPKQNEENKEENNKPKVFVPVVPKQTEEQKKEEEKPK 3445


>ref|XP_001319569.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
            gi|121902355|gb|EAY07346.1| viral A-type inclusion
            protein, putative [Trichomonas vaginalis G3]
          Length = 940

 Score =  125 bits (314), Expect = 1e-25
 Identities = 160/730 (21%), Positives = 326/730 (44%), Gaps = 26/730 (3%)
 Frame = -3

Query: 3191 LQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNALVKE 3012
            LQK+  E + K  I E E  K+    L+  I    L++   ++  ++K+  E+ N  +K+
Sbjct: 75   LQKEKEETE-KALIEENEDYKNQLSELKKQIED--LQNENEEKVENLKKENEEFNNEIKD 131

Query: 3011 KRE----LENDAQRGEEISQSLKDEVFQ-LKEVSRLYEEEKQHTIELQENFNALRQKNED 2847
             ++    L+      E+  Q    E+ Q ++++ +   +EK       E    L+QKN D
Sbjct: 132  LQDQIELLKKSMSESEDKDQKFVIELNQQIEKLKQKVSDEKDLIQVKDEEIIDLKQKNTD 191

Query: 2846 ICLKIEANNNLLEQKDNI---IVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREEL 2676
            +    E NN L E K+ +   I EL+ KL +  E+        Q + ++ +  +   ++ 
Sbjct: 192  LS---EQNNKLNEDKNELEKQIEELAQKLSDESEKEKL----KQEINELKSEKENSEKDF 244

Query: 2675 NRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDL 2496
            N++L  L   V  L++++S          +++ + E  KE +S +L       +KL+ +L
Sbjct: 245  NKKLENLTQKVTELEDSISQKT-------REIDEAETAKEDISLKLDNLAEENEKLSQNL 297

Query: 2495 KALSEK--EESTKNQLLIQTEQNKQLELE-IEKLYGSLQ---MKQMENTLLKDG--NEKI 2340
              + EK  E+ T+ + L +  ++ + E E ++K   S Q   MK+ EN   ++G   EKI
Sbjct: 298  SEIYEKLNEKVTETEKLQKENEDLKSENELLKKDSDSAQEELMKENENLKKENGEITEKI 357

Query: 2339 YDLCKLLATKSREVQGQQEGILK-QDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGI 2163
             +L K +  + + V+  ++ I +    N E+     KE+     +++++N     K    
Sbjct: 358  EELQKEIGERQKTVEDLKQKIEEINSQNAEESEKNQKEIDDLTQEIEEINQKLDEKQK-- 415

Query: 2162 LEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQ----DTKSELFAEAEIRAQE 1995
                    DD+   KE +   ++ ++ + +  Q  +E +Q    D K  +   +E + +E
Sbjct: 416  ------ENDDLKKEKENLQKEVDEIKKNFEENQNQIENLQKENDDLKKGMNQSSEEKQKE 469

Query: 1994 VLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSL 1815
            +  ++   +  Q  + +L ++N+ +  +     KE+   K ++     +N++L+ +   L
Sbjct: 470  IEEIKKNFEEKQKEIDDLTQENEEMNQKLDEKQKEIEEIKQKIEENQKQNVDLKKEVEDL 529

Query: 1814 KAELH-LQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKE-SKDLEG---YFLRLFEI 1650
              E+  L+ QK+   Q+E N V SE   L  ++E LK+E +  S +LE    +  +L   
Sbjct: 530  TQEIEKLEEQKS---QKEEN-VNSEQENLQKQIEELKNEKETISNELESKTKHNEKLVSS 585

Query: 1649 LLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSR 1470
            L     + A LDI   R  +EK + I +      N +A++++  +      E  +    +
Sbjct: 586  LQEFAKKNAELDITIERLTQEKEVLINNVNDLQNNVDAEIRDLKVKLQEKDEEIDGLNEQ 645

Query: 1469 AEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKS 1290
             E +    +        NQ+E + K++++     LK +   L  +++KL E     +   
Sbjct: 646  IEQIIKENNDLKQKQEENQKENEQKQKENED---LKKEVDDLTQEIEKLEE-----QKSQ 697

Query: 1289 REAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKH 1110
            +E + + ++ E +Q+ + ++             V   KK+N  L  E + E+        
Sbjct: 698  KEEENVNSEQENLQKQIEEL----------KKEVEQYKKQNEDLIEENE-EMDEKMKILQ 746

Query: 1109 REGSFIKEIN 1080
            ++   IKE N
Sbjct: 747  KQIEEIKETN 756



 Score =  124 bits (310), Expect = 3e-25
 Identities = 131/578 (22%), Positives = 269/578 (46%), Gaps = 28/578 (4%)
 Frame = -3

Query: 3224 QHQKILEDYYALQKKAGELQTKVHIREEESCKH---LTEALENHIYGSLLESCVVDREAH 3054
            + QK +ED   L++K  E+ ++     E++ K    LT+ +E       +   + +++  
Sbjct: 366  ERQKTVED---LKQKIEEINSQNAEESEKNQKEIDDLTQEIEE------INQKLDEKQKE 416

Query: 3053 IKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIE-LQEN 2877
               L ++   L KE  E++ + +  +   ++L+ E   LK+      EEKQ  IE +++N
Sbjct: 417  NDDLKKEKENLQKEVDEIKKNFEENQNQIENLQKENDDLKKGMNQSSEEKQKEIEEIKKN 476

Query: 2876 FNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVS 2697
            F   +++ +D+  + E  N  L++K   I E+  K++EN++Q   L+ +++ + Q     
Sbjct: 477  FEEKQKEIDDLTQENEEMNQKLDEKQKEIEEIKQKIEENQKQNVDLKKEVEDLTQ----- 531

Query: 2696 QTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSRE 2517
              E E+L  Q     ++VN  +E L          +KQ+++L+N+KET+S EL       
Sbjct: 532  --EIEKLEEQKSQKEENVNSEQENL----------QKQIEELKNEKETISNELESKTKHN 579

Query: 2516 QKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQ-MKQMENTLLKDGNEKI 2340
            +KL S L+  ++K              N +L++ IE+L    + +    N L  + + +I
Sbjct: 580  EKLVSSLQEFAKK--------------NAELDITIERLTQEKEVLINNVNDLQNNVDAEI 625

Query: 2339 YDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMK-KVNSDAGAKVSGI 2163
             DL   L  K  E+ G  E I +Q I   ++L + +E  +   + K K N D   +V  +
Sbjct: 626  RDLKVKLQEKDEEIDGLNEQI-EQIIKENNDLKQKQEENQKENEQKQKENEDLKKEVDDL 684

Query: 2162 LEMLLPMKDDVFSLKEEVLGNINS----LRNDAQMVQVALEQMQDTKSELFAEAEIRAQE 1995
             + +  +++     +EE   N+NS    L+   + ++  +EQ +    +L  E E   ++
Sbjct: 685  TQEIEKLEEQKSQKEEE---NVNSEQENLQKQIEELKKEVEQYKKQNEDLIEENEEMDEK 741

Query: 1994 VLRLQAEVDAIQH---------------ILIELKRKNQTLQDESQRNAKELWNAKARLNN 1860
            +  LQ +++ I+                + I  + K + ++ E ++N KE+   K  +  
Sbjct: 742  MKILQKQIEEIKETNEESSEQIYALKKDLEIAEQEKERIVKMEREQNMKEISQLKFEVEE 801

Query: 1859 VMSKNINLESQNR--SLKAELHLQAQKAF-QIQEERNVVESEHNVLSSEVENLKSELKES 1689
               + I+ E QN+  S+  E   + +K   +++++ N+ +S  + + S+++ + ++L   
Sbjct: 802  --KRRISEEYQNKCQSIAEEFKQREKKVLAEVEKKFNMFKSAIDKIVSKLQIVDNKLNNI 859

Query: 1688 KDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMR 1575
            K +E   +     +LG      + D+ S     EK  R
Sbjct: 860  KAIEKTVIESLAPVLGIDSTEINFDVSSITPLVEKAKR 897



 Score =  120 bits (302), Expect = 3e-24
 Identities = 144/732 (19%), Positives = 308/732 (42%), Gaps = 43/732 (5%)
 Frame = -3

Query: 2681 ELNRQLVLLRDDVNHLKEALSMAVDDRAF-----------MEKQLQDLENQKETVSKELA 2535
            E+ +Q+      +N LKE L    +++             ++KQ+ +++NQ E + KE  
Sbjct: 3    EIKKQIEEKDKQINELKEELQKQTEEKETEINELMNQIEDLQKQIDEIKNQNENLQKEKE 62

Query: 2534 LSVSREQKLASDL--------KALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQ 2379
             S++   K   DL        KAL E+ E  KNQL    +Q + L+ E E+   +L+ + 
Sbjct: 63   NSLNEMNKQIDDLQKEKEETEKALIEENEDYKNQLSELKKQIEDLQNENEEKVENLKKEN 122

Query: 2378 ME-NTLLKDGNEKIYDLCKLLATKSREVQ------GQQEGILKQDINIEDELARTK---- 2232
             E N  +KD  ++I  L K ++    + Q       QQ   LKQ ++ E +L + K    
Sbjct: 123  EEFNNEIKDLQDQIELLKKSMSESEDKDQKFVIELNQQIEKLKQKVSDEKDLIQVKDEEI 182

Query: 2231 -EVGRSATDM----KKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMV 2067
             ++ +  TD+     K+N D       I E+   + D+  S KE++   IN L+++ +  
Sbjct: 183  IDLKQKNTDLSEQNNKLNEDKNELEKQIEELAQKLSDE--SEKEKLKQEINELKSEKENS 240

Query: 2066 QVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKEL 1887
            +    +  +  ++   E E    +  R   E+D  +    ++  K   L +E+++ ++ L
Sbjct: 241  EKDFNKKLENLTQKVTELEDSISQKTR---EIDEAETAKEDISLKLDNLAEENEKLSQNL 297

Query: 1886 WNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQE----ERNVVESEHNVLSSEV 1719
                 +LN  +++   L+ +N  LK+E  L  + +   QE    E   ++ E+  ++ ++
Sbjct: 298  SEIYEKLNEKVTETEKLQKENEDLKSENELLKKDSDSAQEELMKENENLKKENGEITEKI 357

Query: 1718 ENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNEN 1539
            E L+ E+ E +       +  E +  Q+ E +  + +      +++  I  +L   + EN
Sbjct: 358  EELQKEIGERQKTVEDLKQKIEEINSQNAEESEKNQKEIDDLTQEIEEINQKLDEKQKEN 417

Query: 1538 AKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKN 1359
              LK E                  E +   + +   N   NQ + +N ++++   DL K 
Sbjct: 418  DDLKKE-----------------KENLQKEVDEIKKNFEENQNQIENLQKEND--DLKKG 458

Query: 1358 KCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSL 1179
                 E + +++ E  + FE K +E   +  + EEM Q L +             ++   
Sbjct: 459  MNQSSEEKQKEIEEIKKNFEEKQKEIDDLTQENEEMNQKLDE---KQKEIEEIKQKIEEN 515

Query: 1178 KKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTR 999
            +K+N  L+ E++         + ++    + +N   E+    I+           +++++
Sbjct: 516  QKQNVDLKKEVEDLTQEIEKLEEQKSQKEENVNSEQENLQKQIEELKNEKETISNELESK 575

Query: 998  TSETQEIDTLMDD----NRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKW 831
            T   +++ + + +    N +    +   T++ + L N+V +LQ                 
Sbjct: 576  TKHNEKLVSSLQEFAKKNAELDITIERLTQEKEVLINNVNDLQNNVDAEIRDLK------ 629

Query: 830  GGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEEVP 651
              + +   ++++  LN  + Q+++ N  LK+  +      N   +   Q++   + +EV 
Sbjct: 630  --VKLQEKDEEIDGLNEQIEQIIKENNDLKQKQE-----ENQKENEQKQKENEDLKKEVD 682

Query: 650  ILCHQNSKIAER 615
             L  +  K+ E+
Sbjct: 683  DLTQEIEKLEEQ 694



 Score =  109 bits (273), Expect = 7e-21
 Identities = 148/700 (21%), Positives = 306/700 (43%), Gaps = 85/700 (12%)
 Frame = -3

Query: 3074 VVDREAHIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLK---EVSRLYEEEK 2904
            ++D +     L EQ N L ++K ELE      EE++Q L DE  + K   E++ L  E++
Sbjct: 182  IIDLKQKNTDLSEQNNKLNEDKNELEKQI---EELAQKLSDESEKEKLKQEINELKSEKE 238

Query: 2903 QHTIELQENFNALRQK---------------------NEDICLKI----EANNNLLEQKD 2799
                +  +    L QK                      EDI LK+    E N  L +   
Sbjct: 239  NSEKDFNKKLENLTQKVTELEDSISQKTREIDEAETAKEDISLKLDNLAEENEKLSQNLS 298

Query: 2798 NIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALS 2619
             I  +L+ K+ E E+ +   ++     E +   S + +EEL ++   L+ +   + E + 
Sbjct: 299  EIYEKLNEKVTETEKLQKENEDLKSENELLKKDSDSAQEELMKENENLKKENGEITEKIE 358

Query: 2618 MAVDDRAFMEKQLQDLENQKETVSKELALSVSREQK----LASDLKALSEK--EESTKNQ 2457
                +    +K ++DL+ + E ++ + A    + QK    L  +++ +++K  E+  +N 
Sbjct: 359  ELQKEIGERQKTVEDLKQKIEEINSQNAEESEKNQKEIDDLTQEIEEINQKLDEKQKEND 418

Query: 2456 LLIQTEQNKQLELE-----IEKLYGSLQMKQMENTLLKDG--------NEKIYDLCKLLA 2316
             L + ++N Q E++      E+    ++  Q EN  LK G         ++I ++ K   
Sbjct: 419  DLKKEKENLQKEVDEIKKNFEENQNQIENLQKENDDLKKGMNQSSEEKQKEIEEIKKNFE 478

Query: 2315 TKSREVQG--QQEGILKQDIN-----IEDELARTKEVGRSATDMKKVNSDAGAKVSGILE 2157
             K +E+    Q+   + Q ++     IE+   + +E  +   D+KK   D   ++  + E
Sbjct: 479  EKQKEIDDLTQENEEMNQKLDEKQKEIEEIKQKIEENQKQNVDLKKEVEDLTQEIEKLEE 538

Query: 2156 MLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALE---------------------QMQD 2040
                 +++V S +E +   I  L+N+ + +   LE                     ++  
Sbjct: 539  QKSQKEENVNSEQENLQKQIEELKNEKETISNELESKTKHNEKLVSSLQEFAKKNAELDI 598

Query: 2039 TKSELFAEAEIRAQEVLRLQAEVDA-IQHILIELKRKNQT---LQDESQRNAKELWNAKA 1872
            T   L  E E+    V  LQ  VDA I+ + ++L+ K++    L ++ ++  KE  + K 
Sbjct: 599  TIERLTQEKEVLINNVNDLQNNVDAEIRDLKVKLQEKDEEIDGLNEQIEQIIKENNDLKQ 658

Query: 1871 RLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKE 1692
            +      +N   + +N  LK E+    Q+  +++E+++  E E+  ++SE ENL+ +++E
Sbjct: 659  KQEENQKENEQKQKENEDLKKEVDDLTQEIEKLEEQKSQKEEEN--VNSEQENLQKQIEE 716

Query: 1691 SKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALY 1512
             K     + +  E L+ ++ E+            ++ M+IL + I    E  K  NE   
Sbjct: 717  LKKEVEQYKKQNEDLIEENEEM------------DEKMKILQKQI----EEIKETNEESS 760

Query: 1511 EYHDYERKNVSGSRAEAMSVL-ISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRL--E 1341
            E     +K++  +  E   ++ + +       +Q +F+ +E+     +  +NKC  +  E
Sbjct: 761  EQIYALKKDLEIAEQEKERIVKMEREQNMKEISQLKFEVEEKRRISEE-YQNKCQSIAEE 819

Query: 1340 FQVQK---LSEKAEMFETKSREAQQMANKLEEMQQTLSDM 1230
            F+ ++   L+E  + F        ++ +KL+ +   L+++
Sbjct: 820  FKQREKKVLAEVEKKFNMFKSAIDKIVSKLQIVDNKLNNI 859


>ref|XP_816749.1| hypothetical protein [Trypanosoma cruzi strain CL Brener]
            gi|70881897|gb|EAN94898.1| hypothetical protein,
            conserved [Trypanosoma cruzi]
          Length = 1238

 Score =  124 bits (311), Expect = 3e-25
 Identities = 161/761 (21%), Positives = 334/761 (43%), Gaps = 32/761 (4%)
 Frame = -3

Query: 3068 DREAHIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIE 2889
            D+   ++++ EQ   L   +R+LE      EE+    +D+   L+EVS   E+ ++   E
Sbjct: 11   DKTRGLQEVSEQAEDL---QRQLEELRAENEELRVEHEDKTRGLQEVSEQAEDLQRQLEE 67

Query: 2888 LQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQND---MQSV 2718
            L+     LR ++ED   K      + EQ +++  +L     ENEE R+  ++    +Q V
Sbjct: 68   LRAENEELRAEHED---KTRGLQEVSEQAEDLQRQLEELRAENEELRAEDEHKTRGLQEV 124

Query: 2717 EQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKEL 2538
             +     Q + EEL  +   LR +       L    +    +++QL++L  + E +  E 
Sbjct: 125  SEQAEDLQRQLEELRAENEELRGEYEDKTRGLQEVSEQAEDLQRQLEELRAENEELRGE- 183

Query: 2537 ALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQ---------M 2385
                   +     L+ +SE+ E  + QL     +N++L  E E     LQ          
Sbjct: 184  ------HEDKTRGLQEVSEQAEDLQRQLEELRAENEELRAEHEDKTRGLQEVSEQAEDLQ 237

Query: 2384 KQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQ--DINIEDELARTKEVGRSAT 2211
            +Q+E   L+  NE++    +      +EV  Q E + +Q  ++ +E+E  R ++ G+ A 
Sbjct: 238  RQLEE--LRAENEELRGEDENKTRGLQEVSEQAEDLQRQLEELRVENEELRAEDEGK-AC 294

Query: 2210 DMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKS 2031
             ++++ S+    +   LE L    +++    E     +  +   A+ +Q  LE+++    
Sbjct: 295  GLQEL-SEQAEDLQRQLEELRAENEELRGEHEHKTRGLQEVSEQAEDLQRQLEELRVENE 353

Query: 2030 ELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMS 1851
            EL AE E + + +  +  + + +Q  L EL+ +N+ L+ E +   + L     +  ++  
Sbjct: 354  ELRAEHENKTRGLQEVSEQAEDLQRQLEELRAENEELRAEDEHKTRGLQEVSEQAEDLQR 413

Query: 1850 KNINLESQNRSLKAE-------LHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKE 1692
            +   L ++N  L+AE       L   +++A  +Q +   + +E+  L +E EN    L+E
Sbjct: 414  RLEELRAENEELRAEDEHKTRGLQELSEQAEDLQRQLEELRAENEELRAEDENKTRGLRE 473

Query: 1691 SKDLEGYFLRLFEILLGQHVEVASLDIESCRFAE------EKLMRILDELICLRNENAKL 1530
              +      R  E L  ++ E+ +      R  +      E L R L+E   LR EN +L
Sbjct: 474  VSEQAEDLQRQLEELRAENEELRAEHEHKTRGLQEVSEQAEDLQRQLEE---LRAENEEL 530

Query: 1529 KNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSS-GVDLLKNKC 1353
            + E     H+++ + +     +A    + + L   RA   E + ++E  + G+  +  + 
Sbjct: 531  RGE-----HEHKTRGLREVSEQAED--LQRRLEELRAENEELRAEDEHKTRGLREVSEQA 583

Query: 1352 TRLEFQVQKL-SEKAEM---FETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVR 1185
              L+ Q+++L +E  E+    E K+R  ++++ + E++Q+ L ++             +R
Sbjct: 584  EDLQRQLEELRAENEELRGEHEHKTRGLREVSEQAEDLQRQLEEL-------RAENEELR 636

Query: 1184 SLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKID 1005
            +  +  TR   E+  +    +       +  +E+   DE  T  +Q           +++
Sbjct: 637  AEDEHKTRGLREVSEQAEDLQRQLEELRAENEELRAEDEHKTRGLQEVSEQAEDLQRRLE 696

Query: 1004 TRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQ 882
               +E +E+    +D  K    +   ++Q + LQ  ++EL+
Sbjct: 697  ELRAENEELRA--EDEHK-TRGLQEVSEQAEDLQRQLEELR 734



 Score =  120 bits (302), Expect = 3e-24
 Identities = 158/746 (21%), Positives = 325/746 (43%), Gaps = 56/746 (7%)
 Frame = -3

Query: 3218 QKILEDYYALQKKAGELQTK---VHIREEESCKHLTEALENHIYGSLLESCVVDREAHIK 3048
            Q++ E    LQ++  EL+ +   + +  E+  + L E              V ++   ++
Sbjct: 17   QEVSEQAEDLQRQLEELRAENEELRVEHEDKTRGLQE--------------VSEQAEDLQ 62

Query: 3047 QLMEQMNALVKEKRELENDAQRG-EEISQSLKDEVFQLKEV--------------SRLYE 2913
            + +E++ A  +E R    D  RG +E+S+  +D   QL+E+              +R  +
Sbjct: 63   RQLEELRAENEELRAEHEDKTRGLQEVSEQAEDLQRQLEELRAENEELRAEDEHKTRGLQ 122

Query: 2912 EEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQE----NEEQRS 2745
            E  +   +LQ     LR +NE++  + E     L++      +L  +L+E    NEE R 
Sbjct: 123  EVSEQAEDLQRQLEELRAENEELRGEYEDKTRGLQEVSEQAEDLQRQLEELRAENEELRG 182

Query: 2744 ALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLK-------EALSMAVDDRAFMEK 2586
              ++  + ++++      + E+L RQL  LR +   L+         L    +    +++
Sbjct: 183  EHEDKTRGLQEV----SEQAEDLQRQLEELRAENEELRAEHEDKTRGLQEVSEQAEDLQR 238

Query: 2585 QLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIE- 2409
            QL++L  + E +  E       ++     L+ +SE+ E  + QL     +N++L  E E 
Sbjct: 239  QLEELRAENEELRGE-------DENKTRGLQEVSEQAEDLQRQLEELRVENEELRAEDEG 291

Query: 2408 KLYGSLQMKQMENTL------LKDGNEKIYDLCKLLATKSREVQGQQEGILKQ--DINIE 2253
            K  G  ++ +    L      L+  NE++    +      +EV  Q E + +Q  ++ +E
Sbjct: 292  KACGLQELSEQAEDLQRQLEELRAENEELRGEHEHKTRGLQEVSEQAEDLQRQLEELRVE 351

Query: 2252 DELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQ 2073
            +E  R +   ++   +++V S+    +   LE L    +++ +  E     +  +   A+
Sbjct: 352  NEELRAEHENKT-RGLQEV-SEQAEDLQRQLEELRAENEELRAEDEHKTRGLQEVSEQAE 409

Query: 2072 MVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAK 1893
             +Q  LE+++    EL AE E + + +  L  + + +Q  L EL+ +N+ L+ E +   +
Sbjct: 410  DLQRRLEELRAENEELRAEDEHKTRGLQELSEQAEDLQRQLEELRAENEELRAEDENKTR 469

Query: 1892 ELWNAKARLNNVMSKNINLESQNRSLKAE-------LHLQAQKAFQIQEERNVVESEHNV 1734
             L     +  ++  +   L ++N  L+AE       L   +++A  +Q +   + +E+  
Sbjct: 470  GLREVSEQAEDLQRQLEELRAENEELRAEHEHKTRGLQEVSEQAEDLQRQLEELRAENEE 529

Query: 1733 LSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAE------EKLMRI 1572
            L  E E+    L+E  +      R  E L  ++ E+ + D    R         E L R 
Sbjct: 530  LRGEHEHKTRGLREVSEQAEDLQRRLEELRAENEELRAEDEHKTRGLREVSEQAEDLQRQ 589

Query: 1571 LDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKE 1392
            L+E   LR EN +L+ E     H+++ + +     +A    + + L   RA   E + ++
Sbjct: 590  LEE---LRAENEELRGE-----HEHKTRGLREVSEQAED--LQRQLEELRAENEELRAED 639

Query: 1391 EDSS-GVDLLKNKCTRLEFQVQKLSEKAEMF----ETKSREAQQMANKLEEMQQTLSDMX 1227
            E  + G+  +  +   L+ Q+++L  + E      E K+R  Q+++ + E++Q+      
Sbjct: 640  EHKTRGLREVSEQAEDLQRQLEELRAENEELRAEDEHKTRGLQEVSEQAEDLQR------ 693

Query: 1226 XXXXXXXXXXIRVRSLKKENTRLRSE 1149
                       R+  L+ EN  LR+E
Sbjct: 694  -----------RLEELRAENEELRAE 708



 Score = 98.2 bits (243), Expect = 2e-17
 Identities = 132/604 (21%), Positives = 260/604 (43%), Gaps = 51/604 (8%)
 Frame = -3

Query: 3218 QKILEDYYALQKKAGELQTK-VHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQL 3042
            Q++ E    LQ++  EL+ +   +R E   K  T  L+           V ++   +++ 
Sbjct: 157  QEVSEQAEDLQRQLEELRAENEELRGEHEDK--TRGLQE----------VSEQAEDLQRQ 204

Query: 3041 MEQMNALVKEKRELENDAQRG-EEISQSLKDEVFQLKEV--------------SRLYEEE 2907
            +E++ A  +E R    D  RG +E+S+  +D   QL+E+              +R  +E 
Sbjct: 205  LEELRAENEELRAEHEDKTRGLQEVSEQAEDLQRQLEELRAENEELRGEDENKTRGLQEV 264

Query: 2906 KQHTIELQENFNALRQKNEDICLKIEAN----NNLLEQKDNIIVELSHKLQENEEQRSAL 2739
             +   +LQ     LR +NE++  + E        L EQ +++  +L     ENEE R   
Sbjct: 265  SEQAEDLQRQLEELRVENEELRAEDEGKACGLQELSEQAEDLQRQLEELRAENEELRGEH 324

Query: 2738 QNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLK-------EALSMAVDDRAFMEKQL 2580
            ++  + ++++      + E+L RQL  LR +   L+         L    +    +++QL
Sbjct: 325  EHKTRGLQEV----SEQAEDLQRQLEELRVENEELRAEHENKTRGLQEVSEQAEDLQRQL 380

Query: 2579 QDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLY 2400
            ++L  + E +  E       ++     L+ +SE+ E  + +L     +N++L  E E   
Sbjct: 381  EELRAENEELRAE-------DEHKTRGLQEVSEQAEDLQRRLEELRAENEELRAEDEHKT 433

Query: 2399 GSLQ---------MKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQ--DINIE 2253
              LQ          +Q+E   L+  NE++    +      REV  Q E + +Q  ++  E
Sbjct: 434  RGLQELSEQAEDLQRQLEE--LRAENEELRAEDENKTRGLREVSEQAEDLQRQLEELRAE 491

Query: 2252 DELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQ 2073
            +E  R  E       +++V S+    +   LE L    +++    E     +  +   A+
Sbjct: 492  NEELRA-EHEHKTRGLQEV-SEQAEDLQRQLEELRAENEELRGEHEHKTRGLREVSEQAE 549

Query: 2072 MVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAK 1893
             +Q  LE+++    EL AE E + + +  +  + + +Q  L EL+ +N+ L+ E +   +
Sbjct: 550  DLQRRLEELRAENEELRAEDEHKTRGLREVSEQAEDLQRQLEELRAENEELRGEHEHKTR 609

Query: 1892 ELWNAKARLNNVMSKNINLESQNRSLKAE-------LHLQAQKAFQIQEERNVVESEHNV 1734
             L     +  ++  +   L ++N  L+AE       L   +++A  +Q +   + +E+  
Sbjct: 610  GLREVSEQAEDLQRQLEELRAENEELRAEDEHKTRGLREVSEQAEDLQRQLEELRAENEE 669

Query: 1733 LSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAE------EKLMRI 1572
            L +E E+    L+E  +      R  E L  ++ E+ + D    R  +      E L R 
Sbjct: 670  LRAEDEHKTRGLQEVSEQAEDLQRRLEELRAENEELRAEDEHKTRGLQEVSEQAEDLQRQ 729

Query: 1571 LDEL 1560
            L+EL
Sbjct: 730  LEEL 733


>ref|XP_003405305.1| PREDICTED: early endosome antigen 1 [Loxodonta africana]
          Length = 1411

 Score =  124 bits (310), Expect = 3e-25
 Identities = 176/808 (21%), Positives = 343/808 (42%), Gaps = 29/808 (3%)
 Frame = -3

Query: 3218 QKILEDYYA-LQKKAGE------LQTKVHIREEESCKHLTEALENHIYGSL-----LESC 3075
            +K  ED YA +Q   GE      LQ K H  +E+  + LTE L+N           L   
Sbjct: 543  EKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQ-LTEKLKNQSESHKQAQENLHDQ 601

Query: 3074 VVDREAHIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQ-H 2898
            V +++AH++   + + +L     EL++     +E    L  ++    E+    E  K   
Sbjct: 602  VQEQKAHLRAAQDHVLSLETSVNELKSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQ 661

Query: 2897 TIELQENF----NALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQND 2730
              +LQ +     NAL+ K +++       N +  Q    + +++ KLQ+ +E  S L++ 
Sbjct: 662  RADLQNHLDTAQNALQDKQQEL-------NKISTQ----LAQVTKKLQDKQEHCSQLESH 710

Query: 2729 MQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETV 2550
            ++  ++ H   + + EEL  Q+  L  D   +K +   A+ D     +   DLE +   +
Sbjct: 711  LKEYKEKHLSLEQKTEELEGQVKKLEADTVEVKASKEQALQDLQQQRQLSSDLELRATEL 770

Query: 2549 SKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMEN 2370
            SK+L +          DL+  SE  E+TK  L  Q E+   L+ EIE L          N
Sbjct: 771  SKQLEMERETVSSTKLDLQKKSEALENTKQMLTKQEEETVILKQEIENL----------N 820

Query: 2369 TLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKE-VGRSATDMKKVN 2193
               K  ++++ D  +  AT+ ++V+ ++E ++K+    +++L+   + +  S ++++K N
Sbjct: 821  QDAKIQHQELNDRIQAAATELKKVKMEKETLIKELSATKEKLSEVSDSLKNSKSELEKEN 880

Query: 2192 SDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEA 2013
                   + ILE+    K+    LK ++   + +   +   ++ +LEQ ++T  +L  E 
Sbjct: 881  QKG---KTAILELEKTCKE----LKHQLQVQMETTLKEQNELKKSLEQEKETSRQLKLEV 933

Query: 2012 EIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLE 1833
                ++V+R Q  +   +    +L+   + L+  S++  K++   +  +   +S+   LE
Sbjct: 934  NSMQEQVVRAQNTLKQKEKEEQQLQGNIKELKQLSEQKKKQIEALQGEIKIAVSEKTELE 993

Query: 1832 SQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFE 1653
            ++   L+ +L    Q A Q+  E+  +    N      ENLK    +    E   L   +
Sbjct: 994  NK---LQQQL---TQAAHQLTAEKEKISVLQNTFEKSQENLKQLRSDFYGKESELLATRQ 1047

Query: 1652 IL--LGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVS 1479
             L  + + + +A  D+ S R   E   + + +   L+   A L+ E+  +    + +  +
Sbjct: 1048 DLKSVEEKLSLAQEDLISNRSQIENQKKSIQD---LKTAKATLEQESAKKEQQLKEQCKA 1104

Query: 1478 GSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFE 1299
                +    LI K L N            E S  V++ + KC R E ++ KLSE+    +
Sbjct: 1105 LQDIKKEKSLIEKELVN------------EKSKWVEIEEIKC-RQEKEIAKLSEE---LK 1148

Query: 1298 TKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEM--KGELTPS 1125
            +  +E+ +    L++ +Q L                    +K+N ++  E   K E    
Sbjct: 1149 SHKQESIKEVTSLKDAKQLLIQQKLELQGKVDTLKTTLEQEKKNQQVLKEQVKKEEDELK 1208

Query: 1124 RSFKHREG---SFIKEINIG----DEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLM 966
            + F  +E    S IKE  +G    +E++  L                  T+  + + T+ 
Sbjct: 1209 KEFAEKEAKLRSEIKEKEVGIKKHEENEAKLTMQI--------------TALNENLGTVK 1254

Query: 965  DDNRKYWNRVSHFTKQTQSLQNSVQELQ 882
             + +    RVS   KQT  L+  +  L+
Sbjct: 1255 KEWQSSQRRVSELEKQTDDLRGEIAVLE 1282



 Score = 97.4 bits (241), Expect = 3e-17
 Identities = 136/737 (18%), Positives = 311/737 (42%), Gaps = 76/737 (10%)
 Frame = -3

Query: 3218 QKILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLM 3039
            QK+      L +K   L  K+  +E +  +   +  E  +    +++ +  ++   +QL 
Sbjct: 291  QKLKSSVNELTQKNQNLTEKLLKKELDYTQLEEKYNEESVSKKNIQASLHQKDLDCQQLQ 350

Query: 3038 EQMNALVKEKRELENDAQRGEEISQSLKDEVF-----------QLKEVSRLYEEEKQHTI 2892
             +++A     + ++ +     E +Q LK+E+            + K++ +  EE++QH +
Sbjct: 351  SRLSASESSLQRMQAELGEKGEATQKLKEELSDVETKYQHLKAEFKQLQQQREEKEQHGL 410

Query: 2891 ELQENFNALR--------------------------------QKNEDICLKIEANNNLLE 2808
            +LQ   N L                                 Q+  D+ LK+      L+
Sbjct: 411  QLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLK 470

Query: 2807 QKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKE 2628
            +K     EL H+L++ ++Q    Q   QS       +Q + E++ RQ+      + +L+ 
Sbjct: 471  EKVTNSTELQHQLEKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEA 530

Query: 2627 ALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLI 2448
             L  + ++ + +EK+ +DL  + +    E A+    ++K  +  + +++  E  KNQ   
Sbjct: 531  LLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSES 590

Query: 2447 QTEQNKQLELEIEKLYGSLQMKQ-----MENTL------LKDGNEKIYDLCKLLATKSRE 2301
              +  + L  ++++    L+  Q     +E ++      L +  EK+  L   +  K+  
Sbjct: 591  HKQAQENLHDQVQEQKAHLRAAQDHVLSLETSVNELKSQLNESKEKVSQLDIQIKAKTEL 650

Query: 2300 VQGQQEGILKQDINIEDEL--------ARTKEVGRSATDMKKVN---SDAGAKVSGILEM 2154
            +   +     Q  ++++ L         + +E+ + +T + +V     D     S +   
Sbjct: 651  LLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKISTQLAQVTKKLQDKQEHCSQLESH 710

Query: 2153 LLPMKDDVFSLK---EEVLGNINSLRNDAQMVQVALEQ-MQDTKS--ELFAEAEIRAQEV 1992
            L   K+   SL+   EE+ G +  L  D   V+ + EQ +QD +   +L ++ E+RA E+
Sbjct: 711  LKEYKEKHLSLEQKTEELEGQVKKLEADTVEVKASKEQALQDLQQQRQLSSDLELRATEL 770

Query: 1991 LR-LQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSL 1815
             + L+ E + +    ++L++K++ L++  Q   K+          + + N + + Q++ L
Sbjct: 771  SKQLEMERETVSSTKLDLQKKSEALENTKQMLTKQEEETVILKQEIENLNQDAKIQHQEL 830

Query: 1814 KAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESK-DLEGYFLRLFEILLGQ 1638
               +   A +  +++ E+  +  E +    ++  +   LK SK +LE            Q
Sbjct: 831  NDRIQAAATELKKVKMEKETLIKELSATKEKLSEVSDSLKNSKSELEKE---------NQ 881

Query: 1637 HVEVASLDIE-SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEA 1461
              + A L++E +C+  + +L   ++  +  +NE   LK     E     +  +  +  + 
Sbjct: 882  KGKTAILELEKTCKELKHQLQVQMETTLKEQNE---LKKSLEQEKETSRQLKLEVNSMQE 938

Query: 1460 MSVLISKSLGNGRANQREFQ-NKEEDSSGVDLLKNKCTRLEFQVQ-KLSEKAEMFETKSR 1287
              V    +L      +++ Q N +E     +  K +   L+ +++  +SEK E+     +
Sbjct: 939  QVVRAQNTLKQKEKEEQQLQGNIKELKQLSEQKKKQIEALQGEIKIAVSEKTELENKLQQ 998

Query: 1286 EAQQMANKLEEMQQTLS 1236
            +  Q A++L   ++ +S
Sbjct: 999  QLTQAAHQLTAEKEKIS 1015


>ref|XP_001323102.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
            gi|121905960|gb|EAY10879.1| viral A-type inclusion
            protein, putative [Trichomonas vaginalis G3]
          Length = 4057

 Score =  124 bits (310), Expect = 3e-25
 Identities = 147/697 (21%), Positives = 312/697 (44%), Gaps = 43/697 (6%)
 Frame = -3

Query: 3206 EDYYALQKKAGELQTKVHIREEESCKHLTEALE-------NHIYGSLLESCVVDREAHIK 3048
            E+  +  +    LQ K++  E ES  +  +  E       N +  + L++ V   E   K
Sbjct: 1588 EEIKSKDENLNNLQNKINNYENESKTNNEKIKEMEGKQKSNELQINDLQNNVSQTENENK 1647

Query: 3047 QL---MEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQEN 2877
            QL   +E++   +K K +  N+ Q  E  SQS +   FQ      L E + + T  L++ 
Sbjct: 1648 QLKSELEKLQTEIKSKSDQLNEIQN-ESKSQSEQIVTFQ----GELKELQNKLTSSLKQ- 1701

Query: 2876 FNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSA-------LQNDMQSV 2718
             + L+++NE    +++  +  L+     I EL  K+ + EE+  +       LQN + + 
Sbjct: 1702 IDELQKENESFQKELQTRDQNLDDSHKQIEELQAKIDQYEEEIKSKDENLNNLQNKINNY 1761

Query: 2717 EQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKEL 2538
            E     +  + +E+  +       +N L+  +S   ++   ++ +L+ L+ + ++ S +L
Sbjct: 1762 ENESKTNNEKIKEMEGKQKSNELQINDLQNNVSQTENENKQLKSELEKLQTEIKSKSDQL 1821

Query: 2537 ALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLK 2358
                +  +  +  +    ++ +S   +L  Q EQ K+LE ++ +L  SL+ K      L 
Sbjct: 1822 NEIQNESKSQSEQIVTFQDEVKSKDEKLQTQEEQIKELENKLNELENSLRNKGDLQVQLN 1881

Query: 2357 DGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGA 2178
            D  +++ +L K+     ++V+  Q       +N E    +  E     T++++ N+D   
Sbjct: 1882 DREKELNNLKKVNENLVKQVEDLQ-------VNKEQSDKKLSENDEELTNLRRNNADLKK 1934

Query: 2177 KVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQ 1998
            +   + E     + ++ SL+  +    NS  ++   V+  LE+      +  A+ E+  Q
Sbjct: 1935 QNEKLRENKEKNESEIISLQNRLSELTNSHNDELFTVKRKLEENNSIVKQQNAKIEMLKQ 1994

Query: 1997 EVLRLQAEVDAIQHILIE----------LKRKNQTL----QDESQRNAKELWNAKARLNN 1860
            +++     ++ +Q I+ E          LK +N TL    QD   +N K   +  +++N+
Sbjct: 1995 QLIDQNKTIEDLQKIINESENLQFLVSTLKTENNTLKKVTQDNDLQNKKTNEDLLSQIND 2054

Query: 1859 VMSKNINLESQNRSLKAEL-----HLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELK 1695
            + +K    E  ++  K++       +Q++    I++  ++++   N L +  E L+   K
Sbjct: 2055 LQNKLKETEKSSQIQKSKYESQLNEIQSKLNQSIKDNSDLMDKHENELKNLDEKLQESQK 2114

Query: 1694 ESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEAL 1515
            +  DLE  F    ++L            E+ +  +EK  + L+EL  +++EN KLK    
Sbjct: 2115 QKNDLEKKFEMNSKLL-----------NENNKLRQEKFDKTLEELTNVKSENGKLKE--- 2160

Query: 1514 YEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLK---NKCTRL 1344
             +  D E++         M++L++ +  N   + +  Q K   ++ +D LK   N    L
Sbjct: 2161 -QIDDLEKEK------NEMTILLNTTQNNQNEDLQNLQKKL--NATIDELKMTTNDYNSL 2211

Query: 1343 EFQVQKLSEKAE----MFETKSREAQQMANKLEEMQQ 1245
            + + +KL+ K++    +  +  RE  +M N L++ Q+
Sbjct: 2212 KEKFEKLNGKSDNDNSLISSLKRENDKMKNDLQKTQE 2248



 Score =  113 bits (283), Expect = 5e-22
 Identities = 183/956 (19%), Positives = 411/956 (42%), Gaps = 75/956 (7%)
 Frame = -3

Query: 3215 KILEDYYALQKKAGELQTKVHIREEESCK-----HLTEALENHIYGSLLE--SCVVDREA 3057
            K LE+   ++ + G+L+ ++   E+E  +     + T+  +N    +L +  +  +D   
Sbjct: 2143 KTLEELTNVKSENGKLKEQIDDLEKEKNEMTILLNTTQNNQNEDLQNLQKKLNATIDE-- 2200

Query: 3056 HIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLK-EVSRLYEEEKQHTIELQE 2880
             +K      N+L ++  +L   +     +  SLK E  ++K ++ +  EE K   ++L E
Sbjct: 2201 -LKMTTNDYNSLKEKFEKLNGKSDNDNSLISSLKRENDKMKNDLQKTQEENKSLVLKLNE 2259

Query: 2879 N---FNALRQKNEDICLK---IEANNNLLEQKDNIIVE--LSHKLQENEEQR--SALQND 2730
            N    + L++ N++I  K   +E  N  L+   N + E   +++   NE++R  S LQ  
Sbjct: 2260 NEKTISKLQKTNDEISRKLTFVETENGELKLTVNEMDEKVTTNETNSNEKERLISNLQKQ 2319

Query: 2729 MQSVEQMHAVSQTEREELNRQLVL---LRDDVNHLKEALSMAVDDRAFMEKQLQDLENQK 2559
             + +E  +   Q+E + L     +   ++  +N  ++ +S   D++  ++ ++   ++  
Sbjct: 2320 NKQLENENKTLQSEIKSLQTDEFVKDQMKKQLNDYEQKVSKLEDEKRQLQNEMTKYKDDN 2379

Query: 2558 ETVSKELALSVSREQKLASDLKALSEKEESTKN----QLLIQTEQNKQLELEIEKLYGSL 2391
             T+ K L       QKL + ++ L+E +++ K     +L    E+N+Q + E++ L    
Sbjct: 2380 STMKKVLTKQEKIIQKLNTKVEDLTETKQTMKQTQSEELSSLEEENEQKKEELKHLKEEF 2439

Query: 2390 QMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSAT 2211
              K+     LK   + I  + + + ++  E++  ++  L  D  I +  +   E  +   
Sbjct: 2440 LEKEKR---LKGLEKSIQKVTEKITSQKEEIENLRKQKLIDDNTISELKSSISENEKELE 2496

Query: 2210 DMKKVNSDAGAKVSGILEMLLPMKDDV-FSLKEEVLGNINSLRNDAQMVQVALEQMQDTK 2034
            +++K +SD     S I+E L    +++  SLK       ++  N+   +Q  ++++ D  
Sbjct: 2497 NLRKSDSDK----SDIIEQLKSESENLSMSLKSR-----SNYENELTKLQNKIQKLNDQI 2547

Query: 2033 SELFAEAEIRAQEVL--RLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNN 1860
            S+   E +++++E+L  +LQ +V   +    E ++ N+T++DE+   + +L   +  LN+
Sbjct: 2548 SD--KEDDLKSKEILLEKLQKKVQETEEKFSETQKLNKTMKDENANISNQLRALQMELNS 2605

Query: 1859 VMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL----KE 1692
               +   L   N +LK ++ +   K     ++    E +   L ++  NLK ++    + 
Sbjct: 2606 KTKQIEKLVKDNTNLKEKVTILEFKQSNFDDDNKEKEEKIENLENDNFNLKKQIILNEEY 2665

Query: 1691 SKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNE--- 1521
             K ++    ++ ++      +V  L  E+    + K ++   EL  ++ E   L++E   
Sbjct: 2666 KKQIDELKFQISQLNYDNKEKVTRLQNEN-TLLKTKSLQNKSELNTVKKEREDLQSEIEE 2724

Query: 1520 --ALYEYHDYERKNVSGSRAE---------AMSVLISKSLGNGRAN-----------QRE 1407
                ++    E +N+     E         +  + + K + N +             + E
Sbjct: 2725 LKMKFDLEQKENENLKKQNKEIKNQFETTKSEKIYLEKDISNAKTELNDLLDKNNKLESE 2784

Query: 1406 FQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKL----EEMQQTL 1239
             + KE + + +   +NK   L+ ++ KL  K+EM + K+ E ++++N+L    EE+    
Sbjct: 2785 LRKKEREITRLSYSENKLNDLQIELNKL--KSEM-KDKTSEIERLSNELSLKSEEIYSFS 2841

Query: 1238 SDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFI-----KEINIG 1074
                           +++SL+ E  +++ E   E       +  E S I     KE    
Sbjct: 2842 CSSNSFEKEIQTKSDKIKSLENEIKKVQKE--NEQIKDLENQLNEKSLIIENLQKEFKQK 2899

Query: 1073 DEDDTPLIQXXXXXXXXXXXKIDT-----RTSE--TQEIDTLMDDNRKYWNRVSHFTKQT 915
            DE    ++             +       R +E  T++ + +   N+K         ++ 
Sbjct: 2900 DEKHETVLNSMNDKMKGLQNDLSVLSDLQRENEKITKQNEEIKSQNKKLKEENDDKNREI 2959

Query: 914  QSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEK--QLKELNIHVMQLVEHNTRLK 741
            + L N++Q+                   G I+MN+++   Q KE  I   + +   T+ +
Sbjct: 2960 KKLSNTLQK-------------------GDIEMNTLKDLLQTKEEKIRNYEDILEKTKTQ 3000

Query: 740  KDVKFGFAWANSMHDLNGQEQKLKVDEEVPILCHQNSKIAERLDINTDKARALDME 573
             + K  + ++ ++ D N +  +L+ + E   L          LD  T+K+++ D E
Sbjct: 3001 MEDK-NYEFSKTVKDQNDKINQLEKELEQRDL---------ELDDLTNKSKSFDDE 3046



 Score =  113 bits (283), Expect = 5e-22
 Identities = 185/982 (18%), Positives = 405/982 (41%), Gaps = 105/982 (10%)
 Frame = -3

Query: 3191 LQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNALVKE 3012
            +  K  +L++K  I  E+  K + E  E       L   + D  A+I     Q+ AL  E
Sbjct: 2547 ISDKEDDLKSK-EILLEKLQKKVQETEEKFSETQKLNKTMKDENANISN---QLRALQME 2602

Query: 3011 KRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNALRQKNEDICLKI 2832
                    ++  + + +LK++V  L+     ++++ +   E +E    L   N ++  +I
Sbjct: 2603 LNSKTKQIEKLVKDNTNLKEKVTILEFKQSNFDDDNK---EKEEKIENLENDNFNLKKQI 2659

Query: 2831 EANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLR 2652
              N    +Q D +  ++S    +N+E+ + LQN+   ++     +++E   + ++   L+
Sbjct: 2660 ILNEEYKKQIDELKFQISQLNYDNKEKVTRLQNENTLLKTKSLQNKSELNTVKKEREDLQ 2719

Query: 2651 DDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKE---LALSVSREQKLASDLKALSE 2481
             ++  LK    +   +   ++KQ ++++NQ ET   E   L   +S  +   +DL   + 
Sbjct: 2720 SEIEELKMKFDLEQKENENLKKQNKEIKNQFETTKSEKIYLEKDISNAKTELNDLLDKNN 2779

Query: 2480 KEES--------------TKNQLL-IQTEQNK-----------------QLELEIEKLYG 2397
            K ES              ++N+L  +Q E NK                 +L L+ E++Y 
Sbjct: 2780 KLESELRKKEREITRLSYSENKLNDLQIELNKLKSEMKDKTSEIERLSNELSLKSEEIYS 2839

Query: 2396 ---------------SLQMKQMENTLLK--DGNEKIYDLCKLLATKSREVQGQQEGI--- 2277
                           S ++K +EN + K    NE+I DL   L  KS  ++  Q+     
Sbjct: 2840 FSCSSNSFEKEIQTKSDKIKSLENEIKKVQKENEQIKDLENQLNEKSLIIENLQKEFKQK 2899

Query: 2276 -----------------LKQDINIEDELAR--------TKEVGRSATDMKKVNSDAGAKV 2172
                             L+ D+++  +L R         +E+      +K+ N D   ++
Sbjct: 2900 DEKHETVLNSMNDKMKGLQNDLSVLSDLQRENEKITKQNEEIKSQNKKLKEENDDKNREI 2959

Query: 2171 SGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEV 1992
              +   L     ++ +LK+ +      +RN   +++    QM+D   E     + +  ++
Sbjct: 2960 KKLSNTLQKGDIEMNTLKDLLQTKEEKIRNYEDILEKTKTQMEDKNYEFSKTVKDQNDKI 3019

Query: 1991 LRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLK 1812
             +L+ E++     L +L  K+++  DE             ++ ++ ++N NL+ +NR+LK
Sbjct: 3020 NQLEKELEQRDLELDDLTNKSKSFDDEK----------NDKIQSLTTENKNLKKENRTLK 3069

Query: 1811 AELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHV 1632
              ++   + + +++E    +ES+    SS +     EL+E K+ E   L+       + +
Sbjct: 3070 GIINSVKKSSNELEERIRNLESQLKSHSSSL----IELQEKKETEISKLQKEIDEREEKI 3125

Query: 1631 EVASLDIESCRFAEEKLMRILDELICLRN-------ENAKLKNEALYEYHDYERKNVSGS 1473
            +  +  + +CR   EK  + ++E+    N       +  K + E L E    + K+++  
Sbjct: 3126 KSQNEKLSNCRKEVEKTKQEIEEMKAKLNSQLTEEIQTIKGEKEDLLE----KIKSINKE 3181

Query: 1472 RAEAMSVLISKSLGNGRANQR---EFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEK---- 1314
            R E    + S    N    Q+     + +E+    V+ L  +   L+ ++++  EK    
Sbjct: 3182 RDELSQQIKSLKRENDDLQQKLKSVIEEREKLEKEVNDLTQQIKSLKNEIEEQKEKSKKE 3241

Query: 1313 ----AEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEM 1146
                +E  ++ + E Q++ N+ +++QQ L  +             +    K  +    ++
Sbjct: 3242 IENFSEKLKSSNEEKQKLQNQNDDLQQKLESIKEERENLKRENDLINKKLKSQSEELQKL 3301

Query: 1145 KGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSE-TQEIDTL 969
              E+  S+S         K++N  +E +   +             ++    + T E + L
Sbjct: 3302 NKEIDYSKSQIDSLDEVNKKLNSTNEQENKQLNDQINKLTTKVNDLNNEIKKLTSEKNDL 3361

Query: 968  MDDNRK----YWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEK 801
            +D N++       +V+ F ++TQ L   ++  ++                   ++N I  
Sbjct: 3362 IDQNKRLNEDLSKKVNQFDEETQKLNEQLKRSKE-------------------EINDINN 3402

Query: 800  QLKELNIHVMQLVEHNTRLKKDVKFGFAWANSM-HDLNGQEQKL-KVDEEVPILCHQNSK 627
            Q K+L+     L + N +L  ++       NS+ ++ N Q++K   V EE   L   N++
Sbjct: 3403 QNKKLDSLNNDLKQENNKLNHEI----TKLNSLTNEFNEQKKKFDSVKEENLRLNSLNNE 3458

Query: 626  IAERLDINTDKARALDMEVQRI 561
            + +  +  + K ++L+ +++ I
Sbjct: 3459 LKQENEEISKKLKSLNEQIKEI 3480



 Score = 99.8 bits (247), Expect = 7e-18
 Identities = 147/800 (18%), Positives = 340/800 (42%), Gaps = 29/800 (3%)
 Frame = -3

Query: 3191 LQKKAGELQTKVHIREEE--SCKHLTEALENHI------YGSLLESCVVDREAHIKQLME 3036
            LQK+  E + K+  + E+  +C+   E  +  I        S L   +   +   + L+E
Sbjct: 3114 LQKEIDEREEKIKSQNEKLSNCRKEVEKTKQEIEEMKAKLNSQLTEEIQTIKGEKEDLLE 3173

Query: 3035 QMNALVKEKRELENDAQ----RGEEISQSLKDEVFQL----KEVSRLYEEEKQHTIELQE 2880
            ++ ++ KE+ EL    +      +++ Q LK  + +     KEV+ L ++ K    E++E
Sbjct: 3174 KIKSINKERDELSQQIKSLKRENDDLQQKLKSVIEEREKLEKEVNDLTQQIKSLKNEIEE 3233

Query: 2879 NFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAV 2700
                 +++ E+   K++++N   ++  N   +L  KL+  +E+R  L+ +   + +    
Sbjct: 3234 QKEKSKKEIENFSEKLKSSNEEKQKLQNQNDDLQQKLESIKEERENLKRENDLINKKLKS 3293

Query: 2699 SQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKET----VSKELAL 2532
               E ++LN+++   +  ++ L E             KQL D  N+  T    ++ E+  
Sbjct: 3294 QSEELQKLNKEIDYSKSQIDSLDEVNKKLNSTNEQENKQLNDQINKLTTKVNDLNNEIKK 3353

Query: 2531 SVSREQKLASDLKALSEKEESTKNQLLIQTEQ-NKQLELEIEKLYG-SLQMKQME--NTL 2364
              S +  L    K L+E      NQ   +T++ N+QL+   E++   + Q K+++  N  
Sbjct: 3354 LTSEKNDLIDQNKRLNEDLSKKVNQFDEETQKLNEQLKRSKEEINDINNQNKKLDSLNND 3413

Query: 2363 LKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDA 2184
            LK  N K+      L + + E   Q+    K+  ++++E  R   +     ++K+ N + 
Sbjct: 3414 LKQENNKLNHEITKLNSLTNEFNEQK----KKFDSVKEENLRLNSLN---NELKQENEEI 3466

Query: 2183 GAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIR 2004
              K+  + E +  + +      E     I+ L       +    ++ D K  L  + +I 
Sbjct: 3467 SKKLKSLNEQIKEITN------ENNQDQIDLLNKKLNENETFTRKLNDDKENLAKKLQIS 3520

Query: 2003 AQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQN 1824
             +E  +L  +V+ +   L E K++ +    + Q   + L N K ++     +   +  +N
Sbjct: 3521 NEENKKLNKKVEDLSEELEESKQREENSLIDLQNKNETLENLKTQIKKQKQQIQEINREN 3580

Query: 1823 RSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILL 1644
             +LK EL        +I + +N +E++      +++NL+     ++       ++ + L 
Sbjct: 3581 NNLKQELE---NSQIEIDDFQNQIENQ----KLKIDNLQKVTINNE-------KIIKELK 3626

Query: 1643 GQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAE 1464
             +++E+ SL  +                + L   +++ + E + + +D   +++  ++++
Sbjct: 3627 NENLELKSLTSD----------------LQLSLHSSQSEKEKIEKQNDENLRDLQKAKSD 3670

Query: 1463 AMSVLISKSLGNGRA-----NQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFE 1299
                 ++K L N        N+R+FQ  + +++ +  +    + +E  +           
Sbjct: 3671 ISD--LTKLLKNNSPQASIDNRRKFQISQTNTTDIAAVSGTFSVMEDPI----------- 3717

Query: 1298 TKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRS 1119
              S E +Q+ ++  +M++ LS              ++R+L+K+N  L+SE+  E T S  
Sbjct: 3718 --SEEIEQLKDENNKMKKDLSQ-------------KIRNLQKDNEFLKSEL--EKTKSEK 3760

Query: 1118 FKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNR 939
                 G+ +    I +++D  L++                +   +E + +   N++  +R
Sbjct: 3761 ENGLLGTKLSISEISNDNDVYLMKINNDLVKENSELKIRISLLEKENEEMKQINKEKKDR 3820

Query: 938  VSHFTKQTQSLQNSVQELQQ 879
             S   ++    +   +ELQ+
Sbjct: 3821 TSEMLREKDMRKRMEEELQK 3840



 Score = 97.4 bits (241), Expect = 3e-17
 Identities = 167/885 (18%), Positives = 360/885 (40%), Gaps = 129/885 (14%)
 Frame = -3

Query: 3149 REEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNALVKEKRELENDAQRGEEI 2970
            + E+  K LT+ +EN      L+  ++D E  +  + +Q+    ++ ++LE   +  +  
Sbjct: 715  QNEQKMKDLTDEMEN------LKRKLLDNELDV--VKDQLQKEKQKSQDLEEKIEEKDST 766

Query: 2969 SQSLKDEVFQ-LKEVSRLYEE---EKQHTI--------ELQE-----------NFNALRQ 2859
             Q LK+++ + L+E  + Y++   +KQ  I        ELQE             ++L Q
Sbjct: 767  IQILKEKINENLEESKKSYDKLMNDKQEEIALLQKQINELQELIKNNGESSKTKISSLLQ 826

Query: 2858 KNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREE 2679
            +N ++  KI+  N+LL+QKD+ I +L +++ +  + +  L+  +Q+++ +   S+++ E 
Sbjct: 827  ENTNLNTKIQQLNSLLKQKDDKINDLQNEINDLTQNKIDLEKQIQNLQTIIFDSKSQIES 886

Query: 2678 LNRQLVLLR----------DDVN-HLKEALSMAVDDRAFMEKQLQDLENQKETVSKELAL 2532
            LN ++  L+          D +N  +K+      + + F EK   D+ N+++  +++  L
Sbjct: 887  LNEKISGLQQLLKSSQETIDSLNDKIKQTQIELQESKDFAEKLQNDI-NEEKKKTEDYQL 945

Query: 2531 SVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQ----LELEIEKLYGSLQ-----MKQ 2379
             +    +L  +   L E E+S    L +   +N Q    L+ EIE+L   +      + Q
Sbjct: 946  KLDDIDRLTKERNLLKETEKS----LTLTNAENMQTIDKLKDEIEQLNDKISQLNTTIDQ 1001

Query: 2378 MENTLLKDGNEKIYDLCKL-LATKSRE-------------------VQGQQEGILKQDIN 2259
            + + + K   E   DL K  L+ K  +                   ++ + E I K++ +
Sbjct: 1002 LNDVISKKDEEIKQDLQKFELSEKVHQAAINDYQKQLEHHEEQITLLEEEIEKISKENSD 1061

Query: 2258 IEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNI------ 2097
            ++ ++   +       D+ K NS+  AK+  + E L   + ++  L EE  GN+      
Sbjct: 1062 LKAKILENEAKLDDFDDVSKQNSEYKAKIEQLEEELADYESNLQKLSEE-NGNLEIQIEE 1120

Query: 2096 -------NSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELK 1938
                   N+  N+ +     LE        L A  +   Q + +   E+ ++   +I+L+
Sbjct: 1121 IKLKTVPNTDFNELRTKNTDLEAQIRELKRLLANDDGNKQVIAQKDKEILSLNQTIIDLQ 1180

Query: 1937 RKNQTLQDE---------------------------------SQRNAKELWNAKAR---- 1869
              NQ L D+                                   +N   L N K +    
Sbjct: 1181 HNNQLLNDKIKDIEMTKTNYPERSFNNDELHQTIEDNNVSMFDMQNKLNLANLKLKQSEK 1240

Query: 1868 -LNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKE 1692
             + N+ ++ ++L+S+N  + + +++  Q     + E N +     V +S++E +  + + 
Sbjct: 1241 EIQNLKNELLSLQSENEEMNSTINMLKQSLTSKENEINELNDSVTVKNSQIEEILKKNQV 1300

Query: 1691 SKDLEGYFLRLFEILLG--QHVEVASLDIESCRFAEEKLMRIL-DELICLRNENAKLKNE 1521
              D  G   +  ++L    +H      +      ++ KL++ L D    L+ +N  L+N 
Sbjct: 1301 KFDKTGNKEQQLQVLNSSLKHSNDIIQEKGKTIDSQNKLIKNLEDTKQKLQKQNFDLQNN 1360

Query: 1520 ALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQRE----FQNKEEDSSGVDLLKNKC 1353
                 +D E+     ++ E +S+  SK+    +  Q +     Q + E+    + +KN  
Sbjct: 1361 VSNLTNDLEK-----TKRELLSLQNSKNDNIKQLEQEKELILKQKENENKISEEKIKNLT 1415

Query: 1352 TRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSL-- 1179
             ++      +S+K    +   +  Q+++N+L+ ++ +  D              +R L  
Sbjct: 1416 LQISNLQNTISQKDNEIQNNLQNLQKVSNELDFIKNSTKDHENDLTEKEDVINNLRKLFD 1475

Query: 1178 --KKENTRLRSEMKGELTPSR---SFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXX 1014
               KEN +   E +  L       S    +  F  +     +D    +Q           
Sbjct: 1476 DKMKENEKKTKEFQDSLREKDLMISQLENKTMFFDQQMKSKDDKIDSLQIQNVTFQGELK 1535

Query: 1013 KIDTR-TSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQ 882
            +I  +  +  ++ID L  +N  +   +    +        ++ELQ
Sbjct: 1536 EIQNKLINSLKQIDELQKENESFQKELQTRDQNLDDSHKQIEELQ 1580



 Score = 94.4 bits (233), Expect = 3e-16
 Identities = 137/706 (19%), Positives = 295/706 (41%), Gaps = 11/706 (1%)
 Frame = -3

Query: 3227 AQHQKILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIK 3048
            +Q ++IL+       K G  + ++ +    S KH  + ++    G  ++S    +   IK
Sbjct: 1289 SQIEEILKKNQVKFDKTGNKEQQLQVLNS-SLKHSNDIIQEK--GKTIDS----QNKLIK 1341

Query: 3047 QLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVS----RLYEEEKQHTIELQE 2880
             L +    L K+  +L+N+        +  K E+  L+       +  E+EK+  ++ +E
Sbjct: 1342 NLEDTKQKLQKQNFDLQNNVSNLTNDLEKTKRELLSLQNSKNDNIKQLEQEKELILKQKE 1401

Query: 2879 NFNAL-RQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHA 2703
            N N +  +K +++ L+I    N + QKDN I      LQ+   +   ++N  +     H 
Sbjct: 1402 NENKISEEKIKNLTLQISNLQNTISQKDNEIQNNLQNLQKVSNELDFIKNSTKD----HE 1457

Query: 2702 VSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQ--DLENQKETVSKELALS 2529
               TE+E++   L  L DD     E  +    D +  EK L    LEN+     +++   
Sbjct: 1458 NDLTEKEDVINNLRKLFDDKMKENEKKTKEFQD-SLREKDLMISQLENKTMFFDQQMKSK 1516

Query: 2528 VSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGN 2349
              +   L         + +  +N+L+   +Q  +L+ E E     LQ +      L D +
Sbjct: 1517 DDKIDSLQIQNVTFQGELKEIQNKLINSLKQIDELQKENESFQKELQTRDQN---LDDSH 1573

Query: 2348 EKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVS 2169
            ++I +L   +     E++ + E +     N+++++   +    S T+ +K+    G + S
Sbjct: 1574 KQIEELQAKIDQYEEEIKSKDENLN----NLQNKINNYEN--ESKTNNEKIKEMEGKQKS 1627

Query: 2168 GILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVL 1989
              L++     +D+ +   +       L+++ + +Q  ++   D  +E+  E++ ++++++
Sbjct: 1628 NELQI-----NDLQNNVSQTENENKQLKSELEKLQTEIKSKSDQLNEIQNESKSQSEQIV 1682

Query: 1988 RLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKA 1809
              Q E+  +Q+ L    ++   LQ E++   KE          + +++ NL+  ++ ++ 
Sbjct: 1683 TFQGELKELQNKLTSSLKQIDELQKENESFQKE----------LQTRDQNLDDSHKQIE- 1731

Query: 1808 ELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKES----KDLEGYFLRLFEILLG 1641
               LQA K  Q +EE    +   N L +++ N ++E K +    K++EG           
Sbjct: 1732 --ELQA-KIDQYEEEIKSKDENLNNLQNKINNYENESKTNNEKIKEMEG----------- 1777

Query: 1640 QHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEA 1461
                         +  E ++  + + +    NEN +LK+E                  + 
Sbjct: 1778 -----------KQKSNELQINDLQNNVSQTENENKQLKSEL----------------EKL 1810

Query: 1460 MSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREA 1281
             + + SKS         E QN+ +  S           + FQ  ++  K E  +T+  + 
Sbjct: 1811 QTEIKSKS-----DQLNEIQNESKSQSE--------QIVTFQ-DEVKSKDEKLQTQEEQI 1856

Query: 1280 QQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK 1143
            +++ NKL E++ +L +              + +LKK N  L  +++
Sbjct: 1857 KELENKLNELENSLRNKGDLQVQLNDREKELNNLKKVNENLVKQVE 1902



 Score = 91.7 bits (226), Expect = 2e-15
 Identities = 159/867 (18%), Positives = 357/867 (41%), Gaps = 88/867 (10%)
 Frame = -3

Query: 3218 QKILEDYYALQKKAGELQTKVH-----------IREEESCKHLTEALENHIYGSLLESC- 3075
            +K+  D    +KK  + Q K+            ++E E    LT A        L +   
Sbjct: 927  EKLQNDINEEKKKTEDYQLKLDDIDRLTKERNLLKETEKSLTLTNAENMQTIDKLKDEIE 986

Query: 3074 -VVDREAHIKQLMEQMNALVKEK-RELENDAQRGEEISQSLKDEVFQ--LKEVSRLYEEE 2907
             + D+ + +   ++Q+N ++ +K  E++ D Q+ E     L ++V Q  + +  +  E  
Sbjct: 987  QLNDKISQLNTTIDQLNDVISKKDEEIKQDLQKFE-----LSEKVHQAAINDYQKQLEHH 1041

Query: 2906 KQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSH---KLQENEEQRSALQ 2736
            ++    L+E    + ++N D+  KI  N   L+  D++  + S    K+++ EE+ +  +
Sbjct: 1042 EEQITLLEEEIEKISKENSDLKAKILENEAKLDDFDDVSKQNSEYKAKIEQLEEELADYE 1101

Query: 2735 NDMQSVEQ-------------MHAVSQTEREELNRQLVLLRDDVNHLKEALS-------- 2619
            +++Q + +             +  V  T+  EL  +   L   +  LK  L+        
Sbjct: 1102 SNLQKLSEENGNLEIQIEEIKLKTVPNTDFNELRTKNTDLEAQIRELKRLLANDDGNKQV 1161

Query: 2618 MAVDDRAFME--KQLQDLENQKETVS---KELALSVSREQKLASDLKALSEKEEST---- 2466
            +A  D+  +   + + DL++  + ++   K++ ++ +   + + +   L +  E      
Sbjct: 1162 IAQKDKEILSLNQTIIDLQHNNQLLNDKIKDIEMTKTNYPERSFNNDELHQTIEDNNVSM 1221

Query: 2465 ---KNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQ 2295
               +N+L +   + KQ E EI+ L   L   Q EN   ++ N  I  L + L +K  E+ 
Sbjct: 1222 FDMQNKLNLANLKLKQSEKEIQNLKNELLSLQSEN---EEMNSTINMLKQSLTSKENEIN 1278

Query: 2294 GQQEGILKQDINIEDELARTK----EVGRSATDMKKVNS----------DAGAKVSGILE 2157
               + +  ++  IE+ L + +    + G     ++ +NS          + G  +    +
Sbjct: 1279 ELNDSVTVKNSQIEEILKKNQVKFDKTGNKEQQLQVLNSSLKHSNDIIQEKGKTIDSQNK 1338

Query: 2156 MLLPMKDDVFSLKEE---VLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLR 1986
            ++  ++D    L+++   +  N+++L ND +  +  L  +Q++K++   + E   + +L+
Sbjct: 1339 LIKNLEDTKQKLQKQNFDLQNNVSNLTNDLEKTKRELLSLQNSKNDNIKQLEQEKELILK 1398

Query: 1985 LQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNI-NLESQNRSLKA 1809
             +   + I     E K KN TLQ         L N  ++ +N +  N+ NL+  +  L  
Sbjct: 1399 QKENENKIS----EEKIKNLTLQ------ISNLQNTISQKDNEIQNNLQNLQKVSNELDF 1448

Query: 1808 ELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKD-----------LEGYFLR 1662
              +        + E+ +V+ +   +   +++  + + KE +D           LE   + 
Sbjct: 1449 IKNSTKDHENDLTEKEDVINNLRKLFDDKMKENEKKTKEFQDSLREKDLMISQLENKTMF 1508

Query: 1661 LFEILLGQHVEVASLDIESCRFAEE------KLMRILDELICLRNENAKLKNEALYEYHD 1500
              + +  +  ++ SL I++  F  E      KL+  L ++  L+ EN   + E       
Sbjct: 1509 FDQQMKSKDDKIDSLQIQNVTFQGELKEIQNKLINSLKQIDELQKENESFQKEL-----Q 1563

Query: 1499 YERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLS 1320
               +N+  S  +   +         + +Q E + K +D + ++ L+NK    E + +  +
Sbjct: 1564 TRDQNLDDSHKQIEEL-------QAKIDQYEEEIKSKDEN-LNNLQNKINNYENESKTNN 1615

Query: 1319 EKAEMFETKSREAQQMANKLEE-MQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK 1143
            EK +  E K +  +   N L+  + QT ++               + LK E  +L++E+K
Sbjct: 1616 EKIKEMEGKQKSNELQINDLQNNVSQTENEN--------------KQLKSELEKLQTEIK 1661

Query: 1142 GELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMD 963
             +       ++   S  ++I +  + +   +Q             +  TS  ++ID L  
Sbjct: 1662 SKSDQLNEIQNESKSQSEQI-VTFQGELKELQ-------------NKLTSSLKQIDELQK 1707

Query: 962  DNRKYWNRVSHFTKQTQSLQNSVQELQ 882
            +N  +   +    +        ++ELQ
Sbjct: 1708 ENESFQKELQTRDQNLDDSHKQIEELQ 1734



 Score = 89.4 bits (220), Expect = 1e-14
 Identities = 129/727 (17%), Positives = 317/727 (43%), Gaps = 46/727 (6%)
 Frame = -3

Query: 3191 LQKKAGELQ-TKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNALVK 3015
            LQK + EL   K   ++ E+     E + N++   L +  + + E   K+  + +     
Sbjct: 1439 LQKVSNELDFIKNSTKDHENDLTEKEDVINNLR-KLFDDKMKENEKKTKEFQDSLREKDL 1497

Query: 3014 EKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEE----KQHTIELQENFNALRQKNED 2847
               +LEN     ++  +S  D++  L+  +  ++ E    +   I   +  + L+++NE 
Sbjct: 1498 MISQLENKTMFFDQQMKSKDDKIDSLQIQNVTFQGELKEIQNKLINSLKQIDELQKENES 1557

Query: 2846 ICLKIEANNNLLEQKDNIIVELSHKLQENEEQ-------RSALQNDMQSVEQMHAVSQTE 2688
               +++  +  L+     I EL  K+ + EE+        + LQN + + E     +  +
Sbjct: 1558 FQKELQTRDQNLDDSHKQIEELQAKIDQYEEEIKSKDENLNNLQNKINNYENESKTNNEK 1617

Query: 2687 REELNRQLVLLRDDVNHLKEALSMAVDD----RAFMEK----------QLQDLENQKETV 2550
             +E+  +       +N L+  +S   ++    ++ +EK          QL +++N+ ++ 
Sbjct: 1618 IKEMEGKQKSNELQINDLQNNVSQTENENKQLKSELEKLQTEIKSKSDQLNEIQNESKSQ 1677

Query: 2549 SKELALSVSR----EQKLASDLKALSE---------KEESTKNQLLIQT-EQNKQLELEI 2412
            S+++          + KL S LK + E         KE  T++Q L  + +Q ++L+ +I
Sbjct: 1678 SEQIVTFQGELKELQNKLTSSLKQIDELQKENESFQKELQTRDQNLDDSHKQIEELQAKI 1737

Query: 2411 EKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTK 2232
            ++    ++ K      L++      +  K    K +E++G+Q+    Q  ++++ +++T+
Sbjct: 1738 DQYEEEIKSKDENLNNLQNKINNYENESKTNNEKIKEMEGKQKSNELQINDLQNNVSQTE 1797

Query: 2231 EVGRS-ATDMKKVNSDAGAKVSGILEMLLPMK---DDVFSLKEEVLGNINSLRNDAQMVQ 2064
               +   ++++K+ ++  +K   + E+    K   + + + ++EV      L+   + ++
Sbjct: 1798 NENKQLKSELEKLQTEIKSKSDQLNEIQNESKSQSEQIVTFQDEVKSKDEKLQTQEEQIK 1857

Query: 2063 VALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELW 1884
                ++ + ++ L  + +++ Q   R + E++ ++ +   L ++ + LQ   +++ K+L 
Sbjct: 1858 ELENKLNELENSLRNKGDLQVQLNDR-EKELNNLKKVNENLVKQVEDLQVNKEQSDKKLS 1916

Query: 1883 NAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKS 1704
                 L N+   N +L+ QN  L+        +   +Q   + + + HN    E+  +K 
Sbjct: 1917 ENDEELTNLRRNNADLKKQNEKLRENKEKNESEIISLQNRLSELTNSHN---DELFTVKR 1973

Query: 1703 ELKESKDLEGYFLRLFEILLGQHVEVASL--DIESCRFAEEKLMRILDELICLRNENAKL 1530
            +L+E+  +        E+L  Q ++      D++      E L  ++     L+ EN  L
Sbjct: 1974 KLEENNSIVKQQNAKIEMLKQQLIDQNKTIEDLQKIINESENLQFLVS---TLKTENNTL 2030

Query: 1529 KNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCT 1350
            K   + + +D + K  +      ++ L +K     +++Q +   K +  S ++ +++K  
Sbjct: 2031 KK--VTQDNDLQNKKTNEDLLSQINDLQNKLKETEKSSQIQ---KSKYESQLNEIQSKLN 2085

Query: 1349 RLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKE 1170
                  Q + + +++ +    E + +  KL+E Q+  +D+                L  E
Sbjct: 2086 ------QSIKDNSDLMDKHENELKNLDEKLQESQKQKNDLEKKFEMN-------SKLLNE 2132

Query: 1169 NTRLRSE 1149
            N +LR E
Sbjct: 2133 NNKLRQE 2139



 Score = 78.2 bits (191), Expect = 2e-11
 Identities = 174/963 (18%), Positives = 377/963 (39%), Gaps = 114/963 (11%)
 Frame = -3

Query: 3050 KQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFN 2871
            ++L+++ + L+     L+N+     + + ++++    LKE+  L    ++   + +E  +
Sbjct: 202  EELVQENSQLLDRIEALQNELNNSNKSNLNIQNNADNLKEIEDLRHLNQELQQKNREQES 261

Query: 2870 ALRQKNEDIC------LKIEANNN-------LLEQKDNIIVELSHKLQENEEQRSALQND 2730
             + Q+  ++        K+  N N       +L+  ++ + EL+ KL E +++  +   D
Sbjct: 262  LISQRTSELADARNEIFKLSQNQNTESPIKSILQDTESKVAELNTKLMEADKKLKSKTKD 321

Query: 2729 MQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETV 2550
             +++EQ + V   +   +N++     D V  LK   S   D ++       D + ++  +
Sbjct: 322  FETLEQKYNVLLEQFHTINQEKKAAADQVEALK---SQIKDLQSKSANSSSDFKAKQNEI 378

Query: 2549 SKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMEN 2370
             K   ++ +++  +    +   E  +S  N      E+    + E+E L   LQ +  EN
Sbjct: 379  DKLKQINEAQKNFIEDIQRKYDELSQSNLNS---PKERTNPFQQELENLRRRLQDQDKEN 435

Query: 2369 TLLKDGNEKIYDLCKLLATK-------------------SREVQGQQEGILKQDINIEDE 2247
              L D N  + +    L ++                   S   +   + +L+ +  I D 
Sbjct: 436  KALTDQNMALNNQINFLKSQLQNSRQPLPSTQYMEEENSSNLDESDIQNMLETNQVISDY 495

Query: 2246 LARTKEVGR--------------SATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEV 2109
              + KE+                ++  MK+ NS   ++   ++  +  +K +   LK ++
Sbjct: 496  ENKIKELNETILSLRNAAPKTPDTSAKMKRENSLLKSENEELVSRVNQIKKENTQLKSDI 555

Query: 2108 LGNINSLRND----AQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIEL 1941
                N LRN     A  VQ  L  ++   ++LFA+     Q+    Q   D    IL +L
Sbjct: 556  QDLNNQLRNKKKDFAGSVQNQLNIIKLFLNKLFADFNYEIQKT--KQKISDEFLTILRKL 613

Query: 1940 KRK-----NQTLQDESQRN--AKELWNAKARLNNVMS--KNINLESQNRSLKAELHLQA- 1791
            +++     N+T   E Q N   +E    K ++N++ +  + I  E++N S +   H+   
Sbjct: 614  QQQKENETNKTKLLERQINDLKQENMKLKDKINDLQNNLQKILQENENHSKQISTHIDGL 673

Query: 1790 -----QKAFQIQEERNVVESEHNVL-------SSEVENL-KSELKESKDLEGYFLRLFEI 1650
                 ++  QI +++  +E+  N +         E  NL K   ++ KDL      L   
Sbjct: 674  SQSIKERDDQILKDKEKIENLQNKIKGKEIDFDQEKSNLIKQNEQKMKDLTDEMENLKRK 733

Query: 1649 LLGQHVEVA----------SLDIESCRFAEEKLMRIL---------------DELICLRN 1545
            LL   ++V           S D+E     ++  ++IL               D+L+  + 
Sbjct: 734  LLDNELDVVKDQLQKEKQKSQDLEEKIEEKDSTIQILKEKINENLEESKKSYDKLMNDKQ 793

Query: 1544 ENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDL- 1368
            E   L  + + E  +  + N   S+ +  S+L   +  N +  Q     K++D    DL 
Sbjct: 794  EEIALLQKQINELQELIKNNGESSKTKISSLLQENTNLNTKIQQLNSLLKQKDDKINDLQ 853

Query: 1367 -----LKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXX 1203
                 L      LE Q+Q L  +  +F++KS + + +  K+  +QQ L            
Sbjct: 854  NEINDLTQNKIDLEKQIQNL--QTIIFDSKS-QIESLNEKISGLQQLLKSSQETIDSLND 910

Query: 1202 XXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXX 1023
               + +   +E+     +++ ++       + E    ++  +  +D   L +        
Sbjct: 911  KIKQTQIELQESKDFAEKLQNDI-------NEEKKKTEDYQLKLDDIDRLTKERNLLKET 963

Query: 1022 XXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSV--------QELQQXXXX 867
                  T     Q ID L D+  +  +++S        L + +        Q+LQ+    
Sbjct: 964  EKSLTLTNAENMQTIDKLKDEIEQLNDKISQLNTTIDQLNDVISKKDEEIKQDLQKFELS 1023

Query: 866  XXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNG 687
                          ++ +  E+Q+  L   + ++ + N+ LK  +    A  +   D++ 
Sbjct: 1024 EKVHQAAINDYQKQLEHH--EEQITLLEEEIEKISKENSDLKAKILENEAKLDDFDDVSK 1081

Query: 686  Q--EQKLKVDEEVPILCHQNSKIAERLDINTDKARALDMEVQRIRLILSRIPTKPTEEAS 513
            Q  E K K+++    L    S + +  + N +    L+++++ I+L      T P  + +
Sbjct: 1082 QNSEYKAKIEQLEEELADYESNLQKLSEENGN----LEIQIEEIKL-----KTVPNTDFN 1132

Query: 512  KMR 504
            ++R
Sbjct: 1133 ELR 1135



 Score = 76.6 bits (187), Expect = 6e-11
 Identities = 119/579 (20%), Positives = 259/579 (44%), Gaps = 67/579 (11%)
 Frame = -3

Query: 3053 IKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTI--ELQE 2880
            +K+   ++N+L  E +      Q  EEIS+ LK    Q+KE++    +++   +  +L E
Sbjct: 3445 VKEENLRLNSLNNELK------QENEEISKKLKSLNEQIKEITNENNQDQIDLLNKKLNE 3498

Query: 2879 NFNALRQKNED---ICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQM 2709
            N    R+ N+D   +  K++ +N   ++ +  + +LS +L+E++++      D+Q+  + 
Sbjct: 3499 NETFTRKLNDDKENLAKKLQISNEENKKLNKKVEDLSEELEESKQREENSLIDLQNKNET 3558

Query: 2708 HAVSQTEREELNRQLVLLRDDVNHLKEALS---MAVDD-RAFMEKQLQDLEN-QKETVSK 2544
                +T+ ++  +Q+  +  + N+LK+ L    + +DD +  +E Q   ++N QK T++ 
Sbjct: 3559 LENLKTQIKKQKQQIQEINRENNNLKQELENSQIEIDDFQNQIENQKLKIDNLQKVTINN 3618

Query: 2543 ELALSVSREQKL-----ASDLKALSEKEESTKNQLLIQTEQN-KQLELEIEKLYGSLQMK 2382
            E  +   + + L      SDL+      +S K ++  Q ++N + L+     +    ++ 
Sbjct: 3619 EKIIKELKNENLELKSLTSDLQLSLHSSQSEKEKIEKQNDENLRDLQKAKSDISDLTKLL 3678

Query: 2381 QMENTLLKDGNEKIYDLCKLLATKSREVQG----QQEGILKQDINIEDE----------- 2247
            +  +      N + + + +   T    V G     ++ I ++   ++DE           
Sbjct: 3679 KNNSPQASIDNRRKFQISQTNTTDIAAVSGTFSVMEDPISEEIEQLKDENNKMKKDLSQK 3738

Query: 2246 ---LARTKEVGRSA---TDMKKVNSDAGAKVSGILEM-------LLPMKDDVFSLKEEVL 2106
               L +  E  +S    T  +K N   G K+S I E+       L+ + +D+     E+ 
Sbjct: 3739 IRNLQKDNEFLKSELEKTKSEKENGLLGTKLS-ISEISNDNDVYLMKINNDLVKENSELK 3797

Query: 2105 GNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRA---QEVLRLQAEVDAIQHILIELKR 1935
              I+ L  + + ++   ++ +D  SE+  E ++R    +E+ +L+       +++  +KR
Sbjct: 3798 IRISLLEKENEEMKQINKEKKDRTSEMLREKDMRKRMEEELQKLRRSDKEKNNLIQRIKR 3857

Query: 1934 KNQTLQDESQRNAKEL---------WNA---------KARLNNVMSK-NINLESQNRSLK 1812
            K +T Q+E ++  +E+          NA         K  LN++  + N ++  +N  LK
Sbjct: 3858 KEETAQEEVRKVKEEMIILKKVCDEKNAAFEKLSEEHKMILNSLKGRNNESILEENERLK 3917

Query: 1811 AELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRL-FEILLGQH 1635
             EL     ++        + E     L + +E+L++   E++ L     +   E    + 
Sbjct: 3918 EELENARNESVSNDSYLKINEEVEKNLQTALESLQNAKDENERLTKKLQKTERENKSLKQ 3977

Query: 1634 VEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEA 1518
            +  +S D++S  F EE++  +  E+  LR E     N A
Sbjct: 3978 IIKSSEDLKSSEF-EEEIDNLKTEVKKLRKEKKSFTNVA 4015


>ref|XP_005159743.1| PREDICTED: titin isoform X6 [Danio rerio]
          Length = 15134

 Score =  123 bits (309), Expect = 5e-25
 Identities = 190/963 (19%), Positives = 427/963 (44%), Gaps = 76/963 (7%)
 Frame = -3

Query: 3224  QHQKILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQ 3045
             + QKI ++   L +   ELQ      E E  ++L E ++           + + EAH+++
Sbjct: 10243 ERQKIADEQDLLIQNKSELQN-----ENERIRNLNEIIKKE------RETLKEMEAHLEK 10291

Query: 3044  LMEQMNALVKEKRELENDAQR-GEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNA 2868
               E++ ++ +E R L+ D ++   ++++  KD + Q   + +  EE      +LQ+  + 
Sbjct: 10292 KKEEIKSVSEETRRLKEDLEKMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQQRIDE 10351

Query: 2867  L-----RQKNEDICLK--IEANNNLLEQKDNIIVELSHKLQENE---EQRSALQNDMQSV 2718
                   +QK +D+  +  ++ +   LE+    ++E+  K +  E   E+    + + +  
Sbjct: 10352 FDAQVSKQKEQDLPKEKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEEEEE 10411

Query: 2717  EQMHAVSQTEREELNR---QLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVS 2547
             E++  + +TER+EL +   +L  +R +++H ++ L+   D    +E++ +DLE  K  + 
Sbjct: 10412 EEIRVIVETERKELYQIKSELERVRSEIDHEQKKLN---DYMKMIEQEKEDLEKMKSEIM 10468

Query: 2546  KELALSVSREQKLASDLKALS------EKEESTKNQLLIQTE-QNKQLELEIEKLYGSLQ 2388
             K+         +L + ++  +      EK +    +L+++ E Q K ++L+ E+L    Q
Sbjct: 10469 KQRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQ 10528

Query: 2387  MKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTK----EVGR 2220
                 E  LL     K+ +  + +     E++ ++E + + +I+++ E    +    E  R
Sbjct: 10529 KIADEQNLLVQNKAKLQNENERIKKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQR 10588

Query: 2219  SATDMKKVNSDAGAKVSGILEMLLPMK---DDVFSLKEEVLGNINSLRN-----DAQM-- 2070
                D++K+++D       I E  L +K   D +   +EE+   +  L+      DAQ+  
Sbjct: 10589 RKEDLEKMSTD-------INEQKLHLKNQRDLLEQEREEINHEMTQLQQRIDEFDAQVSK 10641

Query: 2069  ---------VQVALEQMQDTKSELF-AEAEIRAQEVLRLQAEVDAIQ-HILIELKRKN-Q 1926
                      ++   + +++TK+ +   + +   QE+++ + E D  +  +++E++R+   
Sbjct: 10642 QREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVIVEMEREELN 10701

Query: 1925  TLQDESQRNAKELWNAKARLNNVMSKNINLESQN-RSLKAELHLQAQKAFQIQEERNVVE 1749
              ++ E +R   E+ + + +LN+   K I  E ++   +K+E+  Q Q   Q++EER+  E
Sbjct: 10702 QIKSELKRVRSEIDHEQKKLND-DKKIIEQEKEDLEKMKSEIMTQRQ---QMEEERS--E 10755

Query: 1748  SEHNVLSSEVENLKSELKESKDL-EGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRI 1572
              ++ +  +++E  + +++ SK++ +   +++ E      ++   LDIE  + A+E+ + +
Sbjct: 10756 LDNKIKQTDLE--RHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQGL-V 10812

Query: 1571  LDELICLRNENAKLK---------NEALYEYHDYERKNVSGSRA-------------EAM 1458
             +     L+NEN ++K          E L E   + RK     R+             E M
Sbjct: 10813 VQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKM 10872

Query: 1457  SVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQ----KLSEKAEMFETKS 1290
             S  ++K       NQR+   +E +      + +K T+L+ ++     ++S++ E   TK 
Sbjct: 10873 STDVNKQ-NQDLMNQRDLLKQEREE-----INHKWTQLQQRIDEFDAQVSKQKEEDLTKQ 10926

Query: 1289  REAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEM-KGELTPSRSFK 1113
             ++ ++    LEE +  + +M            + +  ++E  R + EM K EL   +S  
Sbjct: 10927 KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKE-EEEVMRAKVEMKKEELDQIKSQL 10985

Query: 1112  HREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVS 933
              R  S I        DD  +I+           +I  +  + +E  + +D      N++ 
Sbjct: 10986 ERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELD------NKIK 11039

Query: 932   HFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHN 753
                 +   ++NS + +Q+                    M  +E+Q K++ +   +L    
Sbjct: 11040 QTDLERHDIENSKEIVQKL-------------------MVEVEEQRKDIRLQKEELDIER 11080

Query: 752   TRLKKDVKFGFAWANSMHDLNGQEQKLKVDEEVPILCHQNSKIAERLDINTDKARALDME 573
              ++  +   G    N     N  E+  ++DEE+        ++   L    ++ R++  E
Sbjct: 11081 QKIADEQ--GLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEE 11138

Query: 572   VQR 564
              QR
Sbjct: 11139 TQR 11141



 Score =  120 bits (300), Expect = 5e-24
 Identities = 202/991 (20%), Positives = 424/991 (42%), Gaps = 68/991 (6%)
 Frame = -3

Query: 3224  QHQKILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQ 3045
             + Q I+++ Y L +   ELQ K      E  +++ EA++N          + + EAH+++
Sbjct: 9674  ERQNIVDEKYLLAQCETELQNK-----SEQIRNMEEAVKNE------RETLKETEAHLQR 9722

Query: 3044  LMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHT----IELQEN 2877
               +++ ++++E    + D    E+IS  +  +  +LK      E+E++       + Q+ 
Sbjct: 9723  DKKEIKSIIEETSRQKEDL---EKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQR 9779

Query: 2876  FNAL-----RQKNEDI-----------CLKIEANNNLLEQKDNIIVE---LSHKLQENEE 2754
              +       +QK ED+           CL+ E N  ++E K    +E   ++ K++E + 
Sbjct: 9780  IDEFDAQVRKQKEEDLTNQKKMEEERKCLE-EVNGKIIEMKTKAELEHHEINQKIEELQT 9838

Query: 2753  QRSALQNDMQSVEQMHAVSQTEREELNR---QLVLLRDDVNH----LKEALSMAVDDRAF 2595
              +  +  + +  E M    + ERE+L++   +LV  + +V+H    L + + M   ++  
Sbjct: 9839  LQEQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKED 9898

Query: 2594  MEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELE 2415
             +EK   ++  QK+ + KE +   ++ Q+   +   + + +E  +  +    EQ  +++L+
Sbjct: 9899  LEKMKSEIMTQKQEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRHEIQLQ 9958

Query: 2414  IEKLYGSLQMKQMENTL-------LKDGNEKIYDLCKLLATKSREVQGQQEGILKQD--- 2265
              E+L    Q    E  L       L++ NE+I ++ +++  K RE   + E  L+++   
Sbjct: 9959  KEELDIERQKIADEQDLLIQNKSELQNENERIRNINEVI-KKERETLKEMEAHLEKEKEE 10017

Query: 2264  -INIEDELARTKE-VGRSATDMKKVNSDAGAKVSGILEM----------LLPMKDDVFSL 2121
               +I +E  R KE + + +TD+K+ N D   K   +LE            L  + D F  
Sbjct: 10018 MKSITEETRRQKEDLEKMSTDIKEQNQDL-MKQRDLLEQEKEDINHEWTQLQQRIDEFDA 10076

Query: 2120  -----KEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQH 1956
                  KEE L     ++ + +    +LE+ +    E+  +AE+   +  + + E +    
Sbjct: 10077 QVSKQKEEDLTKQKEMKEERK----SLEETKARIIEMKTKAELEDIKKEKEKEEEEEEMR 10132

Query: 1955  ILIELKRKN-QTLQDESQRNAKELWNAKARLNNVMSKNINLESQN-RSLKAELHLQAQKA 1782
             + +E+  K    ++ E +R   E+ + + +LN+   K I  E QN   +K+E+  Q Q  
Sbjct: 10133 VKVEMDGKELDRIKSELKRERSEIDHEQKKLND-DKKIIEQEKQNLEKMKSEIMKQRQ-- 10189

Query: 1781  FQIQEERNVVESEHNVLSSEVENLKSELKESKDL-EGYFLRLFEILLGQHVEVASLDIES 1605
              Q++EER+  E E+ +  + +E  K +++ SK++ +   + + E       +   LDIE 
Sbjct: 10190 -QMEEERS--ELENKIKQTYIE--KCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIER 10244

Query: 1604  CRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNG 1425
              + A+E+ + I ++   L+NEN +++N  L E    ER+ +     + M   + K     
Sbjct: 10245 QKIADEQDLLIQNKSE-LQNENERIRN--LNEIIKKERETL-----KEMEAHLEKKKEEI 10296

Query: 1424  RANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREA----QQMANKLE 1257
             ++   E +  +ED      L+   T +  Q + L  + ++ E +  E     +Q+  +++
Sbjct: 10297 KSVSEETRRLKED------LEKMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQQRID 10350

Query: 1256  EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINI 1077
             E    +S                R   +E      EMK +  P    K +E    KE   
Sbjct: 10351 EFDAQVSKQKEQDLPKEKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKE----KENEE 10406

Query: 1076  GDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNS 897
              +E++  +              ++T   E  +I + ++  R   + + H  K+       
Sbjct: 10407 EEEEEEEI-----------RVIVETERKELYQIKSELERVR---SEIDHEQKKLNDYMKM 10452

Query: 896   VQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQ--LVEHNTRLKKDV--K 729
             +++ ++                       +E++  EL+  + Q  L +H+    K++  K
Sbjct: 10453 IEQEKEDLEKMKSEIMK--------QRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEK 10504

Query: 728   FGFAWANSMHDLNGQEQKLKVDEEVPILCHQNSKIAERLDINTDKARALDMEVQRIRLIL 549
                       D+  Q+++L ++ +         KIA+  ++       L  E +RI+   
Sbjct: 10505 LMVEVEEQRKDIQLQKEELDIERQ---------KIADEQNLLVQNKAKLQNENERIK--- 10552

Query: 548   SRIPTKPTEEASKMRVPLRAFLVGSKKDQSK 456
                  K  EE  K R  LR   +  KK++ +
Sbjct: 10553 -----KVDEEIKKERETLREMEIHLKKEKEE 10578



 Score =  115 bits (289), Expect = 9e-23
 Identities = 173/956 (18%), Positives = 419/956 (43%), Gaps = 50/956 (5%)
 Frame = -3

Query: 3173 ELQTKVHIREEESCKHLTEALENHIYG--SLLESCVVDREAHIKQLMEQMNALVKEKREL 3000
            +LQ ++H ++ E     TE  +++I    + +   V D ++ I  L     +L  ++   
Sbjct: 5932 QLQAEIHKQQSE-----TEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAF 5986

Query: 2999 ENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANN 2820
            EN+ +  +++   L+ E  +++++    + E+Q   E+  +F            +++ N 
Sbjct: 5987 ENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERK---QLDKNK 6043

Query: 2819 NLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVN 2640
             ++E++     E+  K  + ++ R +L  D++ ++    V + E+ +L +  + L  + +
Sbjct: 6044 VMIEEQKQ---EMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLEREAD 6100

Query: 2639 HLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKN 2460
             + +      ++R  +EK    L+ ++E +++E    + R+ ++   +K  +E       
Sbjct: 6101 EISKIKEETQNERQNLEKMANALKEEREYLAEE----IKRKNQVLDKIKVANE------- 6149

Query: 2459 QLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEG 2280
              L   ++ K++ LE  +   S Q++ +EN   K+ ++   D  K L T   EVQ QQ  
Sbjct: 6150 STLADLQKEKRI-LEEMRENISKQIEDIENE--KEKSKLREDELKKLQT---EVQKQQSE 6203

Query: 2279 ILKQDINIEDE-LARTKEVGRSATDMKKVNSDAGAKVSGIL---EMLLP----MKDDVFS 2124
            I  +  NIE E  A  +E     T++KK + D   ++  IL   E+L      +K DV  
Sbjct: 6204 IDMEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVED 6263

Query: 2123 LKEEVLG---NINSLRNDAQM--------------VQVALEQMQDTKSELFAEAEIRAQE 1995
            L+++++    +  SL+ D +               +Q+  ++++  K E   E +   ++
Sbjct: 6264 LQQKLMSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEK 6323

Query: 1994 VLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSL 1815
              ++Q E + I  ++ E+K+K   + +      KE    ++  +++         QN+++
Sbjct: 6324 TAQIQKEREEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNI 6383

Query: 1814 KAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQH 1635
            +  L        +IQ++RN +E     +S +   L+ E KE +            L  + 
Sbjct: 6384 EIAL-------AEIQQKRNALEKMSKEISRDRMKLEDEKKEIQ------------LAREE 6424

Query: 1634 VEVASLDIESCRFAEEKLMR-ILDELICLRNE-NAKLKNEALYEYHDYERKNVSGSRAEA 1461
            +E    D++  + A++ L+  I DE +  ++E    L+   + +     +  +S S  + 
Sbjct: 6425 LERMHGDMQRQQEAKDHLLSGITDESLLKKSEAEIVLQPSQVDKAKPARKTEISDSDKQP 6484

Query: 1460 MSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREA 1281
            + V     +    A +++F++++ D   V  +  +  +++ + + + ++ +  +    E 
Sbjct: 6485 VFVQQMPEMDLKDALKKDFESEKLDLPKVKDVLPQDQQMKLEQKLIEDEMDKLKQMRAEL 6544

Query: 1280 QQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK----GELTPSRSFK 1113
            Q+ A+++E+ +Q   DM            R++  ++ N RL  E+      +   + +F+
Sbjct: 6545 QKEADQIEKKKQ---DMQNERQKLDDMAARLQEERRTNERLNEEINIQKVNQQKQATAFQ 6601

Query: 1112 HREGSFIK---EINIGDEDDTPLIQXXXXXXXXXXXKIDT----RTSETQEIDTLMDDNR 954
              +  F +   EI+  +++     +           + +T    R + +++++T+ ++N+
Sbjct: 6602 MEKTDFERIKTEIDQANKELADQQEKNKKTITEMQKERETLEEMRANISKQVETITNENK 6661

Query: 953  KYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGID---------MNSIEK 801
               +R S   K  + +    QE+ +              +   ID         M+  + 
Sbjct: 6662 SLSSRESELAKLQEDILQQQQEMDELKNTIMMEMCQLDQRQSDIDLLQKEVDDLMDFTKT 6721

Query: 800  QLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEEVPILCHQNSKIA 621
            ++  +    ++++     +K D+      +  M     ++ +LK++EE  ++  +   + 
Sbjct: 6722 EMANVERERLEVLAQTRNIKSDMV-----SLKMEKEACEQLRLKLNEEKDLIEKERELLT 6776

Query: 620  ERLDINTDKARALDMEVQRIRLILSRIPTK-PTEEASKMRVPLRAFLVGSKKDQSK 456
            + LD +TDK + +DM+ +   L + +   K   +E  KM++ L+   +G K+   K
Sbjct: 6777 KNLD-HTDKDK-MDMKRELENLKVEKETIKNEKKELEKMKISLQRKAIGFKEFSEK 6830



 Score =  112 bits (280), Expect = 1e-21
 Identities = 143/727 (19%), Positives = 310/727 (42%), Gaps = 20/727 (2%)
 Frame = -3

Query: 3224  QHQKILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQ 3045
             + QKI ++   L +   ELQ      E E  K++ E ++           + + EA++++
Sbjct: 11357 ERQKIADEQDLLIQNKSELQN-----ENERIKNINEVIKKE------RETLKEMEAYLEK 11405

Query: 3044  LMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTI----ELQEN 2877
               E+M ++ +E R  + D    E++S  + ++   L+    L E+E++       +LQ+ 
Sbjct: 11406 EKEEMKSITEETRRQKEDL---EKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQR 11462

Query: 2876  FNAL-----RQKNEDICLKIEANNNL--LEQKDNIIVELSHKLQENE-EQRSALQNDMQS 2721
              +       +QK ED+  + E   +   LE+    I+E+  K +  E ++    + + Q 
Sbjct: 11463 IDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQE 11522

Query: 2720  VEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKE 2541
             +     + + E E++  QL  +R +++H ++ L+   DD+  +E++ +DLE  K  + K+
Sbjct: 11523 MRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLN---DDKKMIEQEKEDLEKMKSEIMKQ 11579

Query: 2540  LALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLL 2361
                      +L   +K    ++   +N      E  ++L +E+EK    +Q ++ E   L
Sbjct: 11580 RQQMEEERSELDKKIKQTDLEKHDIENS----KEIVEKLMVEVEKQKHEIQFQKEE---L 11632

Query: 2360  KDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAG 2181
                 +KI D   LL     E Q + E I + D  I+ E    KE+  +    K+      
Sbjct: 11633 DIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNLQKEKEEIESVI 11692

Query: 2180  AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRA 2001
              +     E L  M  D+   K++++   + L+ + + +   L Q+Q    E    + I  
Sbjct: 11693 EETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFETTSNILV 11752

Query: 2000  QEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNR 1821
                +  + E+D     L +  ++ +++ +E+ R   EL   +          ++   QN+
Sbjct: 11753 TTKMEEKTEMD---EKLQQAIKEYESIIEETNRKRTELEEIE----------VDQSQQNK 11799

Query: 1820  SLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEI--- 1650
             +++    L       +++ER   E E   L  + ++L+ ++ E  D E    R  +    
Sbjct: 11800 NVETMKDL-------LEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSLDEEKK 11852

Query: 1649  LLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSR 1470
             LL Q         +     +E +M+  +EL  L+ E    KNE      + E K +   +
Sbjct: 11853 LLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKEIQNQKNEMEEIKCELETKRIEIIK 11912

Query: 1469  AEAMSVLISKSLGNGRANQREFQ----NKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMF 1302
              +     + +SL      ++  +    + E+    ++ ++ K      ++ +L  K  M 
Sbjct: 11913 EQKR---LEESLNTVNEERQYLEIVRVDYEKHQQQIEEMRVKTKMERDELDQLMAKMLMD 11969

Query: 1301  ETKSREAQQMANKLE-EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPS 1125
               ++  ++ M   L+ EM+QT  ++            ++++ KK+    ++E+K E +  
Sbjct: 11970 RKENERSKDMIGLLKKEMEQTKFNLDAQEEELKLEKQKIQNEKKDLEMFKAEIKREASEV 12029

Query: 1124  RSFKHRE 1104
             ++ K ++
Sbjct: 12030 KTLKEQQ 12036



 Score =  108 bits (269), Expect = 2e-20
 Identities = 182/872 (20%), Positives = 371/872 (42%), Gaps = 72/872 (8%)
 Frame = -3

Query: 3068 DREAHIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTI- 2892
            D E  IK +    + L KEK +LE             + E++++KE     E++K++T+ 
Sbjct: 5638 DIEKKIKSIQSDKDMLEKEKHDLEKT-----------RSELYKVKED---LEKQKENTLA 5683

Query: 2891 ELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQ 2712
            ++Q+    L + NE+I  ++    +  EQ       ++ K  E ++ ++ +QN  Q +E+
Sbjct: 5684 QIQKEREDLEKMNENITREMHEIKHQEEQ-------MNQKQDELDQLKTEIQNLQQELEK 5736

Query: 2711 MHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELAL 2532
               +    R +L+R+   L     ++ + +    ++R  ++K  +++E QK+ + KE   
Sbjct: 5737 EKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDN 5796

Query: 2531 SVSREQKLASDLKALS------EKEESTKNQLLIQTE-------------QNKQ--LELE 2415
                 + L  DLK +       E+E++   Q+ I+ E             QNK+  LE  
Sbjct: 5797 MDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKM 5856

Query: 2414 IEKL--------YGSLQMKQMENTL--LKDGNEKIYDLCKLLATKSREVQGQQEGILKQD 2265
             E+L        + +   K+ +N+L  +K  NE    +  L   KS  ++  +E I KQ 
Sbjct: 5857 AEELKKERKDVAHLAEDTKREKNSLDEMKVANES--SMADLQKEKS-NLEEMKENISKQT 5913

Query: 2264 INIEDE----LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNI 2097
             +IE E      R  E+ +   ++ K  S+   + S I      +  DV  L+ +++   
Sbjct: 5914 EDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKII--- 5970

Query: 2096 NSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQ 1917
             SL  DA+ +++  E  ++ K EL        Q    L+ E D I+ I +E + + Q ++
Sbjct: 5971 -SLDRDAESLKLDREAFENEKEEL-------KQMKTELEREADEIEKIKLETQHERQRVE 6022

Query: 1916 DESQRNAKELWNAKARL--NNVM---------SKNINLESQNRSLKAELHLQAQKAFQIQ 1770
            + +    + + N + +L  N VM          K  +++   +SL  +L +   +   ++
Sbjct: 6023 EMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLE 6082

Query: 1769 EERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAE 1590
            EE+N +E     L  E + + S++KE    E   L      L +  E  + +I       
Sbjct: 6083 EEKNKLEQMKIGLEREADEI-SKIKEETQNERQNLEKMANALKEEREYLAEEI------- 6134

Query: 1589 EKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQR 1410
            ++  ++LD++        K+ NE+       E++ +     E M   ISK +        
Sbjct: 6135 KRKNQVLDKI--------KVANESTLADLQKEKRIL-----EEMRENISKQI-------E 6174

Query: 1409 EFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETK--------SREAQQMANKLEE 1254
            + +N++E S    L +++  +L+ +VQK   + +M +T          RE Q M  +L++
Sbjct: 6175 DIENEKEKSK---LREDELKKLQTEVQKQQSEIDMEKTNIESERAAMIREKQNMMTELKK 6231

Query: 1253 MQQTLSDMXXXXXXXXXXXIRVRS-LKKENTRLRSEMKGELTPSRSFKHREGSFIKEINI 1077
              + +                 R+ LKK+   L+ ++      S S K  + +F  E   
Sbjct: 6232 KSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIERDSESLKLDKEAFENEKEA 6291

Query: 1076 GDEDDTPL------IQXXXXXXXXXXXKIDTRTS----ETQEIDTLMDDNRKYWNRV--- 936
              +  T L      I+           +++ +T+    E +EI+TL+++ +K  + +   
Sbjct: 6292 MKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIKKKRDIIDES 6351

Query: 935  -SHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDM--NSIEKQLKELNIHVMQL 765
             +   K+ +++++   +L++                  I    N++EK  KE++   M+L
Sbjct: 6352 YTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQQKRNALEKMSKEISRDRMKL 6411

Query: 764  VEHNTRLKKDVKFGFAWANSMHDLNGQEQKLK 669
             +     KK+++        MH    ++Q+ K
Sbjct: 6412 EDE----KKEIQLAREELERMHGDMQRQQEAK 6439



 Score =  106 bits (265), Expect = 6e-20
 Identities = 162/834 (19%), Positives = 352/834 (42%), Gaps = 52/834 (6%)
 Frame = -3

Query: 3227  AQHQKILEDYYALQKKAGELQTKVHIRE-----------EESCKHLTE-----ALENHIY 3096
             ++ QK+L    ALQ +  EL+ +V + E           EE  K L E       E + Y
Sbjct: 8713  SERQKLLLLQGALQSQESELENRVFMEEQKHLKQAKAETEECRKQLAEMSETVTTEQNEY 8772

Query: 3095  GSLLESCVVDREAHIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLY 2916
               L+E    ++E    QL    N + +EK++L+N     E   +SL+ E   +++     
Sbjct: 8773  RKLIEELQREKE----QLEISKNQIEQEKKDLQNMKSNLERQLESLRHEKANVEDEKNAL 8828

Query: 2915  EEEKQHTIELQENFNALRQKNEDI---CLKIEANNNLLEQKDNIIVELSHKLQENEEQRS 2745
             E+ +  + E+Q   NA+R++ ED+    ++IE     +E++      L    +E ++  S
Sbjct: 8829  EKMRSESKEIQ---NAIRKEREDLENCWVEIEGEKKRMEEETR---RLEMHREEIKKVDS 8882

Query: 2744  ALQNDMQSVEQMHAVSQTEREELNRQLVLL---RDDVNHLKEALSMAVDDRAFMEKQLQD 2574
              LQ   +++E        + EEL +  V +   ++++    + L  A  D    + ++Q 
Sbjct: 8883  ELQKSRENIESREEKINNKMEELLQMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQR 8942

Query: 2573  LENQKETVSKELALSVSREQKLASD--LKALSEKEESTKNQLLIQTEQNKQLELEIEKLY 2400
              E++ E +         RE K+  D   K LSE+ E     L ++    K+ + EIE   
Sbjct: 8943  QEDKFEDIIDIKIQEKEREIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTK 9002

Query: 2399  GSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGR 2220
             G L+ ++ E   LK   +++ D    L  + +E + ++  ++     +ED L +  E+ +
Sbjct: 9003  GLLEKEKQE---LKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLED-LRKENEIVK 9058

Query: 2219  SATDMKKVN-SDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQ 2043
                 ++K N  +   K+     +    +++    KE +           QM++++  +M 
Sbjct: 9059  EKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKEKESLEQQRFETEQQKQMLEISTTKMM 9118

Query: 2042  DTKSE---LFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKA 1872
             + K+E   L  E +    E+ ++  + +  +H   E+++    L  + Q   ++    + 
Sbjct: 9119  EEKNEMADLSRELQKAKDELEKIAYKTNKERH---EVEQMQAELHSQIQAIEQQGQIMQD 9175

Query: 1871  RLNNVMSKNINLESQNRSLK---AELHLQAQKAFQIQEERNVVESEHNVLSSEVE----- 1716
             + N++  K ++++ +   +K    E  ++ +    + EE N  + +  V+ +++E     
Sbjct: 9176  KQNHLEEKELSIQRKEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQK 9235

Query: 1715  -----NLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICL 1551
                   L  +++   + E Y L+++       VEV   ++E     +E+L ++  EL   
Sbjct: 9236  NNKDFELLEKIRSELENEKYDLQIWTEQQKHLVEVQLQELEK---EKERLEKMEIELQSK 9292

Query: 1550  RNENAKLK-------NEALYEYHDYERKNVSGSRA-EAMSVLISKSLGNGRANQREFQNK 1395
             R +  K K        E   E    ++K    +RA E +  + ++        Q E +  
Sbjct: 9293  REQTEKEKADLNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKL 9352

Query: 1394  EEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSR-EAQQMANKLEEMQQTLSDMXXXX 1218
             EE+   V +      ++  ++++  EK E+ E   +   +Q  N  EE ++   D+    
Sbjct: 9353  EEEKLLVQIEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQI 9412

Query: 1217  XXXXXXXIRVRSLKKENTRLRSEMKGEL--TPSRSFKHREGSFIKEINIGDEDDTPLIQX 1044
                      +   +K+  + + E++ +      R   HRE   + + ++ DE+   L Q 
Sbjct: 9413  QNNENAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSL-DEEKKLLEQ- 9470

Query: 1043  XXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQ 882
                       K +    +  +++   +D  K WN++     + Q+   +++E++
Sbjct: 9471  ----------KANEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIK 9514



 Score =  106 bits (264), Expect = 8e-20
 Identities = 172/944 (18%), Positives = 381/944 (40%), Gaps = 50/944 (5%)
 Frame = -3

Query: 3224 QHQKILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQ 3045
            +HQ+  E     Q +  +L+T++   ++E  K     +++     L +S +  ++ ++  
Sbjct: 4834 KHQE--EQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMND 4891

Query: 3044 LMEQMN-----------ALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEK-- 2904
            +ME M             + ++K+E+E +    ++  +SL ++  ++K   +++EEEK  
Sbjct: 4892 IMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNK 4951

Query: 2903 --QHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQND 2730
              Q  IEL+   + + +  E+   K +    + E+       L+H  ++ + ++  L   
Sbjct: 4952 LEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEM 5011

Query: 2729 MQSVEQMHAVSQTER---EELNRQLVLLRDDVNHLKEALSMAVDD----RAFMEKQLQDL 2571
              + E   A  Q E+   EE+   +  L++ +++ KE   +  D+    +  ++KQ   +
Sbjct: 5012 KVANESSMADLQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKI 5071

Query: 2570 ENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTE----QNKQLELEIEKL 2403
            + +K  +  E A  +  +Q + ++LK  SE  E    ++L + E      K L  ++E L
Sbjct: 5072 DMEKTNIESERAAMIREKQNMMTELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVENL 5131

Query: 2402 YGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVG 2223
               L   + ++  LK   E   +  + +     ++Q Q + I K  +  + +  R +E+ 
Sbjct: 5132 QQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEM- 5190

Query: 2222 RSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLK-EEVLGNINSLRNDAQMVQVALEQM 2046
              A  ++K       K++ ++E     KD V + K  ++   I S+++D  M++     +
Sbjct: 5191 --AAQIQKERD----KINNLIEE-TNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNL 5243

Query: 2045 QDTKSELF--------------AEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDES 1908
            + T+SEL+              AE +   ++V ++   +    H +   + +    QDE 
Sbjct: 5244 EKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDEL 5303

Query: 1907 QRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLS 1728
             +   E+ N +  L       +   SQ    ++EL  Q      I E    +++E   L 
Sbjct: 5304 DQLKTEIQNLQQELEKEKEIIMKDRSQFDLRQSELDKQQTNMNDIME---TMKNERKQLD 5360

Query: 1727 SEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLR 1548
             + E ++ E K+  + E +        L + +++  L  +     + KL ++  EL    
Sbjct: 5361 KDKEEME-EQKQEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREA 5419

Query: 1547 NENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDL 1368
            +E  K+K E   E    E+      + +     ++           E   KE++      
Sbjct: 5420 DEIRKIKEETQNERQSLEKMTEELKKEKESFTHLA-----------EDTKKEQEILDKVK 5468

Query: 1367 LKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRV 1188
            + N+    + Q +K S   EM E  S++ + + NK E ++    ++            + 
Sbjct: 5469 VANESLMADLQKEK-SNLEEMRENISKQTEDVENKKENLRLREDEL---WQLQAEIYKQQ 5524

Query: 1187 RSLKKENTRLRSEMKGELTPSRSFKH------REGSFIKEINIGDEDDTPLIQXXXXXXX 1026
            R ++KE   + SE    +      +H      R+   +K      E++  +++       
Sbjct: 5525 REIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELE 5584

Query: 1025 XXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXX 846
                +I+    ETQ       D ++     +   K    + N ++E  +           
Sbjct: 5585 READEIEKIKLETQH------DRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRD 5638

Query: 845  XXXKWGGI--DMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKL 672
               K   I  D + +EK+  +L     +L +    L+K  +      N++  +  + + L
Sbjct: 5639 IEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKE------NTLAQIQKEREDL 5692

Query: 671  -KVDEEVPILCHQNSKIAERLDINTDKARALDMEVQRIRLILSR 543
             K++E +    H+     E+++   D+   L  E+Q ++  L +
Sbjct: 5693 EKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEK 5736



 Score =  106 bits (264), Expect = 8e-20
 Identities = 174/831 (20%), Positives = 342/831 (41%), Gaps = 108/831 (12%)
 Frame = -3

Query: 3215  KILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREA----HIK 3048
             K+LE+    Q+K    +  + + +E+ C++  E  E        + C ++ +     + K
Sbjct: 9368  KVLEEIKRQQEKLEISEADLKVMKEQ-CENAREETER-------KKCDIEEQIQNNENAK 9419

Query: 3047  QLMEQMNALV-KEKRELENDA----------QRGEEISQSLKDEVFQL-----KEVSRL- 2919
              L+EQ    + K+K+EL+  A          +   E+S+   DE  +L      E+ R  
Sbjct: 9420  HLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQR 9479

Query: 2918  --YEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQE-----N 2760
                E+EK+  ++     + L+ + ++    +E     L+ K N I +   +L+E     N
Sbjct: 9480  DDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAIN 9539

Query: 2759  EEQ------RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRA 2598
             EE+      R+  +   Q +E+M   ++ ER+EL++    L  D   +        +DR 
Sbjct: 9540  EEKGDLEIMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRN 9599

Query: 2597  FMEKQLQDLENQKETVSKELALSVSREQKLASDLK-ALSEKEESTKNQLLIQTEQNKQLE 2421
              +EK+  DLE  K  +  +         +L   +K A +EK++  KN+ +++     +L 
Sbjct: 9600  MIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVE-----RLM 9654

Query: 2420  LEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELA 2241
              E+E+     ++K+ E  L +   + I D   LLA    E+Q + E I   +  +++E  
Sbjct: 9655  AEVEEQRNDFKLKKEELALER---QNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERE 9711

Query: 2240  RTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSL-------KEEVLGNINSLRN 2082
               KE        KK       ++  I+E     K+D+  +       K+E+    ++L  
Sbjct: 9712  TLKETEAHLQRDKK-------EIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQ 9764

Query: 2081  DAQMVQVALEQMQDTKSELFAEAEIRAQEVL----RLQAEVDAIQHI---LIELKRKNQT 1923
             + + +     Q Q    E  A+   + +E L    +++ E   ++ +   +IE+K K + 
Sbjct: 9765  EREEINHKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAEL 9824

Query: 1922  LQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESE 1743
                E  +  +EL   +     +M +    E+    LK E     Q   ++  E+  V+ E
Sbjct: 9825  EHHEINQKIEELQTLQ---EQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREKTEVDHE 9881

Query: 1742  HNVLSSEV----------ENLKSELKESK-----------------DLEGYFLR------ 1662
                L+ ++          E +KSE+   K                 DLE + +       
Sbjct: 9882  QKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERSELDNKIQQTDLEKHDIEKSKEIV 9941

Query: 1661  ---LFEILLGQH---VEVASLDIESCRFAEEKLMRILDELICLRNENAKLKN-------- 1524
                +FE+   +H   ++   LDIE  + A+E+ + I ++   L+NEN +++N        
Sbjct: 9942  EKLMFEVEEQRHEIQLQKEELDIERQKIADEQDLLIQNKSE-LQNENERIRNINEVIKKE 10000

Query: 1523  -------EALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLL 1365
                    EA  E    E K+++         L   S      NQ   + ++      + +
Sbjct: 10001 RETLKEMEAHLEKEKEEMKSITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKEDI 10060

Query: 1364  KNKCTRLEFQVQ----KLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXX 1197
              ++ T+L+ ++     ++S++ E   TK +E ++    LEE +  + +M           
Sbjct: 10061 NHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKK 10120

Query: 1196  IRVRSLKKENTRLRSEMKG-ELTPSRSFKHREGSFIKEINIGDEDDTPLIQ 1047
              + +  ++E  R++ EM G EL   +S   RE S I        DD  +I+
Sbjct: 10121 EKEKEEEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKIIE 10171



 Score =  102 bits (254), Expect = 1e-18
 Identities = 187/905 (20%), Positives = 360/905 (39%), Gaps = 47/905 (5%)
 Frame = -3

Query: 3167 QTKVHIREEESCKHLTEALENHIYGSL------LESCVVDREAHIKQLMEQMNALVKEKR 3006
            Q + ++++E+    L E  +N     L      L+    + E   ++L   M+ L KEK 
Sbjct: 2479 QEESYVKKEKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKV 2538

Query: 3005 ELENDAQRGEEISQSLK-----------------DEVFQLKEV-SRLYEEEKQHTIELQE 2880
            E+  + QR  E+   +K                 D +   +E+ +R  E+ K+    L E
Sbjct: 2539 EITKEKQRVNEMQNEVKRKNASVDLIKQEVLREQDHIENSREILNRELEKIKEKKTILAE 2598

Query: 2879 NFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAV 2700
             F AL  K E I          +++   +  EL  + ++ E+QR  + ND ++ E+M   
Sbjct: 2599 EFEALDDKKEMI-------GKEMQRLGKMKAELQKEAEDTEKQRRDIDNDRRNNEEMVIK 2651

Query: 2699 SQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSR 2520
             Q E++++      +RD+  +L+        DR  +EK+  DLE  K             
Sbjct: 2652 LQNEKKDIETSTDRIRDEEANLRVQKQRLESDRDTLEKERFDLEKTK------------- 2698

Query: 2519 EQKLASDLKALSEKEESTKNQLLIQ-TEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEK 2343
                 +++K L ++ ES   Q  IQ  E  K+ E+ +E+L  +L  ++ +    +D  EK
Sbjct: 2699 -----TEMKDLEKQLESQSRQHEIQLVEIQKEREI-LEQLKINLSKQKEDLEKERDCFEK 2752

Query: 2342 IYDLCKLLATKSREVQGQQEGILKQDINIE---DELART-----KEVGRSATDMKKVNSD 2187
              +   +   +  E Q ++EGI K  + I+   DEL +T     KE+  +    K++  D
Sbjct: 2753 --EKADISLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNEL-QKQIIED 2809

Query: 2186 AGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEI 2007
               K+  I   L     D    ++++    N  RN+ +MV     ++Q+ K +       
Sbjct: 2810 ERDKIEQIKAELQKEAKDTEKQRQDI---ENDRRNNEEMV----IKLQNEKKD------- 2855

Query: 2006 RAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQ 1827
                   ++   D I+     L+   Q L+ +     KE ++ K     +      LESQ
Sbjct: 2856 -------IETSTDRIRDEEANLRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQ 2908

Query: 1826 NRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEIL 1647
            NR  + +L        +IQ+ER ++E     LS + E+L+ E ++  + E   + L E L
Sbjct: 2909 NRQHEIQL-------AEIQKEREILEQLKLTLSKQKEDLEKE-RDCFEKEKADISLREEL 2960

Query: 1646 LGQHVEVASLDIESCRFAEEKLMRILDELICLR-NENAKLKNEALY-EYHDYERKNVSGS 1473
              Q       + E       ++ + +DEL   R N   +L+N  L  +  + ER  +   
Sbjct: 2961 QEQS------EREGIGKTRVRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQI 3014

Query: 1472 RAEAMSVL---------ISKSLGNGRANQREFQNKEED-SSGVDLLKNKCTRLEFQVQKL 1323
            +AE              I K   N      + QN+++D  +  D ++++   LE Q Q+L
Sbjct: 3015 KAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLEVQKQRL 3074

Query: 1322 SEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK 1143
                +  E +  + ++   ++  +++ L               + R + ++     S+ K
Sbjct: 3075 ESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQK 3134

Query: 1142 GELTPSRS-FKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLM 966
             +L   R  F+  +       ++ ++ +   I              +TRT   QE+D L 
Sbjct: 3135 EDLEKERDCFEKEKADISLSEDLKEQSEREGID-------------NTRTRIKQEMDELE 3181

Query: 965  DDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKEL 786
               +       +   Q + +++   +++Q                        EK   EL
Sbjct: 3182 KTRQNLAKEQENNELQKKIIEDERDKIEQIKAEL---------------KKEAEKTKLEL 3226

Query: 785  NIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEEVPILCHQ-NSKIAERLD 609
                  L E  T+LKKD +   + A  +       + ++++ E+    ++ N ++ ER+ 
Sbjct: 3227 QNERQNLEEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVL 3286

Query: 608  INTDK 594
            I   K
Sbjct: 3287 IELKK 3291



 Score =  100 bits (250), Expect = 3e-18
 Identities = 156/811 (19%), Positives = 338/811 (41%), Gaps = 41/811 (5%)
 Frame = -3

Query: 3188 QKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMN----AL 3021
            Q +  +L+T++   ++E  K     +++     L +S +  ++ ++  ++E M      L
Sbjct: 3750 QDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLKQSELDKQQTNMNDIIETMKNERKQL 3809

Query: 3020 VKEKRELENDAQRGEEIS-------QSLKDEVFQLKEVSRLYEEEK----QHTIELQENF 2874
             K+K E+E   +  E+          SL +++  +K   +++EEEK    Q  IEL+   
Sbjct: 3810 DKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVFEEEKNKLEQMKIELEREA 3869

Query: 2873 NALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQ 2694
              +R+  E+I  + ++   + E+        +H  ++ ++++  L     + E + A  Q
Sbjct: 3870 GEIRKIKEEIQNERQSLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQ 3929

Query: 2693 TER---EELNRQLVLLRDDVNHLKEALSMAVDD----RAFMEKQLQDLENQKETVSKELA 2535
             E+   EE+   +    +DV + KE L +  D+    +A + KQ +++E +K  +  E A
Sbjct: 3930 KEKSNFEEMRENISKQTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERA 3989

Query: 2534 LSVSREQKLASDLKALSEKEESTK-------NQLLIQTEQNKQLEL---EIEKLYGSLQ- 2388
              +   + L   + +L    ES K       N+  +  +   +LE    EIEK+    Q 
Sbjct: 3990 AIIKIVEDLQHKIISLDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQH 4049

Query: 2387 MKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATD 2208
             +Q    +  D  E + +  K L     E+Q Q++ + K+  +++       +  +    
Sbjct: 4050 ERQRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKL 4109

Query: 2207 MKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSE 2028
             K+V  +   K+  +   L    D++  +KEE        +N+ Q ++   E+++  K  
Sbjct: 4110 QKQVIEEEKNKLEQMKIELEKEADEIRKIKEET-------QNERQRLEKMTEELKKEKES 4162

Query: 2027 LFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSK 1848
                AE    E   L     A + ++ +L+++   L++  +  +K+  +++     +  +
Sbjct: 4163 FTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLR 4222

Query: 1847 NINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYF 1668
               LE     L+AE+H Q     +I+ E++  ESE   +  +V++L+ ++          
Sbjct: 4223 EDELE----QLQAEIHKQQG---EIKMEKSNNESERAAIIKDVKDLQHKM---------- 4265

Query: 1667 LRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERK 1488
                   L + +E   LD E+     E L +I  +L     E  K+K E     HD +  
Sbjct: 4266 -----FSLDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIKLET---QHDRQ-- 4315

Query: 1487 NVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKC-TRLEFQVQKLSEKA 1311
                 R E M+  I K        + +  N  E+++  D++ N+  T ++ +++ +    
Sbjct: 4316 -----RVEEMTAQIQK-------ERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDR 4363

Query: 1310 EMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELT 1131
            +M E +  + ++  +KL   ++ L              I++  ++KE   L    +    
Sbjct: 4364 DMLEKEKHDLEKTRSKLLRAKENLEKQ---------RKIKLAEIQKEREDLEKMNEKFTI 4414

Query: 1130 PSRSFKHREGSFIKEINIGDEDDTPL------IQXXXXXXXXXXXKIDTRTSETQEIDTL 969
                 KH+E    ++ +  D+  T +      ++           ++D R SE  +  T 
Sbjct: 4415 EIHDIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTN 4474

Query: 968  MDDNRKYW-NRVSHFTKQTQSLQNSVQELQQ 879
            ++D  +   N      K  +  +   QE+++
Sbjct: 4475 VNDIMETMKNERKQLDKDKEETEEQKQEMEK 4505



 Score =  100 bits (249), Expect = 4e-18
 Identities = 150/756 (19%), Positives = 327/756 (43%), Gaps = 42/756 (5%)
 Frame = -3

Query: 3206 EDYYALQKKAGELQTKVHIREE-----ESCKHLTEALENHIYGSLLESCVVDREAHIKQL 3042
            ED     ++ G   T+  I++E     ++ ++L +  EN+    L +  + D    I+Q+
Sbjct: 3155 EDLKEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQENN---ELQKKIIEDERDKIEQI 3211

Query: 3041 MEQMNALV-KEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEE--EKQHTIELQENFN 2871
              ++     K K EL+N+ Q  EE    LK +    + V  L EE   KQ  +E  +   
Sbjct: 3212 KAELKKEAEKTKLELQNERQNLEEAGTKLKKD---RENVESLAEELGRKQVVLENMQIET 3268

Query: 2870 ALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQT 2691
             +++K         AN +  + ++ +++EL   + +    +  L+N +    + + V Q 
Sbjct: 3269 EMQRK---------ANESNKQMQERVLIELKKTVTDIAGAKEDLENQLLEEREKNKVKQA 3319

Query: 2690 EREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLE------------NQKETVS 2547
            E +     L LL+  ++  +  +    +     E +L+ L+            N+K  ++
Sbjct: 3320 EIQAEKDMLYLLKQGISEQQVDIVNKTEQLRLREVELEQLQALIYRQQDEIEANRKAIIN 3379

Query: 2546 KELAL-----SVSREQKLASDLKALSEKE----ESTKNQLLIQTEQNKQLELEIEKLYGS 2394
            ++  L      + R Q+  + +   + K+    E  K++++    Q  Q+++E+ K  G 
Sbjct: 3380 EKYRLEGQKTEIDRLQREVNQMMEYASKDRANLEKEKSEMI---AQKHQMDIELNKERGL 3436

Query: 2393 LQMK-QMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTK-EVGR 2220
            ++ + QM NT  K+ ++K       L  + +E++  ++ I ++    +++L + K E+ R
Sbjct: 3437 IEERTQMLNTYEKEMDQK----RTALEVEMKELKYHKQAIQEE----KNKLQQMKIELQR 3488

Query: 2219 SATDMKKVNS---DAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQ 2049
             A D+KK+     +    +  + E L   KDD+  L E+      + R D +M  +    
Sbjct: 3489 EADDIKKLKEKTRNERQSLEKMAENLEKEKDDLAHLAED------TKRKDDEMKVLHESA 3542

Query: 2048 MQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKAR 1869
            + D + E     ++R + + +    +D+ +  +I  + K Q +Q E  R   E+   K+ 
Sbjct: 3543 LADIQKEKCNLEQMR-ESMFKQNEMIDSEKKKMILREDKLQQMQAEINRQQTEMDTKKSI 3601

Query: 1868 LNNVMSKNINLESQNRSLKAELHLQAQKA-FQIQE---ERNVVESEHNVLSSEVENLKSE 1701
            + N   +   +  +N+ L  EL  Q++    Q++E   E+ ++ES+  +L  +VENL+ +
Sbjct: 3602 IEN---ERAAMTKKNQDLMTELTKQSEDVEIQMKEVLTEKELLESDRKLLKKDVENLQQK 3658

Query: 1700 LKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNE 1521
            L               +++    E    D E     +E L ++  +L     E  K+K E
Sbjct: 3659 L---------------LIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLE 3703

Query: 1520 ALYEYHDYERKNVSGSR----AEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKC 1353
              +E    E       +     + M+  I++ + + +  +++ + K+++   +D LK + 
Sbjct: 3704 TQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDE---LDQLKTEI 3760

Query: 1352 TRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKK 1173
              L+   Q+L ++ E+      E     ++L++ Q  ++D+             + ++K 
Sbjct: 3761 QNLQ---QELEKEKEIIMKDRSELDLKQSELDKQQTNMNDI-------------IETMKN 3804

Query: 1172 ENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDED 1065
            E  +L  + +      R  +  +  F +  N  DED
Sbjct: 3805 ERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDED 3840



 Score =  100 bits (248), Expect = 5e-18
 Identities = 144/703 (20%), Positives = 305/703 (43%), Gaps = 48/703 (6%)
 Frame = -3

Query: 3218 QKILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLM 3039
            +K+ E+   + +   ELQ + H   E+  + + +  E     +L +  V + E  +K+ M
Sbjct: 799  EKVKEELDEINRMRNELQRQ-HAEMEDWFRVVNKEKEE---ANLAKLAVHEAEMLLKKQM 854

Query: 3038 EQMNALVKEKRELENDAQRGEEISQSLKDEVFQL-KEVSRLYEE-EKQHTIELQENFNAL 2865
            E+     K + E+  +A    +  Q   +E+ Q+ KE+ R  +E EK    E +     L
Sbjct: 855  EESE---KRRYEMITEALEQRDEIQKKAEELEQINKEIQRARQELEKMRYFEKESLQKML 911

Query: 2864 RQKNEDICLKIEANNNLLEQK---DNIIVELSHKLQENEEQRSALQNDMQSVEQMH---- 2706
                ++     +  + LL+ K   D  + E+  + +E E+ R  ++N+ + +EQ      
Sbjct: 912  EDTQQERVFVEQVRSELLKNKADQDKCLFEMDSERKELEQMRFQVENEKKDLEQRRYEMM 971

Query: 2705 -------AVSQTEREELNR---QLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKE 2556
                   A  Q ++EEL +   QLV+  + +N  +E   +A  DR   E  + +++ Q+E
Sbjct: 972  RYDVEQSAQVQRQKEELEKIKSQLVIDTESMNRSRE---LARQDREKAELLIVEIQEQRE 1028

Query: 2555 TVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQT-----------EQNKQLELEIE 2409
             V+K L  +  RE+ L   L+   E E     ++ ++T           E+  ++  EIE
Sbjct: 1029 DVNKRLEETKQREEALRL-LRKDMENEREDLEKIRVETLRGKDTYEEVKEEINRVRAEIE 1087

Query: 2408 KLYGSLQM-KQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTK 2232
            +L+   +   Q E   +    E++    + +  +  E++  +  + KQ  NI+ ++   +
Sbjct: 1088 RLWDEAEKGDQEEREKINHEKEEMIRKMEAMKREMGEIEDMKVELTKQKENIDMKMEHAR 1147

Query: 2231 EVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALE 2052
                    ++  N          LEM   MK D+   KE++   + + +++ Q       
Sbjct: 1148 --------LEMTN----------LEM---MKADLLRQKEDIENQMLAAKSERQ------- 1179

Query: 2051 QMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKA 1872
            QM+  ++E+  + E   +++   +AE++ +QH+  E++++ + L++  Q+  +E+   + 
Sbjct: 1180 QMEVMRTEILKQKEDVERKMELAKAEMEKMQHVKDEIQKQRKELEERMQKTKREIGEMEL 1239

Query: 1871 RLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVE---SEHNVLSSEVENLKSE 1701
                +  K   L+ + +    +     +   +IQ  ++ +E    E      E+E +K+E
Sbjct: 1240 MKREMEGKKKELDQRMKLTMRKKEEMERLKMEIQRAKDDMEFKRVETERQKYEMEQVKAE 1299

Query: 1700 LKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNE 1521
            ++ ++  E + LR+ E  L +  E  +L I          + ++ ++   R    K K +
Sbjct: 1300 IQRAR--EEFELRVEERDLEEEKEQMNLTI----------INLIQQIEATREMVHKTKFQ 1347

Query: 1520 -------ALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKE---EDSSGVD 1371
                   +     D E  N    R   + +   + +  G   + E QNKE    D   + 
Sbjct: 1348 FENRMAGSQMGTADQEEMNAEMQRL-ILEIEHIREMLRGLKGEVE-QNKEIMKRDREEIR 1405

Query: 1370 LLKNKCTR----LEFQVQKLSEKAEMFETKSREAQQMANKLEE 1254
            LLK +  R    +E++ +K+  + +  E  S+  Q+   +LEE
Sbjct: 1406 LLKIEVQRRRREIEYREEKIMREQDELELMSKMGQRQREELEE 1448



 Score = 99.8 bits (247), Expect = 7e-18
 Identities = 160/769 (20%), Positives = 327/769 (42%), Gaps = 107/769 (13%)
 Frame = -3

Query: 3218  QKILEDYYALQKKAGELQTKVHIREEESCKHLTEAL---------ENHIYGSLLESCVVD 3066
             + +LED    +K+  E+  ++   +EE    ++E +         E  I    +E   ++
Sbjct: 12437 ESLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKIKQIEGEIKTKQIEMACLE 12496

Query: 3065  REAHIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIEL 2886
              E   K+L EQ N    E +EL+    R EE+++   +   +  E+ +L ++ ++   EL
Sbjct: 12497 -ELKQKELDEQKNMRECENQELQ---MRREELAKMKTEIDIERDEIQKLRKQYEKEKCEL 12552

Query: 2885  QENFNALRQKNEDICLKIEANNNLLEQKDNI---IVELSHKLQENEEQRSALQNDMQSVE 2715
             ++    L+++  +   KI+A      Q D I   I  L  + +E E+ ++ LQN ++  E
Sbjct: 12553 EQIKPDLQKREPE---KIDAE----VQHDEIHGGIDSLKEEREEIEKMKADLQNKLREAE 12605

Query: 2714  QMHAVSQTEREELNR------QLVL----------LRDDVNHLKEALSMAVDDRAFMEKQ 2583
              M  + + E++EL +      Q+ +          L+D++  ++  L +    + ++E+ 
Sbjct: 12606 NMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIEAILKVTKKQKNYLEQM 12665

Query: 2582  LQDLENQKETVSKELALSVSREQKLASDLKA-----LSEKEESTKNQLLIQ------TEQ 2436
              ++L  +K  +     +    + +L   +K      +S+ EE    +  I+       E+
Sbjct: 12666 NENLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKMEEREAERKTIERVMDEMAEE 12725

Query: 2435  NKQLELEIEKLYG-SLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDIN 2259
             +++++ E E+L     ++K+    L +  NE        +  K  E+Q ++  + KQ   
Sbjct: 12726 HEKIKKEREELVNMEEEIKKQRRVLEESMNE--------MTKKKSELQHERSELYKQKQQ 12777

Query: 2258  IEDELARTKEVGRSATDMKKVNSDAGAKVSGIL----EMLLPMKDDVFSLKEEVLGNINS 2091
             +ED +A       S  D+    S    +   IL    E +  MKD +   KE+V      
Sbjct: 12778 LEDMIA-----SESKRDVDTERSRQDKEDEQILKREREEIADMKDQLLKEKEDVETTKER 12832

Query: 2090  LRNDAQMVQVALEQMQDTKSE--------LFAEAEIRA---------QEVLRLQAEVDA- 1965
             +  + + ++    Q+ D K E        L+ + EI+          Q++ + +  V+A 
Sbjct: 12833 INREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEIQVKTNALEKMMQDLQKERENVNAL 12892

Query: 1964  -IQH---------ILIELKRKNQTLQDESQRNAKELWNAKARL----NNVMSKNINLESQ 1827
              IQH         ++ E KRK +  + E QR  +++ + K RL    N +   N  L+++
Sbjct: 12893 VIQHQKEREQRDILIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTR 12952

Query: 1826  NRSLKAELHLQAQKAF-----QIQEERNVVESEHNVLSSEVENLKSELKE----SKDLEG 1674
             +  L+  L  + QK F     ++Q ER  +E  +  L  +   LK+++++      DL+ 
Sbjct: 12953 SEELE-NLIKKQQKEFETKENEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQK 13011

Query: 1673  YFLRLFEILLGQHVEVASLDIESCRFAEEK---------LMRILDELICLRNENAKLKNE 1521
                +  E+      E + L  E  +  ++K         +   ++ L CLRNE    K  
Sbjct: 13012 EKNKTEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKS 13071

Query: 1520  AL----YEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKC 1353
              L     E H+ ++      ++E  S+   K       ++ E +  + D++   + K   
Sbjct: 13072 MLSRLSMEKHEIDKLKTE-IQSEKESIEEEKKTLKQLKDENESKRTQLDNT---IEKMNM 13127

Query: 1352  TRLEFQVQK---------LSEKAEMFETKSREAQQMANKLEEMQQTLSD 1233
              +L  Q +K         L  KAE  + + R+A Q+ +++ +  + L D
Sbjct: 13128 DKLSIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDD 13176



 Score = 99.4 bits (246), Expect = 9e-18
 Identities = 123/673 (18%), Positives = 301/673 (44%), Gaps = 72/673 (10%)
 Frame = -3

Query: 3047 QLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLK----EVSRLYEEEKQHTIELQE 2880
            + + Q   L   +   +++ +R E++  +++ ++ +++    E  +  +  +Q   E+++
Sbjct: 252  ETLRQQEELESNRESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLMEQMKAEIED 311

Query: 2879 NFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENE----EQRSALQNDMQSVEQ 2712
              N L +K EDI  + +    +      + +E+  +  E E    EQR+ +Q + + ++ 
Sbjct: 312  EKNELEKKKEDIKRQRDQFEQIKLDLQQVKMEMEQRWHETEKEGLEQRAVIQREKEQLKY 371

Query: 2711 MHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFM----------EKQLQDLENQ 2562
            +    Q  REE+ R     + +   + +  + A+++   +          EK L++++++
Sbjct: 372  LQDEIQRVREEVERNREFSKQEHARISQLRAQALEENNLIENKWHDILRKEKDLEEMKHE 431

Query: 2561 KETVSKELALS---VSRE----QKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKL 2403
             E   +EL ++   V +E    ++   D+++     E   +++  +TE+ K ++ E+++ 
Sbjct: 432  IERGREELVMNGELVKKEWEKIEQAKVDIQSHMISMEGRVDEIKRETERLKHIKTEMQRD 491

Query: 2402 YGSLQMKQMENT--LLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKE 2229
              +L+ KQ ++T    ++   K Y+    + T+  E + + +    +  NI  E+ R  +
Sbjct: 492  KDALE-KQKDDTRKAKEEAERKRYE----IVTEELEHRARLQRERDELENIRAEMQRVND 546

Query: 2228 VGRSATDMKK-------------------VNSDAGA---KVSGILEMLLPMKDDVFSLKE 2115
            V ++    +K                   VN++  A   +++   E +L  + ++  +K 
Sbjct: 547  VEKAKILKEKEESIRIREEARQERETTELVNAEIKAEKERLNQRQEEMLRERQEIERIKH 606

Query: 2114 EVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKR 1935
            E L     + N   +     E+M+  K+E+  + E   ++V  +Q   + ++   +EL+ 
Sbjct: 607  ETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKEQMEEAKVELEE 666

Query: 1934 KNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNR-------SLKAELHLQAQKAFQ 1776
            + + L+ +    ++E+  A+   N ++     +ES+ R        L+A+   + ++  +
Sbjct: 667  EREDLERKRDLVSREIEQAEFLRNEILRVKEEMESRWRETETEEVELRAKTQHELERLEK 726

Query: 1775 IQEE-----RNVVESEHNVL--SSEVENLKSELKESKD---LEGYFLRLFEILLGQHVEV 1626
            ++EE     +N+ ES+  ++     ++ LK E++E K    ++    +  E  L   +E 
Sbjct: 727  LREETERSQKNIEESKIELMLWKESLDKLKGEMEEDKHVVIMQMNEAKAKEEQLTMVIEQ 786

Query: 1625 ASLDIESCRFAEEKLMRILDELICLRNE----NAKLKNEALYEYHDYERKNVSGSRAEAM 1458
              ++      + EK+   LDE+  +RNE    +A++++       + E  N++       
Sbjct: 787  LEIERGEITISREKVKEELDEINRMRNELQRQHAEMEDWFRVVNKEKEEANLAKLAVHEA 846

Query: 1457 SVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSR--E 1284
             +L+ K +    + +R ++   E     D ++ K   LE Q+ K  ++A     K R  E
Sbjct: 847  EMLLKKQM--EESEKRRYEMITEALEQRDEIQKKAEELE-QINKEIQRARQELEKMRYFE 903

Query: 1283 AQQMANKLEEMQQ 1245
             + +   LE+ QQ
Sbjct: 904  KESLQKMLEDTQQ 916



 Score = 98.2 bits (243), Expect = 2e-17
 Identities = 146/778 (18%), Positives = 328/778 (42%), Gaps = 37/778 (4%)
 Frame = -3

Query: 3203 DYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNA 3024
            D   +++ A ++Q     +E +   +L E  E +    +L     D E  IK +    + 
Sbjct: 5183 DRQRVEEMAAQIQ-----KERDKINNLIE--ETNRKDMVLNEKNRDIEEKIKSIQSDKDM 5235

Query: 3023 LVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTI-ELQENFNALRQKNED 2847
            L KE+  LE             + E++++KE     E++K++T+ E+Q+    + + NE+
Sbjct: 5236 LEKERHNLEKT-----------RSELYKVKED---LEKQKENTLAEIQKEREDVEKMNEN 5281

Query: 2846 ICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQ 2667
            I  ++    +  EQ       ++ K  E ++ ++ +QN  Q +E+   +   +R + + +
Sbjct: 5282 ITREMHEIKHQEEQ-------MNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQFDLR 5334

Query: 2666 LVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKAL 2487
               L     ++ + +    ++R  ++K  +++E QK+ + KE        + L  DLK +
Sbjct: 5335 QSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKDLKMM 5394

Query: 2486 SEKE---ESTKNQLLIQTEQNK-QLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLL 2319
              ++   E  KN+L    EQ K +LE E +++    +  Q E   L+   E++    +  
Sbjct: 5395 KLQKQVFEEEKNKL----EQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESF 5450

Query: 2318 ATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMK 2139
               + + + +QE + K  +  E  +A  ++   +  +M++  S     V    E L   +
Sbjct: 5451 THLAEDTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLRE 5510

Query: 2138 DDVFSLKEE---------------------VLGNINSLRNDAQMVQVALEQMQDTKSELF 2022
            D+++ L+ E                     ++ N+  L++    +    E ++  +    
Sbjct: 5511 DELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFE 5570

Query: 2021 AEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNI 1842
             E E+  Q    L+ E D I+ I +E +   Q +++ + +  K+       +     K++
Sbjct: 5571 NEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDM 5630

Query: 1841 NLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLS---SEVENLKSELKESKDLEGY 1671
             L  +NR ++       +K   IQ +++++E E + L    SE+  +K +L++ K+    
Sbjct: 5631 VLNEKNRDIE-------KKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLA 5683

Query: 1670 FLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYH---- 1503
             ++     L +  E  + ++   +  EE++ +  DEL  L+ E   L+ E   E      
Sbjct: 5684 QIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMK 5743

Query: 1502 ---DYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQV 1332
                 +R+     + +     I +++ N R  ++  ++KEE       ++ +   ++   
Sbjct: 5744 ARSQLDRRQSELDKQQTNMNDIMETMKNER--KQLDKDKEEMEEQKQEMEKERDNMDQSR 5801

Query: 1331 QKLSEKAEMFETKSREAQQMANKLEEMQQTLS-DMXXXXXXXXXXXIRVRSLKKENTRLR 1155
            + L E  +M + + +  ++  NKLE+M+  L  +             + + L+K    L+
Sbjct: 5802 KSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELK 5861

Query: 1154 SEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQE 981
             E K     +   K RE + + E+ + +E     +Q            I  +T + ++
Sbjct: 5862 KERKDVAHLAEDTK-REKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEK 5918



 Score = 95.9 bits (237), Expect = 1e-16
 Identities = 192/1008 (19%), Positives = 398/1008 (39%), Gaps = 101/1008 (10%)
 Frame = -3

Query: 3227 AQHQKILEDYYALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVD--REA- 3057
            ++   I++D   LQ K   L      R+ ES K   EA EN     +L+    D  R+A 
Sbjct: 4249 SERAAIIKDVKDLQHKMFSLD-----RDLESLKLDREAFENE--REVLKQIKTDLKRKAE 4301

Query: 3056 ----------HIKQLMEQMNALVKEKRELEN----DAQRGEEISQSLKDEV---FQLKEV 2928
                      H +Q +E+M A ++++R+  N    +  R + +   +K E+    +  E 
Sbjct: 4302 EIEKIKLETQHDRQRVEEMTAQIQKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIES 4361

Query: 2927 SRLYEEEKQHTIE------LQENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQ 2766
             R   E+++H +E      L+   N  +Q+   +    +   +L +  +   +E+ H ++
Sbjct: 4362 DRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEKMNEKFTIEI-HDIK 4420

Query: 2765 ENEEQ-----------RSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALS 2619
              EEQ           ++ +QN  Q +E+   +   +R +L+ +   L     ++ + + 
Sbjct: 4421 HQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIME 4480

Query: 2618 MAVDDRAFMEKQLQDLENQKETVSKELALSVSREQKLASDLKALS------EKEESTKNQ 2457
               ++R  ++K  ++ E QK+ + KE        + L  DLK +       E E+S   Q
Sbjct: 4481 TMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQ 4540

Query: 2456 LLIQTEQN----KQLELEI-------EKLYGSLQMKQMENTLLKDGNEKIYD-------- 2334
            + I+ E+     ++++ EI       EK+  +L+ ++ +       N ++ D        
Sbjct: 4541 MKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANES 4600

Query: 2333 -LCKLLATKSREVQGQQEGILKQDINIEDE----LARTKEVGRSATDMKKVNSDAGAKVS 2169
             L  +L  KS  ++  +E I KQ  ++E++      R  E+ +   ++ K   +   +  
Sbjct: 4601 TLADILREKS-NLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKI 4659

Query: 2168 GILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVL 1989
             I      +  DV  L+ +++     L  DA+ +++  E  ++       E E+  Q   
Sbjct: 4660 NIESERAAIIKDVEDLQHKII----CLDRDAESLKLDREAFEN-------EKEVLKQMKT 4708

Query: 1988 RLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKA 1809
             L+ E D I+ I +E +   Q +++ + +  K+       +     K++ L  +NR ++ 
Sbjct: 4709 ELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIE- 4767

Query: 1808 ELHLQAQKAFQIQEERNVVESEHNVLS---SEVENLKSELKESKDLEGYFLRLFEILLGQ 1638
                  +K   IQ +++++E E + L    SE+  +K +L++ K+     ++     L +
Sbjct: 4768 ------EKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEK 4821

Query: 1637 HVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYE----YHDYERKNVSGSR 1470
              E  + ++   +  EE++ +  DEL  L+ E   L+ E   E      D  + ++  S 
Sbjct: 4822 MNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSE 4881

Query: 1469 AEAMSVLISKSLGNGRANQREF--------QNKEEDSSGVDLLKNKCTRLEFQVQKLSEK 1314
             +     ++  +   +  +++         + K+E     D +      L+   +K+  +
Sbjct: 4882 LDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQ 4941

Query: 1313 AEMFETKSREAQQMANKLE--------------EMQQTLSDMXXXXXXXXXXXIRVRSLK 1176
             +MFE +  + +QM  +LE                +Q L  M             +    
Sbjct: 4942 KQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREKESLAHLAEDT 5001

Query: 1175 KENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXXXXXXKIDTRT 996
            K   ++  EMK     S +   RE S ++E+          I            ++    
Sbjct: 5002 KTEKKILDEMKVANESSMADLQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQ 5061

Query: 995  SETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGIDM 816
            +E Q+  + +D  +   N  S      +  QN + EL++                     
Sbjct: 5062 TEVQKQQSKIDMEKT--NIESERAAMIREKQNMMTELKK-------------------KS 5100

Query: 815  NSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQKLKVDEEVPILCHQ 636
              +E Q+KE+      L      L +DV+        + DL    ++LK+D E      +
Sbjct: 5101 EDVEIQMKEILTEKELLHNDRKLLTRDVE---NLQQKLIDLERDSKRLKLDRE----AFE 5153

Query: 635  NSKIAER-----LDINTDKARALDMEVQRIRLILSRIPTKPTEEASKM 507
            N K A +     L I  D+   + +E Q  R  +  +  +  +E  K+
Sbjct: 5154 NEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKI 5201



 Score = 94.0 bits (232), Expect = 4e-16
 Identities = 136/733 (18%), Positives = 308/733 (42%), Gaps = 39/733 (5%)
 Frame = -3

Query: 3224  QHQKILEDYYALQK---KAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAH 3054
             + +K+ E+  +L++   K  E++TK    E E  K   E  E  +  + +E    + +  
Sbjct: 11203 KQKKMEEERKSLEETKIKIIEMKTKT---EPEKIKKEKEKEEEEVMRAKVEMKKEELDQI 11259

Query: 3053  IKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENF 2874
               QL    + +  E+++L +D +  E+  + L+      K  S + ++ +Q   E  E  
Sbjct: 11260 KSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLE------KMKSEIMKQRQQMEEERSELE 11313

Query: 2873  NALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQ------------------R 2748
             N +RQ   + C  IE +  ++++    + E  H++Q  +E+                  +
Sbjct: 11314 NKIRQTYIEKC-DIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNK 11372

Query: 2747  SALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLE 2568
             S LQN+ + ++ ++ V + ERE L      L  +   +K         +  +EK    + 
Sbjct: 11373 SELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSITEETRRQKEDLEKMSTHIN 11432

Query: 2567  NQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQ 2388
              QK+ +  +  L     +++    K L ++ +    Q+  Q E++   E E+++   SL+
Sbjct: 11433 EQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLE 11492

Query: 2387  MKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATD 2208
               +     +K   E             +E + ++E   +Q++ ++ E+ R KE+ +  + 
Sbjct: 11493 ETKANILEMKTKAEP--------EEIKKEKEKEEE---EQEMRVKVEMER-KEIEQIKSQ 11540

Query: 2207  MKKVNSDAG---AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDT 2037
             +++V S+      K++   +M+   K+D+  +K E++     +  +   +   ++Q    
Sbjct: 11541 LERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLE 11600

Query: 2036  KSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQ---RNAKELWNAKARL 1866
             K ++    EI  + ++ ++ +   IQ    EL  + Q + DE     +N  E  N   R+
Sbjct: 11601 KHDIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQQNENERI 11660

Query: 1865  NNVMSKNINLESQN-RSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKES 1689
                M + I  E +  + ++  L  + ++   + EE    + +   +S+++   K +L   
Sbjct: 11661 KE-MDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQ 11719

Query: 1688  KDL---EGYFLRLFEILLGQHVE--------VASLDIESCRFAEEKLMRILDELICLRNE 1542
             +DL   E   +      L Q ++        + +  +E     +EKL + + E   +  E
Sbjct: 11720 RDLLKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEYESIIEE 11779

Query: 1541  NAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLK 1362
               + + E      D  ++N      E M  L+ K   +    + E Q K+ D   + +++
Sbjct: 11780 TNRKRTELEEIEVDQSQQN---KNVETMKDLLEKERKDTEKEREELQ-KQADDLEMQMIE 11835

Query: 1361  NKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRS 1182
             +   + E   + L E+ ++ E K+ E  +  + LE+ ++   DM             +++
Sbjct: 11836 HG-DKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKE---DMMKKWNELDGLQKEIQN 11891

Query: 1181  LKKENTRLRSEMK 1143
              K E   ++ E++
Sbjct: 11892 QKNEMEEIKCELE 11904



 Score = 91.3 bits (225), Expect = 3e-15
 Identities = 150/725 (20%), Positives = 319/725 (44%), Gaps = 72/725 (9%)
 Frame = -3

Query: 3224  QHQKILEDYYALQK-KAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIK 3048
             + +++ ED  +L++ KA  L+ K     EE  K   +  E       +E    + E    
Sbjct: 11480 KEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIKS 11539

Query: 3047  QLMEQMNALVKEKRELENDAQRGEEISQSL---KDEVFQLK-----EVSRLYEEEKQHTI 2892
             QL    + +  E+++L +D +  E+  + L   K E+ + +     E S L ++ KQ  +
Sbjct: 11540 QLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDL 11599

Query: 2891  ELQENFNALRQKNEDICLKIEANNNLLE-QKDNIIVELSHKLQENE---EQRSALQNDMQ 2724
             E  +  N+ ++  E + +++E   + ++ QK+ + +E      E +   + +   QN+ +
Sbjct: 11600 EKHDIENS-KEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQQNENE 11658

Query: 2723  SVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSK 2544
              +++M    + ERE L    V L+ +   ++  +      +  +EK   D+  QK+ +  
Sbjct: 11659 RIKEMDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQKQDLMN 11718

Query: 2543  ELALSVSREQKLASDLKALSEK--EESTKNQLLI------QTEQNKQLELEIEKLYGSLQ 2388
             +  L     +++   L  L ++  E  T + +L+      +TE +++L+  I++    ++
Sbjct: 11719 QRDLLKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEYESIIE 11778

Query: 2387  MKQMENTLLKD-------GNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELAR--- 2238
                 + T L++        N+ +  +  LL  + ++ + ++E + KQ  ++E ++     
Sbjct: 11779 ETNRKRTELEEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQKQADDLEMQMIEHGD 11838

Query: 2237  TKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVA 2058
              +E+ + + D +K   +  A        +L  +DD+   KE+++   N L    + +Q  
Sbjct: 11839 KEEMSKRSLDEEKKLLEQKANE------ILRQRDDLEKEKEDMMKKWNELDGLQKEIQNQ 11892

Query: 2057  LEQMQDTKSELFAEAEIRAQEVLRLQAEVDAI-----------------QHILIELKRKN 1929
               +M++ K EL  +     +E  RL+  ++ +                 Q  + E++ K 
Sbjct: 11893 KNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKHQQQIEEMRVKT 11952

Query: 1928  QTLQDE-SQRNAKELWNAKARLNNVMSKNI------NLESQNRSLKA---ELHLQAQKAF 1779
             +  +DE  Q  AK L + K    N  SK++       +E    +L A   EL L+ QK  
Sbjct: 11953 KMERDELDQLMAKMLMDRK---ENERSKDMIGLLKKEMEQTKFNLDAQEEELKLEKQKIQ 12009

Query: 1778  QIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCR 1599
               +++  + ++E    +SEV+ LK +  E KD + +     E L GQ V+    + E  +
Sbjct: 12010 NEKKDLEMFKAEIKREASEVKTLKEQQLE-KDTKAFEALKEEHLPGQFVQQKGGEFERIQ 12068

Query: 1598  FAEEKLMRILDELICLRNENAKL-KNEALYEYHDYERKNVSGSR-AEAMSVLISKS---- 1437
               E K  RIL E   +  E  +L +N+ + E+       +   + +E + V++  S    
Sbjct: 12069 IDEVK--RILSE---IHKEKKELERNKQILEHQREALLEIKSKQPSERLDVILVSSATQT 12123

Query: 1436  -----LGNGRANQREFQNKEEDSSGVDLLKNKCTRL---EFQVQKLSEKAEMFETKSREA 1281
                  + +  A+Q E   K       D++K   T +   E+++ KL ++ +     +RE 
Sbjct: 12124 SDLEDIPDVSASQGETVEKH-----TDIIKEYTTSIPKEEYEIDKLKQQGDKKLKSTRED 12178

Query: 1280  QQMAN 1266
              +MA+
Sbjct: 12179 TKMAD 12183



 Score = 90.5 bits (223), Expect = 4e-15
 Identities = 175/913 (19%), Positives = 365/913 (39%), Gaps = 72/913 (7%)
 Frame = -3

Query: 3065 REAHIKQLMEQMNALVKE----KRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQH 2898
            RE  ++Q+  ++N    E    K  +EN+     + +Q L  E+ +  E   +  +E   
Sbjct: 3577 REDKLQQMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLT 3636

Query: 2897 TIELQENFNALRQKN-----------EDICLKIEANNNLLEQKDNIIVELSHKLQ----E 2763
              EL E+   L +K+           E     ++ +  LLE +  ++ ++   LQ    E
Sbjct: 3637 EKELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEE 3696

Query: 2762 NEEQRSALQNDMQSVEQMHAVSQTERE---ELNRQLVLLRDDVNHLKEALSMAVDDRAFM 2592
             E+ +   Q++ Q VE+M A  Q +RE   ++N  +     D+ + ++ +    D+   +
Sbjct: 3697 IEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDELDQL 3756

Query: 2591 EKQL----QDLENQKETVSK---ELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQN 2433
            + ++    Q+LE +KE + K   EL L  S   K  +++  + E  ++ + QL    E+ 
Sbjct: 3757 KTEIQNLQQELEKEKEIIMKDRSELDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEM 3816

Query: 2432 KQLELEIEK-----------LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQ 2286
            ++ + EIEK           L   L+M +++  + ++   K+  +   L  ++ E++  +
Sbjct: 3817 EEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIK 3876

Query: 2285 EGILKQDINIE---DELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKE 2115
            E I  +  ++E   +EL R KE      +  K   +   ++    E L+       S  E
Sbjct: 3877 EEIQNERQSLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEKSNFE 3936

Query: 2114 EVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDA---------- 1965
            E+  NI+    D +  +  L   +D   +L AE   + +E+ + ++ +++          
Sbjct: 3937 EMRENISKQTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVE 3996

Query: 1964 -IQHILIELKRKNQTLQ-----DESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAEL 1803
             +QH +I L R  ++L+      E++R   +    +        + I LE+Q+   + E 
Sbjct: 3997 DLQHKIISLDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHERQRVE- 4055

Query: 1802 HLQAQKAFQIQEERNVVESEHNVLSSEVENLKSEL-KESKDLEGYFLRLFEILLGQHVEV 1626
                +      E  N    + N    E++  K E+ KE  D++          L +++++
Sbjct: 4056 ----EMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMD-----QSRKSLDKNLKM 4106

Query: 1625 ASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLI 1446
              L  +     + KL ++  EL    +E  K+K E   E    E K     + E  S   
Sbjct: 4107 MKLQKQVIEEEKNKLEQMKIELEKEADEIRKIKEETQNERQRLE-KMTEELKKEKESF-- 4163

Query: 1445 SKSLGNGRANQREFQNK---EEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQ 1275
               L      +++  +K     +S   DL K K + LE   + +S++ E  E +  + + 
Sbjct: 4164 -THLAEDTKTEKKILDKMKVANESLMADLQKEK-SNLEEMRENISKQTEDSEKEKEKIRL 4221

Query: 1274 MANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSF 1095
              ++LE++Q  +                   +K E +   SE    +   +  +H+  S 
Sbjct: 4222 REDELEQLQAEIHKQQG-------------EIKMEKSNNESERAAIIKDVKDLQHKMFSL 4268

Query: 1094 IKEINI------GDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVS 933
             +++          E++  +++           +I+    ETQ       D ++     +
Sbjct: 4269 DRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIKLETQH------DRQRVEEMTA 4322

Query: 932  HFTKQTQSLQNSVQELQQXXXXXXXXXXXXXXKWGGI--DMNSIEKQLKELNIHVMQLVE 759
               K+   + N ++E  +              K   I  D + +EK+  +L     +L+ 
Sbjct: 4323 QIQKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLR 4382

Query: 758  HNTRLKKDVKFGFAWANSMHDLNGQEQKL-KVDEEVPILCHQNSKIAERLDINTDKARAL 582
                L+K  K   A      ++  + + L K++E+  I  H      E++    D+   L
Sbjct: 4383 AKENLEKQRKIKLA------EIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQL 4436

Query: 581  DMEVQRIRLILSR 543
              E+Q ++  L +
Sbjct: 4437 KTEIQNLQQELEK 4449



 Score = 89.0 bits (219), Expect = 1e-14
 Identities = 167/789 (21%), Positives = 333/789 (42%), Gaps = 127/789 (16%)
 Frame = -3

Query: 3218 QKILEDYYALQKKAGELQT-----KVHIREEESCKHLTEALENHIY--GSLLE------- 3081
            +K+ +++  L+KK  ++Q         I++ E+ + L E   N I     +LE       
Sbjct: 1853 EKLKQEWEELEKKRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNS 1912

Query: 3080 ----------SCVVDREAHIKQLMEQMNALVKEKRELENDA-QRGEEISQSLKDEVFQLK 2934
                      S +  RE  ++Q+   +N   KE ++++N       E+ +S  +   QLK
Sbjct: 1913 QQKDEIENEKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQDEIAEQLK 1972

Query: 2933 EVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEAN-----NNLLEQKDNIIVELSHKL 2769
            +V  +     Q T   ++N +  R    +  L++E +     N  LE    +  E+ ++ 
Sbjct: 1973 QVGDMM----QFTQNEKDNLDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEK 2028

Query: 2768 QENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDR---- 2601
            +  E+ R +L  DMQ +EQM    + E+EE+  Q   + ++ + L+  L    +D     
Sbjct: 2029 RLLEDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLR 2088

Query: 2600 --AFMEKQ-LQD--LENQKETVS-KELALSVSREQKLASDLKALSEKEEST--------K 2463
                 EKQ L+D  +E QKE      +A    R+++    ++   EK+E T        +
Sbjct: 2089 IDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIRVGIEKQEITFKDLKADLQ 2148

Query: 2462 NQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQE 2283
             +  I   Q + ++ +I+ +       Q E   +    E+I    K L     EV  +++
Sbjct: 2149 KEAAIVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVDKERQ 2208

Query: 2282 GILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKV---SGILEML---LPMKDDVFSL 2121
             +  +   +E E ++ +E     +  K+ N+   A++   S  LE+    +  +  +F L
Sbjct: 2209 EVESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTIFEL 2268

Query: 2120 KEEVLG-----------NINSLRNDAQMVQVALEQMQDTKSELFAEAEI----------- 2007
            ++E LG            I+ L+N  +M +V +EQMQ  K +   +AE            
Sbjct: 2269 EKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTARGRETTA 2328

Query: 2006 ---RAQEVLRLQAEVDAIQ----HI-----LIELKRKNQTLQDESQRNAKELWNAK---- 1875
               + QE+  L+ E + ++    H+     L E + K+  +++E+ +  KE  + +    
Sbjct: 2329 LEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKYKEKLDKEYEDL 2388

Query: 1874 -------ARLNNVMSKNINLESQN-RSLKAELHLQA----QKAFQIQEERNVVE-SEHNV 1734
                    +    M   + +E++N    K EL +Q      + + ++ ++ VVE S+ + 
Sbjct: 2389 QFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDE 2448

Query: 1733 LSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELIC 1554
            L    + + ++L E +  +   +++  + + Q       + +  +  E +    + +L  
Sbjct: 2449 LDEVRKKINADLSEVEKQKSALVQM-NLKISQEESYVKKEKDRLKLQENEQNMQMSQLNA 2507

Query: 1553 LRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGV 1374
             +NE    + +A  E    E +NV   R E   V I+K     R N+ + + K +++S V
Sbjct: 2508 KQNELD--ERQAEMEKQKRELENVM-DRLEKEKVEITKE--KQRVNEMQNEVKRKNAS-V 2561

Query: 1373 DLLKNKCTR-----------LEFQVQKLSEK----AEMFETK-------SREAQQMANKL 1260
            DL+K +  R           L  +++K+ EK    AE FE          +E Q++    
Sbjct: 2562 DLIKQEVLREQDHIENSREILNRELEKIKEKKTILAEEFEALDDKKEMIGKEMQRLGKMK 2621

Query: 1259 EEMQQTLSD 1233
             E+Q+   D
Sbjct: 2622 AELQKEAED 2630



 Score = 87.8 bits (216), Expect = 3e-14
 Identities = 169/961 (17%), Positives = 387/961 (40%), Gaps = 86/961 (8%)
 Frame = -3

Query: 3173  ELQTKVHIREEESCKHLTEALENHIYGSLLESCVV-DREAHIKQLMEQMNALVKEKRELE 2997
             +++  +  +EE   K   E    H    L+++ VV  +E  +KQ +E    + +EK++L+
Sbjct: 7284  DIRRNLFKKEEAIEKDKAEIRLRHQELDLIQAKVVKQKEEMVKQKIESEREIQQEKKKLQ 7343

Query: 2996  NDAQRGEEISQSLKDEVFQLKEVS-------RLYEEEKQHTIELQENFNALRQKNEDICL 2838
                +  E+  Q +K E+ +LK +        +  + + +     ++    ++   E    
Sbjct: 7344  RSEEELEDKMQKIKREMIELKLLQDETDGKRKDVDNKMRQVARKRDELEKMKADVESASK 7403

Query: 2837  KIEANNNLL------------------EQKDNIIVELSHKLQENEEQRSALQNDMQSVEQ 2712
             K+E +  +L                  E   +   E +  L E E   + +Q  +Q  E+
Sbjct: 7404  KLEVDRVMLNTERDELERIKTESQRATEHMQSHAEERAGDLGEKEPVNTRIQRLIQEAEK 7463

Query: 2711  MHAVS--------------------QTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFM 2592
                ++                      ER++++  +  +  ++ H +E L    D+    
Sbjct: 7464  ASKMAWSTKHEPEMRMQREVSVEEESVERQDMSANMQRMILEIEHARETLRGMKDEVQAA 7523

Query: 2591  EKQLQDLENQK-ETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQN----KQ 2427
              K+  +LEN K E ++ +  +  + EQ+   + +   EK++   +++L+  E+N     +
Sbjct: 7524  RKERSELENMKLEFLTMKKNMEKTYEQQ---NDEIQKEKQQIESSKMLLSRERNDLEQNR 7580

Query: 2426  LELEIEKLYGSLQMKQM--ENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIE 2253
              +LE +K   +L  +++  EN LL+     +  + + L +   E   ++     Q    +
Sbjct: 7581  ADLERQKQIMALDKQKLLAENELLEREKADVIKIIENLESLREEATRERATETAQATRRD 7640

Query: 2252  DELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQ 2073
              E    K    S  D ++ + +   ++   ++ L+ +K D+   + E+      L+   Q
Sbjct: 7641  SEELMQKMEALSMEDFQEASKNQMVELKRQIDKLIELKADLLQQQTELKKTKADLKQ--Q 7698

Query: 2072  MVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVD----AIQHILIELKRKNQTLQDESQ 1905
             M  +   + +  K E   +++ R  E++ +Q + D     IQ + +E KR  + L+ E  
Sbjct: 7699  MDDLEKTRSEILKHEKDTDSKTRELELIEIQRQKDDLETRIQKLTLE-KRDLEVLRSEIV 7757

Query: 1904  RNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSS 1725
                K+L     ++     +   + S   +   E++ + Q+   ++        +  +L  
Sbjct: 7758  LEKKDLDQKMKQVIRKRDEMEKIRSDIANATEEINRERQELEILRNNVQSARHDFELLLE 7817

Query: 1724  EVENLKSELKESKDLEGYFLRLFEIL---------LGQHVEVASLDIESCRFAEEKLMRI 1572
                NL+ E   + D+E   L + +I          + + +E + ++I+     + ++ R 
Sbjct: 7818  RTANLEDEESAATDIERLVLEVVKIREMVRNLKGEMERRMEKSKVEIDEKEIFKSEIQRF 7877

Query: 1571  LDELICLRNENAKLKNEALYEYHDYERKNVSGSRA---------EAMSVLISKSLGNGRA 1419
             + ++  +R     L  E   E    +++ +   RA         E+M  ++ K       
Sbjct: 7878  IQDIGQIRENLGGLGEE--IEKTRRDKRELEKMRAELAEKQQEQESMREMLHKEREELEQ 7935

Query: 1418  NQREFQNKEED----SSGVDLLKNKCTRLEF-QVQKLSEK----AEMFETKSREAQQMAN 1266
              + E   ++ED       V+ + +K    EF  +QK  E+     E   TK R+  Q+ +
Sbjct: 7936  LKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNS 7995

Query: 1265  KLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKE 1086
              +++++QT+ ++             +    K+  +L  + K EL        +E  +I E
Sbjct: 7996  DVQDLRQTIEEINIQHGKKRAELEGIGFELKKGEQLLEKQKDEL--------KENGWIVE 8047

Query: 1085  INIGDEDDTPLIQXXXXXXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSL 906
               I ++ D+  ++            +D    + ++    MD  R      S   +Q + L
Sbjct: 8048  -EIKNKKDS--LEKINMEILRKNEDMDKEKGKLRQEKQEMDLFR------SELQRQREDL 8098

Query: 905   QNSVQELQQXXXXXXXXXXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKF 726
             + S+Q+L                    +  + I  + K+L+  + Q++     ++   K 
Sbjct: 8099  ETSIQKLTHEKREME------------VLRSEIVLEKKDLDQKMKQVIRKRDEME---KI 8143

Query: 725   GFAWANSMHDLNGQEQKLKV-DEEVPILCHQNSKIAER-LDINTDKARALDMEVQRIRLI 552
              F  AN+  +++G+ Q+L++  + V        ++ ER  ++  +++ A D+E    RL+
Sbjct: 8144  RFDIANARVEIDGERQELEILRDNVQSARQDFERLVERTANLEVEESAATDIE----RLV 8199

Query: 551   L 549
             L
Sbjct: 8200  L 8200



 Score = 86.3 bits (212), Expect = 8e-14
 Identities = 175/980 (17%), Positives = 406/980 (41%), Gaps = 56/980 (5%)
 Frame = -3

Query: 3224  QHQKILEDYYALQK---KAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAH 3054
             + +K+ E+  +L++   K  E++TK    E E  K   E  E  +  + +E    + +  
Sbjct: 10925 KQKKMEEERKSLEETKIKIIEMKTKT---EPEKIKKEKEKEEEEVMRAKVEMKKEELDQI 10981

Query: 3053  IKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENF 2874
               QL    + +  E+++L +D +  E+  + L+    ++ +  +  EEE+       +  
Sbjct: 10982 KSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQT 11041

Query: 2873  NALR---QKNEDICLKI-----EANNNLLEQKDNIIVELSHKLQENE---EQRSALQNDM 2727
             +  R   + +++I  K+     E   ++  QK+ + +E      E     + ++ LQN+ 
Sbjct: 11042 DLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNEN 11101

Query: 2726  QSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVS 2547
             + +++M    + E+E L      LR +    KE +   +++     +Q +DLE     V+
Sbjct: 11102 ERIKEMDEEIKKEKETLKEMEAHLRKE----KEEMRSVIEET--QRRQKEDLEKMSTDVN 11155

Query: 2546  KELALSVSREQKLASDLKALSEKEESTKNQL-LIQTEQNKQLELEIEKLYGSLQMKQMEN 2370
             K+    +++   L  + + ++ K    + ++     + +KQ E ++ K       K+ME 
Sbjct: 11156 KQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTK------QKKMEE 11209

Query: 2369  TLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTK------EVGRSATD 2208
                     KI    K++  K++    + E I K+    E+E+ R K      E+ +  + 
Sbjct: 11210 ERKSLEETKI----KIIEMKTKT---EPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQ 11262

Query: 2207  MKKVNSDAG---AKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDT 2037
             +++V S+      K++   +M+   K+D+  +K E++     +  +   ++  + Q    
Sbjct: 11263 LERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIE 11322

Query: 2036  KSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQ---RNAKELWNAKARL 1866
             K ++    EI  + ++ ++ +   IQ    EL  + Q + DE     +N  EL N   R+
Sbjct: 11323 KCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERI 11382

Query: 1865  NNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESK 1686
              N+           + ++A L  + ++   I EE    + +   +S+ +   K +L+  +
Sbjct: 11383 KNINEVIKKERETLKEMEAYLEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQR 11442

Query: 1685  DLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNENAKLKNEALYEY 1506
             DL                     + E      ++L + +DE      + +K K E L + 
Sbjct: 11443 DL------------------LEQEREEINHKWKQLQQRIDEFDA---QVSKQKEEDLPKE 11481

Query: 1505  HDY--ERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDS----------SGVDLLK 1362
              +   +RK++  ++A   ++L  K+       ++E + +EE+             ++ +K
Sbjct: 11482 KEMKEDRKSLEETKA---NILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIK 11538

Query: 1361  NKCTR----LEFQVQKLSEKAEMFETKSREAQQMANKL----EEMQQTLSDMXXXXXXXX 1206
             ++  R    ++ + +KL++  +M E +  + ++M +++    ++M++  S++        
Sbjct: 11539 SQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTD 11598

Query: 1205  XXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXXXXX 1026
                  + + K+   +L  E++ +    +    +E   I+   I DE D  LIQ       
Sbjct: 11599 LEKHDIENSKEIVEKLMVEVEKQKHEIQF--QKEELDIERQKIADEQDL-LIQNKIEQ-- 11653

Query: 1025  XXXXKIDTRTSETQEIDTLMDDNRKYWNRVS-HFTKQTQSLQNSVQELQQXXXXXXXXXX 849
                          +E+D  +   R+    +  +  K+ + +++ ++E Q+          
Sbjct: 11654 ------QNENERIKEMDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMST 11707

Query: 848   XXXXKWGGI--DMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQK 675
                 +   +    + ++++ +E+N  + QL +       +          M +    ++K
Sbjct: 11708 DINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEF--ETTSNILVTTKMEEKTEMDEK 11765

Query: 674   LK--VDEEVPILCHQNSKIAERLDINTDKARA-LDMEVQRIRLILSRIPT-KPTEEASKM 507
             L+  + E   I+   N K  E  +I  D+++   ++E  +  L   R  T K  EE  K 
Sbjct: 11766 LQQAIKEYESIIEETNRKRTELEEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQKQ 11825

Query: 506   RVPLRAFLV--GSKKDQSKR 453
                L   ++  G K++ SKR
Sbjct: 11826 ADDLEMQMIEHGDKEEMSKR 11845



 Score = 85.9 bits (211), Expect = 1e-13
 Identities = 123/648 (18%), Positives = 278/648 (42%), Gaps = 48/648 (7%)
 Frame = -3

Query: 3053 IKQLMEQMNALVKEKR-ELEN---DAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIEL 2886
            ++Q +E++N    +KR ELE    + ++GE++ +  KDE   LKE   + EE K     L
Sbjct: 8000 LRQTIEEINIQHGKKRAELEGIGFELKKGEQLLEKQKDE---LKENGWIVEEIKNKKDSL 8056

Query: 2885 QENFNALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMH 2706
            ++    + +KNED+  +        ++ D    EL  + ++ E     L ++ + +E + 
Sbjct: 8057 EKINMEILRKNEDMDKEKGKLRQEKQEMDLFRSELQRQREDLETSIQKLTHEKREMEVLR 8116

Query: 2705 AVSQTEREELN---RQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELA 2535
            +    E+++L+   +Q++  RD++  ++  ++ A  +     ++L+ L +  ++  ++  
Sbjct: 8117 SEIVLEKKDLDQKMKQVIRKRDEMEKIRFDIANARVEIDGERQELEILRDNVQSARQDFE 8176

Query: 2534 LSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKD 2355
              V R   L  +  A ++ E      + I+ E  + L+ E+E+     +++  E  + K 
Sbjct: 8177 RLVERTANLEVEESAATDIERLVLEVVKIR-EMVRNLKGEMERRMEESKVEIDEKEIFKS 8235

Query: 2354 GNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAK 2175
              +++      +      ++ + E   +   N+E   A  +E  +    M+++      +
Sbjct: 8236 EIQRLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQEEESMREILQKEKEE 8295

Query: 2174 VSGILEMLLPMKDDVFSLKEEVLGNI--------NSLRNDAQMVQVALEQMQDTKSELFA 2019
            +  + + +   K+D+   +E V   I          ++   + +Q+  E++  TK     
Sbjct: 8296 LEQLKKDINREKEDIEISRELVESEIYEGEVKGFTDVQKYKEELQIVTEELL-TKKRNLE 8354

Query: 2018 EAEIRAQEVLRLQAEVD--------AIQHILIELKRKNQTLQDESQRNAKELW------N 1881
            +     Q +++   EVD         ++HI  E++++ Q L+ + ++  +  W       
Sbjct: 8355 QLNSDVQHLMQTLEEVDIQYIKKKAELEHITSEIQKREQILEKQKKKLEENGWIIEEIEM 8414

Query: 1880 AKARLNN----VMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVEN 1713
             K  L +    ++ K  ++E +  +L+ E         ++Q +R+ VES    L  E + 
Sbjct: 8415 MKVTLESINMEILQKREDMEKEKENLRREKQETELFRGELQRQRDEVESSRQALIMEKDQ 8474

Query: 1712 LKSEL------------KESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRIL 1569
             K ++            KE K LE     +   L  Q  ++A   +      E+KL ++ 
Sbjct: 8475 FKLKIDHQRNEMSAAFEKEHKRLE----NMENDLENQRAKLAE-SLNDAAKMEQKLQQMK 8529

Query: 1568 DELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQR-EFQNK- 1395
            +EL        K + E + +    ER  +   + E          G+ +  ++ E  +K 
Sbjct: 8530 NEL-----NKEKEQVEEMKQMVKTERVKIEQEKEEMRKQTQEIEDGHEKLQKKTEIADKL 8584

Query: 1394 -EEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEE 1254
             ++ +S  D LK+   +L+ Q Q + +     ETK R   +M+ +L++
Sbjct: 8585 LQDANSESDRLKDLSMKLQMQRQDIEKTNTEMETKKRSLDRMSRELQD 8632



 Score = 84.7 bits (208), Expect = 2e-13
 Identities = 127/667 (19%), Positives = 290/667 (43%), Gaps = 10/667 (1%)
 Frame = -3

Query: 3209 LEDYYALQKKAGELQ-TKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQ 3033
            LE+  A  ++  +++  K+   +EES +   EA +      L+ + +   +  + Q  E+
Sbjct: 534  LENIRAEMQRVNDVEKAKILKEKEESIRIREEARQERETTELVNAEIKAEKERLNQRQEE 593

Query: 3032 MNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVS-RLYEEEKQHTIELQENFNALRQK 2856
            M   ++E++E+E    R +  +   K+E+   ++V+ R YE+ ++   E+Q         
Sbjct: 594  M---LRERQEIE----RIKHETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQI------ 640

Query: 2855 NEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREEL 2676
             EDI  K+E      EQ +   VEL  + ++ E +R  +  +++  E +       +EE+
Sbjct: 641  -EDIEKKVEEIQKTKEQMEEAKVELEEEREDLERKRDLVSREIEQAEFLRNEILRVKEEM 699

Query: 2675 NRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLEN-QKETVSKELALSVSREQKLA-- 2505
                       +  +E  +  V+ RA  + +L+ LE  ++ET   +  +  S+ + +   
Sbjct: 700  E----------SRWRETETEEVELRAKTQHELERLEKLREETERSQKNIEESKIELMLWK 749

Query: 2504 SDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCK 2325
              L  L  + E  K+ +++Q  + K  E ++  +   L++++ E T+ ++  ++  D   
Sbjct: 750  ESLDKLKGEMEEDKHVVIMQMNEAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEIN 809

Query: 2324 LLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDM--KKVNSDAGAKVSGILEML 2151
             +  + +    + E   +  +N E E A   ++     +M  KK   ++  +   ++   
Sbjct: 810  RMRNELQRQHAEMEDWFRV-VNKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEA 868

Query: 2150 LPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEV 1971
            L  +D++    EE    +  +  + Q  +  LE+M+  + E   +     ++  + +  V
Sbjct: 869  LEQRDEIQKKAEE----LEQINKEIQRARQELEKMRYFEKESLQKM---LEDTQQERVFV 921

Query: 1970 DAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQA 1791
            + ++  L++ K        E     KEL   + ++ N   +  +LE +   +   +    
Sbjct: 922  EQVRSELLKNKADQDKCLFEMDSERKELEQMRFQVEN---EKKDLEQRRYEM---MRYDV 975

Query: 1790 QKAFQIQEERNVVESEHNVLSSEVENL-KSELKESKDLEGYFLRLFEILLGQHVEVASLD 1614
            +++ Q+Q ++  +E   + L  + E++ +S     +D E   L + EI   +  E  +  
Sbjct: 976  EQSAQVQRQKEELEKIKSQLVIDTESMNRSRELARQDREKAELLIVEIQ--EQREDVNKR 1033

Query: 1613 IESCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYE--RKNVSGSRAEAMSVLISK 1440
            +E  +  EE L  +  ++   R +  K++ E L     YE  ++ ++  RAE   +    
Sbjct: 1034 LEETKQREEALRLLRKDMENEREDLEKIRVETLRGKDTYEEVKEEINRVRAEIERLWDEA 1093

Query: 1439 SLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKL 1260
              G+    ++    KEE    ++ +K +   +E    +L+++ E  + K   A+     L
Sbjct: 1094 EKGDQEEREKINHEKEEMIRKMEAMKREMGEIEDMKVELTKQKENIDMKMEHARLEMTNL 1153

Query: 1259 EEMQQTL 1239
            E M+  L
Sbjct: 1154 EMMKADL 1160



 Score = 84.7 bits (208), Expect = 2e-13
 Identities = 143/733 (19%), Positives = 308/733 (42%), Gaps = 76/733 (10%)
 Frame = -3

Query: 3203 DYYALQKKAGELQTKVHI--REEESCKHLTEALENHIYGSLLESCVVDREAHIKQ----L 3042
            D   L+K   +LQ K+    R+ ES K   EA EN            ++EA +KQ    L
Sbjct: 6253 DRNLLKKDVEDLQQKLMSIERDSESLKLDKEAFEN------------EKEA-MKQMKTDL 6299

Query: 3041 MEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNALR 2862
              Q + + K K E  ++ QR EE +  ++ E    +E++ L EE K+    + E++  +R
Sbjct: 6300 QIQADEIEKIKLETHHERQRVEEKTAQIQKE---REEINTLVEEIKKKRDIIDESYTEIR 6356

Query: 2861 QKNEDI-----------CLKIEANNNL------LEQKDNIIVELSHKLQEN----EEQRS 2745
            ++ E I               + N N+      ++QK N + ++S ++  +    E+++ 
Sbjct: 6357 KEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQQKRNALEKMSKEISRDRMKLEDEKK 6416

Query: 2744 ALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVD----DRAFMEKQLQ 2577
             +Q   + +E+MH   Q ++E  +  L  + D+    K    + +     D+A   ++ +
Sbjct: 6417 EIQLAREELERMHGDMQRQQEAKDHLLSGITDESLLKKSEAEIVLQPSQVDKAKPARKTE 6476

Query: 2576 DLENQKETVSKELALSVSREQKLASDLKA-----------LSEKEESTKNQLLIQTEQNK 2430
              ++ K+ V  +    +  +  L  D ++           L + ++    Q LI+ E +K
Sbjct: 6477 ISDSDKQPVFVQQMPEMDLKDALKKDFESEKLDLPKVKDVLPQDQQMKLEQKLIEDEMDK 6536

Query: 2429 --QLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINI 2256
              Q+  E++K    ++ K+ +   +++  +K+ D+   L  + R  +   E I  Q +N 
Sbjct: 6537 LKQMRAELQKEADQIEKKKQD---MQNERQKLDDMAARLQEERRTNERLNEEINIQKVNQ 6593

Query: 2255 EDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDA 2076
            + +    +      TD +++ ++       + +     K  +  +++E         N +
Sbjct: 6594 QKQATAFQ---MEKTDFERIKTEIDQANKELADQQEKNKKTITEMQKERETLEEMRANIS 6650

Query: 2075 QMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQH-ILIELKRKNQT-------- 1923
            + V+    + +   S     A+++ +++L+ Q E+D +++ I++E+ + +Q         
Sbjct: 6651 KQVETITNENKSLSSRESELAKLQ-EDILQQQQEMDELKNTIMMEMCQLDQRQSDIDLLQ 6709

Query: 1922 --LQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVE 1749
              + D       E+ N +     V+++  N++S   SLK E     Q   ++ EE++++E
Sbjct: 6710 KEVDDLMDFTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNEEKDLIE 6769

Query: 1748 SEHNVLSS--------------EVENLKSELK----ESKDLEGYFLRLFEILLGQHVEVA 1623
             E  +L+               E+ENLK E +    E K+LE   + L    +G   E +
Sbjct: 6770 KERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKELEKMKISLQRKAIG-FKEFS 6828

Query: 1622 SLDIESCRFAEEKLMRILDEL-ICLRNENAKLKNEALYEYHDYERKN-VSGSRAEAMSVL 1449
                +     EE   +   +L I  R    K   E L +     RK   +    +     
Sbjct: 6829 EKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQTEKKRRKTYYTEDLFQEEKTD 6888

Query: 1448 ISKSLGNGRANQRE-FQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQM 1272
            + K+      ++ E ++ + E +   + LK   T    +++ + ++ E  +    E  Q+
Sbjct: 6889 LQKTKEEINYDREEIYRQRTELNKEKETLKQMHTSNLKEIENIEKEKEKIQRTWNELDQI 6948

Query: 1271 ANKLEEMQQTLSD 1233
              +L+  Q+ + D
Sbjct: 6949 RAELQNKQRDMDD 6961



 Score = 84.7 bits (208), Expect = 2e-13
 Identities = 172/842 (20%), Positives = 348/842 (41%), Gaps = 61/842 (7%)
 Frame = -3

Query: 3224  QHQKILEDYYA-LQKKAGELQTKVHI-----REEESCKHLTEALENHIYGSLLESCVVDR 3063
             + +K LE   A L++K+ EL+ K+        + +  K+ TE L+N +     E  +   
Sbjct: 12976 RERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREKSE--LYQE 13033

Query: 3062  EAHIKQLMEQMNALVKE-KRELENDAQRGEEISQSLKDEVFQLK----EVSRLYEE---E 2907
             +A ++Q   +M  + K  K E+EN      E+    K  + +L     E+ +L  E   E
Sbjct: 13034 KAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTEIQSE 13093

Query: 2906  KQHTIELQENFNALRQKNEDIC--------------LKIEANNNLLEQKDNIIVELSHKL 2769
             K+   E ++    L+ +NE                 L I+   + LE+   I  +L  K 
Sbjct: 13094 KESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLSIQREKDSLEE---IKADLQRKA 13150

Query: 2768  QE-NEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFM 2592
             ++ +EE R A+Q   Q               +++   +L DD    +E  SM    RA +
Sbjct: 13151 EKLDEEMRKAVQITSQ---------------ISQDAKILDDDREKEEELRSM----RADI 13191

Query: 2591  EKQLQDLENQKETVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEI 2412
             E+Q + LE+  + +  E    +  + K  +DL     +++  +N L +Q       EL  
Sbjct: 13192 ERQAKILESDVQLLQTE--KEILEKSKTENDLLREDLEKQRKRNDLTLQ-------ELRK 13242

Query: 2411  EKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTK 2232
             EK    + ++QM   + K+  + +  L   ++ K  E++ ++  + +Q   + D+L    
Sbjct: 13243 EK----MALEQMITDITKE-KDAVASLQNEVSLKQHELKNKETELDEQRKEM-DDLRMQL 13296

Query: 2231  EVGRSATDMKKVNSDA----GAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQ 2064
             E+ +++T+ ++   D       K+   LE +  + D+     ++ +      +N     +
Sbjct: 13297 EMRQNSTNKQQQEVDVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSK 13356

Query: 2063  VALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELW 1884
                 Q  D   +   + +   + V + + E+D +   +I+ K + Q+L  E +   +E+ 
Sbjct: 13357 TDAVQQTDELEKFTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIA 13416

Query: 1883  NAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKS 1704
               +A++ ++     +L +    +K  +  + Q A +  E++  VE + N+   + +N   
Sbjct: 13417 GKRAQIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNL--QKQKNELE 13474

Query: 1703  ELKESKDLEGYFLRLFEILLG---QHVEVASLDIESCRFAEEKLMRILDELICLRNENAK 1533
             EL+ + + E + +   +I+L    + VE     I+S R   EK    L++L  + NE  +
Sbjct: 13475 ELRNTIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQ 13534

Query: 1532  LKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDLLKNKC 1353
              + E L    + ER ++   +    S    +S+   RA  +  + + E      LL+   
Sbjct: 13535 REQEELERLLEKERDDIENCKKIIESE--KQSIERERAELKRLKEEVEVQHERTLLQQDK 13592

Query: 1352  TRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVR---- 1185
               ++       EK  +   K+R  +++ N  EE+++  S++                   
Sbjct: 13593 NMIQ------KEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQEEELHGL 13646

Query: 1184  --------SLKKENTRLRSEM--KGELTPSRSFKHREGS-------FIKEINIGDEDDTP 1056
                      LKKE+  LR E+  K +   S+ F+ +  S        + EI   DE    
Sbjct: 13647 PEEIEIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDEITKTDERRQR 13706

Query: 1055  LIQXXXXXXXXXXXKI---DTRTSETQEIDTLMDDNRKYWNRVSHFTK-QTQSLQNSVQE 888
              ++            I   DT TSE QE+   +++  K   R+    K +   L+ +  +
Sbjct: 13707 ALEETVATTAKQPIVIKLEDTLTSEVQEMRDHLNNEIKELARMKTIMKMEKDQLKQAKSD 13766

Query: 887   LQ 882
             +Q
Sbjct: 13767 IQ 13768



 Score = 84.0 bits (206), Expect = 4e-13
 Identities = 144/703 (20%), Positives = 297/703 (42%), Gaps = 38/703 (5%)
 Frame = -3

Query: 3074  VVDREAHIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQ-H 2898
             +V+R A+++  +E+  A   E+  LE    +  E+ ++LK E+ +  E S++  +EK+  
Sbjct: 8178  LVERTANLE--VEESAATDIERLVLE--VVKIREMVRNLKGEMERRMEESKVEIDEKEIF 8233

Query: 2897  TIELQENFNALRQKNEDIC-LKIEANNNLLEQK--DNIIVELSHKLQENEEQRSALQNDM 2727
               E+Q     + Q  E++  LK E  N   ++   + +  EL  K QE E  R  LQ + 
Sbjct: 8234  KSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNLEKMKAELEEKQQEEESMREILQKEK 8293

Query: 2726  QSVEQMHAVSQTERE--ELNRQLVLLR---------DDVNHLKEALSMAVDDRAFMEKQL 2580
             + +EQ+      E+E  E++R+LV             DV   KE L +  ++    ++ L
Sbjct: 8294  EELEQLKKDINREKEDIEISRELVESEIYEGEVKGFTDVQKYKEELQIVTEELLTKKRNL 8353

Query: 2579  QDLENQKETVSKELALSVSREQKLASDLKALS---EKEESTKNQLLIQTEQNKQLELEIE 2409
             + L +  + + + L     +  K  ++L+ ++   +K E    +   + E+N  +  EIE
Sbjct: 8354  EQLNSDVQHLMQTLEEVDIQYIKKKAELEHITSEIQKREQILEKQKKKLEENGWIIEEIE 8413

Query: 2408  KLYGSLQMKQMENTLLKDGNEKIYDLCKL-----------LATKSREVQGQQEGI----- 2277
              +  +L+   ME    ++  EK  +  +            L  +  EV+  ++ +     
Sbjct: 8414  MMKVTLESINMEILQKREDMEKEKENLRREKQETELFRGELQRQRDEVESSRQALIMEKD 8473

Query: 2276  ---LKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVL 2106
                LK D    +  A  ++  +   +M+    +  AK++  L     M+  +  +K E+ 
Sbjct: 8474  QFKLKIDHQRNEMSAAFEKEHKRLENMENDLENQRAKLAESLNDAAKMEQKLQQMKNELN 8533

Query: 2105  GNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQ 1926
                  +    QMV+    +++  K E+  + +       +LQ + +    +L +   ++ 
Sbjct: 8534  KEKEQVEEMKQMVKTERVKIEQEKEEMRKQTQEIEDGHEKLQKKTEIADKLLQDANSESD 8593

Query: 1925  TLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSL-KAELHLQAQKAFQIQEERNVVE 1749
              L+D S +        + +  ++   N  +E++ RSL +    LQ  K  +++ +R+  E
Sbjct: 8594  RLKDLSMK-------LQMQRQDIEKTNTEMETKKRSLDRMSRELQDDK-IRLKNDRDAYE 8645

Query: 1748  SEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRIL 1569
              +   L  + E L   ++E++DLE   L+  E       E+A  DIE+   A E +M++ 
Sbjct: 8646  KDMTHLELKREEL---VRETEDLERKILQQRE-----QDEMAKRDIENQTEALE-VMKV- 8695

Query: 1568  DELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEE 1389
              +++  RNE AK            E +NV   R + + +  +          R F  +++
Sbjct: 8696  -DILKKRNEFAK------------EMENVHSERQKLLLLQGALQSQESELENRVFMEEQK 8742

Query: 1388  DSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXX 1209
                       +C +         + AEM ET + E  +    +EE+Q+    +       
Sbjct: 8743  HLKQAKAETEECRK---------QLAEMSETVTTEQNEYRKLIEELQREKEQL------- 8786

Query: 1208  XXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEIN 1080
                  ++   KK+   ++S ++ +L    S +H + +   E N
Sbjct: 8787  EISKNQIEQEKKDLQNMKSNLERQL---ESLRHEKANVEDEKN 8826



 Score = 83.6 bits (205), Expect = 5e-13
 Identities = 96/484 (19%), Positives = 222/484 (45%), Gaps = 27/484 (5%)
 Frame = -3

Query: 3053  IKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENF 2874
             IK L++    +  E  E + +     E+  +L+ +  +L+E+    E EK H +E ++  
Sbjct: 13439 IKTLVQTEKQMAIEDTEKKTEV----ELQMNLQKQKNELEELRNTIEAEK-HQVENRKIM 13493

Query: 2873  NALRQKN-EDICLKIEANNNLLEQKDNIIVELSHKL-----QENEEQRSALQNDMQSVEQ 2712
                +QK  EDI   I++  ++LE++ + + +LSH L     +E EE    L+ +   +E 
Sbjct: 13494 LDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIEN 13553

Query: 2711  MHAVSQTEREELNRQLVLLRDDVNHLKEAL------SMAVDDRAFMEKQLQDLENQKETV 2550
                + ++E++ + R+    R ++  LKE +      ++   D+  ++K+ + LE +K   
Sbjct: 13554 CKKIIESEKQSIERE----RAELKRLKEEVEVQHERTLLQQDKNMIQKEKEHLEGEKART 13609

Query: 2549  SKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMEN 2370
             ++E+       ++ +S+L  L+++ E+ + +               E+L+G  +  ++E+
Sbjct: 13610 TEEIHNLKEEIKRKSSELDMLNKEIEAKRQE---------------EELHGLPEEIEIED 13654

Query: 2369  TLLKDGNEKIYDLCKLLATKSREVQGQQEGILK---QDINIE---DELARTKEVGRSATD 2208
              L K+      D+ +    K ++    Q+  LK   +D   +   DE+ +T E  + A +
Sbjct: 13655 HLKKED-----DVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRALE 13709

Query: 2207  MKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSE 2028
                  +   AK   ++++   +  +V  +++ +   I  L     ++++  +Q++  KS+
Sbjct: 13710 ETVATT---AKQPIVIKLEDTLTSEVQEMRDHLNNEIKELARMKTIMKMEKDQLKQAKSD 13766

Query: 2027  LFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWN---------AK 1875
             +  + E   + +     E    +  L++L    + L +   +  KE+ N         A+
Sbjct: 13767 IQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLDKKNKEIENNTETFLKKIAQ 13826

Query: 1874  ARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELK 1695
                  V+ K      +N  L+ +   Q ++  +IQ + +V  +E  + + +V   K+EL+
Sbjct: 13827 LETTIVLMKKDKENIENELLQLK---QIEQEREIQRKADVTSTEKEMYTEKV-TYKTELE 13882

Query: 1694  ESKD 1683
             +SK+
Sbjct: 13883 DSKE 13886



 Score = 81.3 bits (199), Expect = 3e-12
 Identities = 129/644 (20%), Positives = 276/644 (42%), Gaps = 39/644 (6%)
 Frame = -3

Query: 3050 KQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKE-VSRLYEEEKQHTIELQENF 2874
            + + +  N ++KEK EL  D     E  Q+ KDE+ + +E + +L +E ++  ++  E  
Sbjct: 6957 RDMDDTTNIMMKEKAELARDL----ENLQNEKDELQKSRENIQKLMKELQEERLKTSEAL 7012

Query: 2873 NALRQK-NEDICLK----------IEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDM 2727
            N  RQ+  E+I LK          I+     L     II +    LQ+ ++ R   Q+D 
Sbjct: 7013 NKERQQFTEEIKLKNDSLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDVRR--QSDE 7070

Query: 2726 QSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVS 2547
              + +  A  Q ERE L++  V +      L+      ++    +E Q  D EN K+  +
Sbjct: 7071 SDIAR--ANLQRERESLDQLSVEILKQKQDLERERDELLEQWRLVETQKMDNENVKQLKT 7128

Query: 2546 KELALSVSRE---QKLASDLKALSEKE---ESTKNQLLIQTEQNKQLELEIEKLYGSLQM 2385
            + L    S E   ++L  D   + E +        +L +Q +  +    ++E++ G LQM
Sbjct: 7129 ELLDEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNLQKQGIQDERAQLERMKGELQM 7188

Query: 2384 KQMENTLLKDGNEKIYDLCKLLATKSR---------EVQGQQEGILKQDINIEDELARTK 2232
            K   + + +   E +Y+  K    KS          E   + + + K+    ++ L + K
Sbjct: 7189 K--ADDIERKMQEILYEKQKYAERKSENYKIQTYLDEANAEVQKLNKELERYDENLEKCK 7246

Query: 2231 -EVGRSATDMKKVNSDAGAKV---SGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQ 2064
             E+ ++  + ++V    GAK+     I + L   +D +  ++  +     ++  D   ++
Sbjct: 7247 LELDKARAETERVKQ--GAKIPETQQIEQSLQKERDYIEDIRRNLFKKEEAIEKDKAEIR 7304

Query: 2063 VALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELW 1884
            +  +++   ++++  + E   ++ +  + E   IQ    +L+R  + L+D+ Q+  +E+ 
Sbjct: 7305 LRHQELDLIQAKVVKQKEEMVKQKIESERE---IQQEKKKLQRSEEELEDKMQKIKREMI 7361

Query: 1883 NAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKS 1704
              K   +    K  +++++ R +       A+K  ++++ +  VES    L  +   L +
Sbjct: 7362 ELKLLQDETDGKRKDVDNKMRQV-------ARKRDELEKMKADVESASKKLEVDRVMLNT 7414

Query: 1703 ELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDEL--------ICLR 1548
            E  E + ++    R  E  +  H E  + D+        ++ R++ E             
Sbjct: 7415 ERDELERIKTESQRATE-HMQSHAEERAGDLGEKEPVNTRIQRLIQEAEKASKMAWSTKH 7473

Query: 1547 NENAKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDL 1368
                +++ E   E    ER+++S +  + M + I  +    R  + E Q   ++ S ++ 
Sbjct: 7474 EPEMRMQREVSVEEESVERQDMS-ANMQRMILEIEHARETLRGMKDEVQAARKERSELEN 7532

Query: 1367 LKNKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEMQQTLS 1236
            +K     LEF   K     + +E ++ E Q+   ++E  +  LS
Sbjct: 7533 MK-----LEFLTMK-KNMEKTYEQQNDEIQKEKQQIESSKMLLS 7570



 Score = 77.0 bits (188), Expect = 5e-11
 Identities = 114/569 (20%), Positives = 237/569 (41%), Gaps = 58/569 (10%)
 Frame = -3

Query: 3209  LEDYYALQKKAGELQTKVHIREEESCK----HLTEALENHIYGSL-LESCVVDREAHIKQ 3045
             LED  + +KK  +  + + + + +S K       + LE  +   L L       +  +  
Sbjct: 14222 LED--SKEKKKPDRDSSLKLTDADSAKTDGEREAQTLETKVQDVLQLTDYTTQDQEELHD 14279

Query: 3044  LMEQMNALVKEKRELENDAQRGEEISQSLKDE----VFQLKEVSRLYEEEKQHTIELQEN 2877
              ME    ++ E  E + D Q+ +E  +S ++E    +  L+      E+ +   + L + 
Sbjct: 14280 EMENKMKIILELNEAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQE 14339

Query: 2876  FNALRQ-KNE----DICLKIEANNNLLEQKDNIIVE--------LSHKLQENEEQRSALQ 2736
              + L Q K E    +I ++I+  +   + + ++ ++          H  +++EE+ SA +
Sbjct: 14340 IDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQIQQGQEATETTGHITKKSEEEISAKK 14399

Query: 2735  NDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKE 2556
                 +V ++     +E +E+   L    +DV  +K  + M  D    +E+   D++ Q E
Sbjct: 14400 TKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVARMKTIMKMEKDQ---LEQAKSDIQTQME 14456

Query: 2555  TVSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQM 2376
                + +  ++  + +    L  L+  +E   N L    ++NK++E   E     +   + 
Sbjct: 14457 EFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTL---DKKNKEIENNTETSLKKIAQLET 14513

Query: 2375  ENTLLKDGNEKI-YDLCKLLAT-KSREVQ------GQQEGILKQDINIEDELARTKEVGR 2220
                L+K   E I  +L +L  T + RE+Q        +     + +  + EL   KE  +
Sbjct: 14514 TIVLMKKDKENIENELLQLKQTEQEREIQRGTDDTSNEREKYDEKVTYKTELEDNKEKKK 14573

Query: 2219  SATDMKKVNSDA-GAKVSGILEM---------LLPMKDDVFSLKEE----------VLGN 2100
                D     +DA  AK  G  E          +L + DD    +EE          ++  
Sbjct: 14574 PDRDSSLKLTDADSAKTDGEREAQTLETKVQDVLQLTDDTTQDQEELHDEMENKMKIILE 14633

Query: 2099  INSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEV----DAIQHILIELKRK 1932
             +N  + D Q ++      ++ KS +    E R   + ++Q+EV      I+H L ++K +
Sbjct: 14634 LNEAKKDLQKLKEKCRSAEEEKSVIMESLERRRNSLEKVQSEVLTLTQEIEH-LAQIKTE 14692

Query: 1931  NQTLQDESQRNAKEL---WNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEER 1761
              Q ++ + QR  + +   W    ++     +       + + K+E  + A+K      ++
Sbjct: 14693 MQQIETKMQRQTRSVATQWETDVQIQQEGQEATETRG-HITKKSEEEISAKKT-----KQ 14746

Query: 1760  NVVESEHNVLSSEVENLKSEL-KESKDLE 1677
               V    + L+SEV+ ++  L KE +D+E
Sbjct: 14747 PTVTKLEDTLTSEVQEMRDSLNKEMEDVE 14775



 Score = 76.6 bits (187), Expect = 6e-11
 Identities = 187/939 (19%), Positives = 390/939 (41%), Gaps = 60/939 (6%)
 Frame = -3

Query: 3194  ALQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREAHIKQLMEQMNALVK 3015
             AL K+    + ++  RE+     + E LE     SL E    +R     Q   + +  + 
Sbjct: 7591  ALDKQKLLAENELLEREKADVIKIIENLE-----SLREEATRERATETAQATRRDSEELM 7645

Query: 3014  EKRELENDAQRGEEISQSLKDEVFQLK-EVSRLYEEEK---QHTIELQENFNALRQKNED 2847
             +K E    A   E+  ++ K+++ +LK ++ +L E +    Q   EL++    L+Q+ +D
Sbjct: 7646  QKME----ALSMEDFQEASKNQMVELKRQIDKLIELKADLLQQQTELKKTKADLKQQMDD 7701

Query: 2846  ICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQ 2667
               L+   +  L  +KD        +L E + Q+  L+  +Q +     + + + E L  +
Sbjct: 7702  --LEKTRSEILKHEKDTDSKTRELELIEIQRQKDDLETRIQKL----TLEKRDLEVLRSE 7755

Query: 2666  LVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKE---LALSVSREQKLASDL 2496
             +VL + D   L + +   +  R  MEK   D+ N  E +++E   L +  +  Q    D 
Sbjct: 7756  IVLEKKD---LDQKMKQVIRKRDEMEKIRSDIANATEEINRERQELEILRNNVQSARHDF 7812

Query: 2495  KALSEKEESTKNQLLIQTEQNKQLELEIEK-------LYGSLQMKQMENTLLKDGNEKIY 2337
             + L E+  + +++    T+  + L LE+ K       L G ++ ++ME + ++   ++I+
Sbjct: 7813  ELLLERTANLEDEESAATDIER-LVLEVVKIREMVRNLKGEME-RRMEKSKVEIDEKEIF 7870

Query: 2336  DLCKLLATKSREVQG--QQEGILKQDIN-IEDELARTKEVGRSATDMKKVNSDAGAKVSG 2166
                        E+Q   Q  G +++++  + +E+ +T+   R    M+   ++   +   
Sbjct: 7871  ---------KSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAELAEKQQEQES 7921

Query: 2165  ILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVAL---------------EQMQDTKS 2031
             + EML   ++++  LK+E+      +    ++V+  +               E++Q    
Sbjct: 7922  MREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTE 7981

Query: 2030  ELFAEAEIRAQ-----EVLRLQAEVDAIQH---------ILIELKRKNQTLQ---DESQR 1902
             EL  +     Q     + LR   E   IQH         I  ELK+  Q L+   DE + 
Sbjct: 7982  ELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFELKKGEQLLEKQKDELKE 8041

Query: 1901  NAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSE 1722
             N   +   K + +++   N+ +  +N  +  E     Q+  ++   R+ ++ +   L + 
Sbjct: 8042  NGWIVEEIKNKKDSLEKINMEILRKNEDMDKEKGKLRQEKQEMDLFRSELQRQREDLETS 8101

Query: 1721  VENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNE 1542
             ++ L  E +E + L        EI+L    E   LD +      ++++R  DE+  +R +
Sbjct: 8102  IQKLTHEKREMEVLRS------EIVL----EKKDLDQKM-----KQVIRKRDEMEKIRFD 8146

Query: 1541  NAKLKNEALYEYHDYE--RKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGVDL 1368
              A  + E   E  + E  R NV  +R +             R  +R    + E+S+  D+
Sbjct: 8147  IANARVEIDGERQELEILRDNVQSARQDF-----------ERLVERTANLEVEESAATDI 8195

Query: 1367  LKNKCTRLEFQVQKLSE-----KAEMFETKSREAQQMANKLE----EMQQTLSDMXXXXX 1215
                   RL  +V K+ E     K EM E +  E++   ++ E    E+Q+ + D+     
Sbjct: 8196  -----ERLVLEVVKIREMVRNLKGEM-ERRMEESKVEIDEKEIFKSEIQRLIQDIGQIRE 8249

Query: 1214  XXXXXXIRVRSLKKENTRLRSEMKGELTPSRSFKHREGSFIKEINIGDEDDTPLIQXXXX 1035
                     + + K++ + L  +MK EL      K +E   ++EI   ++++   ++    
Sbjct: 8250  NLGGLKTEIENTKRDKSNL-EKMKAELEE----KQQEEESMREILQKEKEELEQLKKDI- 8303

Query: 1034  XXXXXXXKIDTRTSETQEIDTLMDDNRKYWNRVSHFTKQTQSLQNSVQELQQXXXXXXXX 855
                        R  E  EI   + ++  Y   V  FT     +Q   +ELQ         
Sbjct: 8304  ----------NREKEDIEISRELVESEIYEGEVKGFT----DVQKYKEELQIVTE----- 8344

Query: 854   XXXXXXKWGGIDMNSIEKQLKELNIHVMQLVEHNTRLKKDVKFGFAWANSMHDLNGQEQK 675
                        ++ + ++ L++LN  V  L++  T  + D+++    A   H  +  +++
Sbjct: 8345  -----------ELLTKKRNLEQLNSDVQHLMQ--TLEEVDIQYIKKKAELEHITSEIQKR 8391

Query: 674   LKVDEEVPILCHQNSKIAERLDINTDKARALDMEVQRIR 558
              ++ E+      +N  I E +++      +++ME+ + R
Sbjct: 8392  EQILEKQKKKLEENGWIIEEIEMMKVTLESINMEILQKR 8430



 Score = 75.5 bits (184), Expect = 1e-10
 Identities = 138/668 (20%), Positives = 278/668 (41%), Gaps = 37/668 (5%)
 Frame = -3

Query: 3146  EEESCKHLTEALENHIYGSLLESCV--VDREAHIKQLMEQMNALVKEKRELENDAQRGEE 2973
             +EE  + +   +E      +LES V  +  E  I +  +  N L++E  +LE   +R + 
Sbjct: 13180 KEEELRSMRADIERQ--AKILESDVQLLQTEKEILEKSKTENDLLRE--DLEKQRKRNDL 13235

Query: 2972  ISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNI 2793
               Q L+ E   L+++     +EK     LQ   N +  K  ++  K    +   ++ D++
Sbjct: 13236 TLQELRKEKMALEQMITDITKEKDAVASLQ---NEVSLKQHELKNKETELDEQRKEMDDL 13292

Query: 2792  IVELSHKLQENEEQRSA----------LQNDMQSVEQMHAVSQTEREELNRQLVLLRDDV 2643
              ++L  +     +Q+            ++ND++S   M  +   ER +L   +    D  
Sbjct: 13293 RMQLEMRQNSTNKQQQEVDVFIVENMKMRNDLES---MKTLLDEERRQLQDNIKTFEDQK 13349

Query: 2642  NHLKEALSMAVDDRAFMEKQLQDLENQKETVSKEL-ALSVSREQ--KLASDLKALSEKEE 2472
             N L  + + AV     +EK   D++ +KE V KE   + V  ++  K   +L++L+ + E
Sbjct: 13350 NVLHPSKTDAVQQTDELEKFTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIE 13409

Query: 2471  STKNQLLIQTEQNKQLE-LEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQ 2295
               K ++  +  Q + LE L  + L G+  +K +  T  +   E           K  EV+
Sbjct: 13410 MFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQTEKQMAIED--------TEKKTEVE 13461

Query: 2294  GQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKE 2115
              Q    L++  N  +EL  T E  +   + +K+  D   K    +  ++  + DV   ++
Sbjct: 13462 LQMN--LQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEK 13519

Query: 2114  EVLGNINSLRND-AQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELK 1938
               L  ++ + N+  Q  Q  LE++                    L+ E D I++    ++
Sbjct: 13520 SELNKLSHVLNEKVQREQEELERL--------------------LEKERDDIENCKKIIE 13559

Query: 1937  RKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERN 1758
              + Q++    +R   EL   K  +     + +  + +N   K + HL+ +KA   +E  N
Sbjct: 13560 SEKQSI----ERERAELKRLKEEVEVQHERTLLQQDKNMIQKEKEHLEGEKARTTEEIHN 13615

Query: 1757  VVE------SEHNVLSSEVENLKSE-----LKESKDLEGYFLRLFEILLGQHVEVASLDI 1611
             + E      SE ++L+ E+E  + E     L E  ++E +  +  ++L  + ++    D 
Sbjct: 13616 LKEEIKRKSSELDMLNKEIEAKRQEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDA 13675

Query: 1610  E-------SCRFAEEKLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSV 1452
                     + R AE +    LDE+     +  + +  AL E        V+ +  + + +
Sbjct: 13676 SQKFQLKTTSRDAETQTS--LDEI----TKTDERRQRALEE-------TVATTAKQPIVI 13722

Query: 1451  LISKSLGNGRANQREFQNKE--EDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQ 1278
              +  +L +     R+  N E  E +    ++K +  +L+     +  + E FE    EA 
Sbjct: 13723 KLEDTLTSEVQEMRDHLNNEIKELARMKTIMKMEKDQLKQAKSDIQTQMEEFERNMEEAM 13782

Query: 1277  QMANKLEE 1254
             +  ++ EE
Sbjct: 13783 EEKSRNEE 13790



 Score = 75.1 bits (183), Expect = 2e-10
 Identities = 109/585 (18%), Positives = 249/585 (42%), Gaps = 36/585 (6%)
 Frame = -3

Query: 2789 VELSHKLQENEEQ-RSALQNDMQSVE-QMHAVSQ--TEREELNRQLVLLRDDVNHLKEAL 2622
            +E   KL E  +Q R+ + N  Q ++ Q   +++  TE+ +L R +  ++ +++H++E +
Sbjct: 145  IEQIEKLWEGTKQERTEIDNMKQKIQRQQDEITRMTTEKGQLERTITHMKAEIDHIRERM 204

Query: 2621 SMAVD----DRAFMEKQLQDLENQKETVSKELALSVSREQKL-------ASDLKALSEKE 2475
                +    +R  +E+   DL+ ++ ++ ++    ++  Q L           + L    
Sbjct: 205  DRNKEEVNRERERVEQMRSDLQAEQSSLQQKRDEIMTERQNLEMIRYETLRQQEELESNR 264

Query: 2474 ESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQ 2295
            ESTK+++    +    ++++I ++   +   Q    L++    +I D    L  K  +++
Sbjct: 265  ESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLMEQMKAEIEDEKNELEKKKEDIK 324

Query: 2294 GQQEGILKQDINIEDELARTK-EVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLK 2118
             Q++    Q   I+ +L + K E+ +   + +K   +  A +    E L  ++D++  ++
Sbjct: 325  RQRD----QFEQIKLDLQQVKMEMEQRWHETEKEGLEQRAVIQREKEQLKYLQDEIQRVR 380

Query: 2117 EEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELK 1938
            EEV  N    R  ++     + Q++    E     E +  ++LR + +++ ++H   E++
Sbjct: 381  EEVERN----REFSKQEHARISQLRAQALEENNLIENKWHDILRKEKDLEEMKH---EIE 433

Query: 1937 RKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERN 1758
            R  + L    +   KE    +    ++ S  I++E +   +K E         ++Q +++
Sbjct: 434  RGREELVMNGELVKKEWEKIEQAKVDIQSHMISMEGRVDEIKRETERLKHIKTEMQRDKD 493

Query: 1757 VVESE---------------HNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQHVEVA 1623
             +E +               + +++ E+E+     +E  +LE     +  +   +  ++ 
Sbjct: 494  ALEKQKDDTRKAKEEAERKRYEIVTEELEHRARLQRERDELENIRAEMQRVNDVEKAKIL 553

Query: 1622 SLDIESCRFAEE-KLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRAEAMSVLI 1446
                ES R  EE +  R   EL+     NA++K E        ER N    R E M   +
Sbjct: 554  KEKEESIRIREEARQERETTELV-----NAEIKAEK-------ERLN---QRQEEM---L 595

Query: 1445 SKSLGNGRANQREFQNKEEDSSGVDLLKNKCTRLEFQVQKLSEKAEMFETKSREAQQMAN 1266
             +     R      + KEE  +  D+   +  ++E    ++  + E  E K  E Q+   
Sbjct: 596  RERQEIERIKHETLRAKEEIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKE 655

Query: 1265 KLE----EMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMK 1143
            ++E    E+++   D+            +   L+ E  R++ EM+
Sbjct: 656  QMEEAKVELEEEREDLERKRDLVSREIEQAEFLRNEILRVKEEME 700



 Score = 73.9 bits (180), Expect = 4e-10
 Identities = 112/637 (17%), Positives = 274/637 (43%), Gaps = 37/637 (5%)
 Frame = -3

Query: 3050 KQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFN 2871
            K + ++M+ L + + EL+ +A + E+  Q +++E  +L +++   +EE++    L E  N
Sbjct: 6528 KLIEDEMDKLKQMRAELQKEADQIEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEIN 6587

Query: 2870 A--LRQKNEDICLKIEANN--NLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHA 2703
               + Q+ +    ++E  +   +  + D    EL+ + ++N++  + +Q + +++E+M A
Sbjct: 6588 IQKVNQQKQATAFQMEKTDFERIKTEIDQANKELADQQEKNKKTITEMQKERETLEEMRA 6647

Query: 2702 -----------------VSQTEREELNRQLVLLRDDVNHLKEALSMAV-------DDRAF 2595
                               ++E  +L   ++  + +++ LK  + M +        D   
Sbjct: 6648 NISKQVETITNENKSLSSRESELAKLQEDILQQQQEMDELKNTIMMEMCQLDQRQSDIDL 6707

Query: 2594 MEKQLQDLENQKET----VSKELALSVSREQKLASDLKALSEKEESTKNQLLIQTEQNKQ 2427
            ++K++ DL +  +T    V +E    +++ + + SD+ +L  ++E+ +   L   E+   
Sbjct: 6708 LQKEVDDLMDFTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLNEEKDL 6767

Query: 2426 LELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDE 2247
            +E E E L  +L     +   +K   E        L  +   ++ +++ + K  I+++ +
Sbjct: 6768 IEKERELLTKNLDHTDKDKMDMKRELEN-------LKVEKETIKNEKKELEKMKISLQRK 6820

Query: 2246 LARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLGNINSLRNDAQMV 2067
                KE      D + +  +  A+ +  L++     +  F   EE L      R      
Sbjct: 6821 AIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFI--EERLDQTEKKRRKTYYT 6878

Query: 2066 QVALEQ----MQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRN 1899
            +   ++    +Q TK E+  + E    E+ R + E++  +  L ++   N    +  ++ 
Sbjct: 6879 EDLFQEEKTDLQKTKEEINYDRE----EIYRQRTELNKEKETLKQMHTSNLKEIENIEKE 6934

Query: 1898 AKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEV 1719
             +++      L+ + ++   L+++ R +    ++  ++  ++  +   +++E + L    
Sbjct: 6935 KEKIQRTWNELDQIRAE---LQNKQRDMDDTTNIMMKEKAELARDLENLQNEKDELQKSR 6991

Query: 1718 ENLKSELKESKDLEGYFLRLFEILLGQHVEVASLDIESCRFAEEKLMRILDELICLRNEN 1539
            EN++  +KE   L+   L+  E L  +  +      E  +   + L  I  E+   R + 
Sbjct: 6992 ENIQKLMKE---LQEERLKTSEALNKERQQFT----EEIKLKNDSLDEIQAEID--RQKR 7042

Query: 1538 AKLKNEALYEYHDYERKNVSGSRAEAMSVLISKSLGNGRAN-QREFQNKEEDSSGVDLLK 1362
            A + ++ +      + +     R +      S      RAN QRE   +  D   V++LK
Sbjct: 7043 ALVTDKEIITKQMMDLQKTQDVRRQ------SDESDIARANLQRE--RESLDQLSVEILK 7094

Query: 1361 NKCTRLEFQVQKLSEKAEMFETKSREAQQMANKLEEM 1251
             K   LE +  +L E+  + ET+  + + +     E+
Sbjct: 7095 QK-QDLERERDELLEQWRLVETQKMDNENVKQLKTEL 7130



 Score = 73.2 bits (178), Expect = 7e-10
 Identities = 121/657 (18%), Positives = 273/657 (41%), Gaps = 38/657 (5%)
 Frame = -3

Query: 3086  LESCVVDREAHIKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEE 2907
             +E+  V  + +I QL   +  + K+K  +EN              E+ QLK+     E+E
Sbjct: 14154 IENITVTFKRNIAQLETTIAMMKKDKENIEN--------------ELLQLKQT----EQE 14195

Query: 2906  KQHTIELQENFNALRQKNEDICLKIEANNNLLEQKDNI-----IVELSHKLQENEEQRSA 2742
             ++      +  N     +E +  K E  ++  ++K +      + +      + E +   
Sbjct: 14196 REIQRGTDDTSNERENYDEKVTYKTELEDSKEKKKPDRDSSLKLTDADSAKTDGEREAQT 14255

Query: 2741  LQNDMQSVEQMHAVSQTEREEL-----NRQLVLL-----RDDVNHLKEALSMAVDDRAFM 2592
             L+  +Q V Q+   +  ++EEL     N+  ++L     + D+  LKE    A ++++ +
Sbjct: 14256 LETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEECRSAEEEKSVI 14315

Query: 2591  EKQLQDLENQKETVSKELALSVSRE----QKLASDLKALSEKEESTKNQLLIQTEQNKQL 2424
              + L+   N  E V  E+ LS+++E     ++ ++++ +  K +     +  Q E + Q+
Sbjct: 14316 MESLERRRNSLEKVQSEV-LSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQI 14374

Query: 2423  EL--EIEKLYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIED 2250
             +   E  +  G +  K  E    K   +    + KL  T + EVQ  ++ + K+     +
Sbjct: 14375 QQGQEATETTGHITKKSEEEISAKKTKQPT--VTKLEDTLTSEVQEMRDSLNKE----ME 14428

Query: 2249  ELARTKEVGRSATD-MKKVNSDAGAKVSGILEMLLPMKDDVFSLKEEVLG---NINSLRN 2082
             ++AR K + +   D +++  SD   ++      +    ++    +E++L    +   L N
Sbjct: 14429 DVARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSN 14488

Query: 2081  DAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQR 1902
                     +E   +T  +  A+ E     ++ ++ + + I++ L++LK+  Q  + E QR
Sbjct: 14489 TLDKKNKEIENNTETSLKKIAQLETT---IVLMKKDKENIENELLQLKQTEQ--EREIQR 14543

Query: 1901  NAKELWNAKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSE 1722
                +  N + + +  ++    LE      K +    + K       +   E E   L ++
Sbjct: 14544 GTDDTSNEREKYDEKVTYKTELEDNKEKKKPDRD-SSLKLTDADSAKTDGEREAQTLETK 14602

Query: 1721  VENL----KSELKESKDLEGYFLRLFEILLGQHVEVASLDI----ESCRFAEEKLMRILD 1566
             V+++        ++ ++L        +I+L   +  A  D+    E CR AEE+   I++
Sbjct: 14603 VQDVLQLTDDTTQDQEELHDEMENKMKIIL--ELNEAKKDLQKLKEKCRSAEEEKSVIME 14660

Query: 1565  ELICLRNENAKLKNEAL---YEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNK 1395
              L   RN   K+++E L    E     +      + E      ++S+        + Q +
Sbjct: 14661 SLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIETKMQRQTRSVATQWETDVQIQQE 14720

Query: 1394  EEDSSGVDLLKNKCTRLEFQVQKLSEK--AEMFETKSREAQQMANKLEEMQQTLSDM 1230
              ++++       K +  E   +K  +    ++ +T + E Q+M + L +  + +  M
Sbjct: 14721 GQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVERM 14777



 Score = 72.8 bits (177), Expect = 9e-10
 Identities = 126/650 (19%), Positives = 272/650 (41%), Gaps = 43/650 (6%)
 Frame = -3

Query: 3050  KQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFN 2871
             K++       +K+  +LE      ++  +++++E+ QLK++    E+E+    E+Q   +
Sbjct: 13811 KEIENNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQI----EQER----EIQRKAD 13862

Query: 2870  ALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQ---------ENEEQRSALQNDMQSV 2718
                 + E    K+     L + K+ I  +    L+         + E +   L+  +Q V
Sbjct: 13863 VTSTEKEMYTEKVTYKTELEDSKEKIKPDRDSTLELTDTDSAKTDGEREAQTLETKVQDV 13922

Query: 2717  EQMHAVSQTEREEL-----NRQLVLL-----RDDVNHLKEALSMAVDDRAFMEKQLQDLE 2568
              Q+   +  ++EEL     N+  ++L     + D+  LKE    A ++++ + + L+   
Sbjct: 13923 LQLTDDTTQDQEELHDEMENKMKIILELNKAKKDLQKLKEECRSAEEEKSVIMESLERRR 13982

Query: 2567  NQKETVSKELALSVSRE----QKLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEK-- 2406
             N  E V  E+ LS+++E     ++ ++++ +  K +     +  Q E + Q++ E ++  
Sbjct: 13983 NSLEKVQSEV-LSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQIQQEGQEPI 14041

Query: 2405  -LYGSLQMKQMENTLLKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKE 2229
                G +  K  E    K   + I  + KL  T + EVQ  +      D+ IED +AR K 
Sbjct: 14042 ETTGHITKKSEEEISAKKTKQPI--VTKLEDTLTSEVQEMR------DMEIED-VARMKT 14092

Query: 2228  VGRSATD-MKKVNSDAGAKVSGI---LEMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQV 2061
             + +   D +++  SD   ++      +E  L  K        ++L + + L N       
Sbjct: 14093 MMKMEKDQLEQAKSDIQRQMEEFERNMEETLKEKSRNEETLLQLLHDKDDLSNTLDEKSK 14152

Query: 2060  ALEQMQDTKSELFAEAEIRAQEVLRLQAEVDAIQHILIELKRKNQTLQDESQRNAKELWN 1881
              +E +  T     A+ E     +  ++ + + I++ L++LK+  Q  + E QR   +  N
Sbjct: 14153 EIENITVTFKRNIAQLETT---IAMMKKDKENIENELLQLKQTEQ--EREIQRGTDDTSN 14207

Query: 1880  AKARLNNVMSKNINLESQNRSLKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKS- 1704
              +   +  ++    LE      K +    + K       +   E E   L ++V+++   
Sbjct: 14208 ERENYDEKVTYKTELEDSKEKKKPDRD-SSLKLTDADSAKTDGEREAQTLETKVQDVLQL 14266

Query: 1703  ---ELKESKDLEGYFLRLFEILLGQHVEVASLDI----ESCRFAEEKLMRILDELICLRN 1545
                  ++ ++L        +I+L   +  A  D+    E CR AEE+   I++ L   RN
Sbjct: 14267 TDYTTQDQEELHDEMENKMKIIL--ELNEAKKDLQKLKEECRSAEEEKSVIMESLERRRN 14324

Query: 1544  ENAKLKNEAL---YEYHDYERKNVSGSRAEAMSVLISKSLGNGRANQREFQNKEEDSSGV 1374
                K+++E L    E     +      + E    + ++S+        + Q  +E +   
Sbjct: 14325 SLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQIQQGQEATETT 14384

Query: 1373  DLLKNKCTRLEFQVQKLSEK--AEMFETKSREAQQMANKLEEMQQTLSDM 1230
               +  K +  E   +K  +    ++ +T + E Q+M + L +  + ++ M
Sbjct: 14385 GHITKK-SEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVARM 14433



 Score = 70.9 bits (172), Expect = 3e-09
 Identities = 152/779 (19%), Positives = 314/779 (40%), Gaps = 85/779 (10%)
 Frame = -3

Query: 3218  QKILEDYYA-LQKKAGELQTKVHIREEESCKHLTEALENHIYGSLLESCVVDREA-HIKQ 3045
             +K LE + A ++++A E++T    + E+  K      E H+ G  ++    + E   I +
Sbjct: 12012 KKDLEMFKAEIKREASEVKTLKEQQLEKDTKAFEALKEEHLPGQFVQQKGGEFERIQIDE 12071

Query: 3044  LMEQMNALVKEKRELENDAQRGEEISQSLKD----------------------EVFQLKE 2931
             +   ++ + KEK+ELE + Q  E   ++L +                      ++  + +
Sbjct: 12072 VKRILSEIHKEKKELERNKQILEHQREALLEIKSKQPSERLDVILVSSATQTSDLEDIPD 12131

Query: 2930  VSRLYEEE-KQHTIELQENFNALRQKNEDIC-LKIEANNNLLEQKDNII-----VELSHK 2772
             VS    E  ++HT  ++E   ++ ++  +I  LK + +  L   +++       V   +K
Sbjct: 12132 VSASQGETVEKHTDIIKEYTTSIPKEEYEIDKLKQQGDKKLKSTREDTKMADTEVTTQYK 12191

Query: 2771  LQENEEQRSALQNDMQSVEQMHAVSQTEREELNRQLVLLRDDVNHLKEALSMAVDDRAFM 2592
                +      L++     + +  V  TER EL    + L+ +   +++       ++  +
Sbjct: 12192 YIPDPSIMMKLESGKDETDGLTEVHTTERRELEITKLALQSEQQEIEKIRQDIDREKNDL 12251

Query: 2591  EKQLQDLENQ-------KETVSKELALSVSREQKLASDLKALSEKEESTKNQL------- 2454
             EK   DLE Q       K+ +  E A      + +  + K+  E+ ES + QL       
Sbjct: 12252 EKYRSDLEKQYEEMEICKQNIENERAELEIDLENIIIETKSKQERLESIEVQLQEKNVQM 12311

Query: 2453  -LIQTEQNK-QLELEIEKLYGSLQMKQMENTLLKDGNEKIYDLCK---LLATKSREVQGQ 2289
               I  E NK Q EL+  K     + +QM +T   + +E I  L K   ++     E+Q Q
Sbjct: 12312 GTILDELNKRQEELDAIKAKTQREKEQMGHTEELEKDELIAILQKREEIVKRHMEEIQNQ 12371

Query: 2288  QEGILK---QDINIEDELARTKEVGRSATDMKKVNSDAGAKVSGILEMLLPMKDDVFSL- 2121
             +E + K   Q  N++ EL +    G+   +M ++  ++       + + L  + + F L 
Sbjct: 12372 REELQKEKDQFGNMQAELQK----GQLEMEMHQLMLNSERDELNGMRVNLEKQKEEFELM 12427

Query: 2120  --------KEEVLGNINSLRNDAQMVQVALEQMQDTKSELFAEAEIRAQEVLRLQAEVDA 1965
                      E +L +I   +   + +   L + Q+    + +E   R +++ +++ E+  
Sbjct: 12428 QQNLESRRPESLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKIKQIEGEIKT 12487

Query: 1964  IQ---HILIELKRKNQTLQ--------DESQRNAKELWNAKARLNNVMSKNINLESQNRS 1818
              Q     L ELK+K    Q         E Q   +EL   K  ++    +   L  Q   
Sbjct: 12488 KQIEMACLEELKQKELDEQKNMRECENQELQMRREELAKMKTEIDIERDEIQKLRKQYEK 12547

Query: 1817  LKAELHLQAQKAFQIQEERNVVESEHNVLSSEVENLKSELKESKDLEGYFLRLFEILLGQ 1638
              K EL        + + E+   E +H+ +   +++LK E +E                  
Sbjct: 12548 EKCELEQIKPDLQKREPEKIDAEVQHDEIHGGIDSLKEEREE------------------ 12589

Query: 1637  HVEVASLDIESCRFAEEKLMRILD-ELICLRNENAKLKNEALYEYHDYERKNVSGSRAEA 1461
              +E    D+++     E +  I+  E   L  + A+++  A+    +   KN+     + 
Sbjct: 12590 -IEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKI 12648

Query: 1460  MSVL-ISKSLGN--GRANQREFQNKEEDSSGVDLLKNKCTRL--------EFQVQKLSEK 1314
              ++L ++K   N   + N+   + K E  +   +L+ + T L        EF + K+ E+
Sbjct: 12649 EAILKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKMEER 12708

Query: 1313  AEMFETKSREAQQMANKLEEMQQTLSDMXXXXXXXXXXXIRVRSLKKENTRLRSEMKGE 1137
                 +T  R   +MA + E++++   ++             +     E T+ +SE++ E
Sbjct: 12709 EAERKTIERVMDEMAEEHEKIKKEREELVNMEEEIKKQRRVLEESMNEMTKKKSELQHE 12767



 Score = 67.8 bits (164), Expect = 3e-08
 Identities = 134/684 (19%), Positives = 297/684 (43%), Gaps = 87/684 (12%)
 Frame = -3

Query: 3023 LVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENFNALRQKNEDI 2844
            +++E+ ELE  ++ G+   + L++   +L+EV +  +  +Q   ++      + Q  EDI
Sbjct: 1425 IMREQDELELMSKMGQRQREELEE---RLEEVIKENDRVEQMREDVNNALKDIDQAKEDI 1481

Query: 2843 CLKIEANNNLLEQKDNIIVELSHKLQENE------------EQRSALQNDMQSVEQMHAV 2700
              + E       Q   +  + S   +  E            E  +++Q + Q +E    +
Sbjct: 1482 QRQREVIAQEKVQPAIVATKSSEYAKTEEPGAIKSYRASDLELSASIQKERQELEHYKEI 1541

Query: 2699 SQTEREELNRQLVLLRDDV----NHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELAL 2532
               E+ ELN+    +++DV    N  +E +    ++   M+ +   L+N +  +  E   
Sbjct: 1542 ILKEKHELNK----IKEDVKAVKNDAEERMIKLHEEEKEMKTKRVSLQNWERQLQTEKEK 1597

Query: 2531 SVSREQKLASDLKALSE-KEESTKNQLLIQTEQNK---QLELEIEKLYGSLQMKQMENTL 2364
            +      + ++ + L+E K++    +L +Q+E++K   +  LEI+++   +Q + ME+  
Sbjct: 1598 NQKGLDAIWNENQQLNERKQQLDIKELHLQSEKSKLEYKKPLEIKQVDAQVQTELMEDAS 1657

Query: 2363 LKDGNEKIYDLCKLLATKSREVQGQQEGILKQDINIEDELARTKEVGRSATDMKKVNSDA 2184
              D    I +L K    + + ++  ++ +L Q   +E ++A   E+ R    +++     
Sbjct: 1658 EYDMALSIEELDK----QRQFLEYFKQELLAQKCTMERQMAEI-ELSRDELSLREATLQT 1712

Query: 2183 GAKVSGILEMLLPM--------KDDVFSLKEEV-------LGNINSLRNDAQMVQVALEQ 2049
              + +  +E+ L +        KD++   K EV          I   R   +MV++ LE+
Sbjct: 1713 ATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGWVDLQTQIAESREKEEMVRIELEK 1772

Query: 2048 MQDTKSELFAEAEIRAQEV-----LRLQAE---VDAIQHILIELKRKNQTLQDESQRNAK 1893
             +D  + +  + E   Q +       L  E   ++A + ++ + KR  + ++ E QR + 
Sbjct: 1773 ARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQRKMMEDEKRALENMKYELQRESG 1832

Query: 1892 ELWNAKARLNNVMSKNINLESQNRSLK---AELHLQAQKAFQIQEER------------- 1761
             +  +K   +N+  +  N+E+    LK    EL  +     Q+Q ER             
Sbjct: 1833 YIERSK---HNMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERSREIKDLENLREL 1889

Query: 1760 -----NVVESEHNVL----------SSEVENLKSELKESKDLEGYFLRLFEILLGQHVEV 1626
                 N ++++ +VL            E+EN KS++K    +  Y L+  +  L +  + 
Sbjct: 1890 NELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIK----IREYDLQQMQTDLNRQ-QK 1944

Query: 1625 ASLDIESCRFAEE-KLMRILDELICLRNENAKLKNEALYEYHDYERKNVSGSRA------ 1467
               DI++  F E+ +L +  DE+     E  K   + + ++   E+ N+   RA      
Sbjct: 1945 EMQDIQNAVFMEKSELKKSQDEIA----EQLKQVGD-MMQFTQNEKDNLDRERAAIIEQK 1999

Query: 1466 ----EAMSVLISKSLGNGRANQREFQNKEE--DSSGVDLLKNKCTRLEFQVQKLSEKAEM 1305
                  M+ L+++ L + +  ++E  N++   +   + L+++     + ++    EK EM
Sbjct: 2000 LQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEM 2059

Query: 1304 FETKSREAQQMANKLEEMQQTLSD 1233
             + + +   +  +KLE + QTL++
Sbjct: 2060 -QLQRQSIAEEKDKLESVLQTLAE 2082



 Score = 61.2 bits (147), Expect = 3e-06
 Identities = 88/450 (19%), Positives = 187/450 (41%), Gaps = 4/450 (0%)
 Frame = -3

Query: 3053  IKQLMEQMNALVKEKRELENDAQRGEEISQSLKDEVFQLKEVSRLYEEEKQHTIELQENF 2874
             +++L E+  +  +EK  +    +R     + ++ EV  L +     E   Q   E+Q+  
Sbjct: 14641 LQKLKEKCRSAEEEKSVIMESLERRRNSLEKVQSEVLTLTQE---IEHLAQIKTEMQQIE 14697

Query: 2873  NALRQKNEDICLKIEANNNLLEQKDNIIVELSHKLQENEEQRSALQNDMQSVEQMHAVSQ 2694
               ++++   +  + E +  + ++         H  +++EE+ SA +    +V ++     
Sbjct: 14698 TKMQRQTRSVATQWETDVQIQQEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLT 14757

Query: 2693  TEREELNRQLVLLRDDVNHLKEALSMAVDDRAFMEKQLQDLENQKETVSKELALSVSREQ 2514
             +E +E+   L    +DV  +K  + M  D    +E+   DL+ Q E     +  ++  + 
Sbjct: 14758 SEVQEMRDSLNKEMEDVERMKTMMKMEKDQ---LEQAKSDLQRQMEDFGSNMEEAMKEKS 14814

Query: 2513  KLASDLKALSEKEESTKNQLLIQTEQNKQLELEIEKLYGSLQMKQMENTLLKDGNEKIYD 2334
             +    L  L+  ++   N L     +N ++E  IE      +M Q+E T+     +K   
Sbjct: 14815 RNEEKLLQLTHDKDVLSNTL---DAKNAEIENIIESFI--KKMAQLETTIAIMEKDKENI 14869

Query: 2333  LCKLLATKSREVQGQQEGILKQDINIEDELAR--TKEVGRSATDMKKVNSDAGAKVSGIL 2160
               +LL  K            K+D  +E E ++  T++V +  +   +   D         
Sbjct: 14870 ENELLQQKD-----------KEDKAVETEFSQEPTEDVKQRRSIETQTEEDQETDAIPQY 14918

Query: 2159  EMLLPMKDDVFSLKEEVLGNINSLRNDAQMVQVALEQMQDTKSEL-FAEAEI-RAQEVLR 1986
               +  MK  +  +KEE+   +  +R   +M ++    MQ  K EL   +AEI R  E L+
Sbjct: 14919 GEIEAMKRRILEMKEELKSKLQDIRR-KEMERLG---MQREKIELELQKAEIERYNEALQ 14974

Query: 1985  LQAEVDAIQHILIELKRKNQTLQDESQRNAKELWNAKARLNNVMSKNINLESQNRSLKAE 1806
              + E D ++  L+E +R+   L++       +L +++             E+  + L+  
Sbjct: 14975 RERETDRLK--LMEKEREILLLREYMMIEINQLRSSETE-----------ETSPQHLEMM 15021

Query: 1805  LHLQAQKAFQIQEERNVVESEHNVLSSEVE 1716
              H  +  A ++ + R V +     L  E++
Sbjct: 15022 EHFISDAAVRMNQFRRVTDRAVQTLILEID 15051