BLASTX nr result
ID: Ephedra26_contig00022577
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Ephedra26_contig00022577
(768 letters)
Database: ./nr
37,332,560 sequences; 13,225,080,153 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|XP_002994738.1| hypothetical protein SELMODRAFT_432639 [Sela... 139 1e-30
ref|XP_001785784.1| predicted protein [Physcomitrella patens] gi... 131 2e-28
ref|XP_001764918.1| predicted protein [Physcomitrella patens] gi... 129 8e-28
ref|XP_001752297.1| predicted protein [Physcomitrella patens] gi... 104 4e-20
ref|XP_001787135.1| predicted protein [Physcomitrella patens] gi... 102 2e-19
ref|XP_001783329.1| predicted protein [Physcomitrella patens] gi... 65 3e-08
ref|XP_002308464.2| hypothetical protein POPTR_0006s22730g [Popu... 61 5e-07
ref|XP_006291061.1| hypothetical protein CARUB_v10017176mg [Caps... 60 8e-07
ref|XP_002965922.1| hypothetical protein SELMODRAFT_407067 [Sela... 59 2e-06
ref|XP_002983162.1| hypothetical protein SELMODRAFT_179994 [Sela... 59 2e-06
gb|EMJ05530.1| hypothetical protein PRUPE_ppa005248mg [Prunus pe... 58 4e-06
ref|XP_001781819.1| predicted protein [Physcomitrella patens] gi... 57 5e-06
gb|AAK59422.1| unknown protein [Arabidopsis thaliana] 57 5e-06
ref|NP_566970.1| uncharacterized protein [Arabidopsis thaliana] ... 57 5e-06
emb|CAB89222.1| putative protein [Arabidopsis thaliana] 57 5e-06
gb|ESW17287.1| hypothetical protein PHAVU_007G226900g [Phaseolus... 57 7e-06
ref|XP_004494048.1| PREDICTED: uncharacterized protein LOC101495... 57 9e-06
>ref|XP_002994738.1| hypothetical protein SELMODRAFT_432639 [Selaginella moellendorffii]
gi|300136996|gb|EFJ04195.1| hypothetical protein
SELMODRAFT_432639 [Selaginella moellendorffii]
Length = 481
Score = 139 bits (349), Expect = 1e-30
Identities = 71/147 (48%), Positives = 96/147 (65%)
Frame = +2
Query: 11 KVKEEVSFWELAKTISAKTAKEMKKHKHFSELPVLAMLIAQVIKRPSLTPGMSKRSGLFT 190
+VKE V FW+LA+ IS+ T K + K +HFSEL VL ML++QVIK PS+TP S R+ LFT
Sbjct: 340 QVKEGVPFWDLARQISSSTEKNLAKSRHFSELSVLNMLLSQVIKHPSVTPSSSMRTALFT 399
Query: 191 CFLGEPAKREWQSKQAEMKGLNIAGTLGPLASMHGIGPCFSTCEYMSEGKEGPELCVHLT 370
F+ P K W +K L +AGT+GPLASMH +GPCFS E + +GPEL +
Sbjct: 400 VFVDGPTKCSW----GNVKNLKLAGTIGPLASMHYVGPCFSVAEAL---LDGPELSLTFV 452
Query: 371 FATPVYTRDFMHGFATSAIDLLLSECA 451
+ TP+Y+R + +S++DLL S A
Sbjct: 453 YTTPMYSRSQLQDLVSSSLDLLKSAVA 479
>ref|XP_001785784.1| predicted protein [Physcomitrella patens]
gi|162662574|gb|EDQ49410.1| predicted protein
[Physcomitrella patens]
Length = 482
Score = 131 bits (330), Expect = 2e-28
Identities = 68/145 (46%), Positives = 93/145 (64%)
Frame = +2
Query: 2 QGAKVKEEVSFWELAKTISAKTAKEMKKHKHFSELPVLAMLIAQVIKRPSLTPGMSKRSG 181
QG +VKE VSFW+LA+++SA TAKE+ K K FSE+PVL ML +QV+K P+LTP S R+
Sbjct: 338 QGQQVKEGVSFWDLARSVSASTAKELSKSKQFSEIPVLNMLFSQVLKHPNLTPQSSMRTA 397
Query: 182 LFTCFLGEPAKREWQSKQAEMKGLNIAGTLGPLASMHGIGPCFSTCEYMSEGKEGPELCV 361
LF+ F+ E + ++ E + L +A GP SMHG+GPCF+ E EG L +
Sbjct: 398 LFSLFVDEAPLQLYK----EYQRLQVAAVAGPFPSMHGVGPCFAVSEAFCEGN---NLSI 450
Query: 362 HLTFATPVYTRDFMHGFATSAIDLL 436
L + PVYTR M + SA++LL
Sbjct: 451 SLIYPQPVYTRSQMQAYGASAMELL 475
>ref|XP_001764918.1| predicted protein [Physcomitrella patens]
gi|162683954|gb|EDQ70360.1| predicted protein
[Physcomitrella patens]
Length = 476
Score = 129 bits (325), Expect = 8e-28
Identities = 64/145 (44%), Positives = 92/145 (63%)
Frame = +2
Query: 2 QGAKVKEEVSFWELAKTISAKTAKEMKKHKHFSELPVLAMLIAQVIKRPSLTPGMSKRSG 181
QG + KE SFW+LA+T+SA TAKE+ K KH SE+PV ML +QV+K P++TP S R+
Sbjct: 332 QGQQAKEGCSFWDLARTVSALTAKELSKSKHLSEIPVPNMLFSQVLKHPNVTPQSSMRTS 391
Query: 182 LFTCFLGEPAKREWQSKQAEMKGLNIAGTLGPLASMHGIGPCFSTCEYMSEGKEGPELCV 361
LF+ F+ E K +W+ Q L + GP SMHG+GPCF+ E + +EG +L +
Sbjct: 392 LFSLFVDEAPKLQWRGYQ----NLQVGVVAGPFPSMHGVGPCFAISETL---REGNDLSI 444
Query: 362 HLTFATPVYTRDFMHGFATSAIDLL 436
+A PV+TR M + +A++LL
Sbjct: 445 SFIYAQPVFTRSQMSAYCAAAVELL 469
>ref|XP_001752297.1| predicted protein [Physcomitrella patens]
gi|162696692|gb|EDQ83030.1| predicted protein
[Physcomitrella patens]
Length = 329
Score = 104 bits (259), Expect = 4e-20
Identities = 57/142 (40%), Positives = 82/142 (57%)
Frame = +2
Query: 11 KVKEEVSFWELAKTISAKTAKEMKKHKHFSELPVLAMLIAQVIKRPSLTPGMSKRSGLFT 190
K K++ SF ++S T KE+ K K FSE+PVL ML +QV+K P +TP S R+ LF+
Sbjct: 125 KKKDDFSF----TSVSTTTEKELAKSKQFSEIPVLNMLFSQVLKHPGVTPQSSLRTALFS 180
Query: 191 CFLGEPAKREWQSKQAEMKGLNIAGTLGPLASMHGIGPCFSTCEYMSEGKEGPELCVHLT 370
F+ E +W + L +A GP SMH IGPCF+ C+ M +G ++ + L
Sbjct: 181 LFVDETPFNQWTNTDK----LQVAAVCGPFPSMHRIGPCFAVCDTMLDGN---DISISLM 233
Query: 371 FATPVYTRDFMHGFATSAIDLL 436
+ T VY+R M FA S ++LL
Sbjct: 234 YPTQVYSRAQMKAFAASVMNLL 255
>ref|XP_001787135.1| predicted protein [Physcomitrella patens]
gi|162659616|gb|EDQ48051.1| predicted protein
[Physcomitrella patens]
Length = 129
Score = 102 bits (253), Expect = 2e-19
Identities = 53/128 (41%), Positives = 75/128 (58%)
Frame = +2
Query: 53 ISAKTAKEMKKHKHFSELPVLAMLIAQVIKRPSLTPGMSKRSGLFTCFLGEPAKREWQSK 232
+S T KE+ K K FSE+PVL ML +QV+K P +TP S R+ LF+ F+ E +W +
Sbjct: 1 VSTTTEKELAKSKQFSEIPVLNMLFSQVLKHPGVTPQSSLRTALFSLFVDETPFNQWTNT 60
Query: 233 QAEMKGLNIAGTLGPLASMHGIGPCFSTCEYMSEGKEGPELCVHLTFATPVYTRDFMHGF 412
L +A GP SMH IGPCF+ C+ M +G ++ + L + T VY+R M F
Sbjct: 61 DK----LQVAAVCGPFPSMHRIGPCFAVCDTMLDGN---DISISLMYPTQVYSRAQMKAF 113
Query: 413 ATSAIDLL 436
A S ++LL
Sbjct: 114 AASVMNLL 121
>ref|XP_001783329.1| predicted protein [Physcomitrella patens]
gi|162665181|gb|EDQ51874.1| predicted protein
[Physcomitrella patens]
Length = 509
Score = 65.1 bits (157), Expect = 3e-08
Identities = 44/142 (30%), Positives = 68/142 (47%)
Frame = +2
Query: 14 VKEEVSFWELAKTISAKTAKEMKKHKHFSELPVLAMLIAQVIKRPSLTPGMSKRSGLFTC 193
+ E+V FWELAK S M KHF+++ L L+ Q I RP+LTP S R+ L
Sbjct: 373 LNEKVEFWELAKRCSGSLDNAMNNRKHFTDMGDLNYLMYQAISRPNLTPSGSLRTSLLVT 432
Query: 194 FLGEPAKREWQSKQAEMKGLNIAGTLGPLASMHGIGPCFSTCEYMSEGKEGPELCVHLTF 373
F A L+I +G +S+HG+GP + + + +G EL F
Sbjct: 433 FRDSMTDELGDLATA----LDIEDFVG-CSSVHGVGPSLAIFDTICKG----ELHCANVF 483
Query: 374 ATPVYTRDFMHGFATSAIDLLL 439
TP+++R M + + + L+
Sbjct: 484 PTPLHSRQQMQAYVDTMMSYLV 505
>ref|XP_002308464.2| hypothetical protein POPTR_0006s22730g [Populus trichocarpa]
gi|550336883|gb|EEE91987.2| hypothetical protein
POPTR_0006s22730g [Populus trichocarpa]
Length = 175
Score = 60.8 bits (146), Expect = 5e-07
Identities = 42/146 (28%), Positives = 71/146 (48%)
Frame = +2
Query: 11 KVKEEVSFWELAKTISAKTAKEMKKHKHFSELPVLAMLIAQVIKRPSLTPGMSKRSGLFT 190
++K WE+AK I A ++HF ++ L L+ + I P LTP S R+ L +
Sbjct: 31 EMKGGEKLWEMAKKIYTAFANSKNCNRHFLDMADLNFLMCKAIDNPGLTPSSSLRTALLS 90
Query: 191 CFLGEPAKREWQSKQAEMKGLNIAGTLGPLASMHGIGPCFSTCEYMSEGKEGPELCVHLT 370
F EP K ++ Q E+ + G AS HGIGP + + + +G+ CV
Sbjct: 91 VF-EEPVKDDYGGLQEEVGVEDYMG----CASAHGIGPSIAIFDRVRDGRLD---CV-CV 141
Query: 371 FATPVYTRDFMHGFATSAIDLLLSEC 448
+ +P+++R+ M F + +L+ C
Sbjct: 142 YPSPLHSREQMQEFIDNMKSVLVEGC 167
>ref|XP_006291061.1| hypothetical protein CARUB_v10017176mg [Capsella rubella]
gi|482559768|gb|EOA23959.1| hypothetical protein
CARUB_v10017176mg [Capsella rubella]
Length = 469
Score = 60.1 bits (144), Expect = 8e-07
Identities = 39/139 (28%), Positives = 69/139 (49%)
Frame = +2
Query: 23 EVSFWELAKTISAKTAKEMKKHKHFSELPVLAMLIAQVIKRPSLTPGMSKRSGLFTCFLG 202
E + W+LAK +KHF+++ L L+ + I+ P+LTP S R+ + F
Sbjct: 332 EETLWDLAKRCYDSFTSAKNSNKHFTDMSDLNFLMCKAIENPNLTPSSSLRTAFISIF-E 390
Query: 203 EPAKREWQSKQAEMKGLNIAGTLGPLASMHGIGPCFSTCEYMSEGKEGPELCVHLTFATP 382
+P E S + E+ L + +G AS+HG+GP + + + +GK L + +P
Sbjct: 391 DPVIDE--SPEPELASLGVQDYIG-CASIHGVGPSVAVFDALRDGK----LDCAFVYPSP 443
Query: 383 VYTRDFMHGFATSAIDLLL 439
+++R+ M G +LL
Sbjct: 444 LHSREQMDGLIQHMKTILL 462
>ref|XP_002965922.1| hypothetical protein SELMODRAFT_407067 [Selaginella moellendorffii]
gi|300166736|gb|EFJ33342.1| hypothetical protein
SELMODRAFT_407067 [Selaginella moellendorffii]
Length = 454
Score = 58.9 bits (141), Expect = 2e-06
Identities = 35/146 (23%), Positives = 75/146 (51%), Gaps = 2/146 (1%)
Frame = +2
Query: 14 VKEEVSFWELAKTISAKTAKEMKKHKHFSELPVLAMLIAQVIKRPSLTPGMSKRSGLFTC 193
V ++ FW+L++ S + +K KHF+++ + L+ Q ++ P+LTP + R+ L
Sbjct: 316 VNQDTGFWDLSRRCSDSFSNAIKNRKHFTDMGDINYLMFQALQHPNLTPSGTLRTSLMVV 375
Query: 194 FLGEPAKREWQSKQAEMKGLNIAGTLGPLASMHGIGPCFSTCEYMSEGKEGPELCVH--L 367
F A +S++ L + +G AS+HG+GP + + + +G C+H +
Sbjct: 376 FQDVIAD---ESEEETKHTLGLEDYVG-CASVHGVGPSLALFDSIRDG------CLHCNV 425
Query: 368 TFATPVYTRDFMHGFATSAIDLLLSE 445
+ P+++R+ + +++L S+
Sbjct: 426 VYPAPLHSREQIRKVVDDMMEILKSQ 451
>ref|XP_002983162.1| hypothetical protein SELMODRAFT_179994 [Selaginella moellendorffii]
gi|300149315|gb|EFJ15971.1| hypothetical protein
SELMODRAFT_179994 [Selaginella moellendorffii]
Length = 454
Score = 58.9 bits (141), Expect = 2e-06
Identities = 35/146 (23%), Positives = 75/146 (51%), Gaps = 2/146 (1%)
Frame = +2
Query: 14 VKEEVSFWELAKTISAKTAKEMKKHKHFSELPVLAMLIAQVIKRPSLTPGMSKRSGLFTC 193
V ++ FW+L++ S + +K KHF+++ + L+ Q ++ P+LTP + R+ L
Sbjct: 316 VNQDTGFWDLSRRCSDSFSNAIKNRKHFTDMGDINYLMFQALQHPNLTPSGTLRTSLMVV 375
Query: 194 FLGEPAKREWQSKQAEMKGLNIAGTLGPLASMHGIGPCFSTCEYMSEGKEGPELCVH--L 367
F A +S++ L + +G AS+HG+GP + + + +G C+H +
Sbjct: 376 FQDVIAD---ESEEETKHTLGLEDYVG-CASVHGVGPSLALFDSIRDG------CLHCNV 425
Query: 368 TFATPVYTRDFMHGFATSAIDLLLSE 445
+ P+++R+ + +++L S+
Sbjct: 426 VYPAPLHSREQIRKVVDDMMEILKSQ 451
>gb|EMJ05530.1| hypothetical protein PRUPE_ppa005248mg [Prunus persica]
Length = 470
Score = 57.8 bits (138), Expect = 4e-06
Identities = 40/130 (30%), Positives = 65/130 (50%)
Frame = +2
Query: 14 VKEEVSFWELAKTISAKTAKEMKKHKHFSELPVLAMLIAQVIKRPSLTPGMSKRSGLFTC 193
+K + WELAK A KHF++L L+ ++ + I+ P+LTP S RS T
Sbjct: 335 IKGGENLWELAKKTYTAFASSKDNDKHFTDLAALSFVMCKAIENPALTPSSSLRSSFMTV 394
Query: 194 FLGEPAKREWQSKQAEMKGLNIAGTLGPLASMHGIGPCFSTCEYMSEGKEGPELCVHLTF 373
F + ++ Q E L + +G AS+HGIGP + + + G+ CV +
Sbjct: 395 F-EDTIIDDYNDMQRE---LGVDDYIG-CASVHGIGPSIAIFDTIRNGRLD---CV-CVY 445
Query: 374 ATPVYTRDFM 403
+P++TR+ M
Sbjct: 446 PSPLHTREQM 455
>ref|XP_001781819.1| predicted protein [Physcomitrella patens]
gi|162666726|gb|EDQ53373.1| predicted protein
[Physcomitrella patens]
Length = 459
Score = 57.4 bits (137), Expect = 5e-06
Identities = 38/136 (27%), Positives = 61/136 (44%)
Frame = +2
Query: 20 EEVSFWELAKTISAKTAKEMKKHKHFSELPVLAMLIAQVIKRPSLTPGMSKRSGLFTCFL 199
E SFW+LA S +K KHF+++ L L+ Q ++ P+LTP S R+ + +
Sbjct: 327 EPESFWDLATRCSEDFDTAIKNRKHFTDMGDLNALMVQAMRFPNLTPSGSLRTSVLSTMF 386
Query: 200 GEPAKREWQSKQAEMKGLNIAGTLGPLASMHGIGPCFSTCEYMSEGKEGPELCVHLTFAT 379
+ E + + L +S HG+GPC + +M E L F++
Sbjct: 387 TPVV----EDLGEEAAAVGVKDYLS-CSSTHGVGPCLALFPFMRES----ALQFSFVFSS 437
Query: 380 PVYTRDFMHGFATSAI 427
P+Y+R M S I
Sbjct: 438 PLYSRTLMQSLVDSII 453
>gb|AAK59422.1| unknown protein [Arabidopsis thaliana]
Length = 475
Score = 57.4 bits (137), Expect = 5e-06
Identities = 39/143 (27%), Positives = 68/143 (47%)
Frame = +2
Query: 23 EVSFWELAKTISAKTAKEMKKHKHFSELPVLAMLIAQVIKRPSLTPGMSKRSGLFTCFLG 202
E W+LAK +K F+++ L L+ + I+ P+LTP S R+ + F
Sbjct: 338 EEKLWDLAKRCYDSFTSSKNSNKQFTDMSDLNFLMCKAIENPNLTPSSSLRTAFISIF-E 396
Query: 203 EPAKREWQSKQAEMKGLNIAGTLGPLASMHGIGPCFSTCEYMSEGKEGPELCVHLTFATP 382
+P E S + E+ L + +G AS+HG+GP + + + +GK L + +P
Sbjct: 397 DPVIDE--SPEPELASLGVQDYIG-CASIHGVGPSVAVFDALRDGK----LDCAFVYPSP 449
Query: 383 VYTRDFMHGFATSAIDLLLSECA 451
+++R+ M G +LL A
Sbjct: 450 LHSREQMDGLIQHMKTILLEGSA 472
>ref|NP_566970.1| uncharacterized protein [Arabidopsis thaliana]
gi|23296330|gb|AAN13043.1| unknown protein [Arabidopsis
thaliana] gi|332645448|gb|AEE78969.1| uncharacterized
protein AT3G52610 [Arabidopsis thaliana]
Length = 475
Score = 57.4 bits (137), Expect = 5e-06
Identities = 39/143 (27%), Positives = 68/143 (47%)
Frame = +2
Query: 23 EVSFWELAKTISAKTAKEMKKHKHFSELPVLAMLIAQVIKRPSLTPGMSKRSGLFTCFLG 202
E W+LAK +K F+++ L L+ + I+ P+LTP S R+ + F
Sbjct: 338 EEKLWDLAKRCYDSFTSSKNSNKQFTDMSDLNFLMCKAIENPNLTPSSSLRTAFISIF-E 396
Query: 203 EPAKREWQSKQAEMKGLNIAGTLGPLASMHGIGPCFSTCEYMSEGKEGPELCVHLTFATP 382
+P E S + E+ L + +G AS+HG+GP + + + +GK L + +P
Sbjct: 397 DPVIDE--SPEPELASLGVQDYIG-CASIHGVGPSVAVFDALRDGK----LDCAFVYPSP 449
Query: 383 VYTRDFMHGFATSAIDLLLSECA 451
+++R+ M G +LL A
Sbjct: 450 LHSREQMDGLIQHMKTILLEGSA 472
>emb|CAB89222.1| putative protein [Arabidopsis thaliana]
Length = 465
Score = 57.4 bits (137), Expect = 5e-06
Identities = 39/143 (27%), Positives = 68/143 (47%)
Frame = +2
Query: 23 EVSFWELAKTISAKTAKEMKKHKHFSELPVLAMLIAQVIKRPSLTPGMSKRSGLFTCFLG 202
E W+LAK +K F+++ L L+ + I+ P+LTP S R+ + F
Sbjct: 328 EEKLWDLAKRCYDSFTSSKNSNKQFTDMSDLNFLMCKAIENPNLTPSSSLRTAFISIF-E 386
Query: 203 EPAKREWQSKQAEMKGLNIAGTLGPLASMHGIGPCFSTCEYMSEGKEGPELCVHLTFATP 382
+P E S + E+ L + +G AS+HG+GP + + + +GK L + +P
Sbjct: 387 DPVIDE--SPEPELASLGVQDYIG-CASIHGVGPSVAVFDALRDGK----LDCAFVYPSP 439
Query: 383 VYTRDFMHGFATSAIDLLLSECA 451
+++R+ M G +LL A
Sbjct: 440 LHSREQMDGLIQHMKTILLEGSA 462
>gb|ESW17287.1| hypothetical protein PHAVU_007G226900g [Phaseolus vulgaris]
gi|561018484|gb|ESW17288.1| hypothetical protein
PHAVU_007G226900g [Phaseolus vulgaris]
Length = 471
Score = 57.0 bits (136), Expect = 7e-06
Identities = 43/143 (30%), Positives = 67/143 (46%), Gaps = 1/143 (0%)
Frame = +2
Query: 23 EVSFWELAKTISAKTAKEMKKHKHFSELPVLAMLIAQVIKRPSLTPGMSKRSGLFTCFLG 202
E + WELAK M +KHFS++ L L+ + I P LTP S R+ L + F
Sbjct: 330 EEALWELAKRSYTSFINAMNCNKHFSDMSDLNYLMCKAIDNPGLTPSSSLRTALISVF-E 388
Query: 203 EPAKREWQSKQAEMKG-LNIAGTLGPLASMHGIGPCFSTCEYMSEGKEGPELCVHLTFAT 379
+P + AEM G + + +G AS HG+GP + + + GK L +
Sbjct: 389 DPVFGD----SAEMHGEIGLEDYVG-CASAHGVGPSIALFDTIRNGK----LDCACIYPW 439
Query: 380 PVYTRDFMHGFATSAIDLLLSEC 448
P+++R+ + G LL+ C
Sbjct: 440 PLHSREQIQGLVDHMKRLLVESC 462
>ref|XP_004494048.1| PREDICTED: uncharacterized protein LOC101495207 [Cicer arietinum]
Length = 454
Score = 56.6 bits (135), Expect = 9e-06
Identities = 37/143 (25%), Positives = 69/143 (48%)
Frame = +2
Query: 11 KVKEEVSFWELAKTISAKTAKEMKKHKHFSELPVLAMLIAQVIKRPSLTPGMSKRSGLFT 190
++K W+LAK + A K +KHFS++ L L+ + I+ P LTP S R+ + +
Sbjct: 311 EIKGGEKLWDLAKRTYSAFANSKKSNKHFSDMADLNFLMCKAIENPGLTPSSSLRTAILS 370
Query: 191 CFLGEPAKREWQSKQAEMKGLNIAGTLGPLASMHGIGPCFSTCEYMSEGKEGPELCVHLT 370
F + + K + + +G AS+HG+GP + + + +G CV
Sbjct: 371 VFEDTVV----DNSGKKQKDVGVEDYMG-CASIHGVGPSIAIFDTIRDGSLD---CV-CV 421
Query: 371 FATPVYTRDFMHGFATSAIDLLL 439
+ +P+++R+ M D+L+
Sbjct: 422 YPSPLHSREQMQEVFGKVKDILI 444