BLASTX nr result
ID: Ephedra25_contig00023184
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Ephedra25_contig00023184
(463 letters)
Database: ./nr
37,332,560 sequences; 13,225,080,153 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|XP_006363504.1| PREDICTED: flavanone 7-O-glucoside 2''-O-bet... 101 1e-19
gb|ABR18123.1| unknown [Picea sitchensis] 101 1e-19
gb|EMJ19213.1| hypothetical protein PRUPE_ppa005830mg [Prunus pe... 100 3e-19
ref|XP_002311963.2| hypothetical protein POPTR_0008s02520g [Popu... 99 6e-19
sp|Q5NTH0.1|UGAT_BELPE RecName: Full=Cyanidin-3-O-glucoside 2-O-... 99 8e-19
gb|EMJ21660.1| hypothetical protein PRUPE_ppa005526mg [Prunus pe... 98 1e-18
ref|XP_002265392.1| PREDICTED: cyanidin-3-O-glucoside 2-O-glucur... 97 2e-18
gb|EXC25399.1| Cyanidin-3-O-glucoside 2-O-glucuronosyltransferas... 96 4e-18
gb|EMJ21659.1| hypothetical protein PRUPE_ppa005520mg [Prunus pe... 96 4e-18
gb|AEJ88222.1| UDP-glucose:flavonoid 3-O-glucosyltransferase [Pr... 96 4e-18
gb|EMJ21657.1| hypothetical protein PRUPE_ppa005471mg [Prunus pe... 95 8e-18
gb|EMJ21661.1| hypothetical protein PRUPE_ppa005532mg [Prunus pe... 95 1e-17
gb|AFK79036.1| glycosyltransferase UGT4 [Bupleurum chinense] 95 1e-17
ref|XP_002264771.1| PREDICTED: cyanidin-3-O-glucoside 2-O-glucur... 95 1e-17
ref|XP_006367679.1| PREDICTED: cyanidin-3-O-glucoside 2-O-glucur... 94 1e-17
ref|XP_006360518.1| PREDICTED: cyanidin-3-O-glucoside 2-O-glucur... 94 1e-17
gb|EMJ20340.1| hypothetical protein PRUPE_ppa016015mg [Prunus pe... 94 1e-17
ref|XP_002271587.2| PREDICTED: flavanone 7-O-glucoside 2''-O-bet... 94 1e-17
ref|XP_006424314.1| hypothetical protein CICLE_v10030045mg, part... 94 2e-17
ref|XP_004243636.1| PREDICTED: cyanidin-3-O-glucoside 2-O-glucur... 94 2e-17
>ref|XP_006363504.1| PREDICTED: flavanone 7-O-glucoside
2''-O-beta-L-rhamnosyltransferase-like [Solanum
tuberosum]
Length = 446
Score = 101 bits (251), Expect = 1e-19
Identities = 41/102 (40%), Positives = 70/102 (68%)
Frame = -3
Query: 461 WVPQKKLMEKGCVGGFMSHCGWNSVLQAMQFGFPFVAVPLMFEQGFSARLVTADLGLGLE 282
W PQ K++E +GGF+SHCGW+SV+++M++G P +A+P+ +Q ++RL+ ++G+ +E
Sbjct: 325 WAPQAKILEHSSIGGFVSHCGWSSVMESMKYGVPIIAMPMHLDQPMNSRLIVEEVGMAVE 384
Query: 281 VRRDSQGVIRAQEVCRCVKGVMREEGGGAFKKKAQDMRNIFR 156
V RD +G + +EV + V+ EEGG ++KA M+ I R
Sbjct: 385 VVRDGEGKLHWKEVADVINHVVVEEGGELVREKANHMKEIIR 426
>gb|ABR18123.1| unknown [Picea sitchensis]
Length = 491
Score = 101 bits (251), Expect = 1e-19
Identities = 49/133 (36%), Positives = 79/133 (59%), Gaps = 4/133 (3%)
Frame = -3
Query: 461 WVPQKKLMEKGCVGGFMSHCGWNSVLQAMQFGFPFVAVPLMFEQGFSARLVTADLGLGLE 282
W PQK+++ G F++HCGW+S+ + M G P +A+P+ ++QG +ARL+ +L +G+E
Sbjct: 351 WAPQKEILSHPSTGAFLTHCGWSSLTEGMSVGLPLIALPMQWDQGLNARLIVNELKVGVE 410
Query: 281 VRRDSQGVIRAQEVCRCVKGVMREEGGGAFK---KKAQDMRNIFRSQIL-PPLDGSQASN 114
V R G +++CR V+ VM E G K ++A M ++FR IL GS+
Sbjct: 411 VARRGDGAASREDICRAVRAVMAPEDGEEGKDVRQRASQMGDMFRRTILNGESKGSEERY 470
Query: 113 MDNFVNFLYALSS 75
+D FV L AL++
Sbjct: 471 IDKFVQHLLALAT 483
>gb|EMJ19213.1| hypothetical protein PRUPE_ppa005830mg [Prunus persica]
Length = 441
Score = 100 bits (248), Expect = 3e-19
Identities = 43/111 (38%), Positives = 81/111 (72%)
Frame = -3
Query: 461 WVPQKKLMEKGCVGGFMSHCGWNSVLQAMQFGFPFVAVPLMFEQGFSARLVTADLGLGLE 282
W PQ K++E VGGF+SHCGW+SVL++++FG P +A+P++++Q +ARLV ++G+G+E
Sbjct: 321 WAPQSKILEHYSVGGFVSHCGWSSVLESIKFGVPIIALPMLYDQPINARLV-EEVGVGVE 379
Query: 281 VRRDSQGVIRAQEVCRCVKGVMREEGGGAFKKKAQDMRNIFRSQILPPLDG 129
V+R ++G +++EV + ++ V+ ++ G +KKA ++R+ +++ DG
Sbjct: 380 VKRTAEGSFQSEEVAKVIRDVVVDKIGEGVRKKALELRDNMKNKEDAERDG 430
>ref|XP_002311963.2| hypothetical protein POPTR_0008s02520g [Populus trichocarpa]
gi|550332256|gb|EEE89330.2| hypothetical protein
POPTR_0008s02520g [Populus trichocarpa]
Length = 419
Score = 99.0 bits (245), Expect = 6e-19
Identities = 42/122 (34%), Positives = 76/122 (62%)
Frame = -3
Query: 461 WVPQKKLMEKGCVGGFMSHCGWNSVLQAMQFGFPFVAVPLMFEQGFSARLVTADLGLGLE 282
W PQK+++ +GGF+SHCGW SVL++M+FG P +A+P+ +Q +A + ++G+GLE
Sbjct: 285 WAPQKRILSHPSIGGFLSHCGWGSVLESMKFGVPLIAMPMHIDQPLNAEFL-VEIGVGLE 343
Query: 281 VRRDSQGVIRAQEVCRCVKGVMREEGGGAFKKKAQDMRNIFRSQILPPLDGSQASNMDNF 102
++RD G I +EV R ++ + E G +KKA+++ + R + +D + ++ +
Sbjct: 344 IKRDKNGKIEREEVARVIRDLAGERTGEHLRKKARELSDCIRDKAGQEIDEEKTQSLLGW 403
Query: 101 VN 96
N
Sbjct: 404 SN 405
>sp|Q5NTH0.1|UGAT_BELPE RecName: Full=Cyanidin-3-O-glucoside 2-O-glucuronosyltransferase;
Short=BpUGAT; AltName: Full=UDP-glucuronic
acid:anthocyanin glucuronosyltransferase
gi|56550539|dbj|BAD77944.1| UDP-glucuronic
acid:anthocyanin glucuronosyltransferase [Bellis
perennis]
Length = 438
Score = 98.6 bits (244), Expect = 8e-19
Identities = 40/117 (34%), Positives = 77/117 (65%)
Frame = -3
Query: 461 WVPQKKLMEKGCVGGFMSHCGWNSVLQAMQFGFPFVAVPLMFEQGFSARLVTADLGLGLE 282
WVPQ ++ GGF+SHCGW+S ++++++G P +A+P+ F+Q ++ARL+ +G G+E
Sbjct: 315 WVPQANILSHSSTGGFISHCGWSSTMESIRYGVPIIAMPMQFDQPYNARLMET-VGAGIE 373
Query: 281 VRRDSQGVIRAQEVCRCVKGVMREEGGGAFKKKAQDMRNIFRSQILPPLDGSQASNM 111
V RD +G ++ +E+ V+ V+ E+ G + ++KA+++ I + + +DG N+
Sbjct: 374 VGRDGEGRLKREEIAAVVRKVVVEDSGESIREKAKELGEIMKKNMEAEVDGIVIENL 430
>gb|EMJ21660.1| hypothetical protein PRUPE_ppa005526mg [Prunus persica]
Length = 456
Score = 98.2 bits (243), Expect = 1e-18
Identities = 44/111 (39%), Positives = 75/111 (67%)
Frame = -3
Query: 461 WVPQKKLMEKGCVGGFMSHCGWNSVLQAMQFGFPFVAVPLMFEQGFSARLVTADLGLGLE 282
W PQ K+++ VGGF+SHCGWNSVL++++FG P +A+P+ +Q +ARLV ++G+G+E
Sbjct: 332 WAPQAKILQHSSVGGFVSHCGWNSVLESIKFGVPIIAMPMHLDQPINARLV-EEVGVGVE 390
Query: 281 VRRDSQGVIRAQEVCRCVKGVMREEGGGAFKKKAQDMRNIFRSQILPPLDG 129
V+R +G ++ +EV + ++ V E+ G +KKA +R+ + +DG
Sbjct: 391 VKRTGEGSLQREEVAKVIRDVFVEKIGEGVRKKALKIRDNMNKKEDEEIDG 441
>ref|XP_002265392.1| PREDICTED: cyanidin-3-O-glucoside 2-O-glucuronosyltransferase-like
[Vitis vinifera]
Length = 491
Score = 97.4 bits (241), Expect = 2e-18
Identities = 41/96 (42%), Positives = 69/96 (71%)
Frame = -3
Query: 461 WVPQKKLMEKGCVGGFMSHCGWNSVLQAMQFGFPFVAVPLMFEQGFSARLVTADLGLGLE 282
W PQKK++ +GGF+SHCGW SV+++M FG P VA+P+ +Q F+A+LV A G+G+E
Sbjct: 327 WAPQKKILRHSSIGGFVSHCGWGSVMESMNFGVPIVAMPMHLDQPFNAKLVEAH-GVGIE 385
Query: 281 VRRDSQGVIRAQEVCRCVKGVMREEGGGAFKKKAQD 174
V+RD G ++ +E+ + +K V+ ++ G ++KA++
Sbjct: 386 VKRDENGKLQREEIAKVIKEVVVKKCGEIVRQKARE 421
>gb|EXC25399.1| Cyanidin-3-O-glucoside 2-O-glucuronosyltransferase [Morus
notabilis]
Length = 465
Score = 96.3 bits (238), Expect = 4e-18
Identities = 40/97 (41%), Positives = 71/97 (73%)
Frame = -3
Query: 461 WVPQKKLMEKGCVGGFMSHCGWNSVLQAMQFGFPFVAVPLMFEQGFSARLVTADLGLGLE 282
W PQ+++++ +GGF+SHCGW+SV+++M+FG P +A+P+ +Q +ARLV ++G+G E
Sbjct: 338 WAPQREVLKSKSIGGFVSHCGWSSVMESMKFGVPIIAMPMHLDQPINARLV-EEVGVGFE 396
Query: 281 VRRDSQGVIRAQEVCRCVKGVMREEGGGAFKKKAQDM 171
V RD G I+++E+ + V+ V+ E+ G + + KA +M
Sbjct: 397 VERDENGRIQSEELAKAVRKVVLEKSGESVRNKAVEM 433
>gb|EMJ21659.1| hypothetical protein PRUPE_ppa005520mg [Prunus persica]
Length = 456
Score = 96.3 bits (238), Expect = 4e-18
Identities = 41/94 (43%), Positives = 69/94 (73%)
Frame = -3
Query: 461 WVPQKKLMEKGCVGGFMSHCGWNSVLQAMQFGFPFVAVPLMFEQGFSARLVTADLGLGLE 282
W PQ K+++ VGGF+SHCGWNSVL++++FG P +A+P+ +Q +ARLV ++G+G+E
Sbjct: 332 WAPQAKILQHSSVGGFVSHCGWNSVLESIKFGVPIIAMPMHLDQPINARLV-EEVGVGVE 390
Query: 281 VRRDSQGVIRAQEVCRCVKGVMREEGGGAFKKKA 180
V+R +G ++ +EV + ++ V+ E+ G +KKA
Sbjct: 391 VKRTGEGSLQREEVAKVIRDVVVEKFGEGVRKKA 424
>gb|AEJ88222.1| UDP-glucose:flavonoid 3-O-glucosyltransferase [Prunus persica]
Length = 456
Score = 96.3 bits (238), Expect = 4e-18
Identities = 41/94 (43%), Positives = 69/94 (73%)
Frame = -3
Query: 461 WVPQKKLMEKGCVGGFMSHCGWNSVLQAMQFGFPFVAVPLMFEQGFSARLVTADLGLGLE 282
W PQ K+++ VGGF+SHCGWNSVL++++FG P +A+P+ +Q +ARLV ++G+G+E
Sbjct: 332 WAPQAKILQHSSVGGFVSHCGWNSVLESIKFGVPIIAMPMHLDQPINARLV-EEVGVGVE 390
Query: 281 VRRDSQGVIRAQEVCRCVKGVMREEGGGAFKKKA 180
V+R +G ++ +EV + ++ V+ E+ G +KKA
Sbjct: 391 VKRTGEGSLQREEVAKVIRDVVVEKFGEGVRKKA 424
>gb|EMJ21657.1| hypothetical protein PRUPE_ppa005471mg [Prunus persica]
Length = 459
Score = 95.1 bits (235), Expect = 8e-18
Identities = 39/104 (37%), Positives = 76/104 (73%)
Frame = -3
Query: 461 WVPQKKLMEKGCVGGFMSHCGWNSVLQAMQFGFPFVAVPLMFEQGFSARLVTADLGLGLE 282
W PQ +++ VGGF+SHCGW+SVL++++FG P +A+P+ +Q +ARLV ++G+G+E
Sbjct: 332 WAPQANILKHSRVGGFVSHCGWSSVLESIKFGVPIIAMPMHLDQPINARLV-EEVGVGVE 390
Query: 281 VRRDSQGVIRAQEVCRCVKGVMREEGGGAFKKKAQDMRNIFRSQ 150
V+R +G+++ +E+ + ++ V+ E+ G +KKA ++R+ +++
Sbjct: 391 VKRTGEGILQREEMAKVIRKVVVEKIGEGMRKKALELRDNMKNK 434
>gb|EMJ21661.1| hypothetical protein PRUPE_ppa005532mg [Prunus persica]
Length = 456
Score = 94.7 bits (234), Expect = 1e-17
Identities = 43/116 (37%), Positives = 76/116 (65%), Gaps = 5/116 (4%)
Frame = -3
Query: 461 WVPQKKLMEKGCVGGFMSHCGWNSVLQAMQFGFPFVAVPLMFEQGFSARLVTADLGLGLE 282
W PQ K+++ GGF+SHCGW+SVL++++FG P VA+P+ +Q +AR+V D+G+G+E
Sbjct: 329 WAPQAKVLKHSSAGGFVSHCGWSSVLESIKFGVPIVAMPMHLDQPINARIV-EDVGVGVE 387
Query: 281 VRR-----DSQGVIRAQEVCRCVKGVMREEGGGAFKKKAQDMRNIFRSQILPPLDG 129
V+R + G ++ E+ + ++ V+ EE G K+KA ++R+ + + +DG
Sbjct: 388 VKRMGGGGNENGRLKRDEIAKVIRDVVVEENGQGLKRKAMELRDNMKKREDEEIDG 443
>gb|AFK79036.1| glycosyltransferase UGT4 [Bupleurum chinense]
Length = 453
Score = 94.7 bits (234), Expect = 1e-17
Identities = 43/104 (41%), Positives = 70/104 (67%)
Frame = -3
Query: 461 WVPQKKLMEKGCVGGFMSHCGWNSVLQAMQFGFPFVAVPLMFEQGFSARLVTADLGLGLE 282
W PQ K+++ VGGF++HCGWNS+L++M+ G VA P+ +Q F+ARLV DLG+G E
Sbjct: 329 WAPQAKILKHSSVGGFVTHCGWNSILESMKLGVAIVATPMQLDQYFNARLV-VDLGVGKE 387
Query: 281 VRRDSQGVIRAQEVCRCVKGVMREEGGGAFKKKAQDMRNIFRSQ 150
V RD +G ++ +EV + ++ V+ E G ++KA+++ R +
Sbjct: 388 VVRDIEGRLQREEVAKVIREVVVENIGENVREKAKELSKCMRDK 431
>ref|XP_002264771.1| PREDICTED: cyanidin-3-O-glucoside 2-O-glucuronosyltransferase
[Vitis vinifera]
Length = 457
Score = 94.7 bits (234), Expect = 1e-17
Identities = 39/104 (37%), Positives = 72/104 (69%)
Frame = -3
Query: 461 WVPQKKLMEKGCVGGFMSHCGWNSVLQAMQFGFPFVAVPLMFEQGFSARLVTADLGLGLE 282
W PQKK++ +GGF+SHCGW+S++++++FG P VA+P+ +Q F+A+L+ A +G+G+E
Sbjct: 329 WAPQKKILGHTSIGGFVSHCGWSSIMESIKFGVPIVAIPMQIDQPFNAKLLEA-VGVGVE 387
Query: 281 VRRDSQGVIRAQEVCRCVKGVMREEGGGAFKKKAQDMRNIFRSQ 150
V+R+ + +E+ R +K V+ E+ G ++K ++M R +
Sbjct: 388 VKRNEDRRLEREEIARVIKEVVVEKSGENVRRKVREMSENMRKK 431
>ref|XP_006367679.1| PREDICTED: cyanidin-3-O-glucoside 2-O-glucuronosyltransferase-like
[Solanum tuberosum]
Length = 443
Score = 94.4 bits (233), Expect = 1e-17
Identities = 39/111 (35%), Positives = 74/111 (66%)
Frame = -3
Query: 461 WVPQKKLMEKGCVGGFMSHCGWNSVLQAMQFGFPFVAVPLMFEQGFSARLVTADLGLGLE 282
W PQ +++ +GGF+SHCGW+S +++M+FG P +A+P+ +Q +ARLV +G+G+E
Sbjct: 322 WAPQALILQHPSIGGFVSHCGWSSFMESMKFGVPIIAMPMHIDQPMNARLVEY-IGVGVE 380
Query: 281 VRRDSQGVIRAQEVCRCVKGVMREEGGGAFKKKAQDMRNIFRSQILPPLDG 129
+D G ++++E+ + ++ V+ EE G A +KKA+++ ++ +DG
Sbjct: 381 AAKDEDGKLQSEEIAKAIREVLVEESGEAVRKKAKELSEKMNAKEDEEIDG 431
>ref|XP_006360518.1| PREDICTED: cyanidin-3-O-glucoside 2-O-glucuronosyltransferase-like
[Solanum tuberosum]
Length = 437
Score = 94.4 bits (233), Expect = 1e-17
Identities = 39/111 (35%), Positives = 74/111 (66%)
Frame = -3
Query: 461 WVPQKKLMEKGCVGGFMSHCGWNSVLQAMQFGFPFVAVPLMFEQGFSARLVTADLGLGLE 282
W PQ +++ +GGF+SHCGW+S +++M+FG P +A+P+ +Q +ARLV +G+G+E
Sbjct: 316 WAPQALILQHPSIGGFVSHCGWSSFMESMKFGVPIIAMPMHIDQPMNARLVEY-IGVGVE 374
Query: 281 VRRDSQGVIRAQEVCRCVKGVMREEGGGAFKKKAQDMRNIFRSQILPPLDG 129
+D G ++++E+ + ++ V+ EE G A +KKA+++ ++ +DG
Sbjct: 375 AAKDEDGKLQSEEIAKAIREVLVEESGEAVRKKAKELSEKMNAKEDEEIDG 425
>gb|EMJ20340.1| hypothetical protein PRUPE_ppa016015mg [Prunus persica]
Length = 451
Score = 94.4 bits (233), Expect = 1e-17
Identities = 39/104 (37%), Positives = 75/104 (72%)
Frame = -3
Query: 461 WVPQKKLMEKGCVGGFMSHCGWNSVLQAMQFGFPFVAVPLMFEQGFSARLVTADLGLGLE 282
W PQ K++ VGGF+SHCGW+SVL++++FG P +A+P+ +Q ++RLV ++G+G+E
Sbjct: 332 WAPQAKILNHSSVGGFVSHCGWSSVLESIKFGVPIIAMPMHLDQPINSRLV-EEVGVGVE 390
Query: 281 VRRDSQGVIRAQEVCRCVKGVMREEGGGAFKKKAQDMRNIFRSQ 150
V+R ++G + +EV + ++ V+ ++ G +KKA ++R+ +++
Sbjct: 391 VKRTAEGSLERKEVAKAIRDVVAKKIGEGVRKKALEIRDNMKNK 434
>ref|XP_002271587.2| PREDICTED: flavanone 7-O-glucoside
2''-O-beta-L-rhamnosyltransferase-like [Vitis vinifera]
Length = 434
Score = 94.4 bits (233), Expect = 1e-17
Identities = 39/104 (37%), Positives = 70/104 (67%)
Frame = -3
Query: 461 WVPQKKLMEKGCVGGFMSHCGWNSVLQAMQFGFPFVAVPLMFEQGFSARLVTADLGLGLE 282
W PQ+K++ +GGF+SHCGW+SV++ M+FG P +A+P+ +Q +A+LV A +G+G E
Sbjct: 314 WAPQRKILGHSSIGGFVSHCGWSSVMEGMKFGVPIIAMPMHLDQPINAKLVEA-VGVGRE 372
Query: 281 VRRDSQGVIRAQEVCRCVKGVMREEGGGAFKKKAQDMRNIFRSQ 150
V+RD + +E+ + +K V+ E+ G ++KA+++ R +
Sbjct: 373 VKRDENRKLEREEIAKVIKEVVGEKNGENVRRKARELSETLRKK 416
>ref|XP_006424314.1| hypothetical protein CICLE_v10030045mg, partial [Citrus clementina]
gi|557526248|gb|ESR37554.1| hypothetical protein
CICLE_v10030045mg, partial [Citrus clementina]
Length = 399
Score = 94.0 bits (232), Expect = 2e-17
Identities = 42/98 (42%), Positives = 68/98 (69%), Gaps = 1/98 (1%)
Frame = -3
Query: 461 WVPQKKLMEKGCVGGFMSHCGWNSVLQAMQFGFPFVAVPLMFEQGFSARLVTADLGLGLE 282
W PQ K++ G +GGF+SHCGW S ++ + +G P +AVP++ +Q F+A++V AD+G+GLE
Sbjct: 276 WAPQAKILGHGSIGGFISHCGWGSTVEGIMYGVPIIAVPMVLDQLFNAKMV-ADIGVGLE 334
Query: 281 VRRDS-QGVIRAQEVCRCVKGVMREEGGGAFKKKAQDM 171
V RD +R +E+ R K V+ +E G K+KA+++
Sbjct: 335 VPRDEINQRVRKEELARVFKQVVEQEEGQQIKRKAKEL 372
>ref|XP_004243636.1| PREDICTED: cyanidin-3-O-glucoside 2-O-glucuronosyltransferase-like
[Solanum lycopersicum]
Length = 441
Score = 94.0 bits (232), Expect = 2e-17
Identities = 40/111 (36%), Positives = 73/111 (65%)
Frame = -3
Query: 461 WVPQKKLMEKGCVGGFMSHCGWNSVLQAMQFGFPFVAVPLMFEQGFSARLVTADLGLGLE 282
W PQ+++++ +GGF++HCGWNS L++++FG P +A+P++++Q +ARL+ + G+ +E
Sbjct: 316 WAPQQRILKHSSIGGFVTHCGWNSTLESIEFGVPIIAMPMLYDQPLNARLMVEN-GVAVE 374
Query: 281 VRRDSQGVIRAQEVCRCVKGVMREEGGGAFKKKAQDMRNIFRSQILPPLDG 129
V RD +G + + +K V+R+E G +KK ++ RSQ +DG
Sbjct: 375 VPRDEKGNLDRVNIAEKIKHVIRDETGENLRKKMNNLGENVRSQREEEMDG 425