BLASTX nr result
ID: Ephedra25_contig00013698
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Ephedra25_contig00013698
(3497 letters)
Database: ./nr
37,332,560 sequences; 13,225,080,153 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gb|EWC87671.1| hypothetical protein PFNF54_03519 [Plasmodium fal... 132 1e-27
ref|YP_006070601.1| hypothetical protein SALIVA_1456 [Streptococ... 129 7e-27
ref|WP_000466197.1| hypothetical protein [Streptococcus mitis] g... 128 2e-26
ref|NP_001024204.1| Protein TTN-1, isoform g [Caenorhabditis ele... 125 1e-25
ref|NP_001024201.1| Protein TTN-1, isoform d [Caenorhabditis ele... 125 1e-25
ref|NP_001024203.1| Protein TTN-1, isoform f [Caenorhabditis ele... 125 1e-25
ref|NP_001024202.1| Protein TTN-1, isoform e [Caenorhabditis ele... 125 1e-25
gb|ETW48434.1| hypothetical protein PFMALIP_03519 [Plasmodium fa... 124 4e-25
ref|WP_010169103.1| hypothetical protein [Epulopiscium sp. 'N.t.... 120 4e-24
gb|AAF15293.3| erythrocyte membrane-associated giant protein ant... 120 4e-24
ref|XP_002603167.1| hypothetical protein BRAFLDRAFT_63199 [Branc... 119 1e-23
gb|ETW56318.1| hypothetical protein PFUGPA_01683 [Plasmodium fal... 118 2e-23
gb|ETW30239.1| hypothetical protein PFFCH_02322 [Plasmodium falc... 118 2e-23
ref|WP_003093445.1| flagellar biosynthesis protein FliS [Strepto... 118 2e-23
gb|EWC75624.1| hypothetical protein C923_03695 [Plasmodium falci... 117 4e-23
gb|ETW41847.1| hypothetical protein PFNF135_03775 [Plasmodium fa... 116 6e-23
ref|NP_725510.2| Stretchin-Mlck, isoform V [Drosophila melanogas... 115 2e-22
ref|NP_001261019.1| Stretchin-Mlck, isoform U [Drosophila melano... 115 2e-22
ref|NP_001188955.2| Stretchin-Mlck, isoform T [Drosophila melano... 115 2e-22
ref|NP_001261018.1| Stretchin-Mlck, isoform S [Drosophila melano... 115 2e-22
>gb|EWC87671.1| hypothetical protein PFNF54_03519 [Plasmodium falciparum NF54]
Length = 3531
Score = 132 bits (331), Expect = 1e-27
Identities = 229/1251 (18%), Positives = 513/1251 (41%), Gaps = 97/1251 (7%)
Frame = -3
Query: 3468 EKTGSVNQGVCNLSSSSTKIENQ----ENAGSTVTAVRSENSMVTQGLEKESNVIVNVVI 3301
E+ GS + V SS ++ EN G + +++ + + + E + V+
Sbjct: 1502 EEEGSATEEVVEEGLSSDNVQKSKGVIENVGEIYSVKTAKDESMNEKIPLEKSSFVDDES 1561
Query: 3300 GDNKKCTAGSLLEKKDNVEVVIPSVKVRKKRDPASCSKTISSCKPRKASINKTNENLNMP 3121
+ T +E ++ +++ + + + ++ I++ +T NL
Sbjct: 1562 FKGQGPTDNVSVEDVNSEDIINEHTPLEETKIEELPTEYITTADIHTKGETETKYNLIYE 1621
Query: 3120 STQINKQELAGVIVLSDNSDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSF 2941
+IN++ +++ V + V E +++ + +++V+ + N E
Sbjct: 1622 --KINEEVEKAKFQEEKITENIPVERESVTE--DIVQEPSLAQEVEQKESDTNEIEETKL 1677
Query: 2940 ANDAALNAKLQGSDKMKNTDVATENCVLKDK--------EKVSHTSNISQEESSGANDVA 2785
AN+ + + ++ + TE + +D+ E+VS + I +EE S + ++
Sbjct: 1678 ANEKIIPEVSVTENVVEKEGLDTEEVLEEDESITEEIVEEEVSSSEEIVEEEESSSEEIV 1737
Query: 2784 VNEKLKASDIEKGVDTTVKD-ANHTKKGNVSIMVGPIKQQKNVAKGISMNEK-MKGKGSV 2611
E+ + +I + +++ ++ + + I+ + + + +S E+ ++ +GSV
Sbjct: 1738 EEEESSSEEIVEEEESSSEEIVEEEESSSEEIVEEEESSSEEIIEEVSSTEEVLEEEGSV 1797
Query: 2610 AKNATAINAATHLEKKNIGNTLQ-ALDVENKNVEVTI--EGKIQGKAKRSESKTCSSEKK 2440
+ +T E K+IG+ + L+ E E + +G + + +ES T +
Sbjct: 1798 TEEIVEEEVSTTEEVKDIGSVSEEVLEEEGFGTEEFVGQQGSVIEEIVETESSTEKVLED 1857
Query: 2439 NIGNTLQALDEENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKE 2260
N + + EE + + ++ K E + +V K +E
Sbjct: 1858 VGSNVEEIVQEEGPVAQEIVHEEVSTTEKHDEVDRSTTEEIV----EKVGSVSEEIIVEE 1913
Query: 2259 FTMSTDVLKDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTEINVAVFTEKG 2080
+ S +++++ V E+ V +L G + V ++ + +V+ D E V ++G
Sbjct: 1914 VSASEEIVEEGSVTEEVVEEEKLINEVGETESVTEEIVQKEVS----DAE---EVLGQEG 1966
Query: 2079 SISNTLHILEDINKK---KEATNEEKLPEKGELSAELKPDSDSRSEFVATCVNEVSGQVN 1909
S++ + E I ++ E + E++ + G + E+K + E V + G V
Sbjct: 1967 SMNEEILEKESIVEEIVGPEGSVTEEIVDHGSFAEEVKEE-----ELVTEEAVQYEGSVT 2021
Query: 1908 NLSIEEFTMSRDRPEDAEIFKETVGTHQLEEKVGSTYAVPSGEKRDVNLILKEVVTAAND 1729
EE +++ + + F E + EEK +T + E D I+ EV + D
Sbjct: 2022 EEIKEEESITENEAIEESAFAEII-----EEKGPNTDEIVKEEGLDTEEIVNEV--SVTD 2074
Query: 1728 SNLTEEKTISNTA----HTADDVRKEMEVAIEERMQEKGVSYSEKKAGTKSDTVGGRVDE 1561
+ EEK ++ + + E+E + E + E+ S +EK + + T +DE
Sbjct: 2075 EVIEEEKLVNEQIVGEERSVTEKPVEVERSATEDLVEEEASVTEKVSVHEGSTTEQILDE 2134
Query: 1560 MSGQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDTNEAAVDDKIN-PEDMMKK 1384
S + + +V+VD K+ E+ S D + E+ E V+++ + PE+++++
Sbjct: 2135 --------SVAEEIVEEEVSVDDKIIEEEVSVDEVVEEEGSVIEEIVEEEESVPEEILEE 2186
Query: 1383 V---------DTAINDAIF-TEKKIISNIIQISDDENKSTGITAEENMLEKGKLNSEI-- 1240
D + DA E +I I +I D E T E ++E G N +I
Sbjct: 2187 ELSGSEEVLEDEWVTDAFMGQEGSVIEEIEEIVDGEGSIT-----EEIVEDGSANEKIVE 2241
Query: 1239 -KTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKCSVSH----RRQEQIG 1075
+ R E+L + + + S E + + TV + + E ++ + +E I
Sbjct: 2242 EEPSRVEEVLGKEGFVIEEIIEEGSVIEQVEDTKTVSEKSE-ESSAIEEVKEVKEEESIS 2300
Query: 1074 HK---NDNAVIENLQAYAVNNCDTGAKDGNFTEK--ENASKIVSSLHEDIKCTTEVRIAG 910
K + +V E + + + KD + TE E + + E TEV A
Sbjct: 2301 EKIVEKEESVTEEIVRQEESTTEKIVKDVSPTEDFVEQTDSVTEKVIEQEGSNTEV--AE 2358
Query: 909 ELHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVGTDV--- 739
++ EK E + +V V + + V++ + ++ + E+ E+ V V
Sbjct: 2359 DVEEKESASDEHEQEDV--SVNAQVTYEKKSVTKEIVDEVSRTEEIVEENGSVTEGVDET 2416
Query: 738 --VTYQLQEPSGDTNQVVVD----EAVNKDEAAAKDCPPTGD--EKVGNIAYSLYEENIV 583
VT ++ E + T +VV D E V +D + ++ G E++ S+ EE IV
Sbjct: 2417 GSVTEEIIEEATVTEEVVEDGSVTEEVVEDGSVIQEVVEDGSVTEEIVQENGSVTEE-IV 2475
Query: 582 KKETAIDEKMQEKWQLKADA------ASEIVARFVNEESGYARQLPTEKLAMSTDTVGDY 421
++E +++E+++E+ + + E V + +E ++ + +++ + V +
Sbjct: 2476 EEEGSVNEEVEEEVSVSGEVDETEYVTEESVTEELVDEGSVTEEVVEQGGSIAQEIVEEE 2535
Query: 420 KISEKDIVSHLSQEQIHDKD--------------------------EVVDETIHATDTVN 319
+E+ I + E++ +K+ EVV+E I T+
Sbjct: 2536 SATEEIIRDETNVEEVLEKEGSATEEIVQDGSGTNDFVGKQGSVIEEVVEEEISTTEEKL 2595
Query: 318 KDETAATDDTLSEKEKENGNLKTECSVESTSAIAAGYARQLSTEELAMSTDIEEDYK--- 148
K+E +A ++ + E+ L+ E+ ++ E + + DI E+ +
Sbjct: 2596 KEEASAIEEFVEEESIREDVLEESLVTENVVGQQESVTEEIVDGEGSFTEDIVEEEESVT 2655
Query: 147 ----ISEKDIVSHLLQEQVHDKDEVVGETIHATDTVNKDETAATDDTLSEK 7
+ E+ + +++++ +E+V + T+ + +DE + T++ + E+
Sbjct: 2656 EEIVVDEESVTKEIVEDEELVTEEIVEDEGSFTEEIVEDEGSFTEEVIEER 2706
Score = 108 bits (270), Expect = 2e-20
Identities = 218/1142 (19%), Positives = 454/1142 (39%), Gaps = 141/1142 (12%)
Frame = -3
Query: 3039 KVKEANTVIKGATSSKKVKISSTGENS-QERNSFANDAALNAKLQGSDKMKNTDV----- 2878
++ E +VI+ +K V S ++ +E + +++ K+ ++ ++
Sbjct: 2260 EIIEEGSVIEQVEDTKTVSEKSEESSAIEEVKEVKEEESISEKIVEKEESVTEEIVRQEE 2319
Query: 2877 ATENCVLKD----KEKVSHTSNISQE--ESSGAN-DVA--VNEKLKASDIEKGVDTTVKD 2725
+T ++KD ++ V T +++++ E G+N +VA V EK ASD + D +V
Sbjct: 2320 STTEKIVKDVSPTEDFVEQTDSVTEKVIEQEGSNTEVAEDVEEKESASDEHEQEDVSVNA 2379
Query: 2724 ANHTKKGNVSIMVGPIKQQKNVAKGISMNEKM-KGKGSVAKNATAINAATHLEKKNIGNT 2548
+K +V+ K + +S E++ + GSV + + T + T
Sbjct: 2380 QVTYEKKSVT---------KEIVDEVSRTEEIVEENGSVTEGVDETGSVTEEIIEEATVT 2430
Query: 2547 LQALDVENKNVEVTIEGKIQGKAKRSESKTCSSEKKNIGNTLQALDEENKNVEVTIDRKI 2368
+ ++ + EV +G + + S T ++N G+ + + EE +V ++ ++
Sbjct: 2431 EEVVEDGSVTEEVVEDGSVIQEVVEDGSVTEEIVQEN-GSVTEEIVEEEGSVNEEVEEEV 2489
Query: 2367 QGKGKRSESK-----TGSIPVMVAGCVNKASCEKFNQSAKEF----TMSTDVLKDA---- 2227
G+ E++ + + ++ G V + E+ A+E + + ++++D
Sbjct: 2490 SVSGEVDETEYVTEESVTEELVDEGSVTEEVVEQGGSIAQEIVEEESATEEIIRDETNVE 2549
Query: 2226 KVFEKD-VATHQL-EKGSGSNDVVIDKNINAKVAVEKVDTEINVAVFTEKGSISNTLHIL 2053
+V EK+ AT ++ + GSG+ND V V E V+ EI+ K S +
Sbjct: 2550 EVLEKEGSATEEIVQDGSGTNDFV---GKQGSVIEEVVEEEISTTEEKLKEEASAIEEFV 2606
Query: 2052 EDINKKKEATNEEKLPEK--GELSAELKPDSDSRSEFVATCVNEVSGQVNNLSIEEFTMS 1879
E+ + +++ E + E G+ + + D F V E + ++E +++
Sbjct: 2607 EEESIREDVLEESLVTENVVGQQESVTEEIVDGEGSFTEDIVEEEESVTEEIVVDEESVT 2666
Query: 1878 RDRPEDAEIFKETVGTHQLEEKVGSTYAVPSGEKRDVNLILKE--VVTAANDSNLTEEKT 1705
++ ED E+ E + +E++ T + E +++E ++ D+ EK
Sbjct: 2667 KEIVEDEELVTEEI----VEDEGSFTEEIVEDEGSFTEEVIEERSLIEEVEDTETVAEKE 2722
Query: 1704 ISNTAHTADDVRKEMEVAIEERMQEKGVSYS-EKKAGTKSDTVGGR--VDEMSGQGSQLS 1534
+ D + E +EE EK V+ E+K K + R V+E +
Sbjct: 2723 EGSVIKEIIDEKSLTEKIVEE---EKSVTEEVEEKESVKEEVEEQRLVVEEEGSATEGIV 2779
Query: 1533 TKKLA---ISSDVAVDPKMFEKHASTDHLQEQISDTNEAAVDDKINPEDMMKKVDTAIND 1363
+LA I D+ V ++ E +TD EQ E +DD+ + + + + + + N+
Sbjct: 2780 EDRLATEGIVDDILVTEEIVEDGLATDEFVEQQGSIIEEVLDDEGSVTEEIVEEEGSPNE 2839
Query: 1362 AIFTEKKIISNIIQISDDENKSTGITAEENMLEKGKLNSEIKTDR--------------- 1228
I +I I + + E M+++G L +E+ D
Sbjct: 2840 EIVEGVSVIEEDDNIEPVSEEIVEGSVTEEMIKEG-LENEVILDEDSITEEALEKEGSVS 2898
Query: 1227 ----------TSEILAGRSDEERDQVSQFS-TEELLMCSGTVKDPNNFEKCSVSHR--RQ 1087
T EI+ D + + S +EE++ V++ E+ SV +
Sbjct: 2899 EEIVEEMGSLTEEIVDEERSTSEDMIEEGSASEEIIQEESQVEEV--VEEVSVIDEIVEE 2956
Query: 1086 EQIGHKNDNAVIE-NLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCTTEVRIA- 913
+++ K IE N + + + G+ ++E + + E++ TE +
Sbjct: 2957 DELDTKEVVEEIEFNTEEVVEHKEEEGSVAEEIVQEEKEGSVNEEIIEEVGSITEEMVEQ 3016
Query: 912 -----GELHEKRDLKSEFKANTTLE--------------TVGGCVNEKSRHVSQLSTEVL 790
E+ E+R + E + N +E V+E++ ++ E+L
Sbjct: 3017 DVSDNEEIVEERSVIEEAEENVWIEKEVEEEGLDNEEVIDEEDSVSEQAEEEVYINEEIL 3076
Query: 789 AMSSEMAEDAKVVG---------------------TDVVTYQLQEPSGDTNQVVVDEAVN 673
SS++ ED KV ++ Y ++E T +VVVDE N
Sbjct: 3077 KESSDV-EDVKVENELMNEEVNEETQSVAENNEEDKELDNYVVEETESVTEEVVVDEVPN 3135
Query: 672 KDEA---------AAKDCPPTGD-------------EKVGNIAYSLYEENIVKKETAIDE 559
E +D T D E+VG+ + + EE + +E E
Sbjct: 3136 SKEVQEIESIIEEIVEDGLTTDDLVGQQGSVIEEVVEEVGSDSEEIVEEASITEEVEKKE 3195
Query: 558 KMQEKWQLKADAASEIVA------RFVNEESGYARQLPTEKLAMSTDTVGD--YKISEKD 403
+ E ++ +I+ V EE + ++ TE+ +++ + V + E D
Sbjct: 3196 SVTEDILVEESVTGDILVEGSVTEEVVGEEKLVSEEIVTEEGSVAQEIVEEDAPATEEID 3255
Query: 402 IVSHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVESTSA 223
+ +++E + ++ V +E + +V +E + + E +E G+ E VE SA
Sbjct: 3256 EIESVTEEVVEEEGPVDEEIVQEEGSVT-EEIIQGESKVEEVVEEQGSENEEIFVEEVSA 3314
Query: 222 IAAGYARQLSTEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDTVNKD 43
+ TEE+ ++ + + + +++EQ +EVV E T + ++
Sbjct: 3315 SQEIVQNESGTEEILEKVSASQEI-VQDGSVTEQIIEEQKPVTEEVVNEEESITHEIIQE 3373
Query: 42 ET 37
E+
Sbjct: 3374 ES 3375
Score = 105 bits (262), Expect = 1e-19
Identities = 236/1181 (19%), Positives = 466/1181 (39%), Gaps = 49/1181 (4%)
Frame = -3
Query: 3402 QENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNKKCTAGSLLEKKDNVEVVIPSVK 3223
+E ++ V+ E S + +E+E +V D + GS+ EK + E+V V
Sbjct: 1074 KEEGSASEKVVKEEGSASEKIVEEEGSVTEEKKTMDEEIGDQGSVAEKVEEEELVTEEVI 1133
Query: 3222 VRKKR------DPASCSKTISSCKPRKASINKTN-------ENL---NMPSTQINKQELA 3091
R+ AS ++ + +P + K E L ++ Q++ +E+
Sbjct: 1134 EREGSINEDIVKEASITEEVEQIEPVTGKVEKIESITDEIKEQLVPEDIKEEQLDFEEIV 1193
Query: 3090 G--VIVLSDNSDDAAVSKGKVKEANTVIK------GATSSKKVKISSTGENSQERNSFAN 2935
V + + A++++ +E +V + G+T+ K VK SST +E+ S
Sbjct: 1194 AQRASVNDEKVEVASITEEVEEEEKSVSEEVLEEEGSTTEKVVKGSSTEVVVEEQGSVTE 1253
Query: 2934 DAALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQ---EESSGANDVAVNEKLKA 2764
+ L + ++ + E +KD+ ++++ EE G +NE +
Sbjct: 1254 NL-LEEESASQGIVEKEEFVDEEDSVKDQNVFEKEGSVTEQLVEEEKGL----INEDNEK 1308
Query: 2763 SDIEKGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATAINA 2584
++ + +K N + IKQQ G++ E ++ + S+ +
Sbjct: 1309 EELITEMSEEIKSVNEEIEETDLSTEEIIKQQ-----GLATYEFVEEEKSLTDKLLEEES 1363
Query: 2583 ATHLEKKNIGNT-LQALDVENKNVEVTIEGKIQGKAKRSESKTCSSEKKNIGNTLQALDE 2407
T K +G T L +V ++ V VT E E K+ S E G+ + + E
Sbjct: 1364 VT----KEVGETELSTQEVVDEKVSVTEE-------VIEEEKSVSEEVLEEGSATEEVVE 1412
Query: 2406 ENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGC----VNKASCEKF---NQSAKEFTMS 2248
E EV ++ + E + V C V K S + SA E +
Sbjct: 1413 EGSCTEVVVEEGSCTEVVVEEGSCTEVVVEEGSCTEIVVEKGSDTEIVVEEGSATEIVVE 1472
Query: 2247 TDVLKDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTEINVAVFTEKGSISN 2068
+ V E +E+GS S +++ ++ + VE+ + NV KG I N
Sbjct: 1473 EGSATEVVVEEGSATEEVVEEGSVSEEMLEEEGSATEEVVEEGLSSDNVQ--KSKGVIEN 1530
Query: 2067 TLHILEDINKKKEATNEEKLPEKGELSAELKPDSDSRSEFVATCVNEVSGQVNNLSIEEF 1888
I K E+ NE K+P + +S FV + G +N+S+E+
Sbjct: 1531 VGEIYSVKTAKDESMNE-KIPLE-------------KSSFVDDESFKGQGPTDNVSVEDV 1576
Query: 1887 TMSRDRPEDAEIFKETVGTHQLEEKVGSTYAVPSGE-KRDVNLILKEVVTAANDSNLTEE 1711
S D + +ET E + + GE + NLI +++ + EE
Sbjct: 1577 N-SEDIINEHTPLEETKIEELPTEYITTADIHTKGETETKYNLIYEKINEEVEKAKFQEE 1635
Query: 1710 KTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAGTKSDTVGGRVDEMSGQGSQLST 1531
K N + E E E+ +QE S +++ +SDT ++E ++L+
Sbjct: 1636 KITEN-------IPVERESVTEDIVQEP--SLAQEVEQKESDT--NEIEE-----TKLAN 1679
Query: 1530 KKLAISSDVAVDPKMFEKHA-STDHLQEQISDTNEAAVDDKINPEDMMKKVDTAINDAIF 1354
+K I +V+V + EK T+ + E+ E V+++++ + + + + + ++ I
Sbjct: 1680 EK--IIPEVSVTENVVEKEGLDTEEVLEEDESITEEIVEEEVSSSEEIVEEEESSSEEIV 1737
Query: 1353 TEKKIISNIIQISDDENKSTGITAEENMLEKGKLNSEIKTDRTSEILAGRSDEERDQVSQ 1174
E++ S I + ++E+ S I EE E ++ E S+E ++VS
Sbjct: 1738 EEEESSSEEI-VEEEESSSEEIVEEE----------ESSSEEIVEEEESSSEEIIEEVS- 1785
Query: 1173 FSTEELLMCSGTVKDPNNFEKCSVSHRRQEQIGHKNDNAVIENLQAYAVNNCDTGAKDGN 994
STEE+L ++G+
Sbjct: 1786 -STEEVL------------------------------------------------EEEGS 1796
Query: 993 FTEKENASKIVSSLHEDIKCTTEVRIAGELHEKRDLKSEFKANTTLETVGGCVNEKSRHV 814
TE+ + E++ T EV+ G + E+ LE G E
Sbjct: 1797 VTEE--------IVEEEVSTTEEVKDIGSVSEE-----------VLEEEGFGTEEFVGQQ 1837
Query: 813 SQLSTEVLAMSSEMAEDAKVVGTDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTG 634
+ E++ S + + VG++V ++ + G Q +V E V+ E + T
Sbjct: 1838 GSVIEEIVETESSTEKVLEDVGSNVE--EIVQEEGPVAQEIVHEEVSTTEKHDEVDRSTT 1895
Query: 633 DEKVGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVARFVNEESGYARQLPTEK 454
+E V + S+ EE IV++ +A +E ++E + E + V E ++ ++
Sbjct: 1896 EEIVEKVG-SVSEEIIVEEVSASEEIVEEGSVTEEVVEEEKLINEVGETESVTEEIVQKE 1954
Query: 453 LAMSTDTVG-----DYKISEKD-IVSHLSQEQIHDKDEVVDETIHATDTVNKDETAATDD 292
++ + + +G + +I EK+ IV + + +E+VD A + K+E T++
Sbjct: 1955 VSDAEEVLGQEGSMNEEILEKESIVEEIVGPEGSVTEEIVDHGSFAEEV--KEEELVTEE 2012
Query: 291 TLSEKEKENGNLKTECSVESTSAIAAGYARQL------STEELAMSTDIEEDYKISEKDI 130
+ + +K E S+ AI ++ +T+E+ ++ + ++E +
Sbjct: 2013 AVQYEGSVTEEIKEEESITENEAIEESAFAEIIEEKGPNTDEIVKEEGLDTEEIVNEVSV 2072
Query: 129 VSHLLQEQVHDKDEVVGETIHATDTVNKDETAATDDTLSEK 7
+++E+ +++VGE T+ + E +AT+D + E+
Sbjct: 2073 TDEVIEEEKLVNEQIVGEERSVTEKPVEVERSATEDLVEEE 2113
Score = 85.5 bits (210), Expect = 1e-13
Identities = 188/922 (20%), Positives = 378/922 (40%), Gaps = 80/922 (8%)
Frame = -3
Query: 2532 VENKNVEVTIEGKIQGKAKRSESKTCSSEKKNIGNTLQ--ALDEENKNVEVTIDRKIQGK 2359
VE K+V IE K + E + S E G ++ +DEE E+T+D KI K
Sbjct: 753 VEEKSV---IEEKNVSEEIPVEEENVSEEIPEGGIAIEDVPVDEETVTEEITVDEKIYDK 809
Query: 2358 -GKRSESKTGSIPVMVAGCVNKASCE------------KFNQSAKEFTMSTDVLKDAKVF 2218
E+ +PV + S E F + + +++ +++++ V
Sbjct: 810 LPNEIETVNEEMPVEDETLTEQISSEHERVPEEIIEEKPFTEGEETESLTDEIVEEGVVT 869
Query: 2217 ----EKDVATHQLEK------GSGSNDVVIDKNINAK------------VAVEKVDTEIN 2104
E+ + T ++++ G S + +I++ + + + EKV E
Sbjct: 870 DDIPEEQIITEKVQEEEEFVTGELSEEDIINEKVQEEDESVTEELPEEDIINEKVQEEEE 929
Query: 2103 VAV--FTEKGSISNTLHILEDIN---KKKEATNEEKLPEKGELSAELKPDSDSRSEFVAT 1939
A + GS++ + E +N + KE E+ P KG+L E P + EFV
Sbjct: 930 SAYQEIVQDGSVTKDVEYKELVNDDVRDKENFVIEEDPFKGQLINEGLPVEE---EFVTK 986
Query: 1938 CVNEVSGQV-NNLSIEEFTMSRDRP-EDAEIFKET----VGTHQLEEKVGST------YA 1795
+ V L+ E+ +++++ P E+ +FKE T ++ E+ GS
Sbjct: 987 ELPVKEESVFEELTEEDQSVTKEIPVEEHSVFKEVDEIESVTDEIVEEEGSVNEEVEEEV 1046
Query: 1794 VPSGEKRDVNLILKEVVTAANDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSY 1615
SGE + + +EV ++ L E+ + ++ V KE A E+ ++E+G
Sbjct: 1047 SVSGEVDETEYVTEEV----EETELVNEEVLKEEGSASEKVVKEEGSASEKIVEEEGSVT 1102
Query: 1614 SEKKAGTK----SDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEK-------HAS 1468
EKK + +V +V+E ++ ++ +I+ D+ + + E+
Sbjct: 1103 EEKKTMDEEIGDQGSVAEKVEEEELVTEEVIEREGSINEDIVKEASITEEVEQIEPVTGK 1162
Query: 1467 TDHLQEQISDTNEAAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGI 1288
+ ++ + E V + I E + + A ++ EK +++I + ++E KS
Sbjct: 1163 VEKIESITDEIKEQLVPEDIKEEQLDFEEIVAQRASVNDEKVEVASITEEVEEEEKS--- 1219
Query: 1287 TAEENMLEKGKLNSEIKTDRTSEILAGRS--------DEERDQVSQFSTEELLMCSGTVK 1132
+EE + E+G ++ ++E++ +EE EE + +VK
Sbjct: 1220 VSEEVLEEEGSTTEKVVKGSSTEVVVEEQGSVTENLLEEESASQGIVEKEEFVDEEDSVK 1279
Query: 1131 DPNNFEKCSVSHRRQEQIGHKNDNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSL 952
D N FEK EQ+ + + E+ K+ TE K V+
Sbjct: 1280 DQNVFEK---EGSVTEQLVEEEKGLINED-----------NEKEELITEMSEEIKSVNEE 1325
Query: 951 HEDIKCTTEVRIAGELHEKRDLKSEFKANTTL----ETVGGCVNEKSRHVSQLSTEVLAM 784
E+ +TE I + + E K+ T E+V V E ++ E +++
Sbjct: 1326 IEETDLSTEEIIKQQGLATYEFVEEEKSLTDKLLEEESVTKEVGETELSTQEVVDEKVSV 1385
Query: 783 SSEMAEDAKVVGTDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYS 604
+ E+ E+ K V +V+ E T +VV + + + C E+ G+
Sbjct: 1386 TEEVIEEEKSVSEEVL-----EEGSATEEVVEEGSCTEVVVEEGSCTEVVVEE-GSCTEV 1439
Query: 603 LYEENIVKKETAIDEKMQEKWQLKADAASEIVARFVNEESGYARQLPTEKLAMSTDTVGD 424
+ EE E +++ + ++ +A+EIV E G A ++ E+ + + + V +
Sbjct: 1440 VVEEGSC-TEIVVEKGSDTEIVVEEGSATEIVV-----EEGSATEVVVEEGSATEEVVEE 1493
Query: 423 YKISEKDIVSHLSQEQIHDKDEVVDETIHATDTVNKDETAATD--DTLSEKEKENGNLKT 250
+SE+ + +E+ +EVV+E + ++D V K + + + S K ++ ++
Sbjct: 1494 GSVSEE-----MLEEEGSATEEVVEEGL-SSDNVQKSKGVIENVGEIYSVKTAKDESMNE 1547
Query: 249 ECSVESTSAI-AAGYARQLSTEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKDEVVGET 73
+ +E +S + + Q T+ +++ ED ++ +DI++ + +E+ E
Sbjct: 1548 KIPLEKSSFVDDESFKGQGPTDNVSV-----ED--VNSEDIINEHTPLEETKIEELPTEY 1600
Query: 72 IHATDTVNKDETAATDDTLSEK 7
I D K ET + + EK
Sbjct: 1601 ITTADIHTKGETETKYNLIYEK 1622
Score = 80.1 bits (196), Expect = 6e-12
Identities = 165/789 (20%), Positives = 332/789 (42%), Gaps = 27/789 (3%)
Frame = -3
Query: 2286 EKFNQSAKEFTMSTDVLKDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTEI 2107
EK+N E T + ++ K+ +++ T Q E+G+ + + V +K +N E ++ EI
Sbjct: 598 EKYNIEDMEETEKENEIE--KIMDENKETEQTEEGN-TEEFVQEKELNQ----ETLENEI 650
Query: 2106 NVAVFTEKGSISNTLHILEDINKKKEATNEEKLPEKGELSAELKPDSDSRSEFVATCVNE 1927
V E+ N K++E+ EE E+ + + ++ EF+
Sbjct: 651 IVDHIKEEEDTRNV--------KEQESVLEESPIEELPVENNIGKINEEVEEFI------ 696
Query: 1926 VSGQVNNLSIEEFTMSRDRPEDAEIFKETVGTHQLEEKVGSTYAVPSGEKRDVNLILKEV 1747
+N + +EE + ++ P++ EI + V ++E + S + E ++
Sbjct: 697 ----LNEIPLEE-QVPKELPQE-EIEEIVVEELPIDEHLSSEETTVTEEDTFKGQLI--- 747
Query: 1746 VTAANDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAGTKSDTVGGRV 1567
N+ EEK++ + ++++ E E + E + E G++ + ++ T V
Sbjct: 748 ----NEEKPVEEKSVIEEKNVSEEIPVEEE-NVSEEIPEGGIAIEDVPVDEETVTEEITV 802
Query: 1566 DEMSGQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDTNEAAVDDK--INPEDM 1393
DE +L + ++ ++ V+ + + S++H E++ E +++K E+
Sbjct: 803 DEKIYD--KLPNEIETVNEEMPVEDETLTEQISSEH--ERVP---EEIIEEKPFTEGEET 855
Query: 1392 MKKVDTAINDAIFT----EKKIISNIIQISDDENKSTGITAEENML-EKGKLNSEIKTDR 1228
D + + + T E++II+ +Q ++E TG +EE+++ EK + E T+
Sbjct: 856 ESLTDEIVEEGVVTDDIPEEQIITEKVQ--EEEEFVTGELSEEDIINEKVQEEDESVTEE 913
Query: 1227 TSE--ILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKCSVSHRRQEQIGHKNDNAV 1054
E I+ + EE + Q E++ KD E + R +E N V
Sbjct: 914 LPEEDIINEKVQEEEESAYQ----EIVQDGSVTKDVEYKELVNDDVRDKE-------NFV 962
Query: 1053 IEN--LQAYAVNNCDTGAKDGNFTEKENASKIVSSLHE----DIKCTTEVRIAGELHEKR 892
IE + +N + + F KE K S E D T E+ + E H
Sbjct: 963 IEEDPFKGQLIN--EGLPVEEEFVTKELPVKEESVFEELTEEDQSVTKEIPV--EEH--- 1015
Query: 891 DLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDA----KVVGTDVVTYQL 724
S FK +E+V + E+ V++ E +++S E+ E +V T++V ++
Sbjct: 1016 ---SVFKEVDEIESVTDEIVEEEGSVNEEVEEEVSVSGEVDETEYVTEEVEETELVNEEV 1072
Query: 723 QEPSGDTNQVVV------DEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEENIVKKETAID 562
+ G ++ VV E + ++E + + T DE++G+ E + ++E +
Sbjct: 1073 LKEEGSASEKVVKEEGSASEKIVEEEGSVTEEKKTMDEEIGD--QGSVAEKVEEEELVTE 1130
Query: 561 EKMQEKWQLKADAASEIVARFVNEESGYARQLP--TEKLAMSTDTVGDYKISEKDIVSHL 388
E ++ + + D E + EE + EK+ TD +I E+ + +
Sbjct: 1131 EVIEREGSINEDIVKEAS---ITEEVEQIEPVTGKVEKIESITD-----EIKEQLVPEDI 1182
Query: 387 SQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVESTSAIAAGY 208
+EQ+ D +E+V + D K E A+ + + E+EK E +T + G
Sbjct: 1183 KEEQL-DFEEIVAQRASVND--EKVEVASITEEVEEEEKSVSEEVLEEEGSTTEKVVKGS 1239
Query: 207 ARQLSTEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDTVNKDETAAT 28
STE + +EE ++E + + + +K+E V E D ++ +
Sbjct: 1240 ----STEVV-----VEEQGSVTENLLEEESASQGIVEKEEFVDEEDSVKDQNVFEKEGSV 1290
Query: 27 DDTLSEKEK 1
+ L E+EK
Sbjct: 1291 TEQLVEEEK 1299
>ref|YP_006070601.1| hypothetical protein SALIVA_1456 [Streptococcus salivarius JIM8777]
gi|504447674|ref|WP_014634776.1| flagellar biosynthesis
protein FliS [Streptococcus salivarius]
gi|338745400|emb|CCB95766.1| hypothetical protein
SALIVA_1456 [Streptococcus salivarius JIM8777]
Length = 2835
Score = 129 bits (325), Expect = 7e-27
Identities = 213/1245 (17%), Positives = 507/1245 (40%), Gaps = 82/1245 (6%)
Frame = -3
Query: 3492 SRSRASYREKTGSVNQGVCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVIV 3313
S+SR+ +++ S + + ++S S E+ ++ + RS+++ + L E + V
Sbjct: 883 SQSRSESAKQSASTSLSLSTVASKSVSSSLSESLKTSQS--RSQSASTSASLSAEKSTSV 940
Query: 3312 NVVIGDNKKCTAGSLLEKKDNVEVVIPSVKVRKKRDPASCSKTISSCKPRKASINKTNEN 3133
+ + ++ K + + + + +VK S S S + + AS + +
Sbjct: 941 SSSLSESLKTSVSQ--SQSASTSASLSTVKSASVSSSLSESLKTSVSQSQSASTSASLST 998
Query: 3132 LNMPSTQINKQELAGVIVLSDNSDDAAVSKGKVKEANTVIKGATSSKKVKIS-----STG 2968
+ S + E V S +VS VK A+ V + S K +S ST
Sbjct: 999 VKSASVSSSLSESLKTSVSQSQSVSTSVSLSAVKSAS-VSSSLSESLKTSLSQSQFASTS 1057
Query: 2967 ENSQERNSFANDAALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQE------ES 2806
+ S + ++L+ L+ S + ++ A+ + L ++ S +S++S+ +S
Sbjct: 1058 ASLSTVKSESVSSSLSESLKTS--LSQSESASTSASLSAEKSASVSSSLSESLKTSVSQS 1115
Query: 2805 SGANDVAVNEKLKASDIEKGVDTTVKDA-NHTKKGNVSIMVGPIKQ---QKNVAKGISMN 2638
A+ A +K++ I + ++K + + ++ + S+ + +K ++++ S +
Sbjct: 1116 ESASTSASLSTVKSASISSSLSESLKTSVSQSESASTSVSLSTVKSASVSSSLSESASTS 1175
Query: 2637 EKMKGKGSVAKNATAINAATHLEKKNIGNTLQALDVEN--KNVEVTIEGKIQGKAKRSES 2464
+ SV+ + +A +A+ E +++ N+ A + + ++ V+ A SES
Sbjct: 1176 SSVSESQSVSNSESASESASVSESQSVSNSESASESASVSESQSVSNSESASESASVSES 1235
Query: 2463 KTCS-----------SEKKNIGNTLQALDEEN----KNVEVTIDRKIQGKGKRSESKTGS 2329
++ S SE +++ N+ A + E+ ++V + + S+S + S
Sbjct: 1236 QSASNSESASVSASISESQSVSNSESASESESVSESQSVSNSESASVSASISESQSVSNS 1295
Query: 2328 IPVMVAGCVNKASCEKFNQSAKEFTMSTDV--LKDAKVFEKDVATHQLEKGSGSNDVVID 2155
+ V+++ ++SA E ++ + +++ + + + + S S
Sbjct: 1296 ESASESASVSESQSVSNSESASESASVSESQSVSNSESASESASVSESQSVSNSESASES 1355
Query: 2154 KNINAKVAVEKVDTEINVAVFTEKGSISNTLHILED--INKKKEATNEEKLPEKGELSA- 1984
+I+A +V ++ A +E S+SN+ E +++ + +N E E +SA
Sbjct: 1356 ASISASQSVSNSESASESASVSESQSVSNSESASESASVSESQSVSNSESASESASISAS 1415
Query: 1983 ------ELKPDSDSRSEFVATCVNEVSGQVNNLSIEEFTMSRDRPEDAEIFKETVGTHQL 1822
E S S SE + +E + + ++S + + + ++ E+
Sbjct: 1416 QSVSNSESSSASSSVSESQSVSNSESASESASVSESQLVSNSESASESASVSESQSVSNS 1475
Query: 1821 EE-----KVGSTYAVPSGEKRDVNLILKEVVTAANDSNLTEEKTISNTAHTADDVRKEME 1657
E V + + + E V+ + E + +N + +E ++S + ++ +
Sbjct: 1476 ESASESASVSESQSASTSESASVSGSISESQSVSNSESASESSSVSESQSVSNSESASVS 1535
Query: 1656 VAIEERMQ---------EKGVSYSEKKAGTKSDTVGGRVDE-MSGQGSQLSTKKLAISSD 1507
++ E +S S+ + ++S + V E S S+ ++ +IS
Sbjct: 1536 ASVSESQSVSNSESASVSASISESQSVSNSESASESASVSESQSVSNSESASVSASISES 1595
Query: 1506 VAVDPKMFEKHASTDHLQEQISDTNEAAVDDKINPEDMMKKVDTAINDAIFTEKKIISNI 1327
+V +++ + +S++ A+V I+ + ++A A +E + +SN+
Sbjct: 1596 QSVSNSESASESASVSESQSVSNSESASVSASISESQSVSNSESASESASVSESQSVSNL 1655
Query: 1326 IQISDDENKSTGITAEENMLEKGKLNSEIKTDRTSEILAGRSDEERDQVSQFSTEELLMC 1147
S+ E+ S +E N + S ++ S + E + S E
Sbjct: 1656 ESASESESTSAS-QSESNSVSASVSESISESQSVSNSESASVSESVSESQSESNSESASV 1714
Query: 1146 SGTVKDP---NNFEKCSVSHRRQEQIGHKNDNAVIENL---QAYAVNNCDTGAKDGNFTE 985
S +V + +N E S S E N + E+ ++ + +N ++ + + +E
Sbjct: 1715 SESVSESQSVSNSESASESTSVSESQSVSNSESASESASVSESLSESNSESASVSASVSE 1774
Query: 984 KENASKIVS-SLHEDIKCTTEVRIAGELHEKRDLK-SEFKANTTLETVGGCVNEKSRHVS 811
++AS S S+ E I + V + S+ ++N+ +V ++E S+ VS
Sbjct: 1775 SQSASNSESASVSESISESQSVSNSESASVSESTSISQSESNSESASVSESISE-SQSVS 1833
Query: 810 QLSTEVLAMSSEMAEDAKVVGTDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGD 631
++E + S+ ++E ++ + + E ++ V E+ ++ + ++ +
Sbjct: 1834 --NSESASESASVSESQSASNSESAS--VSESISESQSVSNSESASESASVSESQSVSNS 1889
Query: 630 EKVGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVARFVNEESGYARQLPTEKL 451
E A ++ E+A + + Q +++ S V+ ++E + +
Sbjct: 1890 ESASESASISESQSASTSESASESASVSESQSASNSESASVSESISESQSVSNSESASES 1949
Query: 450 AMSTDTVGDYKISEKDIVSHLSQEQIHDKDEV--VDETIHATDTVNKDETAATDDTLSEK 277
A +++ + + +S+ Q E V E+I + + + E+A+ +++SE
Sbjct: 1950 ASVSESQSVSNSESASVSASVSESQSASTSESASVSESISESQSASNSESASVSESISES 2009
Query: 276 EKENGNLK-------TECSVESTSAIAAGYARQLSTEELAMSTDIEEDYKISEKDIVSHL 118
+ + + +E ESTS A+ A ++ ++ S E ISE VS+
Sbjct: 2010 QSVSTSESASESASVSESQSESTSESASESASVSESQSVSNSESASESASISESQSVSN- 2068
Query: 117 LQEQVHDKDEV-------VGETIHATDTVNKDETAATDDTLSEKE 4
E + V E+ + +V++ ++A+T ++ S E
Sbjct: 2069 -SESASESASVSESQSVSTSESASESASVSESQSASTSESTSVSE 2112
>ref|WP_000466197.1| hypothetical protein [Streptococcus mitis]
gi|339455648|gb|EGP68249.1| gram positive anchor
[Streptococcus mitis SK1080]
Length = 4327
Score = 128 bits (321), Expect = 2e-26
Identities = 242/1284 (18%), Positives = 494/1284 (38%), Gaps = 131/1284 (10%)
Frame = -3
Query: 3468 EKTGSVNQGVCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNK 3289
EK V ++S S++K+ +++ + V SE + + + + ++ + +
Sbjct: 2791 EKASEVASTSNSVSESASKVASEK-----ASEVASEKASTSNSVSESASKVASE------ 2839
Query: 3288 KCTAGSLLEKKDNVEVVIPSVKVRKKRDPASCSKTISSCKPRKAS-----INKTNENLNM 3124
A + ++V + V K + AS S ++S + AS + T+ +++
Sbjct: 2840 --KASEVASTSNSVSESVSKVASEKASEVASTSNSVSESASKVASEKASEVASTSNSVSE 2897
Query: 3123 PSTQINKQELAGVIVLSDNSDDAAVSKGKVKEANTV----------IKGATSSKKVKISS 2974
++++ E A + + NS +VSK ++A+ V + TS K +++S
Sbjct: 2898 SASKV-ASEKASEVASTSNSVSESVSKLTSEKASEVASTSNSVSESVSKLTSEKASEVAS 2956
Query: 2973 T------------GENSQERNSFANDAALNAKLQGSDKMKNTDVATENCVLKDKEKVSHT 2830
T E + E S +N + +A S+K +T N V + KV+
Sbjct: 2957 TSNSVSESASKLASEKASEVASTSNSVSESASKVASEKASEV-ASTSNSVSESASKVA-- 3013
Query: 2829 SNISQEESSGANDVAVNEKLKASDIEKGVDTTVKDANHT-------KKGNVSIMVGPIKQ 2671
S ++ E++S +N V+ + AS+ V +T + + K V+ + +
Sbjct: 3014 SEVASEKASTSNSVSESASKVASEKASEVASTSNSVSESASKVTSEKASEVASTSNSVSE 3073
Query: 2670 QKNVAKGISMNEKMKGKGSVAKNATAINAATHLE----KKNIGNTLQALDVENKNVEVTI 2503
+ +E SV+++A+ + + E ++ ++ L E + +
Sbjct: 3074 SASKVTSEKASEVASTSNSVSESASKVASEKASEVASTSNSVSESVSKLTSEKASEVASE 3133
Query: 2502 EGKIQGKAKRSESKTCSSEKKNIGNTLQALDEENKNV------EV-----TIDRKIQGKG 2356
S SK S + + +T ++ E V EV ++ +
Sbjct: 3134 VASTSNSVSESASKLASEKASEVASTSNSVSESASKVASEKASEVASTSNSVSESVSKLT 3193
Query: 2355 KRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDVLKDAKVFEKDVATHQLEKGSG 2176
S+ S V+ +K + EK ++ A + S V + A + A+ E S
Sbjct: 3194 SEKASEVASTSNSVSESASKVASEKASEVA---STSNSVSESASKVASEKAS---EVAST 3247
Query: 2175 SNDVVID-KNINAKVAVEKVDTEINVAVFTEKGSISNTLHILEDINKKKEATNEEKLPEK 1999
SN V + ++VA EK T +V+ K + + N E+ ++ +
Sbjct: 3248 SNSVSESASKVTSEVASEKASTSNSVSESASKVTSEKASEVASTSNSVSESVSKLTSEKA 3307
Query: 1998 GELSAELKPDSDSRSEFVATCVNEVSGQV------------------------NNLSIEE 1891
E+++E+ S+S SE V+ +E + +V + S+ E
Sbjct: 3308 SEVASEVASTSNSVSESVSKLTSEKASEVASTSNSVSESASKVASEKASEVASTSNSVSE 3367
Query: 1890 FTMSRDRPEDAEIFKETVGTHQ---------LEEKVGSTYAVPSGEKRDVNLILKEVVTA 1738
+ +E+ E T EK + + + + EV +
Sbjct: 3368 SVSKLTSEKASEVASEVASTSNSVSESASKVASEKASEVASTSNSVSESASKVASEVAST 3427
Query: 1737 AND-----SNLTEEKTISNTAHTADDVRKEMEVAIEERMQE-----KGVSYSEKK-AGTK 1591
+N S LT EK S A T++ V + E+ E VS S K A K
Sbjct: 3428 SNSVSESVSKLTSEKA-SEVASTSNSVSESASKVASEKASEVASTSNSVSESASKVASEK 3486
Query: 1590 SDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHAS---TDHLQEQISDTNEAAV 1420
+ V + +S S+++++K +S+VA + AS ++ E S +N +
Sbjct: 3487 ASEVASTSNSVSESASKVASEK---ASEVASTSNSVSESASKVASEKASEVASTSNSVSE 3543
Query: 1419 DDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGITAEENMLEKGKLN--- 1249
+ +V + N + K+ S + S+ ++S A E E +
Sbjct: 3544 SASKVASEKASEVASTSNSVSESASKVASEVASTSNSVSESASKLASEKASEVASTSNSV 3603
Query: 1248 ----SEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKCSVSHRRQEQ 1081
S++ +++ SE+ A S+ + S+ ++E+ + T + S + E
Sbjct: 3604 SESASKLASEKASEV-ASTSNSVSESASKVASEKASEVASTSNSVSESASKVASEKASEV 3662
Query: 1080 IGHKNDNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCTTE--VRIAGE 907
N+V E++ A A N + E+ASK+ S ++ T+ +
Sbjct: 3663 A--STSNSVSESVSKVASEKASEVASTSN-SVSESASKVASEKASEVASTSNSVSESVSK 3719
Query: 906 LHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSE-MAEDAKVVG--TDVV 736
L ++ + +N+ E+V +EK+ V+ S V + S+ M+E A V ++ V
Sbjct: 3720 LTSEKASEVASTSNSVSESVSKLTSEKASEVASTSNSVSELVSKLMSERASEVASTSNSV 3779
Query: 735 TYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDE------KVGNIAYSLYEENIVKKE 574
+ + + + V + + E+A+K E V A + E +
Sbjct: 3780 SESASKVASEKASEVASTSNSVSESASKVASEKASEVASTSNSVSESASKVTSEEASEVA 3839
Query: 573 TAIDEKMQEKWQLKADAASEIVARFVNEESGYARQLPTEKLAMSTDTVGDYKISEKDIVS 394
+ + + ++ ++ ASE VA N S A ++ +EK + T S + S
Sbjct: 3840 STSNSVSESASKVASEKASE-VASTSNSVSESASKVASEKASEVASTSNSVSESASKVTS 3898
Query: 393 HLSQE---QIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVESTSA 223
+ E ++ V E + + E A+T +++SE + + K S +++
Sbjct: 3899 EKASEKSSEVASTSNSVSELVSKLMSEKASEVASTSNSVSESASKLASEKASESASLSTS 3958
Query: 222 IAAGYAR--QLSTEELAMSTDIEE----DYKISEKDIVSHLLQEQVHDKDEVVGETIHA- 64
I+A + + S + + ST + + +S D VS + +K V T ++
Sbjct: 3959 ISASISASPKCSCVDDSTSTSVSKSASTSASVSTSDSVSESASKLASEKSSEVASTSNSV 4018
Query: 63 TDTVNK------DETAATDDTLSE 10
++ V+K E A+T +++SE
Sbjct: 4019 SELVSKLMSERASEVASTSNSVSE 4042
Score = 127 bits (320), Expect = 3e-26
Identities = 217/1184 (18%), Positives = 455/1184 (38%), Gaps = 40/1184 (3%)
Frame = -3
Query: 3441 VCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVI---VNVVIGDNKKCTAGS 3271
+ + +S+ ++ N+ +G ++ + ++ + N + V+ VI + +A +
Sbjct: 2658 IAAVKASNPEVANRIKSGDAGYSISPDGTVTITYKDGTQNTVKPPVSDVIYKSMSASAST 2717
Query: 3270 LLEKKDNVEVVIPSVKVRKKRDPASCSKTISSCKPRKASINKTNENLNMPSTQINKQELA 3091
+L +K + V K S S++ S KAS + N S E A
Sbjct: 2718 VLSEKAS------EVASEKASTSNSVSESASKVASEKASEVASTSNSVSESASKVASEKA 2771
Query: 3090 GVIVLSDNSDDAAVSKGKVKEANTVIKGAT----SSKKVKISSTGENSQERNSFANDAAL 2923
+ + NS +VSK ++A+ V + S+ KV E + E+ S +N +
Sbjct: 2772 SEVASTSNSVSESVSKVASEKASEVASTSNSVSESASKVASEKASEVASEKASTSNSVSE 2831
Query: 2922 NAKLQGSDKMKNTDVATENCVLKD-----KEKVSHTSNISQEESSGANDVAVNEKLKASD 2758
+A S+K +T N V + EK S ++ S S A+ VA + + +
Sbjct: 2832 SASKVASEKASEV-ASTSNSVSESVSKVASEKASEVASTSNSVSESASKVASEKASEVAS 2890
Query: 2757 IEKGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATAINAAT 2578
V + K V+ + + + +E SV+++ + + +
Sbjct: 2891 TSNSVSESASKVASEKASEVASTSNSVSESVSKLTSEKASEVASTSNSVSESVSKLTSEK 2950
Query: 2577 HLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSSEKKNIGNTLQALDEENK 2398
E + N++ + + + + S SK S + + +T ++ E
Sbjct: 2951 ASEVASTSNSVSESASKLASEKASEVASTSNSVSESASKVASEKASEVASTSNSVSESAS 3010
Query: 2397 NV-------EVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDV 2239
V + + + + S+ S + V++++ + ++ A E +++
Sbjct: 3011 KVASEVASEKASTSNSVSESASKVASEKASEVASTSNSVSESASKVTSEKASEVASTSNS 3070
Query: 2238 LKDAKVFEKDVATHQLEKGSGSNDVVID-KNINAKVAVEKVDTEINVAVFTEKGSISNTL 2062
+ ++ K + E S SN V + ++ A E T +V+ K +
Sbjct: 3071 VSESA--SKVTSEKASEVASTSNSVSESASKVASEKASEVASTSNSVSESVSKLTSEKAS 3128
Query: 2061 HILEDINKKKEATNEEKLPEKGELSAELKPDSDSRSEFVATCVNEVSGQV--NNLSIEEF 1888
+ ++ + +E E ++E+ S+S SE + +E + +V + S+ E
Sbjct: 3129 EVASEVASTSNSVSESASKLASEKASEVASTSNSVSESASKVASEKASEVASTSNSVSES 3188
Query: 1887 TMSRDRPEDAEIFKETVGTHQLEEKVGSTYAVPSGEKRDVNLILKEVVTAANDSNLTEEK 1708
+ +E+ + + KV S A S N + + A++
Sbjct: 3189 VSKLTSEKASEVASTSNSVSESASKVASEKA--SEVASTSNSVSESASKVASEKASEVAS 3246
Query: 1707 TISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKK-AGTKSDTVGGRVDEMSGQGSQLST 1531
T ++ + +A V EVA E+ VS S K K+ V + +S S+L++
Sbjct: 3247 TSNSVSESASKVTS--EVASEKASTSNSVSESASKVTSEKASEVASTSNSVSESVSKLTS 3304
Query: 1530 KKLA-ISSDVAVDPKMFEKHAS--TDHLQEQISDTNEAAVD--DKINPEDMMKKVDT--A 1372
+K + ++S+VA + S T +++ T+ + + K+ E + T +
Sbjct: 3305 EKASEVASEVASTSNSVSESVSKLTSEKASEVASTSNSVSESASKVASEKASEVASTSNS 3364
Query: 1371 INDAI--FTEKK---IISNIIQISDDENKSTGITAEENMLEKGKLNSEI--KTDRTSEIL 1213
+++++ T +K + S + S+ ++S A E E ++ + + + +
Sbjct: 3365 VSESVSKLTSEKASEVASEVASTSNSVSESASKVASEKASEVASTSNSVSESASKVASEV 3424
Query: 1212 AGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKCSVSHRRQEQIGHKNDNAVIENLQAY 1033
A S+ + VS+ ++E+ + T + S + E N+V E+
Sbjct: 3425 ASTSNSVSESVSKLTSEKASEVASTSNSVSESASKVASEKASEVA--STSNSVSESASKV 3482
Query: 1032 AVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCTTEVRIAGELHEKRDLKSEFKANTTLE 853
A A N + E+ASK+ S ++ T + + E + KA+
Sbjct: 3483 ASEKASEVASTSN-SVSESASKVASEKASEVAST-----SNSVSESASKVASEKASEVAS 3536
Query: 852 TVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVGTDVVTYQLQEPSGDTNQVVVDEAVN 673
T S+ S+ ++EV + S+ ++E A V ++V + T+ V + A
Sbjct: 3537 TSNSVSESASKVASEKASEVASTSNSVSESASKVASEVAS---------TSNSVSESASK 3587
Query: 672 KDEAAAKDCPPTGDEKVGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVARFVN 493
A + T + V A L E + + + + ++ ++ ASE VA N
Sbjct: 3588 LASEKASEVASTSN-SVSESASKLASEKASEVASTSNSVSESASKVASEKASE-VASTSN 3645
Query: 492 EESGYARQLPTEKLAMSTDTVGDYKISEKDIVSHLSQEQIHDKDEVVDETIHATDTVNKD 313
S A ++ +EK + T S + S + E + V E+ +
Sbjct: 3646 SVSESASKVASEKASEVASTSNSVSESVSKVASEKASE-VASTSNSVSESASKVASEKAS 3704
Query: 312 ETAATDDTLSEKEKENGNLKTECSVESTSAIAAGYARQLSTEELAMSTDIEEDYKISEKD 133
E A+T +++SE + + K V STS + +L++E+ + S +
Sbjct: 3705 EVASTSNSVSESVSKLTSEKAS-EVASTSNSVSESVSKLTSEKASEVASTSN----SVSE 3759
Query: 132 IVSHLLQE---QVHDKDEVVGETIHATDTVNKDETAATDDTLSE 10
+VS L+ E +V V E+ + E A+T +++SE
Sbjct: 3760 LVSKLMSERASEVASTSNSVSESASKVASEKASEVASTSNSVSE 3803
>ref|NP_001024204.1| Protein TTN-1, isoform g [Caenorhabditis elegans]
gi|373254512|emb|CCD72174.1| Protein TTN-1, isoform g
[Caenorhabditis elegans]
Length = 18562
Score = 125 bits (315), Expect = 1e-25
Identities = 259/1208 (21%), Positives = 474/1208 (39%), Gaps = 87/1208 (7%)
Frame = -3
Query: 3417 TKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNKKCTAGSLLEKKDNVEVV 3238
T E+QE + + +T ++ + VN + TA S + KKD+ +V
Sbjct: 9128 TAPESQETLNVEIAVTETTVQKITNPSDESAKKDVN-------EDTAVSSIVKKDDKDVN 9180
Query: 3237 IPSVK----VRKKRDPASCSKTISSCKPRKA--SINKTNENLNMPSTQINKQELAGVIVL 3076
S+ KK K I K KA SI++T+E L TQ + E
Sbjct: 9181 KKSLPESGLTTKKEIQGKPEKKIMKKKTEKADSSISETSETLTKDLTQTKQSEPEP---- 9236
Query: 3075 SDNSDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSFANDAALNAKLQGSD- 2899
+ + + +V ++ T K ++++ G S S +DA+ ++Q S+
Sbjct: 9237 AKRTTETSVQDEVKRKTETTSKSKQTTEEHP--QPGGKSDSSISSTSDASEVKQVQQSES 9294
Query: 2898 KMKNTDVATENCVLKDKEKVSHTSNISQEESSGANDVAVNEKLKASDIEKGVDTTVKDAN 2719
+ + E L+ K K+ T + ++E N V+EK K ++K + + +
Sbjct: 9295 EAQKVTEKPETAKLESKSKM--TEDTTKESD---NKETVDEKPKKKVLKKKTEKSDSTIS 9349
Query: 2718 HTKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATAINAATHLEKKNIGNTLQA 2539
T + + GP + + + +K K K I E+K+
Sbjct: 9350 ETSETSAVESAGPSESETQNVAAVDKEKKQKETDEKQKLEAEIAGKKSTEQKS------K 9403
Query: 2538 LDVENKNVEVTIEGKIQGKAKRSE--SKTCSSEKKNIGNTLQA-----LDEENKNVEVTI 2380
L+ E K E + + +++E SK ++EK + Q D K E+
Sbjct: 9404 LEAEAKLKRAAEEDAAKKQKEKTEAASKKAAAEKLELEKQAQINKAAEADAVKKQNELDE 9463
Query: 2379 DRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDVLKDAKVFEKDVAT 2200
K++ K + K + + S K Q+A+E D AK EK
Sbjct: 9464 QNKLEATKKLAAEKLK---------LEEQSAAKSKQAAEE-QAKLDAQTKAKAAEKQTGL 9513
Query: 2199 HQLEKG---SGSNDVVIDKNINA--KVAVEKVDTEINVAVFTEK-------GSISNTLHI 2056
+ EK SGSN+ V +K K EK D+ I+ T K S S T +
Sbjct: 9514 EKDEKSNKDSGSNETVEEKPKKKVLKKKTEKSDSSISQKSDTSKTVAESAGSSESETQKV 9573
Query: 2055 LEDINKKKEATNEEKLPEKGELSAELKPDSDSRSEFVATCVNEVSGQVNNLSIEEFTMSR 1876
+ +K+KE ++KL + E++A+ D S+ E + + +E +
Sbjct: 9574 ADATSKQKETDKKQKL--EAEITAKKSADEKSKLETESKLIKAAEDAAKKQKEKEDKLKL 9631
Query: 1875 DRPEDAEIFKETVGTHQLE-------EKVGSTYAVPSG-EKRDVNLILKEVVT--AANDS 1726
+ A++ + +LE +K AV E + + E T AA +
Sbjct: 9632 E----ADVASKKAAAEKLELEKQAQIKKAAEADAVKKQKELAEKQKLESEAATKKAAAEK 9687
Query: 1725 NLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAGTKSDTVGGRVDEMSGQG 1546
EE+ N A AD V+K+ E+ + +++ S +EK +++E S
Sbjct: 9688 LKLEEQAQINKAAEADAVKKQKELDEKNKLEANKKSAAEKL----------KLEEESAAK 9737
Query: 1545 SQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDT-NEAAVDDKINPEDMMKKV---D 1378
S+ + ++ A D K EK + + D+ ++ VD+K + + KK D
Sbjct: 9738 SKQTVEEQA-KLDAQTKEKTAEKQTGLEKDDKSTKDSESKETVDEKPKKKVLKKKTEKSD 9796
Query: 1377 TAINDAIFTEKKII-------SNIIQISDDENKS----------TGITAEENMLEKGKLN 1249
++I+ T K ++ S +++D K ITA+++ EK KL
Sbjct: 9797 SSISQKSVTSKTVVESGGPSESETQKVADAARKQKETDEKQKLEAEITAKKSADEKSKLE 9856
Query: 1248 SEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVK----DPNNFEKCSVSH--RRQ 1087
+E K + +E+ A + +E+D+ + TE + K +K + + +++
Sbjct: 9857 AESKLKKAAEVEAAKKQKEKDEQLKLDTEAASKKAAAEKLELEKQAQIKKAAEADAVKKE 9916
Query: 1086 EQIGHK---NDNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCTTEVRI 916
+++ K A + A + + KD E + E K + +
Sbjct: 9917 KELAEKQKLESEAATKKAAAEKLKLEEQKKKDAETASIEKQKEQEKLAQEQSKLEVDAKK 9976
Query: 915 AGELHEKRDLKSEFKANTTLETVGGCVNEK-SRHVSQLSTEVLAMS-SEMAEDAKVVG-- 748
+ EK+ L+SE K+ T E V+EK + V + TE S S+ ++ AK V
Sbjct: 9977 SA---EKQKLESETKSKKTEEAPKESVDEKPKKKVLKKKTEKSDSSISQKSDTAKTVAES 10033
Query: 747 ---TDVVTYQLQEPSGDTNQVVVDEAVN-KDEAAAKDCPPTGDEKVGNIAYSLYEENIVK 580
+D T ++ E Q DE + E AAK E+ + + +++
Sbjct: 10034 AGQSDSETQKVSEADKAHKQKESDEKQKLESEIAAK----KSAEQKSKLETEAKTKKVIE 10089
Query: 579 KETAIDEKMQEKWQLKADAASEIVARFVNE--ESGYARQLPTEKLAMSTDTVGDYKISEK 406
E+A +K QE + D+A + + + ES + PT + T + SE
Sbjct: 10090 DESAKKQKEQEDKKKGDDSAKKQKDQKEKQKLESEATSKKPTSEKQKDEKTPQEKAKSEN 10149
Query: 405 DIVSHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVESTS 226
+ V +Q+ K E + T+TV K+ ++T+ + K KE K + +
Sbjct: 10150 ETVMTTEPQQLEVKSE--PKKSDKTETVEKEVASSTEKSDDSKTKEPKEKKKIIKKKKDT 10207
Query: 225 AIAAGYARQLSTEELAMSTDIEEDYKIS-----EKDIVSHL----LQEQVHDK--DEVVG 79
+++LS++E + D+E D +S E D +S LQ++ + D +G
Sbjct: 10208 TKPQEASKELSSDESRI--DLESDISLSLDTVTESDDLSTASTIKLQKESDESGIDSRMG 10265
Query: 78 ETIHATDT 55
+T A D+
Sbjct: 10266 QTSEAEDS 10273
Score = 109 bits (272), Expect = 1e-20
Identities = 251/1195 (21%), Positives = 461/1195 (38%), Gaps = 124/1195 (10%)
Frame = -3
Query: 3237 IPSVKVRKKRDPASCSK--TISSCKPRKASINKTNENLNMPSTQINKQELAGVIVLSDNS 3064
+P K +K+D + K T + + +K ++++ + PS + NK E+ GV +
Sbjct: 12793 LPPAKKSEKKDEVTAEKQSTEALIESKKKEVDESKISEQQPSDK-NKSEVVGVPEKAAGP 12851
Query: 3063 DDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSFANDAALNAKLQGSDKMKNT 2884
+ +K V E V K T KK + S SQ+ N K DK K+
Sbjct: 12852 E----TKKDVSEIEEVPKKKTIKKKTE-KSDSSISQKSNVL--------KPADDDKSKSD 12898
Query: 2883 DVATENC-VLKDKEKVSHTSNISQEESSGAN---DVAVNEKLKASDIEKGVDTTVKDANH 2716
DV ++ +D+ KV+ S + + + + V++K K ++K T D+
Sbjct: 12899 DVTDKSKKTTEDQTKVATDSKLEKAADTTKQIETETVVDDKSKKKVLKK--KTEKSDSFI 12956
Query: 2715 TKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATAINAATHLEKKNIGNTLQAL 2536
++K +V P K ++ A+ I+ K K + V N + + K I + +
Sbjct: 12957 SQKSETPPVVEPTKPAESEAQKIAEVNKAKKQKEVDDN---LKREAEVAAKKIADEKLKI 13013
Query: 2535 DVENKNVEVTIEGKIQGKAKRSE----------SKTCSSEKKNIGNTLQALDEENKNVEV 2386
+ E N++ T E + K K + SK ++EK + Q + V
Sbjct: 13014 EAE-ANIKKTAEVEAAKKQKEKDEQLKLETEVVSKKSAAEKLELEKQAQIKKAAEADA-V 13071
Query: 2385 TIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDVLKDAKVFEKDV 2206
+++ K K +K + + + A +K ++ + +F K K EK V
Sbjct: 13072 KKQKELNEKNKLEAAKKSAADKLKLEEESAAKSKKVSEESVKFGEE----KKTKAGEKTV 13127
Query: 2205 ATHQLEKGSGSNDVVIDKNINA-------------KVAVEKVDTEINVAVFTE------- 2086
Q+E S + K++ A K EK D+ I+ T+
Sbjct: 13128 ---QVESEPTSKKTIDTKDVGATEPADETPKKKIIKKKTEKSDSSISQKSATDSEKVSKQ 13184
Query: 2085 -------KGSISNTLHILEDINKKKEATNEEKLPEKGELSAELKPDSDSRSEFVAT-CVN 1930
K ++S T + E KK+ +EKL E++A+ K ++D +S+ A +
Sbjct: 13185 KEQDEPTKPAVSETQMVTEADKSKKQKETDEKLKLDAEIAAKTKQEADEKSKLDAQEKIK 13244
Query: 1929 EVSGQVNNLSIEEFTMSRDRPEDAEIFKETVGTHQLEE-----KVGSTYAVPSGEKRDVN 1765
+VS +E + K + +LEE K A +++D
Sbjct: 13245 KVSEDDAARKEKELNDKLKLESEIATKKASADKLKLEEQAQAKKAAEVEAAKKQKEKDEQ 13304
Query: 1764 LILKEVVT----AANDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAG 1597
L L AA L ++ I A AD V+K+ E+ + +++ A
Sbjct: 13305 LKLDTEAASKKAAAEKLELEKQAQIKKAAG-ADAVKKQKELDEKNKLE----------AN 13353
Query: 1596 TKSDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDT-NEAAV 1420
KS +++E S S+ + ++ A D K EK + ++ ++ ++ V
Sbjct: 13354 KKSAAGKLKIEEESAAKSKQTVEEQA-KLDAQTKAKTAEKQTKLEKDEKSTKESESKETV 13412
Query: 1419 DDKINPEDMMKKV---DTAINDAIFTEKKII-------SNIIQISDDENKS--------- 1297
D+K + + KK D++I+ T K ++ S +++D K
Sbjct: 13413 DEKPKKKVLKKKTEKSDSSISQKSETSKTVVESAGPSESETQKVADAARKQKETDEKQKL 13472
Query: 1296 -TGITAEENMLEKGKLNSEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNN 1120
ITA+++ EK KL +E K + +E+ A + +E+D+ + TE + K
Sbjct: 13473 EAEITAKKSADEKSKLEAESKLKKAAEVEAAKKQKEKDEQLKLDTEAASKKAAAEK--LE 13530
Query: 1119 FEKCSVSHRRQEQIGHKNDNAVIE--NLQAYAVNNCDTGAKDGNFTEKENASKI--VSSL 952
EK S + E K + E L++ A K +K+ A++I +
Sbjct: 13531 LEKQSHIKKAAEVDAVKKQKELEEKQRLESEAATKKADAEKLKLEEQKKKAAEIALIEIQ 13590
Query: 951 HEDIKCTTE-VRIAGELH---EKRDLKSEFKANTTLETVGGCVNEKSR------------ 820
E K E R+ E EK+ L+SE K+ T E V+EK +
Sbjct: 13591 KEQEKLAQEQSRLEDEAKKSAEKQKLESETKSKQTEEAPKESVDEKPKKKVLKKKTEKSD 13650
Query: 819 ----HVSQLSTEVLAMSSEMAEDAKVVGTDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAK 652
S+ + + + + D +V V Q P T+ + + K E +K
Sbjct: 13651 SSISQKSKSAKSTVDAAETLESDFNLVEKKTVQKVEQSPDESTSATIKRDPAQKTEEISK 13710
Query: 651 DCPPTGDEK---VGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVARFVNEESG 481
GDEK + K+ + +K Q+ + +DA+ V++ ++
Sbjct: 13711 Q--DDGDEKKTTTDGKPPKPEDSEATPKKRVVKKKTQKSDSVASDASLADVSKLSDD--- 13765
Query: 480 YARQLPTEKLAMSTDTVGDYKISEKDIVSHLSQEQIHDKDEVVDETI----HATDT---- 325
+ P +K+ D ISE V + E + E ++ I +TD+
Sbjct: 13766 -VEEKPKKKVLKKKTEKSDSVISETSSVDTIKPESVEIPTEKAEQMILHNRFSTDSAVES 13824
Query: 324 ----VNKDETAATDDTLSEKEKENGNLK-TECSVESTSAI-------AAGYARQLSTEEL 181
+KD+T T D + + K + E S+ S ++ G+A + +++ L
Sbjct: 13825 EPKNAHKDDTEKTTDDMMTRRKSSAIFSDDEQSISSKTSSEGRRRRRRTGFASKFASDTL 13884
Query: 180 AMSTD-IE-EDYKISEKDIVSHLLQEQVHDKDEVVGETIHA-TDTVNKDETAATD 25
A+ D +E E ++E D V+ + + D + E H T+ DE TD
Sbjct: 13885 ALRGDNVEIEAELLAEDDTVTWKVNGKDADLNSRCHEMSHTFFRTLIIDEVEPTD 13939
>ref|NP_001024201.1| Protein TTN-1, isoform d [Caenorhabditis elegans]
gi|24620455|gb|AAN61519.1| 1MDa_1 protein [Caenorhabditis
elegans] gi|373254509|emb|CCD72171.1| Protein TTN-1,
isoform d [Caenorhabditis elegans]
Length = 10578
Score = 125 bits (315), Expect = 1e-25
Identities = 259/1208 (21%), Positives = 474/1208 (39%), Gaps = 87/1208 (7%)
Frame = -3
Query: 3417 TKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNKKCTAGSLLEKKDNVEVV 3238
T E+QE + + +T ++ + VN + TA S + KKD+ +V
Sbjct: 9108 TAPESQETLNVEIAVTETTVQKITNPSDESAKKDVN-------EDTAVSSIVKKDDKDVN 9160
Query: 3237 IPSVK----VRKKRDPASCSKTISSCKPRKA--SINKTNENLNMPSTQINKQELAGVIVL 3076
S+ KK K I K KA SI++T+E L TQ + E
Sbjct: 9161 KKSLPESGLTTKKEIQGKPEKKIMKKKTEKADSSISETSETLTKDLTQTKQSEPEP---- 9216
Query: 3075 SDNSDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSFANDAALNAKLQGSD- 2899
+ + + +V ++ T K ++++ G S S +DA+ ++Q S+
Sbjct: 9217 AKRTTETSVQDEVKRKTETTSKSKQTTEEHP--QPGGKSDSSISSTSDASEVKQVQQSES 9274
Query: 2898 KMKNTDVATENCVLKDKEKVSHTSNISQEESSGANDVAVNEKLKASDIEKGVDTTVKDAN 2719
+ + E L+ K K+ T + ++E N V+EK K ++K + + +
Sbjct: 9275 EAQKVTEKPETAKLESKSKM--TEDTTKESD---NKETVDEKPKKKVLKKKTEKSDSTIS 9329
Query: 2718 HTKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATAINAATHLEKKNIGNTLQA 2539
T + + GP + + + +K K K I E+K+
Sbjct: 9330 ETSETSAVESAGPSESETQNVAAVDKEKKQKETDEKQKLEAEIAGKKSTEQKS------K 9383
Query: 2538 LDVENKNVEVTIEGKIQGKAKRSE--SKTCSSEKKNIGNTLQA-----LDEENKNVEVTI 2380
L+ E K E + + +++E SK ++EK + Q D K E+
Sbjct: 9384 LEAEAKLKRAAEEDAAKKQKEKTEAASKKAAAEKLELEKQAQINKAAEADAVKKQNELDE 9443
Query: 2379 DRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDVLKDAKVFEKDVAT 2200
K++ K + K + + S K Q+A+E D AK EK
Sbjct: 9444 QNKLEATKKLAAEKLK---------LEEQSAAKSKQAAEE-QAKLDAQTKAKAAEKQTGL 9493
Query: 2199 HQLEKG---SGSNDVVIDKNINA--KVAVEKVDTEINVAVFTEK-------GSISNTLHI 2056
+ EK SGSN+ V +K K EK D+ I+ T K S S T +
Sbjct: 9494 EKDEKSNKDSGSNETVEEKPKKKVLKKKTEKSDSSISQKSDTSKTVAESAGSSESETQKV 9553
Query: 2055 LEDINKKKEATNEEKLPEKGELSAELKPDSDSRSEFVATCVNEVSGQVNNLSIEEFTMSR 1876
+ +K+KE ++KL + E++A+ D S+ E + + +E +
Sbjct: 9554 ADATSKQKETDKKQKL--EAEITAKKSADEKSKLETESKLIKAAEDAAKKQKEKEDKLKL 9611
Query: 1875 DRPEDAEIFKETVGTHQLE-------EKVGSTYAVPSG-EKRDVNLILKEVVT--AANDS 1726
+ A++ + +LE +K AV E + + E T AA +
Sbjct: 9612 E----ADVASKKAAAEKLELEKQAQIKKAAEADAVKKQKELAEKQKLESEAATKKAAAEK 9667
Query: 1725 NLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAGTKSDTVGGRVDEMSGQG 1546
EE+ N A AD V+K+ E+ + +++ S +EK +++E S
Sbjct: 9668 LKLEEQAQINKAAEADAVKKQKELDEKNKLEANKKSAAEKL----------KLEEESAAK 9717
Query: 1545 SQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDT-NEAAVDDKINPEDMMKKV---D 1378
S+ + ++ A D K EK + + D+ ++ VD+K + + KK D
Sbjct: 9718 SKQTVEEQA-KLDAQTKEKTAEKQTGLEKDDKSTKDSESKETVDEKPKKKVLKKKTEKSD 9776
Query: 1377 TAINDAIFTEKKII-------SNIIQISDDENKS----------TGITAEENMLEKGKLN 1249
++I+ T K ++ S +++D K ITA+++ EK KL
Sbjct: 9777 SSISQKSVTSKTVVESGGPSESETQKVADAARKQKETDEKQKLEAEITAKKSADEKSKLE 9836
Query: 1248 SEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVK----DPNNFEKCSVSH--RRQ 1087
+E K + +E+ A + +E+D+ + TE + K +K + + +++
Sbjct: 9837 AESKLKKAAEVEAAKKQKEKDEQLKLDTEAASKKAAAEKLELEKQAQIKKAAEADAVKKE 9896
Query: 1086 EQIGHK---NDNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCTTEVRI 916
+++ K A + A + + KD E + E K + +
Sbjct: 9897 KELAEKQKLESEAATKKAAAEKLKLEEQKKKDAETASIEKQKEQEKLAQEQSKLEVDAKK 9956
Query: 915 AGELHEKRDLKSEFKANTTLETVGGCVNEK-SRHVSQLSTEVLAMS-SEMAEDAKVVG-- 748
+ EK+ L+SE K+ T E V+EK + V + TE S S+ ++ AK V
Sbjct: 9957 SA---EKQKLESETKSKKTEEAPKESVDEKPKKKVLKKKTEKSDSSISQKSDTAKTVAES 10013
Query: 747 ---TDVVTYQLQEPSGDTNQVVVDEAVN-KDEAAAKDCPPTGDEKVGNIAYSLYEENIVK 580
+D T ++ E Q DE + E AAK E+ + + +++
Sbjct: 10014 AGQSDSETQKVSEADKAHKQKESDEKQKLESEIAAK----KSAEQKSKLETEAKTKKVIE 10069
Query: 579 KETAIDEKMQEKWQLKADAASEIVARFVNE--ESGYARQLPTEKLAMSTDTVGDYKISEK 406
E+A +K QE + D+A + + + ES + PT + T + SE
Sbjct: 10070 DESAKKQKEQEDKKKGDDSAKKQKDQKEKQKLESEATSKKPTSEKQKDEKTPQEKAKSEN 10129
Query: 405 DIVSHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVESTS 226
+ V +Q+ K E + T+TV K+ ++T+ + K KE K + +
Sbjct: 10130 ETVMTTEPQQLEVKSE--PKKSDKTETVEKEVASSTEKSDDSKTKEPKEKKKIIKKKKDT 10187
Query: 225 AIAAGYARQLSTEELAMSTDIEEDYKIS-----EKDIVSHL----LQEQVHDK--DEVVG 79
+++LS++E + D+E D +S E D +S LQ++ + D +G
Sbjct: 10188 TKPQEASKELSSDESRI--DLESDISLSLDTVTESDDLSTASTIKLQKESDESGIDSRMG 10245
Query: 78 ETIHATDT 55
+T A D+
Sbjct: 10246 QTSEAEDS 10253
>ref|NP_001024203.1| Protein TTN-1, isoform f [Caenorhabditis elegans]
gi|24620454|gb|AAN61518.1| 2MDa_2 protein [Caenorhabditis
elegans] gi|373254511|emb|CCD72173.1| Protein TTN-1,
isoform f [Caenorhabditis elegans]
Length = 18519
Score = 125 bits (315), Expect = 1e-25
Identities = 259/1208 (21%), Positives = 474/1208 (39%), Gaps = 87/1208 (7%)
Frame = -3
Query: 3417 TKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNKKCTAGSLLEKKDNVEVV 3238
T E+QE + + +T ++ + VN + TA S + KKD+ +V
Sbjct: 9128 TAPESQETLNVEIAVTETTVQKITNPSDESAKKDVN-------EDTAVSSIVKKDDKDVN 9180
Query: 3237 IPSVK----VRKKRDPASCSKTISSCKPRKA--SINKTNENLNMPSTQINKQELAGVIVL 3076
S+ KK K I K KA SI++T+E L TQ + E
Sbjct: 9181 KKSLPESGLTTKKEIQGKPEKKIMKKKTEKADSSISETSETLTKDLTQTKQSEPEP---- 9236
Query: 3075 SDNSDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSFANDAALNAKLQGSD- 2899
+ + + +V ++ T K ++++ G S S +DA+ ++Q S+
Sbjct: 9237 AKRTTETSVQDEVKRKTETTSKSKQTTEEHP--QPGGKSDSSISSTSDASEVKQVQQSES 9294
Query: 2898 KMKNTDVATENCVLKDKEKVSHTSNISQEESSGANDVAVNEKLKASDIEKGVDTTVKDAN 2719
+ + E L+ K K+ T + ++E N V+EK K ++K + + +
Sbjct: 9295 EAQKVTEKPETAKLESKSKM--TEDTTKESD---NKETVDEKPKKKVLKKKTEKSDSTIS 9349
Query: 2718 HTKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATAINAATHLEKKNIGNTLQA 2539
T + + GP + + + +K K K I E+K+
Sbjct: 9350 ETSETSAVESAGPSESETQNVAAVDKEKKQKETDEKQKLEAEIAGKKSTEQKS------K 9403
Query: 2538 LDVENKNVEVTIEGKIQGKAKRSE--SKTCSSEKKNIGNTLQA-----LDEENKNVEVTI 2380
L+ E K E + + +++E SK ++EK + Q D K E+
Sbjct: 9404 LEAEAKLKRAAEEDAAKKQKEKTEAASKKAAAEKLELEKQAQINKAAEADAVKKQNELDE 9463
Query: 2379 DRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDVLKDAKVFEKDVAT 2200
K++ K + K + + S K Q+A+E D AK EK
Sbjct: 9464 QNKLEATKKLAAEKLK---------LEEQSAAKSKQAAEE-QAKLDAQTKAKAAEKQTGL 9513
Query: 2199 HQLEKG---SGSNDVVIDKNINA--KVAVEKVDTEINVAVFTEK-------GSISNTLHI 2056
+ EK SGSN+ V +K K EK D+ I+ T K S S T +
Sbjct: 9514 EKDEKSNKDSGSNETVEEKPKKKVLKKKTEKSDSSISQKSDTSKTVAESAGSSESETQKV 9573
Query: 2055 LEDINKKKEATNEEKLPEKGELSAELKPDSDSRSEFVATCVNEVSGQVNNLSIEEFTMSR 1876
+ +K+KE ++KL + E++A+ D S+ E + + +E +
Sbjct: 9574 ADATSKQKETDKKQKL--EAEITAKKSADEKSKLETESKLIKAAEDAAKKQKEKEDKLKL 9631
Query: 1875 DRPEDAEIFKETVGTHQLE-------EKVGSTYAVPSG-EKRDVNLILKEVVT--AANDS 1726
+ A++ + +LE +K AV E + + E T AA +
Sbjct: 9632 E----ADVASKKAAAEKLELEKQAQIKKAAEADAVKKQKELAEKQKLESEAATKKAAAEK 9687
Query: 1725 NLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAGTKSDTVGGRVDEMSGQG 1546
EE+ N A AD V+K+ E+ + +++ S +EK +++E S
Sbjct: 9688 LKLEEQAQINKAAEADAVKKQKELDEKNKLEANKKSAAEKL----------KLEEESAAK 9737
Query: 1545 SQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDT-NEAAVDDKINPEDMMKKV---D 1378
S+ + ++ A D K EK + + D+ ++ VD+K + + KK D
Sbjct: 9738 SKQTVEEQA-KLDAQTKEKTAEKQTGLEKDDKSTKDSESKETVDEKPKKKVLKKKTEKSD 9796
Query: 1377 TAINDAIFTEKKII-------SNIIQISDDENKS----------TGITAEENMLEKGKLN 1249
++I+ T K ++ S +++D K ITA+++ EK KL
Sbjct: 9797 SSISQKSVTSKTVVESGGPSESETQKVADAARKQKETDEKQKLEAEITAKKSADEKSKLE 9856
Query: 1248 SEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVK----DPNNFEKCSVSH--RRQ 1087
+E K + +E+ A + +E+D+ + TE + K +K + + +++
Sbjct: 9857 AESKLKKAAEVEAAKKQKEKDEQLKLDTEAASKKAAAEKLELEKQAQIKKAAEADAVKKE 9916
Query: 1086 EQIGHK---NDNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCTTEVRI 916
+++ K A + A + + KD E + E K + +
Sbjct: 9917 KELAEKQKLESEAATKKAAAEKLKLEEQKKKDAETASIEKQKEQEKLAQEQSKLEVDAKK 9976
Query: 915 AGELHEKRDLKSEFKANTTLETVGGCVNEK-SRHVSQLSTEVLAMS-SEMAEDAKVVG-- 748
+ EK+ L+SE K+ T E V+EK + V + TE S S+ ++ AK V
Sbjct: 9977 SA---EKQKLESETKSKKTEEAPKESVDEKPKKKVLKKKTEKSDSSISQKSDTAKTVAES 10033
Query: 747 ---TDVVTYQLQEPSGDTNQVVVDEAVN-KDEAAAKDCPPTGDEKVGNIAYSLYEENIVK 580
+D T ++ E Q DE + E AAK E+ + + +++
Sbjct: 10034 AGQSDSETQKVSEADKAHKQKESDEKQKLESEIAAK----KSAEQKSKLETEAKTKKVIE 10089
Query: 579 KETAIDEKMQEKWQLKADAASEIVARFVNE--ESGYARQLPTEKLAMSTDTVGDYKISEK 406
E+A +K QE + D+A + + + ES + PT + T + SE
Sbjct: 10090 DESAKKQKEQEDKKKGDDSAKKQKDQKEKQKLESEATSKKPTSEKQKDEKTPQEKAKSEN 10149
Query: 405 DIVSHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVESTS 226
+ V +Q+ K E + T+TV K+ ++T+ + K KE K + +
Sbjct: 10150 ETVMTTEPQQLEVKSE--PKKSDKTETVEKEVASSTEKSDDSKTKEPKEKKKIIKKKKDT 10207
Query: 225 AIAAGYARQLSTEELAMSTDIEEDYKIS-----EKDIVSHL----LQEQVHDK--DEVVG 79
+++LS++E + D+E D +S E D +S LQ++ + D +G
Sbjct: 10208 TKPQEASKELSSDESRI--DLESDISLSLDTVTESDDLSTASTIKLQKESDESGIDSRMG 10265
Query: 78 ETIHATDT 55
+T A D+
Sbjct: 10266 QTSEAEDS 10273
Score = 109 bits (272), Expect = 1e-20
Identities = 251/1195 (21%), Positives = 461/1195 (38%), Gaps = 124/1195 (10%)
Frame = -3
Query: 3237 IPSVKVRKKRDPASCSK--TISSCKPRKASINKTNENLNMPSTQINKQELAGVIVLSDNS 3064
+P K +K+D + K T + + +K ++++ + PS + NK E+ GV +
Sbjct: 12793 LPPAKKSEKKDEVTAEKQSTEALIESKKKEVDESKISEQQPSDK-NKSEVVGVPEKAAGP 12851
Query: 3063 DDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSFANDAALNAKLQGSDKMKNT 2884
+ +K V E V K T KK + S SQ+ N K DK K+
Sbjct: 12852 E----TKKDVSEIEEVPKKKTIKKKTE-KSDSSISQKSNVL--------KPADDDKSKSD 12898
Query: 2883 DVATENC-VLKDKEKVSHTSNISQEESSGAN---DVAVNEKLKASDIEKGVDTTVKDANH 2716
DV ++ +D+ KV+ S + + + + V++K K ++K T D+
Sbjct: 12899 DVTDKSKKTTEDQTKVATDSKLEKAADTTKQIETETVVDDKSKKKVLKK--KTEKSDSFI 12956
Query: 2715 TKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATAINAATHLEKKNIGNTLQAL 2536
++K +V P K ++ A+ I+ K K + V N + + K I + +
Sbjct: 12957 SQKSETPPVVEPTKPAESEAQKIAEVNKAKKQKEVDDN---LKREAEVAAKKIADEKLKI 13013
Query: 2535 DVENKNVEVTIEGKIQGKAKRSE----------SKTCSSEKKNIGNTLQALDEENKNVEV 2386
+ E N++ T E + K K + SK ++EK + Q + V
Sbjct: 13014 EAE-ANIKKTAEVEAAKKQKEKDEQLKLETEVVSKKSAAEKLELEKQAQIKKAAEADA-V 13071
Query: 2385 TIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDVLKDAKVFEKDV 2206
+++ K K +K + + + A +K ++ + +F K K EK V
Sbjct: 13072 KKQKELNEKNKLEAAKKSAADKLKLEEESAAKSKKVSEESVKFGEE----KKTKAGEKTV 13127
Query: 2205 ATHQLEKGSGSNDVVIDKNINA-------------KVAVEKVDTEINVAVFTE------- 2086
Q+E S + K++ A K EK D+ I+ T+
Sbjct: 13128 ---QVESEPTSKKTIDTKDVGATEPADETPKKKIIKKKTEKSDSSISQKSATDSEKVSKQ 13184
Query: 2085 -------KGSISNTLHILEDINKKKEATNEEKLPEKGELSAELKPDSDSRSEFVAT-CVN 1930
K ++S T + E KK+ +EKL E++A+ K ++D +S+ A +
Sbjct: 13185 KEQDEPTKPAVSETQMVTEADKSKKQKETDEKLKLDAEIAAKTKQEADEKSKLDAQEKIK 13244
Query: 1929 EVSGQVNNLSIEEFTMSRDRPEDAEIFKETVGTHQLEE-----KVGSTYAVPSGEKRDVN 1765
+VS +E + K + +LEE K A +++D
Sbjct: 13245 KVSEDDAARKEKELNDKLKLESEIATKKASADKLKLEEQAQAKKAAEVEAAKKQKEKDEQ 13304
Query: 1764 LILKEVVT----AANDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAG 1597
L L AA L ++ I A AD V+K+ E+ + +++ A
Sbjct: 13305 LKLDTEAASKKAAAEKLELEKQAQIKKAAG-ADAVKKQKELDEKNKLE----------AN 13353
Query: 1596 TKSDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDT-NEAAV 1420
KS +++E S S+ + ++ A D K EK + ++ ++ ++ V
Sbjct: 13354 KKSAAGKLKIEEESAAKSKQTVEEQA-KLDAQTKAKTAEKQTKLEKDEKSTKESESKETV 13412
Query: 1419 DDKINPEDMMKKV---DTAINDAIFTEKKII-------SNIIQISDDENKS--------- 1297
D+K + + KK D++I+ T K ++ S +++D K
Sbjct: 13413 DEKPKKKVLKKKTEKSDSSISQKSETSKTVVESAGPSESETQKVADAARKQKETDEKQKL 13472
Query: 1296 -TGITAEENMLEKGKLNSEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNN 1120
ITA+++ EK KL +E K + +E+ A + +E+D+ + TE + K
Sbjct: 13473 EAEITAKKSADEKSKLEAESKLKKAAEVEAAKKQKEKDEQLKLDTEAASKKAAAEK--LE 13530
Query: 1119 FEKCSVSHRRQEQIGHKNDNAVIE--NLQAYAVNNCDTGAKDGNFTEKENASKI--VSSL 952
EK S + E K + E L++ A K +K+ A++I +
Sbjct: 13531 LEKQSHIKKAAEVDAVKKQKELEEKQRLESEAATKKADAEKLKLEEQKKKAAEIALIEIQ 13590
Query: 951 HEDIKCTTE-VRIAGELH---EKRDLKSEFKANTTLETVGGCVNEKSR------------ 820
E K E R+ E EK+ L+SE K+ T E V+EK +
Sbjct: 13591 KEQEKLAQEQSRLEDEAKKSAEKQKLESETKSKQTEEAPKESVDEKPKKKVLKKKTEKSD 13650
Query: 819 ----HVSQLSTEVLAMSSEMAEDAKVVGTDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAK 652
S+ + + + + D +V V Q P T+ + + K E +K
Sbjct: 13651 SSISQKSKSAKSTVDAAETLESDFNLVEKKTVQKVEQSPDESTSATIKRDPAQKTEEISK 13710
Query: 651 DCPPTGDEK---VGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVARFVNEESG 481
GDEK + K+ + +K Q+ + +DA+ V++ ++
Sbjct: 13711 Q--DDGDEKKTTTDGKPPKPEDSEATPKKRVVKKKTQKSDSVASDASLADVSKLSDD--- 13765
Query: 480 YARQLPTEKLAMSTDTVGDYKISEKDIVSHLSQEQIHDKDEVVDETI----HATDT---- 325
+ P +K+ D ISE V + E + E ++ I +TD+
Sbjct: 13766 -VEEKPKKKVLKKKTEKSDSVISETSSVDTIKPESVEIPTEKAEQMILHNRFSTDSAVES 13824
Query: 324 ----VNKDETAATDDTLSEKEKENGNLK-TECSVESTSAI-------AAGYARQLSTEEL 181
+KD+T T D + + K + E S+ S ++ G+A + +++ L
Sbjct: 13825 EPKNAHKDDTEKTTDDMMTRRKSSAIFSDDEQSISSKTSSEGRRRRRRTGFASKFASDTL 13884
Query: 180 AMSTD-IE-EDYKISEKDIVSHLLQEQVHDKDEVVGETIHA-TDTVNKDETAATD 25
A+ D +E E ++E D V+ + + D + E H T+ DE TD
Sbjct: 13885 ALRGDNVEIEAELLAEDDTVTWKVNGKDADLNSRCHEMSHTFFRTLIIDEVEPTD 13939
>ref|NP_001024202.1| Protein TTN-1, isoform e [Caenorhabditis elegans]
gi|24620453|gb|AAN61517.1| 2MDa_1 protein [Caenorhabditis
elegans] gi|373254510|emb|CCD72172.1| Protein TTN-1,
isoform e [Caenorhabditis elegans]
Length = 18534
Score = 125 bits (315), Expect = 1e-25
Identities = 259/1208 (21%), Positives = 474/1208 (39%), Gaps = 87/1208 (7%)
Frame = -3
Query: 3417 TKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNKKCTAGSLLEKKDNVEVV 3238
T E+QE + + +T ++ + VN + TA S + KKD+ +V
Sbjct: 9128 TAPESQETLNVEIAVTETTVQKITNPSDESAKKDVN-------EDTAVSSIVKKDDKDVN 9180
Query: 3237 IPSVK----VRKKRDPASCSKTISSCKPRKA--SINKTNENLNMPSTQINKQELAGVIVL 3076
S+ KK K I K KA SI++T+E L TQ + E
Sbjct: 9181 KKSLPESGLTTKKEIQGKPEKKIMKKKTEKADSSISETSETLTKDLTQTKQSEPEP---- 9236
Query: 3075 SDNSDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSFANDAALNAKLQGSD- 2899
+ + + +V ++ T K ++++ G S S +DA+ ++Q S+
Sbjct: 9237 AKRTTETSVQDEVKRKTETTSKSKQTTEEHP--QPGGKSDSSISSTSDASEVKQVQQSES 9294
Query: 2898 KMKNTDVATENCVLKDKEKVSHTSNISQEESSGANDVAVNEKLKASDIEKGVDTTVKDAN 2719
+ + E L+ K K+ T + ++E N V+EK K ++K + + +
Sbjct: 9295 EAQKVTEKPETAKLESKSKM--TEDTTKESD---NKETVDEKPKKKVLKKKTEKSDSTIS 9349
Query: 2718 HTKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATAINAATHLEKKNIGNTLQA 2539
T + + GP + + + +K K K I E+K+
Sbjct: 9350 ETSETSAVESAGPSESETQNVAAVDKEKKQKETDEKQKLEAEIAGKKSTEQKS------K 9403
Query: 2538 LDVENKNVEVTIEGKIQGKAKRSE--SKTCSSEKKNIGNTLQA-----LDEENKNVEVTI 2380
L+ E K E + + +++E SK ++EK + Q D K E+
Sbjct: 9404 LEAEAKLKRAAEEDAAKKQKEKTEAASKKAAAEKLELEKQAQINKAAEADAVKKQNELDE 9463
Query: 2379 DRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDVLKDAKVFEKDVAT 2200
K++ K + K + + S K Q+A+E D AK EK
Sbjct: 9464 QNKLEATKKLAAEKLK---------LEEQSAAKSKQAAEE-QAKLDAQTKAKAAEKQTGL 9513
Query: 2199 HQLEKG---SGSNDVVIDKNINA--KVAVEKVDTEINVAVFTEK-------GSISNTLHI 2056
+ EK SGSN+ V +K K EK D+ I+ T K S S T +
Sbjct: 9514 EKDEKSNKDSGSNETVEEKPKKKVLKKKTEKSDSSISQKSDTSKTVAESAGSSESETQKV 9573
Query: 2055 LEDINKKKEATNEEKLPEKGELSAELKPDSDSRSEFVATCVNEVSGQVNNLSIEEFTMSR 1876
+ +K+KE ++KL + E++A+ D S+ E + + +E +
Sbjct: 9574 ADATSKQKETDKKQKL--EAEITAKKSADEKSKLETESKLIKAAEDAAKKQKEKEDKLKL 9631
Query: 1875 DRPEDAEIFKETVGTHQLE-------EKVGSTYAVPSG-EKRDVNLILKEVVT--AANDS 1726
+ A++ + +LE +K AV E + + E T AA +
Sbjct: 9632 E----ADVASKKAAAEKLELEKQAQIKKAAEADAVKKQKELAEKQKLESEAATKKAAAEK 9687
Query: 1725 NLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAGTKSDTVGGRVDEMSGQG 1546
EE+ N A AD V+K+ E+ + +++ S +EK +++E S
Sbjct: 9688 LKLEEQAQINKAAEADAVKKQKELDEKNKLEANKKSAAEKL----------KLEEESAAK 9737
Query: 1545 SQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDT-NEAAVDDKINPEDMMKKV---D 1378
S+ + ++ A D K EK + + D+ ++ VD+K + + KK D
Sbjct: 9738 SKQTVEEQA-KLDAQTKEKTAEKQTGLEKDDKSTKDSESKETVDEKPKKKVLKKKTEKSD 9796
Query: 1377 TAINDAIFTEKKII-------SNIIQISDDENKS----------TGITAEENMLEKGKLN 1249
++I+ T K ++ S +++D K ITA+++ EK KL
Sbjct: 9797 SSISQKSVTSKTVVESGGPSESETQKVADAARKQKETDEKQKLEAEITAKKSADEKSKLE 9856
Query: 1248 SEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVK----DPNNFEKCSVSH--RRQ 1087
+E K + +E+ A + +E+D+ + TE + K +K + + +++
Sbjct: 9857 AESKLKKAAEVEAAKKQKEKDEQLKLDTEAASKKAAAEKLELEKQAQIKKAAEADAVKKE 9916
Query: 1086 EQIGHK---NDNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCTTEVRI 916
+++ K A + A + + KD E + E K + +
Sbjct: 9917 KELAEKQKLESEAATKKAAAEKLKLEEQKKKDAETASIEKQKEQEKLAQEQSKLEVDAKK 9976
Query: 915 AGELHEKRDLKSEFKANTTLETVGGCVNEK-SRHVSQLSTEVLAMS-SEMAEDAKVVG-- 748
+ EK+ L+SE K+ T E V+EK + V + TE S S+ ++ AK V
Sbjct: 9977 SA---EKQKLESETKSKKTEEAPKESVDEKPKKKVLKKKTEKSDSSISQKSDTAKTVAES 10033
Query: 747 ---TDVVTYQLQEPSGDTNQVVVDEAVN-KDEAAAKDCPPTGDEKVGNIAYSLYEENIVK 580
+D T ++ E Q DE + E AAK E+ + + +++
Sbjct: 10034 AGQSDSETQKVSEADKAHKQKESDEKQKLESEIAAK----KSAEQKSKLETEAKTKKVIE 10089
Query: 579 KETAIDEKMQEKWQLKADAASEIVARFVNE--ESGYARQLPTEKLAMSTDTVGDYKISEK 406
E+A +K QE + D+A + + + ES + PT + T + SE
Sbjct: 10090 DESAKKQKEQEDKKKGDDSAKKQKDQKEKQKLESEATSKKPTSEKQKDEKTPQEKAKSEN 10149
Query: 405 DIVSHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVESTS 226
+ V +Q+ K E + T+TV K+ ++T+ + K KE K + +
Sbjct: 10150 ETVMTTEPQQLEVKSE--PKKSDKTETVEKEVASSTEKSDDSKTKEPKEKKKIIKKKKDT 10207
Query: 225 AIAAGYARQLSTEELAMSTDIEEDYKIS-----EKDIVSHL----LQEQVHDK--DEVVG 79
+++LS++E + D+E D +S E D +S LQ++ + D +G
Sbjct: 10208 TKPQEASKELSSDESRI--DLESDISLSLDTVTESDDLSTASTIKLQKESDESGIDSRMG 10265
Query: 78 ETIHATDT 55
+T A D+
Sbjct: 10266 QTSEAEDS 10273
Score = 109 bits (272), Expect = 1e-20
Identities = 251/1195 (21%), Positives = 461/1195 (38%), Gaps = 124/1195 (10%)
Frame = -3
Query: 3237 IPSVKVRKKRDPASCSK--TISSCKPRKASINKTNENLNMPSTQINKQELAGVIVLSDNS 3064
+P K +K+D + K T + + +K ++++ + PS + NK E+ GV +
Sbjct: 12793 LPPAKKSEKKDEVTAEKQSTEALIESKKKEVDESKISEQQPSDK-NKSEVVGVPEKAAGP 12851
Query: 3063 DDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSFANDAALNAKLQGSDKMKNT 2884
+ +K V E V K T KK + S SQ+ N K DK K+
Sbjct: 12852 E----TKKDVSEIEEVPKKKTIKKKTE-KSDSSISQKSNVL--------KPADDDKSKSD 12898
Query: 2883 DVATENC-VLKDKEKVSHTSNISQEESSGAN---DVAVNEKLKASDIEKGVDTTVKDANH 2716
DV ++ +D+ KV+ S + + + + V++K K ++K T D+
Sbjct: 12899 DVTDKSKKTTEDQTKVATDSKLEKAADTTKQIETETVVDDKSKKKVLKK--KTEKSDSFI 12956
Query: 2715 TKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATAINAATHLEKKNIGNTLQAL 2536
++K +V P K ++ A+ I+ K K + V N + + K I + +
Sbjct: 12957 SQKSETPPVVEPTKPAESEAQKIAEVNKAKKQKEVDDN---LKREAEVAAKKIADEKLKI 13013
Query: 2535 DVENKNVEVTIEGKIQGKAKRSE----------SKTCSSEKKNIGNTLQALDEENKNVEV 2386
+ E N++ T E + K K + SK ++EK + Q + V
Sbjct: 13014 EAE-ANIKKTAEVEAAKKQKEKDEQLKLETEVVSKKSAAEKLELEKQAQIKKAAEADA-V 13071
Query: 2385 TIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDVLKDAKVFEKDV 2206
+++ K K +K + + + A +K ++ + +F K K EK V
Sbjct: 13072 KKQKELNEKNKLEAAKKSAADKLKLEEESAAKSKKVSEESVKFGEE----KKTKAGEKTV 13127
Query: 2205 ATHQLEKGSGSNDVVIDKNINA-------------KVAVEKVDTEINVAVFTE------- 2086
Q+E S + K++ A K EK D+ I+ T+
Sbjct: 13128 ---QVESEPTSKKTIDTKDVGATEPADETPKKKIIKKKTEKSDSSISQKSATDSEKVSKQ 13184
Query: 2085 -------KGSISNTLHILEDINKKKEATNEEKLPEKGELSAELKPDSDSRSEFVAT-CVN 1930
K ++S T + E KK+ +EKL E++A+ K ++D +S+ A +
Sbjct: 13185 KEQDEPTKPAVSETQMVTEADKSKKQKETDEKLKLDAEIAAKTKQEADEKSKLDAQEKIK 13244
Query: 1929 EVSGQVNNLSIEEFTMSRDRPEDAEIFKETVGTHQLEE-----KVGSTYAVPSGEKRDVN 1765
+VS +E + K + +LEE K A +++D
Sbjct: 13245 KVSEDDAARKEKELNDKLKLESEIATKKASADKLKLEEQAQAKKAAEVEAAKKQKEKDEQ 13304
Query: 1764 LILKEVVT----AANDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAG 1597
L L AA L ++ I A AD V+K+ E+ + +++ A
Sbjct: 13305 LKLDTEAASKKAAAEKLELEKQAQIKKAAG-ADAVKKQKELDEKNKLE----------AN 13353
Query: 1596 TKSDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDT-NEAAV 1420
KS +++E S S+ + ++ A D K EK + ++ ++ ++ V
Sbjct: 13354 KKSAAGKLKIEEESAAKSKQTVEEQA-KLDAQTKAKTAEKQTKLEKDEKSTKESESKETV 13412
Query: 1419 DDKINPEDMMKKV---DTAINDAIFTEKKII-------SNIIQISDDENKS--------- 1297
D+K + + KK D++I+ T K ++ S +++D K
Sbjct: 13413 DEKPKKKVLKKKTEKSDSSISQKSETSKTVVESAGPSESETQKVADAARKQKETDEKQKL 13472
Query: 1296 -TGITAEENMLEKGKLNSEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNN 1120
ITA+++ EK KL +E K + +E+ A + +E+D+ + TE + K
Sbjct: 13473 EAEITAKKSADEKSKLEAESKLKKAAEVEAAKKQKEKDEQLKLDTEAASKKAAAEK--LE 13530
Query: 1119 FEKCSVSHRRQEQIGHKNDNAVIE--NLQAYAVNNCDTGAKDGNFTEKENASKI--VSSL 952
EK S + E K + E L++ A K +K+ A++I +
Sbjct: 13531 LEKQSHIKKAAEVDAVKKQKELEEKQRLESEAATKKADAEKLKLEEQKKKAAEIALIEIQ 13590
Query: 951 HEDIKCTTE-VRIAGELH---EKRDLKSEFKANTTLETVGGCVNEKSR------------ 820
E K E R+ E EK+ L+SE K+ T E V+EK +
Sbjct: 13591 KEQEKLAQEQSRLEDEAKKSAEKQKLESETKSKQTEEAPKESVDEKPKKKVLKKKTEKSD 13650
Query: 819 ----HVSQLSTEVLAMSSEMAEDAKVVGTDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAK 652
S+ + + + + D +V V Q P T+ + + K E +K
Sbjct: 13651 SSISQKSKSAKSTVDAAETLESDFNLVEKKTVQKVEQSPDESTSATIKRDPAQKTEEISK 13710
Query: 651 DCPPTGDEK---VGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVARFVNEESG 481
GDEK + K+ + +K Q+ + +DA+ V++ ++
Sbjct: 13711 Q--DDGDEKKTTTDGKPPKPEDSEATPKKRVVKKKTQKSDSVASDASLADVSKLSDD--- 13765
Query: 480 YARQLPTEKLAMSTDTVGDYKISEKDIVSHLSQEQIHDKDEVVDETI----HATDT---- 325
+ P +K+ D ISE V + E + E ++ I +TD+
Sbjct: 13766 -VEEKPKKKVLKKKTEKSDSVISETSSVDTIKPESVEIPTEKAEQMILHNRFSTDSAVES 13824
Query: 324 ----VNKDETAATDDTLSEKEKENGNLK-TECSVESTSAI-------AAGYARQLSTEEL 181
+KD+T T D + + K + E S+ S ++ G+A + +++ L
Sbjct: 13825 EPKNAHKDDTEKTTDDMMTRRKSSAIFSDDEQSISSKTSSEGRRRRRRTGFASKFASDTL 13884
Query: 180 AMSTD-IE-EDYKISEKDIVSHLLQEQVHDKDEVVGETIHA-TDTVNKDETAATD 25
A+ D +E E ++E D V+ + + D + E H T+ DE TD
Sbjct: 13885 ALRGDNVEIEAELLAEDDTVTWKVNGKDADLNSRCHEMSHTFFRTLIIDEVEPTD 13939
>gb|ETW48434.1| hypothetical protein PFMALIP_03519 [Plasmodium falciparum
MaliPS096_E11]
Length = 3777
Score = 124 bits (310), Expect = 4e-25
Identities = 236/1145 (20%), Positives = 470/1145 (41%), Gaps = 101/1145 (8%)
Frame = -3
Query: 3138 ENLNMPSTQINKQELAGVIVLSDNSDDAAVSKGKVKE--ANTVIKGATSSKKVKISSTGE 2965
E N+ + ++E ++ +N + +G +E + T ++ + E
Sbjct: 598 EKYNIEDMEETEKENEIEKIMDENKETEQTEEGNTEEFVQEKELNQETLENEIIVDHIKE 657
Query: 2964 NSQERNSFANDAALNAKLQGSDKMKNTDVATENCVLKDKEKVSH--------TSNISQEE 2809
RN ++ L ++ ++ EN + K E+V + +E
Sbjct: 658 EEDTRNVKEQESVL-------EESPIEELPVENNIGKINEEVEEFILNEIPLEEQVPKEL 710
Query: 2808 SSGANDVAVNEKLKASDIEKGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEKM 2629
+ V E+L + +TTV + + T KG + P+ ++K+V++ I + EK
Sbjct: 711 PQEEIEEIVVEELPIDEHLSSEETTVTEED-TFKGQLINEEKPV-EEKSVSEEIPVEEKS 768
Query: 2628 KGKGSVAKNATAINAATHLEKKNIGNTLQALDVENKNV--EVTIEGKIQGKAKRSESKTC 2455
+ + +++ +E+KN+ + + VE KNV E+ +E K + E +
Sbjct: 769 VSE-EIPVEEKSVSEEIPVEEKNVS---EEIPVEEKNVSEEIPVEEKNVSEEIPVEEENV 824
Query: 2454 SSEKKNIGNTLQ--ALDEENKNVEVTIDRKIQGK-GKRSESKTGSIPVMVAGCVNKASCE 2284
S E G ++ +DEE E+T+D KI K E+ +PV
Sbjct: 825 SEEIPEGGIAIEDVPVDEETVTEEITVDEKIYDKLPNEIETVNEEMPVEDETLT------ 878
Query: 2283 KFNQSAKEFTMSTDVLKDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTE-- 2110
Q + E + + + K F + T L VV D ++ EKV E
Sbjct: 879 --EQISSEHERVPEEIIEEKPFTEGEETESLTDEIVEEGVVTDDIPEEQIITEKVQEEEE 936
Query: 2109 -----------INVAVFTEKGSISNTLHILEDINKKKEATNE---EKLPEKGELSAELK- 1975
IN V E S++ L + IN+K + E +++ + G ++ +++
Sbjct: 937 FVTGELSEEDIINEKVQEEDESVTEELPEEDIINEKVQEEEESAYQEIVQDGSVTKDVEY 996
Query: 1974 -----PDSDSRSEFVATCVNEVSGQVNN--LSIEEFTMSRDRPEDAEIFKETVGTHQLEE 1816
D + FV + GQ+ N L +EE ++++ P + +E+V EE
Sbjct: 997 KELVNDDVRDKENFVIE-EDPFKGQLINEGLPVEEEFVTKELP----VKEESVFEELTEE 1051
Query: 1815 KVGSTYAVPSGEKRDVNLILKEV--VTAANDSNLTEEKTISNTAHTADDVRKEMEVAIEE 1642
T +P E + + KEV + + D + EEK+I+N + R +E +E+
Sbjct: 1052 DQSVTKEIPVEE----HSVFKEVDEIESVTDEIVEEEKSITN--ELVKEERTALEEIVEQ 1105
Query: 1641 RMQEKGVSYSE-------KKAGTKSDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMF 1483
R + V +E K+ G+ S+ V V E ++ ++ +++ + A + +
Sbjct: 1106 RPDTEEVEETELVNEEVLKEEGSASEKV---VKEEGSASEKIVEEEGSVTEETASEEIVE 1162
Query: 1482 EKHASTDHLQEQISDTNEAAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDEN 1303
E+ + T+ + +E +V ++ + E+++++ + I ++ + I+ + + S +
Sbjct: 1163 EEGSVTEESSSEEIVEDEGSVTEESSSEEIVEEEGSVIEES--ASEVIVEDEVSASKEIV 1220
Query: 1302 KSTGITAEENMLEKGKLNSEIKTDRTSE---ILAGRSDEERDQVSQFSTEELLMCSGTVK 1132
+ EE + E+G ++ E++ + E I G DE + T+E++ +
Sbjct: 1221 EDEASVTEEVVEEEGAVSDEVQVTESVEDEIINQGIVDEVIVEQEASVTDEIVK-----E 1275
Query: 1131 DPNNFEKCSVSHRRQEQIGHK--------NDNAVIENLQAYAVNNCDTG----AKDGNFT 988
D + E+ +V E + + +V+EN++ N K+ + T
Sbjct: 1276 DESVIEEIAVEETVTEVVEETKPMDEEIVDQGSVVENVEEKKNNGRRNRRSRIIKEASIT 1335
Query: 987 EKENASKIVSSLHEDIKCTTEVRIAGELHEK---RDLKSEFKANTTLETVGGCVNEKSRH 817
E+ + V+ E I+ T+ E+ E+ D+K E + VN++
Sbjct: 1336 EEVEQIEPVTGKVEKIESITD-----EIKEQLVPEDIKEEQLDFEEIVAQRASVNDEKVE 1390
Query: 816 VSQLSTEVLAMSSEMAEDAKVVGTDV-----VTYQLQEPSGDTNQVVVDEAVNKDEAAAK 652
V+ ++ EV + E+ V VT L E + +V E +E + K
Sbjct: 1391 VASITEEVEEEEKSVKEEGSTTEEVVEEQGSVTENLLEEESASQGIVEKEEFVDEEDSVK 1450
Query: 651 DCPPTGDEKVGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVARFVNEESGYAR 472
D EK G++ E +V++E + + EK +L + + EI + VNEE
Sbjct: 1451 D--QNVFEKEGSVT-----EQLVEEEKGLINEDNEKEELITEMSEEI--KSVNEEIEETD 1501
Query: 471 QLPTEKLAMSTDTVGDYKISEKDIVSHLSQEQIHDKD---------EVVDETIHATDTVN 319
E + ++ EK + L +E+ K+ EVVDE + T+ V
Sbjct: 1502 LSTEEIIKQQGLATYEFVEEEKSLTDKLLEEESVTKEVGETELSTQEVVDEKVSVTEEVI 1561
Query: 318 KDETAATDDTL-----SEKEKENGNLKTECSVESTS----AIAAGYARQLSTEELAMSTD 166
++E + +++ L +E+ E G+ TE VE S + G A ++ EE + +
Sbjct: 1562 EEEKSVSEEVLEEGSATEEVVEEGSC-TEIVVEKGSDTEIVVEEGSATEIVVEEGSATEV 1620
Query: 165 IEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDTVNKDE------------TAATDD 22
+ E+ +SE+ +L+E+ +EVV E + ++D V K + A D+
Sbjct: 1621 VVEEGSVSEE-----MLEEEGSATEEVVEEGL-SSDNVQKSKGVIENVGEIYSVKTAKDE 1674
Query: 21 TLSEK 7
+++EK
Sbjct: 1675 SMNEK 1679
Score = 116 bits (290), Expect = 8e-23
Identities = 234/1242 (18%), Positives = 504/1242 (40%), Gaps = 105/1242 (8%)
Frame = -3
Query: 3417 TKIENQE---NAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNKKCTAGSLLEKKDNV 3247
TK+ N++ T V E + LE++ ++ +V + C E+ +
Sbjct: 1806 TKLANEKIIPEVSVTENVVEKEGLDTEEVLEEDESITEEIVEEEVSACEEIVEEEESSSE 1865
Query: 3246 EVVIPSVKVRKKRDPASCSKTISSCKPRKASINKTNENLNMPSTQINKQELAGVIVLSDN 3067
E+V + + +S + + + I + E+ + + + +I +
Sbjct: 1866 EIV--------EEEESSSEEIVEEEESSSEEIVEEEESSSEEIVEEEESSSEEIIEEVSS 1917
Query: 3066 SDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSFANDAALNAKLQGSDKMKN 2887
+++ +G V E + +T+ + I S E E F + + + +++
Sbjct: 1918 TEEVLEEEGSVTEEIVEEEVSTTEEVKDIGSVSEEVLEEEGFGTEEFVGQQGSVIEEIVE 1977
Query: 2886 TDVATENCVLKDKEKVSHTSNISQEESSGANDVAVNEKLKASDIEKGVDTTVKDANHTKK 2707
T+ +TE VL+D S+ I QEE A ++ V+E++ ++ VD + + K
Sbjct: 1978 TESSTEK-VLEDVG--SNVEEIVQEEGPVAQEI-VHEEVSTTEKHDEVDRSTTEEIVEKV 2033
Query: 2706 GNVS--IMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATAINAATH-LEKKNIGNTLQAL 2536
G+VS I+V + + + + S+ E++ + + + T + +K + + + L
Sbjct: 2034 GSVSEEIIVEEVSASEEIVEEGSVTEEVVEEEKLINEVGETESVTEEIVQKEVSDAEEVL 2093
Query: 2535 DVENKNVEVTIE----------------------GKIQGKAKRSESKTCSSEKKNIGNTL 2422
E E +E G + K E T + + T
Sbjct: 2094 GQEGSMNEEILEKESIVEEIVGPEGSVTEEIVDHGSFAEEVKEEELVTEEAVQYEGSVTE 2153
Query: 2421 QALDEENKNVEVTIDRK-----IQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEF 2257
+ +EE+ I+ I+ KG ++ + VN+ S ++
Sbjct: 2154 EIKEEESITENEAIEESAFAEIIEEKGPNNDEIVKEEGLDTEEIVNEVSVTDEVIEEEKL 2213
Query: 2256 TMSTDVLKDAKVFEKDV-----ATHQL--------EKGSGSNDVVIDKNINAKVAVEKVD 2116
V ++ V EK V AT L EK S ++ ++ VA E V+
Sbjct: 2214 VNEQIVGEERSVTEKPVEVERSATEDLVEEEASVTEKVSVHEGSTTEQILDESVAEEIVE 2273
Query: 2115 TEINV--AVFTEKGSISNTLH----ILEDINKKKEATNEEKLPEKGELSAELKPDSDSRS 1954
E++V + E+ S+ + ++E+I +++E+ EE L E+ S E+ D
Sbjct: 2274 EEVSVDDKIIEEEVSVDEVVEEEGSVIEEIVEEEESVPEEILEEELSGSEEVLEDEWVTD 2333
Query: 1953 EFVATCVNEVSGQVNNLSIEEFTMSRDRPEDAEIFKETVGTH--QLEEKVGSTYAVPSGE 1780
F+ V ++ + E +++ + ED ++ V ++EE +G
Sbjct: 2334 AFMGQ-EGSVIEEIEEIVDGEGSITEEIVEDGSANEKIVEEEPSRVEEVLGKE------- 2385
Query: 1779 KRDVNLILKEVVTAANDSNLTEE-KTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKK 1603
+++E++ + E+ KT+S + + + + EV EE + EK V E
Sbjct: 2386 ----GFVIEEIIEEGSVIEQVEDTKTVSEKSEESSAIEEVKEVKEEESISEKIVEKEES- 2440
Query: 1602 AGTKSDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHAS-TDHLQEQISDTNEA 1426
V E + + +T+K+ DV+ E+ S T+ + EQ E
Sbjct: 2441 -----------VTEEIVRQEESTTEKIV--KDVSPTEDFVEQTDSVTEKVIEQEGSNTEV 2487
Query: 1425 A--VDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGITAE--------- 1279
A V++K + D ++ D ++N + EKK ++ +I D+ +++ I E
Sbjct: 2488 AEDVEEKESASDEHEQEDVSVNAQVTYEKKSVTK--EIVDEVSRTEEIVEENGSVTEGVD 2545
Query: 1278 ------ENMLEKGKLNSEIKTDR--TSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPN 1123
E ++E+ + E+ D T E++ S + TEE++ +G+V +
Sbjct: 2546 ETGSVTEEIIEEATVTEEVVEDGSVTEEVVEDGSVIQEVVEDGSVTEEIVQENGSVTEEI 2605
Query: 1122 NFEKCSVSHRRQEQIGHKNDNAVIENLQAYAVNNCDTGAKDGNFTEK-ENASKIVSSLHE 946
E+ SV+ +E++ + E VN D + FTE+ E + + E
Sbjct: 2606 VEEEGSVNEEVEEEVSVSGERRKDET---ELVN--DEIVEQAPFTEEVEEQVSVNDEIIE 2660
Query: 945 DIKCTTEVRIAGELHEKRDLKSEFKANTTLETVG--GCVNEKSRHVSQLSTEVLAMSSEM 772
D V + + E + E + +E V G V E+ ++ E+L S +
Sbjct: 2661 DASVAEAVEESESITESVSQEEETEKGFVIEKVEETGAVTEEIVQDGLITEEILEESESV 2720
Query: 771 --------AEDAKVVGTDVVTYQLQEPSGDTNQVVVDEA------VNKDEAAAKDCPPTG 634
++ +++ T+ +T ++ +G T++ +V+E V + E+ ++ G
Sbjct: 2721 NGEIINKESDAEEILETEFLTEEVVGQAGSTSEEIVEEEGSVTKEVEEKESVTEELVDEG 2780
Query: 633 D------EKVGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVAR-------FVN 493
E+ G+IA + EE +E DE E+ K +A+E + + FV
Sbjct: 2781 SVTEEVVEQGGSIAQEIVEEESATEEIIRDETNVEEVLEKEGSATEEIVQDGSGTNDFVG 2840
Query: 492 EESGYARQLPTEKLAMSTDTVGDYKISEKDIVSHLSQEQIHDKDEVVDETIHATDTVNKD 313
++ ++ E+++ + + + K I + +E I +++V++E++ + V +
Sbjct: 2841 KQGSVIEEVVEEEISTTEEKL---KEEASAIEEFVEEESI--REDVLEESLVTENVVGQQ 2895
Query: 312 ETAATDDTLSEKEKENGNLKTECSVESTSAIAAGYARQLSTEELAMSTDIEEDYKISEKD 133
E+ ++E+ + TE VE ++ ++ +E +++ +I ED ++ ++
Sbjct: 2896 ES------VTEEIVDGEGSFTEDIVEEEESVT----EEIVVDEESVTKEIVEDEELVTEE 2945
Query: 132 IVSHLLQEQVHDKDEVVGETIHATDTVNKDETAATDDTLSEK 7
IV +++ +E+V + T+ + +DE + T++ + E+
Sbjct: 2946 IV----EDEGSFTEEIVEDEGSFTEEIVEDEGSFTEEVIEER 2983
Score = 111 bits (278), Expect = 2e-21
Identities = 230/1232 (18%), Positives = 494/1232 (40%), Gaps = 113/1232 (9%)
Frame = -3
Query: 3363 ENSMVTQGLEKESNVIVNVVIGDNKKCTAGSLLEKKDNVEVVIPSVKVRKK--RDPASCS 3190
E VT + +E I N ++ + + ++E++ + E V + V ++ ++ S S
Sbjct: 1072 EIESVTDEIVEEEKSITNELVKEERTALE-EIVEQRPDTEEVEETELVNEEVLKEEGSAS 1130
Query: 3189 KTISSCKPRKASINKTNENLNMPSTQINKQELA---GVIVLSDNSDDAAVSKGKVKEANT 3019
+ + K ++ K E + + +E+ G + +S++ +G V E
Sbjct: 1131 EKV--VKEEGSASEKIVEEEGSVTEETASEEIVEEEGSVTEESSSEEIVEDEGSVTEE-- 1186
Query: 3018 VIKGATSSKKVKISSTGENSQERNSFANDAALNAKLQGSDKMKNTDVATENCVLKDKEKV 2839
SS+ E +E S ++A S+ + +V+ +++D+ V
Sbjct: 1187 -------------SSSEEIVEEEGSVIEESA-------SEVIVEDEVSASKEIVEDEASV 1226
Query: 2838 SHTSNISQEESSGANDVAVNEKLKASDIEKG-VDTTVKDANHTKKGNV----SIMVGPIK 2674
T + +EE + +++V V E ++ I +G VD + + + + ++ I
Sbjct: 1227 --TEEVVEEEGAVSDEVQVTESVEDEIINQGIVDEVIVEQEASVTDEIVKEDESVIEEIA 1284
Query: 2673 QQKNVAKGIS----MNEKMKGKGSVAKNATAINAATHLEKKNIGNTLQALDVENKNVEVT 2506
++ V + + M+E++ +GSV +N EKKN G + + K +T
Sbjct: 1285 VEETVTEVVEETKPMDEEIVDQGSVVENVE--------EKKNNGRRNRRSRII-KEASIT 1335
Query: 2505 IEGK----IQGKAKRSESKTCSSEKKNIGNTLQ---------------ALDEENKNVEVT 2383
E + + GK ++ ES T +++ + ++ DE+ + +T
Sbjct: 1336 EEVEQIEPVTGKVEKIESITDEIKEQLVPEDIKEEQLDFEEIVAQRASVNDEKVEVASIT 1395
Query: 2382 IDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSA-----KEFTMSTDVLKDAKVF 2218
+ + + K + E T V G V + E+ + S +EF D +KD VF
Sbjct: 1396 EEVEEEEKSVKEEGSTTEEVVEEQGSVTENLLEEESASQGIVEKEEFVDEEDSVKDQNVF 1455
Query: 2217 EKDVATHQLEKGSGSNDVVIDKN--INAKVAVEKVDTEINVAVFTEKGSISNTLHILEDI 2044
EK+ GS + +V ++ IN E++ TE++ + + I T E+I
Sbjct: 1456 EKE--------GSVTEQLVEEEKGLINEDNEKEELITEMSEEIKSVNEEIEETDLSTEEI 1507
Query: 2043 NKKKEATNEEKLPEKGELSAELKPDSDSRSEFVATCVNEVSGQVNNLSIEEFTMSRDRPE 1864
K++ E + E+ L+ +L + E T ++ +S+ E + ++
Sbjct: 1508 IKQQGLATYEFVEEEKSLTDKLLEEESVTKEVGETELSTQEVVDEKVSVTEEVIEEEKSV 1567
Query: 1863 DAEIFKETVGTHQLEEKVGSTYAVPSGEKRDVNLILKEVVTAANDSNLTEEKTISNTAHT 1684
E+ +E T ++ E+ GS + + D ++++E + + EE + +
Sbjct: 1568 SEEVLEEGSATEEVVEE-GSCTEIVVEKGSDTEIVVEE---GSATEIVVEEGSATEVVVE 1623
Query: 1683 ADDVRKEM---EVAIEERMQEKGVSYS--EKKAGTKSDTVGGRVDEMSGQGSQLSTKKLA 1519
V +EM E + E + E+G+S +K G + G + + + +K+
Sbjct: 1624 EGSVSEEMLEEEGSATEEVVEEGLSSDNVQKSKGVIENV--GEIYSVKTAKDESMNEKIP 1681
Query: 1518 ISSDVAVDPKMFEKHASTDHLQEQISDTNEAAVDDKINPEDMMK---------------- 1387
+ VD + F+ TD++ + D N + ++ P + K
Sbjct: 1682 LEKSSFVDDESFKGQGPTDNVS--VEDVNSEDIINEHTPLEETKIEELPTEYITTADIHT 1739
Query: 1386 -------------KVDTAINDAIFTEKKIISNII----QISDD------------ENKST 1294
K++ + A F E+KI NI +++D + +S
Sbjct: 1740 KGETETKYNLIYEKINEEVEKAKFQEEKITENIPVERESVTEDIVQEPSLAQEVEQKESD 1799
Query: 1293 GITAEENMLEKGKLNSEIKTDRTSEILAGRSDEERDQVSQFSTEELL-----MCSGTVKD 1129
EE L K+ E+ G EE + + TEE++ C V++
Sbjct: 1800 TNEIEETKLANEKIIPEVSVTENVVEKEGLDTEEVLEEDESITEEIVEEEVSACEEIVEE 1859
Query: 1128 PNNFEKCSVSHRRQ--EQIGHKNDNAVIENLQAYAVNNCDTGAKDGNFTEK--ENASKIV 961
+ + V E+I + +++ E ++ ++ + ++ + +E+ E S
Sbjct: 1860 EESSSEEIVEEEESSSEEIVEEEESSSEEIVEEEESSSEEIVEEEESSSEEIIEEVSSTE 1919
Query: 960 SSLHEDIKCTTEV--RIAGELHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLA 787
L E+ T E+ E +D+ S + LE G E + E++
Sbjct: 1920 EVLEEEGSVTEEIVEEEVSTTEEVKDIGSV--SEEVLEEEGFGTEEFVGQQGSVIEEIVE 1977
Query: 786 MSSEMAEDAKVVGTDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAY 607
S + + VG++V ++ + G Q +V E V+ E + T +E V +
Sbjct: 1978 TESSTEKVLEDVGSNVE--EIVQEEGPVAQEIVHEEVSTTEKHDEVDRSTTEEIVEKVG- 2034
Query: 606 SLYEENIVKKETAIDEKMQEKWQLKADAASEIVARFVNEESGYARQLPTEKLAMSTDTVG 427
S+ EE IV++ +A +E ++E + E + V E ++ ++++ + + +G
Sbjct: 2035 SVSEEIIVEEVSASEEIVEEGSVTEEVVEEEKLINEVGETESVTEEIVQKEVSDAEEVLG 2094
Query: 426 -----DYKISEKD-IVSHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKEN 265
+ +I EK+ IV + + +E+VD A + K+E T++ + +
Sbjct: 2095 QEGSMNEEILEKESIVEEIVGPEGSVTEEIVDHGSFAEEV--KEEELVTEEAVQYEGSVT 2152
Query: 264 GNLKTECSVESTSAIAAGYARQL------STEELAMSTDIEEDYKISEKDIVSHLLQEQV 103
+K E S+ AI ++ + +E+ ++ + ++E + +++E+
Sbjct: 2153 EEIKEEESITENEAIEESAFAEIIEEKGPNNDEIVKEEGLDTEEIVNEVSVTDEVIEEEK 2212
Query: 102 HDKDEVVGETIHATDTVNKDETAATDDTLSEK 7
+++VGE T+ + E +AT+D + E+
Sbjct: 2213 LVNEQIVGEERSVTEKPVEVERSATEDLVEEE 2244
Score = 109 bits (273), Expect = 7e-21
Identities = 254/1293 (19%), Positives = 505/1293 (39%), Gaps = 152/1293 (11%)
Frame = -3
Query: 3459 GSVNQGVCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNKKCT 3280
GSV + V + + S K E + +A V V+ E S+ + +EKE +V +V + T
Sbjct: 2396 GSVIEQVEDTKTVSEKSE-ESSAIEEVKEVKEEESISEKIVEKEESVTEEIV-RQEESTT 2453
Query: 3279 AGSLLEKKDNVEVVIPSVKVRKKRDPASCSKT-ISSCKPRKASINKTNE----NLNMPST 3115
+ + + V + V +K S T ++ K S + +E ++N T
Sbjct: 2454 EKIVKDVSPTEDFVEQTDSVTEKVIEQEGSNTEVAEDVEEKESASDEHEQEDVSVNAQVT 2513
Query: 3114 QINKQELAGVIVLSDNSDDAAVSKGKVKEA--------NTVIKGATSSKKV-KISSTGEN 2962
K ++ +++ G V E +I+ AT +++V + S E
Sbjct: 2514 YEKKSVTKEIVDEVSRTEEIVEENGSVTEGVDETGSVTEEIIEEATVTEEVVEDGSVTEE 2573
Query: 2961 SQERNSFANDAALNAKLQGSDKMKNTDVATENCVLKD-------KEKVSHTSNISQEESS 2803
E S + + + +N V TE V ++ +E+VS + ++E+
Sbjct: 2574 VVEDGSVIQEVVEDGSVTEEIVQENGSV-TEEIVEEEGSVNEEVEEEVSVSGERRKDETE 2632
Query: 2802 GANDVAVNEKLKASDIEKGV---DTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEK 2632
ND V + ++E+ V D ++DA+ + +++ +++ + +S E+
Sbjct: 2633 LVNDEIVEQAPFTEEVEEQVSVNDEIIEDAS---------VAEAVEESESITESVSQEEE 2683
Query: 2631 MKGKGSVAKNATAINAATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCS 2452
+ KG V + A T E G + + E+++V I K + E++ +
Sbjct: 2684 TE-KGFVIEKVEETGAVTE-EIVQDGLITEEILEESESVNGEIINKESDAEEILETEFLT 2741
Query: 2451 SEKKN-IGNTLQALDEENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFN 2275
E G+T + + EE +V ++ K ES T + + G V + E+
Sbjct: 2742 EEVVGQAGSTSEEIVEEEGSVTKEVEEK--------ESVTEEL--VDEGSVTEEVVEQGG 2791
Query: 2274 QSAKEF----TMSTDVLKDA----KVFEKD-VATHQL-EKGSGSNDVVIDKNINAKVAVE 2125
A+E + + ++++D +V EK+ AT ++ + GSG+ND V V E
Sbjct: 2792 SIAQEIVEEESATEEIIRDETNVEEVLEKEGSATEEIVQDGSGTNDFV---GKQGSVIEE 2848
Query: 2124 KVDTEINVAVFTEKGSISNTLHILEDINKKKEATNEEKLPEK--GELSAELKPDSDSRSE 1951
V+ EI+ K S +E+ + +++ E + E G+ + + D
Sbjct: 2849 VVEEEISTTEEKLKEEASAIEEFVEEESIREDVLEESLVTENVVGQQESVTEEIVDGEGS 2908
Query: 1950 FVATCVNEVSGQVNNLSIEEFTMSRDRPEDAEIFKETVG------THQLEEKVGS-TYAV 1792
F V E + ++E +++++ ED E+ E + T ++ E GS T +
Sbjct: 2909 FTEDIVEEEESVTEEIVVDEESVTKEIVEDEELVTEEIVEDEGSFTEEIVEDEGSFTEEI 2968
Query: 1791 PSGEKRDVNLILKE--VVTAANDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVS 1618
E +++E ++ D+ EK + D + E +EE EK V+
Sbjct: 2969 VEDEGSFTEEVIEERSLIEEVEDTETVAEKEEGSVIKEIIDEKSLTEKIVEE---EKSVT 3025
Query: 1617 YS-EKKAGTKSDTVGGR--VDEMSGQGSQLSTKKLA---ISSDVAVDPKMFEKHASTDHL 1456
E+K K + R V+E + +LA I D+ V ++ E +TD
Sbjct: 3026 EEVEEKESVKEEVEEQRLVVEEEGSATEGIVEDRLATEGIVDDILVTEEIVEDGLATDEF 3085
Query: 1455 QEQISDTNEAAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGITAEE 1276
EQ E +DD+ + + + + + + N+ I +I I + + E
Sbjct: 3086 VEQQGSIIEEVLDDEGSVTEEIVEEEGSPNEEIVEGVSVIEEDDNIEPVSEEIVEGSVTE 3145
Query: 1275 NMLEKGKLNSEIKTDR-------------------------TSEILAGRSDEERDQVSQF 1171
M+++G L +E+ D T EI+ D + +
Sbjct: 3146 EMIKEG-LENEVILDEDSITEEALEKEGSVSEEIVEEMGSLTEEIVDEERSTSEDMIEEG 3204
Query: 1170 S-TEELLMCSGTVKDPNNFEKCSVSHR--RQEQIGHKNDNAVIE-NLQAYAVNNCDTGAK 1003
S +EE++ V++ E+ SV ++++ K IE N + + + G+
Sbjct: 3205 SASEEIIQEESQVEEV--VEEVSVIDEIVEEDELDTKEVVEEIEFNTEEVVEHKEEEGSV 3262
Query: 1002 DGNFTEKENASKIVSSLHEDIKCTTEVRIA------GELHEKRDLKSEFKANTTLE---- 853
++E + + E++ TE + E+ E+R + E + N +E
Sbjct: 3263 AEEIVQEEKEGSVNEEIIEEVGSITEEMVEQDVSDNEEIVEERSVIEEAEENVWIEKEVE 3322
Query: 852 ----------TVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVG--------------- 748
V+E++ ++ E+L SS++ ED KV
Sbjct: 3323 EEGLDNEEVIDEEDSVSEQAEEEVYINEEILKESSDV-EDVKVENELMNEEVNEETQSVA 3381
Query: 747 ------TDVVTYQLQEPSGDTNQVVVDEAVNKDEA---------AAKDCPPTGD------ 631
++ Y ++E T +VVVDE N E +D T D
Sbjct: 3382 ENNEEDKELDNYVVEETESVTEEVVVDEVPNSKEVQEIESIIEEIVEDGLTTDDLVGQQG 3441
Query: 630 -------EKVGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVA------RFVNE 490
E+VG+ + + EE + +E E + E ++ +I+ V E
Sbjct: 3442 SVIEEVVEEVGSDSEEIVEEASITEEVEKKESVTEDILVEESVTGDILVEGSVTEEVVGE 3501
Query: 489 ESGYARQLPTEKLAMSTDTVGD--YKISEKDIVSHLSQEQIHDKDEVVDETIHATDTVNK 316
E + ++ TE+ +++ + V + E D + +++E + ++ V +E + +V
Sbjct: 3502 EKLVSEEIVTEEGSVAQEIVEEDAPATEEIDEIESVTEEVVEEEGPVDEEIVQEEGSVT- 3560
Query: 315 DETAATDDTLSEKEKENGNLKTECSVESTSAIAAGYARQLSTEELAMSTDIEEDYKISEK 136
+E + + E +E G+ E VE SA + TEE+ ++ + +
Sbjct: 3561 EEIIQGESKVEEVVEEQGSENEEIFVEEVSASQEIVQNESGTEEILEKVSASQEI-VQDG 3619
Query: 135 DIVSHLLQEQVHDKDEVVGETIHATDTVNKDET 37
+ +++EQ +EVV E T + ++E+
Sbjct: 3620 SVTEQIIEEQKPVTEEVVNEEESITHEIIQEES 3652
Score = 93.6 bits (231), Expect = 6e-16
Identities = 206/971 (21%), Positives = 393/971 (40%), Gaps = 43/971 (4%)
Frame = -3
Query: 2784 VNEKLKASDIEKGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNE------KMKG 2623
+ E K ++IEK +D K+ T++GN V Q+K + + NE K +
Sbjct: 605 MEETEKENEIEKIMDEN-KETEQTEEGNTEEFV----QEKELNQETLENEIIVDHIKEEE 659
Query: 2622 KGSVAKNATAINAATHLEKKNIGNTLQALDVENKNV---EVTIEGKIQGKAKRSESKTCS 2452
K ++ + +E+ + N + ++ E + E+ +E ++ + + E +
Sbjct: 660 DTRNVKEQESVLEESPIEELPVENNIGKINEEVEEFILNEIPLEEQVPKELPQEEIEEIV 719
Query: 2451 SEKKNIGNTLQALDEENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQ 2272
E+ I L + +E E T ++ + K E K+ S + V K+ E+
Sbjct: 720 VEELPIDEHLSS-EETTVTEEDTFKGQLINEEKPVEEKSVSEEIPVE---EKSVSEEI-- 773
Query: 2271 SAKEFTMSTDVLKDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTEINVAVF 2092
+E ++S ++ + K +++ EK V +KN++ ++ VE E NV+
Sbjct: 774 PVEEKSVSEEIPVEEKNVSEEIPVE--EKNVSEEIPVEEKNVSEEIPVE----EENVSEE 827
Query: 2091 TEKGSISNTLHILEDINKKKEATNEE---------KLPEKGELSAELKPDSDSRSEFVAT 1939
+G I+ +ED+ +E EE KLP + E E P D E +
Sbjct: 828 IPEGGIA-----IEDVPVDEETVTEEITVDEKIYDKLPNEIETVNEEMPVED---ETLTE 879
Query: 1938 CVNEVSGQVNNLSIEEFTMSRDRPEDA---EIFKETVGTHQLEE------KVGSTYAVPS 1786
++ +V IEE + ++ EI +E V T + E KV +
Sbjct: 880 QISSEHERVPEEIIEEKPFTEGEETESLTDEIVEEGVVTDDIPEEQIITEKVQEEEEFVT 939
Query: 1785 GEKRDVNLILKEVVTAANDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQE----KGVS 1618
GE + ++I ++V D ++TEE + + + V++E E A +E +Q+ K V
Sbjct: 940 GELSEEDIINEKV--QEEDESVTEELPEEDIIN--EKVQEEEESAYQEIVQDGSVTKDVE 995
Query: 1617 YSEKKAGTKSDTVGGRVDEMSGQGSQLSTKKLAISSD-VAVDPKMFEKHASTDHLQEQIS 1441
Y E D ++E +G QL + L + + V + + E+ + +E S
Sbjct: 996 YKELVNDDVRDKENFVIEEDPFKG-QLINEGLPVEEEFVTKELPVKEESVFEELTEEDQS 1054
Query: 1440 DTNEAAVDDKINPEDMMKKVDT--AINDAIFTEKKIISNIIQISDDENKSTGITAEENML 1267
T E V++ + K+VD ++ D I E+K I+N +
Sbjct: 1055 VTKEIPVEE----HSVFKEVDEIESVTDEIVEEEKSITNEL------------------- 1091
Query: 1266 EKGKLNSEIKTDRTS--EILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKCSVSHR 1093
+K +RT+ EI+ R D E + ++ EE+L G+ + E+ S S +
Sbjct: 1092 --------VKEERTALEEIVEQRPDTEEVEETELVNEEVLKEEGSASEKVVKEEGSASEK 1143
Query: 1092 RQEQIGHKNDNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCTTEVRIA 913
E+ G + E + ++G+ TE+ ++ +IV ED TE +
Sbjct: 1144 IVEEEGSVTEETASEEIVE----------EEGSVTEESSSEEIV----EDEGSVTEESSS 1189
Query: 912 GELHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVGTDVVT 733
E+ E+ E A+ + V ++ ++ + +++ E+ E+ V +V
Sbjct: 1190 EEIVEEEGSVIEESASEVI------VEDEVSASKEIVEDEASVTEEVVEEEGAVSDEV-- 1241
Query: 732 YQLQEPSGDT--NQVVVDEAVNKDEAAAKDCPPTGDEKV-GNIAYSLYEENIVKKETAID 562
Q+ E D NQ +VDE + + EA+ D DE V IA +V++ +D
Sbjct: 1242 -QVTESVEDEIINQGIVDEVIVEQEASVTDEIVKEDESVIEEIAVEETVTEVVEETKPMD 1300
Query: 561 EKMQEKWQLKADAASEIVARFVNEESGYARQLP----TEKLAMSTDTVGDYKISEKDIVS 394
E++ ++ + + + N S ++ E++ T V + +I
Sbjct: 1301 EEIVDQGSVVENVEEKKNNGRRNRRSRIIKEASITEEVEQIEPVTGKVEKIESITDEIKE 1360
Query: 393 HLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVESTSAIAA 214
L E I ++ +E + +VN DE E E+E ++K E S
Sbjct: 1361 QLVPEDIKEEQLDFEEIVAQRASVN-DEKVEVASITEEVEEEEKSVKEEGS--------- 1410
Query: 213 GYARQLSTEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDTVNKDETA 34
+TEE+ +EE ++E + + + +K+E V E D ++
Sbjct: 1411 ------TTEEV-----VEEQGSVTENLLEEESASQGIVEKEEFVDEEDSVKDQNVFEKEG 1459
Query: 33 ATDDTLSEKEK 1
+ + L E+EK
Sbjct: 1460 SVTEQLVEEEK 1470
>ref|WP_010169103.1| hypothetical protein [Epulopiscium sp. 'N.t. morphotype B']
Length = 1888
Score = 120 bits (301), Expect = 4e-24
Identities = 246/1193 (20%), Positives = 445/1193 (37%), Gaps = 68/1193 (5%)
Frame = -3
Query: 3387 STVTAVRSENSMVTQGLEKESNVIVNVVIGDNKKCTAGSLLEKKDNVEVVIPSVKVRKKR 3208
+T+ + E + + + +E V G+ + EK D E V SV+
Sbjct: 387 TTLNIIPVEKAAILNIVPEEKTATSETVSGEKTDASETVSAEKADASETV--SVEKVATS 444
Query: 3207 DPASCSKTISSCKPRKASINKTNENLNMPSTQINKQELAGVIVLSDNSDDAAVSKGKVKE 3028
+ S KT++S S KT+ + + + + + E +D S+ + K E
Sbjct: 445 ETVSAEKTVASATSETVSGEKTDASETVSAGKADASETVSA-EKADASETVSAGKADASE 503
Query: 3027 ANTVIKGATS--------------------------SKKVKISSTGENSQERNSFANDAA 2926
+ K ATS ++K S+T E + A++
Sbjct: 504 TVSAEKAATSETVSAGKADASETVSAEKAVTSETVSAEKTVASATSETTSAEKPDASETV 563
Query: 2925 LNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQEESSGANDV--------AVNEKL 2770
K S+ V +K S T +S E++ + V A +E +
Sbjct: 564 SGEKTDASETTSGEKTDASETVSAEKADASET--VSAEKADASETVSAEKAVASATSETV 621
Query: 2769 KA--SDIEKGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNAT 2596
A +D + V DA+ T + + +K A EK +V+
Sbjct: 622 SAGKADASEIVSAEKTDASETVSAEKADASETVSAEKPDASETEAGEKADASETVSAGKA 681
Query: 2595 AINAATHLEKKNIGNTL---QALDVENKNVEVTIEGKIQGKAKRSESKTCSSEKKNIGNT 2425
A + T K T+ +A E + E + + K + S+T S+EK + T
Sbjct: 682 ATSETTSAGKAATSETVSAGKAATSETVSAEKAVTSETVSVEKAATSETVSAEKADASET 741
Query: 2424 LQALDEENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMST 2245
+ A E + T+ G+++++ ++ A S EK SA T+S
Sbjct: 742 VSA---EKTDASETVS------GEKTDASE-TVSAEKADASETVSAEKTVASATSETVSA 791
Query: 2244 DVLKDAKVFEKDVA----THQLEKGSGSNDVVIDKNINAKVAVEKVDTEINVAVFTEKGS 2077
+ ++ + A T EK S V +K +A V T+ + V EK
Sbjct: 792 EKAVTSETVSAEKAATSETVSAEKTDASETVSAEKT-DASETVSGEKTDASETVSGEKTD 850
Query: 2076 ISNTLHI-----LEDINKKKEATNEEKLPEKGELSAELKPDSDSRSEFVATCVNEVSGQV 1912
S T+ E ++ +K T+E + EK E S + + SE + E +
Sbjct: 851 ASETVSAEKPDASETVSGEKAVTSETESGEKAEASETVSGEKTDASETTSAENGEKAATS 910
Query: 1911 NNLSIEEFTMSRDRPEDAEIFKETVGTHQLEEKVGS-TYAVPSGEKRDVNLILKEVVTAA 1735
+S+E+ S + + ETV E+ V S T S EK D A
Sbjct: 911 ETVSVEKADASETVSAEKAVTSETVSG---EKAVASGTSETVSAEKPD-----------A 956
Query: 1734 NDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAGTKSDTVGGRVDEMS 1555
+++ + E+ +S + T + + + + + S +KA S+TV E +
Sbjct: 957 SETEVGEKTVVSEASETVSGEKTDASETVSAEKADASETVSAEKADA-SETVSA---EKA 1012
Query: 1554 GQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDTNEAAVDDKINPEDMMKKVDT 1375
+S K A S V+ + + A+++ + + +D +E +K + + +
Sbjct: 1013 DASETVSAGKAATSETVSAEKAV--ASATSETVSAEKTDASETVSAEKADASETVSAEKA 1070
Query: 1374 AINDAIFTEKKIISNIIQISDDENKSTGITAEENMLEKGKLNSEIKTDRTSEILAGRSDE 1195
++ + K S + + E T + S KTD + + A ++D
Sbjct: 1071 DASETVSAGKAATSETVSV---EKTDASETVSGEKTATSETVSAGKTDASETVSAEKAD- 1126
Query: 1194 ERDQVSQFSTEELLMCSGTVKDPNNFEKCSVSHRRQEQIGHKNDNAVIENLQAYAVNNCD 1015
S+ + E S TV + K + S ++ +E
Sbjct: 1127 ----ASETVSAEKTDASETV----SAGKAATSETTSAGKAATSETVSVEK---------- 1168
Query: 1014 TGAKDGNFTEKENASKIVSSLHEDIKCTTEVRIAGELHEKRDLKSEFKANTTLETVGGCV 835
A + EK S+ VS+ K T ++GE + + S K T+ ETV
Sbjct: 1169 AAASETVSAEKAVTSETVSA----EKAATSEPVSGEKTDASETVSAEKTATS-ETVSAGK 1223
Query: 834 NEKSRHVSQLSTEVLAMSSEMAEDAKVVGTDVVTYQLQEPSGDTNQVVVD--EAVNKDEA 661
S VS T+ +SE K V ++ V+ + + S + D E V+ ++A
Sbjct: 1224 AATSETVSGEKTD----ASETVSAEKTVASETVSVEKTDASETISAEKADASETVSAEKA 1279
Query: 660 AAKDCPPTGDEKVGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVARFVNEESG 481
A + T EK S E + ++T E + + KADA+ + A E++
Sbjct: 1280 DASE--TTSAEKT---VASATSETVSGEKTDASETVSAE---KADASETVSA----EKTD 1327
Query: 480 YARQLPTEKLAMSTDTVGDYKISEKDIVSHLSQEQIHDKDEVVDETIHATDTVNKDETAA 301
+ + EK+A S +TV K +S E+ + V E A++TV+ E AA
Sbjct: 1328 ASETVSVEKVATS-ETVSAEKTVASAAPETVSAEKTDASETVSGEKTDASETVS-GEKAA 1385
Query: 300 TDDTLSEKEKEN------GNLKTECSVESTSAIAAGYARQLSTEELAMS-------TDIE 160
T +T+S ++ + G +V + +A+ + +S E+ S TD
Sbjct: 1386 TSETVSAEKADTSETVSAGKADASETVSAEKPVASATSETVSAEKADASETVSVEKTDAS 1445
Query: 159 EDYKISEKDIVSHLLQ----EQVHDKDEVVGETIHATDTVNKDETAATDDTLS 13
E +EK + S + E+ + V GE A++TV+ +T T +T+S
Sbjct: 1446 ETVS-AEKTVASATSETVSAEKADASETVSGEKADASETVSAGKT-VTSETVS 1496
Score = 105 bits (261), Expect = 2e-19
Identities = 219/1071 (20%), Positives = 393/1071 (36%), Gaps = 74/1071 (6%)
Frame = -3
Query: 3465 KTGSVNQGVCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNKK 3286
+T S + V + ++S T + +A V+A +++ S + +++ V+ D +
Sbjct: 605 ETVSAEKAVAS-ATSETVSAGKADASEIVSAEKTDASETVSAEKADASETVSAEKPDASE 663
Query: 3285 CTAGSLLEKKDNVEVVIPSVKVRKKRDPASCSKTISSCKPRKASINKTNENLNMPSTQIN 3106
AG + + V + A+ S+T+S+ K + + + + +
Sbjct: 664 TEAGEKADASETVSAGKAATSETTSAGKAATSETVSAGKAATSETVSAEKAVTSETVSVE 723
Query: 3105 KQELAGVIVLSDNSDDAAVSKGKVKEANTVIKGAT------SSKKVKISSTGENSQERNS 2944
K + + VS K + TV T S++K S T + S
Sbjct: 724 KAATSETVSAEKADASETVSAEKTDASETVSGEKTDASETVSAEKADASETVSAEKTVAS 783
Query: 2943 FANDAALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQEESSGANDVAVNEKLKA 2764
++ K S+ + AT V +K S T + E + A++ EK A
Sbjct: 784 ATSETVSAEKAVTSETVSAEKAATSETVSAEKTDASETVSA---EKTDASETVSGEKTDA 840
Query: 2763 SDIEKGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATAINA 2584
S+ G T + +K + S V +K V EK + +V+ T +
Sbjct: 841 SETVSGEKTDASETVSAEKPDASETVSG---EKAVTSETESGEKAEASETVSGEKTDASE 897
Query: 2583 ATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSSEKKNIGNTLQALDEE 2404
T E T + + VE + T+ + K S+T S EK T + + E
Sbjct: 898 TTSAENGEKAATSETVSVEKADASETVSAE-----KAVTSETVSGEKAVASGTSETVSAE 952
Query: 2403 NKNVEVTIDRKIQGKGKRSESKTG-------SIPVMVAGCVNKASCEKFNQS---AKEFT 2254
+ T + + SE+ +G ++ A S EK + S + E
Sbjct: 953 KPDASETEVGEKTVVSEASETVSGEKTDASETVSAEKADASETVSAEKADASETVSAEKA 1012
Query: 2253 MSTDVLKDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTEINVAVFTEKGSI 2074
+++ + K + + + S +++ V + +A V + + V EK
Sbjct: 1013 DASETVSAGKAATSETVSAEKAVASATSETVSAEKTDASETVSAEKADASETVSAEKADA 1072
Query: 2073 SNTLHILEDINKKKEATNEEKLPEKGELSAELKPDSDSRSEFVATCVNEVSGQVNNLSIE 1894
S T ++ K AT+E EK + S + + + SE V+ + S V+ +
Sbjct: 1073 SET------VSAGKAATSETVSVEKTDASETVSGEKTATSETVSAGKTDASETVSAEKAD 1126
Query: 1893 EF-TMSRDRPEDAEIFKETVGTHQLEEKVGSTYAVPSGEKRDVNLILKEVVTAANDSNLT 1717
T+S ++ + +E + G E + A S E V+A + +T
Sbjct: 1127 ASETVSAEKTDASETV--SAGKAATSETTSAGKAATSETVSVEKAAASETVSA--EKAVT 1182
Query: 1716 EEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAG--TKSDTVGGRVDEMSGQGS 1543
E + A T++ V E A E EK + AG S+TV G E +
Sbjct: 1183 SETVSAEKAATSEPVSGEKTDASETVSAEKTATSETVSAGKAATSETVSG---EKTDASE 1239
Query: 1542 QLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDTNEAAVDDKINPEDMM---KKVDTA 1372
+S +K S V+V EK +++ + + +D +E +K + + K V +A
Sbjct: 1240 TVSAEKTVASETVSV-----EKTDASETISAEKADASETVSAEKADASETTSAEKTVASA 1294
Query: 1371 INDAIFTEKKIISNIIQISDDENKSTGITAEEN------MLEKGKLNSEIKTDRT----- 1225
++ + EK S + ++ + S ++AE+ +EK + + ++T
Sbjct: 1295 TSETVSGEKTDASETVS-AEKADASETVSAEKTDASETVSVEKVATSETVSAEKTVASAA 1353
Query: 1224 SEILAGRSDEERDQVSQFSTEELLMCSG---TVKDPNNFEKCSVSHRRQEQIGHKNDNAV 1054
E ++ + + VS T+ SG + + EK S ++
Sbjct: 1354 PETVSAEKTDASETVSGEKTDASETVSGEKAATSETVSAEKADTSETVSAGKADASETVS 1413
Query: 1053 IENLQAYAVNNCDTGAK-DGNFT---EKENASKIVSSLHEDIKCTTEVRIAGELH----- 901
E A A + + K D + T EK +AS+ VS+ T+E A +
Sbjct: 1414 AEKPVASATSETVSAEKADASETVSVEKTDASETVSAEKTVASATSETVSAEKADASETV 1473
Query: 900 --EKRDLKSEFKANTTL-------------ETVGG---CVNEKSRHVSQLSTEVLAMSSE 775
EK D A T+ ETV + S VS EVL
Sbjct: 1474 SGEKADASETVSAGKTVTSETVSAGKAAASETVSAEKTVASATSETVSGEKNEVLKNVLN 1533
Query: 774 MAEDAKVVGTDVVTYQ---LQEPSGDTNQVVV----DEAVNKDEAAAKDCPPTGDEKVGN 616
+AED + G +VT +++ DT V V +EA+ EA E++
Sbjct: 1534 VAEDTLITGGKLVTETFGIVKKKVADTWDVEVANPEEEALLVGEAVEDTVTSAELEQIRA 1593
Query: 615 IAYSLYEENIVKKETAIDEKMQEKWQLKAD----AASEIVARFVNEESGYA 475
L E I K E ++E K L D A S++ +N GYA
Sbjct: 1594 DILLLAEVAIEKNELLLEEGQAGKAVLVEDNTLAALSDMEVAAINARMGYA 1644
>gb|AAF15293.3| erythrocyte membrane-associated giant protein antigen 332 [Plasmodium
falciparum]
Length = 5458
Score = 120 bits (301), Expect = 4e-24
Identities = 216/1009 (21%), Positives = 437/1009 (43%), Gaps = 58/1009 (5%)
Frame = -3
Query: 2856 KDKEKVSHTSNISQEESSGANDVAVNEKLKASDI---EKGVDTTVKDANHTKKGNVSIMV 2686
K E+ S + I EE S + ++ V EK + +I EK V + ++ NVS +
Sbjct: 165 KPVEEKSVSEEIPVEEKSVSEEIPVEEKSVSEEIPVEEKNVSEEIP----VEEKNVSEEI 220
Query: 2685 GPIKQQKNVAKGISMNEKMKGKGSVAKNATAINAATHLEKKNIGNTLQA---------LD 2533
P+ ++KNV++ I + E+ + + ++ +E++N+ + +D
Sbjct: 221 -PV-EEKNVSEEIPVEEENVSE-EIPVEEENVSEEIPVEEENVSEEIPEGGIAIEDVPVD 277
Query: 2532 VENKNVEVTIEGKIQGKAKRSESKTCSSEKKNIGNTL--QALDEENKNVEVTIDRKIQGK 2359
E E+T++ KI K +E +T + E TL Q E + E I+ K +
Sbjct: 278 EETVTEEITVDEKIYDKLP-NEIETVNEEMPVEDETLTEQISSEHERVPEEIIEEKPFTE 336
Query: 2358 GKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDVLKDAKVFEKDVATHQL--EK 2185
G+ +ES T I + G V E+ Q E + ++ E+D+ ++ E
Sbjct: 337 GEETESLTDEI--VEEGVVTDDIPEE--QIITEKVQEEEEFVTGELSEEDIINEKVQEED 392
Query: 2184 GSGSNDVVIDKNINAKVAVEKVDTEINVAVFTEKGSISNTLHILEDIN---KKKEATNEE 2014
S + ++ + IN KV E+ E + GS++ + E +N + KE E
Sbjct: 393 ESVTEELPEEDIINEKVQEEE---ESAYQEIVQDGSVTKDVEYKELVNDDVRDKENFVIE 449
Query: 2013 KLPEKGELSAELKPDSDSRSEFVATCVNEVSGQV-NNLSIEEFTMSRDRP-EDAEIFKET 1840
+ P KG+L E P + EFV + V L+ E+ +++++ P E+ +FKE
Sbjct: 450 EDPFKGQLINEGLPVEE---EFVTKELPVKEESVFEELTEEDQSVTKEIPVEEHSVFKEV 506
Query: 1839 VGTHQLEEKVGSTYAVPSGEKRDVNLILKEVVTAANDSNLTEEKT--ISNTAHTADDVRK 1666
+ E++ E+ VN ++E V+ + + + TE T + T ++V K
Sbjct: 507 DEIESVTEEIVE-------EEGSVNEEVEEEVSVSGEVDETEYVTEEVEETELVNEEVLK 559
Query: 1665 EMEVAIEERMQEKGVSYS---EKKAGTKSDTVGGRVDEMSGQGSQLSTKKLAISSDVAVD 1495
E A E+ ++E+G + E++ +T + E G ++ S+ + + + +V
Sbjct: 560 EEGSASEKVVKEEGSASEKIVEEEGSVTEETASEEIVEEEGSVTEESSSEEIVEDEGSVT 619
Query: 1494 PKMFEKHASTDHLQEQISDTNEAA----VDDKINPEDMMKKVDTAINDAIFTEKKIISNI 1327
E+ +S + ++E+ S E+A V+D+++ + + + ++ + + E+ +S+
Sbjct: 620 ----EESSSEEIVEEEGSVIEESASEVIVEDEVSASKEIVEDEASVTEEVVEEEGAVSDE 675
Query: 1326 IQISD---DENKSTGITAEENMLEKGKLNSEIKTDRTSEILAGRSDEERDQVSQFST--E 1162
+Q+++ DE + GI E + ++ + EI + S I +E +V + + +
Sbjct: 676 VQVTESVEDEIINQGIVDEVIVEQEASVTDEIVKEDESVIEEIAVEETVTEVVEETKPMD 735
Query: 1161 ELLMCSGTVKDPNNFEKCSVSHRRQEQIGHKNDNAVIENLQAYAVNNCDTGAKDGNFTEK 982
E ++ G+V + N EK ++ +Q +V+EN++ + + G + G+ EK
Sbjct: 736 EEIVDQGSVVE-NVEEKKTMDEEIVDQ------GSVVENVEEKKTMDEEIGDQ-GSVAEK 787
Query: 981 ENASKIVS--------SLHEDI----KCTTEVR----IAGELHEKRDLKSEFKANTTLET 850
++V+ S++EDI T EV + G++ + + E K E
Sbjct: 788 VEEEELVTEEVIEREGSINEDIVKEASITEEVEQIEPVTGKVEKIESITDEIKEQLVPED 847
Query: 849 VGGCVNEKSRHVSQLST------EVLAMSSEMAEDAKVVGTDVVTYQLQEPSGDTNQVVV 688
+ + V+Q ++ EV +++ E+ E+ K V +V+ E G T + VV
Sbjct: 848 IKEEQLDFEEIVAQRASVNDEKVEVASITEEVEEEEKSVSEEVL-----EEEGSTTEKVV 902
Query: 687 DEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIV 508
+E + + E+ G+++ + EE E ++E+ +
Sbjct: 903 EEGSSTEVVV---------EEQGSVSEEVLEEEGSTTEEVVEEQ------------GSVT 941
Query: 507 ARFVNEESGYARQLPTEKLAMSTDTVGDYKISEKDIVSHLSQEQIHDKDEVVDETIHATD 328
+ EES + E+ D+V D + EK+ ++++ + ++ +++E
Sbjct: 942 ENLLEEESASQGIVEKEEFVDEEDSVKDQNVFEKE--GSVTEQLVEEEKGLINE------ 993
Query: 327 TVNKDETAATDDTLSEKEKENGNLKTECSVESTSAIAAGYARQLSTEELAMSTDIEE-DY 151
+ EKE L TE S E S LSTEE+ + ++
Sbjct: 994 ---------------DNEKEE--LITEMSEEIKSVNEEIEETDLSTEEIIKQQGLATYEF 1036
Query: 150 KISEKDIVSHLLQEQVHDKDEVVGETIHATDTVNKDETAATDDTLSEKE 4
EK + LL+E+ K+ VGET +T V ++ + T++ + E++
Sbjct: 1037 VEEEKSLTDKLLEEESVTKE--VGETELSTQEVVDEKVSVTEEVIEEEK 1083
Score = 117 bits (292), Expect = 5e-23
Identities = 234/1221 (19%), Positives = 497/1221 (40%), Gaps = 67/1221 (5%)
Frame = -3
Query: 3468 EKTGSVNQGVC--NLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKES--NVIVNVVI 3301
EK GSV++ + +S+S +E GS V E ++ + E ES IV +
Sbjct: 1549 EKVGSVSEEIIVEEVSASEEIVEE----GSVTEEVVEEEKLINEVGETESVTEEIVQKEV 1604
Query: 3300 GDNKKCTA--GSL----LEKKDNVEVVI-PSVKVRKKR-DPASCSKTISSCKPRKASINK 3145
D ++ GS+ LEK+ VE ++ P V ++ D S ++ + K + +
Sbjct: 1605 SDAEEVLGQEGSMNEEILEKESIVEEIVGPEGSVTEEIVDYGSFAEEV---KEEELVTEE 1661
Query: 3144 TNENLNMPSTQINKQELAGVIVLSDNSDDAAVSKGKVKEANTVIK--GATSSKKVKISST 2971
+ + +I ++E + S A + + K + ++K G + + V S
Sbjct: 1662 AVQYEGSVTEEIKEEESITENEAIEESAFAEIIEEKGPNNDEIVKEEGLDTEEIVNEVSV 1721
Query: 2970 GENSQERNSFANDAALNAKLQGSDKMKNTD-VATENCVLKDKEKVSHTSNISQEESSGAN 2794
+ E N+ + + ++K + ATE+ V +E S T +S E S
Sbjct: 1722 TDEVIEEEKLVNEQIVGEERSVTEKPVEVERSATEDLV---EEGASVTEKVSVHEGSTTE 1778
Query: 2793 DVAVNEKLKASDIEKGVDTTVK------DANHTKKGNVSIMVGPIKQQKNVAKGISMNEK 2632
+ ++E + +E+ V K + + S++ ++++++V + I + E+
Sbjct: 1779 QI-LDESVAEEIVEEEVSVDDKIIEEEVSVDEVVEEEGSVIEEIVEEEESVPEEI-LEEE 1836
Query: 2631 MKGKGSVAKNATAINAATHLEKKNIGNTLQALDVENKNVEVTIE-GKIQGKAKRSESKTC 2455
+ G V ++ +A E I + +D E E +E G K E
Sbjct: 1837 LSGSEEVLEDEWVTDAFMGQEGSVIEEIEEIVDGEGSITEEIVEDGSANEKIVEEEPSRV 1896
Query: 2454 SSEKKNIGNTLQALDEENKNVEVTIDRK-IQGKGKRSESKTGSIPVMVAGCVNKASCEKF 2278
G ++ + EE +E D K + K + S + V +++ EK
Sbjct: 1897 EEVLGKEGFVIEEIIEEGSVIEQVEDTKTVSEKSEESSAIEEVKEVKEEESISEKIVEKE 1956
Query: 2277 NQSAKEFTMSTD-----VLKDAK-----VFEKDVATHQLEKGSGSNDVV---IDKNINAK 2137
+E + ++KD V + D T ++ + GSN V +++ +A
Sbjct: 1957 ESVTEEIVRQEESTTEKIVKDVSPTEDFVEQTDSVTEKVIEQEGSNTEVAEDVEEKESAS 2016
Query: 2136 VAVEKVDTEINVAVFTEKGSISNTLHILEDINKKKEATNE-----EKLPEKGELSAELKP 1972
E+ D +N V EK S+ T I++++++ +E E E + E G ++ E+
Sbjct: 2017 DEHEQEDVSVNAQVTCEKKSV--TKEIVDEVSRTEEIVEENGSVTEGVDETGSVTEEIIE 2074
Query: 1971 DSDSRSEFVATCVNEVSGQVNNLSIEEFTMSRDRPEDAEIFKETVGTHQLEEKVGSTYAV 1792
++ E V G V +E+ ++ ++ ED + +E V ++ GS
Sbjct: 2075 EATVTEEVVE------DGSVTEEVVEDGSVIQEVVEDGSVTEEIV------QENGSVTEE 2122
Query: 1791 PSGEKRDVNLILKEVVTAANDSNLTEEKT--ISNTAHTADDVRKEMEVAIEERMQEKGVS 1618
E+ VN ++E V+ + + + TE T + +++ +E +EE ++E+G S
Sbjct: 2123 IVEEEGSVNEEVEEEVSVSGEVDETEYVTEEVEEEGSVVEEIVEEEGSVVEEIVEEEG-S 2181
Query: 1617 YSEKKAGTKSDTVGGRVDEMSGQGSQLSTKKLAISSDV-----AVDPKMFEKHAST--DH 1459
E+ + V V+E ++ ++ ++ ++ +V ++ E+ S +
Sbjct: 2182 VVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEI 2241
Query: 1458 LQEQISDTNEAAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQ----ISDDENKSTG 1291
++E+ S E ++ E+++++ + + + + E ++ I++ + ++ + G
Sbjct: 2242 VEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEG 2301
Query: 1290 ITAEENMLEKGKLNSEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEK 1111
EE + E+G + EI + S + EE VS+ E L+ V E+
Sbjct: 2302 SVVEEIVEEEGSVVEEIVEEEGSVV--EEIVEEEGSVSEVVDETELVNDEIV------EQ 2353
Query: 1110 CSVSHRRQEQIGHKNDNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCT 931
+ +EQ+ ND + + A AV ++ + + E+ ++ + E T
Sbjct: 2354 APFTEEVEEQVS-VNDEIIEDASVAEAVEESESITESVSQEEETEKGFVIEKVEETGAVT 2412
Query: 930 TEVRIAGELHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVV 751
E+ G + E+ +SE G +N++S L TE L + E+ A
Sbjct: 2413 EEIVQDGLITEEILEESE-------SVNGEIINKESDAEEILETEFL--TEEVVGQAGST 2463
Query: 750 GTDVV------TYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEEN 589
++V T +++E T ++V + +V ++ E+ G+IA + EE
Sbjct: 2464 SEEIVEEEGSVTKEVEEKESVTEELVDEGSVTEELVDEGSVTEEVVEQGGSIAQEIVEEE 2523
Query: 588 IVKKETAIDEKMQEKWQLKADAASEIVARFVNEESGYARQLPTEKLAMSTDTVGDYKISE 409
+E DE E+ V E+ G A TE++ D+ +
Sbjct: 2524 SATEEIIRDETNVEE---------------VLEKEGSA----TEEIVQDGSGTNDFVGKQ 2564
Query: 408 KDIVSHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVEST 229
++ +EVV+E I T+ K+E +A ++ + E+ L+ E+
Sbjct: 2565 GSVI-----------EEVVEEEISTTEEKLKEEASAIEEFVEEESIREDVLEESLVTENV 2613
Query: 228 SAIAAGYARQLSTEELAMSTDIEEDYK-------ISEKDIVSHLLQEQVHDKDEVVGETI 70
++ E + + DI E+ + + E+ + +++++ +E+V +
Sbjct: 2614 VGQQESVTEEIVDGEGSFTEDIVEEEESVTEEIVVDEESVTKEIVEDEELVTEEIVEDEG 2673
Query: 69 HATDTVNKDETAATDDTLSEK 7
T+ + +DE + T++ + E+
Sbjct: 2674 SFTEEIVEDEGSFTEEVIEER 2694
Score = 110 bits (276), Expect = 3e-21
Identities = 231/1279 (18%), Positives = 508/1279 (39%), Gaps = 126/1279 (9%)
Frame = -3
Query: 3468 EKTGSVNQGVCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNK 3289
E+ GSVN+ V S S +++ E VT E +V + + KE V+ +
Sbjct: 518 EEEGSVNEEVEEEVSVSGEVDETEY----VTEEVEETELVNEEVLKEEGSASEKVVKEEG 573
Query: 3288 KCTA------GSLLEKKDNVEVVIPSVKVRKKRDPASCSKTISSCKPRKASINKTNENLN 3127
+ GS+ E+ + E+V V ++ S S+ I + + + E +
Sbjct: 574 SASEKIVEEEGSVTEETASEEIVEEEGSVTEE----SSSEEIVEDEGSVTEESSSEEIVE 629
Query: 3126 MPSTQINKQELAGVIVLSDN--------SDDAAVSKGKVKEANTVIKGATSSKKVKISST 2971
+ I +E A +++ D D+A+V++ V+E V ++ V+
Sbjct: 630 EEGSVI--EESASEVIVEDEVSASKEIVEDEASVTEEVVEEEGAVSDEVQVTESVEDEII 687
Query: 2970 GENSQERNSFANDAALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQEESSGAND 2791
+ + +A++ ++ D+ ++A E V + E+ ++ S +
Sbjct: 688 NQGIVDEVIVEQEASVTDEIVKEDESVIEEIAVEETVTEVVEETKPMDEEIVDQGSVVEN 747
Query: 2790 VAVNEKLKASDIEKGVDTTVKDANHTKK-----GNVSIMVGPIKQQKNVAKGI-----SM 2641
V + + +++G + V++ K G+ + +++++ V + + S+
Sbjct: 748 VEEKKTMDEEIVDQG--SVVENVEEKKTMDEEIGDQGSVAEKVEEEELVTEEVIEREGSI 805
Query: 2640 NEKMKGKGSVAKNATAINAATHLEKK--NIGNTL--QALDVENKNVEVTIEGKIQGKAKR 2473
NE + + S+ + I T +K +I + + Q + + K ++ E + +A
Sbjct: 806 NEDIVKEASITEEVEQIEPVTGKVEKIESITDEIKEQLVPEDIKEEQLDFEEIVAQRASV 865
Query: 2472 SESKT--------CSSEKKNI--------GNTLQALDEENKNVEVTIDRK-------IQG 2362
++ K E+K++ G+T + + EE + EV ++ + ++
Sbjct: 866 NDEKVEVASITEEVEEEEKSVSEEVLEEEGSTTEKVVEEGSSTEVVVEEQGSVSEEVLEE 925
Query: 2361 KGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDVLKDAKVFEKDVATHQLEKG 2182
+G +E + + + S + +EF D +KD VFEK+ G
Sbjct: 926 EGSTTEEVVEEQGSVTENLLEEESASQGIVEKEEFVDEEDSVKDQNVFEKE--------G 977
Query: 2181 SGSNDVVIDKN--INAKVAVEKVDTEINVAVFTEKGSISNTLHILEDINKKKEATNEEKL 2008
S + +V ++ IN E++ TE++ + + I T E+I K++ E +
Sbjct: 978 SVTEQLVEEEKGLINEDNEKEELITEMSEEIKSVNEEIEETDLSTEEIIKQQGLATYEFV 1037
Query: 2007 PEKGELSAELKPDSDSRSEFVATCVNEVSGQVNNLSIEEFTMSRDRPEDAEIFKETVGTH 1828
E+ L+ +L + E T ++ +S+ E + ++ E+ +E T
Sbjct: 1038 EEEKSLTDKLLEEESVTKEVGETELSTQEVVDEKVSVTEEVIEEEKSVSEEVLEEGSATE 1097
Query: 1827 QLEEKVGSTYAVPSGEKRDVNLILKEVVTAANDSNLTEEKTISNTAHTADDVRKEM---E 1657
++ E+ GS + + D ++++E + + EE + + V +EM E
Sbjct: 1098 EVVEE-GSCTEIVVEKGSDTEIVVEE---GSATEIVVEEGSATEVVVEEGSVSEEMLEEE 1153
Query: 1656 VAIEERMQEKGVSYS--EKKAGTKSDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMF 1483
+ E + E+G+S +K G + G + + + +K+ + VD + F
Sbjct: 1154 GSATEEVVEEGLSSDNVQKSKGVIENV--GEIYSVKTAKDESMNEKIPLEKSSFVDDESF 1211
Query: 1482 EKHASTDHLQEQISDTNEAAVDDKINPEDMMK---------------------------- 1387
+ TD++ + D N + ++ P + K
Sbjct: 1212 KGQGPTDNVS--VEDVNSEDIINEHTPLEETKIEELPTEYITTADIHTRGETETKYNLIY 1269
Query: 1386 -KVDTAINDAIFTEKKIISNII----QISDD------------ENKSTGITAEENMLEKG 1258
K++ + A F E+KI NI +++D + +S EE L
Sbjct: 1270 EKINEEVEKAKFQEEKITENIPVERESVTEDIVQEPSLAQEVEQKESDTNEIEETKLANE 1329
Query: 1257 KLNSEIKTDRTSEILAGRSDEERDQVSQFSTEELL-----MCSGTVKDPNNFEKCSVSHR 1093
K+ E+ G EE + + TEE++ C V++ + + V
Sbjct: 1330 KIIPEVSVTENVVEKEGLDTEEVLEEDESITEEIVEEEVSACEEIVEEEESSSEEIVEEE 1389
Query: 1092 RQ--EQIGHKNDNAVIENLQAYAVNNCDTGAKDGNFTEK--ENASKIVSSLHEDIKCTTE 925
E+I + +++ E ++ ++ + ++ + +E+ E S L E+ T E
Sbjct: 1390 ESSSEEIVEEEESSSEEIVEEEESSSEEIVEEEESSSEEIIEEVSSTEEVLEEEGSVTEE 1449
Query: 924 V--RIAGELHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVV 751
+ E +D+ S + LE G E + E++ S + + V
Sbjct: 1450 IVEEEVSTTEEVKDIGSV--SEEVLEEEGFGTEEFVGQQGSVIEEIVETESSTEKVLEDV 1507
Query: 750 GTDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEENIVKKET 571
G++V ++ + G Q +V E V+ E + T +E V + S+ EE IV++ +
Sbjct: 1508 GSNVE--EIVQEEGPVAQEIVHEEVSTTEKHDEVDRSTTEEIVEKVG-SVSEEIIVEEVS 1564
Query: 570 AIDEKMQEKWQLKADAASEIVARFVNEESGYARQLPTEKLAMSTDTVG-----DYKISEK 406
A +E ++E + E + V E ++ ++++ + + +G + +I EK
Sbjct: 1565 ASEEIVEEGSVTEEVVEEEKLINEVGETESVTEEIVQKEVSDAEEVLGQEGSMNEEILEK 1624
Query: 405 D-IVSHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVEST 229
+ IV + + +E+VD A + K+E T++ + + +K E S+
Sbjct: 1625 ESIVEEIVGPEGSVTEEIVDYGSFAEEV--KEEELVTEEAVQYEGSVTEEIKEEESITEN 1682
Query: 228 SAIAAGYARQL------STEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIH 67
AI ++ + +E+ ++ + ++E + +++E+ +++VGE
Sbjct: 1683 EAIEESAFAEIIEEKGPNNDEIVKEEGLDTEEIVNEVSVTDEVIEEEKLVNEQIVGEERS 1742
Query: 66 ATDTVNKDETAATDDTLSE 10
T+ + E +AT+D + E
Sbjct: 1743 VTEKPVEVERSATEDLVEE 1761
Score = 110 bits (276), Expect = 3e-21
Identities = 246/1280 (19%), Positives = 506/1280 (39%), Gaps = 136/1280 (10%)
Frame = -3
Query: 3468 EKTGSVNQGVCNLSSSSTKI-------ENQENAGSTVTA-VRSENSMVTQGLEKESNVIV 3313
E+ GSVN+ V S S ++ E E GS V V E S+V + +E+E +V+
Sbjct: 2125 EEEGSVNEEVEEEVSVSGEVDETEYVTEEVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVE 2184
Query: 3312 NVVIGDNKKCTAGSLLEKKDNV--EVVIPSVKVRKKRDPASCSKTISSCKPRKASINKTN 3139
+V + + ++E++ +V E+V V ++ S + + + +
Sbjct: 2185 EIV--EEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIV 2242
Query: 3138 ENLNMPSTQINKQELAGVIVLSDNSDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENS 2959
E +I ++E G +V ++ +V + V+E +V++ + S E
Sbjct: 2243 EEEGSVVEEIVEEE--GSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEG---SVVEEIV 2297
Query: 2958 QERNSFANDAALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQ--EESSGANDVA 2785
+E S + ++ + V E V++ E V ++S+ +E+ ND
Sbjct: 2298 EEEGSVVEEI-----VEEEGSVVEEIVEEEGSVVE--EIVEEEGSVSEVVDETELVNDEI 2350
Query: 2784 VNEKLKASDIEKGV---DTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGS 2614
V + ++E+ V D ++DA+ + +++ +++ + +S E+ + KG
Sbjct: 2351 VEQAPFTEEVEEQVSVNDEIIEDAS---------VAEAVEESESITESVSQEEETE-KGF 2400
Query: 2613 VAKNATAINAATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSSEKKN- 2437
V + A T E G + + E+++V I K + E++ + E
Sbjct: 2401 VIEKVEETGAVTE-EIVQDGLITEEILEESESVNGEIINKESDAEEILETEFLTEEVVGQ 2459
Query: 2436 IGNTLQALDEENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEF 2257
G+T + + EE +V ++ K + + + + ++ G V + E+ A+E
Sbjct: 2460 AGSTSEEIVEEEGSVTKEVEEKESVTEELVDEGSVTEELVDEGSVTEEVVEQGGSIAQEI 2519
Query: 2256 ----TMSTDVLKDA----KVFEKD-VATHQL-EKGSGSNDVVIDKNINAKVAVEKVDTEI 2107
+ + ++++D +V EK+ AT ++ + GSG+ND V V E V+ EI
Sbjct: 2520 VEEESATEEIIRDETNVEEVLEKEGSATEEIVQDGSGTNDFV---GKQGSVIEEVVEEEI 2576
Query: 2106 NVAVFTEKGSISNTLHILEDINKKKEATNEEKLPEK--GELSAELKPDSDSRSEFVATCV 1933
+ K S +E+ + +++ E + E G+ + + D F V
Sbjct: 2577 STTEEKLKEEASAIEEFVEEESIREDVLEESLVTENVVGQQESVTEEIVDGEGSFTEDIV 2636
Query: 1932 NEVSGQVNNLSIEEFTMSRDRPEDAEIFKETVGTHQLEEKVGSTYAVPSGEKRDVNLILK 1753
E + ++E +++++ ED E+ E + +E++ T + E +++
Sbjct: 2637 EEEESVTEEIVVDEESVTKEIVEDEELVTEEI----VEDEGSFTEEIVEDEGSFTEEVIE 2692
Query: 1752 E--VVTAANDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYS-EKKAGTKSDT 1582
E ++ D+ EK + D + E +EE EK V+ E+K K +
Sbjct: 2693 ERSLIEEVEDTETVAEKEEGSVIKEIIDEKSLTEKIVEE---EKSVTEEVEEKESVKEEV 2749
Query: 1581 VGGR--VDEMSGQGSQLSTKKLA---ISSDVAVDPKMFEKHASTDHLQEQISDTNEAAVD 1417
R V+E + +LA I D+ V ++ E +TD EQ E +D
Sbjct: 2750 EEQRLVVEEEGSATEGIVEDRLATEGIVDDILVTEEIVEDGLATDEFVEQQGSIIEEVLD 2809
Query: 1416 DKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGITAEENMLEKGKLNSEIK 1237
D+ + + + + + + N+ I +I I + + E M+++G L +E+
Sbjct: 2810 DEGSVTEEIVEEEGSPNEEIVEGVSVIEEDDNIEPVSEEIVEGSVTEEMIKEG-LENEVI 2868
Query: 1236 TDR-------------------------TSEILAGRSDEERDQVSQFS-TEELLMCSGTV 1135
D T EI+ D + + S +EE++ V
Sbjct: 2869 LDEDSITEEALEKEGSVSEEIVEEMGSLTEEIVDEERSTSEDMIEEGSASEEIIQEESQV 2928
Query: 1134 KDPNNFEKCSVSHR--RQEQIGHKNDNAVIE-NLQAYAVNNCDTGAKDGNFTEKENASKI 964
++ E+ SV ++++ K IE N + + + G+ ++E +
Sbjct: 2929 EEV--VEEVSVIDEIVEEDELDTKEVVEEIEFNTEEVVEHKEEEGSVAEEIVQEEKEGSV 2986
Query: 963 VSSLHEDIKCTTEVRIA------GELHEKRDLKSEFKANTTLE--------------TVG 844
+ E++ TE + E+ E+R + E + N +E
Sbjct: 2987 NEEIIEEVGSITEEMVEQDVSDNEEIVEERSVIEEAEENVWIEKEVEEEGLDNEEVIDEE 3046
Query: 843 GCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVG---------------------TDVVTYQ 727
V+E++ ++ E+L SS++ ED KV ++ Y
Sbjct: 3047 DSVSEQAEEEVYINEEILKESSDV-EDVKVENELMNEEVNEETQSVAENNEEDKELDNYV 3105
Query: 726 LQEPSGDTNQVVVDEAVNKDEA---------AAKDCPPTGD-------------EKVGNI 613
++E T +VVVDE N E +D T D E+VG+
Sbjct: 3106 VEETESVTEEVVVDEVPNSKEVQEIESIIEEIVEDGLTTDDLVGQQGSVIEEVVEEVGSD 3165
Query: 612 AYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVA------RFVNEESGYARQLPTEKL 451
+ + EE + +E E + E ++ +I+ V EE + ++ TE+
Sbjct: 3166 SEGIVEEASITEEVEKKESVTEDILVEESVTGDILVEGSVTEEVVGEEKLVSEEIVTEEG 3225
Query: 450 AMSTDTVGD--YKISEKDIVSHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEK 277
+++ + V + E D + +++E + ++ V +E + +V +E + + E
Sbjct: 3226 SVAQEIVEEDAPATEEIDEIESVTEEVVEEEGPVDEEIVQEEGSVT-EEIIQGESKVEEV 3284
Query: 276 EKENGNLKTECSVESTSAIAAGYARQLSTEELAMSTDIEEDYKISEKDIVSHLLQEQVHD 97
+E G+ E VE SA + TEE+ ++ + + + +++EQ
Sbjct: 3285 VEEQGSENEEIFVEEVSASQEIVQNESGTEEILEKVSASQEI-VQDGSVTEQIIEEQKPV 3343
Query: 96 KDEVVGETIHATDTVNKDET 37
+EVV E T + ++E+
Sbjct: 3344 TEEVVNEEESITHEIIQEES 3363
Score = 109 bits (272), Expect = 1e-20
Identities = 239/1286 (18%), Positives = 509/1286 (39%), Gaps = 138/1286 (10%)
Frame = -3
Query: 3468 EKTGSVNQGVC--NLSSSSTKIENQENAGSTVTAVRS-----ENSMVTQGLEKESNVIVN 3310
E+ GS N+ + +S+S ++N+ + V + ++ VT+ + +E +
Sbjct: 3286 EEQGSENEEIFVEEVSASQEIVQNESGTEEILEKVSASQEIVQDGSVTEQIIEEQKPVTE 3345
Query: 3309 VVIGDNKKCTAGSLLEKKDNVEVVIPSVKVRKK--RDPASCSKTISSCKPRKASINKTNE 3136
V+ + + T +++++ +VE V+ V ++ +P S ++ I ++ S+ E
Sbjct: 3346 EVVNEEESITH-EIIQEESHVEKVVQQGSVAEEVVENPVSVTEEIVE---KEGSVT---E 3398
Query: 3135 NLNMPSTQINKQELAGVIVLSDNSDDAAVSKGKVKEANTVIKGATSSKK-VKISSTGENS 2959
++ +A IV + D+ + + + V +G + + V+ S E
Sbjct: 3399 DIGQEGY------VAEEIVEEEEFDNEEILEEESVAEEFVEEGFDNEEIFVEQISDSEIV 3452
Query: 2958 QERNSFANDAALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQEESSGANDVAVN 2779
+E NS N+ L + ++++ + + +L+ E+ S T I +EE S ++
Sbjct: 3453 KEENS-VNEEVLEEEGSYTEEILEEEGSYTEEILE--EEGSFTEEILEEEGSYNEEILEE 3509
Query: 2778 EKLKASDIEKGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNA 2599
E +I + + ++ + VG + + + S + G+GS+ +
Sbjct: 3510 EGSYNEEILEEEGSFTEEILEEEGSATDYFVGQGSDNEEIIEEGSATDYFVGQGSIIEEV 3569
Query: 2598 TAINAATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSSEKKNIGNTLQ 2419
LE++ + +T + + E E + +ES + ++ N +Q
Sbjct: 3570 --------LEEEGL-DTEKVFENEGSATEFEETESFTEVVEETESVNENILEETSINEVQ 3620
Query: 2418 ALDEENKNV-EVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTD 2242
++ +++ E + +I+ + SE + + + ++ KE + ++
Sbjct: 3621 KIESITEDIKEQLVPEEIKEEQLDSEE------------IKEEQLD--SEEIKEEQLDSE 3666
Query: 2241 VLKDAKVFEKDVATHQLEKGSGSNDVVIDKNI------NAKVAVEKVDTEINVAVFTEKG 2080
+K+ ++ +++ QL+ + ++ + I + ++ E++D+E +
Sbjct: 3667 EIKEEQLVPEEIKEEQLDSEEIKEEQLVPEEIKEEQLNSEEIKEEQLDSEEIKEEQLDSE 3726
Query: 2079 SISNTLHILEDINKKKEATNEEKLPEKGELSAELKPDSDSRSEFVATCVNE--------V 1924
I E+I ++K + NEE + E+G ++ E+K +S +E V V E V
Sbjct: 3727 EIKEEQLDSEEIKEQKGSVNEEVVEEEGSVTEEIKEQEESVNEEVLEEVEETESIKEEIV 3786
Query: 1923 SGQVNNLSI-----------EEFTMSRDRPEDA-----EIFKETVGTHQLEEKVGSTYAV 1792
G + I EE + ++ DA E+ E V + GST
Sbjct: 3787 EGGIATQEIIEEESDTKEVVEEEVIDSEKLVDAGSVTGEVMPEEVSVTDEVVEEGSTTEE 3846
Query: 1791 PSGEKRDVNLILKEVVTAANDSNLTEEKTISNTAHTADDVRKEMEVAIE---------ER 1639
E++ VN +EVV + LT + + T ++V +E AIE E
Sbjct: 3847 VLEEQKSVN---EEVV----EDGLTIDDFVGLQGSTTEEVVEEDGSAIEKILEEETATEE 3899
Query: 1638 MQEKGVSYSE---KKAGTKSDTV-------------GGRVDEMSGQGSQ----------L 1537
+ EK VS +E +K G+ ++ + G +E+ GQ L
Sbjct: 3900 IVEKQVSVTEDIVEKEGSVNEEIIEEASVAEEIIQGGSFTEEIVGQEESATEEVIDEEGL 3959
Query: 1536 STKKLAISSDVAVDPKMFE--KHASTDHLQEQISDTNEAA----VDDKINPEDMMKKVDT 1375
+ ++ + +V +M E + S D E++S E VDD+I PE++ D
Sbjct: 3960 ISNEIEEEEEKSVTEEMIEEVEEVSVDDEVEEVSVAEEIVEEELVDDEILPEELSATEDV 4019
Query: 1374 -----AINDAIFTEKKIISNII--------QISDDENKSTGITAEENMLEKGKLNSEIKT 1234
++ D I E+ + I+ + DD++ + E + + N+E T
Sbjct: 4020 IEEVRSVTDEIVQEESVCEEILEQEVSASEEYVDDKSVTDDFVGHERSVIQDVENTESVT 4079
Query: 1233 DRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKCSVSHRRQEQIGHKNDNAV 1054
+ +E+ +S E Q S E ++ + E SV+ EQ G D +
Sbjct: 4080 EEIAEV--DKSVIEEAVEKQGSVTEEIVEEEELDTEEVLEDKSVTGDVVEQEGSGKDESE 4137
Query: 1053 IENLQAYAVNNCDTGAKDGNFTEK-----ENASKIVSSLHEDIKCTTEV----RIAGELH 901
+ V+ + ++ TE E S +++ EV + ++
Sbjct: 4138 AKESFTEEVDELKSVKEEDQETEYISREIEEESATEQHSEQELSINKEVVETESLTKDIE 4197
Query: 900 EKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAE--------------- 766
E++ E T ++V + E+ R ++ E ++ S E+ E
Sbjct: 4198 EEKSTTQEILEET--QSVNEEIVEEERDTDEVLKEKVSPSEEVIEEQASTTEEFLEERSS 4255
Query: 765 -DAKVVGTDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEEN 589
D V D+ T +++E G + +V+E + E ++ G + + + E
Sbjct: 4256 TDEIVEVEDLFTEEVKEREGSVTEEIVEEGSDTGEIVEEE----GSDAEEILEEGSFNEE 4311
Query: 588 IVKKETAIDEKMQEKWQLKADAASEIVARFVNEESGYARQLPTEKLAMS---TDTVGDYK 418
IV++E +I E++ + + FV ++ ++ + A+ D +
Sbjct: 4312 IVEEEGSITEEILQ---------GSVTEEFVGQQGSVIEEIVETESAIEERVEDESATEE 4362
Query: 417 ISEKDIVSHLSQEQIHDKDEVVDETIH--------ATDTVNKDETAATDDTLSE-----K 277
+ E++ V+ + +E++ DEVV+ +I T+ + + E +A ++ + + +
Sbjct: 4363 VDERESVTEVVEEEVSSSDEVVEGSIEEVIENEGSVTEEILEHEVSADENFVGQAVSVIE 4422
Query: 276 EKENGNLKTECSVESTSAIAAGYARQLSTEELAMSTD--IEEDYKISEKDIVSHLLQEQV 103
E E TE VE T +++ TE + TD IEED + E + ++
Sbjct: 4423 EVEGTESVTEEVVEETESVSEEIVEVSPTENVVQQTDSVIEEDVEQKEGSFNEEIDIREL 4482
Query: 102 HDKDEVVGETIHATDTVNKDETAATD 25
D E I + V +D++A D
Sbjct: 4483 GDDGVEEREKISTEEVVGQDKSATGD 4508
Score = 107 bits (268), Expect = 3e-20
Identities = 229/1206 (18%), Positives = 501/1206 (41%), Gaps = 54/1206 (4%)
Frame = -3
Query: 3459 GSVNQGVCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNKKCT 3280
GSV + + SS+ K+ E+ GS V + E V Q + E V + + T
Sbjct: 1487 GSVIEEIVETESSTEKV--LEDVGSNVEEIVQEEGPVAQEIVHEE-VSTTEKHDEVDRST 1543
Query: 3279 AGSLLEKKDNVEVVIPSVKVRKKRDPASCSKTISSCKPRKASINKTNENLNMPSTQINKQ 3100
++EK +V I +V + + IN+ E ++ + K+
Sbjct: 1544 TEEIVEKVGSVSEEIIVEEVSASEEIVEEGSVTEEVVEEEKLINEVGETESVTEEIVQKE 1603
Query: 3099 --ELAGVIVLSDNSDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSFANDAA 2926
+ V+ + ++ + K + E +G+ + + V S E +E +A
Sbjct: 1604 VSDAEEVLGQEGSMNEEILEKESIVEEIVGPEGSVTEEIVDYGSFAEEVKEEELVTEEAV 1663
Query: 2925 LNAKLQGS--DKMKNTDVATENCVLKDKEKVSHTSNISQEESSGANDVAVNEKLKASDIE 2752
+ +GS +++K + TEN +++ S + I +E+ +++ E L +I
Sbjct: 1664 ---QYEGSVTEEIKEEESITENEAIEE----SAFAEIIEEKGPNNDEIVKEEGLDTEEIV 1716
Query: 2751 KGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATAINAATHL 2572
V T + K N I + ++++V + E+ + V + A+ +
Sbjct: 1717 NEVSVTDEVIEEEKLVNEQI----VGEERSVTEKPVEVERSATEDLVEEGASVTEKVSVH 1772
Query: 2571 EKKNIGNTL-QALDVENKNVEVTIEGKIQGKAKRSESKTCSSEKKNIGNTLQALDEENKN 2395
E L +++ E EV+++ KI E + + G+ ++ + EE ++
Sbjct: 1773 EGSTTEQILDESVAEEIVEEEVSVDDKII-----EEEVSVDEVVEEEGSVIEEIVEEEES 1827
Query: 2394 V-EVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDVLKDAKVF 2218
V E ++ ++ G + E + + M G E E +++ ++++D
Sbjct: 1828 VPEEILEEELSGSEEVLEDEWVTDAFM--GQEGSVIEEIEEIVDGEGSITEEIVEDGSAN 1885
Query: 2217 EKDVATH--QLEKGSGSNDVVIDKNINAKVAVEKVDTEINVAVFTEKGS-------ISNT 2065
EK V ++E+ G VI++ I +E+V+ V+ +E+ S +
Sbjct: 1886 EKIVEEEPSRVEEVLGKEGFVIEEIIEEGSVIEQVEDTKTVSEKSEESSAIEEVKEVKEE 1945
Query: 2064 LHILEDINKKKEATNEEKLPEKGELSAELKPDSDSRSEFVATCVNEVSGQVNNLSIEEFT 1885
I E I +K+E+ EE + ++ + ++ D +FV E + V IE+
Sbjct: 1946 ESISEKIVEKEESVTEEIVRQEESTTEKIVKDVSPTEDFV-----EQTDSVTEKVIEQEG 2000
Query: 1884 MSRDRPEDAEIFKETVGTHQLEEKVGSTYAVPSGEKRDVNLILKEVVTAAND---SNLTE 1714
+ + ED E + H+ E+ S A + EK+ V + + V+ + N +
Sbjct: 2001 SNTEVAEDVEEKESASDEHEQEDV--SVNAQVTCEKKSVTKEIVDEVSRTEEIVEENGSV 2058
Query: 1713 EKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAGTKSDTV--GGRVDEMSGQGSQ 1540
+ + T +++ +E V EE +++ V+ + G+ V G V E Q +
Sbjct: 2059 TEGVDETGSVTEEIIEEATVT-EEVVEDGSVTEEVVEDGSVIQEVVEDGSVTEEIVQENG 2117
Query: 1539 LSTKKLA---------ISSDVAVDPKMFEKHASTDHLQEQISDTNEAAVDDKINPEDMMK 1387
T+++ + +V+V ++ E T+ ++E+ S E ++ E++++
Sbjct: 2118 SVTEEIVEEEGSVNEEVEEEVSVSGEVDETEYVTEEVEEEGSVVEEIVEEEGSVVEEIVE 2177
Query: 1386 KVDTAINDAIFTEKKIISNIIQ----ISDDENKSTGITAEENMLEKGKLNSEIKTDRTSE 1219
+ + + + + E ++ I++ + ++ + G EE + E+G + EI + S
Sbjct: 2178 EEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSV 2237
Query: 1218 ILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKCSVSHRRQEQIGHKNDNAVIENLQ 1039
+ EE + EE++ G+V + E+ SV E+ G + V E
Sbjct: 2238 V------EEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGS 2291
Query: 1038 AYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCTTEVRIAGELHEKRDLKSEFKANTT 859
+ G+ E+E + +V + E+ E + E+ E+ SE T
Sbjct: 2292 VVEEIVEEEGSVVEEIVEEEGS--VVEEIVEE-----EGSVVEEIVEEEGSVSEVVDET- 2343
Query: 858 LETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVG----TDVVTYQLQEPSGDTNQVV 691
E V + E++ ++ +V +++ E+ EDA V ++ +T + + +T +
Sbjct: 2344 -ELVNDEIVEQAPFTEEVEEQV-SVNDEIIEDASVAEAVEESESITESVSQEE-ETEKGF 2400
Query: 690 VDEAVNKDEAAAKDCPPTG--DEKVGNIAYSLYEENIVKKETAIDEKMQEKWQLK----- 532
V E V + A ++ G E++ + S+ E I+ KE+ +E ++ ++ +
Sbjct: 2401 VIEKVEETGAVTEEIVQDGLITEEILEESESVNGE-IINKESDAEEILETEFLTEEVVGQ 2459
Query: 531 ADAASEIVARFVNEESGYARQLPTEKLAMSTDTVGDYKISEKDIVSHLSQEQIHDK---- 364
A + SE + EE G + EK +++ + V + ++E+ + E++ ++
Sbjct: 2460 AGSTSEEIV----EEEGSVTKEVEEKESVTEELVDEGSVTEELVDEGSVTEEVVEQGGSI 2515
Query: 363 -DEVVDETIHATDTVNKDETAATD-----DTLSEKEKENGNLKTECSVESTSAIAAGYAR 202
E+V+E AT+ + +DET + + +E+ ++G+ + + S I
Sbjct: 2516 AQEIVEEE-SATEEIIRDETNVEEVLEKEGSATEEIVQDGSGTNDFVGKQGSVIEEVVEE 2574
Query: 201 QLSTEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDTVNKDETAATDD 22
++ST E + + + E++ + + E+ + VVG+ T+ + E + T+D
Sbjct: 2575 EISTTEEKLKEEASAIEEFVEEESIREDVLEESLVTENVVGQQESVTEEIVDGEGSFTED 2634
Query: 21 TLSEKE 4
+ E+E
Sbjct: 2635 IVEEEE 2640
Score = 104 bits (260), Expect = 2e-19
Identities = 202/1083 (18%), Positives = 430/1083 (39%), Gaps = 57/1083 (5%)
Frame = -3
Query: 3102 QELAGVI--VLSDN--SDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSFAN 2935
QE+ +I ++ D +DD +G V E G+ S V+ +S E +++ S
Sbjct: 3128 QEIESIIEEIVEDGLTTDDLVGQQGSVIEEVVEEVGSDSEGIVEEASITEEVEKKESVTE 3187
Query: 2934 DAALNAKLQGSDKMKNTDVATENCVLKDK--EKVSHTSNISQEESSGANDVAVNEKLKAS 2761
D + + G D+ E V ++ E+ + I EE S A ++ +
Sbjct: 3188 DILVEESVTG-------DILVEGSVTEEVVGEEKLVSEEIVTEEGSVAQEIVEEDAPATE 3240
Query: 2760 DIEKGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATAINAA 2581
+I++ +++ ++ + GP+ ++ +G E ++G+ V +
Sbjct: 3241 EIDE-IESVTEEVVEEE--------GPVDEEIVQEEGSVTEEIIQGESKVEEVV------ 3285
Query: 2580 THLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSSEKKNIGNTLQALDEEN 2401
+ G+ + + VE + I G + E + S E G+ + + EE
Sbjct: 3286 -----EEQGSENEEIFVEEVSASQEIVQNESGTEEILEKVSASQEIVQDGSVTEQIIEEQ 3340
Query: 2400 K-------NVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTD 2242
K N E +I +I + E V N S + KE +++ D
Sbjct: 3341 KPVTEEVVNEEESITHEIIQEESHVEKVVQQGSVAEEVVENPVSVTE-EIVEKEGSVTED 3399
Query: 2241 VLKDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTEINVAVFTEKGSISNTL 2062
+ ++ V E+ V + + + +++ ++++ + E D E +F E+ S S
Sbjct: 3400 IGQEGYVAEEIVEEEEFD----NEEILEEESVAEEFVEEGFDNE---EIFVEQISDS--- 3449
Query: 2061 HILEDINKKKEATNEEKLPEKGELSAELKPDSDSRSEFVATCVNEVSGQVNNLSIEEFTM 1882
+I K++ + NEE L E+G + E+ + S +E + + E + EE +
Sbjct: 3450 ----EIVKEENSVNEEVLEEEGSYTEEILEEEGSYTEEI---LEEEGSFTEEILEEEGSY 3502
Query: 1881 SRDRPEDAEIFKETV------GTHQLEEKVGSTYAVPSGEKRDVNLILKE---------- 1750
+ + E+ + E + T ++ E+ GS G+ D I++E
Sbjct: 3503 NEEILEEEGSYNEEILEEEGSFTEEILEEEGSATDYFVGQGSDNEEIIEEGSATDYFVGQ 3562
Query: 1749 ---VVTAANDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAGTKSDTV 1579
+ + L EK N + E + E + + E+ + + +
Sbjct: 3563 GSIIEEVLEEEGLDTEKVFENEGSATEFEETESFTEVVEETESVNENILEETSINEVQKI 3622
Query: 1578 GGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDTNEAAVDDKINPE 1399
+++ Q K+ + S+ ++ E+ ++ ++E+ D+ E ++++ PE
Sbjct: 3623 ESITEDIKEQLVPEEIKEEQLDSE-----EIKEEQLDSEEIKEEQLDSEEIK-EEQLVPE 3676
Query: 1398 DMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGITAEENMLEKGKLNS-EIKTDR-- 1228
++ ++ Q+ +E K + EE +++ +LNS EIK ++
Sbjct: 3677 EIKEE--------------------QLDSEEIKEEQLVPEE--IKEEQLNSEEIKEEQLD 3714
Query: 1227 TSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKCSVSHRRQEQIGHKNDNAV-- 1054
+ EI + D E + Q +EE+ G+V + E+ SV+ +EQ N+ +
Sbjct: 3715 SEEIKEEQLDSEEIKEEQLDSEEIKEQKGSVNEEVVEEEGSVTEEIKEQEESVNEEVLEE 3774
Query: 1053 IENLQAYAVNNCDTGAKDGNFTEKENASK--IVSSLHEDIKCTTEVRIAGELHEKRDLKS 880
+E ++ + G E+E+ +K + + + K + GE+ +
Sbjct: 3775 VEETESIKEEIVEGGIATQEIIEEESDTKEVVEEEVIDSEKLVDAGSVTGEVMPE----- 3829
Query: 879 EFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVGTDV-----VTYQLQEP 715
+ + T E V E+ ++ E +++ E+ ED + V T ++ E
Sbjct: 3830 --EVSVTDEVV-----EEGSTTEEVLEEQKSVNEEVVEDGLTIDDFVGLQGSTTEEVVEE 3882
Query: 714 SGDTNQVVVDEAVNKDEAAAKDCPPTGD--EKVGNIAYSLYEENIVKKETAIDEKMQEKW 541
G + +++E +E K T D EK G++ + EE V +E E+
Sbjct: 3883 DGSAIEKILEEETATEEIVEKQVSVTEDIVEKEGSVNEEIIEEASVAEEIIQGGSFTEEI 3942
Query: 540 QLKADAASEIV----ARFVNEESGYARQLPTEKLAMSTDTVG-DYKISEKDIVSHLSQEQ 376
+ ++A+E V NE + TE++ + V D ++ E + + +E+
Sbjct: 3943 VGQEESATEEVIDEEGLISNEIEEEEEKSVTEEMIEEVEEVSVDDEVEEVSVAEEIVEEE 4002
Query: 375 IHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVESTSAIAAGYARQL 196
+ D DE++ E + AT+ V ++ + TD+ + E+ L+ E S
Sbjct: 4003 LVD-DEILPEELSATEDVIEEVRSVTDEIVQEESVCEEILEQEVSASEEYVDDKSVTDDF 4061
Query: 195 STEELAMSTDIEEDYKISE------KDIVSHLLQEQVHDKDEVVGETIHATDTVNKDETA 34
E ++ D+E ++E K ++ +++Q +E+V E T+ V +D++
Sbjct: 4062 VGHERSVIQDVENTESVTEEIAEVDKSVIEEAVEKQGSVTEEIVEEEELDTEEVLEDKSV 4121
Query: 33 ATD 25
D
Sbjct: 4122 TGD 4124
>ref|XP_002603167.1| hypothetical protein BRAFLDRAFT_63199 [Branchiostoma floridae]
gi|229288483|gb|EEN59178.1| hypothetical protein
BRAFLDRAFT_63199 [Branchiostoma floridae]
Length = 5785
Score = 119 bits (297), Expect = 1e-23
Identities = 238/1203 (19%), Positives = 440/1203 (36%), Gaps = 53/1203 (4%)
Frame = -3
Query: 3468 EKTGSVNQGVCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLE--KESNVIVN----- 3310
EKT S + S+ + + +E +TV ++ + LE KE +
Sbjct: 4541 EKTESTTEETVTEVSAKEETKREE---TTVEEAEKTETITEESLEIKKEQTEVATEEITT 4597
Query: 3309 -----VVIGDNKKCTAGSLLEKKDNVEVVIPSVKVRKKRDPASCSKTISSCKPRKASINK 3145
VV + + T +E K E V + K+ + + T + ++ +
Sbjct: 4598 EQTAAVVATEKTEVTTEERVENKK--EETTTEVSMTKEDTDTTENTTEETIAEEMTAVEE 4655
Query: 3144 TN--ENLNMPSTQINKQELAGVIVLSDNSDDAAVSKGKVKEANTVIKG----------AT 3001
T E +I K+E ++D S+ KG+ K+ T ++ +
Sbjct: 4656 TENTEIATKEEVEIKKEE-----TVTDKSEKEETKKGETKKEETTVEETEKTEAITEESA 4710
Query: 3000 SSKKVKISSTGENSQERNSFANDAALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNI 2821
+KK + T E + + A + K+ +K++ + T V KE+ T
Sbjct: 4711 ETKKEQTEVTKEETTTEETTAVEETKKTKVTTEEKVETKEEQTTTEVSMTKEETERTETK 4770
Query: 2820 SQE----ESSGANDVAVNEKLKASDIEKGVDTTVKDANHTKKGNVSIMVGPIKQ-QKNVA 2656
++E E + ++A E+++ E D + K+ TKKG +++ +K A
Sbjct: 4771 TEEMTAVEETENTEIATKEEVEIKKEETVTDKSEKE--ETKKGETKKEETTVEETEKTEA 4828
Query: 2655 KGISMNEKMKGKGSVAKNATAINAATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAK 2476
E K + V K T T +E E K +VT E K++ K +
Sbjct: 4829 ITEESAETKKEQTEVTKEETTTEETTAVE-------------ETKKTKVTTEEKVETKEE 4875
Query: 2475 RSESKTCSSEKKNIGNTLQALD----EENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAG 2308
++ ++ ++++ + + EE +N E+T K+ K + ++ +
Sbjct: 4876 QTTTEVSMTKEETERTETKTEEMTAVEETENTEITTKEKVDIKKEETKESEETKKEETMT 4935
Query: 2307 CVNKASCEKFNQSAKEFTMSTDVLKDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAV 2128
V+ EK +E T T+ EK T + + N+ + ++ +
Sbjct: 4936 EVSVKEEEKTETKKEETTSVTEA-------EKTEVTKEESVEAKINETATEVSVKEEEKT 4988
Query: 2127 EKVDTEINVAVFTEKGSISNTLHILEDINKKKEATNEEKLPEKGELSAELKPDSDSRSEF 1948
E E T+K T+ E + KKE T E ++ E + K ++ S +E
Sbjct: 4989 ENKTEETTAVKETKK--TEGTME--ESVETKKEETTTEVSVKEEEKTETKKEETTSVTEA 5044
Query: 1947 VATCVNEVSG-------QVNNLSIEEFTMSRDRPEDAEIFKETVGTHQLEEKVGST---- 1801
T V + +S++E + ED + +ET T +E+ T
Sbjct: 5045 EKTEVTKKDSVETKKEETTTEVSVKEEEKTETNKEDTAVVEETKKTEVTKEEKVETKKEE 5104
Query: 1800 ----YAVPSGEKRDVNLILKEVVTAANDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQ 1633
+V EK + VT A + +T+E+++ K+ E +
Sbjct: 5105 TTTEVSVKEEEKTETKKEETTAVTEAEKTQVTKEESVE---------AKKAETVAATEAE 5155
Query: 1632 EKGVSYSEKKAGTKSDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQ 1453
+ ++ + TK +TV V + + +KK + VA + K E + ++
Sbjct: 5156 KTELTTKQTVETTKEETVTVAVSVSQEEAEKTESKKT--ETTVAKETKKAEV-TKEEKVE 5212
Query: 1452 EQISDTNEAAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGITAEEN 1273
+ T E +V K ++ KK +TA A+ TE K + S + K +T EE
Sbjct: 5213 TKEETTTEVSVTQKETMKEETKKEETA---AVVTEAKETDVTTEDSVETQKDKTVTQEET 5269
Query: 1272 MLEKGKLNSEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKCSVSHR 1093
+ RT E +E + + +TEE+ T K E
Sbjct: 5270 --------EKAVATRTEETTVVEKADEDTKKEETTTEEIKAVEETKKTEEKVET------ 5315
Query: 1092 RQEQIGHKNDNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCTTEVRIA 913
++E+ + E+ + A T A++ + TE K +++ E T E +
Sbjct: 5316 KKEETSTEVSMTKEESEKTEAKKEETTVAEETDKTEAIIEEKAETTIEET---TAEKSVT 5372
Query: 912 GELHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQ-LSTEVLAMSS--EMAEDAKVVGTD 742
E +K D K + ET G EK + +TEV + E+ +V +
Sbjct: 5373 QEETKKTDTKKD-------ETTVGKETEKIEVAKEETATEVKKEDNVETKKEETALVQEN 5425
Query: 741 VVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGD-EKVGNIAYS-LYEENIVKKETA 568
T +E S +T V + K E ++ + EK + + E + ET
Sbjct: 5426 EKTEVTKEESQETKTEVSVKEEEKTETKTEETTVLKEAEKTTEVTKAESVETKKEETETE 5485
Query: 567 IDEKMQEKWQLKADAASEIVARFVNEESGYARQLPTEKLAMSTDTVGDYKISEKDIVSHL 388
+ K EK + K + + I EK ++ + + K E +
Sbjct: 5486 VSVKEDEKTETKKEETTAITE--------------AEKTEITKEESTETKKEETKTEVSV 5531
Query: 387 SQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVESTSAIAAGY 208
+QE++ + +ET +T E TD E +E T+ E T+
Sbjct: 5532 TQEEVEKTEAKTEETKVVAETKKTKEEKTTDTKKEETVEETKEEDTKTKEEETTV----- 5586
Query: 207 ARQLSTEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDTVNKDETAAT 28
TEE + +E+ ++KD E V + V E T+T NK+ET
Sbjct: 5587 -----TEETKNTEVTKEESVEAKKD-------EHVTEATSVTQEETEKTET-NKEETTIV 5633
Query: 27 DDT 19
+ T
Sbjct: 5634 EKT 5636
>gb|ETW56318.1| hypothetical protein PFUGPA_01683 [Plasmodium falciparum Palo
Alto/Uganda]
Length = 3312
Score = 118 bits (296), Expect = 2e-23
Identities = 237/1249 (18%), Positives = 504/1249 (40%), Gaps = 99/1249 (7%)
Frame = -3
Query: 3456 SVNQGVCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNKKCTA 3277
SV + + S + ++E +E+ + + E + + + E +V NVV + +
Sbjct: 1329 SVTEDIVQEPSLAQEVEQKESDTNEI----EETKLANEKIIPEVSVTENVV--EKEGLDT 1382
Query: 3276 GSLLEKKDNVEVVIPSVKVRKKRDPASCSKTISSCKPRKASINKTNENLNMPSTQINKQE 3097
+LE+ +++ I +V ++C + + + K+S + E S +I ++
Sbjct: 1383 EEVLEEDESITEEIVEEEV------SACEEIVEEEESSKSSSEEIVEEEESSSEEIIEEV 1436
Query: 3096 LAGVIVLSDNSDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSFANDAALNA 2917
++++ +G V E + +T+ + I S E E F + +
Sbjct: 1437 --------SSTEEVLEEEGSVTEEIVEEEVSTTEEVKDIGSVSEEVLEEEGFGTEEFVGQ 1488
Query: 2916 KLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQEESSGANDVAVNEKLKASDIEKGVDT 2737
+ +++ T+ +TE VL+D S+ I QEE A ++ V+E++ ++ VD
Sbjct: 1489 QGSVIEEIVETESSTEK-VLEDVG--SNVEEIVQEEGPVAQEI-VHEEVSTTEKHDEVDR 1544
Query: 2736 TVKDANHTKKGNVS--IMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATAINAATH-LEK 2566
+ + K G+VS I+V + + + + S+ E++ + + + T + +
Sbjct: 1545 STTEEIVEKVGSVSEEIIVEEVSASEEIVEEGSVTEEVVEEEKLINEVGETESVTEEIVQ 1604
Query: 2565 KNIGNTLQALDVENKNVEVTIE----------------------GKIQGKAKRSESKTCS 2452
K + + + L E E +E G + K E T
Sbjct: 1605 KEVSDAEEVLGQEGSMNEEILEKESIVEEIVGPEGSVTEEIVDHGSFAEEVKEEELVTEE 1664
Query: 2451 SEKKNIGNTLQALDEENKNVEVTIDRK-----IQGKGKRSESKTGSIPVMVAGCVNKASC 2287
+ + T + +EE+ I+ I+ KG ++ + VN+ S
Sbjct: 1665 AVQYEGSVTEEIKEEESITENEAIEESAFAEIIEEKGPNTDEIVKEEGLDTEEIVNEVSV 1724
Query: 2286 EKFNQSAKEFTMSTDVLKDAKVFEKDV-----ATHQL--------EKGSGSNDVVIDKNI 2146
++ V ++ V EK V AT L EK S ++ +
Sbjct: 1725 TDEVIEEEKLVNEQIVGEERSVTEKPVEVERSATEDLVEEEASVTEKVSVHEGSTTEQIL 1784
Query: 2145 NAKVAVEKVDTEINV--AVFTEKGSISNTLH----ILEDINKKKEATNEEKLPEKGELSA 1984
+ VA E V+ E++V + E+ S+ + ++E+I +++E+ EE L E+ S
Sbjct: 1785 DESVAEEIVEEEVSVDDKIIEEEVSVDEVVEEEGSVIEEIVEEEESVPEEILEEELSGSE 1844
Query: 1983 ELKPDSDSRSEFVATCVNEVSGQVNNLSIEEFTMSRDRPEDAEIFKETVGTH--QLEEKV 1810
E+ D F+ V ++ + E +++ + ED ++ V ++EE +
Sbjct: 1845 EVLEDEWVTDAFMGQ-EGSVIEEIEEIVDGEGSITEEIVEDGSANEKIVEEEPSRVEEVL 1903
Query: 1809 GSTYAVPSGEKRDVNLILKEVVTAANDSNLTEE-KTISNTAHTADDVRKEMEVAIEERMQ 1633
G +++E++ + E+ KT+S + + + + EV EE +
Sbjct: 1904 GKE-----------GFVIEEIIEEGSVIEQVEDTKTVSEKSEESSAIEEVKEVKEEESIS 1952
Query: 1632 EKGVSYSEKKAGTKSDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHAS-TDHL 1456
EK V E V E + + +T+K+ DV+ E+ S T+ +
Sbjct: 1953 EKIVEKEES------------VTEEIVRQEESTTEKIV--KDVSPTEDFVEQTDSVTEKV 1998
Query: 1455 QEQISDTNEAA--VDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGITA 1282
EQ E A V++K + D ++ D ++N + EKK ++ +I D+ +++ I
Sbjct: 1999 IEQEGSNTEVAEDVEEKESASDEHEQEDVSVNAQVTYEKKSVTK--EIVDEVSRTEEIVE 2056
Query: 1281 E---------------ENMLEKGKLNSEIKTDR--TSEILAGRSDEERDQVSQFSTEELL 1153
E E ++E+ + E+ D T E++ S + TEE++
Sbjct: 2057 ENGSVTEGVDETGSVTEEIIEEATVTEEVVEDGSVTEEVVEDGSVIQEVLEDGSVTEEIV 2116
Query: 1152 MCSGTVKDPNNFEKCSVSHRRQEQIG--HKNDNAVIENLQAYAVNNCDTGAKDGNFTEK- 982
+G+V + E+ SV+ +E++ + + +V E + V N D + FTE+
Sbjct: 2117 QENGSVTEEIVEEEGSVNEEVEEEVSVSGEEEGSVSEVVDETEVVN-DEIVEQAPFTEEV 2175
Query: 981 ENASKIVSSLHEDIKCTTEVRIAGELHEKRDLKSEFKANTTLETVG--GCVNEKSRHVSQ 808
E + + ED V + + E + E + +E V G V E+
Sbjct: 2176 EEQVSVNDEIIEDASVAEAVEESESITESVSQEEETEKGFVIEKVEETGAVTEEIVQDGL 2235
Query: 807 LSTEVLAMSSEM--------AEDAKVVGTDVVTYQLQEPSGDTNQVVVDEA------VNK 670
++ E+L S + ++ +++ T+ +T ++ +G T++ +V+E V +
Sbjct: 2236 ITEEILEESESVNGEIINKESDAEEILETEFLTEEVVGQAGSTSEEIVEEEGSVTKEVEE 2295
Query: 669 DEAAAKDCPPTGDEKVGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVARFVNE 490
E+ ++ G + E +V++ +I +++ E+ A EI+ N
Sbjct: 2296 KESVTEELVDEGSVTEELVDEGSVTEEVVEQGGSIAQEIVEE----ESATEEIIRDETNV 2351
Query: 489 ESGYARQ-LPTEKLAMSTDTVGDYKISEKDIVSHLSQEQIHDKDEVVDETIHATDTVNKD 313
E ++ TE++ D+ + ++ + +E+I +E + E A + ++
Sbjct: 2352 EEVLEKEGSATEEIVQDGSGTNDFVGKQGSVIEEVVEEEISTTEEKLKEEASAIEEFVEE 2411
Query: 312 ETAATDDTLSEKEKENGNLKTECSVESTSAIAAGYARQLSTEELAMSTDIEEDYKISEKD 133
E+ D EN + E E + + EE +++ +I D + K+
Sbjct: 2412 ESIREDVLEESLVTENVVGQQESVTEEIVDGEGSFTEDIVEEEESVTEEIVVDEESVTKE 2471
Query: 132 IVSH---LLQEQVHDK----DEVVGETIHATDTVNKDETAATDDTLSEK 7
IV + +E V D+ +E+V + T+ + +DE + T++ + E+
Sbjct: 2472 IVEDEELVTEEIVEDEGSFTEEIVEDEGSFTEEIVEDEGSFTEEVIEER 2520
Score = 111 bits (277), Expect = 3e-21
Identities = 212/1089 (19%), Positives = 437/1089 (40%), Gaps = 68/1089 (6%)
Frame = -3
Query: 3138 ENLNMPSTQINKQELAGVIVLSDNSDDAAVSKGKVKE--ANTVIKGATSSKKVKISSTGE 2965
E N+ + ++E ++ +N + +G +E + T ++ + E
Sbjct: 598 EKYNIEDMEETEKENEIEKIMDENKETEQTEEGNTEEFVQEKELNQETLENEIIVDHIKE 657
Query: 2964 NSQERNSFANDAALNAKLQGSDKMKNTDVATENCVLKDKEKVSH--------TSNISQEE 2809
RN ++ L ++ ++ EN + K E+V + +E
Sbjct: 658 EEDTRNVKEQESVL-------EESPIEELPVENNIGKINEEVEEFILNEIPLEEQVPKEL 710
Query: 2808 SSGANDVAVNEKLKASDIEKGVDTTVKDANHTKKGNVSIMVGPIKQ---QKNVAKGISMN 2638
+ V E+L + +TTV + + T KG + P+++ +K+V++ I +
Sbjct: 711 PQEEIEEIVVEELPIDEHLSSEETTVTEED-TFKGQLINEEKPVEEKIEEKSVSEEIPVE 769
Query: 2637 EKMKGKGSVAKNATAINAATHLEKKNIGNTLQALDVENKNV--EVTIEGKIQGKAKRSES 2464
EK +++ +E+KN+ + + VE KNV E+ +E K + E
Sbjct: 770 EK------------SVSEEIPVEEKNVS---EEIPVEEKNVSEEIPVEEKNVSEEIPVEE 814
Query: 2463 KTCSSEKKNIGNTLQ--ALDEENKNVEVTIDRKIQGK-GKRSESKTGSIPVMVAGCVNKA 2293
+ S E G ++ +DEE E+T+D KI K E+ +PV
Sbjct: 815 ENVSEEIPEGGIAIEDVPVDEETVTEEITVDEKIYDKLPNEIETVNEEMPVEDETLT--- 871
Query: 2292 SCEKFNQSAKEFTMSTDVLKDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDT 2113
Q + E + + + K F + T L VV D ++ EKV
Sbjct: 872 -----EQISSEHERVPEEIIEEKPFTEGEETESLTDEIVEEGVVTDDIPEEQIITEKVQE 926
Query: 2112 EINVAVFTEKGSISNTLHILEDINKKKEATNEEKLPEKGELSAELKPDSDSRSEFVATCV 1933
E G +S I+ + +++E+ +EE L E+G + E+ + S +E +
Sbjct: 927 EEEFVT----GELSEE-DIINEKVQEEESVSEEVLEEEGSTTEEVVEEQGSVTE---NLL 978
Query: 1932 NEVSGQVNNLSIEEFTMSRDRPEDAEIF-KETVGTHQL-EEKVGSTYAVPSGEKRDVNLI 1759
E S + EEF D +D +F KE T QL EE+ G EK ++
Sbjct: 979 EEESASQGIVEKEEFVDEEDSVKDQNVFEKEGSVTEQLVEEEKG--LINEDNEKEELITE 1036
Query: 1758 LKEVVTAAN----DSNLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAGTK 1591
+ E + + N +++L+ E+ I + +E + ++ ++E+ V+ K+ G
Sbjct: 1037 MSEEIKSVNEEIEETDLSTEEIIKQQGLATYEFVEEEKSLTDKLLEEESVT---KEVGET 1093
Query: 1590 SDTVGGRVDEMSGQGSQLSTKKLAISSDV----AVDPKMFEKHASTDHLQEQISDT---- 1435
+ VDE ++ ++ ++S +V + ++ E+ + T+ + E+ SDT
Sbjct: 1094 ELSTQEVVDEKVSVTEEVIEEEKSVSEEVLEEGSATEEVVEEGSCTEIVVEKGSDTEIVV 1153
Query: 1434 ---------------NEAAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENK 1300
E V++ E+M+++ +A + + E+ + S+ +Q S +
Sbjct: 1154 EEGSATEIVVEEGSATEVVVEEGSVSEEMLEEEGSATEEVV--EEGLSSDNVQKSKGVIE 1211
Query: 1299 STGITAEENMLEKGKLNSEIKTDRTS----EILAGRSDEERDQVSQFSTEELLMCSGTVK 1132
+ G + +N +I +++S E G+ + V ++E+++ T
Sbjct: 1212 NVGEIYSVKTAKDESMNEKIPLEKSSFVDDESFKGQGPTDNVSVEDVNSEDIIN-EHTPL 1270
Query: 1131 DPNNFEKCSVSHRRQEQIGHKNDNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSL 952
+ E+ + I K + NL +N AK EN S+
Sbjct: 1271 EETKIEELPTEYITTADIHTKGETETKYNLIYEKINEEVEKAKFQEEKITENIPVERESV 1330
Query: 951 HEDIKCTTEVRIAGELHEKRDLKSEF--------KANTTLETVGGCVNEKSRHVSQLSTE 796
EDI E +A E+ +K +E K + V ++ ++ E
Sbjct: 1331 TEDI--VQEPSLAQEVEQKESDTNEIEETKLANEKIIPEVSVTENVVEKEGLDTEEVLEE 1388
Query: 795 VLAMSSEMAEDAKVVGTDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGD--EKV 622
+++ E+ E+ ++V + +E S +++ +V+E + E ++ T + E+
Sbjct: 1389 DESITEEIVEEEVSACEEIV--EEEESSKSSSEEIVEEEESSSEEIIEEVSSTEEVLEEE 1446
Query: 621 GNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVARFVNEESGYARQLPTEKLAMS 442
G++ E IV++E + E+++ D S V+ V EE G+ + +
Sbjct: 1447 GSVT-----EEIVEEEVSTTEEVK-------DIGS--VSEEVLEEEGFGTEEFVGQQGSV 1492
Query: 441 TDTVGDYKISEKDIVSHLS---QEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEK 271
+ + + + S + ++ + +E + ++ V E +H + + T E +
Sbjct: 1493 IEEIVETESSTEKVLEDVGSNVEEIVQEEGPVAQEIVHEEVSTTEKHDEVDRSTTEEIVE 1552
Query: 270 ENGNLKTECSVESTSAIAAGYARQLSTEELAMSTDIEEDYKISE----KDIVSHLLQEQV 103
+ G++ E VE SA TEE+ +EE+ I+E + + ++Q++V
Sbjct: 1553 KVGSVSEEIIVEEVSASEEIVEEGSVTEEV-----VEEEKLINEVGETESVTEEIVQKEV 1607
Query: 102 HDKDEVVGE 76
D +EV+G+
Sbjct: 1608 SDAEEVLGQ 1616
Score = 107 bits (267), Expect = 4e-20
Identities = 206/1092 (18%), Positives = 437/1092 (40%), Gaps = 100/1092 (9%)
Frame = -3
Query: 2982 ISSTGENSQERNSFANDAALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQEESS 2803
+SS E ++F +N + +K++ V+ E V E+ S + I EE +
Sbjct: 729 LSSEETTVTEEDTFKGQL-INEEKPVEEKIEEKSVSEEIPV----EEKSVSEEIPVEEKN 783
Query: 2802 GANDVAVNEKLKASDI---EKGV--DTTVKDANHTKK---GNVSIMVGPIKQQKNVAKGI 2647
+ ++ V EK + +I EK V + V++ N +++ G ++I P+ ++ V + I
Sbjct: 784 VSEEIPVEEKNVSEEIPVEEKNVSEEIPVEEENVSEEIPEGGIAIEDVPVDEE-TVTEEI 842
Query: 2646 SMNEKMKGKGSVAKNATAINAATHLEKKNIGNTL------------------QALDVENK 2521
+++EK+ K + +N +E + + + + + E+
Sbjct: 843 TVDEKIYDK--LPNEIETVNEEMPVEDETLTEQISSEHERVPEEIIEEKPFTEGEETESL 900
Query: 2520 NVEVTIEGKIQGKAKRSESKTCSSEKKNIGNTLQALDEENKNVEVTIDRKIQGKGKRSES 2341
E+ EG + + T +++ T + +E+ N +V + + + E
Sbjct: 901 TDEIVEEGVVTDDIPEEQIITEKVQEEEEFVTGELSEEDIINEKVQEEESVSEEVLEEEG 960
Query: 2340 KTGSIPVMVAGCVNKASCEKFNQSA-----KEFTMSTDVLKDAKVFEKDVATHQLEKGSG 2176
T V G V + E+ + S +EF D +KD VFEK+ GS
Sbjct: 961 STTEEVVEEQGSVTENLLEEESASQGIVEKEEFVDEEDSVKDQNVFEKE--------GSV 1012
Query: 2175 SNDVVIDKN--INAKVAVEKVDTEINVAVFTEKGSISNTLHILEDINKKKEATNEEKLPE 2002
+ +V ++ IN E++ TE++ + + I T E+I K++ E + E
Sbjct: 1013 TEQLVEEEKGLINEDNEKEELITEMSEEIKSVNEEIEETDLSTEEIIKQQGLATYEFVEE 1072
Query: 2001 KGELSAELKPDSDSRSEFVATCVNEVSGQVNNLSIEEFTMSRDRPEDAEIFKETVGTHQL 1822
+ L+ +L + E T ++ +S+ E + ++ E+ +E T ++
Sbjct: 1073 EKSLTDKLLEEESVTKEVGETELSTQEVVDEKVSVTEEVIEEEKSVSEEVLEEGSATEEV 1132
Query: 1821 EEKVGSTYAVPSGEKRDVNLILKEVVTAANDSNLTEEKTISNTAHTADDVRKEM---EVA 1651
E+ GS + + D ++++E + + EE + + V +EM E +
Sbjct: 1133 VEE-GSCTEIVVEKGSDTEIVVEE---GSATEIVVEEGSATEVVVEEGSVSEEMLEEEGS 1188
Query: 1650 IEERMQEKGVSYS--EKKAGTKSDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEK 1477
E + E+G+S +K G + G + + + +K+ + VD + F+
Sbjct: 1189 ATEEVVEEGLSSDNVQKSKGVIENV--GEIYSVKTAKDESMNEKIPLEKSSFVDDESFKG 1246
Query: 1476 HASTDHLQEQISDTNEAAVDDKINPEDMMK-----------------------------K 1384
TD++ + D N + ++ P + K K
Sbjct: 1247 QGPTDNVS--VEDVNSEDIINEHTPLEETKIEELPTEYITTADIHTKGETETKYNLIYEK 1304
Query: 1383 VDTAINDAIFTEKKIISNII----QISDD------------ENKSTGITAEENMLEKGKL 1252
++ + A F E+KI NI +++D + +S EE L K+
Sbjct: 1305 INEEVEKAKFQEEKITENIPVERESVTEDIVQEPSLAQEVEQKESDTNEIEETKLANEKI 1364
Query: 1251 NSEIKTDRTSEILAGRSDEERDQVSQFSTEELL-----MCSGTVKDPNNFEKCSVSHRRQ 1087
E+ G EE + + TEE++ C V++ + + S +
Sbjct: 1365 IPEVSVTENVVEKEGLDTEEVLEEDESITEEIVEEEVSACEEIVEEEESSKSSSEEIVEE 1424
Query: 1086 EQIGHKNDNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCTTEVRIAGE 907
E+ + +IE + + + ++G+ TE+ + E++ T EV+ G
Sbjct: 1425 EE---SSSEEIIEEVSSTE----EVLEEEGSVTEE--------IVEEEVSTTEEVKDIGS 1469
Query: 906 LHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVGTDVVTYQ 727
+ E+ LE G E + E++ S + + VG++V +
Sbjct: 1470 VSEE-----------VLEEEGFGTEEFVGQQGSVIEEIVETESSTEKVLEDVGSNVE--E 1516
Query: 726 LQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEENIVKKETAIDEKMQE 547
+ + G Q +V E V+ E + T +E V + S+ EE IV++ +A +E ++E
Sbjct: 1517 IVQEEGPVAQEIVHEEVSTTEKHDEVDRSTTEEIVEKVG-SVSEEIIVEEVSASEEIVEE 1575
Query: 546 KWQLKADAASEIVARFVNEESGYARQLPTEKLAMSTDTVG-----DYKISEKD-IVSHLS 385
+ E + V E ++ ++++ + + +G + +I EK+ IV +
Sbjct: 1576 GSVTEEVVEEEKLINEVGETESVTEEIVQKEVSDAEEVLGQEGSMNEEILEKESIVEEIV 1635
Query: 384 QEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVESTSAIAAGYA 205
+ +E+VD A + K+E T++ + + +K E S+ AI
Sbjct: 1636 GPEGSVTEEIVDHGSFAEEV--KEEELVTEEAVQYEGSVTEEIKEEESITENEAIEESAF 1693
Query: 204 RQL------STEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDTVNKD 43
++ +T+E+ ++ + ++E + +++E+ +++VGE T+ +
Sbjct: 1694 AEIIEEKGPNTDEIVKEEGLDTEEIVNEVSVTDEVIEEEKLVNEQIVGEERSVTEKPVEV 1753
Query: 42 ETAATDDTLSEK 7
E +AT+D + E+
Sbjct: 1754 ERSATEDLVEEE 1765
Score = 106 bits (264), Expect = 8e-20
Identities = 251/1299 (19%), Positives = 507/1299 (39%), Gaps = 158/1299 (12%)
Frame = -3
Query: 3459 GSVNQGVCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNKKCT 3280
GSV + V + + S K E + +A V V+ E S+ + +EKE +V +V + T
Sbjct: 1917 GSVIEQVEDTKTVSEKSE-ESSAIEEVKEVKEEESISEKIVEKEESVTEEIV-RQEESTT 1974
Query: 3279 AGSLLEKKDNVEVVIPSVKVRKKRDPASCSKT-ISSCKPRKASINKTNE----NLNMPST 3115
+ + + V + V +K S T ++ K S + +E ++N T
Sbjct: 1975 EKIVKDVSPTEDFVEQTDSVTEKVIEQEGSNTEVAEDVEEKESASDEHEQEDVSVNAQVT 2034
Query: 3114 QINKQELAGVIVLSDNSDDAAVSKGKVKEA--------NTVIKGATSSKKV-KISSTGEN 2962
K ++ +++ G V E +I+ AT +++V + S E
Sbjct: 2035 YEKKSVTKEIVDEVSRTEEIVEENGSVTEGVDETGSVTEEIIEEATVTEEVVEDGSVTEE 2094
Query: 2961 SQERNSFANDAALNAKLQGSDKMKNTDVATENCVLKD---KEKVSHTSNISQEESSGAND 2791
E S + + + +N V TE V ++ E+V ++S EE ++
Sbjct: 2095 VVEDGSVIQEVLEDGSVTEEIVQENGSV-TEEIVEEEGSVNEEVEEEVSVSGEEEGSVSE 2153
Query: 2790 VA-----VNEKLK-----ASDIEKGV---DTTVKDANHTKKGNVSIMVGPIKQQKNVAKG 2650
V VN+++ ++E+ V D ++DA+ + +++ +++ +
Sbjct: 2154 VVDETEVVNDEIVEQAPFTEEVEEQVSVNDEIIEDAS---------VAEAVEESESITES 2204
Query: 2649 ISMNEKMKGKGSVAKNATAINAATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRS 2470
+S E+ + KG V + A T E G + + E+++V I K +
Sbjct: 2205 VSQEEETE-KGFVIEKVEETGAVTE-EIVQDGLITEEILEESESVNGEIINKESDAEEIL 2262
Query: 2469 ESKTCSSEKKN-IGNTLQALDEENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKA 2293
E++ + E G+T + + EE +V ++ K + + + + ++ G V +
Sbjct: 2263 ETEFLTEEVVGQAGSTSEEIVEEEGSVTKEVEEKESVTEELVDEGSVTEELVDEGSVTEE 2322
Query: 2292 SCEKFNQSAKEF----TMSTDVLKDA----KVFEKD-VATHQL-EKGSGSNDVVIDKNIN 2143
E+ A+E + + ++++D +V EK+ AT ++ + GSG+ND V
Sbjct: 2323 VVEQGGSIAQEIVEEESATEEIIRDETNVEEVLEKEGSATEEIVQDGSGTNDFV---GKQ 2379
Query: 2142 AKVAVEKVDTEINVAVFTEKGSISNTLHILEDINKKKEATNEEKLPEK--GELSAELKPD 1969
V E V+ EI+ K S +E+ + +++ E + E G+ + +
Sbjct: 2380 GSVIEEVVEEEISTTEEKLKEEASAIEEFVEEESIREDVLEESLVTENVVGQQESVTEEI 2439
Query: 1968 SDSRSEFVATCVNEVSGQVNNLSIEEFTMSRDRPEDAEIFKETVG------THQLEEKVG 1807
D F V E + ++E +++++ ED E+ E + T ++ E G
Sbjct: 2440 VDGEGSFTEDIVEEEESVTEEIVVDEESVTKEIVEDEELVTEEIVEDEGSFTEEIVEDEG 2499
Query: 1806 S-TYAVPSGEKRDVNLILKE--VVTAANDSNLTEEKTISNTAHTADDVRKEMEVAIEERM 1636
S T + E +++E ++ D+ EK + D + E +EE
Sbjct: 2500 SFTEEIVEDEGSFTEEVIEERSLIEEVEDTETVAEKEEGSVIKEIIDEKSLTEKIVEE-- 2557
Query: 1635 QEKGVSYS-EKKAGTKSDTVGGR--VDEMSGQGSQLSTKKLA---ISSDVAVDPKMFEKH 1474
EK V+ E+K K + R V+E + +LA I D+ V ++ E
Sbjct: 2558 -EKSVTEEVEEKESVKEEVEEQRLVVEEEGSATEGIVEDRLATEGIVDDILVTEEIVEDG 2616
Query: 1473 ASTDHLQEQISDTNEAAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKST 1294
+TD E E +DD+ + + + + + + N+ I +I I +
Sbjct: 2617 LATDEFVEHQGSIIEEVLDDEGSVTEEIVEEEGSPNEEIVEGVSVIEEDDNIEPVSEEIV 2676
Query: 1293 GITAEENMLEKGKLNSEIKTDR-------------------------TSEILAGRSDEER 1189
+ E M+++G L +E+ D T EI+
Sbjct: 2677 EGSVTEEMIKEG-LENEVILDEDSITEEALEKEGSVSEEIVEEMGSLTEEIVDEERSTSE 2735
Query: 1188 DQVSQFS-TEELLMCSGTVKDPNNFEKCSVSHR--RQEQIGHKNDNAVIE-NLQAYAVNN 1021
D + + S +EE++ V++ E+ SV ++++ K IE N + +
Sbjct: 2736 DMIEEGSASEEIIQEESQVEEV--VEEVSVIDEIVEEDELDTKEVVEEIEFNTEEVVEHK 2793
Query: 1020 CDTGAKDGNFTEKENASKIVSSLHEDIKCTTEVRIA------GELHEKRDLKSEFKANTT 859
+ G+ ++E + + E++ TE + E+ E+R + E + N
Sbjct: 2794 EEEGSVAEEIVQEEKEGSVNEEIIEEVGSITEEMVEQDVSDNEEIVEERSVIEEAEENVW 2853
Query: 858 LE--------------TVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVG--------- 748
+E V+E++ ++ E+L SS++ ED KV
Sbjct: 2854 IEKEVEEEGLDNEEVIDEEDSVSEQAEEEVYINEEILKESSDV-EDVKVENELMNEEVNE 2912
Query: 747 ------------TDVVTYQLQEPSGDTNQVVVDEAVNKDEA---------AAKDCPPTGD 631
++ Y ++E T +VVVDE N E +D T D
Sbjct: 2913 ETQSVAENNEEDKELDNYVVEETESVTEEVVVDEVPNSKEVQEIESIIEEIVEDGLTTDD 2972
Query: 630 -------------EKVGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVA----- 505
E+VG+ + + EE + +E E + E ++ +I+
Sbjct: 2973 LVGQQGSVIEEVVEEVGSDSEEIVEEASITEEVEKKESVTEDILVEESVTGDILVEGSVT 3032
Query: 504 -RFVNEESGYARQLPTEKLAMSTDTVGD--YKISEKDIVSHLSQEQIHDKDEVVDETIHA 334
V EE + ++ TE+ +++ + V + E D + +++E + ++ V +E +
Sbjct: 3033 EEVVGEEKLVSEEIVTEEGSVAQEIVEEDAPATEEIDEIESVTEEVVEEEGPVDEEIVQE 3092
Query: 333 TDTVNKDETAATDDTLSEKEKENGNLKTECSVESTSAIAAGYARQLSTEELAMSTDIEED 154
+V +E + + E +E G+ E VE SA + TEE+ ++
Sbjct: 3093 EGSVT-EEIIQGESKVEEVVEEQGSENEEIFVEEVSASQEIVQNESGTEEILEKVSASQE 3151
Query: 153 YKISEKDIVSHLLQEQVHDKDEVVGETIHATDTVNKDET 37
+ + + +++EQ +EVV E T + ++E+
Sbjct: 3152 I-VQDGSVTEQIIEEQKPVTEEVVNEEESITHEIIQEES 3189
Score = 76.6 bits (187), Expect = 7e-11
Identities = 160/738 (21%), Positives = 296/738 (40%), Gaps = 44/738 (5%)
Frame = -3
Query: 2088 EKGSISNTLHILEDINKKKEATNE---EKLPEKGELSAE----------LKPDSDSRSEF 1948
E+ N + + D NK+ E T E E+ ++ EL+ E +K + D+R+
Sbjct: 606 EETEKENEIEKIMDENKETEQTEEGNTEEFVQEKELNQETLENEIIVDHIKEEEDTRN-- 663
Query: 1947 VATCVNEVSGQVNNLSIEEFTMSRDRPEDAEIFKETVGTH-QLEEKVGSTYAVPSGEKRD 1771
V E + IEE + + + E +E + LEE+V +P E +
Sbjct: 664 ----VKEQESVLEESPIEELPVENNIGKINEEVEEFILNEIPLEEQVPKE--LPQEEIEE 717
Query: 1770 VNLILKEVVTAANDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAGTK 1591
+ +++E+ D +L+ E+T T E +EE+++EK VS
Sbjct: 718 I--VVEELPI---DEHLSSEETTVTEEDTFKGQLINEEKPVEEKIEEKSVS--------- 763
Query: 1590 SDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDTNEAAVDDK 1411
++ ++ ++S ++ V+ EK+ S + E+ + + E V++K
Sbjct: 764 ---------------EEIPVEEKSVSEEIPVE----EKNVSEEIPVEEKNVSEEIPVEEK 804
Query: 1410 INPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGITAEENMLEKGKLNSEIKTD 1231
+++ I E++ +S +E GI E+ +++ + EI D
Sbjct: 805 ------------NVSEEIPVEEENVS-------EEIPEGGIAIEDVPVDEETVTEEITVD 845
Query: 1230 RTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKCSVSHRRQEQIGHKNDNAVI 1051
E + + E + V+ EE+ V+D E+ S H R + +I
Sbjct: 846 ---EKIYDKLPNEIETVN----EEM-----PVEDETLTEQISSEHERVPE-------EII 886
Query: 1050 ENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCTTEVRIAGELHEKRDLKSEFK 871
E + FTE E + + E+ T ++ + EK + EF
Sbjct: 887 E---------------EKPFTEGEETESLTDEIVEEGVVTDDIPEEQIITEKVQEEEEFV 931
Query: 870 ANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVGTDVVTYQLQEPSGDTNQVV 691
E +NEK + +S EVL E+ V VT L E + +V
Sbjct: 932 TGELSEE--DIINEKVQEEESVSEEVLEEEGSTTEEV-VEEQGSVTENLLEEESASQGIV 988
Query: 690 VDEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEI 511
E +E + KD EK G++ E +V++E + + EK +L + + EI
Sbjct: 989 EKEEFVDEEDSVKD--QNVFEKEGSVT-----EQLVEEEKGLINEDNEKEELITEMSEEI 1041
Query: 510 VARFVNEESGYARQLPTEKLAMSTDTVGDYKISEKDIVSHLSQEQIHDKD---------E 358
+ VNEE E + ++ EK + L +E+ K+ E
Sbjct: 1042 --KSVNEEIEETDLSTEEIIKQQGLATYEFVEEEKSLTDKLLEEESVTKEVGETELSTQE 1099
Query: 357 VVDETIHATDTVNKDETAATDDTL-----SEKEKENGNLKTECSVESTS----AIAAGYA 205
VVDE + T+ V ++E + +++ L +E+ E G+ TE VE S + G A
Sbjct: 1100 VVDEKVSVTEEVIEEEKSVSEEVLEEGSATEEVVEEGSC-TEIVVEKGSDTEIVVEEGSA 1158
Query: 204 RQLSTEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDTVNKDE----- 40
++ EE + + + E+ +SE+ +L+E+ +EVV E + ++D V K +
Sbjct: 1159 TEIVVEEGSATEVVVEEGSVSEE-----MLEEEGSATEEVVEEGL-SSDNVQKSKGVIEN 1212
Query: 39 -------TAATDDTLSEK 7
A D++++EK
Sbjct: 1213 VGEIYSVKTAKDESMNEK 1230
Score = 65.1 bits (157), Expect = 2e-07
Identities = 137/681 (20%), Positives = 268/681 (39%), Gaps = 20/681 (2%)
Frame = -3
Query: 1983 ELKPDSDSRSEFVATCVNEVSGQVNNLSIEEFTMSRDRP-----EDAEIFKETVGT-HQL 1822
E P+++S + + E + +SIE + RD+ E+ ++ KE V +
Sbjct: 410 EYSPETESANSKIKPTYEENDEDKSKISIETSEIDRDKEPFRISEEKKVVKEDVQELENI 469
Query: 1821 EEKVGSTYAV-PSGEKRDVNLILKEVVTAANDSNLTEEKTISNTAHTADDVRKEMEVAIE 1645
E + T+ KR+++ I K++ + I + + ++E + IE
Sbjct: 470 EYEFDETFDFFDEDAKRNIDDIRKDI-----------QSQIMKSVENYNSEKEEFKRNIE 518
Query: 1644 ERMQEKGVSYSEKKAGTKSDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHAST 1465
++ E G + AG S + E+ + + + + V + KH+
Sbjct: 519 TQLIESGDGMN---AGNYSSALQDNSTEIPTMVLVPGVLTVFLLTIIWV---LVYKHSLI 572
Query: 1464 DHLQEQISDTNEAAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGIT 1285
D + E + + + E +K + I D TEK+ N I+ DENK T T
Sbjct: 573 DRVHGTGKTKKEEKMKELESEEFPKEKYN--IEDMEETEKE---NEIEKIMDENKETEQT 627
Query: 1284 AE---ENMLEKGKLNSEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFE 1114
E E +++ +LN E + EI+ EE D + E +L + + E
Sbjct: 628 EEGNTEEFVQEKELNQETLEN---EIIVDHIKEEEDTRNVKEQESVL-------EESPIE 677
Query: 1113 KCSVSHRRQEQIGHKNDNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSS------- 955
+ V + N + E ++ + +N + +E +IV
Sbjct: 678 ELPVEN---------NIGKINEEVEEFILNEIPLEEQVPKELPQEEIEEIVVEELPIDEH 728
Query: 954 -LHEDIKCTTEVRIAGEL-HEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMS 781
E+ T E G+L +E++ ++ + + + E + V EKS ++ E +S
Sbjct: 729 LSSEETTVTEEDTFKGQLINEEKPVEEKIEEKSVSEEIP--VEEKSVS-EEIPVEEKNVS 785
Query: 780 SEMAEDAKVVGTDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYSL 601
E+ + K V ++ P + N V E + +E + P G + ++
Sbjct: 786 EEIPVEEKNVSEEI-------PVEEKN---VSEEIPVEEENVSEEIPEGGIAIEDVPV-- 833
Query: 600 YEENIVKKETAIDEKMQEKWQLKADAASEIVARFVNEESGYARQLPTEKLAMSTDTVGDY 421
+E V +E +DEK+ +K + + VNEE + TE+++ + V +
Sbjct: 834 -DEETVTEEITVDEKIYDKLPNEIET--------VNEEMPVEDETLTEQISSEHERVPEE 884
Query: 420 KISEKDIVSHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECS 241
I EK E + DE+V+E + TD + +E T+ E+E G L E
Sbjct: 885 IIEEKPFTEGEETESL--TDEIVEEGV-VTDDI-PEEQIITEKVQEEEEFVTGELSEEDI 940
Query: 240 VESTSAIAAGYARQLSTEELAMSTDI-EEDYKISEKDIVSHLLQEQVHDKDEVVGETIHA 64
+ + ++ EE + + ++ EE ++E + + + +K+E V E
Sbjct: 941 INEKVQEEESVSEEVLEEEGSTTEEVVEEQGSVTENLLEEESASQGIVEKEEFVDEEDSV 1000
Query: 63 TDTVNKDETAATDDTLSEKEK 1
D ++ + + L E+EK
Sbjct: 1001 KDQNVFEKEGSVTEQLVEEEK 1021
>gb|ETW30239.1| hypothetical protein PFFCH_02322 [Plasmodium falciparum FCH/4]
Length = 3761
Score = 118 bits (295), Expect = 2e-23
Identities = 208/993 (20%), Positives = 414/993 (41%), Gaps = 66/993 (6%)
Frame = -3
Query: 2784 VNEKLKASDIEKGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNE------KMKG 2623
+ E K ++IEK +D K+ T++GN V Q+K + + NE K +
Sbjct: 605 MEETEKENEIEKIMDEN-KETEQTEEGNTEEFV----QEKELNQETLENEIIVDHIKEEE 659
Query: 2622 KGSVAKNATAINAATHLEKKNIGNTLQALDVENKNV---EVTIEGKIQGKAKRSESKTCS 2452
K ++ + +E+ + N + ++ E + E+ +E ++ + + E +
Sbjct: 660 DTRNVKEQESVLEESPIEELPVENNIGKINEEVEEFILNEIPLEEQVPKELPQEEIEEIV 719
Query: 2451 SEKKNI---GNTLQ--ALDEENKNVEVTIDRKIQGK-GKRSESKTGSIPVMVAGCVNKAS 2290
E + I G ++ +DEE E+T+D KI K E+ +PV
Sbjct: 720 VEDEEIPEGGIAIEDVPVDEETVTEEITVDEKIYDKLPNEIETVNEEMPVEDETLT---- 775
Query: 2289 CEKFNQSAKEFTMSTDVLKDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTE 2110
Q + E + + + K F + T L VV D ++ EKV E
Sbjct: 776 ----EQISSEHERVPEEIIEEKPFTEGEETESLTDEIVEEGVVTDDIPEEQIITEKVQEE 831
Query: 2109 -------------INVAVFTEKGSISNTLHILEDINKKKEATNE---EKLPEKGELSAEL 1978
IN V E S++ L + IN+K + E +++ + G ++ ++
Sbjct: 832 EEFVTGELSEEDIINEKVQEEDESVTEELPEEDIINEKVQEEEESAYQEIVQDGSVTKDV 891
Query: 1977 K------PDSDSRSEFVATCVNEVSGQVNN--LSIEEFTMSRDRPEDAEIFKETVGTHQL 1822
+ D + FV + GQ+ N L +EE ++++ P + +E+V
Sbjct: 892 EYKELVNDDVRDKENFVIE-EDPFKGQLINEGLPVEEEFVTKELP----VKEESVFEELT 946
Query: 1821 EEKVGSTYAVPSGEKRDVNLILKEV--VTAANDSNLTEEKTISN----TAHTA------- 1681
EE T +P E + + KEV + + D + EEK+I+N TA
Sbjct: 947 EEDQSVTKEIPVEE----HSVFKEVDEIESVTDEIVEEEKSITNELVKEERTALEEIVEQ 1002
Query: 1680 ---DDVRKEMEVAIEERMQEKGVSYSE--KKAGTKSDTVGGRVDEMSGQGSQLSTKKLAI 1516
+ +E E+ EE ++E+G +Y + K+ G+ S+ + V+E +GS+ + I
Sbjct: 1003 RPDTEEVEETELVNEEVLKEEGSAYEKVVKEEGSASEKI---VEE---EGSEEESSSEEI 1056
Query: 1515 SSDVAVDPKMFEKHAS-TDHLQEQISDTNEAAVDDKINPEDMMKKVDTAINDAIFTEKKI 1339
+V+ ++ E+ S T+ + E+ T E D E+++++ + + + +
Sbjct: 1057 IEEVSSTEEVLEEEGSVTEEIVEEEVSTTEEVKDIGSVSEEVLEEEGFGTEEFVGQQGSV 1116
Query: 1338 ISNIIQISDDENK---STGITAEENMLEKGKLNSEIKTDRTSEILAGRSDEERDQVSQFS 1168
I I++ K G EE + E+G + EI + S + E+ D+V + +
Sbjct: 1117 IEEIVETESSTEKVLEDVGSNVEEIVQEEGPVAQEIVHEEVS------TTEKHDEVDRST 1170
Query: 1167 TEELLMCSGTVKDPNNFEKCSVSHRRQEQIGHKNDNAVIENLQAYAVNNCDTGAKDGNFT 988
TEE++ G+V + E+ S S E+ G + V E V ++ ++
Sbjct: 1171 TEEIVEKVGSVSEEIIVEEVSASEEIVEE-GSVTEEVVEEEKLINEVGETESVTEEIVQK 1229
Query: 987 EKENASKIVSSLHEDIKCTTEVRIAGELHEKRDLKSEF---KANTTLETVGGCVNEKSRH 817
E +A +++ E + E+ EK + E + + T E G +NE
Sbjct: 1230 EVSDAEEVLGQ---------EGSMNEEILEKESIVEEIVGPEGSVTEEIREGSINEDIVK 1280
Query: 816 VSQLSTEVLAMSSEMAEDAKVVG-TDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPP 640
+ ++ EV + + K+ TD + QL + + +E ++ +E A+
Sbjct: 1281 EASITEEVEQIEPVTGKVEKIESITDEIKEQL------VPEDIKEEQLDFEEIVAQRA-S 1333
Query: 639 TGDEKVGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVARFVNEESGYARQLPT 460
DEKV + E + ++E ++ E++ E+ + ++V G + ++
Sbjct: 1334 VNDEKV---EVASITEEVEEEEKSVSEEVLEE---EGSTTEKVV-------KGSSTEVVV 1380
Query: 459 EKLAMSTDTVGDYKISEKDIVSHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSE 280
E+ T+ + + + + + IV +E + ++D V D+ + + ++ + L
Sbjct: 1381 EEQGSVTENLLEEESASQGIVE--KEEFVDEEDSVKDQNVFEKEGSVTEQLVEEEKGLIN 1438
Query: 279 KEKENGNLKTECSVESTSAIAAGYARQLSTEELAMSTDIEE-DYKISEKDIVSHLLQEQV 103
++ E L TE S E S LSTEE+ + ++ EK + LL+E+
Sbjct: 1439 EDNEKEELITEMSEEIKSVNEEIEETDLSTEEIIKQQGLATYEFVEEEKSLTDKLLEEES 1498
Query: 102 HDKDEVVGETIHATDTVNKDETAATDDTLSEKE 4
K+ VGET +T V ++ + T++ + E++
Sbjct: 1499 VTKE--VGETELSTQEVVDEKVSVTEEVIEEEK 1529
Score = 116 bits (291), Expect = 6e-23
Identities = 226/1155 (19%), Positives = 485/1155 (41%), Gaps = 36/1155 (3%)
Frame = -3
Query: 3363 ENSMVTQGLEKESNVIVNVVIGDNKKCTAGSLLEKKDNVEVVIPSVKVRK---KRDPASC 3193
E VT + +E I N ++ + + ++E++ + E V + V + K + ++
Sbjct: 969 EIESVTDEIVEEEKSITNELVKEERTALE-EIVEQRPDTEEVEETELVNEEVLKEEGSAY 1027
Query: 3192 SKTISSCKPRKASINKTNENLNMPSTQINKQELAGVIVLSDNSDDAAVSKGKVKEANTVI 3013
K + K ++ K E +++ + V ++++ +G V E
Sbjct: 1028 EKVV---KEEGSASEKIVEEEGSEEESSSEEIIEEV----SSTEEVLEEEGSVTEEIVEE 1080
Query: 3012 KGATSSKKVKISSTGENSQERNSFANDAALNAKLQGSDKMKNTDVATENCVLKDKEKVSH 2833
+ +T+ + I S E E F + + + +++ T+ +TE VL+D S+
Sbjct: 1081 EVSTTEEVKDIGSVSEEVLEEEGFGTEEFVGQQGSVIEEIVETESSTEK-VLEDVG--SN 1137
Query: 2832 TSNISQEESSGANDVAVNEKLKASDIEKGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAK 2653
I QEE A ++ V+E++ ++ VD + + K G+VS ++ + +
Sbjct: 1138 VEEIVQEEGPVAQEI-VHEEVSTTEKHDEVDRSTTEEIVEKVGSVS--------EEIIVE 1188
Query: 2652 GISMNEKMKGKGSVAKNATAINAATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKR 2473
+S +E++ +GSV + EV E K+ +
Sbjct: 1189 EVSASEEIVEEGSVTE------------------------------EVVEEEKLINEVGE 1218
Query: 2472 SESKTCSSEKKNIGNTLQALDEENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKA 2293
+ES T +K + + + L +E E ++++ SI + G
Sbjct: 1219 TESVTEEIVQKEVSDAEEVLGQEGSMNEEILEKE-------------SIVEEIVGPEGSV 1265
Query: 2292 SCEKFNQSAKEFTMSTDVLKDAKVFEK----DVATHQLEKGSGSNDVVIDKNINAKVAVE 2125
+ + +E +++ D++K+A + E+ + T ++EK D + ++ + + E
Sbjct: 1266 T-----EEIREGSINEDIVKEASITEEVEQIEPVTGKVEKIESITDEIKEQLVPEDIKEE 1320
Query: 2124 KVDTEINVA----VFTEKGSISNTLHILEDINKKKEATNEEKLPEKGELSAELKPDS--- 1966
++D E VA V EK +++ I E++ +++++ +EE L E+G + ++ S
Sbjct: 1321 QLDFEEIVAQRASVNDEKVEVAS---ITEEVEEEEKSVSEEVLEEEGSTTEKVVKGSSTE 1377
Query: 1965 ---DSRSEFVATCVNEVSGQVNNLSIEEFTMSRDRPEDAEIF-KETVGTHQL-EEKVGST 1801
+ + + E S + EEF D +D +F KE T QL EE+ G
Sbjct: 1378 VVVEEQGSVTENLLEEESASQGIVEKEEFVDEEDSVKDQNVFEKEGSVTEQLVEEEKGLI 1437
Query: 1800 YAVPSGEKRDVNLILKEVVTAANDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGV 1621
EK ++ + E + + N+ I T + +++ K+ +A E ++E+
Sbjct: 1438 NE--DNEKEELITEMSEEIKSVNEE-------IEETDLSTEEIIKQQGLATYEFVEEEK- 1487
Query: 1620 SYSEKKAGTKSDTVGGRVDEMSGQ---GSQLSTKKLAISSDVAVDPKMFEKHASTDHLQE 1450
S ++K +S T E+S Q ++S + I + +V ++ E+ ++T+ + E
Sbjct: 1488 SLTDKLLEEESVTKEVGETELSTQEVVDEKVSVTEEVIEEEKSVSEEVLEEGSATEEVVE 1547
Query: 1449 QISDTNEAAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGITAEEN- 1273
+ S T E V++ E ++++ I EK + I+ +E +T I EE
Sbjct: 1548 EGSCT-EVVVEEGSCTEVVVEEGSCT---EIVVEKGSDTEIVV---EEGSATEIVVEEGS 1600
Query: 1272 ----MLEKGKLNSEIKTDRT--SEILAGRSDEERDQVSQ-FSTEELLMCSGTVKDPNNFE 1114
++E+G E+ + + E+L + V + S++ + G ++ N E
Sbjct: 1601 ATEVVVEEGSATEEVVEEGSVSEEMLEEEGSATEEVVEEGLSSDNVQKSKGVIE--NVGE 1658
Query: 1113 KCSVSHRRQEQIGHKNDNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKC 934
SV + E + K + + G D E N+ I++ H ++
Sbjct: 1659 IYSVKTAKDESMNEKIPLEKSSFVDDESFKG--QGPTDNVSVEDVNSEDIINE-HTPLEE 1715
Query: 933 T------TEVRIAGELHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEM 772
T TE ++H K + +E K N E + V EK++ + TE + + E
Sbjct: 1716 TKIEELPTEYITTADIHTKGE--TETKYNLIYEKINEEV-EKAKFQEEKITENIPVERES 1772
Query: 771 AEDAKVVGTDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEE 592
+ +V + ++++ DTN++ + N+ EK G L E
Sbjct: 1773 VTE-DIVQEPSLAQEVEQKESDTNEIEETKLANEKIIPEVSVTENVVEKEG-----LDTE 1826
Query: 591 NIVKKETAIDEKMQEKWQLKADAASEIVARFVNEESGYARQLPTEKLAMSTDTVGDYKIS 412
+++++ +I E++ E+ + A EIV EE ++ L EK ++ + VG
Sbjct: 1827 EVLEEDESITEEIVEE---EVSACEEIV-----EEEESSKIL--EKESIVEEIVGPEGSV 1876
Query: 411 EKDIVSHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVES 232
++IV H S + ++E+V E E + +++E+ KE ++ ++E
Sbjct: 1877 TEEIVDHGSFAEEVKEEELVTE-----------EAVQYEGSVTEEIKEEESITENEAIEE 1925
Query: 231 TSAIAAGYARQLSTEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDTV 52
++ + +T+E+ ++ + ++E + +++E+ +++VGE T+
Sbjct: 1926 SAFAEIIEEKGPNTDEIVKEEGLDTEEIVNEVSVTDEVIEEEKLVNEQIVGEERSVTEKP 1985
Query: 51 NKDETAATDDTLSEK 7
+ E +AT+D + E+
Sbjct: 1986 VEVERSATEDLVEEE 2000
Score = 107 bits (267), Expect = 4e-20
Identities = 242/1280 (18%), Positives = 497/1280 (38%), Gaps = 140/1280 (10%)
Frame = -3
Query: 3456 SVNQGVCNLSSSSTK-IENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNKKCT 3280
S+++ + S T+ I QE ST + + S +E+ +V V+ +
Sbjct: 2185 SISEKIVEKEESVTEEIVRQEE--STTEKIVKDVSPTEDFVEQTDSVTEKVIEQEGSNTE 2242
Query: 3279 AGSLLEKKDNV----EVVIPSVKVRKKRDPASCSKTISSCKPRKASINKTNENLNM---P 3121
+E+K++ E SV + + S +K I R I + N ++
Sbjct: 2243 VAEDVEEKESASDEHEQEDVSVNAQVTYEKKSVTKEIVDEVSRTEEIVEENGSVTEGVDE 2302
Query: 3120 STQINKQELAGVIVLSDNSDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSF 2941
+ + ++ + V + +D +V++ +V E +VI+ V T E QE S
Sbjct: 2303 TGSVTEEIIEEATVTEEVVEDGSVTE-EVVEDGSVIQEVVEDGSV----TEEIVQENGSV 2357
Query: 2940 ANDAALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQEESSGANDVAVNEKLKAS 2761
+ + +GS N +V E V + ++ + + +EE S ++ +
Sbjct: 2358 TEEIV---EEEGS---VNEEVEEEVSVSGEVDETEYVTEEVEEEGSVVEEIEGSVSEVVD 2411
Query: 2760 DIEKGVDTTVKDANHTKKGNVSIMVGP-----------IKQQKNVAKGISMNEKMKGKGS 2614
+ E D V+ A T++ + V +++ +++ + +S E+ + KG
Sbjct: 2412 ETELVNDEIVEQAPFTEEVEEQVSVNDEIIEDASVAEAVEESESITESVSQEEETE-KGF 2470
Query: 2613 VAKNATAINAATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSSEKKN- 2437
V + A T E G + + E+++V I K + E++ + E
Sbjct: 2471 VIEKVEETGAVTE-EIVQDGLITEEILEESESVNGEIINKESDAEEILETEFLTEEVVGQ 2529
Query: 2436 IGNTLQALDEENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEF 2257
G+T + + EE +V ++ K + + + + ++ G V + E+ A+E
Sbjct: 2530 AGSTSEEIVEEEGSVTKEVEEKESVTEELVDEGSVTEELVDEGSVTEEVVEQGGSIAQEI 2589
Query: 2256 ----TMSTDVLKDA----KVFEKD-VATHQL-EKGSGSNDVVIDKNINAKVAVEKVDTEI 2107
+ + ++++D +V EK+ AT ++ + GSG+ND V V E V+ EI
Sbjct: 2590 VEEESATEEIIRDETNVEEVLEKEGSATEEIVQDGSGTNDFV---GKQGSVIEEVVEEEI 2646
Query: 2106 NVAVFTEKGSISNTLHILEDINKKKEATNEEKLPEK--GELSAELKPDSDSRSEFVATCV 1933
+ K S +E+ + +++ E + E G+ + + D F V
Sbjct: 2647 STTEEKLKEEASAIEEFVEEESIREDVLEESLVTENVVGQQESVTEEIVDGEGSFTEDIV 2706
Query: 1932 NEVSGQVNNLSIEEFTMSRDRPEDAEIFKETVGTHQLEEKVGSTYAVPSGEKRDVNLILK 1753
E + ++E +++++ ED E+ E + +E++ T + E +++
Sbjct: 2707 EEEESVTEEIVVDEESVTKEIVEDEELVTEEI----VEDEGSFTEEIVEDEGSFTEEVIE 2762
Query: 1752 E--VVTAANDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYS-EKKAGTKSDT 1582
E ++ D+ EK + D + E +EE EK V+ E+K K +
Sbjct: 2763 ERSLIEEVEDTETVAEKEEGSVIKEIIDEKSLTEKIVEE---EKSVTEEVEEKESVKEEV 2819
Query: 1581 VGGR--VDEMSGQGSQLSTKKLA---ISSDVAVDPKMFEKHASTDHLQEQISDTNEAAVD 1417
R V+E + +LA I D+ V ++ E +TD EQ E +D
Sbjct: 2820 EEQRLVVEEEGSATEGIVEDRLATEGIVDDILVTEEIVEDGLATDEFVEQQGSIIEEVLD 2879
Query: 1416 DKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGITAEENMLEKGKLNSEIK 1237
D+ + + + + + + N+ I +I I + + E M+++G L +E+
Sbjct: 2880 DEGSVTEEIVEEEGSPNEEIVEGVSVIEEDDNIEPVSEEIVEGSVTEEMIKEG-LENEVI 2938
Query: 1236 TDR-------------------------TSEILAGRSDEERDQVSQFS-TEELLMCSGTV 1135
D T EI+ D + + S +EE++ V
Sbjct: 2939 LDEDSITEEALEKEGSVSEEIVEEMGSLTEEIVDEERSTSEDMIEEGSASEEIIQEESQV 2998
Query: 1134 KDPNNFEKCSVSHR--RQEQIGHKNDNAVIE-NLQAYAVNNCDTGAKDGNFTEKENASKI 964
++ E+ SV ++++ K IE N + + + G+ ++E +
Sbjct: 2999 EEV--VEEVSVIDEIVEEDELDTKEVVEEIEFNTEEVVEHKEEEGSVAEEIVQEEKEGSV 3056
Query: 963 VSSLHEDIKCTTEVRIA------GELHEKRDLKSEFKANTTLE--------------TVG 844
+ E++ TE + E+ E+R + E + N +E
Sbjct: 3057 NEEIIEEVGSITEEMVEQDVSDNEEIVEERSVIEEAEENVWIEKEVEEEGLDNEEVIDEE 3116
Query: 843 GCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVG---------------------TDVVTYQ 727
V+E++ ++ E+L SS++ ED KV ++ Y
Sbjct: 3117 DSVSEQAEEEVYINEEILKESSDV-EDVKVENELMNEEVNEETQSVAENNEEDKELDNYV 3175
Query: 726 LQEPSGDTNQVVVDEAVNKDEA---------AAKDCPPTGD-------------EKVGNI 613
++E T +VVVDE N E +D T D E+VG+
Sbjct: 3176 VEETESVTEEVVVDEVPNSKEVQEIESIIEEIVEDGLTTDDLVGQQGSVIEEVVEEVGSD 3235
Query: 612 AYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVA------RFVNEESGYARQLPTEKL 451
+ + EE + +E E + E ++ +I+ V EE + ++ TE+
Sbjct: 3236 SEEIVEEASITEEVEKKESVTEDILVEESVTGDILVEGSVTEEVVGEEKLVSEEIVTEEG 3295
Query: 450 AMSTDTVGD--YKISEKDIVSHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEK 277
+++ + V + E D + +++E + ++ V +E + +V +E + + E
Sbjct: 3296 SVAQEIVEEDAPATEEIDEIESVTEEVVEEEGPVDEEIVQEEGSVT-EEIIQGESKVEEV 3354
Query: 276 EKENGNLKTECSVESTSAIAAGYARQLSTEELAMSTDIEEDYKISEKDIVSHLLQEQVHD 97
+E G+ E VE SA + TEE+ ++ + + + +++EQ
Sbjct: 3355 VEEQGSENEEIFVEEVSASQEIVQNESGTEEILEKVSASQEI-VQDGSVTEQIIEEQKPV 3413
Query: 96 KDEVVGETIHATDTVNKDET 37
+EVV E T + ++E+
Sbjct: 3414 TEEVVNEEESITHEIIQEES 3433
Score = 103 bits (257), Expect = 5e-19
Identities = 260/1255 (20%), Positives = 506/1255 (40%), Gaps = 128/1255 (10%)
Frame = -3
Query: 3384 TVTAVRSENSMVTQGLEKESNVIVNVVIGDNKKCTAGSLLEKKDNVEVVIPSVKVRKKRD 3205
+VT E + TQ + E + VI + K + L E EVV +
Sbjct: 1498 SVTKEVGETELSTQEVVDEKVSVTEEVIEEEKSVSEEVLEEGSATEEVVEEGSCTEVVVE 1557
Query: 3204 PASCSKTI---SSCKPRKASINKTNENL--NMPSTQINKQELAG--VIVLSDNSDDAAVS 3046
SC++ + SC E + +T+I +E + V+V ++ + V
Sbjct: 1558 EGSCTEVVVEEGSCTEIVVEKGSDTEIVVEEGSATEIVVEEGSATEVVVEEGSATEEVVE 1617
Query: 3045 KGKVKEANTVIKGATSSKKVKISSTGENSQE-RNSFANDAALNAKLQGSDKMKNTDVATE 2869
+G V E +G+ + + V+ + +N Q+ + N + + D+ N + E
Sbjct: 1618 EGSVSEEMLEEEGSATEEVVEEGLSSDNVQKSKGVIENVGEIYSVKTAKDESMNEKIPLE 1677
Query: 2868 NCVLKDKEKVSH---TSNISQEESSGANDVAVNEKLKASDIEKGVDTTVKDANHTKKGNV 2698
D E T N+S E+ + + + + L+ + IE+ + A+ KG
Sbjct: 1678 KSSFVDDESFKGQGPTDNVSVEDVNSEDIINEHTPLEETKIEELPTEYITTADIHTKGET 1737
Query: 2697 SIMVGPIKQQKN--VAKGISMNEKMKGKGSVAKNATAINA------ATHLEKKNIG-NTL 2545
I ++ N V K EK+ V + + + A +E+K N +
Sbjct: 1738 ETKYNLIYEKINEEVEKAKFQEEKITENIPVERESVTEDIVQEPSLAQEVEQKESDTNEI 1797
Query: 2544 QALDVENKNV--EVTIEGKIQGKAKRSESKTCSSEKKNIGNTLQALDEENKNVEVTIDRK 2371
+ + N+ + EV++ + K + +++ E ++I T + ++EE E ++ +
Sbjct: 1798 EETKLANEKIIPEVSVTENVVEK-EGLDTEEVLEEDESI--TEEIVEEEVSACEEIVEEE 1854
Query: 2370 IQGKGKRSESKTGSIPVMVAGCVNKASCE--KFNQSAKEFTMSTDVLKDAKVFEKDVATH 2197
K ES I V G V + + F + KE + T+ +A +E V
Sbjct: 1855 ESSKILEKESIVEEI-VGPEGSVTEEIVDHGSFAEEVKEEELVTE---EAVQYEGSVTEE 1910
Query: 2196 QLEKGSGSNDVVIDKNINAKVAVEKVDT--EINVAVFTEKGSISNTLHILEDINKKKEAT 2023
E+ S + + I+++ A++ EK EI + I N + + +++ ++++
Sbjct: 1911 IKEEESITENEAIEESAFAEIIEEKGPNTDEIVKEEGLDTEEIVNEVSVTDEVIEEEKLV 1970
Query: 2022 NEE---------KLPEKGELSA--ELKPDSDSRSEFVATCVNEVSGQVNNLSIEEFTMSR 1876
NE+ + P + E SA +L + S +E V+ + Q+ + S+ E +
Sbjct: 1971 NEQIVGEERSVTEKPVEVERSATEDLVEEEASVTEKVSVHEGSTTEQILDESVAEEIVEE 2030
Query: 1875 DRPEDAEIFKETVGTHQLEEKVGSTY--------AVPS---------------------- 1786
+ D +I +E V ++ E+ GS +VP
Sbjct: 2031 EVSVDDKIIEEEVSVDEVVEEEGSVIEEIVEEEESVPEEILEEELSGSEEVLEDEWVTDA 2090
Query: 1785 --GEKRDVNLILKEVVTAANDSNLTEE---------KTISNTAHTADDVRKEMEVAIEER 1639
G++ V ++E+V + ++TEE K + ++V + IEE
Sbjct: 2091 FMGQEGSVIEEIEEIVDG--EGSITEEIVEDGSANEKIVEEEPSRVEEVLGKEGFVIEEI 2148
Query: 1638 MQEKGVSYSEKKAGTKSDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHAS-TD 1462
++E V E+ TK+ V E S + S + K + + ++ K+ EK S T+
Sbjct: 2149 IEEGSVI--EQVEDTKT------VSEKSEESSAIEEVK-EVKEEESISEKIVEKEESVTE 2199
Query: 1461 HLQEQISDTNEAAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGITA 1282
+ Q T E V D ED +++ D+ I E SN D E K + +
Sbjct: 2200 EIVRQEESTTEKIVKDVSPTEDFVEQTDSVTEKVIEQEG---SNTEVAEDVEEKESA--S 2254
Query: 1281 EENMLEKGKLNSEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKCSV 1102
+E+ E +N+++ ++ S + E D+VS+ TEE++ +G+V + + E SV
Sbjct: 2255 DEHEQEDVSVNAQVTYEKKSV-----TKEIVDEVSR--TEEIVEENGSVTEGVD-ETGSV 2306
Query: 1101 SHRRQEQIGHKNDNAVIENLQAYAVNN---CDTGAKDGNFTEK---ENAS---KIVS--- 958
+ E+ + ++ V + +DG+ TE+ EN S +IV
Sbjct: 2307 TEEIIEEATVTEEVVEDGSVTEEVVEDGSVIQEVVEDGSVTEEIVQENGSVTEEIVEEEG 2366
Query: 957 SLHEDIKCTTEVRIAGELHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSS 778
S++E+++ EV ++GE+ E + E +E G V E VS++ E ++
Sbjct: 2367 SVNEEVE--EEVSVSGEVDETEYVTEE------VEEEGSVVEEIEGSVSEVVDETELVND 2418
Query: 777 EMAEDAKVVGTDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYSLY 598
E+ E A T+ V Q+ V EAV + E+ + + + G + +
Sbjct: 2419 EIVEQAPF--TEEVEEQVSVNDEIIEDASVAEAVEESESITESVSQEEETEKGFVIEKVE 2476
Query: 597 EENIVKKETAIDEKMQEKWQLKADAAS-EIVARFVNEESGYARQLPTEKLAMSTDTVGDY 421
E V +E D + E+ ++++ + EI+ + + E + TE++ + +
Sbjct: 2477 ETGAVTEEIVQDGLITEEILEESESVNGEIINKESDAEEILETEFLTEEVVGQAGSTSEE 2536
Query: 420 KISEKDIVSHLSQEQIHDKDEVVDETIHATDTVNK-------------------DETAAT 298
+ E+ V+ +E+ +E+VDE + V++ +E +AT
Sbjct: 2537 IVEEEGSVTKEVEEKESVTEELVDEGSVTEELVDEGSVTEEVVEQGGSIAQEIVEEESAT 2596
Query: 297 -----DDTLSEKEKENGNLKTECSVESTSAIAAGYARQLSTEELAMSTDI---EEDYK-- 148
D+T E+ E TE V+ S +Q S E + +I EE K
Sbjct: 2597 EEIIRDETNVEEVLEKEGSATEEIVQDGSGTNDFVGKQGSVIEEVVEEEISTTEEKLKEE 2656
Query: 147 -------ISEKDIVSHLLQEQVHDKDEVVGETIHATDTVNKDETAATDDTLSEKE 4
+ E+ I +L+E + ++ VVG+ T+ + E + T+D + E+E
Sbjct: 2657 ASAIEEFVEEESIREDVLEESLVTEN-VVGQQESVTEEIVDGEGSFTEDIVEEEE 2710
Score = 101 bits (251), Expect = 3e-18
Identities = 238/1241 (19%), Positives = 486/1241 (39%), Gaps = 102/1241 (8%)
Frame = -3
Query: 3423 SSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNKKCTAGSLLEKKDNVE 3244
S+T++ +E GS V E S+ + LE+E + VV + ++ ++ + K +E
Sbjct: 1600 SATEVVVEE--GSATEEVVEEGSVSEEMLEEEGSATEEVV---EEGLSSDNVQKSKGVIE 1654
Query: 3243 VVIPSVKVRKKRDPASCSKTISSCKPRKASINKTNENLNMPSTQINKQELAGVIVLSDNS 3064
V V+ +D + K P + S +E+ N V V NS
Sbjct: 1655 NVGEIYSVKTAKDESMNEKI-----PLEKSSFVDDESFKGQGPTDN------VSVEDVNS 1703
Query: 3063 DDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSF---ANDAALNAKLQGSDKM 2893
+D ++E I + GE + N N+ AK Q
Sbjct: 1704 EDIINEHTPLEETKIEELPTEYITTADIHTKGETETKYNLIYEKINEEVEKAKFQEEKIT 1763
Query: 2892 KNTDVATENCVLKDKEKVSHTSNISQEESSGANDVA----VNEKL--KASDIEKGVDTTV 2731
+N V E+ ++ S + Q+ES N++ NEK+ + S E V+
Sbjct: 1764 ENIPVERESVTEDIVQEPSLAQEVEQKESD-TNEIEETKLANEKIIPEVSVTENVVEKEG 1822
Query: 2730 KDANHTKKGNVSIMVGPIKQQKNVAKGISMNE---KMKGKGSVAKNATAINAATHLEKKN 2560
D + + SI ++++ + + I E K+ K S+ + + E +
Sbjct: 1823 LDTEEVLEEDESITEEIVEEEVSACEEIVEEEESSKILEKESIVEEIVGPEGSVTEEIVD 1882
Query: 2559 IGNTLQALDVENKNVE--VTIEGKIQGKAKRSESKTCSSEKKNIGNTLQALDEENKNVEV 2386
G+ + + E E V EG + + K ES T E + I EE+ E+
Sbjct: 1883 HGSFAEEVKEEELVTEEAVQYEGSVTEEIKEEESIT---ENEAI--------EESAFAEI 1931
Query: 2385 TIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDVLKDAKVFEKDV 2206
I+ KG ++ + VN+ S ++ V ++ V EK V
Sbjct: 1932 -----IEEKGPNTDEIVKEEGLDTEEIVNEVSVTDEVIEEEKLVNEQIVGEERSVTEKPV 1986
Query: 2205 -----ATHQL--------EKGSGSNDVVIDKNINAKVAVEKVDTEINV--AVFTEKGSIS 2071
AT L EK S ++ ++ VA E V+ E++V + E+ S+
Sbjct: 1987 EVERSATEDLVEEEASVTEKVSVHEGSTTEQILDESVAEEIVEEEVSVDDKIIEEEVSVD 2046
Query: 2070 NTLH----ILEDINKKKEATNEEKLPEKGELSAELKPDSDSRSEFVATCVNEVSGQVNNL 1903
+ ++E+I +++E+ EE L E+ S E+ D F+ V ++ +
Sbjct: 2047 EVVEEEGSVIEEIVEEEESVPEEILEEELSGSEEVLEDEWVTDAFMGQ-EGSVIEEIEEI 2105
Query: 1902 SIEEFTMSRDRPEDAEIFKETVGTH--QLEEKVGSTYAVPSGEKRDVNLILKEVVTAAND 1729
E +++ + ED ++ V ++EE +G +++E++ +
Sbjct: 2106 VDGEGSITEEIVEDGSANEKIVEEEPSRVEEVLGKE-----------GFVIEEIIEEGSV 2154
Query: 1728 SNLTEE-KTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAGTKSDTVGGRVDEMSG 1552
E+ KT+S + + + + EV EE + EK V E V E
Sbjct: 2155 IEQVEDTKTVSEKSEESSAIEEVKEVKEEESISEKIVEKEES------------VTEEIV 2202
Query: 1551 QGSQLSTKKLAISSDVAVDPKMFEKHAS-TDHLQEQISDTNEAA--VDDKINPEDMMKKV 1381
+ + +T+K+ DV+ E+ S T+ + EQ E A V++K + D ++
Sbjct: 2203 RQEESTTEKIV--KDVSPTEDFVEQTDSVTEKVIEQEGSNTEVAEDVEEKESASDEHEQE 2260
Query: 1380 DTAINDAIFTEKKIISNIIQISDDENKSTGITAE---------------ENMLEKGKLNS 1246
D ++N + EKK ++ +I D+ +++ I E E ++E+ +
Sbjct: 2261 DVSVNAQVTYEKKSVTK--EIVDEVSRTEEIVEENGSVTEGVDETGSVTEEIIEEATVTE 2318
Query: 1245 EIKTDR--TSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKCSVSHRRQEQIGH 1072
E+ D T E++ S + TEE++ +G+V + E+ SV+ +E++
Sbjct: 2319 EVVEDGSVTEEVVEDGSVIQEVVEDGSVTEEIVQENGSVTEEIVEEEGSVNEEVEEEVSV 2378
Query: 1071 --------------KNDNAVIENLQAYAVNNCDTG-------AKDGNFTEK-ENASKIVS 958
+ + +V+E ++ D + FTE+ E +
Sbjct: 2379 SGEVDETEYVTEEVEEEGSVVEEIEGSVSEVVDETELVNDEIVEQAPFTEEVEEQVSVND 2438
Query: 957 SLHEDIKCTTEVRIAGELHEKRDLKSEFKANTTLETVG--GCVNEKSRHVSQLSTEVLAM 784
+ ED V + + E + E + +E V G V E+ ++ E+L
Sbjct: 2439 EIIEDASVAEAVEESESITESVSQEEETEKGFVIEKVEETGAVTEEIVQDGLITEEILEE 2498
Query: 783 SSEM--------AEDAKVVGTDVVTYQLQEPSGDTNQVVVDEA------VNKDEAAAKDC 646
S + ++ +++ T+ +T ++ +G T++ +V+E V + E+ ++
Sbjct: 2499 SESVNGEIINKESDAEEILETEFLTEEVVGQAGSTSEEIVEEEGSVTKEVEEKESVTEEL 2558
Query: 645 PPTGDEKVGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVARFVNEESGYARQ- 469
G + E +V++ +I +++ E+ A EI+ N E ++
Sbjct: 2559 VDEGSVTEELVDEGSVTEEVVEQGGSIAQEIVEE----ESATEEIIRDETNVEEVLEKEG 2614
Query: 468 LPTEKLAMSTDTVGDYKISEKDIVSHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDT 289
TE++ D+ + ++ +EVV+E I T+ K+E +A ++
Sbjct: 2615 SATEEIVQDGSGTNDFVGKQGSVI-----------EEVVEEEISTTEEKLKEEASAIEEF 2663
Query: 288 LSEKEKENGNLKTECSVESTSAIAAGYARQLSTEELAMSTDIEEDYK-------ISEKDI 130
+ E+ L+ E+ ++ E + + DI E+ + + E+ +
Sbjct: 2664 VEEESIREDVLEESLVTENVVGQQESVTEEIVDGEGSFTEDIVEEEESVTEEIVVDEESV 2723
Query: 129 VSHLLQEQVHDKDEVVGETIHATDTVNKDETAATDDTLSEK 7
+++++ +E+V + T+ + +DE + T++ + E+
Sbjct: 2724 TKEIVEDEELVTEEIVEDEGSFTEEIVEDEGSFTEEVIEER 2764
Score = 89.4 bits (220), Expect = 1e-14
Identities = 190/909 (20%), Positives = 383/909 (42%), Gaps = 51/909 (5%)
Frame = -3
Query: 2574 LEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSSEKKNIGNTLQALDEENKN 2395
+E+ N ++ + ENK E T EG + + E + E + I + ++ +E+ +N
Sbjct: 605 MEETEKENEIEKIMDENKETEQTEEGNTEEFVQEKELNQETLENEIIVDHIKE-EEDTRN 663
Query: 2394 VEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDVLKDAKVFE 2215
V+ + + ES +PV + + K N+ +EF ++ L++
Sbjct: 664 VK-------EQESVLEESPIEELPV-------ENNIGKINEEVEEFILNEIPLEEQ--VP 707
Query: 2214 KDVATHQLEKGSGSNDVVIDKNI-NAKVAVEKVDTEINVAVFTEKGSISNTLHILEDINK 2038
K++ ++E+ VV D+ I +A+E D ++ TE+ ++ ++ + +
Sbjct: 708 KELPQEEIEE-----IVVEDEEIPEGGIAIE--DVPVDEETVTEEITVDEKIY--DKLPN 758
Query: 2037 KKEATNEEKLPEKGELSAELKPDSDSRSEFVAT----CVNEVSGQVNNLSIEEFTMSRDR 1870
+ E NEE E L+ ++ + + E + E + + + +EE ++ D
Sbjct: 759 EIETVNEEMPVEDETLTEQISSEHERVPEEIIEEKPFTEGEETESLTDEIVEEGVVTDDI 818
Query: 1869 PEDAEIFKETVGTHQLEEKVGSTYAVPSGEKRDVNLILKEVVTAANDSNLTEEKTISNTA 1690
PE+ I EKV +GE + ++I ++V D ++TEE +
Sbjct: 819 PEEQII----------TEKVQEEEEFVTGELSEEDIINEKV--QEEDESVTEELPEEDII 866
Query: 1689 HTADDVRKEMEVAIEERMQE----KGVSYSEKKAGTKSDTVGGRVDEMSGQGSQLS---- 1534
+ + V++E E A +E +Q+ K V Y E D ++E +G ++
Sbjct: 867 N--EKVQEEEESAYQEIVQDGSVTKDVEYKELVNDDVRDKENFVIEEDPFKGQLINEGLP 924
Query: 1533 ------TKKLAISS----------DVAVDPKM-FEKHASTDHLQEQISDTNEAAVDDKIN 1405
TK+L + D +V ++ E+H+ + E S T+E ++K
Sbjct: 925 VEEEFVTKELPVKEESVFEELTEEDQSVTKEIPVEEHSVFKEVDEIESVTDEIVEEEKSI 984
Query: 1404 PEDMMKKVDTAINDAIFT--EKKIISNIIQISDDENKSTGITAEENMLEKGKLNSEIKTD 1231
+++K+ TA+ + + + + + ++++ K G E+ + E+G + +I +
Sbjct: 985 TNELVKEERTALEEIVEQRPDTEEVEETELVNEEVLKEEGSAYEKVVKEEGSASEKIVEE 1044
Query: 1230 RTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKCSVSHRRQEQIGHKNDNAVI 1051
SE + S+E ++VS STEE+L G+V + E+ S + ++ IG ++ +
Sbjct: 1045 EGSEEESS-SEEIIEEVS--STEEVLEEEGSVTEEIVEEEVSTTEEVKD-IGSVSEEVLE 1100
Query: 1050 ENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCTTEVRIAGE-------LHEK- 895
E G+ E E++++ V ED+ E + E +HE+
Sbjct: 1101 EEGFGTEEFVGQQGSVIEEIVETESSTEKVL---EDVGSNVEEIVQEEGPVAQEIVHEEV 1157
Query: 894 --RDLKSEFKANTTLETVGGCVNEKSRHVSQ-LSTEVLAMSSEMAEDAKVVGTDVVTYQL 724
+ E +TT E V EK VS+ + E ++ S E+ E+ V V +L
Sbjct: 1158 STTEKHDEVDRSTTEEIV-----EKVGSVSEEIIVEEVSASEEIVEEGSVTEEVVEEEKL 1212
Query: 723 QEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEENIVKKETAIDEKMQEK 544
G+T V +E V K+ + A++ G E N E I++KE+ ++E + +
Sbjct: 1213 INEVGETESVT-EEIVQKEVSDAEEV--LGQEGSMN-------EEILEKESIVEEIVGPE 1262
Query: 543 WQLKADAASEIVARFVNEESGYARQLP--------TEKLAMSTDTVGDYKISEKDIVSHL 388
+ + + + +E+ ++ EK+ TD +I E+ + +
Sbjct: 1263 GSVTEEIREGSINEDIVKEASITEEVEQIEPVTGKVEKIESITD-----EIKEQLVPEDI 1317
Query: 387 SQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVESTSAIAAGY 208
+EQ+ D +E+V + D K E A+ + + E+EK E +T + G
Sbjct: 1318 KEEQL-DFEEIVAQRASVND--EKVEVASITEEVEEEEKSVSEEVLEEEGSTTEKVVKGS 1374
Query: 207 ARQLSTEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDTVNKDETAAT 28
STE + +EE ++E + + + +K+E V E D ++ +
Sbjct: 1375 ----STEVV-----VEEQGSVTENLLEEESASQGIVEKEEFVDEEDSVKDQNVFEKEGSV 1425
Query: 27 DDTLSEKEK 1
+ L E+EK
Sbjct: 1426 TEQLVEEEK 1434
Score = 65.9 bits (159), Expect = 1e-07
Identities = 160/791 (20%), Positives = 316/791 (39%), Gaps = 20/791 (2%)
Frame = -3
Query: 3468 EKTGSVNQGVCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNK 3289
EK GSVN+ + S T+ E E S + E S++ E E NV + + +
Sbjct: 3051 EKEGSVNEEIIEEVGSITE-EMVEQDVSDNEEIVEERSVIE---EAEENVWIEKEVEE-- 3104
Query: 3288 KCTAGSLLEKKDNVEVVIPSVKVRKK-RDPASCSKTISSCKPRKASINKTNENLNMPSTQ 3112
E DN EV+ V ++ + ++ I + NE +N +
Sbjct: 3105 --------EGLDNEEVIDEEDSVSEQAEEEVYINEEILKESSDVEDVKVENELMN---EE 3153
Query: 3111 INKQELAGVIVLSDNSDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSFAND 2932
+N++ + V +N +D + V+E +V + + E D
Sbjct: 3154 VNEETQS---VAENNEEDKELDNYVVEETESVTEEVVVDEVPNSKEVQEIESIIEEIVED 3210
Query: 2931 AALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQE---ESSGANDVAVNEKLKAS 2761
L G +V E V D E++ ++I++E + S D+ V E +
Sbjct: 3211 GLTTDDLVGQQGSVIEEVVEE--VGSDSEEIVEEASITEEVEKKESVTEDILVEESVTGD 3268
Query: 2760 DIEKGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATAINAA 2581
+ +G S+ + ++K V++ I E GSVA+ +A
Sbjct: 3269 ILVEG----------------SVTEEVVGEEKLVSEEIVTEE-----GSVAQEIVEEDAP 3307
Query: 2580 THLEKKNIGNTLQALDVENKNVEVTI---EGKIQGKAKRSESKTCSSEKKNIGNTLQALD 2410
E I + + + E V+ I EG + + + ESK ++ G+ + +
Sbjct: 3308 ATEEIDEIESVTEEVVEEEGPVDEEIVQEEGSVTEEIIQGESKVEEVVEEQ-GSENEEIF 3366
Query: 2409 EENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDVLKD 2230
E + I + G + E + S ++ G V + E+ +E
Sbjct: 3367 VEEVSASQEIVQNESGTEEILEKVSASQEIVQDGSVTEQIIEEQKPVTEEV--------- 3417
Query: 2229 AKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTEINVA--VFTEKGSISNTL-- 2062
V E++ TH++ + + V+ + VA E V+ ++V + ++GS++ +
Sbjct: 3418 --VNEEESITHEIIQEESHVEKVVQQG---SVAEEVVENPVSVTEEIVEKEGSVTEDIGQ 3472
Query: 2061 --HILEDINKKKEATNEEKLPEKGELSAELKPDSDSRSEFVATCVNEVSGQVNNLSI--E 1894
++ E+I +++E NEE L E+ ++ D+ FV Q+++ I E
Sbjct: 3473 EGYVAEEIVEEEEFDNEEILEEESVAEEFVEEGFDNEEIFVE--------QISDSEIVKE 3524
Query: 1893 EFTMSRDRPEDAEIFKETVGTHQLEEKVGSTYAVPSGEKRDVNLILKEVVTAANDSNLTE 1714
E +++ + E+ + E + LEE+ T + E IL+E + N+ L E
Sbjct: 3525 ENSVNEEVLEEEGSYTEEI----LEEEGSYTEEILEEEGSFTEEILEEE-GSYNEEILEE 3579
Query: 1713 EKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAGTKSDTV-----GGRVDEMSGQ 1549
E + + +++ +E EE ++E+G S ++ G SD G D GQ
Sbjct: 3580 EGSYN------EEILEEEGSYNEEILEEEG-SATDYFVGQGSDNEEIIEEGSATDYFVGQ 3632
Query: 1548 GSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDTNEAAVDDKINPEDMMKKVDTAI 1369
GS + + SD + ++ E+ ++TD+ Q S E ++ ++ E + + +A
Sbjct: 3633 GSA-TDYFVGQGSD---NEEIIEEGSATDYFVGQGSIIEEVLEEEGLDTEKVFENEGSAT 3688
Query: 1368 NDAIFTEKKIISNIIQISDDENKSTGITAEENMLEKGKLNSEIKTDRTSEILAGRSDEER 1189
F E + + +++ ++ N EN+LE+ +N K + +E + + E
Sbjct: 3689 E---FEETESFTEVVEETESVN--------ENILEETSINEVQKIESITEDIKEQLVPEE 3737
Query: 1188 DQVSQFSTEEL 1156
+ Q +EE+
Sbjct: 3738 IKEEQLDSEEI 3748
>ref|WP_003093445.1| flagellar biosynthesis protein FliS [Streptococcus vestibularis]
gi|311100697|gb|EFQ58902.1| putative flagellar protein
FliS [Streptococcus vestibularis F0396]
Length = 2281
Score = 118 bits (295), Expect = 2e-23
Identities = 189/1127 (16%), Positives = 452/1127 (40%), Gaps = 47/1127 (4%)
Frame = -3
Query: 3492 SRSRASYREKTGSVNQGVCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVIV 3313
S S + + S + V +S S + N E+A + + V + S+ + S I
Sbjct: 1151 STSASESASTSASESASVSASNSESQSLSNSESASESAS-VSTSQSVSNSDYDSLSASIS 1209
Query: 3312 NVVIGDNKKCTAGSLLEKKDNVEVVIPSVKVRKKRDPASCSKTISSCKPRKASINKTNEN 3133
N + + S E + V S + + AS S++IS + S + + +
Sbjct: 1210 ESQSVSNSESASVSASESASESDSVSESQSLSNS-ESASTSESISESQSVSNSESASESD 1268
Query: 3132 LNMPSTQINKQELAGVIVLSDNSDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQE 2953
S ++ + A L S+ +VS + + + + S + +S E+ E
Sbjct: 1269 SVSESQSVSNSDSASESALI--SESQSVSNSESASTSASVSTSQSLSNSESASVSESVSE 1326
Query: 2952 RNSFANDAALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQEESSGANDVAVNEK 2773
S +N + + S ++ A+ + + + + VS++ + S+ +S + N +
Sbjct: 1327 SQSVSNSESASISASESVSTSASESASTSASISESQSVSNSESASESDSVSTSQSVSNSE 1386
Query: 2772 LKASDIEKGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATA 2593
++ +T + ++++ +VS + + N ++ S +E + S++ + +A
Sbjct: 1387 SASTSASV---STSQSVSNSESASVSESISDSQSVSN-SESSSESESISESQSLSNSESA 1442
Query: 2592 INAATHLEKKNIGNTLQALDVEN-------KNVEVTIEGKIQGKAKRSESKTCSSEKKNI 2434
+ + LE +++ N+ A + N E + E + +++ + SSE +I
Sbjct: 1443 SVSVSILESQSVSNSESASTSVSISESQSVSNSESSSESESVSESQSVSNSESSSESASI 1502
Query: 2433 GNTLQALDEENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFT 2254
+ + E+ + +I S S + SI + +++S E + S +
Sbjct: 1503 SESQSVSNSESASTSESISESQSLSNSESASTSASISESQSVSNSESSSESASISESQSV 1562
Query: 2253 MSTDVLKDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAV---------EKVDTEINV 2101
+++ ++ + + E S S V ++++ + + V +
Sbjct: 1563 SNSESASESASISESQSLSNSESASESASVSTSQSVSNSESASVSESVSESQSVSNSESA 1622
Query: 2100 AVF-TEKGSISNTLHILEDINKKKEATNEEKLPEKGELS-AELKPDSDSRSEFVATCVNE 1927
+V +E S S+++ + ++ + A+ E + E +S +E +SDS SE + +E
Sbjct: 1623 SVSASESASESDSVSESQSLSNSESASTSESISESQSVSNSESASESDSVSESQSLSNSE 1682
Query: 1926 VSGQVNNLSIEEFTMSRDRPEDAEIFKETVGTHQLE-----EKVGSTYAVPSGEKRDVNL 1762
+ ++S + + D +E E+ E E V + ++ + E V++
Sbjct: 1683 SASVSASISESQSVSNSDSASVSESISESQSLSNSESASESESVSESQSLSNSESASVSV 1742
Query: 1761 ILKEVVTAAND------SNLTEEKTISNT--AHTADDVRKEMEVAIEERMQEKG-VSYSE 1609
+ E + +N ++++E +++SN+ A ++ + + V+ E E +S S+
Sbjct: 1743 SISESQSVSNSESASLSASISESQSVSNSESASESESISESQSVSNSESASESASISESQ 1802
Query: 1608 KKAGTKSDTVGGRVDE-MSGQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDTN 1432
+ + S ++ + E S S+ +++ ++S ++ +++ + +SD+
Sbjct: 1803 SVSNSVSASLSASISESQSVSNSESASESESVSESQSLSNSESASESASISESQSVSDSE 1862
Query: 1431 EAAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGITAEENMLEKGKL 1252
A+V + I+ ++ ++A +E + +SN S+ + S I+ +++
Sbjct: 1863 SASVSESISESQLVSNSESASESDSVSESQSLSN----SESASTSESISESQSVSNSESA 1918
Query: 1251 NSEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKCSVSHRRQEQIGH 1072
+ + + S E D VS+ + +N E SVS E
Sbjct: 1919 SESDSVSESQSVSNSDSASESDSVSE------------SQSLSNSESASVSVSISESQSL 1966
Query: 1071 KNDNAVIEN---LQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCTTEVRIAGELH 901
N + E+ ++ +V+N D ++ + +E ++ S VS+ + +E +
Sbjct: 1967 SNSESASESESISKSQSVSNSDLASESDSVSESQSVSNSVSA--SESASISESQSVSNSE 2024
Query: 900 EKRDLKSEFKANTTLETVGGCV---NEKSRHVSQLSTEVLAMSSEMAEDAKVVGTD--VV 736
+S FK+ + + V N +S+ VS ++E + S+ ++E V ++
Sbjct: 2025 SASTSESIFKSQSVSNSESASVSVSNSESQSVS--NSESASTSASISESQSVSNSESAST 2082
Query: 735 TYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEENIVKKETAIDEK 556
+ + E +N + E+ + E+ + + + + S+ E V +
Sbjct: 2083 SESISESQSVSNSMSASESESISESQL-----VSNSESASTSVSISESQSVSNSESASIS 2137
Query: 555 MQEKWQLKAD-----AASEIVARFVNEESGYARQLPTEKLAMSTDTVG-DYKISEKDIVS 394
E A +ASE + +E + + + +L ++++ ISE VS
Sbjct: 2138 ASESASTSASESASTSASESASTSASESASVSESISESQLVSNSESASLSASISESQSVS 2197
Query: 393 HLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLK 253
+ + E+I + +V+ E+A+T + S E ++ K
Sbjct: 2198 -------NSESSPESESISESQSVSNSESASTSASESSSEVKDPKQK 2237
>gb|EWC75624.1| hypothetical protein C923_03695 [Plasmodium falciparum UGT5.1]
Length = 4217
Score = 117 bits (293), Expect = 4e-23
Identities = 243/1200 (20%), Positives = 479/1200 (39%), Gaps = 55/1200 (4%)
Frame = -3
Query: 3468 EKTGSVNQGVCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNK 3289
EK GSVN+ + S T+ E E S + E S++ E E NV + + +
Sbjct: 2020 EKEGSVNEEIIEEVGSITE-EMVEQDVSDNEEIVEERSVIE---EAEENVWIEKEVEE-- 2073
Query: 3288 KCTAGSLLEKKDNVEVVIPSVKVRKK-RDPASCSKTISSCKPRKASINKTNENLNMPSTQ 3112
E DN EV+ V ++ + ++ I + NE +N +
Sbjct: 2074 --------EGLDNEEVIDEEDSVSEQAEEEVYINEEILKESSDVEDVKVENELMN---EE 2122
Query: 3111 INKQELAGVIVLSDNSDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSFAND 2932
+N++ + V +N +D + V+E +V + + E D
Sbjct: 2123 VNEETQS---VAENNEEDKELDNYVVEETESVTEEVVVDEVPNSKEVQEIESIIEEIVED 2179
Query: 2931 AALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQE---ESSGANDVAVNEKLKAS 2761
L G +V E V D E++ ++I++E + S D+ V E +
Sbjct: 2180 GLTTDDLVGQQGSVIEEVVEE--VGSDSEEIVEEASITEEVEKKESVTEDILVEESVTGD 2237
Query: 2760 DIEKGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATAINAA 2581
+ +G S+ + ++K V++ I E GSVA+ +A
Sbjct: 2238 ILVEG----------------SVTEEVVGEEKLVSEEIVTEE-----GSVAQEIVEEDAP 2276
Query: 2580 THLEKKNIGNTLQALDVENKNVEVTI---EGKIQGKAKRSESKTCSSEKKNIGNTLQALD 2410
E I + + + E V+ I EG + + + ESK ++ G+ + +
Sbjct: 2277 ATEEIDEIESVTEEVVEEEGPVDEEIVQEEGSVTEEIIQGESKVEEVVEEQ-GSENEEIF 2335
Query: 2409 EENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDVLKD 2230
E + I + G + E + S ++ G V + E+ +E + +
Sbjct: 2336 VEEVSASQEIVQNESGTEEILEKVSASQEIVQDGSVTEQIIEEQKPVTEEVVNEEESITH 2395
Query: 2229 AKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTEINVAVFTEKGSISNTLHILE 2050
+ E+ +++GS + +VV + V E V+ E +V + I E
Sbjct: 2396 EIIQEESHVEKVVQQGSVAEEVVENP---VSVTEEIVEKEGSVTEDIGQEEIKEEQLDSE 2452
Query: 2049 DINKKKEATNEEKLPEKGELSAELKPDSDSRSEFVATCVNEVSGQVNNLSIEEFTMSRDR 1870
+I ++K + NEE + E+G ++ E+K +S +E V V E SI+E
Sbjct: 2453 EIKEQKGSVNEEVVEEEGSVTEEIKEQEESVNEEVLEEVEETE------SIKE------- 2499
Query: 1869 PEDAEIFKETVGTHQLEEKVGSTYAVPSGEKRDVNLILKEVVTAANDSNLTEEKTISNTA 1690
EI + + T ++ E+ T KEVV + + EK + +
Sbjct: 2500 ----EIVEGGIATQEIIEEESDT---------------KEVV---EEEVIDSEKLVDAGS 2537
Query: 1689 HTADDVRKEMEV---AIEERMQEKGVSYSEKKAGTKSDTVGGRVDEMSG-QGSQLSTKKL 1522
T + + +E+ V +EE + V +K + G +D+ G QGS +T+++
Sbjct: 2538 VTGEVMPEEVSVTDEVVEEGSTTEEVLEEQKSVNEEVVEDGLTIDDFVGLQGS--TTEEV 2595
Query: 1521 AISSDVAVDPKMFEKHASTDHLQEQISDTNEAAVDDKINPEDMMKKVDTAINDAIFTEKK 1342
A++ + E+ A+ + +++Q+S T ED+++K + ++N+ I E
Sbjct: 2596 VEEDGSAIEKILEEETATEEIVEKQVSVT-----------EDIVEK-EGSVNEEIIEEAS 2643
Query: 1341 IISNIIQISDDENKSTG---ITAEENMLEKGKLNSEIKTDRTSEILAGRSDEER-----D 1186
+ IIQ + G EE + E+G +++EI+ + + +E D
Sbjct: 2644 VAEEIIQGGSFTEEIVGQEESATEEVIDEEGLISNEIEEEEEKSVTEEMIEEVEEVSVDD 2703
Query: 1185 QVSQFS----TEELLMCSGTVKDPNNFEKCSVSHRRQEQIGHKNDNAVIENLQAYAVNNC 1018
+V + S EE+ + S T + C E+I + +A E + +V +
Sbjct: 2704 EVEEVSVDDEVEEVSVKSVTDEIVQEESVC-------EEILEQEVSASEEYVDDKSVTDD 2756
Query: 1017 DTGAKDGNFTEKENASKIVSSLHEDIKCTTE--VRIAGELHEKRDLKSEFKANTTLETVG 844
G + + EN + + E K E V G + E++ ++ A +E +
Sbjct: 2757 FVGHERSVIQDVENTESVTEEIAEVDKSVIEEAVEKQGSVTEEK-VQEGVSAIEEIEEIE 2815
Query: 843 GCVN--EKSRHVSQLSTEVLAMSSEMAEDAKVVGTDVVTYQ-------LQEPSGDTNQVV 691
E+ V++ E+ +++ E+AE+ K V + V Q ++E DT +V+
Sbjct: 2816 SVTEEIEEIESVTEEIEEIESVTEEIAEEDKSVIEEAVEKQGSVTEEIVEEEELDTEEVL 2875
Query: 690 VDEAV----------NKDEAAAKDCPPTGDEKVGNI----AYSLYEENIVKKETAIDEKM 553
D++V KDE+ AK+ +++ ++ + Y +++E+A ++
Sbjct: 2876 EDKSVTGDVVEQEGSGKDESEAKESFTEEVDELKSVKEEDQETEYISREIEEESATEQHS 2935
Query: 552 QEKWQLKADAA-SEIVARFVNEESGYARQLPTEKLAMSTDTVGDYKISEKDIVSHLSQEQ 376
+++ + + +E + + + EE T+++ T +V + + E+ + +E+
Sbjct: 2936 EQELSINKEVVETESLTKDIEEEKS-----TTQEILEETQSVNEEIVEEERDTDEVLKEK 2990
Query: 375 IHDKDEVVDETIHATDTV-----NKDETAATDDTLSEKEKENGNLKTECSVESTSAIAAG 211
+ +EV++E T+ + DE +D +E+ KE TE VE S
Sbjct: 2991 VSPSEEVIEEQASTTEEFVEERSSTDEIVEVEDLFTEEVKEREGSVTEEIVEEGSDTGEI 3050
Query: 210 YARQLS-TEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDTVNKDETA 34
+ S TEE+ E+ E I +LQ V +E VG+ + + + E+A
Sbjct: 3051 VEEEGSDTEEILEEGSFNEEIVEEEGSITEEILQGSV--TEEFVGQQGSVIEEIVETESA 3108
Score = 110 bits (276), Expect = 3e-21
Identities = 243/1292 (18%), Positives = 521/1292 (40%), Gaps = 152/1292 (11%)
Frame = -3
Query: 3456 SVNQGVCNLSSSSTK-IENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNKKCT 3280
S+++ + S T+ I QE ST + + S +E+ +V V+ +
Sbjct: 1161 SISEKIVEKEESVTEEIVRQEE--STTEKIVKDVSPTEDFVEQTDSVTEKVIEQEGSNTE 1218
Query: 3279 AGSLLEKKDNV----EVVIPSVKVRKKRDPASCSKTISSCKPRKASINKTNENLNM---P 3121
+E+K++ E SV + + S +K I R I + N ++
Sbjct: 1219 VAEDVEEKESASDEHEQEDVSVNAQVTYEKKSVTKEIVDEVSRTEEIVEENGSVTEGVDE 1278
Query: 3120 STQINKQELAGVIVLSDNSDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSF 2941
+ + ++ + V + +D +V++ +V E +VI+ V EN
Sbjct: 1279 TGSVTEEIIEEATVTEEVVEDGSVTE-EVVEDGSVIQEVVEDGSVTEEIVQENGSVTEEI 1337
Query: 2940 AND-AALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQ--EESSGANDVAVNEKL 2770
+ ++N +++ + TE + +E+ S ++S+ +E+ ND V +
Sbjct: 1338 VEEEGSVNEEVEEEVSVSGEVDETEYVTEEVEEEGSEEGSVSEVVDETELVNDEIVEQAP 1397
Query: 2769 KASDIEKGV---DTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNA 2599
++E+ V D ++DA+ + +++ +++ + +S E+ + KG V +
Sbjct: 1398 FTEEVEEQVSVNDEIIEDAS---------VAEAVEESESITESVSQEEETE-KGFVIEKV 1447
Query: 2598 TAINAATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSSEKKN-IGNTL 2422
A T E G + + E+++V I K + E++ + E G+T
Sbjct: 1448 EETGAVTE-EIVQDGLITEEILEESESVNGEIINKESDAEEILETEFLTEEVVGQAGSTS 1506
Query: 2421 QALDEENKNVEVTIDRK------IQGKGKRSESKT--GSIP--VMVAGCVNKASCEKFNQ 2272
+ + EE +V ++ K + +G +E GS+ ++ G V + E+
Sbjct: 1507 EEIVEEEGSVTKEVEEKESVTEELVDEGSVTEELVDEGSVTEELVDEGSVTEEVVEQGGS 1566
Query: 2271 SAKEF----TMSTDVLKDA----KVFEKD-VATHQL-EKGSGSNDVV------IDKNINA 2140
A+E + + ++++D +V EK+ AT ++ + GSG+ND V I++ +
Sbjct: 1567 IAQEIVEEESATEEIIRDETNVEEVLEKEGSATEEIVQDGSGTNDFVGKQGSVIEEVVEE 1626
Query: 2139 KVAV--EKVDTEIN-VAVFTEKGSISNTLH----ILEDINKKKEATNEEKLPEKGELSAE 1981
+++ EK+ E + + F E+ SI + + E++ ++E+ EE + +G + +
Sbjct: 1627 EISTTEEKLKEEASAIEEFVEEESIREDVLEESLVTENVVGQQESVTEEIVDGEGSFTED 1686
Query: 1980 LKPDSDSRSEFVATCVNEVSGQVNNLSIEEFTMSRDRPEDAEIFKETVGTHQLEEKVGST 1801
+ + +S +E + V+ ++ +E+ + + ++ +E + L E+V T
Sbjct: 1687 IVEEEESVTEEIVVDEESVTKEI----VEDEELVTEEIDEGSFTEEVIEERSLIEEVEDT 1742
Query: 1800 YAVPSGEKRDVNLILKEVVT--AANDSNLTEEKTISNTAHTADDVRKEMEVAIEERM--Q 1633
V E+ V +KE++ + + + EEK+++ + V++E+E E+R+ +
Sbjct: 1743 ETVAEKEEGSV---IKEIIDEKSLTEKIVEEEKSVTEEVEEKESVKEEVE---EQRLVVE 1796
Query: 1632 EKGVSYSEKKAGTKSDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQ 1453
E+G S T G D ++ +G I D+ V ++ E +TD
Sbjct: 1797 EEG-----------SATEGIVEDRLATEG---------IVDDILVTEEIVEDGLATDEFV 1836
Query: 1452 EQISDTNEAAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGITAEEN 1273
EQ E +DD+ + + + + + + N+ I +I I + + E
Sbjct: 1837 EQQGSIIEEVLDDEGSVTEEIVEEEGSPNEEIVEGVSVIEEDDNIEPVSEEIVEGSVTEE 1896
Query: 1272 MLEKGKLNSEIKTDR-------------------------TSEILAGRSDEERDQVSQFS 1168
M+++G L +E+ D T EI+ D + + S
Sbjct: 1897 MIKEG-LENEVILDEDSITEEALEKEGSVSEEIVEEMGSLTEEIVDEERSTSEDMIEEGS 1955
Query: 1167 -TEELLMCSGTVKDPNNFEKCSVSHR--RQEQIGHKNDNAVIE-NLQAYAVNNCDTGAKD 1000
+EE++ V++ E+ SV ++++ K IE N + + + G+
Sbjct: 1956 ASEEIIQEESQVEEV--VEEVSVIDEIVEEDELDTKEVVEEIEFNTEEVVEHKEEEGSVA 2013
Query: 999 GNFTEKENASKIVSSLHEDIKCTTEVRIA------GELHEKRDLKSEFKANTTLE----- 853
++E + + E++ TE + E+ E+R + E + N +E
Sbjct: 2014 EEIVQEEKEGSVNEEIIEEVGSITEEMVEQDVSDNEEIVEERSVIEEAEENVWIEKEVEE 2073
Query: 852 ---------TVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVG---------------- 748
V+E++ ++ E+L SS++ ED KV
Sbjct: 2074 EGLDNEEVIDEEDSVSEQAEEEVYINEEILKESSDV-EDVKVENELMNEEVNEETQSVAE 2132
Query: 747 -----TDVVTYQLQEPSGDTNQVVVDEAVNKDEA---------AAKDCPPTGD------- 631
++ Y ++E T +VVVDE N E +D T D
Sbjct: 2133 NNEEDKELDNYVVEETESVTEEVVVDEVPNSKEVQEIESIIEEIVEDGLTTDDLVGQQGS 2192
Query: 630 ------EKVGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVA------RFVNEE 487
E+VG+ + + EE + +E E + E ++ +I+ V EE
Sbjct: 2193 VIEEVVEEVGSDSEEIVEEASITEEVEKKESVTEDILVEESVTGDILVEGSVTEEVVGEE 2252
Query: 486 SGYARQLPTEKLAMSTDTVGD--YKISEKDIVSHLSQEQIHDKDEVVDETIHATDTVNKD 313
+ ++ TE+ +++ + V + E D + +++E + ++ V +E + +V +
Sbjct: 2253 KLVSEEIVTEEGSVAQEIVEEDAPATEEIDEIESVTEEVVEEEGPVDEEIVQEEGSVT-E 2311
Query: 312 ETAATDDTLSEKEKENGNLKTECSVESTSAIAAGYARQLSTEELAMSTDIEEDYKISEKD 133
E + + E +E G+ E VE SA + TEE+ ++ + +
Sbjct: 2312 EIIQGESKVEEVVEEQGSENEEIFVEEVSASQEIVQNESGTEEILEKVSASQEI-VQDGS 2370
Query: 132 IVSHLLQEQVHDKDEVVGETIHATDTVNKDET 37
+ +++EQ +EVV E T + ++E+
Sbjct: 2371 VTEQIIEEQKPVTEEVVNEEESITHEIIQEES 2402
Score = 110 bits (275), Expect = 4e-21
Identities = 228/1234 (18%), Positives = 511/1234 (41%), Gaps = 83/1234 (6%)
Frame = -3
Query: 3456 SVNQGVCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNKKCTA 3277
SV + + S + ++E +E+ + + E + + + E +V NVV + +
Sbjct: 522 SVTEDIVQEPSLAQEVEQKESDTNEI----EETKLANEKIIPEVSVTENVV--EKEGLDT 575
Query: 3276 GSLLEKKDNV--EVVIPSVKVRKKRDPASCSKTISSCKPRKASINKTNENLNMPSTQINK 3103
+LE+ +++ E+V V ++ S + + ++S + E + + +
Sbjct: 576 EEVLEEDESITEEIVEEEVSACEEIVEEEESSSEEIVEEEESSSEEIVEEESSSEEIVEE 635
Query: 3102 QELAGVIVLSD--NSDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSFANDA 2929
+E + ++ + ++++ +G V E + +T+ + I S E E F +
Sbjct: 636 EESSSEEIIEEVSSTEEVLEEEGSVTEEIVEEEVSTTEEVKDIGSVSEEVLEEEGFGTEE 695
Query: 2928 ALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQEESSGANDVAVNEKLKASDIEK 2749
+ + +++ T+ +TE VL+D S+ I QEE A ++ V+E++ ++
Sbjct: 696 FVGQQGSVIEEIVETESSTEK-VLEDVG--SNVEEIVQEEGPVAQEI-VHEEVSTTEKHD 751
Query: 2748 GVDTTVKDANHTKKGNVS--IMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATAINAATH 2575
VD + + K G+VS I+V + + + + S+ E++ + + + T
Sbjct: 752 EVDRSTTEEIVEKVGSVSEEIIVEEVSASEEIVEEGSVTEEVVEEEKLINEVGETESVTE 811
Query: 2574 -LEKKNIGNTLQALDVENKNVEVTIE----------------------GKIQGKAKRSES 2464
+ +K + + + L E E +E G + K E
Sbjct: 812 EIVQKEVSDAEEVLGQEGSMNEEILEKESIVEEIVGPEGSVTEEIVDHGSFAEEVKEEEL 871
Query: 2463 KTCSSEKKNIGNTLQALDEENKNVEVTIDRK-----IQGKGKRSESKTGSIPVMVAGCVN 2299
T + + T + +EE+ I+ I+ KG ++ + VN
Sbjct: 872 VTEEAVQYEGSVTEEIKEEESITENEAIEESAFAEIIEEKGPNTDEIVKEEGLDTEEIVN 931
Query: 2298 KASCEKFNQSAKEFTMSTDVLKDAKVFEKDV-----ATHQL--------EKGSGSNDVVI 2158
+ S ++ V ++ V EK V AT L EK S
Sbjct: 932 EVSVTDEVIEEEKLVNEQIVGEERSVTEKPVEVERSATEDLVEEEASVTEKVSVHEGSTT 991
Query: 2157 DKNINAKVAVEKVDTEINV--AVFTEKGSISNTLH----ILEDINKKKEATNEEKLPEKG 1996
++ ++ VA E V+ E++V + E+ S+ + ++E+I +++E+ EE L E+
Sbjct: 992 EQILDESVAEEIVEEEVSVDDKIIEEEVSVDEVVEEEGSVIEEIVEEEESVPEEILEEEL 1051
Query: 1995 ELSAELKPDSDSRSEFVATCVNEVSGQVNNLSIEEFTMSRDRPEDAEIFKETVGTH--QL 1822
S E+ D F+ V ++ + E +++ + ED ++ V ++
Sbjct: 1052 SGSEEVLEDEWVTDAFMGQ-EGSVIEEIEEIVDGEGSITEEIVEDGSANEKIVEEEPSRV 1110
Query: 1821 EEKVGSTYAVPSGEKRDVNLILKEVVTAANDSNLTEE-KTISNTAHTADDVRKEMEVAIE 1645
EE +G +++E++ + E+ KT+S + + + + EV E
Sbjct: 1111 EEVLGKE-----------GFVIEEIIEEGSVIEQVEDTKTVSEKSEESSAIEEVKEVKEE 1159
Query: 1644 ERMQEKGVSYSEKKAGTKSDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHAS- 1468
E + EK V E V E + + +T+K+ DV+ E+ S
Sbjct: 1160 ESISEKIVEKEES------------VTEEIVRQEESTTEKIV--KDVSPTEDFVEQTDSV 1205
Query: 1467 TDHLQEQISDTNEAA--VDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKST 1294
T+ + EQ E A V++K + D ++ D ++N + EKK ++ +I D+ +++
Sbjct: 1206 TEKVIEQEGSNTEVAEDVEEKESASDEHEQEDVSVNAQVTYEKKSVTK--EIVDEVSRTE 1263
Query: 1293 GITAE---------------ENMLEKGKLNSEIKTDR--TSEILAGRSDEERDQVSQFST 1165
I E E ++E+ + E+ D T E++ S + T
Sbjct: 1264 EIVEENGSVTEGVDETGSVTEEIIEEATVTEEVVEDGSVTEEVVEDGSVIQEVVEDGSVT 1323
Query: 1164 EELLMCSGTVKDPNNFEKCSVSHRRQEQIGHKNDNAVIENLQAYAVNNCDTGAKDGNFTE 985
EE++ +G+V + E+ SV+ +E++ + ++ + + G+++G+ +E
Sbjct: 1324 EEIVQENGSVTEEIVEEEGSVNEEVEEEVSVSGE---VDETEYVTEEVEEEGSEEGSVSE 1380
Query: 984 KENASKIVSS-LHEDIKCTTEVR----IAGELHEKRDLKSEFKANTTL-ETVGGCVNEKS 823
+ +++V+ + E T EV + E+ E + + + ++ E+V +
Sbjct: 1381 VVDETELVNDEIVEQAPFTEEVEEQVSVNDEIIEDASVAEAVEESESITESVSQEEETEK 1440
Query: 822 RHVSQLSTEVLAMSSEMAEDAKVVGTDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCP 643
V + E A++ E+ +D ++T ++ E S N ++++ + +E +
Sbjct: 1441 GFVIEKVEETGAVTEEIVQDG------LITEEILEESESVNGEIINKESDAEEILETEF- 1493
Query: 642 PTGDEKVGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVARFVNEESGYARQLP 463
+E VG + E IV++E ++ ++++EK E V + +E +L
Sbjct: 1494 -LTEEVVGQAGST--SEEIVEEEGSVTKEVEEK---------ESVTEELVDEGSVTEELV 1541
Query: 462 TEKLAMSTDTVGDYKISEKDIVSHLS-QEQIHDKDEVVDETIHATDTVNKDETAATDDTL 286
E +++ + V + ++E+ + S ++I +++ +E I D N +E + +
Sbjct: 1542 DEG-SVTEELVDEGSVTEEVVEQGGSIAQEIVEEESATEEIIR--DETNVEEVLEKEGSA 1598
Query: 285 SEKEKENGNLKTECSVESTSAIAAGYARQLSTEELAMSTDIEEDYKISEKDIVSHLLQEQ 106
+E+ ++G+ + + S I ++ST E + + + E++ + + E+
Sbjct: 1599 TEEIVQDGSGTNDFVGKQGSVIEEVVEEEISTTEEKLKEEASAIEEFVEEESIREDVLEE 1658
Query: 105 VHDKDEVVGETIHATDTVNKDETAATDDTLSEKE 4
+ VVG+ T+ + E + T+D + E+E
Sbjct: 1659 SLVTENVVGQQESVTEEIVDGEGSFTEDIVEEEE 1692
Score = 105 bits (263), Expect = 1e-19
Identities = 251/1283 (19%), Positives = 514/1283 (40%), Gaps = 127/1283 (9%)
Frame = -3
Query: 3468 EKTGSVNQGVCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNK 3289
E+ GS +G+ ++ I + VT E+ + T ++ I+ V+ D
Sbjct: 1796 EEEGSATEGIVEDRLATEGIVDD----ILVTEEIVEDGLATDEFVEQQGSIIEEVLDDEG 1851
Query: 3288 KCTAGSLLEKKDNVEVVIPSVKVRKKRDPAS-CSKTISSCKPRKASINKTNEN---LNMP 3121
T + E+ E ++ V V ++ D S+ I + I + EN L+
Sbjct: 1852 SVTEEIVEEEGSPNEEIVEGVSVIEEDDNIEPVSEEIVEGSVTEEMIKEGLENEVILDED 1911
Query: 3120 STQINKQELAG-----VIVLSDNSDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQ 2956
S E G ++ + + V + + + + +G+ S + ++ S E
Sbjct: 1912 SITEEALEKEGSVSEEIVEEMGSLTEEIVDEERSTSEDMIEEGSASEEIIQEESQVEEVV 1971
Query: 2955 ERNSFANDAALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQEESSGANDVAVNE 2776
E S ++ +L + ++ + TE V +E+ S I QEE G+ + + E
Sbjct: 1972 EEVSVIDEIVEEDELDTKEVVEEIEFNTEEVVEHKEEEGSVAEEIVQEEKEGSVNEEIIE 2031
Query: 2775 KLKASDIEKGVDTTVKDANHT--KKGNVSIMVGPIKQQKNVAK-GISMNEKMKGKGSVAK 2605
++ S E+ V+ V D ++ + + +K V + G+ E + + SV++
Sbjct: 2032 EV-GSITEEMVEQDVSDNEEIVEERSVIEEAEENVWIEKEVEEEGLDNEEVIDEEDSVSE 2090
Query: 2604 NATA---INAATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSSEKKNI 2434
A IN E ++ + + VEN+ + + + Q A+ +E E K +
Sbjct: 2091 QAEEEVYINEEILKESSDV----EDVKVENELMNEEVNEETQSVAENNE------EDKEL 2140
Query: 2433 GNTLQALDEENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFT 2254
N + + E+ EV +D ++ + E ++ ++ G + +E
Sbjct: 2141 DNYVVE-ETESVTEEVVVD-EVPNSKEVQEIESIIEEIVEDGLTTDDLVGQQGSVIEEVV 2198
Query: 2253 MSTDVLKDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTE--------INVA 2098
+ V E + +K S + D+++++++ + VE TE ++
Sbjct: 2199 EEVGSDSEEIVEEASITEEVEKKESVTEDILVEESVTGDILVEGSVTEEVVGEEKLVSEE 2258
Query: 2097 VFTEKGSISNTLHILEDINKKKE-----ATNEEKLPEKGELSAELKPDSDSRSEF----- 1948
+ TE+GS++ + + ED +E + EE + E+G + E+ + S +E
Sbjct: 2259 IVTEEGSVAQEI-VEEDAPATEEIDEIESVTEEVVEEEGPVDEEIVQEEGSVTEEIIQGE 2317
Query: 1947 --VATCVNEVSGQVNNLSIEEFTMSRDRPEDAEIFKETVGTHQLEEKVGSTYA-VPSGEK 1777
V V E + + +EE + S+ EI + GT ++ EKV ++ V G
Sbjct: 2318 SKVEEVVEEQGSENEEIFVEEVSASQ------EIVQNESGTEEILEKVSASQEIVQDGSV 2371
Query: 1776 RDVNLILKEVVT--AANDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEK- 1606
+ + ++ VT N+ + I +H V++ ++ E + E VS +E+
Sbjct: 2372 TEQIIEEQKPVTEEVVNEEESITHEIIQEESHVEKVVQQG---SVAEEVVENPVSVTEEI 2428
Query: 1605 --KAGTKSDTVGGR-VDEMSGQGSQLSTKKLAISSDV----------------AVDPKMF 1483
K G+ ++ +G + E ++ +K +++ +V +V+ ++
Sbjct: 2429 VEKEGSVTEDIGQEEIKEEQLDSEEIKEQKGSVNEEVVEEEGSVTEEIKEQEESVNEEVL 2488
Query: 1482 EKHASTDHLQEQI--------------SDTNEAAVDDKINPEDMMKKVDTAINDAIFTEK 1345
E+ T+ ++E+I SDT E ++ I+ E ++ DA
Sbjct: 2489 EEVEETESIKEEIVEGGIATQEIIEEESDTKEVVEEEVIDSEKLV--------DAGSVTG 2540
Query: 1344 KIISNIIQISDDENKSTGITAEENMLEKGKLNSEIKTDR-TSEILAGRSDEERDQVSQF- 1171
+++ + ++D E G T EE + E+ +N E+ D T + G ++V +
Sbjct: 2541 EVMPEEVSVTD-EVVEEGSTTEEVLEEQKSVNEEVVEDGLTIDDFVGLQGSTTEEVVEED 2599
Query: 1170 -STEELLMCSGTVKDPNNFEKCSVSHRRQEQIGHKNDNAVIENLQAYAVNNCDTGAKDGN 994
S E ++ T + ++ SV+ E+ G N+ + E A + + G+
Sbjct: 2600 GSAIEKILEEETATEEIVEKQVSVTEDIVEKEGSVNEEIIEEASVAEEI------IQGGS 2653
Query: 993 FTEKENASKIVSSLHEDIKCTTEVRIAGELHEKRDLKSEFKANTTLETVGGCVNEKSRHV 814
FTE E + S+ E I E I+ E+ E+ + + +E V V+++ V
Sbjct: 2654 FTE-EIVGQEESATEEVID--EEGLISNEIEEEEEKSVTEEMIEEVEEVS--VDDEVEEV 2708
Query: 813 SQLSTEVLAMSSEMAEDAKVVGTDVVTYQLQEPSGDTNQVVVDEAVNKD-----EAAAKD 649
S + EV +S + D V V L++ + + V D++V D + +D
Sbjct: 2709 S-VDDEVEEVSVKSVTDEIVQEESVCEEILEQEVSASEEYVDDKSVTDDFVGHERSVIQD 2767
Query: 648 CPPTGD--EKVGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAAS-EIVARFVNEESGY 478
T E++ + S+ EE + K+ + +EK+QE + E V + E
Sbjct: 2768 VENTESVTEEIAEVDKSVIEEAVEKQGSVTEEKVQEGVSAIEEIEEIESVTEEIEEIESV 2827
Query: 477 ARQLP-----TEKLAMSTDTVGDYKISEK-DIVSHLSQEQIHDKDEVVDETIHATDTVN- 319
++ TE++A +V + + ++ + + +E+ D +EV+++ D V
Sbjct: 2828 TEEIEEIESVTEEIAEEDKSVIEEAVEKQGSVTEEIVEEEELDTEEVLEDKSVTGDVVEQ 2887
Query: 318 ----KDETAA-------TDDTLSEKEKENGNLKTECSVESTSAIAAGYARQLS-----TE 187
KDE+ A D+ S KE++ +E SA ++LS E
Sbjct: 2888 EGSGKDESEAKESFTEEVDELKSVKEEDQETEYISREIEEESATEQHSEQELSINKEVVE 2947
Query: 186 ELAMSTDIEEDYK----------------ISEKDIVSHLLQEQVHDKDEVVGETIHATDT 55
+++ DIEE+ + E+ +L+E+V +EV+ E T+
Sbjct: 2948 TESLTKDIEEEKSTTQEILEETQSVNEEIVEEERDTDEVLKEKVSPSEEVIEEQASTTEE 3007
Query: 54 V-----NKDETAATDDTLSEKEK 1
+ DE +D +E+ K
Sbjct: 3008 FVEERSSTDEIVEVEDLFTEEVK 3030
Score = 104 bits (259), Expect = 3e-19
Identities = 181/985 (18%), Positives = 395/985 (40%), Gaps = 76/985 (7%)
Frame = -3
Query: 2733 VKDANHTKK-GNVSIMVGPIKQQKNVAKGIS---MNEKMKGKGSVAKNATAINAATHLEK 2566
VK+A+ T++ + + G +++ +++ I + E +K + + A A+ + EK
Sbjct: 37 VKEASITEEVEQIEPVTGKVEKIESITDEIKEQLVPEDIKEEQLDFEEIVAQRASVNDEK 96
Query: 2565 KNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSSEKKNIGNTLQALDEENKNVEV 2386
+ + + ++ E K+V + E + ++EK G++ + + EE +V
Sbjct: 97 VEVASITEEVEEEEKSVSEEV----------LEEEGSTTEKVVEGSSTEVVVEEQGSVSE 146
Query: 2385 TIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDVLKDAKVFEKDV 2206
+ ++ +G +E + + + S + +EF D +KD VFEK+
Sbjct: 147 EV---LEEEGSTTEEVVEEQGSVTENLLEEESASQGIVEKEEFVDEEDSVKDQNVFEKE- 202
Query: 2205 ATHQLEKGSGSNDVVIDKN--INAKVAVEKVDTEINVAVFTEKGSISNTLHILEDINKKK 2032
GS + +V ++ IN E++ TE++ + + I T E+I K++
Sbjct: 203 -------GSVTEQLVEEEKGLINEDNEKEELITEMSEEIKSVNEEIEETDLSTEEIIKQQ 255
Query: 2031 EATNEEKLPEKGELSAELKPDSDSRSEFVATCVNEVSGQVNNLSIEEFTMSRDRPEDAEI 1852
E + E+ L+ +L + E T ++ +S+ E + ++ E+
Sbjct: 256 GLATYEFVEEEKSLTDKLLEEESVTKEVGETELSTQEVVDEKVSVTEEVIEEEKSVSEEV 315
Query: 1851 FKETVGTHQLEEKVGSTYAVPSGEKRDVNLILKEVVTAANDSNLTEEKTISNTAHTADDV 1672
+E T ++ E+ GS + + D ++++E + + EE + + V
Sbjct: 316 LEEGSATEEVVEE-GSCTEIVVEKGSDTEIVVEE---GSATEIVVEEGSATEVVVEEGSV 371
Query: 1671 RKEM---EVAIEERMQEKGVSYS--EKKAGTKSDTVGGRVDEMSGQGSQLSTKKLAISSD 1507
+EM E + E + E+G+S +K G + G + + + +K+ +
Sbjct: 372 SEEMLEEEGSATEEVVEEGLSSDNVQKSKGVIENV--GEIYSVKTAKDESMNEKIPLEKS 429
Query: 1506 VAVDPKMFEKHASTDHLQEQISDTNEAAVDDKINPEDMMK-------------------- 1387
VD + F+ TD++ + D N + ++ P + K
Sbjct: 430 SFVDDESFKGQGPTDNVS--VEDVNSEDIINEHTPLEETKIEELPTEYITTADIHTKGET 487
Query: 1386 ---------KVDTAINDAIFTEKKIISNII----QISDD------------ENKSTGITA 1282
K++ + A F E+KI NI +++D + +S
Sbjct: 488 ETKYNLIYEKINEEVEKAKFQEEKITENIPVERESVTEDIVQEPSLAQEVEQKESDTNEI 547
Query: 1281 EENMLEKGKLNSEIKTDRTSEILAGRSDEERDQVSQFSTEELL-----MCSGTVKDPNNF 1117
EE L K+ E+ G EE + + TEE++ C V++ +
Sbjct: 548 EETKLANEKIIPEVSVTENVVEKEGLDTEEVLEEDESITEEIVEEEVSACEEIVEEEESS 607
Query: 1116 EKCSVSHRRQEQIGHKNDNAVIENLQAYAVNNCDTGAKDGNFTEK---ENASKIVSSLHE 946
+ V + + E + ++ + ++ + TE+ E S + E
Sbjct: 608 SEEIVEEEESSSEEIVEEESSSEEIVEEEESSSEEIIEEVSSTEEVLEEEGSVTEEIVEE 667
Query: 945 DIKCTTEVRIAGELHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAE 766
++ T EV+ G + E+ LE G E + E++ S +
Sbjct: 668 EVSTTEEVKDIGSVSEE-----------VLEEEGFGTEEFVGQQGSVIEEIVETESSTEK 716
Query: 765 DAKVVGTDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEENI 586
+ VG++V ++ + G Q +V E V+ E + T +E V + S+ EE I
Sbjct: 717 VLEDVGSNVE--EIVQEEGPVAQEIVHEEVSTTEKHDEVDRSTTEEIVEKVG-SVSEEII 773
Query: 585 VKKETAIDEKMQEKWQLKADAASEIVARFVNEESGYARQLPTEKLAMSTDTVG-----DY 421
V++ +A +E ++E + E + V E ++ ++++ + + +G +
Sbjct: 774 VEEVSASEEIVEEGSVTEEVVEEEKLINEVGETESVTEEIVQKEVSDAEEVLGQEGSMNE 833
Query: 420 KISEKD-IVSHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTEC 244
+I EK+ IV + + +E+VD A + K+E T++ + + +K E
Sbjct: 834 EILEKESIVEEIVGPEGSVTEEIVDHGSFAEEV--KEEELVTEEAVQYEGSVTEEIKEEE 891
Query: 243 SVESTSAIAAGYARQL------STEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKDEVV 82
S+ AI ++ +T+E+ ++ + ++E + +++E+ +++V
Sbjct: 892 SITENEAIEESAFAEIIEEKGPNTDEIVKEEGLDTEEIVNEVSVTDEVIEEEKLVNEQIV 951
Query: 81 GETIHATDTVNKDETAATDDTLSEK 7
GE T+ + E +AT+D + E+
Sbjct: 952 GEERSVTEKPVEVERSATEDLVEEE 976
>gb|ETW41847.1| hypothetical protein PFNF135_03775 [Plasmodium falciparum
NF135/5.C10]
Length = 4385
Score = 116 bits (291), Expect = 6e-23
Identities = 247/1236 (19%), Positives = 507/1236 (41%), Gaps = 85/1236 (6%)
Frame = -3
Query: 3459 GSVNQGVCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVV---IGDNK 3289
GSV + V S + E E +T +R E + V + LEKE + +V G N
Sbjct: 1877 GSVTEEVVEQGGSIAQ-EIVEEESATEEIIRDETN-VEEVLEKEGSATEEIVQDGSGTND 1934
Query: 3288 KC-TAGSLLEKKDNVEVVIPSVKVRKKRDPASCSKTISSCKPRKASINKT--NENLNMPS 3118
GS++E+ VE I + + + K + ++ + + R+ + ++ EN+
Sbjct: 1935 FVGKQGSVIEEV--VEEEISTTEEKLKEEASAIEEFVEEESIREDVLEESLVTENVVGQQ 1992
Query: 3117 TQINKQELAGVIVLSDN--SDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNS 2944
+ ++ + G +++ ++ +V++ V + +V K +++ T E ++ S
Sbjct: 1993 ESVTEEIVDGEGSFTEDIVEEEESVTEEIVVDEESVTKEIVEDEELV---TEEIVEDEGS 2049
Query: 2943 FANDAALNAKLQGSDKMKNTDVATEN---CVLKDK-EKVSHTSNISQEESSGANDVAVNE 2776
F + L +++++T+ E V+K+ ++ S T I +EE S +V E
Sbjct: 2050 FTEEVIEERSL--IEEVEDTETVAEKEEGSVIKEIIDEKSLTEKIVEEEKSVTEEVEEKE 2107
Query: 2775 KLKASDIEKGVDTTVKDANHTKKGNVS-------IMVGPIKQQKNVAKGISMNEKMKGKG 2617
+K E+ + V++ +G V I+ + ++ V G++ +E ++ +G
Sbjct: 2108 SVKEEVEEQRL--VVEEEGSATEGIVEDRLATEGIVDDILVTEEIVEDGLATDEFVEQQG 2165
Query: 2616 SVAKNATAINAATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSSEKKN 2437
S+ + + T + ++ E E +EG + ++ SE+
Sbjct: 2166 SIIEEVLDDEGSV---------TEEIVEEEGSPNEEIVEGV--SVIEEDDNIEPVSEEIV 2214
Query: 2436 IGNTLQALDEENKNVEVTIDR-KIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKE 2260
G+ + + +E EV +D I + E V G + + ++ +S E
Sbjct: 2215 EGSVTEEMIKEGLENEVILDEDSITEEALEKEGSVSEEIVEEMGSLTEEIVDE-ERSTSE 2273
Query: 2259 FTMSTDVLKDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVD--TEINVAVFTE 2086
+ + + E+ +E+ S +++V + ++ K VE+++ TE V E
Sbjct: 2274 DMIEEGSASEEIIQEESQVEEVVEEVSVIDEIVEEDELDTKEVVEEIEFNTEEVVEHKEE 2333
Query: 2085 KGSISNTLHILEDINKKKEAT-NEEKLPEKGELSAELKPDSDSRSEFVATCVNEVSGQVN 1909
+GS++ E + ++KE + NEE + E G ++ E+ S +E + + +
Sbjct: 2334 EGSVAE-----EIVQEEKEGSVNEEIIEEVGSITEEMVEQDVSDNEEIVEERSVIEEAEE 2388
Query: 1908 NLSIEEFTMSRDRPEDAEIFKETVGTHQLEEKVGSTYAV--PSGEKRDV---NLILKEVV 1744
N+ IE+ + I +E + Q EE+V + S + DV N ++ E V
Sbjct: 2389 NVWIEKEVEEEGLDNEEVIDEEDSVSEQAEEEVYINEEILKESSDVEDVKVENELMNEEV 2448
Query: 1743 TAANDS---NLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAGTKSDTVGG 1573
S N E+K + N + E EV ++E K V E + G
Sbjct: 2449 NEETQSVAENNEEDKELDNYVVEETESVTE-EVVVDEVPNSKEVQEIESIIEEIVED-GL 2506
Query: 1572 RVDEMSGQ-GSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDTNEAAVDDKINPED 1396
D++ GQ GS + + SD ++ E+ + T+ ++++ S T + V++ + +
Sbjct: 2507 TTDDLVGQQGSVIEEVVEEVGSD---SEEIVEEASITEEVEKKESVTEDILVEESVTGDI 2563
Query: 1395 MMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGITAEENMLEKGKLNSEIKTDR--TS 1222
+ V+ ++ + + E+K++S I + G A+E + E EI T
Sbjct: 2564 L---VEGSVTEEVVGEEKLVSEEIVTEE------GSVAQEIVEEDAPATEEIDEIESVTE 2614
Query: 1221 EILA--GRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKCSVSHRRQEQIGHKNDNAVIE 1048
E++ G DEE Q TEE++ V++ E+ G +N+ +E
Sbjct: 2615 EVVEEEGPVDEEIVQEEGSVTEEIIQGESKVEEV------------VEEQGSENEEIFVE 2662
Query: 1047 NLQA---YAVNNCDTGAKDGNFTE--KENASKIVSSLHEDIKCTTEVR------------ 919
+ A N + ++G+ TE KE + + E+++ T ++
Sbjct: 2663 EVSASQEIVQNESEVVEEEGSVTEEIKEQEESVNEEVLEEVEETESIKEEIVEGGIATQE 2722
Query: 918 -IAGELHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSS---EMAEDAKVV 751
I E K ++ E + L G E ++ EV+ S E+ E+ K V
Sbjct: 2723 IIEEESDTKEVVEEEVIDSEKLVDAGSVTGEVMPEEVSVTDEVVEEGSTTEEVLEEQKSV 2782
Query: 750 GTDVV----------------TYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGD--EK 625
+VV T ++ E G + +++E +E K T D EK
Sbjct: 2783 NEEVVEDGLTIDDFVGLQGSTTEEVVEEDGSAIEKILEEETATEEIVEKQVSVTEDIVEK 2842
Query: 624 VGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVARFVNEESGYARQLP------ 463
G++ + EE V +E E+ + ++A+E V ++EE + ++
Sbjct: 2843 EGSVNEEIIEEASVAEEIIQGGSFTEEIVGQEESATEEV---IDEEGLISNEIEEEEEKS 2899
Query: 462 -TEKLAMSTDTVG-DYKISEKDIVSHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDT 289
TE++ + V D ++ E + + +E++ D DE++ E + AT+ V ++ + TD+
Sbjct: 2900 VTEEMIEEVEEVSVDDEVEEVSVAEEIVEEELVD-DEILPEELSATEDVIEEVRSVTDEI 2958
Query: 288 LSEKEKENGNLKTECSVESTSAIAAGYARQLSTEELAMSTDIEEDYKISEK--DIVSHLL 115
+ E+ L+ E S E ++ D+E ++E+ ++ ++
Sbjct: 2959 VQEESVCEEILEQEVSASEEYVDDKSVTDDFVGHERSVIQDVENTESVTEEIAEVDKSVI 3018
Query: 114 QEQVHDKDEVVGETIHATDTVNKDETAATDDTLSEK 7
+E V + V E V ++E T++ L +K
Sbjct: 3019 EEAVEKQGSVTEE------KVQEEEELDTEEVLEDK 3048
Score = 114 bits (286), Expect = 2e-22
Identities = 234/1212 (19%), Positives = 496/1212 (40%), Gaps = 59/1212 (4%)
Frame = -3
Query: 3468 EKTGSVNQGVCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNK 3289
E+ GSVN+ V S S +++ E V S V + + +E + VV D
Sbjct: 1659 EEEGSVNEEVEEEVSVSGEVDETEYVTEEVEEEGSVEGSVVEEIVEEEGSVSEVV--DET 1716
Query: 3288 KCTAGSLLEKKDNVEVVIPSVKVRKKR-DPASCSKTISSCKPRKASINKTNENLNMPSTQ 3112
+ ++E+ E V V V + + AS ++ + + S+++ E
Sbjct: 1717 ELVNDEIVEQAPFTEEVEEQVSVNDEIIEDASVAEAVEESESITESVSQEEETEK----- 1771
Query: 3111 INKQELAGVIVLSDNSDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSFAND 2932
G ++ KV+E GA + + V+ E E + N
Sbjct: 1772 -------GFVI------------EKVEET-----GAVTEEIVQDGLITEEILEESESVNG 1807
Query: 2931 AALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQEESSGANDVAVNEKLKASDIE 2752
+N K ++++ T+ TE V + S + I +EE S +V E + ++
Sbjct: 1808 EIIN-KESDAEEILETEFLTEEVV---GQAGSTSEEIVEEEGSVTKEVEEKESVTEELVD 1863
Query: 2751 KGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATAINAATHL 2572
+G + ++ +G+V+ V ++Q ++A+ I E+ + ++ T N L
Sbjct: 1864 EGSVSVTEEL--VDEGSVTEEV--VEQGGSIAQEIV--EEESATEEIIRDET--NVEEVL 1915
Query: 2571 EKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSSEKKNIGNTLQALDEENKNV 2392
EK+ D N V +G + + E T + K + ++ EE
Sbjct: 1916 EKEGSATEEIVQDGSGTNDFVGKQGSVIEEVVEEEISTTEEKLKEEASAIEEFVEEESIR 1975
Query: 2391 EVTIDRKIQGKGK--RSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDVLKDAKVF 2218
E ++ + + + ES T I V G + E+ +E + + + V
Sbjct: 1976 EDVLEESLVTENVVGQQESVTEEI-VDGEGSFTEDIVEEEESVTEEIVVDEESVTKEIVE 2034
Query: 2217 EKDVATHQL--EKGSGSNDVVIDKNI-----NAKVAVEKVDTEINVAVFTEKGSISNTLH 2059
++++ T ++ ++GS + +V+ ++++ + + EK + + + EK +
Sbjct: 2035 DEELVTEEIVEDEGSFTEEVIEERSLIEEVEDTETVAEKEEGSVIKEIIDEKSLTEKIVE 2094
Query: 2058 ----ILEDINKK---KEATNEEKL--PEKGELSAELKPDSDSRSEFVATCVNEVSGQVNN 1906
+ E++ +K KE E++L E+G + + D + V + +
Sbjct: 2095 EEKSVTEEVEEKESVKEEVEEQRLVVEEEGSATEGIVEDRLATEGIVDDILVTEEIVEDG 2154
Query: 1905 LSIEEFTMSRDRPEDAEIFKETVGTHQLEEKVGS-TYAVPSG-----EKRDVNLILKEVV 1744
L+ +EF + + + E T ++ E+ GS + G E ++ + +E+V
Sbjct: 2155 LATDEFVEQQGSIIEEVLDDEGSVTEEIVEEEGSPNEEIVEGVSVIEEDDNIEPVSEEIV 2214
Query: 1743 TAANDSNLTEEKTISNTAHTADDVRKEM---EVAIEERMQEKGVSYSEK----KAGTKSD 1585
+ + +E + D + +E E ++ E + E+ S +E+ + T D
Sbjct: 2215 EGSVTEEMIKEGLENEVILDEDSITEEALEKEGSVSEEIVEEMGSLTEEIVDEERSTSED 2274
Query: 1584 TV--GGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDTNEAAVDDK 1411
+ G +E+ + SQ+ +S +D + E T + E+I E V+ K
Sbjct: 2275 MIEEGSASEEIIQEESQVEEVVEEVS---VIDEIVEEDELDTKEVVEEIEFNTEEVVEHK 2331
Query: 1410 -----INPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGITAEENMLEKGKLNS 1246
+ E + ++ + ++N+ I E I+ + + D + + I E +++E+ + N
Sbjct: 2332 EEEGSVAEEIVQEEKEGSVNEEIIEEVGSITEEM-VEQDVSDNEEIVEERSVIEEAEENV 2390
Query: 1245 EIKTDRTSEILAGRSD-EERDQVSQFSTEELLMCSGTVKDPNNFEKCSVSHRRQEQIGHK 1069
I+ + E L +E D VS+ + EE+ + +K+ ++ E V + +
Sbjct: 2391 WIEKEVEEEGLDNEEVIDEEDSVSEQAEEEVYINEEILKESSDVEDVKVENELMNE---- 2446
Query: 1068 NDNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCTTEVRIAGELHEKRD 889
V E Q+ A NN + D E+ S+ E++ EV + E+ E
Sbjct: 2447 ---EVNEETQSVAENNEEDKELDNYVVEE------TESVTEEV-VVDEVPNSKEVQEIES 2496
Query: 888 LKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVGTDVVTYQLQEPSG 709
+ E + T V ++ + ++ EV + S E+ E+A + T ++++
Sbjct: 2497 IIEEIVEDGL--TTDDLVGQQGSVIEEVVEEVGSDSEEIVEEASI------TEEVEKKES 2548
Query: 708 DTNQVVVDEAVNKD---EAAAKDCPPTGDEKVGNIAYSLYEENIVKKETAIDEKMQEKWQ 538
T ++V+E+V D E + + G+EK L E IV +E ++ +++ E+
Sbjct: 2549 VTEDILVEESVTGDILVEGSVTE-EVVGEEK-------LVSEEIVTEEGSVAQEIVEEDA 2600
Query: 537 LKADAASEIVA---RFVNEESGYARQLPTEKLAMSTDTV-GDYKI----------SEKDI 400
+ EI + V EE ++ E+ +++ + + G+ K+ +E+
Sbjct: 2601 PATEEIDEIESVTEEVVEEEGPVDEEIVQEEGSVTEEIIQGESKVEEVVEEQGSENEEIF 2660
Query: 399 VSHLS--QEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVESTS 226
V +S QE + ++ EVV+E T+ + + E + ++ L E E E ++K E VE
Sbjct: 2661 VEEVSASQEIVQNESEVVEEEGSVTEEIKEQEESVNEEVLEEVE-ETESIKEEI-VEGGI 2718
Query: 225 AIAAGYARQLSTEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDTVNK 46
A + T+E+ I+ + + + ++ E+V DEVV E T+ V +
Sbjct: 2719 ATQEIIEEESDTKEVVEEEVIDSEKLVDAGSVTGEVMPEEVSVTDEVVEEG-STTEEVLE 2777
Query: 45 DETAATDDTLSE 10
++ + ++ + +
Sbjct: 2778 EQKSVNEEVVED 2789
Score = 107 bits (266), Expect = 5e-20
Identities = 225/1168 (19%), Positives = 467/1168 (39%), Gaps = 17/1168 (1%)
Frame = -3
Query: 3459 GSVNQGVCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNKKCT 3280
GSV + + SS+ K+ E+ GS V + E V Q + E V + + T
Sbjct: 1011 GSVIEEIVETESSTEKV--LEDVGSNVEEIVQEEGPVAQEIVHEE-VSTTEKHDEVDRST 1067
Query: 3279 AGSLLEKKDNVEVVIPSVKVRKKRDPASCSKTISSCKPRKASINKTNENLNMPSTQINKQ 3100
++EK +V I +V + + IN+ E ++ + K+
Sbjct: 1068 TEEIVEKVGSVSEEIIVEEVSASEEIVEEGSVTEEVVEEEKLINEVGETESVTEEIVQKE 1127
Query: 3099 --ELAGVIVLSDNSDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSFANDAA 2926
+ V+ + ++ + K + E +G+ + + V S E +E +A
Sbjct: 1128 VSDAEEVLGQEGSMNEEILEKESIVEEIVGPEGSVTEEIVDHGSFAEEVKEEELVTEEAV 1187
Query: 2925 LNAKLQGS--DKMKNTDVATENCVLKDKEKVSHTSNISQEESSGANDVAVNEKLKASDIE 2752
+ +GS +++K + TEN +++ S + I +E+ +++ E L +I
Sbjct: 1188 ---QYEGSVTEEIKEEESITENEAIEE----SAFAEIIEEKGPNTDEIVKEEGLDTEEIV 1240
Query: 2751 KGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATAINAATHL 2572
V T + K N I + ++++V + E+ + V + A+ +
Sbjct: 1241 NEVSVTDEVIEEEKLVNEQI----VGEERSVTEKPVEVERSATEDLVEEEASVTEKVSVH 1296
Query: 2571 EKKNIGNTL-QALDVENKNVEVTIEGKIQGKAKRSESKTCSSEKKNIGNTLQALDEENKN 2395
E L +++ E EV+++ KI E + + G+ ++ + EE ++
Sbjct: 1297 EGSTTEQILDESVAEEIVEEEVSVDDKII-----EEEVSVDEVVEEEGSVIEEIVEEEES 1351
Query: 2394 V-EVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDVLKDAKVF 2218
V E ++ ++ G + E + + M G E E +++ ++++D
Sbjct: 1352 VPEEILEEELSGSEEVLEDEWVTDAFM--GQEGSVIEEIEEIVDGEGSITEEIVEDGSAN 1409
Query: 2217 EKDVATH--QLEKGSGSNDVVIDKNINAKVAVEKVDTEINVAVFTEKGSISNTLHILEDI 2044
EK V ++E+ G VI++ I +E+V+ V+ EK S+ + ++++
Sbjct: 1410 EKIVEEEPSRVEEVLGKEGFVIEEIIEEGSVIEQVEDTKTVS---EKSEESSAIEEVKEV 1466
Query: 2043 NKKKEATNEEKLPEKGE-LSAELKPDSDSRSEFVATCVNEVSGQVNNLSIEEFTMSRDRP 1867
K+E + EK+ EK E ++ E+ +S +E + V +VS E+F D
Sbjct: 1467 --KEEESISEKIVEKEESVTEEIVRQEESTTEKI---VKDVS------PTEDFVEQTDSV 1515
Query: 1866 EDAEIFKETVGTHQLEEKVGSTYAVPSGEKRDVNLILKEVVTAANDSNLTEEKTISNTAH 1687
+ I +E T E+ A E+ DV++ ++ +T EK S T
Sbjct: 1516 TEKVIEQEGSNTEVAEDVEEKESASDEHEQEDVSV----------NAQVTYEKK-SVTKE 1564
Query: 1686 TADDVRKEMEVAIEERMQEKGVSYSEKKAGTKSDTVGGRVDEMSGQGSQLSTKKLAISSD 1507
D+V + E+ E +GV D G +E+ + +T + D
Sbjct: 1565 IVDEVSRTEEIVEENGSVTEGV-----------DETGSVTEEIIEE----ATVTEEVVED 1609
Query: 1506 VAVDPKMFEKHASTDHLQEQISDTNEAAVDDKINPEDMMKKVDTAINDAIFTEKKIISNI 1327
+V ++ E + T+ + E S E D + E + + + ++ + I E+ ++
Sbjct: 1610 GSVTEEVVEDGSVTEEVVEDGSVIQEVVEDGSVTEEIVQE--NGSVTEEIVEEEGSVNE- 1666
Query: 1326 IQISDDENKSTGITAEENMLEKGKLNSEIKTDRTSEILAGRSDEERDQVSQFSTEELLMC 1147
++ ++ + S + E + E+ + ++ EI+ EE VS+ E L+
Sbjct: 1667 -EVEEEVSVSGEVDETEYVTEEVEEEGSVEGSVVEEIV-----EEEGSVSEVVDETELVN 1720
Query: 1146 SGTVKDPNNFEKCSVSHRRQEQIGHKNDNAVIENLQAYAVNNCDTGAKDGNFTEKENASK 967
V E+ + +EQ+ ND + + A AV ++ + + E+
Sbjct: 1721 DEIV------EQAPFTEEVEEQVS-VNDEIIEDASVAEAVEESESITESVSQEEETEKGF 1773
Query: 966 IVSSLHEDIKCTTEVRIAGELHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLA 787
++ + E T E+ G + E+ +SE G +N++S L TE L
Sbjct: 1774 VIEKVEETGAVTEEIVQDGLITEEILEESE-------SVNGEIINKESDAEEILETEFL- 1825
Query: 786 MSSEMAEDAKVVGTDVV------TYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGD-- 631
+ E+ A ++V T +++E T ++V + +V+ E + T +
Sbjct: 1826 -TEEVVGQAGSTSEEIVEEEGSVTKEVEEKESVTEELVDEGSVSVTEELVDEGSVTEEVV 1884
Query: 630 EKVGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVARFVNEESGYARQLPTEKL 451
E+ G+IA + EE +E DE E+ V E+ G A TE++
Sbjct: 1885 EQGGSIAQEIVEEESATEEIIRDETNVEE---------------VLEKEGSA----TEEI 1925
Query: 450 AMSTDTVGDYKISEKDIVSHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEK 271
D+ + ++ +EVV+E I T+ K+E +A ++ + E+
Sbjct: 1926 VQDGSGTNDFVGKQGSVI-----------EEVVEEEISTTEEKLKEEASAIEEFVEEESI 1974
Query: 270 ENGNLKTECSVESTSAIAAGYARQLSTEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKD 91
L+ E+ ++ E + + DI E+ E+ + ++ ++
Sbjct: 1975 REDVLEESLVTENVVGQQESVTEEIVDGEGSFTEDIVEE----EESVTEEIVVDEESVTK 2030
Query: 90 EVVGETIHATDTVNKDETAATDDTLSEK 7
E+V + T+ + +DE + T++ + E+
Sbjct: 2031 EIVEDEELVTEEIVEDEGSFTEEVIEER 2058
Score = 105 bits (263), Expect = 1e-19
Identities = 223/1109 (20%), Positives = 447/1109 (40%), Gaps = 89/1109 (8%)
Frame = -3
Query: 3063 DDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQERNSFANDAALNAKLQGSDKMKNT 2884
D+ V +G V E V +T+ + I S E E F + + + +++ T
Sbjct: 964 DEEIVDQGSVVENEEV---STTEEVKDIGSVSEEVLEEEGFGTEEFVGQQGSVIEEIVET 1020
Query: 2883 DVATENCVLKDKEKVSHTSNISQEESSGANDVAVNEKLKASDIEKGVDTTVKDANHTKKG 2704
+ +TE VL+D S+ I QEE A ++ V+E++ ++ VD + + K G
Sbjct: 1021 ESSTEK-VLEDVG--SNVEEIVQEEGPVAQEI-VHEEVSTTEKHDEVDRSTTEEIVEKVG 1076
Query: 2703 NVS--IMVGPIKQQKNVAKGISMNEKMKGKGSVAKNATAINAATH-LEKKNIGNTLQALD 2533
+VS I+V + + + + S+ E++ + + + T + +K + + + L
Sbjct: 1077 SVSEEIIVEEVSASEEIVEEGSVTEEVVEEEKLINEVGETESVTEEIVQKEVSDAEEVLG 1136
Query: 2532 VENKNVEVTIEGKIQGKAKRSESKTCSSEKKNIGNTLQALDEENKNVEVTIDRKIQGKGK 2353
E E +E + + + + E + G+ + + EE E+ + +Q +G
Sbjct: 1137 QEGSMNEEILEKESIVEEIVGPEGSVTEEIVDHGSFAEEVKEE----ELVTEEAVQYEGS 1192
Query: 2352 RSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDVLKDAKVFEKDVATHQLEKGSGS 2173
+E + + +++ F + +E +TD + V E+ + T ++
Sbjct: 1193 VTEEIKEEESITENEAIEESA---FAEIIEEKGPNTDEI----VKEEGLDTEEIVNEVSV 1245
Query: 2172 NDVVID--KNINAKVAVEK---VDTEINVAVFTEKGSISNTLHILEDINKKKEATNEEKL 2008
D VI+ K +N ++ E+ + + V + + + E ++ + +T E+ L
Sbjct: 1246 TDEVIEEEKLVNEQIVGEERSVTEKPVEVERSATEDLVEEEASVTEKVSVHEGSTTEQIL 1305
Query: 2007 PEK-GELSAELKPDSDSRSEFVATCVNEVSGQVNNLSIEEFTMSRDRPEDAEIFKETVGT 1831
E E E + D + V+EV + ++ IEE + + + +E G+
Sbjct: 1306 DESVAEEIVEEEVSVDDKIIEEEVSVDEVVEEEGSV-IEEIVEEEESVPEEILEEELSGS 1364
Query: 1830 HQLEEKVGSTYAVPSGEKRDVNLILKEVVTAANDSNLTEE---------KTISNTAHTAD 1678
++ E T A G++ V ++E+V + ++TEE K + +
Sbjct: 1365 EEVLEDEWVTDAF-MGQEGSVIEEIEEIVDG--EGSITEEIVEDGSANEKIVEEEPSRVE 1421
Query: 1677 DVRKEMEVAIEERMQEKGVSYSEKKAGTKSDTVGGRVDEMSGQGSQLSTKKLAISSDVAV 1498
+V + IEE ++E V E+ TK+ V E S + S + K + + ++
Sbjct: 1422 EVLGKEGFVIEEIIEEGSVI--EQVEDTKT------VSEKSEESSAIEEVK-EVKEEESI 1472
Query: 1497 DPKMFEKHAS-TDHLQEQISDTNEAAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQ 1321
K+ EK S T+ + Q T E V D ED +++ D+ I E SN
Sbjct: 1473 SEKIVEKEESVTEEIVRQEESTTEKIVKDVSPTEDFVEQTDSVTEKVIEQEG---SNTEV 1529
Query: 1320 ISDDENKSTGITAEEN---------MLEKGKLNSEI--KTDRTSEILAGRSD-----EER 1189
D E K + E EK + EI + RT EI+ +E
Sbjct: 1530 AEDVEEKESASDEHEQEDVSVNAQVTYEKKSVTKEIVDEVSRTEEIVEENGSVTEGVDET 1589
Query: 1188 DQVSQFSTEELLMCSGTVKDPNNFEKCSVSHRRQEQIGHKNDNAVIENLQAYAVNNCDTG 1009
V++ EE + V+D + E+ E++ D +VI+ +
Sbjct: 1590 GSVTEEIIEEATVTEEVVEDGSVTEEVVEDGSVTEEV--VEDGSVIQEV----------- 1636
Query: 1008 AKDGNFTEK---ENAS---KIVS---SLHEDIKCTTEVRIAGELHEKRDLKSEFKANTTL 856
+DG+ TE+ EN S +IV S++E+++ EV ++GE+ E + E + ++
Sbjct: 1637 VEDGSVTEEIVQENGSVTEEIVEEEGSVNEEVE--EEVSVSGEVDETEYVTEEVEEEGSV 1694
Query: 855 E-TVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVGTDVVTYQLQEPSGDTNQVVVDEA 679
E +V + E+ VS++ E ++ E+ E A T+ V Q+ V EA
Sbjct: 1695 EGSVVEEIVEEEGSVSEVVDETELVNDEIVEQAPF--TEEVEEQVSVNDEIIEDASVAEA 1752
Query: 678 VNKDEAAAKDCPPTGDEKVGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVARF 499
V + E+ + + + G + + E V +E D + E+ ++++ +
Sbjct: 1753 VEESESITESVSQEEETEKGFVIEKVEETGAVTEEIVQDGLITEEILEESESVN---GEI 1809
Query: 498 VNEESGYARQLPTEKLAMSTDTVGDYKISEKDIVSHLSQ--EQIHDKDEVVDETIHATDT 325
+N+ES L TE L + + VG + ++IV +++ +K+ V +E + +
Sbjct: 1810 INKESDAEEILETEFL--TEEVVGQAGSTSEEIVEEEGSVTKEVEEKESVTEELVDE-GS 1866
Query: 324 VNKDETAATDDTLSEKEKENGNLKTECSVESTSAIAAGYARQLS-----------TEELA 178
V+ E + +++E+ E G + VE SA + + TEE+
Sbjct: 1867 VSVTEELVDEGSVTEEVVEQGGSIAQEIVEEESATEEIIRDETNVEEVLEKEGSATEEIV 1926
Query: 177 MSTDIEEDYKISEKDIVSHLLQEQVHDKDE------------------------------ 88
D+ + ++ +++E++ +E
Sbjct: 1927 QDGSGTNDFVGKQGSVIEEVVEEEISTTEEKLKEEASAIEEFVEEESIREDVLEESLVTE 1986
Query: 87 -VVGETIHATDTVNKDETAATDDTLSEKE 4
VVG+ T+ + E + T+D + E+E
Sbjct: 1987 NVVGQQESVTEEIVDGEGSFTEDIVEEEE 2015
Score = 103 bits (256), Expect = 7e-19
Identities = 238/1212 (19%), Positives = 478/1212 (39%), Gaps = 59/1212 (4%)
Frame = -3
Query: 3468 EKTGSVNQGVCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNK 3289
E+ GS +G+ ++ I + VT E+ + T ++ I+ V+ D
Sbjct: 2121 EEEGSATEGIVEDRLATEGIVDD----ILVTEEIVEDGLATDEFVEQQGSIIEEVLDDEG 2176
Query: 3288 KCTAGSLLEKKDNVEVVIPSVKVRKKRDPAS-CSKTISSCKPRKASINKTNEN---LNMP 3121
T + E+ E ++ V V ++ D S+ I + I + EN L+
Sbjct: 2177 SVTEEIVEEEGSPNEEIVEGVSVIEEDDNIEPVSEEIVEGSVTEEMIKEGLENEVILDED 2236
Query: 3120 STQINKQELAG-----VIVLSDNSDDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQ 2956
S E G ++ + + V + + + + +G+ S + ++ S E
Sbjct: 2237 SITEEALEKEGSVSEEIVEEMGSLTEEIVDEERSTSEDMIEEGSASEEIIQEESQVEEVV 2296
Query: 2955 ERNSFANDAALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQEESSGANDVAVNE 2776
E S ++ +L + ++ + TE V +E+ S I QEE G+ VNE
Sbjct: 2297 EEVSVIDEIVEEDELDTKEVVEEIEFNTEEVVEHKEEEGSVAEEIVQEEKEGS----VNE 2352
Query: 2775 KLKASDIEKGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEKMKGKGSVAKNAT 2596
++ IE+ VG I ++ V + +S NE++ + SV + A
Sbjct: 2353 EI----IEE--------------------VGSITEEM-VEQDVSDNEEIVEERSVIEEAE 2387
Query: 2595 A-INAATHLEKKNIGNTLQALDVENK-----NVEVTIEGKIQGKAKRSESKTCSSEKKN- 2437
+ +E++ + N + +D E+ EV I +I ++ E +E N
Sbjct: 2388 ENVWIEKEVEEEGLDNE-EVIDEEDSVSEQAEEEVYINEEILKESSDVEDVKVENELMNE 2446
Query: 2436 -IGNTLQALDEENKNVEVTIDRKIQGKGKRSESKTGSIPV-MVAGCVNKASCEKFNQSAK 2263
+ Q++ E N+ + +D + + +ES T + V V E +
Sbjct: 2447 EVNEETQSVAENNEE-DKELDNYVV---EETESVTEEVVVDEVPNSKEVQEIESIIEEIV 2502
Query: 2262 EFTMSTDVL--KDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTEINVAVFT 2089
E ++TD L + V E+ V E GS S ++V + +I +V ++ TE + +
Sbjct: 2503 EDGLTTDDLVGQQGSVIEEVVE----EVGSDSEEIVEEASITEEVEKKESVTEDILVEES 2558
Query: 2088 EKGSISNTLHILEDINKKKEATNEEKLPEKGELSAELKPDSDSRSEFVATCVNEVSGQVN 1909
G I + E++ +++ +EE + E+G ++ E+ + +E + +E+
Sbjct: 2559 VTGDILVEGSVTEEVVGEEKLVSEEIVTEEGSVAQEIVEEDAPATEEI----DEIE---- 2610
Query: 1908 NLSIEEFTMSRDRPEDAEIFKE----TVGTHQLEEKVGSTYAVPSGEKRDVNLILKEVVT 1741
S+ E + + P D EI +E T Q E KV E + I E V+
Sbjct: 2611 --SVTEEVVEEEGPVDEEIVQEEGSVTEEIIQGESKVEEVVEEQGSENEE---IFVEEVS 2665
Query: 1740 AANDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAGTKSDTVGGRVDE 1561
A+ + E + + ++++++ E EE ++E + S K+ + + E
Sbjct: 2666 ASQEIVQNESEVVEEEGSVTEEIKEQEESVNEEVLEEVEETESIKEEIVEGGIATQEIIE 2725
Query: 1560 MSGQGSQ------LSTKKLA---------ISSDVAVDPKMFEKHASTDHLQEQISDTNEA 1426
+ + ++KL + +V+V ++ E+ ++T+ + E+ NE
Sbjct: 2726 EESDTKEVVEEEVIDSEKLVDAGSVTGEVMPEEVSVTDEVVEEGSTTEEVLEEQKSVNEE 2785
Query: 1425 AVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQ--ISDDENKSTGITAEENMLEK-GK 1255
V+D + +D + + + + + I I++ + +E ++ E+++EK G
Sbjct: 2786 VVEDGLTIDDFVGLQGSTTEEVVEEDGSAIEKILEEETATEEIVEKQVSVTEDIVEKEGS 2845
Query: 1254 LNSEIKTDRT--SEILAGRS-DEERDQVSQFSTEELLMCSGTVKDPNNFEKCSVSHRRQE 1084
+N EI + + EI+ G S EE + +TEE++ G + +
Sbjct: 2846 VNEEIIEEASVAEEIIQGGSFTEEIVGQEESATEEVIDEEGLISN--------------- 2890
Query: 1083 QIGHKNDNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCTTEVRIAGEL 904
+I + + +V E + + + + D E A +IV D + E EL
Sbjct: 2891 EIEEEEEKSVTEEM----IEEVEEVSVDDEVEEVSVAEEIVEEELVDDEILPE-----EL 2941
Query: 903 HEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVGTDVVTYQL 724
D+ E ++ T V E+S L EV A SE D K V D V ++
Sbjct: 2942 SATEDVIEEVRSVTD-----EIVQEESVCEEILEQEVSA--SEEYVDDKSVTDDFVGHE- 2993
Query: 723 QEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEENIVKKETAIDEKMQEK 544
+ V+ + N + E++ + S+ EE + K+ + +EK+QE+
Sbjct: 2994 --------RSVIQDVENTESVT---------EEIAEVDKSVIEEAVEKQGSVTEEKVQEE 3036
Query: 543 WQLKADAASE---IVARFVNEE-SGYARQLPTEKLAMSTDTVGDYKISE-------KDIV 397
+L + E + V +E SG E D + K + ++I
Sbjct: 3037 EELDTEEVLEDKSVTGDVVEQEGSGKDESEAKESFTEEVDELKSVKEEDQETEYISREIE 3096
Query: 396 SHLSQEQIHDKDEVVDETIHATDTVNKD---ETAATDDTLSEKEKENGNLKTECSVESTS 226
+ EQ +++ +++ + T+++ KD E + T + L E + N + E
Sbjct: 3097 EESATEQHSEQELSINKEVVETESLTKDIEEEKSTTQEILEETQSVNEEIVEE------- 3149
Query: 225 AIAAGYARQLSTEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDTVNK 46
+ T+E+ + I E+ + E+ DE+V T+ V +
Sbjct: 3150 --------ERDTDEVLKEKVSPSEEVIEEQASTTEEFVEERSSTDEIVEVEDLFTEEVKE 3201
Query: 45 DETAATDDTLSE 10
E + T++ + E
Sbjct: 3202 REGSVTEEIVEE 3213
Score = 102 bits (253), Expect = 2e-18
Identities = 241/1254 (19%), Positives = 527/1254 (42%), Gaps = 98/1254 (7%)
Frame = -3
Query: 3468 EKTGSVNQGVCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDN- 3292
EK SV + + S+T+ + ++ T V +S+ + +E+E + N + ++
Sbjct: 1478 EKEESVTEEIVRQEESTTE-KIVKDVSPTEDFVEQTDSVTEKVIEQEGS---NTEVAEDV 1533
Query: 3291 -KKCTAGSLLEKKD---NVEVVIPSVKVRKKR-DPASCSKTISSCKPRKASINKTNENLN 3127
+K +A E++D N +V V K+ D S ++ I S+ + +
Sbjct: 1534 EEKESASDEHEQEDVSVNAQVTYEKKSVTKEIVDEVSRTEEIVE---ENGSVTEGVDETG 1590
Query: 3126 MPSTQINKQELAGVIVLSDNS-DDAAVSKGKVKEANTVIKGATSSKKVKISSTGENSQER 2950
+ +I ++ V+ D S + V G V E V G+ + V+ S E +
Sbjct: 1591 SVTEEIIEEATVTEEVVEDGSVTEEVVEDGSVTE-EVVEDGSVIQEVVEDGSVTEEIVQE 1649
Query: 2949 NSFAND------AALNAKLQG----SDKMKNTDVATENCVLKDKEKVSHTSNISQEESSG 2800
N + ++N +++ S ++ T+ TE + + S I +EE S
Sbjct: 1650 NGSVTEEIVEEEGSVNEEVEEEVSVSGEVDETEYVTEEVEEEGSVEGSVVEEIVEEEGSV 1709
Query: 2799 A---------NDVAVNEKLKASDIEKGV---DTTVKDANHTKKGNVSIMVGPIKQQKNVA 2656
+ ND V + ++E+ V D ++DA+ + +++ +++
Sbjct: 1710 SEVVDETELVNDEIVEQAPFTEEVEEQVSVNDEIIEDAS---------VAEAVEESESIT 1760
Query: 2655 KGISMNEKMKGKGSVAKNATAINAATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAK 2476
+ +S E+ + KG V + A T E G + + E+++V I K +
Sbjct: 1761 ESVSQEEETE-KGFVIEKVEETGAVTE-EIVQDGLITEEILEESESVNGEIINKESDAEE 1818
Query: 2475 RSESKTCSSEKKN-IGNTLQALDEENKNVEVTIDRKIQGKGKRSESKTGSIP--VMVAGC 2305
E++ + E G+T + + EE +V ++ K + + + S+ ++ G
Sbjct: 1819 ILETEFLTEEVVGQAGSTSEEIVEEEGSVTKEVEEKESVTEELVDEGSVSVTEELVDEGS 1878
Query: 2304 VNKASCEKFNQSAKEF----TMSTDVLKDA----KVFEKD-VATHQL-EKGSGSNDVV-- 2161
V + E+ A+E + + ++++D +V EK+ AT ++ + GSG+ND V
Sbjct: 1879 VTEEVVEQGGSIAQEIVEEESATEEIIRDETNVEEVLEKEGSATEEIVQDGSGTNDFVGK 1938
Query: 2160 ----IDKNINAKVAV--EKVDTEIN-VAVFTEKGSISNTLH----ILEDINKKKEATNEE 2014
I++ + +++ EK+ E + + F E+ SI + + E++ ++E+ EE
Sbjct: 1939 QGSVIEEVVEEEISTTEEKLKEEASAIEEFVEEESIREDVLEESLVTENVVGQQESVTEE 1998
Query: 2013 KLPEKGELSAELKPDSDSRSEFVATCVNEVSGQVNNLSIEEFTMSRDRPEDAEIFKETVG 1834
+ +G + ++ + +S +E + V+ ++ + EE ++ +E +
Sbjct: 1999 IVDGEGSFTEDIVEEEESVTEEIVVDEESVTKEI--VEDEELVTEEIVEDEGSFTEEVIE 2056
Query: 1833 THQLEEKVGSTYAVPSGEKRDVNLILKEVVT--AANDSNLTEEKTISNTAHTADDVRKEM 1660
L E+V T V E+ V +KE++ + + + EEK+++ + V++E+
Sbjct: 2057 ERSLIEEVEDTETVAEKEEGSV---IKEIIDEKSLTEKIVEEEKSVTEEVEEKESVKEEV 2113
Query: 1659 E----VAIEERMQEKGVSYSEKKAGTKSDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDP 1492
E V EE +G+ E + T+ V E + L+T + ++
Sbjct: 2114 EEQRLVVEEEGSATEGIV--EDRLATEGIVDDILVTEEIVEDG-LATDEFVEQQGSIIEE 2170
Query: 1491 KMFEKHASTDHLQEQISDTNEAAVD--DKINPEDMMKKVDTAINDAIFTEKKIISNII-Q 1321
+ ++ + T+ + E+ NE V+ I +D ++ V I + TE+ I + +
Sbjct: 2171 VLDDEGSVTEEIVEEEGSPNEEIVEGVSVIEEDDNIEPVSEEIVEGSVTEEMIKEGLENE 2230
Query: 1320 ISDDENKSTGITAEENMLEKGKLNSEIKTDR---TSEILAGRSDEERDQVSQFS-TEELL 1153
+ DE+ T EE + ++G ++ EI + T EI+ D + + S +EE++
Sbjct: 2231 VILDEDSIT----EEALEKEGSVSEEIVEEMGSLTEEIVDEERSTSEDMIEEGSASEEII 2286
Query: 1152 MCSGTVKDPNNFEKCSVSHR--RQEQIGHKNDNAVIE-NLQAYAVNNCDTGAKDGNFTEK 982
V++ E+ SV ++++ K IE N + + + G+ ++
Sbjct: 2287 QEESQVEEV--VEEVSVIDEIVEEDELDTKEVVEEIEFNTEEVVEHKEEEGSVAEEIVQE 2344
Query: 981 ENASKIVSSLHEDIKCTTEVRIAG------ELHEKRDLKSEFKANTTLETVGGCVNEKSR 820
E + + E++ TE + E+ E+R + E + N +E V E+
Sbjct: 2345 EKEGSVNEEIIEEVGSITEEMVEQDVSDNEEIVEERSVIEEAEENVWIEKE---VEEEGL 2401
Query: 819 HVSQLSTEVLAMSSEMAEDAKVVGTDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPP 640
++ E ++S E AE+ + +++ +++E VN++ + +
Sbjct: 2402 DNEEVIDEEDSVS-EQAEEEVYINEEILKESSDVEDVKVENELMNEEVNEETQSVAENNE 2460
Query: 639 TGDEKVGNIAYSLYEENIVKKETAIDEKMQEKWQLKADAASEIVARFVNEESGYARQLPT 460
D+++ N Y + E V +E +DE K + ++ E + E+ L
Sbjct: 2461 E-DKELDN--YVVEETESVTEEVVVDEVPNSKEVQEIESIIEEIV----EDGLTTDDLVG 2513
Query: 459 EKLAMSTDTVGDYKISEKDIVSHLSQEQIHDKDEVVDETIHATDTVNKD---ETAATDDT 289
++ ++ + V + ++IV S + +K E V E I ++V D E + T++
Sbjct: 2514 QQGSVIEEVVEEVGSDSEEIVEEASITEEVEKKESVTEDILVEESVTGDILVEGSVTEEV 2573
Query: 288 LSEKE-------KENGNLKTECSVESTSAIAAGYARQLSTEELAMSTD------IEEDYK 148
+ E++ E G++ E E A + TEE+ ++E+
Sbjct: 2574 VGEEKLVSEEIVTEEGSVAQEIVEEDAPATEEIDEIESVTEEVVEEEGPVDEEIVQEEGS 2633
Query: 147 ISEKDI-----VSHLLQEQVHDKDEVVGETIHATDTVNKDETAATDDTLSEKEK 1
++E+ I V +++EQ + +E+ E + A+ + ++E+ ++ S E+
Sbjct: 2634 VTEEIIQGESKVEEVVEEQGSENEEIFVEEVSASQEIVQNESEVVEEEGSVTEE 2687
Score = 90.9 bits (224), Expect = 4e-15
Identities = 187/917 (20%), Positives = 371/917 (40%), Gaps = 77/917 (8%)
Frame = -3
Query: 2526 NKNVEVTIEGKIQGKAKRS----------ESKTCSSEKKNIGNTLQALDEENKNVEVTID 2377
N ++ T E + K+K S E S EKK + +Q L+ N+E D
Sbjct: 419 NSKIKPTYEENDEDKSKISIETSEIDRDKEPFRISEEKKVVKEDVQELE----NIEYEFD 474
Query: 2376 RKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAKEFTMSTDVLKDAKVFEKDVATH 2197
+ ++ I + + K S E +N +EF ++++ T
Sbjct: 475 ETFDFFDEDAKRNIDDIRKDIQSQIMK-SVENYNSEKEEF-------------KRNIETQ 520
Query: 2196 QLEKGSGSNDVVIDKNINAKVAVEKVDTEINVAVFTE----------------KGSISNT 2065
+E G G N N A++ TEI V K S+ +
Sbjct: 521 LIESGDGMNAG------NYSSALQDNSTEIPTMVLVPGVLTVFLLTIIWVLVYKHSLIDR 574
Query: 2064 LHILEDINKK---KEATNEEKLPEKGELSAELKPDSDSRSEFVATCVNEVSGQVNNLSIE 1894
+H K+ KE +EE EK + + + ++ E + N+ + Q + E
Sbjct: 575 VHGTGKTKKEEKMKELESEEFPKEKYNIEDMEETEKENEIEKIMD-ENKETEQTEEGNTE 633
Query: 1893 EFTMSRDRPEDAEIFKETVGTHQLEEKVGSTYAVPSGEKRDVNLILKEVVTAANDSNLTE 1714
EF ++ ++ + E + H EE+ T V E ++E+ N + E
Sbjct: 634 EFVQEKELNQET-LENEIIVDHIKEEE--DTRNVKEQESVLEESPIEELPVENNIGKINE 690
Query: 1713 E--KTISNTAHTADDVRKEM------EVAIEERMQEKGVSYSEKKAGTKSDT-----VGG 1573
E + I N + V KE+ E+ +EE ++ +S SE+ T+ DT V
Sbjct: 691 EVEEFILNEIPLEEQVPKELPQEEIEEIVVEELPIDEHLS-SEETTVTEEDTFKEENVSE 749
Query: 1572 RVDEMSGQGSQLSTKKLAISSDVAVDPKMFEK------------HASTDHLQEQISDTNE 1429
+ E + + ++ ++ VD K+++K + L EQIS +E
Sbjct: 750 EIPEGGIAIEDVPVDEETVTEEITVDEKIYDKLPNEIETVNEEMPVEDETLTEQISSEHE 809
Query: 1428 AAVDDKINPEDMMKKVDT-AINDAIFTEKKIISNIIQISDDENKSTGITAEENMLEKGKL 1252
++ I + + +T ++ D I E + +I +E T EE G+L
Sbjct: 810 RVPEEIIEEKPFTEGEETESLTDEIVEEGVVTDDI----PEEQIITEKVQEEEEFVTGEL 865
Query: 1251 NSEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKCSVSHRRQEQIGH 1072
+ E + E+ A + E D+ S TEE++ G V D + V+ +++I +
Sbjct: 866 SEEDIINEKDEVSASKEIVE-DEASV--TEEVVEEEGAVSD-----EVQVTESVEDEIIN 917
Query: 1071 KN--DNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIK-CTTEVRIAGELH 901
+ D ++E Q +V + + +D + E+ + V+ + E+ K E+ G +
Sbjct: 918 QGIVDEVIVE--QEASVTD-EIVKEDESVIEEIAVEETVTEVVEETKPMDEEIVDQGSVV 974
Query: 900 EKRDLKS--EFK-----ANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVGTD 742
E ++ + E K + LE G E + E++ S + + VG++
Sbjct: 975 ENEEVSTTEEVKDIGSVSEEVLEEEGFGTEEFVGQQGSVIEEIVETESSTEKVLEDVGSN 1034
Query: 741 VVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEENIVKKETAID 562
V ++ + G Q +V E V+ E + T +E V + S+ EE IV++ +A +
Sbjct: 1035 VE--EIVQEEGPVAQEIVHEEVSTTEKHDEVDRSTTEEIVEKVG-SVSEEIIVEEVSASE 1091
Query: 561 EKMQEKWQLKADAASEIVARFVNEESGYARQLPTEKLAMSTDTVG-----DYKISEKD-I 400
E ++E + E + V E ++ ++++ + + +G + +I EK+ I
Sbjct: 1092 EIVEEGSVTEEVVEEEKLINEVGETESVTEEIVQKEVSDAEEVLGQEGSMNEEILEKESI 1151
Query: 399 VSHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVESTSAI 220
V + + +E+VD A + K+E T++ + + +K E S+ AI
Sbjct: 1152 VEEIVGPEGSVTEEIVDHGSFAEEV--KEEELVTEEAVQYEGSVTEEIKEEESITENEAI 1209
Query: 219 AAGYARQL------STEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATD 58
++ +T+E+ ++ + ++E + +++E+ +++VGE T+
Sbjct: 1210 EESAFAEIIEEKGPNTDEIVKEEGLDTEEIVNEVSVTDEVIEEEKLVNEQIVGEERSVTE 1269
Query: 57 TVNKDETAATDDTLSEK 7
+ E +AT+D + E+
Sbjct: 1270 KPVEVERSATEDLVEEE 1286
Score = 77.8 bits (190), Expect = 3e-11
Identities = 224/1177 (19%), Positives = 467/1177 (39%), Gaps = 67/1177 (5%)
Frame = -3
Query: 3459 GSVNQGVCNLSSSSTKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNKKCT 3280
GSV Q + + +T+ E E T V E + + +++E +V ++ G++K
Sbjct: 2589 GSVAQEIVEEDAPATE-EIDEIESVTEEVVEEEGPVDEEIVQEEGSVTEEIIQGESK--- 2644
Query: 3279 AGSLLEKK--DNVEVVIPSVKVRKK---------RDPASCSKTISSCKPRKASINKTNEN 3133
++E++ +N E+ + V ++ + S ++ I K ++ S+N+
Sbjct: 2645 VEEVVEEQGSENEEIFVEEVSASQEIVQNESEVVEEEGSVTEEI---KEQEESVNEEVLE 2701
Query: 3132 LNMPSTQINKQELAGVI----VLSDNSDDAAVSKGKVKEANTVIKGATSSKKV---KISS 2974
+ I ++ + G I ++ + SD V + +V ++ ++ + + +V ++S
Sbjct: 2702 EVEETESIKEEIVEGGIATQEIIEEESDTKEVVEEEVIDSEKLVDAGSVTGEVMPEEVSV 2761
Query: 2973 TGENSQERNSFANDAALNAKLQGSDKMKNTDVATENCVLKDKEKV--SHTSNISQEESSG 2800
T E +E ++ ++ K N +V + + D + S T + +E+ S
Sbjct: 2762 TDEVVEEGST-------TEEVLEEQKSVNEEVVEDGLTIDDFVGLQGSTTEEVVEEDGSA 2814
Query: 2799 ANDVAVNEKLKASDIEKGVDTTVKDANHTKKGNVSI-MVGPIKQQKNVAKGISMNEKMKG 2623
+ E +EK V T K+G+V+ ++ + + +G S E++ G
Sbjct: 2815 IEKILEEETATEEIVEKQVSVTEDIVE--KEGSVNEEIIEEASVAEEIIQGGSFTEEIVG 2872
Query: 2622 KGSVAKNATAINAATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSSEK 2443
+ A E+ I N ++ E + VT E + E + E
Sbjct: 2873 QEESATEEVID------EEGLISNEIE----EEEEKSVTEE-----MIEEVEEVSVDDEV 2917
Query: 2442 KNIGNTLQALDEENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQSAK 2263
+ + + ++EE + E+ + + E ++ + ++ V + E+ +++
Sbjct: 2918 EEVSVAEEIVEEELVDDEILPEELSATEDVIEEVRSVTDEIVQEESVCEEILEQEVSASE 2977
Query: 2262 EFTMSTDVLKDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTEINVAVFTEK 2083
E+ V D E+ V DV +++ ++A +VD + ++
Sbjct: 2978 EYVDDKSVTDDFVGHERSVI----------QDVENTESVTEEIA--EVDKSVIEEAVEKQ 3025
Query: 2082 GSISNTLHILEDINKKKEATNEEKLPEKG------ELSAELKPDSDSRSEFVATC----- 1936
GS++ E + +++E EE L +K E K +S+++ F
Sbjct: 3026 GSVTE-----EKVQEEEELDTEEVLEDKSVTGDVVEQEGSGKDESEAKESFTEEVDELKS 3080
Query: 1935 VNEVSGQVNNLS--IEEFTMSRDRPE-DAEIFKETVGTHQLEEKVGSTYAVPSGEKRDVN 1765
V E + +S IEE + + E + I KE V T L + + EK
Sbjct: 3081 VKEEDQETEYISREIEEESATEQHSEQELSINKEVVETESLTKDI-------EEEKSTTQ 3133
Query: 1764 LILKEVVTAANDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAGTKSD 1585
IL+E + N+ + EE+ D+V KE VS SE+ ++
Sbjct: 3134 EILEE-TQSVNEEIVEEER-------DTDEVLKEK------------VSPSEEVIEEQAS 3173
Query: 1584 TVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDTNEAAVDDKIN 1405
T V+E S ST ++ D+ + + + T+ + E+ SDT E ++ +
Sbjct: 3174 TTEEFVEERS------STDEIVEVEDLFTEEVKEREGSVTEEIVEEGSDTGEIVEEEGSD 3227
Query: 1404 PEDMMKKVDTAINDAIFTEK-KIISNIIQISDDENKSTGITAEENMLEKGKLNSEIK--- 1237
E++++ + + N+ I E+ I I+Q G EE + ++G + EI
Sbjct: 3228 TEEILE--EGSFNEEIVEEEGSITEEILQ---------GSVTEEFVGQQGSVIEEIVETE 3276
Query: 1236 ---TDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKCSVSHRRQEQIGHKN 1066
+R E A +ER+ V++ EE+ V+ + E+ +N
Sbjct: 3277 SAIEERVEEESATEEVDERESVTEVVEEEVSSSDEVVE--GSIEEVI-----------EN 3323
Query: 1065 DNAVIENLQAYAVNNCD--TGAKDGNFTEKENASKIVSSLHEDIKCTTEVRIAGELHEKR 892
+ +V E + + V+ + G E E + + E+ + +E + E
Sbjct: 3324 EGSVTEEILEHEVSADENFVGQAVSVIEEVEGTESVTEEVVEETESVSEEIVEVSPTENV 3383
Query: 891 DLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVGTD-VVTYQLQEP 715
+++ +E G NE+ + +L + + +++ + +VVG D T ++E
Sbjct: 3384 VQQTDSVIEEVVEQKEGSFNEEI-DIRELGDDGVEEREKISTE-EVVGQDKSATGDVEES 3441
Query: 714 S--GDTNQV----------VVDEAVNKDEAA--------AKDCPPTGDEKVGNIAYSLYE 595
S GD +V +E V+ E ++ T D + G++A ++ E
Sbjct: 3442 SSTGDVEEVSSTEDEEEVSSTEEEVSSTEGLEEVSNTEDVEEVSSTEDVEEGSVAENVKE 3501
Query: 594 ENIVKKETAIDEKMQEKWQLKADAASEIVARFVNEESGYARQLPTEKLAMSTD-TVGDYK 418
+ +E +++E + K E++A + E ++P E+ M+ +V D
Sbjct: 3502 TKSITEEVSVEEDIITD---KVSVEQEVMAE-ASVEENILTEVPVEEEIMTEKLSVEDKA 3557
Query: 417 ISEKDIVSHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSV 238
++EK +S+E+I +D V E + A +V ++ + T +E + N+ E V
Sbjct: 3558 LNEK----IMSEEEIVIEDGNVHEVVPAEVSVTEEIPGVEETTNNESHVKGENVVNEVVV 3613
Query: 237 ESTSAIAAGYARQLSTEELAMSTDIE-EDYKISEKDI 130
+ S +E+ D E Y + KD+
Sbjct: 3614 DDNSV----------NDEIQFDDDSSIEIYTVDSKDV 3640
>ref|NP_725510.2| Stretchin-Mlck, isoform V [Drosophila melanogaster]
gi|440214444|gb|AAF58087.3| Stretchin-Mlck, isoform V
[Drosophila melanogaster]
Length = 7944
Score = 115 bits (287), Expect = 2e-22
Identities = 251/1157 (21%), Positives = 442/1157 (38%), Gaps = 70/1157 (6%)
Frame = -3
Query: 3264 EKKDNVEVVIPSVKVRKKRDPASCSKTISSCKPRKASINKTNENLNMPSTQINKQELAGV 3085
+++++ + I + + K+ S K+I K +T ++ S + E+
Sbjct: 3506 KREESQKEEIKDSEAKHKKSKVSEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSE 3565
Query: 3084 IVLSDNSDD----------AAVSKGKVKEANTVIKGATSSKKVKI--SSTGENSQ--ERN 2947
+ + + + A K KV E ++ + KK K S+ E SQ E +
Sbjct: 3566 KITDEKAQESQKKEVKGSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVS 3625
Query: 2946 SFANDAALNAKLQGSDKMKNTDV-------------ATENCVLKDKEKVSHTSNISQEES 2806
++ + K Q S K + D + E L+DK++ S I ++
Sbjct: 3626 EIVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQ 3685
Query: 2805 SGANDVAVNEKLKASDIEKGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEK-M 2629
V+EK+ ++ VKD+ K + I+++K K E +
Sbjct: 3686 KAEVSETVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAI 3745
Query: 2628 KGKGSVAKNATAINAATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSS 2449
K A+ + ++ EK + D E K KAK E K+
Sbjct: 3746 DEKSQKAEVSEIVSEKITDEKAQESQKKEVKDSEAK----------PKKAKVLEKKSIEE 3795
Query: 2448 EKKNIGNTLQALDEENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQS 2269
EK D++ + ID K Q K + SE + K + EK +S
Sbjct: 3796 EKLE--------DKKETQTDSAIDEKSQ-KAEVSEIVS-----------EKITDEKAQES 3835
Query: 2268 AKEFTMSTDVL-KDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTEINVAVF 2092
KE ++ K AKV EK + + EK + + I+ K +V ++ +
Sbjct: 3836 QKEEVKDSEAKPKKAKVLEK--KSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKIT 3893
Query: 2091 TEKGSISNTLHILEDINKKKEA-------TNEEKLPEKGELSAELKPDSDSRSEFVATCV 1933
EK S + K K+A EEKL +K E E D S+ V+ V
Sbjct: 3894 DEKAQESQKKEVKGSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIV 3953
Query: 1932 NE--VSGQVNNLSIEEFTMSRDRPEDAEIF-KETVGTHQLE---EKVGSTYAVPSGEKRD 1771
+E + +EE S +P+ A++ K+++ +LE EK + +K +
Sbjct: 3954 SEKITDEKAQESQMEEVKDSEAKPKKAKVLEKKSIEEEKLENKKEKQTESAIDEKSQKAE 4013
Query: 1770 VNLILKEVVT--AANDSNLTEEKTISNTAHTADDVRKEM--EVAIEERMQEKGVSYSEKK 1603
V+ I+ E +T A +S E K A + K+ E +E++ +++ S ++K
Sbjct: 4014 VSEIVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEK 4073
Query: 1602 A--GTKSDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDTNE 1429
+ S+ V + + Q SQ K D PK + +E++ D E
Sbjct: 4074 SQKAEVSEIVSENITDEKAQESQKKEVK-----DSEAKPKKAKVLEKKSIEEEKLEDKKE 4128
Query: 1428 AAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGI------TAEENML 1267
D I+ + +V +++ I EK S ++ D E K + EE L
Sbjct: 4129 TQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKL 4188
Query: 1266 EKGK-------LNSEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKC 1108
E K ++ + + SEI++ +E+ Q SQ +E+ K EK
Sbjct: 4189 EDKKEKQTESAIDEKSQKAEVSEIVSENITDEKAQESQ--KKEVKDSEAKPKKAKVLEKK 4246
Query: 1107 SVSHRRQEQIGHKNDNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCTT 928
S+ + E K + I+ ++K S+IVS K T
Sbjct: 4247 SIEEEKLEDKKEKQTESAIDEK-----------------SQKAEVSEIVSE-----KITE 4284
Query: 927 EVRIAGELHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVG 748
E + E +D K++ K LE E+++ + T+ + E ++ A+V
Sbjct: 4285 EKAQESQKKEVKDSKAKPKKAKVLEKKS---IEEAKLEDKKETQTDSAIDEKSQKAEV-- 4339
Query: 747 TDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEENIVKKETA 568
+++V+ ++ + +Q E V EA K EK L + + E+A
Sbjct: 4340 SEIVSEKITDEKAQESQ---KEEVKDSEAKPKKAKVL--EKKSIEEEKLENKKEKQTESA 4394
Query: 567 IDEKMQEKWQLKADAASEIVARFVNEESGYARQLPTEKLAMSTDTVGDYKISEKDIVSHL 388
IDEK Q KA+ SEIV+ + +E A++ +++ S K+ EK +
Sbjct: 4395 IDEKSQ-----KAE-VSEIVSEKITDEK--AQESQKKEVKGSEAKPKKAKVLEK---KSI 4443
Query: 387 SQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEK---EKENGNLKTECSVESTSAIA 217
+E++ DK E +T A D K + A + +SEK EK + K E
Sbjct: 4444 EEEKLEDKKE--KQTESAID--EKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKK 4499
Query: 216 AGYARQLSTEELAM------STDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDT 55
A + S EE + TD D K S+K VS ++ E++ D+ + D+
Sbjct: 4500 AKVLEKKSIEEAKLEDKKETQTDSAIDEK-SQKAEVSEIVSEKITDEKAQESQKEEVKDS 4558
Query: 54 VNKDETAATDDTLSEKE 4
K + A + S +E
Sbjct: 4559 EAKPKKAKVLEKKSIEE 4575
Score = 108 bits (271), Expect = 1e-20
Identities = 248/1198 (20%), Positives = 462/1198 (38%), Gaps = 72/1198 (6%)
Frame = -3
Query: 3420 STKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNK-KCTAGSLLEKKDNVE 3244
S KI +++ S V+ + + E I + D K K T ++ EK E
Sbjct: 4149 SEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAE 4208
Query: 3243 VV-IPSVKVRKKRDPASCSKTI--SSCKPRKASI----------------NKTNENLNMP 3121
V I S + ++ S K + S KP+KA + +T ++
Sbjct: 4209 VSEIVSENITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEK 4268
Query: 3120 STQINKQELAGVIVLSDNSDDAAV-----SKGKVKEANTVIKGATSSKKVKI-------S 2977
S + E+ + + + ++ SK K K+A + K + K++ S
Sbjct: 4269 SQKAEVSEIVSEKITEEKAQESQKKEVKDSKAKPKKAKVLEKKSIEEAKLEDKKETQTDS 4328
Query: 2976 STGENSQ--ERNSFANDAALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQEESS 2803
+ E SQ E + ++ + K Q S K + D + K EK S + +
Sbjct: 4329 AIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLENKKE 4388
Query: 2802 GANDVAVNEKLKASDIEKGVDTTVKD--ANHTKKGNVSIMVGPIKQQKNVAKGISMNEKM 2629
+ A++EK + +++ + V + D A ++K V K+ K + K EK+
Sbjct: 4389 KQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKGSEAKPKKAKVLEKKSIEEEKL 4448
Query: 2628 KGKGSVAKNATAINAATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSS 2449
+ K + +AI+ + +K + + + K E E +AK ++K
Sbjct: 4449 EDKKE-KQTESAIDEKS--QKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVL-- 4503
Query: 2448 EKKNIGNTLQALDEENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQS 2269
EKK+I + D++ + ID K Q K + SE + K + EK +S
Sbjct: 4504 EKKSIEEA-KLEDKKETQTDSAIDEKSQ-KAEVSEIVS-----------EKITDEKAQES 4550
Query: 2268 AKEFTMSTDVL-KDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTEINVAVF 2092
KE ++ K AKV EK + + K + D I+ K +V ++ +
Sbjct: 4551 QKEEVKDSEAKPKKAKVLEKK--SIEEAKLEDKKETQTDSAIDEKSQKAEVSEIVSEKIT 4608
Query: 2091 TEKGSISNTLHILEDINKKKEAT-------NEEKLPEKGELSAELKPDSDSRSEFVATCV 1933
EK S + + K K+A EEKL +K E E D S+ V+ V
Sbjct: 4609 DEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIV 4668
Query: 1932 NE--VSGQVNNLSIEEFTMSRDRPEDAEIF-KETVGTHQLEEKVGS---TYAVPSGEKRD 1771
+E + +EE S +P+ A++ K+++ +LE+K + + +K +
Sbjct: 4669 SEKITDEKAQESQMEEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAE 4728
Query: 1770 VNLILKEVVTAANDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAGTK 1591
V+ I+ E +T +E+ + A E + EE++++K +E K
Sbjct: 4729 VSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEK 4788
Query: 1590 S------DTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDTNE 1429
S + V ++ + Q SQ K++ S K+ EK + + E++ D E
Sbjct: 4789 SQKAEVSEIVSEKITDEKAQESQ--KKEVKGSEAKPKKAKVLEKKSIEE---EKLEDKKE 4843
Query: 1428 AAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGI------TAEENML 1267
+ I+ + +V +++ I EK S ++ D E K + EE L
Sbjct: 4844 KQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKL 4903
Query: 1266 EKGK-------LNSEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKC 1108
E K ++ + + SEI++ + +E+ Q SQ +E+ K EK
Sbjct: 4904 ENKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQ--KKEVKDSEAKPKKAKVLEKK 4961
Query: 1107 SVSHRRQEQIGHKN-DNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCT 931
S+ + E K ++A+ E Q V+ +EK K S E++K +
Sbjct: 4962 SIEEEKLEDKKEKQTESAIDEKFQKAEVSE--------TVSEKITDEKAEESRKEEVKDS 5013
Query: 930 TEVRIAGELHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVV 751
++ EK+ ++ E + + ++EKS+ EV SE D K
Sbjct: 5014 EAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQ-----KAEVSETVSEKITDEKAQ 5068
Query: 750 GTDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEENIVKKET 571
+ + E +++ +++ ++ K T + + E + + E
Sbjct: 5069 ESQKKEVKDSEAKPKKAKILEKKSIEIEKLDEKKEKQTETKVATDTKSQTVEVSEIVLEK 5128
Query: 570 AIDEKMQE--KWQLKADAASEIVARFVNEESGYARQLPTEKLAMSTDTVGDYKISEKDIV 397
+EK +E K +LK A A+ + ++S +L D G S+K
Sbjct: 5129 ISEEKAEESQKVELKDSEAKSKKAKVLEKKSTLKEKLDENDKKQKED--GATNKSQKAEA 5186
Query: 396 SHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVESTSAIA 217
+ + E+I ++ +T D+ K + D L EK +G +E A
Sbjct: 5187 ADVVPEKISEEKVAEIKTPEPMDSKAKSK----PDGLPADEKSHGAKVSESVPVKNEAEK 5242
Query: 216 AGYARQLSTEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDTVNKD 43
QLS ++ T ++ED + ++ L EQ D + +T + D+ KD
Sbjct: 5243 TD---QLSAKK---PTVLDEDLVVPKR---KPYLAEQT--ADSISLQTYKSMDSEYKD 5289
>ref|NP_001261019.1| Stretchin-Mlck, isoform U [Drosophila melanogaster]
gi|440214443|gb|AGB93551.1| Stretchin-Mlck, isoform U
[Drosophila melanogaster]
Length = 8255
Score = 115 bits (287), Expect = 2e-22
Identities = 251/1157 (21%), Positives = 442/1157 (38%), Gaps = 70/1157 (6%)
Frame = -3
Query: 3264 EKKDNVEVVIPSVKVRKKRDPASCSKTISSCKPRKASINKTNENLNMPSTQINKQELAGV 3085
+++++ + I + + K+ S K+I K +T ++ S + E+
Sbjct: 3506 KREESQKEEIKDSEAKHKKSKVSEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSE 3565
Query: 3084 IVLSDNSDD----------AAVSKGKVKEANTVIKGATSSKKVKI--SSTGENSQ--ERN 2947
+ + + + A K KV E ++ + KK K S+ E SQ E +
Sbjct: 3566 KITDEKAQESQKKEVKGSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVS 3625
Query: 2946 SFANDAALNAKLQGSDKMKNTDV-------------ATENCVLKDKEKVSHTSNISQEES 2806
++ + K Q S K + D + E L+DK++ S I ++
Sbjct: 3626 EIVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQ 3685
Query: 2805 SGANDVAVNEKLKASDIEKGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEK-M 2629
V+EK+ ++ VKD+ K + I+++K K E +
Sbjct: 3686 KAEVSETVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAI 3745
Query: 2628 KGKGSVAKNATAINAATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSS 2449
K A+ + ++ EK + D E K KAK E K+
Sbjct: 3746 DEKSQKAEVSEIVSEKITDEKAQESQKKEVKDSEAK----------PKKAKVLEKKSIEE 3795
Query: 2448 EKKNIGNTLQALDEENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQS 2269
EK D++ + ID K Q K + SE + K + EK +S
Sbjct: 3796 EKLE--------DKKETQTDSAIDEKSQ-KAEVSEIVS-----------EKITDEKAQES 3835
Query: 2268 AKEFTMSTDVL-KDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTEINVAVF 2092
KE ++ K AKV EK + + EK + + I+ K +V ++ +
Sbjct: 3836 QKEEVKDSEAKPKKAKVLEK--KSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKIT 3893
Query: 2091 TEKGSISNTLHILEDINKKKEA-------TNEEKLPEKGELSAELKPDSDSRSEFVATCV 1933
EK S + K K+A EEKL +K E E D S+ V+ V
Sbjct: 3894 DEKAQESQKKEVKGSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIV 3953
Query: 1932 NE--VSGQVNNLSIEEFTMSRDRPEDAEIF-KETVGTHQLE---EKVGSTYAVPSGEKRD 1771
+E + +EE S +P+ A++ K+++ +LE EK + +K +
Sbjct: 3954 SEKITDEKAQESQMEEVKDSEAKPKKAKVLEKKSIEEEKLENKKEKQTESAIDEKSQKAE 4013
Query: 1770 VNLILKEVVT--AANDSNLTEEKTISNTAHTADDVRKEM--EVAIEERMQEKGVSYSEKK 1603
V+ I+ E +T A +S E K A + K+ E +E++ +++ S ++K
Sbjct: 4014 VSEIVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEK 4073
Query: 1602 A--GTKSDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDTNE 1429
+ S+ V + + Q SQ K D PK + +E++ D E
Sbjct: 4074 SQKAEVSEIVSENITDEKAQESQKKEVK-----DSEAKPKKAKVLEKKSIEEEKLEDKKE 4128
Query: 1428 AAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGI------TAEENML 1267
D I+ + +V +++ I EK S ++ D E K + EE L
Sbjct: 4129 TQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKL 4188
Query: 1266 EKGK-------LNSEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKC 1108
E K ++ + + SEI++ +E+ Q SQ +E+ K EK
Sbjct: 4189 EDKKEKQTESAIDEKSQKAEVSEIVSENITDEKAQESQ--KKEVKDSEAKPKKAKVLEKK 4246
Query: 1107 SVSHRRQEQIGHKNDNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCTT 928
S+ + E K + I+ ++K S+IVS K T
Sbjct: 4247 SIEEEKLEDKKEKQTESAIDEK-----------------SQKAEVSEIVSE-----KITE 4284
Query: 927 EVRIAGELHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVG 748
E + E +D K++ K LE E+++ + T+ + E ++ A+V
Sbjct: 4285 EKAQESQKKEVKDSKAKPKKAKVLEKKS---IEEAKLEDKKETQTDSAIDEKSQKAEV-- 4339
Query: 747 TDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEENIVKKETA 568
+++V+ ++ + +Q E V EA K EK L + + E+A
Sbjct: 4340 SEIVSEKITDEKAQESQ---KEEVKDSEAKPKKAKVL--EKKSIEEEKLENKKEKQTESA 4394
Query: 567 IDEKMQEKWQLKADAASEIVARFVNEESGYARQLPTEKLAMSTDTVGDYKISEKDIVSHL 388
IDEK Q KA+ SEIV+ + +E A++ +++ S K+ EK +
Sbjct: 4395 IDEKSQ-----KAE-VSEIVSEKITDEK--AQESQKKEVKGSEAKPKKAKVLEK---KSI 4443
Query: 387 SQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEK---EKENGNLKTECSVESTSAIA 217
+E++ DK E +T A D K + A + +SEK EK + K E
Sbjct: 4444 EEEKLEDKKE--KQTESAID--EKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKK 4499
Query: 216 AGYARQLSTEELAM------STDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDT 55
A + S EE + TD D K S+K VS ++ E++ D+ + D+
Sbjct: 4500 AKVLEKKSIEEAKLEDKKETQTDSAIDEK-SQKAEVSEIVSEKITDEKAQESQKEEVKDS 4558
Query: 54 VNKDETAATDDTLSEKE 4
K + A + S +E
Sbjct: 4559 EAKPKKAKVLEKKSIEE 4575
Score = 108 bits (271), Expect = 1e-20
Identities = 248/1198 (20%), Positives = 462/1198 (38%), Gaps = 72/1198 (6%)
Frame = -3
Query: 3420 STKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNK-KCTAGSLLEKKDNVE 3244
S KI +++ S V+ + + E I + D K K T ++ EK E
Sbjct: 4149 SEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAE 4208
Query: 3243 VV-IPSVKVRKKRDPASCSKTI--SSCKPRKASI----------------NKTNENLNMP 3121
V I S + ++ S K + S KP+KA + +T ++
Sbjct: 4209 VSEIVSENITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEK 4268
Query: 3120 STQINKQELAGVIVLSDNSDDAAV-----SKGKVKEANTVIKGATSSKKVKI-------S 2977
S + E+ + + + ++ SK K K+A + K + K++ S
Sbjct: 4269 SQKAEVSEIVSEKITEEKAQESQKKEVKDSKAKPKKAKVLEKKSIEEAKLEDKKETQTDS 4328
Query: 2976 STGENSQ--ERNSFANDAALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQEESS 2803
+ E SQ E + ++ + K Q S K + D + K EK S + +
Sbjct: 4329 AIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLENKKE 4388
Query: 2802 GANDVAVNEKLKASDIEKGVDTTVKD--ANHTKKGNVSIMVGPIKQQKNVAKGISMNEKM 2629
+ A++EK + +++ + V + D A ++K V K+ K + K EK+
Sbjct: 4389 KQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKGSEAKPKKAKVLEKKSIEEEKL 4448
Query: 2628 KGKGSVAKNATAINAATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSS 2449
+ K + +AI+ + +K + + + K E E +AK ++K
Sbjct: 4449 EDKKE-KQTESAIDEKS--QKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVL-- 4503
Query: 2448 EKKNIGNTLQALDEENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQS 2269
EKK+I + D++ + ID K Q K + SE + K + EK +S
Sbjct: 4504 EKKSIEEA-KLEDKKETQTDSAIDEKSQ-KAEVSEIVS-----------EKITDEKAQES 4550
Query: 2268 AKEFTMSTDVL-KDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTEINVAVF 2092
KE ++ K AKV EK + + K + D I+ K +V ++ +
Sbjct: 4551 QKEEVKDSEAKPKKAKVLEKK--SIEEAKLEDKKETQTDSAIDEKSQKAEVSEIVSEKIT 4608
Query: 2091 TEKGSISNTLHILEDINKKKEAT-------NEEKLPEKGELSAELKPDSDSRSEFVATCV 1933
EK S + + K K+A EEKL +K E E D S+ V+ V
Sbjct: 4609 DEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIV 4668
Query: 1932 NE--VSGQVNNLSIEEFTMSRDRPEDAEIF-KETVGTHQLEEKVGS---TYAVPSGEKRD 1771
+E + +EE S +P+ A++ K+++ +LE+K + + +K +
Sbjct: 4669 SEKITDEKAQESQMEEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAE 4728
Query: 1770 VNLILKEVVTAANDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAGTK 1591
V+ I+ E +T +E+ + A E + EE++++K +E K
Sbjct: 4729 VSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEK 4788
Query: 1590 S------DTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDTNE 1429
S + V ++ + Q SQ K++ S K+ EK + + E++ D E
Sbjct: 4789 SQKAEVSEIVSEKITDEKAQESQ--KKEVKGSEAKPKKAKVLEKKSIEE---EKLEDKKE 4843
Query: 1428 AAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGI------TAEENML 1267
+ I+ + +V +++ I EK S ++ D E K + EE L
Sbjct: 4844 KQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKL 4903
Query: 1266 EKGK-------LNSEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKC 1108
E K ++ + + SEI++ + +E+ Q SQ +E+ K EK
Sbjct: 4904 ENKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQ--KKEVKDSEAKPKKAKVLEKK 4961
Query: 1107 SVSHRRQEQIGHKN-DNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCT 931
S+ + E K ++A+ E Q V+ +EK K S E++K +
Sbjct: 4962 SIEEEKLEDKKEKQTESAIDEKFQKAEVSE--------TVSEKITDEKAEESRKEEVKDS 5013
Query: 930 TEVRIAGELHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVV 751
++ EK+ ++ E + + ++EKS+ EV SE D K
Sbjct: 5014 EAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQ-----KAEVSETVSEKITDEKAQ 5068
Query: 750 GTDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEENIVKKET 571
+ + E +++ +++ ++ K T + + E + + E
Sbjct: 5069 ESQKKEVKDSEAKPKKAKILEKKSIEIEKLDEKKEKQTETKVATDTKSQTVEVSEIVLEK 5128
Query: 570 AIDEKMQE--KWQLKADAASEIVARFVNEESGYARQLPTEKLAMSTDTVGDYKISEKDIV 397
+EK +E K +LK A A+ + ++S +L D G S+K
Sbjct: 5129 ISEEKAEESQKVELKDSEAKSKKAKVLEKKSTLKEKLDENDKKQKED--GATNKSQKAEA 5186
Query: 396 SHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVESTSAIA 217
+ + E+I ++ +T D+ K + D L EK +G +E A
Sbjct: 5187 ADVVPEKISEEKVAEIKTPEPMDSKAKSK----PDGLPADEKSHGAKVSESVPVKNEAEK 5242
Query: 216 AGYARQLSTEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDTVNKD 43
QLS ++ T ++ED + ++ L EQ D + +T + D+ KD
Sbjct: 5243 TD---QLSAKK---PTVLDEDLVVPKR---KPYLAEQT--ADSISLQTYKSMDSEYKD 5289
>ref|NP_001188955.2| Stretchin-Mlck, isoform T [Drosophila melanogaster]
gi|440214442|gb|ADV37201.2| Stretchin-Mlck, isoform T
[Drosophila melanogaster]
Length = 7905
Score = 115 bits (287), Expect = 2e-22
Identities = 251/1157 (21%), Positives = 442/1157 (38%), Gaps = 70/1157 (6%)
Frame = -3
Query: 3264 EKKDNVEVVIPSVKVRKKRDPASCSKTISSCKPRKASINKTNENLNMPSTQINKQELAGV 3085
+++++ + I + + K+ S K+I K +T ++ S + E+
Sbjct: 3467 KREESQKEEIKDSEAKHKKSKVSEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSE 3526
Query: 3084 IVLSDNSDD----------AAVSKGKVKEANTVIKGATSSKKVKI--SSTGENSQ--ERN 2947
+ + + + A K KV E ++ + KK K S+ E SQ E +
Sbjct: 3527 KITDEKAQESQKKEVKGSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVS 3586
Query: 2946 SFANDAALNAKLQGSDKMKNTDV-------------ATENCVLKDKEKVSHTSNISQEES 2806
++ + K Q S K + D + E L+DK++ S I ++
Sbjct: 3587 EIVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQ 3646
Query: 2805 SGANDVAVNEKLKASDIEKGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEK-M 2629
V+EK+ ++ VKD+ K + I+++K K E +
Sbjct: 3647 KAEVSETVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAI 3706
Query: 2628 KGKGSVAKNATAINAATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSS 2449
K A+ + ++ EK + D E K KAK E K+
Sbjct: 3707 DEKSQKAEVSEIVSEKITDEKAQESQKKEVKDSEAK----------PKKAKVLEKKSIEE 3756
Query: 2448 EKKNIGNTLQALDEENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQS 2269
EK D++ + ID K Q K + SE + K + EK +S
Sbjct: 3757 EKLE--------DKKETQTDSAIDEKSQ-KAEVSEIVS-----------EKITDEKAQES 3796
Query: 2268 AKEFTMSTDVL-KDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTEINVAVF 2092
KE ++ K AKV EK + + EK + + I+ K +V ++ +
Sbjct: 3797 QKEEVKDSEAKPKKAKVLEK--KSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKIT 3854
Query: 2091 TEKGSISNTLHILEDINKKKEA-------TNEEKLPEKGELSAELKPDSDSRSEFVATCV 1933
EK S + K K+A EEKL +K E E D S+ V+ V
Sbjct: 3855 DEKAQESQKKEVKGSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIV 3914
Query: 1932 NE--VSGQVNNLSIEEFTMSRDRPEDAEIF-KETVGTHQLE---EKVGSTYAVPSGEKRD 1771
+E + +EE S +P+ A++ K+++ +LE EK + +K +
Sbjct: 3915 SEKITDEKAQESQMEEVKDSEAKPKKAKVLEKKSIEEEKLENKKEKQTESAIDEKSQKAE 3974
Query: 1770 VNLILKEVVT--AANDSNLTEEKTISNTAHTADDVRKEM--EVAIEERMQEKGVSYSEKK 1603
V+ I+ E +T A +S E K A + K+ E +E++ +++ S ++K
Sbjct: 3975 VSEIVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEK 4034
Query: 1602 A--GTKSDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDTNE 1429
+ S+ V + + Q SQ K D PK + +E++ D E
Sbjct: 4035 SQKAEVSEIVSENITDEKAQESQKKEVK-----DSEAKPKKAKVLEKKSIEEEKLEDKKE 4089
Query: 1428 AAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGI------TAEENML 1267
D I+ + +V +++ I EK S ++ D E K + EE L
Sbjct: 4090 TQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKL 4149
Query: 1266 EKGK-------LNSEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKC 1108
E K ++ + + SEI++ +E+ Q SQ +E+ K EK
Sbjct: 4150 EDKKEKQTESAIDEKSQKAEVSEIVSENITDEKAQESQ--KKEVKDSEAKPKKAKVLEKK 4207
Query: 1107 SVSHRRQEQIGHKNDNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCTT 928
S+ + E K + I+ ++K S+IVS K T
Sbjct: 4208 SIEEEKLEDKKEKQTESAIDEK-----------------SQKAEVSEIVSE-----KITE 4245
Query: 927 EVRIAGELHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVG 748
E + E +D K++ K LE E+++ + T+ + E ++ A+V
Sbjct: 4246 EKAQESQKKEVKDSKAKPKKAKVLEKKS---IEEAKLEDKKETQTDSAIDEKSQKAEV-- 4300
Query: 747 TDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEENIVKKETA 568
+++V+ ++ + +Q E V EA K EK L + + E+A
Sbjct: 4301 SEIVSEKITDEKAQESQ---KEEVKDSEAKPKKAKVL--EKKSIEEEKLENKKEKQTESA 4355
Query: 567 IDEKMQEKWQLKADAASEIVARFVNEESGYARQLPTEKLAMSTDTVGDYKISEKDIVSHL 388
IDEK Q KA+ SEIV+ + +E A++ +++ S K+ EK +
Sbjct: 4356 IDEKSQ-----KAE-VSEIVSEKITDEK--AQESQKKEVKGSEAKPKKAKVLEK---KSI 4404
Query: 387 SQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEK---EKENGNLKTECSVESTSAIA 217
+E++ DK E +T A D K + A + +SEK EK + K E
Sbjct: 4405 EEEKLEDKKE--KQTESAID--EKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKK 4460
Query: 216 AGYARQLSTEELAM------STDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDT 55
A + S EE + TD D K S+K VS ++ E++ D+ + D+
Sbjct: 4461 AKVLEKKSIEEAKLEDKKETQTDSAIDEK-SQKAEVSEIVSEKITDEKAQESQKEEVKDS 4519
Query: 54 VNKDETAATDDTLSEKE 4
K + A + S +E
Sbjct: 4520 EAKPKKAKVLEKKSIEE 4536
Score = 108 bits (271), Expect = 1e-20
Identities = 248/1198 (20%), Positives = 462/1198 (38%), Gaps = 72/1198 (6%)
Frame = -3
Query: 3420 STKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNK-KCTAGSLLEKKDNVE 3244
S KI +++ S V+ + + E I + D K K T ++ EK E
Sbjct: 4110 SEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAE 4169
Query: 3243 VV-IPSVKVRKKRDPASCSKTI--SSCKPRKASI----------------NKTNENLNMP 3121
V I S + ++ S K + S KP+KA + +T ++
Sbjct: 4170 VSEIVSENITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEK 4229
Query: 3120 STQINKQELAGVIVLSDNSDDAAV-----SKGKVKEANTVIKGATSSKKVKI-------S 2977
S + E+ + + + ++ SK K K+A + K + K++ S
Sbjct: 4230 SQKAEVSEIVSEKITEEKAQESQKKEVKDSKAKPKKAKVLEKKSIEEAKLEDKKETQTDS 4289
Query: 2976 STGENSQ--ERNSFANDAALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQEESS 2803
+ E SQ E + ++ + K Q S K + D + K EK S + +
Sbjct: 4290 AIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLENKKE 4349
Query: 2802 GANDVAVNEKLKASDIEKGVDTTVKD--ANHTKKGNVSIMVGPIKQQKNVAKGISMNEKM 2629
+ A++EK + +++ + V + D A ++K V K+ K + K EK+
Sbjct: 4350 KQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKGSEAKPKKAKVLEKKSIEEEKL 4409
Query: 2628 KGKGSVAKNATAINAATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSS 2449
+ K + +AI+ + +K + + + K E E +AK ++K
Sbjct: 4410 EDKKE-KQTESAIDEKS--QKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVL-- 4464
Query: 2448 EKKNIGNTLQALDEENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQS 2269
EKK+I + D++ + ID K Q K + SE + K + EK +S
Sbjct: 4465 EKKSIEEA-KLEDKKETQTDSAIDEKSQ-KAEVSEIVS-----------EKITDEKAQES 4511
Query: 2268 AKEFTMSTDVL-KDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTEINVAVF 2092
KE ++ K AKV EK + + K + D I+ K +V ++ +
Sbjct: 4512 QKEEVKDSEAKPKKAKVLEKK--SIEEAKLEDKKETQTDSAIDEKSQKAEVSEIVSEKIT 4569
Query: 2091 TEKGSISNTLHILEDINKKKEAT-------NEEKLPEKGELSAELKPDSDSRSEFVATCV 1933
EK S + + K K+A EEKL +K E E D S+ V+ V
Sbjct: 4570 DEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIV 4629
Query: 1932 NE--VSGQVNNLSIEEFTMSRDRPEDAEIF-KETVGTHQLEEKVGS---TYAVPSGEKRD 1771
+E + +EE S +P+ A++ K+++ +LE+K + + +K +
Sbjct: 4630 SEKITDEKAQESQMEEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAE 4689
Query: 1770 VNLILKEVVTAANDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAGTK 1591
V+ I+ E +T +E+ + A E + EE++++K +E K
Sbjct: 4690 VSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEK 4749
Query: 1590 S------DTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDTNE 1429
S + V ++ + Q SQ K++ S K+ EK + + E++ D E
Sbjct: 4750 SQKAEVSEIVSEKITDEKAQESQ--KKEVKGSEAKPKKAKVLEKKSIEE---EKLEDKKE 4804
Query: 1428 AAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGI------TAEENML 1267
+ I+ + +V +++ I EK S ++ D E K + EE L
Sbjct: 4805 KQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKL 4864
Query: 1266 EKGK-------LNSEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKC 1108
E K ++ + + SEI++ + +E+ Q SQ +E+ K EK
Sbjct: 4865 ENKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQ--KKEVKDSEAKPKKAKVLEKK 4922
Query: 1107 SVSHRRQEQIGHKN-DNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCT 931
S+ + E K ++A+ E Q V+ +EK K S E++K +
Sbjct: 4923 SIEEEKLEDKKEKQTESAIDEKFQKAEVSE--------TVSEKITDEKAEESRKEEVKDS 4974
Query: 930 TEVRIAGELHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVV 751
++ EK+ ++ E + + ++EKS+ EV SE D K
Sbjct: 4975 EAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQ-----KAEVSETVSEKITDEKAQ 5029
Query: 750 GTDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEENIVKKET 571
+ + E +++ +++ ++ K T + + E + + E
Sbjct: 5030 ESQKKEVKDSEAKPKKAKILEKKSIEIEKLDEKKEKQTETKVATDTKSQTVEVSEIVLEK 5089
Query: 570 AIDEKMQE--KWQLKADAASEIVARFVNEESGYARQLPTEKLAMSTDTVGDYKISEKDIV 397
+EK +E K +LK A A+ + ++S +L D G S+K
Sbjct: 5090 ISEEKAEESQKVELKDSEAKSKKAKVLEKKSTLKEKLDENDKKQKED--GATNKSQKAEA 5147
Query: 396 SHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVESTSAIA 217
+ + E+I ++ +T D+ K + D L EK +G +E A
Sbjct: 5148 ADVVPEKISEEKVAEIKTPEPMDSKAKSK----PDGLPADEKSHGAKVSESVPVKNEAEK 5203
Query: 216 AGYARQLSTEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDTVNKD 43
QLS ++ T ++ED + ++ L EQ D + +T + D+ KD
Sbjct: 5204 TD---QLSAKK---PTVLDEDLVVPKR---KPYLAEQT--ADSISLQTYKSMDSEYKD 5250
>ref|NP_001261018.1| Stretchin-Mlck, isoform S [Drosophila melanogaster]
gi|440214441|gb|AGB93550.1| Stretchin-Mlck, isoform S
[Drosophila melanogaster]
Length = 8216
Score = 115 bits (287), Expect = 2e-22
Identities = 251/1157 (21%), Positives = 442/1157 (38%), Gaps = 70/1157 (6%)
Frame = -3
Query: 3264 EKKDNVEVVIPSVKVRKKRDPASCSKTISSCKPRKASINKTNENLNMPSTQINKQELAGV 3085
+++++ + I + + K+ S K+I K +T ++ S + E+
Sbjct: 3467 KREESQKEEIKDSEAKHKKSKVSEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSE 3526
Query: 3084 IVLSDNSDD----------AAVSKGKVKEANTVIKGATSSKKVKI--SSTGENSQ--ERN 2947
+ + + + A K KV E ++ + KK K S+ E SQ E +
Sbjct: 3527 KITDEKAQESQKKEVKGSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVS 3586
Query: 2946 SFANDAALNAKLQGSDKMKNTDV-------------ATENCVLKDKEKVSHTSNISQEES 2806
++ + K Q S K + D + E L+DK++ S I ++
Sbjct: 3587 EIVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQ 3646
Query: 2805 SGANDVAVNEKLKASDIEKGVDTTVKDANHTKKGNVSIMVGPIKQQKNVAKGISMNEK-M 2629
V+EK+ ++ VKD+ K + I+++K K E +
Sbjct: 3647 KAEVSETVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAI 3706
Query: 2628 KGKGSVAKNATAINAATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSS 2449
K A+ + ++ EK + D E K KAK E K+
Sbjct: 3707 DEKSQKAEVSEIVSEKITDEKAQESQKKEVKDSEAK----------PKKAKVLEKKSIEE 3756
Query: 2448 EKKNIGNTLQALDEENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQS 2269
EK D++ + ID K Q K + SE + K + EK +S
Sbjct: 3757 EKLE--------DKKETQTDSAIDEKSQ-KAEVSEIVS-----------EKITDEKAQES 3796
Query: 2268 AKEFTMSTDVL-KDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTEINVAVF 2092
KE ++ K AKV EK + + EK + + I+ K +V ++ +
Sbjct: 3797 QKEEVKDSEAKPKKAKVLEK--KSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKIT 3854
Query: 2091 TEKGSISNTLHILEDINKKKEA-------TNEEKLPEKGELSAELKPDSDSRSEFVATCV 1933
EK S + K K+A EEKL +K E E D S+ V+ V
Sbjct: 3855 DEKAQESQKKEVKGSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIV 3914
Query: 1932 NE--VSGQVNNLSIEEFTMSRDRPEDAEIF-KETVGTHQLE---EKVGSTYAVPSGEKRD 1771
+E + +EE S +P+ A++ K+++ +LE EK + +K +
Sbjct: 3915 SEKITDEKAQESQMEEVKDSEAKPKKAKVLEKKSIEEEKLENKKEKQTESAIDEKSQKAE 3974
Query: 1770 VNLILKEVVT--AANDSNLTEEKTISNTAHTADDVRKEM--EVAIEERMQEKGVSYSEKK 1603
V+ I+ E +T A +S E K A + K+ E +E++ +++ S ++K
Sbjct: 3975 VSEIVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEK 4034
Query: 1602 A--GTKSDTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDTNE 1429
+ S+ V + + Q SQ K D PK + +E++ D E
Sbjct: 4035 SQKAEVSEIVSENITDEKAQESQKKEVK-----DSEAKPKKAKVLEKKSIEEEKLEDKKE 4089
Query: 1428 AAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGI------TAEENML 1267
D I+ + +V +++ I EK S ++ D E K + EE L
Sbjct: 4090 TQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKL 4149
Query: 1266 EKGK-------LNSEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKC 1108
E K ++ + + SEI++ +E+ Q SQ +E+ K EK
Sbjct: 4150 EDKKEKQTESAIDEKSQKAEVSEIVSENITDEKAQESQ--KKEVKDSEAKPKKAKVLEKK 4207
Query: 1107 SVSHRRQEQIGHKNDNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCTT 928
S+ + E K + I+ ++K S+IVS K T
Sbjct: 4208 SIEEEKLEDKKEKQTESAIDEK-----------------SQKAEVSEIVSE-----KITE 4245
Query: 927 EVRIAGELHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVVG 748
E + E +D K++ K LE E+++ + T+ + E ++ A+V
Sbjct: 4246 EKAQESQKKEVKDSKAKPKKAKVLEKKS---IEEAKLEDKKETQTDSAIDEKSQKAEV-- 4300
Query: 747 TDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEENIVKKETA 568
+++V+ ++ + +Q E V EA K EK L + + E+A
Sbjct: 4301 SEIVSEKITDEKAQESQ---KEEVKDSEAKPKKAKVL--EKKSIEEEKLENKKEKQTESA 4355
Query: 567 IDEKMQEKWQLKADAASEIVARFVNEESGYARQLPTEKLAMSTDTVGDYKISEKDIVSHL 388
IDEK Q KA+ SEIV+ + +E A++ +++ S K+ EK +
Sbjct: 4356 IDEKSQ-----KAE-VSEIVSEKITDEK--AQESQKKEVKGSEAKPKKAKVLEK---KSI 4404
Query: 387 SQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEK---EKENGNLKTECSVESTSAIA 217
+E++ DK E +T A D K + A + +SEK EK + K E
Sbjct: 4405 EEEKLEDKKE--KQTESAID--EKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKK 4460
Query: 216 AGYARQLSTEELAM------STDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDT 55
A + S EE + TD D K S+K VS ++ E++ D+ + D+
Sbjct: 4461 AKVLEKKSIEEAKLEDKKETQTDSAIDEK-SQKAEVSEIVSEKITDEKAQESQKEEVKDS 4519
Query: 54 VNKDETAATDDTLSEKE 4
K + A + S +E
Sbjct: 4520 EAKPKKAKVLEKKSIEE 4536
Score = 108 bits (271), Expect = 1e-20
Identities = 248/1198 (20%), Positives = 462/1198 (38%), Gaps = 72/1198 (6%)
Frame = -3
Query: 3420 STKIENQENAGSTVTAVRSENSMVTQGLEKESNVIVNVVIGDNK-KCTAGSLLEKKDNVE 3244
S KI +++ S V+ + + E I + D K K T ++ EK E
Sbjct: 4110 SEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAE 4169
Query: 3243 VV-IPSVKVRKKRDPASCSKTI--SSCKPRKASI----------------NKTNENLNMP 3121
V I S + ++ S K + S KP+KA + +T ++
Sbjct: 4170 VSEIVSENITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEK 4229
Query: 3120 STQINKQELAGVIVLSDNSDDAAV-----SKGKVKEANTVIKGATSSKKVKI-------S 2977
S + E+ + + + ++ SK K K+A + K + K++ S
Sbjct: 4230 SQKAEVSEIVSEKITEEKAQESQKKEVKDSKAKPKKAKVLEKKSIEEAKLEDKKETQTDS 4289
Query: 2976 STGENSQ--ERNSFANDAALNAKLQGSDKMKNTDVATENCVLKDKEKVSHTSNISQEESS 2803
+ E SQ E + ++ + K Q S K + D + K EK S + +
Sbjct: 4290 AIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLENKKE 4349
Query: 2802 GANDVAVNEKLKASDIEKGVDTTVKD--ANHTKKGNVSIMVGPIKQQKNVAKGISMNEKM 2629
+ A++EK + +++ + V + D A ++K V K+ K + K EK+
Sbjct: 4350 KQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKGSEAKPKKAKVLEKKSIEEEKL 4409
Query: 2628 KGKGSVAKNATAINAATHLEKKNIGNTLQALDVENKNVEVTIEGKIQGKAKRSESKTCSS 2449
+ K + +AI+ + +K + + + K E E +AK ++K
Sbjct: 4410 EDKKE-KQTESAIDEKS--QKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVL-- 4464
Query: 2448 EKKNIGNTLQALDEENKNVEVTIDRKIQGKGKRSESKTGSIPVMVAGCVNKASCEKFNQS 2269
EKK+I + D++ + ID K Q K + SE + K + EK +S
Sbjct: 4465 EKKSIEEA-KLEDKKETQTDSAIDEKSQ-KAEVSEIVS-----------EKITDEKAQES 4511
Query: 2268 AKEFTMSTDVL-KDAKVFEKDVATHQLEKGSGSNDVVIDKNINAKVAVEKVDTEINVAVF 2092
KE ++ K AKV EK + + K + D I+ K +V ++ +
Sbjct: 4512 QKEEVKDSEAKPKKAKVLEKK--SIEEAKLEDKKETQTDSAIDEKSQKAEVSEIVSEKIT 4569
Query: 2091 TEKGSISNTLHILEDINKKKEAT-------NEEKLPEKGELSAELKPDSDSRSEFVATCV 1933
EK S + + K K+A EEKL +K E E D S+ V+ V
Sbjct: 4570 DEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIV 4629
Query: 1932 NE--VSGQVNNLSIEEFTMSRDRPEDAEIF-KETVGTHQLEEKVGS---TYAVPSGEKRD 1771
+E + +EE S +P+ A++ K+++ +LE+K + + +K +
Sbjct: 4630 SEKITDEKAQESQMEEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAE 4689
Query: 1770 VNLILKEVVTAANDSNLTEEKTISNTAHTADDVRKEMEVAIEERMQEKGVSYSEKKAGTK 1591
V+ I+ E +T +E+ + A E + EE++++K +E K
Sbjct: 4690 VSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEK 4749
Query: 1590 S------DTVGGRVDEMSGQGSQLSTKKLAISSDVAVDPKMFEKHASTDHLQEQISDTNE 1429
S + V ++ + Q SQ K++ S K+ EK + + E++ D E
Sbjct: 4750 SQKAEVSEIVSEKITDEKAQESQ--KKEVKGSEAKPKKAKVLEKKSIEE---EKLEDKKE 4804
Query: 1428 AAVDDKINPEDMMKKVDTAINDAIFTEKKIISNIIQISDDENKSTGI------TAEENML 1267
+ I+ + +V +++ I EK S ++ D E K + EE L
Sbjct: 4805 KQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKL 4864
Query: 1266 EKGK-------LNSEIKTDRTSEILAGRSDEERDQVSQFSTEELLMCSGTVKDPNNFEKC 1108
E K ++ + + SEI++ + +E+ Q SQ +E+ K EK
Sbjct: 4865 ENKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQ--KKEVKDSEAKPKKAKVLEKK 4922
Query: 1107 SVSHRRQEQIGHKN-DNAVIENLQAYAVNNCDTGAKDGNFTEKENASKIVSSLHEDIKCT 931
S+ + E K ++A+ E Q V+ +EK K S E++K +
Sbjct: 4923 SIEEEKLEDKKEKQTESAIDEKFQKAEVSE--------TVSEKITDEKAEESRKEEVKDS 4974
Query: 930 TEVRIAGELHEKRDLKSEFKANTTLETVGGCVNEKSRHVSQLSTEVLAMSSEMAEDAKVV 751
++ EK+ ++ E + + ++EKS+ EV SE D K
Sbjct: 4975 EAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQ-----KAEVSETVSEKITDEKAQ 5029
Query: 750 GTDVVTYQLQEPSGDTNQVVVDEAVNKDEAAAKDCPPTGDEKVGNIAYSLYEENIVKKET 571
+ + E +++ +++ ++ K T + + E + + E
Sbjct: 5030 ESQKKEVKDSEAKPKKAKILEKKSIEIEKLDEKKEKQTETKVATDTKSQTVEVSEIVLEK 5089
Query: 570 AIDEKMQE--KWQLKADAASEIVARFVNEESGYARQLPTEKLAMSTDTVGDYKISEKDIV 397
+EK +E K +LK A A+ + ++S +L D G S+K
Sbjct: 5090 ISEEKAEESQKVELKDSEAKSKKAKVLEKKSTLKEKLDENDKKQKED--GATNKSQKAEA 5147
Query: 396 SHLSQEQIHDKDEVVDETIHATDTVNKDETAATDDTLSEKEKENGNLKTECSVESTSAIA 217
+ + E+I ++ +T D+ K + D L EK +G +E A
Sbjct: 5148 ADVVPEKISEEKVAEIKTPEPMDSKAKSK----PDGLPADEKSHGAKVSESVPVKNEAEK 5203
Query: 216 AGYARQLSTEELAMSTDIEEDYKISEKDIVSHLLQEQVHDKDEVVGETIHATDTVNKD 43
QLS ++ T ++ED + ++ L EQ D + +T + D+ KD
Sbjct: 5204 TD---QLSAKK---PTVLDEDLVVPKR---KPYLAEQT--ADSISLQTYKSMDSEYKD 5250