BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Cornus23_contig00013679
         (1517 letters)

Database: ./nr 
           77,306,371 sequences; 28,104,191,420 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

emb|CBI23326.3| unnamed protein product [Vitis vinifera]              602   e-169
ref|XP_002270943.2| PREDICTED: sphingosine kinase 1 isoform X1 [...   602   e-169
ref|XP_008224941.1| PREDICTED: sphingosine kinase 1-like isoform...   593   e-166
ref|XP_007211993.1| hypothetical protein PRUPE_ppa004781mg [Prun...   593   e-166
ref|XP_012091503.1| PREDICTED: sphingosine kinase 1 isoform X1 [...   581   e-163
ref|XP_006449226.1| hypothetical protein CICLE_v10015071mg [Citr...   581   e-163
gb|KDO75739.1| hypothetical protein CISIN_1g011290mg [Citrus sin...   581   e-163
ref|XP_006467889.1| PREDICTED: sphingosine kinase 1-like [Citrus...   581   e-163
ref|XP_010092628.1| Sphingosine kinase 1 [Morus notabilis] gi|58...   575   e-161
gb|KDO75738.1| hypothetical protein CISIN_1g011290mg [Citrus sin...   575   e-161
ref|XP_009376260.1| PREDICTED: sphingosine kinase 1 isoform X1 [...   572   e-160
ref|XP_008364137.1| PREDICTED: sphingosine kinase 1-like isoform...   567   e-159
ref|XP_007025779.1| Sphingosine kinase 1 isoform 2 [Theobroma ca...   566   e-158
ref|XP_007025778.1| Sphingosine kinase 1 isoform 1 [Theobroma ca...   566   e-158
ref|XP_002524674.1| Sphingosine kinase, putative [Ricinus commun...   565   e-158
ref|XP_004485708.1| PREDICTED: sphingosine kinase 1 isoform X1 [...   564   e-158
ref|XP_004293517.1| PREDICTED: sphingosine kinase 1-like isoform...   561   e-157
ref|XP_014506993.1| PREDICTED: sphingosine kinase 1-like [Vigna ...   559   e-156
ref|XP_013462482.1| D-erythro-sphingosine kinase/diacylglycerol ...   559   e-156
ref|XP_002317243.1| diacylglycerol kinase family protein [Populu...   558   e-156

>emb|CBI23326.3| unnamed protein product [Vitis vinifera]
          Length = 506

 Score =  602 bits (1553), Expect = e-169
 Identities = 303/454 (66%), Positives = 348/454 (76%), Gaps = 41/454 (9%)
 Frame = -2

Query: 1516 VEKEVLGFSIEGSRIKIKVVVEGGDEICCVGSGGALMRKSFVFEPSSEDSLRLWCQKLQE 1337
            VEKEVLGF+ EGSRI+I+ +VE G  +CCVGS G L+RK FVFE +S DS RLWCQKL+E
Sbjct: 61   VEKEVLGFASEGSRIRIRAIVENGGGLCCVGSRGKLVRKDFVFEIASADSHRLWCQKLRE 120

Query: 1336 FIDSLDRPKKLLILMNPYGGKKFASKIFLDDVKPLLEDANVEFTLQXXXXXXXXXXXXXL 1157
            +IDSL RPK+L + +NP+GGKK ASKIFLD V PLL+DA+++ T+Q             L
Sbjct: 121  YIDSLGRPKRLFVFVNPFGGKKSASKIFLDVVSPLLKDADIQLTIQETKHQ--------L 172

Query: 1156 HAKEIAKTLDISKYDGIVCVSGDGILVEVVNGLLEREDWESAIRMPLGVVPAGTGNGMAK 977
            HAK + +TLD+SKYDG++CVSGDGILVEVVNGLLER+DW+SAI+MP+GV+PAGTGNGMAK
Sbjct: 173  HAKAVTQTLDLSKYDGLICVSGDGILVEVVNGLLERDDWDSAIKMPIGVIPAGTGNGMAK 232

Query: 976  SLLDSVGNPCTASNATLAIIRGHKCSLDVSTILQGETRFFSVLMLAWGLVADIDIESEKY 797
            SLLDSVG+PC+  NA LAIIRGHKCSLDV+TILQGET+FFSVLMLAWGLVADIDIESEKY
Sbjct: 233  SLLDSVGDPCSPINAVLAIIRGHKCSLDVATILQGETKFFSVLMLAWGLVADIDIESEKY 292

Query: 796  RWMGSARLDFYALQRIFRLRKYDGRISFVPAPGFEAYGEPSYQNGESRGEVNICNPSQGE 617
            RWMGSARLDFYALQRI  LRKY+G ISFVPAPGFEA+GEPS   GES   +N  NPSQ E
Sbjct: 293  RWMGSARLDFYALQRILHLRKYNGCISFVPAPGFEAFGEPSTYKGESTSGLNTFNPSQEE 352

Query: 616  NIDPQKGGYCGPKVDVESLSWRKLDGPFVSIWLHNVPWGAEDTMAAPDA----------- 470
             I  Q+ GY GP +++E L WR +DGPFVSIWLHNVPWG EDT+AAPDA           
Sbjct: 353  PIKVQQHGYQGPNIELEKLQWRTIDGPFVSIWLHNVPWGGEDTLAAPDAKFSDGYLDLII 412

Query: 469  ------------------------------KVKAVVLEPGPRTEDPTKEGIIDADGEVLA 380
                                          KVKA VLEPGP TEDPTK GIID+DGEVLA
Sbjct: 413  IRDCPKLPLLALMSELNKGNHIKSPYVMYFKVKAFVLEPGPCTEDPTKGGIIDSDGEVLA 472

Query: 379  RGKGTFKCDQKALMAYDKLQITVDQGLVTLFTPI 278
            RG GT+KCDQKALMAYD LQI VDQGL T+F+PI
Sbjct: 473  RGNGTYKCDQKALMAYDNLQIAVDQGLATVFSPI 506


>ref|XP_002270943.2| PREDICTED: sphingosine kinase 1 isoform X1 [Vitis vinifera]
          Length = 489

 Score =  602 bits (1553), Expect = e-169
 Identities = 303/454 (66%), Positives = 348/454 (76%), Gaps = 41/454 (9%)
 Frame = -2

Query: 1516 VEKEVLGFSIEGSRIKIKVVVEGGDEICCVGSGGALMRKSFVFEPSSEDSLRLWCQKLQE 1337
            VEKEVLGF+ EGSRI+I+ +VE G  +CCVGS G L+RK FVFE +S DS RLWCQKL+E
Sbjct: 44   VEKEVLGFASEGSRIRIRAIVENGGGLCCVGSRGKLVRKDFVFEIASADSHRLWCQKLRE 103

Query: 1336 FIDSLDRPKKLLILMNPYGGKKFASKIFLDDVKPLLEDANVEFTLQXXXXXXXXXXXXXL 1157
            +IDSL RPK+L + +NP+GGKK ASKIFLD V PLL+DA+++ T+Q             L
Sbjct: 104  YIDSLGRPKRLFVFVNPFGGKKSASKIFLDVVSPLLKDADIQLTIQETKHQ--------L 155

Query: 1156 HAKEIAKTLDISKYDGIVCVSGDGILVEVVNGLLEREDWESAIRMPLGVVPAGTGNGMAK 977
            HAK + +TLD+SKYDG++CVSGDGILVEVVNGLLER+DW+SAI+MP+GV+PAGTGNGMAK
Sbjct: 156  HAKAVTQTLDLSKYDGLICVSGDGILVEVVNGLLERDDWDSAIKMPIGVIPAGTGNGMAK 215

Query: 976  SLLDSVGNPCTASNATLAIIRGHKCSLDVSTILQGETRFFSVLMLAWGLVADIDIESEKY 797
            SLLDSVG+PC+  NA LAIIRGHKCSLDV+TILQGET+FFSVLMLAWGLVADIDIESEKY
Sbjct: 216  SLLDSVGDPCSPINAVLAIIRGHKCSLDVATILQGETKFFSVLMLAWGLVADIDIESEKY 275

Query: 796  RWMGSARLDFYALQRIFRLRKYDGRISFVPAPGFEAYGEPSYQNGESRGEVNICNPSQGE 617
            RWMGSARLDFYALQRI  LRKY+G ISFVPAPGFEA+GEPS   GES   +N  NPSQ E
Sbjct: 276  RWMGSARLDFYALQRILHLRKYNGCISFVPAPGFEAFGEPSTYKGESTSGLNTFNPSQEE 335

Query: 616  NIDPQKGGYCGPKVDVESLSWRKLDGPFVSIWLHNVPWGAEDTMAAPDA----------- 470
             I  Q+ GY GP +++E L WR +DGPFVSIWLHNVPWG EDT+AAPDA           
Sbjct: 336  PIKVQQHGYQGPNIELEKLQWRTIDGPFVSIWLHNVPWGGEDTLAAPDAKFSDGYLDLII 395

Query: 469  ------------------------------KVKAVVLEPGPRTEDPTKEGIIDADGEVLA 380
                                          KVKA VLEPGP TEDPTK GIID+DGEVLA
Sbjct: 396  IRDCPKLPLLALMSELNKGNHIKSPYVMYFKVKAFVLEPGPCTEDPTKGGIIDSDGEVLA 455

Query: 379  RGKGTFKCDQKALMAYDKLQITVDQGLVTLFTPI 278
            RG GT+KCDQKALMAYD LQI VDQGL T+F+PI
Sbjct: 456  RGNGTYKCDQKALMAYDNLQIAVDQGLATVFSPI 489


>ref|XP_008224941.1| PREDICTED: sphingosine kinase 1-like isoform X1 [Prunus mume]
          Length = 493

 Score =  593 bits (1528), Expect = e-166
 Identities = 300/456 (65%), Positives = 351/456 (76%), Gaps = 43/456 (9%)
 Frame = -2

Query: 1516 VEKEVLGFSIEGSRIKIKVVVEGGDEICCVGSGGALMRKSFVFEPSSEDSLRLWCQKLQE 1337
            VEKEVLGF+ EG +I+I+ +VE GD ICCV S GA++RK FVF+P SEDS RLWCQKL+E
Sbjct: 46   VEKEVLGFAAEGPKIRIRALVEDGDGICCVASRGAVVRKEFVFKPLSEDSHRLWCQKLRE 105

Query: 1336 FIDSLDRPKKLLILMNPYGGKKFASKIFLDDVKPLLEDANVEFTLQXXXXXXXXXXXXXL 1157
             IDSL RPK+L + +NP+GG K ASKI+ + VKPL +DAN++FTLQ             L
Sbjct: 106  HIDSLGRPKRLFVFVNPFGGSKSASKIYAEHVKPLFQDANIQFTLQETQYQ--------L 157

Query: 1156 HAKEIAKTLDISKYDGIVCVSGDGILVEVVNGLLEREDWESAIRMPLGVVPAGTGNGMAK 977
            HAKE+AKTLD+SKYDGIVCVSGDGILVEVVNGLLEREDWE+AI+MPLGVVPAGTGNGMAK
Sbjct: 158  HAKEVAKTLDLSKYDGIVCVSGDGILVEVVNGLLEREDWEAAIKMPLGVVPAGTGNGMAK 217

Query: 976  SLLDSVGNPCTASNATLAIIRGHKCSLDVSTILQGETRFFSVLMLAWGLVADIDIESEKY 797
            SLLDSVG PCTASNA LAIIRG+K SLDV+TI QG+T+FFSVLMLAWGLVAD+DIESEKY
Sbjct: 218  SLLDSVGEPCTASNAILAIIRGNKRSLDVATIWQGKTKFFSVLMLAWGLVADVDIESEKY 277

Query: 796  RWMGSARLDFYALQRIFRLRKYDGRISFVPAPGFEAYGEP-SYQN-GESRGEVNICNPSQ 623
            RWMGSARLDFYA+QRI  LR+Y+G ISFVPAPGFEAYGEP SY N  E     N C PS+
Sbjct: 278  RWMGSARLDFYAVQRIVHLRQYNGSISFVPAPGFEAYGEPTSYNNISEPTNRHNKCGPSK 337

Query: 622  GENIDPQKGGYCGPKVDVESLSWRKLDGPFVSIWLHNVPWGAEDTMAAPDA--------- 470
             E+++ ++ GY GP +++E++ WR + GPFVS+WLHNVPWG+EDT AAPDA         
Sbjct: 338  EESVNIRQHGYEGPDINLENMDWRTISGPFVSVWLHNVPWGSEDTKAAPDAKFSDGYVDM 397

Query: 469  --------------------------------KVKAVVLEPGPRTEDPTKEGIIDADGEV 386
                                            KVKA++LEPGP TEDPT+ GIID+DGEV
Sbjct: 398  IIMRACPKLSLLSLMSGLSTGSHVNSPYVMYFKVKALILEPGPLTEDPTRGGIIDSDGEV 457

Query: 385  LARGKGTFKCDQKALMAYDKLQITVDQGLVTLFTPI 278
            LARGKG +KCDQK LMAYDKLQITVDQGL TLF+P+
Sbjct: 458  LARGKGAYKCDQKTLMAYDKLQITVDQGLATLFSPV 493


>ref|XP_007211993.1| hypothetical protein PRUPE_ppa004781mg [Prunus persica]
            gi|462407858|gb|EMJ13192.1| hypothetical protein
            PRUPE_ppa004781mg [Prunus persica]
          Length = 491

 Score =  593 bits (1528), Expect = e-166
 Identities = 301/456 (66%), Positives = 350/456 (76%), Gaps = 43/456 (9%)
 Frame = -2

Query: 1516 VEKEVLGFSIEGSRIKIKVVVEGGDEICCVGSGGALMRKSFVFEPSSEDSLRLWCQKLQE 1337
            VEKEVLGF+ EG +I+I+ +VE GD ICCV S GA++RK FVF+P SEDS RLWCQKL+E
Sbjct: 44   VEKEVLGFAAEGPKIRIRALVEDGDGICCVASRGAVVRKEFVFKPLSEDSHRLWCQKLRE 103

Query: 1336 FIDSLDRPKKLLILMNPYGGKKFASKIFLDDVKPLLEDANVEFTLQXXXXXXXXXXXXXL 1157
             IDSL RPK+L + +NP+GG K ASKI+ + VKPL +DAN++FTLQ             L
Sbjct: 104  HIDSLGRPKRLFVFVNPFGGSKSASKIYAEHVKPLFQDANIQFTLQETQYQ--------L 155

Query: 1156 HAKEIAKTLDISKYDGIVCVSGDGILVEVVNGLLEREDWESAIRMPLGVVPAGTGNGMAK 977
            HAKE+AKTLD+SKYDGIVCVSGDGILVEVVNGLLEREDWE+AI+MPLGVVPAGTGNGMAK
Sbjct: 156  HAKEVAKTLDLSKYDGIVCVSGDGILVEVVNGLLEREDWEAAIKMPLGVVPAGTGNGMAK 215

Query: 976  SLLDSVGNPCTASNATLAIIRGHKCSLDVSTILQGETRFFSVLMLAWGLVADIDIESEKY 797
            SLLDSVG PCTASNA LAIIRG+K SLDV+TI QG+T+FFSVLMLAWGLVAD+DIESEKY
Sbjct: 216  SLLDSVGEPCTASNAILAIIRGNKRSLDVATIWQGKTKFFSVLMLAWGLVADVDIESEKY 275

Query: 796  RWMGSARLDFYALQRIFRLRKYDGRISFVPAPGFEAYGEP-SYQN-GESRGEVNICNPSQ 623
            RWMGSARLDFYA+QRI  LR+Y+G ISFVPAPGFE YGEP SY N  E     N C PSQ
Sbjct: 276  RWMGSARLDFYAVQRIVHLRQYNGSISFVPAPGFEIYGEPTSYNNISEPTNHHNKCGPSQ 335

Query: 622  GENIDPQKGGYCGPKVDVESLSWRKLDGPFVSIWLHNVPWGAEDTMAAPDA--------- 470
             E ++ ++ GY GP +++E++ WR ++GPFVS+WLHNVPWG+EDT AAPDA         
Sbjct: 336  EEPVNIRQHGYEGPDINLENMDWRTINGPFVSVWLHNVPWGSEDTKAAPDAKFSDGYLDV 395

Query: 469  --------------------------------KVKAVVLEPGPRTEDPTKEGIIDADGEV 386
                                            KVKA++LEPGP TEDPTK GIID+DGEV
Sbjct: 396  IIMRACPKLSLLSLMSGLSTGSHVNSPYVMYFKVKALILEPGPLTEDPTKGGIIDSDGEV 455

Query: 385  LARGKGTFKCDQKALMAYDKLQITVDQGLVTLFTPI 278
            LARGKG +KCDQK LMAYDKLQITVDQGL TLF+P+
Sbjct: 456  LARGKGAYKCDQKTLMAYDKLQITVDQGLATLFSPV 491


>ref|XP_012091503.1| PREDICTED: sphingosine kinase 1 isoform X1 [Jatropha curcas]
            gi|643703828|gb|KDP20892.1| hypothetical protein
            JCGZ_21363 [Jatropha curcas]
          Length = 490

 Score =  581 bits (1498), Expect = e-163
 Identities = 289/453 (63%), Positives = 336/453 (74%), Gaps = 41/453 (9%)
 Frame = -2

Query: 1516 VEKEVLGFSIEGSRIKIKVVVEGGDEICCVGSGGALMRKSFVFEPSSEDSLRLWCQKLQE 1337
            +EKEVLGF IEG++I+IK +V+ GD ICC GS GAL+RK FVF+   EDS R+WC +L++
Sbjct: 45   IEKEVLGFVIEGAKIRIKAIVDSGDGICCGGSKGALVRKDFVFQSLHEDSPRVWCHRLRD 104

Query: 1336 FIDSLDRPKKLLILMNPYGGKKFASKIFLDDVKPLLEDANVEFTLQXXXXXXXXXXXXXL 1157
            +IDSL RPK+L I +NP+GG K A+K+FLD VKPLLEDA+++ T+Q             L
Sbjct: 105  YIDSLGRPKRLFIFVNPFGGNKSATKVFLDVVKPLLEDADIQITVQETKHQ--------L 156

Query: 1156 HAKEIAKTLDISKYDGIVCVSGDGILVEVVNGLLEREDWESAIRMPLGVVPAGTGNGMAK 977
            HAKE+A TLD++KYDGIVCVSGDGILVEVVNGLL REDW  AI++PLG+VPAGTGNGM K
Sbjct: 157  HAKEVASTLDLTKYDGIVCVSGDGILVEVVNGLLAREDWSDAIKVPLGMVPAGTGNGMVK 216

Query: 976  SLLDSVGNPCTASNATLAIIRGHKCSLDVSTILQGETRFFSVLMLAWGLVADIDIESEKY 797
            SLLDSVG PC  SNA LAIIRGHKCSLDV+TILQGET+FFSVLML+WGLVAD+DIESEKY
Sbjct: 217  SLLDSVGEPCKPSNAILAIIRGHKCSLDVATILQGETKFFSVLMLSWGLVADVDIESEKY 276

Query: 796  RWMGSARLDFYALQRIFRLRKYDGRISFVPAPGFEAYGEPSYQNGESRGEVNICNPSQGE 617
            RWMGS RLDFYALQRIF LR Y+G ISFVP PGFE YGEP+  N E  G+ NICNPSQ +
Sbjct: 277  RWMGSIRLDFYALQRIFHLRHYNGSISFVPGPGFETYGEPTNYNAEFAGKQNICNPSQEQ 336

Query: 616  NIDPQKGGYCGPKVDVESLSWRKLDGPFVSIWLHNVPWGAEDTMAAPDA----------- 470
             +  Q+ GY G   D+ SL WR + GPFVSIWLHNVPWG ED MAAPDA           
Sbjct: 337  PVKAQQRGYQGSDADLISLDWRTISGPFVSIWLHNVPWGGEDIMAAPDAKFSDGYLDLIL 396

Query: 469  ------------------------------KVKAVVLEPGPRTEDPTKEGIIDADGEVLA 380
                                          KVKA +LEPGPR EDPTK GIID DGEVLA
Sbjct: 397  IKECPKLPLLKLMTEMSSGGHVKSPYVIYIKVKAFILEPGPRAEDPTKGGIIDVDGEVLA 456

Query: 379  RGKGTFKCDQKALMAYDKLQITVDQGLVTLFTP 281
            RG G++KC++K LM YDKLQITVD+GL TLF+P
Sbjct: 457  RGNGSYKCEEKTLMVYDKLQITVDKGLATLFSP 489


>ref|XP_006449226.1| hypothetical protein CICLE_v10015071mg [Citrus clementina]
            gi|557551837|gb|ESR62466.1| hypothetical protein
            CICLE_v10015071mg [Citrus clementina]
          Length = 484

 Score =  581 bits (1498), Expect = e-163
 Identities = 295/456 (64%), Positives = 348/456 (76%), Gaps = 43/456 (9%)
 Frame = -2

Query: 1516 VEKEVLGFSIEGSRIKIKVVVEGGDEICCVGSGGALMRKSFVFEPSSEDSLRLWCQKLQE 1337
            +EK+VLGF +EG++I+I+ VV+G DEICC GS G+++RK FVFEP SEDS RLWC+KL++
Sbjct: 42   LEKQVLGFVVEGNKIRIRAVVDGRDEICCGGSAGSIVRKDFVFEPLSEDSKRLWCEKLRD 101

Query: 1336 FIDSLDRPKKLLILMNPYGGKKFASKIFLDDVKPLLEDANVEFTLQXXXXXXXXXXXXXL 1157
            FIDS  RPK+L I +NP+GGKK ASKIFLDDVKPLLEDAN++FT+Q             L
Sbjct: 102  FIDSFGRPKRLYIFVNPFGGKKIASKIFLDDVKPLLEDANIQFTVQETTQQ--------L 153

Query: 1156 HAKEIAKTLDISKYDGIVCVSGDGILVEVVNGLLEREDWESAIRMPLGVVPAGTGNGMAK 977
            HAKEI K LD+SKYDGIVCVSGDGILVEVVNGLLEREDW  AI++PLGVVPAGTGNGM K
Sbjct: 154  HAKEIVKGLDLSKYDGIVCVSGDGILVEVVNGLLEREDWNDAIKVPLGVVPAGTGNGMIK 213

Query: 976  SLLDSVGNPCTASNATLAIIRGHKCSLDVSTILQGETRFFSVLMLAWGLVADIDIESEKY 797
            SLLD VG PC ASNA LA+IRGHK  LDV+TILQG+TRF SVLMLAWGLVADIDIESEKY
Sbjct: 214  SLLDLVGEPCKASNAILAVIRGHKRLLDVTTILQGKTRFHSVLMLAWGLVADIDIESEKY 273

Query: 796  RWMGSARLDFYALQRIFRLRKYDGRISFVPAPGFEAYGEPSYQNGESRGEVNICN--PSQ 623
            RWMGSAR+DFYALQRI  LR+Y+GR+SFVPAPGFE +GEPS     +  E NICN  PSQ
Sbjct: 274  RWMGSARIDFYALQRILYLRQYNGRVSFVPAPGFENHGEPS-----TYSEQNICNPIPSQ 328

Query: 622  GENIDPQKGGYCGPKVDVESLSWRKLDGPFVSIWLHNVPWGAEDTMAAPDA--------- 470
             + I   + GY GP VD+++L WR ++GPFV++WLHNVPWG+E+TMAAPDA         
Sbjct: 329  QQPIKILQQGYQGPDVDLKNLEWRIINGPFVAVWLHNVPWGSENTMAAPDAKFSDGYLDL 388

Query: 469  --------------------------------KVKAVVLEPGPRTEDPTKEGIIDADGEV 386
                                            KVKA +LEPG  T++P +EGIID DGEV
Sbjct: 389  IIIKVCPKLALLSLLSNLNKGGHVKSPYVAYLKVKAFILEPGALTQEPNREGIIDCDGEV 448

Query: 385  LARGKGTFKCDQKALMAYDKLQITVDQGLVTLFTPI 278
            LARGKGT++CDQK+LM+YDKLQITVDQGL TLF+P+
Sbjct: 449  LARGKGTYQCDQKSLMSYDKLQITVDQGLATLFSPV 484


>gb|KDO75739.1| hypothetical protein CISIN_1g011290mg [Citrus sinensis]
          Length = 484

 Score =  581 bits (1497), Expect = e-163
 Identities = 295/456 (64%), Positives = 347/456 (76%), Gaps = 43/456 (9%)
 Frame = -2

Query: 1516 VEKEVLGFSIEGSRIKIKVVVEGGDEICCVGSGGALMRKSFVFEPSSEDSLRLWCQKLQE 1337
            +EK+VLGF +EGS+I+I+ VV+G DEICC G  G+++RK FVFEP SEDS RLWC+KL++
Sbjct: 42   LEKQVLGFVVEGSKIRIRAVVDGRDEICCGGRAGSVVRKDFVFEPLSEDSKRLWCEKLRD 101

Query: 1336 FIDSLDRPKKLLILMNPYGGKKFASKIFLDDVKPLLEDANVEFTLQXXXXXXXXXXXXXL 1157
            FIDS  RPK+L I +NP+GGKK ASKIFLDDVKPLLEDAN++FT+Q             L
Sbjct: 102  FIDSFGRPKRLYIFVNPFGGKKIASKIFLDDVKPLLEDANIQFTVQETTQQ--------L 153

Query: 1156 HAKEIAKTLDISKYDGIVCVSGDGILVEVVNGLLEREDWESAIRMPLGVVPAGTGNGMAK 977
            HAKEI K LD+SKYDGIVCVSGDGILVEVVNGLLEREDW  AI++PLGVVPAGTGNGM K
Sbjct: 154  HAKEIVKVLDLSKYDGIVCVSGDGILVEVVNGLLEREDWNDAIKVPLGVVPAGTGNGMIK 213

Query: 976  SLLDSVGNPCTASNATLAIIRGHKCSLDVSTILQGETRFFSVLMLAWGLVADIDIESEKY 797
            SLLD VG PC ASNA LA+IRGHK  LDV+TILQG+TRF SVLMLAWGLVADIDIESEKY
Sbjct: 214  SLLDLVGEPCKASNAILAVIRGHKRLLDVATILQGKTRFHSVLMLAWGLVADIDIESEKY 273

Query: 796  RWMGSARLDFYALQRIFRLRKYDGRISFVPAPGFEAYGEPSYQNGESRGEVNICN--PSQ 623
            RWMGSAR+DFYALQRI  LR+Y+GR+SFVPAPGFE +GEPS     +  E NICN  PSQ
Sbjct: 274  RWMGSARIDFYALQRILYLRQYNGRVSFVPAPGFENHGEPS-----TYSEQNICNPIPSQ 328

Query: 622  GENIDPQKGGYCGPKVDVESLSWRKLDGPFVSIWLHNVPWGAEDTMAAPDA--------- 470
             + I   + GY GP VD+++L WR ++GPFV++WLHNVPWG+E+TMAAPDA         
Sbjct: 329  QQPIKILQHGYQGPDVDLKNLEWRIINGPFVAVWLHNVPWGSENTMAAPDAKFSDGYLDL 388

Query: 469  --------------------------------KVKAVVLEPGPRTEDPTKEGIIDADGEV 386
                                            KVKA +LEPG  T++P +EGIID DGEV
Sbjct: 389  IIIKDCPKLALFSLLSNLNKGGHVESPYVAYLKVKAFILEPGALTQEPNREGIIDCDGEV 448

Query: 385  LARGKGTFKCDQKALMAYDKLQITVDQGLVTLFTPI 278
            LARGKGT++CDQK+LM+YDKLQITVDQGL TLF+P+
Sbjct: 449  LARGKGTYQCDQKSLMSYDKLQITVDQGLATLFSPV 484


>ref|XP_006467889.1| PREDICTED: sphingosine kinase 1-like [Citrus sinensis]
          Length = 484

 Score =  581 bits (1497), Expect = e-163
 Identities = 295/456 (64%), Positives = 348/456 (76%), Gaps = 43/456 (9%)
 Frame = -2

Query: 1516 VEKEVLGFSIEGSRIKIKVVVEGGDEICCVGSGGALMRKSFVFEPSSEDSLRLWCQKLQE 1337
            +EK+VLGF +EG++I+I+ VV+G DEICC GS G+++RK FVFEP SEDS RLWC+KL++
Sbjct: 42   LEKQVLGFVVEGNKIRIRAVVDGRDEICCGGSAGSVVRKDFVFEPLSEDSKRLWCEKLRD 101

Query: 1336 FIDSLDRPKKLLILMNPYGGKKFASKIFLDDVKPLLEDANVEFTLQXXXXXXXXXXXXXL 1157
            FIDS  RPK+L I +NP+GGKK ASKIFLDDVKPLLEDAN++FT+Q             L
Sbjct: 102  FIDSFGRPKRLYIFVNPFGGKKIASKIFLDDVKPLLEDANIQFTVQETTQQ--------L 153

Query: 1156 HAKEIAKTLDISKYDGIVCVSGDGILVEVVNGLLEREDWESAIRMPLGVVPAGTGNGMAK 977
            HAKEI K LD+SKYDGIVCVSGDGILVEVVNGLLEREDW  AI++PLGVVPAGTGNGM K
Sbjct: 154  HAKEIVKGLDLSKYDGIVCVSGDGILVEVVNGLLEREDWNDAIKVPLGVVPAGTGNGMIK 213

Query: 976  SLLDSVGNPCTASNATLAIIRGHKCSLDVSTILQGETRFFSVLMLAWGLVADIDIESEKY 797
            SLLD VG PC ASNA LA+IRGHK  LDV+TILQG+TRF SVLMLAWGLVADIDIESEKY
Sbjct: 214  SLLDLVGEPCKASNAILAVIRGHKRLLDVATILQGKTRFHSVLMLAWGLVADIDIESEKY 273

Query: 796  RWMGSARLDFYALQRIFRLRKYDGRISFVPAPGFEAYGEPSYQNGESRGEVNICN--PSQ 623
            RWMGSAR+DFYALQRI  LR+Y+GR+SFVPAPGFE +GEPS     +  E NICN  PSQ
Sbjct: 274  RWMGSARIDFYALQRILYLRQYNGRVSFVPAPGFENHGEPS-----TYSEQNICNPIPSQ 328

Query: 622  GENIDPQKGGYCGPKVDVESLSWRKLDGPFVSIWLHNVPWGAEDTMAAPDA--------- 470
             + I   + GY GP VD+++L WR ++GPFV++WLHNVPWG+E+TMAAPDA         
Sbjct: 329  QQPIKILQHGYQGPDVDLKNLEWRIINGPFVAVWLHNVPWGSENTMAAPDAKFSDGYLDL 388

Query: 469  --------------------------------KVKAVVLEPGPRTEDPTKEGIIDADGEV 386
                                            KVKA +LEPG  T++P +EGIID DGEV
Sbjct: 389  IIIKVCPKLALLSLLSNLNKGGHVKSPYVAYLKVKAFILEPGALTQEPNREGIIDCDGEV 448

Query: 385  LARGKGTFKCDQKALMAYDKLQITVDQGLVTLFTPI 278
            LARGKGT++CDQK+LM+YDKLQITVDQGL TLF+P+
Sbjct: 449  LARGKGTYQCDQKSLMSYDKLQITVDQGLATLFSPV 484


>ref|XP_010092628.1| Sphingosine kinase 1 [Morus notabilis] gi|587861994|gb|EXB51817.1|
            Sphingosine kinase 1 [Morus notabilis]
          Length = 492

 Score =  575 bits (1482), Expect = e-161
 Identities = 290/454 (63%), Positives = 340/454 (74%), Gaps = 41/454 (9%)
 Frame = -2

Query: 1516 VEKEVLGFSIEGSRIKIKVVVEGGDEICCVGSGGALMRKSFVFEPSSEDSLRLWCQKLQE 1337
            VEKEVLGF+ +GS+++I+ VVEGG  I C GS GAL+RK+FVF  SSEDS +L C KL+E
Sbjct: 47   VEKEVLGFATDGSKLEIRTVVEGGGGILCFGSRGALVRKNFVFLFSSEDSQKLLCLKLRE 106

Query: 1336 FIDSLDRPKKLLILMNPYGGKKFASKIFLDDVKPLLEDANVEFTLQXXXXXXXXXXXXXL 1157
            FIDSL RPK+L + +NP+GGKK ASKIF D VKPLLEDA+++ TLQ             L
Sbjct: 107  FIDSLGRPKRLYVFVNPFGGKKSASKIFSDQVKPLLEDADIQLTLQETKYQ--------L 158

Query: 1156 HAKEIAKTLDISKYDGIVCVSGDGILVEVVNGLLEREDWESAIRMPLGVVPAGTGNGMAK 977
            HAKE+AKT+D+SKYDGIVCVSGDGILVE+VNGLLER DWE+AI+ PLGVVPAGTGNGMAK
Sbjct: 159  HAKEVAKTMDLSKYDGIVCVSGDGILVEIVNGLLERGDWETAIKTPLGVVPAGTGNGMAK 218

Query: 976  SLLDSVGNPCTASNATLAIIRGHKCSLDVSTILQGETRFFSVLMLAWGLVADIDIESEKY 797
            SLLDSVG PC   NA LAIIRGHK  LDV+TILQGET+FFSVLMLAWGL+ADIDIESEKY
Sbjct: 219  SLLDSVGEPCAVFNAVLAIIRGHKRPLDVTTILQGETKFFSVLMLAWGLIADIDIESEKY 278

Query: 796  RWMGSARLDFYALQRIFRLRKYDGRISFVPAPGFEAYGEPSYQNGESRGEVNICNPSQGE 617
            RWMGSARLDFY LQR+F LRKY+GRISFVPAPGFE YGEP+    E+  + N+  P++ E
Sbjct: 279  RWMGSARLDFYGLQRVFSLRKYNGRISFVPAPGFEGYGEPTSYKSETTSKQNVGGPTEVE 338

Query: 616  NIDPQKGGYCGPKVDVESLSWRKLDGPFVSIWLHNVPWGAEDTMAAPDA----------- 470
             +  Q+ GY GP  D+  + WR ++GPFVS+WLHNVPWG+E+TMAAP A           
Sbjct: 339  PVKLQRHGYQGPDSDLHIMDWRTINGPFVSVWLHNVPWGSENTMAAPQAKFSDGYIDLII 398

Query: 469  ------------------------------KVKAVVLEPGPRTEDPTKEGIIDADGEVLA 380
                                          KVKA +LEPGP  EDPT+EGIID+DGEVLA
Sbjct: 399  MRDCPKLALLSLMGELNNGNHVNSPYVTYLKVKAFILEPGPLAEDPTREGIIDSDGEVLA 458

Query: 379  RGKGTFKCDQKALMAYDKLQITVDQGLVTLFTPI 278
            RGKGT+KCDQK LMAYDK Q+ VDQGL TLF+P+
Sbjct: 459  RGKGTYKCDQKTLMAYDKFQLAVDQGLATLFSPL 492


>gb|KDO75738.1| hypothetical protein CISIN_1g011290mg [Citrus sinensis]
          Length = 489

 Score =  575 bits (1481), Expect = e-161
 Identities = 295/461 (63%), Positives = 347/461 (75%), Gaps = 48/461 (10%)
 Frame = -2

Query: 1516 VEKEVLGFSIEGSRIKIKVVVEGGDEICCVGSGGALMRKSFVFEPSSEDSLRLWCQKLQE 1337
            +EK+VLGF +EGS+I+I+ VV+G DEICC G  G+++RK FVFEP SEDS RLWC+KL++
Sbjct: 42   LEKQVLGFVVEGSKIRIRAVVDGRDEICCGGRAGSVVRKDFVFEPLSEDSKRLWCEKLRD 101

Query: 1336 FIDSLDRPKKLLILMNPYGGKKFASKIFLDDVKPLLEDANVEFTLQXXXXXXXXXXXXXL 1157
            FIDS  RPK+L I +NP+GGKK ASKIFLDDVKPLLEDAN++FT+Q             L
Sbjct: 102  FIDSFGRPKRLYIFVNPFGGKKIASKIFLDDVKPLLEDANIQFTVQETTQQ--------L 153

Query: 1156 HAKEIAKTLDISKYDGIVCVSGDGILVEVVNGLLEREDWESAIRMPLGVVPA-----GTG 992
            HAKEI K LD+SKYDGIVCVSGDGILVEVVNGLLEREDW  AI++PLGVVPA     GTG
Sbjct: 154  HAKEIVKVLDLSKYDGIVCVSGDGILVEVVNGLLEREDWNDAIKVPLGVVPADFLDAGTG 213

Query: 991  NGMAKSLLDSVGNPCTASNATLAIIRGHKCSLDVSTILQGETRFFSVLMLAWGLVADIDI 812
            NGM KSLLD VG PC ASNA LA+IRGHK  LDV+TILQG+TRF SVLMLAWGLVADIDI
Sbjct: 214  NGMIKSLLDLVGEPCKASNAILAVIRGHKRLLDVATILQGKTRFHSVLMLAWGLVADIDI 273

Query: 811  ESEKYRWMGSARLDFYALQRIFRLRKYDGRISFVPAPGFEAYGEPSYQNGESRGEVNICN 632
            ESEKYRWMGSAR+DFYALQRI  LR+Y+GR+SFVPAPGFE +GEPS     +  E NICN
Sbjct: 274  ESEKYRWMGSARIDFYALQRILYLRQYNGRVSFVPAPGFENHGEPS-----TYSEQNICN 328

Query: 631  --PSQGENIDPQKGGYCGPKVDVESLSWRKLDGPFVSIWLHNVPWGAEDTMAAPDA---- 470
              PSQ + I   + GY GP VD+++L WR ++GPFV++WLHNVPWG+E+TMAAPDA    
Sbjct: 329  PIPSQQQPIKILQHGYQGPDVDLKNLEWRIINGPFVAVWLHNVPWGSENTMAAPDAKFSD 388

Query: 469  -------------------------------------KVKAVVLEPGPRTEDPTKEGIID 401
                                                 KVKA +LEPG  T++P +EGIID
Sbjct: 389  GYLDLIIIKDCPKLALFSLLSNLNKGGHVESPYVAYLKVKAFILEPGALTQEPNREGIID 448

Query: 400  ADGEVLARGKGTFKCDQKALMAYDKLQITVDQGLVTLFTPI 278
             DGEVLARGKGT++CDQK+LM+YDKLQITVDQGL TLF+P+
Sbjct: 449  CDGEVLARGKGTYQCDQKSLMSYDKLQITVDQGLATLFSPV 489


>ref|XP_009376260.1| PREDICTED: sphingosine kinase 1 isoform X1 [Pyrus x bretschneideri]
          Length = 495

 Score =  572 bits (1474), Expect = e-160
 Identities = 292/456 (64%), Positives = 337/456 (73%), Gaps = 43/456 (9%)
 Frame = -2

Query: 1516 VEKEVLGFSIEGSRIKIKVVVEGGDEICCVGSGGALMRKSFVFEPSSEDSLRLWCQKLQE 1337
            VEKEVLGF+ EG +I+I+  VEGG  ICC  + GA+ RK  VFEP SEDS RLWCQKL +
Sbjct: 48   VEKEVLGFAAEGPKIRIRAFVEGGAGICCGANRGAVARKDLVFEPLSEDSHRLWCQKLGD 107

Query: 1336 FIDSLDRPKKLLILMNPYGGKKFASKIFLDDVKPLLEDANVEFTLQXXXXXXXXXXXXXL 1157
            +IDSL RPK+L + +NP+GG K ASKI++D VKPL EDA ++FTLQ             L
Sbjct: 108  YIDSLGRPKRLFVFVNPFGGSKSASKIYVDHVKPLFEDAGIQFTLQETQYQ--------L 159

Query: 1156 HAKEIAKTLDISKYDGIVCVSGDGILVEVVNGLLEREDWESAIRMPLGVVPAGTGNGMAK 977
            HAKE+ KTLD+SKYDGIVCVSGDGILVEVVNGLLEREDW++AI++PLGVVPAGTGNGMAK
Sbjct: 160  HAKEVVKTLDLSKYDGIVCVSGDGILVEVVNGLLEREDWDTAIKIPLGVVPAGTGNGMAK 219

Query: 976  SLLDSVGNPCTASNATLAIIRGHKCSLDVSTILQGETRFFSVLMLAWGLVADIDIESEKY 797
            SLLDSVG PCT SNA LAIIRGHK SLDV+TI QG  +FFSVLMLAWGLVAD+DIESEKY
Sbjct: 220  SLLDSVGEPCTPSNAVLAIIRGHKRSLDVATICQGRMKFFSVLMLAWGLVADVDIESEKY 279

Query: 796  RWMGSARLDFYALQRIFRLRKYDGRISFVPAPGFEAYGEP-SYQN-GESRGEVNICNPSQ 623
            RWMGSARLDFYA+QRI  LR+Y+G ISFVPAPGFEAYGEP SY N  E   + N   P+Q
Sbjct: 280  RWMGSARLDFYAVQRIVHLRQYNGSISFVPAPGFEAYGEPTSYSNASEPTNQHNAGAPNQ 339

Query: 622  GENIDPQKGGYCGPKVDVESLSWRKLDGPFVSIWLHNVPWGAEDTMAAPDA--------- 470
             E I  ++ GY GP +++ S+ WR + GPFVSIWLHNVPWG EDT AAPDA         
Sbjct: 340  EELISIRQHGYPGPDINLASMDWRTISGPFVSIWLHNVPWGGEDTKAAPDAKFSDGYIDV 399

Query: 469  --------------------------------KVKAVVLEPGPRTEDPTKEGIIDADGEV 386
                                            KVKA +L+PGP T+DP KEGIID+DGEV
Sbjct: 400  IMMRACPKLSLLSLMSGLSTGSHIKSPYVLYFKVKAFILQPGPLTKDPAKEGIIDSDGEV 459

Query: 385  LARGKGTFKCDQKALMAYDKLQITVDQGLVTLFTPI 278
            LARGKG +KCDQK LM YDKLQ+TVDQGL TLF+P+
Sbjct: 460  LARGKGAYKCDQKTLMVYDKLQVTVDQGLATLFSPV 495


>ref|XP_008364137.1| PREDICTED: sphingosine kinase 1-like isoform X1 [Malus domestica]
          Length = 495

 Score =  567 bits (1462), Expect = e-159
 Identities = 290/456 (63%), Positives = 337/456 (73%), Gaps = 43/456 (9%)
 Frame = -2

Query: 1516 VEKEVLGFSIEGSRIKIKVVVEGGDEICCVGSGGALMRKSFVFEPSSEDSLRLWCQKLQE 1337
            VEKEVLGF+ EG +I+I+  VEGG  ICC  + GA+ RK  VFEP SEDS R WCQKL +
Sbjct: 48   VEKEVLGFAAEGPKIRIRAFVEGGAGICCGANRGAVARKDLVFEPLSEDSHRXWCQKLGD 107

Query: 1336 FIDSLDRPKKLLILMNPYGGKKFASKIFLDDVKPLLEDANVEFTLQXXXXXXXXXXXXXL 1157
            +IDSL RPK+L + +NP+GG K ASKI++D VKPL EDA+++FTLQ             L
Sbjct: 108  YIDSLGRPKRLFVFVNPFGGSKSASKIYVDHVKPLFEDADIQFTLQETQYQ--------L 159

Query: 1156 HAKEIAKTLDISKYDGIVCVSGDGILVEVVNGLLEREDWESAIRMPLGVVPAGTGNGMAK 977
            HAKE+ KTLD+SKYDGIVCVSGDGILVEVVNGLLER+DW++AI++PLGVVPAGTGNGMAK
Sbjct: 160  HAKEVVKTLDLSKYDGIVCVSGDGILVEVVNGLLERDDWDAAIKIPLGVVPAGTGNGMAK 219

Query: 976  SLLDSVGNPCTASNATLAIIRGHKCSLDVSTILQGETRFFSVLMLAWGLVADIDIESEKY 797
            SLLDSVG PCT SNA LAIIRGHK SLDV+TI QG+ +FFSVLMLAWGLVAD+DIESEKY
Sbjct: 220  SLLDSVGEPCTPSNAVLAIIRGHKRSLDVATICQGKMKFFSVLMLAWGLVADVDIESEKY 279

Query: 796  RWMGSARLDFYALQRIFRLRKYDGRISFVPAPGFEAYGEP-SYQN-GESRGEVNICNPSQ 623
            RWMGSARLDFYA+QRI  LR+Y+G ISFVPAPGFE YGEP SY N  E   + N   P+Q
Sbjct: 280  RWMGSARLDFYAVQRIVHLRQYNGSISFVPAPGFETYGEPTSYSNASEPTNQHNAGAPNQ 339

Query: 622  GENIDPQKGGYCGPKVDVESLSWRKLDGPFVSIWLHNVPWGAEDTMAAPDA--------- 470
             E I  ++ GY GP +++ S+ WR + GPFVSIWLHNVP G EDT AAPDA         
Sbjct: 340  EEPISIRQHGYPGPDINLASMDWRTISGPFVSIWLHNVPXGGEDTKAAPDAKFSDGYIDV 399

Query: 469  --------------------------------KVKAVVLEPGPRTEDPTKEGIIDADGEV 386
                                            KVKA +L+PGP TEDPTKEGIID+DGEV
Sbjct: 400  IMMRVCPKLSLLSLMSGLSTGSHIKSPYVLYFKVKAFILQPGPLTEDPTKEGIIDSDGEV 459

Query: 385  LARGKGTFKCDQKALMAYDKLQITVDQGLVTLFTPI 278
            LARGKG +KCDQK LM YDKLQ+TVDQGL TLF+P+
Sbjct: 460  LARGKGAYKCDQKTLMVYDKLQVTVDQGLATLFSPV 495


>ref|XP_007025779.1| Sphingosine kinase 1 isoform 2 [Theobroma cacao]
            gi|508781145|gb|EOY28401.1| Sphingosine kinase 1 isoform
            2 [Theobroma cacao]
          Length = 481

 Score =  567 bits (1460), Expect = e-158
 Identities = 283/445 (63%), Positives = 338/445 (75%), Gaps = 41/445 (9%)
 Frame = -2

Query: 1516 VEKEVLGFSIEGSRIKIKVVVEGGDEICCVGSGGALMRKSFVFEPSSEDSLRLWCQKLQE 1337
            +EKEVLGF++EG+RI++K  VE GD ICC+G+ G L+R+SFVFEP S+DSLRLW QKL++
Sbjct: 47   MEKEVLGFALEGTRIRVKYAVEKGDGICCLGNRGDLVRQSFVFEPLSDDSLRLWSQKLRD 106

Query: 1336 FIDSLDRPKKLLILMNPYGGKKFASKIFLDDVKPLLEDANVEFTLQXXXXXXXXXXXXXL 1157
            +IDSL RPK+LL+ +NPYGGKK A+KIF +DVKP LEDA+V+ T+              L
Sbjct: 107  YIDSLGRPKRLLVFVNPYGGKKSATKIFSEDVKPYLEDADVQITV--------IETKHQL 158

Query: 1156 HAKEIAKTLDISKYDGIVCVSGDGILVEVVNGLLEREDWESAIRMPLGVVPAGTGNGMAK 977
            HAKE+AKTLD+SKYDGIVCVSGDGILVEVVNGLLEREDW +AI++P+G+VPAGTGNGM K
Sbjct: 159  HAKEVAKTLDLSKYDGIVCVSGDGILVEVVNGLLEREDWAAAIKIPIGMVPAGTGNGMVK 218

Query: 976  SLLDSVGNPCTASNATLAIIRGHKCSLDVSTILQGETRFFSVLMLAWGLVADIDIESEKY 797
            SLLD+VG PC+ SNA LA+IRGHKCSLDV+TILQGETRFFSVLMLAWGL+ADIDIESEKY
Sbjct: 219  SLLDAVGQPCSTSNAILAVIRGHKCSLDVATILQGETRFFSVLMLAWGLIADIDIESEKY 278

Query: 796  RWMGSARLDFYALQRIFRLRKYDGRISFVPAPGFEAYGEPSYQNGESRGEVNICNPSQGE 617
            RWMGSARLDFYALQR+  LR Y+G +SFVPAPGFE YGEP+  +GE   E    +P++  
Sbjct: 279  RWMGSARLDFYALQRLLHLRHYNGCVSFVPAPGFEDYGEPTGYHGEPTSEE---SPTEEN 335

Query: 616  NIDPQKGGYCGPKVDVESLSWRKLDGPFVSIWLHNVPWGAEDTMAAPDA----------- 470
            ++  Q+ GY G    +E+  WR + GPF+S+WLHNVPWG+ED MAAP A           
Sbjct: 336  SVKTQRHGYHGSDFKLENKHWRTISGPFISVWLHNVPWGSEDCMAAPKAKFSDGCLDLIM 395

Query: 469  ------------------------------KVKAVVLEPGPRTEDPTKEGIIDADGEVLA 380
                                          KVKA VLEPGPR EDP KEGIID+DGEVLA
Sbjct: 396  VRDSPKLPLLSLMSKMNDGSHVKSPHVTYIKVKAFVLEPGPRVEDPAKEGIIDSDGEVLA 455

Query: 379  RGKGTFKCDQKALMAYDKLQITVDQ 305
            RGKGT+KCDQKALMAYDKLQ+T+DQ
Sbjct: 456  RGKGTYKCDQKALMAYDKLQLTLDQ 480


>ref|XP_007025778.1| Sphingosine kinase 1 isoform 1 [Theobroma cacao]
            gi|508781144|gb|EOY28400.1| Sphingosine kinase 1 isoform
            1 [Theobroma cacao]
          Length = 486

 Score =  567 bits (1460), Expect = e-158
 Identities = 283/445 (63%), Positives = 338/445 (75%), Gaps = 41/445 (9%)
 Frame = -2

Query: 1516 VEKEVLGFSIEGSRIKIKVVVEGGDEICCVGSGGALMRKSFVFEPSSEDSLRLWCQKLQE 1337
            +EKEVLGF++EG+RI++K  VE GD ICC+G+ G L+R+SFVFEP S+DSLRLW QKL++
Sbjct: 47   MEKEVLGFALEGTRIRVKYAVEKGDGICCLGNRGDLVRQSFVFEPLSDDSLRLWSQKLRD 106

Query: 1336 FIDSLDRPKKLLILMNPYGGKKFASKIFLDDVKPLLEDANVEFTLQXXXXXXXXXXXXXL 1157
            +IDSL RPK+LL+ +NPYGGKK A+KIF +DVKP LEDA+V+ T+              L
Sbjct: 107  YIDSLGRPKRLLVFVNPYGGKKSATKIFSEDVKPYLEDADVQITV--------IETKHQL 158

Query: 1156 HAKEIAKTLDISKYDGIVCVSGDGILVEVVNGLLEREDWESAIRMPLGVVPAGTGNGMAK 977
            HAKE+AKTLD+SKYDGIVCVSGDGILVEVVNGLLEREDW +AI++P+G+VPAGTGNGM K
Sbjct: 159  HAKEVAKTLDLSKYDGIVCVSGDGILVEVVNGLLEREDWAAAIKIPIGMVPAGTGNGMVK 218

Query: 976  SLLDSVGNPCTASNATLAIIRGHKCSLDVSTILQGETRFFSVLMLAWGLVADIDIESEKY 797
            SLLD+VG PC+ SNA LA+IRGHKCSLDV+TILQGETRFFSVLMLAWGL+ADIDIESEKY
Sbjct: 219  SLLDAVGQPCSTSNAILAVIRGHKCSLDVATILQGETRFFSVLMLAWGLIADIDIESEKY 278

Query: 796  RWMGSARLDFYALQRIFRLRKYDGRISFVPAPGFEAYGEPSYQNGESRGEVNICNPSQGE 617
            RWMGSARLDFYALQR+  LR Y+G +SFVPAPGFE YGEP+  +GE   E    +P++  
Sbjct: 279  RWMGSARLDFYALQRLLHLRHYNGCVSFVPAPGFEDYGEPTGYHGEPTSEE---SPTEEN 335

Query: 616  NIDPQKGGYCGPKVDVESLSWRKLDGPFVSIWLHNVPWGAEDTMAAPDA----------- 470
            ++  Q+ GY G    +E+  WR + GPF+S+WLHNVPWG+ED MAAP A           
Sbjct: 336  SVKTQRHGYHGSDFKLENKHWRTISGPFISVWLHNVPWGSEDCMAAPKAKFSDGCLDLIM 395

Query: 469  ------------------------------KVKAVVLEPGPRTEDPTKEGIIDADGEVLA 380
                                          KVKA VLEPGPR EDP KEGIID+DGEVLA
Sbjct: 396  VRDSPKLPLLSLMSKMNDGSHVKSPHVTYIKVKAFVLEPGPRVEDPAKEGIIDSDGEVLA 455

Query: 379  RGKGTFKCDQKALMAYDKLQITVDQ 305
            RGKGT+KCDQKALMAYDKLQ+T+DQ
Sbjct: 456  RGKGTYKCDQKALMAYDKLQLTLDQ 480


>ref|XP_002524674.1| Sphingosine kinase, putative [Ricinus communis]
            gi|223536035|gb|EEF37693.1| Sphingosine kinase, putative
            [Ricinus communis]
          Length = 479

 Score =  565 bits (1456), Expect = e-158
 Identities = 286/454 (62%), Positives = 334/454 (73%), Gaps = 41/454 (9%)
 Frame = -2

Query: 1516 VEKEVLGFSIEGSRIKIKVVVEGGDEICCVGSGGALMRKSFVFEPSSEDSLRLWCQKLQE 1337
            VEKEVLGF IEGS+I++K +++ GD ICC G+ GAL+RK FVF+P +EDS R+ C +L++
Sbjct: 42   VEKEVLGFVIEGSKIRVKTIIDNGDGICCAGNSGALVRKDFVFQPLTEDSQRVLCNRLRD 101

Query: 1336 FIDSLDRPKKLLILMNPYGGKKFASKIFLDDVKPLLEDANVEFTLQXXXXXXXXXXXXXL 1157
            ++DSL RPK+LL+ +NP+GGK+ ASKIF D VKPLLEDA+V+ TLQ             L
Sbjct: 102  YLDSLGRPKRLLVFVNPFGGKRSASKIFFDTVKPLLEDADVQITLQETKHQ--------L 153

Query: 1156 HAKEIAKTLDISKYDGIVCVSGDGILVEVVNGLLEREDWESAIRMPLGVVPAGTGNGMAK 977
            HAKE+  TLDISKYDGIVCVSGDGILVEVVNGLL REDW  AI++PLG+VPAGT NGMAK
Sbjct: 154  HAKEVTSTLDISKYDGIVCVSGDGILVEVVNGLLAREDWRDAIKLPLGMVPAGTSNGMAK 213

Query: 976  SLLDSVGNPCTASNATLAIIRGHKCSLDVSTILQGETRFFSVLMLAWGLVADIDIESEKY 797
            SLLDSVG PC ASNA LAIIRGHKCSLDV+TILQGET+FFSVLML+WGLVADIDIESEKY
Sbjct: 214  SLLDSVGEPCKASNAVLAIIRGHKCSLDVATILQGETKFFSVLMLSWGLVADIDIESEKY 273

Query: 796  RWMGSARLDFYALQRIFRLRKYDGRISFVPAPGFEAYGEPSYQNGESRGEVNICNPSQGE 617
            RWMGSAR+DFYA+QRIF LR Y+G ISFVPAPGFE YG P+  N ES         S+ E
Sbjct: 274  RWMGSARIDFYAVQRIFHLRHYNGCISFVPAPGFETYGVPTSYNAES--------TSKQE 325

Query: 616  NIDPQKGGYCGPKVDVESLSWRKLDGPFVSIWLHNVPWGAEDTMAAPDA----------- 470
                 + GY GP V++ +L WR + GPFVSIWLHNVPWG ED MAAPDA           
Sbjct: 326  QPLKTQHGYQGPDVNLVNLDWRMISGPFVSIWLHNVPWGGEDVMAAPDAKFSDGYLDLIL 385

Query: 469  ------------------------------KVKAVVLEPGPRTEDPTKEGIIDADGEVLA 380
                                          KVKA +LEPGPRT+DPTK GIID DGEVLA
Sbjct: 386  IQQCPKLSLLALMTALNNGDHVKSPYVIYLKVKAFILEPGPRTDDPTKGGIIDVDGEVLA 445

Query: 379  RGKGTFKCDQKALMAYDKLQITVDQGLVTLFTPI 278
            RG G++KCDQK+LM YDKL + VDQGL TLF+P+
Sbjct: 446  RGNGSYKCDQKSLMVYDKLHMMVDQGLATLFSPV 479


>ref|XP_004485708.1| PREDICTED: sphingosine kinase 1 isoform X1 [Cicer arietinum]
          Length = 489

 Score =  564 bits (1454), Expect = e-158
 Identities = 282/454 (62%), Positives = 341/454 (75%), Gaps = 41/454 (9%)
 Frame = -2

Query: 1516 VEKEVLGFSIEGSRIKIKVVVEGGDEICCVGSGGALMRKSFVFEPSSEDSLRLWCQKLQE 1337
            VEKEV+GF   G  IK+K +VE  D  C  G+ G L+R   VF+PSSE+S RLWCQKL+E
Sbjct: 44   VEKEVIGFVTNGPCIKLKTLVEARDGCCTTGAAGRLVRNDVVFKPSSEESHRLWCQKLRE 103

Query: 1336 FIDSLDRPKKLLILMNPYGGKKFASKIFLDDVKPLLEDANVEFTLQXXXXXXXXXXXXXL 1157
            FIDSL RPK+LL+ +NP+GGKK A KI  + VKPLLEDA +E T+Q             L
Sbjct: 104  FIDSLGRPKRLLVFVNPFGGKKSAVKILYEQVKPLLEDAQIELTIQETQHQ--------L 155

Query: 1156 HAKEIAKTLDISKYDGIVCVSGDGILVEVVNGLLEREDWESAIRMPLGVVPAGTGNGMAK 977
            HAKE+A+++DI+K+DGIVCVSGDGILVEVVNGLL+R+DWE+AI+MPLGVVPAGTGNGMAK
Sbjct: 156  HAKEVARSVDITKHDGIVCVSGDGILVEVVNGLLQRDDWETAIKMPLGVVPAGTGNGMAK 215

Query: 976  SLLDSVGNPCTASNATLAIIRGHKCSLDVSTILQGETRFFSVLMLAWGLVADIDIESEKY 797
            SLLDSVG+PC  +NA LAIIRGHK  LDV+TI QGETRFFS+LMLAWGL+ADIDIESEKY
Sbjct: 216  SLLDSVGDPCAVANAVLAIIRGHKRQLDVATIAQGETRFFSILMLAWGLIADIDIESEKY 275

Query: 796  RWMGSARLDFYALQRIFRLRKYDGRISFVPAPGFEAYGEPSYQNGESRGEVNICNPSQGE 617
            RWMGSARLDFYAL R F +R+Y+G +SFVPAPGFE+YGE +   G+S  + N  +PS+GE
Sbjct: 276  RWMGSARLDFYALCRFFNMRQYNGSVSFVPAPGFESYGESTSYPGKSTIKGNNSDPSEGE 335

Query: 616  NIDPQKGGYCGPKVDVESLSWRKLDGPFVSIWLHNVPWGAEDTMAAPDA----------- 470
            + + Q   Y GP+VD+E+L+WR + GPF+S+WLHNVPWGAEDTMAAPDA           
Sbjct: 336  HFNLQTHCYQGPEVDLENLNWRVITGPFISVWLHNVPWGAEDTMAAPDAKFSDGYLDLII 395

Query: 469  ------------------------------KVKAVVLEPGPRTEDPTKEGIIDADGEVLA 380
                                          KVKA +LEPGPRT+D  KEGI+D+DGEVLA
Sbjct: 396  MKNCPKLQLLSMMSELNNGGHVKSPYVTYLKVKAFILEPGPRTKDQEKEGILDSDGEVLA 455

Query: 379  RGKGTFKCDQKALMAYDKLQITVDQGLVTLFTPI 278
            RGKGT+KC+QK+LM+YDKLQITVD+GL TLF P+
Sbjct: 456  RGKGTYKCEQKSLMSYDKLQITVDKGLATLFAPV 489


>ref|XP_004293517.1| PREDICTED: sphingosine kinase 1-like isoform X1 [Fragaria vesca
            subsp. vesca]
          Length = 497

 Score =  561 bits (1447), Expect = e-157
 Identities = 287/458 (62%), Positives = 338/458 (73%), Gaps = 46/458 (10%)
 Frame = -2

Query: 1516 VEKEVLGFSIEGSRIKIKVVVEGGDEICCV----GSGGALMRKSFVFEPSSEDSLRLWCQ 1349
            VEKEVLG  +EG +I+I  +V  G  ICCV    G GGAL+R+  VFEP SED  +LWCQ
Sbjct: 44   VEKEVLGLKVEGPKIRIGALVHAGAGICCVASGGGGGGALVRRDLVFEPLSEDLRKLWCQ 103

Query: 1348 KLQEFIDSLDRPKKLLILMNPYGGKKFASKIFLDDVKPLLEDANVEFTLQXXXXXXXXXX 1169
            KL +FIDSL RP++LL+ +NP+GG K ASKIF D+VKPL +DA V+ TLQ          
Sbjct: 104  KLLDFIDSLGRPRRLLVFVNPFGGSKAASKIFADEVKPLFDDAGVQLTLQETQYQ----- 158

Query: 1168 XXXLHAKEIAKTLDISKYDGIVCVSGDGILVEVVNGLLEREDWESAIRMPLGVVPAGTGN 989
               LHAKE+ KTLD+SKYDGIVCVSGDG+LVEVVNGLLEREDW++AI+MPLGVVPAGTGN
Sbjct: 159  ---LHAKEVVKTLDLSKYDGIVCVSGDGVLVEVVNGLLEREDWDTAIKMPLGVVPAGTGN 215

Query: 988  GMAKSLLDSVGNPCTASNATLAIIRGHKCSLDVSTILQGETRFFSVLMLAWGLVADIDIE 809
            GMAKSLL+SVG PC  +NA LAIIRGHK SLDVSTI QG+T+FFSVLMLAWGLVAD+DIE
Sbjct: 216  GMAKSLLESVGEPCKVTNAVLAIIRGHKRSLDVSTIWQGKTKFFSVLMLAWGLVADVDIE 275

Query: 808  SEKYRWMGSARLDFYALQRIFRLRKYDGRISFVPAPGFEAYGEP-SYQNGESRGEVNICN 632
            SEKYRWMGSARLD YA+QRI  LR+Y+G ISFVPAPGFE +GEP SY++G   GE    +
Sbjct: 276  SEKYRWMGSARLDIYAIQRIVHLRQYNGSISFVPAPGFEGFGEPTSYKDG---GESTNTD 332

Query: 631  PSQGENIDPQKGGYCGPKVDVESLSWRKLDGPFVSIWLHNVPWGAEDTMAAPDA------ 470
            PSQ + +  ++ GY GP + +E+++WR ++GPFVS+WLHNVPWG E+T AAPDA      
Sbjct: 333  PSQEKPVKVRQLGYEGPDISLENMNWRTIEGPFVSVWLHNVPWGGEETKAAPDAEFSDGY 392

Query: 469  -----------------------------------KVKAVVLEPGPRTEDPTKEGIIDAD 395
                                               KVKA VLEPG R EDPTKEGI+D+D
Sbjct: 393  LDVIIMKACPKLSLLSLMTGLSRGTHVKSPYVSYFKVKAFVLEPGARAEDPTKEGIVDSD 452

Query: 394  GEVLARGKGTFKCDQKALMAYDKLQITVDQGLVTLFTP 281
            GEVLARGKG +KC QK LM+YDKLQITVDQGL TLFTP
Sbjct: 453  GEVLARGKGAYKCQQKTLMSYDKLQITVDQGLATLFTP 490


>ref|XP_014506993.1| PREDICTED: sphingosine kinase 1-like [Vigna radiata var. radiata]
          Length = 486

 Score =  559 bits (1440), Expect = e-156
 Identities = 285/454 (62%), Positives = 337/454 (74%), Gaps = 41/454 (9%)
 Frame = -2

Query: 1516 VEKEVLGFSIEGSRIKIKVVVEGGDEICCVGSGGALMRKSFVFEPSSEDSLRLWCQKLQE 1337
            +EKEV+GF+ +G  I++K VVEG D  C  GS G ++R   VF PSSE+S RLWC+KL+E
Sbjct: 41   IEKEVIGFATDGLNIRLKTVVEGADGCCGCGSRGKVVRNDVVFRPSSEESHRLWCRKLKE 100

Query: 1336 FIDSLDRPKKLLILMNPYGGKKFASKIFLDDVKPLLEDANVEFTLQXXXXXXXXXXXXXL 1157
            FIDSL RPK+L + +NP+GG+KFA+ IF D VKPLLEDA V  T+Q             L
Sbjct: 101  FIDSLGRPKRLFVFVNPFGGRKFAANIFRDHVKPLLEDAQVHLTVQETKHQ--------L 152

Query: 1156 HAKEIAKTLDISKYDGIVCVSGDGILVEVVNGLLEREDWESAIRMPLGVVPAGTGNGMAK 977
            HAK++ ++LD SKYDGIVCVSGDGILVEVVNGLL+REDW++AI++PLGVVPAGTGNGMAK
Sbjct: 153  HAKQVVQSLDFSKYDGIVCVSGDGILVEVVNGLLQREDWDTAIKIPLGVVPAGTGNGMAK 212

Query: 976  SLLDSVGNPCTASNATLAIIRGHKCSLDVSTILQGETRFFSVLMLAWGLVADIDIESEKY 797
            SLLDSVG+PCT +NA LAIIRGHK SLDV+TI QGETRFFSVLMLAWGLVADIDIESEKY
Sbjct: 213  SLLDSVGDPCTITNAVLAIIRGHKRSLDVATITQGETRFFSVLMLAWGLVADIDIESEKY 272

Query: 796  RWMGSARLDFYALQRIFRLRKYDGRISFVPAPGFEAYGEPSYQNGESRGEVNICNPSQGE 617
            RWMGSAR+DFYAL RIF LR Y+G + FVPAPGFEAYGE     G S  +  I +   GE
Sbjct: 273  RWMGSARIDFYALTRIFHLRHYEGCLYFVPAPGFEAYGETISYPGSSASKRIISDQMDGE 332

Query: 616  NIDPQKGGYCGPKVDVESLSWRKLDGPFVSIWLHNVPWGAEDTMAAPDA----------- 470
            +   ++ GY GP++D+E+LSWR L+GPF+S+WLHNVPWGAE+T AAP+A           
Sbjct: 333  SGKLKRLGYQGPEIDLENLSWRVLNGPFISVWLHNVPWGAENTKAAPNAEFSDGYLDLII 392

Query: 469  ------------------------------KVKAVVLEPGPRTEDPTKEGIIDADGEVLA 380
                                          KVK +VLEPGPR  D  KEGIIDADGEVLA
Sbjct: 393  MKNCPKLPLLSLMSDLNNGGHVKSPHVMYLKVKVLVLEPGPRRGDQEKEGIIDADGEVLA 452

Query: 379  RGKGTFKCDQKALMAYDKLQITVDQGLVTLFTPI 278
            RGKG+++C+QKALMAYDKLQITVDQGL TLFTPI
Sbjct: 453  RGKGSYQCEQKALMAYDKLQITVDQGLATLFTPI 486


>ref|XP_013462482.1| D-erythro-sphingosine kinase/diacylglycerol kinase [Medicago
            truncatula] gi|657396557|gb|KEH36517.1|
            D-erythro-sphingosine kinase/diacylglycerol kinase
            [Medicago truncatula]
          Length = 484

 Score =  559 bits (1440), Expect = e-156
 Identities = 280/454 (61%), Positives = 339/454 (74%), Gaps = 41/454 (9%)
 Frame = -2

Query: 1516 VEKEVLGFSIEGSRIKIKVVVEGGDEICCVGSGGALMRKSFVFEPSSEDSLRLWCQKLQE 1337
            VEKEVLGF   GS IK+K +VE  D  C  G  G L+R   VF+PSSE++LRLWC KL E
Sbjct: 39   VEKEVLGFVSSGSYIKLKTLVEARDGCCTTGEAGRLVRNDVVFKPSSEENLRLWCLKLHE 98

Query: 1336 FIDSLDRPKKLLILMNPYGGKKFASKIFLDDVKPLLEDANVEFTLQXXXXXXXXXXXXXL 1157
            FIDSL RPKKLL+ +NP+GGKK A KIF + VKPL +DA ++ T+Q             L
Sbjct: 99   FIDSLGRPKKLLVFVNPFGGKKCAVKIFAEQVKPLFDDAQIQLTIQETKHQ--------L 150

Query: 1156 HAKEIAKTLDISKYDGIVCVSGDGILVEVVNGLLEREDWESAIRMPLGVVPAGTGNGMAK 977
            HAKE+A++LDISK+DGIVC+SGDGILVEVVNGLL+REDW++AI+ PLG+VPAGTGNGMAK
Sbjct: 151  HAKEVARSLDISKHDGIVCISGDGILVEVVNGLLQREDWDTAIKTPLGIVPAGTGNGMAK 210

Query: 976  SLLDSVGNPCTASNATLAIIRGHKCSLDVSTILQGETRFFSVLMLAWGLVADIDIESEKY 797
            SLLDSVG+PC  +NA LAIIRGHK  LDV+TI QGETRFFS+LMLAWGL+ADIDIESEKY
Sbjct: 211  SLLDSVGDPCAIANAVLAIIRGHKRQLDVATITQGETRFFSILMLAWGLIADIDIESEKY 270

Query: 796  RWMGSARLDFYALQRIFRLRKYDGRISFVPAPGFEAYGEPSYQNGESRGEVNICNPSQGE 617
            RWMGSARLDFYA+ R+F LR Y+G +SFVPAPGFE+YGE +   G+S    N  +PS+GE
Sbjct: 271  RWMGSARLDFYAVCRLFNLRLYNGSVSFVPAPGFESYGESTSYPGKSTIRGNSSDPSEGE 330

Query: 616  NIDPQKGGYCGPKVDVESLSWRKLDGPFVSIWLHNVPWGAEDTMAAPDA----------- 470
            +++ Q   Y GP++D+E+++WR ++GPF+S+W+HNVPWGAEDTMAAPDA           
Sbjct: 331  HVNLQTLCYQGPEIDLENMNWRVINGPFISVWVHNVPWGAEDTMAAPDAKFSDGYLDLII 390

Query: 469  ------------------------------KVKAVVLEPGPRTEDPTKEGIIDADGEVLA 380
                                          KVKA  LEPG RT+D  KEGIID+DGEVLA
Sbjct: 391  TMNCPKLHLLSMMSELNKGGHVKSPYVTYLKVKAFSLEPGTRTKDLEKEGIIDSDGEVLA 450

Query: 379  RGKGTFKCDQKALMAYDKLQITVDQGLVTLFTPI 278
            RG+GT+KC+QKALMAYDKLQITVD+GL TLFTP+
Sbjct: 451  RGRGTYKCEQKALMAYDKLQITVDKGLATLFTPM 484


>ref|XP_002317243.1| diacylglycerol kinase family protein [Populus trichocarpa]
            gi|222860308|gb|EEE97855.1| diacylglycerol kinase family
            protein [Populus trichocarpa]
          Length = 494

 Score =  558 bits (1439), Expect = e-156
 Identities = 284/456 (62%), Positives = 332/456 (72%), Gaps = 43/456 (9%)
 Frame = -2

Query: 1516 VEKEVLGFSIEGSRIKIKVVVEGGDEICCVGS--GGALMRKSFVFEPSSEDSLRLWCQKL 1343
            VEKEVLGF+I+GS+I IK V E  D I C  S  GGAL RK FVFEP S++SL LWCQ L
Sbjct: 45   VEKEVLGFTIQGSKIIIKAVTEKRDGIFCSASAGGGALARKDFVFEPLSDESLHLWCQHL 104

Query: 1342 QEFIDSLDRPKKLLILMNPYGGKKFASKIFLDDVKPLLEDANVEFTLQXXXXXXXXXXXX 1163
            +++I+SL RPK+L I +NP+GGKK A KI+ D VKPLLEDA+V+ T+Q            
Sbjct: 105  RDYINSLGRPKRLFIFVNPFGGKKSALKIYFDVVKPLLEDADVQITVQETKYQ------- 157

Query: 1162 XLHAKEIAKTLDISKYDGIVCVSGDGILVEVVNGLLEREDWESAIRMPLGVVPAGTGNGM 983
             LHAKE+ + +D++KYDGIVCVSGDGILVEVVNGLLEREDW +AI+MPLG VPAGTGNGM
Sbjct: 158  -LHAKEVVRAMDLTKYDGIVCVSGDGILVEVVNGLLEREDWNAAIKMPLGTVPAGTGNGM 216

Query: 982  AKSLLDSVGNPCTASNATLAIIRGHKCSLDVSTILQGETRFFSVLMLAWGLVADIDIESE 803
             KS LDS G PCTASNA +AIIRGHKCSLDV+TILQG+T+FFSVLM AWGLVADIDIESE
Sbjct: 217  VKSTLDSAGEPCTASNAVVAIIRGHKCSLDVATILQGDTKFFSVLMFAWGLVADIDIESE 276

Query: 802  KYRWMGSARLDFYALQRIFRLRKYDGRISFVPAPGFEAYGEPSYQNGESRGEVNICNPSQ 623
            KYRWMGSARLDFY LQR+  LR+Y GRISFVPAPGFEAYGEP+  NGE     +  NP Q
Sbjct: 277  KYRWMGSARLDFYGLQRMLCLRQYSGRISFVPAPGFEAYGEPTRYNGEFTSTQSSINPGQ 336

Query: 622  GENIDPQKGGYCGPKVDVESLSWRKLDGPFVSIWLHNVPWGAEDTMAAPDA--------- 470
             +++  ++  Y GP VD+ +L WR ++GPF+S+WLHNVPWG E TMAAPDA         
Sbjct: 337  EQHVKAEQYSYQGPDVDLTNLEWRTINGPFISVWLHNVPWGGEGTMAAPDAKFADGNLDL 396

Query: 469  --------------------------------KVKAVVLEPGPRTEDPTKEGIIDADGEV 386
                                            KVKA +LEPG RT+DPT+ GIID DGEV
Sbjct: 397  ILIKDCPKLGLLALMTNLSDGGHVKSPHVMYLKVKAFILEPGQRTKDPTRGGIIDIDGEV 456

Query: 385  LARGKGTFKCDQKALMAYDKLQITVDQGLVTLFTPI 278
            LARG GT+K DQK LM YDKLQIT+DQGL TLF P+
Sbjct: 457  LARGNGTYKHDQKTLMTYDKLQITMDQGLATLFCPV 492