BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Coptis25_contig00020737
         (1120 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002280254.1| PREDICTED: bifunctional dihydrofolate reduct...   570   e-160
ref|XP_002306118.1| dihydrofolate reductase-thymidylate synthase...   557   e-156
ref|XP_002512938.1| bifunctional dihydrofolate reductase-thymidy...   554   e-155
ref|XP_004148833.1| PREDICTED: bifunctional dihydrofolate reduct...   553   e-155
ref|NP_001238644.1| bifunctional dihydrofolate reductase-thymidy...   546   e-153

>ref|XP_002280254.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate
            synthase-like [Vitis vinifera]
          Length = 524

 Score =  570 bits (1468), Expect = e-160
 Identities = 279/352 (79%), Positives = 311/352 (88%), Gaps = 4/352 (1%)
 Frame = +1

Query: 76   ADIVANLLNGSSN----PLRTYQVVVAATQTMGIGKDGKLPWNLPSDLKFFKEVTMVTSD 243
            +D V +L NG++N    P RTYQVVVAAT+ MGIGKDGKLPW LPSD+K FK++TM  +D
Sbjct: 3    SDTVVSLPNGNANIQPDPQRTYQVVVAATRDMGIGKDGKLPWRLPSDMKIFKDITMTVAD 62

Query: 244  PGKRNAVIMGRKTWESIPPEKRPLPGRLNVVLTRSGSFDIATAENVVICGSMTSALELLA 423
              K+NAVIMGRKTWESIP E RPLPGRLNVVLTRSGSFDIATAENVVICGSM SALELLA
Sbjct: 63   TVKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVICGSMASALELLA 122

Query: 424  ASPYCLSIEKVFVIGGGQILKEALNAPECDAVHITEISTSIECDTFMPPVDHSIYRPWYS 603
            ASPYCLSIEKVFVIGGGQIL+EALNAP CDA+HITEI TS ECDTF+P +D  +++PWYS
Sbjct: 123  ASPYCLSIEKVFVIGGGQILREALNAPGCDAIHITEIETSFECDTFIPAIDSLVFQPWYS 182

Query: 604  SFPLVENNILLSYVSYIRVRQSALESVTFNNGDISNGSNSVKLEVDKSSSLPKMIFEKHK 783
            SFPLVENNI  S+++Y+RVR SA ES   NNGD  +G  S+K EV K S LPKMIFE+H+
Sbjct: 183  SFPLVENNIRYSFMTYVRVRSSADESQIQNNGD--SGLESIKFEVKKFSFLPKMIFERHE 240

Query: 784  EYMYLKLVQDIISNGIQKDDRTGTGTLSKFGCQMRFNLRKSFPLLTTKKVFWRGVVEELL 963
            EY+YL+LV+DIISNG+Q+DDRTGTGTLSKFGCQMRFNLRK+FPLLTTKKVFWRGVVEELL
Sbjct: 241  EYIYLRLVEDIISNGVQRDDRTGTGTLSKFGCQMRFNLRKTFPLLTTKKVFWRGVVEELL 300

Query: 964  WFISGSTNAKVLQEKGIRIWDGNASRDYLDSIGLTDREDGDLGPIYGFQWRH 1119
            WFISGSTNAKVLQEKGI IWDGNASRDYLDSIGL DRE+GDLGPIYGFQWRH
Sbjct: 301  WFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLADREEGDLGPIYGFQWRH 352


>ref|XP_002306118.1| dihydrofolate reductase-thymidylate synthase [Populus trichocarpa]
            gi|222849082|gb|EEE86629.1| dihydrofolate
            reductase-thymidylate synthase [Populus trichocarpa]
          Length = 528

 Score =  557 bits (1435), Expect = e-156
 Identities = 272/353 (77%), Positives = 310/353 (87%), Gaps = 6/353 (1%)
 Frame = +1

Query: 79   DIVANLLNGSSN-----PLRTYQVVVAATQTMGIGKDGKLPWNLPSDLKFFKEVTMVTSD 243
            D VANL NG++N     P +TYQVVVAAT+ MGIGKDGKLPW LPSDLKFFK++T+ T D
Sbjct: 4    DSVANLSNGNANTQQSDPRKTYQVVVAATKDMGIGKDGKLPWKLPSDLKFFKDLTLTTMD 63

Query: 244  PGKRNAVIMGRKTWESIPPEKRPLPGRLNVVLTRSGSFDIATAENVVICGSMTSALELLA 423
             GK+NAVIMGRKTWESIP E RPLPGRLNVVLTRSGSFDIATAENVVICGSM SALELLA
Sbjct: 64   SGKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVICGSMGSALELLA 123

Query: 424  ASPYCLSIEKVFVIGGGQILKEALNAPECDAVHITEISTSIECDTFMPPVDHSIYRPWYS 603
            ASPYCLSIEKVFVIGGGQIL+E+LNAP CDA+HITEI T  +CDTF+P +D S+++PWYS
Sbjct: 124  ASPYCLSIEKVFVIGGGQILRESLNAPGCDAIHITEIETDFDCDTFIPAIDTSVFQPWYS 183

Query: 604  SFPLVENNILLSYVSYIRVRQSALESVTFNNGDISNG-SNSVKLEVDKSSSLPKMIFEKH 780
            SFP VEN+I   + +Y+RVR S +ES + NNG+ S+G S + K EV K S LPKM+FE+H
Sbjct: 184  SFPKVENDIRHCFTTYVRVRSSTIESHSQNNGENSDGNSENSKFEVKKFSFLPKMVFERH 243

Query: 781  KEYMYLKLVQDIISNGIQKDDRTGTGTLSKFGCQMRFNLRKSFPLLTTKKVFWRGVVEEL 960
            +EY+YL++VQDIIS+G  KDDRTGTGTLSKFGCQMRFNLRK+FPLLTTKKVFWRGVVEEL
Sbjct: 244  EEYLYLRMVQDIISDGNLKDDRTGTGTLSKFGCQMRFNLRKNFPLLTTKKVFWRGVVEEL 303

Query: 961  LWFISGSTNAKVLQEKGIRIWDGNASRDYLDSIGLTDREDGDLGPIYGFQWRH 1119
            LWFISGST+AKVLQEKGI IWDGNASR+YLDSIGL DRE+GDLGP+YGFQWRH
Sbjct: 304  LWFISGSTSAKVLQEKGIHIWDGNASREYLDSIGLKDREEGDLGPVYGFQWRH 356


>ref|XP_002512938.1| bifunctional dihydrofolate reductase-thymidylate synthase, putative
            [Ricinus communis] gi|223547949|gb|EEF49441.1|
            bifunctional dihydrofolate reductase-thymidylate
            synthase, putative [Ricinus communis]
          Length = 528

 Score =  554 bits (1427), Expect = e-155
 Identities = 273/357 (76%), Positives = 311/357 (87%), Gaps = 6/357 (1%)
 Frame = +1

Query: 67   MAGADIVANLLNGSSN-----PLRTYQVVVAATQTMGIGKDGKLPWNLPSDLKFFKEVTM 231
            MAG D  ANL NG++N     P RTYQVVVAAT+ MGIGKDGKLPW LPSDLKFFK+VT+
Sbjct: 1    MAG-DTKANLSNGNANIEQHDPRRTYQVVVAATRDMGIGKDGKLPWRLPSDLKFFKDVTL 59

Query: 232  VTSDPGKRNAVIMGRKTWESIPPEKRPLPGRLNVVLTRSGSFDIATAENVVICGSMTSAL 411
             T+D GK+NAVIMGRKTWESIP E RPLPGRLNVVLTRSGSFDIATAENVV+CGS  SAL
Sbjct: 60   TTTDSGKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVMCGSFASAL 119

Query: 412  ELLAASPYCLSIEKVFVIGGGQILKEALNAPECDAVHITEISTSIECDTFMPPVDHSIYR 591
            ELLAASPYCLSIEKV+VIGGGQIL+EALNAP CDAVHITEI TS +CDTF+P +D SI+ 
Sbjct: 120  ELLAASPYCLSIEKVYVIGGGQILREALNAPGCDAVHITEIETSFDCDTFIPAIDSSIFH 179

Query: 592  PWYSSFPLVENNILLSYVSYIRVRQSALESVTFNNG-DISNGSNSVKLEVDKSSSLPKMI 768
            PWY SFP+VENNI  S+ +Y+RVR SA+ES   ++G    + S + K +V K S LPKM+
Sbjct: 180  PWYLSFPMVENNIRYSFATYVRVRSSAVESNGHDSGLSSESSSENSKFDVKKFSFLPKMV 239

Query: 769  FEKHKEYMYLKLVQDIISNGIQKDDRTGTGTLSKFGCQMRFNLRKSFPLLTTKKVFWRGV 948
            F++H+E++YL+LVQ+IIS+GI KDDRTGTGTLSKFGCQ+RFNLRK+FPLLTTKKVFWRGV
Sbjct: 240  FDRHEEFLYLRLVQEIISDGILKDDRTGTGTLSKFGCQVRFNLRKTFPLLTTKKVFWRGV 299

Query: 949  VEELLWFISGSTNAKVLQEKGIRIWDGNASRDYLDSIGLTDREDGDLGPIYGFQWRH 1119
            VEELLWFISGSTNAKVLQEKGI IWDGNASRDYLDSIGL +RE+GDLGP+YGFQWRH
Sbjct: 300  VEELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLKNREEGDLGPVYGFQWRH 356


>ref|XP_004148833.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate
            synthase-like [Cucumis sativus]
            gi|449507353|ref|XP_004163007.1| PREDICTED: bifunctional
            dihydrofolate reductase-thymidylate synthase-like
            [Cucumis sativus]
          Length = 527

 Score =  553 bits (1425), Expect = e-155
 Identities = 266/356 (74%), Positives = 308/356 (86%)
 Frame = +1

Query: 52   LSIDRMAGADIVANLLNGSSNPLRTYQVVVAATQTMGIGKDGKLPWNLPSDLKFFKEVTM 231
            ++ D +  ++ +AN+ N   +P RTYQVVVAAT+ +GIGK GKLPW LPSD+KFFK +T+
Sbjct: 1    MAADPLTSSNGIANV-NSPPDPRRTYQVVVAATENLGIGKGGKLPWRLPSDIKFFKNITI 59

Query: 232  VTSDPGKRNAVIMGRKTWESIPPEKRPLPGRLNVVLTRSGSFDIATAENVVICGSMTSAL 411
             TSDPGKRNAV+MGRKTWES+P E RPLPGRLNVVLTRSGSFDIAT ENV+ICGS+TSAL
Sbjct: 60   TTSDPGKRNAVLMGRKTWESLPAEHRPLPGRLNVVLTRSGSFDIATVENVIICGSITSAL 119

Query: 412  ELLAASPYCLSIEKVFVIGGGQILKEALNAPECDAVHITEISTSIECDTFMPPVDHSIYR 591
            ELLAASPYCLSIEKVFVIGGG+IL+EA+NAPECDAVHITEI T++ECDTF+P VD SI++
Sbjct: 120  ELLAASPYCLSIEKVFVIGGGEILREAMNAPECDAVHITEIETNVECDTFIPAVDKSIFQ 179

Query: 592  PWYSSFPLVENNILLSYVSYIRVRQSALESVTFNNGDISNGSNSVKLEVDKSSSLPKMIF 771
            PWYSSFP+VE N+  S+ SY+RVR SA   +  NNG +S+          K S LPK IF
Sbjct: 180  PWYSSFPVVEKNLRYSFNSYVRVRSSAEPPIDQNNGLVSHNKPDFSNFEAKFSFLPKEIF 239

Query: 772  EKHKEYMYLKLVQDIISNGIQKDDRTGTGTLSKFGCQMRFNLRKSFPLLTTKKVFWRGVV 951
            E+H+EY+YLKLVQ+IIS+GI KDDRTGTGTLSKFGCQMR+NLRK+FPLLTTKKVFWRGVV
Sbjct: 240  ERHEEYLYLKLVQEIISDGIPKDDRTGTGTLSKFGCQMRYNLRKTFPLLTTKKVFWRGVV 299

Query: 952  EELLWFISGSTNAKVLQEKGIRIWDGNASRDYLDSIGLTDREDGDLGPIYGFQWRH 1119
            EELLWFISGSTNAKVLQEKGI IWDGNASRDYLDSIGL +RE+GDLGP+YGFQWRH
Sbjct: 300  EELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLREREEGDLGPVYGFQWRH 355


>ref|NP_001238644.1| bifunctional dihydrofolate reductase-thymidylate synthase [Glycine
            max] gi|1706522|sp|P51820.1|DRTS_SOYBN RecName:
            Full=Bifunctional dihydrofolate reductase-thymidylate
            synthase; Short=DHFR-TS; Includes: RecName:
            Full=Dihydrofolate reductase; Includes: RecName:
            Full=Thymidylate synthase gi|999190|gb|AAB34317.1|
            dihydrofolate reductase-thymidylate synthase [Glycine
            max] gi|1096144|prf||2111237A dihydrofolate
            reductase-thymidylate synthase
          Length = 530

 Score =  546 bits (1408), Expect = e-153
 Identities = 269/345 (77%), Positives = 299/345 (86%), Gaps = 5/345 (1%)
 Frame = +1

Query: 100  NGSSNPL----RTYQVVVAATQTMGIGKDGKLPWNLPSDLKFFKEVTMVTSDPGKRNAVI 267
            NGS NPL    RTYQVVVAATQ  GIGKDGKLPW LP+DLKFFKE+TM TS+PGK+NA++
Sbjct: 14   NGSVNPLPNLQRTYQVVVAATQDWGIGKDGKLPWRLPTDLKFFKEITMKTSEPGKKNAIV 73

Query: 268  MGRKTWESIPPEKRPLPGRLNVVLTRSGSFDIATAENVVICGSMTSALELLAASPYCLSI 447
            MGRKTWESIP E RPL GRLNVVLTRSGSFDIATAENVVICGSM+SALELLAASPY LSI
Sbjct: 74   MGRKTWESIPLEYRPLSGRLNVVLTRSGSFDIATAENVVICGSMSSALELLAASPYSLSI 133

Query: 448  EKVFVIGGGQILKEALNAPECDAVHITEISTSIECDTFMPPVDHSIYRPWYSSFPLVENN 627
            EKVFVIGGGQI +EALN P C+A+H+TEI +SIECDTFMPPVD +I+RPWYSSFP VENN
Sbjct: 134  EKVFVIGGGQIFREALNVPGCEAIHLTEIQSSIECDTFMPPVDFTIFRPWYSSFPKVENN 193

Query: 628  ILLSYVSYIRVRQSALESVTFN-NGDISNGSNSVKLEVDKSSSLPKMIFEKHKEYMYLKL 804
            I  S+ +Y+RVR SA ES   N +  + N S S+K EV   S LPKMI E+H+EY+YLKL
Sbjct: 194  IRYSFTTYVRVRSSAAESAGQNIDPLLDNNSESMKFEVKDFSFLPKMISERHEEYLYLKL 253

Query: 805  VQDIISNGIQKDDRTGTGTLSKFGCQMRFNLRKSFPLLTTKKVFWRGVVEELLWFISGST 984
            VQDII+ G  K DRTGTGTLSKFGCQMRFNLR +FPLLTTKKVFWRGVVEELLWFISGST
Sbjct: 254  VQDIIAEGTTKGDRTGTGTLSKFGCQMRFNLRGNFPLLTTKKVFWRGVVEELLWFISGST 313

Query: 985  NAKVLQEKGIRIWDGNASRDYLDSIGLTDREDGDLGPIYGFQWRH 1119
            NAKVLQEKGI IWDGNASR+YLD +GLT+RE+GDLGP+YGFQWRH
Sbjct: 314  NAKVLQEKGIHIWDGNASREYLDGVGLTEREEGDLGPVYGFQWRH 358