BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Coptis25_contig00014977
         (1086 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

dbj|BAB62040.1| CjMDR1 [Coptis japonica]                              586   e-165
dbj|BAM11098.1| ABC protein [Coptis japonica]                         469   e-130
emb|CBI37062.3| unnamed protein product [Vitis vinifera]              412   e-113
ref|XP_002273987.1| PREDICTED: ABC transporter B family member 1...   412   e-113
ref|XP_002515185.1| multidrug resistance protein 1, 2, putative ...   410   e-112

>dbj|BAB62040.1| CjMDR1 [Coptis japonica]
          Length = 1289

 Score =  586 bits (1511), Expect = e-165
 Identities = 304/333 (91%), Positives = 306/333 (91%)
 Frame = +1

Query: 88   MAEENGLDGDLNNHQATASTSNSPVQGANGASETKGAQXXXXXXXXXXXIDQSVPYYKLL 267
            MAEENGLDGDLNNHQATASTSNSPVQGANG SETKGAQ           I QSVPYYKLL
Sbjct: 1    MAEENGLDGDLNNHQATASTSNSPVQGANGTSETKGAQEKSEKSKEEEKIGQSVPYYKLL 60

Query: 268  SFADSKDVLLMVIGTIAAVANGASMPVMTLLLGDLINAFGQNANNTDTLRVVSKVALKFV 447
            SFADSKDVLLMVIGTIAAVANGASMPVMTLLLGDLINAFGQNANNTDTLRVVSKVALKFV
Sbjct: 61   SFADSKDVLLMVIGTIAAVANGASMPVMTLLLGDLINAFGQNANNTDTLRVVSKVALKFV 120

Query: 448  YLSIGAGVASFFQVACWMVTGERQAARIRSLYLKTILRQDVAFFDKETNTGEVVGRMSGD 627
            YLSIGAGVASFFQVACWMVTGERQAARIRSLYLKTILRQDVAFFDKETNTGEVVGRMSGD
Sbjct: 121  YLSIGAGVASFFQVACWMVTGERQAARIRSLYLKTILRQDVAFFDKETNTGEVVGRMSGD 180

Query: 628  TVLIQDAIGEKVGKFIQLFSTFIGGFIIAFVKGWLLTLVMLTSIPPLVFCGALMTITISK 807
            TVLIQDAIGEKVGKFIQLFSTFIGGF+IAFVKGWLLTLVMLTSIPPLVFCGALMTITISK
Sbjct: 181  TVLIQDAIGEKVGKFIQLFSTFIGGFLIAFVKGWLLTLVMLTSIPPLVFCGALMTITISK 240

Query: 808  MASRGQVAYSQAGIVVEQTIGSIRTVASFTGEKHAVTQYEKYLNKAYLAGVHEXXXXXXX 987
            MASRGQVAYSQAGIVVEQTIGSIRTVASFTGEKHAVTQYEKYLNKAYLAG+HE       
Sbjct: 241  MASRGQVAYSQAGIVVEQTIGSIRTVASFTGEKHAVTQYEKYLNKAYLAGIHEGLASGVG 300

Query: 988  XXXXXXXIFCSYSLAVWFGGKMIIEKGYNGGNV 1086
                   IFCSYSLAVWFGGKMIIEKGYNGGNV
Sbjct: 301  LGSVLLVIFCSYSLAVWFGGKMIIEKGYNGGNV 333



 Score =  110 bits (276), Expect = 5e-22
 Identities = 70/274 (25%), Positives = 135/274 (49%), Gaps = 2/274 (0%)
 Frame = +1

Query: 241  QSVPYYKLLSFADSKDVLLMVIGTIAAVANGASMPVMTLLLGDLINAFGQNANNTDTLRV 420
            Q VP  +L +  +  ++ ++++G I+A+ NG   P+  +LL  +I  F +     D LR 
Sbjct: 706  QEVPLRRLATL-NKPEIPVLLLGVISAMVNGVIFPIFGVLLSSVIKTFYEPE---DKLRK 761

Query: 421  VSKV-ALKFVYLSIGAGVASFFQVACWMVTGERQAARIRSLYLKTILRQDVAFFDK-ETN 594
             ++  A  F+ L + + VA+      + V G R   RIRS+  +T+   ++ +FD+ E  
Sbjct: 762  DTRFWAFMFIILGVASFVAAPATAYFFAVAGCRLIQRIRSMCFRTVAHMEIDWFDEPEHA 821

Query: 595  TGEVVGRMSGDTVLIQDAIGEKVGKFIQLFSTFIGGFIIAFVKGWLLTLVMLTSIPPLVF 774
            +G +  ++S D   ++  +G+ +   +Q  +T + G +IAFV  W L L++L  IP +  
Sbjct: 822  SGAIGAKLSADASTVRGLVGDALALLVQNAATAVCGLVIAFVANWTLALIILVLIPLIGV 881

Query: 775  CGALMTITISKMASRGQVAYSQAGIVVEQTIGSIRTVASFTGEKHAVTQYEKYLNKAYLA 954
             G +    +   ++  ++ Y +A  V    +GSIRTVASF  E+  +  Y+K        
Sbjct: 882  NGYVQMKFMKGFSADAKMMYEEASQVANDAVGSIRTVASFCAEEKVMQLYKKKCEGPMKT 941

Query: 955  GVHEXXXXXXXXXXXXXXIFCSYSLAVWFGGKMI 1056
            G+ +              +F  Y+ + + G +++
Sbjct: 942  GIRQGLISGIGFGISFFLLFNVYATSFYAGARLV 975


>dbj|BAM11098.1| ABC protein [Coptis japonica]
          Length = 1292

 Score =  469 bits (1208), Expect = e-130
 Identities = 244/336 (72%), Positives = 276/336 (82%), Gaps = 3/336 (0%)
 Frame = +1

Query: 88   MAEENGLDGDLNNH-QATASTSNSPVQGANGAS-ETKGAQXXXXXXXXXXXID-QSVPYY 258
            MAEENG +GD NNH QATASTS+SP +  N  S  TK  Q           +  ++VPYY
Sbjct: 1    MAEENGFNGDQNNHLQATASTSHSPAKLTNKTSGSTKSDQQDSDKGEGVEKMSAETVPYY 60

Query: 259  KLLSFADSKDVLLMVIGTIAAVANGASMPVMTLLLGDLINAFGQNANNTDTLRVVSKVAL 438
            KL SFADSKD++LMVIGTIA+VANGASMP+MT L+GDLINAFGQNANN +TL VVS+VAL
Sbjct: 61   KLFSFADSKDLVLMVIGTIASVANGASMPIMTFLVGDLINAFGQNANNKNTLPVVSRVAL 120

Query: 439  KFVYLSIGAGVASFFQVACWMVTGERQAARIRSLYLKTILRQDVAFFDKETNTGEVVGRM 618
            +FVYL++GAGVAS FQVACWMVTGERQA+RIRSLYLKTILRQDVAFFDKETNTGEVVGRM
Sbjct: 121  RFVYLAVGAGVASVFQVACWMVTGERQASRIRSLYLKTILRQDVAFFDKETNTGEVVGRM 180

Query: 619  SGDTVLIQDAIGEKVGKFIQLFSTFIGGFIIAFVKGWLLTLVMLTSIPPLVFCGALMTIT 798
            SGD V IQDA+GEKVGKFIQLFSTFIGGFI+AFV+GWLLTL+ML+SIP LV  GA +TI 
Sbjct: 181  SGDIVRIQDAMGEKVGKFIQLFSTFIGGFIVAFVRGWLLTLIMLSSIPVLVISGAFVTIV 240

Query: 799  ISKMASRGQVAYSQAGIVVEQTIGSIRTVASFTGEKHAVTQYEKYLNKAYLAGVHEXXXX 978
            +SKMASRGQ AYSQA I VEQTIGSIRTVASF+GEKHA+TQYEK L KAY +GVHE    
Sbjct: 241  VSKMASRGQAAYSQAAITVEQTIGSIRTVASFSGEKHAITQYEKSLQKAYKSGVHEGLAS 300

Query: 979  XXXXXXXXXXIFCSYSLAVWFGGKMIIEKGYNGGNV 1086
                       FCSY+LA+WFGG+MIIEK Y GG++
Sbjct: 301  GLGLGASMLIFFCSYALAIWFGGRMIIEKDYTGGDI 336



 Score =  114 bits (284), Expect = 5e-23
 Identities = 72/274 (26%), Positives = 137/274 (50%), Gaps = 2/274 (0%)
 Frame = +1

Query: 241  QSVPYYKLLSFADSKDVLLMVIGTIAAVANGASMPVMTLLLGDLINAFGQNANNTDTLRV 420
            + VP  +L S  +  ++ ++++G I+A  NG   P+  +LL  +I  F +     D LR 
Sbjct: 709  EEVPLLRLASL-NKPEIPILLLGAISAAINGLIFPIFGVLLASVIKTFYKPE---DELRK 764

Query: 421  VSKV-ALKFVYLSIGAGVASFFQVACWMVTGERQAARIRSLYLKTILRQDVAFFDK-ETN 594
             S+  AL F+ L I + VAS      + V G R   RIRS+  + ++  ++ +FD+ E +
Sbjct: 765  DSRFWALMFIVLGIASFVASPAGTYFFSVAGCRLIQRIRSMCFEKVVHMEINWFDEPEHS 824

Query: 595  TGEVVGRMSGDTVLIQDAIGEKVGKFIQLFSTFIGGFIIAFVKGWLLTLVMLTSIPPLVF 774
            +G +  ++S D   ++  +G+ +   +Q  ++ I G  IAF   W+L L++L  +P +  
Sbjct: 825  SGAIGAKLSSDAASVRSLVGDALSLLVQNAASAIAGLAIAFEANWILALIILVLLPLIGL 884

Query: 775  CGALMTITISKMASRGQVAYSQAGIVVEQTIGSIRTVASFTGEKHAVTQYEKYLNKAYLA 954
             G L T  ++  ++  ++ Y +A  V    +GSIRTVASF  E+  +  Y+K        
Sbjct: 885  NGYLQTKFMTGFSADAKMMYEEASQVASDAVGSIRTVASFCAEEKVMQLYKKKCEGPMKT 944

Query: 955  GVHEXXXXXXXXXXXXXXIFCSYSLAVWFGGKMI 1056
            G+ +              ++  Y+ + + G +++
Sbjct: 945  GIRQGLISGIGFGVSFFLLYNVYATSFYVGARLV 978


>emb|CBI37062.3| unnamed protein product [Vitis vinifera]
          Length = 1147

 Score =  412 bits (1060), Expect = e-113
 Identities = 215/333 (64%), Positives = 252/333 (75%)
 Frame = +1

Query: 88   MAEENGLDGDLNNHQATASTSNSPVQGANGASETKGAQXXXXXXXXXXXIDQSVPYYKLL 267
            MAEEN L+G    H+AT S+  +       +S   G Q              +VP++KL 
Sbjct: 1    MAEENDLNGKTYMHEATTSSRGALETETVKSSGQNGKQQDSEKSKEEGK-PSTVPFHKLF 59

Query: 268  SFADSKDVLLMVIGTIAAVANGASMPVMTLLLGDLINAFGQNANNTDTLRVVSKVALKFV 447
            SFADS D+LLM+ GTI A  NG  MP+M +L GDLI++FGQN NN D + +VSKV+LKFV
Sbjct: 60   SFADSTDMLLMITGTIGAAGNGICMPLMAILFGDLIDSFGQNQNNKDVVDIVSKVSLKFV 119

Query: 448  YLSIGAGVASFFQVACWMVTGERQAARIRSLYLKTILRQDVAFFDKETNTGEVVGRMSGD 627
            YL++GAG+A+FFQVACWMVTGERQAARIRSLYLKTILRQDVAFFDKETNTGEV+GRMSGD
Sbjct: 120  YLAVGAGIAAFFQVACWMVTGERQAARIRSLYLKTILRQDVAFFDKETNTGEVIGRMSGD 179

Query: 628  TVLIQDAIGEKVGKFIQLFSTFIGGFIIAFVKGWLLTLVMLTSIPPLVFCGALMTITISK 807
            TVLIQDA+GEKVGKFIQL STFIGGFIIAF+KGWLLTLVML+SIP LV  G  M++ +SK
Sbjct: 180  TVLIQDAMGEKVGKFIQLVSTFIGGFIIAFIKGWLLTLVMLSSIPLLVIAGGAMSLFLSK 239

Query: 808  MASRGQVAYSQAGIVVEQTIGSIRTVASFTGEKHAVTQYEKYLNKAYLAGVHEXXXXXXX 987
            MA+RGQ AY++A  VVEQTIGSIRTVASFTGEK AVT+Y ++L  AY +GV E       
Sbjct: 240  MATRGQNAYAKAATVVEQTIGSIRTVASFTGEKQAVTKYNQFLVNAYKSGVFEGLAAGLG 299

Query: 988  XXXXXXXIFCSYSLAVWFGGKMIIEKGYNGGNV 1086
                   IF SY+LAVWFG KMI+EKGY GG V
Sbjct: 300  LGTVMFIIFASYALAVWFGAKMILEKGYTGGTV 332



 Score = 69.3 bits (168), Expect = 2e-09
 Identities = 46/208 (22%), Positives = 88/208 (42%)
 Frame = +1

Query: 433  ALKFVYLSIGAGVASFFQVACWMVTGERQAARIRSLYLKTILRQDVAFFDKETNTGEVVG 612
            AL F+ L + + +A   +   + V G +   R+RS+  + ++  +VA             
Sbjct: 675  ALIFLVLGVVSFLAFPARTYLFSVAGCKLIQRVRSMCFEKVVHMEVAL------------ 722

Query: 613  RMSGDTVLIQDAIGEKVGKFIQLFSTFIGGFIIAFVKGWLLTLVMLTSIPPLVFCGALMT 792
                        +G+ + + +Q  ++ I G  IAF   W L  ++L  IP +   G +  
Sbjct: 723  ------------VGDALAQVVQNAASAIAGLAIAFAASWQLAFIILALIPLIGLNGYVQI 770

Query: 793  ITISKMASRGQVAYSQAGIVVEQTIGSIRTVASFTGEKHAVTQYEKYLNKAYLAGVHEXX 972
              +   ++  ++ Y +A  V    +GSIRTVASF  E+  +  Y+K        G+ +  
Sbjct: 771  KFLKGFSADAKMMYEEASQVANDAVGSIRTVASFCAEEKVMDLYKKKCEGPMRTGIRQGL 830

Query: 973  XXXXXXXXXXXXIFCSYSLAVWFGGKMI 1056
                        +FC Y+L  + G +++
Sbjct: 831  VSGIGFGVSFFLLFCVYALCFYAGARLV 858


>ref|XP_002273987.1| PREDICTED: ABC transporter B family member 11 [Vitis vinifera]
          Length = 1297

 Score =  412 bits (1060), Expect = e-113
 Identities = 215/333 (64%), Positives = 252/333 (75%)
 Frame = +1

Query: 88   MAEENGLDGDLNNHQATASTSNSPVQGANGASETKGAQXXXXXXXXXXXIDQSVPYYKLL 267
            MAEEN L+G    H+AT S+  +       +S   G Q              +VP++KL 
Sbjct: 1    MAEENDLNGKTYMHEATTSSRGALETETVKSSGQNGKQQDSEKSKEEGK-PSTVPFHKLF 59

Query: 268  SFADSKDVLLMVIGTIAAVANGASMPVMTLLLGDLINAFGQNANNTDTLRVVSKVALKFV 447
            SFADS D+LLM+ GTI A  NG  MP+M +L GDLI++FGQN NN D + +VSKV+LKFV
Sbjct: 60   SFADSTDMLLMITGTIGAAGNGICMPLMAILFGDLIDSFGQNQNNKDVVDIVSKVSLKFV 119

Query: 448  YLSIGAGVASFFQVACWMVTGERQAARIRSLYLKTILRQDVAFFDKETNTGEVVGRMSGD 627
            YL++GAG+A+FFQVACWMVTGERQAARIRSLYLKTILRQDVAFFDKETNTGEV+GRMSGD
Sbjct: 120  YLAVGAGIAAFFQVACWMVTGERQAARIRSLYLKTILRQDVAFFDKETNTGEVIGRMSGD 179

Query: 628  TVLIQDAIGEKVGKFIQLFSTFIGGFIIAFVKGWLLTLVMLTSIPPLVFCGALMTITISK 807
            TVLIQDA+GEKVGKFIQL STFIGGFIIAF+KGWLLTLVML+SIP LV  G  M++ +SK
Sbjct: 180  TVLIQDAMGEKVGKFIQLVSTFIGGFIIAFIKGWLLTLVMLSSIPLLVIAGGAMSLFLSK 239

Query: 808  MASRGQVAYSQAGIVVEQTIGSIRTVASFTGEKHAVTQYEKYLNKAYLAGVHEXXXXXXX 987
            MA+RGQ AY++A  VVEQTIGSIRTVASFTGEK AVT+Y ++L  AY +GV E       
Sbjct: 240  MATRGQNAYAKAATVVEQTIGSIRTVASFTGEKQAVTKYNQFLVNAYKSGVFEGLAAGLG 299

Query: 988  XXXXXXXIFCSYSLAVWFGGKMIIEKGYNGGNV 1086
                   IF SY+LAVWFG KMI+EKGY GG V
Sbjct: 300  LGTVMFIIFASYALAVWFGAKMILEKGYTGGTV 332



 Score =  114 bits (286), Expect = 3e-23
 Identities = 67/266 (25%), Positives = 134/266 (50%), Gaps = 2/266 (0%)
 Frame = +1

Query: 265  LSFADSKDVLLMVIGTIAAVANGASMPVMTLLLGDLINAFGQNANNTDTLRVVSKV-ALK 441
            L++ +  ++ ++++GT+AA+ NG  +P+  +L+  +I  F +  +    LR  S   AL 
Sbjct: 720  LAYLNKPEIPVLLLGTVAAIVNGTILPIFGILISSVIKTFYEPPHQ---LRKDSNFWALI 776

Query: 442  FVYLSIGAGVASFFQVACWMVTGERQAARIRSLYLKTILRQDVAFFDK-ETNTGEVVGRM 618
            F+ L + + +A   +   + V G +   R+RS+  + ++  +V +FD+ E ++G +  R+
Sbjct: 777  FLVLGVVSFLAFPARTYLFSVAGCKLIQRVRSMCFEKVVHMEVGWFDQPEHSSGAIGARL 836

Query: 619  SGDTVLIQDAIGEKVGKFIQLFSTFIGGFIIAFVKGWLLTLVMLTSIPPLVFCGALMTIT 798
            S D   I+  +G+ + + +Q  ++ I G  IAF   W L  ++L  IP +   G +    
Sbjct: 837  SADAATIRALVGDALAQVVQNAASAIAGLAIAFAASWQLAFIILALIPLIGLNGYVQIKF 896

Query: 799  ISKMASRGQVAYSQAGIVVEQTIGSIRTVASFTGEKHAVTQYEKYLNKAYLAGVHEXXXX 978
            +   ++  ++ Y +A  V    +GSIRTVASF  E+  +  Y+K        G+ +    
Sbjct: 897  LKGFSADAKMMYEEASQVANDAVGSIRTVASFCAEEKVMDLYKKKCEGPMRTGIRQGLVS 956

Query: 979  XXXXXXXXXXIFCSYSLAVWFGGKMI 1056
                      +FC Y+L  + G +++
Sbjct: 957  GIGFGVSFFLLFCVYALCFYAGARLV 982


>ref|XP_002515185.1| multidrug resistance protein 1, 2, putative [Ricinus communis]
            gi|223545665|gb|EEF47169.1| multidrug resistance protein
            1, 2, putative [Ricinus communis]
          Length = 1292

 Score =  410 bits (1053), Expect = e-112
 Identities = 213/340 (62%), Positives = 252/340 (74%), Gaps = 7/340 (2%)
 Frame = +1

Query: 88   MAEENGLDGDLNNHQATASTS---NSPVQGANG----ASETKGAQXXXXXXXXXXXIDQS 246
            MA ENG+  D + H+ + S           ANG      ++KG +              S
Sbjct: 1    MAVENGIHSDTSTHETSTSKGLEEKDKSARANGHPQEIEKSKGEEKT-----------NS 49

Query: 247  VPYYKLLSFADSKDVLLMVIGTIAAVANGASMPVMTLLLGDLINAFGQNANNTDTLRVVS 426
            VP++KL SFADS D++LM+IGTI A+ NG SMP+MT+ LGD I+AFG N NN D + VVS
Sbjct: 50   VPFHKLFSFADSVDIVLMIIGTIGALGNGLSMPLMTIFLGDTIDAFGNNQNNQDVVDVVS 109

Query: 427  KVALKFVYLSIGAGVASFFQVACWMVTGERQAARIRSLYLKTILRQDVAFFDKETNTGEV 606
            KV+LKFVYL IG+ VASF QV CWMVTGERQAARIR LYLKTILRQD+AFFDKETNTGEV
Sbjct: 110  KVSLKFVYLGIGSSVASFLQVVCWMVTGERQAARIRGLYLKTILRQDIAFFDKETNTGEV 169

Query: 607  VGRMSGDTVLIQDAIGEKVGKFIQLFSTFIGGFIIAFVKGWLLTLVMLTSIPPLVFCGAL 786
            +GRMSGDTVLIQDA+GEKVGKF+QL STF+GGF+IAFVKGWLLTLVML+S+P LV  GA 
Sbjct: 170  IGRMSGDTVLIQDAMGEKVGKFLQLVSTFLGGFVIAFVKGWLLTLVMLSSLPLLVLAGAA 229

Query: 787  MTITISKMASRGQVAYSQAGIVVEQTIGSIRTVASFTGEKHAVTQYEKYLNKAYLAGVHE 966
            M+I I+K+ASRGQ AY++A  VVEQTIGSIRTVASFTGEK A+  YEK+L  AY +G HE
Sbjct: 230  MSIMIAKIASRGQNAYAKAATVVEQTIGSIRTVASFTGEKQAIRNYEKFLLAAYHSGAHE 289

Query: 967  XXXXXXXXXXXXXXIFCSYSLAVWFGGKMIIEKGYNGGNV 1086
                          +FCSY+LA+WFGGKMI+EKGY GG V
Sbjct: 290  GLITGLGLGLFMLILFCSYALAIWFGGKMILEKGYTGGEV 329



 Score =  110 bits (275), Expect = 6e-22
 Identities = 64/266 (24%), Positives = 131/266 (49%), Gaps = 2/266 (0%)
 Frame = +1

Query: 265  LSFADSKDVLLMVIGTIAAVANGASMPVMTLLLGDLINAFGQNANNTDTLRVVSKV-ALK 441
            L++ +  ++ +++ G+IAA+ NG   P+  +L+  +I +F +  +    LR  SK  A+ 
Sbjct: 714  LAYLNKPEIPVLIAGSIAAIINGVVFPLFGILISRVIESFFKPPHE---LRKDSKFWAII 770

Query: 442  FVYLSIGAGVASFFQVACWMVTGERQAARIRSLYLKTILRQDVAFFD-KETNTGEVVGRM 618
            FV +++ + +A   Q+  + V G +   RIRS+    ++  +V +FD  E ++G +  R+
Sbjct: 771  FVIVAVVSSLACIAQLYFFAVAGSKLIQRIRSMCFDKVVHMEVGWFDVPEHSSGAIGARL 830

Query: 619  SGDTVLIQDAIGEKVGKFIQLFSTFIGGFIIAFVKGWLLTLVMLTSIPPLVFCGALMTIT 798
            S D   ++  +G+ + + +Q  ++ + G IIAF   W L  ++L  +P       +    
Sbjct: 831  SADAAAVRSLVGDSLAQMVQNIASAVAGLIIAFTSSWQLAFIILVIVPLTGLNAYVQLKF 890

Query: 799  ISKMASRGQVAYSQAGIVVEQTIGSIRTVASFTGEKHAVTQYEKYLNKAYLAGVHEXXXX 978
            +   ++  ++ Y +A  V    +GSIRTVASF  E+  +  Y K        G+ +    
Sbjct: 891  LRGFSADAKMMYEEASQVANDAVGSIRTVASFCAEEKVMQLYRKKCEGPLKTGIRQGLIS 950

Query: 979  XXXXXXXXXXIFCSYSLAVWFGGKMI 1056
                      +F  Y+ + + G +++
Sbjct: 951  GIGFGVSFFLLFSVYATSFYAGAQLV 976