BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Coptis25_contig00012440
         (1939 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002284060.1| PREDICTED: uncharacterized protein LOC100264...   932   0.0  
emb|CAN82225.1| hypothetical protein VITISV_011873 [Vitis vinifera]   931   0.0  
ref|XP_004136618.1| PREDICTED: uncharacterized protein LOC101214...   928   0.0  
ref|XP_003535921.1| PREDICTED: uncharacterized protein LOC100805...   918   0.0  
ref|XP_003519071.1| PREDICTED: uncharacterized protein LOC100786...   912   0.0  

>ref|XP_002284060.1| PREDICTED: uncharacterized protein LOC100264133 [Vitis vinifera]
          Length = 762

 Score =  932 bits (2410), Expect = 0.0
 Identities = 450/572 (78%), Positives = 510/572 (89%), Gaps = 3/572 (0%)
 Frame = +2

Query: 230  MFVQDRF---SPKPQIRPLPQLHPDRLHPSTKSLDFSSWLSENFYKIIAISLLIVSVAGI 400
            M VQDR    SPK  IR L  LHPDR     K+LDFS+W SEN YKI+ ISLLI +VA +
Sbjct: 1    MLVQDRSTPKSPKTHIRALHSLHPDRF-TEPKNLDFSTWFSENLYKIVTISLLIATVAAL 59

Query: 401  FFLKNVGSSGALMCLQTRAIELERIAFPKVEWNLIKPIVDKTSPYASFQSKRWIVVSVSN 580
            FFL+NV  + AL+  +T+A  LE+I FP++ WN +  + DK SPYA+F+S+RWI+VSVSN
Sbjct: 60   FFLRNVADTAALVSYETQAKSLEKIEFPQINWNSVALVSDK-SPYANFRSERWILVSVSN 118

Query: 581  YPSNSLRKLVKIKGWQVLAIGNSKTPSDWNLKGAIFLSLDQQASLNFRVVDHLPYDSYVR 760
            YP++SLRKLVKIKGWQVLAIGNSKTPSDW+LKGAIFLSL+QQA+L FRVVDHLPYDS+VR
Sbjct: 119  YPTDSLRKLVKIKGWQVLAIGNSKTPSDWSLKGAIFLSLEQQANLGFRVVDHLPYDSFVR 178

Query: 761  KSVGYLFAIQHGAKKIFDADDRGEVIDGDLGKHFDLELIGEKARRQPIMQYSHENPNKTV 940
            K+VGYLFAIQHGAKKIFDADDRG+VID DLGKHFD+ELIGE AR+  I+QYSHENPN+T+
Sbjct: 179  KNVGYLFAIQHGAKKIFDADDRGDVIDNDLGKHFDVELIGEGARQDIILQYSHENPNRTI 238

Query: 941  VNPYIHFGQRSVWPRGLPLENVGEVGHEEFYTELYGGKQLIQQGISNGLPDVDSVFYFTR 1120
            VNPYIHFGQRSVWPRGLPLENVGE+GHEEFYTE++GGKQ IQQGISNGLPDVDSVFYFTR
Sbjct: 239  VNPYIHFGQRSVWPRGLPLENVGEIGHEEFYTEVFGGKQFIQQGISNGLPDVDSVFYFTR 298

Query: 1121 KSSLEMFDIQFDEHAPKVALPQGMMVPMNSFNTLFHASAFWALMLPVSVSTMASDVLRGY 1300
            K  LE FDI+FDEHAPKVALPQG MVP+NSFNTL+H+SAFWALMLPVSVSTMASDVLRGY
Sbjct: 299  KPGLEAFDIRFDEHAPKVALPQGTMVPVNSFNTLYHSSAFWALMLPVSVSTMASDVLRGY 358

Query: 1301 WGQRLLWEIGGHVVVYPPTVHRFDSIQSYPFSEEKDLHVNVGRLIKFLVQWRSGKHRLFE 1480
            WGQRLLWEIGG+VVVYPPTVHR+D I+SYPFSEEKDLHVNVGRL+KFLV WRS KHRLFE
Sbjct: 359  WGQRLLWEIGGYVVVYPPTVHRYDRIESYPFSEEKDLHVNVGRLLKFLVSWRSSKHRLFE 418

Query: 1481 KIMQLSYAMAEEGFWTELDVKFTADWLQDLLAVGYQQPRLMTLELGRPRATIGHGDRKEF 1660
            KI++LSY MAEEGFWTE DVKFTA WLQDLLAVGYQQPRLM+LEL RPRA+IGHGDRKEF
Sbjct: 419  KILELSYVMAEEGFWTEKDVKFTAAWLQDLLAVGYQQPRLMSLELDRPRASIGHGDRKEF 478

Query: 1661 VPQKLPSVHLGVKEVGTVNYEIGNLIQWRKNFGNVVLILFCTSPVERTALEWRLLYGRIF 1840
            +PQKLPSVHLGV+E G VN EIG+LI+WRKNFGNVVLI+FC+ PVERTALEWRLLYGRIF
Sbjct: 479  IPQKLPSVHLGVEETGVVNNEIGSLIRWRKNFGNVVLIMFCSGPVERTALEWRLLYGRIF 538

Query: 1841 KTVIILSEQSNSELAVERGQLEQAYKYLPKIF 1936
            +TV+IL+EQ N++LAVE G+L+  YK L  IF
Sbjct: 539  RTVVILAEQKNADLAVEEGRLDFVYKQLLNIF 570


>emb|CAN82225.1| hypothetical protein VITISV_011873 [Vitis vinifera]
          Length = 762

 Score =  931 bits (2407), Expect = 0.0
 Identities = 449/572 (78%), Positives = 510/572 (89%), Gaps = 3/572 (0%)
 Frame = +2

Query: 230  MFVQDRF---SPKPQIRPLPQLHPDRLHPSTKSLDFSSWLSENFYKIIAISLLIVSVAGI 400
            M VQDR    SPK  IR L  LHPDR     K+LDFS+W SEN YKI+ ISLLI +VA +
Sbjct: 1    MLVQDRSTPKSPKTHIRALHSLHPDRF-TEPKNLDFSTWFSENLYKIVTISLLIATVAAL 59

Query: 401  FFLKNVGSSGALMCLQTRAIELERIAFPKVEWNLIKPIVDKTSPYASFQSKRWIVVSVSN 580
            FFL+NV  + AL+  +T+A  LE+I FP++ WN +  + DK SPYA+F+S+RWI+VSVSN
Sbjct: 60   FFLRNVADTAALVSYETQAKSLEKIEFPQINWNSVALVSDK-SPYANFRSERWILVSVSN 118

Query: 581  YPSNSLRKLVKIKGWQVLAIGNSKTPSDWNLKGAIFLSLDQQASLNFRVVDHLPYDSYVR 760
            YP++SLRKLVKIKGWQVLAIGNSKTPSDW+LKGAIFLSL+QQA+L FRVVDHLPYDS+VR
Sbjct: 119  YPTDSLRKLVKIKGWQVLAIGNSKTPSDWSLKGAIFLSLEQQANLGFRVVDHLPYDSFVR 178

Query: 761  KSVGYLFAIQHGAKKIFDADDRGEVIDGDLGKHFDLELIGEKARRQPIMQYSHENPNKTV 940
            K+VGYLFAIQHGAKKIFDADDRG+VID DLGKHFD+ELIGE AR+  I+QYSHENPN+T+
Sbjct: 179  KNVGYLFAIQHGAKKIFDADDRGDVIDNDLGKHFDVELIGEGARQDIILQYSHENPNRTI 238

Query: 941  VNPYIHFGQRSVWPRGLPLENVGEVGHEEFYTELYGGKQLIQQGISNGLPDVDSVFYFTR 1120
            VNPYIHFGQRSVWPRGLPLENVGE+GHEEFYTE++GGKQ IQQGISNGLPDVDSVFYFTR
Sbjct: 239  VNPYIHFGQRSVWPRGLPLENVGEIGHEEFYTEVFGGKQFIQQGISNGLPDVDSVFYFTR 298

Query: 1121 KSSLEMFDIQFDEHAPKVALPQGMMVPMNSFNTLFHASAFWALMLPVSVSTMASDVLRGY 1300
            K  LE FDI+FDEHAPKVALPQG MVP+N+FNTL+H+SAFWALMLPVSVSTMASDVLRGY
Sbjct: 299  KPGLEAFDIRFDEHAPKVALPQGTMVPVNTFNTLYHSSAFWALMLPVSVSTMASDVLRGY 358

Query: 1301 WGQRLLWEIGGHVVVYPPTVHRFDSIQSYPFSEEKDLHVNVGRLIKFLVQWRSGKHRLFE 1480
            WGQRLLWEIGG+VVVYPPTVHR+D I+SYPFSEEKDLHVNVGRL+KFLV WRS KHRLFE
Sbjct: 359  WGQRLLWEIGGYVVVYPPTVHRYDRIESYPFSEEKDLHVNVGRLLKFLVSWRSSKHRLFE 418

Query: 1481 KIMQLSYAMAEEGFWTELDVKFTADWLQDLLAVGYQQPRLMTLELGRPRATIGHGDRKEF 1660
            KI++LSY MAEEGFWTE DVKFTA WLQDLLAVGYQQPRLM+LEL RPRA+IGHGDRKEF
Sbjct: 419  KILELSYVMAEEGFWTEKDVKFTAAWLQDLLAVGYQQPRLMSLELDRPRASIGHGDRKEF 478

Query: 1661 VPQKLPSVHLGVKEVGTVNYEIGNLIQWRKNFGNVVLILFCTSPVERTALEWRLLYGRIF 1840
            +PQKLPSVHLGV+E G VN EIG+LI+WRKNFGNVVLI+FC+ PVERTALEWRLLYGRIF
Sbjct: 479  IPQKLPSVHLGVEETGVVNNEIGSLIRWRKNFGNVVLIMFCSGPVERTALEWRLLYGRIF 538

Query: 1841 KTVIILSEQSNSELAVERGQLEQAYKYLPKIF 1936
            +TV+IL+EQ N++LAVE G+L+  YK L  IF
Sbjct: 539  RTVVILAEQKNADLAVEEGRLDFVYKQLLNIF 570


>ref|XP_004136618.1| PREDICTED: uncharacterized protein LOC101214137 [Cucumis sativus]
            gi|449523175|ref|XP_004168600.1| PREDICTED:
            uncharacterized protein LOC101224948 [Cucumis sativus]
          Length = 762

 Score =  928 bits (2398), Expect = 0.0
 Identities = 443/573 (77%), Positives = 509/573 (88%), Gaps = 3/573 (0%)
 Frame = +2

Query: 230  MFVQDRF---SPKPQIRPLPQLHPDRLHPSTKSLDFSSWLSENFYKIIAISLLIVSVAGI 400
            M VQ+R    SPK QIR LP LH  R   S KSLDFS+WLS+N Y+++ I LLIV+VA +
Sbjct: 1    MLVQERSTPKSPKTQIRTLPTLHSHRFSES-KSLDFSTWLSDNVYRVVTILLLIVTVAAL 59

Query: 401  FFLKNVGSSGALMCLQTRAIELERIAFPKVEWNLIKPIVDKTSPYASFQSKRWIVVSVSN 580
            FFL+NVG S AL+C Q++   LE+I FPK++WN I  I   ++ Y  F+S++WIVVSVSN
Sbjct: 60   FFLRNVGDSAALLCFQSQTAALEKIQFPKIDWNSIASIPASSNLYPEFRSEQWIVVSVSN 119

Query: 581  YPSNSLRKLVKIKGWQVLAIGNSKTPSDWNLKGAIFLSLDQQASLNFRVVDHLPYDSYVR 760
            YPS+SLRKLVK+KGWQVLAIGNS TP+DW LKGAI+LSLD+Q+ L FRVV++LPYDS+VR
Sbjct: 120  YPSDSLRKLVKMKGWQVLAIGNSLTPADWALKGAIYLSLDEQSKLGFRVVEYLPYDSFVR 179

Query: 761  KSVGYLFAIQHGAKKIFDADDRGEVIDGDLGKHFDLELIGEKARRQPIMQYSHENPNKTV 940
            K+VGYLFAIQHGAKKIFD DDRGEVIDGDLGKHFD++L+GE AR++ I+QYSHENPN+TV
Sbjct: 180  KTVGYLFAIQHGAKKIFDVDDRGEVIDGDLGKHFDVQLVGEGARQEIILQYSHENPNRTV 239

Query: 941  VNPYIHFGQRSVWPRGLPLENVGEVGHEEFYTELYGGKQLIQQGISNGLPDVDSVFYFTR 1120
            VNPYIHFGQRSVWPRGLPLENVGE+ HEEFYTE++GGKQ IQQGISNGLPDVDSVFYFTR
Sbjct: 240  VNPYIHFGQRSVWPRGLPLENVGELAHEEFYTEIFGGKQFIQQGISNGLPDVDSVFYFTR 299

Query: 1121 KSSLEMFDIQFDEHAPKVALPQGMMVPMNSFNTLFHASAFWALMLPVSVSTMASDVLRGY 1300
            KS LE FDI+FDE APKVALPQGMMVP+NSFNTL+H SAFWALMLPVS+STMASDVLRGY
Sbjct: 300  KSGLEAFDIRFDERAPKVALPQGMMVPINSFNTLYHTSAFWALMLPVSISTMASDVLRGY 359

Query: 1301 WGQRLLWEIGGHVVVYPPTVHRFDSIQSYPFSEEKDLHVNVGRLIKFLVQWRSGKHRLFE 1480
            WGQRLLWEIGG+VVVYPPT+HR+D I++YPFSEE+DLHVNVGRL+KFL  WRS KHRLFE
Sbjct: 360  WGQRLLWEIGGYVVVYPPTIHRYDKIEAYPFSEERDLHVNVGRLVKFLNSWRSSKHRLFE 419

Query: 1481 KIMQLSYAMAEEGFWTELDVKFTADWLQDLLAVGYQQPRLMTLELGRPRATIGHGDRKEF 1660
            KI++LS+ MAEEGFWTE DVKFTA WLQDL+AVGYQQPRLM+LEL RPRATIG GDRKEF
Sbjct: 420  KILELSFVMAEEGFWTEKDVKFTAAWLQDLIAVGYQQPRLMSLELDRPRATIGDGDRKEF 479

Query: 1661 VPQKLPSVHLGVKEVGTVNYEIGNLIQWRKNFGNVVLILFCTSPVERTALEWRLLYGRIF 1840
            VPQKLPS+HLGV+E GTV+YEIGNLI+WRK FGNVVLI+FC SPVERTALEWRLLYGRIF
Sbjct: 480  VPQKLPSIHLGVEETGTVSYEIGNLIRWRKFFGNVVLIMFCNSPVERTALEWRLLYGRIF 539

Query: 1841 KTVIILSEQSNSELAVERGQLEQAYKYLPKIFD 1939
            KTVIILSE  N++L VE G+L+ AYKYLPK+FD
Sbjct: 540  KTVIILSETKNADLVVEEGRLDHAYKYLPKVFD 572


>ref|XP_003535921.1| PREDICTED: uncharacterized protein LOC100805551 [Glycine max]
          Length = 759

 Score =  918 bits (2372), Expect = 0.0
 Identities = 430/570 (75%), Positives = 506/570 (88%)
 Frame = +2

Query: 230  MFVQDRFSPKPQIRPLPQLHPDRLHPSTKSLDFSSWLSENFYKIIAISLLIVSVAGIFFL 409
            M VQ+R  PK  +   P      L  STKSLDFS+W+S+N  +I+A+ LL+ +VA +FFL
Sbjct: 1    MMVQERSLPK-SVNSKPHARTAAL-ASTKSLDFSAWVSDNLVRIVAVVLLVATVAAVFFL 58

Query: 410  KNVGSSGALMCLQTRAIELERIAFPKVEWNLIKPIVDKTSPYASFQSKRWIVVSVSNYPS 589
            +N G + AL+C + +A ELERIA+P+V+W+ I PI D+TS ++SF+S++WIVVSVS YPS
Sbjct: 59   RNAGDTAALLCFENQARELERIAYPRVDWSAIAPIADRTSKFSSFRSEKWIVVSVSGYPS 118

Query: 590  NSLRKLVKIKGWQVLAIGNSKTPSDWNLKGAIFLSLDQQASLNFRVVDHLPYDSYVRKSV 769
            ++LR+LVK+KGWQV+A+G S TPSDW LKGAIFLSL++Q +L FRVVD+LPYDS+VRKSV
Sbjct: 119  DALRRLVKMKGWQVVAVGGSNTPSDWTLKGAIFLSLEEQVNLGFRVVDYLPYDSFVRKSV 178

Query: 770  GYLFAIQHGAKKIFDADDRGEVIDGDLGKHFDLELIGEKARRQPIMQYSHENPNKTVVNP 949
            GYLFAIQHGAKKIFDADDRGEVIDGDLGKHFD+EL+GE AR++ ++QYSH+NPN+TVVNP
Sbjct: 179  GYLFAIQHGAKKIFDADDRGEVIDGDLGKHFDVELVGEAARQEVLLQYSHDNPNRTVVNP 238

Query: 950  YIHFGQRSVWPRGLPLENVGEVGHEEFYTELYGGKQLIQQGISNGLPDVDSVFYFTRKSS 1129
            Y+HFGQRSVWPRGLPLENVGE+GHEEFYT+++GGKQ IQQGISNGLPDVDSVFYFTRKS 
Sbjct: 239  YVHFGQRSVWPRGLPLENVGEIGHEEFYTQVFGGKQFIQQGISNGLPDVDSVFYFTRKSG 298

Query: 1130 LEMFDIQFDEHAPKVALPQGMMVPMNSFNTLFHASAFWALMLPVSVSTMASDVLRGYWGQ 1309
            LE FDIQFDEHAPKVALPQGMMVP+NSFNT++H+ AFWALMLPVSVSTMASDVLRGYWGQ
Sbjct: 299  LEAFDIQFDEHAPKVALPQGMMVPVNSFNTMYHSPAFWALMLPVSVSTMASDVLRGYWGQ 358

Query: 1310 RLLWEIGGHVVVYPPTVHRFDSIQSYPFSEEKDLHVNVGRLIKFLVQWRSGKHRLFEKIM 1489
            RLLWE+GG+VVVYPPTVHR+D I++YPFSEEKDLHVNVGRLI +L+ WRS KHRLFEKI+
Sbjct: 359  RLLWEVGGYVVVYPPTVHRYDRIEAYPFSEEKDLHVNVGRLINYLISWRSDKHRLFEKIL 418

Query: 1490 QLSYAMAEEGFWTELDVKFTADWLQDLLAVGYQQPRLMTLELGRPRATIGHGDRKEFVPQ 1669
             LS+AMAEEGFWTE DVK TA WLQDLLAVGYQQPRLM+LELGRPRA IGHGD+KEFVPQ
Sbjct: 419  DLSFAMAEEGFWTEKDVKLTAAWLQDLLAVGYQQPRLMSLELGRPRANIGHGDQKEFVPQ 478

Query: 1670 KLPSVHLGVKEVGTVNYEIGNLIQWRKNFGNVVLILFCTSPVERTALEWRLLYGRIFKTV 1849
            KLPSVHLGV+E GTVNYEI NLI WRK FGNVVLI++C  PVERTALEWRLLYGRIF++V
Sbjct: 479  KLPSVHLGVEETGTVNYEIANLIWWRKTFGNVVLIMYCNGPVERTALEWRLLYGRIFRSV 538

Query: 1850 IILSEQSNSELAVERGQLEQAYKYLPKIFD 1939
            +ILSE+ + +L VE G L+ AY+YLPKIFD
Sbjct: 539  VILSEKKDVDLVVEEGHLDYAYRYLPKIFD 568


>ref|XP_003519071.1| PREDICTED: uncharacterized protein LOC100786801 [Glycine max]
          Length = 759

 Score =  912 bits (2356), Expect = 0.0
 Identities = 429/570 (75%), Positives = 504/570 (88%)
 Frame = +2

Query: 230  MFVQDRFSPKPQIRPLPQLHPDRLHPSTKSLDFSSWLSENFYKIIAISLLIVSVAGIFFL 409
            M VQ+R  PK  + P P      L  STKSLDFS+W+S+N  +I+A+ LL+ +VA +FFL
Sbjct: 1    MMVQERSLPK-SVNPKPHTRTAAL-ASTKSLDFSAWVSDNLVRIVAVLLLVATVAALFFL 58

Query: 410  KNVGSSGALMCLQTRAIELERIAFPKVEWNLIKPIVDKTSPYASFQSKRWIVVSVSNYPS 589
            +NVG + AL+C + +A ELERIA+P+V+W+ I PI DKTS ++SF+S++WIVVSVS YPS
Sbjct: 59   RNVGDTAALLCFENQARELERIAYPRVDWSAIAPIADKTSKFSSFRSEKWIVVSVSGYPS 118

Query: 590  NSLRKLVKIKGWQVLAIGNSKTPSDWNLKGAIFLSLDQQASLNFRVVDHLPYDSYVRKSV 769
             +LR+LVK+KGWQV+A+G S TPSDW LKGAIFLSL++Q +L FRVVD+LPYDS+VRKSV
Sbjct: 119  EALRRLVKMKGWQVVAVGGSNTPSDWTLKGAIFLSLEEQVNLGFRVVDYLPYDSFVRKSV 178

Query: 770  GYLFAIQHGAKKIFDADDRGEVIDGDLGKHFDLELIGEKARRQPIMQYSHENPNKTVVNP 949
            GYLFAIQHGAKKIFDADDRGEVID DLGKHFD+EL+GE AR++ ++QYSH+NPN+TVVNP
Sbjct: 179  GYLFAIQHGAKKIFDADDRGEVIDDDLGKHFDVELVGEGARQEVLLQYSHDNPNRTVVNP 238

Query: 950  YIHFGQRSVWPRGLPLENVGEVGHEEFYTELYGGKQLIQQGISNGLPDVDSVFYFTRKSS 1129
            Y+HFGQRSVWPRGLPLE VGE+GHEEFYT+++GG Q IQQGISNGLPDVDSVFYFTRKS 
Sbjct: 239  YVHFGQRSVWPRGLPLEKVGEIGHEEFYTQVFGGMQFIQQGISNGLPDVDSVFYFTRKSV 298

Query: 1130 LEMFDIQFDEHAPKVALPQGMMVPMNSFNTLFHASAFWALMLPVSVSTMASDVLRGYWGQ 1309
            LE FDI+FDEHAPKVALPQGMMVP+NSFNT++H+SAFWALMLPVSVSTMASDVLRGYWGQ
Sbjct: 299  LETFDIRFDEHAPKVALPQGMMVPVNSFNTMYHSSAFWALMLPVSVSTMASDVLRGYWGQ 358

Query: 1310 RLLWEIGGHVVVYPPTVHRFDSIQSYPFSEEKDLHVNVGRLIKFLVQWRSGKHRLFEKIM 1489
            RLLWE+GG+VVVYPPTVHR+D I++YPFSEEKDLHVNVGRLI +L+ WRS KHRLFEKI+
Sbjct: 359  RLLWEVGGYVVVYPPTVHRYDRIEAYPFSEEKDLHVNVGRLINYLISWRSDKHRLFEKIL 418

Query: 1490 QLSYAMAEEGFWTELDVKFTADWLQDLLAVGYQQPRLMTLELGRPRATIGHGDRKEFVPQ 1669
             LS+AMAEEGFWTE DVK TA WLQDLLAVGYQQPRLM+LELGRPRA IGHGD+KEFVPQ
Sbjct: 419  DLSFAMAEEGFWTEKDVKLTAAWLQDLLAVGYQQPRLMSLELGRPRANIGHGDQKEFVPQ 478

Query: 1670 KLPSVHLGVKEVGTVNYEIGNLIQWRKNFGNVVLILFCTSPVERTALEWRLLYGRIFKTV 1849
            KLPSVHLGV+E GTVNYEI NLI+WRK FGNVVLI+ C  PVERTALEWRLLYGRIF++V
Sbjct: 479  KLPSVHLGVEETGTVNYEISNLIRWRKTFGNVVLIMHCNGPVERTALEWRLLYGRIFRSV 538

Query: 1850 IILSEQSNSELAVERGQLEQAYKYLPKIFD 1939
            +ILSE+ + +L V  G L+ AY+YLPKIFD
Sbjct: 539  VILSEKKDVDLVVGEGHLDYAYRYLPKIFD 568