BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Coptis25_contig00002662
         (2757 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002283993.1| PREDICTED: zinc-metallopeptidase, peroxisoma...  1243   0.0  
ref|XP_002308028.1| predicted protein [Populus trichocarpa] gi|2...  1188   0.0  
ref|XP_002532073.1| Insulin-degrading enzyme, putative [Ricinus ...  1181   0.0  
ref|XP_002283970.1| PREDICTED: zinc-metallopeptidase, peroxisoma...  1174   0.0  
ref|NP_001233926.1| insulin degrading enzyme [Solanum lycopersic...  1172   0.0  

>ref|XP_002283993.1| PREDICTED: zinc-metallopeptidase, peroxisomal [Vitis vinifera]
            gi|297739661|emb|CBI29843.3| unnamed protein product
            [Vitis vinifera]
          Length = 965

 Score = 1243 bits (3215), Expect = 0.0
 Identities = 596/798 (74%), Positives = 688/798 (86%), Gaps = 2/798 (0%)
 Frame = +1

Query: 1    PYHKFSTGNWDTLEVRPKEKGIDTRDRLIKFYEENYSANLMHLVVYGKESLNEMQSLVGC 180
            PYHKFSTGNWDTLEV+PKEKG+DTR  LIKFYEE+YSANLMHLVVY KESL+++QSLV  
Sbjct: 168  PYHKFSTGNWDTLEVKPKEKGLDTRHELIKFYEEHYSANLMHLVVYTKESLDKIQSLVEH 227

Query: 181  KFQDISNADRNCFHCPGQPCMPEHLQIIVKAVPVKQGHKLRVIWPITPSIRHYKESPCRY 360
            KFQ+I N DR+ F  PGQPC  EHLQI+VK VP+KQGHKLRVIWPITPSI +YKE PCRY
Sbjct: 228  KFQEIQNKDRSNFQIPGQPCTSEHLQILVKTVPIKQGHKLRVIWPITPSIHNYKEGPCRY 287

Query: 361  LGHLIGHEGEGSLFYVLKKLGWATSLSAGEGDWTYEFSFFKVSIDLTDAGHDHMEDIVGL 540
            LGHLIGHEGEGSLFY+LK LGWATSLSAGEGDWT EFSFFKV IDLT+AGH+HM+DIVGL
Sbjct: 288  LGHLIGHEGEGSLFYILKTLGWATSLSAGEGDWTCEFSFFKVVIDLTEAGHEHMQDIVGL 347

Query: 541  LFKYVLLLQQSGVKEWIFDELSAICETVFHYQDKVRPIDYVVNVASNMQIYPPEDWLVAS 720
            LFKY+ LLQQ+GV +WIFDELSAICETVFHYQDK+ PIDYVVNV+SNM++YPP+DWLV S
Sbjct: 348  LFKYISLLQQTGVCKWIFDELSAICETVFHYQDKIPPIDYVVNVSSNMELYPPKDWLVGS 407

Query: 721  SLPSKFSPETVQMILDELSPSNVRIFWESQKFEGHTDMVEPWYGTAYTIQKITDSVIQQW 900
            SLPSKFSP+ +Q +LDEL+P+NVRIFWES+ FEGHTDMVEPWYGTAY+I+KIT S+IQQW
Sbjct: 408  SLPSKFSPDVIQKVLDELAPNNVRIFWESKNFEGHTDMVEPWYGTAYSIEKITSSMIQQW 467

Query: 901  IVKAPDELLHLPAPNVFIPTDLSLKDVQDKAKFPVLLRQSSYSRLWYKPDTTFSSPKAYV 1080
            ++ AP+E LHLP+PNVFIPTDLSLKDVQ+KAKFPVLLR+SSYS LWYKPDT FS+PKAYV
Sbjct: 468  MLAAPNEHLHLPSPNVFIPTDLSLKDVQEKAKFPVLLRKSSYSTLWYKPDTMFSTPKAYV 527

Query: 1081 NIDFICPYASHSPEAVVLTEIFVRLLMDYLNEYAYDAQVAGLYYGINQADTGFQVIVLGY 1260
             IDF CP+AS SPEA VLT+IF RLLMDYLNEYAY AQVAGLYYGIN  D+GFQV V GY
Sbjct: 528  KIDFNCPFASSSPEADVLTDIFTRLLMDYLNEYAYYAQVAGLYYGINHTDSGFQVAVTGY 587

Query: 1261 NHKLRILVDTVVDQIADFKVKADRFYVIKETVKKEYHNLKFQQPYQQAMYYCSLILEDQS 1440
            NHKLRIL++TVV++IA+FKVK DRF VIKE V KEY N KFQQPYQQAMYYCSLIL+D +
Sbjct: 588  NHKLRILLETVVEKIANFKVKPDRFLVIKEMVTKEYQNFKFQQPYQQAMYYCSLILQDNT 647

Query: 1441 WPWTEQLEVLPHVEADDXXXXXXXXXXXXXXXXYVAGNMEPKEAEAMLCHIEDTFFKGPK 1620
            WPW + LEV+PH+EADD                Y+AGN+EPKEAE+M+ HIED F+ GP 
Sbjct: 648  WPWMDGLEVIPHLEADDLAKFVPMLLSRAFLDCYIAGNIEPKEAESMIHHIEDIFYSGPH 707

Query: 1621 PISRVLLPSEHLTNRIVKLEKGICNFYQCQVLNKDEENSALVHYVQVHRDDFMLNVKLQL 1800
            PIS+ L PS++LTNR++KL++G+  FY  + LN  +ENSALVHY+QVHRDDF+ NVKLQL
Sbjct: 708  PISQPLFPSQYLTNRVIKLDRGMSYFYPAEGLNPSDENSALVHYIQVHRDDFLPNVKLQL 767

Query: 1801 FALIAKQPAFHQLRSVEQLGYITVLMQRYNSGIRGLQFIVQSTVKDPGHINMRVEAFLKD 1980
            FALIAKQ AFHQLRSVEQLGYITVLMQR +SGIRG+QFI+QSTVK PGHI+ RV  FLK 
Sbjct: 768  FALIAKQRAFHQLRSVEQLGYITVLMQRNDSGIRGVQFIIQSTVKGPGHIDSRVVEFLKM 827

Query: 1981 FETKLYELSDNEFRSNVNALIDMKLEKPKNLREESSFYWREIADGTLKFDRKDAEVAALK 2160
            FE+KLY +S++EF+SNVNALIDMKLEK KNLREES FYWREI DGTLKFDR++AEVAALK
Sbjct: 828  FESKLYAMSEDEFKSNVNALIDMKLEKHKNLREESGFYWREIYDGTLKFDRREAEVAALK 887

Query: 2161 CLTKEDLISFFEEHVKVDTPHRKTLAIQVYGSLHSSEYKAAKSET--PLSVQINDIFSFR 2334
             LT+++LI FF EH+KV  P +KTL+++VYG LH+SEY   K E   P  V+I+DIF FR
Sbjct: 888  KLTQKELIDFFNEHIKVGAPQKKTLSVRVYGGLHTSEYADEKKEANQPKQVKIDDIFKFR 947

Query: 2335 RSQSLYGSFKGGLGHTKL 2388
            +SQ LYGSFKGGLG  KL
Sbjct: 948  KSQPLYGSFKGGLGQVKL 965


>ref|XP_002308028.1| predicted protein [Populus trichocarpa] gi|222854004|gb|EEE91551.1|
            predicted protein [Populus trichocarpa]
          Length = 949

 Score = 1188 bits (3074), Expect = 0.0
 Identities = 571/798 (71%), Positives = 672/798 (84%), Gaps = 2/798 (0%)
 Frame = +1

Query: 1    PYHKFSTGNWDTLEVRPKEKGIDTRDRLIKFYEENYSANLMHLVVYGKESLNEMQSLVGC 180
            PYHKFSTGNWDTLEV+PKEKG+DTR  LIK YEENYSANLM+LV+Y KESL+++QSLV  
Sbjct: 152  PYHKFSTGNWDTLEVQPKEKGLDTRLELIKLYEENYSANLMNLVIYAKESLDKIQSLVEE 211

Query: 181  KFQDISNADRNCFHCPGQPCMPEHLQIIVKAVPVKQGHKLRVIWPITPSIRHYKESPCRY 360
            KFQ+I N DR+CF  PGQPC  EHLQI+V+ VP+KQGHKLR++WPITP I HYKE PCRY
Sbjct: 212  KFQEIRNNDRSCFSFPGQPCSSEHLQILVRTVPIKQGHKLRIVWPITPGILHYKEGPCRY 271

Query: 361  LGHLIGHEGEGSLFYVLKKLGWATSLSAGEGDWTYEFSFFKVSIDLTDAGHDHMEDIVGL 540
            LGHLIGHEGEGSLFYVLK LGWAT LSAGE D T EF+FF   I+LTDAGH+HM+D+VGL
Sbjct: 272  LGHLIGHEGEGSLFYVLKTLGWATDLSAGEVDGTTEFAFFTAVINLTDAGHEHMQDVVGL 331

Query: 541  LFKYVLLLQQSGVKEWIFDELSAICETVFHYQDKVRPIDYVVNVASNMQIYPPEDWLVAS 720
            LFKY+ LLQQSGV +WIFDEL+AICET FHYQDK  PI YVV +ASNMQ+YP +DWLV S
Sbjct: 332  LFKYIHLLQQSGVCKWIFDELAAICETSFHYQDKTPPISYVVRIASNMQLYPQKDWLVGS 391

Query: 721  SLPSKFSPETVQMILDELSPSNVRIFWESQKFEGHTDMVEPWYGTAYTIQKITDSVIQQW 900
            SLPS FSP  +Q +L++LSP NVRIFWES+KFEG T M EPWY TAY+++KIT S+IQ+W
Sbjct: 392  SLPSNFSPSIIQTVLNQLSPDNVRIFWESKKFEGQTAMTEPWYKTAYSVEKITGSMIQEW 451

Query: 901  IVKAPDELLHLPAPNVFIPTDLSLKDVQDKAKFPVLLRQSSYSRLWYKPDTTFSSPKAYV 1080
            ++ AP+E LHLPAPNVFIPTDLSLKD Q+K KFPVLLR+SS S LWYKPDT FS+PKAYV
Sbjct: 452  MLFAPNEDLHLPAPNVFIPTDLSLKDAQEKVKFPVLLRKSSSSSLWYKPDTMFSTPKAYV 511

Query: 1081 NIDFICPYASHSPEAVVLTEIFVRLLMDYLNEYAYDAQVAGLYYGINQADTGFQVIVLGY 1260
             IDF CP+AS SPE  VLT+IF RLLMD LN+YAY AQVAGLYYGI+  D+GFQV V+GY
Sbjct: 512  KIDFNCPFASSSPETEVLTDIFARLLMDDLNDYAYYAQVAGLYYGISNTDSGFQVTVVGY 571

Query: 1261 NHKLRILVDTVVDQIADFKVKADRFYVIKETVKKEYHNLKFQQPYQQAMYYCSLILEDQS 1440
            NHKLRIL++TV+++I++FKVK DRF VIKE V KEY NLKFQQPYQQAMYYCSL+L+DQ+
Sbjct: 572  NHKLRILLETVIEKISNFKVKPDRFSVIKEMVTKEYGNLKFQQPYQQAMYYCSLLLQDQT 631

Query: 1441 WPWTEQLEVLPHVEADDXXXXXXXXXXXXXXXXYVAGNMEPKEAEAMLCHIEDTFFKGPK 1620
            WPW EQLE+LPH++A+D                Y+AGN+E  EAE+M+ HIED F +GP 
Sbjct: 632  WPWMEQLEILPHLQAEDLAKFIPLMLSRAFLECYIAGNIERSEAESMILHIEDVFNEGPD 691

Query: 1621 PISRVLLPSEHLTNRIVKLEKGICNFYQCQVLNKDEENSALVHYVQVHRDDFMLNVKLQL 1800
            PI + L PS+HLT+R++KLE+GI   Y  + LN D+ENSALVHY+Q+HRDDF  NVKLQL
Sbjct: 692  PICQPLFPSQHLTSRVIKLERGINYLYPIEGLNPDDENSALVHYIQIHRDDFTWNVKLQL 751

Query: 1801 FALIAKQPAFHQLRSVEQLGYITVLMQRYNSGIRGLQFIVQSTVKDPGHINMRVEAFLKD 1980
             ALIAKQPAFHQLRSVEQLGYITVLMQR +SGIRGLQFI+QSTVK PG I++RVEAFLK 
Sbjct: 752  LALIAKQPAFHQLRSVEQLGYITVLMQRNDSGIRGLQFIIQSTVKGPGQIDLRVEAFLKM 811

Query: 1981 FETKLYELSDNEFRSNVNALIDMKLEKPKNLREESSFYWREIADGTLKFDRKDAEVAALK 2160
            FETKLY ++++EF+SNVNALIDMKLEK KNLREES+F+WREI+DGTLKFDR++ EVAALK
Sbjct: 812  FETKLYGMTNDEFKSNVNALIDMKLEKHKNLREESAFFWREISDGTLKFDRRECEVAALK 871

Query: 2161 CLTKEDLISFFEEHVKVDTPHRKTLAIQVYGSLHSSEYKAAKSE--TPLSVQINDIFSFR 2334
             LT++DLI FF+EHVKV  P ++TL+++VYG LHS EY + KS+   P +VQI DIFSFR
Sbjct: 872  QLTQQDLIDFFDEHVKVGAPRKRTLSVRVYGKLHSCEYPSDKSQQLPPNAVQIEDIFSFR 931

Query: 2335 RSQSLYGSFKGGLGHTKL 2388
            RSQ LYGSFKGG GH KL
Sbjct: 932  RSQPLYGSFKGGFGHMKL 949


>ref|XP_002532073.1| Insulin-degrading enzyme, putative [Ricinus communis]
            gi|223528255|gb|EEF30307.1| Insulin-degrading enzyme,
            putative [Ricinus communis]
          Length = 967

 Score = 1181 bits (3054), Expect = 0.0
 Identities = 561/798 (70%), Positives = 670/798 (83%), Gaps = 2/798 (0%)
 Frame = +1

Query: 1    PYHKFSTGNWDTLEVRPKEKGIDTRDRLIKFYEENYSANLMHLVVYGKESLNEMQSLVGC 180
            PYHKF TGNWDTLEVRPK KG+DTR+ LIKFYEENYSAN MHLV+Y KESL+++Q L+  
Sbjct: 170  PYHKFGTGNWDTLEVRPKAKGLDTRNELIKFYEENYSANRMHLVIYAKESLDKLQILIED 229

Query: 181  KFQDISNADRNCFHCPGQPCMPEHLQIIVKAVPVKQGHKLRVIWPITPSIRHYKESPCRY 360
            KFQ I N DR+C   PGQPC  EHLQI+VKAVP+KQGH+L++IWPITP I HYKE PCRY
Sbjct: 230  KFQHIRNKDRSCLSFPGQPCSSEHLQILVKAVPIKQGHRLKIIWPITPEILHYKEGPCRY 289

Query: 361  LGHLIGHEGEGSLFYVLKKLGWATSLSAGEGDWTYEFSFFKVSIDLTDAGHDHMEDIVGL 540
            LGHLIGHEGEGSLFYVLK LGWATSLSAGEGDWT EFSFFKV IDLTDAGH+HM+DI+GL
Sbjct: 290  LGHLIGHEGEGSLFYVLKTLGWATSLSAGEGDWTMEFSFFKVGIDLTDAGHEHMQDIIGL 349

Query: 541  LFKYVLLLQQSGVKEWIFDELSAICETVFHYQDKVRPIDYVVNVASNMQIYPPEDWLVAS 720
            LFKY+ LLQQSGV EWIF+EL+A+CET FHYQDK+ PIDYVV +A NM IYPP+DWLV S
Sbjct: 350  LFKYIHLLQQSGVSEWIFNELAAVCETSFHYQDKIPPIDYVVTIACNMNIYPPKDWLVGS 409

Query: 721  SLPSKFSPETVQMILDELSPSNVRIFWESQKFEGHTDMVEPWYGTAYTIQKITDSVIQQW 900
            SLPS FSP+ +QM+L +LSP++VRIFWES+ FEG T+ VEPWYGTAY+++KI   VIQ+W
Sbjct: 410  SLPSNFSPDIIQMVLHQLSPNSVRIFWESKNFEGQTEKVEPWYGTAYSVEKIDSLVIQEW 469

Query: 901  IVKAPDELLHLPAPNVFIPTDLSLKDVQDKAKFPVLLRQSSYSRLWYKPDTTFSSPKAYV 1080
            ++ APDE LHLPAPNVFIPTDLSLK  Q+K   PVLLR+SSYS LWYKPDT F++PKAYV
Sbjct: 470  MLSAPDENLHLPAPNVFIPTDLSLKSAQEKVILPVLLRKSSYSSLWYKPDTMFNTPKAYV 529

Query: 1081 NIDFICPYASHSPEAVVLTEIFVRLLMDYLNEYAYDAQVAGLYYGINQADTGFQVIVLGY 1260
             IDF CP+A  SPEA VLT+IF RLLMDYLNEYAY AQVAGLYYGI + D+GFQV ++GY
Sbjct: 530  KIDFSCPHAGSSPEADVLTDIFARLLMDYLNEYAYYAQVAGLYYGITKTDSGFQVTLVGY 589

Query: 1261 NHKLRILVDTVVDQIADFKVKADRFYVIKETVKKEYHNLKFQQPYQQAMYYCSLILEDQS 1440
            NHKL+IL++TV+++IA FKV  DRF VIKE V K+Y N KFQQPYQQA+YY SLIL++Q+
Sbjct: 590  NHKLKILLETVIEKIAKFKVNPDRFSVIKEMVIKKYKNFKFQQPYQQAIYYSSLILQNQA 649

Query: 1441 WPWTEQLEVLPHVEADDXXXXXXXXXXXXXXXXYVAGNMEPKEAEAMLCHIEDTFFKGPK 1620
            WPW E+LEVLPH+ A+D                Y+AGN+E  EAE+++ HIE+ FFKG  
Sbjct: 650  WPWMEELEVLPHLVAEDLAKFVPIMLSRSFLECYIAGNIESIEAESIIEHIENVFFKGQN 709

Query: 1621 PISRVLLPSEHLTNRIVKLEKGICNFYQCQVLNKDEENSALVHYVQVHRDDFMLNVKLQL 1800
            PI + L PS+HLTNR++KL +G   FY  + LN  +ENSALVHY+QVH+DDF+LNVKLQL
Sbjct: 710  PICQPLFPSQHLTNRVMKLGRGKSYFYAIEGLNPSDENSALVHYIQVHQDDFLLNVKLQL 769

Query: 1801 FALIAKQPAFHQLRSVEQLGYITVLMQRYNSGIRGLQFIVQSTVKDPGHINMRVEAFLKD 1980
            FALIAKQPAFHQLRSVEQLGYITVLM R +SGIRG+ FI+QSTVK P HI++RVEAFLK 
Sbjct: 770  FALIAKQPAFHQLRSVEQLGYITVLMPRNDSGIRGVHFIIQSTVKGPVHIDLRVEAFLKS 829

Query: 1981 FETKLYELSDNEFRSNVNALIDMKLEKPKNLREESSFYWREIADGTLKFDRKDAEVAALK 2160
            FETKLYE++++EF++NVN+LIDMKLEK KNL EES FYWREIADGTLKFDR+D+EVAAL+
Sbjct: 830  FETKLYEMTNDEFKNNVNSLIDMKLEKHKNLGEESGFYWREIADGTLKFDRRDSEVAALR 889

Query: 2161 CLTKEDLISFFEEHVKVDTPHRKTLAIQVYGSLHSSEYKAAKSET--PLSVQINDIFSFR 2334
             LT+++ + FF E++KV  P R+TL+I+VYG+ HS+EY + KSE+  P S+QI+DIFSFR
Sbjct: 890  QLTQQEFVDFFNENIKVGAPGRRTLSIRVYGASHSAEYTSDKSESLLPNSIQIDDIFSFR 949

Query: 2335 RSQSLYGSFKGGLGHTKL 2388
            R+QSLYGS +GG GH KL
Sbjct: 950  RTQSLYGSCRGGFGHMKL 967


>ref|XP_002283970.1| PREDICTED: zinc-metallopeptidase, peroxisomal [Vitis vinifera]
            gi|297739662|emb|CBI29844.3| unnamed protein product
            [Vitis vinifera]
          Length = 965

 Score = 1174 bits (3038), Expect = 0.0
 Identities = 568/798 (71%), Positives = 669/798 (83%), Gaps = 2/798 (0%)
 Frame = +1

Query: 1    PYHKFSTGNWDTLEVRPKEKGIDTRDRLIKFYEENYSANLMHLVVYGKESLNEMQSLVGC 180
            PYHKFSTGN DTLEV+PKEKG+DTR  LIKFYEE+YSANLMHLVVY KESL+++QSLV  
Sbjct: 168  PYHKFSTGNRDTLEVKPKEKGLDTRHELIKFYEEHYSANLMHLVVYTKESLDKIQSLVEH 227

Query: 181  KFQDISNADRNCFHCPGQPCMPEHLQIIVKAVPVKQGHKLRVIWPITPSIRHYKESPCRY 360
            KFQ+I N DR  FH  GQPC  EHLQI+VK VP+KQGHKL V+WPITPSI +YKE PCRY
Sbjct: 228  KFQEIQNKDRINFHICGQPCTSEHLQILVKTVPIKQGHKLIVVWPITPSIHNYKEGPCRY 287

Query: 361  LGHLIGHEGEGSLFYVLKKLGWATSLSAGEGDWTYEFSFFKVSIDLTDAGHDHMEDIVGL 540
            LGHLIGHEG+GSLFY+LK LGWATSLSA E DWT EFSFF+V IDLTDAGH+HM+DIVGL
Sbjct: 288  LGHLIGHEGKGSLFYILKTLGWATSLSAWEEDWTCEFSFFEVVIDLTDAGHEHMQDIVGL 347

Query: 541  LFKYVLLLQQSGVKEWIFDELSAICETVFHYQDKVRPIDYVVNVASNMQIYPPEDWLVAS 720
            LFKY+ LLQQ+GV +WIFDELSAICET+FHYQDK+  IDYVVNV+SNM++YPP+DWLV S
Sbjct: 348  LFKYISLLQQTGVCKWIFDELSAICETMFHYQDKIPSIDYVVNVSSNMELYPPKDWLVGS 407

Query: 721  SLPSKFSPETVQMILDELSPSNVRIFWESQKFEGHTDMVEPWYGTAYTIQKITDSVIQQW 900
            SLPSKFSP+ +Q +LDEL+P+NVRIFWES+ FEGHTDMVEPWYGTA++I+KIT S+IQQW
Sbjct: 408  SLPSKFSPDVIQKVLDELAPNNVRIFWESKNFEGHTDMVEPWYGTAFSIEKITVSMIQQW 467

Query: 901  IVKAPDELLHLPAPNVFIPTDLSLKDVQDKAKFPVLLRQSSYSRLWYKPDTTFSSPKAYV 1080
            ++ AP E LHLP PN FIPTDLSLK+VQ+KAKFPVLLR+SSYS LWYKPDT FS+PKAYV
Sbjct: 468  MLAAPTEHLHLPDPNDFIPTDLSLKNVQEKAKFPVLLRKSSYSTLWYKPDTMFSTPKAYV 527

Query: 1081 NIDFICPYASHSPEAVVLTEIFVRLLMDYLNEYAYDAQVAGLYYGINQADTGFQVIVLGY 1260
             IDF CP+AS SPEA VLT+IF RLLMDYLNE AY A+VAGLYY ++  D+GFQV + GY
Sbjct: 528  KIDFNCPFASSSPEADVLTDIFTRLLMDYLNEDAYYAEVAGLYYCLSNTDSGFQVAMAGY 587

Query: 1261 NHKLRILVDTVVDQIADFKVKADRFYVIKETVKKEYHNLKFQQPYQQAMYYCSLILEDQS 1440
            NHKLRIL++TVV +IA+FKVK DRF VIKE V K Y N+KFQQPYQQAM Y SLIL D +
Sbjct: 588  NHKLRILLETVVKKIANFKVKPDRFLVIKELVTKGYQNVKFQQPYQQAMCYRSLILHDNT 647

Query: 1441 WPWTEQLEVLPHVEADDXXXXXXXXXXXXXXXXYVAGNMEPKEAEAMLCHIEDTFFKGPK 1620
            WPW + LEV+PH+EADD                Y+AGN+EPKEAEAM+ HIED F+ GP+
Sbjct: 648  WPWMDGLEVIPHLEADDLAKFVPMLLSRAFLECYIAGNIEPKEAEAMIHHIEDIFYSGPR 707

Query: 1621 PISRVLLPSEHLTNRIVKLEKGICNFYQCQVLNKDEENSALVHYVQVHRDDFMLNVKLQL 1800
            PI + L PS++LTNR++KL++G+  FY  + LN  +ENSALVHY+QVHRDDF+ NVKLQL
Sbjct: 708  PICQPLFPSQYLTNRVIKLDRGMSYFYPAEGLNPSDENSALVHYIQVHRDDFLPNVKLQL 767

Query: 1801 FALIAKQPAFHQLRSVEQLGYITVLMQRYNSGIRGLQFIVQSTVKDPGHINMRVEAFLKD 1980
            FALIAKQ AFHQLRSVEQLGYIT LM R +SGI G+QF++QSTVK PGHI+ R+E FLK 
Sbjct: 768  FALIAKQQAFHQLRSVEQLGYITELMLRNDSGIHGVQFMIQSTVKGPGHIDSRIEEFLKM 827

Query: 1981 FETKLYELSDNEFRSNVNALIDMKLEKPKNLREESSFYWREIADGTLKFDRKDAEVAALK 2160
            FE KLY +S++EF+SNVN L+DMKLEK KNL EES FYW+EI DGTLKFDR +AEVAALK
Sbjct: 828  FEFKLYAMSEDEFKSNVNTLVDMKLEKYKNLWEESGFYWQEIYDGTLKFDRTEAEVAALK 887

Query: 2161 CLTKEDLISFFEEHVKVDTPHRKTLAIQVYGSLHSSEYKAAKSET--PLSVQINDIFSFR 2334
             LT+++LI FF EH+KV  P +KTL+++VYG LH+SEY   + E   P+ V+I+DIF FR
Sbjct: 888  KLTQKELIDFFNEHIKVGAPQKKTLSVRVYGCLHTSEYAEEQKEANQPIQVKIDDIFKFR 947

Query: 2335 RSQSLYGSFKGGLGHTKL 2388
            +SQ LYGSFKGGLGH KL
Sbjct: 948  KSQPLYGSFKGGLGHVKL 965


>ref|NP_001233926.1| insulin degrading enzyme [Solanum lycopersicum]
            gi|15485612|emb|CAC67408.1| insulin degrading enzyme
            [Solanum lycopersicum]
          Length = 971

 Score = 1172 bits (3031), Expect = 0.0
 Identities = 557/798 (69%), Positives = 660/798 (82%), Gaps = 2/798 (0%)
 Frame = +1

Query: 1    PYHKFSTGNWDTLEVRPKEKGIDTRDRLIKFYEENYSANLMHLVVYGKESLNEMQSLVGC 180
            PYHKFSTG+WDTLEVRPKE+GIDTR  L+KFY ENYSANLMHLVVY K+SL++++ LV  
Sbjct: 174  PYHKFSTGSWDTLEVRPKERGIDTRQELLKFYSENYSANLMHLVVYSKDSLDKVEQLVRG 233

Query: 181  KFQDISNADRNCFHCPGQPCMPEHLQIIVKAVPVKQGHKLRVIWPITPSIRHYKESPCRY 360
            KFQDI N DRN  H  GQPC+ EHLQI+V+AVP+KQGHKL++IWPITP I HYKE PCRY
Sbjct: 234  KFQDIRNIDRNQIHFTGQPCIMEHLQILVRAVPIKQGHKLKIIWPITPGIHHYKEGPCRY 293

Query: 361  LGHLIGHEGEGSLFYVLKKLGWATSLSAGEGDWTYEFSFFKVSIDLTDAGHDHMEDIVGL 540
            LGHLIGHEGEGSLFYVLKKLGWATSLSAGE DWT EFSFFKV+IDLTDAG DH EDI+GL
Sbjct: 294  LGHLIGHEGEGSLFYVLKKLGWATSLSAGESDWTNEFSFFKVAIDLTDAGQDHFEDIMGL 353

Query: 541  LFKYVLLLQQSGVKEWIFDELSAICETVFHYQDKVRPIDYVVNVASNMQIYPPEDWLVAS 720
            LFKY+ LLQQ+G  +WIF+ELSAICET FHYQDK+RP DYVVNVA NMQ YPPEDWLVAS
Sbjct: 354  LFKYIHLLQQAGASKWIFEELSAICETAFHYQDKIRPSDYVVNVAMNMQHYPPEDWLVAS 413

Query: 721  SLPSKFSPETVQMILDELSPSNVRIFWESQKFEGHTDMVEPWYGTAYTIQKITDSVIQQW 900
            SLPSKF+P  +Q  L+EL+P NVRIFWES KFEG+T M EPWYGTAY+I+K+    I+QW
Sbjct: 414  SLPSKFNPSIIQSFLNELNPDNVRIFWESTKFEGNTSMTEPWYGTAYSIEKVGGDSIKQW 473

Query: 901  IVKAPDELLHLPAPNVFIPTDLSLKDVQDKAKFPVLLRQSSYSRLWYKPDTTFSSPKAYV 1080
            +  AP E LHLPAPNVFIPTDLSLK V +K K P+LLR+S YSRLWYKPDT FSSPKAYV
Sbjct: 474  MEHAPSEELHLPAPNVFIPTDLSLKPVFEKTKVPILLRKSPYSRLWYKPDTAFSSPKAYV 533

Query: 1081 NIDFICPYASHSPEAVVLTEIFVRLLMDYLNEYAYDAQVAGLYYGINQADTGFQVIVLGY 1260
             IDF CPY  HSPEA VLTEIF RLLMDYLNEYAY+AQVAGLYY I++ ++GFQ+ + GY
Sbjct: 534  MIDFSCPYCGHSPEAEVLTEIFTRLLMDYLNEYAYNAQVAGLYYDISKTNSGFQLTLFGY 593

Query: 1261 NHKLRILVDTVVDQIADFKVKADRFYVIKETVKKEYHNLKFQQPYQQAMYYCSLILEDQS 1440
            N KLR+L++ V++++A F+VK DRF V+KE V K+Y N KFQQPYQQ MYYCSL+L+D  
Sbjct: 594  NDKLRVLLEAVIEKVAKFEVKPDRFSVVKELVTKQYQNFKFQQPYQQVMYYCSLLLKDNI 653

Query: 1441 WPWTEQLEVLPHVEADDXXXXXXXXXXXXXXXXYVAGNMEPKEAEAMLCHIEDTFFKGPK 1620
            WPW E+L+VLPH++ DD                YVAGN+E  EAE+M+  IED FFKGP+
Sbjct: 654  WPWNEELDVLPHLKVDDLVKFYPLLMARSFMECYVAGNVEQAEAESMIQLIEDVFFKGPQ 713

Query: 1621 PISRVLLPSEHLTNRIVKLEKGICNFYQCQVLNKDEENSALVHYVQVHRDDFMLNVKLQL 1800
             IS+ L  S+HLTNR+V LE+G+   Y  + LN  +ENSALVHY+QVH+DDFMLNVKLQL
Sbjct: 714  SISKPLFASQHLTNRVVNLERGVNYVYAAEGLNPSDENSALVHYIQVHQDDFMLNVKLQL 773

Query: 1801 FALIAKQPAFHQLRSVEQLGYITVLMQRYNSGIRGLQFIVQSTVKDPGHINMRVEAFLKD 1980
            FALIAKQPAFHQLRSVEQLGYITVLMQR +SG+ G+QFIVQST KDP +I+ RVE F+K 
Sbjct: 774  FALIAKQPAFHQLRSVEQLGYITVLMQRSDSGVHGVQFIVQSTAKDPKYIDTRVELFMKM 833

Query: 1981 FETKLYELSDNEFRSNVNALIDMKLEKPKNLREESSFYWREIADGTLKFDRKDAEVAALK 2160
            FE+KLYE++ +EF++NVNALIDMKLEK KNLREES FYWREI+DGTLKFDR+D E+ ALK
Sbjct: 834  FESKLYEMTSDEFKNNVNALIDMKLEKHKNLREESRFYWREISDGTLKFDRRDREIVALK 893

Query: 2161 CLTKEDLISFFEEHVKVDTPHRKTLAIQVYGSLHSSEYKAAKSE--TPLSVQINDIFSFR 2334
             LT+++L  FF+E++KV  P +K L+++VYGS HSS+++A K+E   P +VQI +IFSFR
Sbjct: 894  QLTQKELTDFFDEYIKVGVPRKKALSVRVYGSSHSSQFQAHKNEQMEPNAVQIEEIFSFR 953

Query: 2335 RSQSLYGSFKGGLGHTKL 2388
            RS+ LY SFKGG GH +L
Sbjct: 954  RSRPLYSSFKGGFGHVRL 971