BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Coptis25_contig00001608
         (2346 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002510732.1| hmg-CoA reductase, putative [Ricinus communi...   830   0.0  
gb|AAD03789.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase [...   825   0.0  
gb|AAV54051.1| 3-hydroxy-3-methylglutaryl coenzyme A reductase [...   822   0.0  
gb|AEZ55673.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase 4...   820   0.0  
gb|ACD37361.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase [...   817   0.0  

>ref|XP_002510732.1| hmg-CoA reductase, putative [Ricinus communis]
            gi|223551433|gb|EEF52919.1| hmg-CoA reductase, putative
            [Ricinus communis]
          Length = 576

 Score =  830 bits (2145), Expect = 0.0
 Identities = 428/537 (79%), Positives = 466/537 (86%), Gaps = 12/537 (2%)
 Frame = +2

Query: 188  ASDALPLPLYLTNXXXXXXXXSVAYFLLHRWREKIRTSIPLHVLTLSEITAILSLIASFI 367
            ASDALPLPLYLTN        SVAY+LLHRWR+KIR S PLHVLTLSEI AI+SLIASFI
Sbjct: 38   ASDALPLPLYLTNAIFFTLFFSVAYYLLHRWRDKIRNSTPLHVLTLSEIAAIVSLIASFI 97

Query: 368  YLLGFFGIDFVQSLIPLRPIXXXXXXDVD-RFITRLRPSLIPPPP-----------KTFX 511
            YLLGFFGIDFVQS I             D  ++ R    L+  PP            T  
Sbjct: 98   YLLGFFGIDFVQSFITRASHESWDLDGADPDYLIREDHRLVTCPPIPSKLPISESIITRL 157

Query: 512  XXXXXXXXXXSVVSGTTPSYSLESKLGDCKRAASIRREALQRVTGKSLTGLPLDGFDYES 691
                      SVV+GT PSYSLESKLGDCKRAA+IRREALQR+ G+SL GLPL+GFDYES
Sbjct: 158  ASEEDEEIVKSVVNGTIPSYSLESKLGDCKRAATIRREALQRMMGRSLEGLPLEGFDYES 217

Query: 692  ILGQCCEMPVGYVQIPVGIAGPLLLDGTEYSVPMATTEGCLVASTNRGCKAIHVSGGATS 871
            ILGQCCEMPVGYVQIPVGIAGPLLLDG EYSVPMATTEGCLVASTNRGCKAIH+SGGA S
Sbjct: 218  ILGQCCEMPVGYVQIPVGIAGPLLLDGREYSVPMATTEGCLVASTNRGCKAIHLSGGANS 277

Query: 872  VLLRDAMTRAPVVRFGSAKRAADLKFYMEDPDNFDTLSVVFNRSSRFGRFQGIKCAIAGK 1051
            VLL+D MTRAPVVRFGSA RAA+LKF++E+P+NFDTLSVVFNRSSRF + Q I+CAIAGK
Sbjct: 278  VLLKDGMTRAPVVRFGSAARAAELKFFLENPENFDTLSVVFNRSSRFAKLQAIQCAIAGK 337

Query: 1052 NLYLRFSCSTGDAMGMNMVSKGVQNVLDYLQNDFPDMEVVSISGNFCSDKKPAAVNWIEG 1231
            NLY+RFSCSTGDAMGMNMVSKGVQNVLD+LQNDFPDM+V+ ISGNFCSDKKPAAVNWIEG
Sbjct: 338  NLYMRFSCSTGDAMGMNMVSKGVQNVLDFLQNDFPDMDVIGISGNFCSDKKPAAVNWIEG 397

Query: 1232 RGKSVVCEAIIKEDVVKKVLKTTIPALVELNMLKNLTGSAIAGALGGFNAHASNIVSAVF 1411
            RGKSVVCEAIIKE+VVKKVLKT + +LVELN+LKNLTGSA+AGALGGFNAHA+NIVSA+F
Sbjct: 398  RGKSVVCEAIIKEEVVKKVLKTNVASLVELNVLKNLTGSAVAGALGGFNAHAANIVSAIF 457

Query: 1412 IATGQDPAQNIESSHCITMMEAVNDGKDLHVSVTMPSIEVGTVGGGTQLASQSACLNLLG 1591
            IATGQDPAQN+ESSHCITMMEAVNDGKDLHVSVTMPSIEVGTVGGGTQLASQSACLNLLG
Sbjct: 458  IATGQDPAQNVESSHCITMMEAVNDGKDLHVSVTMPSIEVGTVGGGTQLASQSACLNLLG 517

Query: 1592 VKGANQESPGSNSRLLATIVAGAVLAGELSLMSALAAGQLVKSHMKYNRSSKDVTKA 1762
            VKGA++ESPGSNSRLLATIVAG+VLAGELSLMSA+AAGQLVKSHMKYNRSS+DV+KA
Sbjct: 518  VKGASKESPGSNSRLLATIVAGSVLAGELSLMSAIAAGQLVKSHMKYNRSSRDVSKA 574


>gb|AAD03789.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Morus alba]
          Length = 548

 Score =  825 bits (2130), Expect = 0.0
 Identities = 425/539 (78%), Positives = 466/539 (86%), Gaps = 2/539 (0%)
 Frame = +2

Query: 149  QERKVVPAAQQQLASDALPLPLYLTNXXXXXXXXSVAYFLLHRWREKIRTSIPLHVLTLS 328
            Q RK  P+     ASDALPLPLYLTN        SVAY+LLHRWR+KIR S PLHV+T  
Sbjct: 11   QSRK--PSQAPPKASDALPLPLYLTNAVFFTLFFSVAYYLLHRWRDKIRNSTPLHVVTFP 68

Query: 329  EITAILSLIASFIYLLGFFGIDFVQSLIPLRPIXXXXXXDVDRFITRLRPSLIPPPPKTF 508
            EI AI+SLIASFIYLLGFFGIDFVQS I + P       D D  +  +R +   PPP   
Sbjct: 69   EIAAIVSLIASFIYLLGFFGIDFVQSFI-ISPRASDDEEDDDLHVV-VRDNACRPPPLVV 126

Query: 509  XXXXXXXXXXX--SVVSGTTPSYSLESKLGDCKRAASIRREALQRVTGKSLTGLPLDGFD 682
                         SVV GT PSYSLES+LGDCKR A+IRREALQR+TG+S+ GLP++GFD
Sbjct: 127  PTLASEEDEEIIRSVVDGTIPSYSLESRLGDCKRGAAIRREALQRMTGRSIEGLPIEGFD 186

Query: 683  YESILGQCCEMPVGYVQIPVGIAGPLLLDGTEYSVPMATTEGCLVASTNRGCKAIHVSGG 862
            YESILGQCCEMPVGYVQIPVGIAGPLLLD  EYSVPMATTEGCLVASTNRGCKAI++SGG
Sbjct: 187  YESILGQCCEMPVGYVQIPVGIAGPLLLDEFEYSVPMATTEGCLVASTNRGCKAIYMSGG 246

Query: 863  ATSVLLRDAMTRAPVVRFGSAKRAADLKFYMEDPDNFDTLSVVFNRSSRFGRFQGIKCAI 1042
            ATSVLLRD MTRAPVVRF SAKRA++LKF++EDP NFDTL+VVFNRSSRF R QGI+CAI
Sbjct: 247  ATSVLLRDGMTRAPVVRFNSAKRASELKFFVEDPVNFDTLAVVFNRSSRFARLQGIQCAI 306

Query: 1043 AGKNLYLRFSCSTGDAMGMNMVSKGVQNVLDYLQNDFPDMEVVSISGNFCSDKKPAAVNW 1222
            AGKN+Y+RFSCSTGDAMGMNMVSKGVQN LDYLQ+DFPDM+++ ISGNFCSDKKPAAVNW
Sbjct: 307  AGKNVYMRFSCSTGDAMGMNMVSKGVQNALDYLQSDFPDMDIIGISGNFCSDKKPAAVNW 366

Query: 1223 IEGRGKSVVCEAIIKEDVVKKVLKTTIPALVELNMLKNLTGSAIAGALGGFNAHASNIVS 1402
            IEGRGKSVVCEA+IKE+VVKKVLKT + ALVELNMLKNL GSA+AGALGG+NAHASNIVS
Sbjct: 367  IEGRGKSVVCEAVIKEEVVKKVLKTNVDALVELNMLKNLAGSAVAGALGGYNAHASNIVS 426

Query: 1403 AVFIATGQDPAQNIESSHCITMMEAVNDGKDLHVSVTMPSIEVGTVGGGTQLASQSACLN 1582
            AVFIATGQDPAQNIESSHCITMMEAVN+GKDLH+SVTMPSIEVGTVGGGTQLASQSACLN
Sbjct: 427  AVFIATGQDPAQNIESSHCITMMEAVNNGKDLHISVTMPSIEVGTVGGGTQLASQSACLN 486

Query: 1583 LLGVKGANQESPGSNSRLLATIVAGAVLAGELSLMSALAAGQLVKSHMKYNRSSKDVTK 1759
            LLGVKGAN+ES GSN+RLLATIVAG+VLAGELSLMSA+AAGQLVKSHMKYNRSSKDVTK
Sbjct: 487  LLGVKGANKESAGSNARLLATIVAGSVLAGELSLMSAIAAGQLVKSHMKYNRSSKDVTK 545


>gb|AAV54051.1| 3-hydroxy-3-methylglutaryl coenzyme A reductase [Eucommia ulmoides]
          Length = 590

 Score =  822 bits (2122), Expect = 0.0
 Identities = 419/549 (76%), Positives = 465/549 (84%), Gaps = 25/549 (4%)
 Frame = +2

Query: 188  ASDALPLPLYLTNXXXXXXXXSVAYFLLHRWREKIRTSIPLHVLTLSEITAILSLIASFI 367
            ASDALPLPLYLTN        SVAY+LLHRWR+KIR S PLHVLTLSE+ AI+SLIASFI
Sbjct: 41   ASDALPLPLYLTNGIFFTLFFSVAYYLLHRWRDKIRNSTPLHVLTLSELAAIVSLIASFI 100

Query: 368  YLLGFFGIDFVQSLIPLRPIXXXXXXDVDRFITR-------------------------L 472
            YLLGFFGIDFVQS I           D +RFI                           +
Sbjct: 101  YLLGFFGIDFVQSFIARASHDPWDVDDDERFILEEDRRRGPCTAALDCLVGPVAPSISDV 160

Query: 473  RPSLIPPPPKTFXXXXXXXXXXXSVVSGTTPSYSLESKLGDCKRAASIRREALQRVTGKS 652
            R  + PP P              SV+SGT PSYSLESKLGDC RAASIRREA+QR+TGKS
Sbjct: 161  RKLMDPPAP---LPSVEDEQMVKSVISGTVPSYSLESKLGDCYRAASIRREAIQRITGKS 217

Query: 653  LTGLPLDGFDYESILGQCCEMPVGYVQIPVGIAGPLLLDGTEYSVPMATTEGCLVASTNR 832
            L+GLPL+GFDYE+ILGQCCEMP+G++QIPVGIAGPLLL+G EYSVPMATTEGCLVASTNR
Sbjct: 218  LSGLPLEGFDYEAILGQCCEMPIGFLQIPVGIAGPLLLNGCEYSVPMATTEGCLVASTNR 277

Query: 833  GCKAIHVSGGATSVLLRDAMTRAPVVRFGSAKRAADLKFYMEDPDNFDTLSVVFNRSSRF 1012
            GCKAI+ SGGATS+LLRD MTRAPVVRF SAKRA++LKF++EDP NF+TLS+VFN+SSRF
Sbjct: 278  GCKAIYASGGATSILLRDGMTRAPVVRFPSAKRASELKFFLEDPLNFETLSMVFNKSSRF 337

Query: 1013 GRFQGIKCAIAGKNLYLRFSCSTGDAMGMNMVSKGVQNVLDYLQNDFPDMEVVSISGNFC 1192
             R QGI+C+IAGKNLY+RF+CSTGDAMGMNMVSKGVQN+L++LQNDFPDM+V+ ISGNFC
Sbjct: 338  ARLQGIQCSIAGKNLYMRFTCSTGDAMGMNMVSKGVQNILEFLQNDFPDMDVIGISGNFC 397

Query: 1193 SDKKPAAVNWIEGRGKSVVCEAIIKEDVVKKVLKTTIPALVELNMLKNLTGSAIAGALGG 1372
            SDKKPAAVNWIEGRGKSVVCEAII ED+V+KVLKTT+PALVELNMLKNL GSA+AGALGG
Sbjct: 398  SDKKPAAVNWIEGRGKSVVCEAIISEDIVRKVLKTTVPALVELNMLKNLAGSAVAGALGG 457

Query: 1373 FNAHASNIVSAVFIATGQDPAQNIESSHCITMMEAVNDGKDLHVSVTMPSIEVGTVGGGT 1552
            FNAHA+NIVSAVFIATGQDPAQNIESSHCITMMEAVNDGKDLH+SVTMPSIEVGTVGGGT
Sbjct: 458  FNAHAANIVSAVFIATGQDPAQNIESSHCITMMEAVNDGKDLHISVTMPSIEVGTVGGGT 517

Query: 1553 QLASQSACLNLLGVKGANQESPGSNSRLLATIVAGAVLAGELSLMSALAAGQLVKSHMKY 1732
            QLASQSACLNLLGVKGAN+ESPGSNSRLLA IVAG+VLAGELSLMSA+AAGQLV SHMKY
Sbjct: 518  QLASQSACLNLLGVKGANKESPGSNSRLLAAIVAGSVLAGELSLMSAIAAGQLVNSHMKY 577

Query: 1733 NRSSKDVTK 1759
            NRS++D TK
Sbjct: 578  NRSNRDFTK 586


>gb|AEZ55673.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase 4 [Salvia
            miltiorrhiza]
          Length = 550

 Score =  820 bits (2119), Expect = 0.0
 Identities = 417/526 (79%), Positives = 459/526 (87%), Gaps = 2/526 (0%)
 Frame = +2

Query: 188  ASDALPLPLYLTNXXXXXXXXSVAYFLLHRWREKIRTSIPLHVLTLSEITAILSLIASFI 367
            ASDALPLPL+LTN        SVAYFLLHRWREKIR+S+PLHVLTLSE+ A+LSLIASFI
Sbjct: 26   ASDALPLPLFLTNGIFFTLFFSVAYFLLHRWREKIRSSVPLHVLTLSELAAVLSLIASFI 85

Query: 368  YLLGFFGIDFVQSLIPLRPIXXXXXXDVDRFI--TRLRPSLIPPPPKTFXXXXXXXXXXX 541
            YLLGFFGIDFVQS I           D DR I  + +  S+IP P               
Sbjct: 86   YLLGFFGIDFVQSFIS----KSDGEIDEDRAIHCSSIPDSIIPKPENPPNLPEDEEEIIN 141

Query: 542  SVVSGTTPSYSLESKLGDCKRAASIRREALQRVTGKSLTGLPLDGFDYESILGQCCEMPV 721
             VVSG  PSYSLESKLGDC +AA IRREALQR TG+S+ GLPL+GFDYE+ILGQCCEMPV
Sbjct: 142  RVVSGEIPSYSLESKLGDCFKAAKIRREALQRQTGRSVEGLPLEGFDYEAILGQCCEMPV 201

Query: 722  GYVQIPVGIAGPLLLDGTEYSVPMATTEGCLVASTNRGCKAIHVSGGATSVLLRDAMTRA 901
            GYVQIPVGIAGPLLL+G EYSVPMATTEGCLVASTNRGCKAI+ SGGA  VLLRD MTRA
Sbjct: 202  GYVQIPVGIAGPLLLNGREYSVPMATTEGCLVASTNRGCKAIYASGGAVCVLLRDGMTRA 261

Query: 902  PVVRFGSAKRAADLKFYMEDPDNFDTLSVVFNRSSRFGRFQGIKCAIAGKNLYLRFSCST 1081
            PVVRF SAKRA++LKF++EDP NFDTLSVVFN+SSRF R Q IKCAIAGKNLY+RF CST
Sbjct: 262  PVVRFSSAKRASELKFFLEDPLNFDTLSVVFNKSSRFARLQDIKCAIAGKNLYIRFRCST 321

Query: 1082 GDAMGMNMVSKGVQNVLDYLQNDFPDMEVVSISGNFCSDKKPAAVNWIEGRGKSVVCEAI 1261
            GDAMGMNMVSKGVQNVLDYL N+FPDM+V+ ISGNFCSDKKPAAVNWIEGRGKSVVCEA+
Sbjct: 322  GDAMGMNMVSKGVQNVLDYLHNEFPDMDVIGISGNFCSDKKPAAVNWIEGRGKSVVCEAV 381

Query: 1262 IKEDVVKKVLKTTIPALVELNMLKNLTGSAIAGALGGFNAHASNIVSAVFIATGQDPAQN 1441
            ++ DVV K+LKTT+PALVELNMLKNLTGSAIAGALGGFNAHA+NIVSAVF+ATGQDPAQN
Sbjct: 382  LRGDVVAKILKTTVPALVELNMLKNLTGSAIAGALGGFNAHAANIVSAVFLATGQDPAQN 441

Query: 1442 IESSHCITMMEAVNDGKDLHVSVTMPSIEVGTVGGGTQLASQSACLNLLGVKGANQESPG 1621
            +ESSHCITMMEAVNDGKDLH+SVTMPSIEVGTVGGGTQLASQSACLNLLGVKGA++ESPG
Sbjct: 442  VESSHCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQSACLNLLGVKGASKESPG 501

Query: 1622 SNSRLLATIVAGAVLAGELSLMSALAAGQLVKSHMKYNRSSKDVTK 1759
            SNS+LLA +VAG+VLAGELSLMSA+AAGQLVKSHMKYNRSS+D+T+
Sbjct: 502  SNSQLLAAVVAGSVLAGELSLMSAIAAGQLVKSHMKYNRSSRDITR 547


>gb|ACD37361.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Salvia miltiorrhiza]
          Length = 565

 Score =  817 bits (2111), Expect = 0.0
 Identities = 418/534 (78%), Positives = 457/534 (85%), Gaps = 10/534 (1%)
 Frame = +2

Query: 188  ASDALPLPLYLTNXXXXXXXXSVAYFLLHRWREKIRTSIPLHVLTLSEITAILSLIASFI 367
            ASDALPLPLYLTN        SVAYFLLHRWR+KIR S PLH+LTLSE+  IL LIASFI
Sbjct: 33   ASDALPLPLYLTNGIFFTLFFSVAYFLLHRWRDKIRNSTPLHILTLSELAGILCLIASFI 92

Query: 368  YLLGFFGIDFVQSLIPLRPIXXXXXXDVDRFIT----RLRPSLIPPPP------KTFXXX 517
            YLLGFFGIDFVQS I           D  RFI     ++   L PP P            
Sbjct: 93   YLLGFFGIDFVQSFIS----KPESDEDHQRFILHEDRKIHCGLPPPAPVVAKAKAAVELP 148

Query: 518  XXXXXXXXSVVSGTTPSYSLESKLGDCKRAASIRREALQRVTGKSLTGLPLDGFDYESIL 697
                     VVSG  PSYSLES+LGDC RAA IRREA+QR+TG+ + GLPL+GFDY+SIL
Sbjct: 149  QDDEEVVDRVVSGEIPSYSLESRLGDCLRAAKIRREAVQRLTGRGVDGLPLEGFDYDSIL 208

Query: 698  GQCCEMPVGYVQIPVGIAGPLLLDGTEYSVPMATTEGCLVASTNRGCKAIHVSGGATSVL 877
            GQCCEMPVGYVQIPVGIAGPLLL+G EYSVPMATTEGCLVASTNRGCKAI+ SGGAT VL
Sbjct: 209  GQCCEMPVGYVQIPVGIAGPLLLNGCEYSVPMATTEGCLVASTNRGCKAIYASGGATCVL 268

Query: 878  LRDAMTRAPVVRFGSAKRAADLKFYMEDPDNFDTLSVVFNRSSRFGRFQGIKCAIAGKNL 1057
            LRDAMTRAPVVRF SAKRA +LKF++EDP NFDTLSVVFN+SSRF R Q ++CAIAGKNL
Sbjct: 269  LRDAMTRAPVVRFSSAKRATELKFFLEDPLNFDTLSVVFNKSSRFARLQNVQCAIAGKNL 328

Query: 1058 YLRFSCSTGDAMGMNMVSKGVQNVLDYLQNDFPDMEVVSISGNFCSDKKPAAVNWIEGRG 1237
            Y+RFSCSTGDAMGMNMVSKGVQNVLD+LQNDFPDM+V+ ISGN+CSDKKP+AVNWIEGRG
Sbjct: 329  YIRFSCSTGDAMGMNMVSKGVQNVLDFLQNDFPDMDVIGISGNYCSDKKPSAVNWIEGRG 388

Query: 1238 KSVVCEAIIKEDVVKKVLKTTIPALVELNMLKNLTGSAIAGALGGFNAHASNIVSAVFIA 1417
            KSVVCEA+I  DVV KVLKTT+P+LVELNMLKNLTGSAIAGALGGFNAHA+NIVSA+FIA
Sbjct: 389  KSVVCEAVITADVVSKVLKTTVPSLVELNMLKNLTGSAIAGALGGFNAHAANIVSAIFIA 448

Query: 1418 TGQDPAQNIESSHCITMMEAVNDGKDLHVSVTMPSIEVGTVGGGTQLASQSACLNLLGVK 1597
            TGQDPAQNIESSHCITMMEA+NDGKDLH+SVTMPSIEVGTVGGGTQLASQSACLNLLGVK
Sbjct: 449  TGQDPAQNIESSHCITMMEAINDGKDLHISVTMPSIEVGTVGGGTQLASQSACLNLLGVK 508

Query: 1598 GANQESPGSNSRLLATIVAGAVLAGELSLMSALAAGQLVKSHMKYNRSSKDVTK 1759
            GAN+ESPGSN+RLLATIVAGAVLAGELSLMSA++AGQLVKSHMKYNRSS+D+TK
Sbjct: 509  GANKESPGSNARLLATIVAGAVLAGELSLMSAISAGQLVKSHMKYNRSSRDITK 562