BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Coptis24_contig00003710
         (2149 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

emb|CBI29877.3| unnamed protein product [Vitis vinifera]             1025   0.0  
ref|XP_002277596.1| PREDICTED: uncharacterized protein LOC100267...  1025   0.0  
emb|CAN80640.1| hypothetical protein VITISV_016911 [Vitis vinifera]  1007   0.0  
ref|XP_002308967.1| predicted protein [Populus trichocarpa] gi|2...   993   0.0  
ref|XP_002526728.1| catalytic, putative [Ricinus communis] gi|22...   991   0.0  

>emb|CBI29877.3| unnamed protein product [Vitis vinifera]
          Length = 822

 Score = 1025 bits (2650), Expect = 0.0
 Identities = 462/579 (79%), Positives = 518/579 (89%)
 Frame = -3

Query: 2144 GGPKLTDWAKADLDNIFTTNTSRPGWCNVDPLEAYASKVKFKEECDCKYDCHVGRFCEVP 1965
            G PKL DW KADLDNIFTTN S+PGWCNVDP EAYA K+++KEECDCKYDC +GRFCE+P
Sbjct: 243  GDPKLVDWTKADLDNIFTTNDSKPGWCNVDPTEAYALKMQYKEECDCKYDCLLGRFCEIP 302

Query: 1964 VLCSCINQCSGHGYCRGGFCQCHSDWYGTDCSIPSASSSVQEWPQWLRPATIHVPDNAHL 1785
            VLC+C+NQCSGHG+CRGGFCQCH  WYGTDCSIPS  SSV+EWP+WLRPA + VPD+ HL
Sbjct: 303  VLCTCVNQCSGHGHCRGGFCQCHRGWYGTDCSIPSVLSSVREWPRWLRPAHVEVPDDMHL 362

Query: 1784 TADHVNIDTVIEKKRPLIYVYDLPPEFNSHLLEGRHFRFECVNRIYIEPNATLWTDQLYG 1605
            +   VN+D V++KKRPLIYVYDLPPEFNS LLEGRHF+FECVNRIY + NAT WT+QLYG
Sbjct: 363  SGSLVNLDAVVKKKRPLIYVYDLPPEFNSLLLEGRHFKFECVNRIYDDRNATYWTEQLYG 422

Query: 1604 SQMALYESILASPFRTLNGEEADYFFVPVLDACIITRADDAPHISMKNHLGLRSSLTLEY 1425
            +QMA+YESILASP RTL+GEEAD+FFVPVLD+CII RADDAPH++M  H GLRSSLTLE+
Sbjct: 423  AQMAIYESILASPHRTLDGEEADFFFVPVLDSCIIVRADDAPHLNMHAHGGLRSSLTLEF 482

Query: 1424 YKKAYDHITEQYHYWNRSSGRDHIWFFSWDEGACYAPKEIWNSMMLVHWGNTNSKHNHST 1245
            YK AYDHI EQY +WNRSSGRDHIWFFSWDEGACYAPKEIW+SMMLVHWGNTNSKHNHST
Sbjct: 483  YKTAYDHIVEQYPFWNRSSGRDHIWFFSWDEGACYAPKEIWDSMMLVHWGNTNSKHNHST 542

Query: 1244 TAYWADNWDGIPSTRRGNHPCFDPEKDLVLPAWKVPDPGSLRLKLWSRPHKERKKLFYFN 1065
            TAYWADNWD + S RRGNHPCFDP KDLVLPAWK PD  SL  KLWSRP ++RK LFYFN
Sbjct: 543  TAYWADNWDSVSSDRRGNHPCFDPYKDLVLPAWKRPDVVSLSSKLWSRPREQRKTLFYFN 602

Query: 1064 GNLGPAYENGRPEATYSMGIRQKLAEEFGSSPDKEGKLGKQHTEDVIVTPLRSNNYYEDL 885
            GNLGPAYE GRPE TYSMGIRQK+AEEFGSSP+KEGKLGKQH EDVIVTPLRS NY+E L
Sbjct: 603  GNLGPAYEGGRPETTYSMGIRQKVAEEFGSSPNKEGKLGKQHAEDVIVTPLRSGNYHESL 662

Query: 884  ATSVFCGVLPGDGWSGRIEDSVLHGCIPVVIQDGIFLPYENMLNYESFAVRIREDEISNL 705
            A+SVFCGV+PGDGWSGR EDS+L GCIPVVIQDGIFLP+ENMLNYESFAVRIREDEI NL
Sbjct: 663  ASSVFCGVMPGDGWSGRFEDSILQGCIPVVIQDGIFLPFENMLNYESFAVRIREDEIPNL 722

Query: 704  TKILRGFNETEIEFMLANVQRIWQRFLYRDSVLLEAERQRSVYGHVADWAIEFLRLSEDD 525
             KILRG NETEIEF L NV++IWQRFLYRDS+LLEAERQ++ +G+V DWA++ L+LSEDD
Sbjct: 723  IKILRGMNETEIEFKLENVRKIWQRFLYRDSILLEAERQKTAFGNVEDWAVQLLQLSEDD 782

Query: 524  VFSTFIQVLHYKLHNEPWRQKLDHIPKDFGLAKECIRNT 408
            VF+T IQVLHYKLHN+PWRQ+L H+ KDFGLA+EC+  T
Sbjct: 783  VFATLIQVLHYKLHNDPWRQQLAHLKKDFGLAQECLIRT 821


>ref|XP_002277596.1| PREDICTED: uncharacterized protein LOC100267584 [Vitis vinifera]
          Length = 794

 Score = 1025 bits (2650), Expect = 0.0
 Identities = 462/579 (79%), Positives = 518/579 (89%)
 Frame = -3

Query: 2144 GGPKLTDWAKADLDNIFTTNTSRPGWCNVDPLEAYASKVKFKEECDCKYDCHVGRFCEVP 1965
            G PKL DW KADLDNIFTTN S+PGWCNVDP EAYA K+++KEECDCKYDC +GRFCE+P
Sbjct: 215  GDPKLVDWTKADLDNIFTTNDSKPGWCNVDPTEAYALKMQYKEECDCKYDCLLGRFCEIP 274

Query: 1964 VLCSCINQCSGHGYCRGGFCQCHSDWYGTDCSIPSASSSVQEWPQWLRPATIHVPDNAHL 1785
            VLC+C+NQCSGHG+CRGGFCQCH  WYGTDCSIPS  SSV+EWP+WLRPA + VPD+ HL
Sbjct: 275  VLCTCVNQCSGHGHCRGGFCQCHRGWYGTDCSIPSVLSSVREWPRWLRPAHVEVPDDMHL 334

Query: 1784 TADHVNIDTVIEKKRPLIYVYDLPPEFNSHLLEGRHFRFECVNRIYIEPNATLWTDQLYG 1605
            +   VN+D V++KKRPLIYVYDLPPEFNS LLEGRHF+FECVNRIY + NAT WT+QLYG
Sbjct: 335  SGSLVNLDAVVKKKRPLIYVYDLPPEFNSLLLEGRHFKFECVNRIYDDRNATYWTEQLYG 394

Query: 1604 SQMALYESILASPFRTLNGEEADYFFVPVLDACIITRADDAPHISMKNHLGLRSSLTLEY 1425
            +QMA+YESILASP RTL+GEEAD+FFVPVLD+CII RADDAPH++M  H GLRSSLTLE+
Sbjct: 395  AQMAIYESILASPHRTLDGEEADFFFVPVLDSCIIVRADDAPHLNMHAHGGLRSSLTLEF 454

Query: 1424 YKKAYDHITEQYHYWNRSSGRDHIWFFSWDEGACYAPKEIWNSMMLVHWGNTNSKHNHST 1245
            YK AYDHI EQY +WNRSSGRDHIWFFSWDEGACYAPKEIW+SMMLVHWGNTNSKHNHST
Sbjct: 455  YKTAYDHIVEQYPFWNRSSGRDHIWFFSWDEGACYAPKEIWDSMMLVHWGNTNSKHNHST 514

Query: 1244 TAYWADNWDGIPSTRRGNHPCFDPEKDLVLPAWKVPDPGSLRLKLWSRPHKERKKLFYFN 1065
            TAYWADNWD + S RRGNHPCFDP KDLVLPAWK PD  SL  KLWSRP ++RK LFYFN
Sbjct: 515  TAYWADNWDSVSSDRRGNHPCFDPYKDLVLPAWKRPDVVSLSSKLWSRPREQRKTLFYFN 574

Query: 1064 GNLGPAYENGRPEATYSMGIRQKLAEEFGSSPDKEGKLGKQHTEDVIVTPLRSNNYYEDL 885
            GNLGPAYE GRPE TYSMGIRQK+AEEFGSSP+KEGKLGKQH EDVIVTPLRS NY+E L
Sbjct: 575  GNLGPAYEGGRPETTYSMGIRQKVAEEFGSSPNKEGKLGKQHAEDVIVTPLRSGNYHESL 634

Query: 884  ATSVFCGVLPGDGWSGRIEDSVLHGCIPVVIQDGIFLPYENMLNYESFAVRIREDEISNL 705
            A+SVFCGV+PGDGWSGR EDS+L GCIPVVIQDGIFLP+ENMLNYESFAVRIREDEI NL
Sbjct: 635  ASSVFCGVMPGDGWSGRFEDSILQGCIPVVIQDGIFLPFENMLNYESFAVRIREDEIPNL 694

Query: 704  TKILRGFNETEIEFMLANVQRIWQRFLYRDSVLLEAERQRSVYGHVADWAIEFLRLSEDD 525
             KILRG NETEIEF L NV++IWQRFLYRDS+LLEAERQ++ +G+V DWA++ L+LSEDD
Sbjct: 695  IKILRGMNETEIEFKLENVRKIWQRFLYRDSILLEAERQKTAFGNVEDWAVQLLQLSEDD 754

Query: 524  VFSTFIQVLHYKLHNEPWRQKLDHIPKDFGLAKECIRNT 408
            VF+T IQVLHYKLHN+PWRQ+L H+ KDFGLA+EC+  T
Sbjct: 755  VFATLIQVLHYKLHNDPWRQQLAHLKKDFGLAQECLIRT 793


>emb|CAN80640.1| hypothetical protein VITISV_016911 [Vitis vinifera]
          Length = 1363

 Score = 1007 bits (2603), Expect = 0.0
 Identities = 457/579 (78%), Positives = 511/579 (88%), Gaps = 9/579 (1%)
 Frame = -3

Query: 2144 GGPKLTDWAKADLDNIFTTNTSRPGWCNVDPLEAYASKVKFKEECDCKYDCHVGRFCEVP 1965
            G PKL DW KADLDNIFTTN S+PGWCNVDP EAYA K+++KEECDCKYDC +GRFCE+P
Sbjct: 231  GDPKLVDWTKADLDNIFTTNDSKPGWCNVDPTEAYALKMQYKEECDCKYDCLLGRFCEIP 290

Query: 1964 VLCSCINQCSGHGYCRGGFCQCHSDWYGTDCSIPSASSSVQEWPQWLRPATIHVPDNAHL 1785
            VLC+C+NQCSGHG+CRGGFCQCH  WYGTDCSIPS  SSV+EWP+WLRPA + VPD+ HL
Sbjct: 291  VLCTCVNQCSGHGHCRGGFCQCHRGWYGTDCSIPSVLSSVREWPRWLRPAHVEVPDDMHL 350

Query: 1784 TADHVNIDTVIEKKRPLIYVYDLPPEFNSHLLEGRHFRFECVNRIYIEPNATLWTDQLYG 1605
            +   VN+D V++KKRPLIYVYDLPPEFNS LLEGRHF+FECVNRIY + NAT WT+QLYG
Sbjct: 351  SGSLVNLDAVVKKKRPLIYVYDLPPEFNSLLLEGRHFKFECVNRIYDDRNATYWTEQLYG 410

Query: 1604 SQMALYESILASPFRTLNGEEADYFFVPVLDACIITRADDAPHISMKNHLGLRSSLTLEY 1425
            +QMA+YESILASP RTL+GEEAD+FFVPVLD+CII RADDAPH++M  H GLRSSLTLE+
Sbjct: 411  AQMAIYESILASPHRTLDGEEADFFFVPVLDSCIIVRADDAPHLNMHAHGGLRSSLTLEF 470

Query: 1424 YKKAYDHITEQYHYWNRSSGRDHIWFFSWDEGACYAPKEIWNSMMLVHWGNTNSKHNHST 1245
            YK AYDHI EQY +WNRSSGRDHIWFFSWDEGACYAPKEIW+SMMLVHWGNTNSKHNHST
Sbjct: 471  YKTAYDHIVEQYPFWNRSSGRDHIWFFSWDEGACYAPKEIWDSMMLVHWGNTNSKHNHST 530

Query: 1244 TAYWADNWDGIPSTRRGNHPCFDPEKDLVLPAWKVPDPGSLRLKLWSRPHKERKKLFYFN 1065
            TAYWADNWD + S RRGNHPCFDP KDLVLPAWK PD  SL  KLWSRP ++RK LFYFN
Sbjct: 531  TAYWADNWDSVSSDRRGNHPCFDPYKDLVLPAWKRPDVVSLSSKLWSRPREQRKTLFYFN 590

Query: 1064 GNLGPAYENGRPEATYSMGIRQKLAEEFGSSPDKEGKLGKQHTEDVIVTPLRSNNYYEDL 885
            GNLGPAYE GRPE TYSMGIRQK+AEEFGSSP+KEGKLGKQH EDVIVTPLRS NY+E L
Sbjct: 591  GNLGPAYEGGRPETTYSMGIRQKVAEEFGSSPNKEGKLGKQHAEDVIVTPLRSGNYHESL 650

Query: 884  ATSVFCGVLPGDGWSGRIEDSVLHGCIPVVIQDGIFLPYENMLNYESFAVRIREDEISNL 705
            A+SVFCGV+PGDGWSGR EDS+L GCIPVVIQDGIFLP+ENMLNYESFAVRIREDEI NL
Sbjct: 651  ASSVFCGVMPGDGWSGRFEDSILQGCIPVVIQDGIFLPFENMLNYESFAVRIREDEIPNL 710

Query: 704  TKILR---------GFNETEIEFMLANVQRIWQRFLYRDSVLLEAERQRSVYGHVADWAI 552
             KILR         G NETEIEF L NV++IWQRFLYRDS+LLEAERQ++ +G+V DWA+
Sbjct: 711  IKILRLSGDPYVLQGMNETEIEFKLENVRKIWQRFLYRDSILLEAERQKTAFGNVEDWAV 770

Query: 551  EFLRLSEDDVFSTFIQVLHYKLHNEPWRQKLDHIPKDFG 435
            + L+LSEDDVF+T IQVLHYKLHN+PWRQ+L H+ KDFG
Sbjct: 771  QLLQLSEDDVFATLIQVLHYKLHNDPWRQQLAHLKKDFG 809


>ref|XP_002308967.1| predicted protein [Populus trichocarpa] gi|222854943|gb|EEE92490.1|
            predicted protein [Populus trichocarpa]
          Length = 793

 Score =  993 bits (2566), Expect = 0.0
 Identities = 450/580 (77%), Positives = 517/580 (89%)
 Frame = -3

Query: 2144 GGPKLTDWAKADLDNIFTTNTSRPGWCNVDPLEAYASKVKFKEECDCKYDCHVGRFCEVP 1965
            G P+  DWAK DLD I+TTN S+ GWCNVDP E YA+KVKFKEECDCKYDC  GRFCEVP
Sbjct: 215  GAPRQVDWAKPDLD-IYTTNKSKLGWCNVDPAEGYANKVKFKEECDCKYDCLSGRFCEVP 273

Query: 1964 VLCSCINQCSGHGYCRGGFCQCHSDWYGTDCSIPSASSSVQEWPQWLRPATIHVPDNAHL 1785
            V CSCINQCSGHG+CRGGFCQC + WYGTDCSIPS +SSV+EWP+WLRPA + VPDNAHL
Sbjct: 274  VQCSCINQCSGHGHCRGGFCQCANGWYGTDCSIPSVTSSVREWPRWLRPAQLDVPDNAHL 333

Query: 1784 TADHVNIDTVIEKKRPLIYVYDLPPEFNSHLLEGRHFRFECVNRIYIEPNATLWTDQLYG 1605
            T   V+++ V++KKRPLIY+YDLPP+FNS LLEGRHF+FECVNR+Y + NAT+WTDQLYG
Sbjct: 334  TGKLVDLNAVVKKKRPLIYIYDLPPKFNSLLLEGRHFKFECVNRLYNDNNATIWTDQLYG 393

Query: 1604 SQMALYESILASPFRTLNGEEADYFFVPVLDACIITRADDAPHISMKNHLGLRSSLTLEY 1425
            +QMALYESILASP+RTLNGEEAD+FFVPVLD+CIITRADDAPH+SM+ HLGLRSSLTLE+
Sbjct: 394  AQMALYESILASPYRTLNGEEADFFFVPVLDSCIITRADDAPHLSMEQHLGLRSSLTLEF 453

Query: 1424 YKKAYDHITEQYHYWNRSSGRDHIWFFSWDEGACYAPKEIWNSMMLVHWGNTNSKHNHST 1245
            Y+KAYDHI E Y +WNRSSGRDH+W FSWDEGACYAPKEIWNSMM+VHWGNTNSKHNHST
Sbjct: 454  YRKAYDHIVEHYPFWNRSSGRDHLWSFSWDEGACYAPKEIWNSMMVVHWGNTNSKHNHST 513

Query: 1244 TAYWADNWDGIPSTRRGNHPCFDPEKDLVLPAWKVPDPGSLRLKLWSRPHKERKKLFYFN 1065
            TAYWADNWD I S RRG HPCFDP+KDLVLPAWK PD  +L  KLW+RP ++RK LFYFN
Sbjct: 514  TAYWADNWDKISSDRRGKHPCFDPDKDLVLPAWKRPDVNALSTKLWARPLEKRKTLFYFN 573

Query: 1064 GNLGPAYENGRPEATYSMGIRQKLAEEFGSSPDKEGKLGKQHTEDVIVTPLRSNNYYEDL 885
            GNLGPAY NGRPEA YSMGIRQKLAEEFGS+P+K+G LGKQH E+VIV+PLRS +Y+EDL
Sbjct: 574  GNLGPAYLNGRPEALYSMGIRQKLAEEFGSTPNKDGNLGKQHAENVIVSPLRSESYHEDL 633

Query: 884  ATSVFCGVLPGDGWSGRIEDSVLHGCIPVVIQDGIFLPYENMLNYESFAVRIREDEISNL 705
            A+SVFCGV+PGDGWSGR+EDS+L GCIPVVIQDGI+LPYEN+LNYESFAVRI EDEI NL
Sbjct: 634  ASSVFCGVMPGDGWSGRMEDSILQGCIPVVIQDGIYLPYENVLNYESFAVRILEDEIPNL 693

Query: 704  TKILRGFNETEIEFMLANVQRIWQRFLYRDSVLLEAERQRSVYGHVADWAIEFLRLSEDD 525
             KIL+GFNETEIE  L +VQ+I QRFLYRDS+LLEAERQ++ +G+V DWA+EFLRL+EDD
Sbjct: 694  IKILQGFNETEIENKLTSVQKIGQRFLYRDSMLLEAERQKTAFGYVEDWAVEFLRLTEDD 753

Query: 524  VFSTFIQVLHYKLHNEPWRQKLDHIPKDFGLAKECIRNTS 405
            V +TF+QVLHYKLHN+PWR++L    KDFGL +EC+  TS
Sbjct: 754  VVATFVQVLHYKLHNDPWRRQLGSQKKDFGLPQECLMRTS 793


>ref|XP_002526728.1| catalytic, putative [Ricinus communis] gi|223533917|gb|EEF35642.1|
            catalytic, putative [Ricinus communis]
          Length = 728

 Score =  991 bits (2563), Expect = 0.0
 Identities = 451/578 (78%), Positives = 506/578 (87%)
 Frame = -3

Query: 2147 NGGPKLTDWAKADLDNIFTTNTSRPGWCNVDPLEAYASKVKFKEECDCKYDCHVGRFCEV 1968
            +GGPKLTDW KADLDNIFTTN S+ GWCNVDP EAYASKVKFKEECDCKYD   GRFCEV
Sbjct: 163  SGGPKLTDWGKADLDNIFTTNKSKLGWCNVDPHEAYASKVKFKEECDCKYDGLFGRFCEV 222

Query: 1967 PVLCSCINQCSGHGYCRGGFCQCHSDWYGTDCSIPSASSSVQEWPQWLRPATIHVPDNAH 1788
            PV   CINQCSGHGYCRGGFCQC + WYGTDCSIPS  SSV EWPQWLRPA + VPDN+H
Sbjct: 223  PVQSICINQCSGHGYCRGGFCQCDNGWYGTDCSIPSVVSSVSEWPQWLRPALLDVPDNSH 282

Query: 1787 LTADHVNIDTVIEKKRPLIYVYDLPPEFNSHLLEGRHFRFECVNRIYIEPNATLWTDQLY 1608
            +    VN++ V+EKKRPLIY              GRHF+FECVNRIY   NAT+WTD LY
Sbjct: 283  VIQKLVNLNAVVEKKRPLIY--------------GRHFKFECVNRIYDGRNATIWTDHLY 328

Query: 1607 GSQMALYESILASPFRTLNGEEADYFFVPVLDACIITRADDAPHISMKNHLGLRSSLTLE 1428
            G+QMALYES+LASP+RTLNGEEAD+FFVP+LD+CIITRADDAPH+SM++H+GLRSSLTLE
Sbjct: 329  GAQMALYESLLASPYRTLNGEEADFFFVPILDSCIITRADDAPHLSMQDHMGLRSSLTLE 388

Query: 1427 YYKKAYDHITEQYHYWNRSSGRDHIWFFSWDEGACYAPKEIWNSMMLVHWGNTNSKHNHS 1248
            YY+KAYDHI E Y YWNR+SGRDHIWFFSWDEGACYAPKEIWNSMMLVHWGNTNSKHNHS
Sbjct: 389  YYRKAYDHIVEHYPYWNRTSGRDHIWFFSWDEGACYAPKEIWNSMMLVHWGNTNSKHNHS 448

Query: 1247 TTAYWADNWDGIPSTRRGNHPCFDPEKDLVLPAWKVPDPGSLRLKLWSRPHKERKKLFYF 1068
            TTAYWADNWD I S RRG HPCFDP+KDLVLPAWK PD  +L  KLW+RP + RK LF+F
Sbjct: 449  TTAYWADNWDKISSDRRGRHPCFDPDKDLVLPAWKRPDVSALSTKLWARPLERRKTLFFF 508

Query: 1067 NGNLGPAYENGRPEATYSMGIRQKLAEEFGSSPDKEGKLGKQHTEDVIVTPLRSNNYYED 888
            NGNLGPAY NGRPE +YSMGIRQKLAEEFGSSP+K+GKLGKQH EDVIVTPLRS NY+ED
Sbjct: 509  NGNLGPAYPNGRPELSYSMGIRQKLAEEFGSSPNKDGKLGKQHAEDVIVTPLRSENYHED 568

Query: 887  LATSVFCGVLPGDGWSGRIEDSVLHGCIPVVIQDGIFLPYENMLNYESFAVRIREDEISN 708
            LA+S+FCGVLPGDGWSGR+EDS+L GCIPV+IQDGIFLPYEN+LNYESFAVRIREDEISN
Sbjct: 569  LASSIFCGVLPGDGWSGRMEDSILQGCIPVIIQDGIFLPYENVLNYESFAVRIREDEISN 628

Query: 707  LTKILRGFNETEIEFMLANVQRIWQRFLYRDSVLLEAERQRSVYGHVADWAIEFLRLSED 528
            L KILRGFNETE EF LANV++IWQRFLYRD+VLLEA+RQ++ +GH  DW +EFL+L  D
Sbjct: 629  LLKILRGFNETEKEFKLANVRKIWQRFLYRDTVLLEAKRQKTAFGHEEDWEVEFLQLVND 688

Query: 527  DVFSTFIQVLHYKLHNEPWRQKLDHIPKDFGLAKECIR 414
            DVF+TFIQ+LHYKLHN+PWR++L H+ KDFGL +EC+R
Sbjct: 689  DVFTTFIQILHYKLHNDPWRRQLSHLKKDFGLPQECLR 726