BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Coptis23_contig00008006
         (3289 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002283993.1| PREDICTED: zinc-metallopeptidase, peroxisoma...   894   0.0  
ref|XP_002308028.1| predicted protein [Populus trichocarpa] gi|2...   858   0.0  
ref|XP_002283970.1| PREDICTED: zinc-metallopeptidase, peroxisoma...   844   0.0  
ref|XP_002532073.1| Insulin-degrading enzyme, putative [Ricinus ...   833   0.0  
ref|NP_001233926.1| insulin degrading enzyme [Solanum lycopersic...   831   0.0  

>ref|XP_002283993.1| PREDICTED: zinc-metallopeptidase, peroxisomal [Vitis vinifera]
            gi|297739661|emb|CBI29843.3| unnamed protein product
            [Vitis vinifera]
          Length = 965

 Score =  894 bits (2309), Expect(2) = 0.0
 Identities = 431/596 (72%), Positives = 506/596 (84%), Gaps = 2/596 (0%)
 Frame = +3

Query: 1137 AICETVFHYQDKVRPIDYVVNVASNMQIYPPEDWLVASSLPSKFSPETVQMILDELSPSN 1316
            AICETVFHYQDK+ PIDYVVNV+SNM++YPP+DWLV SSLPSKFSP+ +Q +LDEL+P+N
Sbjct: 370  AICETVFHYQDKIPPIDYVVNVSSNMELYPPKDWLVGSSLPSKFSPDVIQKVLDELAPNN 429

Query: 1317 VRIFWESQKFEGHTDMVEPWYGTAYTIQKITDSVIQQWIVKAPDELLHLPAANVFIPTDL 1496
            VRIFWES+ FEGHTDMVEPWYGTAY+I+KIT S+IQQW++ AP+E LHLP+ NVFIPTDL
Sbjct: 430  VRIFWESKNFEGHTDMVEPWYGTAYSIEKITSSMIQQWMLAAPNEHLHLPSPNVFIPTDL 489

Query: 1497 SLKDVQDKAKFPVLLRQSSYSRLWYKPDATFSSPKAYVNIDFICPYASHSPEAVVLTEIF 1676
            SLKDVQ+KAKFPVLLR+SSYS LWYKPD  FS+PKAYV IDF CP+AS SPEA VLT+IF
Sbjct: 490  SLKDVQEKAKFPVLLRKSSYSTLWYKPDTMFSTPKAYVKIDFNCPFASSSPEADVLTDIF 549

Query: 1677 VRLLMDYLNEYAYDAQVAGLYYGINQADTGFQVIVLGYNHKLRILVDTVVDQIADFEVKA 1856
             RLLMDYLNEYAY AQVAGLYYGIN  D+GFQV V GYNHKLRIL++TVV++IA+F+VK 
Sbjct: 550  TRLLMDYLNEYAYYAQVAGLYYGINHTDSGFQVAVTGYNHKLRILLETVVEKIANFKVKP 609

Query: 1857 DRFYVIKETVKKEYHNLKFQQPYQQAMYYCSLILEDQSWPWTEQLEVLPHLEADDXXXXX 2036
            DRF VIKE V KEY N KFQQPYQQAMYYCSLIL+D +WPW + LEV+PHLEADD     
Sbjct: 610  DRFLVIKEMVTKEYQNFKFQQPYQQAMYYCSLILQDNTWPWMDGLEVIPHLEADDLAKFV 669

Query: 2037 XXXXXXXXXXXYVAGNMEPKEAEAMLCHIEDTFFKGPKPISRVLLPSEHLTNRIVKLEKG 2216
                       Y+AGN+EPKEAE+M+ HIED F+ GP PIS+ L PS++LTNR++KL++G
Sbjct: 670  PMLLSRAFLDCYIAGNIEPKEAESMIHHIEDIFYSGPHPISQPLFPSQYLTNRVIKLDRG 729

Query: 2217 ICHFYQCQVLNKDEENSALVHYVQVHRDDFMLNVKLQLFALIAKQPAFHQLRSVEQLGYI 2396
            + +FY  + LN  +ENSALVHY+QVHRDDF+ NVKLQLFALIAKQ AFHQLRSVEQLGYI
Sbjct: 730  MSYFYPAEGLNPSDENSALVHYIQVHRDDFLPNVKLQLFALIAKQRAFHQLRSVEQLGYI 789

Query: 2397 TVLMQRYNSGIRGLQFIVQSTVKDPGHINMRVEAFLKDFETKLYELSDNEFRSNVNALID 2576
            TVLMQR +SGIRG+QFI+QSTVK PGHI+ RV  FLK FE+KLY +S++EF+SNVNALID
Sbjct: 790  TVLMQRNDSGIRGVQFIIQSTVKGPGHIDSRVVEFLKMFESKLYAMSEDEFKSNVNALID 849

Query: 2577 MKLEKPKNLREESSFYWREIADGTLKFDRKDAEVAALKCLTKEDLISFFEEHVKVDAPHR 2756
            MKLEK KNLREES FYWREI DGTLKFDR++AEVAALK LT+++LI FF EH+KV AP +
Sbjct: 850  MKLEKHKNLREESGFYWREIYDGTLKFDRREAEVAALKKLTQKELIDFFNEHIKVGAPQK 909

Query: 2757 KTLAIQVYGSLHSSEYKAAKSET--PLSVQINDIFSFRRSQSLYGSFKGGLGHTKL 2918
            KTL+++VYG LH+SEY   K E   P  V+I+DIF FR+SQ LYGSFKGGLG  KL
Sbjct: 910  KTLSVRVYGGLHTSEYADEKKEANQPKQVKIDDIFKFRKSQPLYGSFKGGLGQVKL 965



 Score =  623 bits (1607), Expect(2) = 0.0
 Identities = 297/360 (82%), Positives = 327/360 (90%)
 Frame = +1

Query: 58   IIKPRTDKREYRRIVLPNALQVLLISDPETDKAAASMNVSVGYYSDPEGLEGLAHFLEHM 237
            I+KPRTD REYRRIVL N+L+VLLISDP+TDKAAASM+VSVG + DPEG  GLAHFLEHM
Sbjct: 8    IVKPRTDTREYRRIVLRNSLEVLLISDPDTDKAAASMSVSVGSFCDPEGFPGLAHFLEHM 67

Query: 238  LFYASEKYPLEDSYSKYITEHGGSTNAFTSSEQTNYYFDINPNSFEEALDRFSQFFIKPL 417
            LFYASEKYPLEDSYSKYI EHGGSTNAFTSSE TNYYFD+N + FEEALDRF+QFF+KPL
Sbjct: 68   LFYASEKYPLEDSYSKYIIEHGGSTNAFTSSEHTNYYFDVNSDCFEEALDRFAQFFVKPL 127

Query: 418  MSSDATTREIKAVDSENQKNLLSDGWRMSQLQKHLSAEAHPYHKFSTGNWDTLEVRPKEK 597
            MS+DATTREIKAVDSENQKNLLSD WRM QLQKH+SAE HPYHKFSTGNWDTLEV+PKEK
Sbjct: 128  MSADATTREIKAVDSENQKNLLSDAWRMCQLQKHISAEGHPYHKFSTGNWDTLEVKPKEK 187

Query: 598  GIDTRDRLIKFYEENYSANLMHLVVYGKESLNEMQSLVGCKFQDISNADRNCFHCPGQPC 777
            G+DTR  LIKFYEE+YSANLMHLVVY KESL+++QSLV  KFQ+I N DR+ F  PGQPC
Sbjct: 188  GLDTRHELIKFYEEHYSANLMHLVVYTKESLDKIQSLVEHKFQEIQNKDRSNFQIPGQPC 247

Query: 778  MPEHLQIIVKAVPVKQGHKLRVIWPITPSIRHYKESPCRYLGHLIGHEGEGSLFYVLKKL 957
              EHLQI+VK VP+KQGHKLRVIWPITPSI +YKE PCRYLGHLIGHEGEGSLFY+LK L
Sbjct: 248  TSEHLQILVKTVPIKQGHKLRVIWPITPSIHNYKEGPCRYLGHLIGHEGEGSLFYILKTL 307

Query: 958  GWATSLSAGEGDWTYEFSFFKVSIDLTDAGHDHMEDIVGLLFKYVLLLQQSGVKEWIFDE 1137
            GWATSLSAGEGDWT EFSFFKV IDLT+AGH+HM+DIVGLLFKY+ LLQQ+GV +WIFDE
Sbjct: 308  GWATSLSAGEGDWTCEFSFFKVVIDLTEAGHEHMQDIVGLLFKYISLLQQTGVCKWIFDE 367


>ref|XP_002308028.1| predicted protein [Populus trichocarpa] gi|222854004|gb|EEE91551.1|
            predicted protein [Populus trichocarpa]
          Length = 949

 Score =  858 bits (2217), Expect(2) = 0.0
 Identities = 416/596 (69%), Positives = 496/596 (83%), Gaps = 2/596 (0%)
 Frame = +3

Query: 1137 AICETVFHYQDKVRPIDYVVNVASNMQIYPPEDWLVASSLPSKFSPETVQMILDELSPSN 1316
            AICET FHYQDK  PI YVV +ASNMQ+YP +DWLV SSLPS FSP  +Q +L++LSP N
Sbjct: 354  AICETSFHYQDKTPPISYVVRIASNMQLYPQKDWLVGSSLPSNFSPSIIQTVLNQLSPDN 413

Query: 1317 VRIFWESQKFEGHTDMVEPWYGTAYTIQKITDSVIQQWIVKAPDELLHLPAANVFIPTDL 1496
            VRIFWES+KFEG T M EPWY TAY+++KIT S+IQ+W++ AP+E LHLPA NVFIPTDL
Sbjct: 414  VRIFWESKKFEGQTAMTEPWYKTAYSVEKITGSMIQEWMLFAPNEDLHLPAPNVFIPTDL 473

Query: 1497 SLKDVQDKAKFPVLLRQSSYSRLWYKPDATFSSPKAYVNIDFICPYASHSPEAVVLTEIF 1676
            SLKD Q+K KFPVLLR+SS S LWYKPD  FS+PKAYV IDF CP+AS SPE  VLT+IF
Sbjct: 474  SLKDAQEKVKFPVLLRKSSSSSLWYKPDTMFSTPKAYVKIDFNCPFASSSPETEVLTDIF 533

Query: 1677 VRLLMDYLNEYAYDAQVAGLYYGINQADTGFQVIVLGYNHKLRILVDTVVDQIADFEVKA 1856
             RLLMD LN+YAY AQVAGLYYGI+  D+GFQV V+GYNHKLRIL++TV+++I++F+VK 
Sbjct: 534  ARLLMDDLNDYAYYAQVAGLYYGISNTDSGFQVTVVGYNHKLRILLETVIEKISNFKVKP 593

Query: 1857 DRFYVIKETVKKEYHNLKFQQPYQQAMYYCSLILEDQSWPWTEQLEVLPHLEADDXXXXX 2036
            DRF VIKE V KEY NLKFQQPYQQAMYYCSL+L+DQ+WPW EQLE+LPHL+A+D     
Sbjct: 594  DRFSVIKEMVTKEYGNLKFQQPYQQAMYYCSLLLQDQTWPWMEQLEILPHLQAEDLAKFI 653

Query: 2037 XXXXXXXXXXXYVAGNMEPKEAEAMLCHIEDTFFKGPKPISRVLLPSEHLTNRIVKLEKG 2216
                       Y+AGN+E  EAE+M+ HIED F +GP PI + L PS+HLT+R++KLE+G
Sbjct: 654  PLMLSRAFLECYIAGNIERSEAESMILHIEDVFNEGPDPICQPLFPSQHLTSRVIKLERG 713

Query: 2217 ICHFYQCQVLNKDEENSALVHYVQVHRDDFMLNVKLQLFALIAKQPAFHQLRSVEQLGYI 2396
            I + Y  + LN D+ENSALVHY+Q+HRDDF  NVKLQL ALIAKQPAFHQLRSVEQLGYI
Sbjct: 714  INYLYPIEGLNPDDENSALVHYIQIHRDDFTWNVKLQLLALIAKQPAFHQLRSVEQLGYI 773

Query: 2397 TVLMQRYNSGIRGLQFIVQSTVKDPGHINMRVEAFLKDFETKLYELSDNEFRSNVNALID 2576
            TVLMQR +SGIRGLQFI+QSTVK PG I++RVEAFLK FETKLY ++++EF+SNVNALID
Sbjct: 774  TVLMQRNDSGIRGLQFIIQSTVKGPGQIDLRVEAFLKMFETKLYGMTNDEFKSNVNALID 833

Query: 2577 MKLEKPKNLREESSFYWREIADGTLKFDRKDAEVAALKCLTKEDLISFFEEHVKVDAPHR 2756
            MKLEK KNLREES+F+WREI+DGTLKFDR++ EVAALK LT++DLI FF+EHVKV AP +
Sbjct: 834  MKLEKHKNLREESAFFWREISDGTLKFDRRECEVAALKQLTQQDLIDFFDEHVKVGAPRK 893

Query: 2757 KTLAIQVYGSLHSSEYKAAKSE--TPLSVQINDIFSFRRSQSLYGSFKGGLGHTKL 2918
            +TL+++VYG LHS EY + KS+   P +VQI DIFSFRRSQ LYGSFKGG GH KL
Sbjct: 894  RTLSVRVYGKLHSCEYPSDKSQQLPPNAVQIEDIFSFRRSQPLYGSFKGGFGHMKL 949



 Score =  578 bits (1491), Expect(2) = 0.0
 Identities = 277/360 (76%), Positives = 313/360 (86%)
 Frame = +1

Query: 58   IIKPRTDKREYRRIVLPNALQVLLISDPETDKAAASMNVSVGYYSDPEGLEGLAHFLEHM 237
            I+K RTDKREY+RIVLPNALQ            AASMNVSVG +SDP+GLEGLAHFLEHM
Sbjct: 3    IVKARTDKREYKRIVLPNALQ-----------CAASMNVSVGCFSDPDGLEGLAHFLEHM 51

Query: 238  LFYASEKYPLEDSYSKYITEHGGSTNAFTSSEQTNYYFDINPNSFEEALDRFSQFFIKPL 417
            LFYASEKYPLEDSYSKYI EHGGSTNA+T+S+ TNY+FD+N + FE+ALDRF+QFFIKPL
Sbjct: 52   LFYASEKYPLEDSYSKYIIEHGGSTNAYTTSDHTNYHFDVNSDCFEDALDRFAQFFIKPL 111

Query: 418  MSSDATTREIKAVDSENQKNLLSDGWRMSQLQKHLSAEAHPYHKFSTGNWDTLEVRPKEK 597
            MS+DAT REIKAVDSENQKNLLSDGWR++QLQKHLS E HPYHKFSTGNWDTLEV+PKEK
Sbjct: 112  MSADATVREIKAVDSENQKNLLSDGWRINQLQKHLSEEGHPYHKFSTGNWDTLEVQPKEK 171

Query: 598  GIDTRDRLIKFYEENYSANLMHLVVYGKESLNEMQSLVGCKFQDISNADRNCFHCPGQPC 777
            G+DTR  LIK YEENYSANLM+LV+Y KESL+++QSLV  KFQ+I N DR+CF  PGQPC
Sbjct: 172  GLDTRLELIKLYEENYSANLMNLVIYAKESLDKIQSLVEEKFQEIRNNDRSCFSFPGQPC 231

Query: 778  MPEHLQIIVKAVPVKQGHKLRVIWPITPSIRHYKESPCRYLGHLIGHEGEGSLFYVLKKL 957
              EHLQI+V+ VP+KQGHKLR++WPITP I HYKE PCRYLGHLIGHEGEGSLFYVLK L
Sbjct: 232  SSEHLQILVRTVPIKQGHKLRIVWPITPGILHYKEGPCRYLGHLIGHEGEGSLFYVLKTL 291

Query: 958  GWATSLSAGEGDWTYEFSFFKVSIDLTDAGHDHMEDIVGLLFKYVLLLQQSGVKEWIFDE 1137
            GWAT LSAGE D T EF+FF   I+LTDAGH+HM+D+VGLLFKY+ LLQQSGV +WIFDE
Sbjct: 292  GWATDLSAGEVDGTTEFAFFTAVINLTDAGHEHMQDVVGLLFKYIHLLQQSGVCKWIFDE 351


>ref|XP_002283970.1| PREDICTED: zinc-metallopeptidase, peroxisomal [Vitis vinifera]
            gi|297739662|emb|CBI29844.3| unnamed protein product
            [Vitis vinifera]
          Length = 965

 Score =  844 bits (2181), Expect(2) = 0.0
 Identities = 409/596 (68%), Positives = 492/596 (82%), Gaps = 2/596 (0%)
 Frame = +3

Query: 1137 AICETVFHYQDKVRPIDYVVNVASNMQIYPPEDWLVASSLPSKFSPETVQMILDELSPSN 1316
            AICET+FHYQDK+  IDYVVNV+SNM++YPP+DWLV SSLPSKFSP+ +Q +LDEL+P+N
Sbjct: 370  AICETMFHYQDKIPSIDYVVNVSSNMELYPPKDWLVGSSLPSKFSPDVIQKVLDELAPNN 429

Query: 1317 VRIFWESQKFEGHTDMVEPWYGTAYTIQKITDSVIQQWIVKAPDELLHLPAANVFIPTDL 1496
            VRIFWES+ FEGHTDMVEPWYGTA++I+KIT S+IQQW++ AP E LHLP  N FIPTDL
Sbjct: 430  VRIFWESKNFEGHTDMVEPWYGTAFSIEKITVSMIQQWMLAAPTEHLHLPDPNDFIPTDL 489

Query: 1497 SLKDVQDKAKFPVLLRQSSYSRLWYKPDATFSSPKAYVNIDFICPYASHSPEAVVLTEIF 1676
            SLK+VQ+KAKFPVLLR+SSYS LWYKPD  FS+PKAYV IDF CP+AS SPEA VLT+IF
Sbjct: 490  SLKNVQEKAKFPVLLRKSSYSTLWYKPDTMFSTPKAYVKIDFNCPFASSSPEADVLTDIF 549

Query: 1677 VRLLMDYLNEYAYDAQVAGLYYGINQADTGFQVIVLGYNHKLRILVDTVVDQIADFEVKA 1856
             RLLMDYLNE AY A+VAGLYY ++  D+GFQV + GYNHKLRIL++TVV +IA+F+VK 
Sbjct: 550  TRLLMDYLNEDAYYAEVAGLYYCLSNTDSGFQVAMAGYNHKLRILLETVVKKIANFKVKP 609

Query: 1857 DRFYVIKETVKKEYHNLKFQQPYQQAMYYCSLILEDQSWPWTEQLEVLPHLEADDXXXXX 2036
            DRF VIKE V K Y N+KFQQPYQQAM Y SLIL D +WPW + LEV+PHLEADD     
Sbjct: 610  DRFLVIKELVTKGYQNVKFQQPYQQAMCYRSLILHDNTWPWMDGLEVIPHLEADDLAKFV 669

Query: 2037 XXXXXXXXXXXYVAGNMEPKEAEAMLCHIEDTFFKGPKPISRVLLPSEHLTNRIVKLEKG 2216
                       Y+AGN+EPKEAEAM+ HIED F+ GP+PI + L PS++LTNR++KL++G
Sbjct: 670  PMLLSRAFLECYIAGNIEPKEAEAMIHHIEDIFYSGPRPICQPLFPSQYLTNRVIKLDRG 729

Query: 2217 ICHFYQCQVLNKDEENSALVHYVQVHRDDFMLNVKLQLFALIAKQPAFHQLRSVEQLGYI 2396
            + +FY  + LN  +ENSALVHY+QVHRDDF+ NVKLQLFALIAKQ AFHQLRSVEQLGYI
Sbjct: 730  MSYFYPAEGLNPSDENSALVHYIQVHRDDFLPNVKLQLFALIAKQQAFHQLRSVEQLGYI 789

Query: 2397 TVLMQRYNSGIRGLQFIVQSTVKDPGHINMRVEAFLKDFETKLYELSDNEFRSNVNALID 2576
            T LM R +SGI G+QF++QSTVK PGHI+ R+E FLK FE KLY +S++EF+SNVN L+D
Sbjct: 790  TELMLRNDSGIHGVQFMIQSTVKGPGHIDSRIEEFLKMFEFKLYAMSEDEFKSNVNTLVD 849

Query: 2577 MKLEKPKNLREESSFYWREIADGTLKFDRKDAEVAALKCLTKEDLISFFEEHVKVDAPHR 2756
            MKLEK KNL EES FYW+EI DGTLKFDR +AEVAALK LT+++LI FF EH+KV AP +
Sbjct: 850  MKLEKYKNLWEESGFYWQEIYDGTLKFDRTEAEVAALKKLTQKELIDFFNEHIKVGAPQK 909

Query: 2757 KTLAIQVYGSLHSSEYKAAKSET--PLSVQINDIFSFRRSQSLYGSFKGGLGHTKL 2918
            KTL+++VYG LH+SEY   + E   P+ V+I+DIF FR+SQ LYGSFKGGLGH KL
Sbjct: 910  KTLSVRVYGCLHTSEYAEEQKEANQPIQVKIDDIFKFRKSQPLYGSFKGGLGHVKL 965



 Score =  603 bits (1554), Expect(2) = 0.0
 Identities = 289/360 (80%), Positives = 323/360 (89%)
 Frame = +1

Query: 58   IIKPRTDKREYRRIVLPNALQVLLISDPETDKAAASMNVSVGYYSDPEGLEGLAHFLEHM 237
            I+KPRTD REYRRIVL N+L+ LLISDP+TDKAAASM+VSVG +SDPEG  GLAHFLEHM
Sbjct: 8    IVKPRTDTREYRRIVLRNSLEALLISDPDTDKAAASMSVSVGSFSDPEGFPGLAHFLEHM 67

Query: 238  LFYASEKYPLEDSYSKYITEHGGSTNAFTSSEQTNYYFDINPNSFEEALDRFSQFFIKPL 417
            LFYASEKYPLEDSYSKYITEHGGSTNAFT+SE TNY+FD+N + FEEALDRF+QFF+KPL
Sbjct: 68   LFYASEKYPLEDSYSKYITEHGGSTNAFTASEHTNYFFDVNTDCFEEALDRFAQFFVKPL 127

Query: 418  MSSDATTREIKAVDSENQKNLLSDGWRMSQLQKHLSAEAHPYHKFSTGNWDTLEVRPKEK 597
            MS+DATTREIKAVDSEN+KNLLSD WRM QLQKH+SAE HPYHKFSTGN DTLEV+PKEK
Sbjct: 128  MSADATTREIKAVDSENKKNLLSDAWRMDQLQKHVSAEGHPYHKFSTGNRDTLEVKPKEK 187

Query: 598  GIDTRDRLIKFYEENYSANLMHLVVYGKESLNEMQSLVGCKFQDISNADRNCFHCPGQPC 777
            G+DTR  LIKFYEE+YSANLMHLVVY KESL+++QSLV  KFQ+I N DR  FH  GQPC
Sbjct: 188  GLDTRHELIKFYEEHYSANLMHLVVYTKESLDKIQSLVEHKFQEIQNKDRINFHICGQPC 247

Query: 778  MPEHLQIIVKAVPVKQGHKLRVIWPITPSIRHYKESPCRYLGHLIGHEGEGSLFYVLKKL 957
              EHLQI+VK VP+KQGHKL V+WPITPSI +YKE PCRYLGHLIGHEG+GSLFY+LK L
Sbjct: 248  TSEHLQILVKTVPIKQGHKLIVVWPITPSIHNYKEGPCRYLGHLIGHEGKGSLFYILKTL 307

Query: 958  GWATSLSAGEGDWTYEFSFFKVSIDLTDAGHDHMEDIVGLLFKYVLLLQQSGVKEWIFDE 1137
            GWATSLSA E DWT EFSFF+V IDLTDAGH+HM+DIVGLLFKY+ LLQQ+GV +WIFDE
Sbjct: 308  GWATSLSAWEEDWTCEFSFFEVVIDLTDAGHEHMQDIVGLLFKYISLLQQTGVCKWIFDE 367


>ref|XP_002532073.1| Insulin-degrading enzyme, putative [Ricinus communis]
            gi|223528255|gb|EEF30307.1| Insulin-degrading enzyme,
            putative [Ricinus communis]
          Length = 967

 Score =  833 bits (2153), Expect(2) = 0.0
 Identities = 401/596 (67%), Positives = 492/596 (82%), Gaps = 2/596 (0%)
 Frame = +3

Query: 1137 AICETVFHYQDKVRPIDYVVNVASNMQIYPPEDWLVASSLPSKFSPETVQMILDELSPSN 1316
            A+CET FHYQDK+ PIDYVV +A NM IYPP+DWLV SSLPS FSP+ +QM+L +LSP++
Sbjct: 372  AVCETSFHYQDKIPPIDYVVTIACNMNIYPPKDWLVGSSLPSNFSPDIIQMVLHQLSPNS 431

Query: 1317 VRIFWESQKFEGHTDMVEPWYGTAYTIQKITDSVIQQWIVKAPDELLHLPAANVFIPTDL 1496
            VRIFWES+ FEG T+ VEPWYGTAY+++KI   VIQ+W++ APDE LHLPA NVFIPTDL
Sbjct: 432  VRIFWESKNFEGQTEKVEPWYGTAYSVEKIDSLVIQEWMLSAPDENLHLPAPNVFIPTDL 491

Query: 1497 SLKDVQDKAKFPVLLRQSSYSRLWYKPDATFSSPKAYVNIDFICPYASHSPEAVVLTEIF 1676
            SLK  Q+K   PVLLR+SSYS LWYKPD  F++PKAYV IDF CP+A  SPEA VLT+IF
Sbjct: 492  SLKSAQEKVILPVLLRKSSYSSLWYKPDTMFNTPKAYVKIDFSCPHAGSSPEADVLTDIF 551

Query: 1677 VRLLMDYLNEYAYDAQVAGLYYGINQADTGFQVIVLGYNHKLRILVDTVVDQIADFEVKA 1856
             RLLMDYLNEYAY AQVAGLYYGI + D+GFQV ++GYNHKL+IL++TV+++IA F+V  
Sbjct: 552  ARLLMDYLNEYAYYAQVAGLYYGITKTDSGFQVTLVGYNHKLKILLETVIEKIAKFKVNP 611

Query: 1857 DRFYVIKETVKKEYHNLKFQQPYQQAMYYCSLILEDQSWPWTEQLEVLPHLEADDXXXXX 2036
            DRF VIKE V K+Y N KFQQPYQQA+YY SLIL++Q+WPW E+LEVLPHL A+D     
Sbjct: 612  DRFSVIKEMVIKKYKNFKFQQPYQQAIYYSSLILQNQAWPWMEELEVLPHLVAEDLAKFV 671

Query: 2037 XXXXXXXXXXXYVAGNMEPKEAEAMLCHIEDTFFKGPKPISRVLLPSEHLTNRIVKLEKG 2216
                       Y+AGN+E  EAE+++ HIE+ FFKG  PI + L PS+HLTNR++KL +G
Sbjct: 672  PIMLSRSFLECYIAGNIESIEAESIIEHIENVFFKGQNPICQPLFPSQHLTNRVMKLGRG 731

Query: 2217 ICHFYQCQVLNKDEENSALVHYVQVHRDDFMLNVKLQLFALIAKQPAFHQLRSVEQLGYI 2396
              +FY  + LN  +ENSALVHY+QVH+DDF+LNVKLQLFALIAKQPAFHQLRSVEQLGYI
Sbjct: 732  KSYFYAIEGLNPSDENSALVHYIQVHQDDFLLNVKLQLFALIAKQPAFHQLRSVEQLGYI 791

Query: 2397 TVLMQRYNSGIRGLQFIVQSTVKDPGHINMRVEAFLKDFETKLYELSDNEFRSNVNALID 2576
            TVLM R +SGIRG+ FI+QSTVK P HI++RVEAFLK FETKLYE++++EF++NVN+LID
Sbjct: 792  TVLMPRNDSGIRGVHFIIQSTVKGPVHIDLRVEAFLKSFETKLYEMTNDEFKNNVNSLID 851

Query: 2577 MKLEKPKNLREESSFYWREIADGTLKFDRKDAEVAALKCLTKEDLISFFEEHVKVDAPHR 2756
            MKLEK KNL EES FYWREIADGTLKFDR+D+EVAAL+ LT+++ + FF E++KV AP R
Sbjct: 852  MKLEKHKNLGEESGFYWREIADGTLKFDRRDSEVAALRQLTQQEFVDFFNENIKVGAPGR 911

Query: 2757 KTLAIQVYGSLHSSEYKAAKSET--PLSVQINDIFSFRRSQSLYGSFKGGLGHTKL 2918
            +TL+I+VYG+ HS+EY + KSE+  P S+QI+DIFSFRR+QSLYGS +GG GH KL
Sbjct: 912  RTLSIRVYGASHSAEYTSDKSESLLPNSIQIDDIFSFRRTQSLYGSCRGGFGHMKL 967



 Score =  624 bits (1608), Expect(2) = 0.0
 Identities = 295/360 (81%), Positives = 324/360 (90%)
 Frame = +1

Query: 58   IIKPRTDKREYRRIVLPNALQVLLISDPETDKAAASMNVSVGYYSDPEGLEGLAHFLEHM 237
            I+K RTDKREYRRIVL N+L+VLLISDPETDK AASM+VSVG++SDP GLEGLAHFLEHM
Sbjct: 10   IVKARTDKREYRRIVLRNSLEVLLISDPETDKCAASMDVSVGFFSDPAGLEGLAHFLEHM 69

Query: 238  LFYASEKYPLEDSYSKYITEHGGSTNAFTSSEQTNYYFDINPNSFEEALDRFSQFFIKPL 417
            LFYASEKYPLEDSYSKYITEHGGSTNAFTSSE TNYYFD+N + FE+ALDRF+QFFIKPL
Sbjct: 70   LFYASEKYPLEDSYSKYITEHGGSTNAFTSSEFTNYYFDVNTDCFEDALDRFAQFFIKPL 129

Query: 418  MSSDATTREIKAVDSENQKNLLSDGWRMSQLQKHLSAEAHPYHKFSTGNWDTLEVRPKEK 597
            MS+DAT REIKAVDSENQKNLLSD WRM QLQKHLS E HPYHKF TGNWDTLEVRPK K
Sbjct: 130  MSADATMREIKAVDSENQKNLLSDAWRMGQLQKHLSDEGHPYHKFGTGNWDTLEVRPKAK 189

Query: 598  GIDTRDRLIKFYEENYSANLMHLVVYGKESLNEMQSLVGCKFQDISNADRNCFHCPGQPC 777
            G+DTR+ LIKFYEENYSAN MHLV+Y KESL+++Q L+  KFQ I N DR+C   PGQPC
Sbjct: 190  GLDTRNELIKFYEENYSANRMHLVIYAKESLDKLQILIEDKFQHIRNKDRSCLSFPGQPC 249

Query: 778  MPEHLQIIVKAVPVKQGHKLRVIWPITPSIRHYKESPCRYLGHLIGHEGEGSLFYVLKKL 957
              EHLQI+VKAVP+KQGH+L++IWPITP I HYKE PCRYLGHLIGHEGEGSLFYVLK L
Sbjct: 250  SSEHLQILVKAVPIKQGHRLKIIWPITPEILHYKEGPCRYLGHLIGHEGEGSLFYVLKTL 309

Query: 958  GWATSLSAGEGDWTYEFSFFKVSIDLTDAGHDHMEDIVGLLFKYVLLLQQSGVKEWIFDE 1137
            GWATSLSAGEGDWT EFSFFKV IDLTDAGH+HM+DI+GLLFKY+ LLQQSGV EWIF+E
Sbjct: 310  GWATSLSAGEGDWTMEFSFFKVGIDLTDAGHEHMQDIIGLLFKYIHLLQQSGVSEWIFNE 369


>ref|NP_001233926.1| insulin degrading enzyme [Solanum lycopersicum]
            gi|15485612|emb|CAC67408.1| insulin degrading enzyme
            [Solanum lycopersicum]
          Length = 971

 Score =  831 bits (2146), Expect(2) = 0.0
 Identities = 399/596 (66%), Positives = 481/596 (80%), Gaps = 2/596 (0%)
 Frame = +3

Query: 1137 AICETVFHYQDKVRPIDYVVNVASNMQIYPPEDWLVASSLPSKFSPETVQMILDELSPSN 1316
            AICET FHYQDK+RP DYVVNVA NMQ YPPEDWLVASSLPSKF+P  +Q  L+EL+P N
Sbjct: 376  AICETAFHYQDKIRPSDYVVNVAMNMQHYPPEDWLVASSLPSKFNPSIIQSFLNELNPDN 435

Query: 1317 VRIFWESQKFEGHTDMVEPWYGTAYTIQKITDSVIQQWIVKAPDELLHLPAANVFIPTDL 1496
            VRIFWES KFEG+T M EPWYGTAY+I+K+    I+QW+  AP E LHLPA NVFIPTDL
Sbjct: 436  VRIFWESTKFEGNTSMTEPWYGTAYSIEKVGGDSIKQWMEHAPSEELHLPAPNVFIPTDL 495

Query: 1497 SLKDVQDKAKFPVLLRQSSYSRLWYKPDATFSSPKAYVNIDFICPYASHSPEAVVLTEIF 1676
            SLK V +K K P+LLR+S YSRLWYKPD  FSSPKAYV IDF CPY  HSPEA VLTEIF
Sbjct: 496  SLKPVFEKTKVPILLRKSPYSRLWYKPDTAFSSPKAYVMIDFSCPYCGHSPEAEVLTEIF 555

Query: 1677 VRLLMDYLNEYAYDAQVAGLYYGINQADTGFQVIVLGYNHKLRILVDTVVDQIADFEVKA 1856
             RLLMDYLNEYAY+AQVAGLYY I++ ++GFQ+ + GYN KLR+L++ V++++A FEVK 
Sbjct: 556  TRLLMDYLNEYAYNAQVAGLYYDISKTNSGFQLTLFGYNDKLRVLLEAVIEKVAKFEVKP 615

Query: 1857 DRFYVIKETVKKEYHNLKFQQPYQQAMYYCSLILEDQSWPWTEQLEVLPHLEADDXXXXX 2036
            DRF V+KE V K+Y N KFQQPYQQ MYYCSL+L+D  WPW E+L+VLPHL+ DD     
Sbjct: 616  DRFSVVKELVTKQYQNFKFQQPYQQVMYYCSLLLKDNIWPWNEELDVLPHLKVDDLVKFY 675

Query: 2037 XXXXXXXXXXXYVAGNMEPKEAEAMLCHIEDTFFKGPKPISRVLLPSEHLTNRIVKLEKG 2216
                       YVAGN+E  EAE+M+  IED FFKGP+ IS+ L  S+HLTNR+V LE+G
Sbjct: 676  PLLMARSFMECYVAGNVEQAEAESMIQLIEDVFFKGPQSISKPLFASQHLTNRVVNLERG 735

Query: 2217 ICHFYQCQVLNKDEENSALVHYVQVHRDDFMLNVKLQLFALIAKQPAFHQLRSVEQLGYI 2396
            + + Y  + LN  +ENSALVHY+QVH+DDFMLNVKLQLFALIAKQPAFHQLRSVEQLGYI
Sbjct: 736  VNYVYAAEGLNPSDENSALVHYIQVHQDDFMLNVKLQLFALIAKQPAFHQLRSVEQLGYI 795

Query: 2397 TVLMQRYNSGIRGLQFIVQSTVKDPGHINMRVEAFLKDFETKLYELSDNEFRSNVNALID 2576
            TVLMQR +SG+ G+QFIVQST KDP +I+ RVE F+K FE+KLYE++ +EF++NVNALID
Sbjct: 796  TVLMQRSDSGVHGVQFIVQSTAKDPKYIDTRVELFMKMFESKLYEMTSDEFKNNVNALID 855

Query: 2577 MKLEKPKNLREESSFYWREIADGTLKFDRKDAEVAALKCLTKEDLISFFEEHVKVDAPHR 2756
            MKLEK KNLREES FYWREI+DGTLKFDR+D E+ ALK LT+++L  FF+E++KV  P +
Sbjct: 856  MKLEKHKNLREESRFYWREISDGTLKFDRRDREIVALKQLTQKELTDFFDEYIKVGVPRK 915

Query: 2757 KTLAIQVYGSLHSSEYKAAKSE--TPLSVQINDIFSFRRSQSLYGSFKGGLGHTKL 2918
            K L+++VYGS HSS+++A K+E   P +VQI +IFSFRRS+ LY SFKGG GH +L
Sbjct: 916  KALSVRVYGSSHSSQFQAHKNEQMEPNAVQIEEIFSFRRSRPLYSSFKGGFGHVRL 971



 Score =  617 bits (1591), Expect(2) = 0.0
 Identities = 295/373 (79%), Positives = 331/373 (88%), Gaps = 1/373 (0%)
 Frame = +1

Query: 22   MANGMLEKKTEI-IIKPRTDKREYRRIVLPNALQVLLISDPETDKAAASMNVSVGYYSDP 198
            MA G  E+   + I+KPR DKR+YRRIVL N L++LLISDPETDK AASMNV VG +SDP
Sbjct: 1    MAVGKKEENMAVEIVKPRIDKRDYRRIVLQNNLEILLISDPETDKCAASMNVCVGAFSDP 60

Query: 199  EGLEGLAHFLEHMLFYASEKYPLEDSYSKYITEHGGSTNAFTSSEQTNYYFDINPNSFEE 378
            EGLEGLAHFLEHMLFYASEKYP+EDSYSKYITE+GGSTNAFTSSE TNYYF++N + FEE
Sbjct: 61   EGLEGLAHFLEHMLFYASEKYPVEDSYSKYITENGGSTNAFTSSEDTNYYFEVNADGFEE 120

Query: 379  ALDRFSQFFIKPLMSSDATTREIKAVDSENQKNLLSDGWRMSQLQKHLSAEAHPYHKFST 558
            ALDRF+QFFIKPLMS+DATTREIKAVDSE+QKNLLSD WRM+QLQKHLSAE HPYHKFST
Sbjct: 121  ALDRFAQFFIKPLMSADATTREIKAVDSEHQKNLLSDPWRMNQLQKHLSAENHPYHKFST 180

Query: 559  GNWDTLEVRPKEKGIDTRDRLIKFYEENYSANLMHLVVYGKESLNEMQSLVGCKFQDISN 738
            G+WDTLEVRPKE+GIDTR  L+KFY ENYSANLMHLVVY K+SL++++ LV  KFQDI N
Sbjct: 181  GSWDTLEVRPKERGIDTRQELLKFYSENYSANLMHLVVYSKDSLDKVEQLVRGKFQDIRN 240

Query: 739  ADRNCFHCPGQPCMPEHLQIIVKAVPVKQGHKLRVIWPITPSIRHYKESPCRYLGHLIGH 918
             DRN  H  GQPC+ EHLQI+V+AVP+KQGHKL++IWPITP I HYKE PCRYLGHLIGH
Sbjct: 241  IDRNQIHFTGQPCIMEHLQILVRAVPIKQGHKLKIIWPITPGIHHYKEGPCRYLGHLIGH 300

Query: 919  EGEGSLFYVLKKLGWATSLSAGEGDWTYEFSFFKVSIDLTDAGHDHMEDIVGLLFKYVLL 1098
            EGEGSLFYVLKKLGWATSLSAGE DWT EFSFFKV+IDLTDAG DH EDI+GLLFKY+ L
Sbjct: 301  EGEGSLFYVLKKLGWATSLSAGESDWTNEFSFFKVAIDLTDAGQDHFEDIMGLLFKYIHL 360

Query: 1099 LQQSGVKEWIFDE 1137
            LQQ+G  +WIF+E
Sbjct: 361  LQQAGASKWIFEE 373