BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Coptis23_contig00005039
         (2207 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002262830.2| PREDICTED: insulin-like growth factor-bindin...   743   0.0  
gb|AAK28636.1|AF360339_1 unknown protein [Arabidopsis thaliana]       730   0.0  
ref|NP_563980.2| leucine-rich repeat-containing protein [Arabido...   730   0.0  
ref|XP_002270172.1| PREDICTED: F-box/LRR-repeat protein 14 [Viti...   728   0.0  
ref|XP_002890123.1| leucine-rich repeat family protein [Arabidop...   726   0.0  

>ref|XP_002262830.2| PREDICTED: insulin-like growth factor-binding protein complex acid
            labile subunit-like [Vitis vinifera]
            gi|296084545|emb|CBI25566.3| unnamed protein product
            [Vitis vinifera]
          Length = 578

 Score =  743 bits (1919), Expect = 0.0
 Identities = 387/583 (66%), Positives = 449/583 (77%), Gaps = 1/583 (0%)
 Frame = +3

Query: 27   MGGACSRKRDQQEVNEEIIHTGSFRNYRKSSSTKWLRTSFQLGD-DVSQGRGKCPSLMEL 203
            MGG CSRKRDQQ V+E+ +       Y KS S+KWLRTSF     D   GR  CPSLMEL
Sbjct: 1    MGGVCSRKRDQQ-VDEDGVQIQVSGRYGKSGSSKWLRTSFSRPVIDCQLGRESCPSLMEL 59

Query: 204  CIHQIREDISKYINNYKTFSMLPRDISQQIFNELVYSHCLNDASLDAFRDCAIQDIYLGD 383
            CIH+I EDI +Y      FSMLPRDISQQIF+  V SHCL  ASL+AFRDCAIQD+ LG+
Sbjct: 60   CIHKICEDIDRYTK----FSMLPRDISQQIFDNFVDSHCLTSASLEAFRDCAIQDVNLGE 115

Query: 384  YHGVKDSWMDVICXXXXXXXXXXXXXXXXXXXXXXXXRDCKNLEATSFNYCDKISDIGLE 563
            Y  V DSWMD+I                         +DC N++  SFNYCD+IS+ GL+
Sbjct: 116  YPEVNDSWMDIISSQGLSLLSVDLSGSSVTDDGLSLLKDCSNIQVLSFNYCDQISEPGLK 175

Query: 564  HIRGLSNLTSLSFKKNNAITAQGMRALGNLSSLRNLDLERCSGIHGGLVHLKGLAKLESL 743
            +I GLSNLTSLSFKK+N +TA+GMRA  +L +L  LDLERCS IHGGL+HLKGL KLESL
Sbjct: 176  NISGLSNLTSLSFKKSNTVTAEGMRAFSSLVNLAKLDLERCSRIHGGLIHLKGLTKLESL 235

Query: 744  NIRCCNCITDVDMKPLSGLTNLKELQISCSKVSDLGVSYLKGLSKLVLLNMEGCPVTATC 923
            NIR C CITD D+K LSGLT+LKELQ+SCS ++D+G+SYLKGL KL+LL++EGC VT +C
Sbjct: 236  NIRYCKCITDSDLKALSGLTSLKELQMSCSNITDIGISYLKGLCKLMLLDVEGCHVTTSC 295

Query: 924  LESISALVSLSYLNLNRCNFSDQGCEKFIGLQKLRVLNLGFNNITDTCLVHIKGLTTLES 1103
            L+S+SALV+LSYLNLNRC  SD GCEKF GL+ L+VLN+GFNNITD CLVH+KGLT LES
Sbjct: 296  LDSLSALVALSYLNLNRCGLSDVGCEKFSGLKNLKVLNMGFNNITDACLVHLKGLTNLES 355

Query: 1104 LNLDSCGIGDEGMVHLAGLLRLKSLELSDTEVGSNGILHISCLTQLESLNLSFTVVTDSG 1283
            LNLDSC I DEG+ +L GL  LK LELSDT+VGSNG+ H+S LT+LESLNLSFT+VTDSG
Sbjct: 356  LNLDSCSIEDEGLANLTGLSLLKCLELSDTKVGSNGLCHLSGLTKLESLNLSFTLVTDSG 415

Query: 1284 LRKLTGLRSLKSLNLDARQIXXXXXXXXXXXXXXXXXXXFGARITDYGTNCLCYLKNLQS 1463
            L+KL GL SLKSLNLDARQI                   FGARI+D GTNCL + KNLQ+
Sbjct: 416  LKKLCGLTSLKSLNLDARQITDAGLAAITSLTGLTHLDLFGARISDAGTNCLRHFKNLQT 475

Query: 1464 LEICGGGLTDAGVKNIKNLASLTLLNLSQNGNLTDKTMELISGLTALVSLNISNSRVTDA 1643
            LEICGGGLTDAGVKNIK LASLTLLNLSQN NLTDKT+E+ISGLTALVSLN+SNSR+T+ 
Sbjct: 476  LEICGGGLTDAGVKNIKGLASLTLLNLSQNCNLTDKTLEMISGLTALVSLNVSNSRITNN 535

Query: 1644 GLQHIKSLRNLRSLSLEFCKVTATGIRKLQLTSLPKLVSFRPE 1772
            GLQH+K L+NL SLSLE CKVTA+ IRKLQ T+LP LVSFRPE
Sbjct: 536  GLQHLKPLKNLLSLSLESCKVTASEIRKLQSTALPNLVSFRPE 578


>gb|AAK28636.1|AF360339_1 unknown protein [Arabidopsis thaliana]
          Length = 585

 Score =  730 bits (1885), Expect = 0.0
 Identities = 380/584 (65%), Positives = 450/584 (77%), Gaps = 2/584 (0%)
 Frame = +3

Query: 27   MGGACSRKRDQQEVNEEIIHTGSFRNYRKSSSTKWLRTSF-QLGDDVSQGRGKCPSLMEL 203
            MGGACSRKRDQQ   E+I++ G    Y KSSS+KWL TS  + G DV +  G+CPSLMEL
Sbjct: 8    MGGACSRKRDQQV--EDILNRGVSGKYSKSSSSKWLATSLSRSGSDVKRKNGECPSLMEL 65

Query: 204  CIHQIREDISKYINNYKTFSMLPRDISQQIFNELVYSHCLNDASLDAFRDCAIQDIYLGD 383
            C+ +I+EDI +Y      FS LPRDISQQIF+ELVYS  L   SL+AFRDCAIQD+YLG+
Sbjct: 66   CVRKIQEDIDRYTK----FSDLPRDISQQIFDELVYSQRLTLKSLEAFRDCAIQDLYLGE 121

Query: 384  YHGVKDSWMDVICXXXXXXXXXXXXXXXXXXXXXXXXRDCKNLEATSFNYCDKISDIGLE 563
            Y GV D WMDVI                         + C NLE+ +FN+CD+IS+ GL 
Sbjct: 122  YPGVNDDWMDVISSQSTSLLSVDFSGSDITDSGLVSLKGCTNLESLNFNFCDQISNRGLV 181

Query: 564  HIRGLSNLTSLSFKKNNAITAQGMRALGNLSSLRNLDLERCSGIHGGLVHLKGLAKLESL 743
            H+ GLSNLTSLSF++N AITAQGMRAL NL +L+ LDLE+C GI GGLVHL+ L KLESL
Sbjct: 182  HLSGLSNLTSLSFRRNAAITAQGMRALSNLVNLKKLDLEKCPGIDGGLVHLRALTKLESL 241

Query: 744  NIRCCNCITDVDMKPLSGLTNLKELQISCSKVSDLGVSYLKGLSKLVLLNMEGCP-VTAT 920
            NI+ CNCITD DM+PLS LTNL+ LQI CSK++D+G+SYLKGL+KL LLN+EGC  VTA 
Sbjct: 242  NIKWCNCITDADMEPLSVLTNLRRLQICCSKITDIGISYLKGLNKLNLLNLEGCRHVTAA 301

Query: 921  CLESISALVSLSYLNLNRCNFSDQGCEKFIGLQKLRVLNLGFNNITDTCLVHIKGLTTLE 1100
            CL++++AL  L YLNLNRCNFSD GCEKF  L  L++LNLG NNIT++CLVH+KGLT LE
Sbjct: 302  CLDTLTALAGLMYLNLNRCNFSDSGCEKFSDLINLKILNLGMNNITNSCLVHLKGLTKLE 361

Query: 1101 SLNLDSCGIGDEGMVHLAGLLRLKSLELSDTEVGSNGILHISCLTQLESLNLSFTVVTDS 1280
            SLNLDSC IGDEG+VHL+G+L LKSLELSDTEVGSNG+ H+S L+ LES+NLSFTVVTDS
Sbjct: 362  SLNLDSCRIGDEGLVHLSGMLELKSLELSDTEVGSNGLRHLSGLSNLESINLSFTVVTDS 421

Query: 1281 GLRKLTGLRSLKSLNLDARQIXXXXXXXXXXXXXXXXXXXFGARITDYGTNCLCYLKNLQ 1460
            GLRKL+GL SL++LNLDAR +                   FGARITD GTN L  LK LQ
Sbjct: 422  GLRKLSGLTSLRTLNLDARHVTDAGLSALTSLTGLTHLDLFGARITDSGTNHLRNLKKLQ 481

Query: 1461 SLEICGGGLTDAGVKNIKNLASLTLLNLSQNGNLTDKTMELISGLTALVSLNISNSRVTD 1640
            SLEICGGGLTD GVKNIK+L+SLTLLNLSQN NLTDKT+ELISGLT LVSLN+SNSRV+ 
Sbjct: 482  SLEICGGGLTDTGVKNIKDLSSLTLLNLSQNSNLTDKTLELISGLTGLVSLNVSNSRVSS 541

Query: 1641 AGLQHIKSLRNLRSLSLEFCKVTATGIRKLQLTSLPKLVSFRPE 1772
            +GL+H+K L+NLRSL+LE CK++A  IRKLQ T LP LV+FRPE
Sbjct: 542  SGLRHLKPLKNLRSLTLESCKLSANDIRKLQATDLPNLVNFRPE 585


>ref|NP_563980.2| leucine-rich repeat-containing protein [Arabidopsis thaliana]
            gi|23297087|gb|AAN13089.1| unknown protein [Arabidopsis
            thaliana] gi|332191234|gb|AEE29355.1| leucine-rich
            repeat-containing protein [Arabidopsis thaliana]
          Length = 585

 Score =  730 bits (1885), Expect = 0.0
 Identities = 380/584 (65%), Positives = 450/584 (77%), Gaps = 2/584 (0%)
 Frame = +3

Query: 27   MGGACSRKRDQQEVNEEIIHTGSFRNYRKSSSTKWLRTSF-QLGDDVSQGRGKCPSLMEL 203
            MGGACSRKRDQQ   E+I++ G    Y KSSS+KWL TS  + G DV +  G+CPSLMEL
Sbjct: 8    MGGACSRKRDQQV--EDILNRGVSGKYSKSSSSKWLATSLSRSGSDVKRKNGECPSLMEL 65

Query: 204  CIHQIREDISKYINNYKTFSMLPRDISQQIFNELVYSHCLNDASLDAFRDCAIQDIYLGD 383
            C+ +I+EDI +Y      FS LPRDISQQIF+ELVYS  L   SL+AFRDCAIQD+YLG+
Sbjct: 66   CVRKIQEDIDRYTK----FSDLPRDISQQIFDELVYSQRLTLKSLEAFRDCAIQDLYLGE 121

Query: 384  YHGVKDSWMDVICXXXXXXXXXXXXXXXXXXXXXXXXRDCKNLEATSFNYCDKISDIGLE 563
            Y GV D WMDVI                         + C NLE+ +FN+CD+IS+ GL 
Sbjct: 122  YPGVNDDWMDVISSQSTSLLSVDFSGSDITDSGLVSLKGCTNLESLNFNFCDQISNRGLV 181

Query: 564  HIRGLSNLTSLSFKKNNAITAQGMRALGNLSSLRNLDLERCSGIHGGLVHLKGLAKLESL 743
            H+ GLSNLTSLSF++N AITAQGMRAL NL +L+ LDLE+C GI GGLVHL+ L KLESL
Sbjct: 182  HLSGLSNLTSLSFRRNAAITAQGMRALSNLVNLKKLDLEKCPGIDGGLVHLRALTKLESL 241

Query: 744  NIRCCNCITDVDMKPLSGLTNLKELQISCSKVSDLGVSYLKGLSKLVLLNMEGCP-VTAT 920
            NI+ CNCITD DM+PLS LTNL+ LQI CSK++D+G+SYLKGL+KL LLN+EGC  VTA 
Sbjct: 242  NIKWCNCITDADMEPLSVLTNLRSLQICCSKITDIGISYLKGLNKLNLLNLEGCRHVTAA 301

Query: 921  CLESISALVSLSYLNLNRCNFSDQGCEKFIGLQKLRVLNLGFNNITDTCLVHIKGLTTLE 1100
            CL++++AL  L YLNLNRCNFSD GCEKF  L  L++LNLG NNIT++CLVH+KGLT LE
Sbjct: 302  CLDTLTALAGLMYLNLNRCNFSDSGCEKFSDLINLKILNLGMNNITNSCLVHLKGLTKLE 361

Query: 1101 SLNLDSCGIGDEGMVHLAGLLRLKSLELSDTEVGSNGILHISCLTQLESLNLSFTVVTDS 1280
            SLNLDSC IGDEG+VHL+G+L LKSLELSDTEVGSNG+ H+S L+ LES+NLSFTVVTDS
Sbjct: 362  SLNLDSCRIGDEGLVHLSGMLELKSLELSDTEVGSNGLRHLSGLSNLESINLSFTVVTDS 421

Query: 1281 GLRKLTGLRSLKSLNLDARQIXXXXXXXXXXXXXXXXXXXFGARITDYGTNCLCYLKNLQ 1460
            GLRKL+GL SL++LNLDAR +                   FGARITD GTN L  LK LQ
Sbjct: 422  GLRKLSGLTSLRTLNLDARHVTDAGLSALTSLTGLTHLDLFGARITDSGTNHLRNLKKLQ 481

Query: 1461 SLEICGGGLTDAGVKNIKNLASLTLLNLSQNGNLTDKTMELISGLTALVSLNISNSRVTD 1640
            SLEICGGGLTD GVKNIK+L+SLTLLNLSQN NLTDKT+ELISGLT LVSLN+SNSRV+ 
Sbjct: 482  SLEICGGGLTDTGVKNIKDLSSLTLLNLSQNSNLTDKTLELISGLTGLVSLNVSNSRVSS 541

Query: 1641 AGLQHIKSLRNLRSLSLEFCKVTATGIRKLQLTSLPKLVSFRPE 1772
            +GL+H+K L+NLRSL+LE CK++A  IRKLQ T LP LV+FRPE
Sbjct: 542  SGLRHLKPLKNLRSLTLESCKLSANDIRKLQATDLPNLVNFRPE 585


>ref|XP_002270172.1| PREDICTED: F-box/LRR-repeat protein 14 [Vitis vinifera]
            gi|297743556|emb|CBI36423.3| unnamed protein product
            [Vitis vinifera]
          Length = 578

 Score =  728 bits (1880), Expect = 0.0
 Identities = 385/583 (66%), Positives = 439/583 (75%), Gaps = 1/583 (0%)
 Frame = +3

Query: 27   MGGACSRKRDQQEVNEEIIHTGSFRNYRKSSSTKWLRTSFQLGD-DVSQGRGKCPSLMEL 203
            MGGACSRKRD Q VNE+ +  G    Y +  S+KWL TS      D+ QGRG+CPSLMEL
Sbjct: 1    MGGACSRKRDPQ-VNEDSLQRGVSGKYCRIGSSKWLGTSISRPALDILQGRGQCPSLMEL 59

Query: 204  CIHQIREDISKYINNYKTFSMLPRDISQQIFNELVYSHCLNDASLDAFRDCAIQDIYLGD 383
            CI++IREDI KY     TFSMLPRDISQQIFNELV+S CL D SL AF+DCA+QDIYLG+
Sbjct: 60   CIYKIREDIDKYT----TFSMLPRDISQQIFNELVFSQCLTDVSLKAFQDCALQDIYLGE 115

Query: 384  YHGVKDSWMDVICXXXXXXXXXXXXXXXXXXXXXXXXRDCKNLEATSFNYCDKISDIGLE 563
            Y GV DSWMDVI                         +DC NL+A + NYCD+ISD GL+
Sbjct: 116  YPGVSDSWMDVISSQGVSLLSVDLSGSEITNSGLIHLKDCTNLQALNLNYCDQISDHGLK 175

Query: 564  HIRGLSNLTSLSFKKNNAITAQGMRALGNLSSLRNLDLERCSGIHGGLVHLKGLAKLESL 743
            HI GLSNLT+LSF++NNAITAQGM A  +L +L  LDLERC GIHGGL+HLKGL KLESL
Sbjct: 176  HISGLSNLTTLSFRRNNAITAQGMSAFSSLVNLVKLDLERCPGIHGGLIHLKGLTKLESL 235

Query: 744  NIRCCNCITDVDMKPLSGLTNLKELQISCSKVSDLGVSYLKGLSKLVLLNMEGCPVTATC 923
            NI  C+CITD D+KPLSGLTNLK L+IS SKV+D GV+YLKGL KL LLNMEGCPVTA C
Sbjct: 236  NINMCHCITDADLKPLSGLTNLKGLEISRSKVTDDGVAYLKGLHKLALLNMEGCPVTAAC 295

Query: 924  LESISALVSLSYLNLNRCNFSDQGCEKFIGLQKLRVLNLGFNNITDTCLVHIKGLTTLES 1103
            LES+S L SL  LNLNR   SD GCE F   + LRVLNLGFN++TD CLVH+KGLT LES
Sbjct: 296  LESLSDLPSLLSLNLNRSMLSDDGCENFARQENLRVLNLGFNDLTDACLVHLKGLTNLES 355

Query: 1104 LNLDSCGIGDEGMVHLAGLLRLKSLELSDTEVGSNGILHISCLTQLESLNLSFTVVTDSG 1283
            LNLDSC I DEG+ +L GL  LK LELSDTEVGSNG+ H+S L  LES+NLSFT VTDSG
Sbjct: 356  LNLDSCRICDEGLANLTGLRHLKCLELSDTEVGSNGLRHLSGLANLESINLSFTAVTDSG 415

Query: 1284 LRKLTGLRSLKSLNLDARQIXXXXXXXXXXXXXXXXXXXFGARITDYGTNCLCYLKNLQS 1463
            LRKL+ L SLKSLNLDARQI                   FGARITD GT+ L   KNLQS
Sbjct: 416  LRKLSALSSLKSLNLDARQITDAGLAALTSLTGLTHLDLFGARITDSGTSYLRNFKNLQS 475

Query: 1464 LEICGGGLTDAGVKNIKNLASLTLLNLSQNGNLTDKTMELISGLTALVSLNISNSRVTDA 1643
            LEICGGGLTDAGVKNIK+L  LT+LNLSQN NLTDK++ELISGLTALVSL++SNSR+T+A
Sbjct: 476  LEICGGGLTDAGVKNIKDLTCLTVLNLSQNCNLTDKSLELISGLTALVSLSVSNSRITNA 535

Query: 1644 GLQHIKSLRNLRSLSLEFCKVTATGIRKLQLTSLPKLVSFRPE 1772
            GLQH+K L+NL+SL+L+ CKVT   I+KLQ   LP LVSFRPE
Sbjct: 536  GLQHLKQLKNLKSLTLDSCKVTVNDIKKLQSKDLPNLVSFRPE 578


>ref|XP_002890123.1| leucine-rich repeat family protein [Arabidopsis lyrata subsp. lyrata]
            gi|297335965|gb|EFH66382.1| leucine-rich repeat family
            protein [Arabidopsis lyrata subsp. lyrata]
          Length = 578

 Score =  726 bits (1874), Expect = 0.0
 Identities = 377/584 (64%), Positives = 451/584 (77%), Gaps = 2/584 (0%)
 Frame = +3

Query: 27   MGGACSRKRDQQEVNEEIIHTGSFRNYRKSSSTKWLRTSF-QLGDDVSQGRGKCPSLMEL 203
            MGGACSRKRDQQ   E+I++ G    Y KSSS+KWL TS  + G DV +  G+CPSLMEL
Sbjct: 1    MGGACSRKRDQQV--EDILNRGVSGKYSKSSSSKWLATSLSRSGSDVKRKNGECPSLMEL 58

Query: 204  CIHQIREDISKYINNYKTFSMLPRDISQQIFNELVYSHCLNDASLDAFRDCAIQDIYLGD 383
            CI +I+E I +Y      FS LPRDISQQIF+ELVYS  L   SL+AFRDCAIQD+ LG+
Sbjct: 59   CIRKIQEVIDRYTK----FSDLPRDISQQIFDELVYSQRLTLKSLEAFRDCAIQDLCLGE 114

Query: 384  YHGVKDSWMDVICXXXXXXXXXXXXXXXXXXXXXXXXRDCKNLEATSFNYCDKISDIGLE 563
            Y GV D WMDVI                         + C NLE+ +FN+CD+IS+ GLE
Sbjct: 115  YPGVNDDWMDVISSQSTSLLSVDFSGSDITDSGLVSLKGCTNLESLNFNFCDQISNRGLE 174

Query: 564  HIRGLSNLTSLSFKKNNAITAQGMRALGNLSSLRNLDLERCSGIHGGLVHLKGLAKLESL 743
            H+ GLSNLTSLSF++N AITAQGMRAL NL +++ LDLE+C GIHGGLVHL+GL KLESL
Sbjct: 175  HLSGLSNLTSLSFRRNAAITAQGMRALSNLVNMKKLDLEKCPGIHGGLVHLRGLTKLESL 234

Query: 744  NIRCCNCITDVDMKPLSGLTNLKELQISCSKVSDLGVSYLKGLSKLVLLNMEGCP-VTAT 920
            NI+ CNCITD DM+PLS LTNL+ LQI CS+++D+G+SYLKGL+KL LLN+EGC  VTA 
Sbjct: 235  NIKWCNCITDADMEPLSELTNLRSLQICCSRITDIGISYLKGLNKLNLLNLEGCRHVTAA 294

Query: 921  CLESISALVSLSYLNLNRCNFSDQGCEKFIGLQKLRVLNLGFNNITDTCLVHIKGLTTLE 1100
            CL++++AL  L +LNLNRCNFSD GCEKF  L  L++LNLG N+IT++CLVH++GLT LE
Sbjct: 295  CLDTLTALTGLMFLNLNRCNFSDSGCEKFSDLINLKILNLGMNSITNSCLVHLRGLTKLE 354

Query: 1101 SLNLDSCGIGDEGMVHLAGLLRLKSLELSDTEVGSNGILHISCLTQLESLNLSFTVVTDS 1280
            SLNLDSC IGDEG+VHL+G+L LKSLELSDTEVGSNG+ H+S L+ LES+NLSFTVVTDS
Sbjct: 355  SLNLDSCRIGDEGLVHLSGMLELKSLELSDTEVGSNGLRHLSGLSNLESINLSFTVVTDS 414

Query: 1281 GLRKLTGLRSLKSLNLDARQIXXXXXXXXXXXXXXXXXXXFGARITDYGTNCLCYLKNLQ 1460
            GLRKL+GL SL++LNLDAR +                   FGARITD GTN L  LK LQ
Sbjct: 415  GLRKLSGLTSLRTLNLDARHVTDAGLSALTSLTGLTHLDLFGARITDSGTNHLRNLKKLQ 474

Query: 1461 SLEICGGGLTDAGVKNIKNLASLTLLNLSQNGNLTDKTMELISGLTALVSLNISNSRVTD 1640
            SLEICGGGLTD GVKNIK+L+SLTLLNLSQN NLTDKT+ELISGLT LVSLN+SNSRV+ 
Sbjct: 475  SLEICGGGLTDTGVKNIKDLSSLTLLNLSQNSNLTDKTLELISGLTGLVSLNVSNSRVSS 534

Query: 1641 AGLQHIKSLRNLRSLSLEFCKVTATGIRKLQLTSLPKLVSFRPE 1772
            +GL+H+K L+NLRSL+LE CK++A  IRKLQ T LP LV+FRPE
Sbjct: 535  SGLRHLKPLKNLRSLTLESCKLSANDIRKLQATDLPNLVNFRPE 578