BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Coptis23_contig00001757
         (2226 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002276470.2| PREDICTED: uncharacterized protein At5g41620...   647   0.0  
ref|XP_002509896.1| conserved hypothetical protein [Ricinus comm...   567   e-159
ref|XP_002276152.2| PREDICTED: uncharacterized protein At5g41620...   510   e-142
ref|XP_002299501.1| predicted protein [Populus trichocarpa] gi|2...   503   e-139
ref|XP_002303618.1| predicted protein [Populus trichocarpa] gi|2...   501   e-139

>ref|XP_002276470.2| PREDICTED: uncharacterized protein At5g41620-like [Vitis vinifera]
          Length = 648

 Score =  647 bits (1668), Expect = 0.0
 Identities = 370/657 (56%), Positives = 450/657 (68%), Gaps = 38/657 (5%)
 Frame = -2

Query: 2060 KLKRGVLVGKRRGPTTPSPTWKLFSPSSDQENNLNTSLTLPXXXXXARKLCANLWEVHHQ 1881
            KLKRGVLVGKR GP TPSPTW+L    +D  ++++  L         RKL ANLWE+  Q
Sbjct: 4    KLKRGVLVGKRGGPCTPSPTWRLGFSLNDATSSIDKDLDCSTSVSA-RKLGANLWEI--Q 60

Query: 1880 HHLPVTKMSKGGGLSRIRHYREKGLHLPTHLADPSHTPLHQVA----------------- 1752
             HLPV  M++GGG  R  H+++KG  LPTHL DP H+P  Q                   
Sbjct: 61   SHLPVANMNRGGGRLRHHHHKDKGFELPTHLVDPPHSPPDQPESASSLRRHVAASLMQHH 120

Query: 1751 --------AYYPPS------TPASSLDSKGRPGESSHSLKTSTEFLKVLNRIWSLEEQHA 1614
                    A  P S      TP SSLD KGR GESS++LKTSTE LKVLNRIWSLEEQHA
Sbjct: 121  RSVERNGRALQPVSPASYSITPTSSLDFKGRIGESSYNLKTSTELLKVLNRIWSLEEQHA 180

Query: 1613 SNVSLVKALKIDLHSARTRIKELLQEQQADRNEIDDLMKQIAEDKLFRKSKETDRIKSTL 1434
            S +SLVKALK++L  +R RIKELLQE+Q +R E+DDLMKQ+AEDKL RK+KE DRIK+ +
Sbjct: 181  STISLVKALKMELDHSRARIKELLQEKQTERQEMDDLMKQVAEDKLIRKTKEQDRIKAAV 240

Query: 1433 QSVRDELEDERKLRKRSESLHRKLARELSETKSAFSRALKELERERKARTLLEDLCDEFA 1254
            QSVRDELEDERKLRKRSE+LHRKLARELSE KS+FS AL+ELERE+KAR LLEDLCDEFA
Sbjct: 241  QSVRDELEDERKLRKRSETLHRKLARELSEVKSSFSNALRELEREKKARILLEDLCDEFA 300

Query: 1253 TGIGDYEQEVRALRHKNEKDQGGKDDQDRLIVHISEAWLDERLQMKLAEAQCDVSEKNTI 1074
             GI +YEQEVR+L+HK EKD+  +++ DRL++HISEAWLDER+QMKLAEA+CDV+EKNTI
Sbjct: 301  KGIREYEQEVRSLKHKPEKDRVARENSDRLVLHISEAWLDERMQMKLAEARCDVAEKNTI 360

Query: 1073 VDKLSFEIETFLKAKRSGNLNRNEISPSRDSKKHKNLRRHSLESVHFLGATSAPQDVGDE 894
            VDKLSFEIETFL+AK+S    R++ S S   +K   LRRHSLES H   A SAPQ+  DE
Sbjct: 361  VDKLSFEIETFLRAKQSVTSRRDDYS-SPSEQKESRLRRHSLESFHLNEAVSAPQNAEDE 419

Query: 893  EDSVGSDSHCFELVNKNMGDKATGSISKPKLHELGEEAVEDDELGETRKPNYVKKKPGTG 714
            EDS  SDSHCFEL NK  G K +    K  +    E   ED     T K    KKK G+ 
Sbjct: 420  EDSSDSDSHCFEL-NKGSGAKQSNGSCKKHIGNSAEGHAED-----TVKSYPTKKKSGSQ 473

Query: 713  ERTKARNPSGSKTQFEEQIKRAMSSNENKSQFLNREDKKGGEEADPVEISISQKSENCEA 534
            E TK R PSG +TQFEE + R MS N NK+Q ++ E  + G + D VEI+ SQK E  EA
Sbjct: 474  EITKGRKPSGLRTQFEEYMARTMSCNGNKTQLVDSEQGEMGGD-DSVEINNSQKFEPNEA 532

Query: 533  TN----EKKLRNDGIHGSHSNNVIEGLLRRSRMLLADGGRKEIHSEDDGVEDSG---AWR 375
            T     EKK +  G  G + N+V++ L+R     L     +++H E++  ED+G      
Sbjct: 533  TQESMPEKKNKRAGARGVNLNHVLDNLIRNHSSPLEG---EKVHPENNCREDAGNQSVLM 589

Query: 374  GIASPVQQWVSRFAAPDLEISESSSQWAPSLKGNTLKARLMEARLEGQHSRLKASKG 204
            G ASP+QQW+S+  +PDLEISESSS+W    + N+LKA+L+EARLEGQH R KASKG
Sbjct: 590  GHASPIQQWMSKLTSPDLEISESSSKWPRGSRENSLKAKLLEARLEGQHFRAKASKG 646


>ref|XP_002509896.1| conserved hypothetical protein [Ricinus communis]
            gi|223549795|gb|EEF51283.1| conserved hypothetical
            protein [Ricinus communis]
          Length = 696

 Score =  567 bits (1461), Expect = e-159
 Identities = 352/719 (48%), Positives = 451/719 (62%), Gaps = 83/719 (11%)
 Frame = -2

Query: 2111 EGKGRNQGAEKQENLTIKLKRGVLVGKRRGP--TTPSPTWKLFSPSS----------DQE 1968
            +GK     AEK++NL  KLKR VLVGK+ GP   TP   W+  +P +          DQE
Sbjct: 2    KGKSGKGAAEKEDNLGEKLKRWVLVGKKVGPFSCTPVRFWRSVAPPTAHFSIIAKHQDQE 61

Query: 1967 --------NNLNTSLTLPXXXXXARKLCANLWEVHHQHHLPVTKMSKG-----GGLS--- 1836
                    NN   +  +       RKL A LWE   QH+LP++KM +G      G +   
Sbjct: 62   EPPFVSYSNNKKAATVVSA-----RKLAAALWEF--QHYLPLSKMHRGMHNHSNGTACDP 114

Query: 1835 RIRH--------YREKGLHLPTHLADPSHTPLHQ-------------------------- 1758
            R+R         +++KGL L   LADPS +   Q                          
Sbjct: 115  RLRRHQNRHHHLFKDKGLDLSHFLADPSASSTDQPESAGSLRRHIAASLIQHHRSIEKSN 174

Query: 1757 ----------------VAAYYPPSTPASSLDSKGRPGESSHSLKTSTEFLKVLNRIWSLE 1626
                            VA Y P  TP+SSLD KGR GES +SLKTSTE LKVLNRIWSLE
Sbjct: 175  HALQPVSPASYGSSMEVAPYNPAVTPSSSLDFKGRIGESHYSLKTSTELLKVLNRIWSLE 234

Query: 1625 EQHASNVSLVKALKIDLHSARTRIKELLQEQQADRNEIDDLMKQIAEDKLFRKSKETDRI 1446
            EQH+SN+SL+KALK++L  AR RIKELL++QQADR+EIDDLMKQIAEDKL RKSKE DR+
Sbjct: 235  EQHSSNMSLIKALKMELDHARVRIKELLRDQQADRHEIDDLMKQIAEDKLVRKSKEQDRL 294

Query: 1445 KSTLQSVRDELEDERKLRKRSESLHRKLARELSETKSAFSRALKELERERKARTLLEDLC 1266
             + +QS+RDE+EDERKLRKRSESLHRKLARELSE KS+ S A+KE+E+ERK+R LLEDLC
Sbjct: 295  HAAIQSLRDEIEDERKLRKRSESLHRKLARELSEVKSSLSNAVKEMEKERKSRKLLEDLC 354

Query: 1265 DEFATGIGDYEQEVRALRHKNEKDQGGKDDQDRLIVHISEAWLDERLQMKLAEAQCDVSE 1086
            DEFA GI DYEQE+ A++ K++KD  GK D DRLI+HISE+WLDER+QM+L EAQ   +E
Sbjct: 355  DEFARGIKDYEQELHAVKPKSDKDWVGKADGDRLILHISESWLDERMQMRLEEAQHGFAE 414

Query: 1085 KNTIVDKLSFEIETFLKAKRSGNLNRNEISPSRDSKKHKNLRRHSLESVHFLGATSAPQD 906
             N+IVDKL FE+ETFLKAKR  N      S      K    RR+S+ESV    A SAPQD
Sbjct: 415  NNSIVDKLGFELETFLKAKRVAN------SMINTDNKLPRERRNSMESVPLNEAVSAPQD 468

Query: 905  VGDEEDSVGSDSHCFELVNKNMGDKATGSISKPKLHELGEEAVEDDELGETRKPNYVKKK 726
            VGDEEDS+ SDSHCFEL   + G+          LH  G+EA+ DD + ET K +  KKK
Sbjct: 469  VGDEEDSISSDSHCFELNKPSNGEF--------NLH--GDEAL-DDHVDETVKSSQTKKK 517

Query: 725  PGTGERTKARNPSGSKTQFEEQIKRAMSSN-ENKSQFLNREDKKGGEEADPVEISISQKS 549
              + ER + +NPS  + +FEEQ+  AM++N  NK   +  E+ K G E +P E+SIS++S
Sbjct: 518  SASHERNRRQNPSSLQVKFEEQMAWAMAANGNNKFPVVGIEELKTG-EGNPAEMSISRRS 576

Query: 548  ENCEATN----EKKLRNDGIHGSHSNNVIEGLLRRSRMLLADGGRKEIHSEDDGVEDSGA 381
            ENC+ T     E+K + D IHG + N VI+ L+ RS +  ++ G   + ++      S  
Sbjct: 577  ENCDTTEGGSIERKKKVDEIHGMNQNYVIDNLI-RSHISSSEAGHVRLENDAGEASTSYP 635

Query: 380  WRGIASPVQQWVSRFAAPDLEISESSSQWAPSLKGNTLKARLMEARLEGQHSRLKASKG 204
             R  ASPV+QW+++ + PDL+ISESS++   +LK NTLKA+L+EAR +GQ SRLK  +G
Sbjct: 636  TRRNASPVRQWMAKLSTPDLDISESSTKQPSTLKENTLKAKLLEARSKGQRSRLKIFRG 694


>ref|XP_002276152.2| PREDICTED: uncharacterized protein At5g41620-like [Vitis vinifera]
          Length = 602

 Score =  510 bits (1314), Expect = e-142
 Identities = 310/613 (50%), Positives = 386/613 (62%), Gaps = 51/613 (8%)
 Frame = -2

Query: 1895 EVHHQHHLPVTKMSKGGGLSRIRHYREKGLHLPTHLADPSHTPLHQVAA----------- 1749
            ++ H+HHL               HYR+KGL LPT L DP  T   Q A+           
Sbjct: 17   KLRHRHHL---------------HYRDKGLDLPTLLTDPFPTSPDQPASASSLRRHVATT 61

Query: 1748 -------------------------------YYPPSTPASSLDSKGRPGESSHSLKTSTE 1662
                                           Y P  TP SSLD KG  GESS+SLKTST+
Sbjct: 62   LMQHRRANERNSRALQPVSPASYGSSLEVGPYNPAVTPTSSLDFKGGIGESSYSLKTSTD 121

Query: 1661 FLKVLNRIWSLEEQHASNVSLVKALKIDLHSARTRIKELLQEQQADRNEIDDLMKQIAED 1482
             LKVLNRIWSLEEQHASNVSL+KALK++L  AR RIK LL++QQA+R+EIDDLMKQ+ ED
Sbjct: 122  LLKVLNRIWSLEEQHASNVSLIKALKMELGHARARIKRLLRDQQAERHEIDDLMKQV-ED 180

Query: 1481 KLFRK-SKETDRIKSTLQSVRDELEDERKLRKRSESLHRKLARELSETKSAFSRALKELE 1305
            KL RK SKE DR+ S +QSVRDELE+ERKLRK SESLHRKLARELSE KS+FS ALKELE
Sbjct: 181  KLLRKSSKEQDRVNSAVQSVRDELENERKLRKHSESLHRKLARELSEVKSSFSNALKELE 240

Query: 1304 RERKARTLLEDLCDEFATGIGDYEQEVRALRHKNEKDQGGKDDQDRLIVHISEAWLDERL 1125
            +ERK+R LLEDLCDEFA GI DY+QEV AL+ K++ D  G+ D DRLI+H+SE+WLDER+
Sbjct: 241  KERKSRELLEDLCDEFAKGIRDYQQEVHALKQKSDSDWAGRADHDRLILHLSESWLDERM 300

Query: 1124 QMKLAEAQCDVSEKNTIVDKLSFEIETFLKAKRSGNLNRNEISPSRDSKKHKNLRRHSLE 945
            Q KL E Q   +E N I+DKLSFEIETFL+AK+      N     R+  K + LRR+SLE
Sbjct: 301  QTKLVETQLGSAENNPILDKLSFEIETFLQAKQMHTSKTNSNMLPREPTKERYLRRNSLE 360

Query: 944  SVHFLGATSAPQDVGDEEDSVGSDSHCFELVNKNMGDKATGSISKPKLHELGEEAVEDDE 765
            SV    A SAPQD GDEE S GSD++CFEL      +K T S  KP           D+ 
Sbjct: 361  SVPLHDAVSAPQDAGDEEASAGSDTNCFEL------NKPTTSNFKPH---------GDEP 405

Query: 764  LGETRKPNYVKKKPGTGERTKARNPSGSKTQFEEQIKRAMSSNENK-SQFLNREDKKGGE 588
               T +    KKK    ER K RNPS  + +FEEQ+ RAM+ N NK +Q ++ + ++   
Sbjct: 406  EAHTDRMIKSKKKLVPHERIKGRNPSSLQVKFEEQMARAMACNGNKTTQVVDTDQQRKIS 465

Query: 587  EADPVEISISQKSENCEATN----EKKLRNDGIHGSHSNNVIEGLLRRSRMLLADGGRKE 420
            E  P+E SI+ K ENCEAT     E+K+++D I    + N     L RS+ L ++ G   
Sbjct: 466  EGIPLEASITPKPENCEATEDRSYERKIKHDAIIQEPNLNYDIDSLIRSQYLSSEAGNIR 525

Query: 419  IHSEDDGVEDS---GAWRGIASPVQQWVSRFAAPDLEISESSSQWAPSLKGNTLKARLME 249
              ++DD  E S    AWR   SPV++W+ +  +PDL+I ESSS+ AP  K NTLKA+L+E
Sbjct: 526  PENDDDCCEASFGNSAWRSHGSPVREWMVKLTSPDLDIPESSSKLAP--KENTLKAKLLE 583

Query: 248  ARLEGQHSRLKAS 210
            ARL+G+ SRLKA+
Sbjct: 584  ARLKGKRSRLKAT 596


>ref|XP_002299501.1| predicted protein [Populus trichocarpa] gi|222846759|gb|EEE84306.1|
            predicted protein [Populus trichocarpa]
          Length = 576

 Score =  503 bits (1294), Expect = e-139
 Identities = 297/551 (53%), Positives = 368/551 (66%), Gaps = 6/551 (1%)
 Frame = -2

Query: 1838 SRIRHYR--EKGLHLPTHLADPSHTPLHQVAAYYPPSTPASSLDSKGRPGESSHSLKTST 1665
            S I+H+R  E+  H    ++  S+    +VA Y P  TP+SSLD KGR GES +SLKTST
Sbjct: 64   SLIQHHRSIERSNHALQPVSPASYGSSMEVAPYNPAVTPSSSLDFKGRIGESHYSLKTST 123

Query: 1664 EFLKVLNRIWSLEEQHASNVSLVKALKIDLHSARTRIKELLQEQQADRNEIDDLMKQIAE 1485
            E LKVLNRIWSLEEQH SNVSL+KALKI+L  AR RIKELL+ QQADR+EIDDLMKQIAE
Sbjct: 124  ELLKVLNRIWSLEEQHVSNVSLIKALKIELDHARIRIKELLRYQQADRHEIDDLMKQIAE 183

Query: 1484 DKLFRKSKETDRIKSTLQSVRDELEDERKLRKRSESLHRKLARELSETKSAFSRALKELE 1305
            DKL +KSKE +R+ + +QS+RDELEDERKLRKRSESLHRKLARELSE KS+FS ALKE+E
Sbjct: 184  DKLVQKSKEQERLHAAIQSLRDELEDERKLRKRSESLHRKLARELSEVKSSFSNALKEME 243

Query: 1304 RERKARTLLEDLCDEFATGIGDYEQEVRALRHKNEKDQGGKDDQDRLIVHISEAWLDERL 1125
            RERK+R LLEDLCDEFA GI DYEQEV  L  K+++D   + D DRLI+HISE+WLDER+
Sbjct: 244  RERKSRKLLEDLCDEFAKGIKDYEQEVHTLNKKSDRDWVRRADGDRLILHISESWLDERM 303

Query: 1124 QMKLAEAQCDVSEKNTIVDKLSFEIETFLKAKRSGN-LNRNEISPSRDSKKHKNLRRHSL 948
            QM+L EAQ   SE N+IVDKL FEIETFLK KR GN  + N + P          RR+S+
Sbjct: 304  QMRLEEAQHGFSENNSIVDKLGFEIETFLKTKRMGNSKSSNNVLPRE--------RRNSM 355

Query: 947  ESVHFLGATSAPQDVGDEEDSVGSDSHCFELVNKNMGDKATGSISKPKLHELGEEAVEDD 768
            ESV      SAPQDVGDE+DS GSDSHCF+       D           H  G+EAV   
Sbjct: 356  ESVPLNETVSAPQDVGDEQDSTGSDSHCFKHNRPGNDD----------FHLHGDEAVA-G 404

Query: 767  ELGETRKPNYVKKKPGTGERTKARNPSGSKTQFEEQIKRAMSSNEN-KSQFLNREDKKGG 591
               E  K    KKK  + ER++ +NPS  + +FEE   +AM  N N KS+ +  E  K G
Sbjct: 405  HTDEMEKSTRTKKKLASRERSRCQNPSNLQVKFEEHKAQAMPCNGNKKSEVMELEGVKTG 464

Query: 590  EEADPVEISISQKSENCEATNEKKLRNDGIHGSHSNNVIEGLLRRSRMLLADGGRKEIHS 411
                               + E+K + D IHGS+SN VI+ L+R     ++      +H 
Sbjct: 465  ------------------GSLERKSKVDEIHGSNSNYVIDNLIRSH---ISSSEAVNLHL 503

Query: 410  EDDGVEDSGAW--RGIASPVQQWVSRFAAPDLEISESSSQWAPSLKGNTLKARLMEARLE 237
            E+D  E S ++  R  ASPV+QW+S+  +PDL+ISESS++  P+LK NTLKA+L+EAR +
Sbjct: 504  ENDAGEASCSYPPRRYASPVRQWMSKLTSPDLDISESSTKPPPNLKENTLKAKLLEARSK 563

Query: 236  GQHSRLKASKG 204
            G  SRL+  KG
Sbjct: 564  GPRSRLRIFKG 574


>ref|XP_002303618.1| predicted protein [Populus trichocarpa] gi|222841050|gb|EEE78597.1|
            predicted protein [Populus trichocarpa]
          Length = 593

 Score =  501 bits (1290), Expect = e-139
 Identities = 311/631 (49%), Positives = 390/631 (61%), Gaps = 59/631 (9%)
 Frame = -2

Query: 1919 RKLCANLWEVHHQHHLP-VTKMSKG------GGLSRIRHY-------REKGLHLPTHLAD 1782
            RKL A LWE +H  +LP ++KM +G      GG SR+R +       ++KGL L   LAD
Sbjct: 8    RKLAAALWEFNH--YLPSLSKMHRGVHINNGGGDSRLRRHEKRHHFLKDKGLDLSHFLAD 65

Query: 1781 PSHTPLHQ------------------------------------------VAAYYPPSTP 1728
            P+ T   Q                                          VA Y P  TP
Sbjct: 66   PTPTSPDQPESAGSLRRHIASSLIQHHRSIERSNRALQPVSPASYGSSMEVAPYNPAVTP 125

Query: 1727 ASSLDSKGRPGESSHSLKTSTEFLKVLNRIWSLEEQHASNVSLVKALKIDLHSARTRIKE 1548
            +SSLD KGR GES +SLKTSTE LKVLNRIWSLEEQHASN+SL+KALK +L  AR RIKE
Sbjct: 126  SSSLDFKGRIGESHYSLKTSTELLKVLNRIWSLEEQHASNMSLIKALKTELDRARVRIKE 185

Query: 1547 LLQEQQADRNEIDDLMKQIAEDKLFRKSKETDRIKSTLQSVRDELEDERKLRKRSESLHR 1368
            LL++QQA+R+E+DD+MKQIAEDKL RKSKE DR+ + +QS+RDELED+RKLRKRSESL R
Sbjct: 186  LLRDQQAERHEVDDIMKQIAEDKLARKSKEQDRLHAAIQSLRDELEDDRKLRKRSESLRR 245

Query: 1367 KLARELSETKSAFSRALKELERERKARTLLEDLCDEFATGIGDYEQEVRALRHKNEKDQG 1188
            KLARELSE KS+FS ALK++ERERK+R LLEDLCDEFA GI DYE EV AL  K+++D  
Sbjct: 246  KLARELSEVKSSFSNALKDMERERKSRKLLEDLCDEFAKGIKDYEHEVHALNKKSDRDWV 305

Query: 1187 GKDDQDRLIVHISEAWLDERLQMKLAEAQCDVSEKNTIVDKLSFEIETFLKAKRSGNLNR 1008
            G+DD D LI+HISE WLDER+QM+L EAQ   SE N+IVDKL FEIETFLK K  GN   
Sbjct: 306  GRDDGDHLILHISETWLDERMQMRLEEAQHGFSENNSIVDKLGFEIETFLKTKGMGNFKC 365

Query: 1007 NEISPSRDSKKHKNLRRHSLESVHFLGATSAPQDVGDEEDSVGSDSHCFELVNKNMGDKA 828
             E             RR+S+ESV      SAPQDVGDEEDS GSDSHCFEL   + GD  
Sbjct: 366  RE-------------RRNSMESVPLNEVVSAPQDVGDEEDSTGSDSHCFELNKPSNGD-- 410

Query: 827  TGSISKPKLHELGEEAVEDDELGETRKPNYVKKKPGTGERTKARNPSGSKTQFEEQIKRA 648
                     H   +EAV      E  K    KKK  + ERT+ +NP+  + +FEE + +A
Sbjct: 411  --------FHLHKDEAVA-GHTEEMDKSALTKKKLASLERTRGQNPANLQVKFEEHMAQA 461

Query: 647  MSSNEN-KSQFLNREDKKGGEEADPVEISISQKSENCEATNEKKLRNDGIHGSHSNNVIE 471
            M+ N N KSQ ++ E+ K GE                  + E+K + + IHGS+SN VI+
Sbjct: 462  MTYNGNKKSQVMDLEEVKTGE----------------GGSLERKSKPEEIHGSNSNYVID 505

Query: 470  GLLRRSRMLLADGGRKEIHSEDDGVEDSGAW--RGIASPVQQWVSRFAAPDLEISESSSQ 297
              ++     ++      +H E+D  E S ++  R  ASPV++W+S+    DL+ISE S++
Sbjct: 506  NSIKSH---ISSSEAVNLHLENDAGEASCSYPPRRNASPVRRWMSKLTTSDLDISEPSTK 562

Query: 296  WAPSLKGNTLKARLMEARLEGQHSRLKASKG 204
               +LK NTLKA+L+EAR +G  SRLK  KG
Sbjct: 563  QPTNLKENTLKAKLLEARSKGSRSRLKIFKG 593