BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Coptis21_contig00011004
         (2167 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002275567.1| PREDICTED: cell surface receptor daf-1 [Viti...   900   0.0  
ref|XP_002526619.1| protein kinase, putative [Ricinus communis] ...   886   0.0  
ref|XP_004143168.1| PREDICTED: probable LIM domain-containing se...   790   0.0  
ref|XP_003544895.1| PREDICTED: mitogen-activated protein kinase ...   789   0.0  
ref|XP_003519263.1| PREDICTED: focal adhesion kinase 1-like [Gly...   780   0.0  

>ref|XP_002275567.1| PREDICTED: cell surface receptor daf-1 [Vitis vinifera]
            gi|297745851|emb|CBI15907.3| unnamed protein product
            [Vitis vinifera]
          Length = 592

 Score =  900 bits (2326), Expect = 0.0
 Identities = 435/574 (75%), Positives = 504/574 (87%), Gaps = 3/574 (0%)
 Frame = +1

Query: 157  AAALECWSGRASTDEDMVEQVLMKTQDRSEEVLXXXXXXXXXXXFKDSSVMQKKLQKLKC 336
            AAALECWS RASTDEDMVEQVLM+TQDRSE +             K+SS MQK+LQ+L  
Sbjct: 2    AAALECWSSRASTDEDMVEQVLMRTQDRSEGL----PENSSGAGVKESSAMQKRLQRLSR 57

Query: 337  NVSEAITNLKNSLNLDSVRGPQGSKIETCRKLVWGGVVKNLTQLYPGSQLPEKLISNIRK 516
            NVSEAI +LKNSLNLDS R P  SKIE+CRKLVWGGVV+NLTQLYPGSQLPEKL+SNIRK
Sbjct: 58   NVSEAIASLKNSLNLDSPRDPPASKIESCRKLVWGGVVRNLTQLYPGSQLPEKLVSNIRK 117

Query: 517  HFDSLPVSYAQADFDMKDVFLHIKLIEQAAIDEHQAILIQEVSDDETQGFVFKLTFACNS 696
            H+DSLP+SYAQA FDMKDVFLHI++IEQA++D+H AILIQEVSDDE QG VFKLTFACNS
Sbjct: 118  HYDSLPLSYAQAGFDMKDVFLHIRMIEQASVDDHPAILIQEVSDDEIQGSVFKLTFACNS 177

Query: 697  SISWPTMSGALDNASICCKKIQIFEKKGFTLGIVLVLVQSGYEKSFKSRIENALKSALKK 876
            SISWP MSGALD+ASICCKKIQIFEKKGFTLGI+L+LVQ+G EKSF++RIENALK A+KK
Sbjct: 178  SISWPAMSGALDSASICCKKIQIFEKKGFTLGIILLLVQAGQEKSFQNRIENALKFAIKK 237

Query: 877  PKP--MKLPFGFCGCQEENTKGQEVGDADENDSH-NYENGIEHSNFNIQLQMPLPNTSSL 1047
             KP  +KLPFG CGCQEENTKG+EVG+ +E     ++ NGI++SN  +QLQMPLP +S +
Sbjct: 238  SKPTTVKLPFGLCGCQEENTKGREVGEIEEEGGEPHHRNGIDNSNTKVQLQMPLPTSSFV 297

Query: 1048 VSVDEWQTIRSGGDKIGKWLFSSDEIEFTDQIGLNSFKGVYKGKRVAIEKLRGSERGNAF 1227
            VSVDEWQT++SGG++IGKWL +SD +EF DQIG NSFKGVYKGKRV IEKL+G ++GN++
Sbjct: 298  VSVDEWQTVQSGGEEIGKWLLNSDNLEFVDQIGPNSFKGVYKGKRVGIEKLKGCDKGNSY 357

Query: 1228 EFEIRRDLLELMTCGHKSILQFHGVCIDENHGLCVVTKIMEGGSVHDLLQNSKKLQAKDI 1407
            EFE+R+DLLELMTCGHK+ILQF GVC+DENHGLCVVTK+MEGGSVHD++  +KK Q K+I
Sbjct: 358  EFELRKDLLELMTCGHKNILQFFGVCVDENHGLCVVTKLMEGGSVHDVILKNKKFQNKEI 417

Query: 1408 IRVAVDIAEGLMFMNDHGVVYGDLNTHRILLDRQGNACVGNMGIVTVCMNNGEVTEYEMD 1587
            IR+A+D+AEG+ FMNDHGV Y DLNT R+LLDR GNAC+G+MGIVT C + GE  EYE D
Sbjct: 418  IRIAIDVAEGIKFMNDHGVAYRDLNTQRVLLDRHGNACLGDMGIVTACKSVGEAMEYETD 477

Query: 1588 GYRWVAPEIIAGDPESVTETWMSNVYSFGMVVWEMVAGEAAYAALSPVQAAVGIAACGLR 1767
            GYRW+APEIIAGDPESVTET MSNVYSFGMV+WEMV GEAAY+A SPVQAAVGIAACGLR
Sbjct: 478  GYRWLAPEIIAGDPESVTETLMSNVYSFGMVLWEMVTGEAAYSAYSPVQAAVGIAACGLR 537

Query: 1768 PDIPKDCPQILRSVMTKCWNSCPSKRPQFSEILA 1869
            P+IPKDCPQILRS+MTKCWN+CPSKRPQFSEIL+
Sbjct: 538  PEIPKDCPQILRSLMTKCWNNCPSKRPQFSEILS 571


>ref|XP_002526619.1| protein kinase, putative [Ricinus communis]
            gi|223534059|gb|EEF35778.1| protein kinase, putative
            [Ricinus communis]
          Length = 609

 Score =  886 bits (2289), Expect = 0.0
 Identities = 433/598 (72%), Positives = 501/598 (83%), Gaps = 27/598 (4%)
 Frame = +1

Query: 157  AAALECWSGRASTDEDMVEQVLMKTQDRSEEVLXXXXXXXXXXXFK-------DSSVMQK 315
            AAALECWS RASTDEDMVEQVLM+TQDRSE  L                     SS MQK
Sbjct: 2    AAALECWSSRASTDEDMVEQVLMRTQDRSESTLLHQDTTSSLSSLNPVIKDPPSSSNMQK 61

Query: 316  KLQKLKCNVSEAITNLKNSLNLDSVRGPQ-----------------GSKIETCRKLVWGG 444
            +LQ+L  NVSEAI +LKNSLNLDS RG                    +K+E+CRK+VW G
Sbjct: 62   RLQRLSRNVSEAIASLKNSLNLDSPRGDSVLQLQQQQQQLPLQVNGSTKVESCRKVVWAG 121

Query: 445  VVKNLTQLYPGSQLPEKLISNIRKHFDSLPVSYAQADFDMKDVFLHIKLIEQAAIDEHQA 624
            VV+NLTQLYPGSQLPEKL+SNIRKH+DSLP+SYAQA FDMKDVFLHIKLIEQA++DE  A
Sbjct: 122  VVRNLTQLYPGSQLPEKLVSNIRKHYDSLPLSYAQAGFDMKDVFLHIKLIEQASVDEQPA 181

Query: 625  ILIQEVSDDETQGFVFKLTFACNSSISWPTMSGALDNASICCKKIQIFEKKGFTLGIVLV 804
            I+IQEVSDDE QG VFKLTFACNS ISWP MSGALDNASICCKKIQIFEKKGFTL ++L+
Sbjct: 182  IMIQEVSDDEVQGSVFKLTFACNSLISWPAMSGALDNASICCKKIQIFEKKGFTLAVILL 241

Query: 805  LVQSGYEKSFKSRIENALKSALKKPKP--MKLPFGFCGCQEENTKGQEVGDADENDSH-N 975
            LVQ+G+EKSFK+RIENALK+A+KKPK   +KLPFG CGCQEENT+G++ G+ +E+ +  +
Sbjct: 242  LVQAGHEKSFKNRIENALKNAIKKPKQTTVKLPFGLCGCQEENTRGRDFGEIEEDPNELS 301

Query: 976  YENGIEHSNFNIQLQMPLPNTSSLVSVDEWQTIRSGGDKIGKWLFSSDEIEFTDQIGLNS 1155
            Y NG E+ N  IQL+MPLP +S +VS+DEWQT++SGGD+IGKWL +SD +EF DQIG NS
Sbjct: 302  YRNGTENLNVKIQLEMPLPTSSFVVSIDEWQTMQSGGDEIGKWLLNSDNLEFVDQIGPNS 361

Query: 1156 FKGVYKGKRVAIEKLRGSERGNAFEFEIRRDLLELMTCGHKSILQFHGVCIDENHGLCVV 1335
            FKGVYKGKRV IEKL+G ++GNA++FE+R+DLLELMTCGHK++LQF+GVC+DENHGLCVV
Sbjct: 362  FKGVYKGKRVGIEKLKGCDKGNAYDFELRKDLLELMTCGHKNVLQFYGVCVDENHGLCVV 421

Query: 1336 TKIMEGGSVHDLLQNSKKLQAKDIIRVAVDIAEGLMFMNDHGVVYGDLNTHRILLDRQGN 1515
            TK+MEGGSV DL+  +KKLQ K+IIR+AVDIAEG+ FMNDHGV Y DLNT RILLDR GN
Sbjct: 422  TKLMEGGSVSDLMLKNKKLQTKEIIRIAVDIAEGIKFMNDHGVAYRDLNTQRILLDRHGN 481

Query: 1516 ACVGNMGIVTVCMNNGEVTEYEMDGYRWVAPEIIAGDPESVTETWMSNVYSFGMVVWEMV 1695
            AC+G+MGIVT C + GE  EYE DGYRW+APEIIAGDPESVTETWMSNVYSFGMV+WEMV
Sbjct: 482  ACLGDMGIVTACKSMGEAMEYETDGYRWLAPEIIAGDPESVTETWMSNVYSFGMVIWEMV 541

Query: 1696 AGEAAYAALSPVQAAVGIAACGLRPDIPKDCPQILRSVMTKCWNSCPSKRPQFSEILA 1869
             GEAAYAA SPVQAAVGIAACGLRPDIPKDCPQIL+S+MTKCWN+CPSKRPQFSEIL+
Sbjct: 542  TGEAAYAACSPVQAAVGIAACGLRPDIPKDCPQILKSLMTKCWNNCPSKRPQFSEILS 599


>ref|XP_004143168.1| PREDICTED: probable LIM domain-containing serine/threonine-protein
            kinase DDB_G0287001-like [Cucumis sativus]
          Length = 585

 Score =  790 bits (2040), Expect = 0.0
 Identities = 383/576 (66%), Positives = 468/576 (81%), Gaps = 5/576 (0%)
 Frame = +1

Query: 157  AAALECWSGRASTDEDMVEQVLMKTQDRSEEVLXXXXXXXXXXXFKDSSVMQKKLQKLKC 336
            A ALECWS RASTDEDMVEQVLM+TQDRSE               K+SS M ++LQ+   
Sbjct: 2    ATALECWSSRASTDEDMVEQVLMRTQDRSE---GSKPDSSFAVGEKESSAMHRRLQRFSR 58

Query: 337  NVSEAITNLKNSLNLDSVRGPQGSKIETCRKLVWGGVVKNLTQLYPGSQLPEKLISNIRK 516
            NVSEA+ +LKNSLNLDS+R P  ++ E  +K VWG VV+NLTQLYPGSQLPEKL+SNIRK
Sbjct: 59   NVSEAVASLKNSLNLDSIRDPSPTRTEGSKKAVWGTVVRNLTQLYPGSQLPEKLVSNIRK 118

Query: 517  HFDSLPVSYAQADFDMKDVFLHIKLIEQAAIDEHQAILIQEVSDDETQGFVFKLTFACNS 696
            H+DSLP+SYA A FDMKDVFLHIKL+EQA++ +H AIL QEV++ + Q  + K TFACNS
Sbjct: 119  HYDSLPLSYALAGFDMKDVFLHIKLMEQASVYDHPAILFQEVTNRDVQKPIIKFTFACNS 178

Query: 697  SISWPTMSGALDNASICCKKIQIFEKKGFTLGIVLVLVQSGYEKSFKSRIENALKSALKK 876
            S+SW  MSGAL+ A+I C+KIQIFEKK FTLG++L +     EK FKS++ENALK A+KK
Sbjct: 179  SVSWSAMSGALETAAIRCEKIQIFEKKKFTLGVILFVNLDLQEKLFKSKVENALKLAIKK 238

Query: 877  PKP--MKLPFGFCGCQEENTKGQEVGDADENDSH-NYENGIEHSNF--NIQLQMPLPNTS 1041
            PK   +KLPFGFCGCQE NT G+++ + +E+    N  +G E+SN   N+Q++MPL  +S
Sbjct: 239  PKTTAVKLPFGFCGCQEGNTGGKDLRETEEDGVEPNCRSGFENSNLSENLQIEMPLCTSS 298

Query: 1042 SLVSVDEWQTIRSGGDKIGKWLFSSDEIEFTDQIGLNSFKGVYKGKRVAIEKLRGSERGN 1221
              V+VDEWQTI+SGG+++GKWL SS+ +EF DQ+G NSFKGVYKG+RVAIEK++G E+G 
Sbjct: 299  FAVTVDEWQTIQSGGNELGKWLLSSENLEFVDQMGPNSFKGVYKGRRVAIEKIKGCEKGV 358

Query: 1222 AFEFEIRRDLLELMTCGHKSILQFHGVCIDENHGLCVVTKIMEGGSVHDLLQNSKKLQAK 1401
            +++FE+R+DLLELMTCGHK+IL F+GVCIDENHGLCVVTK+MEGGSVH+L+  +KKLQ K
Sbjct: 359  SYKFELRKDLLELMTCGHKNILMFYGVCIDENHGLCVVTKLMEGGSVHELMLKNKKLQTK 418

Query: 1402 DIIRVAVDIAEGLMFMNDHGVVYGDLNTHRILLDRQGNACVGNMGIVTVCMNNGEVTEYE 1581
            +I R+A+DI EG+ FMNDHGV Y DLNT RILLD+ GNAC+G+MGI+T C N GE  EYE
Sbjct: 419  EITRIAIDIVEGIKFMNDHGVAYRDLNTQRILLDKNGNACLGDMGILTACKNLGEAMEYE 478

Query: 1582 MDGYRWVAPEIIAGDPESVTETWMSNVYSFGMVVWEMVAGEAAYAALSPVQAAVGIAACG 1761
             DGYRW+APEIIAGDPESV ETWMSNVYS GMV+WEMV GEAAY A SPVQAAVGIAACG
Sbjct: 479  TDGYRWLAPEIIAGDPESVNETWMSNVYSLGMVIWEMVTGEAAYGAYSPVQAAVGIAACG 538

Query: 1762 LRPDIPKDCPQILRSVMTKCWNSCPSKRPQFSEILA 1869
            LRPD+PKDC   L+S+M +CWN+CPSKRPQFSEIL+
Sbjct: 539  LRPDVPKDCSSTLKSLMIRCWNNCPSKRPQFSEILS 574


>ref|XP_003544895.1| PREDICTED: mitogen-activated protein kinase kinase kinase 10-like
            [Glycine max]
          Length = 590

 Score =  789 bits (2037), Expect = 0.0
 Identities = 390/582 (67%), Positives = 469/582 (80%), Gaps = 11/582 (1%)
 Frame = +1

Query: 157  AAALECWSGRA------STDEDMVEQVLMKTQDRSEEVLXXXXXXXXXXXFKDSSV-MQK 315
            AAALECWS R       STD+D VEQVLM+T  RSE                 S++ + K
Sbjct: 2    AAALECWSSRTTAAAATSTDDDTVEQVLMRTHHRSEGTTTTSTPNNNNNKDPSSAIPVHK 61

Query: 316  KLQKLKCNVSEAITNLKNSLNLDSVRGPQGSKIE-TCRKLVWGGVVKNLTQLYPGSQLPE 492
            KLQKL  NVSEAI + +NSLNLDS   P  SK + + RKL WG VV+NLTQLYPGSQLPE
Sbjct: 62   KLQKLTRNVSEAIASFRNSLNLDS---PPSSKADASSRKLAWGSVVRNLTQLYPGSQLPE 118

Query: 493  KLISNIRKHFDSLPVSYAQADFDMKDVFLHIKLIEQAAIDEHQAILIQEVSDDETQGFVF 672
            KL+SNIRKH+DSLP+SYAQA+FDMKDVFLHIKL+EQA+  +  AILIQE  D E QG   
Sbjct: 119  KLMSNIRKHYDSLPLSYAQAEFDMKDVFLHIKLMEQASESDQPAILIQEECDYEVQGSAL 178

Query: 673  KLTFACNSSISWPTMSGALDNASICCKKIQIFEKKGFTLGIVLVLVQSGYEKSFKSRIEN 852
            +LTFACNS ISWP MSGALD++SICCK++QIFEKKGFTLG+VL++VQSG++K  ++R+E+
Sbjct: 179  RLTFACNSPISWPAMSGALDSSSICCKRMQIFEKKGFTLGVVLLVVQSGHDKLVRTRVES 238

Query: 853  ALKSALKKPKP--MKLPFGFCGCQEENTKGQEVGDADENDSHNYENG-IEHSNFNIQLQM 1023
            ALK A+K+PK   +KLPFG CGCQEEN+KG ++ + +E  S  Y     E+S   IQLQ+
Sbjct: 239  ALKFAMKRPKTGAVKLPFGLCGCQEENSKGGDLVEIEEEISDGYRGKEFENSGQRIQLQV 298

Query: 1024 PLPNTSSLVSVDEWQTIRSGGDKIGKWLFSSDEIEFTDQIGLNSFKGVYKGKRVAIEKLR 1203
            PLP++S +VSVDEWQTI+SGGD+I KWL +SD +EF +QIG NSFKGVY GKRV IEKL+
Sbjct: 299  PLPSSSFVVSVDEWQTIKSGGDEIEKWLLNSDSVEFVEQIGPNSFKGVYLGKRVKIEKLK 358

Query: 1204 GSERGNAFEFEIRRDLLELMTCGHKSILQFHGVCIDENHGLCVVTKIMEGGSVHDLLQNS 1383
            G ++GN++EFE+ +DLLELMTCGH++ILQF G+C+D+NHGLCVVTK MEGGSVHDL+  +
Sbjct: 359  GCDKGNSYEFELHKDLLELMTCGHRNILQFCGICVDDNHGLCVVTKFMEGGSVHDLMMKN 418

Query: 1384 KKLQAKDIIRVAVDIAEGLMFMNDHGVVYGDLNTHRILLDRQGNACVGNMGIVTVCMNNG 1563
            KKLQ KDI+R+AVD+AEG+ FMNDHGV Y DLNT RILLDR GNAC+G+MGIVT C + G
Sbjct: 419  KKLQTKDIVRIAVDVAEGIKFMNDHGVAYRDLNTPRILLDRHGNACLGDMGIVTACKSVG 478

Query: 1564 EVTEYEMDGYRWVAPEIIAGDPESVTETWMSNVYSFGMVVWEMVAGEAAYAALSPVQAAV 1743
            E  EYE DGYRW+APEIIAGDPE+VTETWMSNVYSFGMV+WEMV GE AY++ SPVQAAV
Sbjct: 479  EAMEYETDGYRWLAPEIIAGDPENVTETWMSNVYSFGMVIWEMVTGETAYSSFSPVQAAV 538

Query: 1744 GIAACGLRPDIPKDCPQILRSVMTKCWNSCPSKRPQFSEILA 1869
            GIAACGLRP+IPKDC Q L+ +MTKCWN+ PSKRP FSEILA
Sbjct: 539  GIAACGLRPEIPKDCQQTLKYIMTKCWNNNPSKRPHFSEILA 580


>ref|XP_003519263.1| PREDICTED: focal adhesion kinase 1-like [Glycine max]
          Length = 588

 Score =  780 bits (2015), Expect = 0.0
 Identities = 381/580 (65%), Positives = 465/580 (80%), Gaps = 9/580 (1%)
 Frame = +1

Query: 157  AAALECWSGR------ASTDEDMVEQVLMKTQDRSEEVLXXXXXXXXXXXFKDSSVMQKK 318
            AAALECWS R      A+TD+D VEQVLM+T  RSE                 +  + KK
Sbjct: 2    AAALECWSSRTTTSAAAATDDDTVEQVLMRTHHRSEGTTTTSTHNNKDN-LPSAIPVHKK 60

Query: 319  LQKLKCNVSEAITNLKNSLNLDSVRGPQGSKIETCRKLVWGGVVKNLTQLYPGSQLPEKL 498
            LQKL  NVSEAI + +NSLNLDS   P  +   + RKL WG VV+NLTQLYPGSQLPEKL
Sbjct: 61   LQKLTRNVSEAIASFRNSLNLDSP--PSSNADASSRKLAWGSVVRNLTQLYPGSQLPEKL 118

Query: 499  ISNIRKHFDSLPVSYAQADFDMKDVFLHIKLIEQAAIDEHQAILIQEVSDDETQGFVFKL 678
            +SNIRKH+DSLP+SYAQA+FDMK+VFLHIKL+EQA+  +  AILIQE  D E QG   +L
Sbjct: 119  MSNIRKHYDSLPLSYAQAEFDMKNVFLHIKLMEQASESDQPAILIQEECDGEIQGSALRL 178

Query: 679  TFACNSSISWPTMSGALDNASICCKKIQIFEKKGFTLGIVLVLVQSGYEKSFKSRIENAL 858
            TFACNS ISWP MSGALD++SICCK++QIFEKKGFTLG+VL++V  G++K  ++R+ENAL
Sbjct: 179  TFACNSPISWPAMSGALDSSSICCKRMQIFEKKGFTLGVVLLVVLPGHDKLVRTRVENAL 238

Query: 859  KSALKKPKP--MKLPFGFCGCQEENTKGQEVGDADENDSHNYENG-IEHSNFNIQLQMPL 1029
            K A+KKPK   +KLPFG CGCQEEN+KG+E+ + +E     Y     E+S+  IQLQ+PL
Sbjct: 239  KFAMKKPKTGAVKLPFGLCGCQEENSKGRELVEIEEETGDGYRGKEFENSSQRIQLQVPL 298

Query: 1030 PNTSSLVSVDEWQTIRSGGDKIGKWLFSSDEIEFTDQIGLNSFKGVYKGKRVAIEKLRGS 1209
            P++S +VSVDEWQTI+SGG++I KWL +SD +EF +QIG NS++GVY GKRV IEKL+G 
Sbjct: 299  PSSSFVVSVDEWQTIKSGGNEIEKWLLNSDSVEFVEQIGPNSYRGVYMGKRVGIEKLKGC 358

Query: 1210 ERGNAFEFEIRRDLLELMTCGHKSILQFHGVCIDENHGLCVVTKIMEGGSVHDLLQNSKK 1389
            ++GN++EFE+ +DLLELMTCGH++ILQF G+C+D+NHGLCVVTK MEGGSVHDL+  +KK
Sbjct: 359  DKGNSYEFELHKDLLELMTCGHRNILQFCGICVDDNHGLCVVTKFMEGGSVHDLMMKNKK 418

Query: 1390 LQAKDIIRVAVDIAEGLMFMNDHGVVYGDLNTHRILLDRQGNACVGNMGIVTVCMNNGEV 1569
            LQ KD++R+AVD+AEG+ FMNDHGV Y DLNT  ILLD+ GNAC+G+MGIVT C + GE 
Sbjct: 419  LQTKDVVRIAVDVAEGIKFMNDHGVAYRDLNTRGILLDKHGNACLGDMGIVTACKSVGEA 478

Query: 1570 TEYEMDGYRWVAPEIIAGDPESVTETWMSNVYSFGMVVWEMVAGEAAYAALSPVQAAVGI 1749
             EYE DGYRW+APEIIAGDPE+VTETWMSNVYSFGMV+WEMV GEAAY++ SPVQAAVGI
Sbjct: 479  MEYETDGYRWLAPEIIAGDPENVTETWMSNVYSFGMVIWEMVTGEAAYSSFSPVQAAVGI 538

Query: 1750 AACGLRPDIPKDCPQILRSVMTKCWNSCPSKRPQFSEILA 1869
            AACGLRP+IPKDC Q L+ +MTKCWN+ PSKRP FSEILA
Sbjct: 539  AACGLRPEIPKDCQQTLKHIMTKCWNNTPSKRPHFSEILA 578