BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Coptis21_contig00002501
         (2283 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002281463.1| PREDICTED: high affinity cationic amino acid...   836   0.0  
ref|XP_002869906.1| hypothetical protein ARALYDRAFT_329490 [Arab...   806   0.0  
ref|NP_193844.2| amino acid transporter 1 [Arabidopsis thaliana]...   804   0.0  
ref|XP_004135553.1| PREDICTED: cationic amino acid transporter 1...   797   0.0  
ref|XP_002526614.1| cationic amino acid transporter, putative [R...   791   0.0  

>ref|XP_002281463.1| PREDICTED: high affinity cationic amino acid transporter 1-like
            isoform 1 [Vitis vinifera]
            gi|359483932|ref|XP_003633038.1| PREDICTED: high affinity
            cationic amino acid transporter 1-like isoform 2 [Vitis
            vinifera]
          Length = 606

 Score =  836 bits (2160), Expect = 0.0
 Identities = 417/577 (72%), Positives = 466/577 (80%)
 Frame = -2

Query: 1940 KRRGCSCSKDDFLPEESFQSWGNYGKAWKEVGFRLKDRILTRSLDETELNEMKARSQHDM 1761
            +RRGCSCSKDDFLPEESF++WGNYG+A  E+  RLKDR+LTRSLD TE+NE+KARS H+M
Sbjct: 10   RRRGCSCSKDDFLPEESFKTWGNYGRALAEIPARLKDRLLTRSLDTTEMNEIKARSAHEM 69

Query: 1760 KKTLNWWDLIWFGIGAVIGSGIFVLTGQEAKLTVGPAVVLSYAISGLSAMLSVFCYTEFA 1581
            KKTL WWDL+WFGIGAVIG+GIFVLTG +A+   GPAVVLSY +SG+SAMLSVFCYTEFA
Sbjct: 70   KKTLTWWDLMWFGIGAVIGAGIFVLTGIQARDVAGPAVVLSYVVSGISAMLSVFCYTEFA 129

Query: 1580 VEIPAAGGSFAYLRVELGDFMAFIAAGNILFEYVIGGAAVSRSWTSYFATLINQKSDFFL 1401
            VEIP AGGSFAYLRVELGDFMAFIAAGNIL EYVIGGAAV+RSWTSYFATL N K + F 
Sbjct: 130  VEIPVAGGSFAYLRVELGDFMAFIAAGNILLEYVIGGAAVARSWTSYFATLCNHKPEDFR 189

Query: 1400 IHAPALAKGYNMLDPLAVGVIALICILAVKSTKGSSRLNYIASXXXXXXXXXXXIAGFIK 1221
            I A +L + YN LDP+AVGVI +IC+LAV STKGSSR NYIAS           IAG  K
Sbjct: 190  IIAHSLKEDYNQLDPIAVGVITIICLLAVFSTKGSSRFNYIASIFHVIVILFIIIAGLCK 249

Query: 1220 GKTENYTPFTPFGARGIFSASATLFFAYVGFDAVSTMAEETKNPARDIPIGLVGSMVITT 1041
              T NYTPF P G RGIF +SA LFFAY+GFDAVSTMAEETKNP RDIPIGLVGSM ITT
Sbjct: 250  ADTSNYTPFAPNGVRGIFKSSAVLFFAYIGFDAVSTMAEETKNPGRDIPIGLVGSMSITT 309

Query: 1040 TVYCLMAVSLCLMQSYTDIDENAPFSVAFEHVGMNWAKYVVALGALKGMTTVLLVGAIGQ 861
              YCL+AV+LCLMQ YTDID++APFSVAFE VG NWAKY+VA GALKGMTTVLLV A+GQ
Sbjct: 310  LAYCLLAVTLCLMQKYTDIDKDAPFSVAFEAVGWNWAKYIVAAGALKGMTTVLLVSAVGQ 369

Query: 860  ARYLTHIARTHMISPWFANVDEKTGTPXXXXXXXXXXXXXXAFFTKLSILGDLLSISTLF 681
            ARYLTHIARTHM+ PW A+V+ +TGTP              AFFT L IL +LLSISTLF
Sbjct: 370  ARYLTHIARTHMMPPWLAHVNSRTGTPVNATIVMLVATAIIAFFTDLGILSNLLSISTLF 429

Query: 680  IFMLVAVALLVRRYYASGTTTPADRNKFLICLALILGSSIATAIYWATQGNEWVGYLITV 501
            IFMLVAV LLVRRYY S  TTP +RNK ++CL LI+GSSIATA YW      WVGY++TV
Sbjct: 430  IFMLVAVGLLVRRYYVSNVTTPTNRNKLIVCLVLIIGSSIATATYWGLSETGWVGYVVTV 489

Query: 500  PIWLAATVGLRVFVPQARSPKLWGVPLVPWLPSLSIAMNIFLLGSIDGVAFERFSMWTIV 321
            PIWL ATV L  FVP+AR PKLWGVPLVPWLPS SIA+NIFLLGSID  +FERF +WT V
Sbjct: 490  PIWLLATVALWAFVPKAREPKLWGVPLVPWLPSASIAINIFLLGSIDKASFERFGIWTAV 549

Query: 320  LLLYYFFVGLHASYDTAKQSLMEKEQNITQLKKAEEG 210
            L++YYFF GLHASYDTAK+S     +  TQ KK EEG
Sbjct: 550  LMVYYFFFGLHASYDTAKESAKVTHET-TQYKKVEEG 585


>ref|XP_002869906.1| hypothetical protein ARALYDRAFT_329490 [Arabidopsis lyrata subsp.
            lyrata] gi|297315742|gb|EFH46165.1| hypothetical protein
            ARALYDRAFT_329490 [Arabidopsis lyrata subsp. lyrata]
          Length = 599

 Score =  806 bits (2083), Expect = 0.0
 Identities = 403/577 (69%), Positives = 459/577 (79%)
 Frame = -2

Query: 1940 KRRGCSCSKDDFLPEESFQSWGNYGKAWKEVGFRLKDRILTRSLDETELNEMKARSQHDM 1761
            +RRGCSC+KDDFLPEESFQS GNY KA KE   R  DRI+TRSLD  E+NEMKARS H+M
Sbjct: 13   RRRGCSCTKDDFLPEESFQSMGNYLKALKETPSRFMDRIMTRSLDSDEINEMKARSGHEM 72

Query: 1760 KKTLNWWDLIWFGIGAVIGSGIFVLTGQEAKLTVGPAVVLSYAISGLSAMLSVFCYTEFA 1581
            KKTL WWDL+WFGIGAVIGSGIFVLTG EA+   GPAVVLSY +SG+SAMLSVFCYTEFA
Sbjct: 73   KKTLTWWDLMWFGIGAVIGSGIFVLTGLEARNASGPAVVLSYVVSGVSAMLSVFCYTEFA 132

Query: 1580 VEIPAAGGSFAYLRVELGDFMAFIAAGNILFEYVIGGAAVSRSWTSYFATLINQKSDFFL 1401
            VEIP AGGSFAYLRVELGDFMAFIAAGNI+ EYV+GGAAV+RSWTSYFATL+N K + F 
Sbjct: 133  VEIPVAGGSFAYLRVELGDFMAFIAAGNIILEYVVGGAAVARSWTSYFATLLNHKPEDFR 192

Query: 1400 IHAPALAKGYNMLDPLAVGVIALICILAVKSTKGSSRLNYIASXXXXXXXXXXXIAGFIK 1221
            I A +L + Y+ LDP+AVGV A+IC+LAV  TKGSSR NYIAS           IAGF K
Sbjct: 193  IIAHSLGEDYSHLDPIAVGVCAIICVLAVLGTKGSSRFNYIASIIHMVVILFVIIAGFTK 252

Query: 1220 GKTENYTPFTPFGARGIFSASATLFFAYVGFDAVSTMAEETKNPARDIPIGLVGSMVITT 1041
               +NY+ FTP+G RG+F ++A LFFAY+GFDAVSTMAEETKNP RDIPIGLVGSMV+TT
Sbjct: 253  ADVKNYSDFTPYGVRGVFKSAAVLFFAYIGFDAVSTMAEETKNPGRDIPIGLVGSMVVTT 312

Query: 1040 TVYCLMAVSLCLMQSYTDIDENAPFSVAFEHVGMNWAKYVVALGALKGMTTVLLVGAIGQ 861
              YCLMAV+LCLMQ Y  ID +APFSVAF  VG +WAKY+VA GALKGMTTVLLVGAIGQ
Sbjct: 313  VCYCLMAVALCLMQPYQQIDPDAPFSVAFSAVGWDWAKYIVAFGALKGMTTVLLVGAIGQ 372

Query: 860  ARYLTHIARTHMISPWFANVDEKTGTPXXXXXXXXXXXXXXAFFTKLSILGDLLSISTLF 681
            ARY+THIAR HM+ PW A V+ KTGTP              AFFTKL IL DLLS+STLF
Sbjct: 373  ARYMTHIARAHMMPPWLAQVNAKTGTPINATVVMLAATALIAFFTKLKILADLLSVSTLF 432

Query: 680  IFMLVAVALLVRRYYASGTTTPADRNKFLICLALILGSSIATAIYWATQGNEWVGYLITV 501
            IFM VAVALLVRRYY +G T+  DRNKFL+ L LIL SS AT +YWA +   W+GY ITV
Sbjct: 433  IFMFVAVALLVRRYYVTGETSSRDRNKFLVLLGLILASSTATGVYWALEKEGWIGYCITV 492

Query: 500  PIWLAATVGLRVFVPQARSPKLWGVPLVPWLPSLSIAMNIFLLGSIDGVAFERFSMWTIV 321
            PIW  +TVG++  VPQAR+PK+WGVPLVPWLPS SIA+NIFLLGSID  +F RF++WT +
Sbjct: 493  PIWFLSTVGMKFLVPQARAPKIWGVPLVPWLPSASIAINIFLLGSIDKKSFVRFAIWTGI 552

Query: 320  LLLYYFFVGLHASYDTAKQSLMEKEQNITQLKKAEEG 210
            LL+YY   GLHA+YDTAK +L EK      L+KAEEG
Sbjct: 553  LLVYYVLFGLHATYDTAKATLKEK----LTLQKAEEG 585


>ref|NP_193844.2| amino acid transporter 1 [Arabidopsis thaliana]
            gi|75297892|sp|Q84MA5.1|CAAT1_ARATH RecName:
            Full=Cationic amino acid transporter 1; AltName:
            Full=Amino acid transporter 1 gi|30102670|gb|AAP21253.1|
            At4g21120 [Arabidopsis thaliana]
            gi|110743257|dbj|BAE99519.1| amino acid transport protein
            AAT1 [Arabidopsis thaliana] gi|332659005|gb|AEE84405.1|
            amino acid transporter 1 [Arabidopsis thaliana]
          Length = 594

 Score =  804 bits (2076), Expect = 0.0
 Identities = 402/577 (69%), Positives = 458/577 (79%)
 Frame = -2

Query: 1940 KRRGCSCSKDDFLPEESFQSWGNYGKAWKEVGFRLKDRILTRSLDETELNEMKARSQHDM 1761
            +RRGCSC+KDDFLPEESFQS GNY KA KE   R  DRI+TRSLD  E+NEMKARS H+M
Sbjct: 11   RRRGCSCTKDDFLPEESFQSMGNYLKALKETPSRFMDRIMTRSLDSDEINEMKARSGHEM 70

Query: 1760 KKTLNWWDLIWFGIGAVIGSGIFVLTGQEAKLTVGPAVVLSYAISGLSAMLSVFCYTEFA 1581
            KKTL WWDL+WFGIGAVIGSGIFVLTG EA+   GPAVVLSY +SG+SAMLSVFCYTEFA
Sbjct: 71   KKTLTWWDLMWFGIGAVIGSGIFVLTGLEARNHSGPAVVLSYVVSGVSAMLSVFCYTEFA 130

Query: 1580 VEIPAAGGSFAYLRVELGDFMAFIAAGNILFEYVIGGAAVSRSWTSYFATLINQKSDFFL 1401
            VEIP AGGSFAYLRVELGDFMAFIAAGNI+ EYV+GGAAV+RSWTSYFATL+N K + F 
Sbjct: 131  VEIPVAGGSFAYLRVELGDFMAFIAAGNIILEYVVGGAAVARSWTSYFATLLNHKPEDFR 190

Query: 1400 IHAPALAKGYNMLDPLAVGVIALICILAVKSTKGSSRLNYIASXXXXXXXXXXXIAGFIK 1221
            I    L + Y+ LDP+AVGV A+IC+LAV  TKGSSR NYIAS           IAGF K
Sbjct: 191  IIVHKLGEDYSHLDPIAVGVCAIICVLAVVGTKGSSRFNYIASIIHMVVILFVIIAGFTK 250

Query: 1220 GKTENYTPFTPFGARGIFSASATLFFAYVGFDAVSTMAEETKNPARDIPIGLVGSMVITT 1041
               +NY+ FTP+G RG+F ++A LFFAY+GFDAVSTMAEETKNP RDIPIGLVGSMV+TT
Sbjct: 251  ADVKNYSDFTPYGVRGVFKSAAVLFFAYIGFDAVSTMAEETKNPGRDIPIGLVGSMVVTT 310

Query: 1040 TVYCLMAVSLCLMQSYTDIDENAPFSVAFEHVGMNWAKYVVALGALKGMTTVLLVGAIGQ 861
              YCLMAV+LCLMQ Y  ID +APFSVAF  VG +WAKY+VA GALKGMTTVLLVGAIGQ
Sbjct: 311  VCYCLMAVTLCLMQPYQQIDPDAPFSVAFSAVGWDWAKYIVAFGALKGMTTVLLVGAIGQ 370

Query: 860  ARYLTHIARTHMISPWFANVDEKTGTPXXXXXXXXXXXXXXAFFTKLSILGDLLSISTLF 681
            ARY+THIAR HM+ PW A V+ KTGTP              AFFTKL IL DLLS+STLF
Sbjct: 371  ARYMTHIARAHMMPPWLAQVNAKTGTPINATVVMLAATALIAFFTKLKILADLLSVSTLF 430

Query: 680  IFMLVAVALLVRRYYASGTTTPADRNKFLICLALILGSSIATAIYWATQGNEWVGYLITV 501
            IFM VAVALLVRRYY +G T+  DRNKFL+ L LIL SS ATA+YWA +   W+GY ITV
Sbjct: 431  IFMFVAVALLVRRYYVTGETSTRDRNKFLVFLGLILASSTATAVYWALEEEGWIGYCITV 490

Query: 500  PIWLAATVGLRVFVPQARSPKLWGVPLVPWLPSLSIAMNIFLLGSIDGVAFERFSMWTIV 321
            PIW  +TV ++  VPQAR+PK+WGVPLVPWLPS SIA+NIFLLGSID  +F RF++WT +
Sbjct: 491  PIWFLSTVAMKFLVPQARAPKIWGVPLVPWLPSASIAINIFLLGSIDTKSFVRFAIWTGI 550

Query: 320  LLLYYFFVGLHASYDTAKQSLMEKEQNITQLKKAEEG 210
            LL+YY   GLHA+YDTAK +L EK+     L+KAEEG
Sbjct: 551  LLIYYVLFGLHATYDTAKATLKEKQ----ALQKAEEG 583


>ref|XP_004135553.1| PREDICTED: cationic amino acid transporter 1-like [Cucumis sativus]
          Length = 582

 Score =  797 bits (2059), Expect = 0.0
 Identities = 392/560 (70%), Positives = 450/560 (80%)
 Frame = -2

Query: 1940 KRRGCSCSKDDFLPEESFQSWGNYGKAWKEVGFRLKDRILTRSLDETELNEMKARSQHDM 1761
            +RR C C K+DFLPEESFQSWGNY  A K   FRL +R+  RS ++TEL EMKARS+H+M
Sbjct: 12   RRRSCGCGKEDFLPEESFQSWGNYANALKATPFRLMNRLTARSAEQTELVEMKARSEHEM 71

Query: 1760 KKTLNWWDLIWFGIGAVIGSGIFVLTGQEAKLTVGPAVVLSYAISGLSAMLSVFCYTEFA 1581
            KK L WWDLIWFG+GAVIG+GIFVLTG E +   GPAVVLSY +SG+SAMLSVFCYTEFA
Sbjct: 72   KKNLTWWDLIWFGVGAVIGAGIFVLTGLETRKHAGPAVVLSYVVSGVSAMLSVFCYTEFA 131

Query: 1580 VEIPAAGGSFAYLRVELGDFMAFIAAGNILFEYVIGGAAVSRSWTSYFATLINQKSDFFL 1401
            VEIPAAGGSFAYLRVELGDF+AFIAAGNIL EYVIGGAAV+RSWTSYFATL N + + F 
Sbjct: 132  VEIPAAGGSFAYLRVELGDFVAFIAAGNILLEYVIGGAAVARSWTSYFATLCNHRPNDFR 191

Query: 1400 IHAPALAKGYNMLDPLAVGVIALICILAVKSTKGSSRLNYIASXXXXXXXXXXXIAGFIK 1221
            IH P+ A  YN LDP+AV VI +ICI AV STKGSSR NYIAS           IAG  K
Sbjct: 192  IHIPSFAHDYNRLDPIAVVVIIVICIFAVMSTKGSSRFNYIASILHVIVILFIVIAGLTK 251

Query: 1220 GKTENYTPFTPFGARGIFSASATLFFAYVGFDAVSTMAEETKNPARDIPIGLVGSMVITT 1041
               +N+TPF PFG RGIF ASA LFFAYVGFDAVST+AEETKNP +DIPIGLVGSMVITT
Sbjct: 252  ANPKNFTPFAPFGPRGIFVASAVLFFAYVGFDAVSTLAEETKNPGKDIPIGLVGSMVITT 311

Query: 1040 TVYCLMAVSLCLMQSYTDIDENAPFSVAFEHVGMNWAKYVVALGALKGMTTVLLVGAIGQ 861
            + YC++AV+LCLMQSY  IDE+APFSVAFE VG +WAKY+VA GA+KGMTTVLLV A+GQ
Sbjct: 312  SAYCILAVTLCLMQSYQQIDEDAPFSVAFEAVGWSWAKYIVAAGAIKGMTTVLLVSAVGQ 371

Query: 860  ARYLTHIARTHMISPWFANVDEKTGTPXXXXXXXXXXXXXXAFFTKLSILGDLLSISTLF 681
            ARYLTHIARTHM+SPWFA V+E+TGTP              AFFT L IL +LLSISTLF
Sbjct: 372  ARYLTHIARTHMVSPWFAKVNERTGTPVNATTSMMAATAVIAFFTTLEILSNLLSISTLF 431

Query: 680  IFMLVAVALLVRRYYASGTTTPADRNKFLICLALILGSSIATAIYWATQGNEWVGYLITV 501
            IFMLVAV L+VRRYY SG TTP +RNK +ICL LI+GSSI TA YWA+  + W+G+ +T+
Sbjct: 432  IFMLVAVGLIVRRYYVSGETTPLNRNKLIICLILIVGSSIGTAAYWASSDDGWIGFAVTL 491

Query: 500  PIWLAATVGLRVFVPQARSPKLWGVPLVPWLPSLSIAMNIFLLGSIDGVAFERFSMWTIV 321
            PIW  +T+ L + VPQA+ P++WGVPLVPWLPSLSIA+NIFLLGSID  +FERF +WT V
Sbjct: 492  PIWFLSTLALWLGVPQAKKPRVWGVPLVPWLPSLSIAINIFLLGSIDKASFERFGIWTGV 551

Query: 320  LLLYYFFVGLHASYDTAKQS 261
            LL+YY   GLHASYDTA +S
Sbjct: 552  LLVYYLLFGLHASYDTAMES 571


>ref|XP_002526614.1| cationic amino acid transporter, putative [Ricinus communis]
            gi|223534054|gb|EEF35773.1| cationic amino acid
            transporter, putative [Ricinus communis]
          Length = 587

 Score =  791 bits (2043), Expect = 0.0
 Identities = 396/577 (68%), Positives = 459/577 (79%)
 Frame = -2

Query: 1940 KRRGCSCSKDDFLPEESFQSWGNYGKAWKEVGFRLKDRILTRSLDETELNEMKARSQHDM 1761
            +RRGCSC+K DF+PEESFQS G+Y KA  E   R KDR+L RS+D TE+NE+KARS+H M
Sbjct: 12   RRRGCSCTKSDFIPEESFQSMGSYLKALSETPMRFKDRLLARSMDSTEINEIKARSEHQM 71

Query: 1760 KKTLNWWDLIWFGIGAVIGSGIFVLTGQEAKLTVGPAVVLSYAISGLSAMLSVFCYTEFA 1581
            KK L WWDLIWFGIGAVIG+GIFVLTG EA+   GPAVVLSY +SG+SAMLSVFCYTEFA
Sbjct: 72   KKNLTWWDLIWFGIGAVIGAGIFVLTGLEAQSVAGPAVVLSYVVSGISAMLSVFCYTEFA 131

Query: 1580 VEIPAAGGSFAYLRVELGDFMAFIAAGNILFEYVIGGAAVSRSWTSYFATLINQKSDFFL 1401
            VEIP AGGSFAYLRVELGDFMAFIAAGNIL EYVIGGAAV+R+WTSYFATL+N K + F 
Sbjct: 132  VEIPVAGGSFAYLRVELGDFMAFIAAGNILLEYVIGGAAVARAWTSYFATLLNHKPENFR 191

Query: 1400 IHAPALAKGYNMLDPLAVGVIALICILAVKSTKGSSRLNYIASXXXXXXXXXXXIAGFIK 1221
            I A +L + Y  LDP+AV VIA+IC+LAV STKGSSR NYIAS           IAG + 
Sbjct: 192  IIAHSLPEDYGHLDPIAVVVIAVICVLAVLSTKGSSRFNYIASIIHIVVILFIIIAGLVN 251

Query: 1220 GKTENYTPFTPFGARGIFSASATLFFAYVGFDAVSTMAEETKNPARDIPIGLVGSMVITT 1041
              T+NY  F P+GARG+F+ASA LFFAYVGFDAVSTMAEETK+PARDIPIGLVGSM +TT
Sbjct: 252  ADTKNYRDFAPYGARGVFNASAVLFFAYVGFDAVSTMAEETKDPARDIPIGLVGSMALTT 311

Query: 1040 TVYCLMAVSLCLMQSYTDIDENAPFSVAFEHVGMNWAKYVVALGALKGMTTVLLVGAIGQ 861
             +YCLMA++LCLM  Y  ID +APFSVAF+ VG  WAKY+V+LGALKGMTTVLLV A+GQ
Sbjct: 312  LLYCLMAITLCLMVPYKQIDPDAPFSVAFQSVGWGWAKYIVSLGALKGMTTVLLVSAVGQ 371

Query: 860  ARYLTHIARTHMISPWFANVDEKTGTPXXXXXXXXXXXXXXAFFTKLSILGDLLSISTLF 681
            ARYLTHIARTHM+ PW A+V+ KTGTP              AFFTKL +L +LLSISTLF
Sbjct: 372  ARYLTHIARTHMMPPWLAHVNAKTGTPVNATIVMLTATAVIAFFTKLEVLSNLLSISTLF 431

Query: 680  IFMLVAVALLVRRYYASGTTTPADRNKFLICLALILGSSIATAIYWATQGNEWVGYLITV 501
            IFMLVA+ALLVRRYY SG TT A+R K  +CL +IL +SIA A  W  Q + W+GY ITV
Sbjct: 432  IFMLVALALLVRRYYVSGETTSANRLKLTVCLVVILVTSIANAAIWGAQVDGWIGYAITV 491

Query: 500  PIWLAATVGLRVFVPQARSPKLWGVPLVPWLPSLSIAMNIFLLGSIDGVAFERFSMWTIV 321
            PIW  AT+G+ VFVPQAR+PKLWGVPLVPWLPS S+ +NIFLLGSID  +F RF++WT +
Sbjct: 492  PIWFFATLGISVFVPQARAPKLWGVPLVPWLPSASVFINIFLLGSIDRDSFVRFAIWTGI 551

Query: 320  LLLYYFFVGLHASYDTAKQSLMEKEQNITQLKKAEEG 210
            LL+YYF  GLHASYDTAK+S  E  + +  L+K EEG
Sbjct: 552  LLIYYFLFGLHASYDTAKES--EANRGLEGLQKMEEG 586