BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Cocculus23_contig00019695
         (2079 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2-like [Vitis v...   526   e-146
emb|CBI24922.3| unnamed protein product [Vitis vinifera]              469   e-129
ref|XP_007009328.1| DNA topoisomerase 2 isoform 2 [Theobroma cac...   468   e-129
ref|XP_007009327.1| DNA topoisomerase 2 isoform 1 [Theobroma cac...   466   e-128
gb|EXB68160.1| DNA topoisomerase 2 [Morus notabilis]                  452   e-124
ref|XP_002298421.2| DNA topoisomerase family protein [Populus tr...   448   e-123
ref|XP_002314046.2| DNA topoisomerase family protein [Populus tr...   436   e-119
ref|XP_004229644.1| PREDICTED: DNA topoisomerase 2-like [Solanum...   434   e-119
ref|XP_006345427.1| PREDICTED: DNA topoisomerase 2-like [Solanum...   431   e-118
ref|XP_006482851.1| PREDICTED: DNA topoisomerase 2-like [Citrus ...   422   e-115
ref|XP_006439079.1| hypothetical protein CICLE_v10030505mg [Citr...   422   e-115
ref|XP_002517802.1| DNA topoisomerase II, putative [Ricinus comm...   422   e-115
ref|XP_006439078.1| hypothetical protein CICLE_v10030505mg [Citr...   418   e-114
gb|AAN85207.1| DNA topoisomerase II [Nicotiana tabacum] gi|26984...   410   e-111
gb|EYU27037.1| hypothetical protein MIMGU_mgv1a000169mg [Mimulus...   407   e-110
ref|XP_007220582.1| hypothetical protein PRUPE_ppa000202mg [Prun...   399   e-108
ref|XP_004165384.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...   398   e-108
ref|XP_004149716.1| PREDICTED: DNA topoisomerase 2-like [Cucumis...   398   e-108
ref|XP_006838283.1| hypothetical protein AMTR_s00103p00101630 [A...   389   e-105
ref|XP_007009329.1| Topoisomerase II isoform 3 [Theobroma cacao]...   387   e-105

>ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2-like [Vitis vinifera]
          Length = 1489

 Score =  526 bits (1356), Expect = e-146
 Identities = 301/544 (55%), Positives = 361/544 (66%), Gaps = 1/544 (0%)
 Frame = -3

Query: 2074 KEAGVTYTMSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGTDKLS-PFIKDYREH 1898
            K+  V YT+ GIIEEVNETTLRI+ELPVR+WTQDYKEFLESIMTG DK+  PFIKDY+EH
Sbjct: 889  KQESVGYTVKGIIEEVNETTLRISELPVRKWTQDYKEFLESIMTGNDKIKDPFIKDYKEH 948

Query: 1897 NDDTTVHFEVIMSEENLKMAKQEGLLKKFKLTTTISTSNMHLFDTNGVIKKYDTPEQILE 1718
            NDDTTVHFEVIMSEENL MAKQEGLL+KFKLTT ISTSNMHLFD+NG IKKY+TPEQILE
Sbjct: 949  NDDTTVHFEVIMSEENLLMAKQEGLLQKFKLTTKISTSNMHLFDSNGTIKKYETPEQILE 1008

Query: 1717 EFFHLRLQFYXXXXXXXXXXXXXXXXXXXXXVRFILGVVKGEIIVSNRKRAELFIELHQK 1538
            EFFHLRL+FY                     VRFILGVV+GEIIVSNRKRA+LF ELHQK
Sbjct: 1009 EFFHLRLEFYEKRKRVLLDNLELELLKLENKVRFILGVVRGEIIVSNRKRADLFHELHQK 1068

Query: 1537 GFTPFPXXXXKIEAAVAGATEDADESEESPEVLRNSGVQASDYDYLLSMAIGTLTLEKVQ 1358
            GFTPFP     +E AVAGAT+D +E+EE+ + +   GV+A+DY+YLLSMAIGTLTLEKVQ
Sbjct: 1069 GFTPFPKKSKSVEIAVAGATDDTEEAEENTDAVSKGGVRATDYEYLLSMAIGTLTLEKVQ 1128

Query: 1357 ELCAEKAKLTNEVEELRGASPKSLWMXXXXXXXXXXXXXXKNDAKAEVARKEMKNKVMTE 1178
            ELCA++ KL   V++L+ A+PK+LW+              KNDA+AE  RK++K++VM+E
Sbjct: 1129 ELCADRDKLNKGVDDLKKATPKALWITDLDALERELDEQDKNDARAEETRKQLKSRVMSE 1188

Query: 1177 AGMKASRQVAKNPRKNNTKKANNPQVTVNDTASESVSSTMEVDDVAEAXXXXXXXXXXXX 998
            AGMK SRQ  KNPRKNN KKANN +    +T   S SS ME++ V E             
Sbjct: 1189 AGMKVSRQAPKNPRKNN-KKANNAEPAA-ETMDVSASSAMEMESVPEVVKPKGRAAPRKA 1246

Query: 997  XXXXXKLEKLSLIDNEEDDHEVLSLKQRLAAYNLDSSPAQSESMETEVAKEVPAKKREQS 818
                 ++    L D  EDD EV  LK+RLAAYNL+SSP  S +ME EV +   A+K+E S
Sbjct: 1247 PAKKKEMPTSVLKD--EDDDEVHELKERLAAYNLESSPDGSAAMEAEVPQVPAARKKEPS 1304

Query: 817  KRAAKQKXXXXPTLTEISSDDENSKDDEQMQTIPEEQMSDSDEDFXXXXXXXXXXXXXXX 638
            +RAA QK     + TEIS DDE+ +D E       E++S SD                  
Sbjct: 1305 RRAAAQK-KPLASFTEISDDDEDDEDFE------VEEVSASD----VKKKGGRKPAANAK 1353

Query: 637  XXXXXXXXXXXXXXXXXXXXXXKQLLDQKLITDVLKPAENIGPSPDKKVRKTRASPFNKK 458
                                   QLL Q L+T++ KPAE +G SP+KKVRK RASPFNKK
Sbjct: 1354 AAAAKPAAAAAKNKRGAANKQQPQLLGQTLLTEIFKPAETLGISPEKKVRKMRASPFNKK 1413

Query: 457  SGTV 446
            SG+V
Sbjct: 1414 SGSV 1417


>emb|CBI24922.3| unnamed protein product [Vitis vinifera]
          Length = 1452

 Score =  469 bits (1208), Expect = e-129
 Identities = 283/544 (52%), Positives = 336/544 (61%), Gaps = 1/544 (0%)
 Frame = -3

Query: 2074 KEAGVTYTMSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGTDKLS-PFIKDYREH 1898
            K+  V YT+ GIIEEVNETTLRI+ELPVR+WTQDYKEFLESIMTG DK+  PFIKDY+EH
Sbjct: 889  KQESVGYTVKGIIEEVNETTLRISELPVRKWTQDYKEFLESIMTGNDKIKDPFIKDYKEH 948

Query: 1897 NDDTTVHFEVIMSEENLKMAKQEGLLKKFKLTTTISTSNMHLFDTNGVIKKYDTPEQILE 1718
            NDDTTVHFEVIMSEENL MAKQEGLL+KFKLTT ISTSNMHLFD+NG IKKY+TPEQILE
Sbjct: 949  NDDTTVHFEVIMSEENLLMAKQEGLLQKFKLTTKISTSNMHLFDSNGTIKKYETPEQILE 1008

Query: 1717 EFFHLRLQFYXXXXXXXXXXXXXXXXXXXXXVRFILGVVKGEIIVSNRKRAELFIELHQK 1538
            EFFHLRL+FY                     VRFILGVV+GEIIVSNRKRA+LF ELHQK
Sbjct: 1009 EFFHLRLEFYEKRKRVLLDNLELELLKLENKVRFILGVVRGEIIVSNRKRADLFHELHQK 1068

Query: 1537 GFTPFPXXXXKIEAAVAGATEDADESEESPEVLRNSGVQASDYDYLLSMAIGTLTLEKVQ 1358
                                                 V+A+DY+YLLSMAIGTLTLEKVQ
Sbjct: 1069 -------------------------------------VRATDYEYLLSMAIGTLTLEKVQ 1091

Query: 1357 ELCAEKAKLTNEVEELRGASPKSLWMXXXXXXXXXXXXXXKNDAKAEVARKEMKNKVMTE 1178
            ELCA++ KL   V++L+ A+PK+LW+              KNDA+AE  RK++K++VM+E
Sbjct: 1092 ELCADRDKLNKGVDDLKKATPKALWITDLDALERELDEQDKNDARAEETRKQLKSRVMSE 1151

Query: 1177 AGMKASRQVAKNPRKNNTKKANNPQVTVNDTASESVSSTMEVDDVAEAXXXXXXXXXXXX 998
            AGMK SRQ  KNPRKNN KKANN +    +T   S SS ME++ V E             
Sbjct: 1152 AGMKVSRQAPKNPRKNN-KKANNAEPAA-ETMDVSASSAMEMESVPEVVKPKGRAAPRKA 1209

Query: 997  XXXXXKLEKLSLIDNEEDDHEVLSLKQRLAAYNLDSSPAQSESMETEVAKEVPAKKREQS 818
                 ++    L D  EDD EV  LK+RLAAYNL+SSP  S +ME EV +   A+K+E S
Sbjct: 1210 PAKKKEMPTSVLKD--EDDDEVHELKERLAAYNLESSPDGSAAMEAEVPQVPAARKKEPS 1267

Query: 817  KRAAKQKXXXXPTLTEISSDDENSKDDEQMQTIPEEQMSDSDEDFXXXXXXXXXXXXXXX 638
            +RAA QK     + TEIS DDE+ +D E       E++S SD                  
Sbjct: 1268 RRAAAQK-KPLASFTEISDDDEDDEDFE------VEEVSASD----VKKKGGRKPAANAK 1316

Query: 637  XXXXXXXXXXXXXXXXXXXXXXKQLLDQKLITDVLKPAENIGPSPDKKVRKTRASPFNKK 458
                                   QLL Q L+T++ KPAE +G SP+KKVRK RASPFNKK
Sbjct: 1317 AAAAKPAAAAAKNKRGAANKQQPQLLGQTLLTEIFKPAETLGISPEKKVRKMRASPFNKK 1376

Query: 457  SGTV 446
            SG+V
Sbjct: 1377 SGSV 1380


>ref|XP_007009328.1| DNA topoisomerase 2 isoform 2 [Theobroma cacao]
            gi|508726241|gb|EOY18138.1| DNA topoisomerase 2 isoform 2
            [Theobroma cacao]
          Length = 1285

 Score =  468 bits (1204), Expect = e-129
 Identities = 284/544 (52%), Positives = 348/544 (63%), Gaps = 1/544 (0%)
 Frame = -3

Query: 2074 KEAGVTYTMSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGTDKLSPFIKDYREHN 1895
            KEAGVTYT++GIIEEV+ETTLRITELPVRRWTQDY+EFLESI+TG D   PFIK++R+++
Sbjct: 696  KEAGVTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESIITGND---PFIKEFRQYS 752

Query: 1894 DDTTVHFEVIMSEENLKMAKQEGLLKKFKLTTTISTSNMHLFDTNGVIKKYDTPEQILEE 1715
            DDTTV FEVI++EEN+ +AKQEGLLKKFKLTTTISTSNMHLFD+ G+IKKYDTPEQILEE
Sbjct: 753  DDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTSNMHLFDSKGMIKKYDTPEQILEE 812

Query: 1714 FFHLRLQFYXXXXXXXXXXXXXXXXXXXXXVRFILGVVKGEIIVSNRKRAELFIELHQKG 1535
            FFHLR +FY                     VRFILGVVKGEIIV+NRKRA+LF+EL  KG
Sbjct: 813  FFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRADLFLELQTKG 872

Query: 1534 FTPFPXXXXKIEAAVAGATEDADESEESPEVLRNSGVQASDYDYLLSMAIGTLTLEKVQE 1355
            FTPFP     +E AVAGAT+D +E+EE+ EV    G+QASDYDYLLSMAIG+LTLEKVQE
Sbjct: 873  FTPFPKKAKTVEVAVAGATDDTEETEENSEV-SAKGLQASDYDYLLSMAIGSLTLEKVQE 931

Query: 1354 LCAEKAKLTNEVEELRGASPKSLWMXXXXXXXXXXXXXXKNDAKAEVARKEMKNKVMTEA 1175
            LCA++ KL  EVE+LR A+PKSLW+                 A+AE A K +K +   EA
Sbjct: 932  LCADRDKLQQEVEDLRKATPKSLWL-KDLDNLEIQLDEQDKAAQAEEAAKLVKGR--GEA 988

Query: 1174 GMKASRQVAKNPRKNNTKKANNPQVTVNDTASESVSSTMEVDDVAEAXXXXXXXXXXXXX 995
            G +A RQ  K PRK N K+ N    TV +T   S SS ME  + A A             
Sbjct: 989  GKRAQRQAPKIPRKINKKEKN--AETVTETTDISSSSAMETAETAPA------AVKPKGR 1040

Query: 994  XXXXKLEKLSLIDNEEDDHEVLSLKQRLAAYNLDSSPAQSESMETEVAKEVPAKKREQSK 815
                K +K    D++++D  +  L++RLA YNLDSSP  S +METEV  +VPA K+E SK
Sbjct: 1041 GGSRKAKKDDSDDDDDEDFGIPDLRERLAKYNLDSSPDHSAAMETEV-PQVPAGKKEPSK 1099

Query: 814  RAAKQKXXXXPTLTEIS-SDDENSKDDEQMQTIPEEQMSDSDEDFXXXXXXXXXXXXXXX 638
            RAA  +     +L+EIS S  E   +DE ++ +         E                 
Sbjct: 1100 RAAAARKKPATSLSEISESIGEIDINDEDLEVV---------EVAAAAAPAGKKGGRKPA 1150

Query: 637  XXXXXXXXXXXXXXXXXXXXXXKQLLDQKLITDVLKPAENIGPSPDKKVRKTRASPFNKK 458
                                  K+   QKL+T++LKPAE+ G SP+KKVRK RASPFNKK
Sbjct: 1151 ANSKAAAKPPAAAKKRGPAAAGKKSQQQKLLTEMLKPAEDSGISPEKKVRKMRASPFNKK 1210

Query: 457  SGTV 446
            SG+V
Sbjct: 1211 SGSV 1214


>ref|XP_007009327.1| DNA topoisomerase 2 isoform 1 [Theobroma cacao]
            gi|508726240|gb|EOY18137.1| DNA topoisomerase 2 isoform 1
            [Theobroma cacao]
          Length = 1473

 Score =  466 bits (1200), Expect = e-128
 Identities = 283/544 (52%), Positives = 347/544 (63%), Gaps = 1/544 (0%)
 Frame = -3

Query: 2074 KEAGVTYTMSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGTDKLSPFIKDYREHN 1895
            KEAGVTYT++GIIEEV+ETTLRITELPVRRWTQDY+EFLESI+TG D   PFIK++R+++
Sbjct: 885  KEAGVTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESIITGND---PFIKEFRQYS 941

Query: 1894 DDTTVHFEVIMSEENLKMAKQEGLLKKFKLTTTISTSNMHLFDTNGVIKKYDTPEQILEE 1715
            DDTTV FEVI++EEN+ +AKQEGLLKKFKLTTTISTSNMHLFD+ G+IKKYDTPEQILEE
Sbjct: 942  DDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTSNMHLFDSKGMIKKYDTPEQILEE 1001

Query: 1714 FFHLRLQFYXXXXXXXXXXXXXXXXXXXXXVRFILGVVKGEIIVSNRKRAELFIELHQKG 1535
            FFHLR +FY                     VRFILGVVKGEIIV+NRKRA+LF+EL  KG
Sbjct: 1002 FFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRADLFLELQTKG 1061

Query: 1534 FTPFPXXXXKIEAAVAGATEDADESEESPEVLRNSGVQASDYDYLLSMAIGTLTLEKVQE 1355
            FTPFP     +E AVAGAT+D +E+EE+ EV    G+QASDYDYLLSMAIG+LTLEKVQE
Sbjct: 1062 FTPFPKKAKTVEVAVAGATDDTEETEENSEV-SAKGLQASDYDYLLSMAIGSLTLEKVQE 1120

Query: 1354 LCAEKAKLTNEVEELRGASPKSLWMXXXXXXXXXXXXXXKNDAKAEVARKEMKNKVMTEA 1175
            LCA++ KL  EVE+LR A+PKSLW+                 A+AE A K +K +   EA
Sbjct: 1121 LCADRDKLQQEVEDLRKATPKSLWL-KDLDNLEIQLDEQDKAAQAEEAAKLVKGR--GEA 1177

Query: 1174 GMKASRQVAKNPRKNNTKKANNPQVTVNDTASESVSSTMEVDDVAEAXXXXXXXXXXXXX 995
            G +A RQ  K PRK N K+ N    TV +T   S SS ME +    A             
Sbjct: 1178 GKRAQRQAPKIPRKINKKEKN--AETVTETTDISSSSAMETETAPAA-------VKPKGR 1228

Query: 994  XXXXKLEKLSLIDNEEDDHEVLSLKQRLAAYNLDSSPAQSESMETEVAKEVPAKKREQSK 815
                K +K    D++++D  +  L++RLA YNLDSSP  S +METEV  +VPA K+E SK
Sbjct: 1229 GGSRKAKKDDSDDDDDEDFGIPDLRERLAKYNLDSSPDHSAAMETEV-PQVPAGKKEPSK 1287

Query: 814  RAAKQKXXXXPTLTEIS-SDDENSKDDEQMQTIPEEQMSDSDEDFXXXXXXXXXXXXXXX 638
            RAA  +     +L+EIS S  E   +DE ++ +         E                 
Sbjct: 1288 RAAAARKKPATSLSEISESIGEIDINDEDLEVV---------EVAAAAAPAGKKGGRKPA 1338

Query: 637  XXXXXXXXXXXXXXXXXXXXXXKQLLDQKLITDVLKPAENIGPSPDKKVRKTRASPFNKK 458
                                  K+   QKL+T++LKPAE+ G SP+KKVRK RASPFNKK
Sbjct: 1339 ANSKAAAKPPAAAKKRGPAAAGKKSQQQKLLTEMLKPAEDSGISPEKKVRKMRASPFNKK 1398

Query: 457  SGTV 446
            SG+V
Sbjct: 1399 SGSV 1402


>gb|EXB68160.1| DNA topoisomerase 2 [Morus notabilis]
          Length = 1451

 Score =  452 bits (1162), Expect = e-124
 Identities = 273/552 (49%), Positives = 338/552 (61%), Gaps = 9/552 (1%)
 Frame = -3

Query: 2074 KEAGVTYTMSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGTDKLS-PFIKDYREH 1898
            KEA  ++ +SG++EEVNETT+RITELP+RRWTQDYKEFL+SI  G DK   PFI+D+ +H
Sbjct: 852  KEA--SFFVSGLMEEVNETTVRITELPIRRWTQDYKEFLDSICYGNDKAKDPFIEDFTQH 909

Query: 1897 NDDTTVHFEVIMSEENLKMAKQEGLLKKFKLTTTISTSNMHLFDTNGVIKKYDTPEQILE 1718
            +D +TV   V ++EE L   KQEGLLKK KLTT+IST+NMHLFD NGVIKKYDTPEQILE
Sbjct: 910  SDHSTVDILVHLAEETLIAVKQEGLLKKLKLTTSISTANMHLFDANGVIKKYDTPEQILE 969

Query: 1717 EFFHLRLQFYXXXXXXXXXXXXXXXXXXXXXVRFILGVVKGEIIVSNRKRAELFIELHQK 1538
            EF+HLRL+FY                     VRFILGVV GEI+VSNRKRA+LF+EL +K
Sbjct: 970  EFYHLRLEFYEKRKKALLDNLELELLKLANKVRFILGVVTGEIVVSNRKRADLFVELQRK 1029

Query: 1537 GFTPFPXXXXKIEAAVAGATEDADESEESPEV-LRNSGVQASDYDYLLSMAIGTLTLEKV 1361
            GFTPFP     +E  VAG TEDA+++EE+      ++  + SDY+YLLSMAIGTLTLEKV
Sbjct: 1030 GFTPFPKKTKAVEPEVAGVTEDAEDTEENSNAEAISTEARISDYEYLLSMAIGTLTLEKV 1089

Query: 1360 QELCAEKAKLTNEVEELRGASPKSLWMXXXXXXXXXXXXXXKNDAKAEVARKEMKNKVMT 1181
            Q LC EK KL NEVEELR A+PKSLW+              K+DA+AE ARK+ K +V  
Sbjct: 1090 QALCGEKDKLNNEVEELRKATPKSLWVKDLDALETQLDELNKSDAQAEEARKKSKGQVKN 1149

Query: 1180 EAGMKASRQVAKNPRKNNTKKANNPQVTVNDTASESVSSTMEVDDVAEAXXXXXXXXXXX 1001
             A  K SRQ  K PRK NTKKA+N +   + T  E+  S ME +   E            
Sbjct: 1150 AAVSKVSRQAPKVPRK-NTKKASNAEAIADIT--ENFDSAMEFEKAPEV------AKPKG 1200

Query: 1000 XXXXXXKLEKLSLIDNEEDDHEVLSLKQRLAAYNLDSSPAQSESMETEVAKEVPAKKREQ 821
                     K+ + D+++DD EVL+LK RLAAYNLDSSP +S  M+TE A +VP  K+  
Sbjct: 1201 RAGPKKAASKVVVEDDDDDDDEVLALKDRLAAYNLDSSPDKSSEMDTE-APQVPVPKKAP 1259

Query: 820  SKRAAKQKXXXXPTLTEISSDDENSKDDEQMQTIPEEQMSDSDEDF-------XXXXXXX 662
            +KRAA QK         ++ DD+   DD+++         D DEDF              
Sbjct: 1260 TKRAAAQKKTLATVSETVNLDDD---DDDEI---------DGDEDFELESTAPAKAAAKK 1307

Query: 661  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKQLLDQKLITDVLKPAENIGPSPDKKVRKT 482
                                           Q+L QKL+TD+LKPAEN G SP+KKVRK 
Sbjct: 1308 GGKKPAVSTKAVSKAPAAAATKRRGAANKEPQVLGQKLLTDMLKPAENSGLSPEKKVRKM 1367

Query: 481  RASPFNKKSGTV 446
            RASPFNKKSG+V
Sbjct: 1368 RASPFNKKSGSV 1379


>ref|XP_002298421.2| DNA topoisomerase family protein [Populus trichocarpa]
            gi|550348289|gb|EEE83226.2| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 1485

 Score =  448 bits (1152), Expect = e-123
 Identities = 275/551 (49%), Positives = 341/551 (61%), Gaps = 8/551 (1%)
 Frame = -3

Query: 2074 KEAGVTYTMSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGTDKLS------PFIK 1913
            KEAG +YT++G+I EVNETTLRITELP+RRWT DYK FL S+  G    +      PFIK
Sbjct: 902  KEAGCSYTVNGVINEVNETTLRITELPIRRWTDDYKAFLNSVTEGNRDENGNLPKDPFIK 961

Query: 1912 DYREHNDDTTVHFEVIMSEENLKMAKQEGLLKKFKLTTTISTSNMHLFDTNGVIKKYDTP 1733
            D+R++ DD TV FEV++SEEN+ +AKQEGLLKKFKLTTTISTSNMHLFD+ GVIKKYD P
Sbjct: 962  DFRKYGDDATVVFEVLLSEENMMIAKQEGLLKKFKLTTTISTSNMHLFDSAGVIKKYDNP 1021

Query: 1732 EQILEEFFHLRLQFYXXXXXXXXXXXXXXXXXXXXXVRFILGVVKGEIIVSNRKRAELFI 1553
            EQILEEFFHLRL++Y                     VRFILGVV+GEIIV+NRKRA+LF+
Sbjct: 1022 EQILEEFFHLRLEYYERRKKVLLENLEFELLKLENKVRFILGVVRGEIIVNNRKRADLFL 1081

Query: 1552 ELHQKGFTPFPXXXXKIEAAVAGATEDADESEESPEVLRNSGVQASDYDYLLSMAIGTLT 1373
            ELHQKGFTP P      +A VAGAT+D DE+E+S EV   SGV+ASDYDYLLSMAIGTLT
Sbjct: 1082 ELHQKGFTPIPKKS---KAVVAGATDDKDEAEDSLEV---SGVRASDYDYLLSMAIGTLT 1135

Query: 1372 LEKVQELCAEKAKLTNEVEELRGASPKSLWMXXXXXXXXXXXXXXKNDAKAEVARKEMKN 1193
            LEKVQ+LCA+  KL  EV+ LR  +P  LW+              K DA+AE ARK++K 
Sbjct: 1136 LEKVQQLCADHDKLNGEVDNLRKTTPIVLWVKDLEALEMQLDVLDKYDAEAEEARKKLKG 1195

Query: 1192 KVMTEAGMKASRQVAKNPRKNNTKKANNPQVTVNDTASESVSSTMEVDDVAEAXXXXXXX 1013
                EAG K S+Q  KNPRK  TKKA N +V+V +T  ++ SS ME ++ AE        
Sbjct: 1196 DANGEAGFKVSKQAPKNPRK-YTKKAINEEVSV-ETMGKASSSAMETENAAEVVKPKGRA 1253

Query: 1012 XXXXXXXXXXKLEKLSLIDNEEDDHEVLSLKQRLAAYNLDSSPAQSESMETEVAKEVPAK 833
                        EK S I +E+D  E+ SLK RL AY LDSSP QS  METEV + VPA 
Sbjct: 1254 GSRKAPAKKQ--EKPSPISDEDD--EIESLKDRLKAYRLDSSPEQSADMETEVLR-VPA- 1307

Query: 832  KREQSKRAAKQKXXXXPTLTEISSDDENSKD--DEQMQTIPEEQMSDSDEDFXXXXXXXX 659
                 ++AA++K     ++   S D+ +  D  D Q++ +PE +     +          
Sbjct: 1308 ----GRKAARKKPLAAVSVISDSEDEPDLDDDFDVQVKAVPETKKKGGRK---------- 1353

Query: 658  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXKQLLDQKLITDVLKPAENIGPSPDKKVRKTR 479
                                          Q L Q+L+T++LKPAE  G SP+KKVRK R
Sbjct: 1354 -----AAAANDKAAKPPAATKRRGPASKQSQGLGQQLLTEMLKPAEESGISPEKKVRKMR 1408

Query: 478  ASPFNKKSGTV 446
            ASPFNKKSG++
Sbjct: 1409 ASPFNKKSGSL 1419


>ref|XP_002314046.2| DNA topoisomerase family protein [Populus trichocarpa]
            gi|550331162|gb|EEE88001.2| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 1482

 Score =  436 bits (1121), Expect = e-119
 Identities = 267/554 (48%), Positives = 339/554 (61%), Gaps = 11/554 (1%)
 Frame = -3

Query: 2074 KEAGVT-YTMSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGTDKLS------PFI 1916
            KE G + YT++G+I EVNETTLRITELP+RRWT DYK FL S+  GT   +      PF+
Sbjct: 888  KEGGCSSYTVNGVINEVNETTLRITELPIRRWTDDYKAFLNSVTEGTRDENGNLPKDPFV 947

Query: 1915 KDYREHNDDTTVHFEVIMSEENLKMAKQEGLLKKFKLTTTISTSNMHLFDTNGVIKKYDT 1736
            KD+R++ DD  VHFEV +SEEN+ +AKQEGLLKKFKLTTTISTSNMHLFD+ GVIKKYD 
Sbjct: 948  KDFRKYGDDAAVHFEVQLSEENMLVAKQEGLLKKFKLTTTISTSNMHLFDSAGVIKKYDN 1007

Query: 1735 PEQILEEFFHLRLQFYXXXXXXXXXXXXXXXXXXXXXVRFILGVVKGEIIVSNRKRAELF 1556
            PEQILE FFHLRL++Y                     VRFILGVV+GEIIV+NRKRA+L 
Sbjct: 1008 PEQILENFFHLRLEYYETRKKVLLENLEFELLKLENKVRFILGVVRGEIIVNNRKRADLL 1067

Query: 1555 IELHQKGFTPFPXXXXKIEAAVAGATEDADESEESPEVLRNSGVQASDYDYLLSMAIGTL 1376
            +ELHQKGF   P      +A VAGAT+D +E+E+SP+V   SGV+ASDYDYLLSMAIGTL
Sbjct: 1068 LELHQKGFNAIPKKS---KAVVAGATDDTEEAEDSPDV---SGVRASDYDYLLSMAIGTL 1121

Query: 1375 TLEKVQELCAEKAKLTNEVEELRGASPKSLWMXXXXXXXXXXXXXXKNDAKAEVARKEMK 1196
            TLE+VQ+LCA++ KL  EV+ LR  +PK LW+              + DA+AE AR+++K
Sbjct: 1122 TLERVQQLCADRDKLNGEVDSLRKTTPKVLWVKDLEALEMQLDMLDEYDAEAEEARRKLK 1181

Query: 1195 -NKVMTEAGMKASRQVAKNPRKNNTKKANNPQVTVNDTASESVSSTMEVDDVAEAXXXXX 1019
                  EAG K S+Q  K PRK NTKKA N +V+V  T + S S  +E      A     
Sbjct: 1182 GGGAKGEAGFKVSKQAPKYPRK-NTKKAINEEVSVETTGTSS-SFAIETASSENAAAVVK 1239

Query: 1018 XXXXXXXXXXXXKLEKLS-LIDNEEDDHEVLSLKQRLAAYNLDSSPAQSESMETEVAKEV 842
                        K+EKLS ++D+ ++D E+ SLK RL AY LDSSP QS  MET+V  +V
Sbjct: 1240 PKGRAGSKKAPAKMEKLSPVLDDFDEDDEIESLKDRLNAYRLDSSPEQSADMETDVL-QV 1298

Query: 841  PAKKREQSKRAAKQKXXXXPTLTEISSDDENSKDDE--QMQTIPEEQMSDSDEDFXXXXX 668
            PA+     + AA++K     ++   S D+ N  DD   +++ +PE +     +       
Sbjct: 1299 PAR-----RGAARKKPLANVSVISDSEDEPNLDDDADVEVKALPETKKKGGRK------- 1346

Query: 667  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKQLLDQKLITDVLKPAENIGPSPDKKVR 488
                                             Q L QKL+T++LKPAE  G SP+KKVR
Sbjct: 1347 --------AAAANDKAAKPPAATKRRGPASQQSQGLGQKLLTEMLKPAEGAGISPEKKVR 1398

Query: 487  KTRASPFNKKSGTV 446
            K RASPFNKKSG+V
Sbjct: 1399 KVRASPFNKKSGSV 1412


>ref|XP_004229644.1| PREDICTED: DNA topoisomerase 2-like [Solanum lycopersicum]
          Length = 1477

 Score =  434 bits (1116), Expect = e-119
 Identities = 263/544 (48%), Positives = 329/544 (60%), Gaps = 1/544 (0%)
 Frame = -3

Query: 2074 KEAGVTYTMSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGTDKLSP-FIKDYREH 1898
            KE G TYT++GIIEEV+ETTLRI+ELPVRRWT+DYK+FLES+   TDK    FIK+ R +
Sbjct: 885  KETGATYTVTGIIEEVSETTLRISELPVRRWTEDYKQFLESMTVSTDKAKDSFIKEVRAY 944

Query: 1897 NDDTTVHFEVIMSEENLKMAKQEGLLKKFKLTTTISTSNMHLFDTNGVIKKYDTPEQILE 1718
             D+ +V FEVIMSE+NL +A+QEGLLKKFKLTTTISTSNMHLFD+ G IKKYD PE+ILE
Sbjct: 945  GDENSVCFEVIMSEDNLLLAQQEGLLKKFKLTTTISTSNMHLFDSKGKIKKYDAPEEILE 1004

Query: 1717 EFFHLRLQFYXXXXXXXXXXXXXXXXXXXXXVRFILGVVKGEIIVSNRKRAELFIELHQK 1538
            EF+H+RL++Y                     V+FILGVVKGEIIV+NRKRAEL +EL  K
Sbjct: 1005 EFYHVRLEYYEKRKKALLEILELELLRIENKVKFILGVVKGEIIVNNRKRAELLLELKNK 1064

Query: 1537 GFTPFPXXXXKIEAAVAGATEDADESEESPEVLRNSGVQASDYDYLLSMAIGTLTLEKVQ 1358
            GFTPFP     +EA VA +T+DAD+SEESPE   + GV+ASDYDYLLSMAIGTLTLEKVQ
Sbjct: 1065 GFTPFP-KKKPVEAVVADSTDDADDSEESPEE-SSRGVRASDYDYLLSMAIGTLTLEKVQ 1122

Query: 1357 ELCAEKAKLTNEVEELRGASPKSLWMXXXXXXXXXXXXXXKNDAKAEVARKEMKNKVMTE 1178
            ELCA++ KL  EVE++R A+PK LWM              K D + E AR+++K KVM  
Sbjct: 1123 ELCADRDKLNAEVEDMRNATPKHLWMKDLDVLDKQLDEQDKIDIQTEEAREKLKKKVMNA 1182

Query: 1177 AGMKASRQVAKNPRKNNTKKANNPQVTVNDTASESVSSTMEVDDVAEAXXXXXXXXXXXX 998
            AG  A +     PRK N K             +ES + +M+V   + A            
Sbjct: 1183 AGKAAPK---PKPRKTNKK-------------AESTAESMDVSFGSTAETANVSEVVKPK 1226

Query: 997  XXXXXKLEKLSLIDNEEDDHEVLSLKQRLAAYNLDSSPAQSESMETEVAKEVPAKKREQS 818
                    K  ++++EE++ EVL+LK RLAAYNL+SSP +SE  ETEV K   A+ +  +
Sbjct: 1227 GRGRPAKAKPIVVEDEEEEDEVLALKDRLAAYNLNSSPDRSEVTETEVPK---AQTKAPA 1283

Query: 817  KRAAKQKXXXXPTLTEISSDDENSKDDEQMQTIPEEQMSDSDEDFXXXXXXXXXXXXXXX 638
            KRAA QK     T  ++S                E+ +   D++F               
Sbjct: 1284 KRAAAQKKALPST-PDVSDG--------------EDAIEIDDDEFEPAAAVGGKKKGGRK 1328

Query: 637  XXXXXXXXXXXXXXXXXXXXXXKQLLDQKLITDVLKPAENIGPSPDKKVRKTRASPFNKK 458
                                   Q + Q+LIT VLKPAE+ G SPD+KVRK RASPFNKK
Sbjct: 1329 PAAAKAAAAPKPPGKKAPANNQSQSVGQRLITQVLKPAEDAGVSPDRKVRKMRASPFNKK 1388

Query: 457  SGTV 446
            SG V
Sbjct: 1389 SGAV 1392


>ref|XP_006345427.1| PREDICTED: DNA topoisomerase 2-like [Solanum tuberosum]
          Length = 1485

 Score =  431 bits (1107), Expect = e-118
 Identities = 267/546 (48%), Positives = 329/546 (60%), Gaps = 3/546 (0%)
 Frame = -3

Query: 2074 KEAGVTYTMSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGTDKLSP-FIKDYREH 1898
            KE G TYT++GIIEE +ETTLRI+ELPVRRWT+DYK+FLES+   TDK    FIK+ R +
Sbjct: 885  KETGATYTVTGIIEEFSETTLRISELPVRRWTEDYKQFLESMTVSTDKSKDAFIKEVRAY 944

Query: 1897 NDDTTVHFEVIMSEENLKMAKQEGLLKKFKLTTTISTSNMHLFDTNGVIKKYDTPEQILE 1718
             D+ +V FEVIMSEENL +A+QEGLLKKFKLTTTISTSNMHLFD+ G IKKYD PE+ILE
Sbjct: 945  GDENSVCFEVIMSEENLLLAQQEGLLKKFKLTTTISTSNMHLFDSKGKIKKYDAPEEILE 1004

Query: 1717 EFFHLRLQFYXXXXXXXXXXXXXXXXXXXXXVRFILGVVKGEIIVSNRKRAELFIELHQK 1538
            EF+H+RL++Y                     VRFILGVVKGEIIV+NRKRA+L +EL  K
Sbjct: 1005 EFYHVRLEYYEKRKKTLLEILELELLRIENKVRFILGVVKGEIIVNNRKRADLLLELKNK 1064

Query: 1537 GFTPFPXXXXKIEAAVAGATEDADESEESPEVLRNSGVQASDYDYLLSMAIGTLTLEKVQ 1358
            GFTPFP     +EA VA +T+DA++SEESPE   N GV+ASDYDYLLSMAIGTLTLEKVQ
Sbjct: 1065 GFTPFP-KKKPVEAVVADSTDDAEDSEESPEE-SNKGVRASDYDYLLSMAIGTLTLEKVQ 1122

Query: 1357 ELCAEKAKLTNEVEELRGASPKSLWMXXXXXXXXXXXXXXKNDAKAEVARKEMKNKVMTE 1178
            ELCA++ KL  EVE++R A+PK LWM              K D + E AR+++K KVM  
Sbjct: 1123 ELCADRDKLNAEVEDMRNATPKDLWMKDLDVLDKQLDEQDKLDIQTEEAREKLKKKVMNA 1182

Query: 1177 AGMKASRQVAKNPRKNNTKKANNPQVTVN--DTASESVSSTMEVDDVAEAXXXXXXXXXX 1004
            AG KA +     PRK  TKKA   + T    D +  S++ T  V +VA+           
Sbjct: 1183 AG-KAPK---PKPRK-TTKKAAVVESTAEPMDVSVGSMAETANVTEVAKPKGRGGGSKKA 1237

Query: 1003 XXXXXXXKLEKLSLIDNEEDDHEVLSLKQRLAAYNLDSSPAQSESMETEVAKEVPAKKRE 824
                      K  ++++EE++ EVL+LK RLAAYNL+SSP +SE  ETE  K   A+ + 
Sbjct: 1238 PAK------AKPVVVEDEEEEDEVLALKDRLAAYNLNSSPDRSEVTETEAPK---AQTKA 1288

Query: 823  QSKRAAKQKXXXXPTLTEISSDDENSKDDEQMQTIPEEQMSDSDEDFXXXXXXXXXXXXX 644
             +KRAA QK     T      +DE    D              D +F             
Sbjct: 1289 PAKRAAAQKKALPSTPDVSEGEDEIEISD--------------DNEFAPEVAVGGKKKGG 1334

Query: 643  XXXXXXXXXXXXXXXXXXXXXXXXKQLLDQKLITDVLKPAENIGPSPDKKVRKTRASPFN 464
                                     Q + Q+LIT VLKPAE+ G SPD+KVRK R SPFN
Sbjct: 1335 RKPAAAKAAAAPKPPKKRAPANKQSQSVGQRLITQVLKPAEDAGVSPDRKVRKMRESPFN 1394

Query: 463  KKSGTV 446
            KKSG V
Sbjct: 1395 KKSGAV 1400


>ref|XP_006482851.1| PREDICTED: DNA topoisomerase 2-like [Citrus sinensis]
          Length = 1456

 Score =  422 bits (1086), Expect = e-115
 Identities = 267/551 (48%), Positives = 336/551 (60%), Gaps = 8/551 (1%)
 Frame = -3

Query: 2074 KEAGVTYTMSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGTDKLSPFIKDYREHN 1895
            KEAGVTYT++GIIEEVNETTLRI ELP+RRWTQDY+EFLESI+   D    FI+ +R+++
Sbjct: 884  KEAGVTYTVTGIIEEVNETTLRIKELPIRRWTQDYREFLESIIDQNDS---FIRGFRQYS 940

Query: 1894 DDTTVHFEVIMSEENLKMAKQEGLLKKFKLTTTISTSNMHLFDTNGVIKKYDTPEQILEE 1715
            DDTTV FEV +SEE++   KQEGLLKKFKLTTTISTSNMHLFD+ GVIKKYDTPEQILEE
Sbjct: 941  DDTTVDFEVFLSEESMMRTKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEQILEE 1000

Query: 1714 FFHLRLQFYXXXXXXXXXXXXXXXXXXXXXVRFILGVVKGEIIVSNRKRAELFIELHQKG 1535
            FFH+RL+FY                     VRFILGVV GEI+V+NRKR +L +EL QKG
Sbjct: 1001 FFHIRLEFYEKRKKVQLENLELELLKLENKVRFILGVVNGEIVVNNRKRTDLLLELRQKG 1060

Query: 1534 FTPFPXXXXKIEAAVAGATEDADESEESPEVLRNSGVQASDYDYLLSMAIGTLTLEKVQE 1355
            FTPFP     IEA VAGAT++ +ESEE+PEV+  +GVQ+ DYDYLLSMAIGTLTLEKVQ 
Sbjct: 1061 FTPFPKNSKSIEAVVAGATDETEESEENPEVV--NGVQSIDYDYLLSMAIGTLTLEKVQG 1118

Query: 1354 LCAEKAKLTNEVEELRGASPKSLWMXXXXXXXXXXXXXXKNDAKAEVARKEMKNKVMTEA 1175
            L A++ KL  EV++LR A+P+SLW+              K+DA+AE  R ++K    ++A
Sbjct: 1119 LLADRDKLNEEVDDLRKATPESLWVKDLDALDMQLDELDKSDARAEEERMKIKGNGNSDA 1178

Query: 1174 GMK-ASRQVAKNPRKNNTKKANNPQVTVNDTASESVSSTMEVDDVAEAXXXXXXXXXXXX 998
            G K  +++  KN RKN+ KK+NN + T          +  E+D+V +             
Sbjct: 1179 GPKIVAKRAPKNARKND-KKSNNARAT---------EAMGEMDNVTKV-----VKPKGRA 1223

Query: 997  XXXXXKLEKLSLIDNEEDDHEVLSLKQRLAAYN-------LDSSPAQSESMETEVAKEVP 839
                   EKL   D+EE+D EV  LKQRLA  N       L+ SP QS  METE   +VP
Sbjct: 1224 GLKKAPAEKL---DDEEED-EVPDLKQRLAKLNEQLASTKLEPSPDQSGVMETEKV-QVP 1278

Query: 838  AKKREQSKRAAKQKXXXXPTLTEISSDDENSKDDEQMQTIPEEQMSDSDEDFXXXXXXXX 659
            AKK+E SKR A QK     T+    S+DE   DD++   I   +                
Sbjct: 1279 AKKKEPSKRTAAQK--KAVTVETSDSEDEIIIDDDEAFEIAAPEAGKK------------ 1324

Query: 658  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXKQLLDQKLITDVLKPAENIGPSPDKKVRKTR 479
                                         +  L Q+L+T++LKP E+   SP+KKVRK R
Sbjct: 1325 GGRKAAGNTKAAKPAAETKKRGPAKKQQPEASLGQRLLTEMLKPTES---SPEKKVRKMR 1381

Query: 478  ASPFNKKSGTV 446
            ASPFNKKSG++
Sbjct: 1382 ASPFNKKSGSM 1392


>ref|XP_006439079.1| hypothetical protein CICLE_v10030505mg [Citrus clementina]
            gi|557541275|gb|ESR52319.1| hypothetical protein
            CICLE_v10030505mg [Citrus clementina]
          Length = 1456

 Score =  422 bits (1086), Expect = e-115
 Identities = 267/551 (48%), Positives = 336/551 (60%), Gaps = 8/551 (1%)
 Frame = -3

Query: 2074 KEAGVTYTMSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGTDKLSPFIKDYREHN 1895
            KEAGVTYT++GIIEEVNETTLRI ELP+RRWTQDY+EFLESI+   D    FI+ +R+++
Sbjct: 884  KEAGVTYTVTGIIEEVNETTLRIKELPIRRWTQDYREFLESIIDQNDS---FIRGFRQYS 940

Query: 1894 DDTTVHFEVIMSEENLKMAKQEGLLKKFKLTTTISTSNMHLFDTNGVIKKYDTPEQILEE 1715
            DDTTV FEV +SEE++   KQEGLLKKFKLTTTISTSNMHLFD+ GVIKKYDTPEQILEE
Sbjct: 941  DDTTVDFEVFLSEESMMRTKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEQILEE 1000

Query: 1714 FFHLRLQFYXXXXXXXXXXXXXXXXXXXXXVRFILGVVKGEIIVSNRKRAELFIELHQKG 1535
            FFH+RL+FY                     VRFILGVV GEI+V+NRKR +L +EL QKG
Sbjct: 1001 FFHIRLEFYEKRKKVQLENLELELLKLENKVRFILGVVNGEIVVNNRKRTDLLLELRQKG 1060

Query: 1534 FTPFPXXXXKIEAAVAGATEDADESEESPEVLRNSGVQASDYDYLLSMAIGTLTLEKVQE 1355
            FTPFP     IEA VAGAT++ +ESEE+PEV+  +GVQ+ DYDYLLSMAIGTLTLEKVQ 
Sbjct: 1061 FTPFPKNSKSIEAVVAGATDETEESEENPEVV--NGVQSIDYDYLLSMAIGTLTLEKVQG 1118

Query: 1354 LCAEKAKLTNEVEELRGASPKSLWMXXXXXXXXXXXXXXKNDAKAEVARKEMKNKVMTEA 1175
            L A++ KL  EV++LR A+P+SLW+              K+DA+AE  R ++K    ++A
Sbjct: 1119 LLADRDKLNEEVDDLRKATPESLWVKDLDALDMQLDELDKSDARAEEERMKIKGNGNSDA 1178

Query: 1174 GMK-ASRQVAKNPRKNNTKKANNPQVTVNDTASESVSSTMEVDDVAEAXXXXXXXXXXXX 998
            G K  +++  KN RKN+ KK+NN + T          +  E+D+V +             
Sbjct: 1179 GPKIVAKRAPKNARKND-KKSNNARAT---------EAMGEMDNVTKV-----VKPKGRA 1223

Query: 997  XXXXXKLEKLSLIDNEEDDHEVLSLKQRLAAYN-------LDSSPAQSESMETEVAKEVP 839
                   EKL   D+EE+D EV  LKQRLA  N       L+ SP QS  METE   +VP
Sbjct: 1224 GLKKAPAEKL---DDEEED-EVPDLKQRLAKLNEQLASTKLEPSPDQSGVMETEKV-QVP 1278

Query: 838  AKKREQSKRAAKQKXXXXPTLTEISSDDENSKDDEQMQTIPEEQMSDSDEDFXXXXXXXX 659
            AKK+E SKR A QK     T+    S+DE   DD++   I   +                
Sbjct: 1279 AKKKEPSKRTAAQK--KAVTVETSDSEDEIIIDDDEAFEIAAPEAGKK------------ 1324

Query: 658  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXKQLLDQKLITDVLKPAENIGPSPDKKVRKTR 479
                                         +  L Q+L+T++LKP E+   SP+KKVRK R
Sbjct: 1325 GGRKAAGNTKAAKPAVETKKRGPAKKQQPEASLGQRLLTEMLKPTES---SPEKKVRKMR 1381

Query: 478  ASPFNKKSGTV 446
            ASPFNKKSG++
Sbjct: 1382 ASPFNKKSGSM 1392


>ref|XP_002517802.1| DNA topoisomerase II, putative [Ricinus communis]
            gi|223543074|gb|EEF44609.1| DNA topoisomerase II,
            putative [Ricinus communis]
          Length = 1212

 Score =  422 bits (1084), Expect = e-115
 Identities = 264/555 (47%), Positives = 334/555 (60%), Gaps = 12/555 (2%)
 Frame = -3

Query: 2074 KEAGVTYTMSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMT------GTDKLSPFIK 1913
            KE G +Y ++GIIEEVNETT+RITELP+RRWT +YK+FL S++       G      FIK
Sbjct: 603  KEGGGSYAVNGIIEEVNETTVRITELPIRRWTDEYKDFLNSVIENVRDEKGNLPKDAFIK 662

Query: 1912 DYREHNDDTTVHFEVIMSEENLKMAKQEGLLKKFKLTTTISTSNMHLFDTNGVIKKYDTP 1733
            D+R++ DD +V FEV++SEE +K  K EGLLKKFKL TTISTSNMHLFD  GVIKKYD+P
Sbjct: 663  DFRKYGDDVSVCFEVLLSEEKMKQVKDEGLLKKFKLATTISTSNMHLFDPKGVIKKYDSP 722

Query: 1732 EQILEEFFHLRLQFYXXXXXXXXXXXXXXXXXXXXXVRFILGVVKGEIIVSNRKRAELFI 1553
            E+ILEEF HLR + Y                     VRFILGVV GEIIV+NRKRAEL +
Sbjct: 723  EEILEEFVHLRFELYEKRKNFKLASLEMEALILENKVRFILGVVTGEIIVNNRKRAELLL 782

Query: 1552 ELHQKGFTPFPXXXXKIEAAVAGATEDADESEESPEVLRNS--GVQASDYDYLLSMAIGT 1379
            EL QKGFTPFP     +EA VAGA +D +ESE + +V  NS  GVQA+DY+YLLSM+IGT
Sbjct: 783  ELRQKGFTPFP-KNKPVEAVVAGAADDTEESESTEDVEENSKTGVQATDYEYLLSMSIGT 841

Query: 1378 LTLEKVQELCAEKAKLTNEVEELRGASPKSLWMXXXXXXXXXXXXXXKNDAKAEVARKEM 1199
            LTLEKVQ+LCA+K K++ EVE LR  +PK LW+                DA+  + R++ 
Sbjct: 842  LTLEKVQKLCADKDKISEEVENLRRTAPKDLWLKDLEAFESQLDKL---DAEDALERQKS 898

Query: 1198 KNKVMTEAGMKASRQVAKNPRKNNTKKANNPQVTVNDTASESVSSTMEVDDVAEAXXXXX 1019
                  + G K SRQ  KNPRKNN K A N +    +   ++ +S ME + V+E      
Sbjct: 899  VKDTNGQGGFKVSRQPPKNPRKNN-KTAKNTEAAA-EIMGQTSNSAMETESVSEEVKPKG 956

Query: 1018 XXXXXXXXXXXXKLEKLSLIDNEEDDHEVLSLKQRLAAYNLDSSPAQSESMETEVAKEVP 839
                          EK + I ++EDD EV +LK RL AY LDSSP QS +MET++  +VP
Sbjct: 957  RAASKKAPAKKQ--EKPTPISDDEDD-EVEALKDRLKAYRLDSSPEQSTTMETDM-PQVP 1012

Query: 838  AKKREQSKRAAKQKXXXXPTLTEIS-SDDENSKDDE---QMQTIPEEQMSDSDEDFXXXX 671
            A+K E SKRAA QK     T++E+S S+DE   DDE   ++  +PE +     +      
Sbjct: 1013 ARK-ETSKRAAAQK-KPVATISELSESEDEVDLDDESDVEVVPVPEAKKKGGRK------ 1064

Query: 670  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKQLLDQKLITDVLKPAENIGPSPDKKV 491
                                              Q L QKL+T++LKPAEN G SP+KKV
Sbjct: 1065 ----------PAANSRAAKPPAGTKKRGPTKKESQGLGQKLLTEMLKPAENPGISPEKKV 1114

Query: 490  RKTRASPFNKKSGTV 446
            RK RASPFNKKSG+V
Sbjct: 1115 RKMRASPFNKKSGSV 1129


>ref|XP_006439078.1| hypothetical protein CICLE_v10030505mg [Citrus clementina]
            gi|557541274|gb|ESR52318.1| hypothetical protein
            CICLE_v10030505mg [Citrus clementina]
          Length = 1455

 Score =  418 bits (1075), Expect = e-114
 Identities = 267/551 (48%), Positives = 336/551 (60%), Gaps = 8/551 (1%)
 Frame = -3

Query: 2074 KEAGVTYTMSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGTDKLSPFIKDYREHN 1895
            KEAGVTYT++GIIEEVNETTLRI ELP+RRWTQDY+EFLESI+   D    FI+ +R+++
Sbjct: 884  KEAGVTYTVTGIIEEVNETTLRIKELPIRRWTQDYREFLESIIDQNDS---FIRGFRQYS 940

Query: 1894 DDTTVHFEVIMSEENLKMAKQEGLLKKFKLTTTISTSNMHLFDTNGVIKKYDTPEQILEE 1715
            DDTTV FEV +SEE++   KQEGLLKKFKLTTTISTSNMHLFD+ GVIKKYDTPEQILEE
Sbjct: 941  DDTTVDFEVFLSEESMMRTKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEQILEE 1000

Query: 1714 FFHLRLQFYXXXXXXXXXXXXXXXXXXXXXVRFILGVVKGEIIVSNRKRAELFIELHQKG 1535
            FFH+RL+FY                     VRFILGVV GEI+V+NRKR +L +EL QKG
Sbjct: 1001 FFHIRLEFYEKRKKVQLENLELELLKLENKVRFILGVVNGEIVVNNRKRTDLLLELRQKG 1060

Query: 1534 FTPFPXXXXKIEAAVAGATEDADESEESPEVLRNSGVQASDYDYLLSMAIGTLTLEKVQE 1355
            FTPFP     IEA VAGAT++ +ESEE+PEV+  +GVQ+ DYDYLLSMAIGTLTLEKVQ 
Sbjct: 1061 FTPFPKNSKSIEAVVAGATDETEESEENPEVV--NGVQSIDYDYLLSMAIGTLTLEKVQG 1118

Query: 1354 LCAEKAKLTNEVEELRGASPKSLWMXXXXXXXXXXXXXXKNDAKAEVARKEMKNKVMTEA 1175
            L A++ KL  EV++LR A+P+SLW+              K+DA+AE  R ++K    ++A
Sbjct: 1119 LLADRDKLNEEVDDLRKATPESLWV-KDLDALDMQLDLDKSDARAEEERMKIKGNGNSDA 1177

Query: 1174 GMK-ASRQVAKNPRKNNTKKANNPQVTVNDTASESVSSTMEVDDVAEAXXXXXXXXXXXX 998
            G K  +++  KN RKN+ KK+NN + T          +  E+D+V +             
Sbjct: 1178 GPKIVAKRAPKNARKND-KKSNNARAT---------EAMGEMDNVTKV-----VKPKGRA 1222

Query: 997  XXXXXKLEKLSLIDNEEDDHEVLSLKQRLAAYN-------LDSSPAQSESMETEVAKEVP 839
                   EKL   D+EE+D EV  LKQRLA  N       L+ SP QS  METE   +VP
Sbjct: 1223 GLKKAPAEKL---DDEEED-EVPDLKQRLAKLNEQLASTKLEPSPDQSGVMETEKV-QVP 1277

Query: 838  AKKREQSKRAAKQKXXXXPTLTEISSDDENSKDDEQMQTIPEEQMSDSDEDFXXXXXXXX 659
            AKK+E SKR A QK     T+    S+DE   DD++   I   +                
Sbjct: 1278 AKKKEPSKRTAAQK--KAVTVETSDSEDEIIIDDDEAFEIAAPEAGKK------------ 1323

Query: 658  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXKQLLDQKLITDVLKPAENIGPSPDKKVRKTR 479
                                         +  L Q+L+T++LKP E+   SP+KKVRK R
Sbjct: 1324 GGRKAAGNTKAAKPAVETKKRGPAKKQQPEASLGQRLLTEMLKPTES---SPEKKVRKMR 1380

Query: 478  ASPFNKKSGTV 446
            ASPFNKKSG++
Sbjct: 1381 ASPFNKKSGSM 1391


>gb|AAN85207.1| DNA topoisomerase II [Nicotiana tabacum] gi|26984168|gb|AAN85208.1|
            DNA topoisomerase II [Nicotiana tabacum]
          Length = 1482

 Score =  410 bits (1054), Expect = e-111
 Identities = 260/547 (47%), Positives = 326/547 (59%), Gaps = 4/547 (0%)
 Frame = -3

Query: 2074 KEAGVTYTMSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGTDKLS-PFIKDYREH 1898
            KEAG TYT++GIIEEVNETTLRI+ELPVRRWT+DYK+FLES+    DK   PFIK+ R +
Sbjct: 884  KEAGATYTVTGIIEEVNETTLRISELPVRRWTEDYKQFLESMTVSNDKAKDPFIKEVRAY 943

Query: 1897 NDDTTVHFEVIMSEENLKMAKQEGLLKKFKLTTTISTSNMHLFDTNGVIKKYDTPEQILE 1718
             D+ +V FEVIMSEENL +A+QEGLLKKFKL TTISTSNMHLFD+NG IKKYD PE ILE
Sbjct: 944  GDENSVCFEVIMSEENLILAQQEGLLKKFKLATTISTSNMHLFDSNGKIKKYDNPEDILE 1003

Query: 1717 EFFHLRLQFYXXXXXXXXXXXXXXXXXXXXXVRFILGVVKGEIIVSNRKRAELFIELHQK 1538
            EF+H+RL++Y                     V+FILGVVK EIIV+NRKRA+L +EL +K
Sbjct: 1004 EFYHVRLEYYEKRKKALLEILELELLRIENKVKFILGVVKVEIIVNNRKRADLLLELKEK 1063

Query: 1537 GFTPFPXXXXKIEAAVAGATEDADESEESPEVLRNSGVQASDYDYLLSMAIGTLTLEKVQ 1358
            GFTPFP     +EA VA  ++DA++SEE      N GV+A DYDYLLSM IGTLTLEKVQ
Sbjct: 1064 GFTPFP-KKKAVEAVVADTSDDAEDSEEE----LNRGVRAGDYDYLLSMPIGTLTLEKVQ 1118

Query: 1357 ELCAEKAKLTNEVEELRGASPKSLWMXXXXXXXXXXXXXXKNDAKAEVARKEMKNKVMTE 1178
            ELCAE+ +L  EVE++R A+PK LW+              K D +AE AR+++K KVM  
Sbjct: 1119 ELCAERDQLNGEVEDMRNATPKLLWLKDLDVLEKQLDEQDKIDIQAEEAREKIKKKVMNA 1178

Query: 1177 AGMKASRQVAKNPRKNNTKKANNPQVTVNDTASESVSSTMEVDDVAEAXXXXXXXXXXXX 998
            AG+KA +     PRK N KKA+  + T       S  ++    +V E             
Sbjct: 1179 AGLKAPK---PKPRK-NVKKASVVESTAEPMDRVSCFNSGNRSNVTEVVKPKARGGSKKA 1234

Query: 997  XXXXXKLEKLSLIDNEEDDHEVLSLKQRLAAYNLDSSPAQS-ESMETEVAKEVPAKKREQ 821
                  +      + EE+D EVL+LK RLAAYNL+SSP  S E+METE  K   A+K+  
Sbjct: 1235 PAKAKPIAVED--EEEEEDDEVLALKDRLAAYNLNSSPDHSAEAMETEAPK---AQKKAP 1289

Query: 820  SKRAAKQKXXXXPTLTEISSDDENSKDDEQMQTIPEEQMSDSDEDFXXXXXXXXXXXXXX 641
            +++AA +K     TL  I+   E            E ++SD DE                
Sbjct: 1290 TRKAAAKK----KTLPSIADVSEGE---------DEIEISDDDESEPEVAVGGKKKGGRK 1336

Query: 640  XXXXXXXXXXXXXXXXXXXXXXXKQL-LDQKLITDVLKPAENI-GPSPDKKVRKTRASPF 467
                                   + + + QKLIT +LKPAEN    SP+KKVRK RASPF
Sbjct: 1337 PATAKAAPAAAKQPPKKRGPANKQAVGIGQKLITSILKPAENTDNSSPEKKVRKMRASPF 1396

Query: 466  NKKSGTV 446
            N+KSG V
Sbjct: 1397 NEKSGAV 1403


>gb|EYU27037.1| hypothetical protein MIMGU_mgv1a000169mg [Mimulus guttatus]
          Length = 1503

 Score =  407 bits (1045), Expect = e-110
 Identities = 248/544 (45%), Positives = 321/544 (59%), Gaps = 1/544 (0%)
 Frame = -3

Query: 2074 KEAGVTYTMSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGTDKLS-PFIKDYREH 1898
            KEAG +YT++GIIEEV+ETTL ITELP+RRWTQDYKEFLESI    DK   PFI+  R++
Sbjct: 902  KEAGFSYTVTGIIEEVDETTLTITELPIRRWTQDYKEFLESISAENDKSKDPFIEGCRDN 961

Query: 1897 NDDTTVHFEVIMSEENLKMAKQEGLLKKFKLTTTISTSNMHLFDTNGVIKKYDTPEQILE 1718
            +    +HF V +SE NL +AKQEGLLKKFKLTTT+STSNMHLFD+ GVIKKYD+PEQILE
Sbjct: 962  SGGEIIHFAVYLSETNLLVAKQEGLLKKFKLTTTMSTSNMHLFDSKGVIKKYDSPEQILE 1021

Query: 1717 EFFHLRLQFYXXXXXXXXXXXXXXXXXXXXXVRFILGVVKGEIIVSNRKRAELFIELHQK 1538
            EFF++RL+FY                      RFI GVV+G I+VSNRK+A+LF+EL  K
Sbjct: 1022 EFFYIRLEFYEKRKKALLANLELDMLKCDNKYRFIRGVVEGTIVVSNRKKADLFLELKAK 1081

Query: 1537 GFTPFPXXXXKIEAAVAGATEDADESEESPEVLRNSGVQASDYDYLLSMAIGTLTLEKVQ 1358
            GFTPFP      E AVAGAT+D +E+E++ EV    GV ASDYDYLLS+AIGTLT EK+Q
Sbjct: 1082 GFTPFPKKKNTPEVAVAGATDDTEETEDNTEVEIAKGVSASDYDYLLSLAIGTLTAEKLQ 1141

Query: 1357 ELCAEKAKLTNEVEELRGASPKSLWMXXXXXXXXXXXXXXKNDAKAEVARKEMKNKVMTE 1178
            EL  E+ +LT EVE+L+ ++ KSLW               KN  K    + E   + +  
Sbjct: 1142 ELRDERERLTQEVEDLKKSTVKSLWTKDLDALEAKIIEDLKNSEK----KWEEDRQRIQG 1197

Query: 1177 AGMKASRQVAKNPRKNNTKKANNPQVTVNDTASESVSSTMEVDDVAEAXXXXXXXXXXXX 998
               K +R +AKNPRK NTKKA   + +  +    S ++  E D VAE             
Sbjct: 1198 GETKIARPLAKNPRK-NTKKATTKKESTAEHMDVSDNTVTETDKVAE---IKKPRGKAAA 1253

Query: 997  XXXXXKLEKLSLIDNEEDDHEVLSLKQRLAAYNLDSSPAQSESMETEVAKEVPAKKREQS 818
                  + K+    +E+DD  V  L+QR+AAYN DSSP ++E METE+  ++  KK+E +
Sbjct: 1254 AKKKAPVAKVVAEADEDDDDGVAELRQRIAAYNFDSSPDRAEDMETEL-PQLQTKKKEPT 1312

Query: 817  KRAAKQKXXXXPTLTEISSDDENSKDDEQMQTIPEEQMSDSDEDFXXXXXXXXXXXXXXX 638
            KRAA +K         I SDDE   +D+ ++ I ++     D+                 
Sbjct: 1313 KRAAPRKKQ-----VSIVSDDE---EDDDIEIIDDDDFEPEDK--------KKKGGRKPA 1356

Query: 637  XXXXXXXXXXXXXXXXXXXXXXKQLLDQKLITDVLKPAENIGPSPDKKVRKTRASPFNKK 458
                                   QL+ QKLIT+VLKP      SP+KKVR+ RASPFNKK
Sbjct: 1357 NPKAAAAKPPAGAKKRGPASKQSQLVGQKLITEVLKPTAAADDSPEKKVRRMRASPFNKK 1416

Query: 457  SGTV 446
            S ++
Sbjct: 1417 SSSI 1420


>ref|XP_007220582.1| hypothetical protein PRUPE_ppa000202mg [Prunus persica]
            gi|462417044|gb|EMJ21781.1| hypothetical protein
            PRUPE_ppa000202mg [Prunus persica]
          Length = 1471

 Score =  399 bits (1024), Expect = e-108
 Identities = 223/423 (52%), Positives = 276/423 (65%), Gaps = 1/423 (0%)
 Frame = -3

Query: 2074 KEAGVTYTMSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGTDKLS-PFIKDYREH 1898
            KE+GV+YT+ G+IEE NETT+RI+ELP+RRWTQDYKEFLESI  G DK   PFI+ + +H
Sbjct: 890  KESGVSYTVCGVIEEGNETTVRISELPIRRWTQDYKEFLESISQGNDKAKDPFIEGFTQH 949

Query: 1897 NDDTTVHFEVIMSEENLKMAKQEGLLKKFKLTTTISTSNMHLFDTNGVIKKYDTPEQILE 1718
            +D +TV   V + EENL  A+QEGLLKKFKLTT+ISTSNMHLFD  GVIKKYDTPEQILE
Sbjct: 950  SDHSTVDIIVHLPEENLMAARQEGLLKKFKLTTSISTSNMHLFDPKGVIKKYDTPEQILE 1009

Query: 1717 EFFHLRLQFYXXXXXXXXXXXXXXXXXXXXXVRFILGVVKGEIIVSNRKRAELFIELHQK 1538
            EFFHLRL+FY                     VRFIL VV GEIIVSNR+RA+LF+EL QK
Sbjct: 1010 EFFHLRLEFYEKRKKVLLDNLEMELLKLENKVRFILAVVNGEIIVSNRRRADLFLELQQK 1069

Query: 1537 GFTPFPXXXXKIEAAVAGATEDADESEESPEVLRNSGVQASDYDYLLSMAIGTLTLEKVQ 1358
            GFTPFP      E  VAGA ED +E+EE+ E    +G + SDY+YL+SMAIGTLT+E+VQ
Sbjct: 1070 GFTPFPKKTKAQEPEVAGAIEDTEETEENSESASGNGARISDYEYLISMAIGTLTIERVQ 1129

Query: 1357 ELCAEKAKLTNEVEELRGASPKSLWMXXXXXXXXXXXXXXKNDAKAEVARKEMKNKVMTE 1178
             LCA++ K+ NEV ELR ++P+SLW+              K++A AE A+K+ +N+V   
Sbjct: 1130 ALCADRDKVNNEVAELRNSTPRSLWLKDLDALEMELGELEKSEALAEEAKKKSRNQVKNA 1189

Query: 1177 AGMKASRQVAKNPRKNNTKKANNPQVTVNDTASESVSSTMEVDDVAEAXXXXXXXXXXXX 998
               K SR   KNPRKNN KKANN +    ++   S S   E++   E             
Sbjct: 1190 PAAKVSRPAPKNPRKNN-KKANNAEAAA-ESRETSSSFVFEMEKAPEIVKRKVGAVAKKA 1247

Query: 997  XXXXXKLEKLSLIDNEEDDHEVLSLKQRLAAYNLDSSPAQSESMETEVAKEVPAKKREQS 818
                   +  S +   +DD EVL LK RLAAYNLDSSP  S   ETEV +E P +++E S
Sbjct: 1248 PAGKK--QAKSAVVLSDDDDEVLELKDRLAAYNLDSSPENSAGKETEVPQE-PVQRKEPS 1304

Query: 817  KRA 809
            KRA
Sbjct: 1305 KRA 1307


>ref|XP_004165384.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 2-like [Cucumis
            sativus]
          Length = 1460

 Score =  398 bits (1023), Expect = e-108
 Identities = 251/559 (44%), Positives = 319/559 (57%), Gaps = 16/559 (2%)
 Frame = -3

Query: 2074 KEAGVTYTMSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGTDK---------LSP 1922
            KE G TYT+SGIIEEV++TTLRI ELPVRRWT DYK+FL+S+     K           P
Sbjct: 852  KEGGTTYTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDP 911

Query: 1921 FIKDYREHNDDTTVHFEVIMSEENLKMAKQEGLLKKFKLTTTISTSNMHLFDTNGVIKKY 1742
            FI+    H+DD  V  +V ++EEN+ +A QEGL KKFKLTTT+STSNMHLFD NGVIKKY
Sbjct: 912  FIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKY 971

Query: 1741 DTPEQILEEFFHLRLQFYXXXXXXXXXXXXXXXXXXXXXVRFILGVVKGEIIVSNRKRAE 1562
            DTPEQILEEFF LRL+FY                     VRFIL VV  EI VSNRK+ +
Sbjct: 972  DTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVD 1031

Query: 1561 LFIELHQKGFTPFPXXXXKIEAAVAGATEDADESEESPEVLRNSGVQASDYDYLLSMAIG 1382
            LF EL  KGFTPFP     +E  +AGA+ + DE+EESPEV++  G + SDY+YLL++ IG
Sbjct: 1032 LFHELQAKGFTPFPKKTKSVEPEIAGASNETDEAEESPEVVK--GERISDYEYLLALPIG 1089

Query: 1381 TLTLEKVQELCAEKAKLTNEVEELRGASPKSLWMXXXXXXXXXXXXXXKNDAKAEVARKE 1202
            TLT+EKVQELC+++ KL  EV++LR A+PKSLW+              +NDA+    RK+
Sbjct: 1090 TLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQ 1149

Query: 1201 MKNKVMTEAGMKASRQVAKNPRKNNTKKANNPQVTVNDTASESVSSTMEVDDVAEAXXXX 1022
             + K   +   K SR   K PR  N+KK +N + TV ++   + SST    +VA      
Sbjct: 1150 QREKANIDLKPKVSRNAPKAPR--NSKKTSNVE-TVTESMDTTYSST--TTEVANNPVVK 1204

Query: 1021 XXXXXXXXXXXXXKLEKLSLIDNEEDDH--EVLSLKQRLAAYNLDSSPAQSE--SMETEV 854
                         K  K +++D++EDD   EVL LK RLAAY ++SSP  SE  +METEV
Sbjct: 1205 PKGKAAPRKAPAKKKGKAAVLDDDEDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETEV 1264

Query: 853  --AKEVPAKKREQSKRAAKQKXXXXPTLTEISSDDENSKDDEQMQTIPEEQMSDSDEDFX 680
               ++  AKK+E SKRA  +K     +     SDD+N  D E  +  P            
Sbjct: 1265 QEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGR--- 1321

Query: 679  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKQLLDQKLITDVLKP-AENIGPSP 503
                                                   L QKLIT +L+P AEN G SP
Sbjct: 1322 ---------------GGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSGISP 1366

Query: 502  DKKVRKTRASPFNKKSGTV 446
            +KKVRK RASPFNKKSG++
Sbjct: 1367 EKKVRKIRASPFNKKSGSL 1385


>ref|XP_004149716.1| PREDICTED: DNA topoisomerase 2-like [Cucumis sativus]
          Length = 1459

 Score =  398 bits (1023), Expect = e-108
 Identities = 251/559 (44%), Positives = 319/559 (57%), Gaps = 16/559 (2%)
 Frame = -3

Query: 2074 KEAGVTYTMSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGTDK---------LSP 1922
            KE G TYT+SGIIEEV++TTLRI ELPVRRWT DYK+FL+S+     K           P
Sbjct: 852  KEGGTTYTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDP 911

Query: 1921 FIKDYREHNDDTTVHFEVIMSEENLKMAKQEGLLKKFKLTTTISTSNMHLFDTNGVIKKY 1742
            FI+    H+DD  V  +V ++EEN+ +A QEGL KKFKLTTT+STSNMHLFD NGVIKKY
Sbjct: 912  FIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKY 971

Query: 1741 DTPEQILEEFFHLRLQFYXXXXXXXXXXXXXXXXXXXXXVRFILGVVKGEIIVSNRKRAE 1562
            DTPEQILEEFF LRL+FY                     VRFIL VV  EI VSNRK+ +
Sbjct: 972  DTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVD 1031

Query: 1561 LFIELHQKGFTPFPXXXXKIEAAVAGATEDADESEESPEVLRNSGVQASDYDYLLSMAIG 1382
            LF EL  KGFTPFP     +E  +AGA+ + DE+EESPEV++  G + SDY+YLL++ IG
Sbjct: 1032 LFHELQAKGFTPFPKKTKSVEPEIAGASNETDEAEESPEVVK--GERISDYEYLLALPIG 1089

Query: 1381 TLTLEKVQELCAEKAKLTNEVEELRGASPKSLWMXXXXXXXXXXXXXXKNDAKAEVARKE 1202
            TLT+EKVQELC+++ KL  EV++LR A+PKSLW+              +NDA+    RK+
Sbjct: 1090 TLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQ 1149

Query: 1201 MKNKVMTEAGMKASRQVAKNPRKNNTKKANNPQVTVNDTASESVSSTMEVDDVAEAXXXX 1022
             + K   +   K SR   K PR  N+KK +N + TV ++   + SST    +VA      
Sbjct: 1150 QREKANIDLKPKVSRNAPKAPR--NSKKTSNVE-TVTESMDTTYSST--TTEVANNPVVK 1204

Query: 1021 XXXXXXXXXXXXXKLEKLSLIDNEEDDH--EVLSLKQRLAAYNLDSSPAQSE--SMETEV 854
                         K  K +++D++EDD   EVL LK RLAAY ++SSP  SE  +METEV
Sbjct: 1205 PKGKAAPRKAPAKKKGKAAVLDDDEDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETEV 1264

Query: 853  --AKEVPAKKREQSKRAAKQKXXXXPTLTEISSDDENSKDDEQMQTIPEEQMSDSDEDFX 680
               ++  AKK+E SKRA  +K     +     SDD+N  D E  +  P            
Sbjct: 1265 QEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGR--- 1321

Query: 679  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKQLLDQKLITDVLKP-AENIGPSP 503
                                                   L QKLIT +L+P AEN G SP
Sbjct: 1322 ----------------GGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSGISP 1365

Query: 502  DKKVRKTRASPFNKKSGTV 446
            +KKVRK RASPFNKKSG++
Sbjct: 1366 EKKVRKIRASPFNKKSGSL 1384


>ref|XP_006838283.1| hypothetical protein AMTR_s00103p00101630 [Amborella trichopoda]
            gi|548840751|gb|ERN00852.1| hypothetical protein
            AMTR_s00103p00101630 [Amborella trichopoda]
          Length = 1505

 Score =  389 bits (999), Expect = e-105
 Identities = 229/462 (49%), Positives = 293/462 (63%), Gaps = 1/462 (0%)
 Frame = -3

Query: 2074 KEAGVTYTMSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGTDKLS-PFIKDYREH 1898
            KE GV YT+SGI+EE+NETTLRITELP+RRWT+DYK +LES+ TG++K   PFI DY+EH
Sbjct: 897  KEGGVGYTVSGIVEEINETTLRITELPIRRWTEDYKVYLESLRTGSEKTKEPFIVDYKEH 956

Query: 1897 NDDTTVHFEVIMSEENLKMAKQEGLLKKFKLTTTISTSNMHLFDTNGVIKKYDTPEQILE 1718
            N DT VHF+V++ EEN+K+++QEGL+K FKLTTTISTSNMHLF+  GVIKKYDTPEQILE
Sbjct: 957  NTDTRVHFDVLLPEENMKISQQEGLMKMFKLTTTISTSNMHLFNAKGVIKKYDTPEQILE 1016

Query: 1717 EFFHLRLQFYXXXXXXXXXXXXXXXXXXXXXVRFILGVVKGEIIVSNRKRAELFIELHQK 1538
            EFFHLRL +Y                      RFILGVV GEI+VS RKRA+L +EL  K
Sbjct: 1017 EFFHLRLDYYGKRKKVLLDNLELELLKLDNKARFILGVVNGEIVVSKRKRADLVLELRDK 1076

Query: 1537 GFTPFPXXXXKIEAAVAGATEDADESEESPEVLRNSGVQASDYDYLLSMAIGTLTLEKVQ 1358
            GFTPFP     +EAA+AGAT   +E EESPEV  + G+ ASDYDYLLSMAIGTLT+EKVQ
Sbjct: 1077 GFTPFPKKSKNVEAALAGATPVDEEGEESPEV-DDRGINASDYDYLLSMAIGTLTIEKVQ 1135

Query: 1357 ELCAEKAKLTNEVEELRGASPKSLWMXXXXXXXXXXXXXXKNDAKAEVARKEMKNKVMTE 1178
            ELCAEK KL ++V+ELRG +PK+LW+                +AK +    E+ N V   
Sbjct: 1136 ELCAEKDKLEHDVKELRGLTPKALWIKDLDAFLAQLDAEAVQEAKDD--EYELNNMVSDA 1193

Query: 1177 AGMKASRQVAKNPRKNNTKKANNPQVTVNDTASESVSSTMEVDDVAEAXXXXXXXXXXXX 998
            A  K  RQV KNPRKN  K A  P   V+  AS++ ++ +       A            
Sbjct: 1194 A--KIFRQVGKNPRKNTKKPA--PAEHVDTDASDTTTTEVAAKPKKRAPKKAPTK----- 1244

Query: 997  XXXXXKLEKLSLIDNEEDDHEVLSLKQRLAAYNLDSSPAQSESMETEVAKEVPAKKREQS 818
                   +K+ + D E+D   +L L  RLA YN++SSP  ++ MET++      ++RE S
Sbjct: 1245 -------KKVDVEDMEDD--LLLDLNARLAKYNIESSPEHAD-METDL-----PERREPS 1289

Query: 817  KRAAKQKXXXXPTLTEISSDDENSKDDEQMQTIPEEQMSDSD 692
            KRA  +       +    SDDE S+  E+++   EE+  D D
Sbjct: 1290 KRAVSKPQQVYADI----SDDE-SEHLEEIEEEKEEEQEDED 1326


>ref|XP_007009329.1| Topoisomerase II isoform 3 [Theobroma cacao]
            gi|508726242|gb|EOY18139.1| Topoisomerase II isoform 3
            [Theobroma cacao]
          Length = 1244

 Score =  387 bits (995), Expect = e-105
 Identities = 214/347 (61%), Positives = 253/347 (72%)
 Frame = -3

Query: 2074 KEAGVTYTMSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGTDKLSPFIKDYREHN 1895
            KEAGVTYT++GIIEEV+ETTLRITELPVRRWTQDY+EFLESI+TG D   PFIK++R+++
Sbjct: 885  KEAGVTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESIITGND---PFIKEFRQYS 941

Query: 1894 DDTTVHFEVIMSEENLKMAKQEGLLKKFKLTTTISTSNMHLFDTNGVIKKYDTPEQILEE 1715
            DDTTV FEVI++EEN+ +AKQEGLLKKFKLTTTISTSNMHLFD+ G+IKKYDTPEQILEE
Sbjct: 942  DDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTSNMHLFDSKGMIKKYDTPEQILEE 1001

Query: 1714 FFHLRLQFYXXXXXXXXXXXXXXXXXXXXXVRFILGVVKGEIIVSNRKRAELFIELHQKG 1535
            FFHLR +FY                     VRFILGVVKGEIIV+NRKRA+LF+EL  KG
Sbjct: 1002 FFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRADLFLELQTKG 1061

Query: 1534 FTPFPXXXXKIEAAVAGATEDADESEESPEVLRNSGVQASDYDYLLSMAIGTLTLEKVQE 1355
            FTPFP     +E AVAGAT+D +E+EE+ EV    G+QASDYDYLLSMAIG+LTLEKVQE
Sbjct: 1062 FTPFPKKAKTVEVAVAGATDDTEETEENSEV-SAKGLQASDYDYLLSMAIGSLTLEKVQE 1120

Query: 1354 LCAEKAKLTNEVEELRGASPKSLWMXXXXXXXXXXXXXXKNDAKAEVARKEMKNKVMTEA 1175
            LCA++ KL  EVE+LR A+PKSLW+                 A+AE A K +K +   EA
Sbjct: 1121 LCADRDKLQQEVEDLRKATPKSLWL-KDLDNLEIQLDEQDKAAQAEEAAKLVKGR--GEA 1177

Query: 1174 GMKASRQVAKNPRKNNTKKANNPQVTVNDTASESVSSTMEVDDVAEA 1034
            G +A RQ  K PRK N K+ N    TV +T   S SS ME +    A
Sbjct: 1178 GKRAQRQAPKIPRKINKKEKN--AETVTETTDISSSSAMETETAPAA 1222