BLASTX nr result
ID: Cocculus23_contig00014297
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Cocculus23_contig00014297
(1510 letters)
Database: ./nr
38,876,450 sequences; 13,856,398,315 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
sp|B5UAQ8.1|C7195_ESCCA RecName: Full=Cheilanthifoline synthase;... 345 4e-92
gb|ADB89214.1| stylopine synthase [Papaver somniferum] 343 1e-91
gb|AAU20771.1| (S)-canadine synthase [Thalictrum flavum subsp. g... 339 2e-90
gb|AHF65153.1| stylopine synthase, partial [synthetic construct] 338 5e-90
sp|B1NF19.1|C719D_ARGME RecName: Full=(S)-stylopine synthase; Sh... 334 5e-89
sp|B1NF20.1|C719E_ARGME RecName: Full=Cheilanthifoline synthase;... 333 2e-88
dbj|BAF98470.1| cytochrome P450 [Coptis japonica var. dissecta] 331 5e-88
sp|Q50LH3.1|C7192_ESCCA RecName: Full=(S)-stylopine synthase 1; ... 327 7e-87
gb|ACO90219.1| stylopine synthase [Eschscholzia californica] 327 9e-87
gb|AFI57927.1| cytochrome P450, partial [Papaver somniferum] 325 4e-86
sp|Q50LH4.1|C7193_ESCCA RecName: Full=(S)-stylopine synthase 2; ... 325 4e-86
gb|ADB89213.1| cheilanthifoline synthase [Papaver somniferum] 322 3e-85
gb|AGL76711.1| (S)-canadine synthase, partial [Coptis chinensis] 320 1e-84
sp|Q948Y1.1|C719A_COPJA RecName: Full=(S)-canadine synthase; Alt... 319 2e-84
dbj|BAG75115.1| cytochrome P450 [Eschscholzia californica] 318 4e-84
dbj|BAG75116.1| cytochrome P450 [Eschscholzia californica] 317 7e-84
gb|AFB74615.1| cytochrome P450 [Papaver somniferum] 317 1e-83
gb|AGC29953.1| CYP719A23 [Sinopodophyllum hexandrum] 306 2e-80
dbj|BAG75114.1| cytochrome P450 [Eschscholzia californica] 306 2e-80
sp|B1NF18.1|C719B_PAPSO RecName: Full=Salutaridine synthase; Alt... 305 3e-80
>sp|B5UAQ8.1|C7195_ESCCA RecName: Full=Cheilanthifoline synthase; Short=CHS; AltName:
Full=Cytochrome P450 719A5 gi|209571368|dbj|BAG75113.1|
cheilanthifoline synthase [Eschscholzia californica]
Length = 490
Score = 345 bits (884), Expect = 4e-92
Identities = 181/447 (40%), Positives = 279/447 (62%)
Frame = +2
Query: 170 MEQSNLWIIMATVFLLGLLMKLLDQSFLISGSKQQWPPGPKRFPLIGNLYQLSRGGELVH 349
ME+S LW++ ATV ++ + KLL +S IS +WP GPK+ P+IGNL+QL GGE H
Sbjct: 1 MEES-LWVVTATVVVVFAIAKLLKKSSSIS--TMEWPKGPKKLPIIGNLHQL--GGEAFH 55
Query: 350 LTLAKMAQKHGRIMTVWFGGPEPTIVLSDHELAWEVLVTKVSDYSSRTRNVMSKITSADW 529
+ LA +A+ HG +MT+W G P IV+SD + AWEVLV K SDY+ R ++KI SA+W
Sbjct: 56 VVLANLAKIHGTVMTIWVGAWRPMIVISDIDKAWEVLVNKSSDYAGRDFPEITKIISANW 115
Query: 530 NTLATSSLGPAWERFRKGLQSTTLHPRIIFSHAQLQEKDIADLTSSLEQEASLNNGIVKP 709
++ S GP W+ RKGLQ L P + S QLQE+D+ +L +S++++AS NNGI+KP
Sbjct: 116 KNISCSDSGPFWQNLRKGLQGGALAPLNVISQYQLQERDMKNLITSMQEKASKNNGILKP 175
Query: 710 XXXXXXXXXXXXXXXCFGPESSMDDLFAEGIYCAIVEAIKLEEKGHLVDVFEFTRYIPGL 889
FG +S D+ F +G++ A+ + +++ L D F+F +P
Sbjct: 176 LDYLKEETIRLLSRLIFG-QSFNDENFVKGVHLALDDLVRISGYASLADAFKFCENLPSH 234
Query: 890 KPPFKELESLKQRVKVLISSYISTHKPSSSNCYLSFLLSQGFTEDIVIANLFELFMFSVD 1069
K +E+ + +RV L+ Y+ + P +N YL FL SQ F+++++I+ + E++ VD
Sbjct: 235 KKSIREVHEVNERVVNLVKPYLVKNPP--TNTYLYFLNSQKFSDEVIISAVLEVYDLGVD 292
Query: 1070 STSNTIAWALAFVIHHEDIQQRVLTRVMNKLGGRRRMVSVEDLKTEMEYVHAVVKETVRS 1249
ST++T WAL F++ +Q+++ +++ GG R V VED+ +++ Y+ AV+KET+R
Sbjct: 293 STASTAVWALTFLVREPRVQEKLYKEIIDLTGG-ERSVKVEDV-SKLPYLQAVMKETMRM 350
Query: 1250 RPIVPWGLPRRATRDSELKGMTVREGTQVLVNLYAVLHDERVWKEPNKFMPERFLMSGSS 1429
+PI P +P + +RD+ L G V +GT ++VNLYA+ H+ +V+ EP KF+PERFL S
Sbjct: 351 KPIAPMAIPHKTSRDTSLMGKKVNKGTSIMVNLYAIHHNPKVFPEPYKFIPERFLQGQES 410
Query: 1430 GDGEDVTRMERSFISFGAGRRSCPGME 1510
G D+ ME+S + F AG R C GME
Sbjct: 411 KYG-DIKEMEQSLLPFSAGMRICAGME 436
>gb|ADB89214.1| stylopine synthase [Papaver somniferum]
Length = 494
Score = 343 bits (880), Expect = 1e-91
Identities = 183/445 (41%), Positives = 268/445 (60%), Gaps = 1/445 (0%)
Frame = +2
Query: 179 SNLWIIMATVFLLGLLMKLLDQSFLISGSKQQWPPGPKRFPLIGNLYQLSRGGELVHLTL 358
SN WI+ + ++ ++ +L S WP GPK P+IGN++ L GG + + L
Sbjct: 7 SNPWILTTSTLVVITIITMLMVFKRKKSSTMVWPTGPKTLPIIGNMHVL--GGTALQVVL 64
Query: 359 AKMAQKHGRIMTVWFGGPEPTIVLSDHELAWEVLVTKVSDYSSRTRNVMSKITSADWNTL 538
+A+ HG +MT+W G P IV+SD + AWEVLV K SDYS+R ++KI SADW T+
Sbjct: 65 HNLAKIHGNVMTIWIGSWRPVIVVSDIDRAWEVLVNKSSDYSARDMPEITKIISADWKTI 124
Query: 539 ATSSLGPAWERFRKGLQSTTLHPRIIFSHAQLQEKDIADLTSSLEQEASLNNGIVKPXXX 718
+TS GP W RKGLQ+ L P + + +Q QEKDI + SL++EA+ NNGIVKP
Sbjct: 125 STSDSGPGWSNLRKGLQNVALSPHNLAAQSQFQEKDITKMIQSLKKEAASNNGIVKPIDH 184
Query: 719 XXXXXXXXXXXXCFGPESSMDDLFAEGIYCAIVEAIKLEEKGHLVDVFEFTRYIPGLKPP 898
FG + DD + + ++ AI E I++ L + F + +Y+P K
Sbjct: 185 LKKATLRLISRLIFGQDFD-DDKYVDDMHHAIEELIRVSGYAQLAEAFYYAKYLPSHKKA 243
Query: 899 FKELESLKQRVKVLISSYISTHKPSSSNCYLSFLLSQGFTEDIVIANLFELFMFSVDSTS 1078
+++E QRVK L+ ++S + P +N YL FL SQ + E+++I +FE ++ VDSTS
Sbjct: 244 VRDVEEANQRVKKLVRPFLSLNPP--TNTYLHFLNSQKYDEEVIIFAIFEAYLLGVDSTS 301
Query: 1079 NTIAWALAFVIHHEDIQQRVLTRVMNKLGGRR-RMVSVEDLKTEMEYVHAVVKETVRSRP 1255
T AWALAF+I +Q ++ + N +V VEDL +++Y+ AV+KET+R +P
Sbjct: 302 LTTAWALAFLIREPVVQDKLYQELKNLTAKNDCEIVKVEDL-NKLQYLQAVLKETMRMKP 360
Query: 1256 IVPWGLPRRATRDSELKGMTVREGTQVLVNLYAVLHDERVWKEPNKFMPERFLMSGSSGD 1435
I P +P +A RD+ LKG + +GTQV+VN+YA+ H+E+VWKEP KFMPERFL + +
Sbjct: 361 IAPLAIPHKACRDTSLKGNKIDQGTQVMVNIYALHHNEKVWKEPFKFMPERFLQTQDVVN 420
Query: 1436 GEDVTRMERSFISFGAGRRSCPGME 1510
G+ ME+S + F AG R C GME
Sbjct: 421 GKG---MEQSLLPFSAGMRICAGME 442
>gb|AAU20771.1| (S)-canadine synthase [Thalictrum flavum subsp. glaucum]
Length = 492
Score = 339 bits (870), Expect = 2e-90
Identities = 184/448 (41%), Positives = 277/448 (61%), Gaps = 1/448 (0%)
Frame = +2
Query: 170 MEQSNLWIIMATVFLLGLLMKLLDQSFLISG-SKQQWPPGPKRFPLIGNLYQLSRGGELV 346
ME +LW++ AT+ L+ + L+ S S+ +WP GP + P+IGNL+QL GG+++
Sbjct: 1 MELVSLWLVSATLALVVAITILIPMVTSSSSFSQMKWPTGPNKLPIIGNLHQL--GGDVL 58
Query: 347 HLTLAKMAQKHGRIMTVWFGGPEPTIVLSDHELAWEVLVTKVSDYSSRTRNVMSKITSAD 526
H+ LAK+AQ HG +MTVW G P IV+SD + AWEVLV K SDY +R ++KI SA
Sbjct: 59 HVALAKLAQVHGSVMTVWIGNWRPIIVISDIDKAWEVLVNKSSDYGARDMPEITKIASAS 118
Query: 527 WNTLATSSLGPAWERFRKGLQSTTLHPRIIFSHAQLQEKDIADLTSSLEQEASLNNGIVK 706
W+T++TS G W+ RKGLQS + P I + +Q QE+D+ L +L EA+ NN IVK
Sbjct: 119 WHTISTSDAGAFWQTVRKGLQSGAMGPLNIAAQSQFQERDMKRLIQALRDEAAQNNNIVK 178
Query: 707 PXXXXXXXXXXXXXXXCFGPESSMDDLFAEGIYCAIVEAIKLEEKGHLVDVFEFTRYIPG 886
P FG ++ DD F E ++ I + I++ L + F + +Y+P
Sbjct: 179 PLDHIKKNTVRLLTRLIFG-QTFDDDKFVESMHFEIDDIIRISGYARLAEAFYYAKYLPS 237
Query: 887 LKPPFKELESLKQRVKVLISSYISTHKPSSSNCYLSFLLSQGFTEDIVIANLFELFMFSV 1066
K +E +K RV+ L+S +S++ P +N YL FLLSQ F+E+++I +FEL++ V
Sbjct: 238 HKKAEREAYLVKCRVEDLVSPLLSSNPP--TNSYLYFLLSQRFSEEVIIFCIFELYLLGV 295
Query: 1067 DSTSNTIAWALAFVIHHEDIQQRVLTRVMNKLGGRRRMVSVEDLKTEMEYVHAVVKETVR 1246
DSTS+T WALA++I + IQ+++ LG +V +ED+ ++++Y+ AVVKET+R
Sbjct: 296 DSTSSTTTWALAYLIREQAIQEKLYQDTRMTLGD-VDLVKIEDV-SKLKYLQAVVKETMR 353
Query: 1247 SRPIVPWGLPRRATRDSELKGMTVREGTQVLVNLYAVLHDERVWKEPNKFMPERFLMSGS 1426
+PI P +P + +D+ L G V +GT+++VNLYA+ H++ +W P KFMPERFL G
Sbjct: 354 MKPIAPLAIPHKTAKDTTLMGSKVAKGTRIMVNLYALHHNQNIWTNPYKFMPERFL-QGE 412
Query: 1427 SGDGEDVTRMERSFISFGAGRRSCPGME 1510
G + ME+SF+ F AG R C GM+
Sbjct: 413 DGSASN-KAMEQSFLPFSAGMRICAGMD 439
>gb|AHF65153.1| stylopine synthase, partial [synthetic construct]
Length = 511
Score = 338 bits (866), Expect = 5e-90
Identities = 178/417 (42%), Positives = 256/417 (61%), Gaps = 1/417 (0%)
Frame = +2
Query: 263 SKQQWPPGPKRFPLIGNLYQLSRGGELVHLTLAKMAQKHGRIMTVWFGGPEPTIVLSDHE 442
S WP GPK P+IGN++ L GG + + L +A+ HG +MT+W G P IV+SD +
Sbjct: 49 STMVWPTGPKTLPIIGNMHVL--GGTALQVVLHNLAKIHGNVMTIWIGSWRPVIVVSDID 106
Query: 443 LAWEVLVTKVSDYSSRTRNVMSKITSADWNTLATSSLGPAWERFRKGLQSTTLHPRIIFS 622
AWEVLV K SDYS+R ++KI SADW T++TS GP W RKGLQ+ L P + +
Sbjct: 107 RAWEVLVNKSSDYSARDMPEITKIISADWKTISTSDSGPGWSNLRKGLQNVALSPHNLAA 166
Query: 623 HAQLQEKDIADLTSSLEQEASLNNGIVKPXXXXXXXXXXXXXXXCFGPESSMDDLFAEGI 802
+Q QEKDI + SL++EA+ NNGIVKP FG + DD + + +
Sbjct: 167 QSQFQEKDITKMIQSLKKEAASNNGIVKPIDHLKKATLRLISRLIFGQDFD-DDKYVDDM 225
Query: 803 YCAIVEAIKLEEKGHLVDVFEFTRYIPGLKPPFKELESLKQRVKVLISSYISTHKPSSSN 982
+ AI E I++ L + F + +Y+P K +++E QRVK L+ ++S + P +N
Sbjct: 226 HHAIEELIRVSGYAQLAEAFYYAKYLPSHKKAVRDVEEANQRVKKLVRPFLSLNPP--TN 283
Query: 983 CYLSFLLSQGFTEDIVIANLFELFMFSVDSTSNTIAWALAFVIHHEDIQQRVLTRVMNKL 1162
YL FL SQ + E+++I +FE ++ VDSTS T AWALAF+I +Q ++ + N
Sbjct: 284 TYLHFLNSQKYDEEVIIFAIFEAYLLGVDSTSLTTAWALAFLIREPVVQDKLYQELKNLT 343
Query: 1163 GGRR-RMVSVEDLKTEMEYVHAVVKETVRSRPIVPWGLPRRATRDSELKGMTVREGTQVL 1339
+V VEDL +++Y+ AV+KET+R +PI P +P +A RD+ LKG + +GTQV+
Sbjct: 344 AKNDCEIVKVEDL-NKLQYLQAVLKETMRMKPIAPLAIPHKACRDTSLKGNKIDQGTQVM 402
Query: 1340 VNLYAVLHDERVWKEPNKFMPERFLMSGSSGDGEDVTRMERSFISFGAGRRSCPGME 1510
VN+YA+ H+E+VWKEP KFMPERFL + +G+ ME+S + F AG R C GME
Sbjct: 403 VNIYALHHNEKVWKEPFKFMPERFLQTQDVVNGKG---MEQSLLPFSAGMRICAGME 456
>sp|B1NF19.1|C719D_ARGME RecName: Full=(S)-stylopine synthase; Short=STS; AltName:
Full=Cytochrome P450 719A13 gi|148841092|gb|ABR14721.1|
stylopine synthase [Argemone mexicana]
Length = 504
Score = 334 bits (857), Expect = 5e-89
Identities = 179/458 (39%), Positives = 273/458 (59%), Gaps = 8/458 (1%)
Frame = +2
Query: 161 QREMEQSNLWIIMA-TVFLLGLLMKLLDQSFLI------SGSKQQWPPGPKRFPLIGNLY 319
++ M ++ WI+ + T +L+ LL F+I S SK WP GPK P+IGN+
Sbjct: 3 EKIMTNNSPWILTSSTTTTTTILLSLLFTIFIILRRNKSSSSKMVWPTGPKTLPIIGNMN 62
Query: 320 QLSRGGELVHLTLAKMAQKHGRIMTVWFGGPEPTIVLSDHELAWEVLVTKVSDYSSRTRN 499
L GG +H+ L +A+ +G +MT+W G P IV+SD + AWEVLV K SDYS+R
Sbjct: 63 IL--GGTALHVVLHNLAKTYGNVMTIWIGSWRPVIVVSDIDRAWEVLVNKSSDYSARDMP 120
Query: 500 VMSKITSADWNTLATSSLGPAWERFRKGLQSTTLHPRIIFSHAQLQEKDIADLTSSLEQE 679
++K+ +ADW T+++S GP W RKGLQ+ L P+ + S ++ QE+DI +L++E
Sbjct: 121 EITKLATADWKTISSSDSGPFWTNLRKGLQNVALSPQNLSSQSKFQERDIIKTIQNLKEE 180
Query: 680 ASLNNGIVKPXXXXXXXXXXXXXXXCFGPESSMDDLFAEGIYCAIVEAIKLEEKGHLVDV 859
A +NNGIVKP +G + D+ + E ++ I E I++ L +
Sbjct: 181 AKMNNGIVKPLDHLKKAMVRLISRLIYGQDFDNDE-YVEEMHHTIEELIRVSGYARLAEA 239
Query: 860 FEFTRYIPGLKPPFKELESLKQRVKVLISSYISTHKPSSSNCYLSFLLSQGFTEDIVIAN 1039
F + +Y+P K +E+ QRV+ L+ +S + P+ N YL FL SQ + ++++I
Sbjct: 240 FYYAKYLPSHKKAVREVLQANQRVQNLVRPLLSLNSPT--NTYLHFLRSQNYEDEVIIFA 297
Query: 1040 LFELFMFSVDSTSNTIAWALAFVIHHEDIQQRVLTRVMNKLGGR-RRMVSVEDLKTEMEY 1216
+FE ++ VDSTS+T AWALA++I ++Q+++ + N R+MV EDL +++Y
Sbjct: 298 IFEAYLLGVDSTSSTTAWALAYLIREPNVQEKLYEELKNFTNDNDRKMVKFEDLN-KLQY 356
Query: 1217 VHAVVKETVRSRPIVPWGLPRRATRDSELKGMTVREGTQVLVNLYAVLHDERVWKEPNKF 1396
+ AVVKET+R +PI P +P +A R++ L G V +GT+V+VN+YA+ H++ VWKEP KF
Sbjct: 357 LQAVVKETMRMKPIAPLAIPHKACRETSLMGRKVNQGTRVMVNIYALHHNQNVWKEPYKF 416
Query: 1397 MPERFLMSGSSGDGEDVTRMERSFISFGAGRRSCPGME 1510
PERFL DG D ME+S + F AG R C GME
Sbjct: 417 NPERFLQKNQ--DGVDGKAMEQSLLPFSAGMRICAGME 452
>sp|B1NF20.1|C719E_ARGME RecName: Full=Cheilanthifoline synthase; Short=CHS; AltName:
Full=Cytochrome P450 719A14 gi|148841094|gb|ABR14722.1|
cheilanthifoline synthase [Argemone mexicana]
Length = 494
Score = 333 bits (853), Expect = 2e-88
Identities = 174/444 (39%), Positives = 275/444 (61%), Gaps = 2/444 (0%)
Frame = +2
Query: 185 LWIIMATVFL-LGLLMKLLDQSFLISGSKQQWPPGPKRFPLIGNLYQLSRGGELVHLTLA 361
+W+I++TV + LG+ LL +S S S +WP GPK+ P+IGNL+QL GG++ H+ LA
Sbjct: 5 IWLIISTVIIVLGIAKFLLGKSSSSSLSTMEWPVGPKKLPIIGNLHQL--GGDVFHVVLA 62
Query: 362 KMAQKHGRIMTVWFGGPEPTIVLSDHELAWEVLVTKVSDYSSRTRNVMSKITSADWNTLA 541
+A+ +G + T+W G P I++SD + AWEVLV K SDYS+R ++KI SA+W ++
Sbjct: 63 NLAKVYGSVFTIWVGSWRPMIIVSDIDKAWEVLVNKSSDYSARDMPDITKIISANWKNIS 122
Query: 542 TSSLGPAWERFRKGLQSTTLHPRIIFSHAQLQEKDIADLTSSLEQEASLNNGIVKPXXXX 721
S GP W RKGLQ L P + S LQE+D+ +L +S+ ++AS NGI+KP
Sbjct: 123 CSDSGPFWHNLRKGLQGVALTPLNVASQYHLQERDMKNLINSMYKDASRKNGILKPLDYL 182
Query: 722 XXXXXXXXXXXCFGPESSMDDLFAEGIYCAIVEAIKLEEKGHLVDVFEFTRYIPGLKPPF 901
FG + D+ G++ A+ + +++ L D F+F +P K
Sbjct: 183 KEETVRLLSRLIFG-QDFQDEKLVVGMHHALDDLVRISGYASLADAFKFCENLPSHKKSI 241
Query: 902 KELESLKQRVKVLISSYISTHKPSSSNCYLSFLLSQGFTEDIVIANLFELFMFSVDSTSN 1081
+E+ +K+RV+ LI +I ++ P +N YL FL +Q F EDI+I+ + E++ VDST++
Sbjct: 242 REVHEVKKRVENLIRPHIVSNPP--TNTYLYFLKTQDFNEDIIISAILEVYDLGVDSTAS 299
Query: 1082 TIAWALAFVIHHEDIQQRVLTRVMNKLGGRRRMVSVEDLKTEMEYVHAVVKETVRSRPIV 1261
T WAL F++ ++IQ+++ ++N GG +R V VED+ +M Y+ AV+KET+R +PI
Sbjct: 300 TTVWALTFLVREQEIQEKLYREIVNVTGG-KRSVKVEDV-NKMPYLQAVMKETMRMKPIA 357
Query: 1262 PWGLPRRATRDSELKGMTVREGTQVLVNLYAVLHDERVWKEPNKFMPERFLMSGSSGDG- 1438
P +P + ++D+ L G + +G+ ++VNLYA+ H+ +V+ EP KFMPERFL +S +
Sbjct: 358 PMAIPHKTSKDTSLMGKKINKGSVIMVNLYAIHHNPKVFPEPYKFMPERFLKDVNSDESL 417
Query: 1439 EDVTRMERSFISFGAGRRSCPGME 1510
++ ME S ++F AG R C GME
Sbjct: 418 GNIKTMESSLLAFSAGMRICAGME 441
>dbj|BAF98470.1| cytochrome P450 [Coptis japonica var. dissecta]
Length = 491
Score = 331 bits (849), Expect = 5e-88
Identities = 179/451 (39%), Positives = 271/451 (60%), Gaps = 4/451 (0%)
Frame = +2
Query: 170 MEQSNLWIIMATVFLLGLLMKLLDQSFLISGSKQQWPPGPKRFPLIGNLYQLSRGGELVH 349
ME S LW+I +TV ++ ++ ++ S S SK++WP GPKR P+IGNL+ L GG+L+H
Sbjct: 1 MEGSFLWLIGSTVAIVLVITTIVRMSSSSSSSKKKWPSGPKRLPIIGNLHLL--GGDLLH 58
Query: 350 LTLAKMAQKHGRIMTVWFGGPEPTIVLSDHELAWEVLVTKVSDYSSRTRNVMSKITSADW 529
+TLAK+A+ HG +MT+W G P IV+SD AWEVLV+K ++Y R + K +
Sbjct: 59 VTLAKLAKVHGSVMTIWIGRWRPIIVISDINSAWEVLVSKSAEYGQRDTPDIFKTLTVGQ 118
Query: 530 NTLATSSLGPAWERFRKGLQSTTLHPRIIFSHAQLQEKDIADLTSSLEQEASLNNGIVKP 709
N ++ S +GP W RKGLQ+ L P + + Q +E+D+ L + +EA NGI+KP
Sbjct: 119 NNISMSDIGPFWHNVRKGLQNGALSPLNVAAQTQFREEDVKRLIHEMSREALNKNGIIKP 178
Query: 710 XXXXXXXXXXXXXXXCFGPESSMDDLFAEGIYCAIVEAIKLEEKGHLVDVFEFTRYIPGL 889
FGP +D F E + I + ++L L + F + +Y+P
Sbjct: 179 LDHMKKNTARLLGRLIFGPTFD-NDKFVESVLYEIEDVLRLSGYARLTEAFYYAKYLPSQ 237
Query: 890 KPPFKELESLKQRVKVLISSYISTHKPSSSNCYLSFLLSQGFTEDIVIANLFELFMFSVD 1069
K +E K R++ L+ +S++ P +N YL FL SQ ++++I+I FELF+ VD
Sbjct: 238 KKVAREAYLAKYRIEELMRPLLSSNPP--TNSYLYFLQSQNYSKEIIIFCTFELFLLGVD 295
Query: 1070 STSNTIAWALAFVIHHEDIQQRVLTRVMNKLGGRRRMVSVEDLKTEMEYVHAVVKETVRS 1249
STS+T WALA++IH + +Q+++ + +G +V +EDL ++++Y+ AVVKET+R
Sbjct: 296 STSSTATWALAYLIHEQAVQEKLNEDIRMTIGD-VDLVKIEDL-SKLKYLQAVVKETMRM 353
Query: 1250 RPIVPWGLPRRATRDSELKGMTVREGTQVLVNLYAVLHDERVWKEPNKFMPERFLMSGSS 1429
+PI P +P + D+ L G V GTQ++VNLYA+ H+E +W EP KFMPERFL
Sbjct: 354 KPIAPLAIPHKTANDTTLMGTKVARGTQIMVNLYALHHNEDIWPEPYKFMPERFL----- 408
Query: 1430 GDGEDVT----RMERSFISFGAGRRSCPGME 1510
GE+V+ ME+SF+ FGAG R C GM+
Sbjct: 409 -QGENVSANNKAMEQSFLPFGAGMRICAGMD 438
>sp|Q50LH3.1|C7192_ESCCA RecName: Full=(S)-stylopine synthase 1; Short=STS; AltName:
Full=Cytochrome P450 719A2; Short=EcCYP719A2;
Short=EcCYPB gi|63108256|dbj|BAD98250.1| stylopine
synthase [Eschscholzia californica]
Length = 495
Score = 327 bits (839), Expect = 7e-87
Identities = 176/446 (39%), Positives = 271/446 (60%), Gaps = 2/446 (0%)
Frame = +2
Query: 179 SNLWIIMATVFLLGLLMKLLDQSFLISGSKQQWPPGPKRFPLIGNLYQLSRGGELVHLTL 358
+N WI+ AT L + + L F SK WP GPK P+IGN++ L GG + + L
Sbjct: 10 NNPWILTATATTLLISIFLF---FTRKSSKMVWPAGPKTLPIIGNMHLL--GGTALQVVL 64
Query: 359 AKMAQKHGRIMTVWFGGPEPTIVLSDHELAWEVLVTKVSDYSSRTRNVMSKITSADWNTL 538
+A+ HG +MT+W G P IV+SD E AWEVLV K SDYS+R ++KI SADW T+
Sbjct: 65 HNLAKVHGSVMTIWIGSWRPVIVVSDIERAWEVLVNKSSDYSARDMPDITKIISADWKTI 124
Query: 539 ATSSLGPAWERFRKGLQSTTLHPRIIFSHAQLQEKDIADLTSSLEQEASLNNGIVKPXXX 718
+TS GP W RKGLQ+ L P + + Q QEKD+ + +LE+EA NNGIVKP
Sbjct: 125 STSDSGPHWTNLRKGLQNVALSPHNLAAQFQFQEKDMTKMIQTLEEEARNNNGIVKPLDH 184
Query: 719 XXXXXXXXXXXXCFGPESSMDDLFAEGIYCAIVEAIKLEEKGHLVDVFEFTRYIPGLKPP 898
FG + + +D + + ++ AI E I++ L + F + +Y+P K
Sbjct: 185 MKKATLRLISRLVFGQDFN-NDKYVDDMHLAIEELIRVSGYARLAEAFYYAKYLPSHKKA 243
Query: 899 FKELESLKQRVKVLISSYISTHKPSSSNCYLSFLLSQGFTEDIVIANLFELFMFSVDSTS 1078
+E+E ++RV+ L+S ++S + P +N YL FL SQ + ++++I +FE ++ VDSTS
Sbjct: 244 VREVEEAQRRVQNLVSPFLSLNPP--TNTYLHFLRSQKYDDEVIIFAIFEAYLLGVDSTS 301
Query: 1079 NTIAWALAFVIHHEDIQQRVLTRVMNKLG-GRRRMVSVEDLKTEMEYVHAVVKETVRSRP 1255
T AWALAF+I ++Q+++ + + RR++ VED+ +++Y+ AV+KET+R +P
Sbjct: 302 LTTAWALAFLIREPNVQEKLYQELESFASKNDRRILKVEDI-NKLQYLQAVIKETMRMKP 360
Query: 1256 IVPWGLPRRATRDSELKGMTVREGTQVLVNLYAVLHDERVWKEPNKFMPERFL-MSGSSG 1432
I P +P +A RD+ L G + +GT+V+VN++A+ H++ V+ +P KFMPERF+ +
Sbjct: 361 IAPLAIPHKACRDTSLMGKKIDKGTRVMVNIFALHHNKNVFNDPFKFMPERFMKVDSQDA 420
Query: 1433 DGEDVTRMERSFISFGAGRRSCPGME 1510
+G+ ME+S + F AG R C GME
Sbjct: 421 NGK---AMEQSLLPFSAGMRICAGME 443
>gb|ACO90219.1| stylopine synthase [Eschscholzia californica]
Length = 495
Score = 327 bits (838), Expect = 9e-87
Identities = 177/448 (39%), Positives = 273/448 (60%), Gaps = 4/448 (0%)
Frame = +2
Query: 179 SNLWIIMATVFLLGLLMKLLDQSFLISGSKQQWPPGPKRFPLIGNLYQLSRGGELVHLTL 358
+N WI+ AT L + + L F SK WP GPK P+IGN++ L GG + + L
Sbjct: 10 NNPWILTATATTLLISIFLF---FTRKSSKMVWPAGPKTLPIIGNMHLL--GGTALQVVL 64
Query: 359 AKMAQKHGRIMTVWFGGPEPTIVLSDHELAWEVLVTKVSDYSSRTRNVMSKITSADWNTL 538
+A+ HG +MT+W G P IV+SD E AWEVLV K SDYS+R ++KI SADW T+
Sbjct: 65 HNLAKVHGSVMTIWIGSWRPVIVVSDIERAWEVLVNKSSDYSARDMPDITKIISADWKTI 124
Query: 539 ATSSLGPAWERFRKGLQSTTLHPRIIFSHAQLQEKDIADLTSSLEQEASLNNGIVKPXXX 718
+TS GP W RKGLQ+ L P + + Q QEKD+ + +L++EA NNGIVKP
Sbjct: 125 STSDSGPHWTNLRKGLQNVALSPHNLAAQFQFQEKDMTKMIQTLQEEARNNNGIVKPLDH 184
Query: 719 XXXXXXXXXXXXCFGPESSMDDLFAEGIYCAIVEAIKLEEKGHLVDVFEFTRYIPGLKPP 898
FG + + +D + + ++ AI E I++ L + F + +Y+P K
Sbjct: 185 MKKATLRLISRLVFGQDFN-NDKYVDDMHLAIEELIRVSGYARLAEAFYYAKYLPSHKKA 243
Query: 899 FKELESLKQRVKVLISSYISTHKPSSSNCYLSFLLSQGFTEDIVIANLFELFMFSVDSTS 1078
+E+E ++RV+ L+S ++S + P +N YL FL SQ + ++++I +FE ++ VDSTS
Sbjct: 244 VREVEEAQRRVQNLVSPFLSLNPP--TNTYLHFLRSQKYDDEVIIFAIFEAYLLGVDSTS 301
Query: 1079 NTIAWALAFVIHHEDIQQRV---LTRVMNKLGGRRRMVSVEDLKTEMEYVHAVVKETVRS 1249
T AWALAF+I ++Q+++ L +K+ R+++ VED+ +++Y+ AV+KET+R
Sbjct: 302 LTTAWALAFLIRESNVQEKLYQELESFASKMD--RKILKVEDI-NKLQYLQAVIKETMRM 358
Query: 1250 RPIVPWGLPRRATRDSELKGMTVREGTQVLVNLYAVLHDERVWKEPNKFMPERFL-MSGS 1426
+PI P +P +A RD+ L G + +GT+V+VN+YA+ H++ V+ +P KFMPERF+ +
Sbjct: 359 KPIAPLAIPHKACRDTSLMGKKIDKGTRVMVNIYALHHNKNVFNDPFKFMPERFMKVDSQ 418
Query: 1427 SGDGEDVTRMERSFISFGAGRRSCPGME 1510
+G+ ME+S + F AG R C GME
Sbjct: 419 DANGK---AMEQSLLPFSAGMRICAGME 443
>gb|AFI57927.1| cytochrome P450, partial [Papaver somniferum]
Length = 488
Score = 325 bits (832), Expect = 4e-86
Identities = 178/449 (39%), Positives = 265/449 (59%), Gaps = 2/449 (0%)
Frame = +2
Query: 170 MEQSNLWIIMATVFLLGLLMK-LLDQSFLISGSKQQWPPGPKRFPLIGNLYQLSRGGELV 346
M SNLWI+ +L + L+ IS S +WP GPK P+IGNL+ L GG +
Sbjct: 1 MIMSNLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHIL--GGTAL 58
Query: 347 HLTLAKMAQKHGRIMTVWFGGPEPTIVLSDHELAWEVLVTKVSDYSSRTRNVMSKITSAD 526
H+ L K+A+ +G +MT+W G +P I++SD + AWEVLV K SDYS+R ++KI +A+
Sbjct: 59 HVVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTAN 118
Query: 527 WNTLATSSLGPAWERFRKGLQSTTLHPRIIFSHAQLQEKDIADLTSSLEQEASLNNGIVK 706
W T+++S GP W RKGLQS L P+ + S QE+DI L +L+ EA+LN+G+VK
Sbjct: 119 WRTISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAALNSGMVK 178
Query: 707 PXXXXXXXXXXXXXXXCFGPESSMDDLFAEGIYCAIVEAIKLEEKGHLVDVFEFTRYIPG 886
P +G + DD + E ++ I I++ L +VF + +Y+P
Sbjct: 179 PLDHLKKATVRLISRLIYGQDFD-DDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPS 237
Query: 887 LKPPFKELESLKQRVKVLISSYISTHKPSSSNCYLSFLLSQGFTEDIVIANLFELFMFSV 1066
K E K+RV L+ ++ ++ ++N YL FL SQ + E+++I +FE ++ V
Sbjct: 238 HKRAVTGAEEAKRRVIALVRPFLQSNP--ATNTYLHFLKSQLYPEEVIIFAIFEAYLLGV 295
Query: 1067 DSTSNTIAWALAFVIHHEDIQQRVLTRVMN-KLGGRRRMVSVEDLKTEMEYVHAVVKETV 1243
DSTS+T AWALAF+I +Q+++ + N R M+ VED+ ++ Y+ AVVKET+
Sbjct: 296 DSTSSTTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVN-KLPYLQAVVKETM 354
Query: 1244 RSRPIVPWGLPRRATRDSELKGMTVREGTQVLVNLYAVLHDERVWKEPNKFMPERFLMSG 1423
R +PI P +P +A +D+ L G V +GT+V+VN++A+ H E+VWKEP KFMPERFL
Sbjct: 355 RMKPIAPLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFMPERFLQKH 414
Query: 1424 SSGDGEDVTRMERSFISFGAGRRSCPGME 1510
ME+S + F AG R C GME
Sbjct: 415 DKA-------MEQSLLPFSAGMRICAGME 436
>sp|Q50LH4.1|C7193_ESCCA RecName: Full=(S)-stylopine synthase 2; Short=STS; AltName:
Full=Cytochrome P450 719A3; Short=EcCYP719A3;
Short=EcCYPA gi|63108254|dbj|BAD98249.1| stylopine
synthase [Eschscholzia californica]
Length = 495
Score = 325 bits (832), Expect = 4e-86
Identities = 179/447 (40%), Positives = 264/447 (59%), Gaps = 3/447 (0%)
Frame = +2
Query: 179 SNLWIIMATVFLLGLLMKLLDQSFLISGSKQQWPPGPKRFPLIGNLYQLSRGGELVHLTL 358
+N W++ AT L + + L F WP GPK P+IGN++ L GG + + L
Sbjct: 10 NNPWVLFATSATLLISIFLF---FRRKSPNMAWPEGPKTLPIIGNMHLL--GGTALQVVL 64
Query: 359 AKMAQKHGRIMTVWFGGPEPTIVLSDHELAWEVLVTKVSDYSSRTRNVMSKITSADWNTL 538
+A+ HGR+MT+W G P IV+SD E AWEVLV K SDYS+R ++KI +ADW T+
Sbjct: 65 YNLAKVHGRVMTIWIGSWRPVIVVSDIEQAWEVLVNKSSDYSARDMPDITKIVTADWRTI 124
Query: 539 ATSSLGPAWERFRKGLQSTTLHPRIIFSHAQLQEKDIADLTSSLEQEASLNNGIVKPXXX 718
+TS GP W RKGLQ+ + P + + Q QEKDI + LEQEA NNGIVKP
Sbjct: 125 STSDSGPHWSNLRKGLQNIAISPNNLAAQFQFQEKDIIKMIQILEQEAKDNNGIVKPLDH 184
Query: 719 XXXXXXXXXXXXCFGPESSMDDLFAEGIYCAIVEAIKLEEKGHLVDVFEFTRYIPGLKPP 898
FG + +D + E ++ AI E I++ L + F + +Y+P +
Sbjct: 185 LKKATIRLISRLVFGRDFE-EDKYVEDMHHAIEELIRISGYARLAEAFYYAKYLPSHRKA 243
Query: 899 FKELESLKQRVKVLISSYISTHKPSSSNCYLSFLLSQGFTEDIVIANLFELFMFSVDSTS 1078
+ +E LKQ VK LI ++S + P +N YL FL SQ + E++VI +FE ++ VDSTS
Sbjct: 244 VRYVEELKQIVKNLIRPFLSVNPP--TNTYLHFLRSQNYDEEVVIFAIFETYLLGVDSTS 301
Query: 1079 NTIAWALAFVIHHEDIQQRVLTRVMN-KLGGRRRMVSVEDLKTEMEYVHAVVKETVRSRP 1255
+T AWALA+++ +Q R+ + + R+++ VED+ +++Y+ AV+KET+R +P
Sbjct: 302 STTAWALAYLVREPSVQDRLHQELDHFAKQNDRKILKVEDM-NKLQYLQAVIKETMRMKP 360
Query: 1256 IVPWGLPRRATRDSELKGMTVREGTQVLVNLYAVLHDERVWKEPNKFMPERFLMSGSSGD 1435
I P +P +A +D+ L G + +GT+V+VNLYA+ H++ V+ +P KFMPERFL D
Sbjct: 361 IAPLAIPHKACKDTSLMGNKINKGTRVMVNLYALHHNKNVFNDPFKFMPERFL----KVD 416
Query: 1436 GEDV--TRMERSFISFGAGRRSCPGME 1510
+D ME+S + F AG R C GME
Sbjct: 417 NQDAKGKAMEQSLLPFSAGMRICAGME 443
>gb|ADB89213.1| cheilanthifoline synthase [Papaver somniferum]
Length = 492
Score = 322 bits (825), Expect = 3e-85
Identities = 178/442 (40%), Positives = 264/442 (59%), Gaps = 1/442 (0%)
Frame = +2
Query: 188 WIIMATVFLLGLLMKLLDQSFLISGSKQQWPPGPKRFPLIGNLYQLSRGGELVHLTLAKM 367
W+I V + L KLL S S +WP GPK P+IGNL+QL GGE H+ LA +
Sbjct: 6 WLITCGVVVAFALAKLLFGK-KSSMSTMEWPSGPKTLPIIGNLHQL--GGEAFHVCLANL 62
Query: 368 AQKHGRIMTVWFGGPEPTIVLSDHELAWEVLVTKVSDYSSRTRNVMSKITSADWNTLATS 547
A+ +G + T+W G P IV+SD + AWEVLV K SDYS+R ++KI SA+W ++
Sbjct: 63 AKVYGGVFTIWVGSWRPFIVISDVDKAWEVLVNKSSDYSARDMPDITKIISANWKNISHG 122
Query: 548 SLGPAWERFRKGLQSTTLHPRIIFSHAQLQEKDIADLTSSLEQEASLNNGIVKPXXXXXX 727
GP W RKGLQ L P + S LQE+D+ +L S++++AS NGI+KP
Sbjct: 123 DSGPFWHNLRKGLQGVALTPFNVASQYHLQERDMQNLIKSMKKKASQKNGILKPLDYVKE 182
Query: 728 XXXXXXXXXCFGPESSMDDLFAEGIYCAIVEAIKLEEKGHLVDVFEFTRYIPGLKPPFKE 907
FG + +D+ F G++ A+ E + + L D F+F +P K +
Sbjct: 183 ETVRLLSRLIFG-QDFVDEDFVVGMHQALDELVSISGYASLADAFKFCENLPSHKKTVRA 241
Query: 908 LESLKQRVKVLISSYISTHKPSSSNCYLSFLLSQGFTEDIVIANLFELFMFSVDSTSNTI 1087
+ ++K R LI +I ++ P +N YL FLLSQ F+ED++I+ + E++ VDST++T
Sbjct: 242 VHAIKIRFDNLIRPHIVSNPP--TNTYLHFLLSQDFSEDVIISAILEVYDLGVDSTASTT 299
Query: 1088 AWALAFVIHHEDIQQRVLTRVMNKLGGRRRMVSVEDLKTEMEYVHAVVKETVRSRPIVPW 1267
WAL F++ + IQ++ L R +N + G ++ V VEDL ++ Y+ AV+KET+R +PI P
Sbjct: 300 VWALTFLVREQKIQEK-LYREINNVTGGKKPVKVEDL-NKLPYLQAVMKETMRMKPIAPM 357
Query: 1268 GLPRRATRDSELKGMTVREGTQVLVNLYAVLHDERVWKEPNKFMPERFLM-SGSSGDGED 1444
+P +A++D+ L G + +G V+VNLYA+ H+ V+ EP KFMPERFL + S G D
Sbjct: 358 AIPHKASKDTSLMGKKINKGAVVMVNLYAIHHNPAVFPEPYKFMPERFLKDANSDGSLGD 417
Query: 1445 VTRMERSFISFGAGRRSCPGME 1510
+ +ME S ++F AG R C GME
Sbjct: 418 IKKMESSLLAFSAGMRICAGME 439
>gb|AGL76711.1| (S)-canadine synthase, partial [Coptis chinensis]
Length = 491
Score = 320 bits (819), Expect = 1e-84
Identities = 175/449 (38%), Positives = 274/449 (61%), Gaps = 2/449 (0%)
Frame = +2
Query: 170 MEQSNLWII--MATVFLLGLLMKLLDQSFLISGSKQQWPPGPKRFPLIGNLYQLSRGGEL 343
ME S L + +A VF ++++L S + K WP GP++ P+IGNL+QL G ++
Sbjct: 1 MEMSPLLVCATVAIVFATTTIIRILFSSSSLPQMK--WPSGPRKLPIIGNLHQL--GDDV 56
Query: 344 VHLTLAKMAQKHGRIMTVWFGGPEPTIVLSDHELAWEVLVTKVSDYSSRTRNVMSKITSA 523
+H+ LAK+A+ HG +MT+W G P IV+SD E AWEVLV K +DY +R ++KI SA
Sbjct: 57 LHVALAKLAKVHGSMMTIWIGSWRPVIVISDLEKAWEVLVNKSADYGARDMPEITKIASA 116
Query: 524 DWNTLATSSLGPAWERFRKGLQSTTLHPRIIFSHAQLQEKDIADLTSSLEQEASLNNGIV 703
W+T++TS GP W+ RKGLQS + P + + Q QE+ + L ++ EA+ NNGIV
Sbjct: 117 SWHTISTSDAGPFWQNVRKGLQSGAMGPFNVAAQNQHQERGMKRLIKAMSDEAANNNGIV 176
Query: 704 KPXXXXXXXXXXXXXXXCFGPESSMDDLFAEGIYCAIVEAIKLEEKGHLVDVFEFTRYIP 883
KP FG ++ D+ F E ++ I + I++ L + F + +Y+P
Sbjct: 177 KPLDHIKKNTVRLLTRLIFG-QNFDDNKFIESMHYEIEDIIRISGYARLAEAFYYAKYLP 235
Query: 884 GLKPPFKELESLKQRVKVLISSYISTHKPSSSNCYLSFLLSQGFTEDIVIANLFELFMFS 1063
K +E +K RV+ L+ +S++ P +N YL FLLSQ F E+++I +FEL++
Sbjct: 236 SHKKAEREAFLVKCRVQELVRPLLSSNPP--TNSYLYFLLSQNFEEEVIIFCIFELYLLG 293
Query: 1064 VDSTSNTIAWALAFVIHHEDIQQRVLTRVMNKLGGRRRMVSVEDLKTEMEYVHAVVKETV 1243
VDSTS+T WALA++I + Q+++ + LG +V +ED+ +++Y+ VVKET+
Sbjct: 294 VDSTSSTTTWALAYLIREQGAQEKLYQDIRMTLGD-VDLVKIEDV-NKLKYLQGVVKETM 351
Query: 1244 RSRPIVPWGLPRRATRDSELKGMTVREGTQVLVNLYAVLHDERVWKEPNKFMPERFLMSG 1423
R +PI P +P + +++ L G V +GT+++VNLYA+ H++ +W +P KFMPERFL G
Sbjct: 352 RMKPIAPLAIPHKTAKETTLMGTKVAKGTRIMVNLYALHHNQNIWPDPYKFMPERFL-EG 410
Query: 1424 SSGDGEDVTRMERSFISFGAGRRSCPGME 1510
++G + ME+SF+ F AG R C GM+
Sbjct: 411 ATGTAYN-KAMEQSFLPFSAGMRICAGMD 438
>sp|Q948Y1.1|C719A_COPJA RecName: Full=(S)-canadine synthase; AltName:
Full=(S)-tetrahydrocolumbamine oxidase
(methylenedioxy-bridge-forming); AltName: Full=Cytochrome
P450 719A1 gi|15822820|dbj|BAB68769.1| methylenedioxy
bridge-forming enzyme [Coptis japonica]
Length = 491
Score = 319 bits (818), Expect = 2e-84
Identities = 173/448 (38%), Positives = 270/448 (60%)
Frame = +2
Query: 167 EMEQSNLWIIMATVFLLGLLMKLLDQSFLISGSKQQWPPGPKRFPLIGNLYQLSRGGELV 346
EM + +A VF ++++L S + K WP GP++ P+IGNL+QL G +++
Sbjct: 2 EMNPLLVCATVAIVFATTTIIRILFSSSSLPQMK--WPSGPRKLPIIGNLHQL--GDDVL 57
Query: 347 HLTLAKMAQKHGRIMTVWFGGPEPTIVLSDHELAWEVLVTKVSDYSSRTRNVMSKITSAD 526
H+ LAK+A+ HG +MT+W G P IV+SD E AWEVLV K +DY +R ++KI SA
Sbjct: 58 HVALAKLAKVHGSVMTIWIGSWRPVIVISDIEKAWEVLVNKSADYGARDMPEITKIASAS 117
Query: 527 WNTLATSSLGPAWERFRKGLQSTTLHPRIIFSHAQLQEKDIADLTSSLEQEASLNNGIVK 706
W+T++TS G W+ RKGLQS + P + + Q QE+D+ L ++ EA+ NNGIVK
Sbjct: 118 WHTISTSDAGSFWQNVRKGLQSGAMGPLNVAAQNQYQERDMKRLIKAMSDEAANNNGIVK 177
Query: 707 PXXXXXXXXXXXXXXXCFGPESSMDDLFAEGIYCAIVEAIKLEEKGHLVDVFEFTRYIPG 886
P FG ++ D+ F E ++ I + I++ L + F + +Y+P
Sbjct: 178 PLDHIKKNTVRLLTRLIFG-QAFDDNKFIESMHYEIEDIIRISGYARLAEAFYYAKYLPS 236
Query: 887 LKPPFKELESLKQRVKVLISSYISTHKPSSSNCYLSFLLSQGFTEDIVIANLFELFMFSV 1066
K +E +K RV+ L+ +S+ P +N YL FLLSQ F E+++I +FEL++ V
Sbjct: 237 HKKAEREAFLVKCRVEELVRPLLSSKPP--TNSYLYFLLSQNFEEEVIIFCIFELYLLGV 294
Query: 1067 DSTSNTIAWALAFVIHHEDIQQRVLTRVMNKLGGRRRMVSVEDLKTEMEYVHAVVKETVR 1246
DSTS+T WALA++I + Q+++ + LG +V +ED+ +++Y+ VVKET+R
Sbjct: 295 DSTSSTTTWALAYLIREQGAQEKLYQDIRMTLGD-VDLVKIEDV-NKLKYLQGVVKETMR 352
Query: 1247 SRPIVPWGLPRRATRDSELKGMTVREGTQVLVNLYAVLHDERVWKEPNKFMPERFLMSGS 1426
+PI P +P + +++ L G V +GT+++VNLYA+ H++ +W +P KFMPERFL G
Sbjct: 353 MKPIAPLAIPHKTAKETTLMGTKVAKGTRIMVNLYALHHNQNIWPDPYKFMPERFL-EGE 411
Query: 1427 SGDGEDVTRMERSFISFGAGRRSCPGME 1510
+G + ME+SF+ F AG R C GM+
Sbjct: 412 TGTAYN-KAMEQSFLPFSAGMRICAGMD 438
>dbj|BAG75115.1| cytochrome P450 [Eschscholzia californica]
Length = 494
Score = 318 bits (815), Expect = 4e-84
Identities = 175/445 (39%), Positives = 258/445 (57%), Gaps = 1/445 (0%)
Frame = +2
Query: 179 SNLWIIMATVFLLGLLMKLLDQSFLISGSKQQWPPGPKRFPLIGNLYQLSRGGELVHLTL 358
+N W++ AT L + M L F SK WP GPK P+IGN++ L G + + + L
Sbjct: 10 NNPWVVTATSATLLISMFLF---FTRKSSKMVWPKGPKTLPIIGNMHLLG-GSKALQVIL 65
Query: 359 AKMAQKHGRIMTVWFGGPEPTIVLSDHELAWEVLVTKVSDYSSRTRNVMSKITSADWNTL 538
+++ HG +MT+W G P IV+S+ E WEVLV K SDYS R + K SAD+ T+
Sbjct: 66 HNLSKVHGSVMTIWIGRWRPVIVVSNIERVWEVLVNKSSDYSGRYVPDVIKFVSADFRTI 125
Query: 539 ATSSLGPAWERFRKGLQSTTLHPRIIFSHAQLQEKDIADLTSSLEQEASLNNGIVKPXXX 718
+TS GP W RKGLQ+ L P + + Q QEKDI +T LE+EA N GIVKP
Sbjct: 126 STSDSGPHWTNLRKGLQNVALSPNSLAAQFQFQEKDIIKMTDILEREARNNKGIVKPLDH 185
Query: 719 XXXXXXXXXXXXCFGPESSMDDLFAEGIYCAIVEAIKLEEKGHLVDVFEFTRYIPGLKPP 898
FGP + DD + E ++ I E I++ L + F + +Y+P +
Sbjct: 186 LKKATVRLISRLVFGPNFN-DDQYVEDMHNTIDELIQMSSYAQLAEAFYYAKYLPSHRKA 244
Query: 899 FKELESLKQRVKVLISSYISTHKPSSSNCYLSFLLSQGFTEDIVIANLFELFMFSVDSTS 1078
+ E KQ VK LI YIS P N YL FL SQ + E++VI +FE ++ VDSTS
Sbjct: 245 VRHFEQTKQIVKKLIRPYISVSPPP--NTYLHFLQSQNYDEEVVIFAIFEAYLLGVDSTS 302
Query: 1079 NTIAWALAFVIHHEDIQQRVLTRVMN-KLGGRRRMVSVEDLKTEMEYVHAVVKETVRSRP 1255
+T WALAF+I ++Q+++ + N R ++ VED+ +++Y+ AV KET+R +P
Sbjct: 303 STTTWALAFLIREPNVQEKLYQELKNFAEQNDREIMKVEDI-NKLQYLQAVTKETMRMKP 361
Query: 1256 IVPWGLPRRATRDSELKGMTVREGTQVLVNLYAVLHDERVWKEPNKFMPERFLMSGSSGD 1435
+ P +P +A R++ L GM + +GT+V+VN++++ H+E V+ +P FMPERFL D
Sbjct: 362 VAPLAIPHKACRETSLMGMPIDKGTKVMVNIHSLHHNENVFSDPFTFMPERFL----KVD 417
Query: 1436 GEDVTRMERSFISFGAGRRSCPGME 1510
++V ME+S++ F AG R C G+E
Sbjct: 418 NQNVKAMEQSYLPFSAGMRICAGIE 442
>dbj|BAG75116.1| cytochrome P450 [Eschscholzia californica]
Length = 495
Score = 317 bits (813), Expect = 7e-84
Identities = 175/444 (39%), Positives = 256/444 (57%)
Frame = +2
Query: 179 SNLWIIMATVFLLGLLMKLLDQSFLISGSKQQWPPGPKRFPLIGNLYQLSRGGELVHLTL 358
+N WI+ AT L + M L F SK WP GPK P+IGN++ L GG + + L
Sbjct: 10 NNPWILTATATTLLISMFLF---FTRKSSKMVWPQGPKTLPIIGNMHLL--GGTALQVVL 64
Query: 359 AKMAQKHGRIMTVWFGGPEPTIVLSDHELAWEVLVTKVSDYSSRTRNVMSKITSADWNTL 538
+A+ HG +MT+W G P IV+SD E AWEVLV K SDYS+R + K +AD T+
Sbjct: 65 HNLAKVHGSVMTIWIGSWRPVIVVSDIERAWEVLVNKSSDYSARELPDIIKYNTADCRTI 124
Query: 539 ATSSLGPAWERFRKGLQSTTLHPRIIFSHAQLQEKDIADLTSSLEQEASLNNGIVKPXXX 718
AT GP W RKGLQ+ L P + + Q QEKD+ + LEQEA NGIVKP
Sbjct: 125 ATCDSGPHWSNLRKGLQNVALSPNNLAAQFQFQEKDVIKMIDILEQEAINKNGIVKPLDH 184
Query: 719 XXXXXXXXXXXXCFGPESSMDDLFAEGIYCAIVEAIKLEEKGHLVDVFEFTRYIPGLKPP 898
FG + + DD + E ++ AI E I++ L + F + +Y+P K
Sbjct: 185 LKKATIRLISRLVFGQDFN-DDKYVEDLHQAIEELIRMSGYAQLAEAFYYAKYLPSHKKA 243
Query: 899 FKELESLKQRVKVLISSYISTHKPSSSNCYLSFLLSQGFTEDIVIANLFELFMFSVDSTS 1078
+ E KQ V L+ ++S + P++S YL FL SQ + E++VI +FE ++ VDSTS
Sbjct: 244 IRHAELTKQIVTNLVRPFLSLNPPTNS--YLHFLQSQKYDEEMVIFAIFETYLLGVDSTS 301
Query: 1079 NTIAWALAFVIHHEDIQQRVLTRVMNKLGGRRRMVSVEDLKTEMEYVHAVVKETVRSRPI 1258
+T AWALA+++ ++Q R+ + N R + ++ +++Y+ AV KET+R +PI
Sbjct: 302 STTAWALAYLVREPNVQDRLYNELNNYANYNDRKILKVEVINKLQYLQAVTKETMRMKPI 361
Query: 1259 VPWGLPRRATRDSELKGMTVREGTQVLVNLYAVLHDERVWKEPNKFMPERFLMSGSSGDG 1438
P +P +A RD+ L G + +GT+V+VNL+A+ H+E V+ +P KFMPERFL + +
Sbjct: 362 APLAIPHKACRDTSLMGTKIDKGTKVMVNLHALHHNENVFTDPFKFMPERFLK--VNNED 419
Query: 1439 EDVTRMERSFISFGAGRRSCPGME 1510
++ ME+S + F AG R C GME
Sbjct: 420 VNMKAMEQSLLPFSAGMRICAGME 443
>gb|AFB74615.1| cytochrome P450 [Papaver somniferum]
Length = 486
Score = 317 bits (811), Expect = 1e-83
Identities = 176/449 (39%), Positives = 264/449 (58%), Gaps = 2/449 (0%)
Frame = +2
Query: 170 MEQSNLWIIMATVFLLGLLMK-LLDQSFLISGSKQQWPPGPKRFPLIGNLYQLSRGGELV 346
M SNLWI+ +L + L+ IS S +WP GPK P+IGNL+ L GG +
Sbjct: 1 MIMSNLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHIL--GGTAL 58
Query: 347 HLTLAKMAQKHGRIMTVWFGGPEPTIVLSDHELAWEVLVTKVSDYSSRTRNVMSKITSAD 526
H+ L K+A+ +G +MT+W G +P I++SD + AWEVLV K SDYS+R ++KI +A+
Sbjct: 59 HVVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTAN 118
Query: 527 WNTLATSSLGPAWERFRKGLQSTTLHPRIIFSHAQLQEKDIADLTSSLEQEASLNNGIVK 706
W T+++S GP W RKGLQS L P+ + S QE+DI L +L+ EA+ +G+VK
Sbjct: 119 WRTISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAA--SGMVK 176
Query: 707 PXXXXXXXXXXXXXXXCFGPESSMDDLFAEGIYCAIVEAIKLEEKGHLVDVFEFTRYIPG 886
P +G + DD + E ++ I I++ L +VF + +Y+PG
Sbjct: 177 PLDHLKKATVRLISRLIYGQDFD-DDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPG 235
Query: 887 LKPPFKELESLKQRVKVLISSYISTHKPSSSNCYLSFLLSQGFTEDIVIANLFELFMFSV 1066
K E K+RV L+ ++ ++ ++N YL FL SQ + E+++I +FE ++ V
Sbjct: 236 HKRAVTGAEEAKRRVIALVRPFLQSNP--ATNTYLHFLKSQLYPEEVIIFAIFEAYLLGV 293
Query: 1067 DSTSNTIAWALAFVIHHEDIQQRVLTRVMN-KLGGRRRMVSVEDLKTEMEYVHAVVKETV 1243
DSTS+T AWALAF+I +Q+++ + N R M+ VED+ ++ Y+ AVVKET+
Sbjct: 294 DSTSSTTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVN-KLPYLQAVVKETM 352
Query: 1244 RSRPIVPWGLPRRATRDSELKGMTVREGTQVLVNLYAVLHDERVWKEPNKFMPERFLMSG 1423
R +PI P +P +A +D+ L G V +GT+V+VN++A+ H E+VWKEP KF+PERFL
Sbjct: 353 RMKPIAPLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQKH 412
Query: 1424 SSGDGEDVTRMERSFISFGAGRRSCPGME 1510
ME+S + F AG R C GME
Sbjct: 413 DKA-------MEQSLLPFSAGMRICAGME 434
>gb|AGC29953.1| CYP719A23 [Sinopodophyllum hexandrum]
Length = 489
Score = 306 bits (784), Expect = 2e-80
Identities = 173/448 (38%), Positives = 266/448 (59%)
Frame = +2
Query: 167 EMEQSNLWIIMATVFLLGLLMKLLDQSFLISGSKQQWPPGPKRFPLIGNLYQLSRGGELV 346
EME S L M++ +L L M L+ S S +WPPGPK P+IGNL+QL GG+ +
Sbjct: 2 EMEMSVL--AMSSTLILALAMALIFLFKAKSSSAIKWPPGPKTLPIIGNLHQL--GGDEL 57
Query: 347 HLTLAKMAQKHGRIMTVWFGGPEPTIVLSDHELAWEVLVTKVSDYSSRTRNVMSKITSAD 526
H+ LAK+A+ HG IMT+W +P IV+SD WEVLV+K SDY++R +SKI SA
Sbjct: 58 HIVLAKLARVHGAIMTIWMA-KKPVIVVSDVNSVWEVLVSKSSDYAARDAAEISKIVSAS 116
Query: 527 WNTLATSSLGPAWERFRKGLQSTTLHPRIIFSHAQLQEKDIADLTSSLEQEASLNNGIVK 706
+++ TS GP W+ R+GL L P I + +Q++D+ + ++Q+A+ N GI+K
Sbjct: 117 SHSINTSDSGPYWQTLRRGLTHGPLGPLNISAQIPIQQRDMQRVIREMQQDAAANGGIIK 176
Query: 707 PXXXXXXXXXXXXXXXCFGPESSMDDLFAEGIYCAIVEAIKLEEKGHLVDVFEFTRYIPG 886
P FG ++ +D + + ++ + + + L F F +++P
Sbjct: 177 PLDHLKRSSTRLVSRLIFG-DTFDNDPYNDSMHEVVQDLNRFGGIALLEQAFSFAKHLPS 235
Query: 887 LKPPFKELESLKQRVKVLISSYISTHKPSSSNCYLSFLLSQGFTEDIVIANLFELFMFSV 1066
K KE K+++ L+ +++ P SN YL FL SQ ++E+I+IA +FEL++ ++
Sbjct: 236 YKRGVKEFHIHKRKIDDLVRPVVASANP-PSNSYLGFLQSQNYSEEIIIACIFELYLLAM 294
Query: 1067 DSTSNTIAWALAFVIHHEDIQQRVLTRVMNKLGGRRRMVSVEDLKTEMEYVHAVVKETVR 1246
DS+++T WALAF+I + +Q+++ + +G +V EDL ++M Y+ AVVKET+R
Sbjct: 295 DSSASTATWALAFMIRDQQVQEKLYQDIKRVIGDGVDLVKAEDL-SKMHYLQAVVKETMR 353
Query: 1247 SRPIVPWGLPRRATRDSELKGMTVREGTQVLVNLYAVLHDERVWKEPNKFMPERFLMSGS 1426
+PI P +P + D+ + G V +GT V+VNLYA+ HDE VW +P FMPERFL
Sbjct: 354 MKPIAPLAIPHKTAIDTTVMGTKVPKGTCVMVNLYALHHDESVWAKPYTFMPERFL---Q 410
Query: 1427 SGDGEDVTRMERSFISFGAGRRSCPGME 1510
DG+ VT E++F+ FGAG R C GME
Sbjct: 411 GEDGKSVT--EQAFLPFGAGMRICGGME 436
>dbj|BAG75114.1| cytochrome P450 [Eschscholzia californica]
Length = 495
Score = 306 bits (783), Expect = 2e-80
Identities = 171/448 (38%), Positives = 259/448 (57%), Gaps = 4/448 (0%)
Frame = +2
Query: 179 SNLWIIMATVFLLGLLMKLLDQSFLI---SGSKQQWPPGPKRFPLIGNLYQLSRGGELVH 349
+N W++ AT LL FL S +WP GPK P+IGN++ L G + +
Sbjct: 10 NNPWVLTAT------FTTLLISIFLFVTRKTSNTEWPNGPKTLPIIGNMHLLG-GTKALQ 62
Query: 350 LTLAKMAQKHGRIMTVWFGGPEPTIVLSDHELAWEVLVTKVSDYSSRTRNVMSKITSADW 529
+ L +A+ +G +MT+W G P I++SD E AWEVLV K SDYS+R + K +A++
Sbjct: 63 VILHNLAKVYGGVMTIWIGSWRPVIIVSDIERAWEVLVNKSSDYSARELPEIIKYNAANF 122
Query: 530 NTLATSSLGPAWERFRKGLQSTTLHPRIIFSHAQLQEKDIADLTSSLEQEASLNNGIVKP 709
T+AT GP W RKGLQ+ L P + + Q QEKDI + +LE EA NNGIV+P
Sbjct: 123 RTIATCDSGPHWSNLRKGLQNVALSPHNLAAQFQFQEKDITKMIQNLEVEAKNNNGIVQP 182
Query: 710 XXXXXXXXXXXXXXXCFGPESSMDDLFAEGIYCAIVEAIKLEEKGHLVDVFEFTRYIPGL 889
FG + +D + E ++ I E I++ L + F + RY+P
Sbjct: 183 LDHLKKATIRLISRLIFGQDFD-EDTYVEKLHHTIDELIRMSGYAQLAEAFYYARYLPNH 241
Query: 890 KPPFKELESLKQRVKVLISSYISTHKPSSSNCYLSFLLSQGFTEDIVIANLFELFMFSVD 1069
K KQ V L+ ++S + P++S YL FL SQ + E+++I ++FE+++ VD
Sbjct: 242 KKAVNHAAKTKQIVTHLMRPFLSLNPPTNS--YLHFLQSQNYDEELIIFSIFEVYLLGVD 299
Query: 1070 STSNTIAWALAFVIHHEDIQQRVLTRVMN-KLGGRRRMVSVEDLKTEMEYVHAVVKETVR 1246
STS+T AWALA+++ ++Q+ + + N R+++ VED+ +++Y+ AV KET+R
Sbjct: 300 STSSTTAWALAYLVREPNVQETLYQELDNFAKQNDRKILKVEDIN-KLQYLQAVTKETMR 358
Query: 1247 SRPIVPWGLPRRATRDSELKGMTVREGTQVLVNLYAVLHDERVWKEPNKFMPERFLMSGS 1426
+PI P +P +A+RD+ L G V +GT+V+VNL+A+ H+E V+ +P KFMPERFL
Sbjct: 359 MKPIAPLAIPHKASRDTTLMGKKVEKGTKVMVNLHALHHNENVFNDPYKFMPERFL---K 415
Query: 1427 SGDGEDVTRMERSFISFGAGRRSCPGME 1510
S G ME+S++ F AG R C GME
Sbjct: 416 SYQGAKAKAMEQSYLPFSAGMRICGGME 443
>sp|B1NF18.1|C719B_PAPSO RecName: Full=Salutaridine synthase; AltName: Full=Cytochrome P450
719B1 gi|148841090|gb|ABR14720.1| salutaridine synthase
[Papaver somniferum]
Length = 505
Score = 305 bits (782), Expect = 3e-80
Identities = 173/450 (38%), Positives = 269/450 (59%), Gaps = 3/450 (0%)
Frame = +2
Query: 170 MEQSNLWIIMATVFLLGLLMKLLDQ--SFLISGSKQQWPPGPKRFPLIGNLYQLSRGGEL 343
+E ++ W+I TV ++ L+K + SF S + +WP GPK P+IGNL+QL GG
Sbjct: 6 IEGNDFWMIACTVIIVFALVKFMFSKISFYQSANTTEWPAGPKTLPIIGNLHQLG-GGVP 64
Query: 344 VHLTLAKMAQKHGRIMTVWFGGPEPTIVLSDHELAWEVLVTKVSDYSSRTRNVMSKITSA 523
+ + LA +A+ +G T+W G P IV+SD + A EVLV K +DYS+R + KI +A
Sbjct: 65 LQVALANLAKVYGGAFTIWIGSWVPMIVISDIDNAREVLVNKSADYSARDVPDILKIITA 124
Query: 524 DWNTLATSSLGPAWERFRKGLQSTTLHPRIIFSHAQLQEKDIADLTSSLEQEASLNNGIV 703
+ +A GP W +KGLQS ++P + S ++LQEKD+ +L S+++ AS +NGI+
Sbjct: 125 NGKNIADCDSGPFWHNLKKGLQSC-INPSNVMSLSRLQEKDMQNLIKSMQERASQHNGII 183
Query: 704 KPXXXXXXXXXXXXXXXCFGPESSMDDLFAEGIYCAIVEAIKLEEKGHLVDVFEFTRYIP 883
KP FG + S +DL G+ A+ E +++ L D F+ +Y+P
Sbjct: 184 KPLDHAKEASMRLLSRVIFGHDFSNEDLVI-GVKDALDEMVRISGLASLADAFKIAKYLP 242
Query: 884 GLKPPFKELESLKQRVKVLISSYISTHKPSSSNCYLSFLLSQGFTEDIVIANLFELFMFS 1063
+ +++ + + RV LI +I + P++S +L FL SQ ++++I+ + + E+F
Sbjct: 243 SQRKNIRDMYATRDRVYNLIQPHIVPNLPANS--FLYFLTSQDYSDEIIYSMVLEIFGLG 300
Query: 1064 VDSTSNTIAWALAFVIHHEDIQQRVLTRVMNKLGGRRRMVSVEDLKTEMEYVHAVVKETV 1243
VDST+ T WAL+F++ ++IQ+++ + N+ GG+R V V DLK E+ Y+ AV+KET+
Sbjct: 301 VDSTAATAVWALSFLVGEQEIQEKLYREINNRTGGQRP-VKVVDLK-ELPYLQAVMKETL 358
Query: 1244 RSRPIVPWGLPRRATRDSELKGMTVREGTQVLVNLYAVLHDERVWKEPNKFMPERFLMS- 1420
R +PI P +P A +D+ KG + +GT+V+VNLYA+ HD V+ P KFMPERFL
Sbjct: 359 RMKPIAPLAVPHVAAKDTTFKGRRIVKGTKVMVNLYAIHHDPNVFPAPYKFMPERFLKDV 418
Query: 1421 GSSGDGEDVTRMERSFISFGAGRRSCPGME 1510
S G D+ ME S I FGAG R C G+E
Sbjct: 419 NSDGRFGDINTMESSLIPFGAGMRICGGVE 448