BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Cocculus23_contig00002885
         (1332 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gb|AHF65153.1| stylopine synthase, partial [synthetic construct]      342   2e-91
gb|ADB89214.1| stylopine synthase [Papaver somniferum]                342   2e-91
gb|AAU20771.1| (S)-canadine synthase [Thalictrum flavum subsp. g...   339   2e-90
sp|B5UAQ8.1|C7195_ESCCA RecName: Full=Cheilanthifoline synthase;...   336   2e-89
sp|B1NF19.1|C719D_ARGME RecName: Full=(S)-stylopine synthase; Sh...   336   2e-89
sp|Q50LH4.1|C7193_ESCCA RecName: Full=(S)-stylopine synthase 2; ...   330   1e-87
gb|AGL76711.1| (S)-canadine synthase, partial [Coptis chinensis]      329   1e-87
sp|Q948Y1.1|C719A_COPJA RecName: Full=(S)-canadine synthase; Alt...   329   1e-87
gb|ACO90219.1| stylopine synthase [Eschscholzia californica]          329   1e-87
sp|Q50LH3.1|C7192_ESCCA RecName: Full=(S)-stylopine synthase 1; ...   328   3e-87
sp|B1NF20.1|C719E_ARGME RecName: Full=Cheilanthifoline synthase;...   322   2e-85
gb|AFI57927.1| cytochrome P450, partial [Papaver somniferum]          320   9e-85
dbj|BAF98470.1| cytochrome P450 [Coptis japonica var. dissecta]       318   3e-84
gb|ADB89213.1| cheilanthifoline synthase [Papaver somniferum]         315   2e-83
gb|AFB74615.1| cytochrome P450 [Papaver somniferum]                   315   4e-83
dbj|BAG75116.1| cytochrome P450 [Eschscholzia californica]            314   5e-83
dbj|BAG75115.1| cytochrome P450 [Eschscholzia californica]            307   8e-81
dbj|BAG75114.1| cytochrome P450 [Eschscholzia californica]            305   3e-80
gb|AGC29953.1| CYP719A23 [Sinopodophyllum hexandrum]                  303   1e-79
dbj|BAF98471.1| cytochrome P450 [Coptis japonica var. dissecta]       300   1e-78

>gb|AHF65153.1| stylopine synthase, partial [synthetic construct]
          Length = 511

 Score =  342 bits (877), Expect = 2e-91
 Identities = 180/418 (43%), Positives = 260/418 (62%), Gaps = 1/418 (0%)
 Frame = +1

Query: 82   WPPGPMRFPLIGNLHQLRRGGQLVHLTLSKMAEKHGRIMTVWFGGPEPTIVVSDHEVAWE 261
            WP GP   P+IGN+H L  GG  + + L  +A+ HG +MT+W G   P IVVSD + AWE
Sbjct: 53   WPTGPKTLPIIGNMHVL--GGTALQVVLHNLAKIHGNVMTIWIGSWRPVIVVSDIDRAWE 110

Query: 262  VLVTKVNDYSARQLPVMSKITSADWHTLATSSLGPTWERFRKGLQSTTLHPRIISSHSQL 441
            VLV K +DYSAR +P ++KI SADW T++TS  GP W   RKGLQ+  L P  +++ SQ 
Sbjct: 111  VLVNKSSDYSARDMPEITKIISADWKTISTSDSGPGWSNLRKGLQNVALSPHNLAAQSQF 170

Query: 442  QEKDVADLISSFEQEASLNNGIVKPVPKLRKLAIRVAGRLCFGPESTMDDQFAEGIDWAI 621
            QEKD+  +I S ++EA+ NNGIVKP+  L+K  +R+  RL FG +   DD++ + +  AI
Sbjct: 171  QEKDITKMIQSLKKEAASNNGIVKPIDHLKKATLRLISRLIFGQDFD-DDKYVDDMHHAI 229

Query: 622  VEAIRLGDQARLVDMFEFTRYIPGLKPPYKELESLNQRVKEHISSYLSTHKPSSSSNCYL 801
             E IR+   A+L + F + +Y+P  K   +++E  NQRVK+ +  +LS + P   +N YL
Sbjct: 230  EELIRVSGYAQLAEAFYYAKYLPSHKKAVRDVEEANQRVKKLVRPFLSLNPP---TNTYL 286

Query: 802  SFLLSQGFTEDILLANLFELFMFSVDSLAGTIAWALAFMIHHEDVQQRVLKQVMNKLG-G 978
             FL SQ + E++++  +FE ++  VDS + T AWALAF+I    VQ ++ +++ N     
Sbjct: 287  HFLNSQKYDEEVIIFAIFEAYLLGVDSTSLTTAWALAFLIREPVVQDKLYQELKNLTAKN 346

Query: 979  TRKMVSVEDLTSTEMEYVHAVVKETXXXXXXXXXXXXXXXXXDTELKGMTVKAGTLVLVN 1158
              ++V VEDL   +++Y+ AV+KET                 DT LKG  +  GT V+VN
Sbjct: 347  DCEIVKVEDL--NKLQYLQAVLKETMRMKPIAPLAIPHKACRDTSLKGNKIDQGTQVMVN 404

Query: 1159 LYAVLHDERVWKEPEKFIPERFLMSASSGDAEEVKRMERSFVPFAAGRRSCPAMELAK 1332
            +YA+ H+E+VWKEP KF+PERFL +    D    K ME+S +PF+AG R C  MEL K
Sbjct: 405  IYALHHNEKVWKEPFKFMPERFLQTQ---DVVNGKGMEQSLLPFSAGMRICAGMELGK 459


>gb|ADB89214.1| stylopine synthase [Papaver somniferum]
          Length = 494

 Score =  342 bits (877), Expect = 2e-91
 Identities = 180/418 (43%), Positives = 260/418 (62%), Gaps = 1/418 (0%)
 Frame = +1

Query: 82   WPPGPMRFPLIGNLHQLRRGGQLVHLTLSKMAEKHGRIMTVWFGGPEPTIVVSDHEVAWE 261
            WP GP   P+IGN+H L  GG  + + L  +A+ HG +MT+W G   P IVVSD + AWE
Sbjct: 39   WPTGPKTLPIIGNMHVL--GGTALQVVLHNLAKIHGNVMTIWIGSWRPVIVVSDIDRAWE 96

Query: 262  VLVTKVNDYSARQLPVMSKITSADWHTLATSSLGPTWERFRKGLQSTTLHPRIISSHSQL 441
            VLV K +DYSAR +P ++KI SADW T++TS  GP W   RKGLQ+  L P  +++ SQ 
Sbjct: 97   VLVNKSSDYSARDMPEITKIISADWKTISTSDSGPGWSNLRKGLQNVALSPHNLAAQSQF 156

Query: 442  QEKDVADLISSFEQEASLNNGIVKPVPKLRKLAIRVAGRLCFGPESTMDDQFAEGIDWAI 621
            QEKD+  +I S ++EA+ NNGIVKP+  L+K  +R+  RL FG +   DD++ + +  AI
Sbjct: 157  QEKDITKMIQSLKKEAASNNGIVKPIDHLKKATLRLISRLIFGQDFD-DDKYVDDMHHAI 215

Query: 622  VEAIRLGDQARLVDMFEFTRYIPGLKPPYKELESLNQRVKEHISSYLSTHKPSSSSNCYL 801
             E IR+   A+L + F + +Y+P  K   +++E  NQRVK+ +  +LS + P   +N YL
Sbjct: 216  EELIRVSGYAQLAEAFYYAKYLPSHKKAVRDVEEANQRVKKLVRPFLSLNPP---TNTYL 272

Query: 802  SFLLSQGFTEDILLANLFELFMFSVDSLAGTIAWALAFMIHHEDVQQRVLKQVMNKLG-G 978
             FL SQ + E++++  +FE ++  VDS + T AWALAF+I    VQ ++ +++ N     
Sbjct: 273  HFLNSQKYDEEVIIFAIFEAYLLGVDSTSLTTAWALAFLIREPVVQDKLYQELKNLTAKN 332

Query: 979  TRKMVSVEDLTSTEMEYVHAVVKETXXXXXXXXXXXXXXXXXDTELKGMTVKAGTLVLVN 1158
              ++V VEDL   +++Y+ AV+KET                 DT LKG  +  GT V+VN
Sbjct: 333  DCEIVKVEDL--NKLQYLQAVLKETMRMKPIAPLAIPHKACRDTSLKGNKIDQGTQVMVN 390

Query: 1159 LYAVLHDERVWKEPEKFIPERFLMSASSGDAEEVKRMERSFVPFAAGRRSCPAMELAK 1332
            +YA+ H+E+VWKEP KF+PERFL +    D    K ME+S +PF+AG R C  MEL K
Sbjct: 391  IYALHHNEKVWKEPFKFMPERFLQTQ---DVVNGKGMEQSLLPFSAGMRICAGMELGK 445


>gb|AAU20771.1| (S)-canadine synthase [Thalictrum flavum subsp. glaucum]
          Length = 492

 Score =  339 bits (869), Expect = 2e-90
 Identities = 177/421 (42%), Positives = 264/421 (62%)
 Frame = +1

Query: 70   SKQRWPPGPMRFPLIGNLHQLRRGGQLVHLTLSKMAEKHGRIMTVWFGGPEPTIVVSDHE 249
            S+ +WP GP + P+IGNLHQL  GG ++H+ L+K+A+ HG +MTVW G   P IV+SD +
Sbjct: 33   SQMKWPTGPNKLPIIGNLHQL--GGDVLHVALAKLAQVHGSVMTVWIGNWRPIIVISDID 90

Query: 250  VAWEVLVTKVNDYSARQLPVMSKITSADWHTLATSSLGPTWERFRKGLQSTTLHPRIISS 429
             AWEVLV K +DY AR +P ++KI SA WHT++TS  G  W+  RKGLQS  + P  I++
Sbjct: 91   KAWEVLVNKSSDYGARDMPEITKIASASWHTISTSDAGAFWQTVRKGLQSGAMGPLNIAA 150

Query: 430  HSQLQEKDVADLISSFEQEASLNNGIVKPVPKLRKLAIRVAGRLCFGPESTMDDQFAEGI 609
             SQ QE+D+  LI +   EA+ NN IVKP+  ++K  +R+  RL FG ++  DD+F E +
Sbjct: 151  QSQFQERDMKRLIQALRDEAAQNNNIVKPLDHIKKNTVRLLTRLIFG-QTFDDDKFVESM 209

Query: 610  DWAIVEAIRLGDQARLVDMFEFTRYIPGLKPPYKELESLNQRVKEHISSYLSTHKPSSSS 789
             + I + IR+   ARL + F + +Y+P  K   +E   +  RV++ +S  LS++ P   +
Sbjct: 210  HFEIDDIIRISGYARLAEAFYYAKYLPSHKKAEREAYLVKCRVEDLVSPLLSSNPP---T 266

Query: 790  NCYLSFLLSQGFTEDILLANLFELFMFSVDSLAGTIAWALAFMIHHEDVQQRVLKQVMNK 969
            N YL FLLSQ F+E++++  +FEL++  VDS + T  WALA++I  + +Q+++ +     
Sbjct: 267  NSYLYFLLSQRFSEEVIIFCIFELYLLGVDSTSSTTTWALAYLIREQAIQEKLYQDTRMT 326

Query: 970  LGGTRKMVSVEDLTSTEMEYVHAVVKETXXXXXXXXXXXXXXXXXDTELKGMTVKAGTLV 1149
            LG    +V +ED+  ++++Y+ AVVKET                 DT L G  V  GT +
Sbjct: 327  LGDV-DLVKIEDV--SKLKYLQAVVKETMRMKPIAPLAIPHKTAKDTTLMGSKVAKGTRI 383

Query: 1150 LVNLYAVLHDERVWKEPEKFIPERFLMSASSGDAEEVKRMERSFVPFAAGRRSCPAMELA 1329
            +VNLYA+ H++ +W  P KF+PERFL     G A   K ME+SF+PF+AG R C  M+L 
Sbjct: 384  MVNLYALHHNQNIWTNPYKFMPERFL-QGEDGSASN-KAMEQSFLPFSAGMRICAGMDLG 441

Query: 1330 K 1332
            K
Sbjct: 442  K 442


>sp|B5UAQ8.1|C7195_ESCCA RecName: Full=Cheilanthifoline synthase; Short=CHS; AltName:
            Full=Cytochrome P450 719A5 gi|209571368|dbj|BAG75113.1|
            cheilanthifoline synthase [Eschscholzia californica]
          Length = 490

 Score =  336 bits (861), Expect = 2e-89
 Identities = 180/444 (40%), Positives = 271/444 (61%)
 Frame = +1

Query: 1    IMATVFLLGLLMKLLDQTFLIFGSKQRWPPGPMRFPLIGNLHQLRRGGQLVHLTLSKMAE 180
            + ATV ++  + KLL ++  I  S   WP GP + P+IGNLHQL  GG+  H+ L+ +A+
Sbjct: 8    VTATVVVVFAIAKLLKKSSSI--STMEWPKGPKKLPIIGNLHQL--GGEAFHVVLANLAK 63

Query: 181  KHGRIMTVWFGGPEPTIVVSDHEVAWEVLVTKVNDYSARQLPVMSKITSADWHTLATSSL 360
             HG +MT+W G   P IV+SD + AWEVLV K +DY+ R  P ++KI SA+W  ++ S  
Sbjct: 64   IHGTVMTIWVGAWRPMIVISDIDKAWEVLVNKSSDYAGRDFPEITKIISANWKNISCSDS 123

Query: 361  GPTWERFRKGLQSTTLHPRIISSHSQLQEKDVADLISSFEQEASLNNGIVKPVPKLRKLA 540
            GP W+  RKGLQ   L P  + S  QLQE+D+ +LI+S +++AS NNGI+KP+  L++  
Sbjct: 124  GPFWQNLRKGLQGGALAPLNVISQYQLQERDMKNLITSMQEKASKNNGILKPLDYLKEET 183

Query: 541  IRVAGRLCFGPESTMDDQFAEGIDWAIVEAIRLGDQARLVDMFEFTRYIPGLKPPYKELE 720
            IR+  RL FG +S  D+ F +G+  A+ + +R+   A L D F+F   +P  K   +E+ 
Sbjct: 184  IRLLSRLIFG-QSFNDENFVKGVHLALDDLVRISGYASLADAFKFCENLPSHKKSIREVH 242

Query: 721  SLNQRVKEHISSYLSTHKPSSSSNCYLSFLLSQGFTEDILLANLFELFMFSVDSLAGTIA 900
             +N+RV   +  YL  + P   +N YL FL SQ F+++++++ + E++   VDS A T  
Sbjct: 243  EVNERVVNLVKPYLVKNPP---TNTYLYFLNSQKFSDEVIISAVLEVYDLGVDSTASTAV 299

Query: 901  WALAFMIHHEDVQQRVLKQVMNKLGGTRKMVSVEDLTSTEMEYVHAVVKETXXXXXXXXX 1080
            WAL F++    VQ+++ K++++  GG R  V VED+  +++ Y+ AV+KET         
Sbjct: 300  WALTFLVREPRVQEKLYKEIIDLTGGERS-VKVEDV--SKLPYLQAVMKETMRMKPIAPM 356

Query: 1081 XXXXXXXXDTELKGMTVKAGTLVLVNLYAVLHDERVWKEPEKFIPERFLMSASSGDAEEV 1260
                    DT L G  V  GT ++VNLYA+ H+ +V+ EP KFIPERFL    S    ++
Sbjct: 357  AIPHKTSRDTSLMGKKVNKGTSIMVNLYAIHHNPKVFPEPYKFIPERFLQGQES-KYGDI 415

Query: 1261 KRMERSFVPFAAGRRSCPAMELAK 1332
            K ME+S +PF+AG R C  MEL K
Sbjct: 416  KEMEQSLLPFSAGMRICAGMELGK 439


>sp|B1NF19.1|C719D_ARGME RecName: Full=(S)-stylopine synthase; Short=STS; AltName:
            Full=Cytochrome P450 719A13 gi|148841092|gb|ABR14721.1|
            stylopine synthase [Argemone mexicana]
          Length = 504

 Score =  336 bits (861), Expect = 2e-89
 Identities = 179/442 (40%), Positives = 267/442 (60%), Gaps = 7/442 (1%)
 Frame = +1

Query: 28   LLMKLLDQTFLIF------GSKQRWPPGPMRFPLIGNLHQLRRGGQLVHLTLSKMAEKHG 189
            +L+ LL   F+I        SK  WP GP   P+IGN++ L  GG  +H+ L  +A+ +G
Sbjct: 24   ILLSLLFTIFIILRRNKSSSSKMVWPTGPKTLPIIGNMNIL--GGTALHVVLHNLAKTYG 81

Query: 190  RIMTVWFGGPEPTIVVSDHEVAWEVLVTKVNDYSARQLPVMSKITSADWHTLATSSLGPT 369
             +MT+W G   P IVVSD + AWEVLV K +DYSAR +P ++K+ +ADW T+++S  GP 
Sbjct: 82   NVMTIWIGSWRPVIVVSDIDRAWEVLVNKSSDYSARDMPEITKLATADWKTISSSDSGPF 141

Query: 370  WERFRKGLQSTTLHPRIISSHSQLQEKDVADLISSFEQEASLNNGIVKPVPKLRKLAIRV 549
            W   RKGLQ+  L P+ +SS S+ QE+D+   I + ++EA +NNGIVKP+  L+K  +R+
Sbjct: 142  WTNLRKGLQNVALSPQNLSSQSKFQERDIIKTIQNLKEEAKMNNGIVKPLDHLKKAMVRL 201

Query: 550  AGRLCFGPESTMDDQFAEGIDWAIVEAIRLGDQARLVDMFEFTRYIPGLKPPYKELESLN 729
              RL +G +   +D++ E +   I E IR+   ARL + F + +Y+P  K   +E+   N
Sbjct: 202  ISRLIYGQDFD-NDEYVEEMHHTIEELIRVSGYARLAEAFYYAKYLPSHKKAVREVLQAN 260

Query: 730  QRVKEHISSYLSTHKPSSSSNCYLSFLLSQGFTEDILLANLFELFMFSVDSLAGTIAWAL 909
            QRV+  +   LS + P   +N YL FL SQ + +++++  +FE ++  VDS + T AWAL
Sbjct: 261  QRVQNLVRPLLSLNSP---TNTYLHFLRSQNYEDEVIIFAIFEAYLLGVDSTSSTTAWAL 317

Query: 910  AFMIHHEDVQQRVLKQVMNKLG-GTRKMVSVEDLTSTEMEYVHAVVKETXXXXXXXXXXX 1086
            A++I   +VQ+++ +++ N      RKMV  EDL   +++Y+ AVVKET           
Sbjct: 318  AYLIREPNVQEKLYEELKNFTNDNDRKMVKFEDL--NKLQYLQAVVKETMRMKPIAPLAI 375

Query: 1087 XXXXXXDTELKGMTVKAGTLVLVNLYAVLHDERVWKEPEKFIPERFLMSASSGDAEEVKR 1266
                  +T L G  V  GT V+VN+YA+ H++ VWKEP KF PERFL    + D  + K 
Sbjct: 376  PHKACRETSLMGRKVNQGTRVMVNIYALHHNQNVWKEPYKFNPERFLQ--KNQDGVDGKA 433

Query: 1267 MERSFVPFAAGRRSCPAMELAK 1332
            ME+S +PF+AG R C  MEL K
Sbjct: 434  MEQSLLPFSAGMRICAGMELGK 455


>sp|Q50LH4.1|C7193_ESCCA RecName: Full=(S)-stylopine synthase 2; Short=STS; AltName:
            Full=Cytochrome P450 719A3; Short=EcCYP719A3;
            Short=EcCYPA gi|63108254|dbj|BAD98249.1| stylopine
            synthase [Eschscholzia californica]
          Length = 495

 Score =  330 bits (845), Expect = 1e-87
 Identities = 182/435 (41%), Positives = 261/435 (60%), Gaps = 4/435 (0%)
 Frame = +1

Query: 40   LLDQTFLIFGSKQ---RWPPGPMRFPLIGNLHQLRRGGQLVHLTLSKMAEKHGRIMTVWF 210
            LL   FL F  K     WP GP   P+IGN+H L  GG  + + L  +A+ HGR+MT+W 
Sbjct: 22   LLISIFLFFRRKSPNMAWPEGPKTLPIIGNMHLL--GGTALQVVLYNLAKVHGRVMTIWI 79

Query: 211  GGPEPTIVVSDHEVAWEVLVTKVNDYSARQLPVMSKITSADWHTLATSSLGPTWERFRKG 390
            G   P IVVSD E AWEVLV K +DYSAR +P ++KI +ADW T++TS  GP W   RKG
Sbjct: 80   GSWRPVIVVSDIEQAWEVLVNKSSDYSARDMPDITKIVTADWRTISTSDSGPHWSNLRKG 139

Query: 391  LQSTTLHPRIISSHSQLQEKDVADLISSFEQEASLNNGIVKPVPKLRKLAIRVAGRLCFG 570
            LQ+  + P  +++  Q QEKD+  +I   EQEA  NNGIVKP+  L+K  IR+  RL FG
Sbjct: 140  LQNIAISPNNLAAQFQFQEKDIIKMIQILEQEAKDNNGIVKPLDHLKKATIRLISRLVFG 199

Query: 571  PESTMDDQFAEGIDWAIVEAIRLGDQARLVDMFEFTRYIPGLKPPYKELESLNQRVKEHI 750
             +   +D++ E +  AI E IR+   ARL + F + +Y+P  +   + +E L Q VK  I
Sbjct: 200  RDFE-EDKYVEDMHHAIEELIRISGYARLAEAFYYAKYLPSHRKAVRYVEELKQIVKNLI 258

Query: 751  SSYLSTHKPSSSSNCYLSFLLSQGFTEDILLANLFELFMFSVDSLAGTIAWALAFMIHHE 930
              +LS + P   +N YL FL SQ + E++++  +FE ++  VDS + T AWALA+++   
Sbjct: 259  RPFLSVNPP---TNTYLHFLRSQNYDEEVVIFAIFETYLLGVDSTSSTTAWALAYLVREP 315

Query: 931  DVQQRVLKQVMN-KLGGTRKMVSVEDLTSTEMEYVHAVVKETXXXXXXXXXXXXXXXXXD 1107
             VQ R+ +++ +      RK++ VED+   +++Y+ AV+KET                 D
Sbjct: 316  SVQDRLHQELDHFAKQNDRKILKVEDM--NKLQYLQAVIKETMRMKPIAPLAIPHKACKD 373

Query: 1108 TELKGMTVKAGTLVLVNLYAVLHDERVWKEPEKFIPERFLMSASSGDAEEVKRMERSFVP 1287
            T L G  +  GT V+VNLYA+ H++ V+ +P KF+PERFL    + DA+  K ME+S +P
Sbjct: 374  TSLMGNKINKGTRVMVNLYALHHNKNVFNDPFKFMPERFL-KVDNQDAKG-KAMEQSLLP 431

Query: 1288 FAAGRRSCPAMELAK 1332
            F+AG R C  MEL K
Sbjct: 432  FSAGMRICAGMELGK 446


>gb|AGL76711.1| (S)-canadine synthase, partial [Coptis chinensis]
          Length = 491

 Score =  329 bits (844), Expect = 1e-87
 Identities = 176/443 (39%), Positives = 272/443 (61%)
 Frame = +1

Query: 4    MATVFLLGLLMKLLDQTFLIFGSKQRWPPGPMRFPLIGNLHQLRRGGQLVHLTLSKMAEK 183
            +A VF    ++++L  +  +   + +WP GP + P+IGNLHQL  G  ++H+ L+K+A+ 
Sbjct: 12   VAIVFATTTIIRILFSSSSL--PQMKWPSGPRKLPIIGNLHQL--GDDVLHVALAKLAKV 67

Query: 184  HGRIMTVWFGGPEPTIVVSDHEVAWEVLVTKVNDYSARQLPVMSKITSADWHTLATSSLG 363
            HG +MT+W G   P IV+SD E AWEVLV K  DY AR +P ++KI SA WHT++TS  G
Sbjct: 68   HGSMMTIWIGSWRPVIVISDLEKAWEVLVNKSADYGARDMPEITKIASASWHTISTSDAG 127

Query: 364  PTWERFRKGLQSTTLHPRIISSHSQLQEKDVADLISSFEQEASLNNGIVKPVPKLRKLAI 543
            P W+  RKGLQS  + P  +++ +Q QE+ +  LI +   EA+ NNGIVKP+  ++K  +
Sbjct: 128  PFWQNVRKGLQSGAMGPFNVAAQNQHQERGMKRLIKAMSDEAANNNGIVKPLDHIKKNTV 187

Query: 544  RVAGRLCFGPESTMDDQFAEGIDWAIVEAIRLGDQARLVDMFEFTRYIPGLKPPYKELES 723
            R+  RL FG ++  D++F E + + I + IR+   ARL + F + +Y+P  K   +E   
Sbjct: 188  RLLTRLIFG-QNFDDNKFIESMHYEIEDIIRISGYARLAEAFYYAKYLPSHKKAEREAFL 246

Query: 724  LNQRVKEHISSYLSTHKPSSSSNCYLSFLLSQGFTEDILLANLFELFMFSVDSLAGTIAW 903
            +  RV+E +   LS++ P   +N YL FLLSQ F E++++  +FEL++  VDS + T  W
Sbjct: 247  VKCRVQELVRPLLSSNPP---TNSYLYFLLSQNFEEEVIIFCIFELYLLGVDSTSSTTTW 303

Query: 904  ALAFMIHHEDVQQRVLKQVMNKLGGTRKMVSVEDLTSTEMEYVHAVVKETXXXXXXXXXX 1083
            ALA++I  +  Q+++ + +   LG    +V +ED+   +++Y+  VVKET          
Sbjct: 304  ALAYLIREQGAQEKLYQDIRMTLGDV-DLVKIEDV--NKLKYLQGVVKETMRMKPIAPLA 360

Query: 1084 XXXXXXXDTELKGMTVKAGTLVLVNLYAVLHDERVWKEPEKFIPERFLMSASSGDAEEVK 1263
                   +T L G  V  GT ++VNLYA+ H++ +W +P KF+PERFL  A +G A   K
Sbjct: 361  IPHKTAKETTLMGTKVAKGTRIMVNLYALHHNQNIWPDPYKFMPERFLEGA-TGTAYN-K 418

Query: 1264 RMERSFVPFAAGRRSCPAMELAK 1332
             ME+SF+PF+AG R C  M+L K
Sbjct: 419  AMEQSFLPFSAGMRICAGMDLGK 441


>sp|Q948Y1.1|C719A_COPJA RecName: Full=(S)-canadine synthase; AltName:
            Full=(S)-tetrahydrocolumbamine oxidase
            (methylenedioxy-bridge-forming); AltName: Full=Cytochrome
            P450 719A1 gi|15822820|dbj|BAB68769.1| methylenedioxy
            bridge-forming enzyme [Coptis japonica]
          Length = 491

 Score =  329 bits (844), Expect = 1e-87
 Identities = 175/443 (39%), Positives = 270/443 (60%)
 Frame = +1

Query: 4    MATVFLLGLLMKLLDQTFLIFGSKQRWPPGPMRFPLIGNLHQLRRGGQLVHLTLSKMAEK 183
            +A VF    ++++L  +  +   + +WP GP + P+IGNLHQL  G  ++H+ L+K+A+ 
Sbjct: 12   VAIVFATTTIIRILFSSSSL--PQMKWPSGPRKLPIIGNLHQL--GDDVLHVALAKLAKV 67

Query: 184  HGRIMTVWFGGPEPTIVVSDHEVAWEVLVTKVNDYSARQLPVMSKITSADWHTLATSSLG 363
            HG +MT+W G   P IV+SD E AWEVLV K  DY AR +P ++KI SA WHT++TS  G
Sbjct: 68   HGSVMTIWIGSWRPVIVISDIEKAWEVLVNKSADYGARDMPEITKIASASWHTISTSDAG 127

Query: 364  PTWERFRKGLQSTTLHPRIISSHSQLQEKDVADLISSFEQEASLNNGIVKPVPKLRKLAI 543
              W+  RKGLQS  + P  +++ +Q QE+D+  LI +   EA+ NNGIVKP+  ++K  +
Sbjct: 128  SFWQNVRKGLQSGAMGPLNVAAQNQYQERDMKRLIKAMSDEAANNNGIVKPLDHIKKNTV 187

Query: 544  RVAGRLCFGPESTMDDQFAEGIDWAIVEAIRLGDQARLVDMFEFTRYIPGLKPPYKELES 723
            R+  RL FG ++  D++F E + + I + IR+   ARL + F + +Y+P  K   +E   
Sbjct: 188  RLLTRLIFG-QAFDDNKFIESMHYEIEDIIRISGYARLAEAFYYAKYLPSHKKAEREAFL 246

Query: 724  LNQRVKEHISSYLSTHKPSSSSNCYLSFLLSQGFTEDILLANLFELFMFSVDSLAGTIAW 903
            +  RV+E +   LS+  P   +N YL FLLSQ F E++++  +FEL++  VDS + T  W
Sbjct: 247  VKCRVEELVRPLLSSKPP---TNSYLYFLLSQNFEEEVIIFCIFELYLLGVDSTSSTTTW 303

Query: 904  ALAFMIHHEDVQQRVLKQVMNKLGGTRKMVSVEDLTSTEMEYVHAVVKETXXXXXXXXXX 1083
            ALA++I  +  Q+++ + +   LG    +V +ED+   +++Y+  VVKET          
Sbjct: 304  ALAYLIREQGAQEKLYQDIRMTLGDV-DLVKIEDV--NKLKYLQGVVKETMRMKPIAPLA 360

Query: 1084 XXXXXXXDTELKGMTVKAGTLVLVNLYAVLHDERVWKEPEKFIPERFLMSASSGDAEEVK 1263
                   +T L G  V  GT ++VNLYA+ H++ +W +P KF+PERFL    +G A   K
Sbjct: 361  IPHKTAKETTLMGTKVAKGTRIMVNLYALHHNQNIWPDPYKFMPERFL-EGETGTAYN-K 418

Query: 1264 RMERSFVPFAAGRRSCPAMELAK 1332
             ME+SF+PF+AG R C  M+L K
Sbjct: 419  AMEQSFLPFSAGMRICAGMDLGK 441


>gb|ACO90219.1| stylopine synthase [Eschscholzia californica]
          Length = 495

 Score =  329 bits (844), Expect = 1e-87
 Identities = 181/437 (41%), Positives = 266/437 (60%), Gaps = 6/437 (1%)
 Frame = +1

Query: 40   LLDQTFLIF---GSKQRWPPGPMRFPLIGNLHQLRRGGQLVHLTLSKMAEKHGRIMTVWF 210
            LL   FL F    SK  WP GP   P+IGN+H L  GG  + + L  +A+ HG +MT+W 
Sbjct: 22   LLISIFLFFTRKSSKMVWPAGPKTLPIIGNMHLL--GGTALQVVLHNLAKVHGSVMTIWI 79

Query: 211  GGPEPTIVVSDHEVAWEVLVTKVNDYSARQLPVMSKITSADWHTLATSSLGPTWERFRKG 390
            G   P IVVSD E AWEVLV K +DYSAR +P ++KI SADW T++TS  GP W   RKG
Sbjct: 80   GSWRPVIVVSDIERAWEVLVNKSSDYSARDMPDITKIISADWKTISTSDSGPHWTNLRKG 139

Query: 391  LQSTTLHPRIISSHSQLQEKDVADLISSFEQEASLNNGIVKPVPKLRKLAIRVAGRLCFG 570
            LQ+  L P  +++  Q QEKD+  +I + ++EA  NNGIVKP+  ++K  +R+  RL FG
Sbjct: 140  LQNVALSPHNLAAQFQFQEKDMTKMIQTLQEEARNNNGIVKPLDHMKKATLRLISRLVFG 199

Query: 571  PESTMDDQFAEGIDWAIVEAIRLGDQARLVDMFEFTRYIPGLKPPYKELESLNQRVKEHI 750
             +   +D++ + +  AI E IR+   ARL + F + +Y+P  K   +E+E   +RV+  +
Sbjct: 200  QDFN-NDKYVDDMHLAIEELIRVSGYARLAEAFYYAKYLPSHKKAVREVEEAQRRVQNLV 258

Query: 751  SSYLSTHKPSSSSNCYLSFLLSQGFTEDILLANLFELFMFSVDSLAGTIAWALAFMIHHE 930
            S +LS + P   +N YL FL SQ + +++++  +FE ++  VDS + T AWALAF+I   
Sbjct: 259  SPFLSLNPP---TNTYLHFLRSQKYDDEVIIFAIFEAYLLGVDSTSLTTAWALAFLIRES 315

Query: 931  DVQQRV---LKQVMNKLGGTRKMVSVEDLTSTEMEYVHAVVKETXXXXXXXXXXXXXXXX 1101
            +VQ+++   L+   +K+   RK++ VED+   +++Y+ AV+KET                
Sbjct: 316  NVQEKLYQELESFASKM--DRKILKVEDI--NKLQYLQAVIKETMRMKPIAPLAIPHKAC 371

Query: 1102 XDTELKGMTVKAGTLVLVNLYAVLHDERVWKEPEKFIPERFLMSASSGDAEEVKRMERSF 1281
             DT L G  +  GT V+VN+YA+ H++ V+ +P KF+PERF M   S DA   K ME+S 
Sbjct: 372  RDTSLMGKKIDKGTRVMVNIYALHHNKNVFNDPFKFMPERF-MKVDSQDANG-KAMEQSL 429

Query: 1282 VPFAAGRRSCPAMELAK 1332
            +PF+AG R C  MEL K
Sbjct: 430  LPFSAGMRICAGMELGK 446


>sp|Q50LH3.1|C7192_ESCCA RecName: Full=(S)-stylopine synthase 1; Short=STS; AltName:
            Full=Cytochrome P450 719A2; Short=EcCYP719A2;
            Short=EcCYPB gi|63108256|dbj|BAD98250.1| stylopine
            synthase [Eschscholzia californica]
          Length = 495

 Score =  328 bits (841), Expect = 3e-87
 Identities = 178/435 (40%), Positives = 265/435 (60%), Gaps = 4/435 (0%)
 Frame = +1

Query: 40   LLDQTFLIF---GSKQRWPPGPMRFPLIGNLHQLRRGGQLVHLTLSKMAEKHGRIMTVWF 210
            LL   FL F    SK  WP GP   P+IGN+H L  GG  + + L  +A+ HG +MT+W 
Sbjct: 22   LLISIFLFFTRKSSKMVWPAGPKTLPIIGNMHLL--GGTALQVVLHNLAKVHGSVMTIWI 79

Query: 211  GGPEPTIVVSDHEVAWEVLVTKVNDYSARQLPVMSKITSADWHTLATSSLGPTWERFRKG 390
            G   P IVVSD E AWEVLV K +DYSAR +P ++KI SADW T++TS  GP W   RKG
Sbjct: 80   GSWRPVIVVSDIERAWEVLVNKSSDYSARDMPDITKIISADWKTISTSDSGPHWTNLRKG 139

Query: 391  LQSTTLHPRIISSHSQLQEKDVADLISSFEQEASLNNGIVKPVPKLRKLAIRVAGRLCFG 570
            LQ+  L P  +++  Q QEKD+  +I + E+EA  NNGIVKP+  ++K  +R+  RL FG
Sbjct: 140  LQNVALSPHNLAAQFQFQEKDMTKMIQTLEEEARNNNGIVKPLDHMKKATLRLISRLVFG 199

Query: 571  PESTMDDQFAEGIDWAIVEAIRLGDQARLVDMFEFTRYIPGLKPPYKELESLNQRVKEHI 750
             +   +D++ + +  AI E IR+   ARL + F + +Y+P  K   +E+E   +RV+  +
Sbjct: 200  QDFN-NDKYVDDMHLAIEELIRVSGYARLAEAFYYAKYLPSHKKAVREVEEAQRRVQNLV 258

Query: 751  SSYLSTHKPSSSSNCYLSFLLSQGFTEDILLANLFELFMFSVDSLAGTIAWALAFMIHHE 930
            S +LS + P   +N YL FL SQ + +++++  +FE ++  VDS + T AWALAF+I   
Sbjct: 259  SPFLSLNPP---TNTYLHFLRSQKYDDEVIIFAIFEAYLLGVDSTSLTTAWALAFLIREP 315

Query: 931  DVQQRVLKQVMNKLG-GTRKMVSVEDLTSTEMEYVHAVVKETXXXXXXXXXXXXXXXXXD 1107
            +VQ+++ +++ +      R+++ VED+   +++Y+ AV+KET                 D
Sbjct: 316  NVQEKLYQELESFASKNDRRILKVEDI--NKLQYLQAVIKETMRMKPIAPLAIPHKACRD 373

Query: 1108 TELKGMTVKAGTLVLVNLYAVLHDERVWKEPEKFIPERFLMSASSGDAEEVKRMERSFVP 1287
            T L G  +  GT V+VN++A+ H++ V+ +P KF+PERF M   S DA   K ME+S +P
Sbjct: 374  TSLMGKKIDKGTRVMVNIFALHHNKNVFNDPFKFMPERF-MKVDSQDANG-KAMEQSLLP 431

Query: 1288 FAAGRRSCPAMELAK 1332
            F+AG R C  MEL K
Sbjct: 432  FSAGMRICAGMELGK 446


>sp|B1NF20.1|C719E_ARGME RecName: Full=Cheilanthifoline synthase; Short=CHS; AltName:
            Full=Cytochrome P450 719A14 gi|148841094|gb|ABR14722.1|
            cheilanthifoline synthase [Argemone mexicana]
          Length = 494

 Score =  322 bits (826), Expect = 2e-85
 Identities = 169/445 (37%), Positives = 266/445 (59%), Gaps = 1/445 (0%)
 Frame = +1

Query: 1    IMATVFLLGLLMKLLDQTFLIFGSKQRWPPGPMRFPLIGNLHQLRRGGQLVHLTLSKMAE 180
            I   + +LG+   LL ++     S   WP GP + P+IGNLHQL  GG + H+ L+ +A+
Sbjct: 9    ISTVIIVLGIAKFLLGKSSSSSLSTMEWPVGPKKLPIIGNLHQL--GGDVFHVVLANLAK 66

Query: 181  KHGRIMTVWFGGPEPTIVVSDHEVAWEVLVTKVNDYSARQLPVMSKITSADWHTLATSSL 360
             +G + T+W G   P I+VSD + AWEVLV K +DYSAR +P ++KI SA+W  ++ S  
Sbjct: 67   VYGSVFTIWVGSWRPMIIVSDIDKAWEVLVNKSSDYSARDMPDITKIISANWKNISCSDS 126

Query: 361  GPTWERFRKGLQSTTLHPRIISSHSQLQEKDVADLISSFEQEASLNNGIVKPVPKLRKLA 540
            GP W   RKGLQ   L P  ++S   LQE+D+ +LI+S  ++AS  NGI+KP+  L++  
Sbjct: 127  GPFWHNLRKGLQGVALTPLNVASQYHLQERDMKNLINSMYKDASRKNGILKPLDYLKEET 186

Query: 541  IRVAGRLCFGPESTMDDQFAEGIDWAIVEAIRLGDQARLVDMFEFTRYIPGLKPPYKELE 720
            +R+  RL FG +   D++   G+  A+ + +R+   A L D F+F   +P  K   +E+ 
Sbjct: 187  VRLLSRLIFG-QDFQDEKLVVGMHHALDDLVRISGYASLADAFKFCENLPSHKKSIREVH 245

Query: 721  SLNQRVKEHISSYLSTHKPSSSSNCYLSFLLSQGFTEDILLANLFELFMFSVDSLAGTIA 900
             + +RV+  I  ++ ++ P   +N YL FL +Q F EDI+++ + E++   VDS A T  
Sbjct: 246  EVKKRVENLIRPHIVSNPP---TNTYLYFLKTQDFNEDIIISAILEVYDLGVDSTASTTV 302

Query: 901  WALAFMIHHEDVQQRVLKQVMNKLGGTRKMVSVEDLTSTEMEYVHAVVKETXXXXXXXXX 1080
            WAL F++  +++Q+++ ++++N  GG R  V VED+   +M Y+ AV+KET         
Sbjct: 303  WALTFLVREQEIQEKLYREIVNVTGGKRS-VKVEDV--NKMPYLQAVMKETMRMKPIAPM 359

Query: 1081 XXXXXXXXDTELKGMTVKAGTLVLVNLYAVLHDERVWKEPEKFIPERFLMSASSGDA-EE 1257
                    DT L G  +  G++++VNLYA+ H+ +V+ EP KF+PERFL   +S ++   
Sbjct: 360  AIPHKTSKDTSLMGKKINKGSVIMVNLYAIHHNPKVFPEPYKFMPERFLKDVNSDESLGN 419

Query: 1258 VKRMERSFVPFAAGRRSCPAMELAK 1332
            +K ME S + F+AG R C  MEL K
Sbjct: 420  IKTMESSLLAFSAGMRICAGMELGK 444


>gb|AFI57927.1| cytochrome P450, partial [Papaver somniferum]
          Length = 488

 Score =  320 bits (820), Expect = 9e-85
 Identities = 177/453 (39%), Positives = 269/453 (59%), Gaps = 9/453 (1%)
 Frame = +1

Query: 1    IMATVFLLGLLMKLLD---QTFLIF-----GSKQRWPPGPMRFPLIGNLHQLRRGGQLVH 156
            IM+ +++L L+  +L       +IF      S   WP GP   P+IGNLH L  GG  +H
Sbjct: 2    IMSNLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHIL--GGTALH 59

Query: 157  LTLSKMAEKHGRIMTVWFGGPEPTIVVSDHEVAWEVLVTKVNDYSARQLPVMSKITSADW 336
            + L K+AE +G +MT+W G  +P I+VSD + AWEVLV K +DYSAR++P ++KI +A+W
Sbjct: 60   VVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTANW 119

Query: 337  HTLATSSLGPTWERFRKGLQSTTLHPRIISSHSQLQEKDVADLISSFEQEASLNNGIVKP 516
             T+++S  GP W   RKGLQS  L P+ ++S +  QE+D+  LI + + EA+LN+G+VKP
Sbjct: 120  RTISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAALNSGMVKP 179

Query: 517  VPKLRKLAIRVAGRLCFGPESTMDDQFAEGIDWAIVEAIRLGDQARLVDMFEFTRYIPGL 696
            +  L+K  +R+  RL +G +   DD++ E +   I   IR+   A+L ++F + +Y+P  
Sbjct: 180  LDHLKKATVRLISRLIYGQDFD-DDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPSH 238

Query: 697  KPPYKELESLNQRVKEHISSYLSTHKPSSSSNCYLSFLLSQGFTEDILLANLFELFMFSV 876
            K      E   +RV   +  +L +   + ++N YL FL SQ + E++++  +FE ++  V
Sbjct: 239  KRAVTGAEEAKRRVIALVRPFLQS---NPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGV 295

Query: 877  DSLAGTIAWALAFMIHHEDVQQRVLKQVMN-KLGGTRKMVSVEDLTSTEMEYVHAVVKET 1053
            DS + T AWALAF+I    VQ+++ +++ N      R M+ VED+   ++ Y+ AVVKET
Sbjct: 296  DSTSSTTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDV--NKLPYLQAVVKET 353

Query: 1054 XXXXXXXXXXXXXXXXXDTELKGMTVKAGTLVLVNLYAVLHDERVWKEPEKFIPERFLMS 1233
                             DT L G  V  GT V+VN++A+ H E+VWKEP KF+PERFL  
Sbjct: 354  MRMKPIAPLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFMPERFLQ- 412

Query: 1234 ASSGDAEEVKRMERSFVPFAAGRRSCPAMELAK 1332
                  +  K ME+S +PF+AG R C  MEL K
Sbjct: 413  ------KHDKAMEQSLLPFSAGMRICAGMELGK 439


>dbj|BAF98470.1| cytochrome P450 [Coptis japonica var. dissecta]
          Length = 491

 Score =  318 bits (815), Expect = 3e-84
 Identities = 174/445 (39%), Positives = 265/445 (59%), Gaps = 1/445 (0%)
 Frame = +1

Query: 1    IMATVFLLGLLMKLLDQTFLIFGSKQRWPPGPMRFPLIGNLHQLRRGGQLVHLTLSKMAE 180
            I +TV ++ ++  ++  +     SK++WP GP R P+IGNLH L  GG L+H+TL+K+A+
Sbjct: 9    IGSTVAIVLVITTIVRMSSSSSSSKKKWPSGPKRLPIIGNLHLL--GGDLLHVTLAKLAK 66

Query: 181  KHGRIMTVWFGGPEPTIVVSDHEVAWEVLVTKVNDYSARQLPVMSKITSADWHTLATSSL 360
             HG +MT+W G   P IV+SD   AWEVLV+K  +Y  R  P + K  +   + ++ S +
Sbjct: 67   VHGSVMTIWIGRWRPIIVISDINSAWEVLVSKSAEYGQRDTPDIFKTLTVGQNNISMSDI 126

Query: 361  GPTWERFRKGLQSTTLHPRIISSHSQLQEKDVADLISSFEQEASLNNGIVKPVPKLRKLA 540
            GP W   RKGLQ+  L P  +++ +Q +E+DV  LI    +EA   NGI+KP+  ++K  
Sbjct: 127  GPFWHNVRKGLQNGALSPLNVAAQTQFREEDVKRLIHEMSREALNKNGIIKPLDHMKKNT 186

Query: 541  IRVAGRLCFGPESTMD-DQFAEGIDWAIVEAIRLGDQARLVDMFEFTRYIPGLKPPYKEL 717
             R+ GRL FGP  T D D+F E + + I + +RL   ARL + F + +Y+P  K   +E 
Sbjct: 187  ARLLGRLIFGP--TFDNDKFVESVLYEIEDVLRLSGYARLTEAFYYAKYLPSQKKVAREA 244

Query: 718  ESLNQRVKEHISSYLSTHKPSSSSNCYLSFLLSQGFTEDILLANLFELFMFSVDSLAGTI 897
                 R++E +   LS++ P   +N YL FL SQ ++++I++   FELF+  VDS + T 
Sbjct: 245  YLAKYRIEELMRPLLSSNPP---TNSYLYFLQSQNYSKEIIIFCTFELFLLGVDSTSSTA 301

Query: 898  AWALAFMIHHEDVQQRVLKQVMNKLGGTRKMVSVEDLTSTEMEYVHAVVKETXXXXXXXX 1077
             WALA++IH + VQ+++ + +   +G    +V +EDL  ++++Y+ AVVKET        
Sbjct: 302  TWALAYLIHEQAVQEKLNEDIRMTIGDV-DLVKIEDL--SKLKYLQAVVKETMRMKPIAP 358

Query: 1078 XXXXXXXXXDTELKGMTVKAGTLVLVNLYAVLHDERVWKEPEKFIPERFLMSASSGDAEE 1257
                     DT L G  V  GT ++VNLYA+ H+E +W EP KF+PERFL   +   +  
Sbjct: 359  LAIPHKTANDTTLMGTKVARGTQIMVNLYALHHNEDIWPEPYKFMPERFLQGENV--SAN 416

Query: 1258 VKRMERSFVPFAAGRRSCPAMELAK 1332
             K ME+SF+PF AG R C  M+L K
Sbjct: 417  NKAMEQSFLPFGAGMRICAGMDLGK 441


>gb|ADB89213.1| cheilanthifoline synthase [Papaver somniferum]
          Length = 492

 Score =  315 bits (808), Expect = 2e-83
 Identities = 168/431 (38%), Positives = 256/431 (59%), Gaps = 6/431 (1%)
 Frame = +1

Query: 58   LIFGSKQ-----RWPPGPMRFPLIGNLHQLRRGGQLVHLTLSKMAEKHGRIMTVWFGGPE 222
            L+FG K       WP GP   P+IGNLHQL  GG+  H+ L+ +A+ +G + T+W G   
Sbjct: 21   LLFGKKSSMSTMEWPSGPKTLPIIGNLHQL--GGEAFHVCLANLAKVYGGVFTIWVGSWR 78

Query: 223  PTIVVSDHEVAWEVLVTKVNDYSARQLPVMSKITSADWHTLATSSLGPTWERFRKGLQST 402
            P IV+SD + AWEVLV K +DYSAR +P ++KI SA+W  ++    GP W   RKGLQ  
Sbjct: 79   PFIVISDVDKAWEVLVNKSSDYSARDMPDITKIISANWKNISHGDSGPFWHNLRKGLQGV 138

Query: 403  TLHPRIISSHSQLQEKDVADLISSFEQEASLNNGIVKPVPKLRKLAIRVAGRLCFGPEST 582
             L P  ++S   LQE+D+ +LI S +++AS  NGI+KP+  +++  +R+  RL FG +  
Sbjct: 139  ALTPFNVASQYHLQERDMQNLIKSMKKKASQKNGILKPLDYVKEETVRLLSRLIFG-QDF 197

Query: 583  MDDQFAEGIDWAIVEAIRLGDQARLVDMFEFTRYIPGLKPPYKELESLNQRVKEHISSYL 762
            +D+ F  G+  A+ E + +   A L D F+F   +P  K   + + ++  R    I  ++
Sbjct: 198  VDEDFVVGMHQALDELVSISGYASLADAFKFCENLPSHKKTVRAVHAIKIRFDNLIRPHI 257

Query: 763  STHKPSSSSNCYLSFLLSQGFTEDILLANLFELFMFSVDSLAGTIAWALAFMIHHEDVQQ 942
             ++ P   +N YL FLLSQ F+ED++++ + E++   VDS A T  WAL F++  + +Q+
Sbjct: 258  VSNPP---TNTYLHFLLSQDFSEDVIISAILEVYDLGVDSTASTTVWALTFLVREQKIQE 314

Query: 943  RVLKQVMNKLGGTRKMVSVEDLTSTEMEYVHAVVKETXXXXXXXXXXXXXXXXXDTELKG 1122
            ++ +++ N  GG +K V VEDL   ++ Y+ AV+KET                 DT L G
Sbjct: 315  KLYREINNVTGG-KKPVKVEDL--NKLPYLQAVMKETMRMKPIAPMAIPHKASKDTSLMG 371

Query: 1123 MTVKAGTLVLVNLYAVLHDERVWKEPEKFIPERFLMSASS-GDAEEVKRMERSFVPFAAG 1299
              +  G +V+VNLYA+ H+  V+ EP KF+PERFL  A+S G   ++K+ME S + F+AG
Sbjct: 372  KKINKGAVVMVNLYAIHHNPAVFPEPYKFMPERFLKDANSDGSLGDIKKMESSLLAFSAG 431

Query: 1300 RRSCPAMELAK 1332
             R C  MEL K
Sbjct: 432  MRICAGMELGK 442


>gb|AFB74615.1| cytochrome P450 [Papaver somniferum]
          Length = 486

 Score =  315 bits (806), Expect = 4e-83
 Identities = 177/453 (39%), Positives = 268/453 (59%), Gaps = 9/453 (1%)
 Frame = +1

Query: 1    IMATVFLLGLLMKLLD---QTFLIF-----GSKQRWPPGPMRFPLIGNLHQLRRGGQLVH 156
            IM+ +++L L+  +L       +IF      S   WP GP   P+IGNLH L  GG  +H
Sbjct: 2    IMSNLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHIL--GGTALH 59

Query: 157  LTLSKMAEKHGRIMTVWFGGPEPTIVVSDHEVAWEVLVTKVNDYSARQLPVMSKITSADW 336
            + L K+AE +G +MT+W G  +P I+VSD + AWEVLV K +DYSAR++P ++KI +A+W
Sbjct: 60   VVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTANW 119

Query: 337  HTLATSSLGPTWERFRKGLQSTTLHPRIISSHSQLQEKDVADLISSFEQEASLNNGIVKP 516
             T+++S  GP W   RKGLQS  L P+ ++S +  QE+D+  LI + + EA+  +G+VKP
Sbjct: 120  RTISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAA--SGMVKP 177

Query: 517  VPKLRKLAIRVAGRLCFGPESTMDDQFAEGIDWAIVEAIRLGDQARLVDMFEFTRYIPGL 696
            +  L+K  +R+  RL +G +   DD++ E +   I   IR+   A+L ++F + +Y+PG 
Sbjct: 178  LDHLKKATVRLISRLIYGQDFD-DDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPGH 236

Query: 697  KPPYKELESLNQRVKEHISSYLSTHKPSSSSNCYLSFLLSQGFTEDILLANLFELFMFSV 876
            K      E   +RV   +  +L +   + ++N YL FL SQ + E++++  +FE ++  V
Sbjct: 237  KRAVTGAEEAKRRVIALVRPFLQS---NPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGV 293

Query: 877  DSLAGTIAWALAFMIHHEDVQQRVLKQVMN-KLGGTRKMVSVEDLTSTEMEYVHAVVKET 1053
            DS + T AWALAF+I    VQ+++ +++ N      R M+ VED+   ++ Y+ AVVKET
Sbjct: 294  DSTSSTTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDV--NKLPYLQAVVKET 351

Query: 1054 XXXXXXXXXXXXXXXXXDTELKGMTVKAGTLVLVNLYAVLHDERVWKEPEKFIPERFLMS 1233
                             DT L G  V  GT V+VN++A+ H E+VWKEP KFIPERFL  
Sbjct: 352  MRMKPIAPLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQ- 410

Query: 1234 ASSGDAEEVKRMERSFVPFAAGRRSCPAMELAK 1332
                  +  K ME+S +PF+AG R C  MEL K
Sbjct: 411  ------KHDKAMEQSLLPFSAGMRICAGMELGK 437


>dbj|BAG75116.1| cytochrome P450 [Eschscholzia californica]
          Length = 495

 Score =  314 bits (805), Expect = 5e-83
 Identities = 178/435 (40%), Positives = 251/435 (57%), Gaps = 4/435 (0%)
 Frame = +1

Query: 40   LLDQTFLIF---GSKQRWPPGPMRFPLIGNLHQLRRGGQLVHLTLSKMAEKHGRIMTVWF 210
            LL   FL F    SK  WP GP   P+IGN+H L  GG  + + L  +A+ HG +MT+W 
Sbjct: 22   LLISMFLFFTRKSSKMVWPQGPKTLPIIGNMHLL--GGTALQVVLHNLAKVHGSVMTIWI 79

Query: 211  GGPEPTIVVSDHEVAWEVLVTKVNDYSARQLPVMSKITSADWHTLATSSLGPTWERFRKG 390
            G   P IVVSD E AWEVLV K +DYSAR+LP + K  +AD  T+AT   GP W   RKG
Sbjct: 80   GSWRPVIVVSDIERAWEVLVNKSSDYSARELPDIIKYNTADCRTIATCDSGPHWSNLRKG 139

Query: 391  LQSTTLHPRIISSHSQLQEKDVADLISSFEQEASLNNGIVKPVPKLRKLAIRVAGRLCFG 570
            LQ+  L P  +++  Q QEKDV  +I   EQEA   NGIVKP+  L+K  IR+  RL FG
Sbjct: 140  LQNVALSPNNLAAQFQFQEKDVIKMIDILEQEAINKNGIVKPLDHLKKATIRLISRLVFG 199

Query: 571  PESTMDDQFAEGIDWAIVEAIRLGDQARLVDMFEFTRYIPGLKPPYKELESLNQRVKEHI 750
             +   DD++ E +  AI E IR+   A+L + F + +Y+P  K   +  E   Q V   +
Sbjct: 200  QDFN-DDKYVEDLHQAIEELIRMSGYAQLAEAFYYAKYLPSHKKAIRHAELTKQIVTNLV 258

Query: 751  SSYLSTHKPSSSSNCYLSFLLSQGFTEDILLANLFELFMFSVDSLAGTIAWALAFMIHHE 930
              +LS + P   +N YL FL SQ + E++++  +FE ++  VDS + T AWALA+++   
Sbjct: 259  RPFLSLNPP---TNSYLHFLQSQKYDEEMVIFAIFETYLLGVDSTSSTTAWALAYLVREP 315

Query: 931  DVQQRVLKQVMNKLG-GTRKMVSVEDLTSTEMEYVHAVVKETXXXXXXXXXXXXXXXXXD 1107
            +VQ R+  ++ N      RK++ VE +   +++Y+ AV KET                 D
Sbjct: 316  NVQDRLYNELNNYANYNDRKILKVEVI--NKLQYLQAVTKETMRMKPIAPLAIPHKACRD 373

Query: 1108 TELKGMTVKAGTLVLVNLYAVLHDERVWKEPEKFIPERFLMSASSGDAEEVKRMERSFVP 1287
            T L G  +  GT V+VNL+A+ H+E V+ +P KF+PERFL    + +   +K ME+S +P
Sbjct: 374  TSLMGTKIDKGTKVMVNLHALHHNENVFTDPFKFMPERFL--KVNNEDVNMKAMEQSLLP 431

Query: 1288 FAAGRRSCPAMELAK 1332
            F+AG R C  MEL K
Sbjct: 432  FSAGMRICAGMELGK 446


>dbj|BAG75115.1| cytochrome P450 [Eschscholzia californica]
          Length = 494

 Score =  307 bits (786), Expect = 8e-81
 Identities = 168/435 (38%), Positives = 251/435 (57%), Gaps = 4/435 (0%)
 Frame = +1

Query: 40   LLDQTFLIF---GSKQRWPPGPMRFPLIGNLHQLRRGGQLVHLTLSKMAEKHGRIMTVWF 210
            LL   FL F    SK  WP GP   P+IGN+H L  G + + + L  +++ HG +MT+W 
Sbjct: 22   LLISMFLFFTRKSSKMVWPKGPKTLPIIGNMHLLG-GSKALQVILHNLSKVHGSVMTIWI 80

Query: 211  GGPEPTIVVSDHEVAWEVLVTKVNDYSARQLPVMSKITSADWHTLATSSLGPTWERFRKG 390
            G   P IVVS+ E  WEVLV K +DYS R +P + K  SAD+ T++TS  GP W   RKG
Sbjct: 81   GRWRPVIVVSNIERVWEVLVNKSSDYSGRYVPDVIKFVSADFRTISTSDSGPHWTNLRKG 140

Query: 391  LQSTTLHPRIISSHSQLQEKDVADLISSFEQEASLNNGIVKPVPKLRKLAIRVAGRLCFG 570
            LQ+  L P  +++  Q QEKD+  +    E+EA  N GIVKP+  L+K  +R+  RL FG
Sbjct: 141  LQNVALSPNSLAAQFQFQEKDIIKMTDILEREARNNKGIVKPLDHLKKATVRLISRLVFG 200

Query: 571  PESTMDDQFAEGIDWAIVEAIRLGDQARLVDMFEFTRYIPGLKPPYKELESLNQRVKEHI 750
            P    DDQ+ E +   I E I++   A+L + F + +Y+P  +   +  E   Q VK+ I
Sbjct: 201  PNFN-DDQYVEDMHNTIDELIQMSSYAQLAEAFYYAKYLPSHRKAVRHFEQTKQIVKKLI 259

Query: 751  SSYLSTHKPSSSSNCYLSFLLSQGFTEDILLANLFELFMFSVDSLAGTIAWALAFMIHHE 930
              Y+S   P    N YL FL SQ + E++++  +FE ++  VDS + T  WALAF+I   
Sbjct: 260  RPYISVSPP---PNTYLHFLQSQNYDEEVVIFAIFEAYLLGVDSTSSTTTWALAFLIREP 316

Query: 931  DVQQRVLKQVMN-KLGGTRKMVSVEDLTSTEMEYVHAVVKETXXXXXXXXXXXXXXXXXD 1107
            +VQ+++ +++ N      R+++ VED+   +++Y+ AV KET                 +
Sbjct: 317  NVQEKLYQELKNFAEQNDREIMKVEDI--NKLQYLQAVTKETMRMKPVAPLAIPHKACRE 374

Query: 1108 TELKGMTVKAGTLVLVNLYAVLHDERVWKEPEKFIPERFLMSASSGDAEEVKRMERSFVP 1287
            T L GM +  GT V+VN++++ H+E V+ +P  F+PERFL      D + VK ME+S++P
Sbjct: 375  TSLMGMPIDKGTKVMVNIHSLHHNENVFSDPFTFMPERFL----KVDNQNVKAMEQSYLP 430

Query: 1288 FAAGRRSCPAMELAK 1332
            F+AG R C  +EL K
Sbjct: 431  FSAGMRICAGIELGK 445


>dbj|BAG75114.1| cytochrome P450 [Eschscholzia californica]
          Length = 495

 Score =  305 bits (781), Expect = 3e-80
 Identities = 166/422 (39%), Positives = 248/422 (58%), Gaps = 1/422 (0%)
 Frame = +1

Query: 70   SKQRWPPGPMRFPLIGNLHQLRRGGQLVHLTLSKMAEKHGRIMTVWFGGPEPTIVVSDHE 249
            S   WP GP   P+IGN+H L  G + + + L  +A+ +G +MT+W G   P I+VSD E
Sbjct: 35   SNTEWPNGPKTLPIIGNMHLLG-GTKALQVILHNLAKVYGGVMTIWIGSWRPVIIVSDIE 93

Query: 250  VAWEVLVTKVNDYSARQLPVMSKITSADWHTLATSSLGPTWERFRKGLQSTTLHPRIISS 429
             AWEVLV K +DYSAR+LP + K  +A++ T+AT   GP W   RKGLQ+  L P  +++
Sbjct: 94   RAWEVLVNKSSDYSARELPEIIKYNAANFRTIATCDSGPHWSNLRKGLQNVALSPHNLAA 153

Query: 430  HSQLQEKDVADLISSFEQEASLNNGIVKPVPKLRKLAIRVAGRLCFGPESTMDDQFAEGI 609
              Q QEKD+  +I + E EA  NNGIV+P+  L+K  IR+  RL FG +   +D + E +
Sbjct: 154  QFQFQEKDITKMIQNLEVEAKNNNGIVQPLDHLKKATIRLISRLIFGQDFD-EDTYVEKL 212

Query: 610  DWAIVEAIRLGDQARLVDMFEFTRYIPGLKPPYKELESLNQRVKEHISSYLSTHKPSSSS 789
               I E IR+   A+L + F + RY+P  K          Q V   +  +LS + P   +
Sbjct: 213  HHTIDELIRMSGYAQLAEAFYYARYLPNHKKAVNHAAKTKQIVTHLMRPFLSLNPP---T 269

Query: 790  NCYLSFLLSQGFTEDILLANLFELFMFSVDSLAGTIAWALAFMIHHEDVQQRVLKQVMN- 966
            N YL FL SQ + E++++ ++FE+++  VDS + T AWALA+++   +VQ+ + +++ N 
Sbjct: 270  NSYLHFLQSQNYDEELIIFSIFEVYLLGVDSTSSTTAWALAYLVREPNVQETLYQELDNF 329

Query: 967  KLGGTRKMVSVEDLTSTEMEYVHAVVKETXXXXXXXXXXXXXXXXXDTELKGMTVKAGTL 1146
                 RK++ VED+   +++Y+ AV KET                 DT L G  V+ GT 
Sbjct: 330  AKQNDRKILKVEDI--NKLQYLQAVTKETMRMKPIAPLAIPHKASRDTTLMGKKVEKGTK 387

Query: 1147 VLVNLYAVLHDERVWKEPEKFIPERFLMSASSGDAEEVKRMERSFVPFAAGRRSCPAMEL 1326
            V+VNL+A+ H+E V+ +P KF+PERFL S     A   K ME+S++PF+AG R C  ME+
Sbjct: 388  VMVNLHALHHNENVFNDPYKFMPERFLKSYQGAKA---KAMEQSYLPFSAGMRICGGMEV 444

Query: 1327 AK 1332
             K
Sbjct: 445  GK 446


>gb|AGC29953.1| CYP719A23 [Sinopodophyllum hexandrum]
          Length = 489

 Score =  303 bits (776), Expect = 1e-79
 Identities = 170/443 (38%), Positives = 255/443 (57%)
 Frame = +1

Query: 4    MATVFLLGLLMKLLDQTFLIFGSKQRWPPGPMRFPLIGNLHQLRRGGQLVHLTLSKMAEK 183
            M++  +L L M L+        S  +WPPGP   P+IGNLHQL  GG  +H+ L+K+A  
Sbjct: 10   MSSTLILALAMALIFLFKAKSSSAIKWPPGPKTLPIIGNLHQL--GGDELHIVLAKLARV 67

Query: 184  HGRIMTVWFGGPEPTIVVSDHEVAWEVLVTKVNDYSARQLPVMSKITSADWHTLATSSLG 363
            HG IMT+W    +P IVVSD    WEVLV+K +DY+AR    +SKI SA  H++ TS  G
Sbjct: 68   HGAIMTIWMA-KKPVIVVSDVNSVWEVLVSKSSDYAARDAAEISKIVSASSHSINTSDSG 126

Query: 364  PTWERFRKGLQSTTLHPRIISSHSQLQEKDVADLISSFEQEASLNNGIVKPVPKLRKLAI 543
            P W+  R+GL    L P  IS+   +Q++D+  +I   +Q+A+ N GI+KP+  L++ + 
Sbjct: 127  PYWQTLRRGLTHGPLGPLNISAQIPIQQRDMQRVIREMQQDAAANGGIIKPLDHLKRSST 186

Query: 544  RVAGRLCFGPESTMDDQFAEGIDWAIVEAIRLGDQARLVDMFEFTRYIPGLKPPYKELES 723
            R+  RL FG ++  +D + + +   + +  R G  A L   F F +++P  K   KE   
Sbjct: 187  RLVSRLIFG-DTFDNDPYNDSMHEVVQDLNRFGGIALLEQAFSFAKHLPSYKRGVKEFHI 245

Query: 724  LNQRVKEHISSYLSTHKPSSSSNCYLSFLLSQGFTEDILLANLFELFMFSVDSLAGTIAW 903
              +++ + +   +++  P   SN YL FL SQ ++E+I++A +FEL++ ++DS A T  W
Sbjct: 246  HKRKIDDLVRPVVASANP--PSNSYLGFLQSQNYSEEIIIACIFELYLLAMDSSASTATW 303

Query: 904  ALAFMIHHEDVQQRVLKQVMNKLGGTRKMVSVEDLTSTEMEYVHAVVKETXXXXXXXXXX 1083
            ALAFMI  + VQ+++ + +   +G    +V  EDL  ++M Y+ AVVKET          
Sbjct: 304  ALAFMIRDQQVQEKLYQDIKRVIGDGVDLVKAEDL--SKMHYLQAVVKETMRMKPIAPLA 361

Query: 1084 XXXXXXXDTELKGMTVKAGTLVLVNLYAVLHDERVWKEPEKFIPERFLMSASSGDAEEVK 1263
                   DT + G  V  GT V+VNLYA+ HDE VW +P  F+PERFL      D + V 
Sbjct: 362  IPHKTAIDTTVMGTKVPKGTCVMVNLYALHHDESVWAKPYTFMPERFLQGE---DGKSV- 417

Query: 1264 RMERSFVPFAAGRRSCPAMELAK 1332
              E++F+PF AG R C  ME+ K
Sbjct: 418  -TEQAFLPFGAGMRICGGMEVGK 439


>dbj|BAF98471.1| cytochrome P450 [Coptis japonica var. dissecta]
          Length = 508

 Score =  300 bits (767), Expect = 1e-78
 Identities = 161/424 (37%), Positives = 246/424 (58%), Gaps = 3/424 (0%)
 Frame = +1

Query: 70   SKQRWPPGPMRFPLIGNLHQLRRGGQLVHLTLSKMAEKHGRIMTVWFGGPEPTIVVSDHE 249
            S+  WP GP + P+IGNLHQLR  G+L+H+TL+K+A+ HG +MT+W G   P IV+SD  
Sbjct: 45   SQMTWPSGPKKLPIIGNLHQLR--GELLHVTLAKLAKVHGGVMTIWMGSWVPIIVISDIN 102

Query: 250  VAWEVLVTKVNDYSARQLPVMSKI---TSADWHTLATSSLGPTWERFRKGLQSTTLHPRI 420
             AWEVLV K  DY AR++  + ++   ++   H +++S +GP W   RKGLQS  L P  
Sbjct: 103  SAWEVLVNKSADYGAREVTYLHELLRDSAMHPHNISSSDVGPLWHNIRKGLQSGALSPLS 162

Query: 421  ISSHSQLQEKDVADLISSFEQEASLNNGIVKPVPKLRKLAIRVAGRLCFGPESTMDDQFA 600
            ++S +Q +E+D+  ++    +E   NNG +KP+  ++    R+ GRL FGP S  D +F 
Sbjct: 163  VASQTQHRERDMKRVVHEMSREIVNNNGTIKPLVHIKNSTARLLGRLIFGP-SFNDSKFI 221

Query: 601  EGIDWAIVEAIRLGDQARLVDMFEFTRYIPGLKPPYKELESLNQRVKEHISSYLSTHKPS 780
            E + + I + IR      L + F + +Y+P  +   +E +    R++E +   LS+  P 
Sbjct: 222  ESMLYEIEDFIRTSSYTSLTNSFYYAKYLPSQRKATREAKLGKYRIEELVRPLLSSKPP- 280

Query: 781  SSSNCYLSFLLSQGFTEDILLANLFELFMFSVDSLAGTIAWALAFMIHHEDVQQRVLKQV 960
              +N YL FLLSQ  +E++ +  +FELF+  VDS + T  WALA+MI  ++ Q+++ + +
Sbjct: 281  --TNAYLYFLLSQNLSEEVTIFCIFELFLLGVDSASSTTTWALAYMIREQEAQEKLYQDI 338

Query: 961  MNKLGGTRKMVSVEDLTSTEMEYVHAVVKETXXXXXXXXXXXXXXXXXDTELKGMTVKAG 1140
               +G    +V +ED+   +++Y+ +VVKET                 DT L G  +  G
Sbjct: 339  RMTIGDV-DLVKIEDV--NKLKYLQSVVKETMRMKPIAPLALPHNAGKDTTLMGTKIVKG 395

Query: 1141 TLVLVNLYAVLHDERVWKEPEKFIPERFLMSASSGDAEEVKRMERSFVPFAAGRRSCPAM 1320
            T V+VNLYA+ H E VW EP KF+PER+L           K ME+S +PF AG R C  M
Sbjct: 396  TRVMVNLYALHHYEDVWLEPSKFMPERYLQGEDGSVTH--KAMEQSLLPFGAGMRICAGM 453

Query: 1321 ELAK 1332
            +L K
Sbjct: 454  DLGK 457