BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Cocculus22_contig00006521
         (2091 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gb|AAU20771.1| (S)-canadine synthase [Thalictrum flavum subsp. g...   425   e-116
sp|B5UAQ8.1|C7195_ESCCA RecName: Full=Cheilanthifoline synthase;...   412   e-112
gb|ADB89214.1| stylopine synthase [Papaver somniferum]                411   e-112
gb|AHF65153.1| stylopine synthase, partial [synthetic construct]      408   e-111
gb|AFI57927.1| cytochrome P450, partial [Papaver somniferum]          407   e-110
gb|AGL76711.1| (S)-canadine synthase, partial [Coptis chinensis]      404   e-110
dbj|BAF98470.1| cytochrome P450 [Coptis japonica var. dissecta]       404   e-109
sp|B1NF19.1|C719D_ARGME RecName: Full=(S)-stylopine synthase; Sh...   403   e-109
sp|Q948Y1.1|C719A_COPJA RecName: Full=(S)-canadine synthase; Alt...   402   e-109
gb|AFB74615.1| cytochrome P450 [Papaver somniferum]                   402   e-109
gb|AGC29953.1| CYP719A23 [Sinopodophyllum hexandrum]                  395   e-107
sp|B1NF20.1|C719E_ARGME RecName: Full=Cheilanthifoline synthase;...   395   e-107
sp|Q50LH4.1|C7193_ESCCA RecName: Full=(S)-stylopine synthase 2; ...   394   e-106
gb|ACO90219.1| stylopine synthase [Eschscholzia californica]          392   e-106
sp|Q50LH3.1|C7192_ESCCA RecName: Full=(S)-stylopine synthase 1; ...   391   e-106
dbj|BAG75116.1| cytochrome P450 [Eschscholzia californica]            391   e-106
gb|ADB89213.1| cheilanthifoline synthase [Papaver somniferum]         390   e-105
gb|AGC29954.1| CYP719A24 [Podophyllum peltatum]                       389   e-105
dbj|BAG75115.1| cytochrome P450 [Eschscholzia californica]            389   e-105
dbj|BAF98471.1| cytochrome P450 [Coptis japonica var. dissecta]       387   e-104

>gb|AAU20771.1| (S)-canadine synthase [Thalictrum flavum subsp. glaucum]
          Length = 492

 Score =  425 bits (1093), Expect = e-116
 Identities = 218/501 (43%), Positives = 326/501 (65%), Gaps = 2/501 (0%)
 Frame = -1

Query: 1569 MEVSSLWITVATVFLLGLLMKLLDQTFFRTS-SKQQWPPGPTKLPLIGNLHQLNRGGELL 1393
            ME+ SLW+  AT+ L+  +  L+      +S S+ +WP GP KLP+IGNLHQL  GG++L
Sbjct: 1    MELVSLWLVSATLALVVAITILIPMVTSSSSFSQMKWPTGPNKLPIIGNLHQL--GGDVL 58

Query: 1392 HVVLSKMAQKYGGIMTVWFSGQQPSIVVSDHDVAWEVMVTKASDYSSRVLPSITRFTTAD 1213
            HV L+K+AQ +G +MTVW    +P IV+SD D AWEV+V K+SDY +R +P IT+  +A 
Sbjct: 59   HVALAKLAQVHGSVMTVWIGNWRPIIVISDIDKAWEVLVNKSSDYGARDMPEITKIASAS 118

Query: 1212 WRTLATSNLGPYWQTLRKGLHSNVINPQTISSQTQLQEKDIADLISSFEQEASSNDGVVE 1033
            W T++TS+ G +WQT+RKGL S  + P  I++Q+Q QE+D+  LI +   EA+ N+ +V+
Sbjct: 119  WHTISTSDAGAFWQTVRKGLQSGAMGPLNIAAQSQFQERDMKRLIQALRDEAAQNNNIVK 178

Query: 1032 PMPXXXXXXXXXIARFCFGPEFLTDEHFVERMDCAVEDEINLSGHTSLVDMFEFIRFIPG 853
            P+          + R  FG  F  D+ FVE M   ++D I +SG+  L + F + +++P 
Sbjct: 179  PLDHIKKNTVRLLTRLIFGQTF-DDDKFVESMHFEIDDIIRISGYARLAEAFYYAKYLPS 237

Query: 852  FGRPFKEAENLKQRIMELISPYLSTHKPSSPNCYLSFLLSQGLSEEVVICNLFELFVLAI 673
              +  +EA  +K R+ +L+SP LS++ P+  N YL FLLSQ  SEEV+I  +FEL++L +
Sbjct: 238  HKKAEREAYLVKCRVEDLVSPLLSSNPPT--NSYLYFLLSQRFSEEVIIFCIFELYLLGV 295

Query: 672  DSTSTAITWALAFMIHNGEIQERVLKEVMKKGLXXXXXXXXXXXXXEMEYVHALVKETLR 493
            DSTS+  TWALA++I    IQE++ ++   +               +++Y+ A+VKET+R
Sbjct: 296  DSTSSTTTWALAYLIREQAIQEKLYQDT--RMTLGDVDLVKIEDVSKLKYLQAVVKETMR 353

Query: 492  MRPVAPLG-PHGAARDSELKGMKVREGTPVWVNLYAMLHDERVWKEPNRFMPERFLVGSG 316
            M+P+APL  PH  A+D+ L G KV +GT + VNLYA+ H++ +W  P +FMPERFL G  
Sbjct: 354  MKPIAPLAIPHKTAKDTTLMGSKVAKGTRIMVNLYALHHNQNIWTNPYKFMPERFLQGED 413

Query: 315  ASGDRDDVWAMERSFVAFGAGRRNCGGMELAKIQVAVTVANLVNSFEWCSAVEGQLPDLS 136
             S       AME+SF+ F AG R C GM+L K+Q A  +ANLVN+F+W    EG+ PD+S
Sbjct: 414  GSASNK---AMEQSFLPFSAGMRICAGMDLGKLQFAFALANLVNAFKWSCVEEGKFPDMS 470

Query: 135  QDLTPLLVMKTPLVARVVPRR 73
            ++L+ +L+MKTPL A++  R+
Sbjct: 471  EELSFVLLMKTPLEAKITARK 491


>sp|B5UAQ8.1|C7195_ESCCA RecName: Full=Cheilanthifoline synthase; Short=CHS; AltName:
            Full=Cytochrome P450 719A5 gi|209571368|dbj|BAG75113.1|
            cheilanthifoline synthase [Eschscholzia californica]
          Length = 490

 Score =  412 bits (1058), Expect = e-112
 Identities = 207/495 (41%), Positives = 319/495 (64%), Gaps = 1/495 (0%)
 Frame = -1

Query: 1557 SLWITVATVFLLGLLMKLLDQTFFRTSSKQQWPPGPTKLPLIGNLHQLNRGGELLHVVLS 1378
            SLW+  ATV ++  + KLL ++   + S  +WP GP KLP+IGNLHQL  GGE  HVVL+
Sbjct: 4    SLWVVTATVVVVFAIAKLLKKS--SSISTMEWPKGPKKLPIIGNLHQL--GGEAFHVVLA 59

Query: 1377 KMAQKYGGIMTVWFSGQQPSIVVSDHDVAWEVMVTKASDYSSRVLPSITRFTTADWRTLA 1198
             +A+ +G +MT+W    +P IV+SD D AWEV+V K+SDY+ R  P IT+  +A+W+ ++
Sbjct: 60   NLAKIHGTVMTIWVGAWRPMIVISDIDKAWEVLVNKSSDYAGRDFPEITKIISANWKNIS 119

Query: 1197 TSNLGPYWQTLRKGLHSNVINPQTISSQTQLQEKDIADLISSFEQEASSNDGVVEPMPXX 1018
             S+ GP+WQ LRKGL    + P  + SQ QLQE+D+ +LI+S +++AS N+G+++P+   
Sbjct: 120  CSDSGPFWQNLRKGLQGGALAPLNVISQYQLQERDMKNLITSMQEKASKNNGILKPLDYL 179

Query: 1017 XXXXXXXIARFCFGPEFLTDEHFVERMDCAVEDEINLSGHTSLVDMFEFIRFIPGFGRPF 838
                   ++R  FG  F  DE+FV+ +  A++D + +SG+ SL D F+F   +P   +  
Sbjct: 180  KEETIRLLSRLIFGQSF-NDENFVKGVHLALDDLVRISGYASLADAFKFCENLPSHKKSI 238

Query: 837  KEAENLKQRIMELISPYLSTHKPSSPNCYLSFLLSQGLSEEVVICNLFELFVLAIDSTST 658
            +E   + +R++ L+ PYL  + P+  N YL FL SQ  S+EV+I  + E++ L +DST++
Sbjct: 239  REVHEVNERVVNLVKPYLVKNPPT--NTYLYFLNSQKFSDEVIISAVLEVYDLGVDSTAS 296

Query: 657  AITWALAFMIHNGEIQERVLKEVMKKGLXXXXXXXXXXXXXEMEYVHALVKETLRMRPVA 478
               WAL F++    +QE++ KE++   L             ++ Y+ A++KET+RM+P+A
Sbjct: 297  TAVWALTFLVREPRVQEKLYKEII--DLTGGERSVKVEDVSKLPYLQAVMKETMRMKPIA 354

Query: 477  PLG-PHGAARDSELKGMKVREGTPVWVNLYAMLHDERVWKEPNRFMPERFLVGSGASGDR 301
            P+  PH  +RD+ L G KV +GT + VNLYA+ H+ +V+ EP +F+PERFL   G     
Sbjct: 355  PMAIPHKTSRDTSLMGKKVNKGTSIMVNLYAIHHNPKVFPEPYKFIPERFL--QGQESKY 412

Query: 300  DDVWAMERSFVAFGAGRRNCGGMELAKIQVAVTVANLVNSFEWCSAVEGQLPDLSQDLTP 121
             D+  ME+S + F AG R C GMEL K+Q   ++A+LV +F+W  AV+G+LPDLS+D   
Sbjct: 413  GDIKEMEQSLLPFSAGMRICAGMELGKLQYGFSLASLVEAFKWTCAVDGKLPDLSEDHCF 472

Query: 120  LLVMKTPLVARVVPR 76
            +L+MK PL AR+ PR
Sbjct: 473  ILLMKNPLEARITPR 487


>gb|ADB89214.1| stylopine synthase [Papaver somniferum]
          Length = 494

 Score =  411 bits (1057), Expect = e-112
 Identities = 210/496 (42%), Positives = 316/496 (63%), Gaps = 1/496 (0%)
 Frame = -1

Query: 1560 SSLWITVATVFLLGLLMKLLDQTFFRTSSKQQWPPGPTKLPLIGNLHQLNRGGELLHVVL 1381
            S+ WI   +  ++  ++ +L     + SS   WP GP  LP+IGN+H L  GG  L VVL
Sbjct: 7    SNPWILTTSTLVVITIITMLMVFKRKKSSTMVWPTGPKTLPIIGNMHVL--GGTALQVVL 64

Query: 1380 SKMAQKYGGIMTVWFSGQQPSIVVSDHDVAWEVMVTKASDYSSRVLPSITRFTTADWRTL 1201
              +A+ +G +MT+W    +P IVVSD D AWEV+V K+SDYS+R +P IT+  +ADW+T+
Sbjct: 65   HNLAKIHGNVMTIWIGSWRPVIVVSDIDRAWEVLVNKSSDYSARDMPEITKIISADWKTI 124

Query: 1200 ATSNLGPYWQTLRKGLHSNVINPQTISSQTQLQEKDIADLISSFEQEASSNDGVVEPMPX 1021
            +TS+ GP W  LRKGL +  ++P  +++Q+Q QEKDI  +I S ++EA+SN+G+V+P+  
Sbjct: 125  STSDSGPGWSNLRKGLQNVALSPHNLAAQSQFQEKDITKMIQSLKKEAASNNGIVKPIDH 184

Query: 1020 XXXXXXXXIARFCFGPEFLTDEHFVERMDCAVEDEINLSGHTSLVDMFEFIRFIPGFGRP 841
                    I+R  FG +F  D+ +V+ M  A+E+ I +SG+  L + F + +++P   + 
Sbjct: 185  LKKATLRLISRLIFGQDF-DDDKYVDDMHHAIEELIRVSGYAQLAEAFYYAKYLPSHKKA 243

Query: 840  FKEAENLKQRIMELISPYLSTHKPSSPNCYLSFLLSQGLSEEVVICNLFELFVLAIDSTS 661
             ++ E   QR+ +L+ P+LS + P+  N YL FL SQ   EEV+I  +FE ++L +DSTS
Sbjct: 244  VRDVEEANQRVKKLVRPFLSLNPPT--NTYLHFLNSQKYDEEVIIFAIFEAYLLGVDSTS 301

Query: 660  TAITWALAFMIHNGEIQERVLKEVMKKGLXXXXXXXXXXXXXEMEYVHALVKETLRMRPV 481
                WALAF+I    +Q+++ +E+                  +++Y+ A++KET+RM+P+
Sbjct: 302  LTTAWALAFLIREPVVQDKLYQELKNLTAKNDCEIVKVEDLNKLQYLQAVLKETMRMKPI 361

Query: 480  APLG-PHGAARDSELKGMKVREGTPVWVNLYAMLHDERVWKEPNRFMPERFLVGSGASGD 304
            APL  PH A RD+ LKG K+ +GT V VN+YA+ H+E+VWKEP +FMPERFL        
Sbjct: 362  APLAIPHKACRDTSLKGNKIDQGTQVMVNIYALHHNEKVWKEPFKFMPERFLQTQDVVNG 421

Query: 303  RDDVWAMERSFVAFGAGRRNCGGMELAKIQVAVTVANLVNSFEWCSAVEGQLPDLSQDLT 124
            +     ME+S + F AG R C GMEL K+Q + ++ANLVN+FEW    +G LPD+S  L 
Sbjct: 422  K----GMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVNAFEWSCVSDGVLPDMSDQLG 477

Query: 123  PLLVMKTPLVARVVPR 76
             +L+MKTPL AR+VPR
Sbjct: 478  FVLLMKTPLQARIVPR 493


>gb|AHF65153.1| stylopine synthase, partial [synthetic construct]
          Length = 511

 Score =  408 bits (1048), Expect = e-111
 Identities = 206/471 (43%), Positives = 305/471 (64%), Gaps = 1/471 (0%)
 Frame = -1

Query: 1485 RTSSKQQWPPGPTKLPLIGNLHQLNRGGELLHVVLSKMAQKYGGIMTVWFSGQQPSIVVS 1306
            + SS   WP GP  LP+IGN+H L  GG  L VVL  +A+ +G +MT+W    +P IVVS
Sbjct: 46   KKSSTMVWPTGPKTLPIIGNMHVL--GGTALQVVLHNLAKIHGNVMTIWIGSWRPVIVVS 103

Query: 1305 DHDVAWEVMVTKASDYSSRVLPSITRFTTADWRTLATSNLGPYWQTLRKGLHSNVINPQT 1126
            D D AWEV+V K+SDYS+R +P IT+  +ADW+T++TS+ GP W  LRKGL +  ++P  
Sbjct: 104  DIDRAWEVLVNKSSDYSARDMPEITKIISADWKTISTSDSGPGWSNLRKGLQNVALSPHN 163

Query: 1125 ISSQTQLQEKDIADLISSFEQEASSNDGVVEPMPXXXXXXXXXIARFCFGPEFLTDEHFV 946
            +++Q+Q QEKDI  +I S ++EA+SN+G+V+P+          I+R  FG +F  D+ +V
Sbjct: 164  LAAQSQFQEKDITKMIQSLKKEAASNNGIVKPIDHLKKATLRLISRLIFGQDF-DDDKYV 222

Query: 945  ERMDCAVEDEINLSGHTSLVDMFEFIRFIPGFGRPFKEAENLKQRIMELISPYLSTHKPS 766
            + M  A+E+ I +SG+  L + F + +++P   +  ++ E   QR+ +L+ P+LS + P+
Sbjct: 223  DDMHHAIEELIRVSGYAQLAEAFYYAKYLPSHKKAVRDVEEANQRVKKLVRPFLSLNPPT 282

Query: 765  SPNCYLSFLLSQGLSEEVVICNLFELFVLAIDSTSTAITWALAFMIHNGEIQERVLKEVM 586
              N YL FL SQ   EEV+I  +FE ++L +DSTS    WALAF+I    +Q+++ +E+ 
Sbjct: 283  --NTYLHFLNSQKYDEEVIIFAIFEAYLLGVDSTSLTTAWALAFLIREPVVQDKLYQELK 340

Query: 585  KKGLXXXXXXXXXXXXXEMEYVHALVKETLRMRPVAPLG-PHGAARDSELKGMKVREGTP 409
                             +++Y+ A++KET+RM+P+APL  PH A RD+ LKG K+ +GT 
Sbjct: 341  NLTAKNDCEIVKVEDLNKLQYLQAVLKETMRMKPIAPLAIPHKACRDTSLKGNKIDQGTQ 400

Query: 408  VWVNLYAMLHDERVWKEPNRFMPERFLVGSGASGDRDDVWAMERSFVAFGAGRRNCGGME 229
            V VN+YA+ H+E+VWKEP +FMPERFL        +     ME+S + F AG R C GME
Sbjct: 401  VMVNIYALHHNEKVWKEPFKFMPERFLQTQDVVNGK----GMEQSLLPFSAGMRICAGME 456

Query: 228  LAKIQVAVTVANLVNSFEWCSAVEGQLPDLSQDLTPLLVMKTPLVARVVPR 76
            L K+Q + ++ANLVN+FEW    +G LPD+S  L  +L+MKTPL AR+VPR
Sbjct: 457  LGKLQFSFSLANLVNAFEWSCVSDGVLPDMSDQLGFVLLMKTPLQARIVPR 507


>gb|AFI57927.1| cytochrome P450, partial [Papaver somniferum]
          Length = 488

 Score =  407 bits (1045), Expect = e-110
 Identities = 219/502 (43%), Positives = 318/502 (63%), Gaps = 4/502 (0%)
 Frame = -1

Query: 1569 MEVSSLWITVATVFLLGLLMKLLDQTFFR---TSSKQQWPPGPTKLPLIGNLHQLNRGGE 1399
            M +S+LWI      +L +   +L    FR   ++S  +WP GP  LP+IGNLH L  GG 
Sbjct: 1    MIMSNLWILTLISTILAVFAAVL--IIFRRRISASTTEWPVGPKTLPIIGNLHIL--GGT 56

Query: 1398 LLHVVLSKMAQKYGGIMTVWFSGQQPSIVVSDHDVAWEVMVTKASDYSSRVLPSITRFTT 1219
             LHVVL K+A+ YG +MT+W    +P I+VSD D AWEV+V K+SDYS+R +P IT+  T
Sbjct: 57   ALHVVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGT 116

Query: 1218 ADWRTLATSNLGPYWQTLRKGLHSNVINPQTISSQTQLQEKDIADLISSFEQEASSNDGV 1039
            A+WRT+++S+ GP+W TLRKGL S  ++PQ ++SQT  QE+DI  LI + + EA+ N G+
Sbjct: 117  ANWRTISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAALNSGM 176

Query: 1038 VEPMPXXXXXXXXXIARFCFGPEFLTDEHFVERMDCAVEDEINLSGHTSLVDMFEFIRFI 859
            V+P+          I+R  +G +F  D+ +VE M   +E  I +SG+  L ++F + +++
Sbjct: 177  VKPLDHLKKATVRLISRLIYGQDF-DDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYL 235

Query: 858  PGFGRPFKEAENLKQRIMELISPYLSTHKPSSPNCYLSFLLSQGLSEEVVICNLFELFVL 679
            P   R    AE  K+R++ L+ P+L ++   + N YL FL SQ   EEV+I  +FE ++L
Sbjct: 236  PSHKRAVTGAEEAKRRVIALVRPFLQSN--PATNTYLHFLKSQLYPEEVIIFAIFEAYLL 293

Query: 678  AIDSTSTAITWALAFMIHNGEIQERVLKEVMKKGLXXXXXXXXXXXXXEMEYVHALVKET 499
             +DSTS+   WALAF+I    +QE++ +E+                  ++ Y+ A+VKET
Sbjct: 294  GVDSTSSTTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKET 353

Query: 498  LRMRPVAPLG-PHGAARDSELKGMKVREGTPVWVNLYAMLHDERVWKEPNRFMPERFLVG 322
            +RM+P+APL  PH A +D+ L G KV +GT V VN++A+ H E+VWKEP +FMPERFL  
Sbjct: 354  MRMKPIAPLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFMPERFL-- 411

Query: 321  SGASGDRDDVWAMERSFVAFGAGRRNCGGMELAKIQVAVTVANLVNSFEWCSAVEGQLPD 142
                 D+    AME+S + F AG R C GMEL K+Q + ++ANLVN+F+W    +G LPD
Sbjct: 412  --QKHDK----AMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPD 465

Query: 141  LSQDLTPLLVMKTPLVARVVPR 76
            +S  L  +L MKTPL AR+VPR
Sbjct: 466  MSDLLGFVLFMKTPLEARIVPR 487


>gb|AGL76711.1| (S)-canadine synthase, partial [Coptis chinensis]
          Length = 491

 Score =  404 bits (1039), Expect = e-110
 Identities = 211/503 (41%), Positives = 323/503 (64%), Gaps = 5/503 (0%)
 Frame = -1

Query: 1569 MEVSSLWI--TVATVFLLGLLMKLLDQTFFRTSSKQQ--WPPGPTKLPLIGNLHQLNRGG 1402
            ME+S L +  TVA VF    ++++L    F +SS  Q  WP GP KLP+IGNLHQL  G 
Sbjct: 1    MEMSPLLVCATVAIVFATTTIIRIL----FSSSSLPQMKWPSGPRKLPIIGNLHQL--GD 54

Query: 1401 ELLHVVLSKMAQKYGGIMTVWFSGQQPSIVVSDHDVAWEVMVTKASDYSSRVLPSITRFT 1222
            ++LHV L+K+A+ +G +MT+W    +P IV+SD + AWEV+V K++DY +R +P IT+  
Sbjct: 55   DVLHVALAKLAKVHGSMMTIWIGSWRPVIVISDLEKAWEVLVNKSADYGARDMPEITKIA 114

Query: 1221 TADWRTLATSNLGPYWQTLRKGLHSNVINPQTISSQTQLQEKDIADLISSFEQEASSNDG 1042
            +A W T++TS+ GP+WQ +RKGL S  + P  +++Q Q QE+ +  LI +   EA++N+G
Sbjct: 115  SASWHTISTSDAGPFWQNVRKGLQSGAMGPFNVAAQNQHQERGMKRLIKAMSDEAANNNG 174

Query: 1041 VVEPMPXXXXXXXXXIARFCFGPEFLTDEHFVERMDCAVEDEINLSGHTSLVDMFEFIRF 862
            +V+P+          + R  FG  F  D  F+E M   +ED I +SG+  L + F + ++
Sbjct: 175  IVKPLDHIKKNTVRLLTRLIFGQNF-DDNKFIESMHYEIEDIIRISGYARLAEAFYYAKY 233

Query: 861  IPGFGRPFKEAENLKQRIMELISPYLSTHKPSSPNCYLSFLLSQGLSEEVVICNLFELFV 682
            +P   +  +EA  +K R+ EL+ P LS++ P+  N YL FLLSQ   EEV+I  +FEL++
Sbjct: 234  LPSHKKAEREAFLVKCRVQELVRPLLSSNPPT--NSYLYFLLSQNFEEEVIIFCIFELYL 291

Query: 681  LAIDSTSTAITWALAFMIHNGEIQERVLKEVMKKGLXXXXXXXXXXXXXEMEYVHALVKE 502
            L +DSTS+  TWALA++I     QE++ +++  +               +++Y+  +VKE
Sbjct: 292  LGVDSTSSTTTWALAYLIREQGAQEKLYQDI--RMTLGDVDLVKIEDVNKLKYLQGVVKE 349

Query: 501  TLRMRPVAPLG-PHGAARDSELKGMKVREGTPVWVNLYAMLHDERVWKEPNRFMPERFLV 325
            T+RM+P+APL  PH  A+++ L G KV +GT + VNLYA+ H++ +W +P +FMPERFL 
Sbjct: 350  TMRMKPIAPLAIPHKTAKETTLMGTKVAKGTRIMVNLYALHHNQNIWPDPYKFMPERFLE 409

Query: 324  GSGASGDRDDVWAMERSFVAFGAGRRNCGGMELAKIQVAVTVANLVNSFEWCSAVEGQLP 145
            G+  +       AME+SF+ F AG R C GM+L K+Q A  +ANLVN+F+W    EG+LP
Sbjct: 410  GATGTAYNK---AMEQSFLPFSAGMRICAGMDLGKLQFAFALANLVNAFKWSCVEEGKLP 466

Query: 144  DLSQDLTPLLVMKTPLVARVVPR 76
            D+ ++L+ +L+MKTPL AR+  R
Sbjct: 467  DMGEELSFVLLMKTPLEARIAGR 489


>dbj|BAF98470.1| cytochrome P450 [Coptis japonica var. dissecta]
          Length = 491

 Score =  404 bits (1037), Expect = e-109
 Identities = 206/500 (41%), Positives = 320/500 (64%), Gaps = 1/500 (0%)
 Frame = -1

Query: 1569 MEVSSLWITVATVFLLGLLMKLLDQTFFRTSSKQQWPPGPTKLPLIGNLHQLNRGGELLH 1390
            ME S LW+  +TV ++ ++  ++  +   +SSK++WP GP +LP+IGNLH L  GG+LLH
Sbjct: 1    MEGSFLWLIGSTVAIVLVITTIVRMSSSSSSSKKKWPSGPKRLPIIGNLHLL--GGDLLH 58

Query: 1389 VVLSKMAQKYGGIMTVWFSGQQPSIVVSDHDVAWEVMVTKASDYSSRVLPSITRFTTADW 1210
            V L+K+A+ +G +MT+W    +P IV+SD + AWEV+V+K+++Y  R  P I +  T   
Sbjct: 59   VTLAKLAKVHGSVMTIWIGRWRPIIVISDINSAWEVLVSKSAEYGQRDTPDIFKTLTVGQ 118

Query: 1209 RTLATSNLGPYWQTLRKGLHSNVINPQTISSQTQLQEKDIADLISSFEQEASSNDGVVEP 1030
              ++ S++GP+W  +RKGL +  ++P  +++QTQ +E+D+  LI    +EA + +G+++P
Sbjct: 119  NNISMSDIGPFWHNVRKGLQNGALSPLNVAAQTQFREEDVKRLIHEMSREALNKNGIIKP 178

Query: 1029 MPXXXXXXXXXIARFCFGPEFLTDEHFVERMDCAVEDEINLSGHTSLVDMFEFIRFIPGF 850
            +          + R  FGP F  D+ FVE +   +ED + LSG+  L + F + +++P  
Sbjct: 179  LDHMKKNTARLLGRLIFGPTFDNDK-FVESVLYEIEDVLRLSGYARLTEAFYYAKYLPSQ 237

Query: 849  GRPFKEAENLKQRIMELISPYLSTHKPSSPNCYLSFLLSQGLSEEVVICNLFELFVLAID 670
             +  +EA   K RI EL+ P LS++ P+  N YL FL SQ  S+E++I   FELF+L +D
Sbjct: 238  KKVAREAYLAKYRIEELMRPLLSSNPPT--NSYLYFLQSQNYSKEIIIFCTFELFLLGVD 295

Query: 669  STSTAITWALAFMIHNGEIQERVLKEVMKKGLXXXXXXXXXXXXXEMEYVHALVKETLRM 490
            STS+  TWALA++IH   +QE++ +++  +               +++Y+ A+VKET+RM
Sbjct: 296  STSSTATWALAYLIHEQAVQEKLNEDI--RMTIGDVDLVKIEDLSKLKYLQAVVKETMRM 353

Query: 489  RPVAPLG-PHGAARDSELKGMKVREGTPVWVNLYAMLHDERVWKEPNRFMPERFLVGSGA 313
            +P+APL  PH  A D+ L G KV  GT + VNLYA+ H+E +W EP +FMPERFL G   
Sbjct: 354  KPIAPLAIPHKTANDTTLMGTKVARGTQIMVNLYALHHNEDIWPEPYKFMPERFLQGENV 413

Query: 312  SGDRDDVWAMERSFVAFGAGRRNCGGMELAKIQVAVTVANLVNSFEWCSAVEGQLPDLSQ 133
            S +     AME+SF+ FGAG R C GM+L K+Q+A  +ANLVN+F+W    EG+LPD+S+
Sbjct: 414  SANNK---AMEQSFLPFGAGMRICAGMDLGKLQIAFALANLVNAFKWSCVDEGKLPDMSE 470

Query: 132  DLTPLLVMKTPLVARVVPRR 73
             L  + +MKTPL  R+  R+
Sbjct: 471  QLFAVTLMKTPLEGRISTRK 490


>sp|B1NF19.1|C719D_ARGME RecName: Full=(S)-stylopine synthase; Short=STS; AltName:
            Full=Cytochrome P450 719A13 gi|148841092|gb|ABR14721.1|
            stylopine synthase [Argemone mexicana]
          Length = 504

 Score =  403 bits (1036), Expect = e-109
 Identities = 214/506 (42%), Positives = 314/506 (62%), Gaps = 8/506 (1%)
 Frame = -1

Query: 1569 MEVSSLWI-TVATVFLLGLLMKLLDQTFF------RTSSKQQWPPGPTKLPLIGNLHQLN 1411
            M  +S WI T +T     +L+ LL   F        +SSK  WP GP  LP+IGN++ L 
Sbjct: 6    MTNNSPWILTSSTTTTTTILLSLLFTIFIILRRNKSSSSKMVWPTGPKTLPIIGNMNIL- 64

Query: 1410 RGGELLHVVLSKMAQKYGGIMTVWFSGQQPSIVVSDHDVAWEVMVTKASDYSSRVLPSIT 1231
             GG  LHVVL  +A+ YG +MT+W    +P IVVSD D AWEV+V K+SDYS+R +P IT
Sbjct: 65   -GGTALHVVLHNLAKTYGNVMTIWIGSWRPVIVVSDIDRAWEVLVNKSSDYSARDMPEIT 123

Query: 1230 RFTTADWRTLATSNLGPYWQTLRKGLHSNVINPQTISSQTQLQEKDIADLISSFEQEASS 1051
            +  TADW+T+++S+ GP+W  LRKGL +  ++PQ +SSQ++ QE+DI   I + ++EA  
Sbjct: 124  KLATADWKTISSSDSGPFWTNLRKGLQNVALSPQNLSSQSKFQERDIIKTIQNLKEEAKM 183

Query: 1050 NDGVVEPMPXXXXXXXXXIARFCFGPEFLTDEHFVERMDCAVEDEINLSGHTSLVDMFEF 871
            N+G+V+P+          I+R  +G +F  DE +VE M   +E+ I +SG+  L + F +
Sbjct: 184  NNGIVKPLDHLKKAMVRLISRLIYGQDFDNDE-YVEEMHHTIEELIRVSGYARLAEAFYY 242

Query: 870  IRFIPGFGRPFKEAENLKQRIMELISPYLSTHKPSSPNCYLSFLLSQGLSEEVVICNLFE 691
             +++P   +  +E     QR+  L+ P LS + P+  N YL FL SQ   +EV+I  +FE
Sbjct: 243  AKYLPSHKKAVREVLQANQRVQNLVRPLLSLNSPT--NTYLHFLRSQNYEDEVIIFAIFE 300

Query: 690  LFVLAIDSTSTAITWALAFMIHNGEIQERVLKEVMKKGLXXXXXXXXXXXXXEMEYVHAL 511
             ++L +DSTS+   WALA++I    +QE++ +E+                  +++Y+ A+
Sbjct: 301  AYLLGVDSTSSTTAWALAYLIREPNVQEKLYEELKNFTNDNDRKMVKFEDLNKLQYLQAV 360

Query: 510  VKETLRMRPVAPLG-PHGAARDSELKGMKVREGTPVWVNLYAMLHDERVWKEPNRFMPER 334
            VKET+RM+P+APL  PH A R++ L G KV +GT V VN+YA+ H++ VWKEP +F PER
Sbjct: 361  VKETMRMKPIAPLAIPHKACRETSLMGRKVNQGTRVMVNIYALHHNQNVWKEPYKFNPER 420

Query: 333  FLVGSGASGDRDDVWAMERSFVAFGAGRRNCGGMELAKIQVAVTVANLVNSFEWCSAVEG 154
            FL     + D  D  AME+S + F AG R C GMEL K+Q +  +ANLVN+F+W    +G
Sbjct: 421  FL---QKNQDGVDGKAMEQSLLPFSAGMRICAGMELGKLQFSFALANLVNAFKWSCVSDG 477

Query: 153  QLPDLSQDLTPLLVMKTPLVARVVPR 76
              PD+S  L  +L+MKTPL A +VPR
Sbjct: 478  VFPDMSDQLGFVLLMKTPLEAGIVPR 503


>sp|Q948Y1.1|C719A_COPJA RecName: Full=(S)-canadine synthase; AltName:
            Full=(S)-tetrahydrocolumbamine oxidase
            (methylenedioxy-bridge-forming); AltName: Full=Cytochrome
            P450 719A1 gi|15822820|dbj|BAB68769.1| methylenedioxy
            bridge-forming enzyme [Coptis japonica]
          Length = 491

 Score =  402 bits (1034), Expect = e-109
 Identities = 211/504 (41%), Positives = 325/504 (64%), Gaps = 6/504 (1%)
 Frame = -1

Query: 1569 MEVSSLWI--TVATVFLLGLLMKLLDQTFFRTSSKQQ--WPPGPTKLPLIGNLHQLNRGG 1402
            ME++ L +  TVA VF    ++++L    F +SS  Q  WP GP KLP+IGNLHQL  G 
Sbjct: 1    MEMNPLLVCATVAIVFATTTIIRIL----FSSSSLPQMKWPSGPRKLPIIGNLHQL--GD 54

Query: 1401 ELLHVVLSKMAQKYGGIMTVWFSGQQPSIVVSDHDVAWEVMVTKASDYSSRVLPSITRFT 1222
            ++LHV L+K+A+ +G +MT+W    +P IV+SD + AWEV+V K++DY +R +P IT+  
Sbjct: 55   DVLHVALAKLAKVHGSVMTIWIGSWRPVIVISDIEKAWEVLVNKSADYGARDMPEITKIA 114

Query: 1221 TADWRTLATSNLGPYWQTLRKGLHSNVINPQTISSQTQLQEKDIADLISSFEQEASSNDG 1042
            +A W T++TS+ G +WQ +RKGL S  + P  +++Q Q QE+D+  LI +   EA++N+G
Sbjct: 115  SASWHTISTSDAGSFWQNVRKGLQSGAMGPLNVAAQNQYQERDMKRLIKAMSDEAANNNG 174

Query: 1041 VVEPMPXXXXXXXXXIARFCFGPEFLTDEHFVERMDCAVEDEINLSGHTSLVDMFEFIRF 862
            +V+P+          + R  FG  F  D  F+E M   +ED I +SG+  L + F + ++
Sbjct: 175  IVKPLDHIKKNTVRLLTRLIFGQAF-DDNKFIESMHYEIEDIIRISGYARLAEAFYYAKY 233

Query: 861  IPGFGRPFKEAENLKQRIMELISPYLSTHKPSSPNCYLSFLLSQGLSEEVVICNLFELFV 682
            +P   +  +EA  +K R+ EL+ P LS+  P+  N YL FLLSQ   EEV+I  +FEL++
Sbjct: 234  LPSHKKAEREAFLVKCRVEELVRPLLSSKPPT--NSYLYFLLSQNFEEEVIIFCIFELYL 291

Query: 681  LAIDSTSTAITWALAFMIHNGEIQERVLKEVMKKGLXXXXXXXXXXXXXEMEYVHALVKE 502
            L +DSTS+  TWALA++I     QE++ +++  +               +++Y+  +VKE
Sbjct: 292  LGVDSTSSTTTWALAYLIREQGAQEKLYQDI--RMTLGDVDLVKIEDVNKLKYLQGVVKE 349

Query: 501  TLRMRPVAPLG-PHGAARDSELKGMKVREGTPVWVNLYAMLHDERVWKEPNRFMPERFLV 325
            T+RM+P+APL  PH  A+++ L G KV +GT + VNLYA+ H++ +W +P +FMPERFL 
Sbjct: 350  TMRMKPIAPLAIPHKTAKETTLMGTKVAKGTRIMVNLYALHHNQNIWPDPYKFMPERFLE 409

Query: 324  G-SGASGDRDDVWAMERSFVAFGAGRRNCGGMELAKIQVAVTVANLVNSFEWCSAVEGQL 148
            G +G + ++    AME+SF+ F AG R C GM+L K+Q A  +ANLVN+F+W    EG+L
Sbjct: 410  GETGTAYNK----AMEQSFLPFSAGMRICAGMDLGKLQFAFALANLVNAFKWSCVEEGKL 465

Query: 147  PDLSQDLTPLLVMKTPLVARVVPR 76
            PD+ ++L+ +L+MKTPL AR+  R
Sbjct: 466  PDMGEELSFVLLMKTPLEARIAGR 489


>gb|AFB74615.1| cytochrome P450 [Papaver somniferum]
          Length = 486

 Score =  402 bits (1034), Expect = e-109
 Identities = 219/502 (43%), Positives = 319/502 (63%), Gaps = 4/502 (0%)
 Frame = -1

Query: 1569 MEVSSLWITVATVFLLGLLMKLLDQTFFR---TSSKQQWPPGPTKLPLIGNLHQLNRGGE 1399
            M +S+LWI      +L +   +L    FR   ++S  +WP GP  LP+IGNLH L  GG 
Sbjct: 1    MIMSNLWILTLISTILAVFAAVL--IIFRRRISASTTEWPVGPKTLPIIGNLHIL--GGT 56

Query: 1398 LLHVVLSKMAQKYGGIMTVWFSGQQPSIVVSDHDVAWEVMVTKASDYSSRVLPSITRFTT 1219
             LHVVL K+A+ YG +MT+W    +P I+VSD D AWEV+V K+SDYS+R +P IT+  T
Sbjct: 57   ALHVVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGT 116

Query: 1218 ADWRTLATSNLGPYWQTLRKGLHSNVINPQTISSQTQLQEKDIADLISSFEQEASSNDGV 1039
            A+WRT+++S+ GP+W TLRKGL S  ++PQ ++SQT  QE+DI  LI + + EA+S  G+
Sbjct: 117  ANWRTISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAAS--GM 174

Query: 1038 VEPMPXXXXXXXXXIARFCFGPEFLTDEHFVERMDCAVEDEINLSGHTSLVDMFEFIRFI 859
            V+P+          I+R  +G +F  D+ +VE M   +E  I +SG+  L ++F + +++
Sbjct: 175  VKPLDHLKKATVRLISRLIYGQDF-DDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYL 233

Query: 858  PGFGRPFKEAENLKQRIMELISPYLSTHKPSSPNCYLSFLLSQGLSEEVVICNLFELFVL 679
            PG  R    AE  K+R++ L+ P+L ++   + N YL FL SQ   EEV+I  +FE ++L
Sbjct: 234  PGHKRAVTGAEEAKRRVIALVRPFLQSN--PATNTYLHFLKSQLYPEEVIIFAIFEAYLL 291

Query: 678  AIDSTSTAITWALAFMIHNGEIQERVLKEVMKKGLXXXXXXXXXXXXXEMEYVHALVKET 499
             +DSTS+   WALAF+I    +QE++ +E+                  ++ Y+ A+VKET
Sbjct: 292  GVDSTSSTTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKET 351

Query: 498  LRMRPVAPLG-PHGAARDSELKGMKVREGTPVWVNLYAMLHDERVWKEPNRFMPERFLVG 322
            +RM+P+APL  PH A +D+ L G KV +GT V VN++A+ H E+VWKEP +F+PERFL  
Sbjct: 352  MRMKPIAPLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFL-- 409

Query: 321  SGASGDRDDVWAMERSFVAFGAGRRNCGGMELAKIQVAVTVANLVNSFEWCSAVEGQLPD 142
                 D+    AME+S + F AG R C GMEL K+Q + ++ANLVN+F+W    +G LPD
Sbjct: 410  --QKHDK----AMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPD 463

Query: 141  LSQDLTPLLVMKTPLVARVVPR 76
            +S  L  +L MKTPL AR+VPR
Sbjct: 464  MSDLLGFVLFMKTPLEARIVPR 485


>gb|AGC29953.1| CYP719A23 [Sinopodophyllum hexandrum]
          Length = 489

 Score =  395 bits (1015), Expect = e-107
 Identities = 213/500 (42%), Positives = 322/500 (64%), Gaps = 1/500 (0%)
 Frame = -1

Query: 1572 EMEVSSLWITVATVFLLGLLMKLLDQTFFRTSSKQQWPPGPTKLPLIGNLHQLNRGGELL 1393
            EME+S L   +++  +L L M L+     ++SS  +WPPGP  LP+IGNLHQL  GG+ L
Sbjct: 2    EMEMSVL--AMSSTLILALAMALIFLFKAKSSSAIKWPPGPKTLPIIGNLHQL--GGDEL 57

Query: 1392 HVVLSKMAQKYGGIMTVWFSGQQPSIVVSDHDVAWEVMVTKASDYSSRVLPSITRFTTAD 1213
            H+VL+K+A+ +G IMT+W + ++P IVVSD +  WEV+V+K+SDY++R    I++  +A 
Sbjct: 58   HIVLAKLARVHGAIMTIWMA-KKPVIVVSDVNSVWEVLVSKSSDYAARDAAEISKIVSAS 116

Query: 1212 WRTLATSNLGPYWQTLRKGLHSNVINPQTISSQTQLQEKDIADLISSFEQEASSNDGVVE 1033
              ++ TS+ GPYWQTLR+GL    + P  IS+Q  +Q++D+  +I   +Q+A++N G+++
Sbjct: 117  SHSINTSDSGPYWQTLRRGLTHGPLGPLNISAQIPIQQRDMQRVIREMQQDAAANGGIIK 176

Query: 1032 PMPXXXXXXXXXIARFCFGPEFLTDEHFVERMDCAVEDEINLSGHTSLVDMFEFIRFIPG 853
            P+          ++R  FG  F  D  + + M   V+D     G   L   F F + +P 
Sbjct: 177  PLDHLKRSSTRLVSRLIFGDTFDNDP-YNDSMHEVVQDLNRFGGIALLEQAFSFAKHLPS 235

Query: 852  FGRPFKEAENLKQRIMELISPYLSTHKPSSPNCYLSFLLSQGLSEEVVICNLFELFVLAI 673
            + R  KE    K++I +L+ P +++  P S N YL FL SQ  SEE++I  +FEL++LA+
Sbjct: 236  YKRGVKEFHIHKRKIDDLVRPVVASANPPS-NSYLGFLQSQNYSEEIIIACIFELYLLAM 294

Query: 672  DSTSTAITWALAFMIHNGEIQERVLKEVMKKGLXXXXXXXXXXXXXEMEYVHALVKETLR 493
            DS+++  TWALAFMI + ++QE++ +++ K+ +             +M Y+ A+VKET+R
Sbjct: 295  DSSASTATWALAFMIRDQQVQEKLYQDI-KRVIGDGVDLVKAEDLSKMHYLQAVVKETMR 353

Query: 492  MRPVAPLG-PHGAARDSELKGMKVREGTPVWVNLYAMLHDERVWKEPNRFMPERFLVGSG 316
            M+P+APL  PH  A D+ + G KV +GT V VNLYA+ HDE VW +P  FMPERFL G  
Sbjct: 354  MKPIAPLAIPHKTAIDTTVMGTKVPKGTCVMVNLYALHHDESVWAKPYTFMPERFLQG-- 411

Query: 315  ASGDRDDVWAMERSFVAFGAGRRNCGGMELAKIQVAVTVANLVNSFEWCSAVEGQLPDLS 136
                 D     E++F+ FGAG R CGGME+ K+Q ++ +ANLVN+F+W SA EG+LPD+S
Sbjct: 412  ----EDGKSVTEQAFLPFGAGMRICGGMEVGKLQFSLALANLVNAFKWTSAAEGKLPDMS 467

Query: 135  QDLTPLLVMKTPLVARVVPR 76
             +L  + VMKTPL AR++PR
Sbjct: 468  DELQFITVMKTPLEARIIPR 487


>sp|B1NF20.1|C719E_ARGME RecName: Full=Cheilanthifoline synthase; Short=CHS; AltName:
            Full=Cytochrome P450 719A14 gi|148841094|gb|ABR14722.1|
            cheilanthifoline synthase [Argemone mexicana]
          Length = 494

 Score =  395 bits (1014), Expect = e-107
 Identities = 195/496 (39%), Positives = 319/496 (64%), Gaps = 2/496 (0%)
 Frame = -1

Query: 1557 SLWITVATVFL-LGLLMKLLDQTFFRTSSKQQWPPGPTKLPLIGNLHQLNRGGELLHVVL 1381
            ++W+ ++TV + LG+   LL ++   + S  +WP GP KLP+IGNLHQL  GG++ HVVL
Sbjct: 4    TIWLIISTVIIVLGIAKFLLGKSSSSSLSTMEWPVGPKKLPIIGNLHQL--GGDVFHVVL 61

Query: 1380 SKMAQKYGGIMTVWFSGQQPSIVVSDHDVAWEVMVTKASDYSSRVLPSITRFTTADWRTL 1201
            + +A+ YG + T+W    +P I+VSD D AWEV+V K+SDYS+R +P IT+  +A+W+ +
Sbjct: 62   ANLAKVYGSVFTIWVGSWRPMIIVSDIDKAWEVLVNKSSDYSARDMPDITKIISANWKNI 121

Query: 1200 ATSNLGPYWQTLRKGLHSNVINPQTISSQTQLQEKDIADLISSFEQEASSNDGVVEPMPX 1021
            + S+ GP+W  LRKGL    + P  ++SQ  LQE+D+ +LI+S  ++AS  +G+++P+  
Sbjct: 122  SCSDSGPFWHNLRKGLQGVALTPLNVASQYHLQERDMKNLINSMYKDASRKNGILKPLDY 181

Query: 1020 XXXXXXXXIARFCFGPEFLTDEHFVERMDCAVEDEINLSGHTSLVDMFEFIRFIPGFGRP 841
                    ++R  FG +F  DE  V  M  A++D + +SG+ SL D F+F   +P   + 
Sbjct: 182  LKEETVRLLSRLIFGQDF-QDEKLVVGMHHALDDLVRISGYASLADAFKFCENLPSHKKS 240

Query: 840  FKEAENLKQRIMELISPYLSTHKPSSPNCYLSFLLSQGLSEEVVICNLFELFVLAIDSTS 661
             +E   +K+R+  LI P++ ++ P+  N YL FL +Q  +E+++I  + E++ L +DST+
Sbjct: 241  IREVHEVKKRVENLIRPHIVSNPPT--NTYLYFLKTQDFNEDIIISAILEVYDLGVDSTA 298

Query: 660  TAITWALAFMIHNGEIQERVLKEVMKKGLXXXXXXXXXXXXXEMEYVHALVKETLRMRPV 481
            +   WAL F++   EIQE++ +E++   +             +M Y+ A++KET+RM+P+
Sbjct: 299  STTVWALTFLVREQEIQEKLYREIV--NVTGGKRSVKVEDVNKMPYLQAVMKETMRMKPI 356

Query: 480  APLG-PHGAARDSELKGMKVREGTPVWVNLYAMLHDERVWKEPNRFMPERFLVGSGASGD 304
            AP+  PH  ++D+ L G K+ +G+ + VNLYA+ H+ +V+ EP +FMPERFL    +   
Sbjct: 357  APMAIPHKTSKDTSLMGKKINKGSVIMVNLYAIHHNPKVFPEPYKFMPERFLKDVNSDES 416

Query: 303  RDDVWAMERSFVAFGAGRRNCGGMELAKIQVAVTVANLVNSFEWCSAVEGQLPDLSQDLT 124
              ++  ME S +AF AG R C GMEL K+Q+A  +A+LV+ F+W  +V+G+LPDLS+D  
Sbjct: 417  LGNIKTMESSLLAFSAGMRICAGMELGKLQLAFGLASLVHEFKWSCSVDGKLPDLSEDHC 476

Query: 123  PLLVMKTPLVARVVPR 76
             +L+MK PL A++  R
Sbjct: 477  FILLMKNPLEAKITCR 492


>sp|Q50LH4.1|C7193_ESCCA RecName: Full=(S)-stylopine synthase 2; Short=STS; AltName:
            Full=Cytochrome P450 719A3; Short=EcCYP719A3;
            Short=EcCYPA gi|63108254|dbj|BAD98249.1| stylopine
            synthase [Eschscholzia californica]
          Length = 495

 Score =  394 bits (1011), Expect = e-106
 Identities = 211/495 (42%), Positives = 307/495 (62%), Gaps = 3/495 (0%)
 Frame = -1

Query: 1551 WITVATVFLLGLLMKLLDQTFFRTSSKQQWPPGPTKLPLIGNLHQLNRGGELLHVVLSKM 1372
            W+  AT   L + + L    F R S    WP GP  LP+IGN+H L  GG  L VVL  +
Sbjct: 13   WVLFATSATLLISIFLF---FRRKSPNMAWPEGPKTLPIIGNMHLL--GGTALQVVLYNL 67

Query: 1371 AQKYGGIMTVWFSGQQPSIVVSDHDVAWEVMVTKASDYSSRVLPSITRFTTADWRTLATS 1192
            A+ +G +MT+W    +P IVVSD + AWEV+V K+SDYS+R +P IT+  TADWRT++TS
Sbjct: 68   AKVHGRVMTIWIGSWRPVIVVSDIEQAWEVLVNKSSDYSARDMPDITKIVTADWRTISTS 127

Query: 1191 NLGPYWQTLRKGLHSNVINPQTISSQTQLQEKDIADLISSFEQEASSNDGVVEPMPXXXX 1012
            + GP+W  LRKGL +  I+P  +++Q Q QEKDI  +I   EQEA  N+G+V+P+     
Sbjct: 128  DSGPHWSNLRKGLQNIAISPNNLAAQFQFQEKDIIKMIQILEQEAKDNNGIVKPLDHLKK 187

Query: 1011 XXXXXIARFCFGPEFLTDEHFVERMDCAVEDEINLSGHTSLVDMFEFIRFIPGFGRPFKE 832
                 I+R  FG +F  D+ +VE M  A+E+ I +SG+  L + F + +++P   +  + 
Sbjct: 188  ATIRLISRLVFGRDFEEDK-YVEDMHHAIEELIRISGYARLAEAFYYAKYLPSHRKAVRY 246

Query: 831  AENLKQRIMELISPYLSTHKPSSPNCYLSFLLSQGLSEEVVICNLFELFVLAIDSTSTAI 652
             E LKQ +  LI P+LS + P+  N YL FL SQ   EEVVI  +FE ++L +DSTS+  
Sbjct: 247  VEELKQIVKNLIRPFLSVNPPT--NTYLHFLRSQNYDEEVVIFAIFETYLLGVDSTSSTT 304

Query: 651  TWALAFMIHNGEIQERVLKEVMKKGLXXXXXXXXXXXXXEMEYVHALVKETLRMRPVAPL 472
             WALA+++    +Q+R+ +E+                  +++Y+ A++KET+RM+P+APL
Sbjct: 305  AWALAYLVREPSVQDRLHQELDHFAKQNDRKILKVEDMNKLQYLQAVIKETMRMKPIAPL 364

Query: 471  G-PHGAARDSELKGMKVREGTPVWVNLYAMLHDERVWKEPNRFMPERFLVGSGASGDRDD 295
              PH A +D+ L G K+ +GT V VNLYA+ H++ V+ +P +FMPERFL       D  D
Sbjct: 365  AIPHKACKDTSLMGNKINKGTRVMVNLYALHHNKNVFNDPFKFMPERFL-----KVDNQD 419

Query: 294  V--WAMERSFVAFGAGRRNCGGMELAKIQVAVTVANLVNSFEWCSAVEGQLPDLSQDLTP 121
                AME+S + F AG R C GMEL K+Q +  +ANL+ +F+W    +G LPD+S +L  
Sbjct: 420  AKGKAMEQSLLPFSAGMRICAGMELGKLQFSFALANLIFAFKWSCVDDGVLPDMSDELGF 479

Query: 120  LLVMKTPLVARVVPR 76
            +L+MKTPL AR+ PR
Sbjct: 480  VLLMKTPLKARINPR 494


>gb|ACO90219.1| stylopine synthase [Eschscholzia californica]
          Length = 495

 Score =  392 bits (1008), Expect = e-106
 Identities = 203/492 (41%), Positives = 309/492 (62%), Gaps = 3/492 (0%)
 Frame = -1

Query: 1551 WITVATVFLLGLLMKLLDQTFFRTSSKQQWPPGPTKLPLIGNLHQLNRGGELLHVVLSKM 1372
            WI  AT   L + + L    F R SSK  WP GP  LP+IGN+H L  GG  L VVL  +
Sbjct: 13   WILTATATTLLISIFLF---FTRKSSKMVWPAGPKTLPIIGNMHLL--GGTALQVVLHNL 67

Query: 1371 AQKYGGIMTVWFSGQQPSIVVSDHDVAWEVMVTKASDYSSRVLPSITRFTTADWRTLATS 1192
            A+ +G +MT+W    +P IVVSD + AWEV+V K+SDYS+R +P IT+  +ADW+T++TS
Sbjct: 68   AKVHGSVMTIWIGSWRPVIVVSDIERAWEVLVNKSSDYSARDMPDITKIISADWKTISTS 127

Query: 1191 NLGPYWQTLRKGLHSNVINPQTISSQTQLQEKDIADLISSFEQEASSNDGVVEPMPXXXX 1012
            + GP+W  LRKGL +  ++P  +++Q Q QEKD+  +I + ++EA +N+G+V+P+     
Sbjct: 128  DSGPHWTNLRKGLQNVALSPHNLAAQFQFQEKDMTKMIQTLQEEARNNNGIVKPLDHMKK 187

Query: 1011 XXXXXIARFCFGPEFLTDEHFVERMDCAVEDEINLSGHTSLVDMFEFIRFIPGFGRPFKE 832
                 I+R  FG +F  D+ +V+ M  A+E+ I +SG+  L + F + +++P   +  +E
Sbjct: 188  ATLRLISRLVFGQDFNNDK-YVDDMHLAIEELIRVSGYARLAEAFYYAKYLPSHKKAVRE 246

Query: 831  AENLKQRIMELISPYLSTHKPSSPNCYLSFLLSQGLSEEVVICNLFELFVLAIDSTSTAI 652
             E  ++R+  L+SP+LS + P+  N YL FL SQ   +EV+I  +FE ++L +DSTS   
Sbjct: 247  VEEAQRRVQNLVSPFLSLNPPT--NTYLHFLRSQKYDDEVIIFAIFEAYLLGVDSTSLTT 304

Query: 651  TWALAFMIHNGEIQERVLKEVMKKGLXXXXXXXXXXXXXEMEYVHALVKETLRMRPVAPL 472
             WALAF+I    +QE++ +E+                  +++Y+ A++KET+RM+P+APL
Sbjct: 305  AWALAFLIRESNVQEKLYQELESFASKMDRKILKVEDINKLQYLQAVIKETMRMKPIAPL 364

Query: 471  G-PHGAARDSELKGMKVREGTPVWVNLYAMLHDERVWKEPNRFMPERFLV--GSGASGDR 301
              PH A RD+ L G K+ +GT V VN+YA+ H++ V+ +P +FMPERF+      A+G  
Sbjct: 365  AIPHKACRDTSLMGKKIDKGTRVMVNIYALHHNKNVFNDPFKFMPERFMKVDSQDANGK- 423

Query: 300  DDVWAMERSFVAFGAGRRNCGGMELAKIQVAVTVANLVNSFEWCSAVEGQLPDLSQDLTP 121
                AME+S + F AG R C GMEL K+Q +  +ANL  +F+W    +G LPD+S  L  
Sbjct: 424  ----AMEQSLLPFSAGMRICAGMELGKLQFSFALANLAYAFKWSCVADGVLPDMSDQLGF 479

Query: 120  LLVMKTPLVARV 85
            +L+MKTPL AR+
Sbjct: 480  VLLMKTPLEARI 491


>sp|Q50LH3.1|C7192_ESCCA RecName: Full=(S)-stylopine synthase 1; Short=STS; AltName:
            Full=Cytochrome P450 719A2; Short=EcCYP719A2;
            Short=EcCYPB gi|63108256|dbj|BAD98250.1| stylopine
            synthase [Eschscholzia californica]
          Length = 495

 Score =  391 bits (1005), Expect = e-106
 Identities = 203/492 (41%), Positives = 309/492 (62%), Gaps = 3/492 (0%)
 Frame = -1

Query: 1551 WITVATVFLLGLLMKLLDQTFFRTSSKQQWPPGPTKLPLIGNLHQLNRGGELLHVVLSKM 1372
            WI  AT   L + + L    F R SSK  WP GP  LP+IGN+H L  GG  L VVL  +
Sbjct: 13   WILTATATTLLISIFLF---FTRKSSKMVWPAGPKTLPIIGNMHLL--GGTALQVVLHNL 67

Query: 1371 AQKYGGIMTVWFSGQQPSIVVSDHDVAWEVMVTKASDYSSRVLPSITRFTTADWRTLATS 1192
            A+ +G +MT+W    +P IVVSD + AWEV+V K+SDYS+R +P IT+  +ADW+T++TS
Sbjct: 68   AKVHGSVMTIWIGSWRPVIVVSDIERAWEVLVNKSSDYSARDMPDITKIISADWKTISTS 127

Query: 1191 NLGPYWQTLRKGLHSNVINPQTISSQTQLQEKDIADLISSFEQEASSNDGVVEPMPXXXX 1012
            + GP+W  LRKGL +  ++P  +++Q Q QEKD+  +I + E+EA +N+G+V+P+     
Sbjct: 128  DSGPHWTNLRKGLQNVALSPHNLAAQFQFQEKDMTKMIQTLEEEARNNNGIVKPLDHMKK 187

Query: 1011 XXXXXIARFCFGPEFLTDEHFVERMDCAVEDEINLSGHTSLVDMFEFIRFIPGFGRPFKE 832
                 I+R  FG +F  D+ +V+ M  A+E+ I +SG+  L + F + +++P   +  +E
Sbjct: 188  ATLRLISRLVFGQDFNNDK-YVDDMHLAIEELIRVSGYARLAEAFYYAKYLPSHKKAVRE 246

Query: 831  AENLKQRIMELISPYLSTHKPSSPNCYLSFLLSQGLSEEVVICNLFELFVLAIDSTSTAI 652
             E  ++R+  L+SP+LS + P+  N YL FL SQ   +EV+I  +FE ++L +DSTS   
Sbjct: 247  VEEAQRRVQNLVSPFLSLNPPT--NTYLHFLRSQKYDDEVIIFAIFEAYLLGVDSTSLTT 304

Query: 651  TWALAFMIHNGEIQERVLKEVMKKGLXXXXXXXXXXXXXEMEYVHALVKETLRMRPVAPL 472
             WALAF+I    +QE++ +E+                  +++Y+ A++KET+RM+P+APL
Sbjct: 305  AWALAFLIREPNVQEKLYQELESFASKNDRRILKVEDINKLQYLQAVIKETMRMKPIAPL 364

Query: 471  G-PHGAARDSELKGMKVREGTPVWVNLYAMLHDERVWKEPNRFMPERFLV--GSGASGDR 301
              PH A RD+ L G K+ +GT V VN++A+ H++ V+ +P +FMPERF+      A+G  
Sbjct: 365  AIPHKACRDTSLMGKKIDKGTRVMVNIFALHHNKNVFNDPFKFMPERFMKVDSQDANGK- 423

Query: 300  DDVWAMERSFVAFGAGRRNCGGMELAKIQVAVTVANLVNSFEWCSAVEGQLPDLSQDLTP 121
                AME+S + F AG R C GMEL K+Q +  +ANL  +F+W    +G LPD+S  L  
Sbjct: 424  ----AMEQSLLPFSAGMRICAGMELGKLQFSFALANLAYAFKWSCVADGVLPDMSDQLGF 479

Query: 120  LLVMKTPLVARV 85
            +L+MKTPL AR+
Sbjct: 480  VLLMKTPLEARI 491


>dbj|BAG75116.1| cytochrome P450 [Eschscholzia californica]
          Length = 495

 Score =  391 bits (1004), Expect = e-106
 Identities = 208/493 (42%), Positives = 306/493 (62%), Gaps = 1/493 (0%)
 Frame = -1

Query: 1551 WITVATVFLLGLLMKLLDQTFFRTSSKQQWPPGPTKLPLIGNLHQLNRGGELLHVVLSKM 1372
            WI  AT   L + M L    F R SSK  WP GP  LP+IGN+H L  GG  L VVL  +
Sbjct: 13   WILTATATTLLISMFLF---FTRKSSKMVWPQGPKTLPIIGNMHLL--GGTALQVVLHNL 67

Query: 1371 AQKYGGIMTVWFSGQQPSIVVSDHDVAWEVMVTKASDYSSRVLPSITRFTTADWRTLATS 1192
            A+ +G +MT+W    +P IVVSD + AWEV+V K+SDYS+R LP I ++ TAD RT+AT 
Sbjct: 68   AKVHGSVMTIWIGSWRPVIVVSDIERAWEVLVNKSSDYSARELPDIIKYNTADCRTIATC 127

Query: 1191 NLGPYWQTLRKGLHSNVINPQTISSQTQLQEKDIADLISSFEQEASSNDGVVEPMPXXXX 1012
            + GP+W  LRKGL +  ++P  +++Q Q QEKD+  +I   EQEA + +G+V+P+     
Sbjct: 128  DSGPHWSNLRKGLQNVALSPNNLAAQFQFQEKDVIKMIDILEQEAINKNGIVKPLDHLKK 187

Query: 1011 XXXXXIARFCFGPEFLTDEHFVERMDCAVEDEINLSGHTSLVDMFEFIRFIPGFGRPFKE 832
                 I+R  FG +F  D+ +VE +  A+E+ I +SG+  L + F + +++P   +  + 
Sbjct: 188  ATIRLISRLVFGQDF-NDDKYVEDLHQAIEELIRMSGYAQLAEAFYYAKYLPSHKKAIRH 246

Query: 831  AENLKQRIMELISPYLSTHKPSSPNCYLSFLLSQGLSEEVVICNLFELFVLAIDSTSTAI 652
            AE  KQ +  L+ P+LS + P+  N YL FL SQ   EE+VI  +FE ++L +DSTS+  
Sbjct: 247  AELTKQIVTNLVRPFLSLNPPT--NSYLHFLQSQKYDEEMVIFAIFETYLLGVDSTSSTT 304

Query: 651  TWALAFMIHNGEIQERVLKEVMKKGLXXXXXXXXXXXXXEMEYVHALVKETLRMRPVAPL 472
             WALA+++    +Q+R+  E+                  +++Y+ A+ KET+RM+P+APL
Sbjct: 305  AWALAYLVREPNVQDRLYNELNNYANYNDRKILKVEVINKLQYLQAVTKETMRMKPIAPL 364

Query: 471  G-PHGAARDSELKGMKVREGTPVWVNLYAMLHDERVWKEPNRFMPERFLVGSGASGDRDD 295
              PH A RD+ L G K+ +GT V VNL+A+ H+E V+ +P +FMPERFL     + +  +
Sbjct: 365  AIPHKACRDTSLMGTKIDKGTKVMVNLHALHHNENVFTDPFKFMPERFL---KVNNEDVN 421

Query: 294  VWAMERSFVAFGAGRRNCGGMELAKIQVAVTVANLVNSFEWCSAVEGQLPDLSQDLTPLL 115
            + AME+S + F AG R C GMEL K+Q +  +ANLV +F+W    +G LPD+S +L  +L
Sbjct: 422  MKAMEQSLLPFSAGMRICAGMELGKLQFSFALANLVYAFKWSCVDDGVLPDMSDELGFVL 481

Query: 114  VMKTPLVARVVPR 76
             MKTPL AR+V R
Sbjct: 482  FMKTPLEARIVRR 494


>gb|ADB89213.1| cheilanthifoline synthase [Papaver somniferum]
          Length = 492

 Score =  390 bits (1003), Expect = e-105
 Identities = 204/501 (40%), Positives = 314/501 (62%), Gaps = 3/501 (0%)
 Frame = -1

Query: 1569 MEVSSLWITVATVFLLGLLMKLLDQTFFRTSSKQ--QWPPGPTKLPLIGNLHQLNRGGEL 1396
            MEV+  W+    V +   L KLL   F + SS    +WP GP  LP+IGNLHQL  GGE 
Sbjct: 1    MEVT-FWLITCGVVVAFALAKLL---FGKKSSMSTMEWPSGPKTLPIIGNLHQL--GGEA 54

Query: 1395 LHVVLSKMAQKYGGIMTVWFSGQQPSIVVSDHDVAWEVMVTKASDYSSRVLPSITRFTTA 1216
             HV L+ +A+ YGG+ T+W    +P IV+SD D AWEV+V K+SDYS+R +P IT+  +A
Sbjct: 55   FHVCLANLAKVYGGVFTIWVGSWRPFIVISDVDKAWEVLVNKSSDYSARDMPDITKIISA 114

Query: 1215 DWRTLATSNLGPYWQTLRKGLHSNVINPQTISSQTQLQEKDIADLISSFEQEASSNDGVV 1036
            +W+ ++  + GP+W  LRKGL    + P  ++SQ  LQE+D+ +LI S +++AS  +G++
Sbjct: 115  NWKNISHGDSGPFWHNLRKGLQGVALTPFNVASQYHLQERDMQNLIKSMKKKASQKNGIL 174

Query: 1035 EPMPXXXXXXXXXIARFCFGPEFLTDEHFVERMDCAVEDEINLSGHTSLVDMFEFIRFIP 856
            +P+          ++R  FG +F+ DE FV  M  A+++ +++SG+ SL D F+F   +P
Sbjct: 175  KPLDYVKEETVRLLSRLIFGQDFV-DEDFVVGMHQALDELVSISGYASLADAFKFCENLP 233

Query: 855  GFGRPFKEAENLKQRIMELISPYLSTHKPSSPNCYLSFLLSQGLSEEVVICNLFELFVLA 676
               +  +    +K R   LI P++ ++ P+  N YL FLLSQ  SE+V+I  + E++ L 
Sbjct: 234  SHKKTVRAVHAIKIRFDNLIRPHIVSNPPT--NTYLHFLLSQDFSEDVIISAILEVYDLG 291

Query: 675  IDSTSTAITWALAFMIHNGEIQERVLKEVMKKGLXXXXXXXXXXXXXEMEYVHALVKETL 496
            +DST++   WAL F++   +IQE++ +E+    +             ++ Y+ A++KET+
Sbjct: 292  VDSTASTTVWALTFLVREQKIQEKLYREI--NNVTGGKKPVKVEDLNKLPYLQAVMKETM 349

Query: 495  RMRPVAPLG-PHGAARDSELKGMKVREGTPVWVNLYAMLHDERVWKEPNRFMPERFLVGS 319
            RM+P+AP+  PH A++D+ L G K+ +G  V VNLYA+ H+  V+ EP +FMPERFL  +
Sbjct: 350  RMKPIAPMAIPHKASKDTSLMGKKINKGAVVMVNLYAIHHNPAVFPEPYKFMPERFLKDA 409

Query: 318  GASGDRDDVWAMERSFVAFGAGRRNCGGMELAKIQVAVTVANLVNSFEWCSAVEGQLPDL 139
             + G   D+  ME S +AF AG R C GMEL K+Q+A  +A+LVN F+W    EG+LPDL
Sbjct: 410  NSDGSLGDIKKMESSLLAFSAGMRICAGMELGKLQLAFGLASLVNEFKWDCFAEGKLPDL 469

Query: 138  SQDLTPLLVMKTPLVARVVPR 76
            S++   +L+MK PL A++ PR
Sbjct: 470  SEEHCFILLMKNPLEAKITPR 490


>gb|AGC29954.1| CYP719A24 [Podophyllum peltatum]
          Length = 489

 Score =  389 bits (999), Expect = e-105
 Identities = 212/501 (42%), Positives = 321/501 (64%), Gaps = 2/501 (0%)
 Frame = -1

Query: 1572 EMEVSSLWITVATVFLLGLLMKLLDQTFFRTSSKQQWPPGPTKLPLIGNLHQLNRGGELL 1393
            EME S L ++   +  L + +  L +   ++SS  +WPPGP  LP+IGNLHQL  GG+ L
Sbjct: 2    EMETSVLGLSSTLIIALAITVIFLLKA--KSSSAIKWPPGPKTLPIIGNLHQL--GGDEL 57

Query: 1392 HVVLSKMAQKYGGIMTVWFSGQQPSIVVSDHDVAWEVMVTKASDYSSRVLPSITRFTTAD 1213
            H+VL+K+A+ +G IMT+W + ++P IVVSD +  WEV+V+K+SDY++R    I++  +A 
Sbjct: 58   HIVLAKLARVHGAIMTIWMA-KKPVIVVSDVNSVWEVLVSKSSDYAARDAAEISKIVSAS 116

Query: 1212 WRTLATSNLGPYWQTLRKGLHSNVINPQTISSQTQLQEKDIADLISSFEQEASSNDGVVE 1033
              ++ TS+ GPYWQTLR+GL    + P  IS+Q  +Q++D+  +I   +Q+A++N GV++
Sbjct: 117  SHSINTSDSGPYWQTLRRGLTHGPLGPLNISAQIPIQQRDMQRVIREMQQDAAANGGVIK 176

Query: 1032 PMPXXXXXXXXXIARFCFGPEFLTDEHFVERMDCAVEDEINLSGHTSLVDMFEFIRFIPG 853
            P+          ++R  FG  F  D  + + M   V+D     G   L   F F +++P 
Sbjct: 177  PLDHLKRSSTRLVSRLIFGDTFDNDP-YNDSMHEVVQDLNRFGGIALLEQAFSFAKYLPS 235

Query: 852  FGRPFKEAENLKQRIMELISPYLSTHKPSSPNCYLSFLLSQGLSEEVVICNLFELFVLAI 673
            + R  KE    K++I +L+ P +++  P S N YL FL SQ  SEE++I  +FEL++L  
Sbjct: 236  YKRGVKEFHIHKRKIDDLVRPVVASSNPPS-NSYLGFLQSQNYSEEIIIACIFELYLLXX 294

Query: 672  DSTSTAITWALAFMIHNGEIQERVLKEVMKKGLXXXXXXXXXXXXXEMEYVHALVKETLR 493
            DS+++  TWALAF I + ++QE++ +++ K+ +             +M Y+ A+VKET+R
Sbjct: 295  DSSASTATWALAFXIRDQQVQEKLYQDI-KRVIGDEVGLVKAEDLSKMHYLQAVVKETMR 353

Query: 492  MRPVAPLG-PHGAARDSELKGMKVREGTPVWVNLYAMLHDERVWKEPNRFMPERFLVGSG 316
            M+P+APL  PH  A D+ L G KV +GT V VNLYA+ HDE VW +P  FMPERFL    
Sbjct: 354  MKPIAPLAIPHKTAIDTSLMGTKVPKGTCVMVNLYALHHDESVWAKPYTFMPERFL---- 409

Query: 315  ASGDRDDVWAM-ERSFVAFGAGRRNCGGMELAKIQVAVTVANLVNSFEWCSAVEGQLPDL 139
                R+D  ++ E++F+ FGAG R CGGME+ K+Q ++ +ANLVN+F+W SA EG+LPD+
Sbjct: 410  ---QREDGKSVTEQAFLPFGAGMRICGGMEVGKLQFSLALANLVNAFKWTSAAEGKLPDM 466

Query: 138  SQDLTPLLVMKTPLVARVVPR 76
            S +L  + VMKTPL AR+VPR
Sbjct: 467  SDELQFITVMKTPLEARIVPR 487


>dbj|BAG75115.1| cytochrome P450 [Eschscholzia californica]
          Length = 494

 Score =  389 bits (998), Expect = e-105
 Identities = 202/493 (40%), Positives = 303/493 (61%), Gaps = 1/493 (0%)
 Frame = -1

Query: 1551 WITVATVFLLGLLMKLLDQTFFRTSSKQQWPPGPTKLPLIGNLHQLNRGGELLHVVLSKM 1372
            W+  AT   L + M L    F R SSK  WP GP  LP+IGN+H L  G + L V+L  +
Sbjct: 13   WVVTATSATLLISMFLF---FTRKSSKMVWPKGPKTLPIIGNMHLLG-GSKALQVILHNL 68

Query: 1371 AQKYGGIMTVWFSGQQPSIVVSDHDVAWEVMVTKASDYSSRVLPSITRFTTADWRTLATS 1192
            ++ +G +MT+W    +P IVVS+ +  WEV+V K+SDYS R +P + +F +AD+RT++TS
Sbjct: 69   SKVHGSVMTIWIGRWRPVIVVSNIERVWEVLVNKSSDYSGRYVPDVIKFVSADFRTISTS 128

Query: 1191 NLGPYWQTLRKGLHSNVINPQTISSQTQLQEKDIADLISSFEQEASSNDGVVEPMPXXXX 1012
            + GP+W  LRKGL +  ++P ++++Q Q QEKDI  +    E+EA +N G+V+P+     
Sbjct: 129  DSGPHWTNLRKGLQNVALSPNSLAAQFQFQEKDIIKMTDILEREARNNKGIVKPLDHLKK 188

Query: 1011 XXXXXIARFCFGPEFLTDEHFVERMDCAVEDEINLSGHTSLVDMFEFIRFIPGFGRPFKE 832
                 I+R  FGP F  D+ +VE M   +++ I +S +  L + F + +++P   +  + 
Sbjct: 189  ATVRLISRLVFGPNF-NDDQYVEDMHNTIDELIQMSSYAQLAEAFYYAKYLPSHRKAVRH 247

Query: 831  AENLKQRIMELISPYLSTHKPSSPNCYLSFLLSQGLSEEVVICNLFELFVLAIDSTSTAI 652
             E  KQ + +LI PY+S   P  PN YL FL SQ   EEVVI  +FE ++L +DSTS+  
Sbjct: 248  FEQTKQIVKKLIRPYISVSPP--PNTYLHFLQSQNYDEEVVIFAIFEAYLLGVDSTSSTT 305

Query: 651  TWALAFMIHNGEIQERVLKEVMKKGLXXXXXXXXXXXXXEMEYVHALVKETLRMRPVAPL 472
            TWALAF+I    +QE++ +E+                  +++Y+ A+ KET+RM+PVAPL
Sbjct: 306  TWALAFLIREPNVQEKLYQELKNFAEQNDREIMKVEDINKLQYLQAVTKETMRMKPVAPL 365

Query: 471  G-PHGAARDSELKGMKVREGTPVWVNLYAMLHDERVWKEPNRFMPERFLVGSGASGDRDD 295
              PH A R++ L GM + +GT V VN++++ H+E V+ +P  FMPERFL       D  +
Sbjct: 366  AIPHKACRETSLMGMPIDKGTKVMVNIHSLHHNENVFSDPFTFMPERFL-----KVDNQN 420

Query: 294  VWAMERSFVAFGAGRRNCGGMELAKIQVAVTVANLVNSFEWCSAVEGQLPDLSQDLTPLL 115
            V AME+S++ F AG R C G+EL K+     +ANLV +F+W    +G LPD+S++L  +L
Sbjct: 421  VKAMEQSYLPFSAGMRICAGIELGKLHFGFALANLVYAFKWSCVADGVLPDMSEELGTIL 480

Query: 114  VMKTPLVARVVPR 76
             MKTPL AR+V R
Sbjct: 481  FMKTPLEARIVRR 493


>dbj|BAF98471.1| cytochrome P450 [Coptis japonica var. dissecta]
          Length = 508

 Score =  387 bits (994), Expect = e-104
 Identities = 215/506 (42%), Positives = 318/506 (62%), Gaps = 7/506 (1%)
 Frame = -1

Query: 1572 EMEVSSLWITVATVFLLGLLMKLLDQTFFRTSSKQQ--WPPGPTKLPLIGNLHQLNRGGE 1399
            EME  SL +  AT+ +L  +  ++  T   +SS  Q  WP GP KLP+IGNLHQL   GE
Sbjct: 12   EME-GSLLLAGATLAILLTISTIVRITSSPSSSFSQMTWPSGPKKLPIIGNLHQLR--GE 68

Query: 1398 LLHVVLSKMAQKYGGIMTVWFSGQQPSIVVSDHDVAWEVMVTKASDYSSR---VLPSITR 1228
            LLHV L+K+A+ +GG+MT+W     P IV+SD + AWEV+V K++DY +R    L  + R
Sbjct: 69   LLHVTLAKLAKVHGGVMTIWMGSWVPIIVISDINSAWEVLVNKSADYGAREVTYLHELLR 128

Query: 1227 FTTADWRTLATSNLGPYWQTLRKGLHSNVINPQTISSQTQLQEKDIADLISSFEQEASSN 1048
             +      +++S++GP W  +RKGL S  ++P +++SQTQ +E+D+  ++    +E  +N
Sbjct: 129  DSAMHPHNISSSDVGPLWHNIRKGLQSGALSPLSVASQTQHRERDMKRVVHEMSREIVNN 188

Query: 1047 DGVVEPMPXXXXXXXXXIARFCFGPEFLTDEHFVERMDCAVEDEINLSGHTSLVDMFEFI 868
            +G ++P+          + R  FGP F  D  F+E M   +ED I  S +TSL + F + 
Sbjct: 189  NGTIKPLVHIKNSTARLLGRLIFGPSF-NDSKFIESMLYEIEDFIRTSSYTSLTNSFYYA 247

Query: 867  RFIPGFGRPFKEAENLKQRIMELISPYLSTHKPSSPNCYLSFLLSQGLSEEVVICNLFEL 688
            +++P   +  +EA+  K RI EL+ P LS+  P+  N YL FLLSQ LSEEV I  +FEL
Sbjct: 248  KYLPSQRKATREAKLGKYRIEELVRPLLSSKPPT--NAYLYFLLSQNLSEEVTIFCIFEL 305

Query: 687  FVLAIDSTSTAITWALAFMIHNGEIQERVLKEVMKKGLXXXXXXXXXXXXXEMEYVHALV 508
            F+L +DS S+  TWALA+MI   E QE++ +++  +               +++Y+ ++V
Sbjct: 306  FLLGVDSASSTTTWALAYMIREQEAQEKLYQDI--RMTIGDVDLVKIEDVNKLKYLQSVV 363

Query: 507  KETLRMRPVAPLG-PHGAARDSELKGMKVREGTPVWVNLYAMLHDERVWKEPNRFMPERF 331
            KET+RM+P+APL  PH A +D+ L G K+ +GT V VNLYA+ H E VW EP++FMPER+
Sbjct: 364  KETMRMKPIAPLALPHNAGKDTTLMGTKIVKGTRVMVNLYALHHYEDVWLEPSKFMPERY 423

Query: 330  LVGSGASGDRDDVWAMERSFVAFGAGRRNCGGMELAKIQVAVTVANLVNSFEWCSAVEGQ 151
            L G   S       AME+S + FGAG R C GM+L K+QVA  +ANLVN+F+W    +G+
Sbjct: 424  LQGEDGSVTHK---AMEQSLLPFGAGMRICAGMDLGKLQVAFVLANLVNAFKWSCVEDGK 480

Query: 150  LPDLSQDLTPLLV-MKTPLVARVVPR 76
            LPD++++L  L++ MKTPL  R+ PR
Sbjct: 481  LPDMTEELFGLIILMKTPLEGRISPR 506