BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Cocculus22_contig00004423
         (1228 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q8H9A8.1|COOMT_COPJA RecName: Full=Columbamine O-methyltransf...   353   6e-95
dbj|BAM37634.1| O-methyltransferase [Eschscholzia californica]        247   8e-63
gb|AAP45315.1| S-adenosyl-L-methionine:norcoclaurine 6-O-methylt...   233   2e-58
sp|Q6WUC1.1|6OMT_PAPSO RecName: Full=(RS)-norcoclaurine 6-O-meth...   231   5e-58
ref|XP_006364318.1| PREDICTED: trans-resveratrol di-O-methyltran...   230   8e-58
gb|AAP45313.1| S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclau...   230   8e-58
gb|AAU20765.1| (S)-norcoclaurine 6-O-methyltransferase [Thalictr...   229   2e-57
emb|CAN75970.1| hypothetical protein VITISV_009881 [Vitis vinifera]   229   2e-57
ref|XP_002278127.1| PREDICTED: isoflavone-7-O-methyltransferase ...   228   3e-57
sp|Q9LEL6.1|6OMT_COPJA RecName: Full=(RS)-norcoclaurine 6-O-meth...   228   4e-57
gb|ACO90232.1| putative norcoclaurine 6-O-methyltransferase [Pap...   228   4e-57
ref|XP_004232928.1| PREDICTED: trans-resveratrol di-O-methyltran...   228   5e-57
ref|XP_006364329.1| PREDICTED: uncharacterized protein LOC102587...   227   9e-57
ref|XP_006858228.1| hypothetical protein AMTR_s00062p00190100 [A...   227   9e-57
ref|XP_006364328.1| PREDICTED: trans-resveratrol di-O-methyltran...   226   1e-56
gb|ACO90250.1| norcoclaurine 6-O-methyltransferase-like protein ...   225   3e-56
gb|ACO90225.1| putative norcoclaurine 6-O-methyltransferase [Pap...   225   3e-56
gb|ABY75613.1| S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclau...   225   3e-56
gb|AAR09603.1| O-methyltransferase [Mentha x piperita]                224   4e-56
gb|AAU20768.1| 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltra...   224   6e-56

>sp|Q8H9A8.1|COOMT_COPJA RecName: Full=Columbamine O-methyltransferase; Short=CoOMT; AltName:
            Full=Tetrahydrocolumbamine 2-O-methyltransferase
            gi|24210466|dbj|BAC22084.1| columbamine
            O-methyltransferase [Coptis japonica]
          Length = 351

 Score =  353 bits (907), Expect = 6e-95
 Identities = 186/350 (53%), Positives = 244/350 (69%), Gaps = 1/350 (0%)
 Frame = -1

Query: 1138 TEEQEEEMKAKVQLGKHMYAFAETITLRCAVQLGIPDQIHKHGPLTLSELASKLQIESIN 959
            T + ++E+KA+ Q+ KHM+ FAETI LR  V LGIPD IH +GP+TLS+L + L ++S +
Sbjct: 6    TFQNDDEIKAQAQVWKHMFGFAETIMLRSTVSLGIPDIIHNNGPVTLSQLVTHLPLKSTS 65

Query: 958  MDRFELTMRYMVHMNLLTAIADEANGETKYGLTPASKLLLKSSHNNNKSLASFVMVQTDP 779
            +DRF   MRY+VHM L T   D+   E KY LTPASKLL+   H + KSLA +VM+QT P
Sbjct: 66   IDRFHHFMRYLVHMQLFTISTDQITKEDKYELTPASKLLV---HGHQKSLAPYVMLQTHP 122

Query: 778  EELFVSRHLVESLGGAKSCWELFYGVPVNEKLEKDEKWSR-MSDGMNGYTLCMVEAIVDG 602
            EE  V  H++  L G K  WE      + EK E D + +  ++D M  ++  M+ A+V G
Sbjct: 123  EEFSVWSHVINVLDGKKPYWES-NDTSMYEKTEGDPEINEILNDAMTSHSTFMLPALVSG 181

Query: 601  LKREKVIDQSVTSLVDVGGNTGVVAKAILSAFPHLKCTVMDFPHVVECVPKDPPLDFVGG 422
            L +E V+D  V S+VDVGGN+GVVAK I+ AFPH+KC+VMD  HV+E V K+P LD+V G
Sbjct: 182  LMKENVLD-GVASIVDVGGNSGVVAKGIVDAFPHVKCSVMDLNHVIERVIKNPKLDYVAG 240

Query: 421  DMFDTIPSADIVFFKSMFHGFEDDMCIKILNKCKEAMSPAKGKVILVEMVVDIETMLEFS 242
            DMF +IP+AD +  KS  H +EDD CIKILN  KEA+    GKVILVE+VVD E +  F+
Sbjct: 241  DMFTSIPNADAILLKSTLHNYEDDDCIKILNIAKEALPSTGGKVILVEIVVDTENLPLFT 300

Query: 241  SARLGLAMQMMFLGGKERTKKEWESLIYKAGFSDYKIIPIVAAESIIVAY 92
            SARL + M MM + GKERTKKEWE L+ KA F+ +++IPI+A ESIIVAY
Sbjct: 301  SARLSMGMDMMLMSGKERTKKEWEDLLRKANFTSHQVIPIMAIESIIVAY 350


>dbj|BAM37634.1| O-methyltransferase [Eschscholzia californica]
          Length = 351

 Score =  247 bits (630), Expect = 8e-63
 Identities = 138/347 (39%), Positives = 207/347 (59%), Gaps = 3/347 (0%)
 Frame = -1

Query: 1120 EMKAKVQLGKHMYAFAETITLRCAVQLGIPDQIHKHG-PLTLSELASKLQIESINMDRFE 944
            +   + ++ KH+Y FAE++ L+ AV+L I D IH HG P+TLSELASKL ++ +++DR  
Sbjct: 10   DQATQAKIWKHIYGFAESLILKSAVELEIADTIHNHGKPMTLSELASKLPVQPVDLDRLY 69

Query: 943  LTMRYMVHMNLLTAIADEANGETKYGLTPASKLLLKSSHNNNKSLASFVMVQTDPEELFV 764
              MRY+VHM L     DE     KY L P +K L+K      KS+ S +++  D + +  
Sbjct: 70   RVMRYLVHMKLFKKQEDEDEESIKYSLLPPAKFLIKGWE---KSMVSAILLINDKDFMSP 126

Query: 763  SRHLVESLGGAKSCWELFYGVPVNEKLEKD-EKWSRMSDGMNGYTLCMVEAIVDGLKREK 587
              HL E L    + ++   G  + + +  + +K    ++GM   +  +  A+V+      
Sbjct: 127  WHHLKEGLVNNSNAFDKALGKSIWDYMSANPDKNKVFNEGMACDSRLVSSALVNECGN-- 184

Query: 586  VIDQSVTSLVDVGGNTGVVAKAILSAFPHLKCTVMDFPHVVECVPKDPPLDFVGGDMFDT 407
             I Q + +LVDVGG TG   KA+  AFPH+KC++ D PHV+   P  P +  + G+MF +
Sbjct: 185  -IFQGIQTLVDVGGGTGTAVKAVSKAFPHIKCSIYDLPHVISDSPDIPNIVKIEGEMFKS 243

Query: 406  IPSADIVFFKSMFHGFEDDMCIKILNKCKEAMSPAKGKVILVEMVVDIETMLEFSSARLG 227
            IPSAD +  K + H + DD CI+IL KCKEA+    GKVI+V++V+D+E+   +S  RL 
Sbjct: 244  IPSADAILMKCILHDWNDDECIEILKKCKEAVPKEGGKVIIVDIVLDMESKHPYSKVRLT 303

Query: 226  LAMQMMF-LGGKERTKKEWESLIYKAGFSDYKIIPIVAAESIIVAYP 89
            L + MM    GKERT++EW+ LI  AGF+ YKI  I A +S+I A+P
Sbjct: 304  LDLDMMLNTEGKERTEEEWKKLIDGAGFASYKITQISALQSVIEAFP 350


>gb|AAP45315.1| S-adenosyl-L-methionine:norcoclaurine 6-O-methyltransferase [Papaver
            somniferum]
          Length = 346

 Score =  233 bits (593), Expect = 2e-58
 Identities = 137/353 (38%), Positives = 204/353 (57%), Gaps = 9/353 (2%)
 Frame = -1

Query: 1120 EMKAKVQLGKHMYAFAETITLRCAVQLGIPDQIHKH-GPLTLSELASKLQI-ESINMDRF 947
            + + + ++ K +Y FAE++ L+CAVQL I + +H +  P++LSELASKL + + +N DR 
Sbjct: 8    DQQNQAKIWKQIYGFAESLVLKCAVQLEIAETLHNNVKPMSLSELASKLPVAQPVNEDRL 67

Query: 946  ELTMRYMVHMNLLTAIADEANGETKYGLTPASKLLLKSSHNNNKSLASFVMVQTDPEELF 767
               MRY+VHM L    A       KY L P +K LL+      KS+   ++   D + L 
Sbjct: 68   FRIMRYLVHMELFKIDATTQ----KYSLAPPAKYLLRGWE---KSMVDSILCINDKDFLA 120

Query: 766  VSRHLVESLGGAKSCWELFYG----VPVNEKLEKDEKWSRMSDGMNGYTLCMVEAIVDGL 599
               HL + L G    +E   G    V ++E  EK++ +       N    C    +   L
Sbjct: 121  PWHHLGDGLTGNCDAFEKALGKSIWVYMSENPEKNQLF-------NAAMACDTRLVTSAL 173

Query: 598  KRE--KVIDQSVTSLVDVGGNTGVVAKAILSAFPHLKCTVMDFPHVVECVPKDPPLDFVG 425
              E   +    +++LVDVGG TG   KAI  AFP +KCT+ D PHV+   P+ P +  + 
Sbjct: 174  ANECKSIFSDGISTLVDVGGGTGTAVKAISKAFPDIKCTIYDLPHVIADSPEIPNITKIS 233

Query: 424  GDMFDTIPSADIVFFKSMFHGFEDDMCIKILNKCKEAMSPAKGKVILVEMVVDIETMLEF 245
            GDMF +IPSAD +F K + H + DD CI+IL +CKEA+ P  GKVI+V++V+D+++   +
Sbjct: 234  GDMFKSIPSADAIFMKCILHDWNDDECIQILKRCKEAL-PKVGKVIIVDVVIDMDSTHPY 292

Query: 244  SSARLGLAMQMMF-LGGKERTKKEWESLIYKAGFSDYKIIPIVAAESIIVAYP 89
            +  RL L + MM   GGKERTK+EW++L   AGF+ +K+  I A +S+I AYP
Sbjct: 293  AKIRLTLDLDMMLNTGGKERTKEEWKTLFDAAGFASHKVTQISAVQSVIEAYP 345


>sp|Q6WUC1.1|6OMT_PAPSO RecName: Full=(RS)-norcoclaurine 6-O-methyltransferase; Short=6OMT
            gi|33286374|gb|AAQ01669.1| (R,S)-norcoclaurine
            6-O-methyltransferase [Papaver somniferum]
            gi|571330878|gb|AHF27395.1| (R,S)-norcoclaurine
            6-O-methyltransferase [synthetic construct]
          Length = 346

 Score =  231 bits (589), Expect = 5e-58
 Identities = 133/349 (38%), Positives = 202/349 (57%), Gaps = 5/349 (1%)
 Frame = -1

Query: 1120 EMKAKVQLGKHMYAFAETITLRCAVQLGIPDQIHKH-GPLTLSELASKLQI-ESINMDRF 947
            + + + ++ K +Y FAE++ L+CAVQL I + +H +  P++LSELASKL + + +N DR 
Sbjct: 8    DQQNQAKIWKQIYGFAESLVLKCAVQLEIAETLHNNVKPMSLSELASKLPVAQPVNEDRL 67

Query: 946  ELTMRYMVHMNLLTAIADEANGETKYGLTPASKLLLKSSHNNNKSLASFVMVQTDPEELF 767
               MRY+VHM L    A       KY L P +K LL+      KS+   ++   D + L 
Sbjct: 68   FRIMRYLVHMELFKIDATTQ----KYSLAPPAKYLLRGWE---KSMVDSILCINDKDFLA 120

Query: 766  VSRHLVESLGGAKSCWELFYGVPVNEKLEKDEKWSRMSDGMNGYTLCMVEAIVDGLKRE- 590
               HL + L G    +E   G  +   +  + + +++    N    C    +   L  E 
Sbjct: 121  PWHHLGDGLTGNCDAFEKALGKSIWVYMSVNPEKNQL---FNAAMACDTRLVTSALANEC 177

Query: 589  -KVIDQSVTSLVDVGGNTGVVAKAILSAFPHLKCTVMDFPHVVECVPKDPPLDFVGGDMF 413
              +    +++LVDVGG TG   KAI  AFP +KCT+ D PHV+   P+ P +  + GDMF
Sbjct: 178  KSIFSDGISTLVDVGGGTGTAVKAISKAFPDIKCTIYDLPHVIADSPEIPNITKISGDMF 237

Query: 412  DTIPSADIVFFKSMFHGFEDDMCIKILNKCKEAMSPAKGKVILVEMVVDIETMLEFSSAR 233
             +IPSAD +F K + H + DD CI+IL +CKEA+ P  GKVI+V++V+D+++   ++  R
Sbjct: 238  KSIPSADAIFMKCILHDWNDDECIQILKRCKEAL-PKGGKVIIVDVVIDMDSTHPYAKIR 296

Query: 232  LGLAMQMMF-LGGKERTKKEWESLIYKAGFSDYKIIPIVAAESIIVAYP 89
            L L + MM   GGKERTK+EW++L   AGF+ +K+  I A +S+I AYP
Sbjct: 297  LTLDLDMMLNTGGKERTKEEWKTLFDAAGFASHKVTQISAVQSVIEAYP 345


>ref|XP_006364318.1| PREDICTED: trans-resveratrol di-O-methyltransferase-like [Solanum
            tuberosum]
          Length = 357

 Score =  230 bits (587), Expect = 8e-58
 Identities = 135/359 (37%), Positives = 209/359 (58%), Gaps = 14/359 (3%)
 Frame = -1

Query: 1123 EEMKAKVQLGKHMYAFAETITLRCAVQLGIPDQIHKHG-PLTLSELASKLQIESINMDRF 947
            E  + +  + KH ++FA ++ L CA+QLGIPD IH H  P+TLS+L S+L++     D  
Sbjct: 8    EMFQGQAHIYKHAFSFANSMVLGCAIQLGIPDVIHSHKQPMTLSQLVSELKLLPEKSDAI 67

Query: 946  ELTMRYMVHMNLLTA---IADEANGETKYGLTPASKLLLKSSHNNNKSLASFVMVQTDPE 776
               MR +V+         + + +  +  Y LTP+SKLLL+S   N   L+ F     DP 
Sbjct: 68   HRLMRLLVYSGFFATREFLDENSENQQGYVLTPSSKLLLRSEIPN---LSPFARAMVDPV 124

Query: 775  ELFVSRHLVE-SLGGAKSCWELFYGVPVNEKLEKDEKWSRMSD---GMNGYTLCMVEAIV 608
             +   + L +  LG   + +E  +G P+ +  +++ +++ + +     +   +C+V    
Sbjct: 125  MVNPWQSLGDWILGNETTPFETAHGAPMWQFCDQNPRFNNVFNEAMASDSQMMCLV---- 180

Query: 607  DGLKREKVIDQSVTSLVDVGGNTGVVAKAILSAFPHLKCTVMDFPHVVECVPKDPPLDFV 428
              +K  K + Q + SLVDVGG TG++A  IL+AFPHLKCTV+D PHVV  +P    L +V
Sbjct: 181  --VKDCKQVFQDMDSLVDVGGGTGIIANTILAAFPHLKCTVLDLPHVVANMPDTENLKYV 238

Query: 427  GGDMFDTIPSADIVFFKSMFHGFEDDMCIKILNKCKEAMSP----AKGKVILVEMVVD-I 263
            GGDMF +IPSAD + FK + H + D+ C+KIL +C+EA+       KGKV++++MV+D  
Sbjct: 239  GGDMFHSIPSADAILFKHVMHNWSDENCVKILKRCREAIKDKNEGRKGKVLIIDMVLDRD 298

Query: 262  ETMLEFSSARLGLAMQMMFL-GGKERTKKEWESLIYKAGFSDYKIIPIVAAESIIVAYP 89
            E     +  +L   + MM L  G+ERT+KEWE+L  +AGF  YKI P+    S+I  +P
Sbjct: 299  EEAANMTEVKLIFDVLMMVLVTGRERTEKEWENLFLEAGFMSYKITPLFGLRSLIEVFP 357


>gb|AAP45313.1| S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclaurine
            4'-O-methyltransferase 1 [Papaver somniferum]
          Length = 354

 Score =  230 bits (587), Expect = 8e-58
 Identities = 135/359 (37%), Positives = 211/359 (58%), Gaps = 4/359 (1%)
 Frame = -1

Query: 1153 GNLAMTEEQEEEMKAKVQLGKHMYAFAETITLRCAVQLGIPDQI-HKHGPLTLSELASKL 977
            G+    E  E ++K + QL   +Y +A+++ LRC V++GI D I + +G +TLSEL SKL
Sbjct: 2    GSSIDAETHEVDIKDQAQLWNIIYGYADSLVLRCTVEIGIADIIKNNNGSITLSELVSKL 61

Query: 976  QIESINMDRFELTMRYMVHMNLLTAIADEANGETKYGLTPASKLLLKSSHNNNKSLASFV 797
             + ++N D     +RY+VH+N+L      A  +  Y L P   LLLK S    +S+A  +
Sbjct: 62   PLSNVNSDNLYRLLRYLVHLNILGQQTCAAGVDRVYSLKPVGTLLLKDSE---RSMAPVI 118

Query: 796  MVQTDPEELFVSRHLVESLG-GAKSCWELFYGVPVNEKLEKDEKWSRMSD-GMNGYTLCM 623
            +  +  + LFV   + E LG G+ + +E   G+ + + LE +   S++ D G  G T  +
Sbjct: 119  LGLSQKDFLFVWNFVKEGLGTGSTTAFEKAMGMDMWKYLEVNPNQSQLFDEGQAGETRLL 178

Query: 622  VEAIVDGLKREKVIDQSVTSLVDVGGNTGVVAKAILSAFPHLKCTVMDFPHVVECVPKDP 443
             + ++   +      Q + SLVDVGG  G   KAI  AFPH+KCT+ D PHV+      P
Sbjct: 179  TKTLLVDCRDTF---QGMDSLVDVGGGNGTTIKAIHEAFPHIKCTLYDLPHVIANSDDHP 235

Query: 442  PLDFVGGDMFDTIPSADIVFFKSMFHGFEDDMCIKILNKCKEAMSPAKGKVILVEMVVDI 263
             +  V GDMF ++PSA ++  K + H + D+ C+ IL KCKEA+    GKVI+V++ ++ 
Sbjct: 236  NILKVPGDMFMSVPSAQVLLLKCVLHDWTDEHCVNILKKCKEAIPKETGKVIIVDVALEE 295

Query: 262  ETMLEFSSARLGLAMQMMF-LGGKERTKKEWESLIYKAGFSDYKIIPIVAAESIIVAYP 89
            E+  E + ARL L + M+   GG+ERT ++WE+L+ +AGF  +KI PI A +S+I A+P
Sbjct: 296  ESEHELTKARLILDIDMLVNTGGRERTAEDWENLLKRAGFRSHKIRPIRAIQSVIEAFP 354


>gb|AAU20765.1| (S)-norcoclaurine 6-O-methyltransferase [Thalictrum flavum subsp.
            glaucum]
          Length = 350

 Score =  229 bits (584), Expect = 2e-57
 Identities = 128/352 (36%), Positives = 206/352 (58%), Gaps = 6/352 (1%)
 Frame = -1

Query: 1126 EEEMKAKVQLGKHMYAFAETITLRCAVQLGIPDQIHKHG-PLTLSELASKLQIESINMDR 950
            +E + ++ +L   +Y FA+++ L+ AVQL + + IH HG P+TLSEL+  L  + +N D 
Sbjct: 6    KENLSSQAKLWNFIYGFADSLVLKSAVQLDLANIIHNHGSPMTLSELSLHLPSQPVNQDA 65

Query: 949  FELTMRYMVHMNLLTAIADEANGETKYGLTPASKLLLKSSHNNNKSLASFVMVQTDPEEL 770
                +RY+VHM L T      +GE +YGL P +K L+K     +K +   ++  TD + +
Sbjct: 66   LYRVLRYLVHMKLFTK--SSIDGELRYGLAPPAKFLVKGW---DKCMLGAILTITDKDFM 120

Query: 769  FVSRHLVESL---GGAKSCWELFYGVPVNEKL-EKDEKWSRMSDGMNGYTLCMVEAIVDG 602
                +L E +   G   + +E   G  + + + E  EK    ++GM   T  ++ A+V  
Sbjct: 121  APWHYLKEGILNDGSTSTAFEKALGTNIWDYMAEHPEKNQLFNEGMANDTRLIMSALV-- 178

Query: 601  LKREKVIDQSVTSLVDVGGNTGVVAKAILSAFPHLKCTVMDFPHVVECVPKDPPLDFVGG 422
             K    +   +T++VDVGG TG   + I  AFPH+KCTV D PHV+   P    ++ + G
Sbjct: 179  -KECSSMFDGITTIVDVGGGTGTAVRNIAKAFPHIKCTVYDLPHVIADSPGYTEINSIQG 237

Query: 421  DMFDTIPSADIVFFKSMFHGFEDDMCIKILNKCKEAMSPAKGKVILVEMVVDIETMLEFS 242
            DMF  IP+AD +  K + H ++D  CI+IL +CK+A+    GKVI++++++D+++   ++
Sbjct: 238  DMFKYIPNADAIMMKCILHDWDDKECIEILKRCKDAVPRDGGKVIIIDIILDVKSEHPYT 297

Query: 241  SARLGLAMQMMF-LGGKERTKKEWESLIYKAGFSDYKIIPIVAAESIIVAYP 89
              RL L + MM   GGKERT++EW+ LI+ AG+  YKI  I A +S+I AYP
Sbjct: 298  KMRLTLDLDMMLNTGGKERTEEEWKKLIHDAGYKGYKITHISAVQSVIEAYP 349


>emb|CAN75970.1| hypothetical protein VITISV_009881 [Vitis vinifera]
          Length = 354

 Score =  229 bits (583), Expect = 2e-57
 Identities = 146/355 (41%), Positives = 208/355 (58%), Gaps = 8/355 (2%)
 Frame = -1

Query: 1129 QEEEMKAKVQLGKHMYAFAETITLRCAVQLGIPDQIHKHG-PLTLSELASKLQIESINMD 953
            + E  +A+  + KH+++F ++++L+CAVQLGIPD IH H  P+TL ELAS +Q+      
Sbjct: 9    RSELFEAQSFIYKHVFSFMDSMSLKCAVQLGIPDAIHNHNQPITLPELASAIQVPPEKTS 68

Query: 952  RFELTMRYMVHMNLLTAIADEANGETKYGLTPASKLLLKSSHNNNKSLASFVMVQTDPEE 773
            R    MR +VH         + N E  Y LTP S+LL+K    N  SLA  V+   DP  
Sbjct: 69   RLHQLMRLLVHSGFFAMQKVDENQEG-YVLTPPSRLLVKG---NATSLAPIVLGMLDPV- 123

Query: 772  LFVSRHLVESL--GGAKSCWELFYGVPV-NEKLEKDEKWSRMSDGMNGYTLCMVEAIVDG 602
            L    H + S   G + + +E  +G+ + N   +  E +S + + M   +  M  AI   
Sbjct: 124  LVTPWHFLGSWLQGSSLTAFEAAHGMDLWNYGNQNPEXFSXIGEIMATDSRMMSLAI--- 180

Query: 601  LKREKVIDQSVTSLVDVGGNTGVVAKAILSAFPHLKCTVMDFPHVVECVPKDPPLDFVGG 422
             +  K I +  +SLVDVGG TG +A+ I  AFPHLKCTV+D P VV  +PK   LD+VGG
Sbjct: 181  -RECKEIFEGXSSLVDVGGGTGTMARGICEAFPHLKCTVLDLPQVVANLPKSENLDYVGG 239

Query: 421  DMFDTIPSADIVFFKSMFHGFEDDMCIKILNKCKEAM--SPAKGKVILVEMVV-DIETML 251
            DMF +IPSAD +F KS+ H + D+ C+KIL +C+EA+  S   GKVI++++V+ + +   
Sbjct: 240  DMFQSIPSADAIFIKSVLHNWGDEDCVKILKRCREAIPSSAEGGKVIIIDLVLSNKKDEH 299

Query: 250  EFSSARLGLAMQMMFL-GGKERTKKEWESLIYKAGFSDYKIIPIVAAESIIVAYP 89
            E +  +L   M MM L  GKER ++EWE L  +AGFS YKI P     S+I  YP
Sbjct: 300  ELAKTKLFNDMMMMVLVAGKERCEEEWEKLFLEAGFSHYKITPRFGVLSLIEVYP 354


>ref|XP_002278127.1| PREDICTED: isoflavone-7-O-methyltransferase 9 [Vitis vinifera]
          Length = 354

 Score =  228 bits (582), Expect = 3e-57
 Identities = 146/355 (41%), Positives = 209/355 (58%), Gaps = 8/355 (2%)
 Frame = -1

Query: 1129 QEEEMKAKVQLGKHMYAFAETITLRCAVQLGIPDQIHKHG-PLTLSELASKLQIESINMD 953
            + E  +A+  + KH+++F ++++L+CAVQLGIPD IH H  P+TL ELAS +Q+      
Sbjct: 9    RSELFEAQSFIYKHVFSFMDSMSLKCAVQLGIPDAIHNHNQPITLPELASAIQVPPEKTS 68

Query: 952  RFELTMRYMVHMNLLTAIADEANGETKYGLTPASKLLLKSSHNNNKSLASFVMVQTDPEE 773
            R    MR +VH         + N E  Y LTP S+LL+K    N  SLA  V+   DP  
Sbjct: 69   RLHQLMRLLVHSGFFAMQKVDENQEG-YVLTPPSRLLVKG---NATSLAPIVLGMLDPV- 123

Query: 772  LFVSRHLVESL--GGAKSCWELFYGVPV-NEKLEKDEKWSRMSDGMNGYTLCMVEAIVDG 602
            L    H + S   G + + +E  +G+ + N   +  E +S + + M   +  M  AI   
Sbjct: 124  LVTPWHFLGSWLQGSSLTAFEAAHGMDLWNYGNQNPEFFSLIGEIMATDSRMMSLAI--- 180

Query: 601  LKREKVIDQSVTSLVDVGGNTGVVAKAILSAFPHLKCTVMDFPHVVECVPKDPPLDFVGG 422
             +  K I + ++SLVDVGG TG +A+ I  AFPHLKCTV+D P VV  +PK   LD+VGG
Sbjct: 181  -RECKEIFEGLSSLVDVGGGTGTMARGICEAFPHLKCTVLDLPQVVANLPKSENLDYVGG 239

Query: 421  DMFDTIPSADIVFFKSMFHGFEDDMCIKILNKCKEAM--SPAKGKVILVEMVV-DIETML 251
            DMF +IPSAD +F KS+ H + D+ C+KIL +C+EA+  S   GKVI++++V+ + +   
Sbjct: 240  DMFQSIPSADAIFIKSVLHNWGDEDCVKILKRCREAIPSSAEGGKVIIIDLVLSNKKDEH 299

Query: 250  EFSSARLGLAMQMMFL-GGKERTKKEWESLIYKAGFSDYKIIPIVAAESIIVAYP 89
            E +  +L   M MM L  GKER ++EWE L  +AGFS YKI P     S+I  YP
Sbjct: 300  ELAKTKLFNDMMMMVLVAGKERCEEEWEKLFLEAGFSHYKITPRFGVLSLIEVYP 354


>sp|Q9LEL6.1|6OMT_COPJA RecName: Full=(RS)-norcoclaurine 6-O-methyltransferase; AltName:
            Full=S-adenosyl-L-methionine:norcoclaurine
            6-O-methyltransferase; Short=6-OMT
            gi|9711914|dbj|BAB08004.1|
            S-adenosyl-L-methionine:norcoclaurine
            6-O-methyltransferase [Coptis japonica]
          Length = 347

 Score =  228 bits (581), Expect = 4e-57
 Identities = 132/353 (37%), Positives = 206/353 (58%), Gaps = 4/353 (1%)
 Frame = -1

Query: 1135 EEQEEEMKAKVQLGKHMYAFAETITLRCAVQLGIPDQIHKHGP-LTLSELASKLQIESIN 959
            E +++ + ++ +L   +Y FAE++ L+CAVQL + + IH  G  +TLSEL+S+L  + +N
Sbjct: 2    EVKKDNLSSQAKLWNFIYGFAESLVLKCAVQLDLANIIHNSGTSMTLSELSSRLPSQPVN 61

Query: 958  MDRFELTMRYMVHMNLLTAIADEANGETKYGLTPASKLLLKSSHNNNKSLASFVMVQTDP 779
             D     MRY+VHM L T  +   +GE +YGL P +K L+K     +K +   ++  TD 
Sbjct: 62   EDALYRVMRYLVHMKLFTKAS--IDGELRYGLAPPAKYLVKGW---DKCMVGSILAITDK 116

Query: 778  EELFVSRHLVESLGGAK-SCWELFYGVPV-NEKLEKDEKWSRMSDGMNGYTLCMVEAIVD 605
            + +    +L + L G   + +E   G  +     E  EK    ++ M   +  ++ A+V 
Sbjct: 117  DFMAPWHYLKDGLSGESGTAFEKALGTNIWGYMAEHPEKNQLFNEAMANDSRLIMSALV- 175

Query: 604  GLKREKVIDQSVTSLVDVGGNTGVVAKAILSAFPHLKCTVMDFPHVVECVPKDPPLDFVG 425
              K    I   +T+LVDVGG TG   + I +AFPH+KCTV D PHV+   P    +  V 
Sbjct: 176  --KECGNIFNGITTLVDVGGGTGTAVRNIANAFPHIKCTVYDLPHVIADSPGYSEVHCVA 233

Query: 424  GDMFDTIPSADIVFFKSMFHGFEDDMCIKILNKCKEAMSPAKGKVILVEMVVDIETMLEF 245
            GDMF  IP AD +  K + H ++D  CI+IL +CKEA+    GKVI+V++V+++++   +
Sbjct: 234  GDMFKFIPKADAIMMKCILHDWDDKECIEILKRCKEAVPVKGGKVIIVDIVLNVQSEHPY 293

Query: 244  SSARLGLAMQMMF-LGGKERTKKEWESLIYKAGFSDYKIIPIVAAESIIVAYP 89
            +  RL L + MM   GGKERT++EW+ LI+ AG+  +KI  I A +S+I AYP
Sbjct: 294  TKMRLTLDLDMMLNTGGKERTEEEWKKLIHDAGYKGHKITQITAVQSVIEAYP 346


>gb|ACO90232.1| putative norcoclaurine 6-O-methyltransferase [Papaver bracteatum]
          Length = 346

 Score =  228 bits (581), Expect = 4e-57
 Identities = 135/353 (38%), Positives = 201/353 (56%), Gaps = 9/353 (2%)
 Frame = -1

Query: 1120 EMKAKVQLGKHMYAFAETITLRCAVQLGIPDQIHKH-GPLTLSELASKLQI-ESINMDRF 947
            + + + ++ K +Y FAE++ L+CAVQL I + +H +  P++LSELASKL + + +N DR 
Sbjct: 8    DQQNQAKIWKQIYGFAESLVLKCAVQLEIAETLHNNVKPMSLSELASKLPVPQPVNEDRL 67

Query: 946  ELTMRYMVHMNLLTAIADEANGETKYGLTPASKLLLKSSHNNNKSLASFVMVQTDPEELF 767
               MRY+VHM L    A       KY L P +K LL+      KS+   ++   D + L 
Sbjct: 68   FRIMRYLVHMELFKIDATTQ----KYSLAPPAKYLLRGWE---KSMVDSILCINDKDFLA 120

Query: 766  VSRHLVESLGGAKSCWELFYG----VPVNEKLEKDEKWSRMSDGMNGYTLCMVEAIVDGL 599
               HL + L G    +E   G    V ++E  EK++ +       N    C    +   L
Sbjct: 121  PWHHLGDGLTGNCDAFEKALGKSIWVYMSENPEKNQLF-------NAAMACDTRLVTSAL 173

Query: 598  KRE--KVIDQSVTSLVDVGGNTGVVAKAILSAFPHLKCTVMDFPHVVECVPKDPPLDFVG 425
              E   +    + +LVDVGG TG   K I  AFP +KCT+ D PHV+   P+ P +  + 
Sbjct: 174  ANECKSIFSDGIKTLVDVGGGTGTAVKTISKAFPDIKCTIYDLPHVIADSPEIPNITKIS 233

Query: 424  GDMFDTIPSADIVFFKSMFHGFEDDMCIKILNKCKEAMSPAKGKVILVEMVVDIETMLEF 245
            GDMF +IPSAD +F K + H + D+ CI+IL +CKEA+ P  GKVI+V++V+D+++   +
Sbjct: 234  GDMFKSIPSADAIFMKCILHDWNDEECIQILKRCKEAL-PKDGKVIIVDVVIDMDSTHPY 292

Query: 244  SSARLGLAMQMMF-LGGKERTKKEWESLIYKAGFSDYKIIPIVAAESIIVAYP 89
            +  RL L + MM   GGKERTK+EW+ L   AGF+ +K+  I A +S+I AYP
Sbjct: 293  AKIRLTLDLDMMLNTGGKERTKEEWKILFDAAGFASHKVTQISAVQSVIEAYP 345


>ref|XP_004232928.1| PREDICTED: trans-resveratrol di-O-methyltransferase-like [Solanum
            lycopersicum]
          Length = 357

 Score =  228 bits (580), Expect = 5e-57
 Identities = 139/361 (38%), Positives = 210/361 (58%), Gaps = 16/361 (4%)
 Frame = -1

Query: 1123 EEMKAKVQLGKHMYAFAETITLRCAVQLGIPDQIHKHG-PLTLSELASKLQIESINMDRF 947
            E  +A+  + KH ++FA ++ L CA+QLGIPD IH H  P+TLS+L S L++     D  
Sbjct: 8    EMFEAQAHIYKHAFSFANSMVLGCAIQLGIPDVIHSHKQPMTLSQLVSHLKLPLEKSDAI 67

Query: 946  ELTMRYMVHMNLL--TAIADEANGETKYG--LTPASKLLLKSSHNNNKSLASFVMVQTDP 779
               MR +V+      T   DE N E++ G  LTP+SKLLLKS   N   L+ F     DP
Sbjct: 68   HRLMRLLVYSGFFATTDFLDE-NSESQQGYVLTPSSKLLLKSEIPN---LSPFARAMIDP 123

Query: 778  EELFVSRHLVE-SLGGAKSCWELFYGVPVNEKLEKDEKWSRMSD---GMNGYTLCMVEAI 611
              +   + L +  LG   + +E  +G P+ +  +++ ++S + +     +   +C+V   
Sbjct: 124  VMVNPWQSLGDWFLGNETTPFETAHGAPMWKFCDQNPRFSNVFNEAMASDSQMMCLV--- 180

Query: 610  VDGLKREKVIDQSVTSLVDVGGNTGVVAKAILSAFPHLKCTVMDFPHVVECVPKDPPLDF 431
               +K  K + Q + SLVDVGG TG++A  IL+AFPHLKCTV+D PHVV  +P    L +
Sbjct: 181  ---VKDCKQVFQEIDSLVDVGGGTGIIANTILAAFPHLKCTVLDLPHVVANMPDTENLKY 237

Query: 430  VGGDMFDTIPSADIVFFKSMFHGFEDDMCIKILNKCKEAMSP----AKGKVILVEMVVDI 263
            VGGDMF +IPSAD + F  + H + D+ C+KIL +C EA+       KGKV++++MV+D 
Sbjct: 238  VGGDMFHSIPSADAILFMHVMHNWSDENCVKILKRCGEAIKDKNEGRKGKVLIIDMVLDR 297

Query: 262  ETMLEFSSARLGL---AMQMMFLGGKERTKKEWESLIYKAGFSDYKIIPIVAAESIIVAY 92
            +   E +   + L    + M+ + G++RT+KEWE L  +AGF  YKI P+    S+I  +
Sbjct: 298  DKE-EANMTEVKLIFDVLMMVLVTGRQRTEKEWEKLFLEAGFMSYKITPLFGLRSLIEVF 356

Query: 91   P 89
            P
Sbjct: 357  P 357


>ref|XP_006364329.1| PREDICTED: uncharacterized protein LOC102587683 [Solanum tuberosum]
          Length = 829

 Score =  227 bits (578), Expect = 9e-57
 Identities = 137/364 (37%), Positives = 210/364 (57%), Gaps = 16/364 (4%)
 Frame = -1

Query: 1132 EQEEEMKAKVQLGKHMYAFAETITLRCAVQLGIPDQIHKHG-PLTLSELASKLQIESINM 956
            ++E   + +  + KH ++FA ++ L CA+QLGIPD IH H  P+TLS+L S+L++     
Sbjct: 477  DKEWMFQGQAHIYKHAFSFANSMVLGCAIQLGIPDVIHSHKQPMTLSQLVSELKLPPAKS 536

Query: 955  DRFELTMRYMVHMNLL----TAIADEANGETKYGLTPASKLLLKSSHNNNKSLASFVMVQ 788
            D     MR +V+        T + DE   +  Y LTP+SKLLLKS   N   L+ +V   
Sbjct: 537  DAIHRLMRLLVYSGFFATTNTILLDE--NQQGYILTPSSKLLLKSEIPN---LSPYVRAI 591

Query: 787  TDPEELFVSRHLVE--SLGGAKSCWELFYGVPVNEKLEKDEKWSRMSD---GMNGYTLCM 623
             DP  +   + L +   LG   + +E  +G P+ E   ++ +++ + +     +   +C+
Sbjct: 592  VDPVSVNPWQSLGDWFLLGNETTPFETAHGAPMWEFFHQNPRFNNVFNEAMASDSQMMCL 651

Query: 622  VEAIVDGLKREKVIDQSVTSLVDVGGNTGVVAKAILSAFPHLKCTVMDFPHVVECVPKDP 443
            V      +K  K + Q + SLVDVGG TG++A  IL+AFPHLKCTV+D PHVV  +    
Sbjct: 652  V------VKDCKEVFQDMDSLVDVGGGTGIIANTILAAFPHLKCTVLDLPHVVANMSDTH 705

Query: 442  PLDFVGGDMFDTIPSADIVFFKSMFHGFEDDMCIKILNKCKEAMSP----AKGKVILVEM 275
             L +VGGDMF +IPSAD + FK + H + D+ C+KIL +C+EA+       KGKV++++M
Sbjct: 706  NLKYVGGDMFHSIPSADAILFKHVLHNWSDEDCVKILKRCREAIEDKNEGRKGKVLIIDM 765

Query: 274  VVD-IETMLEFSSARLGLAMQMMFLG-GKERTKKEWESLIYKAGFSDYKIIPIVAAESII 101
            V+D  E     +  +L   + MM +  G++RT+KEWE L  +AGF  YKI P+    S+I
Sbjct: 766  VLDRDEEEANMTEVKLIFDVAMMVVATGRQRTEKEWEKLFIEAGFMSYKITPLFGLRSLI 825

Query: 100  VAYP 89
              +P
Sbjct: 826  QVFP 829


>ref|XP_006858228.1| hypothetical protein AMTR_s00062p00190100 [Amborella trichopoda]
            gi|548862331|gb|ERN19695.1| hypothetical protein
            AMTR_s00062p00190100 [Amborella trichopoda]
          Length = 353

 Score =  227 bits (578), Expect = 9e-57
 Identities = 144/357 (40%), Positives = 208/357 (58%), Gaps = 8/357 (2%)
 Frame = -1

Query: 1135 EEQEEEMKAKVQLGKHMYAFAETITLRCAVQLGIPDQIHKHG-PLTLSELASKLQIESIN 959
            ++ +EE++A+  + +HM+  A+T+ L CAV+LG+ D IH HG P+TL  LAS L I+ +N
Sbjct: 10   QQGKEEVEAQAVIWEHMFGMAKTMALNCAVRLGLADIIHAHGRPITLFHLASLLPIQPVN 69

Query: 958  MDRFELTMRYMVHMNLLTAIADEANGETKYGLTPASKLLLKSSHNNNKSLASFVMVQTDP 779
             DR    MR++VH +L          E  Y LTP+S+LLL+ +    KS++ F  V    
Sbjct: 70   PDRLHRLMRFLVHTHLFAKTTGLNGDEETYWLTPSSQLLLRHAE---KSMSGFARVH--- 123

Query: 778  EELFVSRHLVESLG-----GAKSCWELFYGVPVNEKLEKDEKWSR-MSDGMNGYTLCMVE 617
             E+ VS  L  SLG     G  S +E  YG+   E        +R  ++ M      ++ 
Sbjct: 124  -EMTVSPWL--SLGPCLEEGVASAFEKTYGMSRWEYSASHPDENRAFNEAMACLARLVMP 180

Query: 616  AIVDGLKREKVIDQSVTSLVDVGGNTGVVAKAILSAFPHLKCTVMDFPHVVECVPKDPPL 437
            AIV G +R   + Q   S+VDVGG TG    A+  AFP +K T+ D PHVV  V +   +
Sbjct: 181  AIVGGCER---LLQGARSVVDVGGGTGTAVGALAKAFPSVKFTLYDLPHVVATVGELNGV 237

Query: 436  DFVGGDMFDTIPSADIVFFKSMFHGFEDDMCIKILNKCKEAMSPAKGKVILVEMVVDIET 257
            D VGGDMF  IP AD+VF   + H + D  C++IL + ++A+ P +GKVI+V++V+  E 
Sbjct: 238  DTVGGDMFSAIPKADVVFLMRILHDWGDKECLEILKQIRKAI-PEEGKVIIVDVVLKEEE 296

Query: 256  MLEFSSARLGLAMQMMF-LGGKERTKKEWESLIYKAGFSDYKIIPIVAAESIIVAYP 89
               F  AR+GL M MM   GGKER + EW  L++ AGF  Y+++PI+A  SIIVA+P
Sbjct: 297  EHVFRHARMGLDMVMMVQTGGKERDEGEWAKLLHDAGFKKYEVVPIMAVYSIIVAFP 353


>ref|XP_006364328.1| PREDICTED: trans-resveratrol di-O-methyltransferase-like [Solanum
            tuberosum]
          Length = 354

 Score =  226 bits (577), Expect = 1e-56
 Identities = 139/360 (38%), Positives = 207/360 (57%), Gaps = 15/360 (4%)
 Frame = -1

Query: 1123 EEMKAKVQLGKHMYAFAETITLRCAVQLGIPDQIHKHG-PLTLSELASKLQIESINMDRF 947
            E  + +  + KH  ++A  + L CA+QLGIPD IH H  P+TLS+L S+L++     D  
Sbjct: 4    EMFQGQAHIYKHALSYANCMVLSCAIQLGIPDVIHSHKQPMTLSQLVSQLKLPPQKSDAV 63

Query: 946  ELTMRYMVHMNLLTA---IADEANGETKYGLTPASKLLLKSSHNNNKSLASFVMVQTDPE 776
               MR +V+         + + +  +  Y LTP+SKLLLKS   N   L++FV    +P 
Sbjct: 64   YRVMRLLVYSGFFATRDFLDENSENQQGYILTPSSKLLLKSEIPN---LSTFVRAMVEPA 120

Query: 775  ELFVSRHLVE-SLGGAKSCWELFYGVPVNEKLEKDEKWSRMSD---GMNGYTLCMVEAIV 608
             +   + L +  LG   + +E   G P+ E  +++ +++ + +     +   +C+V    
Sbjct: 121  MVNPWQSLGDWFLGDKTTPFETANGAPIWEFGDQNPRFNNVFNEAMASDSQMMCLVA--- 177

Query: 607  DGLKREKVIDQSVTSLVDVGGNTGVVAKAILSAFPHLKCTVMDFPHVVECVPKDPPLDFV 428
               K  K + Q + SLVDVGG TGV+AKAIL+AFPHLKCTV+D P VV  +P    L +V
Sbjct: 178  ---KDCKQVFQDMNSLVDVGGGTGVIAKAILAAFPHLKCTVLDLPQVVANMPDTNNLKYV 234

Query: 427  GGDMFDTIPSADIVFFKSMFHGFEDDMCIKILNKCKEAMSPAK---GKVILVEMVVD--- 266
            GGDMF +IPSAD + FK + H + D+ C+KIL KC+EA+   K   GKVI+++MV+D   
Sbjct: 235  GGDMFHSIPSADAILFKHVMHNWSDEDCVKILKKCREAIKDNKKNEGKVIIIDMVLDRDE 294

Query: 265  IETMLEFSSARLGLAMQM-MFLGGKERTKKEWESLIYKAGFSDYKIIPIVAAESIIVAYP 89
             E     +  +L   + M + L G+ERT+KEWE L  +AGF  YKI P+    S+I  +P
Sbjct: 295  DEDKANMTEVKLIYDVAMIVLLTGRERTEKEWEKLFLEAGFMTYKITPLFGLRSLIEIFP 354


>gb|ACO90250.1| norcoclaurine 6-O-methyltransferase-like protein [Thalictrum flavum]
          Length = 346

 Score =  225 bits (574), Expect = 3e-56
 Identities = 128/352 (36%), Positives = 209/352 (59%), Gaps = 7/352 (1%)
 Frame = -1

Query: 1123 EEMKAKVQLGKHMYAFAETITLRCAVQLGIPDQIHKHG-PLTLSELASKLQIESINMDRF 947
            E++ ++ +L  ++Y FA+++ L+CAVQL + + IH HG P+TLSEL+S+L  + +N D  
Sbjct: 2    EDLSSQAKLWNYIYGFADSLVLKCAVQLDLANIIHDHGTPMTLSELSSRLPSQPVNQDAL 61

Query: 946  ELTMRYMVHMNLLTAIADEANGETKYGLTPASKLLLKSSHNNNKSLASFVMVQTDPEELF 767
               MRY+VH+ L T      +GE +YGL P +K L+K   N    +   +++  D + + 
Sbjct: 62   YRVMRYLVHIKLFTK--SSIDGELRYGLAPPAKFLVKGWDN---CMIGSILLMVDTDFMA 116

Query: 766  VSRHLVESL---GGAKSCWELFYGVPVNEKL-EKDEKWSRMSDGMNGYTLCMVEAIVDGL 599
               ++ + +   G + + +E   G  + E L E  EK    ++GM   +   +  +   +
Sbjct: 117  PYHYIKDEILNDGSSITAFEKASGTNIWEYLAEHPEKNQLFNEGMANESRLTMSGL---M 173

Query: 598  KREKVIDQSVTSLVDVGGNTGVVAKAILSAFPHLKCTVMDFPHVVECVPKDPPLDFVGGD 419
            K      + +T+LVDVGG TG   K I  AFP++K TV D PHV+   P D  ++FV GD
Sbjct: 174  KDCSSTFEGLTTLVDVGGGTGTTVKYIAKAFPNIKYTVYDLPHVIADAPGDTEINFVEGD 233

Query: 418  MFDTIPSADIVFFKSMFHGFEDDMCIKILNKCKEAMSPAKGKVILVEMVVDIETMLEFSS 239
            MF  IP+AD +  K + H ++D+ CI+IL +CK+A+    GKVI++++V+++++   ++ 
Sbjct: 234  MFKYIPNADAILMKGVLHDWDDNECIEILKRCKDAVPRDGGKVIIIDVVLNVKSEHPYTK 293

Query: 238  ARLGLAMQMMFLG-GKERTKKEWESLIY-KAGFSDYKIIPIVAAESIIVAYP 89
             RL L + MM    GKERT+++W+ LIY  AG+  YKI  I A +S+I AYP
Sbjct: 294  MRLTLDLDMMLNNKGKERTEEDWKKLIYDDAGYKGYKITQISALQSVIEAYP 345


>gb|ACO90225.1| putative norcoclaurine 6-O-methyltransferase [Papaver bracteatum]
          Length = 357

 Score =  225 bits (574), Expect = 3e-56
 Identities = 139/362 (38%), Positives = 208/362 (57%), Gaps = 15/362 (4%)
 Frame = -1

Query: 1141 MTEEQEEEMKAKVQLGKHMYAFAETITLRCAVQLGIPDQIHKHG-PLTLSELASKLQIES 965
            M    + + + +  + K +Y FAE++ L+CAVQL I + IH HG P++LSELASKL I+ 
Sbjct: 1    MEAVSQTDQENQAIIWKQIYGFAESLVLKCAVQLEIAETIHNHGKPMSLSELASKLPIDQ 60

Query: 964  -INMDRFELTMRYMVHMNL-----LTAIADEANG--ETKYGLTPASKLLLKSSHNNNKSL 809
             +N+DR    MR++VHM L     ++ ++ E     E KY L P +K L++ S    +S+
Sbjct: 61   PVNIDRLYRVMRFLVHMKLFNKENISILSGETAQVVEDKYSLAPPAKYLIRGSE---QSM 117

Query: 808  ASFVMVQTDPEELFVSRHLVESLGGAKSCWELFYGVPVNEKLEKDEKWSRMSDGMNGYTL 629
              +V+  TD + +     L E + G  + +E   G    + + ++ K ++M    N    
Sbjct: 118  VPWVLGITDEDLVAPWHWLKEGITGNCNVFEKVLGKSHADYMSENPKKNQM---FNELMA 174

Query: 628  CMVEAIVDGLKRE--KVIDQSVTSLVDVGGNTGVVAKAILSAFPHLKCTVMDFPHVVECV 455
            C    +   L  E   V    + +LVDVGG TG    AI  AFP+++CT+ D PHV+   
Sbjct: 175  CDSRLVTSALVNECRSVFSDGINTLVDVGGGTGTAVSAISKAFPNIQCTLFDLPHVIGDS 234

Query: 454  PKDPPLDFVGGDMFDTIPSADIVFFKSMFHGFEDDMCIKILNKCKEAMSPAKGKVILVEM 275
            P+ P +    GDMF +IPSAD +F K++ H + DD C++IL +CKE +S   GKVILVEM
Sbjct: 235  PEIPNVTKTSGDMFQSIPSADAIFMKNILHDWNDDECVQILKRCKEVVS-VGGKVILVEM 293

Query: 274  VVDIETMLEFSSARLGLAMQMMF-LGGKERTKKEWESLIYKAGFSDYKIIPI---VAAES 107
            V+D E    +S  RL L + M+   GGKE T++EW+ LIY AGF+ YKI  +    AA+S
Sbjct: 294  VMDTELAHPYSKLRLTLDLDMLVNNGGKEGTEEEWKKLIYAAGFTSYKITQMSAGFAAQS 353

Query: 106  II 101
            +I
Sbjct: 354  VI 355


>gb|ABY75613.1| S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclaurine
            4'-O-methyltransferase [Coptis chinensis]
          Length = 350

 Score =  225 bits (573), Expect = 3e-56
 Identities = 128/347 (36%), Positives = 202/347 (58%), Gaps = 3/347 (0%)
 Frame = -1

Query: 1120 EMKAKVQLGKHMYAFAETITLRCAVQLGIPDQIHKHG-PLTLSELASKLQIESINMDRFE 944
            ++KA+  + K +Y FA+++ LRCAV+LGI D +  +  P+ L++LASKL + ++N D   
Sbjct: 11   DIKAQAHVWKIIYGFADSLVLRCAVELGIVDIVDNNNQPMALADLASKLPVSNVNCDNLY 70

Query: 943  LTMRYMVHMNLLTAIADEANGETKYGLTPASKLLLKSSHNNNKSLASFVMVQTDPEELFV 764
              +RY+V M +L  +    +GE KY L P + LL   S N  +S+   ++  T  + +  
Sbjct: 71   RILRYLVKMEILR-VEKSDDGEKKYALEPIATLL---SRNAKRSMVPMILGMTQKDFMTP 126

Query: 763  SRHLVESLGGAKSCWELFYGVPVNEKLEKDEKWSRM-SDGMNGYTLCMVEAIVDGLKREK 587
               + + L    + +E   G+ + E LE     S++ ++GM G T  +  +++ G    +
Sbjct: 127  WHSMKDGLSDNGTAFEKAMGMTIWEYLEGHPDQSQLFNEGMAGETRLLTSSLISG---SR 183

Query: 586  VIDQSVTSLVDVGGNTGVVAKAILSAFPHLKCTVMDFPHVVECVPKDPPLDFVGGDMFDT 407
             + Q + SLVDVGG  G   KAI  AFPH+KCT+ D PHV+      P ++ +GGDMF +
Sbjct: 184  DMFQGIDSLVDVGGGNGTTVKAISDAFPHIKCTLFDLPHVIANSYDHPNIERIGGDMFKS 243

Query: 406  IPSADIVFFKSMFHGFEDDMCIKILNKCKEAMSPAKGKVILVEMVVDIETMLEFSSARLG 227
            +PSA  +  K + H + D+  IKIL +C+ A+    GKVI+V++ +D E+  E SS RL 
Sbjct: 244  VPSAQAILLKLILHDWNDEDSIKILKQCRNAVPKDGGKVIIVDVALDEESDHELSSTRLI 303

Query: 226  LAMQMMF-LGGKERTKKEWESLIYKAGFSDYKIIPIVAAESIIVAYP 89
            L + M+   GGKERTK+ WE ++  AGFS  KI  I A +S+I  +P
Sbjct: 304  LDIDMLVNTGGKERTKEVWEKIVKSAGFSGCKIRHIAAIQSVIEVFP 350


>gb|AAR09603.1| O-methyltransferase [Mentha x piperita]
          Length = 361

 Score =  224 bits (572), Expect = 4e-56
 Identities = 139/361 (38%), Positives = 201/361 (55%), Gaps = 15/361 (4%)
 Frame = -1

Query: 1126 EEEMKAKVQLGKHMYAFAETITLRCAVQLGIPDQIHKHG-PLTLSELASKLQIESINMDR 950
            EE + A+  +  H++++  +++L+ A+QLGIPD IHKHG P+TLS+LA  L I     D 
Sbjct: 12   EELLDAEAHVWNHIFSYINSMSLKSALQLGIPDIIHKHGNPITLSQLADALNINKAKTDG 71

Query: 949  FELTMRYMVHMNLLTAIADEANGETK-YGLTPASKLLLKSSHNNNKSLASFVMVQTDPEE 773
                MR + H      +  E  GE + Y LT AS+LLL+   +   SLA ++    DP  
Sbjct: 72   LFRLMRLLEHSKFFDKVKVEGEGEEEAYSLTRASRLLLRDEPS---SLAPYIRAMLDPNF 128

Query: 772  LFVSRHLVESLGG-AKSCWELFYGVPVNEKLEKDEKWSRMSDGMNGYTLCMVEAIVDGLK 596
            +    HL E LG    S +E  +G  + E    +E+W+++ +        +V +I+  +K
Sbjct: 129  MDPFHHLSEWLGSECPSPFEFKHGRSLWEYAGIEERWNQLFNQAMANDAKLVTSIL--VK 186

Query: 595  REKVIDQSVTSLVDVGGNTGVVAKAILSAFPHLKCTVMDFPHVVECVPKDPPLDFVGGDM 416
              + I Q + SLVDVGG  G VAK +  AFP LK  V+D PHVV  +     L +V GDM
Sbjct: 187  ECRHIFQGLESLVDVGGGAGTVAKVVADAFPGLKAVVLDLPHVVADLATSENLRYVSGDM 246

Query: 415  FDTIPSADIVFFKSMFHGFEDDMCIKILNKCKEAMSPAK----GKVILVEMVV------- 269
            F+ IP AD V  K + H + D+ CIKIL KCKEA++P+K    GKVI+++M++       
Sbjct: 247  FEDIPRADAVLLKWILHNWSDEECIKILEKCKEAITPSKNNNGGKVIVIDMILKDEKQHH 306

Query: 268  -DIETMLEFSSARLGLAMQMMFLGGKERTKKEWESLIYKAGFSDYKIIPIVAAESIIVAY 92
               ET L F        + M  L GKERT+KEW +L + AGF  YKI P++   S+I  +
Sbjct: 307  KGTETQLLFD------VLMMTALTGKERTEKEWANLFFAAGFKTYKIHPVLRLRSVIEIF 360

Query: 91   P 89
            P
Sbjct: 361  P 361


>gb|AAU20768.1| 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase [Thalictrum
            flavum subsp. glaucum]
          Length = 348

 Score =  224 bits (571), Expect = 6e-56
 Identities = 134/348 (38%), Positives = 207/348 (59%), Gaps = 4/348 (1%)
 Frame = -1

Query: 1120 EMKAKVQLGKHMYAFAETITLRCAVQLGIPDQIHKHG-PLTLSELASKLQIESINMDRFE 944
            ++KA+  + K +Y FA+++ LRCAV+LGI D I  +  P+ L++LASKL I ++N+D   
Sbjct: 12   DIKAQAHVWKIIYGFADSLVLRCAVELGIFDIIDNNNQPIPLADLASKLPISNVNLDNLF 71

Query: 943  LTMRYMVHMNLLTAIADEANGETKYGLTPASKLLLKSSHNNNKSLASFVMVQTDPEELFV 764
              +RY+V M LL+  AD+     KY L P +KL+L+   N  +S+   V+  T  + +  
Sbjct: 72   RILRYLVKMELLSYAADD-----KYALEPIAKLVLR---NEKRSMVPMVLGMTQKDFMTP 123

Query: 763  SRHLVESL-GGAKSCWELFYGVPVNEKLEKDEKWSRM-SDGMNGYTLCMVEAIVDGLKRE 590
               + + L     + +E   G+ + E LE     S++ ++GM G T  +  +++ G    
Sbjct: 124  WHSMKDGLTDNGVTAFEKAMGMTIWEYLEGHPDQSQLFNEGMAGETRLLTSSLISG---S 180

Query: 589  KVIDQSVTSLVDVGGNTGVVAKAILSAFPHLKCTVMDFPHVVECVPKDPPLDFVGGDMFD 410
            K + QS+ SLVDVGG  G   KAI  AFPH+KCT+ D PHV+      P ++ +GGDMF 
Sbjct: 181  KDMFQSIDSLVDVGGGNGTTIKAISVAFPHIKCTLFDLPHVIANSYDHPNIERIGGDMFK 240

Query: 409  TIPSADIVFFKSMFHGFEDDMCIKILNKCKEAMSPAKGKVILVEMVVDIETMLEFSSARL 230
             +PSA  +  K + H + D+  IKIL +C++A+    GKVI+V++ +D ++  E SS RL
Sbjct: 241  GMPSAQAILLKLILHDWNDEDSIKILKQCRKAVPKDGGKVIIVDVALDEDSDHELSSTRL 300

Query: 229  GLAMQMMF-LGGKERTKKEWESLIYKAGFSDYKIIPIVAAESIIVAYP 89
             L + M+   GGKERTK++WE L+  AGFS  KI  I A +S+I  +P
Sbjct: 301  ILDIDMLVNTGGKERTKEDWEKLVKCAGFSGCKIRHIAAIQSVIEVFP 348