BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Cocculus22_contig00000372
         (2038 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

dbj|BAF80448.1| corytuberine synthase [Coptis japonica var. diss...   679   0.0  
sp|P47195.1|C80A1_BERST RecName: Full=Berbamunine synthase; AltN...   513   e-142
gb|AGC29949.1| CYP80G3 [Sinopodophyllum hexandrum]                    504   e-140
sp|Q9FXW4.1|C80B2_COPJA RecName: Full=Probable (S)-N-methylcocla...   484   e-134
gb|ABS19627.1| (S)-N-methylcoclaurine-3'-hydroxylase [Coptis chi...   477   e-131
emb|CBI31830.3| unnamed protein product [Vitis vinifera]              464   e-128
gb|ACO90224.1| putative (S)-N-methylcoclaurine 3'-hydroxylase [P...   462   e-127
ref|XP_002274562.1| PREDICTED: probable (S)-N-methylcoclaurine 3...   462   e-127
gb|AAF05621.1|AF191772_1 (S)-N-methylcoclaurine 3'-hydroxylase [...   461   e-127
emb|CAN62647.1| hypothetical protein VITISV_013219 [Vitis vinifera]   461   e-127
gb|AAF61400.1|AF134590_1 (S)-N-methylcoclaurine 3'-hydroxylase [...   459   e-126
ref|XP_002274530.1| PREDICTED: (S)-N-methylcoclaurine 3'-hydroxy...   458   e-126
ref|XP_004234364.1| PREDICTED: (S)-N-methylcoclaurine 3'-hydroxy...   454   e-125
ref|XP_006358914.1| PREDICTED: probable (S)-N-methylcoclaurine 3...   454   e-125
sp|O64900.1|C80B2_ESCCA RecName: Full=(S)-N-methylcoclaurine 3'-...   454   e-125
ref|XP_006358870.1| PREDICTED: probable (S)-N-methylcoclaurine 3...   452   e-124
sp|O64899.1|C80B1_ESCCA RecName: Full=(S)-N-methylcoclaurine 3'-...   451   e-124
ref|XP_006353352.1| PREDICTED: probable (S)-N-methylcoclaurine 3...   450   e-123
emb|CBI34714.3| unnamed protein product [Vitis vinifera]              448   e-123
ref|XP_002283461.1| PREDICTED: probable (S)-N-methylcoclaurine 3...   448   e-123

>dbj|BAF80448.1| corytuberine synthase [Coptis japonica var. dissecta]
          Length = 486

 Score =  679 bits (1752), Expect = 0.0
 Identities = 332/486 (68%), Positives = 408/486 (83%), Gaps = 4/486 (0%)
 Frame = +3

Query: 45   ITLSLLSFIPFVIVLYLLFKPKH-NLPPSPRPSWPLIGNIPAIL-GSKTPLHVTLTDLAQ 218
            + ++L S IP ++V  LL KPK+ NLPP P P WPLIGN+P +   ++ PLH+TL ++A+
Sbjct: 3    LQIALFSLIPVILVFILLLKPKYKNLPPGPHP-WPLIGNLPILFTNTEVPLHITLANMAR 61

Query: 219  VHGPLMVVTLGTAPTVVASTREAAMEILKTHDRALSGRHIAKSFRIKEMNKHSLVWSNCT 398
             HGP+M++ LGT PTV+AST EAAMEILKTHDR  S RHI  SFR+K   K+SLVWS+CT
Sbjct: 62   THGPIMILWLGTQPTVMASTAEAAMEILKTHDRIFSARHIRMSFRLKHHIKYSLVWSDCT 121

Query: 399  DTWKLLRKLARTEIFSPRMLQIQEPVRENKVGELVEFLRGREGKVVKISQFVFGTLLNII 578
            D WKLLRK+ RTEIFSP+MLQ Q  VRE KV EL++FLR +EG+VVKISQFVFGTLLNI+
Sbjct: 122  DYWKLLRKIVRTEIFSPKMLQAQSHVREQKVAELIDFLRSKEGQVVKISQFVFGTLLNIL 181

Query: 579  GNVVFSKDVFLFDD--DKIGMQSLIKELLMIGASPNLAEFYPILEVLDLQGLRRRCADRV 752
            GNVVFSKDVF++ D  DK G+Q+LI+E+LMIGA PN+AEFYP LE LDLQGL+++C +R 
Sbjct: 182  GNVVFSKDVFVYGDETDKGGIQNLIREMLMIGAEPNVAEFYPSLEELDLQGLKKKCDERF 241

Query: 753  SKVNKLWESTVKERRLGRSGDAKDMLDVLLDNGFSDVQINVLFLETFGPGSETSSATIEW 932
             +V K+WE TVKER+  R+ ++KDMLDVLL N F+D QIN LFLETFGPGSETSSATIEW
Sbjct: 242  IRVMKMWEGTVKERKANRNEESKDMLDVLLANDFNDAQINALFLETFGPGSETSSATIEW 301

Query: 933  VMAELIKNPDKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQACVKETMRLHPAAPFLLPH 1112
            V+AELIK+P ++AK+R EL++VVG TS +KE+ +P LPYLQAC+KE MRLHPAAPFLLP 
Sbjct: 302  VIAELIKSPKEMAKVRKELNEVVG-TSTIKESDLPQLPYLQACIKEAMRLHPAAPFLLPR 360

Query: 1113 RAVETCQVMGYTIPQDYQVLVNAYAIGRDPESWKDPSEFRPERFLESNVDYNGNHFEFIP 1292
            RA ETC+VMGYTIP++ QVLVNAYAIGRDP+SWKDPS F PERFLES+VD++G H++FIP
Sbjct: 361  RAAETCEVMGYTIPKNSQVLVNAYAIGRDPKSWKDPSTFWPERFLESDVDFHGAHYQFIP 420

Query: 1293 FGSGRRICIGMPLATRTVPLIVSSLVHNFYWSLPDGKSPEELEMNEILSLSLAIDPSLSI 1472
            FGSGRR C+GMPLATRT+PLIV SLVHN+ + LP G  PE+L+MNE+LSL+LAIDPSL +
Sbjct: 421  FGSGRRTCVGMPLATRTIPLIVGSLVHNYDFGLPGGNRPEDLKMNEMLSLTLAIDPSLCV 480

Query: 1473 IPKVRA 1490
            +PK RA
Sbjct: 481  VPKARA 486


>sp|P47195.1|C80A1_BERST RecName: Full=Berbamunine synthase; AltName:
            Full=(S)-N-methylcoclaurine oxidase [C-O
            phenol-coupling]; AltName: Full=CYPLXXX; AltName:
            Full=Cytochrome P450 80 gi|642386|gb|AAC48987.1|
            cytochrome P-450 CYP80 [Berberis stolonifera]
          Length = 487

 Score =  513 bits (1320), Expect = e-142
 Identities = 255/478 (53%), Positives = 347/478 (72%), Gaps = 5/478 (1%)
 Frame = +3

Query: 69   IPFVIVLY-LLFKPKH-NLPPSPRPSWPLIGNIPAILGSKTPLHVT-LTDLAQVHGPLMV 239
            I  V +LY LLFKPKH NLPPSP P+WP++G++P ++   +P  +  ++++AQ +GPL+ 
Sbjct: 10   ISLVALLYFLLFKPKHTNLPPSP-PAWPIVGHLPDLISKNSPPFLDYMSNIAQKYGPLIH 68

Query: 240  VTLGTAPTVVASTREAAMEILKTHDRALSGRHIAKSFRIKEMNKHSLVWSNCTDTWKLLR 419
            +  G   ++ AST+EAAME+L+T+D+ LSGR     FRIK    +S++WS+    WK  R
Sbjct: 69   LKFGLHSSIFASTKEAAMEVLQTNDKVLSGRQPLPCFRIKPHIDYSILWSDSNSYWKKGR 128

Query: 420  KLARTEIFSPRMLQIQEPVRENKVGELVEFLRGREGKVVKISQFVFGTLLNIIGNVVFSK 599
            K+  TEIFS +MLQ QE  RE   G LV F+  + G VV++  ++FG  LN++G+VVFSK
Sbjct: 129  KILHTEIFSQKMLQAQEKNRERVAGNLVNFIMTKVGDVVELRSWLFGCALNVLGHVVFSK 188

Query: 600  DVFLFDD--DKIGMQSLIKELLMIGASPNLAEFYPILEVLDLQGLRRRCADRVSKVNKLW 773
            DVF + D  D++GM  LI  +LM G   ++A ++P+L   DL GL+R+  ++   + K+W
Sbjct: 189  DVFEYSDQSDEVGMDKLIHGMLMTGGDFDVASYFPVLARFDLHGLKRKMDEQFKLLIKIW 248

Query: 774  ESTVKERRLGRSGDAKDMLDVLLDNGFSDVQINVLFLETFGPGSETSSATIEWVMAELIK 953
            E  V  RR  R+ + KDMLDVL+ N F++ QIN +F+ETFGPGS+T+S  IEW +A+LIK
Sbjct: 249  EGEVLARRANRNPEPKDMLDVLIANDFNEHQINAMFMETFGPGSDTNSNIIEWALAQLIK 308

Query: 954  NPDKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQACVKETMRLHPAAPFLLPHRAVETCQ 1133
            NPDKLAKLR ELD+VVG +S VKE+H   LPYLQACVKETMRL+P    ++PHR +ETCQ
Sbjct: 309  NPDKLAKLREELDRVVGRSSTVKESHFSELPYLQACVKETMRLYPPISIMIPHRCMETCQ 368

Query: 1134 VMGYTIPQDYQVLVNAYAIGRDPESWKDPSEFRPERFLESNVDYNGNHFEFIPFGSGRRI 1313
            VMGYTIP+   V VNA+AIGRDP+ WKDP +F+PERFL+S+++YNG  F+FIPFGSGRRI
Sbjct: 369  VMGYTIPKGMDVHVNAHAIGRDPKDWKDPLKFQPERFLDSDIEYNGKQFQFIPFGSGRRI 428

Query: 1314 CIGMPLATRTVPLIVSSLVHNFYWSLPDGKSPEELEMNEILSLSLAIDPSLSIIPKVR 1487
            C G PLA R +PL+++SLVH F W LPDG   E+L+M E+ +LSL +   L +IPKVR
Sbjct: 429  CPGRPLAVRIIPLVLASLVHAFGWELPDGVPNEKLDMEELFTLSLCMAKPLRVIPKVR 486


>gb|AGC29949.1| CYP80G3 [Sinopodophyllum hexandrum]
          Length = 346

 Score =  504 bits (1298), Expect = e-140
 Identities = 252/348 (72%), Positives = 297/348 (85%), Gaps = 3/348 (0%)
 Frame = +3

Query: 453  MLQIQEPVRENKVGELVEFLRGREGKVVKISQFVFGTLLNIIGNVVFSKDVFLF---DDD 623
            MLQ+QE VRE KV ELVEFL+G+EG+VVKISQ VFGTLLNI+GNV+FSKDVF +   D D
Sbjct: 1    MLQVQEHVREQKVAELVEFLKGKEGQVVKISQLVFGTLLNILGNVIFSKDVFRYVGADGD 60

Query: 624  KIGMQSLIKELLMIGASPNLAEFYPILEVLDLQGLRRRCADRVSKVNKLWESTVKERRLG 803
            K  MQ+LIKE+LMIGA+PNLAEF+PI E  DLQGL++RC  R S+V K+W+ TV+ER++ 
Sbjct: 61   K--MQTLIKEMLMIGAAPNLAEFWPIFEEFDLQGLKKRCNQRFSEVMKMWKGTVEERKVK 118

Query: 804  RSGDAKDMLDVLLDNGFSDVQINVLFLETFGPGSETSSATIEWVMAELIKNPDKLAKLRL 983
            R+ + KDMLDVLL N F+D QIN +FLETFGPGSETSSAT EW +AELIKNP  LAK+R 
Sbjct: 119  RNEEPKDMLDVLLLNDFNDAQINAVFLETFGPGSETSSATSEWALAELIKNPHILAKVRQ 178

Query: 984  ELDQVVGPTSQVKEAHIPLLPYLQACVKETMRLHPAAPFLLPHRAVETCQVMGYTIPQDY 1163
            ELDQVVG  S VKE+ +P LPYLQAC+KETMRLHPAAPFLLPHRAVETC VMGYTIP+D 
Sbjct: 179  ELDQVVGK-STVKESDLPHLPYLQACIKETMRLHPAAPFLLPHRAVETCPVMGYTIPKDT 237

Query: 1164 QVLVNAYAIGRDPESWKDPSEFRPERFLESNVDYNGNHFEFIPFGSGRRICIGMPLATRT 1343
            QVLVN YAIGRDP++WK+P+ F+PERFLES+VDY G HFEFIPFG+GRR C+GMPLATRT
Sbjct: 238  QVLVNIYAIGRDPKTWKEPTTFKPERFLESDVDYYGKHFEFIPFGAGRRQCVGMPLATRT 297

Query: 1344 VPLIVSSLVHNFYWSLPDGKSPEELEMNEILSLSLAIDPSLSIIPKVR 1487
            +PLIVS+LV    WSLPDGK P++L MNE LSLSLA+DP+L++IPK R
Sbjct: 298  IPLIVSNLVQTLDWSLPDGKLPQDLVMNESLSLSLALDPTLTVIPKSR 345


>sp|Q9FXW4.1|C80B2_COPJA RecName: Full=Probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme
            2; AltName: Full=Cytochrome P450 80B2
            gi|9971208|dbj|BAB12433.1|
            (S)-N-methylcoclaurine-3'-hydroxylase [Coptis japonica]
          Length = 488

 Score =  484 bits (1246), Expect = e-134
 Identities = 257/492 (52%), Positives = 348/492 (70%), Gaps = 6/492 (1%)
 Frame = +3

Query: 39   EVITLSLLSFIPFVIVLYLL--FKPKHNLPPSPRPSWPLIGNIPAILGSKTPLHVTLTDL 212
            EV++++++SF   + + ++L   +PK NLPP PRPS P++GN+   LG K   H     L
Sbjct: 2    EVLSIAIVSFSFLLFLFFILRDSRPK-NLPPGPRPS-PIVGNLLQ-LGDKP--HAEFAKL 56

Query: 213  AQVHGPLMVVTLGTAPTVVASTREAAMEILKTHDRALSGRHIAKSFRIKEMNKHSLVWSN 392
            AQ +G L  + LG+   VVAS+  AA EILKTHD+ LSGR++ +SFR+KE  ++S+VWS 
Sbjct: 57   AQKYGELFSLKLGSQTVVVASSPAAAAEILKTHDKILSGRYVFQSFRVKEHVENSIVWSE 116

Query: 393  CTDTWKLLRKLARTEIFSPRMLQIQEPVRENKVGELVEFLRGREGKVVKISQFVFGTLLN 572
            C D WKLLRK+ RTE+F+P+M++ Q  +RE K  E+V+FLRG+EG+VVKI + VFGTL+N
Sbjct: 117  CNDNWKLLRKVCRTELFTPKMIESQSEIREAKAREMVKFLRGKEGEVVKIVEVVFGTLVN 176

Query: 573  IIGNVVFSKDVFLFDDDKIGMQSL---IKELLMIGASPNLAEFYPILEVLDLQGLRRRCA 743
            I GN++FSKDVF  +D   G   L   + +LL +G S N A+++PI+  LDL G RR  A
Sbjct: 177  IFGNLIFSKDVFDLEDPTGGSVELKEHLWKLLDMGNSTNPADYFPIMGKLDLFGQRRAVA 236

Query: 744  DRVSKVNKLWESTVKERRLGRSGDAK-DMLDVLLDNGFSDVQINVLFLETFGPGSETSSA 920
            + + ++  +W   +KERR  +  ++K D +DVLL+ G  D +IN L +E FG G+ETS++
Sbjct: 237  EVLQQIYDVWGVMLKERRGTKGSESKNDFVDVLLNAGLDDQKINALLMELFGAGTETSAS 296

Query: 921  TIEWVMAELIKNPDKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQACVKETMRLHPAAPF 1100
            TIEW + EL K P  ++K+RLEL  VVG  + VKE+ +P LPYLQA VKET+RLHP  P 
Sbjct: 297  TIEWAITELTKKPLVVSKIRLELVNVVGDNT-VKESDLPHLPYLQAFVKETLRLHPPTPL 355

Query: 1101 LLPHRAVETCQVMGYTIPQDYQVLVNAYAIGRDPESWKDPSEFRPERFLESNVDYNGNHF 1280
            LLP RA+ETC VM YTIP++ Q++VNA+AIGRDP++W DP  F+PERFL S+VDY GN F
Sbjct: 356  LLPRRALETCTVMNYTIPKECQIMVNAWAIGRDPKTWDDPLNFKPERFLSSDVDYKGNDF 415

Query: 1281 EFIPFGSGRRICIGMPLATRTVPLIVSSLVHNFYWSLPDGKSPEELEMNEILSLSLAIDP 1460
            E IPFG GRRIC G+PLA++   LIV++LV NF WSLP G S  EL M+E   L+L  DP
Sbjct: 416  ELIPFGGGRRICPGLPLASQFSNLIVATLVQNFEWSLPQGMSTSELSMDEKFGLTLQKDP 475

Query: 1461 SLSIIPKVRALN 1496
             L I+ K RA N
Sbjct: 476  PLLIVLKARASN 487


>gb|ABS19627.1| (S)-N-methylcoclaurine-3'-hydroxylase [Coptis chinensis]
          Length = 488

 Score =  477 bits (1227), Expect = e-131
 Identities = 249/488 (51%), Positives = 341/488 (69%), Gaps = 5/488 (1%)
 Frame = +3

Query: 39   EVITLSLLSFIPFVIVLYLLFKPKH-NLPPSPRPSWPLIGNIPAILGSKTPLHVTLTDLA 215
            EV++++++SF   + + ++L  P+  NLPP PRP  P++GN+   LG K         LA
Sbjct: 2    EVVSIAIVSFSFLLFLFFILRDPRQKNLPPGPRPL-PIVGNLLQ-LGDKP--RAEFAKLA 57

Query: 216  QVHGPLMVVTLGTAPTVVASTREAAMEILKTHDRALSGRHIAKSFRIKEMNKHSLVWSNC 395
            Q +G L  + LG+   VVAS+  AA E+LKTHD+ LSGR++ +SFR+KE  ++S+VWS C
Sbjct: 58   QKYGQLFSLKLGSQTVVVASSPAAAAEVLKTHDKILSGRYVFQSFRVKEHVENSIVWSEC 117

Query: 396  TDTWKLLRKLARTEIFSPRMLQIQEPVRENKVGELVEFLRGREGKVVKISQFVFGTLLNI 575
             D WKLLRK+ RTE+F+P+M++ Q  +RE K  E+V+FLR +EG+VVKI + VFGTL+NI
Sbjct: 118  NDNWKLLRKVCRTELFTPKMIESQSEIREGKAREMVKFLRSKEGEVVKIVEVVFGTLVNI 177

Query: 576  IGNVVFSKDVFLFDDDKIGMQSL---IKELLMIGASPNLAEFYPILEVLDLQGLRRRCAD 746
             GN++FSKDVF  +D   G   L   + +LL +G S N A+++PI+   DL G RR  AD
Sbjct: 178  FGNLIFSKDVFDLEDPTGGSVELKEHLWKLLEMGNSTNPADYFPIMGKYDLFGQRRAVAD 237

Query: 747  RVSKVNKLWESTVKERRLGRSGDAK-DMLDVLLDNGFSDVQINVLFLETFGPGSETSSAT 923
             + ++  +W   +KERR  +  ++  D +DVLL+ G  D +IN L +E FG G+ETS++T
Sbjct: 238  VLQQIYDVWGINLKERRGMKGSESNNDFVDVLLNAGLEDQKINALLMELFGTGTETSAST 297

Query: 924  IEWVMAELIKNPDKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQACVKETMRLHPAAPFL 1103
            IEW + EL K P  ++K+RLEL  VVG  + VKE+ +P LPYLQA VKET+RLHP  P L
Sbjct: 298  IEWAITELTKKPLVVSKIRLELVNVVGDNT-VKESDLPHLPYLQAFVKETLRLHPPTPLL 356

Query: 1104 LPHRAVETCQVMGYTIPQDYQVLVNAYAIGRDPESWKDPSEFRPERFLESNVDYNGNHFE 1283
            LP RA+ETC VM YTIP++ Q++VNA+AIGRDP++W DP  F+PERFL S+VDY GN FE
Sbjct: 357  LPRRALETCTVMNYTIPKECQIMVNAWAIGRDPKTWDDPLNFKPERFLSSDVDYKGNDFE 416

Query: 1284 FIPFGSGRRICIGMPLATRTVPLIVSSLVHNFYWSLPDGKSPEELEMNEILSLSLAIDPS 1463
             IPFG GRRIC G+PLA++ + LIV++LV NF WSLP G S  EL M+E   L+L  DP 
Sbjct: 417  LIPFGGGRRICPGLPLASQFISLIVATLVQNFEWSLPQGMSTSELSMDEKFGLTLQKDPP 476

Query: 1464 LSIIPKVR 1487
            L I+ K R
Sbjct: 477  LLIVLKAR 484


>emb|CBI31830.3| unnamed protein product [Vitis vinifera]
          Length = 1538

 Score =  464 bits (1193), Expect = e-128
 Identities = 243/501 (48%), Positives = 343/501 (68%), Gaps = 13/501 (2%)
 Frame = +3

Query: 24   NTQMEEVIT--LSLLSFI------PFVIVLYLLFKPKHNLPPSPRPSWPLIGNIPAILGS 179
            NT   + +T  +SL SF+      PF+++L  +F     LPP P P WP+IGN+  +   
Sbjct: 1044 NTMDSDTVTADISLSSFVYALLLLPFLLILKHIFLKPPPLPPGPYP-WPIIGNLLQL--G 1100

Query: 180  KTPLHVTLTDLAQVHGPLMVVTLGTAPTVVASTREAAMEILKTHDRALSGRHIAKSFRIK 359
            K P HV L  LA++HGPLM + LGT   VVAS+  AA+E+LKTHDR LSGR+++ S  +K
Sbjct: 1101 KNP-HVKLASLAKLHGPLMSLRLGTQLMVVASSPAAALEVLKTHDRTLSGRYVSSSLSVK 1159

Query: 360  E--MNKHSLVWSN-CTDTWKLLRKLARTEIFSPRMLQIQEPVRENKVGELVEFLRGREGK 530
            +  +N  SL ++  CT+ WK LR + RTE+FS + ++    +RE KV ELVEFL  +EG+
Sbjct: 1160 DPKLNHLSLAFAKECTNNWKNLRTICRTEMFSGKAMESHVELRERKVMELVEFLATKEGE 1219

Query: 531  VVKISQFVFGTLLNIIGNVVFSKDVFLFDDDKIGMQSLIKELLMIGASPNLAEFYPILEV 710
            VVK+   VF T+ NI+ N  FS D  L D ++ G++  I     +GA+PNL++FYPIL+ 
Sbjct: 1220 VVKVMDLVFTTICNILSNTFFSMD--LCDFEREGLKDFIYRAAELGATPNLSDFYPILDG 1277

Query: 711  LDLQGLRRRCADRVSKVNKLWESTVKERRLGRSGDA--KDMLDVLLDNGFSDVQINVLFL 884
            L+L G +++  + + ++   WE T+KERR  ++  +  +D+L+  L+  F D QIN + L
Sbjct: 1278 LNLHGSKKKSKEALGRILATWEGTLKERRKQKNPGSSHRDLLEAFLEIRFEDDQINQVIL 1337

Query: 885  ETFGPGSETSSATIEWVMAELIKNPDKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQACV 1064
            E F  G++TS+ TIEW + +LI+NPD + KLR EL +++G  S V+E+H+P LPYLQACV
Sbjct: 1338 ELFSAGADTSTLTIEWAITQLIRNPDVMYKLRDELTKIIGE-SPVRESHLPHLPYLQACV 1396

Query: 1065 KETMRLHPAAPFLLPHRAVETCQVMGYTIPQDYQVLVNAYAIGRDPESWKDPSEFRPERF 1244
            KET+RLHP AP LLPHRA+ETCQVMGYTIP+D QV VN +A+GRDP+ W DP  F PERF
Sbjct: 1397 KETLRLHPPAPLLLPHRAMETCQVMGYTIPKDSQVFVNIWAMGRDPKVWDDPLSFTPERF 1456

Query: 1245 LESNVDYNGNHFEFIPFGSGRRICIGMPLATRTVPLIVSSLVHNFYWSLPDGKSPEELEM 1424
            L+S +++ GN FE+IPFG+GRRIC GM L  R VPL++++LVH F WSLPD     +++M
Sbjct: 1457 LDSKLEFKGNDFEYIPFGAGRRICPGMALGARQVPLVLATLVHLFDWSLPDNMDSAQIDM 1516

Query: 1425 NEILSLSLAIDPSLSIIPKVR 1487
             E L ++L  +  L ++PKVR
Sbjct: 1517 EEWLVITLRKENPLRLVPKVR 1537



 Score =  462 bits (1190), Expect = e-127
 Identities = 247/504 (49%), Positives = 342/504 (67%), Gaps = 16/504 (3%)
 Frame = +3

Query: 24   NTQMEEVIT--LSLLSFI------PFVIVLYLLFKPKHNLPPSPRPSWPLIGNIPAILGS 179
            NT   + +T  +S+ SF+      PF+++L  +F     LPP P P WP+IGN+  +   
Sbjct: 539  NTMDPDTVTADISIFSFLYALLLLPFLVILKHIFLKPPPLPPGPYP-WPIIGNLLQM--G 595

Query: 180  KTPLHVTLTDLAQVHGPLMVVTLGTAPTVVASTREAAMEILKTHDRALSGRHIAKSFRIK 359
            K P H  L +LA++HGPLM + LGT   VVAS+  AAME+LKTHDRALSGR+++ S  +K
Sbjct: 596  KNP-HAKLANLAKLHGPLMSLRLGTQLMVVASSPAAAMEVLKTHDRALSGRYLSSSVPVK 654

Query: 360  --EMNKHSLVWS-NCTDTWKLLRKLARTEIFSPRMLQIQEPVRENKVGELVEFLRGREGK 530
              ++N  S+V++ +C   WK LR + R E+FS + ++ Q  +RE KV ELVEFL  +EG+
Sbjct: 655  NPKLNHLSIVFAKDCNTNWKNLRAICRMELFSGKAMESQVELRERKVTELVEFLATKEGE 714

Query: 531  VVKISQFVFGTLLNIIGNVVFSKDVFLFDDD-KIG--MQSLIKELLMIGASPNLAEFYPI 701
            VVK+   VF T+ NI+ N  FS D+  F+D+ ++G  ++ LI +    GA+PNL+++YPI
Sbjct: 715  VVKVMDLVFTTICNILSNKFFSMDLCDFEDEGRVGGALKDLIHKNAEFGATPNLSDYYPI 774

Query: 702  LEVLDLQGLRRRCADRVSKVNKLWESTVKERRLGRSGDA--KDMLDVLLDNGFSDVQINV 875
            L  LD+QG+ R+  +   ++   WE  +KERR  RS  +  +D L+ LL+ GF D QIN 
Sbjct: 775  LGGLDIQGINRKAKEMFERIPTTWEDILKERRTQRSNRSSHRDFLEALLEIGFEDDQINQ 834

Query: 876  LFLETFGPGSETSSATIEWVMAELIKNPDKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQ 1055
            + LE F  G+ETSS T+EW MAELI+N D + KLR EL Q+VG  S V+E+H+P LPYLQ
Sbjct: 835  VILELFSAGAETSSLTVEWAMAELIRNQDAMDKLRGELRQIVGE-SPVRESHLPRLPYLQ 893

Query: 1056 ACVKETMRLHPAAPFLLPHRAVETCQVMGYTIPQDYQVLVNAYAIGRDPESWKDPSEFRP 1235
            ACVKE +RLHP AP LLPH A ETCQVMGYTIP+D Q+ VN +A+ RDP+ W DP  F+P
Sbjct: 894  ACVKEALRLHPPAPLLLPHLAAETCQVMGYTIPKDSQIFVNIWAMARDPKIWDDPLSFKP 953

Query: 1236 ERFLESNVDYNGNHFEFIPFGSGRRICIGMPLATRTVPLIVSSLVHNFYWSLPDGKSPEE 1415
            ERFL+S +D+ GN FE+IPFG+GRRIC G+ L  R VPLI+++ VH F WSLP      +
Sbjct: 954  ERFLDSKLDFKGNDFEYIPFGAGRRICPGLALGGRQVPLILATFVHLFGWSLPGNMDSAQ 1013

Query: 1416 LEMNEILSLSLAIDPSLSIIPKVR 1487
            L+M E L ++L  +  L ++P+VR
Sbjct: 1014 LDMEEWLVITLRKEQPLRLVPRVR 1037



 Score =  425 bits (1092), Expect = e-116
 Identities = 226/494 (45%), Positives = 323/494 (65%), Gaps = 14/494 (2%)
 Frame = +3

Query: 42   VITLSLLSFI------PFVIVLYLLFKPKHNLPPSPRPSWPLIGNIPAILGSKTPLHVTL 203
            +  +SL SF+      PF+++   +F     LPP P P WP+IGN+  + G+   LHV L
Sbjct: 7    IADISLFSFLYPLLLLPFLLIFKHIFLKSPPLPPGPYP-WPIIGNLLQMGGN---LHVKL 62

Query: 204  TDLAQVHGPLMVVTLGTAPTVVASTREAAMEILKTHDRALSGRHIAKSFRIK--EMNKHS 377
             +LA+ HGPLM + LGT   VVAS+  AAME+LKTHDR LSGR+++ +  +   ++N  +
Sbjct: 63   ANLAKRHGPLMSLRLGTQIMVVASSSAAAMEVLKTHDRTLSGRYVSTTIPVNSPKLNHLA 122

Query: 378  LVWSN-CTDTWKLLRKLARTEIFSPRMLQIQEPVRENKVGELVEFLRGREGKVVKISQFV 554
            + ++  C   W+ L+ + R E+FS + ++ +  +RE KV ELVEFL  +EG+VVK+   V
Sbjct: 123  MAFAKVCNSDWRNLKAICRMELFSGKAMESRVELRERKVMELVEFLEKKEGEVVKVMDLV 182

Query: 555  FGTLLNIIGNVVFSKDVFLFDDDKIG---MQSLIKELLMIGASPNLAEFYPILEVLDLQG 725
            + T+ NI+ N  FS D   F+   +    ++ L+ E   +GA+ N+ +FYPIL  LD+QG
Sbjct: 183  YTTVCNILSNKFFSIDFSDFEGRDVRGVLLKDLLNENAELGAT-NILDFYPILGGLDIQG 241

Query: 726  LRRRCADRVSKVNKLWESTVKERRLGRSGDAK--DMLDVLLDNGFSDVQINVLFLETFGP 899
            +R++  +   ++   WE  +KERR  R   +   D LD LL+ GF D QIN + +E F  
Sbjct: 242  IRKKLKEIFRRIPTTWEDILKERRKQRIHGSSHGDFLDALLETGFEDDQINHVIMELFFA 301

Query: 900  GSETSSATIEWVMAELIKNPDKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQACVKETMR 1079
            G ETSS T+EW MAELIKN D + KL  EL Q++G  S V+E+H+P LPYLQACVKET+R
Sbjct: 302  GPETSSLTVEWAMAELIKNQDAMHKLCNELTQIIGE-SPVRESHLPHLPYLQACVKETLR 360

Query: 1080 LHPAAPFLLPHRAVETCQVMGYTIPQDYQVLVNAYAIGRDPESWKDPSEFRPERFLESNV 1259
            LHP  P LLPHRA ETCQ+MGYTIP+D  + VN +A+GRDP +W+DP  F+PERFL+S +
Sbjct: 361  LHPTGPLLLPHRATETCQIMGYTIPKDSIIFVNMWAMGRDPGTWEDPLSFKPERFLDSKL 420

Query: 1260 DYNGNHFEFIPFGSGRRICIGMPLATRTVPLIVSSLVHNFYWSLPDGKSPEELEMNEILS 1439
            ++ GN FE+IPFG+GRR+C GMPLA R VP+I+++ V  F WS P      E++M E   
Sbjct: 421  EFKGNDFEYIPFGAGRRMCPGMPLAARLVPMILATFVRLFDWSTPGDMDFAEIDMEERFV 480

Query: 1440 LSLAIDPSLSIIPK 1481
            ++L  +  L ++ K
Sbjct: 481  ITLRKEQPLRLLKK 494


>gb|ACO90224.1| putative (S)-N-methylcoclaurine 3'-hydroxylase [Papaver bracteatum]
          Length = 486

 Score =  462 bits (1189), Expect = e-127
 Identities = 239/490 (48%), Positives = 336/490 (68%), Gaps = 9/490 (1%)
 Frame = +3

Query: 45   ITLSLLSFIPFVIVLYLLFK---PKHNLPPSPRPSWPLIGNIPAILGSKTPLHVTLTDLA 215
            +T+SL++ +     LYL+F+   PK  LPP P+P WP++GN+   LG K   H    +LA
Sbjct: 3    VTVSLVAVV-ITTFLYLIFRDSSPK-GLPPGPKP-WPIVGNLLQ-LGEKP--HSQFAELA 56

Query: 216  QVHGPLMVVTLGTAPTVVASTREAAMEILKTHDRALSGRHIAKSFRIKEMNKHSLVWSNC 395
            + +G L  + LG+   VVAST  AA EILKTHDR LSGR++ +SFR+KE  ++S+VWS C
Sbjct: 57   KTYGDLFTLKLGSETVVVASTPLAASEILKTHDRVLSGRYVFQSFRVKEHVENSIVWSEC 116

Query: 396  TDTWKLLRKLARTEIFSPRMLQIQEPVRENKVGELVEFLRGREGKVVKISQFVFGTLLNI 575
             +TWK LRK+ R E+F+ +M++ Q  +RE+K  E+VEFL+  +G  VKI + VFGTL+NI
Sbjct: 117  NETWKKLRKVCRAELFTQKMIESQAEIRESKAMEMVEFLKRNQGSEVKIVEVVFGTLVNI 176

Query: 576  IGNVVFSKDVFLFDDDKIG---MQSLIKELLMIGASPNLAEFYPILEVLDLQGLRRRCAD 746
             GN++FS+++F   D+  G   M+  +  +L +G S N A+++P L   DL G R+  AD
Sbjct: 177  FGNLIFSQNIFKLGDESSGSVEMKEHLWRMLELGNSTNPADYFPFLGRFDLFGQRKDVAD 236

Query: 747  RVSKVNKLWESTVKERRLGR---SGDAKDMLDVLLDNGFSDVQINVLFLETFGPGSETSS 917
             +  +  +W + +KER++ +   +    D +++LLD+G  D QIN L +E FG G+ETS+
Sbjct: 237  CLQGIYSVWGAMLKERKIAKLHNNSKKNDFVEILLDSGLDDQQINALLMEIFGAGTETSA 296

Query: 918  ATIEWVMAELIKNPDKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQACVKETMRLHPAAP 1097
            +TIEW ++EL KNP+  A +R EL  VVG    VKE+ IP +PYLQA VKET+RLHPA P
Sbjct: 297  STIEWALSELTKNPEVTANMRSELLSVVGKRP-VKESDIPNMPYLQAFVKETLRLHPATP 355

Query: 1098 FLLPHRAVETCQVMGYTIPQDYQVLVNAYAIGRDPESWKDPSEFRPERFLESNVDYNGNH 1277
             LLP RA+ETC+V+ YTIP++ Q++VNA+ IGRDP+ W DP +F PERFL S++D+ GN 
Sbjct: 356  LLLPRRALETCKVLNYTIPKECQIMVNAWGIGRDPKRWTDPLKFAPERFLNSSIDFKGND 415

Query: 1278 FEFIPFGSGRRICIGMPLATRTVPLIVSSLVHNFYWSLPDGKSPEELEMNEILSLSLAID 1457
            FE IPFG+GRRIC G+PLAT+ + LIV +LV NF W LP G  P +L M E   L+L  +
Sbjct: 416  FELIPFGAGRRICPGVPLATQFISLIVPTLVQNFDWGLPKGMDPSQLIMEEKFGLTLQKE 475

Query: 1458 PSLSIIPKVR 1487
            P L I+PK R
Sbjct: 476  PPLYIVPKNR 485


>ref|XP_002274562.1| PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
            [Vitis vinifera]
          Length = 498

 Score =  462 bits (1188), Expect = e-127
 Identities = 243/487 (49%), Positives = 334/487 (68%), Gaps = 8/487 (1%)
 Frame = +3

Query: 51   LSLLSFIPFVIVLYLLFKPKHNLPPSPRPSWPLIGNIPAILGSKTPLHVTLTDLAQVHGP 230
            L  L  +PF+++L  +F     LPP P P WP+IGN+  +   K P H  L +LA++HGP
Sbjct: 16   LYALLLLPFLVILKHIFLKPPPLPPGPYP-WPIIGNLLQM--GKNP-HAKLANLAKLHGP 71

Query: 231  LMVVTLGTAPTVVASTREAAMEILKTHDRALSGRHIAKSFRIK--EMNKHSLVWS-NCTD 401
            LM + LGT   VVAS+  AAME+LKTHDRALSGR+++ S  +K  ++N  S+V++ +C  
Sbjct: 72   LMSLRLGTQLMVVASSPAAAMEVLKTHDRALSGRYLSSSVPVKNPKLNHLSIVFAKDCNT 131

Query: 402  TWKLLRKLARTEIFSPRMLQIQEPVRENKVGELVEFLRGREGKVVKISQFVFGTLLNIIG 581
             WK LR + R E+FS + ++ Q  +RE KV ELVEFL  +EG+VVK+   VF T+ NI+ 
Sbjct: 132  NWKNLRAICRMELFSGKAMESQVELRERKVTELVEFLATKEGEVVKVMDLVFTTICNILS 191

Query: 582  NVVFSKDVFLFDDD-KIG--MQSLIKELLMIGASPNLAEFYPILEVLDLQGLRRRCADRV 752
            N  FS D+  F+D+ ++G  ++ LI +    GA+PNL+++YPIL  LD+QG+ R+  +  
Sbjct: 192  NKFFSMDLCDFEDEGRVGGALKDLIHKNAEFGATPNLSDYYPILGGLDIQGINRKAKEMF 251

Query: 753  SKVNKLWESTVKERRLGRSGDA--KDMLDVLLDNGFSDVQINVLFLETFGPGSETSSATI 926
             ++   WE  +KERR  RS  +  +D L+ LL+ GF D QIN + LE F  G+ETSS T+
Sbjct: 252  ERIPTTWEDILKERRTQRSNRSSHRDFLEALLEIGFEDDQINQVILELFSAGAETSSLTV 311

Query: 927  EWVMAELIKNPDKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQACVKETMRLHPAAPFLL 1106
            EW MAELI+N D + KLR EL Q+VG  S V+E+H+P LPYLQACVKE +RLHP AP LL
Sbjct: 312  EWAMAELIRNQDAMDKLRGELRQIVGE-SPVRESHLPRLPYLQACVKEALRLHPPAPLLL 370

Query: 1107 PHRAVETCQVMGYTIPQDYQVLVNAYAIGRDPESWKDPSEFRPERFLESNVDYNGNHFEF 1286
            PH A ETCQVMGYTIP+D Q+ VN +A+ RDP+ W DP  F+PERFL+S +D+ GN FE+
Sbjct: 371  PHLAAETCQVMGYTIPKDSQIFVNIWAMARDPKIWDDPLSFKPERFLDSKLDFKGNDFEY 430

Query: 1287 IPFGSGRRICIGMPLATRTVPLIVSSLVHNFYWSLPDGKSPEELEMNEILSLSLAIDPSL 1466
            IPFG+GRRIC G+ L  R VPLI+++ VH F WSLP      +L+M E L ++L  +  L
Sbjct: 431  IPFGAGRRICPGLALGGRQVPLILATFVHLFGWSLPGNMDSAQLDMEEWLVITLRKEQPL 490

Query: 1467 SIIPKVR 1487
             ++P+VR
Sbjct: 491  RLVPRVR 497


>gb|AAF05621.1|AF191772_1 (S)-N-methylcoclaurine 3'-hydroxylase [Papaver somniferum]
          Length = 481

 Score =  461 bits (1187), Expect = e-127
 Identities = 238/476 (50%), Positives = 327/476 (68%), Gaps = 9/476 (1%)
 Frame = +3

Query: 87   LYLLFK---PKHNLPPSPRPSWPLIGNIPAILGSKTPLHVTLTDLAQVHGPLMVVTLGTA 257
            LYL+F+   PK  LPP P+P WP++GN+   LG K   H     LA+ +G L  + LG+ 
Sbjct: 11   LYLIFRDSSPK-GLPPGPKP-WPIVGNLLQ-LGEKP--HSQFAQLAETYGDLFSLKLGSE 65

Query: 258  PTVVASTREAAMEILKTHDRALSGRHIAKSFRIKEMNKHSLVWSNCTDTWKLLRKLARTE 437
              VVAST  AA EILKTHDR LSGR++ +SFR+KE  ++S+VWS C +TWK LRK+ RTE
Sbjct: 66   TVVVASTPLAASEILKTHDRVLSGRYVFQSFRVKEHVENSIVWSECNETWKKLRKVCRTE 125

Query: 438  IFSPRMLQIQEPVRENKVGELVEFLRGREGKVVKISQFVFGTLLNIIGNVVFSKDVFLFD 617
            +F+ +M++ Q  VRE+K  E+VE+L+   G  VKI++ VFGTL+NI GN++FS+++F   
Sbjct: 126  LFTQKMIESQAEVRESKAMEMVEYLKKNVGNEVKIAEVVFGTLVNIFGNLIFSQNIFKLG 185

Query: 618  DDKIG---MQSLIKELLMIGASPNLAEFYPILEVLDLQGLRRRCADRVSKVNKLWESTVK 788
            D+  G   M+  +  +L +G S N A+++P L   DL G  +  AD +  +  +W + +K
Sbjct: 186  DESSGSVEMKEHLWRMLELGNSTNPADYFPFLGKFDLFGQSKDVADCLQGIYSVWGAMLK 245

Query: 789  ERRLGR---SGDAKDMLDVLLDNGFSDVQINVLFLETFGPGSETSSATIEWVMAELIKNP 959
            ER++ +   +    D +++LLD+G  D QIN L +E FG G+ETS++TIEW ++EL KNP
Sbjct: 246  ERKIAKQHNNSKKNDFVEILLDSGLDDQQINALLMEIFGAGTETSASTIEWALSELTKNP 305

Query: 960  DKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQACVKETMRLHPAAPFLLPHRAVETCQVM 1139
               A +RLEL  VVG    VKE+ IP +PYLQA VKET+RLHPA P LLP RA+ETC+V+
Sbjct: 306  QVTANMRLELLSVVGKRP-VKESDIPNMPYLQAFVKETLRLHPATPLLLPRRALETCKVL 364

Query: 1140 GYTIPQDYQVLVNAYAIGRDPESWKDPSEFRPERFLESNVDYNGNHFEFIPFGSGRRICI 1319
             YTIP++ Q++VNA+ IGRDP+ W DP +F PERFL S++D+ GN FE IPFG+GRRIC 
Sbjct: 365  NYTIPKECQIMVNAWGIGRDPKRWTDPLKFSPERFLNSSIDFKGNDFELIPFGAGRRICP 424

Query: 1320 GMPLATRTVPLIVSSLVHNFYWSLPDGKSPEELEMNEILSLSLAIDPSLSIIPKVR 1487
            G+PLAT+ + LIVSSLV NF W  P G  P +L M E   L+L  +P L I+PK R
Sbjct: 425  GVPLATQFISLIVSSLVQNFDWGFPKGMDPSQLIMEEKFGLTLQKEPPLYIVPKTR 480


>emb|CAN62647.1| hypothetical protein VITISV_013219 [Vitis vinifera]
          Length = 498

 Score =  461 bits (1187), Expect = e-127
 Identities = 243/487 (49%), Positives = 334/487 (68%), Gaps = 8/487 (1%)
 Frame = +3

Query: 51   LSLLSFIPFVIVLYLLFKPKHNLPPSPRPSWPLIGNIPAILGSKTPLHVTLTDLAQVHGP 230
            L  L  +PF+++L  +F     LPP P P WP+IGN+  +   K P H  L +LA++HGP
Sbjct: 16   LYALLLLPFLVILKHIFLKPPPLPPGPYP-WPIIGNLLQM--GKNP-HAKLANLAKLHGP 71

Query: 231  LMVVTLGTAPTVVASTREAAMEILKTHDRALSGRHIAKSFRIK--EMNKHSLVWS-NCTD 401
            LM + LGT   VVAS+  AAME+LKTHDRALSGR+++ S  +K  ++N  S+V++ +C  
Sbjct: 72   LMSLRLGTQLMVVASSPAAAMEVLKTHDRALSGRYLSXSVPVKNPKLNHLSIVFAKDCNT 131

Query: 402  TWKLLRKLARTEIFSPRMLQIQEPVRENKVGELVEFLRGREGKVVKISQFVFGTLLNIIG 581
             WK LR + R E+FS + ++ Q  +RE KV ELVEFL  +EG+VVK+   VF T+ NI+ 
Sbjct: 132  NWKNLRAICRMELFSGKAMESQVELRERKVTELVEFLATKEGEVVKVMDLVFTTICNILS 191

Query: 582  NVVFSKDVFLFDDD-KIG--MQSLIKELLMIGASPNLAEFYPILEVLDLQGLRRRCADRV 752
            N  FS D+  F+D+ ++G  ++ LI +    GA+PNL+++YPIL  LD+QG+ R+  +  
Sbjct: 192  NKFFSMDLCDFEDEGRVGGALKDLIHKNAEFGATPNLSDYYPILGGLDIQGINRKAKEMF 251

Query: 753  SKVNKLWESTVKERRLGRSGDA--KDMLDVLLDNGFSDVQINVLFLETFGPGSETSSATI 926
             ++   WE  +KERR  RS  +  +D L+ LL+ GF D QIN + LE F  G+ETSS T+
Sbjct: 252  ERIPTTWEDILKERRTQRSNRSSHRDFLEALLEIGFEDDQINQVILELFSAGAETSSLTV 311

Query: 927  EWVMAELIKNPDKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQACVKETMRLHPAAPFLL 1106
            EW MAELI+N D + KLR EL Q+VG  S V+E+H+P LPYLQACVKE +RLHP AP LL
Sbjct: 312  EWAMAELIRNQDAMDKLRGELRQIVGE-SPVRESHLPRLPYLQACVKEALRLHPPAPLLL 370

Query: 1107 PHRAVETCQVMGYTIPQDYQVLVNAYAIGRDPESWKDPSEFRPERFLESNVDYNGNHFEF 1286
            PH A ETCQVMGYTIP+D Q+ VN +A+ RDP+ W DP  F+PERFL+S +D+ GN FE+
Sbjct: 371  PHLAAETCQVMGYTIPKDSQIFVNIWAMARDPKIWDDPLSFKPERFLDSKLDFKGNDFEY 430

Query: 1287 IPFGSGRRICIGMPLATRTVPLIVSSLVHNFYWSLPDGKSPEELEMNEILSLSLAIDPSL 1466
            IPFG+GRRIC G+ L  R VPLI+++ VH F WSLP      +L+M E L ++L  +  L
Sbjct: 431  IPFGAGRRICPGLALGGRQVPLILATFVHLFGWSLPGNMDSAQLDMEEWLVITLRKEQPL 490

Query: 1467 SIIPKVR 1487
             ++P+VR
Sbjct: 491  RLVPRVR 497


>gb|AAF61400.1|AF134590_1 (S)-N-methylcoclaurine 3'-hydroxylase [Papaver somniferum]
          Length = 481

 Score =  459 bits (1182), Expect = e-126
 Identities = 237/476 (49%), Positives = 327/476 (68%), Gaps = 9/476 (1%)
 Frame = +3

Query: 87   LYLLFK---PKHNLPPSPRPSWPLIGNIPAILGSKTPLHVTLTDLAQVHGPLMVVTLGTA 257
            LYL+F+   PK  LPP P+P WP++GN+   LG K   H     LA+ +G L  + LG+ 
Sbjct: 11   LYLIFRDSSPK-GLPPGPKP-WPIVGNLLQ-LGEKP--HSQFAQLAETYGDLFSLKLGSE 65

Query: 258  PTVVASTREAAMEILKTHDRALSGRHIAKSFRIKEMNKHSLVWSNCTDTWKLLRKLARTE 437
              VVAST  AA EILKTHDR LSGR++ +SFR+KE  ++S+VWS C +TWK LRK+ RT+
Sbjct: 66   TVVVASTPLAASEILKTHDRVLSGRYVFQSFRVKEHVENSIVWSECNETWKKLRKVCRTD 125

Query: 438  IFSPRMLQIQEPVRENKVGELVEFLRGREGKVVKISQFVFGTLLNIIGNVVFSKDVFLFD 617
            +F+ +M++ Q  VRE+K  E+VE+L+   G  VKI++ VFGTL+NI GN++FS+++F   
Sbjct: 126  LFTQKMIESQAEVRESKAMEMVEYLKKNVGNEVKIAEVVFGTLVNIFGNLIFSQNIFKLG 185

Query: 618  DDKIG---MQSLIKELLMIGASPNLAEFYPILEVLDLQGLRRRCADRVSKVNKLWESTVK 788
            D+  G   M+  +  +L +G S N A+++P L   DL G  +  AD +  +  +W + +K
Sbjct: 186  DESSGSVEMKEHLWRMLELGNSTNPADYFPFLGKFDLFGQSKDVADCLQGIYSVWGAMLK 245

Query: 789  ERRLGR---SGDAKDMLDVLLDNGFSDVQINVLFLETFGPGSETSSATIEWVMAELIKNP 959
            E ++ +   +    D +++LLD+G  D QIN L +E FG G+ETS++TIEW ++EL KNP
Sbjct: 246  ESKIAKQHNNSKKNDFVEILLDSGLDDQQINALLMEIFGAGTETSASTIEWALSELTKNP 305

Query: 960  DKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQACVKETMRLHPAAPFLLPHRAVETCQVM 1139
               A +RLEL  VVG    VKE+ IP +PYLQA VKET+RLHPA P LLP RA+ETC+V+
Sbjct: 306  QVTANMRLELLSVVGKRP-VKESDIPNMPYLQAFVKETLRLHPATPLLLPRRALETCKVL 364

Query: 1140 GYTIPQDYQVLVNAYAIGRDPESWKDPSEFRPERFLESNVDYNGNHFEFIPFGSGRRICI 1319
             YTIP++ Q++VNA+ IGRDP+ W DP +F PERFL S++D+ GN FE IPFG+GRRIC 
Sbjct: 365  NYTIPKECQIMVNAWGIGRDPKRWTDPLKFSPERFLNSSIDFKGNDFELIPFGAGRRICP 424

Query: 1320 GMPLATRTVPLIVSSLVHNFYWSLPDGKSPEELEMNEILSLSLAIDPSLSIIPKVR 1487
            G+PLAT+ + LIVSSLV NF W LP G  P +L M E   L+L  +P L I+PK R
Sbjct: 425  GVPLATQFISLIVSSLVQNFDWGLPKGMDPSQLIMEEKFGLTLQKEPPLYIVPKTR 480


>ref|XP_002274530.1| PREDICTED: (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2-like
            [Vitis vinifera]
          Length = 515

 Score =  458 bits (1179), Expect = e-126
 Identities = 235/479 (49%), Positives = 332/479 (69%), Gaps = 5/479 (1%)
 Frame = +3

Query: 60   LSFIPFVIVLYLLFKPKHNLPPSPRPSWPLIGNIPAILGSKTPLHVTLTDLAQVHGPLMV 239
            L  +PF+++L  +F     LPP P P WP+IGN+  +   K P HV L  LA++HGPLM 
Sbjct: 19   LLLLPFLLILKHIFLKPPPLPPGPYP-WPIIGNLLQL--GKNP-HVKLASLAKLHGPLMS 74

Query: 240  VTLGTAPTVVASTREAAMEILKTHDRALSGRHIAKSFRIKE--MNKHSLVWSN-CTDTWK 410
            + LGT   VVAS+  AA+E+LKTHDR LSGR+++ S  +K+  +N  SL ++  CT+ WK
Sbjct: 75   LRLGTQLMVVASSPAAALEVLKTHDRTLSGRYVSSSLSVKDPKLNHLSLAFAKECTNNWK 134

Query: 411  LLRKLARTEIFSPRMLQIQEPVRENKVGELVEFLRGREGKVVKISQFVFGTLLNIIGNVV 590
             LR + RTE+FS + ++    +RE KV ELVEFL  +EG+VVK+   VF T+ NI+ N  
Sbjct: 135  NLRTICRTEMFSGKAMESHVELRERKVMELVEFLATKEGEVVKVMDLVFTTICNILSNTF 194

Query: 591  FSKDVFLFDDDKIGMQSLIKELLMIGASPNLAEFYPILEVLDLQGLRRRCADRVSKVNKL 770
            FS D  L D ++ G++  I     +GA+PNL++FYPIL+ L+L G +++  + + ++   
Sbjct: 195  FSMD--LCDFEREGLKDFIYRAAELGATPNLSDFYPILDGLNLHGSKKKSKEALGRILAT 252

Query: 771  WESTVKERRLGRSGDA--KDMLDVLLDNGFSDVQINVLFLETFGPGSETSSATIEWVMAE 944
            WE T+KERR  ++  +  +D+L+  L+  F D QIN + LE F  G++TS+ TIEW + +
Sbjct: 253  WEGTLKERRKQKNPGSSHRDLLEAFLEIRFEDDQINQVILELFSAGADTSTLTIEWAITQ 312

Query: 945  LIKNPDKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQACVKETMRLHPAAPFLLPHRAVE 1124
            LI+NPD + KLR EL +++G  S V+E+H+P LPYLQACVKET+RLHP AP LLPHRA+E
Sbjct: 313  LIRNPDVMYKLRDELTKIIGE-SPVRESHLPHLPYLQACVKETLRLHPPAPLLLPHRAME 371

Query: 1125 TCQVMGYTIPQDYQVLVNAYAIGRDPESWKDPSEFRPERFLESNVDYNGNHFEFIPFGSG 1304
            TCQVMGYTIP+D QV VN +A+GRDP+ W DP  F PERFL+S +++ GN FE+IPFG+G
Sbjct: 372  TCQVMGYTIPKDSQVFVNIWAMGRDPKVWDDPLSFTPERFLDSKLEFKGNDFEYIPFGAG 431

Query: 1305 RRICIGMPLATRTVPLIVSSLVHNFYWSLPDGKSPEELEMNEILSLSLAIDPSLSIIPK 1481
            RRIC GM L  R VPL++++LVH F WSLPD     +++M E L ++L  +  L ++PK
Sbjct: 432  RRICPGMALGARQVPLVLATLVHLFDWSLPDNMDSAQIDMEEWLVITLRKENPLRLVPK 490


>ref|XP_004234364.1| PREDICTED: (S)-N-methylcoclaurine 3'-hydroxylase isozyme 1-like
            [Solanum lycopersicum]
          Length = 486

 Score =  454 bits (1169), Expect = e-125
 Identities = 225/482 (46%), Positives = 335/482 (69%), Gaps = 6/482 (1%)
 Frame = +3

Query: 54   SLLSFIPFVIVLYLLFKPKH-NLPPSPRPSWPLIGNIPAILGSKTPLHVTLTDLAQVHGP 230
            S L FIPF ++++    PK  NLPP PRP W L+GN+  I   KTP HV+L   AQ+HGP
Sbjct: 9    SFLIFIPFFLLIFKQLVPKSTNLPPGPRP-WHLLGNLLQI--GKTP-HVSLAKFAQIHGP 64

Query: 231  LMVVTLGTAPTVVASTREAAMEILKTHDRALSGRHIAK--SFRIKEMNKHSLVWSN-CTD 401
            L+ V LGT   VVAS+  +A EILK+ DR LS R + K  ++ +  +++HS+V+S+  ++
Sbjct: 65   LISVKLGTQLVVVASSPASAAEILKSQDRLLSVRSVPKVATYELSVIDQHSIVFSSDLSN 124

Query: 402  TWKLLRKLARTEIFSPRMLQIQEPVRENKVGELVEFLRGREGKVVKISQFVFGTLLNIIG 581
             WK LR   RT +FSP+ ++ Q  +RE KV E++ FLR R+G+ VKIS+ +FGT+LN +G
Sbjct: 125  QWKFLRAFCRTHLFSPKAVESQAALREKKVSEMMNFLRSRKGETVKISEILFGTILNTLG 184

Query: 582  NVVFSKDV--FLFDDDKIGMQSLIKELLMIGASPNLAEFYPILEVLDLQGLRRRCADRVS 755
            N+ FSKD+    ++ +  G++ +I++ + +GA PN++EFYP+ + LDLQGLR++     +
Sbjct: 185  NLFFSKDLCDLDYETNTSGIKHVIRKFVELGAMPNISEFYPLFDALDLQGLRKQTEIYQN 244

Query: 756  KVNKLWESTVKERRLGRSGDAKDMLDVLLDNGFSDVQINVLFLETFGPGSETSSATIEWV 935
            ++  +W   VKE+R   S  + D LD ++DNGFSD+Q+++L +E    GS+T+++TIEW 
Sbjct: 245  RLVNIWSEIVKEKRQAISRSSSDFLDAMIDNGFSDLQVDILLMELISAGSDTTTSTIEWA 304

Query: 936  MAELIKNPDKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQACVKETMRLHPAAPFLLPHR 1115
            MAEL++N   + KL+ EL   +G    + E+++  LPYL ACVKET+R+HP  PFL+P R
Sbjct: 305  MAELLRNKGAMRKLKAELASKLGENDIITESNVSELPYLAACVKETLRIHPPTPFLIPRR 364

Query: 1116 AVETCQVMGYTIPQDYQVLVNAYAIGRDPESWKDPSEFRPERFLESNVDYNGNHFEFIPF 1295
            A ETC++M YTIP++ ++ VNA+AIGRD  +W+D   FRPERFL SNVD+ G  FEFIPF
Sbjct: 365  APETCKIMDYTIPKNSKLFVNAWAIGRDSNTWEDALSFRPERFLNSNVDFRGQDFEFIPF 424

Query: 1296 GSGRRICIGMPLATRTVPLIVSSLVHNFYWSLPDGKSPEELEMNEILSLSLAIDPSLSII 1475
            G+GRRIC G+  A + + LI++SL+H F WSLP+G+ P +++M E   ++L  + SL  +
Sbjct: 425  GAGRRICPGLGFARQEIQLILASLIHYFEWSLPNGEDPMQIDMKEKFGVTLQKEKSLLAV 484

Query: 1476 PK 1481
            PK
Sbjct: 485  PK 486


>ref|XP_006358914.1| PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme
            2-like [Solanum tuberosum]
          Length = 496

 Score =  454 bits (1167), Expect = e-125
 Identities = 236/497 (47%), Positives = 333/497 (67%), Gaps = 11/497 (2%)
 Frame = +3

Query: 30   QMEEVITLSLLSFIPFVIVLYLLFKPKHN---LPPSPRPSWPLIGNIPAILGSKTPLHVT 200
            Q  E++ L  L   P +  ++ +FK       LPP P P WP+IGNI  I   K P H+T
Sbjct: 3    QQFEILFLLPLFLFPLIFFIFKIFKKSSKITQLPPGPTP-WPVIGNIFQI--GKMP-HIT 58

Query: 201  LTDLAQVHGPLMVVTLGTAPTVVASTREAAMEILKTHDRALSGRHIAKSFRIK--EMNKH 374
            LT+ A+ +GPL+ + LGT   VV S+   A+EI KTHDR LSGRH+  + R K  ++ K 
Sbjct: 59   LTNFAKTYGPLISLRLGTQCLVVGSSPSVAIEIFKTHDRILSGRHVPNAVRSKGSDLEKT 118

Query: 375  SLVW-SNCTDTWKLLRKLARTEIFSPRMLQIQEPVRENKVGELVEFLRGREGKVVKISQF 551
            SL W S C   W+ LR L RT++F+ ++L+ Q  +RE KV ELVEFLR +EG+VV I + 
Sbjct: 119  SLGWKSECDSGWRYLRTLCRTDLFAGKVLESQACLREKKVMELVEFLRSKEGQVVNIGEL 178

Query: 552  VFGTLLNIIGNVVFSKDVFLFDDDKIG--MQSLIKELLMIGASPNLAEFYPILEVLDLQG 725
            VF T+LN++ NV+ SKD+   +++     ++SL++ ++ +G++PN+++FYPIL  LDLQG
Sbjct: 179  VFATVLNMLSNVLISKDMIHLEEETEDSEIKSLVRGIVEVGSAPNISDFYPILGKLDLQG 238

Query: 726  LRRRCADRVSKVNKLWESTVKERRLGRSGDA---KDMLDVLLDNGFSDVQINVLFLETFG 896
            LR++  D V+K   +WE  ++ERR  R  D+   +D L+ LLDNGF++  IN LF+E   
Sbjct: 239  LRKKSTDLVTKFCSIWEPIIEERRNSRENDSSSQQDFLETLLDNGFTNDHINQLFMELLS 298

Query: 897  PGSETSSATIEWVMAELIKNPDKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQACVKETM 1076
             GS+TS+  IEW MAELIKN + + K++ EL+  +  +  +KE+ +  + Y+QACVKE  
Sbjct: 299  AGSDTSTTAIEWAMAELIKNVETMKKVQEELEIELSESDYLKESQVLQMSYVQACVKEAF 358

Query: 1077 RLHPAAPFLLPHRAVETCQVMGYTIPQDYQVLVNAYAIGRDPESWKDPSEFRPERFLESN 1256
            RLHP AP LLPHRA+ETCQVM YTIP+  Q+LVN +AI RDP  W++P  FRP+RFL S+
Sbjct: 359  RLHPPAPLLLPHRAIETCQVMSYTIPKGAQILVNVWAITRDPFIWEEPDMFRPQRFLSSD 418

Query: 1257 VDYNGNHFEFIPFGSGRRICIGMPLATRTVPLIVSSLVHNFYWSLPDGKSPEELEMNEIL 1436
            +D+ GN FEF+PF +GRR+C GMP+A   VPL+++SLVH F W LP GK   EL+M E  
Sbjct: 419  MDFKGNDFEFLPFSAGRRMCPGMPMAAIQVPLVLASLVHFFDWELPHGKCLIELDMTEKF 478

Query: 1437 SLSLAIDPSLSIIPKVR 1487
             ++L     L +IPK R
Sbjct: 479  GITLQKKEPLLLIPKAR 495


>sp|O64900.1|C80B2_ESCCA RecName: Full=(S)-N-methylcoclaurine 3'-hydroxylase isozyme 2;
            AltName: Full=Cytochrome P450 80B2
            gi|3127029|gb|AAC39453.1| (S)-N-methylcoclaurine
            3'-hydroxylase [Eschscholzia californica]
          Length = 488

 Score =  454 bits (1167), Expect = e-125
 Identities = 235/492 (47%), Positives = 331/492 (67%), Gaps = 9/492 (1%)
 Frame = +3

Query: 39   EVITLSLLSFIPFVIVLYLLFKPK--HNLPPSPRPSWPLIGNIPAILGSKTPLHVTLTDL 212
            EV+T++L++ I    +LYLLF      NLPP P+P WP++GN+   LG K   H    +L
Sbjct: 2    EVVTVALIAVI-ISSILYLLFGSSGHKNLPPGPKP-WPIVGNLLQ-LGEKP--HAQFAEL 56

Query: 213  AQVHGPLMVVTLGTAPTVVASTREAAMEILKTHDRALSGRHIAKSFRIKEMNKHSLVWSN 392
            AQ +G +  + +GT   VVAST  AA EILKTHDR LS R++ +SFR+K   ++S+VWS+
Sbjct: 57   AQTYGDIFTLKMGTETVVVASTSSAASEILKTHDRILSARYVFQSFRVKGHVENSIVWSD 116

Query: 393  CTDTWKLLRKLARTEIFSPRMLQIQEPVRENKVGELVEFLRGREGKVVKISQFVFGTLLN 572
            CT+TWK LRK+ RTE+F+ +M++ Q  VRE K  E+VE+L  ++G+ VKI + +FGTL+N
Sbjct: 117  CTETWKNLRKVCRTELFTQKMIESQAHVREKKCEEMVEYLMKKQGEEVKIVEVIFGTLVN 176

Query: 573  IIGNVVFSKDVFLFDDDKIG---MQSLIKELLMIGASPNLAEFYPILEVLDLQGLRRRCA 743
            I GN++FS+++F       G    +  +  +L +G S N A+++P+L   DL G R+  A
Sbjct: 177  IFGNLIFSQNIFELGXPNSGSSEFKEYLWRMLELGNSTNPADYFPMLGKFDLFGQRKEVA 236

Query: 744  DRVSKVNKLWESTVKERRLGRSGDA----KDMLDVLLDNGFSDVQINVLFLETFGPGSET 911
            + +  +  +W + ++ER+L +  D      D +DV LD+G +D QIN L +E FG G+ET
Sbjct: 237  ECLKGIYAIWGAMLQERKLAKKVDGYQSKNDFVDVCLDSGLNDYQINALLMELFGAGTET 296

Query: 912  SSATIEWVMAELIKNPDKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQACVKETMRLHPA 1091
            S++TIEW M EL KNP   AKLR EL  VVG  S VKE+  P LPYL+A VKET+RLHP 
Sbjct: 297  SASTIEWAMTELTKNPKITAKLRSELQTVVGERS-VKESDFPNLPYLEATVKETLRLHPP 355

Query: 1092 APFLLPHRAVETCQVMGYTIPQDYQVLVNAYAIGRDPESWKDPSEFRPERFLESNVDYNG 1271
             P LLP RA+ETC ++ YTIP+D Q++VNA+ IGRDP++W DP  F PERFL S+VD+ G
Sbjct: 356  TPLLLPRRALETCTILNYTIPKDCQIMVNAWGIGRDPKTWIDPLTFSPERFLNSSVDFRG 415

Query: 1272 NHFEFIPFGSGRRICIGMPLATRTVPLIVSSLVHNFYWSLPDGKSPEELEMNEILSLSLA 1451
            N F  IPFG+GRRIC G+P+A + + L+V++ V N  W LP+G S + L + E   L+L 
Sbjct: 416  NDFSLIPFGAGRRICPGLPIANQFIALLVATFVQNLDWCLPNGMSVDHLIVEEKFGLTLQ 475

Query: 1452 IDPSLSIIPKVR 1487
             +P L I+PK R
Sbjct: 476  KEPPLFIVPKSR 487


>ref|XP_006358870.1| PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme
            2-like [Solanum tuberosum]
          Length = 495

 Score =  452 bits (1163), Expect = e-124
 Identities = 237/493 (48%), Positives = 336/493 (68%), Gaps = 10/493 (2%)
 Frame = +3

Query: 39   EVITLSLLSFIPFVIVLYLLFKPKH--NLPPSPRPSWPLIGNIPAILGSKTPLHVTLTDL 212
            E++ L     +P    L+ +F+      LPP P P WP+IGNI  +   K P H+TLT+ 
Sbjct: 6    EILFLLPFFLLPLTFFLFKVFRSSKITQLPPGPTP-WPVIGNIFHM--GKMP-HITLTNF 61

Query: 213  AQVHGPLMVVTLGTAPTVVASTREAAMEILKTHDRALSGRHIAKSFRIK--EMNKHSLVW 386
            A+++GPLM + LGT   VV S+  AA+EILKTHDR LSGRH+  +   K  +++K S+ W
Sbjct: 62   AKIYGPLMSLRLGTQCLVVGSSSSAAIEILKTHDRILSGRHVPNAMPAKRSDLDKISMGW 121

Query: 387  -SNCTDTWKLLRKLARTEIFSPRMLQIQEPVRENKVGELVEFLRGREGKVVKISQFVFGT 563
             S C + W+ LR L +TE+FS ++L+ Q  +RE KV ELVEFLR +EG+VV I + VF T
Sbjct: 122  NSECHNEWRCLRTLCKTELFSGKVLESQAYLREKKVMELVEFLRSKEGQVVNIGELVFAT 181

Query: 564  LLNIIGNVVFSKDVFLFDDDKI--GMQSLIKELLMIGASPNLAEFYPILEVLDLQGLRRR 737
            +LN++ NV+ SKD+   + +    G+++LI+ L+   ++PNL++FYP+L  LDLQGLR+R
Sbjct: 182  VLNMLSNVLISKDMVNLEKETEDGGIRNLIRGLVEAVSAPNLSDFYPVLGKLDLQGLRKR 241

Query: 738  CADRVSKVNKLWESTVKERRLGR---SGDAKDMLDVLLDNGFSDVQINVLFLETFGPGSE 908
                ++K+   WE  ++ERR  +   S   +D L+ LLDNG ++  I+ LF+E    GS+
Sbjct: 242  ARYVMTKIRSNWEPILEERRKNKVSGSSSQQDFLEALLDNGLTNDCIHQLFVELVAAGSD 301

Query: 909  TSSATIEWVMAELIKNPDKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQACVKETMRLHP 1088
            TS++TIEW MAELIKN + + K++ EL+  +  +    E+ +  + Y+QAC+KET+RLHP
Sbjct: 302  TSTSTIEWAMAELIKNVESMKKVQEELEIELSESDYPNESQLLQMSYVQACMKETLRLHP 361

Query: 1089 AAPFLLPHRAVETCQVMGYTIPQDYQVLVNAYAIGRDPESWKDPSEFRPERFLESNVDYN 1268
             APFLLPHRA+ETCQVM YTIP+D Q+LVN +AI RDP  W+DP  FRP+RFL S++D+ 
Sbjct: 362  PAPFLLPHRAIETCQVMSYTIPKDAQILVNVWAITRDPLIWEDPEMFRPQRFLSSDMDFK 421

Query: 1269 GNHFEFIPFGSGRRICIGMPLATRTVPLIVSSLVHNFYWSLPDGKSPEELEMNEILSLSL 1448
            GN FEF+PFG+GRRIC G+P+A   VPL+++SLVH F W LP GK P EL+M E   ++L
Sbjct: 422  GNDFEFLPFGAGRRICPGLPMAAIKVPLVLASLVHFFDWELPHGKRPTELDMTEKFGVTL 481

Query: 1449 AIDPSLSIIPKVR 1487
                 L +IPK R
Sbjct: 482  QKKEPLLLIPKAR 494


>sp|O64899.1|C80B1_ESCCA RecName: Full=(S)-N-methylcoclaurine 3'-hydroxylase isozyme 1;
            AltName: Full=Cytochrome P450 80B1
            gi|3127027|gb|AAC39452.1| (S)-N-methylcoclaurine
            3'-hydroxylase [Eschscholzia californica]
          Length = 487

 Score =  451 bits (1160), Expect = e-124
 Identities = 232/489 (47%), Positives = 328/489 (67%), Gaps = 11/489 (2%)
 Frame = +3

Query: 54   SLLSFIPFVI--VLYLLF--KPKHNLPPSPRPSWPLIGNIPAILGSKTPLHVTLTDLAQV 221
            S ++ I  +I  +LYLLF      NLPP P+P WP++GN+   LG K   H    +LAQ 
Sbjct: 3    STVALIAVIISSILYLLFGGSGHKNLPPGPKP-WPIVGNLLQ-LGEKP--HAQFAELAQT 58

Query: 222  HGPLMVVTLGTAPTVVASTREAAMEILKTHDRALSGRHIAKSFRIKEMNKHSLVWSNCTD 401
            +G +  + +GT   VVAST  AA EILKTHDR LS R++ +SFR+K   ++S+VWS+CT+
Sbjct: 59   YGDIFTLKMGTETVVVASTSSAASEILKTHDRILSARYVFQSFRVKGHVENSIVWSDCTE 118

Query: 402  TWKLLRKLARTEIFSPRMLQIQEPVRENKVGELVEFLRGREGKVVKISQFVFGTLLNIIG 581
            TWK LRK+ RTE+F+ +M++ Q  VRE K  E+VE+L  ++G+ VKI + +FGTL+NI G
Sbjct: 119  TWKNLRKVCRTELFTQKMIESQAHVREKKCEEMVEYLMKKQGEEVKIVEVIFGTLVNIFG 178

Query: 582  NVVFSKDVFLFDDDKIG---MQSLIKELLMIGASPNLAEFYPILEVLDLQGLRRRCADRV 752
            N++FS+++F   D   G    +  +  +L +G S N A+++P+L   DL G R+  A+ +
Sbjct: 179  NLIFSQNIFELGDPNSGSSEFKEYLWRMLELGNSTNPADYFPMLGKFDLFGQRKEVAECL 238

Query: 753  SKVNKLWESTVKERRLGRSGDA----KDMLDVLLDNGFSDVQINVLFLETFGPGSETSSA 920
              +  +W + ++ER+L +  D      D +DV LD+G +D QIN L +E FG G+ETS++
Sbjct: 239  KGIYAIWGAMLQERKLAKKVDGYKSKNDFVDVCLDSGLNDYQINALLMELFGAGTETSAS 298

Query: 921  TIEWVMAELIKNPDKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQACVKETMRLHPAAPF 1100
            TIEW M EL KNP   AK+R E+  VVG  S VKE+  P LPYL+A VKET+RLHP  P 
Sbjct: 299  TIEWAMTELTKNPKITAKIRSEIQTVVGERS-VKESDFPNLPYLEATVKETLRLHPPTPL 357

Query: 1101 LLPHRAVETCQVMGYTIPQDYQVLVNAYAIGRDPESWKDPSEFRPERFLESNVDYNGNHF 1280
            LLP RA+ETC ++ YTIP+D Q++VNA+ IGRDP++W DP  F PERFL S+VD+ GN F
Sbjct: 358  LLPRRALETCTILNYTIPKDCQIMVNAWGIGRDPKTWTDPLTFSPERFLNSSVDFRGNDF 417

Query: 1281 EFIPFGSGRRICIGMPLATRTVPLIVSSLVHNFYWSLPDGKSPEELEMNEILSLSLAIDP 1460
              IPFG+GRRIC G+P+A + + L+V++ V N  W LP+G S + L + E   L+L  +P
Sbjct: 418  SLIPFGAGRRICPGLPIANQFIALLVATFVQNLDWCLPNGMSVDHLIVEEKFGLTLQKEP 477

Query: 1461 SLSIIPKVR 1487
             L I+PK R
Sbjct: 478  PLFIVPKSR 486


>ref|XP_006353352.1| PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme
            2-like [Solanum tuberosum]
          Length = 486

 Score =  450 bits (1157), Expect = e-123
 Identities = 222/481 (46%), Positives = 337/481 (70%), Gaps = 6/481 (1%)
 Frame = +3

Query: 54   SLLSFIPFVIVLYLLFKPKH-NLPPSPRPSWPLIGNIPAILGSKTPLHVTLTDLAQVHGP 230
            S L FI F +++     PK  NLPP PRP WPL+GNI  I   K+P H++L   A+++GP
Sbjct: 9    SFLIFIAFFLLILKQLIPKSPNLPPGPRP-WPLLGNILQI--GKSP-HISLAQFAKIYGP 64

Query: 231  LMVVTLGTAPTVVASTREAAMEILKTHDRALSGRHIAK--SFRIKEMNKHSLVWSN-CTD 401
            L+ V LGT   VVAS+ ++A EILKT DR LS R + K  ++ +  +++HS+V+S+  ++
Sbjct: 65   LISVKLGTQLVVVASSPDSAAEILKTQDRLLSVRSVPKVATYELSVIDQHSIVFSSDLSN 124

Query: 402  TWKLLRKLARTEIFSPRMLQIQEPVRENKVGELVEFLRGREGKVVKISQFVFGTLLNIIG 581
             WK LR   RT +FSP+ ++ Q  +RE KV E++ FLR R+G+ VKIS+ +F T+LN +G
Sbjct: 125  HWKFLRAFCRTHLFSPKAVESQAALREKKVSEMIHFLRSRKGETVKISEIMFATILNTLG 184

Query: 582  NVVFSKDV--FLFDDDKIGMQSLIKELLMIGASPNLAEFYPILEVLDLQGLRRRCADRVS 755
            N+ FSKD+    ++ +  G++ +I++ + +GA PN++EFYP+ + LDLQGLR++     +
Sbjct: 185  NLFFSKDLCDLDYETNTSGIKHVIRKFVELGAMPNISEFYPLFDALDLQGLRKQTEIYQN 244

Query: 756  KVNKLWESTVKERRLGRSGDAKDMLDVLLDNGFSDVQINVLFLETFGPGSETSSATIEWV 935
            ++  +W   VKE+R   S  + D LDV++D+GFSD+Q+++L +E    GS+T+++TIEW 
Sbjct: 245  QLFNIWSDIVKEKRQAISRSSSDFLDVMIDSGFSDLQVDILLMELISAGSDTTTSTIEWA 304

Query: 936  MAELIKNPDKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQACVKETMRLHPAAPFLLPHR 1115
            MAEL++N   + KL+ EL   +G    + E++I  LPYL ACVKET+R+HP  PFL+P R
Sbjct: 305  MAELLRNKGAMHKLQAELTSKIGENDILTESNITELPYLAACVKETLRIHPPTPFLIPRR 364

Query: 1116 AVETCQVMGYTIPQDYQVLVNAYAIGRDPESWKDPSEFRPERFLESNVDYNGNHFEFIPF 1295
            A ETC++M YTIP++ ++ VN +AIGR+  +W+D   FRPERFL+SNVD+ G  FEFIPF
Sbjct: 365  APETCKIMDYTIPKNSRLFVNVWAIGRNSNTWEDALSFRPERFLDSNVDFRGQDFEFIPF 424

Query: 1296 GSGRRICIGMPLATRTVPLIVSSLVHNFYWSLPDGKSPEELEMNEILSLSLAIDPSLSII 1475
            G+GRRIC G+P A + V LI++SL+H+F WSLP+G+ P +++M E   ++L  + SL ++
Sbjct: 425  GAGRRICPGLPFARQEVHLILASLIHHFEWSLPNGEDPMQIDMKEKFGVTLQKEKSLLVV 484

Query: 1476 P 1478
            P
Sbjct: 485  P 485


>emb|CBI34714.3| unnamed protein product [Vitis vinifera]
          Length = 936

 Score =  448 bits (1153), Expect = e-123
 Identities = 236/494 (47%), Positives = 339/494 (68%), Gaps = 13/494 (2%)
 Frame = +3

Query: 45   ITLSLLSFIPFVIVLYL-LFKPKHNL-----PPSPRPSWPLIGNIPAILGSKTPLHVTLT 206
            + L  L  +P ++ L L L K   +L     PP P P WP++GN+   LG+    H++L 
Sbjct: 447  VFLPFLLLLPLLVFLILKLLKDSSSLKSPPLPPGPSP-WPILGNL-LHLGNMP--HISLA 502

Query: 207  DLAQVHGPLMVVTLGTAPTVVASTREAAMEILKTHDRALSGRHIAKSFRIK--EMNKHSL 380
              +Q +GPL+ + LG+   VVAST  AAMEILKTHDR LSGR++  +   K  E+N+ SL
Sbjct: 503  RFSQSYGPLISLRLGSQILVVASTSSAAMEILKTHDRVLSGRYVPHAVPAKNSEINRMSL 562

Query: 381  VWS-NCTDTWKLLRKLARTEIFSPRMLQIQEPVRENKVGELVEFLRGREGKVVKISQFVF 557
             W+  C D WK LR + R E+FS ++++ Q  V E KV E+V F+  +EG+V+K+ + VF
Sbjct: 563  GWAVECNDAWKNLRTVCRAELFSTKVMESQAWVGEKKVMEMVRFVSTKEGEVMKVGEVVF 622

Query: 558  GTLLNIIGNVVFSKDVFLFDDDKI--GMQSLIKELLMIGASPNLAEFYPILEVLDLQGLR 731
             T+LN +  V+ S+D   F+DD    GM+ L+++++M  A+PNL +FY I   LDLQGL 
Sbjct: 623  ATVLNTLTTVLMSRDFISFEDDYKDGGMKGLVRKMMMAMAAPNLDDFYLIFSGLDLQGLN 682

Query: 732  RRCADRVSKVNKLWESTVKERRLGRSGDA--KDMLDVLLDNGFSDVQINVLFLETFGPGS 905
            ++  + ++++  +WES ++ERR G S D   +D L++L+ +G+SD QIN LF+E    G+
Sbjct: 683  KKTKELIARICSMWESVIRERREGASDDPSKQDFLNILIRSGYSDDQINQLFMELLTAGA 742

Query: 906  ETSSATIEWVMAELIKNPDKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQACVKETMRLH 1085
            +TSS+T+EW MAELIK+P+ + K+  EL + +      K + +P LPYLQACVKET+RLH
Sbjct: 743  DTSSSTLEWAMAELIKSPESMKKVHEELAREISDNLP-KASDLPHLPYLQACVKETLRLH 801

Query: 1086 PAAPFLLPHRAVETCQVMGYTIPQDYQVLVNAYAIGRDPESWKDPSEFRPERFLESNVDY 1265
            P+AP LLP RA  +C+VM YTIP+D Q+ VNA+AIGRDP +W+DP  F+PERFL S VD+
Sbjct: 802  PSAPLLLPRRASVSCEVMNYTIPKDSQIWVNAWAIGRDPMNWEDPLVFKPERFLNSAVDF 861

Query: 1266 NGNHFEFIPFGSGRRICIGMPLATRTVPLIVSSLVHNFYWSLPDGKSPEELEMNEILSLS 1445
             GN+ EFIPFG+GRRIC G+P+A R +PLI++SL H F WSLP+G +P+EL+MN+   ++
Sbjct: 862  KGNNLEFIPFGAGRRICPGLPMAARLLPLILASLTHFFDWSLPNGTTPDELDMNDKFGIA 921

Query: 1446 LAIDPSLSIIPKVR 1487
            L  +  L IIPKVR
Sbjct: 922  LQKEQPLLIIPKVR 935


>ref|XP_002283461.1| PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme
            2-like [Vitis vinifera]
          Length = 503

 Score =  448 bits (1153), Expect = e-123
 Identities = 236/494 (47%), Positives = 339/494 (68%), Gaps = 13/494 (2%)
 Frame = +3

Query: 45   ITLSLLSFIPFVIVLYL-LFKPKHNL-----PPSPRPSWPLIGNIPAILGSKTPLHVTLT 206
            + L  L  +P ++ L L L K   +L     PP P P WP++GN+   LG+    H++L 
Sbjct: 14   VFLPFLLLLPLLVFLILKLLKDSSSLKSPPLPPGPSP-WPILGNL-LHLGNMP--HISLA 69

Query: 207  DLAQVHGPLMVVTLGTAPTVVASTREAAMEILKTHDRALSGRHIAKSFRIK--EMNKHSL 380
              +Q +GPL+ + LG+   VVAST  AAMEILKTHDR LSGR++  +   K  E+N+ SL
Sbjct: 70   RFSQSYGPLISLRLGSQILVVASTSSAAMEILKTHDRVLSGRYVPHAVPAKNSEINRMSL 129

Query: 381  VWS-NCTDTWKLLRKLARTEIFSPRMLQIQEPVRENKVGELVEFLRGREGKVVKISQFVF 557
             W+  C D WK LR + R E+FS ++++ Q  V E KV E+V F+  +EG+V+K+ + VF
Sbjct: 130  GWAVECNDAWKNLRTVCRAELFSTKVMESQAWVGEKKVMEMVRFVSTKEGEVMKVGEVVF 189

Query: 558  GTLLNIIGNVVFSKDVFLFDDDKI--GMQSLIKELLMIGASPNLAEFYPILEVLDLQGLR 731
             T+LN +  V+ S+D   F+DD    GM+ L+++++M  A+PNL +FY I   LDLQGL 
Sbjct: 190  ATVLNTLTTVLMSRDFISFEDDYKDGGMKGLVRKMMMAMAAPNLDDFYLIFSGLDLQGLN 249

Query: 732  RRCADRVSKVNKLWESTVKERRLGRSGDA--KDMLDVLLDNGFSDVQINVLFLETFGPGS 905
            ++  + ++++  +WES ++ERR G S D   +D L++L+ +G+SD QIN LF+E    G+
Sbjct: 250  KKTKELIARICSMWESVIRERREGASDDPSKQDFLNILIRSGYSDDQINQLFMELLTAGA 309

Query: 906  ETSSATIEWVMAELIKNPDKLAKLRLELDQVVGPTSQVKEAHIPLLPYLQACVKETMRLH 1085
            +TSS+T+EW MAELIK+P+ + K+  EL + +      K + +P LPYLQACVKET+RLH
Sbjct: 310  DTSSSTLEWAMAELIKSPESMKKVHEELAREISDNLP-KASDLPHLPYLQACVKETLRLH 368

Query: 1086 PAAPFLLPHRAVETCQVMGYTIPQDYQVLVNAYAIGRDPESWKDPSEFRPERFLESNVDY 1265
            P+AP LLP RA  +C+VM YTIP+D Q+ VNA+AIGRDP +W+DP  F+PERFL S VD+
Sbjct: 369  PSAPLLLPRRASVSCEVMNYTIPKDSQIWVNAWAIGRDPMNWEDPLVFKPERFLNSAVDF 428

Query: 1266 NGNHFEFIPFGSGRRICIGMPLATRTVPLIVSSLVHNFYWSLPDGKSPEELEMNEILSLS 1445
             GN+ EFIPFG+GRRIC G+P+A R +PLI++SL H F WSLP+G +P+EL+MN+   ++
Sbjct: 429  KGNNLEFIPFGAGRRICPGLPMAARLLPLILASLTHFFDWSLPNGTTPDELDMNDKFGIA 488

Query: 1446 LAIDPSLSIIPKVR 1487
            L  +  L IIPKVR
Sbjct: 489  LQKEQPLLIIPKVR 502