BLASTX nr result
ID: Cimicifuga21_contig00003300
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Cimicifuga21_contig00003300
(6455 letters)
Database: ./nr
23,641,837 sequences; 8,123,359,852 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|XP_001311646.1| hypothetical protein [Trichomonas vaginalis ... 123 4e-42
tpg|DAA02258.1| TPA_exp: S6 sporozoite-induced protein [Plasmodi... 157 5e-35
ref|XP_725378.1| hypothetical protein [Plasmodium yoelii yoelii ... 157 5e-35
gb|ACJ64146.1| sporozoite-specific transmembrane protein S6 prec... 142 1e-30
gb|AAF15293.3| erythrocyte membrane-associated giant protein ant... 140 4e-30
>ref|XP_001311646.1| hypothetical protein [Trichomonas vaginalis G3]
gi|121893464|gb|EAX98716.1| hypothetical protein
TVAG_480920 [Trichomonas vaginalis G3]
Length = 1996
Score = 123 bits (309), Expect(2) = 4e-42
Identities = 195/923 (21%), Positives = 370/923 (40%), Gaps = 52/923 (5%)
Frame = -1
Query: 3089 EEATDSTQETEIVTLEEETPKNSLNDFRATEAPLEEITKMKKSDKLNYTPTESAMSEEQV 2910
++ + T+ V +E+ P N N + + EE+ K + + ++ E ++
Sbjct: 1122 DDYEEETKHENNVQEQEDEPTNKANPIASVDEEFEEVFKDEDREFEKHSQEELNREVKEE 1181
Query: 2909 IKEIPEKTES----ANHET----IFVTQPTEKLSLHEAEPQGGELVDASDDASVEMFSTP 2754
+ IP+K E+ +NHE I Q ++ ++ E E Q E V D ++
Sbjct: 1182 REFIPQKDETKDQESNHEDFEEEIKEEQKIDEDTIKEEEEQKTEKVQNDFDEEIKEEDIK 1241
Query: 2753 IEEHGASSLDP--------DMEDVKQGEIATLDDNATDNTFTAENAETEHEKPEVPVEN- 2601
E+H + D D E +Q +T++++ T+ + E + E V+N
Sbjct: 1242 -EKHEEVTKDKVEMNEEQNDEEKQQQEVESTIEEDITEQNVEPKKEEQTIQDFEEEVQNY 1300
Query: 2600 ---SAVATQSVDKDTQTTLVSEITASKASSDDLSEEKPQKSSMLISA--KNEFNAVGMKE 2436
++ V ++ + L E + ++L EE+ +K + K E + KE
Sbjct: 1301 DDKREEQSEKVHEEREIVLNIEQPQEEEKKEELHEEEEKKEELHEEEEKKEELHEEEKKE 1360
Query: 2435 KIKEECQIDDEIKDKKMEAPLVAQTKGEVNMQTEEHLNLEKDSEMGIENTEQKISVXXXX 2256
++ EE + ++++ +++ E TK E++ + EE + + E E E++
Sbjct: 1361 ELHEEEKKEEQLHEEEEE------TKEELHEEEEEKIEKLHEEEKKEELHEEEKK--EEQ 1412
Query: 2255 XXXXXXEQKDADVSLEREKIIELNEYKENNRSETSDSGLKETKFESEEEF---DACSKEL 2085
E+K+ + E EK EL+E E + E + KE E EEE + +E
Sbjct: 1413 LHEEEEEKKEEQLHEEEEKKEELHE--EEKKEELHEEEKKEELHEEEEEEKKEELHEEEE 1470
Query: 2084 ETTGTCANIETDILEQEEDALKKLDQNLESEKGTMKVEEIQVEVKATDHSHKINESHNTA 1905
E + E + E+EE+ ++KL + E EK EE+ E + K E H
Sbjct: 1471 EEKKEELHEEEEKKEEEEEKIEKLHEEEEEEKK----EELHEE----EEEEKKEELHEEE 1522
Query: 1904 ESALLAQDNLEAIDPCDEIKRDTESTDHDQSKEALSEIEKTEVVEDKEIMKYQNVVSVED 1725
E ++ +E + +E K++ ++ + A+ E+E E E+ + K + ED
Sbjct: 1523 EKKEEEEEKIEKLHEEEEKKKE-QTNEEINYNPAIKEVEGPESEEENKYRKDEE--DFED 1579
Query: 1724 HTVGES-IQDEENENDSLDEAGPKLNANDQNDDMNDVNPPIKDAIVNEEMPHGVERADNG 1548
ES + ++ E++S+ + + + ++N++ + N P ++ +
Sbjct: 1580 EKNEESDYKKQKEESESVAKELEETSTENRNNNQEETNQP--------KLENSSLNITEV 1631
Query: 1547 REETLVGEVGEQCKVDPNFESDLQNEGADKGNDEEDKCRKLDAXXXXXXXXXXXXXXVGK 1368
+EET E+ + +FE++ QNE D E A K
Sbjct: 1632 KEET-----EEKVNITDDFETENQNE------DRETDAETEKAIHQENEQIREKDFHDEK 1680
Query: 1367 QLEEESDLVPGELINEIVTNRTENEGGAPKDTTDTDGVIDVNKPAESTFSTNTTSTIEKL 1188
Q+E E + E++ E + R + KD + + + K IEKL
Sbjct: 1681 QIENEEE--KQEILKEPIEERNFQQENDFKDNEEEEKKEEEEK-------------IEKL 1725
Query: 1187 HIDEKLLTDNPDASSLTEASQESMQEKEGKNTEDGEKQEVVFVKKATKDMGLPTEESREN 1008
H E+ + + E E ++KE + E+ EK+E + ++ ++ L EE +E
Sbjct: 1726 HEKEEKIEKLHEEEEKKEELHEEEEKKEEQLHEEEEKKEELHEEEKKEE--LHEEEKKEE 1783
Query: 1007 IEHEAPVAEMSKEGGKKINEVSIEEKS----FRNEEGETQVLKQPDTPRDLQMLDQSSDV 840
+ E E E KK ++ EEK E+ E Q+ ++ L ++ +
Sbjct: 1784 LHEEEKKEEQLHEEEKKEEQLHEEEKKEEQLHEEEKKEEQLHEEEKKEEQLHEEEKKEEQ 1843
Query: 839 TAEQEASIETDSIEKTKENISIGSIEIPSAPVDVIEKSLQTAEV------EEGKHGEV-- 684
E+E E E+ KE + E + E+ + E+ EE H EV
Sbjct: 1844 LHEEEKKEELHEEEEKKEE-QLHEEEEEKKEEQLHEEEEKKEELHEEEKKEEQPHEEVVV 1902
Query: 683 ----------QGNDSELNTVECEASFDEETNTNS----KSSEAKGASLFDLLNKPRKDTG 546
+ D+E + + + FDEE +T K E + + FD + +
Sbjct: 1903 VEEKMEQPQEEEEDNEADGIHSLSDFDEEISTEEKVEIKVQEKEENNDFDAEEEKILEEK 1962
Query: 545 QAVEQFEEEGNSTSNKEQLENKE 477
E EEE N T + +++E
Sbjct: 1963 LEKEIIEEENNETEDDRPKKSEE 1985
Score = 78.6 bits (192), Expect(2) = 4e-42
Identities = 150/740 (20%), Positives = 277/740 (37%), Gaps = 27/740 (3%)
Frame = -3
Query: 5337 VPDLSTTTREEPIEDGHEKNKVIEGLEIASSDKENGDPIIEEVVPDHSTTTIGKESTNDV 5158
+P +S++ +E+ K K EI+SS KE EE+ S++ KE +
Sbjct: 435 LPHISSSRKEKEEISSSRKEKE----EISSSRKEK-----EEI----SSSRKEKEEISSS 481
Query: 5157 HEEDKVVAGL-----DIVGVDKDIGEPVIKDDVVPDRSTTTIEEEPIQDGQAENEVIEGL 4993
+E + ++ +I K+ E + S++ E+E I + E E I
Sbjct: 482 RKEKEEISSSRKEKEEISSSRKEKEEISSSRKEKEEISSSRKEKEEISSSRKEKEEISSS 541
Query: 4992 EKVELDKDFGDPITEKDVAPDYSITTFDEETIKDVHEEDKVIEGAEIGGDNDIGDPVIGE 4813
K + + G K ++TFD E E + E +N+I +I E
Sbjct: 542 RKEKENTQLGLSNIIKG-----KLSTFDVEEKPKEREFEVKKSSEEENKNNEIPSEIITE 596
Query: 4812 EVVPDNSTTTIRGEPIQDDHEEDKMRERLKIDGANKDIVEPTVKDVVLDQSTTTIGETPV 4633
N + E+ ID A K+ + K+ T+ E+
Sbjct: 597 SYNETNDDFESEKPKEEVSKSENDFESEKHIDSAQKE----SEKEQAKQSEETSNLESEF 652
Query: 4632 KDGHGGHKVTAGLERVGADKDIGEPITKENVVSDHPIKTIG--DIKDDHEEDKVIEGLDI 4459
+ HK ++ E + + + +++ +D + G D EE+K+ E +
Sbjct: 653 ESEK--HKESSKEETESDNDKLSDKKQEKDKETDDDFEEEGKKDQITQSEEEKLNEIISS 710
Query: 4458 GGNEDIGEPTIEDGISYHSTTTTWEEPTKDGH----------------EEKVTEGLEIVD 4327
G+++ IE+ + +EE T++ + EEK E +
Sbjct: 711 EGDKEKDFHFIEEKKPNNEIQDDFEEATEEKYSEREELMKPTEPDFQQEEKQKEEVNEEK 770
Query: 4326 TDENSGNHFIEDDVSEHSTTITGEEAIQNG-QEEDKMIEGLEKVDADKDIGEPIIEKDGP 4150
+ N F+E+ E + + I++ +EE K IE E +
Sbjct: 771 QIDRKENDFLEETKEEQIHEVKVSDDIKDDFKEEQKEIEH---------------ESNNA 815
Query: 4149 DHSTTLGAELINDVHDEDKVNEGLERVGSDKDTGEPVIVEDV---VPDNSTRASGEKPIQ 3979
+ ST E++++ +E KV S+++T E ++ D +T E+P +
Sbjct: 816 EESTNKSKEVVSETEEESKVQTKERENPSEEETKEEPFEDEYKEETKDENTEEIKEEPFE 875
Query: 3978 DGHGEEKITERLEIDRTDKEIGEPTMEEGVVLDQSTTIGVEPVVDNYKEHKVTEGLEIIG 3799
D EE + E + ++ + T EE D++ E + KE E E
Sbjct: 876 DETKEENKDKNKEETKEEEPFEDETKEEEPFEDENK----EETKEETKEENKDENKEETK 931
Query: 3798 ENKDIGEPIIEENLVLDHSTTPIVEIKDGHEEDKVIEGSELAGAEDIGEPITEEDVSDHT 3619
E + + EEN + T E KD +E+ E + E+ + T+E+ D
Sbjct: 932 EEEPFEDETKEENKDENKEETK-EETKDKSKEETKEETKDETKEEEPFDGETKEENKDEN 990
Query: 3618 TTTIGKEPTKDVHEEDKAVAFSDLSSADQNFEQVNLSGQTECFEVENLNKHADASTTTHQ 3439
KE KD ++E+ + + ++ FE +T+ + + T +
Sbjct: 991 -----KEENKDENKEETKEENKEETKEEEPFED-----ETKEETKDETKEETKDETKEEE 1040
Query: 3438 VIEDPVKEESDVLSQDRVHEEDGDNPKDEEDNVESFEMSKGQEPAISHQEKTIAEATTLI 3259
ED KEE+ +E+ + EE E+ E +K +EP ++ E T
Sbjct: 1041 PFEDESKEET---------KEENKDENKEETKEETKEETKEEEPFEDENKEETKEETKED 1091
Query: 3258 QKSETESMKLNRTGEPDSTE 3199
+ E E+ + N+ EP E
Sbjct: 1092 EPFEDETKEENKEEEPFEDE 1111
Score = 120 bits (300), Expect = 6e-24
Identities = 193/904 (21%), Positives = 364/904 (40%), Gaps = 30/904 (3%)
Frame = -1
Query: 3098 VSIEEATDSTQETEIVTLEEETPKNSLNDFRATEAPLEEITKMKKSDKLNYTPTESAMSE 2919
VS + D +E + + E + S N + + EE +K++ ++ N P+E E
Sbjct: 793 VSDDIKDDFKEEQKEIEHESNNAEESTNKSKEVVSETEEESKVQTKEREN--PSEEETKE 850
Query: 2918 EQVIKEIPEKTESANHETIFVTQPTEKLSLHEAEPQGGELVDASDDASVEMFST--PIEE 2745
E E E+T+ N E I + EP E + + D + E P E+
Sbjct: 851 EPFEDEYKEETKDENTEEI------------KEEPFEDETKEENKDKNKEETKEEEPFED 898
Query: 2744 HGASSLDPDMEDVKQGEIATLDDNATDNTFTAENAETEHEKPEVPVENSAVATQSVDKDT 2565
+ E+ ++ + T ++N +N E E E + E EN + ++T
Sbjct: 899 ETKEEEPFEDENKEETKEETKEENKDENK--EETKEEEPFEDETKEENKDENKEETKEET 956
Query: 2564 QTTLVSEITASKASSDDLSEEKPQKSSMLISAKNEFNAVGMKEKIKEECQIDDEIKDKKM 2385
+ E + + D+ EE+P K+E N K++ KEE + +++ ++ K
Sbjct: 957 KDKSKEE--TKEETKDETKEEEPFDGETKEENKDE-NKEENKDENKEETKEENK-EETKE 1012
Query: 2384 EAPLVAQTKGEVNMQTEEHLNLEKDSEMGIENTEQKISVXXXXXXXXXXEQKDADVSLER 2205
E P +TK E +T+E E E E+ ++ + +++ +
Sbjct: 1013 EEPFEDETKEETKDETKEETKDETKEEEPFEDESKEETKEENKDENKEETKEETKEETKE 1072
Query: 2204 EKIIELNEYKENNRSETSDSGL--KETKFESEEE--FDACSKELETTGTCANIETDILEQ 2037
E+ E +E KE + ET + ETK E++EE F+ +KE ET + + +
Sbjct: 1073 EEPFE-DENKEETKEETKEDEPFEDETKEENKEEEPFEDENKE-ETKEDNKDDYEEETKH 1130
Query: 2036 EEDALKKLDQNLESEKGTMKVEEIQVEV-KATDHSHKINESHNTAESALLAQDNLEAIDP 1860
E + ++ D+ V+E EV K D E H+ E ++ E I
Sbjct: 1131 ENNVQEQEDEPTNKANPIASVDEEFEEVFKDEDREF---EKHSQEELNREVKEEREFIPQ 1187
Query: 1859 CDEIKRDTESTDHDQSKEALSEIEKTE--VVEDKEIMKYQNVVSVEDHTVGESIQDEENE 1686
DE K D ES +H+ +E + E +K + ++++E K + V + D + E E++E
Sbjct: 1188 KDETK-DQES-NHEDFEEEIKEEQKIDEDTIKEEEEQKTEKVQNDFDEEIKEEDIKEKHE 1245
Query: 1685 NDSLDEAGPKLNANDQNDDMNDVNPPIKDAIVNE------------EMPHGVERADNGRE 1542
+ D+ ND+ +V I++ I + + V+ D+ RE
Sbjct: 1246 EVTKDKVEMNEEQNDEEKQQQEVESTIEEDITEQNVEPKKEEQTIQDFEEEVQNYDDKRE 1305
Query: 1541 ETLVGEVGEQCKVDPNFESDLQNEGADKGNDEEDKCRKL--------DAXXXXXXXXXXX 1386
E +V E+ ++ N E + E ++ ++EE+K +L +
Sbjct: 1306 EQSE-KVHEEREIVLNIEQPQEEEKKEELHEEEEKKEELHEEEEKKEELHEEEKKEELHE 1364
Query: 1385 XXXVGKQLEEESDLVPGELINEIVTNRTENEGGAPKDTTDTDGVIDVNKPAESTFSTNTT 1206
+QL EE + EL E E + + + + + K E
Sbjct: 1365 EEKKEEQLHEEEEETKEELHEE-----EEEKIEKLHEEEKKEELHEEEKKEEQLHEEEEE 1419
Query: 1205 STIEKLHIDEKLLTDNPDASSLTEASQESMQEKEGKNTEDGEKQEVVFVKKATKDMGLPT 1026
E+LH +E+ + + E +E +E+ + E+ +K+E+ ++ K L
Sbjct: 1420 KKEEQLHEEEEKKEELHEEEKKEELHEEEKKEELHEEEEEEKKEELHEEEEEEKKEELHE 1479
Query: 1025 EESRENIEHEAPVAEMSKEGGKKINEVSIEEKSFRNEEGETQVLKQPDTPRDLQMLDQSS 846
EE ++ E E +E +K E+ EE+ + EE + K+ + ++ L +
Sbjct: 1480 EEEKKEEEEEKIEKLHEEEEEEKKEELHEEEEEEKKEELHEEEEKKEEEEEKIEKLHEEE 1539
Query: 845 DVTAEQEASIETDSIEKTKENISIGSIEIP-SAPVDVIEKSLQTAEVEEGKHGEVQGNDS 669
+ EQ + E+ N +I +E P S + K + E E+ + + +
Sbjct: 1540 EKKKEQ-------TNEEINYNPAIKEVEGPESEEENKYRKDEEDFEDEKNEESDYKKQKE 1592
Query: 668 ELNTVECEASFDEETNTNSKSSEAKGASLFDLLNKPRKDTGQAVEQFEEEGNSTSNKEQL 489
E +V E EET+T ++++ + + L N T + E+ EE+ N T + E
Sbjct: 1593 ESESVAKEL---EETSTENRNNNQEETNQPKLENSSLNIT-EVKEETEEKVNITDDFETE 1648
Query: 488 ENKE 477
E
Sbjct: 1649 NQNE 1652
Score = 98.2 bits (243), Expect = 3e-17
Identities = 219/1075 (20%), Positives = 398/1075 (37%), Gaps = 84/1075 (7%)
Frame = -3
Query: 6186 KVTEELKIDGANKDIGEPSIKDVVLDQ-STSSIGETPAKDGHEEHKLVGADKDIGKTIIK 6010
K EE+ K+ + + +++ + ST + E P + E K + K
Sbjct: 533 KEKEEISSSRKEKENTQLGLSNIIKGKLSTFDVEEKPKEREFEVKKSSEEEN-------K 585
Query: 6009 ENVIPDHPI-KTIGEIKHDHEEDKVIEGLDIDCGNEDNGEPITEEDGVRGHSTKTTWEEP 5833
N IP I ++ E D E +K E + +E++ E D + S K E
Sbjct: 586 NNEIPSEIITESYNETNDDFESEKPKEEVS---KSENDFESEKHIDSAQKESEK----EQ 638
Query: 5832 AKDGHEEKVTKGLEIVDTNKNCGKPFIEDDVIPEHSTTITGEKAIRNGQEEDKVIEELEK 5653
AK E + + +K K E D + ++ +K ++ + +D EE +K
Sbjct: 639 AKQSEETSNLESEFESEKHKESSKEETESD-----NDKLSDKKQEKDKETDDDFEEEGKK 693
Query: 5652 ----VDAEENIGEPII-EKDVVPDHATTLGEELINDVHDDDKVIEGFEIVGSDKDTGEPV 5488
EE + E I E D D ++ N++ DD FE +K +
Sbjct: 694 DQITQSEEEKLNEIISSEGDKEKDFHFIEEKKPNNEIQDD------FEEATEEKYSEREE 747
Query: 5487 IVEDVVPEHPTTTSGKESIKDGHXXXXXXXXXXXVGADREIREPVIEEDIVPDL------ 5326
+++ P+ KE + + + +I E + +DI D
Sbjct: 748 LMKPTEPDFQQEEKQKEEVNEEKQIDRKENDFLEETKEEQIHEVKVSDDIKDDFKEEQKE 807
Query: 5325 ----------STTTREEPIEDGHEKNKV-IEGLEIASSDKENGDPIIEEV---VPDHSTT 5188
ST +E + + E++KV + E S ++ +P +E D +T
Sbjct: 808 IEHESNNAEESTNKSKEVVSETEEESKVQTKERENPSEEETKEEPFEDEYKEETKDENTE 867
Query: 5187 TIGKESTNDVHEEDKVVAGLDIVGVDKDIGEPVIKDDVVPDRSTTTIEEEPIQDGQAENE 5008
I +E D +E+ + ++ + +++ D + +EE ++ + EN+
Sbjct: 868 EIKEEPFEDETKEENKDKNKEETKEEEPFEDETKEEEPFEDENKEETKEETKEENKDENK 927
Query: 5007 VIEGLEKVELDKDFGDPITE----------KDVAPDYSITTFDEETIKDVHEEDKVIEGA 4858
E+ + ++ F D E K+ D S EET KD +E++ +G
Sbjct: 928 -----EETKEEEPFEDETKEENKDENKEETKEETKDKSKEETKEET-KDETKEEEPFDGE 981
Query: 4857 EIGGDNDIGDPVIG----EEVVPDNSTTTIRGEPIQDDHEE---DKMRERLKIDGANKDI 4699
+ D EE +N T EP +D+ +E D+ +E K + ++
Sbjct: 982 TKEENKDENKEENKDENKEETKEENKEETKEEEPFEDETKEETKDETKEETKDETKEEEP 1041
Query: 4698 VEPTVKDVVLDQSTTTIGETPVKDGHGGHKVTAGLERVGADKDIGEPITKENVVSDHPIK 4519
E K+ +++ E ++ K E D + TKE D P +
Sbjct: 1042 FEDESKEETKEENKDENKEETKEETKEETKEEEPFE------DENKEETKEETKEDEPFE 1095
Query: 4518 TIGDIKDDHEEDKVIEGLDIGGNEDIGEPTIEDGISYHSTTTTWEEPTKDGHEEKVTEGL 4339
+ K++++E++ E ++ E T ED + T E ++ +E +
Sbjct: 1096 D--ETKEENKEEEPFE-------DENKEETKEDNKDDYEEETKHENNVQEQEDEPTNKAN 1146
Query: 4338 EIVDTDENSGNHFIEDD--VSEHSTTITGEEAIQ----------------NGQEEDKMIE 4213
I DE F ++D +HS E + N ++ ++ I+
Sbjct: 1147 PIASVDEEFEEVFKDEDREFEKHSQEELNREVKEEREFIPQKDETKDQESNHEDFEEEIK 1206
Query: 4212 GLEKVDAD--KDIGEPIIEKDGPDHSTTLGAELINDVHDE---DKVNEGLERVGSDKDTG 4048
+K+D D K+ E EK D + E I + H+E DKV E+ +K
Sbjct: 1207 EEQKIDEDTIKEEEEQKTEKVQNDFDEEIKEEDIKEKHEEVTKDKVEMNEEQNDEEKQQQ 1266
Query: 4047 E--PVIVEDVVPDNSTRASGEKPIQDGHGE------------EKITERLEIDRTDKEIGE 3910
E I ED+ N E+ IQD E EK+ E EI ++ E
Sbjct: 1267 EVESTIEEDITEQNVEPKKEEQTIQDFEEEVQNYDDKREEQSEKVHEEREIVLNIEQPQE 1326
Query: 3909 PTMEEGVVLDQSTTIGVEPVVDNYKEHKVTEGLEIIGENKDIGEPIIEENLVLDHSTTPI 3730
+E + ++ + + +E E E + E + E + EE
Sbjct: 1327 EEKKEELHEEEEKKEELHEEEEKKEELHEEEKKEELHEEEKKEEQLHEEEEETKEELHEE 1386
Query: 3729 VE--IKDGHEEDKVIEGSELAGAEDIGEPITEEDVSDHTTTTIGKEPTKD-VHEEDKAVA 3559
E I+ HEE+K EL E E + EE+ +E K+ +HEE+K
Sbjct: 1387 EEEKIEKLHEEEKK---EELHEEEKKEEQLHEEEEEKKEEQLHEEEEKKEELHEEEKKEE 1443
Query: 3558 FSDLSSADQNFEQVNLSGQTECFEVENLNKHADASTTTHQVIEDPVKEESDVLSQDRVHE 3379
+ ++ E+ + E E E K ++ E+ K+E + +++HE
Sbjct: 1444 LHEEEKKEELHEEEEEEKKEELHEEEEEEK-------KEELHEEEEKKEEEEEKIEKLHE 1496
Query: 3378 EDGDNPKDEEDNVESFEMSKGQEPAISHQEKTIAEATTLIQKSETESMKLNRTGE 3214
E+ + K+E + E + +E +EK E + + E E K +T E
Sbjct: 1497 EEEEEKKEE---LHEEEEEEKKEELHEEEEKKEEEEEKIEKLHEEEEKKKEQTNE 1548
Score = 97.4 bits (241), Expect = 4e-17
Identities = 217/1042 (20%), Positives = 390/1042 (37%), Gaps = 162/1042 (15%)
Frame = -1
Query: 3113 KESDLVSIEEATDSTQETEIVTLEEETPKNSLNDF--------RATEAPLE--------- 2985
KE L I + +TE++ E E PK++ + R P+E
Sbjct: 293 KEKKLAPIYSSVQPEYQTELLLPEIEPPKDTWEAYTNERKQKQRYDTRPIEERPPSSFWS 352
Query: 2984 -----------EITKMKKSDK-------LNYTPTESAMSEEQVIKEIPEK---------- 2889
E + KK D+ + P SA + P+K
Sbjct: 353 SIPKGLAESAREAMEQKKKDEAFMRKPDVAKRPKTSAEVSPPFSSKPPQKIQQNLAPTRL 412
Query: 2888 -----TESANHETIFVTQPTEKLSLHEAEPQGGELVDASDDASVEMFSTPIEEHGASSLD 2724
+ES+N + + +EKL + + E + +S E+ S+ E+ SS
Sbjct: 413 SLRRSSESSNQSSQVSSSRSEKLPHISSSRKEKEEISSSRKEKEEISSSRKEKEEISSSR 472
Query: 2723 PDMEDV-----KQGEIAT----LDDNATDNTFTAENAETEHEKPEVP------------- 2610
+ E++ ++ EI++ ++ ++ E + + EK E+
Sbjct: 473 KEKEEISSSRKEKEEISSSRKEKEEISSSRKEKEEISSSRKEKEEISSSRKEKEEISSSR 532
Query: 2609 VENSAVATQSVDKDTQTTLVSEITASKASSDDLSEEKPQK-------------------S 2487
E +++ +K+ +S I K S+ D+ EEKP++ S
Sbjct: 533 KEKEEISSSRKEKENTQLGLSNIIKGKLSTFDV-EEKPKEREFEVKKSSEEENKNNEIPS 591
Query: 2486 SMLISAKNEFNAVGMKEKIKEE-CQIDDEIKDKKMEAPLVAQTKGEVNMQTEEHLNL--- 2319
++ + NE N EK KEE + +++ + +K +++ E Q+EE NL
Sbjct: 592 EIITESYNETNDDFESEKPKEEVSKSENDFESEKHIDSAQKESEKEQAKQSEETSNLESE 651
Query: 2318 ---EKDSEMGIENTE---QKIS------VXXXXXXXXXXEQKDADVSLEREKIIE----- 2190
EK E E TE K+S +KD E EK+ E
Sbjct: 652 FESEKHKESSKEETESDNDKLSDKKQEKDKETDDDFEEEGKKDQITQSEEEKLNEIISSE 711
Query: 2189 ---------LNEYKENNRSETSDSGLKETKFESEEE--------FDACSKELETTGTCAN 2061
+ E K NN + E K+ EE F K+ E
Sbjct: 712 GDKEKDFHFIEEKKPNNEIQDDFEEATEEKYSEREELMKPTEPDFQQEEKQKEEVNEEKQ 771
Query: 2060 I---ETDILEQEEDALKKLDQNLESEKGTMKVEEIQVEVKATDHSHKINESH-------- 1914
I E D LE+ ++ + + K K E+ ++E ++ + N+S
Sbjct: 772 IDRKENDFLEETKEEQIHEVKVSDDIKDDFKEEQKEIEHESNNAEESTNKSKEVVSETEE 831
Query: 1913 ----NTAESALLAQDNLEAIDPCDEIKRDTESTDHDQSKEALSEIEKTEVVEDKEIMKYQ 1746
T E +++ + DE K +T+ + ++ KE E E E +DK + +
Sbjct: 832 ESKVQTKERENPSEEETKEEPFEDEYKEETKDENTEEIKEEPFEDETKEENKDKNKEETK 891
Query: 1745 NVVSVEDHTVGESIQDEENENDSLDEAGPKLNANDQNDDMNDVNPPIKDAIVNEEMPHGV 1566
ED T E ++EN+ ++ +E K D+N + P +D E
Sbjct: 892 EEEPFEDETKEEEPFEDENKEETKEET--KEENKDENKEETKEEEPFEDETKEENKDENK 949
Query: 1565 ERA-----DNGREETLVGEVGEQCKVDPNFESDLQNEGADKGNDEEDKCRKLDAXXXXXX 1401
E D +EET E ++ K + F+ + + E D+ +E K +
Sbjct: 950 EETKEETKDKSKEET-KEETKDETKEEEPFDGETKEENKDENKEENKDENKEETKEENKE 1008
Query: 1400 XXXXXXXXVGKQLEEESDLVPGELINEIVTNRTENEGGAPKDTTDTDGVIDVNKPAESTF 1221
+ EE D E +E T E K+ T + D NK E T
Sbjct: 1009 ETKEEEPFEDETKEETKDETKEETKDE--TKEEEPFEDESKEETKEENK-DENK--EETK 1063
Query: 1220 STNTTSTIEKLHIDEKLLTDNPDASSLTEASQESMQE--KEGKNTEDGEKQEVVFVKKAT 1047
T E+ +++ + + + E ++ +E KE + ED K+E K+
Sbjct: 1064 EETKEETKEEEPFEDENKEETKEETKEDEPFEDETKEENKEEEPFEDENKEE---TKEDN 1120
Query: 1046 KDMGLPTEESRENIEHEAPVAEMSKEGGKKINEV-SIE---EKSFRNEEGETQVLKQPDT 879
KD + E +HE V E E K N + S++ E+ F++E+ E + Q +
Sbjct: 1121 KD------DYEEETKHENNVQEQEDEPTNKANPIASVDEEFEEVFKDEDREFEKHSQEEL 1174
Query: 878 PRDLQMLDQ---SSDVTAEQEASIETDSIEKTKENISIGSIEIPSAPVDVIEKSLQTAEV 708
R+++ + D T +QE++ E D E+ KE I I EK +Q
Sbjct: 1175 NREVKEEREFIPQKDETKDQESNHE-DFEEEIKEEQKIDEDTIKEEEEQKTEK-VQNDFD 1232
Query: 707 EEGKHGEVQGNDSELNTVECEASFDEETNTNSKSSEAKGASLFDLLN----KPRKDTGQA 540
EE K +++ E+ + E +EE N K + +++ + + +P+K+ Q
Sbjct: 1233 EEIKEEDIKEKHEEVTKDKVE--MNEEQNDEEKQQQEVESTIEEDITEQNVEPKKEE-QT 1289
Query: 539 VEQFEEEGNSTSNKEQLENKEV 474
++ FEEE + +K + ++++V
Sbjct: 1290 IQDFEEEVQNYDDKREEQSEKV 1311
Score = 92.0 bits (227), Expect = 2e-15
Identities = 230/1165 (19%), Positives = 433/1165 (37%), Gaps = 87/1165 (7%)
Frame = -3
Query: 6447 EGLENVDLDKDIGEPITEKDVAPDHSITAFEE------EPIKYVHEEDKV-IEGTEIIGA 6289
E + V + DI + E+ +H EE E + EE KV + E
Sbjct: 786 EQIHEVKVSDDIKDDFKEEQKEIEHESNNAEESTNKSKEVVSETEEESKVQTKERENPSE 845
Query: 6288 DKDIGDPIIGE--EIVPDHSTTTIRGEPIQDDHEE-----------------DKVTEELK 6166
++ +P E E D +T I+ EP +D+ +E D+ EE
Sbjct: 846 EETKEEPFEDEYKEETKDENTEEIKEEPFEDETKEENKDKNKEETKEEEPFEDETKEEEP 905
Query: 6165 IDGANKDIGEPSIKDVVLDQSTSSIGET-PAKDGHEEHKLVGADKDIGKTIIKENVIPDH 5989
+ NK+ + K+ D++ E P +D +E +KD K KE
Sbjct: 906 FEDENKEETKEETKEENKDENKEETKEEEPFEDETKEE-----NKDENKEETKEETKDKS 960
Query: 5988 PIKTIGEIKHDHEEDKVIEGLDIDCGNEDNGEPITEE---DGVRGHSTKTTWEEPAKDGH 5818
+T E K + +E++ +G + ++N E +E + + +T EEP +D
Sbjct: 961 KEETKEETKDETKEEEPFDGETKEENKDENKEENKDENKEETKEENKEETKEEEPFEDET 1020
Query: 5817 EEKVTKGLEIVDTNKNCGKPFIEDDVIPEHSTTITGEKAIRNGQEEDKVIEELEKVDAEE 5638
+E+ +T + E++ + S T E+ +EE K EE ++ EE
Sbjct: 1021 KEETKD-----ETKEETKDETKEEEPFEDESKEETKEENKDENKEETK--EETKEETKEE 1073
Query: 5637 NIGEPIIEKDVVPDHATTLGEELIND-VHDDDKVIEGFEIVGSDKDTGEPVIVEDVVPEH 5461
EP +++ T +E D +++K E FE D + ED ++
Sbjct: 1074 ---EPFEDENKEETKEETKEDEPFEDETKEENKEEEPFE------DENKEETKEDNKDDY 1124
Query: 5460 PTTTSGKESIKDGHXXXXXXXXXXXVGADREIREPVIEEDIVPDLSTTTREEPIEDGHEK 5281
T + ++++ D E E +ED + ++EE + E+
Sbjct: 1125 EEETKHENNVQE-QEDEPTNKANPIASVDEEFEEVFKDED--REFEKHSQEELNREVKEE 1181
Query: 5280 NKVIEGLEIASSDKENGDPIIEEVVPDHSTTTIGKESTNDVHEEDKVVAGLDIVGVDKDI 5101
+ I + + N + EE+ + E T EE K V D
Sbjct: 1182 REFIPQKDETKDQESNHEDFEEEIKEEQKID----EDTIKEEEEQKTEK------VQNDF 1231
Query: 5100 GEPVIKDDVVPDRSTTTIEEEPIQDGQAENEVIEGLEKVELDKDFGDPITEKDVAP---D 4930
E + ++D+ T ++ + + Q + E ++ E++ + ITE++V P +
Sbjct: 1232 DEEIKEEDIKEKHEEVTKDKVEMNEEQNDEEK----QQQEVESTIEEDITEQNVEPKKEE 1287
Query: 4929 YSITTFDEET----------IKDVHEEDKVIEGAEIGGDNDIGDPVIGEEVVPDNSTTTI 4780
+I F+EE + VHEE +++ E + + + + EE
Sbjct: 1288 QTIQDFEEEVQNYDDKREEQSEKVHEEREIVLNIEQPQEEEKKEELHEEE---------- 1337
Query: 4779 RGEPIQDDHEEDKMRERLKIDGANKDIVEPTVKDVVLDQSTTTIGET-------PVKDGH 4621
E ++ HEE++ +E L + +++ E K+ L + E ++ H
Sbjct: 1338 --EKKEELHEEEEKKEELHEEEKKEELHEEEKKEEQLHEEEEETKEELHEEEEEKIEKLH 1395
Query: 4620 GGHKVTAGLERVGADKDIGEPITKENVVSDHPIKTIGDIKDD----------HEEDKVIE 4471
K E ++ + E +E + + + K++ HEE+K E
Sbjct: 1396 EEEKKEELHEEEKKEEQLHE---EEEEKKEEQLHEEEEKKEELHEEEKKEELHEEEKK-E 1451
Query: 4470 GLDIGGNEDIGEPTIEDGISYHSTTTTWEEPTKDGHEEKVTEGLEIVDTDENSGNHFIED 4291
L E+ E E+ EE K+ EEK+ + E + +E E+
Sbjct: 1452 ELHEEEEEEKKEELHEEEEEEKKEELHEEEEKKEEEEEKIEKLHE--EEEEEKKEELHEE 1509
Query: 4290 DVSEHSTTITGEEAIQNGQEEDKMIEGL--------EKVDADKDIGEPIIEKDGPDHSTT 4135
+ E + EE + +EE++ IE L E+ + + + I E +GP+
Sbjct: 1510 EEEEKKEELHEEE--EKKEEEEEKIEKLHEEEEKKKEQTNEEINYNPAIKEVEGPESEEE 1567
Query: 4134 LGAELINDVHD-EDKVNEGLERVGSDKDTGEPVIVEDVVPDNSTRASGEKPIQDGHGEEK 3958
+ D D ED+ NE + K+ E V E R + ++ E
Sbjct: 1568 --NKYRKDEEDFEDEKNEESD-YKKQKEESESVAKELEETSTENRNNNQEETNQPKLENS 1624
Query: 3957 ---ITERLEIDRTDKEIGEPTMEEGVVLDQSTTIGVEPVV----DNYKEHKVTEGLEIIG 3799
ITE E I + E D+ T E + + +E + +I
Sbjct: 1625 SLNITEVKEETEEKVNITDDFETENQNEDRETDAETEKAIHQENEQIREKDFHDEKQIEN 1684
Query: 3798 ENKD---IGEPIIEENLVLDHSTTPIVEIKDGHEEDKVIEGSE-------LAGAEDIGEP 3649
E + + EPI E N ++ E + EE+K+ + E L E+ E
Sbjct: 1685 EEEKQEILKEPIEERNFQQENDFKDNEEEEKKEEEEKIEKLHEKEEKIEKLHEEEEKKEE 1744
Query: 3648 ITEEDVSDHTTTTIGKEPTKDVHEEDKAVAFSDLSSADQNFEQVNLSGQTECFEVENLNK 3469
+ EE+ +E +++HEE+K + ++ E+ Q E +
Sbjct: 1745 LHEEEEKKEEQLHEEEEKKEELHEEEKKEELHEEEKKEELHEEEKKEEQLHEEEKKEEQL 1804
Query: 3468 HADASTTTHQVIEDPVKEESDVLSQDRVHEEDGDNPKDEEDNVESFEMSKGQEPAISHQE 3289
H + Q+ E+ KEE ++HEE+ + E+ + ++ + ++ H+E
Sbjct: 1805 HEEEKKE-EQLHEEEKKEE-------QLHEEEKKEEQLHEEEKKEEQLHEEEKKEELHEE 1856
Query: 3288 KTIAEATTLIQKSETESMKLNRTGE 3214
+ E ++ E + +L+ E
Sbjct: 1857 EEKKEEQLHEEEEEKKEEQLHEEEE 1881
Score = 90.5 bits (223), Expect = 5e-15
Identities = 154/816 (18%), Positives = 316/816 (38%), Gaps = 8/816 (0%)
Frame = -1
Query: 3089 EEATDSTQETEIV--TLEEETPKNSLNDFRATEAPLEEITKMKKSDKLNYTPTESAMSEE 2916
EE D ++ + V T+EE+ + ++ + + + +++ D +E E
Sbjct: 1256 EEQNDEEKQQQEVESTIEEDITEQNVEPKKEEQTIQDFEEEVQNYDDKREEQSEKVHEER 1315
Query: 2915 QVIKEIPEKTESANHETIFVTQPTEKLSLHEAEPQGGELVDASDDASVEMFSTPIEEHGA 2736
+++ I + E E + + +K LHE E + EL + ++ E+ EE
Sbjct: 1316 EIVLNIEQPQEEEKKEELH-EEEEKKEELHEEEEKKEELHE--EEKKEELHE---EEKKE 1369
Query: 2735 SSLDPDMEDVKQGEIATLDDNATDNTFTAENAETEHEKPEVPVENSAVATQSVDKDTQTT 2556
L + E+ K+ E+ ++ + E E HE+ + + + ++ +
Sbjct: 1370 EQLHEEEEETKE-ELHEEEEEKIEKLHEEEKKEELHEEEK--------KEEQLHEEEEEK 1420
Query: 2555 LVSEITASKASSDDLSEEKPQKSSMLISAKNEFNAVGMKEKIKEECQIDDEIKDKKMEAP 2376
++ + ++L EE+ ++ K E + +EK KEE ++E + K+
Sbjct: 1421 KEEQLHEEEEKKEELHEEEKKEELHEEEKKEELHEEEEEEK-KEELHEEEEEEKKE---- 1475
Query: 2375 LVAQTKGEVNMQTEEHLNLEKDSEMGIENTEQKISVXXXXXXXXXXEQKDADVSLEREKI 2196
+ E + EE +EK E E ++++ +++ E EKI
Sbjct: 1476 ---ELHEEEEKKEEEEEKIEKLHEEEEEEKKEELHEEEEEEKKEELHEEEEKKEEEEEKI 1532
Query: 2195 IELNEYKENNRSETSDS-----GLKETKFESEEEFDACSKELETTGTCANIETDILEQEE 2031
+L+E +E + +T++ +KE + EE + K+ E N E+D +Q+E
Sbjct: 1533 EKLHEEEEKKKEQTNEEINYNPAIKEVEGPESEEENKYRKDEEDFEDEKNEESDYKKQKE 1592
Query: 2030 DALKKLDQNLESEKGTMKVEEIQVEVKATDHSHKINESHNTAESALLAQDNLEAIDPCDE 1851
ESE ++EE E + N + L +L + +E
Sbjct: 1593 ----------ESESVAKELEETSTENR--------NNNQEETNQPKLENSSLNITEVKEE 1634
Query: 1850 IKRDTESTDHDQSKEALSEIEKTEVVEDKEIMKYQNVVSVEDHTVGESIQDEENENDSLD 1671
+ TD D E +E +T+ +K I + + +D + I++EE + + L
Sbjct: 1635 TEEKVNITD-DFETENQNEDRETDAETEKAIHQENEQIREKDFHDEKQIENEEEKQEILK 1693
Query: 1670 EAGPKLNANDQNDDMNDVNPPIKDAIVNEEMPHGVERADNGREETLVGEVGEQCKVDPNF 1491
E + N +ND ++ K+ E H +EE + E+ K +
Sbjct: 1694 EPIEERNFQQENDFKDNEEEEKKEEEEKIEKLHE-------KEEKIEKLHEEEEKKEELH 1746
Query: 1490 ESDLQNEGADKGNDEEDKCRKLDAXXXXXXXXXXXXXXVGKQLEEESDLVPGELINEIVT 1311
E + + E ++ ++EE+K +L + E++ +L E E +
Sbjct: 1747 EEEEKKE--EQLHEEEEKKEELHEEEKKEELH---------EEEKKEELHEEEKKEEQLH 1795
Query: 1310 NRTENEGGAPKDTTDTDGVIDVNKPAESTFSTNTTSTIEKLHIDEKLLTDNPDASSLTEA 1131
+ E ++ + + + K E E+LH +EK + E
Sbjct: 1796 EEEKKEEQLHEEEKKEEQLHEEEKKEEQLHEEEKKE--EQLHEEEKKEEQLHEEEKKEEL 1853
Query: 1130 SQESMQEKEGKNTEDGEKQEVVFVKKATKDMGLPTEESRENIEHEAPVAEMSKEGGKKIN 951
+E +++E + E+ EK+E ++ K L EE +E HE V K +
Sbjct: 1854 HEEEEKKEEQLHEEEEEKKEEQLHEEEEKKEELHEEEKKEEQPHEEVVVVEEKMEQPQEE 1913
Query: 950 EVSIEEKSFRN-EEGETQVLKQPDTPRDLQMLDQSSDVTAEQEASIETDSIEKTKENISI 774
E E + + + ++ + +Q ++++D AE+E +E + +EK
Sbjct: 1914 EEDNEADGIHSLSDFDEEISTEEKVEIKVQEKEENNDFDAEEEKILE-EKLEK------- 1965
Query: 773 GSIEIPSAPVDVIEKSLQTAEVEEGKHGEVQGNDSE 666
++IE+ E + K E + +D E
Sbjct: 1966 ----------EIIEEENNETEDDRPKKSEEEEDDFE 1991
Score = 70.1 bits (170), Expect = 8e-09
Identities = 164/780 (21%), Positives = 310/780 (39%), Gaps = 16/780 (2%)
Frame = -3
Query: 6447 EGLENVDLDKDIGEPITEKDVAP---DHSITAFEEEPIKYVHEEDKVIEGTEIIGADKDI 6277
E + +++ I E ITE++V P + +I FEEE Y +DK E +E + +++I
Sbjct: 1261 EEKQQQEVESTIEEDITEQNVEPKKEEQTIQDFEEEVQNY---DDKREEQSEKVHEEREI 1317
Query: 6276 GDPIIGEEIVPDHSTTTIRGEPIQDDHEEDKVTEELKIDGANKDIGEPSIKDVVLDQSTS 6097
I + E ++ HEE++ EEL + +++ E K+ L +
Sbjct: 1318 VLNIEQPQEEEKKEELHEEEEKKEELHEEEEKKEELHEEEKKEELHEEEKKEEQLHEEE- 1376
Query: 6096 SIGETPAKDGHEEHKLVGADKDIGKTIIKENVIPDHPIKTIGEIKHDHEEDKVIEGLDID 5917
E ++ HEE ++ I K +E H + E H+ EE+K E L +
Sbjct: 1377 ---EETKEELHEEE-----EEKIEKLHEEEKKEELHEEEKKEEQLHEEEEEKKEEQLHEE 1428
Query: 5916 CGNEDNGEPITEEDGVRGHSTKTTWEEPAKDGHEEKVTKGLEIVDTNKNCGKPFIEDDVI 5737
E+ E + EE+ + EE ++ EEK + E + K ++++
Sbjct: 1429 ---EEKKEELHEEEKKEELHEEEKKEELHEEEEEEKKEELHEEEEEEK-------KEELH 1478
Query: 5736 PEHSTTITGEKAIR--NGQEEDKVIEELEKVDAEENIGEPIIEKDVVPDHATTLGEELIN 5563
E E+ I + +EE++ EEL + + EE E E++ + EE I
Sbjct: 1479 EEEEKKEEEEEKIEKLHEEEEEEKKEELHEEEEEEKKEELHEEEEKKEEE-----EEKIE 1533
Query: 5562 DVHDDDKVIEGFEIVGSDKDTGEPVIVEDVVPEHPTTTSGKESIKDGHXXXXXXXXXXXV 5383
+H+++ E + +++ P I E E P + + KD
Sbjct: 1534 KLHEEE---EKKKEQTNEEINYNPAIKE---VEGPESEEENKYRKDEEDFEDEKNEESDY 1587
Query: 5382 GADREIREPVIEEDIVPDLSTTTREEPIEDGHEKNKVIEGLEIASSDKENGDPIIEEVVP 5203
+E E V +E + + ST R E+ ++ L I +E + + +
Sbjct: 1588 KKQKEESESVAKE--LEETSTENRNNNQEETNQPKLENSSLNITEVKEETEEKV--NITD 1643
Query: 5202 DHSTTTIGKESTND------VHEEDKVVAGLDIVGVDKDIGEPVIKDDVVPDRSTTTIEE 5041
D T ++ D +H+E++ + +KD + + + + I +
Sbjct: 1644 DFETENQNEDRETDAETEKAIHQENEQIR-------EKDFHD---EKQIENEEEKQEILK 1693
Query: 5040 EPIQDGQAENEVIEGLEKVELDKDFGDPITEKDVAPDYSITTF--DEETIKDVHEEDKVI 4867
EPI++ + E DF D E+ + I EE I+ +HEE++
Sbjct: 1694 EPIEERNFQQE-----------NDFKDNEEEEKKEEEEKIEKLHEKEEKIEKLHEEEEKK 1742
Query: 4866 EGAEIGGDNDIGDPVIGEEVVPDNSTTTIRGEPIQDDHEEDKMRERLKIDGANKDIVEPT 4687
E E+ + + + + EE + E ++ HEE+K E + + + + E
Sbjct: 1743 E--ELHEEEEKKEEQLHEE--EEKKEELHEEEKKEELHEEEKKEELHEEEKKEEQLHEEE 1798
Query: 4686 VKDVVLDQSTTTIGETPVKDGHGGHKVTAGL-ERVGADKDIGEPITKENVVSDHPIKTIG 4510
K+ L + E + H K L E ++ + E KE + + K
Sbjct: 1799 KKEEQLHEE-----EKKEEQLHEEEKKEEQLHEEEKKEEQLHEEEKKEEQLHEEEKKEEL 1853
Query: 4509 DIKDDHEEDKVIEGLDIGGNEDIGEPTIEDGISYHSTTTTWEEPTKD--GHEEKVTEGLE 4336
+++ +E+++ E + E + E E H E+P ++ EEK+ + E
Sbjct: 1854 HEEEEKKEEQLHEEEEEKKEEQLHEEE-EKKEELHEEEKKEEQPHEEVVVVEEKMEQPQE 1912
Query: 4335 IVDTDENSGNHFIEDDVSEHSTTITGEEAIQNGQEEDKMIEGLEKVDADKDIGEPIIEKD 4156
+ +E G H + D E ST E +Q +E + EK+ +K + + IIE++
Sbjct: 1913 EEEDNEADGIHSLSDFDEEISTEEKVEIKVQEKEENNDFDAEEEKILEEK-LEKEIIEEE 1971
Score = 65.9 bits (159), Expect = 1e-07
Identities = 125/634 (19%), Positives = 243/634 (38%), Gaps = 8/634 (1%)
Frame = -3
Query: 5085 KDDVVPDRSTTTIEEEPIQDGQAENEVIEGLEKVELDKDFGDPITEKDVAPDYSITTFDE 4906
+ + +P S++ E+E I + E E I K + ++ EK+ + S + ++
Sbjct: 431 RSEKLPHISSSRKEKEEISSSRKEKEEISSSRKEK--EEISSSRKEKE---EISSSRKEK 485
Query: 4905 ETIKDVHEEDKVIEGAEIGGDNDIGDPVIGEEVVPDNSTTTIRGEPIQDDHEEDKMRERL 4726
E I +E + I + + EE+ S++ E I +E +E +
Sbjct: 486 EEISSSRKEKEEISSSRKEKEEISSSRKEKEEI----SSSRKEKEEISSSRKE---KEEI 538
Query: 4725 KIDGANKDIVEPTVKDVVLDQSTTTIGETPVKDGHGGHKVTAGLERVGADKDIGEPI--- 4555
K+ + + +++ + +T E K+ +V E + +I I
Sbjct: 539 SSSRKEKENTQLGLSNIIKGKLSTFDVEEKPKERE--FEVKKSSEEENKNNEIPSEIITE 596
Query: 4554 ----TKENVVSDHPIKTIGDIKDDHEEDKVIEGLDIGGNEDIGEPTIEDGISYHSTTTTW 4387
T ++ S+ P + + ++D E +K I+ ++ + + E T+
Sbjct: 597 SYNETNDDFESEKPKEEVSKSENDFESEKHIDSAQKESEKEQAKQSEE-------TSNLE 649
Query: 4386 EEPTKDGHEEKVTEGLEIVDTDENSGNHFIEDDVSEHSTTITGEEAIQNGQEEDKMIEGL 4207
E + H+E E E D D+ S +D ++ G++ EE+K+ E +
Sbjct: 650 SEFESEKHKESSKEETES-DNDKLSDKKQEKDKETDDDFEEEGKKDQITQSEEEKLNEII 708
Query: 4206 EKVDADKDIGEPIIEKDGPDHSTTLGAELINDVHDEDKVNEGLERVGSDKDTGEPVIVED 4027
+ DK+ IE+ P+ N++ D+ E +K + +++
Sbjct: 709 SS-EGDKEKDFHFIEEKKPN----------NEIQDD------FEEATEEKYSEREELMKP 751
Query: 4026 VVPDNSTRASGEKPIQDGHGEEKITERLEIDRTDKEIGEPTMEEGVVLDQSTTIGVEPVV 3847
PD Q+ +E++ E +IDR + + E T EE +
Sbjct: 752 TEPDFQ---------QEEKQKEEVNEEKQIDRKENDFLEETKEEQI-------------- 788
Query: 3846 DNYKEHKVTEGLEIIGENKDIGEPIIEENLVLDHSTTPIVEIKDGHEEDKVIEGSELAGA 3667
H+V +I + K+ + I E+ + ST E+ EE+ ++ E
Sbjct: 789 -----HEVKVSDDIKDDFKEEQKEIEHESNNAEESTNKSKEVVSETEEESKVQTKER--- 840
Query: 3666 EDIGEPITEEDVSDHTTTTIGKEPTKDVH-EEDKAVAFSDLSSADQNFEQVNLSGQTECF 3490
E +EE+ + KE TKD + EE K F D + + + + + E F
Sbjct: 841 ----ENPSEEETKEEPFEDEYKEETKDENTEEIKEEPFEDETKEENKDKNKEETKEEEPF 896
Query: 3489 EVENLNKHADASTTTHQVIEDPVKEESDVLSQDRVHEEDGDNPKDEEDNVESFEMSKGQE 3310
E E E+P ++E+ +++ EE+ D K+E E FE +E
Sbjct: 897 EDETKE-------------EEPFEDENKEETKEETKEENKDENKEETKEEEPFEDETKEE 943
Query: 3309 PAISHQEKTIAEATTLIQKSETESMKLNRTGEPD 3208
++E+T E T K ET+ + T E +
Sbjct: 944 NKDENKEET-KEETKDKSKEETKEETKDETKEEE 976
>tpg|DAA02258.1| TPA_exp: S6 sporozoite-induced protein [Plasmodium yoelii]
Length = 2720
Score = 157 bits (396), Expect = 5e-35
Identities = 288/1235 (23%), Positives = 467/1235 (37%), Gaps = 154/1235 (12%)
Frame = -3
Query: 6438 ENVDLDKDIGEPITEKDVAPDHSITAFEEEPIKYVHEEDKVIEGTEIIGADKDIGDPIIG 6259
+ V+ DK + E T +D P H EE+ K VHE K +E + K + D I
Sbjct: 1218 KTVEEDKPVHETKTVEDNIPVHETKTVEED--KPVHET-KTVEDNIPVHETKTVEDNIPT 1274
Query: 6258 ------EEIVPDHSTTTIRGEPIQDDHEEDKVTEELKIDGANKDIGEPSIKDVVLDQSTS 6097
EE +P H T T+ EEDK E K + + E I + + T
Sbjct: 1275 YETKGIEENIPVHETKTV---------EEDKPVHETKAIEEDIPVNESKIVEDMPTYETK 1325
Query: 6096 SIGETPAKDGH--EEHKLVGADKDIG-----KTIIKENVIPDHPIKTIGEIKHDHEEDKV 5938
++ P + EEHK K + +T E IP + KT+ + +E +
Sbjct: 1326 TVENIPVNETKKIEEHKPAYESKLVEDMPTYETKAIEEDIPTYETKTVNDNMPIYETKTL 1385
Query: 5937 IEGLDIDCGNEDNGEPITEEDGVRGHST--KTTWEEPAKDGHEEKVTKGLEIVDTNK-NC 5767
E + + P E + H +T E K +E K+ + + +T
Sbjct: 1386 EEDIPVHETKIVEDMPTYETKTIDEHKPLDETKTIEEHKPAYESKIVEDMPTYETKTVEE 1445
Query: 5766 GKPFIEDDVIPEH-----STTITGEKAIRNGQ--EEDKVIEELEKVDAEENIGEPIIEKD 5608
KP E I EH + TI K+ Q EEDK E + V+ + E ++
Sbjct: 1446 DKPLHETKTIDEHKPLDETKTIEEHKSTHESQIVEEDKPAYETKTVEQSIPVHETKAIEE 1505
Query: 5607 VVPDHATTLGEELINDVHDDDKVIEGFEIVGSDKDTGEPVIVEDVVPEHPTTTSGKESIK 5428
+P + T EE I VH+ V E DK E VE +P H T +E+I
Sbjct: 1506 NIPAYETKTVEENI-PVHETKTVEE-------DKPVYETKTVEQSIPVHETKAI-EENIP 1556
Query: 5427 DGHXXXXXXXXXXXVGADREIREPVIEEDIVPDLSTTTREEPIEDG--HEKNKVIEGLEI 5254
E +P E IV D+ T + ED HE V E +
Sbjct: 1557 ------------AYESKTVEEDKPAYESKIVEDMPTYETKTVEEDKPVHETKTVEEDIPT 1604
Query: 5253 ASSDKENGDP------IIEEVVPDHSTTTIGKEST---NDVHEEDKVVAGLDIVGVDKDI 5101
+ D +IEE +P H T T+ ++ + EED V DK +
Sbjct: 1605 YETKTVEEDKPVYESKVIEEDIPVHETKTVEEDKPVYETKIVEEDIPTYETKTVEEDKPV 1664
Query: 5100 GEPVIKDDVVPDRSTTTIEEE-PIQDGQA--ENEVIEGLEKVELDKDFGDPITEKDVAPD 4930
E + ++ +P T T+EE+ P+ + +A E+ + + VE DK + T D P
Sbjct: 1665 YESKVIEENIPVHETKTVEEDKPVHETKAIEEDIPVHETKTVEEDKPVYETKTVDDNMPT 1724
Query: 4929 YSITTFDEETIKDVHEEDKVIEGAEIGGDNDIGDPVIGEEVVPDNSTTTIRGEPIQDDHE 4750
Y +E VHE K++E D + + EE P T T+ + +E
Sbjct: 1725 YETKGIEENM--PVHET-KIVEE-----DKPLEETKTIEEHKPTYETKTV--DDNMPTYE 1774
Query: 4749 EDKMRERLKIDGANKDIVEPTVKDVVLDQSTTTIGET-PVKDGHGGHKVTAGLERVGADK 4573
+ E + + T+++ + T T+ + P+ + + E G ++
Sbjct: 1775 TKGIEENIPVHETK------TIEEDIPTYETKTVNDNMPIYESKTVEEDKPTYETKGIEE 1828
Query: 4572 DIGEPITKENVVSDHPIKTIGDIKDDH--------EEDK-VIEGLDIGGNEDIGEPTIED 4420
+I TK V D P+ I++D EEDK V E I ++ + E I +
Sbjct: 1829 NIPVHETK-TVEEDKPVHETKAIEEDIPAYESKIVEEDKPVYETKTIDEDKPVYETKIVE 1887
Query: 4419 GISYHSTTTTWEEPTKDGHEEKVTEGLEIVDT---DENSGNH---FIEDDVSEHSTTITG 4258
T T EE K +E K+ E + +T DE+ H +EDD+ H T +
Sbjct: 1888 EYKPLEETKTIEEH-KPTYETKIVEDMPTYETKTLDEHKHVHESKIVEDDIPVHETKVIE 1946
Query: 4257 EEAIQNGQ---EEDKMIEGLEKVDAD------KDIGEPI-------IEKDGPDHSTTLGA 4126
E + EED + + V+ D K + E I +E+D P H T
Sbjct: 1947 EHKPLDENKVIEEDIPVYETKTVEEDNPTYETKTVEENIPVYENKTVEEDIPVHETKTIE 2006
Query: 4125 ELI----NDVHDEDKVNEGLERVGSDKDTGEPVIVEDVVPDNSTRASGEK-PIQDG---- 3973
E+I N V DE K E + + D E ++++V+P + T+ E P+ +
Sbjct: 2007 EVIPTYENKVIDEHKPFEETKTIEEDISLDENKVIDEVIPLHETKTVEEGIPVHENNTVE 2066
Query: 3972 -----HGEEKITERLEIDRTDKEIGE----PTMEEGVVLDQSTTIGVEPVV--------- 3847
H + I E ++ T K I E T++ ++D+ +I ++
Sbjct: 2067 EIIPVHESKTIKEHKPLEET-KTIEEHKPVDTIDASDIIDKGISIDDNKIIQENGGRISD 2125
Query: 3846 --------DNYKEHKVTEGLEIIGENKDIGEPIIEENLVLDHSTTPIVE-----IKDGHE 3706
D Y+ K T + +N++ E II N +D ST+ I+ I G
Sbjct: 2126 KDEAIENLDGYESTKSTNYSDNSDDNEE--EEIIVPNQNIDSSTSNIINDQSKIIYTGKS 2183
Query: 3705 EDKVIEGS----------------ELAGAEDIGEPITEEDV------SDHTTTTIGKEPT 3592
+K + E +D+ I ++ + +D I ++
Sbjct: 2184 VNKTLNSDSDENMHMESRKEDIQKESENNKDVVSHIPDDKIIHGVVNNDEKKLLIDEKNI 2243
Query: 3591 KDVHEEDKAVAFSDLSSADQNFEQVNLSGQTECFEVENLNKHADASTTTHQVIEDP---- 3424
+D+ E+D V S+ S + N + T E N K + + Q+ ED
Sbjct: 2244 EDILEKDLNVDNSEGRSNEYNTIHMQNKADTILDEHNNREKIDNNGKISEQISEDKSYNL 2303
Query: 3423 -VKEESDVLSQDRVH------------------EEDGDNPKDEEDNVESFEMSKGQEPAI 3301
+K E D L D ++ +E+ D KDE D + K +E I
Sbjct: 2304 DIKVERDALPHDSINIQKAKDEADIKKEEADIKKEEADIKKDEADIKKDEADIKKEETDI 2363
Query: 3300 SHQEKTIAEATTLIQKSETESMKLNRTGEPDSTEV 3196
+E I + T IQK E +K + T++
Sbjct: 2364 QKEEADIKKEETDIQKEEEAVIKKDEADIKKETDI 2398
Score = 145 bits (365), Expect = 2e-31
Identities = 274/1146 (23%), Positives = 447/1146 (39%), Gaps = 72/1146 (6%)
Frame = -3
Query: 6453 VIEGLENVDLDKDIGEPITEKDVAPDHSITAFEEEPI--KYVHEEDKVIEGTEIIGADKD 6280
+IE +D +K + E +++ + T E P+ + +E K +E T+ + +
Sbjct: 647 IIESHSTLDENKTV-----EGNISTHETKTVEEGIPVHESKIVDEHKPLEETKKVEEYEP 701
Query: 6279 IGDPIIGEEIVPDHSTTTIRGE-PIQDDH--EEDKVTEELKIDGANKDIGEP-SIKDVVL 6112
+ + E +P + + T+ G P ++ EED E K +K + E +++ +
Sbjct: 702 VHESKTVEGNIPKYESKTVEGNIPAYENKTIEEDMPVNETKTIEEHKPVHETKTVEQSIP 761
Query: 6111 DQSTSSIGET-PAKDGHEEHKLVGADKDIGKTIIKENVIPDHPIKTIGEIKHDHEEDKVI 5935
T +I E PA E K+V DK + +T E IP H KT+ E K HE V
Sbjct: 762 VHETKAIEENIPAY----ESKIVEEDKPVHETKTVEENIPVHETKTVEEDKPVHETKTVE 817
Query: 5934 EGLDIDCGNEDNGEPITEEDGVRGHSTKTTWEEPAKDGHEEKVT---KGLE---IVDTNK 5773
E + E T E+ + + TKT E K HE KV K LE ++ +K
Sbjct: 818 EDKPV-------YETKTIEEDIPVYETKTV--EEHKPVHESKVIDEHKPLEETKTIEEHK 868
Query: 5772 NCGKPFIEDDVIPEHSTTITGEKAIRNGQ--EEDKVIEELEKVDAEENIGEPIIEKDVVP 5599
+ + I ++ IP H T +K + + +E K EE + VD E ++ +P
Sbjct: 869 STYESQIVEENIPVHETKTVEDKPVYESKVIDEHKPFEETKTVDDNMPTYETKAIEENMP 928
Query: 5598 DHATTLGEELINDVHDDDKVIEGFEIVGSDKDTGEPVIVEDVVPEHPTTTSGKESIKDGH 5419
H T + EE DK + + + D E IVE+ +P H T T +E+I
Sbjct: 929 VHETKIVEE--------DKPVHETKAIEEDIPVHETKIVEN-IPVHETKTI-EENI---- 974
Query: 5418 XXXXXXXXXXXVGADREIREPVIEEDIVPDLSTTTREEPIEDGHEKNKVIEGL-EIASSD 5242
V + + E E+ P T T E+ I HE + E + S
Sbjct: 975 ----PAYETKTVEENIPVHETKTVEEDKPVYETKTVEQSI-PVHETKAIEENIPAYESKT 1029
Query: 5241 KENGDPI-----IEEVVPDHSTTTIGKESTNDVHE-----EDKVVAGLDIVGVDKDIGEP 5092
E P+ IEE +P + T T+ E VHE E K + + K E
Sbjct: 1030 VEEDKPVYETKTIEEDMPVYETKTV--EEHKPVHESRVIDEHKPLEETKTIEEHKSPYES 1087
Query: 5091 VIKDDVVPDRSTTTIEEEPIQDGQAENEVIEGLEKVELDKDFGDPITEKDVAPDYSITTF 4912
I ++ +P T T+E++P+ + + +E K F + T D P Y
Sbjct: 1088 QIVEENIPVHETKTVEDKPVYESKVIDE----------HKPFEETKTLDDNMPTYESKVI 1137
Query: 4911 DE----ETIKDVHEEDKVIEGAEIGGDNDIGDPVIGEEVVPDNSTTTIRGEPIQDDHEED 4744
DE E K V + E I + + + I EE P + T I EED
Sbjct: 1138 DEHKPFEETKTVDDNMPTYETKAIEENMPVHETKIVEEDKPVHETKAI---------EED 1188
Query: 4743 KMRERLKIDGANKDIVEPTVKDVVLDQSTTTIGETPVKDGHGGHKVTAGLERVGADKDIG 4564
KI V+++ + ++ T + P T + V DK +
Sbjct: 1189 IPVHETKI-----------VENIPVHETKTIEEDIP----------TYETKTVEEDKPVH 1227
Query: 4563 EPITKENVVSDHPIKTIGDIKDDHEEDKVIEGLDIGGNEDIGE--PT-----IEDGISYH 4405
E T E+ + H KT+ + K HE V + + + + + + PT IE+ I H
Sbjct: 1228 ETKTVEDNIPVHETKTVEEDKPVHETKTVEDNIPVHETKTVEDNIPTYETKGIEENIPVH 1287
Query: 4404 STTTTWEEPTKDGHEEKVTEGLEIVDTDENSGNHFIEDDVSEHSTTITGEEAIQNGQEED 4225
T T E+ K HE K E E + +E+ +ED + + T+ E+
Sbjct: 1288 ETKTVEED--KPVHETKAIE--EDIPVNESK---IVEDMPTYETKTV-----------EN 1329
Query: 4224 KMIEGLEKVDADKDIGEPIIEKDGPDHSTTLGAELINDVHDEDKVNEGL-----ERVGSD 4060
+ +K++ K E + +D P + T E I ++ VN+ + + + D
Sbjct: 1330 IPVNETKKIEEHKPAYESKLVEDMPTYETKAIEEDI-PTYETKTVNDNMPIYETKTLEED 1388
Query: 4059 KDTGEPVIVEDVVPDNSTRASGEKPIQDGHG--------EEKITERLEIDRTDKEIGEPT 3904
E IVED+ + KP+ + E KI E + T T
Sbjct: 1389 IPVHETKIVEDMPTYETKTIDEHKPLDETKTIEEHKPAYESKIVEDMPTYET------KT 1442
Query: 3903 MEEGVVLDQSTTIGVEPVVDNYK---EHKVTEGLEIIGENKDIGEPIIEENLVLDHSTTP 3733
+EE L ++ TI +D K EHK T +I+ E+K E E + H T
Sbjct: 1443 VEEDKPLHETKTIDEHKPLDETKTIEEHKSTHESQIVEEDKPAYETKTVEQSIPVHETKA 1502
Query: 3732 IVEIKDGHEEDKVIEGSELAGAEDIGE--PI-----TEEDVSDHTTTTIGKE----PTKD 3586
I E +E V E + + + E P+ E+ + H T I + +K
Sbjct: 1503 IEENIPAYETKTVEENIPVHETKTVEEDKPVYETKTVEQSIPVHETKAIEENIPAYESKT 1562
Query: 3585 VHEEDKAVAFSDLSSADQNFEQVNLSGQTECFEVENLNKHADASTTTHQVIEDPVKEESD 3406
V EEDK S + +E + E + + + + T V ED ES
Sbjct: 1563 V-EEDKPAYESKIVEDMPTYETKTVEEDKPVHETKTVEEDI-PTYETKTVEEDKPVYESK 1620
Query: 3405 VLSQD-RVHEE---DGDNP----KDEEDNVESFEMSKGQEPAISHQEKTIAEATTLIQKS 3250
V+ +D VHE + D P K E+++ ++E +E ++ K I E + +
Sbjct: 1621 VIEEDIPVHETKTVEEDKPVYETKIVEEDIPTYETKTVEEDKPVYESKVIEENIPVHETK 1680
Query: 3249 ETESMK 3232
E K
Sbjct: 1681 TVEEDK 1686
Score = 92.0 bits (227), Expect = 2e-15
Identities = 200/902 (22%), Positives = 352/902 (39%), Gaps = 58/902 (6%)
Frame = -3
Query: 5763 KPFIEDDVIPEHSTTITG-------EKAIRNGQEEDKVIEEL----EKVDAEENIGEPII 5617
KPF+ D+ I E T ++ R+ E K+I++L E+ + ++ I +I
Sbjct: 280 KPFVADNEIVERYVECTDLPPCTEEQRKSRDKYEYKKIIKDLNDEAEQKEYQDTIERKVI 339
Query: 5616 EKDVVPDHATTLGEELINDVHD--DDKVIE--------------GF--EIVGSDKDTGEP 5491
EK + I +H+ D+++ G+ E G+ +D +
Sbjct: 340 EKIREGETEAQANARKIKAIHEFIDNRINAMLNKQYALLNIKPPGYKEETKGNSEDLTDT 399
Query: 5490 VIVEDVVPEHPTTTSGKESIKDGHXXXXXXXXXXXVGADREIREPVIEEDIVPDLSTTTR 5311
I+ +++P T SG ++K ++ +E + E+ P +
Sbjct: 400 NIISEILPPQ-YTVSGNSNLKKYPAKDTDSKKGDNHEPHKDDQEIKVIENYHPKQNGEVE 458
Query: 5310 EEPIEDGHEKN----------KVIEGLEIASSDKENGDPIIEEVVPDHSTTTIGKESTND 5161
+E E ++ + +++E ++ ++K DPI D
Sbjct: 459 KEISEINNDSDGNITKNPTDIRILEKKQLNGNNKHTDDPI-------------DGAQDGD 505
Query: 5160 VHEEDKVVAGLDIVGVDKDIGEPVIKDDVVPDRSTTTIEEEPIQ---DGQAENEVIEGLE 4990
+E + + +I G+DK+ E I +++ D +T+ ++ +PI D + N E
Sbjct: 506 KYEGNVIAENKEIKGIDKNTDETTINNNMRVD-NTSEMKADPIYTSVDHEKNNGNAES-N 563
Query: 4989 KVELDKDFGDPITEKDVAPDYSITTFDEETIKDVHEEDK-VIEGAEIGGDNDIGDPVIGE 4813
K L K+ + + K+ D I F ++T + ++DK ++ E+ G+
Sbjct: 564 KQTLPKEESE--SNKEKYEDKQI--FPDKTKSETEKKDKEIVTDQELNKITQNGNVENKG 619
Query: 4812 EVVPDNSTTTIRGEPIQDDHEEDKMRERLKIDGANKDIVEPTVKDVVLDQSTTTIGETPV 4633
E P+NS T + I + +++ ID N I+E S +T+ E
Sbjct: 620 EENPENSKTIVSDSNI--------LSKQIPID--NTKIIE----------SHSTLDENKT 659
Query: 4632 KDGHGGHKVTAGLERVGADKDIGEPITKENVVSDHPIKTIGDIKDDHEEDKVIEGLDIGG 4453
+G+ T +E G P+ + +V +H K + + K E + V E + G
Sbjct: 660 VEGNISTHETKTVEE-------GIPVHESKIVDEH--KPLEETKKVEEYEPVHESKTVEG 710
Query: 4452 NEDIGEPTIEDGISYHSTTTTWEEPTKDGHEEKVTEGLEIVDTDENSGNHFIEDDVSEHS 4273
N Y S T P + + + E + + +T IE+ H
Sbjct: 711 NIP----------KYESKTVEGNIPAYEN--KTIEEDMPVNETKT------IEEHKPVHE 752
Query: 4272 TTITGEEAIQNGQEEDKMIEGLEKVDADKDIGEPIIEKDGPDHSTTLGAELINDVHD--- 4102
T T E++I E K IE E + A + I+E+D P H T E I VH+
Sbjct: 753 TK-TVEQSIP--VHETKAIE--ENIPAYES---KIVEEDKPVHETKTVEENI-PVHETKT 803
Query: 4101 --EDKVNEGLERVGSDKDTGEPVIVEDVVPDNSTRASGE-KPIQ-----DGHGEEKITER 3946
EDK + V DK E +E+ +P T+ E KP+ D H + T+
Sbjct: 804 VEEDKPVHETKTVEEDKPVYETKTIEEDIPVYETKTVEEHKPVHESKVIDEHKPLEETKT 863
Query: 3945 LEIDRTDKEIGEPTMEEGVVLDQSTTIGVEPVVDN--YKEHKVTEGLEIIGENKDIGEP- 3775
+E ++ E +EE + + ++ T+ +PV ++ EHK E + + +N E
Sbjct: 864 IEEHKSTYE--SQIVEENIPVHETKTVEDKPVYESKVIDEHKPFEETKTVDDNMPTYETK 921
Query: 3774 IIEENLVLDHSTTPIVEIKDGHEEDKVIEGSELAGAEDIGEPITEEDVSDHTTTTIGKEP 3595
IEEN+ + H T + E K HE + EED+ H T + P
Sbjct: 922 AIEENMPV-HETKIVEEDKPVHETKAI-----------------EEDIPVHETKIVENIP 963
Query: 3594 TKDVHEEDKAVAFSDLSSADQNFEQVNLSGQTECFEVENLNKHADASTTTHQVIED-PVK 3418
VHE + E+ + +T+ E EN+ H T V ED PV
Sbjct: 964 ---VHET-------------KTIEENIPAYETKTVE-ENIPVHE-----TKTVEEDKPVY 1001
Query: 3417 EESDVLSQDRVHEEDGDNPKDEEDNVESFEMSKGQEPAISHQEKTIAEATTLIQKSETES 3238
E V VHE K E+N+ ++E +E ++ KTI E + + E
Sbjct: 1002 ETKTVEQSIPVHET-----KAIEENIPAYESKTVEEDKPVYETKTIEEDMPVYETKTVEE 1056
Query: 3237 MK 3232
K
Sbjct: 1057 HK 1058
Score = 84.7 bits (208), Expect = 3e-13
Identities = 173/772 (22%), Positives = 297/772 (38%), Gaps = 52/772 (6%)
Frame = -3
Query: 5379 ADREIREPVIEEDIVPDLSTTTREEPIEDGHEKNKVIEGLEIASSDKENGDPI----IEE 5212
AD EI E +E +P + R+ D +E K+I+ L + KE D I IE+
Sbjct: 284 ADNEIVERYVECTDLPPCTEEQRKS--RDKYEYKKIIKDLNDEAEQKEYQDTIERKVIEK 341
Query: 5211 VVPDHSTTTIGKESTNDVHE--EDKVVAGLDIVGVDKDIGEPVIKDDVV---PDRSTTTI 5047
+ + +HE ++++ A L+ +I P K++ D + T I
Sbjct: 342 IREGETEAQANARKIKAIHEFIDNRINAMLNKQYALLNIKPPGYKEETKGNSEDLTDTNI 401
Query: 5046 EEE--PIQDGQAENEVIEGLEKVELDKDFGDPITEKDVAPDYSITTFDEETIKDVHEEDK 4873
E P Q + N ++ + D GD + D I + K E +K
Sbjct: 402 ISEILPPQYTVSGNSNLKKYPAKDTDSKKGD--NHEPHKDDQEIKVIENYHPKQNGEVEK 459
Query: 4872 VIEGAEIGGDND---IGDP----VIGEEVVPDNSTTT---IRGEPIQDDHEEDKMRERLK 4723
I +EI D+D +P ++ ++ + N+ T I G D +E + + E +
Sbjct: 460 EI--SEINNDSDGNITKNPTDIRILEKKQLNGNNKHTDDPIDGAQDGDKYEGNVIAENKE 517
Query: 4722 IDGANKDIVEPTVKDVVLDQSTTTIGETPVKDGHGGHKVTAGLERVGADKDIGEPITKEN 4543
I G +K+ E T+ + + +T+ + P+ K E E + +
Sbjct: 518 IKGIDKNTDETTINNNMRVDNTSEMKADPIYTSVDHEKNNGNAESNKQTLPKEESESNKE 577
Query: 4542 VVSDHPI----------KTIGDIKDDHEEDKVIEGLDIGGNEDIGEPTIEDGISYHSTTT 4393
D I K +I D E +K+ + G E+ GE E+ + S +
Sbjct: 578 KYEDKQIFPDKTKSETEKKDKEIVTDQELNKITQN---GNVENKGEENPENSKTIVSDSN 634
Query: 4392 TWEEPTKDGHEEKVTEGLEIVDTDENSGNHFIEDDVSEHSTTITGEEAIQNGQ------- 4234
+ + K+ E +D N +E ++S H T T EE I +
Sbjct: 635 ILSKQIPIDNT-KIIESHSTLDE-----NKTVEGNISTHETK-TVEEGIPVHESKIVDEH 687
Query: 4233 ---EEDKMIEGLEKVDADKDIGEPIIEKDGPDHSTTLGAELINDVHDEDKVNEGLERVGS 4063
EE K +E E V K + I + + + A + ++ VNE + +
Sbjct: 688 KPLEETKKVEEYEPVHESKTVEGNIPKYESKTVEGNIPAYENKTIEEDMPVNE-TKTIEE 746
Query: 4062 DKDTGEPVIVEDVVPDNSTRASGEK-PIQDGHGEEKITERLEIDRTDKEIGEP-TMEEGV 3889
K E VE +P + T+A E P E KI E DK + E T+EE +
Sbjct: 747 HKPVHETKTVEQSIPVHETKAIEENIPAY----ESKIVEE------DKPVHETKTVEENI 796
Query: 3888 VLDQSTTIGVEPVVDNYKEHKVTEGLEIIGENKDIGE--PIIEENLVLDHSTTPIVEIKD 3715
+ ++ T+ + V E K E + + E K I E P+ E V +H ++ D
Sbjct: 797 PVHETKTVEEDKPVH---ETKTVEEDKPVYETKTIEEDIPVYETKTVEEHKPVHESKVID 853
Query: 3714 GH---EEDKVIEGSELAGAEDIGEPITEEDVSDHTTTTIGKEPTKDVHEEDKAVAFSDLS 3544
H EE K IE + I EE++ H T T+ +P + D+ F +
Sbjct: 854 EHKPLEETKTIEEHK----STYESQIVEENIPVHETKTVEDKPVYESKVIDEHKPFEETK 909
Query: 3543 SADQNFEQVNLSGQTECFEVENLNKHADASTTTHQ---VIEDPVKEESDVLSQDRVHEED 3373
+ D N E V K + H+ + ED E+ ++ VHE
Sbjct: 910 TVDDNMPTYETKAIEENMPVHE-TKIVEEDKPVHETKAIEEDIPVHETKIVENIPVHET- 967
Query: 3372 GDNPKDEEDNVESFEMSKGQEPAISHQEKTIAEATTLIQ-KSETESMKLNRT 3220
K E+N+ ++E +E H+ KT+ E + + K+ +S+ ++ T
Sbjct: 968 ----KTIEENIPAYETKTVEENIPVHETKTVEEDKPVYETKTVEQSIPVHET 1015
Score = 73.2 bits (178), Expect = 9e-10
Identities = 109/492 (22%), Positives = 213/492 (43%), Gaps = 58/492 (11%)
Frame = -1
Query: 2921 EEQVIKEIPEKTESANHETIFVTQPTEKLSLHEAEPQGGELVDASD--DASVEMFSTPI- 2751
E ++EI ES +TI +P E+ E E + + +DASD D + + I
Sbjct: 2061 ENNTVEEIIPVHES---KTIKEHKPLEETKTIE-EHKPVDTIDASDIIDKGISIDDNKII 2116
Query: 2750 EEHGASSLDPD--MEDVKQGEIATLDDNATDNTFTAENAETEHEKPEVPVENSAVATQSV 2577
+E+G D D +E++ G +T N +DN+ + E E+ VP +N +T ++
Sbjct: 2117 QENGGRISDKDEAIENL-DGYESTKSTNYSDNS-----DDNEEEEIIVPNQNIDSSTSNI 2170
Query: 2576 DKDTQTTLVSEITASKASSDDLSEE---KPQKSSMLISAKNEFNAV----------GMKE 2436
D + + + +K + D E + +K + ++N + V G+
Sbjct: 2171 INDQSKIIYTGKSVNKTLNSDSDENMHMESRKEDIQKESENNKDVVSHIPDDKIIHGVVN 2230
Query: 2435 KIKEECQIDDEIKDKKMEAPL-VAQTKGEVNMQTEEHLNLEKDSEMGIENTEQKISVXXX 2259
+++ ID++ + +E L V ++G N H+ + D+ + N +KI
Sbjct: 2231 NDEKKLLIDEKNIEDILEKDLNVDNSEGRSNEYNTIHMQNKADTILDEHNNREKIDNNGK 2290
Query: 2258 XXXXXXXEQK-DADVSLEREKI----IELNEYKENNRSETSDSGLKETKFE--------S 2118
++ + D+ +ER+ + I + + K+ + ++ +K+ + +
Sbjct: 2291 ISEQISEDKSYNLDIKVERDALPHDSINIQKAKDEADIKKEEADIKKEEADIKKDEADIK 2350
Query: 2117 EEEFDACSKELETTGTCANI---ETDILEQEEDALKKLDQNLESEKGTMKVEEIQVEV-- 1953
++E D +E + A+I ETDI ++EE +KK + +++ E K +I+ E
Sbjct: 2351 KDEADIKKEETDIQKEEADIKKEETDIQKEEEAVIKKDEADIKKETDIKKETDIKKETDI 2410
Query: 1952 ---KATDHSHKINESHNTAESALLAQDN-------LEAIDPCDEIKRDT----EST---- 1827
+A I+ + E L+ +DN + + CDE R++ EST
Sbjct: 2411 KKDEAVIKKEDISMNKEIDEKKLIIEDNTNCPPNVITIKEKCDETARESDVNPESTIIKD 2470
Query: 1826 --DHDQSKEALSEIEKTEVVEDKEIMKYQNVV-SVEDHTVGESIQDEENENDSLDEAGPK 1656
D +IEKTE E E + +V+ +D + E I D N+N + +E G K
Sbjct: 2471 KDDVSTENSNTEKIEKTEKTEKTEKTEKNDVIDDSDDFNINEIISDVVNDNVNSNENGNK 2530
Query: 1655 LNANDQNDDMND 1620
+ N++ ++D
Sbjct: 2531 YDQNEKLGMLDD 2542
Score = 66.2 bits (160), Expect = 1e-07
Identities = 184/931 (19%), Positives = 348/931 (37%), Gaps = 74/931 (7%)
Frame = -1
Query: 3059 EIVTLEEETPKNSLNDFRATEAPLEEITKMKKSDKLNY-TPTESAMSEEQVIKEIPEKTE 2883
E T+EE+ P + + P+ E TK + DK Y T T K I E
Sbjct: 1678 ETKTVEEDKPVHETKAIEE-DIPVHE-TKTVEEDKPVYETKTVDDNMPTYETKGIEENMP 1735
Query: 2882 SANHETIFVTQP-----TEKLSLHEAEPQGGELVDASDDASVEMFSTPIEEHGASSLDPD 2718
HET V + T+ + H+ + + D + I H +++
Sbjct: 1736 V--HETKIVEEDKPLEETKTIEEHKPTYETKTVDDNMPTYETKGIEENIPVHETKTIE-- 1791
Query: 2717 MEDVKQGEIATLDDNATDNTFTAENAETEHEKP---------EVPVENSAVATQSVDKDT 2565
ED+ E T++DN E+ E +KP +PV + + DK
Sbjct: 1792 -EDIPTYETKTVNDNMP----IYESKTVEEDKPTYETKGIEENIPVHETKTVEE--DKPV 1844
Query: 2564 QTTLVSEITASKASSDDLSEEKPQKSSMLISAKNEFNAVGMKEKIKEECQIDDEIKDKKM 2385
T E S + E+KP + I + KI EE + +E K +
Sbjct: 1845 HETKAIEEDIPAYESKIVEEDKPVYETKTIDEDKPV----YETKIVEEYKPLEETKTIEE 1900
Query: 2384 EAPLVAQTKGEVNMQTEEHLNLEKDSEMGIENTEQKISVXXXXXXXXXXEQKDADVSLER 2205
P +TK +M T E L++ + E KI + D+ +
Sbjct: 1901 HKPTY-ETKIVEDMPTYETKTLDEHKHVH----ESKIV--------------EDDIPVHE 1941
Query: 2204 EKIIELNEYKENNRSETSDSGLKETKFESEEEFDACSKELETTGTC---ANIETDILEQE 2034
K+IE ++ + N+ D + ETK E+ +K +E +E DI E
Sbjct: 1942 TKVIEEHKPLDENKVIEEDIPVYETKTVEEDNPTYETKTVEENIPVYENKTVEEDIPVHE 2001
Query: 2033 EDAL---------KKLDQNLESEKGTMKVEEIQV-EVKATDHSHKINESHNTAESALLAQ 1884
+ K +D++ E+ E+I + E K D ++E+ E + +
Sbjct: 2002 TKTIEEVIPTYENKVIDEHKPFEETKTIEEDISLDENKVIDEVIPLHETKTVEEGIPVHE 2061
Query: 1883 DN-LEAIDPCDEIKRDTESTDHDQSKEALSEIEKTEVVEDKEIMKYQNVVSVEDHTV--- 1716
+N +E I P E K E +++K + E + + ++ +I+ +S++D+ +
Sbjct: 2062 NNTVEEIIPVHESKTIKEHKPLEETK-TIEEHKPVDTIDASDII--DKGISIDDNKIIQE 2118
Query: 1715 -GESIQDEENENDSLD--EAGPKLNANDQNDDMNDVNPPIKDAIVNEEMPHGVERADNGR 1545
G I D++ ++LD E+ N +D +DD + EE+ + D+
Sbjct: 2119 NGGRISDKDEAIENLDGYESTKSTNYSDNSDDNEE-----------EEIIVPNQNIDSST 2167
Query: 1544 EETLVGEVGEQCKVDPNFESDLQNEGADKGNDEEDKCRKLDAXXXXXXXXXXXXXXVGKQ 1365
+ +Q K+ +S + +D + + RK D K+
Sbjct: 2168 SNI----INDQSKIIYTGKSVNKTLNSDSDENMHMESRKEDIQ---------------KE 2208
Query: 1364 LEEESDLV---PGELINEIVTNRTEN----EGGAPKDTTDTDGVIDVNKPAESTFST--- 1215
E D+V P + I V N E + +D + D +D ++ + ++T
Sbjct: 2209 SENNKDVVSHIPDDKIIHGVVNNDEKKLLIDEKNIEDILEKDLNVDNSEGRSNEYNTIHM 2268
Query: 1214 -NTTSTIEKLHIDEKLLTDNPDASSLTEASQESMQEKEGKNTEDGEKQEVVFVKKATKDM 1038
N TI H + + + +N S + S++ + K D + + ++KA +
Sbjct: 2269 QNKADTILDEHNNREKIDNNGKISE--QISEDKSYNLDIKVERDALPHDSINIQKAKDEA 2326
Query: 1037 GLPTEES---RENIEHEAPVAEMSKEGG---KKINEVSIEEKSFRNEEGETQVLKQPDTP 876
+ EE+ +E + + A++ K+ K+ ++ EE + EE + Q ++
Sbjct: 2327 DIKKEEADIKKEEADIKKDEADIKKDEADIKKEETDIQKEEADIKKEETDIQKEEEAVIK 2386
Query: 875 RDLQMLDQSSDVTAE----QEASIETDSIEKTKENISIG------------SIEIPSAPV 744
+D + + +D+ E +E I+ D KE+IS+ + P +
Sbjct: 2387 KDEADIKKETDIKKETDIKKETDIKKDEAVIKKEDISMNKEIDEKKLIIEDNTNCPPNVI 2446
Query: 743 DVIEKSLQTA-EVEEGKHGEVQGNDSELNTVECEASFDEETNTNSKSSEAKGASLFD--- 576
+ EK +TA E + + + +++T E+T K+ + + + D
Sbjct: 2447 TIKEKCDETARESDVNPESTIIKDKDDVSTENSNTEKIEKTEKTEKTEKTEKNDVIDDSD 2506
Query: 575 --LLNKPRKDTGQAVEQFEEEGNSTSNKEQL 489
+N+ D E GN E+L
Sbjct: 2507 DFNINEIISDVVNDNVNSNENGNKYDQNEKL 2537
>ref|XP_725378.1| hypothetical protein [Plasmodium yoelii yoelii 17XNL]
gi|23480363|gb|EAA16943.1| 250-270 copies of a 13 AA
repeat, NSSTPITSSSIL [Plasmodium yoelii yoelii]
Length = 2689
Score = 157 bits (396), Expect = 5e-35
Identities = 288/1235 (23%), Positives = 467/1235 (37%), Gaps = 154/1235 (12%)
Frame = -3
Query: 6438 ENVDLDKDIGEPITEKDVAPDHSITAFEEEPIKYVHEEDKVIEGTEIIGADKDIGDPIIG 6259
+ V+ DK + E T +D P H EE+ K VHE K +E + K + D I
Sbjct: 1187 KTVEEDKPVHETKTVEDNIPVHETKTVEED--KPVHET-KTVEDNIPVHETKTVEDNIPT 1243
Query: 6258 ------EEIVPDHSTTTIRGEPIQDDHEEDKVTEELKIDGANKDIGEPSIKDVVLDQSTS 6097
EE +P H T T+ EEDK E K + + E I + + T
Sbjct: 1244 YETKGIEENIPVHETKTV---------EEDKPVHETKAIEEDIPVNESKIVEDMPTYETK 1294
Query: 6096 SIGETPAKDGH--EEHKLVGADKDIG-----KTIIKENVIPDHPIKTIGEIKHDHEEDKV 5938
++ P + EEHK K + +T E IP + KT+ + +E +
Sbjct: 1295 TVENIPVNETKKIEEHKPAYESKLVEDMPTYETKAIEEDIPTYETKTVNDNMPIYETKTL 1354
Query: 5937 IEGLDIDCGNEDNGEPITEEDGVRGHST--KTTWEEPAKDGHEEKVTKGLEIVDTNK-NC 5767
E + + P E + H +T E K +E K+ + + +T
Sbjct: 1355 EEDIPVHETKIVEDMPTYETKTIDEHKPLDETKTIEEHKPAYESKIVEDMPTYETKTVEE 1414
Query: 5766 GKPFIEDDVIPEH-----STTITGEKAIRNGQ--EEDKVIEELEKVDAEENIGEPIIEKD 5608
KP E I EH + TI K+ Q EEDK E + V+ + E ++
Sbjct: 1415 DKPLHETKTIDEHKPLDETKTIEEHKSTHESQIVEEDKPAYETKTVEQSIPVHETKAIEE 1474
Query: 5607 VVPDHATTLGEELINDVHDDDKVIEGFEIVGSDKDTGEPVIVEDVVPEHPTTTSGKESIK 5428
+P + T EE I VH+ V E DK E VE +P H T +E+I
Sbjct: 1475 NIPAYETKTVEENI-PVHETKTVEE-------DKPVYETKTVEQSIPVHETKAI-EENIP 1525
Query: 5427 DGHXXXXXXXXXXXVGADREIREPVIEEDIVPDLSTTTREEPIEDG--HEKNKVIEGLEI 5254
E +P E IV D+ T + ED HE V E +
Sbjct: 1526 ------------AYESKTVEEDKPAYESKIVEDMPTYETKTVEEDKPVHETKTVEEDIPT 1573
Query: 5253 ASSDKENGDP------IIEEVVPDHSTTTIGKEST---NDVHEEDKVVAGLDIVGVDKDI 5101
+ D +IEE +P H T T+ ++ + EED V DK +
Sbjct: 1574 YETKTVEEDKPVYESKVIEEDIPVHETKTVEEDKPVYETKIVEEDIPTYETKTVEEDKPV 1633
Query: 5100 GEPVIKDDVVPDRSTTTIEEE-PIQDGQA--ENEVIEGLEKVELDKDFGDPITEKDVAPD 4930
E + ++ +P T T+EE+ P+ + +A E+ + + VE DK + T D P
Sbjct: 1634 YESKVIEENIPVHETKTVEEDKPVHETKAIEEDIPVHETKTVEEDKPVYETKTVDDNMPT 1693
Query: 4929 YSITTFDEETIKDVHEEDKVIEGAEIGGDNDIGDPVIGEEVVPDNSTTTIRGEPIQDDHE 4750
Y +E VHE K++E D + + EE P T T+ + +E
Sbjct: 1694 YETKGIEENM--PVHET-KIVEE-----DKPLEETKTIEEHKPTYETKTV--DDNMPTYE 1743
Query: 4749 EDKMRERLKIDGANKDIVEPTVKDVVLDQSTTTIGET-PVKDGHGGHKVTAGLERVGADK 4573
+ E + + T+++ + T T+ + P+ + + E G ++
Sbjct: 1744 TKGIEENIPVHETK------TIEEDIPTYETKTVNDNMPIYESKTVEEDKPTYETKGIEE 1797
Query: 4572 DIGEPITKENVVSDHPIKTIGDIKDDH--------EEDK-VIEGLDIGGNEDIGEPTIED 4420
+I TK V D P+ I++D EEDK V E I ++ + E I +
Sbjct: 1798 NIPVHETK-TVEEDKPVHETKAIEEDIPAYESKIVEEDKPVYETKTIDEDKPVYETKIVE 1856
Query: 4419 GISYHSTTTTWEEPTKDGHEEKVTEGLEIVDT---DENSGNH---FIEDDVSEHSTTITG 4258
T T EE K +E K+ E + +T DE+ H +EDD+ H T +
Sbjct: 1857 EYKPLEETKTIEEH-KPTYETKIVEDMPTYETKTLDEHKHVHESKIVEDDIPVHETKVIE 1915
Query: 4257 EEAIQNGQ---EEDKMIEGLEKVDAD------KDIGEPI-------IEKDGPDHSTTLGA 4126
E + EED + + V+ D K + E I +E+D P H T
Sbjct: 1916 EHKPLDENKVIEEDIPVYETKTVEEDNPTYETKTVEENIPVYENKTVEEDIPVHETKTIE 1975
Query: 4125 ELI----NDVHDEDKVNEGLERVGSDKDTGEPVIVEDVVPDNSTRASGEK-PIQDG---- 3973
E+I N V DE K E + + D E ++++V+P + T+ E P+ +
Sbjct: 1976 EVIPTYENKVIDEHKPFEETKTIEEDISLDENKVIDEVIPLHETKTVEEGIPVHENNTVE 2035
Query: 3972 -----HGEEKITERLEIDRTDKEIGE----PTMEEGVVLDQSTTIGVEPVV--------- 3847
H + I E ++ T K I E T++ ++D+ +I ++
Sbjct: 2036 EIIPVHESKTIKEHKPLEET-KTIEEHKPVDTIDASDIIDKGISIDDNKIIQENGGRISD 2094
Query: 3846 --------DNYKEHKVTEGLEIIGENKDIGEPIIEENLVLDHSTTPIVE-----IKDGHE 3706
D Y+ K T + +N++ E II N +D ST+ I+ I G
Sbjct: 2095 KDEAIENLDGYESTKSTNYSDNSDDNEE--EEIIVPNQNIDSSTSNIINDQSKIIYTGKS 2152
Query: 3705 EDKVIEGS----------------ELAGAEDIGEPITEEDV------SDHTTTTIGKEPT 3592
+K + E +D+ I ++ + +D I ++
Sbjct: 2153 VNKTLNSDSDENMHMESRKEDIQKESENNKDVVSHIPDDKIIHGVVNNDEKKLLIDEKNI 2212
Query: 3591 KDVHEEDKAVAFSDLSSADQNFEQVNLSGQTECFEVENLNKHADASTTTHQVIEDP---- 3424
+D+ E+D V S+ S + N + T E N K + + Q+ ED
Sbjct: 2213 EDILEKDLNVDNSEGRSNEYNTIHMQNKADTILDEHNNREKIDNNGKISEQISEDKSYNL 2272
Query: 3423 -VKEESDVLSQDRVH------------------EEDGDNPKDEEDNVESFEMSKGQEPAI 3301
+K E D L D ++ +E+ D KDE D + K +E I
Sbjct: 2273 DIKVERDALPHDSINIQKAKDEADIKKEEADIKKEEADIKKDEADIKKDEADIKKEETDI 2332
Query: 3300 SHQEKTIAEATTLIQKSETESMKLNRTGEPDSTEV 3196
+E I + T IQK E +K + T++
Sbjct: 2333 QKEEADIKKEETDIQKEEEAVIKKDEADIKKETDI 2367
Score = 145 bits (365), Expect = 2e-31
Identities = 274/1146 (23%), Positives = 447/1146 (39%), Gaps = 72/1146 (6%)
Frame = -3
Query: 6453 VIEGLENVDLDKDIGEPITEKDVAPDHSITAFEEEPI--KYVHEEDKVIEGTEIIGADKD 6280
+IE +D +K + E +++ + T E P+ + +E K +E T+ + +
Sbjct: 616 IIESHSTLDENKTV-----EGNISTHETKTVEEGIPVHESKIVDEHKPLEETKKVEEYEP 670
Query: 6279 IGDPIIGEEIVPDHSTTTIRGE-PIQDDH--EEDKVTEELKIDGANKDIGEP-SIKDVVL 6112
+ + E +P + + T+ G P ++ EED E K +K + E +++ +
Sbjct: 671 VHESKTVEGNIPKYESKTVEGNIPAYENKTIEEDMPVNETKTIEEHKPVHETKTVEQSIP 730
Query: 6111 DQSTSSIGET-PAKDGHEEHKLVGADKDIGKTIIKENVIPDHPIKTIGEIKHDHEEDKVI 5935
T +I E PA E K+V DK + +T E IP H KT+ E K HE V
Sbjct: 731 VHETKAIEENIPAY----ESKIVEEDKPVHETKTVEENIPVHETKTVEEDKPVHETKTVE 786
Query: 5934 EGLDIDCGNEDNGEPITEEDGVRGHSTKTTWEEPAKDGHEEKVT---KGLE---IVDTNK 5773
E + E T E+ + + TKT E K HE KV K LE ++ +K
Sbjct: 787 EDKPV-------YETKTIEEDIPVYETKTV--EEHKPVHESKVIDEHKPLEETKTIEEHK 837
Query: 5772 NCGKPFIEDDVIPEHSTTITGEKAIRNGQ--EEDKVIEELEKVDAEENIGEPIIEKDVVP 5599
+ + I ++ IP H T +K + + +E K EE + VD E ++ +P
Sbjct: 838 STYESQIVEENIPVHETKTVEDKPVYESKVIDEHKPFEETKTVDDNMPTYETKAIEENMP 897
Query: 5598 DHATTLGEELINDVHDDDKVIEGFEIVGSDKDTGEPVIVEDVVPEHPTTTSGKESIKDGH 5419
H T + EE DK + + + D E IVE+ +P H T T +E+I
Sbjct: 898 VHETKIVEE--------DKPVHETKAIEEDIPVHETKIVEN-IPVHETKTI-EENI---- 943
Query: 5418 XXXXXXXXXXXVGADREIREPVIEEDIVPDLSTTTREEPIEDGHEKNKVIEGL-EIASSD 5242
V + + E E+ P T T E+ I HE + E + S
Sbjct: 944 ----PAYETKTVEENIPVHETKTVEEDKPVYETKTVEQSI-PVHETKAIEENIPAYESKT 998
Query: 5241 KENGDPI-----IEEVVPDHSTTTIGKESTNDVHE-----EDKVVAGLDIVGVDKDIGEP 5092
E P+ IEE +P + T T+ E VHE E K + + K E
Sbjct: 999 VEEDKPVYETKTIEEDMPVYETKTV--EEHKPVHESRVIDEHKPLEETKTIEEHKSPYES 1056
Query: 5091 VIKDDVVPDRSTTTIEEEPIQDGQAENEVIEGLEKVELDKDFGDPITEKDVAPDYSITTF 4912
I ++ +P T T+E++P+ + + +E K F + T D P Y
Sbjct: 1057 QIVEENIPVHETKTVEDKPVYESKVIDE----------HKPFEETKTLDDNMPTYESKVI 1106
Query: 4911 DE----ETIKDVHEEDKVIEGAEIGGDNDIGDPVIGEEVVPDNSTTTIRGEPIQDDHEED 4744
DE E K V + E I + + + I EE P + T I EED
Sbjct: 1107 DEHKPFEETKTVDDNMPTYETKAIEENMPVHETKIVEEDKPVHETKAI---------EED 1157
Query: 4743 KMRERLKIDGANKDIVEPTVKDVVLDQSTTTIGETPVKDGHGGHKVTAGLERVGADKDIG 4564
KI V+++ + ++ T + P T + V DK +
Sbjct: 1158 IPVHETKI-----------VENIPVHETKTIEEDIP----------TYETKTVEEDKPVH 1196
Query: 4563 EPITKENVVSDHPIKTIGDIKDDHEEDKVIEGLDIGGNEDIGE--PT-----IEDGISYH 4405
E T E+ + H KT+ + K HE V + + + + + + PT IE+ I H
Sbjct: 1197 ETKTVEDNIPVHETKTVEEDKPVHETKTVEDNIPVHETKTVEDNIPTYETKGIEENIPVH 1256
Query: 4404 STTTTWEEPTKDGHEEKVTEGLEIVDTDENSGNHFIEDDVSEHSTTITGEEAIQNGQEED 4225
T T E+ K HE K E E + +E+ +ED + + T+ E+
Sbjct: 1257 ETKTVEED--KPVHETKAIE--EDIPVNESK---IVEDMPTYETKTV-----------EN 1298
Query: 4224 KMIEGLEKVDADKDIGEPIIEKDGPDHSTTLGAELINDVHDEDKVNEGL-----ERVGSD 4060
+ +K++ K E + +D P + T E I ++ VN+ + + + D
Sbjct: 1299 IPVNETKKIEEHKPAYESKLVEDMPTYETKAIEEDI-PTYETKTVNDNMPIYETKTLEED 1357
Query: 4059 KDTGEPVIVEDVVPDNSTRASGEKPIQDGHG--------EEKITERLEIDRTDKEIGEPT 3904
E IVED+ + KP+ + E KI E + T T
Sbjct: 1358 IPVHETKIVEDMPTYETKTIDEHKPLDETKTIEEHKPAYESKIVEDMPTYET------KT 1411
Query: 3903 MEEGVVLDQSTTIGVEPVVDNYK---EHKVTEGLEIIGENKDIGEPIIEENLVLDHSTTP 3733
+EE L ++ TI +D K EHK T +I+ E+K E E + H T
Sbjct: 1412 VEEDKPLHETKTIDEHKPLDETKTIEEHKSTHESQIVEEDKPAYETKTVEQSIPVHETKA 1471
Query: 3732 IVEIKDGHEEDKVIEGSELAGAEDIGE--PI-----TEEDVSDHTTTTIGKE----PTKD 3586
I E +E V E + + + E P+ E+ + H T I + +K
Sbjct: 1472 IEENIPAYETKTVEENIPVHETKTVEEDKPVYETKTVEQSIPVHETKAIEENIPAYESKT 1531
Query: 3585 VHEEDKAVAFSDLSSADQNFEQVNLSGQTECFEVENLNKHADASTTTHQVIEDPVKEESD 3406
V EEDK S + +E + E + + + + T V ED ES
Sbjct: 1532 V-EEDKPAYESKIVEDMPTYETKTVEEDKPVHETKTVEEDI-PTYETKTVEEDKPVYESK 1589
Query: 3405 VLSQD-RVHEE---DGDNP----KDEEDNVESFEMSKGQEPAISHQEKTIAEATTLIQKS 3250
V+ +D VHE + D P K E+++ ++E +E ++ K I E + +
Sbjct: 1590 VIEEDIPVHETKTVEEDKPVYETKIVEEDIPTYETKTVEEDKPVYESKVIEENIPVHETK 1649
Query: 3249 ETESMK 3232
E K
Sbjct: 1650 TVEEDK 1655
Score = 92.0 bits (227), Expect = 2e-15
Identities = 200/902 (22%), Positives = 352/902 (39%), Gaps = 58/902 (6%)
Frame = -3
Query: 5763 KPFIEDDVIPEHSTTITG-------EKAIRNGQEEDKVIEEL----EKVDAEENIGEPII 5617
KPF+ D+ I E T ++ R+ E K+I++L E+ + ++ I +I
Sbjct: 249 KPFVADNEIVERYVECTDLPPCTEEQRKSRDKYEYKKIIKDLNDEAEQKEYQDTIERKVI 308
Query: 5616 EKDVVPDHATTLGEELINDVHD--DDKVIE--------------GF--EIVGSDKDTGEP 5491
EK + I +H+ D+++ G+ E G+ +D +
Sbjct: 309 EKIREGETEAQANARKIKAIHEFIDNRINAMLNKQYALLNIKPPGYKEETKGNSEDLTDT 368
Query: 5490 VIVEDVVPEHPTTTSGKESIKDGHXXXXXXXXXXXVGADREIREPVIEEDIVPDLSTTTR 5311
I+ +++P T SG ++K ++ +E + E+ P +
Sbjct: 369 NIISEILPPQ-YTVSGNSNLKKYPAKDTDSKKGDNHEPHKDDQEIKVIENYHPKQNGEVE 427
Query: 5310 EEPIEDGHEKN----------KVIEGLEIASSDKENGDPIIEEVVPDHSTTTIGKESTND 5161
+E E ++ + +++E ++ ++K DPI D
Sbjct: 428 KEISEINNDSDGNITKNPTDIRILEKKQLNGNNKHTDDPI-------------DGAQDGD 474
Query: 5160 VHEEDKVVAGLDIVGVDKDIGEPVIKDDVVPDRSTTTIEEEPIQ---DGQAENEVIEGLE 4990
+E + + +I G+DK+ E I +++ D +T+ ++ +PI D + N E
Sbjct: 475 KYEGNVIAENKEIKGIDKNTDETTINNNMRVD-NTSEMKADPIYTSVDHEKNNGNAES-N 532
Query: 4989 KVELDKDFGDPITEKDVAPDYSITTFDEETIKDVHEEDK-VIEGAEIGGDNDIGDPVIGE 4813
K L K+ + + K+ D I F ++T + ++DK ++ E+ G+
Sbjct: 533 KQTLPKEESE--SNKEKYEDKQI--FPDKTKSETEKKDKEIVTDQELNKITQNGNVENKG 588
Query: 4812 EVVPDNSTTTIRGEPIQDDHEEDKMRERLKIDGANKDIVEPTVKDVVLDQSTTTIGETPV 4633
E P+NS T + I + +++ ID N I+E S +T+ E
Sbjct: 589 EENPENSKTIVSDSNI--------LSKQIPID--NTKIIE----------SHSTLDENKT 628
Query: 4632 KDGHGGHKVTAGLERVGADKDIGEPITKENVVSDHPIKTIGDIKDDHEEDKVIEGLDIGG 4453
+G+ T +E G P+ + +V +H K + + K E + V E + G
Sbjct: 629 VEGNISTHETKTVEE-------GIPVHESKIVDEH--KPLEETKKVEEYEPVHESKTVEG 679
Query: 4452 NEDIGEPTIEDGISYHSTTTTWEEPTKDGHEEKVTEGLEIVDTDENSGNHFIEDDVSEHS 4273
N Y S T P + + + E + + +T IE+ H
Sbjct: 680 NIP----------KYESKTVEGNIPAYEN--KTIEEDMPVNETKT------IEEHKPVHE 721
Query: 4272 TTITGEEAIQNGQEEDKMIEGLEKVDADKDIGEPIIEKDGPDHSTTLGAELINDVHD--- 4102
T T E++I E K IE E + A + I+E+D P H T E I VH+
Sbjct: 722 TK-TVEQSIP--VHETKAIE--ENIPAYES---KIVEEDKPVHETKTVEENI-PVHETKT 772
Query: 4101 --EDKVNEGLERVGSDKDTGEPVIVEDVVPDNSTRASGE-KPIQ-----DGHGEEKITER 3946
EDK + V DK E +E+ +P T+ E KP+ D H + T+
Sbjct: 773 VEEDKPVHETKTVEEDKPVYETKTIEEDIPVYETKTVEEHKPVHESKVIDEHKPLEETKT 832
Query: 3945 LEIDRTDKEIGEPTMEEGVVLDQSTTIGVEPVVDN--YKEHKVTEGLEIIGENKDIGEP- 3775
+E ++ E +EE + + ++ T+ +PV ++ EHK E + + +N E
Sbjct: 833 IEEHKSTYE--SQIVEENIPVHETKTVEDKPVYESKVIDEHKPFEETKTVDDNMPTYETK 890
Query: 3774 IIEENLVLDHSTTPIVEIKDGHEEDKVIEGSELAGAEDIGEPITEEDVSDHTTTTIGKEP 3595
IEEN+ + H T + E K HE + EED+ H T + P
Sbjct: 891 AIEENMPV-HETKIVEEDKPVHETKAI-----------------EEDIPVHETKIVENIP 932
Query: 3594 TKDVHEEDKAVAFSDLSSADQNFEQVNLSGQTECFEVENLNKHADASTTTHQVIED-PVK 3418
VHE + E+ + +T+ E EN+ H T V ED PV
Sbjct: 933 ---VHET-------------KTIEENIPAYETKTVE-ENIPVHE-----TKTVEEDKPVY 970
Query: 3417 EESDVLSQDRVHEEDGDNPKDEEDNVESFEMSKGQEPAISHQEKTIAEATTLIQKSETES 3238
E V VHE K E+N+ ++E +E ++ KTI E + + E
Sbjct: 971 ETKTVEQSIPVHET-----KAIEENIPAYESKTVEEDKPVYETKTIEEDMPVYETKTVEE 1025
Query: 3237 MK 3232
K
Sbjct: 1026 HK 1027
Score = 84.7 bits (208), Expect = 3e-13
Identities = 173/772 (22%), Positives = 297/772 (38%), Gaps = 52/772 (6%)
Frame = -3
Query: 5379 ADREIREPVIEEDIVPDLSTTTREEPIEDGHEKNKVIEGLEIASSDKENGDPI----IEE 5212
AD EI E +E +P + R+ D +E K+I+ L + KE D I IE+
Sbjct: 253 ADNEIVERYVECTDLPPCTEEQRKS--RDKYEYKKIIKDLNDEAEQKEYQDTIERKVIEK 310
Query: 5211 VVPDHSTTTIGKESTNDVHE--EDKVVAGLDIVGVDKDIGEPVIKDDVV---PDRSTTTI 5047
+ + +HE ++++ A L+ +I P K++ D + T I
Sbjct: 311 IREGETEAQANARKIKAIHEFIDNRINAMLNKQYALLNIKPPGYKEETKGNSEDLTDTNI 370
Query: 5046 EEE--PIQDGQAENEVIEGLEKVELDKDFGDPITEKDVAPDYSITTFDEETIKDVHEEDK 4873
E P Q + N ++ + D GD + D I + K E +K
Sbjct: 371 ISEILPPQYTVSGNSNLKKYPAKDTDSKKGD--NHEPHKDDQEIKVIENYHPKQNGEVEK 428
Query: 4872 VIEGAEIGGDND---IGDP----VIGEEVVPDNSTTT---IRGEPIQDDHEEDKMRERLK 4723
I +EI D+D +P ++ ++ + N+ T I G D +E + + E +
Sbjct: 429 EI--SEINNDSDGNITKNPTDIRILEKKQLNGNNKHTDDPIDGAQDGDKYEGNVIAENKE 486
Query: 4722 IDGANKDIVEPTVKDVVLDQSTTTIGETPVKDGHGGHKVTAGLERVGADKDIGEPITKEN 4543
I G +K+ E T+ + + +T+ + P+ K E E + +
Sbjct: 487 IKGIDKNTDETTINNNMRVDNTSEMKADPIYTSVDHEKNNGNAESNKQTLPKEESESNKE 546
Query: 4542 VVSDHPI----------KTIGDIKDDHEEDKVIEGLDIGGNEDIGEPTIEDGISYHSTTT 4393
D I K +I D E +K+ + G E+ GE E+ + S +
Sbjct: 547 KYEDKQIFPDKTKSETEKKDKEIVTDQELNKITQN---GNVENKGEENPENSKTIVSDSN 603
Query: 4392 TWEEPTKDGHEEKVTEGLEIVDTDENSGNHFIEDDVSEHSTTITGEEAIQNGQ------- 4234
+ + K+ E +D N +E ++S H T T EE I +
Sbjct: 604 ILSKQIPIDNT-KIIESHSTLDE-----NKTVEGNISTHETK-TVEEGIPVHESKIVDEH 656
Query: 4233 ---EEDKMIEGLEKVDADKDIGEPIIEKDGPDHSTTLGAELINDVHDEDKVNEGLERVGS 4063
EE K +E E V K + I + + + A + ++ VNE + +
Sbjct: 657 KPLEETKKVEEYEPVHESKTVEGNIPKYESKTVEGNIPAYENKTIEEDMPVNE-TKTIEE 715
Query: 4062 DKDTGEPVIVEDVVPDNSTRASGEK-PIQDGHGEEKITERLEIDRTDKEIGEP-TMEEGV 3889
K E VE +P + T+A E P E KI E DK + E T+EE +
Sbjct: 716 HKPVHETKTVEQSIPVHETKAIEENIPAY----ESKIVEE------DKPVHETKTVEENI 765
Query: 3888 VLDQSTTIGVEPVVDNYKEHKVTEGLEIIGENKDIGE--PIIEENLVLDHSTTPIVEIKD 3715
+ ++ T+ + V E K E + + E K I E P+ E V +H ++ D
Sbjct: 766 PVHETKTVEEDKPVH---ETKTVEEDKPVYETKTIEEDIPVYETKTVEEHKPVHESKVID 822
Query: 3714 GH---EEDKVIEGSELAGAEDIGEPITEEDVSDHTTTTIGKEPTKDVHEEDKAVAFSDLS 3544
H EE K IE + I EE++ H T T+ +P + D+ F +
Sbjct: 823 EHKPLEETKTIEEHK----STYESQIVEENIPVHETKTVEDKPVYESKVIDEHKPFEETK 878
Query: 3543 SADQNFEQVNLSGQTECFEVENLNKHADASTTTHQ---VIEDPVKEESDVLSQDRVHEED 3373
+ D N E V K + H+ + ED E+ ++ VHE
Sbjct: 879 TVDDNMPTYETKAIEENMPVHE-TKIVEEDKPVHETKAIEEDIPVHETKIVENIPVHET- 936
Query: 3372 GDNPKDEEDNVESFEMSKGQEPAISHQEKTIAEATTLIQ-KSETESMKLNRT 3220
K E+N+ ++E +E H+ KT+ E + + K+ +S+ ++ T
Sbjct: 937 ----KTIEENIPAYETKTVEENIPVHETKTVEEDKPVYETKTVEQSIPVHET 984
Score = 73.2 bits (178), Expect = 9e-10
Identities = 109/492 (22%), Positives = 213/492 (43%), Gaps = 58/492 (11%)
Frame = -1
Query: 2921 EEQVIKEIPEKTESANHETIFVTQPTEKLSLHEAEPQGGELVDASD--DASVEMFSTPI- 2751
E ++EI ES +TI +P E+ E E + + +DASD D + + I
Sbjct: 2030 ENNTVEEIIPVHES---KTIKEHKPLEETKTIE-EHKPVDTIDASDIIDKGISIDDNKII 2085
Query: 2750 EEHGASSLDPD--MEDVKQGEIATLDDNATDNTFTAENAETEHEKPEVPVENSAVATQSV 2577
+E+G D D +E++ G +T N +DN+ + E E+ VP +N +T ++
Sbjct: 2086 QENGGRISDKDEAIENL-DGYESTKSTNYSDNS-----DDNEEEEIIVPNQNIDSSTSNI 2139
Query: 2576 DKDTQTTLVSEITASKASSDDLSEE---KPQKSSMLISAKNEFNAV----------GMKE 2436
D + + + +K + D E + +K + ++N + V G+
Sbjct: 2140 INDQSKIIYTGKSVNKTLNSDSDENMHMESRKEDIQKESENNKDVVSHIPDDKIIHGVVN 2199
Query: 2435 KIKEECQIDDEIKDKKMEAPL-VAQTKGEVNMQTEEHLNLEKDSEMGIENTEQKISVXXX 2259
+++ ID++ + +E L V ++G N H+ + D+ + N +KI
Sbjct: 2200 NDEKKLLIDEKNIEDILEKDLNVDNSEGRSNEYNTIHMQNKADTILDEHNNREKIDNNGK 2259
Query: 2258 XXXXXXXEQK-DADVSLEREKI----IELNEYKENNRSETSDSGLKETKFE--------S 2118
++ + D+ +ER+ + I + + K+ + ++ +K+ + +
Sbjct: 2260 ISEQISEDKSYNLDIKVERDALPHDSINIQKAKDEADIKKEEADIKKEEADIKKDEADIK 2319
Query: 2117 EEEFDACSKELETTGTCANI---ETDILEQEEDALKKLDQNLESEKGTMKVEEIQVEV-- 1953
++E D +E + A+I ETDI ++EE +KK + +++ E K +I+ E
Sbjct: 2320 KDEADIKKEETDIQKEEADIKKEETDIQKEEEAVIKKDEADIKKETDIKKETDIKKETDI 2379
Query: 1952 ---KATDHSHKINESHNTAESALLAQDN-------LEAIDPCDEIKRDT----EST---- 1827
+A I+ + E L+ +DN + + CDE R++ EST
Sbjct: 2380 KKDEAVIKKEDISMNKEIDEKKLIIEDNTNCPPNVITIKEKCDETARESDVNPESTIIKD 2439
Query: 1826 --DHDQSKEALSEIEKTEVVEDKEIMKYQNVV-SVEDHTVGESIQDEENENDSLDEAGPK 1656
D +IEKTE E E + +V+ +D + E I D N+N + +E G K
Sbjct: 2440 KDDVSTENSNTEKIEKTEKTEKTEKTEKNDVIDDSDDFNINEIISDVVNDNVNSNENGNK 2499
Query: 1655 LNANDQNDDMND 1620
+ N++ ++D
Sbjct: 2500 YDQNEKLGMLDD 2511
Score = 66.2 bits (160), Expect = 1e-07
Identities = 184/931 (19%), Positives = 348/931 (37%), Gaps = 74/931 (7%)
Frame = -1
Query: 3059 EIVTLEEETPKNSLNDFRATEAPLEEITKMKKSDKLNY-TPTESAMSEEQVIKEIPEKTE 2883
E T+EE+ P + + P+ E TK + DK Y T T K I E
Sbjct: 1647 ETKTVEEDKPVHETKAIEE-DIPVHE-TKTVEEDKPVYETKTVDDNMPTYETKGIEENMP 1704
Query: 2882 SANHETIFVTQP-----TEKLSLHEAEPQGGELVDASDDASVEMFSTPIEEHGASSLDPD 2718
HET V + T+ + H+ + + D + I H +++
Sbjct: 1705 V--HETKIVEEDKPLEETKTIEEHKPTYETKTVDDNMPTYETKGIEENIPVHETKTIE-- 1760
Query: 2717 MEDVKQGEIATLDDNATDNTFTAENAETEHEKP---------EVPVENSAVATQSVDKDT 2565
ED+ E T++DN E+ E +KP +PV + + DK
Sbjct: 1761 -EDIPTYETKTVNDNMP----IYESKTVEEDKPTYETKGIEENIPVHETKTVEE--DKPV 1813
Query: 2564 QTTLVSEITASKASSDDLSEEKPQKSSMLISAKNEFNAVGMKEKIKEECQIDDEIKDKKM 2385
T E S + E+KP + I + KI EE + +E K +
Sbjct: 1814 HETKAIEEDIPAYESKIVEEDKPVYETKTIDEDKPV----YETKIVEEYKPLEETKTIEE 1869
Query: 2384 EAPLVAQTKGEVNMQTEEHLNLEKDSEMGIENTEQKISVXXXXXXXXXXEQKDADVSLER 2205
P +TK +M T E L++ + E KI + D+ +
Sbjct: 1870 HKPTY-ETKIVEDMPTYETKTLDEHKHVH----ESKIV--------------EDDIPVHE 1910
Query: 2204 EKIIELNEYKENNRSETSDSGLKETKFESEEEFDACSKELETTGTC---ANIETDILEQE 2034
K+IE ++ + N+ D + ETK E+ +K +E +E DI E
Sbjct: 1911 TKVIEEHKPLDENKVIEEDIPVYETKTVEEDNPTYETKTVEENIPVYENKTVEEDIPVHE 1970
Query: 2033 EDAL---------KKLDQNLESEKGTMKVEEIQV-EVKATDHSHKINESHNTAESALLAQ 1884
+ K +D++ E+ E+I + E K D ++E+ E + +
Sbjct: 1971 TKTIEEVIPTYENKVIDEHKPFEETKTIEEDISLDENKVIDEVIPLHETKTVEEGIPVHE 2030
Query: 1883 DN-LEAIDPCDEIKRDTESTDHDQSKEALSEIEKTEVVEDKEIMKYQNVVSVEDHTV--- 1716
+N +E I P E K E +++K + E + + ++ +I+ +S++D+ +
Sbjct: 2031 NNTVEEIIPVHESKTIKEHKPLEETK-TIEEHKPVDTIDASDII--DKGISIDDNKIIQE 2087
Query: 1715 -GESIQDEENENDSLD--EAGPKLNANDQNDDMNDVNPPIKDAIVNEEMPHGVERADNGR 1545
G I D++ ++LD E+ N +D +DD + EE+ + D+
Sbjct: 2088 NGGRISDKDEAIENLDGYESTKSTNYSDNSDDNEE-----------EEIIVPNQNIDSST 2136
Query: 1544 EETLVGEVGEQCKVDPNFESDLQNEGADKGNDEEDKCRKLDAXXXXXXXXXXXXXXVGKQ 1365
+ +Q K+ +S + +D + + RK D K+
Sbjct: 2137 SNI----INDQSKIIYTGKSVNKTLNSDSDENMHMESRKEDIQ---------------KE 2177
Query: 1364 LEEESDLV---PGELINEIVTNRTEN----EGGAPKDTTDTDGVIDVNKPAESTFST--- 1215
E D+V P + I V N E + +D + D +D ++ + ++T
Sbjct: 2178 SENNKDVVSHIPDDKIIHGVVNNDEKKLLIDEKNIEDILEKDLNVDNSEGRSNEYNTIHM 2237
Query: 1214 -NTTSTIEKLHIDEKLLTDNPDASSLTEASQESMQEKEGKNTEDGEKQEVVFVKKATKDM 1038
N TI H + + + +N S + S++ + K D + + ++KA +
Sbjct: 2238 QNKADTILDEHNNREKIDNNGKISE--QISEDKSYNLDIKVERDALPHDSINIQKAKDEA 2295
Query: 1037 GLPTEES---RENIEHEAPVAEMSKEGG---KKINEVSIEEKSFRNEEGETQVLKQPDTP 876
+ EE+ +E + + A++ K+ K+ ++ EE + EE + Q ++
Sbjct: 2296 DIKKEEADIKKEEADIKKDEADIKKDEADIKKEETDIQKEEADIKKEETDIQKEEEAVIK 2355
Query: 875 RDLQMLDQSSDVTAE----QEASIETDSIEKTKENISIG------------SIEIPSAPV 744
+D + + +D+ E +E I+ D KE+IS+ + P +
Sbjct: 2356 KDEADIKKETDIKKETDIKKETDIKKDEAVIKKEDISMNKEIDEKKLIIEDNTNCPPNVI 2415
Query: 743 DVIEKSLQTA-EVEEGKHGEVQGNDSELNTVECEASFDEETNTNSKSSEAKGASLFD--- 576
+ EK +TA E + + + +++T E+T K+ + + + D
Sbjct: 2416 TIKEKCDETARESDVNPESTIIKDKDDVSTENSNTEKIEKTEKTEKTEKTEKNDVIDDSD 2475
Query: 575 --LLNKPRKDTGQAVEQFEEEGNSTSNKEQL 489
+N+ D E GN E+L
Sbjct: 2476 DFNINEIISDVVNDNVNSNENGNKYDQNEKL 2506
>gb|ACJ64146.1| sporozoite-specific transmembrane protein S6 precursor [Plasmodium
berghei]
Length = 2301
Score = 142 bits (358), Expect = 1e-30
Identities = 263/1141 (23%), Positives = 467/1141 (40%), Gaps = 104/1141 (9%)
Frame = -3
Query: 6390 DVAPDHSITAFEE-EPI--KYVHEEDKVIEGTEIIGADKDIGDPIIGEEIVPDHSTTTIR 6220
+V P H EE +P+ V EE + T+ + K + + + EE++P H T T+
Sbjct: 650 EVIPAHETKTVEEYKPLDESRVVEEVIPVHETKTVEEYKPLDESRVVEEVIPVHETKTVE 709
Query: 6219 G-EPIQDDH--EEDKVTEELKIDGANKDIGEPS-IKDVVLDQSTSSIGE-TPAKDGH--- 6064
+P+ + EE K +E K K + E +++V+ T ++ E P +
Sbjct: 710 EYKPLYESRVIEEHKPLDETKTVEEYKPLDESRVVEEVIPVNETKTVEEYKPLYESRVIE 769
Query: 6063 -----EEHKLVGADKDIGKTIIKENVIPDHPIKTIGEIKHDHEEDKVIEGLD--IDCGNE 5905
+E K V K + ++ + E P KT+ E K + E +VIEG +
Sbjct: 770 EYKPLDETKTVEEYKPLYESRVIEEYKPLDETKTVEEYKPLY-ESRVIEGYKPLYETKTV 828
Query: 5904 DNGEPITEEDGVRGHS--TKTTWEEPAKDGHEEKVTKGLEIVDTNKNCG--KPFIE---- 5749
+ +P+ E + H +T E K +E +V + + +D K KP E
Sbjct: 829 EEYKPLYESRVIEEHKPLDETKTVEEYKPLYESRVIEEHKPLDETKTVEEYKPLDESRVV 888
Query: 5748 DDVIPEHST-TITGEKAIRNGQ--EEDKVIEELEKVDAEENIGEPIIEKDVVPDHATTLG 5578
++VIP + T T+ K + + EE K ++E + V+ + + E + +DV+P H T
Sbjct: 889 EEVIPVNETKTVEEYKPLNESRVIEEYKPLDETKTVEEYKPLDESRVVEDVIPVHETKTV 948
Query: 5577 EELINDVHDDDKVIEGF------EIVGSDKDTGEPVIVEDVVPEHPTTTSGKESIKDGHX 5416
EE D+ +VIE + V K E +VEDV+P H T T +
Sbjct: 949 EEY--KPLDESRVIEEVIPVHETKTVEEYKPLYESRVVEDVIPVHETKTVEEY------- 999
Query: 5415 XXXXXXXXXXVGADREIREPVIEEDIVPDLSTTTREE--PIEDGH--EKNKVIEGLEIAS 5248
+ + E + E+++P T T EE P+ + E++K ++ +
Sbjct: 1000 --------------KPLDESRVVEEVIPVHETKTVEEYKPLYESRVIEEHKPLDETKTVE 1045
Query: 5247 SDKE-NGDPIIEEVVPDHSTTTIGKES---TNDVHEEDKVVAGLDIVGVDKDIGEPVIKD 5080
K + ++EEV+P H T T+ + + V EE K + V K + E + +
Sbjct: 1046 EYKPLDESRVVEEVIPVHETKTVEEYKPLYESRVIEEHKPLDETKTVEEYKPLDESRVVE 1105
Query: 5079 DVVPDRSTTTIEE-EPIQDGQAENEVI--EGLEKVELDKDFGDPITEKDVAPDYSITTFD 4909
DV+P T T+EE +P+ + + EVI + VE K + ++V P T +
Sbjct: 1106 DVIPVHETKTVEEYKPLDESRVVEEVIPVHETKTVEEYKPLDESRVVEEVIPVNETKTVE 1165
Query: 4908 E----------------------ETIKDVHEEDKVIEGAEIGGDNDIGD--PVIGEEVVP 4801
E E K ++E + E + + + P+ G V+
Sbjct: 1166 EYKPLYESRVIEEYKPLDETKTVEEYKPLYESRVIEEYKPLDETKTVEEYKPLYGSRVIE 1225
Query: 4800 -----DNSTTTIRGEPIQDDH--EEDKMRERLKIDGANKDIVEP-TVKDVVLDQSTTTIG 4645
D + T +P+ + E K K K + E V++V+ T T+
Sbjct: 1226 EYKPLDETKTVEEYKPLYESRVIEGYKPLYETKTVEEYKPLYESRVVEEVIPVNETKTVE 1285
Query: 4644 E-TPVKDGHGGHKVTAGLE--RVGADKDIGEPITKENVVSDHPIKTIGDIKDDHEEDKVI 4474
E P+ + V E V K + E E V+ H KT+ + K +E V
Sbjct: 1286 EYKPLDESRVVEDVIPVHETKTVEEYKPLDESRVVEEVIPVHETKTVEEYKPLYESRVVE 1345
Query: 4473 EGLDIGGNEDIGE-------PTIEDGISYHSTTTTWEEPTKDGHEEKVTEGLEIVDTDEN 4315
E + + + + E +ED I H T T E D E +V E + +D
Sbjct: 1346 EVIPVNETKTVEEYKPLDESKVVEDVIPVHETKTVEEYKPLD--ESRVVEEYKPLDE--- 1400
Query: 4314 SGNHFIEDDVSEHSTTITGEEAIQNGQEEDKMIEGLEKVDADKDIGE-------PIIEKD 4156
+ +E+ + H T I E E ++IE + +D K + E +IE+
Sbjct: 1401 --SRVVEEVIPVHETKIVEE---YKPLYESRVIEEYKPLDETKTVEEYKPLYESRVIEEH 1455
Query: 4155 GP-DHSTTLGAELINDVHDEDKVNEGLERVGSDKDTGEPVIVEDVVPDNSTRASGE-KPI 3982
P D + T+ +E K + V K E +VE+V+P + T+ E KP+
Sbjct: 1456 KPLDETKTV---------EEYKPLDESRVVEEYKPLNESRVVEEVIPVHETKTVEEYKPL 1506
Query: 3981 QDGHGEEKITERLEIDRTDKEIGEPTMEEGVVLDQSTTIGVEPVVDNYKEHKVTEGLEII 3802
+ I E +D T T+EE L++S VE V+ + E K E + +
Sbjct: 1507 YE---SRVIEEHKPLDET------KTVEEYKPLNESRV--VEEVIHAH-ETKTVEEYKPL 1554
Query: 3801 GENKDIGE-PIIEENLVLDHSTTPIVEIKDGHEEDKVIEGSELAGAEDIGEPITEEDVSD 3625
E++ I E + +EN V++ E+ HE KV E L G+ + +ED+
Sbjct: 1555 DESRVIDEHKLFDENRVVE-------EVIPAHETKKVEEYKPLYGSR-----VIDEDIPA 1602
Query: 3624 HTTTTIGK-EPTKDVHEEDKAVAFSDLSSADQN---FEQVNLSGQTECFEVENLNKHA-- 3463
+ T T+ + +P + ++ + + + D++ E + +E + ++KH
Sbjct: 1603 YETKTVDEHKPLDESIVVEEVIPVHETKTIDEHKPLDESRVIEEDIPAYETKTVDKHKLF 1662
Query: 3462 DASTTTHQVIEDPVKEESDVLSQDRVHEEDGDNPKDEEDNVESFEMSKGQEPAISHQEKT 3283
D S +VI P E V + V D ++ + +++ ++ +G + IS +++
Sbjct: 1663 DESRVVEEVI--PAYESKTVDERKLVDSIDANDIIGKGESIYDNKIIQGNDEWISDKDEA 1720
Query: 3282 I 3280
I
Sbjct: 1721 I 1721
Score = 128 bits (321), Expect = 2e-26
Identities = 258/1137 (22%), Positives = 449/1137 (39%), Gaps = 142/1137 (12%)
Frame = -3
Query: 6258 EEIVPDH--STTTIRGEPIQDDHEEDKVTEELKIDGANKDIGEPSIKDVV----LDQSTS 6097
++I PD S T + + I D E +K+T+ ++ + I K V LD+S
Sbjct: 612 KQIFPDKTKSETEKKDKEIIRDQELNKITQNGNVENIVEVIPAHETKTVEEYKPLDESRV 671
Query: 6096 SIGETPAKDGHEEHKLVGADKDIGKTIIKENVIPDHPIKTIGEIKHDHEEDKVIEGLDID 5917
P E K V K + ++ + E VIP H KT+ E K +E + E +D
Sbjct: 672 VEEVIPV----HETKTVEEYKPLDESRVVEEVIPVHETKTVEEYKPLYESRVIEEHKPLD 727
Query: 5916 -CGNEDNGEPITE----EDGVRGHSTKTTWE----------------------EPAKDGH 5818
+ +P+ E E+ + + TKT E E K +
Sbjct: 728 ETKTVEEYKPLDESRVVEEVIPVNETKTVEEYKPLYESRVIEEYKPLDETKTVEEYKPLY 787
Query: 5817 EEKVTKGLEIVDTNKNCG--------------------------KPFIEDDVIPEH---- 5728
E +V + + +D K KP E VI EH
Sbjct: 788 ESRVIEEYKPLDETKTVEEYKPLYESRVIEGYKPLYETKTVEEYKPLYESRVIEEHKPLD 847
Query: 5727 -STTITGEKAIRNGQ--EEDKVIEELEKVDAEENIGEPIIEKDVVPDHATTLGEEL--IN 5563
+ T+ K + + EE K ++E + V+ + + E + ++V+P + T EE +N
Sbjct: 848 ETKTVEEYKPLYESRVIEEHKPLDETKTVEEYKPLDESRVVEEVIPVNETKTVEEYKPLN 907
Query: 5562 D--VHDDDKVIEGFEIVGSDKDTGEPVIVEDVVPEHPTTTSGKESIKDGHXXXXXXXXXX 5389
+ V ++ K ++ + V K E +VEDV+P H T T +
Sbjct: 908 ESRVIEEYKPLDETKTVEEYKPLDESRVVEDVIPVHETKTVEEY---------------- 951
Query: 5388 XVGADREIREPVIEEDIVPDLSTTTREE--PIEDGHEKNKVIEGLEIASSDKE---NGDP 5224
+ + E + E+++P T T EE P+ + VI E + ++ +
Sbjct: 952 -----KPLDESRVIEEVIPVHETKTVEEYKPLYESRVVEDVIPVHETKTVEEYKPLDESR 1006
Query: 5223 IIEEVVPDHSTTTIGKES---TNDVHEEDKVVAGLDIVGVDKDIGEPVIKDDVVPDRSTT 5053
++EEV+P H T T+ + + V EE K + V K + E + ++V+P T
Sbjct: 1007 VVEEVIPVHETKTVEEYKPLYESRVIEEHKPLDETKTVEEYKPLDESRVVEEVIPVHETK 1066
Query: 5052 TIEE-EPIQDGQA--ENEVIEGLEKVELDKDFGDPITEKDVAPDYSITTFDE----ETIK 4894
T+EE +P+ + + E++ ++ + VE K + +DV P + T +E + +
Sbjct: 1067 TVEEYKPLYESRVIEEHKPLDETKTVEEYKPLDESRVVEDVIPVHETKTVEEYKPLDESR 1126
Query: 4893 DVHEEDKVIEGAEIGGDNDIGDPVIGEEVVPDNSTTTIRG-EPIQDDH--EEDKMRERLK 4723
V E V E + + + + EEV+P N T T+ +P+ + EE K + K
Sbjct: 1127 VVEEVIPVHETKTVEEYKPLDESRVVEEVIPVNETKTVEEYKPLYESRVIEEYKPLDETK 1186
Query: 4722 IDGANKDIVEPTVKDVV--LDQSTTTIGETPVKDGHGGHKVTAGLERVGADKDIGE--PI 4555
K + E V + LD++ T P+ G +V + + K + E P+
Sbjct: 1187 TVEEYKPLYESRVIEEYKPLDETKTVEEYKPLY----GSRVIEEYKPLDETKTVEEYKPL 1242
Query: 4554 TKENVVSD----HPIKTIGDIKDDHEEDKVIEGLDIGGNEDIGE-------PTIEDGISY 4408
+ V+ + KT+ + K +E V E + + + + E +ED I
Sbjct: 1243 YESRVIEGYKPLYETKTVEEYKPLYESRVVEEVIPVNETKTVEEYKPLDESRVVEDVIPV 1302
Query: 4407 HSTTTTWEEPTKDGHEEKVTEGLEIVDTDENSGNHFIEDDVSEHSTTITGEEAIQNGQEE 4228
H T T E D E +V E E++ E +E+ + + + E N E
Sbjct: 1303 HETKTVEEYKPLD--ESRVVE--EVIPVHETK---TVEEYKPLYESRVVEEVIPVN---E 1352
Query: 4227 DKMIEGLEKVDADKDIGEPIIEKDGPDHSTTLGAELINDVHDEDKVNEGLERVGSDKDTG 4048
K +E + +D K ++E P H T E DE +V V K
Sbjct: 1353 TKTVEEYKPLDESK-----VVEDVIPVHETKTVEEY--KPLDESRV------VEEYKPLD 1399
Query: 4047 EPVIVEDVVPDNSTRASGE-KPIQDGHGEEKITERLEIDRTDKEIGEPTMEEGVVLDQST 3871
E +VE+V+P + T+ E KP+ + I E +D T T+EE L +S
Sbjct: 1400 ESRVVEEVIPVHETKIVEEYKPLYE---SRVIEEYKPLDET------KTVEEYKPLYESR 1450
Query: 3870 TIGVEPVVDNYK---EHKVTEGLEIIGENKDIGEPIIEENLVLDHSTTPIVEIKDGHEED 3700
I +D K E+K + ++ E K + E + E ++ H T + E K +E
Sbjct: 1451 VIEEHKPLDETKTVEEYKPLDESRVVEEYKPLNESRVVEEVIPVHETKTVEEYKPLYESR 1510
Query: 3699 KVIEGSELAGAEDIGE-------PITEEDVSDHTTTTIGKEPTKDVHEEDKAVAFSDLSS 3541
+ E L + + E + EE + H T T+ + D E + + L
Sbjct: 1511 VIEEHKPLDETKTVEEYKPLNESRVVEEVIHAHETKTVEEYKPLD---ESRVIDEHKLFD 1567
Query: 3540 ADQNFEQVNLSGQTE-------------------CFEVENLNKH--ADASTTTHQVI--- 3433
++ E+V + +T+ +E + +++H D S +VI
Sbjct: 1568 ENRVVEEVIPAHETKKVEEYKPLYGSRVIDEDIPAYETKTVDEHKPLDESIVVEEVIPVH 1627
Query: 3432 EDPVKEESDVLSQDRVHEEDGDNPKDEEDNVES---FEMSKGQEPAI-SHQEKTIAE 3274
E +E L + RV EE D P E V+ F+ S+ E I +++ KT+ E
Sbjct: 1628 ETKTIDEHKPLDESRVIEE--DIPAYETKTVDKHKLFDESRVVEEVIPAYESKTVDE 1682
Score = 123 bits (308), Expect = 8e-25
Identities = 252/1149 (21%), Positives = 460/1149 (40%), Gaps = 67/1149 (5%)
Frame = -3
Query: 6450 IEGLENVDLDKDIGEPITEKDVAPDHSITAFEE-EPIKY--VHEEDKVIEGTEIIGADKD 6280
++ + V+ K + E ++V P + EE +P+ V EE K ++ T+ + K
Sbjct: 870 LDETKTVEEYKPLDESRVVEEVIPVNETKTVEEYKPLNESRVIEEYKPLDETKTVEEYKP 929
Query: 6279 IGDPIIGEEIVPDHSTTTIRG-EPIQDDH--EEDKVTEELKIDGANKDIGEPSIKDVVLD 6109
+ + + E+++P H T T+ +P+ + EE E K K + E + + V+
Sbjct: 930 LDESRVVEDVIPVHETKTVEEYKPLDESRVIEEVIPVHETKTVEEYKPLYESRVVEDVIP 989
Query: 6108 QSTSSIGETPAKDGHEEHKLVGADKDIGKTIIKENVIPDHPIKTIGEIKHDHEEDKVIEG 5929
E K V K + ++ + E VIP H KT+ E K +E + E
Sbjct: 990 V--------------HETKTVEEYKPLDESRVVEEVIPVHETKTVEEYKPLYESRVIEEH 1035
Query: 5928 LDID-CGNEDNGEPITE----EDGVRGHSTKTTWEEPAKDGHEEKVTKGLEIVDTNKNCG 5764
+D + +P+ E E+ + H TKT E K +E +V + + +D K
Sbjct: 1036 KPLDETKTVEEYKPLDESRVVEEVIPVHETKTV--EEYKPLYESRVIEEHKPLDETKTVE 1093
Query: 5763 --KPFIE----DDVIPEHST-TITGEKAIRNGQEEDKVI--EELEKVDAEENIGEPIIEK 5611
KP E +DVIP H T T+ K + + ++VI E + V+ + + E + +
Sbjct: 1094 EYKPLDESRVVEDVIPVHETKTVEEYKPLDESRVVEEVIPVHETKTVEEYKPLDESRVVE 1153
Query: 5610 DVVPDHATTLGEE----LINDVHDDDKVIEGFEIVGSDKDTGEPVIVEDVVPEHPTTTSG 5443
+V+P + T EE + V ++ K ++ + V K E ++E+ P T T
Sbjct: 1154 EVIPVNETKTVEEYKPLYESRVIEEYKPLDETKTVEEYKPLYESRVIEEYKPLDETKTVE 1213
Query: 5442 KESIKDGHXXXXXXXXXXXVGADREIREPVIEEDIVPDLSTTTRE-EPIEDGHEKNKVIE 5266
+ G VIEE D + T E +P+ + ++VIE
Sbjct: 1214 EYKPLYG--------------------SRVIEEYKPLDETKTVEEYKPLYE----SRVIE 1249
Query: 5265 GLEIASSDK--ENGDP-----IIEEVVPDHSTTTIGKESTNDVHEEDKVVAGLDIVGVD- 5110
G + K E P ++EEV+P + T T+ + D E +VV D++ V
Sbjct: 1250 GYKPLYETKTVEEYKPLYESRVVEEVIPVNETKTVEEYKPLD---ESRVVE--DVIPVHE 1304
Query: 5109 -------KDIGEPVIKDDVVPDRSTTTIEE-EPIQDGQAENEVI--EGLEKVELDKDFGD 4960
K + E + ++V+P T T+EE +P+ + + EVI + VE K +
Sbjct: 1305 TKTVEEYKPLDESRVVEEVIPVHETKTVEEYKPLYESRVVEEVIPVNETKTVEEYKPLDE 1364
Query: 4959 PITEKDVAPDYSITTFDEETIKDVHEEDKVIEGAEIGGDNDIGDPVIGEEVVPDNSTTTI 4780
+DV P + T +E D E +V+E + + + + EEV+P + T +
Sbjct: 1365 SKVVEDVIPVHETKTVEEYKPLD---ESRVVEEYK-----PLDESRVVEEVIPVHETKIV 1416
Query: 4779 RG-EPIQDDH--EEDKMRERLKIDGANKDIVEPTV--KDVVLDQSTTTIGETPVKDGHGG 4615
+P+ + EE K + K K + E V + LD++ T P+ +
Sbjct: 1417 EEYKPLYESRVIEEYKPLDETKTVEEYKPLYESRVIEEHKPLDETKTVEEYKPLDES--- 1473
Query: 4614 HKVTAGLERVGADKDIGEPITKENVVSDHPIKTIGDIKDDHEEDKVIEGLDIGGNEDIGE 4435
V K + E E V+ H KT+ + K +E + E + + + E
Sbjct: 1474 -------RVVEEYKPLNESRVVEEVIPVHETKTVEEYKPLYESRVIEEHKPLDETKTVEE 1526
Query: 4434 -------PTIEDGISYHSTTTTWEEPTKDGHEEKVTEGLEIVDTDENSGNHFIEDDVSEH 4276
+E+ I H T T E D E +V + ++ D N +E+ + H
Sbjct: 1527 YKPLNESRVVEEVIHAHETKTVEEYKPLD--ESRVIDEHKLFDE-----NRVVEEVIPAH 1579
Query: 4275 STTITGEEAIQNGQEEDKMIEGLEKVDADKDI-GEPIIEKDGPDHSTTLGAELINDVHDE 4099
T +KV+ K + G +I++D P + T
Sbjct: 1580 ET---------------------KKVEEYKPLYGSRVIDEDIPAYET------------- 1605
Query: 4098 DKVNEGLERVGSDKDTGEPVIVEDVVPDNSTRASGE-KPIQDGHGEEKITERLEIDRTDK 3922
+ V K E ++VE+V+P + T+ E KP+ + E+ E DK
Sbjct: 1606 -------KTVDEHKPLDESIVVEEVIPVHETKTIDEHKPLDESRVIEEDIPAYETKTVDK 1658
Query: 3921 E---IGEPTMEEGVVLDQSTTIGVEPVVDNYKEHKVTEGLEIIGENKDIGEPIIEENLVL 3751
+EE + +S T+ +VD+ + + E I +NK II+ N
Sbjct: 1659 HKLFDESRVVEEVIPAYESKTVDERKLVDSIDANDIIGKGESIYDNK-----IIQGNDEW 1713
Query: 3750 DHSTTPIVEIKDGHEEDKVIEGSELAGAEDIGEPITEEDVSDHTTTTIGKEPTKDVHEED 3571
+E DG+E K S+ + + G+ I D +T+ + + +K ++ D
Sbjct: 1714 ISDKDEAIENLDGYESTKSTNYSDNSDDNEEGKSIFPNKNIDLSTSNVINDQSKIIY-TD 1772
Query: 3570 KAVAFSDLSSADQNFEQVNLSGQTECFEVENLN-----KHADASTTTHQVIEDPVKEESD 3406
K+V + ++D N E ++ + E + E+ N H H+V + K+
Sbjct: 1773 KSV--NKTINSDPN-ENIHTESRKEDIQKESENNKDMISHIPDDRIIHRVANNGEKKL-- 1827
Query: 3405 VLSQDRVHEEDGDNPKDEEDNVESFEMSKGQEPAI--SHQEKTIAEATTLIQKSETESMK 3232
+ E++ ++ ++ NV++ E + I H+E + + I+K++
Sbjct: 1828 -----LIDEKNIEDILGKDLNVDNSEGGSNEYNTIDMEHKEDSTLDEHNNIEKNDNNGKI 1882
Query: 3231 LNRTGEPDS 3205
+ E S
Sbjct: 1883 SEHSSEDKS 1891
Score = 120 bits (302), Expect = 4e-24
Identities = 239/1119 (21%), Positives = 440/1119 (39%), Gaps = 50/1119 (4%)
Frame = -3
Query: 6438 ENVDLDKDIGEPITEKDVAPDHSITAFEEEPIKY---VHEEDKVIEGTEIIGADKDIGDP 6268
+ V+ K + E ++V P H EE Y V EE K ++ T+ + K + +
Sbjct: 994 KTVEEYKPLDESRVVEEVIPVHETKTVEEYKPLYESRVIEEHKPLDETKTVEEYKPLDES 1053
Query: 6267 IIGEEIVPDHSTTTIRG-EPIQDDH--EEDKVTEELKIDGANKDIGEPSIKDVVLDQSTS 6097
+ EE++P H T T+ +P+ + EE K +E K K + E + + V+
Sbjct: 1054 RVVEEVIPVHETKTVEEYKPLYESRVIEEHKPLDETKTVEEYKPLDESRVVEDVIPV--- 1110
Query: 6096 SIGETPAKDGHEEHKLVGADKDIGKTIIKENVIPDHPIKTIGEIKHDHEEDKVIEGLDID 5917
E K V K + ++ + E VIP H KT+ E K +E +V+E +
Sbjct: 1111 -----------HETKTVEEYKPLDESRVVEEVIPVHETKTVEEYK-PLDESRVVEEV--- 1155
Query: 5916 CGNEDNGEPITEEDGVRGHSTKTTWEEPAKDGHEEKVTKGLEIVDTNKNCG--KPFIEDD 5743
P+ E TKT E K +E +V + + +D K KP E
Sbjct: 1156 -------IPVNE--------TKTV--EEYKPLYESRVIEEYKPLDETKTVEEYKPLYESR 1198
Query: 5742 VIPEH-----STTITGEKAIRNGQEEDKVIEELEKVDAEENIGE--PIIEKDVVPDHATT 5584
VI E+ + T+ K + +VIEE + +D + + E P+ E V+ +
Sbjct: 1199 VIEEYKPLDETKTVEEYKPLYG----SRVIEEYKPLDETKTVEEYKPLYESRVIEGYKPL 1254
Query: 5583 LGEELINDVHD--DDKVIEGF------EIVGSDKDTGEPVIVEDVVPEHPTTTSGKESIK 5428
+ + + + +V+E + V K E +VEDV+P H T T +
Sbjct: 1255 YETKTVEEYKPLYESRVVEEVIPVNETKTVEEYKPLDESRVVEDVIPVHETKTVEEY--- 1311
Query: 5427 DGHXXXXXXXXXXXVGADREIREPVIEEDIVPDLSTTTREE--PIEDGHEKNKVIEGLEI 5254
+ + E + E+++P T T EE P+ + +VI E
Sbjct: 1312 ------------------KPLDESRVVEEVIPVHETKTVEEYKPLYESRVVEEVIPVNET 1353
Query: 5253 ASSDKE---NGDPIIEEVVPDHSTTTIGKESTNDVHEEDKVVAGLDIVGVDKDIGEPVIK 5083
+ ++ + ++E+V+P H T T+ EE K + +V K + E +
Sbjct: 1354 KTVEEYKPLDESKVVEDVIPVHETKTV---------EEYKPLDESRVVEEYKPLDESRVV 1404
Query: 5082 DDVVPDRSTTTIEE-EPIQDGQAENEVIEGLEKVELDKDFGDPITEKDVAPDYSITTFDE 4906
++V+P T +EE +P+ E+ VIE + ++ K T ++ P Y +E
Sbjct: 1405 EEVIPVHETKIVEEYKPLY----ESRVIEEYKPLDETK------TVEEYKPLYESRVIEE 1454
Query: 4905 ----ETIKDVHEEDKVIEGAEIGGDNDIGDPVIGEEVVPDNSTTTIRG-EPIQDDH--EE 4747
+ K V E + E + + + + EEV+P + T T+ +P+ + EE
Sbjct: 1455 HKPLDETKTVEEYKPLDESRVVEEYKPLNESRVVEEVIPVHETKTVEEYKPLYESRVIEE 1514
Query: 4746 DKMRERLKIDGANKDIVEP-TVKDVVLDQSTTTIGETPVKDGHGGHKVTAGLERVGADKD 4570
K + K K + E V++V+ T T+ E
Sbjct: 1515 HKPLDETKTVEEYKPLNESRVVEEVIHAHETKTVEEY----------------------- 1551
Query: 4569 IGEPITKENVVSDHPI----KTIGDIKDDHEEDKVIEGLDIGGNEDIGEPTIEDGISYHS 4402
+P+ + V+ +H + + + ++ HE KV E + G+ I ED +Y +
Sbjct: 1552 --KPLDESRVIDEHKLFDENRVVEEVIPAHETKKVEEYKPLYGSRVID----EDIPAYET 1605
Query: 4401 TTTTWEEPTKDG-HEEKVTEGLEIVDTDEN---SGNHFIEDDVSEHSTTITGEEAIQNGQ 4234
T +P + E+V E DE+ + IE+D+ + T + +
Sbjct: 1606 KTVDEHKPLDESIVVEEVIPVHETKTIDEHKPLDESRVIEEDIPAYETKTVDKHKL---F 1662
Query: 4233 EEDKMIEGLEKVDADKDIGEPIIEKDGPDHSTTLG-AELINDVHDEDKVNEGLERVGSDK 4057
+E +++E + K + E + D D + +G E I D +K+ +G + SDK
Sbjct: 1663 DESRVVEEVIPAYESKTVDERKL-VDSIDANDIIGKGESIYD----NKIIQGNDEWISDK 1717
Query: 4056 DTGEPVIVEDVVPDNSTRASGEKPIQDGHGEEK-ITERLEIDRTDKEIGEPTMEEGVVLD 3880
D +E++ ST+++ D + E K I ID + V+ D
Sbjct: 1718 DEA----IENLDGYESTKSTNYSDNSDDNEEGKSIFPNKNIDLS---------TSNVIND 1764
Query: 3879 QSTTIGVEPVVDNYKEHKVTEGLEIIGENKDIGEPIIEENLVLDH--STTPIVEIKDGHE 3706
QS I + V+ E + +DI + ++ H I + + E
Sbjct: 1765 QSKIIYTDKSVNKTINSDPNENIHTESRKEDIQKESENNKDMISHIPDDRIIHRVANNGE 1824
Query: 3705 EDKVIEGSELAGAEDIGEPITEEDVSDHTTTTIGKEPTKDVHEEDKAVAFSDLSSADQNF 3526
+ +I+ + + + + TI E H+ED + + ++ ++N
Sbjct: 1825 KKLLIDEKNIEDILGKDLNVDNSEGGSNEYNTIDME-----HKEDSTL--DEHNNIEKND 1877
Query: 3525 EQVNLSGQTECFEVENLNKHADASTTTHQVIEDPVKEESDVLSQDRVHEEDGDNPKDEED 3346
+S + + ++ D T H I +++ D + + +E+ D KDE
Sbjct: 1878 NNGKISEHSSEDKSYTIDIKVDRDTLPHDSIN--IQKTKD---EAAIKKEEADTKKDEAA 1932
Query: 3345 -NVESFEMSKGQEPAISHQEKTIAEATTLIQKSETESMK 3232
E ++ KG E AI E I + +I+K E ++ K
Sbjct: 1933 IKKEEVDIKKG-EAAIKKYEVDIKKGEAVIKKEEADTKK 1970
Score = 96.7 bits (239), Expect = 8e-17
Identities = 208/884 (23%), Positives = 345/884 (39%), Gaps = 67/884 (7%)
Frame = -3
Query: 6438 ENVDLDKDIGEPITEKDVAPDHSITAFEEEPIKYVHEEDKVIEGTEIIGADKDIGDPIIG 6259
+ V+ K + E +DV P H EE K ++ + ++ K + + +
Sbjct: 1354 KTVEEYKPLDESKVVEDVIPVHETKTVEEY---------KPLDESRVVEEYKPLDESRVV 1404
Query: 6258 EEIVPDHSTTTIRG-EPIQDDHEEDKVTEELKIDGANKDIGE--PSIKDVVLDQSTSSIG 6088
EE++P H T + +P+ E +V EE K K + E P + V+++ +
Sbjct: 1405 EEVIPVHETKIVEEYKPLY----ESRVIEEYKPLDETKTVEEYKPLYESRVIEEH-KPLD 1459
Query: 6087 ETPAKDGH---EEHKLVGADKDIGKTIIKENVIPDHPIKTIGEIKHDHEEDKVIEGLDID 5917
ET + + +E ++V K + ++ + E VIP H KT+ E K +E + E +D
Sbjct: 1460 ETKTVEEYKPLDESRVVEEYKPLNESRVVEEVIPVHETKTVEEYKPLYESRVIEEHKPLD 1519
Query: 5916 -CGNEDNGEPITE----EDGVRGHSTKTTWEEPAKDGHEEKVTKGLEIVDTNKNCGKPFI 5752
+ +P+ E E+ + H TKT E D E +V ++ D N+ +
Sbjct: 1520 ETKTVEEYKPLNESRVVEEVIHAHETKTVEEYKPLD--ESRVIDEHKLFDENR------V 1571
Query: 5751 EDDVIPEHSTTITGEKAIRNGQ---EEDKVIEELEKVDAEENIGEPIIEKDVVPDHATTL 5581
++VIP H T E G +ED E + VD + + E I+ ++V+P H T
Sbjct: 1572 VEEVIPAHETKKVEEYKPLYGSRVIDEDIPAYETKTVDEHKPLDESIVVEEVIPVHETKT 1631
Query: 5580 GEELINDVHDDDKVIE----GFEIVGSDKDT--GEPVIVEDVVPEHPTTTSGKESIKDGH 5419
+E + D+ +VIE +E DK E +VE+V+P + + T
Sbjct: 1632 IDE--HKPLDESRVIEEDIPAYETKTVDKHKLFDESRVVEEVIPAYESKTVD-------- 1681
Query: 5418 XXXXXXXXXXXVGADREIREPVIEEDIVPDLSTTTREEPIEDGHEKNKVIEGLEIASSDK 5239
+R++ + + DI+ + E I D NK+I+G + SDK
Sbjct: 1682 --------------ERKLVDSIDANDII------GKGESIYD----NKIIQGNDEWISDK 1717
Query: 5238 ENGDPIIEEVVPDHSTTTIGKESTNDVHEEDKVV-----AGLDIVGVDKDIGEPVIKDDV 5074
D IE + ST + +D +EE K + L V D + + D
Sbjct: 1718 ---DEAIENLDGYESTKSTNYSDNSDDNEEGKSIFPNKNIDLSTSNVINDQSKIIYTDKS 1774
Query: 5073 VPDRSTTTIEEEPIQDGQAENEVIEGLEKVELDKDF-----GDPITEKDVAPDYSITTFD 4909
V TI +P ++ E+ + ++ E +KD D I + D
Sbjct: 1775 V----NKTINSDPNENIHTESRKEDIQKESENNKDMISHIPDDRIIHRVANNGEKKLLID 1830
Query: 4908 EETIKDVHEEDKVIEGAEIGGDNDIG--DPVIGEEVVPDNSTTTIRGE---PIQDDHEED 4744
E+ I+D+ +D ++ +E GG N+ D E+ D + + I + ED
Sbjct: 1831 EKNIEDILGKDLNVDNSE-GGSNEYNTIDMEHKEDSTLDEHNNIEKNDNNGKISEHSSED 1889
Query: 4743 KM--------RERLKIDGAN--KDIVEPTVK----DVVLDQSTTTIGETPVKDGHGGHKV 4606
K R+ L D N K E +K D D++ E +K G
Sbjct: 1890 KSYTIDIKVDRDTLPHDSINIQKTKDEAAIKKEEADTKKDEAAIKKEEVDIKKGE----- 1944
Query: 4605 TAGLERVGADKDIGEPITKENVVSDHP-----IKTIGDIKDDHEEDKVIEGLDIGGNE-- 4447
A +++ D GE + K+ K DIK D K E +DI +E
Sbjct: 1945 -AAIKKYEVDIKKGEAVIKKEEADTKKDEAAIKKEEVDIKKDEAAIKK-EEVDIKKDEAA 2002
Query: 4446 ------DI--GEPTI--EDGISYHSTTTTWEEPTKDGHEEKVTEGLEIVDTDENSGNHFI 4297
DI GE I E+ +S H+ +P K E+ I E
Sbjct: 2003 IKKYEVDIKKGEAAIKKEEAVSMHNEI----DPKKLIIEDNTNCPPNITTIKEKCDEVPK 2058
Query: 4296 EDDVSEHSTTITGEEAIQNGQEEDKMIEGLEKVDADKDIGEPIIEKDGPDHSTTLGA-EL 4120
+ DV+ T I +DK EK + +K+ D D+S E+
Sbjct: 2059 KSDVNPERTII-----------KDKDYVSTEKSNIEKN--------DVIDNSDDFSINEI 2099
Query: 4119 INDVHDEDKVNEGLERVGSDKDTGEPVIVEDVVPDNSTRASGEK 3988
I+ V +E + E S DT E + + D + S +ASGEK
Sbjct: 2100 ISAVVNEHVNSNDAE---SKYDTNEKLGILDDFVEKSKKASGEK 2140
>gb|AAF15293.3| erythrocyte membrane-associated giant protein antigen 332 [Plasmodium
falciparum]
Length = 5458
Score = 140 bits (354), Expect = 4e-30
Identities = 247/1105 (22%), Positives = 456/1105 (41%), Gaps = 47/1105 (4%)
Frame = -3
Query: 6408 EPITEKDVAPDHSITAF-----EEEPIKYVHEEDKVIEGTEIIGADKDIGDPIIGE---- 6256
+ +TEK + + S T E+E HE++ V ++ K + I+ E
Sbjct: 1989 DSVTEKVIEQEGSNTEVAEDVEEKESASDEHEQEDVSVNAQVTCEKKSVTKEIVDEVSRT 2048
Query: 6255 -EIVPDHSTTTIRGEPIQDDHEEDKVTEELKIDGANKDIGEPSIKDVVLDQSTSSIGETP 6079
EIV ++ + T + E VTEE+ I E ++ + V++ S+ E
Sbjct: 2049 EEIVEENGSVT------EGVDETGSVTEEI--------IEEATVTEEVVEDG--SVTEEV 2092
Query: 6078 AKDGHEEHKLVGADKDIGKTIIKEN-VIPDHPIKTIGEIKHDHEEDKVIEGLDIDCGNED 5902
+DG ++V D + + I++EN + + ++ G + + EE+ + G D
Sbjct: 2093 VEDGSVIQEVV-EDGSVTEEIVQENGSVTEEIVEEEGSVNEEVEEEVSVSG------EVD 2145
Query: 5901 NGEPITEEDGVRGHSTKTTWEEPAKDGHEEKVTKGLEIVDTNKNCGKPFIEDDVIPEHST 5722
E +TEE G + EE E +G + + + G + ++++ E +
Sbjct: 2146 ETEYVTEEVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGS--VVEEIVEEEGS 2203
Query: 5721 TITGEKAIRNGQEEDKVIEELEKVDAEENIGEPIIEKD--VVPDHATTLGEELINDVHDD 5548
+ E+ + +EE V+EE+ V+ E ++ E I+E++ VV + G + V ++
Sbjct: 2204 VV--EEIV---EEEGSVVEEI--VEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEE 2256
Query: 5547 DKVIEGFEIVGSDKDTGEPVIVEDVVPEHPTTTSGKESIKDGHXXXXXXXXXXXVGADRE 5368
V+E EIV E +VE++V E + E I + E
Sbjct: 2257 GSVVE--EIVEE-----EGSVVEEIVEEEGSVV---EEIVEEEGSVVEEIVEEEGSVVEE 2306
Query: 5367 I--REPVIEEDIVPDLSTTTREEPIEDGHEKNKVIEGLEIASSDKENGDPIIEEVVPDHS 5194
I E + E+IV + + EE +E+ ++V++ E+ + + P EEV
Sbjct: 2307 IVEEEGSVVEEIVEEEGSVV-EEIVEEEGSVSEVVDETELVNDEIVEQAPFTEEVEE--- 2362
Query: 5193 TTTIGKESTNDVHEEDKVVAGLDIVGVDKDIGEPVIKDD-------VVPDRSTTTIEEEP 5035
+ S ND ED VA + V + I E V +++ + T + EE
Sbjct: 2363 -----QVSVNDEIIEDASVA--EAVEESESITESVSQEEETEKGFVIEKVEETGAVTEEI 2415
Query: 5034 IQDGQAENEVIEGLEKVELDKDFGDPITEKDVAPDYSITTF------------DEETIKD 4891
+QDG E++E E V G+ I ++ A + T F EE +++
Sbjct: 2416 VQDGLITEEILEESESVN-----GEIINKESDAEEILETEFLTEEVVGQAGSTSEEIVEE 2470
Query: 4890 VHEEDKVIEGAEIGGDNDIGDPVIGEEVVPDNSTTTI----RGEPIQDDHEEDKMRERLK 4723
K +E E + + + + EE+V + S T G Q+ EE+ E +
Sbjct: 2471 EGSVTKEVEEKESVTEELVDEGSVTEELVDEGSVTEEVVEQGGSIAQEIVEEESATEEII 2530
Query: 4722 IDGANKDIVEPTVKDVVLDQSTTTIGETPVKDGHGGHKVTAGLERVGADKDIGEPITKEN 4543
D N V++V+ + + T E V+DG G + + VG + E + +E
Sbjct: 2531 RDETN-------VEEVLEKEGSAT--EEIVQDGSGTN------DFVGKQGSVIEEVVEEE 2575
Query: 4542 V-VSDHPIKTIGDIKDDHEEDKVIEGLDIGGNEDIGEPTIEDGISYHSTTTTWEEPTKDG 4366
+ ++ +K EE IE + E I E +E+ + + G
Sbjct: 2576 ISTTEEKLK---------EEASAIE--EFVEEESIREDVLEESLVTENVV---------G 2615
Query: 4365 HEEKVTEGLEIVDTDENSGNHFIEDDVSEHSTTITGEEAIQNGQEEDKMIEGLEKVDADK 4186
+E VTE EIVD + + +E++ S + EE++ ED+ + E V+ +
Sbjct: 2616 QQESVTE--EIVDGEGSFTEDIVEEEESVTEEIVVDEESVTKEIVEDEELVTEEIVEDEG 2673
Query: 4185 DIGEPIIEKDGPDHSTTLGAE-LINDVHDEDKVNEGLERVGSDKDTGEPVIVEDVVPDNS 4009
E I+E +G + LI +V D + V E E + E + E +V +
Sbjct: 2674 SFTEEIVEDEGSFTEEVIEERSLIEEVEDTETVAEKEEGSVIKEIIDEKSLTEKIVEE-- 2731
Query: 4008 TRASGEKPI-QDGHGEEKITERLEIDRTDKEIGEPTMEEGVVLDQSTTIGVEPVVDNYKE 3832
EK + ++ +E + E +E R E E + EG+V D+ T G+ V D
Sbjct: 2732 -----EKSVTEEVEEKESVKEEVEEQRLVVE-EEGSATEGIVEDRLATEGI--VDDILVT 2783
Query: 3831 HKVTEGLEIIGENKDIGEPIIEENLVLDHSTTPIVEIKDGHEEDKVIEGSELAGAEDIGE 3652
++ E E + IIEE L + S T + ++G ++++EG + +D E
Sbjct: 2784 EEIVEDGLATDEFVEQQGSIIEEVLDDEGSVTEEIVEEEGSPNEEIVEGVSVIEEDDNIE 2843
Query: 3651 PITEEDVSDHTTTTIGKEPTKD--VHEEDKAVAFSDLSSADQNFEQVNLSGQTECFEVEN 3478
P++EE V T + KE ++ + +ED + + E V G V+
Sbjct: 2844 PVSEEIVEGSVTEEMIKEGLENEVILDEDSITEEALEKEGSVSEEIVEEMGSLTEEIVDE 2903
Query: 3477 LNKHADASTTTHQVIEDPVKEESDVLSQDRVHEEDGDNPKDEEDNVESFEMSK----GQE 3310
++ E+ ++EES V ++ V E + EED +++ E+ + E
Sbjct: 2904 ERSTSEDMIEEGSASEEIIQEESQV--EEVVEEVSVIDEIVEEDELDTKEVVEEIEFNTE 2961
Query: 3309 PAISHQEKTIAEATTLIQKSETESM 3235
+ H+E+ + A ++Q+ + S+
Sbjct: 2962 EVVEHKEEEGSVAEEIVQEEKEGSV 2986
Score = 127 bits (320), Expect = 3e-26
Identities = 234/1118 (20%), Positives = 458/1118 (40%), Gaps = 114/1118 (10%)
Frame = -3
Query: 6264 IGEEIVPDHSTTTIRGEPIQDDHEEDKVTEELKIDGANKDIGEPSIKDVVLDQSTSSIGE 6085
+ EE+V + + T + ++ E+ + E + + ++I E I + + S E
Sbjct: 3745 VNEEVVEEEGSVTEEIKEQEESVNEEVLEEVEETESIKEEIVEGGIATQEIIEEESDTKE 3804
Query: 6084 TPAKDGHEEHKLVGADKDIGKTIIKENVIPDHPIKTIGEIKHDHEEDKVIEGLDIDCGNE 5905
++ + KLV A G+ + +E + D ++ + EE K + ++
Sbjct: 3805 VVEEEVIDSEKLVDAGSVTGEVMPEEVSVTDEVVEEGSTTEEVLEEQKSVNEEVVE---- 3860
Query: 5904 DNGEPITEEDGVRGHSTKTTWEEPAKDGHE--EKVTKGLEIVDTNKNCGKPFIE------ 5749
+G I + G++G +T+ EE + E+ T EIV+ + + +E
Sbjct: 3861 -DGLTIDDFVGLQGSTTEEVVEEDGSAIEKILEEETATEEIVEKQVSVTEDIVEKEGSVN 3919
Query: 5748 DDVIPEHSTTITGEKAIRNGQEEDKVIEELEKVDAEENIGEPIIEKDVVPDHATTLGEEL 5569
+++I E S E+ I+ G ++++ + E E E +I ++ + ++ EE+
Sbjct: 3920 EEIIEEASVA---EEIIQGGSFTEEIVGQEESATEEVIDEEGLISNEIEEEEEKSVTEEM 3976
Query: 5568 INDVHDDDKVIEGFEIVGSDKDTGEPVIVEDVVPEHPTTT-------------------- 5449
I +V + E E+ +++ E ++ ++++PE + T
Sbjct: 3977 IEEVEEVSVDDEVEEVSVAEEIVEEELVDDEILPEELSATEDVIEEVRSVTDEIVQEESV 4036
Query: 5448 ----------SGKESIKD--------GHXXXXXXXXXXXVGADREIRE---PVIEEDIVP 5332
+ +E + D GH EI E VIEE +
Sbjct: 4037 CEEILEQEVSASEEYVDDKSVTDDFVGHERSVIQDVENTESVTEEIAEVDKSVIEEAVEK 4096
Query: 5331 DLSTTTR---------EEPIEDGHEKNKVIEGLEIASSDKENGDPIIEEV---------- 5209
S T EE +ED V+E + E + EEV
Sbjct: 4097 QGSVTEEIVEEEELDTEEVLEDKSVTGDVVEQEGSGKDESEAKESFTEEVDELKSVKEED 4156
Query: 5208 -VPDHSTTTIGKESTNDVHEEDKVVAGLDIVGVDKDIGEPVIKDDVVPDRSTTTIEEEPI 5032
++ + I +ES + H E ++ ++V + + D+ ++STT +E +
Sbjct: 4157 QETEYISREIEEESATEQHSEQELSINKEVVETES------LTKDIEEEKSTT---QEIL 4207
Query: 5031 QDGQAENEVIEGLEKVELDKDFGDPITEK-----DVAPDYSITTFDEETIKDVHEEDKVI 4867
++ Q+ NE E VE ++D + + EK +V + + TT EE +++ D+++
Sbjct: 4208 EETQSVNE-----EIVEEERDTDEVLKEKVSPSEEVIEEQASTT--EEFLEERSSTDEIV 4260
Query: 4866 EGAEIGGDN-DIGDPVIGEEVVPDNSTT----TIRGEPIQDDHEEDKMRERL--KIDGAN 4708
E ++ + + + EE+V + S T G ++ EE E + +
Sbjct: 4261 EVEDLFTEEVKEREGSVTEEIVEEGSDTGEIVEEEGSDAEEILEEGSFNEEIVEEEGSIT 4320
Query: 4707 KDIVEPTVKDVVLDQSTTTIGETPVKDGHGGHKV--TAGLERVGADKDIGEPITKENVVS 4534
++I++ +V + + Q + I E + +V + E V + + E + +E S
Sbjct: 4321 EEILQGSVTEEFVGQQGSVIEEIVETESAIEERVEDESATEEVDERESVTEVVEEEVSSS 4380
Query: 4533 DHPIKTIGDIKDDHE-EDKVIEGL---DIGGNEDIGEPTIEDGISYHSTTTTWEEPTKDG 4366
D ++ G I++ E E V E + ++ +E+ + T + EE ++
Sbjct: 4381 DEVVE--GSIEEVIENEGSVTEEILEHEVSADENFVGQAVSVIEEVEGTESVTEEVVEE- 4437
Query: 4365 HEEKVTEGLEIVDTDEN---SGNHFIEDDVSEHSTTITGEEAIQNGQEEDKMIEGLEKVD 4195
E V+E + V EN + IE+DV + + E I + D +E EK+
Sbjct: 4438 -TESVSEEIVEVSPTENVVQQTDSVIEEDVEQKEGSF--NEEIDIRELGDDGVEEREKIS 4494
Query: 4194 ADKDIG-EPIIEKDGPDHSTTLGAELINDVHDEDKVN--EGLERVGSDKDTGEPVIVEDV 4024
++ +G + D + S+T E ++ DE++V+ EGLE V S + E EDV
Sbjct: 4495 TEEVVGQDKSATGDVEESSSTGDVEEVSSTEDEEEVSSTEGLEEVSSTEGLEEVSNTEDV 4554
Query: 4023 VPDNSTRASGEKPIQDGHGEEK-ITERLEIDRTDKEIGEPTMEEGVVLDQSTTIGVEPVV 3847
+ST E + + E K ITE + ++ D + ++E+ V+ + S + V
Sbjct: 4555 EEVSSTEDVEEGSVAENVKETKSITEEVSVEE-DIITDKVSVEQEVMAEASVEENILTEV 4613
Query: 3846 DNYKEHKVTEGLEIIGENKDIGEPII-EENLVLD----HSTTP----IVEIKDGHEEDKV 3694
+E +TE L + E+K + E I+ EE +V++ H P + E G EE
Sbjct: 4614 P-VEEEIMTEKLSV--EDKALNEKIMSEEEIVIEDGNVHEVVPAEVSVTEEIPGVEETTN 4670
Query: 3693 IEGSELAGAEDIGEPITEED-------VSDHTTTTIGKEPTKDV-HEEDKAVAFSDLSSA 3538
E S + G + E + +++ D ++ I +KDV H+E+ +F + +
Sbjct: 4671 NE-SHVKGENVVNEVVVDDNSVNDEIQFDDDSSIEIYTVDSKDVFHKEENYDSFREEVRS 4729
Query: 3537 DQNFEQVNLSGQTECFEVENLNKHADASTTTHQVIEDPVKEE--SDVLSQDRVHEEDGDN 3364
D+N + ++EN K + T ++ + EE S ++ ++ V EE
Sbjct: 4730 DENIHISRKKNENFVKKIEN-EKSSVGHVPTEYTSKENIAEEVPSHIMFKENVTEEVPKE 4788
Query: 3363 PKDEEDNVES-FEMSKGQEPAISHQEKTIAEATTLIQK 3253
K EE+ VE FE +E I I +I++
Sbjct: 4789 VKYEENTVEEVFEEVTSKENIIEEAPGDINSEENIIEE 4826
Score = 124 bits (311), Expect = 3e-25
Identities = 245/1151 (21%), Positives = 477/1151 (41%), Gaps = 99/1151 (8%)
Frame = -3
Query: 6354 EEPIKYVHEEDKVIEGTEIIGADKDIGDPIIGEEIVPDHSTTTIRGEPIQDDHEEDKVTE 6175
EE + V D+VIE +K + + I+GEE ++ +P++ E TE
Sbjct: 1713 EEIVNEVSVTDEVIE------EEKLVNEQIVGEE-------RSVTEKPVE---VERSATE 1756
Query: 6174 ELKIDGANK----DIGEPSIKDVVLDQSTSSIGETPAKDGHEEHKLVGADKDIGKTIIKE 6007
+L +GA+ + E S + +LD+S + E ++ + K++ + + + + +E
Sbjct: 1757 DLVEEGASVTEKVSVHEGSTTEQILDESVAE--EIVEEEVSVDDKIIEEEVSVDEVVEEE 1814
Query: 6006 NVIPDHPIKTIGEIKHDHEEDKVIEGLDI-------DCGNEDNGEPITE-EDGVRGHSTK 5851
+ + ++ + + E+++ ++ D G I E E+ V G +
Sbjct: 1815 GSVIEEIVEEEESVPEEILEEELSGSEEVLEDEWVTDAFMGQEGSVIEEIEEIVDGEGSI 1874
Query: 5850 TTWEEPAKDGHEEKVTKGLEIVDTNKNCGKP-FIEDDVIPEHSTT--ITGEKAIRNGQEE 5680
T EE +DG + E + GK F+ +++I E S + K + EE
Sbjct: 1875 T--EEIVEDGSANEKIVEEEPSRVEEVLGKEGFVIEEIIEEGSVIEQVEDTKTVSEKSEE 1932
Query: 5679 DKVIEELEKVDAEENIGEPIIEKD-------VVPDHATTLGEELINDVHDDDKVIEGFEI 5521
IEE+++V EE+I E I+EK+ V + +TT E+++ DV + +E
Sbjct: 1933 SSAIEEVKEVKEEESISEKIVEKEESVTEEIVRQEESTT--EKIVKDVSPTEDFVE---- 1986
Query: 5520 VGSDKDTGEPVIVEDVVPEHPTTTSGKESIKDGHXXXXXXXXXXXVGADREIREPVIE-- 5347
+D T + + E E KES D H + + + +++
Sbjct: 1987 -QTDSVTEKVIEQEGSNTEVAEDVEEKESASDEHEQEDVSVNAQVTCEKKSVTKEIVDEV 2045
Query: 5346 ---EDIVPDLSTTTR-------------------EEPIEDGHEKNKVIEGLEIASSDKEN 5233
E+IV + + T EE +EDG +V+E + E+
Sbjct: 2046 SRTEEIVEENGSVTEGVDETGSVTEEIIEEATVTEEVVEDGSVTEEVVEDGSVIQEVVED 2105
Query: 5232 GDPIIEEVVPDHSTTT--IGKE--STNDVHEEDKVVAGL--DIVGVDKDIGEPVIKDDVV 5071
G + EE+V ++ + T I +E S N+ EE+ V+G + V +++ E + +
Sbjct: 2106 GS-VTEEIVQENGSVTEEIVEEEGSVNEEVEEEVSVSGEVDETEYVTEEVEEEGSVVEEI 2164
Query: 5070 PDRSTTTIEEEPIQDGQAENEVIEG-----LEKVELDKDFGDPITEKDVAPDYSITTFDE 4906
+ + +EE ++G E++E E VE + + I E++ + I +
Sbjct: 2165 VEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEG 2224
Query: 4905 ETIKDVHEEDKVIEGAEIGGDNDIGDPVIGEEVVPDNSTTTIRGEPIQDDHEED--KMRE 4732
++++ EE+ + + + + + ++ EE G +++ EE+ + E
Sbjct: 2225 SVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEE 2284
Query: 4731 RLKIDGA-NKDIVEP--TVKDVVLDQSTTTIGETPVKDGHGGHKVTAGLERVGADKDIGE 4561
++ +G+ ++IVE +V + ++++ + + E ++G + E V + + E
Sbjct: 2285 IVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEG------SVVEEIVEEEGSVSE 2338
Query: 4560 PITKENVVSDHPIKTIGDIKDDHEE----DKVIEGLDIGGNEDIGEPTIEDGISYHSTTT 4393
+ + +V+D ++ ++ E+ D++IE + +E+ S + +
Sbjct: 2339 VVDETELVNDEIVEQAPFTEEVEEQVSVNDEIIEDASVA-------EAVEESESITESVS 2391
Query: 4392 TWEEPTKDGHEEKVTEGLEIVDTDENSGNHFIEDDVSEHSTTITGEEAIQNGQEEDKMIE 4213
EE K EKV E + T+E + I +++ E S ++ G E I + ++++E
Sbjct: 2392 QEEETEKGFVIEKVEETGAV--TEEIVQDGLITEEILEESESVNG-EIINKESDAEEILE 2448
Query: 4212 ----GLEKVDADKDIGEPIIEKDGPDHSTTLGAELINDVHDEDKVNEGLERVGS--DKDT 4051
E V E I+E++G + +V +++ V E L GS ++
Sbjct: 2449 TEFLTEEVVGQAGSTSEEIVEEEG---------SVTKEVEEKESVTEELVDEGSVTEELV 2499
Query: 4050 GEPVIVEDVVPDNSTRASGEKPIQDGHGEEKITERLEIDRTDKE---IGEPTMEEGVVLD 3880
E + E+VV + A Q+ EE TE + D T+ E E + E +V D
Sbjct: 2500 DEGSVTEEVVEQGGSIA------QEIVEEESATEEIIRDETNVEEVLEKEGSATEEIVQD 2553
Query: 3879 QSTT---IG-----VEPVVD---NYKEHKVTE---GLEIIGENKDIGEPIIEENLVLDH- 3745
S T +G +E VV+ + E K+ E +E E + I E ++EE+LV ++
Sbjct: 2554 GSGTNDFVGKQGSVIEEVVEEEISTTEEKLKEEASAIEEFVEEESIREDVLEESLVTENV 2613
Query: 3744 ---STTPIVEIKDGHEEDKVIEGSELAGAEDIGEPITEEDVSDHTTTTIGKEPTKDVHEE 3574
+ EI DG EGS + E +TEE V D + TK++ E+
Sbjct: 2614 VGQQESVTEEIVDG-------EGSFTEDIVEEEESVTEEIVVDEESV------TKEIVED 2660
Query: 3573 DKAVAFSDLSSADQNFEQVNLSGQTECFEVENLNKHADASTTTHQVIEDPVKEESDVLSQ 3394
++ V E++ VE D + T +++ED +V+ +
Sbjct: 2661 EELVT-----------EEI----------VE------DEGSFTEEIVEDEGSFTEEVIEE 2693
Query: 3393 DRVHEEDGDN----PKDEEDNVESFEMSKGQEPAISHQEKTIAEATTLIQ--KSETESMK 3232
+ EE D K+E ++ K I +EK++ E + K E E +
Sbjct: 2694 RSLIEEVEDTETVAEKEEGSVIKEIIDEKSLTEKIVEEEKSVTEEVEEKESVKEEVEEQR 2753
Query: 3231 LNRTGEPDSTE 3199
L E +TE
Sbjct: 2754 LVVEEEGSATE 2764
Score = 121 bits (303), Expect = 3e-24
Identities = 231/1043 (22%), Positives = 424/1043 (40%), Gaps = 49/1043 (4%)
Frame = -3
Query: 6357 EEEPIKYVHEEDKVIEGTEIIGADKDIGDPIIGEEIVPDHSTTTIRGEPIQDDHEEDKVT 6178
+E I+ + +E+K E TE ++ + + + +E T+ E I D +E++ T
Sbjct: 24 KENEIEKIMDENKETEQTEEGNTEEFVQEKELNQE--------TLENEIIVDHIKEEEDT 75
Query: 6177 EELKIDGANKDIGEPSIKDVVLDQSTSSIGETPAKDGHEEHKLVGADKDIGKTIIKENVI 5998
+K + S + E+P ++ E+ + ++++ + I+ E +
Sbjct: 76 RNVK-------------------EQESVLEESPIEELPVENNIGKINEEVEEFILNEIPL 116
Query: 5997 PDHPIKTIGEIKHDHEEDKVIEGLDIDCGNEDNGEPITEEDGVRGH--------STKTTW 5842
+ K E+ + E+ V+E L ID +TEED +G K+
Sbjct: 117 EEQVPK---ELPQEEIEEIVVEELPIDEHLSSEETTVTEEDTFKGQLINEEKPVEEKSVS 173
Query: 5841 EE-PAKDG--------HEEKVTKGLEIVDTNKNCGKPFIEDDV---IPEHSTTITGEKAI 5698
EE P ++ E+ V++ + + + N + P E +V IP ++ E +
Sbjct: 174 EEIPVEEKSVSEEIPVEEKSVSEEIPVEEKNVSEEIPVEEKNVSEEIPVEEKNVSEEIPV 233
Query: 5697 RNGQEEDKVIEELEKVDAE-----ENIGEPIIEKDV----VPDHATTLGEELINDVHDDD 5545
+++ E E V E EN+ E I E + VP T+ EE+ D D
Sbjct: 234 EEENVSEEIPVEEENVSEEIPVEEENVSEEIPEGGIAIEDVPVDEETVTEEITVDEKIYD 293
Query: 5544 KVIEGFEIVGSDKDTGEPVIVEDVVPEHPTTTSGKESIKDGHXXXXXXXXXXXVGADRE- 5368
K+ E V + + + E + EH +E I++ G + E
Sbjct: 294 KLPNEIETVNEEMPVEDETLTEQISSEHERVP--EEIIEE---------KPFTEGEETES 342
Query: 5367 IREPVIEEDIVPDLSTTTREEPIEDGHEKNKVIEGLEIASSDKENGDPIIEEVVPDHSTT 5188
+ + ++EE +V D E+ I + KV E E + + D I E+V + +
Sbjct: 343 LTDEIVEEGVVTD--DIPEEQIITE-----KVQEEEEFVTGELSEEDIINEKVQEEDESV 395
Query: 5187 T---IGKESTNDVHEEDKVVAGLDIV---GVDKDIGEPVIKDDVVPDRSTTTIEEEPIQD 5026
T ++ N+ +E++ A +IV V KD+ + +D V D+ IEE+P +
Sbjct: 396 TEELPEEDIINEKVQEEEESAYQEIVQDGSVTKDVEYKELVNDDVRDKENFVIEEDPFK- 454
Query: 5025 GQAENEVIEGLEKVELDKDFGDPITEKDVAPDYSITTFDEETIKDVHEEDKVI--EGAEI 4852
GQ NE + +E+ + K+ P+ E+ V + +T D+ K++ E+ + E EI
Sbjct: 455 GQLINEGLP-VEEEFVTKEL--PVKEESVFEE--LTEEDQSVTKEIPVEEHSVFKEVDEI 509
Query: 4851 GGDNDIGDPVIGEEVVPDNSTTTIRGEPIQDDHEEDKMRERLKIDGANKDIVEPTVKDVV 4672
+ EE+V + + +++ E + + G D E ++V
Sbjct: 510 ES--------VTEEIVEEEGSV------------NEEVEEEVSVSG-EVDETEYVTEEV- 547
Query: 4671 LDQSTTTIGETPVK-DGHGGHKVTAGLERVGADKDIGEPITKENVVSDHPIKTIGDIKDD 4495
+ T + E +K +G KV + +E S+ ++ G + ++
Sbjct: 548 --EETELVNEEVLKEEGSASEKV----------------VKEEGSASEKIVEEEGSVTEE 589
Query: 4494 HEEDKVIEGLDIGGNEDIGEPTIEDGISYHSTTTTWEEPTKDGHEEKVTEGLEIVDTDEN 4315
++++E E E +ED S +++ E ++G + + IV+ + +
Sbjct: 590 TASEEIVEEEGSVTEESSSEEIVEDEGSVTEESSSEEIVEEEGSVIEESASEVIVEDEVS 649
Query: 4314 SGNHFIEDDVSEHSTTITGEEAIQNGQEEDKMIEGLEKVDADKDIGEPIIEKDGPDHSTT 4135
+ +ED+ S + E A+ +E ++ E +E D+ I + I++
Sbjct: 650 ASKEIVEDEASVTEEVVEEEGAV---SDEVQVTESVE----DEIINQGIVD--------- 693
Query: 4134 LGAELINDVHDEDKVNEGLERVGSDKDTGEPVIVEDVVPD--NSTRASGEKPIQDGHGEE 3961
E+I V E V + E V D+ E + VE+ V + T+ E+ + G E
Sbjct: 694 ---EVI--VEQEASVTD--EIVKEDESVIEEIAVEETVTEVVEETKPMDEEIVDQGSVVE 746
Query: 3960 KITERLEIDRTDKEIGEPTMEEGVVLDQSTTIGVEPVVDNYKEHKVTEGLEIIGENKDIG 3781
+ E+ TM+E +V DQ + VV+N +E K + E IG+ +
Sbjct: 747 NVEEK------------KTMDEEIV-DQGS------VVENVEEKKTMD--EEIGDQGSVA 785
Query: 3780 EPIIEENLVLDHSTTPIVEIKDGHEEDKVIEGSELAGAEDIGEPITEEDVSDHTTTTIGK 3601
E + EE LV T ++E + ED V E S E I EP+T + + T K
Sbjct: 786 EKVEEEELV----TEEVIEREGSINEDIVKEASITEEVEQI-EPVTGKVEKIESITDEIK 840
Query: 3600 EP--TKDVHEEDKAVAFSDLSSADQNFEQVNLSGQTECFEVENLNKHA------DASTTT 3445
E +D+ EE A N E+V ++ TE EVE K + +TT
Sbjct: 841 EQLVPEDIKEEQLDFEEIVAQRASVNDEKVEVASITE--EVEEEEKSVSEEVLEEEGSTT 898
Query: 3444 HQVIEDPVKEESDVLSQDRVHEE 3376
+V+E+ E V Q V EE
Sbjct: 899 EKVVEEGSSTEVVVEEQGSVSEE 921
Score = 120 bits (302), Expect = 4e-24
Identities = 250/1166 (21%), Positives = 483/1166 (41%), Gaps = 109/1166 (9%)
Frame = -3
Query: 6402 ITEKDVAPDHSIT--AFEEEPIKYVHEEDKVI---EGTEIIGADKD-------IGDPIIG 6259
+TEK V + S+T E+E +K EE +++ EG+ G +D + D ++
Sbjct: 2724 LTEKIVEEEKSVTEEVEEKESVKEEVEEQRLVVEEEGSATEGIVEDRLATEGIVDDILVT 2783
Query: 6258 EEIVPDHSTT--------TIRGEPIQDD--------HEEDKVTEELKIDGANKDIGEPSI 6127
EEIV D T +I E + D+ EE EE+ ++G + + +I
Sbjct: 2784 EEIVEDGLATDEFVEQQGSIIEEVLDDEGSVTEEIVEEEGSPNEEI-VEGVSVIEEDDNI 2842
Query: 6126 KDVVLDQSTSSIGETPAKDGHEEHKLVGADKDIGKTIIKENVIPDHPIKTIGEIKHDHEE 5947
+ V + S+ E K+G E ++ D + + KE + + ++ +G + + +
Sbjct: 2843 EPVSEEIVEGSVTEEMIKEGLENEVILDEDSITEEALEKEGSVSEEIVEEMGSLTEEIVD 2902
Query: 5946 DKVIEGLDIDCGNEDNGEPITEEDGVRGHSTKTTWEEPAKDGHEEKVTKGLEIVDTNKNC 5767
++ E + EE S + EE + E+V+ EIV+ ++
Sbjct: 2903 EE-----------RSTSEDMIEEGSA---SEEIIQEESQVEEVVEEVSVIDEIVEEDELD 2948
Query: 5766 GKPFIEDDVIPEHSTTITGEKAIRNGQEEDKVIEELEKVDAEENIGEPIIEKDVVPDHAT 5587
K +E+ E +T E+ + + +EE V EE+ + + E ++ E IIE+
Sbjct: 2949 TKEVVEEI---EFNT----EEVVEHKEEEGSVAEEIVQEEKEGSVNEEIIEE------VG 2995
Query: 5586 TLGEELI-NDVHDDDKVIEGFEIVGSDKDTGEPVIVEDVVPEHPTTTSGKESIKDGHXXX 5410
++ EE++ DV D+++++E ++ ++ E V +E V E
Sbjct: 2996 SITEEMVEQDVSDNEEIVEERSVI---EEAEENVWIEKEVEEE----------------- 3035
Query: 5409 XXXXXXXXVGADREIREPVIEEDIVPDLSTTTREEPIEDGHEKNKVIEGLEIASSDKENG 5230
G D E E + EED V + + EE + E K +E + E
Sbjct: 3036 ---------GLDNE--EVIDEEDSVSEQA----EEEVYINEEILKESSDVEDVKVENE-- 3078
Query: 5229 DPIIEEVVPDHSTTTIGKESTNDVHEEDKVVAGLDIVGVDKDIGEPVIKDDVVPDRSTTT 5050
++ E V + + +S + +EEDK + +V + + E V+ D+V +
Sbjct: 3079 --LMNEEVNEET------QSVAENNEEDKELDNY-VVEETESVTEEVVVDEVPNSKEVQE 3129
Query: 5049 IE---EEPIQDGQAENEVI--EGLEKVELDKDFGDPITEKDVAPDYSITTFDEETIKDVH 4885
IE EE ++DG ++++ +G E+ ++ G + + + SIT +E K+
Sbjct: 3130 IESIIEEIVEDGLTTDDLVGQQGSVIEEVVEEVGS--DSEGIVEEASIT--EEVEKKESV 3185
Query: 4884 EEDKVIEGAEIGG---DNDIGDPVIGEEVVPDNSTTTIRGEPIQDDHEED--KMRERLKI 4720
ED ++E + G + + + V+GEE + T G Q+ EED E +I
Sbjct: 3186 TEDILVEESVTGDILVEGSVTEEVVGEEKLVSEEIVTEEGSVAQEIVEEDAPATEEIDEI 3245
Query: 4719 DGANKDIVE---PTVKDVVLDQSTTT----IGETPVK---DGHGGHKVTAGLERVGADKD 4570
+ +++VE P +++V ++ + T GE+ V+ + G +E V A ++
Sbjct: 3246 ESVTEEVVEEEGPVDEEIVQEEGSVTEEIIQGESKVEEVVEEQGSENEEIFVEEVSASQE 3305
Query: 4569 I---------------------------------GEPITKENVVSDHPIKTIGDIKDDHE 4489
I +P+T+E VV++ T I+++
Sbjct: 3306 IVQNESGTEEILEKVSASQEIVQDGSVTEQIIEEQKPVTEE-VVNEEESITHEIIQEESH 3364
Query: 4488 EDKVIEGLDIGGNEDIGEPTIEDGISYHSTTTTWE-EPTKD-GHEEKVTEGLEIVDTDEN 4315
+KV++ + E +E+ +S E T+D G E V E EIV+ +E
Sbjct: 3365 VEKVVQ------QGSVAEEVVENPVSVTEEIVEKEGSVTEDIGQEGYVAE--EIVEEEEF 3416
Query: 4314 SGNHFIEDD-VSEHSTTITGEEAIQNGQEEDKMIEGLEKVDADKDIGEPIIEKDGP---- 4150
+E++ V+E EE N + + I E V + + E ++E++G
Sbjct: 3417 DNEEILEEESVAEEFV----EEGFDNEEIFVEQISDSEIVKEENSVNEEVLEEEGSYTEE 3472
Query: 4149 --DHSTTLGAELIND--------VHDEDKVNEG-LERVGSDKD---TGEPVIVEDVVPDN 4012
+ + E++ + + +E NE LE GS + E E+++ +
Sbjct: 3473 ILEEEGSYTEEILEEEGSFTEEILEEEGSYNEEILEEEGSYNEEILEEEGSFTEEILEEE 3532
Query: 4011 STRASGEKPIQDGHGEEKITERLEIDRTDKEIGEPTMEEGVVLDQSTTIGVEPVVDN--- 3841
++ + + G E+I E E TD +G+ ++ E V+ ++ + E V +N
Sbjct: 3533 G--SATDYFVGQGSDNEEIIE--EGSATDYFVGQGSIIEEVLEEEG--LDTEKVFENEGS 3586
Query: 3840 YKEHKVTEGL-EIIGENKDIGEPIIEENLVLDHSTTPIVEIKDGHEEDKVIEGSELAGAE 3664
E + TE E++ E + + E I+EE + E + IE E
Sbjct: 3587 ATEFEETESFTEVVEETESVNENILEETSI---------------NEVQKIESI----TE 3627
Query: 3663 DIGEPITEEDVSDHTTTTIGKEPTKDVHEEDKAVAFSDLSSADQNFEQVNLSGQTECFEV 3484
DI E + E++ + + E K+ + + + L S + EQ+ E +
Sbjct: 3628 DIKEQLVPEEIKEE---QLDSEEIKEEQLDSEEIKEEQLDSEEIKEEQL----VPEEIKE 3680
Query: 3483 ENLNKHADASTTTHQVIEDPVKEESDVLSQDRVHEEDGDNPKDEEDNVESFEMSKGQ--E 3310
E L+ Q++ + +KEE L+ + + EE D+ + +E+ ++S E+ + Q
Sbjct: 3681 EQLDSE---EIKEEQLVPEEIKEEQ--LNSEEIKEEQLDSEEIKEEQLDSEEIKEEQLDS 3735
Query: 3309 PAISHQEKTIAEATTLIQKSETESMK 3232
I Q+ ++ E + S TE +K
Sbjct: 3736 EEIKEQKGSVNEEVVEEEGSVTEEIK 3761
Score = 119 bits (299), Expect = 8e-24
Identities = 224/1097 (20%), Positives = 446/1097 (40%), Gaps = 44/1097 (4%)
Frame = -3
Query: 6399 TEKDVAPDHSITAFEEEPIKYVHEEDKVIEGTEIIGADKDIGDPIIGEEIVPDHSTTTIR 6220
TEK + S T FEE +V+E TE + E I+ + S ++
Sbjct: 3577 TEKVFENEGSATEFEE-----TESFTEVVEETESVN-----------ENILEETSINEVQ 3620
Query: 6219 G-EPIQDDHEEDKVTEELKIDGANKDIGEPSIKDVVLDQSTSSIGETPAKDGHEEHKLVG 6043
E I +D +E V EE+K + + IK+ LD + +++ EE +
Sbjct: 3621 KIESITEDIKEQLVPEEIK----EEQLDSEEIKEEQLDSEEIKEEQLDSEEIKEEQLVPE 3676
Query: 6042 ADKDI---GKTIIKENVIPDHPIKTIGEIKHDHEEDKVIEGLDIDCGNEDNGEPITEEDG 5872
K+ + I +E ++P+ EIK + + I+ +D E I EE
Sbjct: 3677 EIKEEQLDSEEIKEEQLVPE-------EIKEEQLNSEEIKEEQLD------SEEIKEEQ- 3722
Query: 5871 VRGHSTKTTWEEPAKDGHEEKVTKGLEIVDTNKNCGKPFIEDDVIPEHSTTITGEKAIRN 5692
+E D E K KG + ++V+ E + K
Sbjct: 3723 ----LDSEEIKEEQLDSEEIKEQKGS-------------VNEEVVEEEGSVTEEIKE--- 3762
Query: 5691 GQEEDKVIEELEKVDAEENIGEPIIEKDVVPDHATTLGEELINDVHDDDKVIEGFEIVGS 5512
QEE E LE+V+ E+I E I+E + +E+I + D +V+E E++ S
Sbjct: 3763 -QEESVNEEVLEEVEETESIKEEIVEGGIAT-------QEIIEEESDTKEVVEE-EVIDS 3813
Query: 5511 DKDTGEPVIVEDVVPEHPTTTSGKESIKDGHXXXXXXXXXXXVGADREIREPVIEEDIVP 5332
+K + +V+PE + T E +++G + + E V+E+ +
Sbjct: 3814 EKLVDAGSVTGEVMPEEVSVTD--EVVEEGSTTEEVLEE------QKSVNEEVVEDGLTI 3865
Query: 5331 D-----LSTTTREEPIEDGHEKNKVIEGLEIASSDKENGDPIIEEVVPDHSTTTIGKEST 5167
D +TT E EDG K++E E + E++V E
Sbjct: 3866 DDFVGLQGSTTEEVVEEDGSAIEKILEEETATEEIVEKQVSVTEDIV----------EKE 3915
Query: 5166 NDVHEEDKVVAGLDIVGVDKDIGEPVIKDDVVPDRSTTTIEEEPIQDGQAENEVI--EGL 4993
V+EE I E + ++++ S T EE Q+ A EVI EGL
Sbjct: 3916 GSVNEEI--------------IEEASVAEEIIQGGSFT--EEIVGQEESATEEVIDEEGL 3959
Query: 4992 EKVELDKDFGDPITEKDVAPDYSITTFDEETIKDVHEEDKVIEGAEIGGDNDIGDPVIGE 4813
E++++ +TE+ + ++ DE +++V ++++E + ++ +
Sbjct: 3960 ISNEIEEEEEKSVTEEMIEEVEEVSVDDE--VEEVSVAEEIVE-----------EELVDD 4006
Query: 4812 EVVPDNSTTTIRGEPIQDDHEEDKMRERLKIDGANKDIVEPTVKDVVLDQSTTT----IG 4645
E++P+ + T ED + E + ++ + E +V + +L+Q + +
Sbjct: 4007 EILPEELSAT-----------EDVIEEVRSV--TDEIVQEESVCEEILEQEVSASEEYVD 4053
Query: 4644 ETPVKDGHGGHKVTAGLERVGADKDIGEPITKENVVSDHPIKTIGDIKDDHEEDKVIEGL 4465
+ V D GH+ V D + E +T+E D + K ++++E
Sbjct: 4054 DKSVTDDFVGHE-----RSVIQDVENTESVTEEIAEVDKSVIEEAVEKQGSVTEEIVEEE 4108
Query: 4464 DIGGNEDIGEPTIEDGISYHSTTTTWEEPTKDGHEEKVTEGLEIVDTDENSGNHFIEDDV 4285
++ E + + ++ + + E K+ E+V E + + D+ + +I ++
Sbjct: 4109 ELDTEEVLEDKSVTGDVVEQEGSGKDESEAKESFTEEVDELKSVKEEDQET--EYISREI 4166
Query: 4284 SEHSTTITGEEAIQNGQEEDKMIEGLEK-VDADKDIGEPIIEKDGPDHSTTLGAELINDV 4108
E S T E + +E E L K ++ +K + I+E+ + ++ E++ +
Sbjct: 4167 EEESATEQHSEQELSINKEVVETESLTKDIEEEKSTTQEILEE-----TQSVNEEIVEEE 4221
Query: 4107 HDEDKV--------NEGLERVGSDKD--------TGEPVIVEDVVPDNSTRASG---EKP 3985
D D+V E +E S + T E V VED+ + G E+
Sbjct: 4222 RDTDEVLKEKVSPSEEVIEEQASTTEEFLEERSSTDEIVEVEDLFTEEVKEREGSVTEEI 4281
Query: 3984 IQDGHGEEKITERLEIDRTDKEIGEPTMEEGVVLDQSTTIGVEPVVDNYKEHKVTEGLEI 3805
+++G +I E D ++ + E + E +V ++ + + + + VTE E
Sbjct: 4282 VEEGSDTGEIVEEEGSD-AEEILEEGSFNEEIVEEEGS------ITEEILQGSVTE--EF 4332
Query: 3804 IGENKDIGEPIIE-----ENLVLDHSTTPIVEIKDGHEEDKVIEGSELAGAEDIGEPITE 3640
+G+ + E I+E E V D S T V+ ++ E V+E E++ ++++ E E
Sbjct: 4333 VGQQGSVIEEIVETESAIEERVEDESATEEVDERESVTE--VVE-EEVSSSDEVVEGSIE 4389
Query: 3639 EDVSDHTTTT---IGKEPTKDVHEEDKAVA-FSDLSSADQNFEQVNLSGQTECFEVENLN 3472
E + + + T + E + D + +AV+ ++ + E+V ++ E+ ++
Sbjct: 4390 EVIENEGSVTEEILEHEVSADENFVGQAVSVIEEVEGTESVTEEVVEETESVSEEIVEVS 4449
Query: 3471 KHADASTTTHQVIEDPVKEESDVLSQDRVHEEDGDNPKDEEDNVESFEMSKGQEPAISHQ 3292
+ T VIE+ V+++ +++ E GD+ +E + + + E+ GQ+ + +
Sbjct: 4450 PTENVVQQTDSVIEEDVEQKEGSFNEEIDIRELGDDGVEEREKISTEEV-VGQDKSATGD 4508
Query: 3291 EKTIAEATTLIQKSETE 3241
+ + + + S TE
Sbjct: 4509 VEESSSTGDVEEVSSTE 4525
Score = 116 bits (291), Expect = 7e-23
Identities = 243/1235 (19%), Positives = 498/1235 (40%), Gaps = 161/1235 (13%)
Frame = -3
Query: 6420 KDIGEPITEKDVAPDHSITAFEEEPIKYVHEE----DKVIEGTEIIGADKDIGDPIIGEE 6253
K + E I E D++ + I ++V EE DK++E + K++G+ + +
Sbjct: 1009 KSVNEEIEETDLSTEEIIKQQGLATYEFVEEEKSLTDKLLEEESVT---KEVGETELSTQ 1065
Query: 6252 IVPDHSTTTIRGEPIQDDH-------EEDKVTEELKIDGANKDI------------GEPS 6130
V D + + E I+++ EE TEE+ +G+ +I E S
Sbjct: 1066 EVVDEKVS-VTEEVIEEEKSVSEEVLEEGSATEEVVEEGSCTEIVVEKGSDTEIVVEEGS 1124
Query: 6129 IKDVVLDQSTSSIGETPAKDGHEEHKLVGADKDIGKTIIKENVIPDHPIKTIGEIKHDHE 5950
++V+++ +++ E ++G +++ + + +++E + D+ K+ G I++ E
Sbjct: 1125 ATEIVVEEGSAT--EVVVEEGSVSEEMLEEEGSATEEVVEEGLSSDNVQKSKGVIENVGE 1182
Query: 5949 --------EDKVIEGLDIDC------------GNEDNG--EPITEEDGVRGHST--KTTW 5842
++ + E + ++ G DN E + ED + H+ +T
Sbjct: 1183 IYSVKTAKDESMNEKIPLEKSSFVDDESFKGQGPTDNVSVEDVNSEDIINEHTPLEETKI 1242
Query: 5841 EE------PAKDGHE------------EKVTKGLEI-------VDTNKNCGKPFIEDDVI 5737
EE D H EK+ + +E + N + + +D++
Sbjct: 1243 EELPTEYITTADIHTRGETETKYNLIYEKINEEVEKAKFQEEKITENIPVERESVTEDIV 1302
Query: 5736 PEHSTTITGEKAIRNGQEEDKVIEELEKVDAEENIGEPIIEKDVVPDHATTLGEELINDV 5557
E S E+ + E ++ EK+ E ++ E ++EK+ + +E I +
Sbjct: 1303 QEPSLAQEVEQKESDTNEIEETKLANEKIIPEVSVTENVVEKEGLDTEEVLEEDESITEE 1362
Query: 5556 HDDDKVIEGFEIVGSDKDTGEPVI------VEDVVPEHPTTT--------SGKESIKDGH 5419
+++V EIV ++ + E ++ E++V E +++ S E I +
Sbjct: 1363 IVEEEVSACEEIVEEEESSSEEIVEEEESSSEEIVEEEESSSEEIVEEEESSSEEIVEEE 1422
Query: 5418 XXXXXXXXXXXVGADR------EIREPVIEEDI-----VPDLSTTTREEPIEDGH----- 5287
+ + E ++EE++ V D+ + + E E+G
Sbjct: 1423 ESSSEEIIEEVSSTEEVLEEEGSVTEEIVEEEVSTTEEVKDIGSVSEEVLEEEGFGTEEF 1482
Query: 5286 --EKNKVIEGLEIASSDKE--------NGDPIIEEVVPDHSTTTIGKESTNDVHEEDKVV 5137
++ VIE + S E N + I++E P + ST + H+E
Sbjct: 1483 VGQQGSVIEEIVETESSTEKVLEDVGSNVEEIVQEEGPVAQEIVHEEVSTTEKHDEVDRS 1542
Query: 5136 AGLDIVGVDKDIGEPVIKDDVVPDRSTTTIEEEPIQDGQAENEVIEG---LEKVELDKDF 4966
+IV + E +I ++V + EE +++G EV+E + +V +
Sbjct: 1543 TTEEIVEKVGSVSEEIIVEEV-------SASEEIVEEGSVTEEVVEEEKLINEVGETESV 1595
Query: 4965 GDPITEKDVAPDYSITTFDEETIKDVHEEDKVIEGAEIGGDNDIGDPVIG---------E 4813
+ I +K+V+ + + +++ E++ ++E +G + + + ++ E
Sbjct: 1596 TEEIVQKEVSDAEEVLGQEGSMNEEILEKESIVEEI-VGPEGSVTEEIVDYGSFAEEVKE 1654
Query: 4812 EVVPDNSTTTIRGEPIQDDHEEDKMRERLKI-DGANKDIVE---PTVKDVVLDQSTTT-- 4651
E + G ++ EE+ + E I + A +I+E P ++V ++ T
Sbjct: 1655 EELVTEEAVQYEGSVTEEIKEEESITENEAIEESAFAEIIEEKGPNNDEIVKEEGLDTEE 1714
Query: 4650 -IGETPVKDGHGGHKVTAGLERVGADKDIGEPIT-KENVVSDHPIKTIGDIKDDHEEDKV 4477
+ E V D E + +K + E I +E V++ P+ +++ ED V
Sbjct: 1715 IVNEVSVTD-----------EVIEEEKLVNEQIVGEERSVTEKPV----EVERSATEDLV 1759
Query: 4476 IEGLDIGGNEDIGEPTIEDGISYHSTTTTWEEPTKDGHEEKVTEGLEIVDTDENSGNHFI 4297
EG ++ + +S H +T T+ +E V E EIV+ + + + I
Sbjct: 1760 EEG-----------ASVTEKVSVHEGST-----TEQILDESVAE--EIVEEEVSVDDKII 1801
Query: 4296 EDDVSEHSTTITGEEAIQNGQEEDKMIEGLEKVDADKDIGEPIIEKDGPDHSTTLGAELI 4117
E++VS +EE +IE E V+ ++ + E I+E++ L E +
Sbjct: 1802 EEEVSVDEVV----------EEEGSVIE--EIVEEEESVPEEILEEELSGSEEVLEDEWV 1849
Query: 4116 ND--VHDEDKVNEGLERVGSDKDTGEPVIVEDVVPDNSTRASGEKPIQDGHGEEKITERL 3943
D + E V E +E + GE I E++V +DG EKI E
Sbjct: 1850 TDAFMGQEGSVIEEIEEIVD----GEGSITEEIV-------------EDGSANEKIVEE- 1891
Query: 3942 EIDRTDKEIG------EPTMEEGVVLDQSTTIGVEPVVDNYKEHKVTEGLEIIGENKDIG 3781
E R ++ +G E +EEG V++Q + V + +E E ++ + E + I
Sbjct: 1892 EPSRVEEVLGKEGFVIEEIIEEGSVIEQ--VEDTKTVSEKSEESSAIEEVKEVKEEESIS 1949
Query: 3780 EPIIEENLVLDHSTTPIVEIKDGHEEDKVIEGSELAGAEDIGE---PITEEDVSDHTTTT 3610
E I+E+ + S T + ++ +K+++ +++ ED E +TE+ + + T
Sbjct: 1950 EKIVEK----EESVTEEIVRQEESTTEKIVK--DVSPTEDFVEQTDSVTEKVIEQEGSNT 2003
Query: 3609 IGKEPTKDVHEEDKAVAFSDLSSADQNFEQVNLSGQTECFEVENLNKHADASTTTHQVIE 3430
E +DV E++ A S + E V+++ Q C + + D + T +++E
Sbjct: 2004 ---EVAEDVEEKESA-------SDEHEQEDVSVNAQVTCEKKSVTKEIVDEVSRTEEIVE 2053
Query: 3429 D--PVKEESD--------VLSQDRVHEEDGDNPKDEEDNVESFEMSKGQEPAISHQEKTI 3280
+ V E D ++ + V EE ++ E+ VE + + S E+ +
Sbjct: 2054 ENGSVTEGVDETGSVTEEIIEEATVTEEVVEDGSVTEEVVEDGSVIQEVVEDGSVTEEIV 2113
Query: 3279 AEATTLIQKSETESMKLNR--------TGEPDSTE 3199
E ++ ++ E +N +GE D TE
Sbjct: 2114 QENGSVTEEIVEEEGSVNEEVEEEVSVSGEVDETE 2148
Score = 115 bits (289), Expect = 1e-22
Identities = 194/968 (20%), Positives = 397/968 (41%), Gaps = 86/968 (8%)
Frame = -1
Query: 3116 VKESDLVSIEEATDSTQE-TEIVTLEEETPKNSLNDFRATEAPLEEITKMKKSDKLNYTP 2940
VKE + EE T+ Q T+ + +EE + +++ + + E +
Sbjct: 475 VKEESV--FEELTEEDQSVTKEIPVEEHSVFKEVDEIESVTEEIVEEEGSVNEEVEEEVS 532
Query: 2939 TESAMSEEQVIKEIPEKTESANHETIFVTQPTEKLSLHEAEPQGGELVDASDDASVEMFS 2760
+ E + + E E+TE N E + + + E ++V+ + E S
Sbjct: 533 VSGEVDETEYVTEEVEETELVNEEVLKEEGSASEKVVKEEGSASEKIVEEEGSVTEETAS 592
Query: 2759 TPI-EEHGASSLDPDMEDVKQGEIATLDDNATDNTFTAENAETEHEKPEVPVENSAVATQ 2583
I EE G+ + + E++ + E + ++++++ E + E EV VE+ A++
Sbjct: 593 EEIVEEEGSVTEESSSEEIVEDEGSVTEESSSEEIVEEEGSVIEESASEVIVEDEVSASK 652
Query: 2582 SVDKDTQTTLVSEITASKASSDDLSEEKPQKSSMLISAKNEFNAVGMKEK--IKEECQID 2409
+ +D + + A SD++ + S ++E G+ ++ +++E +
Sbjct: 653 EIVEDEASVTEEVVEEEGAVSDEVQVTE--------SVEDEIINQGIVDEVIVEQEASVT 704
Query: 2408 DEI---KDKKMEAPLVAQTKGEVNMQTEEHLNLEKDSEMGIENTEQKISVXXXXXXXXXX 2238
DEI + +E V +T EV +T+ D +EN E+K ++
Sbjct: 705 DEIVKEDESVIEEIAVEETVTEVVEETKPMDEEIVDQGSVVENVEEKKTM---------- 754
Query: 2237 EQKDADVSLEREKIIELNEYKENNRSETSDSGLKETKFESEEEFDACSKELETTGTCANI 2058
D ++ +++ ++E E K+ E D G K E EE + +E G +I
Sbjct: 755 ---DEEI-VDQGSVVENVEEKKTMDEEIGDQGSVAEKVEEEEL--VTEEVIEREG---SI 805
Query: 2057 ETDILEQEEDALKKLDQNLESEKGTM-KVEEIQVEVKATDHSHKINE-----SHNTAESA 1896
DI+ +E ++ + + +E G + K+E I E+K I E A+ A
Sbjct: 806 NEDIV--KEASITEEVEQIEPVTGKVEKIESITDEIKEQLVPEDIKEEQLDFEEIVAQRA 863
Query: 1895 LLAQDNLEAIDPCDEIKRDTESTDHDQSKEALSEIEK-------TEVVEDKEIMKYQNVV 1737
+ + +E +E++ + +S + +E S EK TEVV +++ + V+
Sbjct: 864 SVNDEKVEVASITEEVEEEEKSVSEEVLEEEGSTTEKVVEEGSSTEVVVEEQGSVSEEVL 923
Query: 1736 SVEDHTVGESIQDEENENDSLDEAG-------PKLNANDQNDDMNDVNPPIKDAIVNEEM 1578
E T E ++++ + ++L E K D+ D + D N K+ V E++
Sbjct: 924 EEEGSTTEEVVEEQGSVTENLLEEESASQGIVEKEEFVDEEDSVKDQNVFEKEGSVTEQL 983
Query: 1577 ---PHGVERADNGREETLVGEVGEQCK--------VDPNFESDLQNEG------------ 1467
G+ DN +EE L+ E+ E+ K D + E ++ +G
Sbjct: 984 VEEEKGLINEDNEKEE-LITEMSEEIKSVNEEIEETDLSTEEIIKQQGLATYEFVEEEKS 1042
Query: 1466 -ADKGNDEEDKCRKLDAXXXXXXXXXXXXXXVGKQLEEESDLVPGELINE-IVTNRTENE 1293
DK +EE +++ V +++ EE V E++ E T E
Sbjct: 1043 LTDKLLEEESVTKEVGETELSTQEVVDEKVSVTEEVIEEEKSVSEEVLEEGSATEEVVEE 1102
Query: 1292 GGAP----KDTTDTDGVIDVNKPAESTF--STNTTSTIEKLHIDEKLLTDNPDASSLT-- 1137
G + +DT+ V++ E + T +E+ + E++L + A+
Sbjct: 1103 GSCTEIVVEKGSDTEIVVEEGSATEIVVEEGSATEVVVEEGSVSEEMLEEEGSATEEVVE 1162
Query: 1136 -EASQESMQEKEGKNTEDGEKQEVVFVKKATKDMGLPTEESR----ENIEHEAPVAEMSK 972
S +++Q+ +G GE V K + + +P E+S E+ + + P +S
Sbjct: 1163 EGLSSDNVQKSKGVIENVGEIYSVKTAKDESMNEKIPLEKSSFVDDESFKGQGPTDNVSV 1222
Query: 971 EGGKK---INEVSIEEKSFRNEEGETQVLKQPD--------TPRDL--QMLDQSSDVTAE 831
E INE + E++ + EE T+ + D T +L + +++ +
Sbjct: 1223 EDVNSEDIINEHTPLEET-KIEELPTEYITTADIHTRGETETKYNLIYEKINEEVEKAKF 1281
Query: 830 QEASIETDSIEKTKENISIGSIEIPSAPVDVIEKSLQTAEVEEGK--------HGEVQGN 675
QE I T++I +E+++ ++ PS +V +K T E+EE K V N
Sbjct: 1282 QEEKI-TENIPVERESVTEDIVQEPSLAQEVEQKESDTNEIEETKLANEKIIPEVSVTEN 1340
Query: 674 DSELNTVECEASFDEETNTNSKSSEAKGASLFDLLNKPRKDTGQAVEQFEEEGNSTSNKE 495
E ++ E +E+ + + E + ++ +++ + + + VE+ E +E
Sbjct: 1341 VVEKEGLDTEEVLEEDESITEEIVEEEVSACEEIVEEEESSSEEIVEEEESSSEEIVEEE 1400
Query: 494 QLENKEVL 471
+ ++E++
Sbjct: 1401 ESSSEEIV 1408
Score = 115 bits (287), Expect = 2e-22
Identities = 235/1177 (19%), Positives = 458/1177 (38%), Gaps = 111/1177 (9%)
Frame = -3
Query: 6438 ENVDLDKDIGEPITEKDVAPDHSITAFEEEPIKYVHEEDKVIE--------GTEIIGADK 6283
EN + DK++ + E+ + + E K V E + +IE +++G
Sbjct: 3093 ENNEEDKELDNYVVEETESVTEEVVVDEVPNSKEVQEIESIIEEIVEDGLTTDDLVGQQG 3152
Query: 6282 DIGDPIIGEEIVPDHSTTTIRGEPIQDDHEEDKVTEELKIDGA--NKDIGEPSIKDVVLD 6109
+ + ++ EE+ D ++ +++ VTE++ ++ + + E S+ + V+
Sbjct: 3153 SVIEEVV-EEVGSDSEGIVEEASITEEVEKKESVTEDILVEESVTGDILVEGSVTEEVVG 3211
Query: 6108 QSTSSIGETPAKDGHEEHKLVGADKDIGKTIIKENVIPDHPIKTIGEIKHD--HEEDKVI 5935
+ E ++G ++V D + I + + + ++ G + + EE V
Sbjct: 3212 EEKLVSEEIVTEEGSVAQEIVEEDAPATEEIDEIESVTEEVVEEEGPVDEEIVQEEGSVT 3271
Query: 5934 EGLDIDCGNEDNGEPITEEDGVRGH---------STKTTWEEPAKDGHEEKVTKGLEIVD 5782
E + E E + EE G S + E + EKV+ EIV
Sbjct: 3272 EEI---IQGESKVEEVVEEQGSENEEIFVEEVSASQEIVQNESGTEEILEKVSASQEIVQ 3328
Query: 5781 TNK------NCGKPFIEDDVIPEHSTT-------ITGEKAIRNGQEEDKVIEE------- 5662
KP E+ V E S T EK ++ G ++V+E
Sbjct: 3329 DGSVTEQIIEEQKPVTEEVVNEEESITHEIIQEESHVEKVVQQGSVAEEVVENPVSVTEE 3388
Query: 5661 --------LEKVDAEENIGEPIIEKDVVPD----HATTLGEELINDVHDDDKV----IEG 5530
E + E + E I+E++ + ++ EE + + D++++ I
Sbjct: 3389 IVEKEGSVTEDIGQEGYVAEEIVEEEEFDNEEILEEESVAEEFVEEGFDNEEIFVEQISD 3448
Query: 5529 FEIVGSDKDTGEPVI------VEDVVPEHPTTT--------SGKESIKDGHXXXXXXXXX 5392
EIV + E V+ E+++ E + T S E I +
Sbjct: 3449 SEIVKEENSVNEEVLEEEGSYTEEILEEEGSYTEEILEEEGSFTEEILEEEGSYNEEILE 3508
Query: 5391 XXVGADREI--REPVIEEDIVPDLSTTT---------REEPIEDGHEKNKVI-------- 5269
+ EI E E+I+ + + T EE IE+G + +
Sbjct: 3509 EEGSYNEEILEEEGSFTEEILEEEGSATDYFVGQGSDNEEIIEEGSATDYFVGQGSIIEE 3568
Query: 5268 ----EGLEIASSDKENGDPIIEEVVPDHSTTTIGKESTND-VHEEDKVVAGLDIVGVDKD 5104
EGL+ + G E + ES N+ + EE + I + +D
Sbjct: 3569 VLEEEGLDTEKVFENEGSATEFEETESFTEVVEETESVNENILEETSINEVQKIESITED 3628
Query: 5103 IGEPVIKDDVVPDRSTTTIEEEPIQDGQAENEVIEGLEKVELDKDFGDPITEKDVAP-DY 4927
I E ++ +++ ++ ++ E I++ Q ++E I ++ +LD + I E+ + P +
Sbjct: 3629 IKEQLVPEEIKEEQ----LDSEEIKEEQLDSEEI---KEEQLD---SEEIKEEQLVPEEI 3678
Query: 4926 SITTFDEETIKDVHEEDKVIEGAEIGGDNDIGDPVIGEEVVPDNSTTTIRGEPIQDDHEE 4747
D E IK+ + I+ ++ + +I + + E + + + + Q D EE
Sbjct: 3679 KEEQLDSEEIKEEQLVPEEIKEEQLNSE-EIKEEQLDSEEIKEEQLDSEEIKEEQLDSEE 3737
Query: 4746 DKMRERLKIDGANKDIVEP--TVKDVVLDQSTTTIGETPVKDGHGGHKVTAGLERVGADK 4573
K ++ N+++VE +V + + +Q + E LE V +
Sbjct: 3738 IKEQK----GSVNEEVVEEEGSVTEEIKEQEESVNEEV--------------LEEVEETE 3779
Query: 4572 DIGEPITKENVVSDHPIKTIGDIKDDHEE-----DKVIEGLDIGGNEDIGEPTIEDG-IS 4411
I E I + + + I+ D K+ EE +K+++ + G E ++ D +
Sbjct: 3780 SIKEEIVEGGIATQEIIEEESDTKEVVEEEVIDSEKLVDAGSVTGEVMPEEVSVTDEVVE 3839
Query: 4410 YHSTTTTWEEPTKDGHEEKVTEGLEI---VDTDENSGNHFIEDDVSEHSTTITGEEAIQN 4240
STT E K +EE V +GL I V ++ +E+D S AI+
Sbjct: 3840 EGSTTEEVLEEQKSVNEEVVEDGLTIDDFVGLQGSTTEEVVEEDGS----------AIEK 3889
Query: 4239 GQEEDKMIEGLEKVDADKDIGEPIIEKDGPDHSTTLGAELINDVHDEDKVNEG----LER 4072
EE+ E E V+ + E I+EK+G ++ E+I + +++ +G E
Sbjct: 3890 ILEEETATE--EIVEKQVSVTEDIVEKEG-----SVNEEIIEEASVAEEIIQGGSFTEEI 3942
Query: 4071 VGSDKDTGEPVIVEDVVPDNSTRASGEKPIQDGHGEEKITERLEIDRTDKEIGEPTMEEG 3892
VG ++ E VI E+ + N EK + E++ E +E D E+ E ++ E
Sbjct: 3943 VGQEESATEEVIDEEGLISNEIEEEEEKSV-----TEEMIEEVEEVSVDDEVEEVSVAEE 3997
Query: 3891 VVLDQSTTIGVEPVVDNYKEHKVTEGLEIIGENKDIGEPIIEENLVLDHSTTPIVEIKDG 3712
+V ++ + P +E TE ++I E + + + I++E V + V +
Sbjct: 3998 IVEEELVDDEILP-----EELSATE--DVIEEVRSVTDEIVQEESVCEEILEQEVSASEE 4050
Query: 3711 HEEDKVIEGSELAGAEDIGEPITEEDVSDHTTTTIGKEPTKDVHEEDKAVAFSDLSSADQ 3532
+ +DK +T++ V + E T+ V EE +A D S ++
Sbjct: 4051 YVDDK---------------SVTDDFVGHERSVIQDVENTESVTEE---IAEVDKSVIEE 4092
Query: 3531 NFEQVNLSGQTECFEVENLNKHADASTTTHQVIEDPVKEESDVLSQDRVHEEDGDNPKDE 3352
E+ S E E E L+ T +V+ED DV+ Q+ +++ + +
Sbjct: 4093 AVEKQG-SVTEEIVEEEELD--------TEEVLEDK-SVTGDVVEQEGSGKDESEAKESF 4142
Query: 3351 EDNVESFEMSKGQEPAISHQEKTIAEATTLIQKSETE 3241
+ V+ + K ++ + + I E + Q SE E
Sbjct: 4143 TEEVDELKSVKEEDQETEYISREIEEESATEQHSEQE 4179
Score = 95.5 bits (236), Expect = 2e-16
Identities = 199/914 (21%), Positives = 375/914 (41%), Gaps = 38/914 (4%)
Frame = -1
Query: 3113 KESDLVSIEEATDSTQET--EIVTLEEETPKNSLNDFRATEAPLEEITKMKKSDKLNYTP 2940
KESD IEE + ++ E+ E K L+ TE LEE +
Sbjct: 1314 KESDTNEIEETKLANEKIIPEVSVTENVVEKEGLD----TEEVLEEDESI---------- 1359
Query: 2939 TESAMSEE-QVIKEIPEKTESANHETIFVTQPTEKLSLHEAEPQGGELVDASDDASVEMF 2763
TE + EE +EI E+ ES++ E + + + + + E E E+V+ + +S E+
Sbjct: 1360 TEEIVEEEVSACEEIVEEEESSSEEIVEEEESSSEEIVEEEESSSEEIVEEEESSSEEI- 1418
Query: 2762 STPIEEHGASSLDPDMEDVKQGEIATLDDNATDNTFTAENAETEHEKPEVPVENSAVATQ 2583
+EE +SS + E E+ + + T+ E + TE K V + +
Sbjct: 1419 ---VEEEESSSEEIIEEVSSTEEVLEEEGSVTEEIVEEEVSTTEEVKDIGSVSEEVLEEE 1475
Query: 2582 SVDKDT----QTTLVSEITASKASSDDLSEEKPQKSSMLISAKNEFNAVGMKEKIKEECQ 2415
+ Q +++ EI +++S++ + E+ ++E ++EE
Sbjct: 1476 GFGTEEFVGQQGSVIEEIVETESSTEKVLEDVGSN---------------VEEIVQEEGP 1520
Query: 2414 IDDEIKDKKMEAPLVAQTKGEVNMQTEEHLNLEKDSEMGIENTEQKISVXXXXXXXXXXE 2235
+ EI +++ + EV+ T E + +EK + E +++S
Sbjct: 1521 VAQEIVHEEVST---TEKHDEVDRSTTEEI-VEKVGSVSEEIIVEEVSASEEIVEEGSVT 1576
Query: 2234 QKDADVSLEREKIIELNEYKENN-------RSETSDSG--LKETKFESEEEFDACSKELE 2082
++ +E EK+I NE E + E SD+ L + +EE + S E
Sbjct: 1577 EE----VVEEEKLI--NEVGETESVTEEIVQKEVSDAEEVLGQEGSMNEEILEKESIVEE 1630
Query: 2081 TTGTCANIETDILEQEEDALKKLDQNLESEKGTMKVEEIQVEVKATDHSHKINESHNTAE 1902
G ++ +I++ A + ++ L +E+ + E+K + I E+ E
Sbjct: 1631 IVGPEGSVTEEIVDYGSFAEEVKEEELVTEEAVQYEGSVTEEIKEEE---SITENEAIEE 1687
Query: 1901 SALLAQDNLEAIDPC-DEIKRDTESTDHDQSKEALSEIEKTEVVEDKEIMKYQNVVSVED 1725
SA + +E P DEI ++ E D ++E ++E+ T+ V ++E + + +V E
Sbjct: 1688 SAFA--EIIEEKGPNNDEIVKE-EGLD---TEEIVNEVSVTDEVIEEEKLVNEQIVGEER 1741
Query: 1724 HTVGESIQDEENENDSLDEAGP----KLNANDQNDDMNDVNPPIKDAIVNEEMPHGVERA 1557
+ ++ E + + L E G K++ ++ + ++ + + IV EE+ +
Sbjct: 1742 SVTEKPVEVERSATEDLVEEGASVTEKVSVHEGSTTEQILDESVAEEIVEEEVSVDDKII 1801
Query: 1556 DNGREETLVGEVGEQCKVDPNFESDLQNEGADKGNDEEDKCRKLDAXXXXXXXXXXXXXX 1377
+ EE V EV E+ E ++ E + E++ +
Sbjct: 1802 E---EEVSVDEVVEE--EGSVIEEIVEEEESVPEEILEEELSGSEEVLEDEWVTDAFMGQ 1856
Query: 1376 VGKQLEEESDLVPGE--LINEIVTNRTENEGGAPKDTTDTDGVIDVNKPAESTFSTNTTS 1203
G +EE ++V GE + EIV + + NE ++ + + V+ S
Sbjct: 1857 EGSVIEEIEEIVDGEGSITEEIVEDGSANEKIVEEEPSRVEEVLGKEGFVIEEI-IEEGS 1915
Query: 1202 TIEKLHIDEKLLTDNPDASSLTE---------ASQESMQEKEGKNTEDGEKQEVVFVKKA 1050
IE++ D K +++ + SS E + E + EKE TE+ +QE +K
Sbjct: 1916 VIEQVE-DTKTVSEKSEESSAIEEVKEVKEEESISEKIVEKEESVTEEIVRQEESTTEKI 1974
Query: 1049 TKDMGLPTEESRENIEHEAPVAE--MSKEGGKKINEVSIEEKSFRNEEGETQVLKQPDTP 876
KD+ PTE+ +E V E + +EG +EEK ++E E Q D
Sbjct: 1975 VKDVS-PTEDF---VEQTDSVTEKVIEQEGSNTEVAEDVEEKESASDEHE-----QEDVS 2025
Query: 875 RDLQMLDQSSDVTAE--QEASIETDSIEKTKENISIGSIEIPSAPVDVIEKSLQTAE-VE 705
+ Q+ + VT E E S T+ I + +++ G E S ++IE++ T E VE
Sbjct: 2026 VNAQVTCEKKSVTKEIVDEVS-RTEEIVEENGSVTEGVDETGSVTEEIIEEATVTEEVVE 2084
Query: 704 EGK-HGEVQGNDSELNTVECEASFDEETNTNSKSSEAKGASLFDLLNKPRKDTGQAVEQF 528
+G EV + S + V + S EE + S + + ++ G E+
Sbjct: 2085 DGSVTEEVVEDGSVIQEVVEDGSVTEEIVQENGS----------VTEEIVEEEGSVNEEV 2134
Query: 527 EEEGNSTSNKEQLE 486
EEE + + ++ E
Sbjct: 2135 EEEVSVSGEVDETE 2148
Score = 95.1 bits (235), Expect = 2e-16
Identities = 207/969 (21%), Positives = 368/969 (37%), Gaps = 90/969 (9%)
Frame = -1
Query: 3104 DLVSIEEATDSTQETEIVT----LEEETPKNSLNDFRATEAPLEEITKMKKSDKLNYTPT 2937
+ V +E T E EI+ EE+T + E+P+EE+ K+N
Sbjct: 48 EFVQEKELNQETLENEIIVDHIKEEEDTRNVKEQESVLEESPIEELPVENNIGKINEEVE 107
Query: 2936 ESAMS----EEQVIKEIP-EKTESANHETIFVTQ--PTEKLSLHEAEPQGGELVDASDDA 2778
E ++ EEQV KE+P E+ E E + + + +E+ ++ E + G+L++
Sbjct: 108 EFILNEIPLEEQVPKELPQEEIEEIVVEELPIDEHLSSEETTVTEEDTFKGQLINEEKPV 167
Query: 2777 SVEMFS--TPIEEHGASSLDPDMEDVKQGEIATLDDNATDNTFTAENAETEHEKPEVPVE 2604
+ S P+EE S P E EI + N ++ E +E E+PVE
Sbjct: 168 EEKSVSEEIPVEEKSVSEEIPVEEKSVSEEIPVEEKNVSEEIPVEEKNVSE----EIPVE 223
Query: 2603 NSAVATQ---SVDKDTQTTLVSEITASK---ASSDDLSEEKPQKSSMLISAKNEFNAVGM 2442
V+ + + ++ V E S+ +++SEE P+ + +
Sbjct: 224 EKNVSEEIPVEEENVSEEIPVEEENVSEEIPVEEENVSEEIPEGGIAIEDVPVD------ 277
Query: 2441 KEKIKEECQIDDEIKDK--------KMEAPLVAQTKGEVNMQTEEHLNLEKDSEMGIENT 2286
+E + EE +D++I DK E P+ +T E E + E E
Sbjct: 278 EETVTEEITVDEKIYDKLPNEIETVNEEMPVEDETLTEQISSEHERVPEEIIEEKPFTEG 337
Query: 2285 EQKISVXXXXXXXXXXEQKDADVSLEREKIIELNEYKENNRSETSDSGLKETKFESEEEF 2106
E+ S+ + + EK+ E E+ E S+ + K + E+E
Sbjct: 338 EETESLTDEIVEEGVVTDDIPEEQIITEKVQEEEEFV---TGELSEEDIINEKVQEEDE- 393
Query: 2105 DACSKELETTGTCANIETDILEQEEDALKKLDQNLESEKGTMKVEEIQVEVKATDH---- 1938
+ ++EL I + E+EE A +++ Q+ K E + +V+ ++
Sbjct: 394 -SVTEELPEEDI---INEKVQEEEESAYQEIVQDGSVTKDVEYKELVNDDVRDKENFVIE 449
Query: 1937 -----SHKINESHNTAESALLAQDNLEAIDPCDEIKRDTESTDHDQSKEALSEIEKTEVV 1773
INE E + + P E E T+ DQS +E+ V
Sbjct: 450 EDPFKGQLINEGLPVEEEFVTKE------LPVKEESVFEELTEEDQSVTKEIPVEEHSVF 503
Query: 1772 ED-KEIMKYQNVVSVEDHTVGESIQDEENENDSLDEAGPKLNANDQ----NDDMNDVNPP 1608
++ EI + E+ +V E +++E + + +DE ++ N+++
Sbjct: 504 KEVDEIESVTEEIVEEEGSVNEEVEEEVSVSGEVDETEYVTEEVEETELVNEEVLKEEGS 563
Query: 1607 IKDAIVNEEMPHG---VERADNGREETLVGEVGEQCKVDPNFESDLQNEGADKGN-DEED 1440
+ +V EE VE + EET E+ E+ + ES + D+G+ EE
Sbjct: 564 ASEKVVKEEGSASEKIVEEEGSVTEETASEEIVEE-EGSVTEESSSEEIVEDEGSVTEES 622
Query: 1439 KCRKLDAXXXXXXXXXXXXXXVGKQLEEESDLVPGELINEIVTNRTENEGGAPKDTTDT- 1263
++ V ++ ++V E VT E GA D
Sbjct: 623 SSEEIVEEEGSVIEESASEVIVEDEVSASKEIVEDE---ASVTEEVVEEEGAVSDEVQVT 679
Query: 1262 ----DGVIDVNKPAESTFSTNTTSTIEKLHIDEKLLTDNPDASSLTEASQ---------- 1125
D +I+ E + T E + DE ++ + ++TE +
Sbjct: 680 ESVEDEIINQGIVDEVIVEQEASVTDEIVKEDESVIEEIAVEETVTEVVEETKPMDEEIV 739
Query: 1124 ------ESMQEKEGKNTEDGEKQEVV--FVKKATKDMGLPTEES-RENIEHEAPVAEMSK 972
E+++EK+ + E ++ VV +K T D + + S E +E E V E
Sbjct: 740 DQGSVVENVEEKKTMDEEIVDQGSVVENVEEKKTMDEEIGDQGSVAEKVEEEELVTEEVI 799
Query: 971 EGGKKINEVSIEEKSFRNE--------------EGETQVLKQPDTPRDLQMLDQSSDVTA 834
E INE ++E S E E T +K+ P D++ +
Sbjct: 800 EREGSINEDIVKEASITEEVEQIEPVTGKVEKIESITDEIKEQLVPEDIKEEQLDFEEIV 859
Query: 833 EQEASIETDSIEKTKENISIGSIEIPSAPVDVIEKSLQTAE--VEEGKHGEV----QGND 672
Q AS+ + +E + E S +V+E+ T E VEEG EV QG+
Sbjct: 860 AQRASVNDEKVEVASITEEVEE-EEKSVSEEVLEEEGSTTEKVVEEGSSTEVVVEEQGSV 918
Query: 671 SELNTVECEASFDEETNTNSKSSEAKGASLFDLLNKPRKDTG-QAVEQFEEEGNSTSNKE 495
S E +EE +T + E +G+ +LL + G E+F +E +S ++
Sbjct: 919 S-------EEVLEEEGSTTEEVVEEQGSVTENLLEEESASQGIVEKEEFVDEEDSVKDQN 971
Query: 494 QLENKEVLT 468
E + +T
Sbjct: 972 VFEKEGSVT 980
Score = 94.7 bits (234), Expect = 3e-16
Identities = 204/980 (20%), Positives = 408/980 (41%), Gaps = 99/980 (10%)
Frame = -1
Query: 3110 ESDLVSIEEATDSTQETEIVTLEEETPKNSLNDFRA-TEAPLEEITKMKKSDKLNYTPTE 2934
+++ + +E+ +DS EIV E + L + + TE LEE + TE
Sbjct: 3437 DNEEIFVEQISDS----EIVKEENSVNEEVLEEEGSYTEEILEE----------EGSYTE 3482
Query: 2933 SAMSEEQVIKEIPEKTESANHETIFVTQPTEKLSLHEAEPQGGELVDASDDASVEMF--- 2763
+ EE E + E + +E I + + + E E E + + ++ + F
Sbjct: 3483 EILEEEGSFTEEILEEEGSYNEEILEEEGSYNEEILEEEGSFTEEILEEEGSATDYFVGQ 3542
Query: 2762 ----STPIEEHGASSLDPDMEDVKQGEIATLDDNATDNTFTAENAETEHEKPEVPVENSA 2595
IEE A+ + + E+ + T+ F E + TE E+ E E
Sbjct: 3543 GSDNEEIIEEGSATDYFVGQGSIIE-EVLEEEGLDTEKVFENEGSATEFEETESFTE-VV 3600
Query: 2594 VATQSVDKDT-QTTLVSEITASKASSDDLSEE------KPQKSSMLISAKNEFNAVGMKE 2436
T+SV+++ + T ++E+ ++ ++D+ E+ K ++ + + ++ +KE
Sbjct: 3601 EETESVNENILEETSINEVQKIESITEDIKEQLVPEEIKEEQLDSEEIKEEQLDSEEIKE 3660
Query: 2435 K------IKEECQIDDEIKDKKMEAPLVAQTKGEVNMQTEEHLNLEKDSEMGIENTEQKI 2274
+ IKEE + +EIK++++++ + + + EE LN E+ E +++ E I
Sbjct: 3661 EQLDSEEIKEEQLVPEEIKEEQLDSEEIKEEQLVPEEIKEEQLNSEEIKEEQLDSEE--I 3718
Query: 2273 SVXXXXXXXXXXEQKDADVSLER-----EKIIELNEYKENNRSETSDSGLKETKFESEEE 2109
EQ D++ E+ E+++E E + + + E E EE
Sbjct: 3719 KEEQLDSEEIKEEQLDSEEIKEQKGSVNEEVVE-EEGSVTEEIKEQEESVNEEVLEEVEE 3777
Query: 2108 FDACSKELETTGTCANIETDILEQEEDALKKLDQN-LESEK----GTMKVEEIQVEVKAT 1944
++ +E+ G +I+E+E D + +++ ++SEK G++ E + EV T
Sbjct: 3778 TESIKEEIVEGGIATQ---EIIEEESDTKEVVEEEVIDSEKLVDAGSVTGEVMPEEVSVT 3834
Query: 1943 DHSHKINESHNTAESALLAQD--NLEAID---PCDEIKRDTESTDHDQSKEALSEIEK-- 1785
D ++ E +T E L Q N E ++ D+ ST + +E S IEK
Sbjct: 3835 D---EVVEEGSTTEEVLEEQKSVNEEVVEDGLTIDDFVGLQGSTTEEVVEEDGSAIEKIL 3891
Query: 1784 -----TEVVEDKEIMKYQNVVS---------VEDHTVGESI------------QDEENEN 1683
TE + +K++ +++V +E+ +V E I Q+E
Sbjct: 3892 EEETATEEIVEKQVSVTEDIVEKEGSVNEEIIEEASVAEEIIQGGSFTEEIVGQEESATE 3951
Query: 1682 DSLDEAGPKLNANDQNDDMN---DVNPPIKDAIVNEEMPHGVERADNGREETLVGE--VG 1518
+ +DE G N ++ ++ + ++ +++ V++E+ V A+ EE LV + +
Sbjct: 3952 EVIDEEGLISNEIEEEEEKSVTEEMIEEVEEVSVDDEVEE-VSVAEEIVEEELVDDEILP 4010
Query: 1517 EQCKVDPNFESDLQNEGADKGNDEEDKC-----RKLDAXXXXXXXXXXXXXXVGKQLEEE 1353
E+ + ++++ D+ EE C +++ A VG +
Sbjct: 4011 EELSATEDVIEEVRSV-TDEIVQEESVCEEILEQEVSASEEYVDDKSVTDDFVGHERSVI 4069
Query: 1352 SDLVPGELINE--------IVTNRTENEGGAPKDTT-----DTDGVIDVNKPAESTFSTN 1212
D+ E + E ++ E +G ++ DT+ V++ +K
Sbjct: 4070 QDVENTESVTEEIAEVDKSVIEEAVEKQGSVTEEIVEEEELDTEEVLE-DKSVTGDVVEQ 4128
Query: 1211 TTSTIEKLHIDEKLLTDNPDASSLTEASQE----SMQEKEGKNTEDGEKQEVVFVKKATK 1044
S ++ E + + S+ E QE S + +E TE +QE+ K+ +
Sbjct: 4129 EGSGKDESEAKESFTEEVDELKSVKEEDQETEYISREIEEESATEQHSEQELSINKEVVE 4188
Query: 1043 DMGLPTEESRENIEHEAPVAEMSKEGGKKINEVSIEEKSFRNEEGETQVLKQPDTPRDLQ 864
TE ++IE E + E + +NE +EE E +VLK+ +P +
Sbjct: 4189 -----TESLTKDIEEEKSTTQEILEETQSVNEEIVEE-----ERDTDEVLKEKVSPSEEV 4238
Query: 863 MLDQSSDVTAEQEASIETDSIEKTKENISIGSIEIP-SAPVDVIEKSLQTAEV--EEGKH 693
+ +Q+S E TD I + ++ + E S +++E+ T E+ EEG
Sbjct: 4239 IEEQASTTEEFLEERSSTDEIVEVEDLFTEEVKEREGSVTEEIVEEGSDTGEIVEEEGSD 4298
Query: 692 GEVQGNDSELN--TVECEASFDEETNTNSKSSE---AKGASLFDLLNKPRKDTGQAVEQF 528
E + N VE E S EE S + E +G+ + +++ +T A+E+
Sbjct: 4299 AEEILEEGSFNEEIVEEEGSITEEILQGSVTEEFVGQQGSVIEEIV-----ETESAIEER 4353
Query: 527 EEEGNSTSNKEQLENKEVLT 468
E+ ++T E+++ +E +T
Sbjct: 4354 VEDESAT---EEVDERESVT 4370
Score = 89.7 bits (221), Expect = 9e-15
Identities = 201/989 (20%), Positives = 381/989 (38%), Gaps = 116/989 (11%)
Frame = -1
Query: 3092 IEEATDSTQ-ETEIVTLEEETPKNSLNDFRATEAPL-EEITKMKKSDKLNYTPTES--AM 2925
I+E + + +T+ V E E + + + E + EEI + +K +N E ++
Sbjct: 2938 IDEIVEEDELDTKEVVEEIEFNTEEVVEHKEEEGSVAEEIVQEEKEGSVNEEIIEEVGSI 2997
Query: 2924 SEEQVIKEIPEKTESANHETIFVTQPTEKLSLHEAEPQG---GELVDASDDASVEMFSTP 2754
+EE V +++ + E ++ E E +G E++D D S +
Sbjct: 2998 TEEMVEQDVSDNEEIVEERSVIEEAEENVWIEKEVEEEGLDNEEVIDEEDSVSEQAEEEV 3057
Query: 2753 IEEHGASSLDPDMEDVKQGEIATLDDNATDNTFTAENAETEHEKPEVPVENSAVATQSV- 2577
D+EDVK ++ + AEN E + E VE + T+ V
Sbjct: 3058 YINEEILKESSDVEDVKVENELMNEEVNEETQSVAENNEEDKELDNYVVEETESVTEEVV 3117
Query: 2576 ------DKDTQ--TTLVSEITASKASSDDL-----------SEEKPQKSSMLISAKNEFN 2454
K+ Q +++ EI ++DDL EE S ++ +
Sbjct: 3118 VDEVPNSKEVQEIESIIEEIVEDGLTTDDLVGQQGSVIEEVVEEVGSDSEGIVEEASITE 3177
Query: 2453 AVGMKEKIKEECQIDDEIK-DKKMEAPLVAQTKGEVNMQTEEHLNLEKD--SEMGIENTE 2283
V KE + E+ +++ + D +E + + GE + +EE + E E+ E+
Sbjct: 3178 EVEKKESVTEDILVEESVTGDILVEGSVTEEVVGEEKLVSEEIVTEEGSVAQEIVEEDAP 3237
Query: 2282 QKISVXXXXXXXXXXEQKDADVSLE--------REKIIE----LNEYKENNRSETSDSGL 2139
+ +++ V E E+II+ + E E SE + +
Sbjct: 3238 ATEEIDEIESVTEEVVEEEGPVDEEIVQEEGSVTEEIIQGESKVEEVVEEQGSENEEIFV 3297
Query: 2138 KETKFESE--EEFDACSKELETTGTCANIETD--ILEQEEDALKKLDQNLESEKGTMKVE 1971
+E E + + LE I D + EQ + K + + + +E+ ++ E
Sbjct: 3298 EEVSASQEIVQNESGTEEILEKVSASQEIVQDGSVTEQIIEEQKPVTEEVVNEEESITHE 3357
Query: 1970 EIQVEVKATDHSHKINESHNTAESALLAQDNLEAIDPCDEIKRDTESTDHDQSKEALSEI 1791
IQ E H K+ + + AE + +N ++ K + + D Q EI
Sbjct: 3358 IIQEE----SHVEKVVQQGSVAEEVV---ENPVSVTEEIVEKEGSVTEDIGQEGYVAEEI 3410
Query: 1790 EKTEVVEDKEIMKYQNVVSVEDHTVGESIQDEENENDSLDEAGPKLNANDQNDDMNDVNP 1611
+ E +++EI++ + SV + V E +EE + + ++ N N+++ +
Sbjct: 3411 VEEEEFDNEEILEEE---SVAEEFVEEGFDNEEIFVEQISDSEIVKEENSVNEEVLEEEG 3467
Query: 1610 PIKDAIVNEEMPHGVE--RADNGREETLVGEVGEQCKVDPNFESDLQNEGADKGNDEEDK 1437
+ I+ EE + E + E ++ E G E L+ EG+ E++
Sbjct: 3468 SYTEEILEEEGSYTEEILEEEGSFTEEILEEEGSY------NEEILEEEGSYNEEILEEE 3521
Query: 1436 CRKLDAXXXXXXXXXXXXXXVGKQLEE--------ESDLVPGELINEIVTNR-------T 1302
+ G EE + + G +I E++
Sbjct: 3522 GSFTEEILEEEGSATDYFVGQGSDNEEIIEEGSATDYFVGQGSIIEEVLEEEGLDTEKVF 3581
Query: 1301 ENEGGAPKDTTDTDGVIDVNKPAEST-------FSTNTTSTIEKLHID-------EKLLT 1164
ENEG A + +T+ +V + ES S N IE + D E++
Sbjct: 3582 ENEGSA-TEFEETESFTEVVEETESVNENILEETSINEVQKIESITEDIKEQLVPEEIKE 3640
Query: 1163 DNPDASSLTEASQESMQEKEGKNTEDGEKQEVVFVKKATKDMGLPTEESR------ENIE 1002
+ D+ + E +S + KE + + E +E V + K+ L +EE + E I+
Sbjct: 3641 EQLDSEEIKEEQLDSEEIKE-EQLDSEEIKEEQLVPEEIKEEQLDSEEIKEEQLVPEEIK 3699
Query: 1001 HEAPVAEMSKE---GGKKINEVSIEEKSFRNEEGETQVLKQPDTPRDLQMLDQSSDVT-- 837
E +E KE ++I E ++ + + E+ +++ +K+ + +++++ VT
Sbjct: 3700 EEQLNSEEIKEEQLDSEEIKEEQLDSEEIKEEQLDSEEIKEQKGSVNEEVVEEEGSVTEE 3759
Query: 836 -AEQEASIETDSIEKTKENISIGS--IEIPSAPVDVIEKSLQTAEVEEGK---------- 696
EQE S+ + +E+ +E SI +E A ++IE+ T EV E +
Sbjct: 3760 IKEQEESVNEEVLEEVEETESIKEEIVEGGIATQEIIEEESDTKEVVEEEVIDSEKLVDA 3819
Query: 695 ---HGEVQGND-SELNTVECEASFDEETNTNSKSSEAK----GASLFDLLNKPRKDT--- 549
GEV + S + V E S EE KS + G ++ D + T
Sbjct: 3820 GSVTGEVMPEEVSVTDEVVEEGSTTEEVLEEQKSVNEEVVEDGLTIDDFVGLQGSTTEEV 3879
Query: 548 ----GQAVEQFEEEGNSTSNKEQLENKEV 474
G A+E+ EE +T E++ K+V
Sbjct: 3880 VEEDGSAIEKILEEETAT---EEIVEKQV 3905
Score = 85.5 bits (210), Expect = 2e-13
Identities = 186/914 (20%), Positives = 344/914 (37%), Gaps = 42/914 (4%)
Frame = -1
Query: 3116 VKESDLVSIEEATDSTQETEIVTLEEETPKNSL-NDFRATEAPLEEITKMKKSDKLNYTP 2940
++E + VS+++ + E + EE L + ATE +EE+ +
Sbjct: 3977 IEEVEEVSVDDEVEEVSVAEEIVEEELVDDEILPEELSATEDVIEEVRSV---------- 4026
Query: 2939 TESAMSEEQVIKEIPEKTESANHETIFVTQPTEKLSLHEAEP-QGGELVDASDDASVEMF 2763
T+ + EE V +EI E+ SA+ E + T+ HE Q E ++ + E+
Sbjct: 4027 TDEIVQEESVCEEILEQEVSASEEYVDDKSVTDDFVGHERSVIQDVENTESVTEEIAEVD 4086
Query: 2762 STPIEEHGASSLDPDMEDVKQGEIAT--------------------LDDNATDNTFTAE- 2646
+ IEE E V++ E+ T D++ +FT E
Sbjct: 4087 KSVIEEAVEKQGSVTEEIVEEEELDTEEVLEDKSVTGDVVEQEGSGKDESEAKESFTEEV 4146
Query: 2645 ---------NAETEHEKPEVPVENSAVATQSVDKDTQTTLVSEITASKASSDDLSEEKPQ 2493
+ ETE+ E+ E SA S + + ++ E+ +++ + D+ EEK
Sbjct: 4147 DELKSVKEEDQETEYISREIE-EESATEQHS---EQELSINKEVVETESLTKDIEEEKST 4202
Query: 2492 KSSMLISAKNEFNAVGMKEKIKEECQIDDEIKDKKMEAPLVAQTKGEVNMQTEEHLNLEK 2313
+L E +V +E ++EE D+ +K+K + V + + TEE L E+
Sbjct: 4203 TQEIL----EETQSVN-EEIVEEERDTDEVLKEKVSPSEEVIEEQAST---TEEFLE-ER 4253
Query: 2312 DSEMGIENTEQKISVXXXXXXXXXXEQKDADVSLEREKIIELNEYKENNRSETSDSG--L 2139
S I E + K+ + S+ E + E ++ E E SD+ L
Sbjct: 4254 SSTDEIVEVEDLFTEEV----------KEREGSVTEEIVEEGSDTGEIVEEEGSDAEEIL 4303
Query: 2138 KETKFESE--EEFDACSKEL---ETTGTCANIETDILEQEEDALKKLDQNLESEKGTMKV 1974
+E F E EE + ++E+ T + ++E+ + +++ +E E T +V
Sbjct: 4304 EEGSFNEEIVEEEGSITEEILQGSVTEEFVGQQGSVIEEIVETESAIEERVEDESATEEV 4363
Query: 1973 EEIQVEVKATDHSHKINESHNTAESALLAQDNLEAIDPCDEIKRDTESTDHDQSKEALSE 1794
+E + + + +++ S E ++ E +EI S D + +A+S
Sbjct: 4364 DERESVTEVVEE--EVSSSDEVVEGSIEEVIENEG-SVTEEILEHEVSADENFVGQAVSV 4420
Query: 1793 IEKTEVVEDKEIMKYQNVVSVEDHTVGESIQDEENENDSLDEAGPKLNANDQNDDMNDVN 1614
IE+ E E E +++ E+ ++ + E P N Q D + + +
Sbjct: 4421 IEEVEGTES---------------VTEEVVEETESVSEEIVEVSPTENVVQQTDSVIEED 4465
Query: 1613 PPIKDAIVNEEMPHGVERADNGREETLVGEVGEQCKVDPNFESDLQNEGADKGNDEEDKC 1434
K+ NEE+ E D+G EE E D + D++ E + G+ EE
Sbjct: 4466 VEQKEGSFNEEIDIR-ELGDDGVEEREKISTEEVVGQDKSATGDVE-ESSSTGDVEEVS- 4522
Query: 1433 RKLDAXXXXXXXXXXXXXXVGKQLEEESDLVPGELINEIVTNRTENEGGAPKDTTDTDGV 1254
E+E ++ E + E+ + E +D +
Sbjct: 4523 ----------------------STEDEEEVSSTEGLEEVSSTEGLEEVSNTEDVEEVSST 4560
Query: 1253 IDVNKPAESTFSTNTTSTIEKLHIDEKLLTDNPDASSLTEASQESMQEKEGKNTEDGEKQ 1074
DV + + + T S E++ ++E ++TD QE M E +
Sbjct: 4561 EDVEEGSVAENVKETKSITEEVSVEEDIITDK------VSVEQEVMAEASVE-------- 4606
Query: 1073 EVVFVKKATKDMGLPTEESRENIEHEAPVAEMSKEGGKKINEVSIEEKSFRNEEGETQVL 894
ENI E PV E + + ++ EK EE ++
Sbjct: 4607 --------------------ENILTEVPVEEEIMTEKLSVEDKALNEKIMSEEE----IV 4642
Query: 893 KQPDTPRDLQMLDQSSDVTAEQEASIETDSIEKTKENISIGSIEIPSAPVDVIEKSLQTA 714
+ ++ V AE + E +E+T N S E V V + S+
Sbjct: 4643 IEDGNVHEV--------VPAEVSVTEEIPGVEETTNNESHVKGENVVNEVVVDDNSV--- 4691
Query: 713 EVEEGKHGEVQGNDS---ELNTVECEASFDEETNTNSKSSEAKGASLFDLLNKPRKDTGQ 543
+ E+Q +D E+ TV+ + F +E N +S E + + ++ RK
Sbjct: 4692 ------NDEIQFDDDSSIEIYTVDSKDVFHKEENYDSFREEVRSD---ENIHISRKKNEN 4742
Query: 542 AVEQFEEEGNSTSN 501
V++ E E +S +
Sbjct: 4743 FVKKIENEKSSVGH 4756
Score = 72.4 bits (176), Expect = 2e-09
Identities = 185/902 (20%), Positives = 361/902 (40%), Gaps = 42/902 (4%)
Frame = -1
Query: 3092 IEEATDSTQETEIVTLEEETPKNSLNDFRATEAPL------EEITKMKKSDKLNYTPTES 2931
IEE ++ TE V E +++ + E P+ EE++ +K D+++ + TE
Sbjct: 1490 IEEIVETESSTEKVL---EDVGSNVEEIVQEEGPVAQEIVHEEVSTTEKHDEVDRSTTEE 1546
Query: 2930 ------AMSEEQVIKEIPEKTESANHETIFVTQPTEKLSLHEAEPQGGELVDASDDASVE 2769
++SEE +++E+ E ++ E+ ++E GE +++ +
Sbjct: 1547 IVEKVGSVSEEIIVEEVSASEEIVEEGSVTEEVVEEEKLINEV----GETESVTEEIVQK 1602
Query: 2768 MFSTPIEEHGAS-SLDPDMEDVKQ------GEIATLDDNATDNTFTAENAETEHEKPEVP 2610
S E G S++ ++ + + G ++ + D AE + E E
Sbjct: 1603 EVSDAEEVLGQEGSMNEEILEKESIVEEIVGPEGSVTEEIVDYGSFAEEVKEEELVTEEA 1662
Query: 2609 VENSAVATQSVDKDTQTTLVSEITASKASSDDLSEEKPQKSSMLISAKNEFNAVGMKEKI 2430
V+ T+ + K+ ++ +E A ++ + E+ P ++ K E + +E +
Sbjct: 1663 VQYEGSVTEEI-KEEESITENEAIEESAFAEIIEEKGPNNDEIV---KEE--GLDTEEIV 1716
Query: 2429 KEECQIDDEIKDKKMEAPLVAQTKGEVNMQTEEHLNLEKDS-----EMGIENTEQKISVX 2265
E D+ I+++K+ + Q GE TE+ + +E+ + E G TE K+SV
Sbjct: 1717 NEVSVTDEVIEEEKL---VNEQIVGEERSVTEKPVEVERSATEDLVEEGASVTE-KVSVH 1772
Query: 2264 XXXXXXXXXEQKDADVSLERE-----KIIELNEYKENNRSETSDSGLKETKFESEEEFDA 2100
++ A+ +E E KIIE E + E S ++E E EE
Sbjct: 1773 EGSTTEQILDESVAEEIVEEEVSVDDKIIE-EEVSVDEVVEEEGSVIEEI-VEEEESVPE 1830
Query: 2099 CSKELETTGTCANIETD-----ILEQEEDALKKLDQNLESEKGTMKVEEIQVEVKATDHS 1935
E E +G+ +E + + QE ++++++ ++ E EEI + A +
Sbjct: 1831 EILEEELSGSEEVLEDEWVTDAFMGQEGSVIEEIEEIVDGEGSI--TEEIVEDGSANE-- 1886
Query: 1934 HKINESHNTAESALLAQDNL---EAIDPCDEIKRDTESTDHDQSKEALSEIEKTEVVEDK 1764
KI E + +L ++ E I+ I++ ++ + E S IE+ + V+++
Sbjct: 1887 -KIVEEEPSRVEEVLGKEGFVIEEIIEEGSVIEQVEDTKTVSEKSEESSAIEEVKEVKEE 1945
Query: 1763 EIMKYQNVVSVEDHTVGESIQDEENENDSLDEAGPKLNANDQNDDMNDVNPPIKDAIVNE 1584
E + + +V E+ E ++ EE+ + + +KD E
Sbjct: 1946 ESIS-EKIVEKEESVTEEIVRQEESTTEKI----------------------VKDVSPTE 1982
Query: 1583 EMPHGVERADNGREETLVGEVGEQCKVDPNFESDLQNEGADKGNDEEDKCRKLDAXXXXX 1404
+ VE+ D+ E+ + E G +V + E + E A +++ED
Sbjct: 1983 DF---VEQTDSVTEKVIEQE-GSNTEVAEDVE---EKESASDEHEQED------------ 2023
Query: 1403 XXXXXXXXXVGKQLEEESDLVPGELINEIVTNRTEN---EGGAPKDTTDTDGVIDVNKPA 1233
V Q+ E V E+++E+ +RTE E G+ + D G +
Sbjct: 2024 -------VSVNAQVTCEKKSVTKEIVDEV--SRTEEIVEENGSVTEGVDETGSV------ 2068
Query: 1232 ESTFSTNTTSTIEKLHIDEKLLTDNPDASSLTEASQESMQEKEGKNTEDGEK-QEVVFVK 1056
T IE+ + E+++ D S+TE + EDG QEVV
Sbjct: 2069 -------TEEIIEEATVTEEVVEDG----SVTE-----------EVVEDGSVIQEVV--- 2103
Query: 1055 KATKDMGLPTEESRENIEHEAPVAEMSKEGGKKINEVSIEEKSFRNEEGETQVLKQPDTP 876
+ G TEE ++ V E E +NE EE S E ET+ + +
Sbjct: 2104 ----EDGSVTEEI---VQENGSVTEEIVEEEGSVNEEVEEEVSVSGEVDETEYVTE---- 2152
Query: 875 RDLQMLDQSSDVTAEQEASIETDSIEKTKENISIGSIEIPSAPVDVIEKSLQTAEVEEGK 696
+++ + E+E S+ + +E+ + E S +++E+ E +
Sbjct: 2153 -EVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEE 2211
Query: 695 HGEVQGNDSELNTVECEASFDEETNTNSKSSEAKGASLFDLLNKPRKDTGQAVEQF-EEE 519
G V E E +EE + + E +G+ + +++ ++ G VE+ EEE
Sbjct: 2212 EGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIV----EEEGSVVEEIVEEE 2267
Query: 518 GN 513
G+
Sbjct: 2268 GS 2269
Score = 69.3 bits (168), Expect = 1e-08
Identities = 184/908 (20%), Positives = 352/908 (38%), Gaps = 34/908 (3%)
Frame = -1
Query: 3095 SIEEATDSTQ--ETEIVT----LEEETPKNSLNDFRATEAPLEEITKMKKSDKLNYTPTE 2934
S+ E D T+ EIV EE + S+ND +A + E +++S+ + + ++
Sbjct: 2335 SVSEVVDETELVNDEIVEQAPFTEEVEEQVSVNDEIIEDASVAEA--VEESESITESVSQ 2392
Query: 2933 SAMSEEQVIKEIPEKTESANHETIFVTQPTEKLSLHEAEPQGGELVDASDDASVEMFSTP 2754
+E+ + E E+T + E + TE++ L E+E GE+++ DA + +
Sbjct: 2393 EEETEKGFVIEKVEETGAVTEEIVQDGLITEEI-LEESESVNGEIINKESDAEEILETEF 2451
Query: 2753 IEEHGASSLDPDMEDVKQGEIATLDDNATDNTFTAENAETEHEKPEVPVENSAVATQSVD 2574
+ E E++ + E + T E E E E+ V+ +V + VD
Sbjct: 2452 LTEEVVGQAGSTSEEIVEEE----------GSVTKEVEEKESVTEEL-VDEGSVTEELVD 2500
Query: 2573 KDTQTTLVSEITASKASSDDLSEEKPQKSSMLISAKNEFNAVGMKEKIKEECQIDDEIKD 2394
+ + T V E S A ++ EE+ ++ N ++E +++E +EI
Sbjct: 2501 EGSVTEEVVEQGGSIAQ--EIVEEESATEEIIRDETN------VEEVLEKEGSATEEI-- 2550
Query: 2393 KKMEAPLVAQTKGEVNMQTEEHLNLEKDSEMGIENTEQKISVXXXXXXXXXXEQKDADVS 2214
V G + ++ +E+ E I TE+K+
Sbjct: 2551 -------VQDGSGTNDFVGKQGSVIEEVVEEEISTTEEKLK------------------- 2584
Query: 2213 LEREKIIELNEYKENNRSETSDSGLKETKFESEEEFDACSKELETTGTCANIETDILEQE 2034
E IE +E+ R + + L ++E S E + DI+E+E
Sbjct: 2585 -EEASAIEEFVEEESIREDVLEESLVTENVVGQQE----SVTEEIVDGEGSFTEDIVEEE 2639
Query: 2033 EDALKKLDQNLES-EKGTMKVEEIQVEVKATDHSHKINESHNTAESALLAQDNLEAIDPC 1857
E +++ + ES K ++ EE+ E D
Sbjct: 2640 ESVTEEIVVDEESVTKEIVEDEELVTEEIVEDEGSFT----------------------- 2676
Query: 1856 DEIKRDTESTDHD--QSKEALSEIEKTEVVEDKE---IMK-------YQNVVSVEDHTVG 1713
+EI D S + + + + E+E TE V +KE ++K + E+ +V
Sbjct: 2677 EEIVEDEGSFTEEVIEERSLIEEVEDTETVAEKEEGSVIKEIIDEKSLTEKIVEEEKSVT 2736
Query: 1712 ESIQDEENENDSLDEAGPKLNANDQNDDMNDVNPPIKDAIVNEEMPHGVERADNGREETL 1533
E ++++E+ + ++E +L ++ + ++D + E + + + E+ L
Sbjct: 2737 EEVEEKESVKEEVEE--QRLVVEEEGSATEGI---VEDRLATEGIVDDILVTEEIVEDGL 2791
Query: 1532 VGE--VGEQCKVDPNFESDLQNEGA-------DKGNDEEDKCRKLDAXXXXXXXXXXXXX 1380
+ V +Q + E L +EG+ ++G+ E+ +
Sbjct: 2792 ATDEFVEQQGSI---IEEVLDDEGSVTEEIVEEEGSPNEEIVEGVSV------------- 2835
Query: 1379 XVGKQLEEESDLVP--GELINEIVTNRTENEGGAPKDTTDTDGVIDVNKPAESTFSTNTT 1206
+EE+ ++ P E++ VT EG + D D + + E + S
Sbjct: 2836 -----IEEDDNIEPVSEEIVEGSVTEEMIKEGLENEVILDEDSITEEALEKEGSVSEEIV 2890
Query: 1205 STIEKLH---IDEKLLTDNPDASSLTEASQESMQEKEGKNTEDGEKQEVVFVKKATKDMG 1035
+ L +DE+ T + D AS+E +QE ++ + +EV + + ++
Sbjct: 2891 EEMGSLTEEIVDEERST-SEDMIEEGSASEEIIQE---ESQVEEVVEEVSVIDEIVEEDE 2946
Query: 1034 LPTEESRENIE-HEAPVAEMSKEGGKKINEVSIEEKSFRNEEGETQVLKQPDTPRDLQML 858
L T+E E IE + V E +E G E+ EEK E +++++ + + +M+
Sbjct: 2947 LDTKEVVEEIEFNTEEVVEHKEEEGSVAEEIVQEEKEGSVNE---EIIEEVGSITE-EMV 3002
Query: 857 DQSSDVTAEQEASIETDSIEKTKENISIGSIEIPSAPVDVIEKSLQTAEVEEGKHGEVQG 678
+Q DV+ +E E IE+ +EN+ I +V E+ L EV +
Sbjct: 3003 EQ--DVSDNEEIVEERSVIEEAEENVWIEK--------EVEEEGLDNEEV-------IDE 3045
Query: 677 NDSELNTVECEASFDEETNTNSKSSEAKGASLFDLLNKPRKDTGQAVEQFEEEGNSTSNK 498
DS E E +EE S E +L+N+ + Q+V + EE N
Sbjct: 3046 EDSVSEQAEEEVYINEEILKESSDVEDVKVE-NELMNEEVNEETQSVAENNEEDKELDNY 3104
Query: 497 EQLENKEV 474
E + V
Sbjct: 3105 VVEETESV 3112