BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Chrysanthemum22_contig00035941
         (975 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_022015799.1| tyrosyl-DNA phosphodiesterase 1 isoform X1 [...   479   e-163
ref|XP_023743532.1| tyrosyl-DNA phosphodiesterase 1 [Lactuca sat...   458   e-155
ref|XP_019078223.1| PREDICTED: tyrosyl-DNA phosphodiesterase 1 i...   409   e-137
dbj|GAV73664.1| Tyr-DNA_phospho domain-containing protein [Cepha...   408   e-135
ref|XP_010655352.1| PREDICTED: tyrosyl-DNA phosphodiesterase 1 i...   409   e-135
ref|XP_016432676.1| PREDICTED: tyrosyl-DNA phosphodiesterase 1-l...   393   e-135
ref|XP_017231366.1| PREDICTED: tyrosyl-DNA phosphodiesterase 1 i...   403   e-134
ref|XP_017231364.1| PREDICTED: tyrosyl-DNA phosphodiesterase 1 i...   403   e-133
gb|PIN03584.1| Phosphodiesterase I [Handroanthus impetiginosus]       392   e-133
ref|XP_015067766.1| PREDICTED: tyrosyl-DNA phosphodiesterase 1 [...   401   e-133
ref|XP_010240926.1| PREDICTED: tyrosyl-DNA phosphodiesterase 1 i...   399   e-132
ref|XP_006343414.2| PREDICTED: tyrosyl-DNA phosphodiesterase 1 [...   398   e-131
gb|OMO76723.1| hypothetical protein CCACVL1_15470 [Corchorus cap...   404   e-131
gb|PKI40197.1| hypothetical protein CRG98_039390 [Punica granatum]    390   e-131
ref|XP_022870063.1| tyrosyl-DNA phosphodiesterase 1-like [Olea e...   391   e-131
ref|XP_010317667.1| PREDICTED: tyrosyl-DNA phosphodiesterase 1 [...   397   e-131
ref|XP_023920145.1| tyrosyl-DNA phosphodiesterase 1 [Quercus suber]   397   e-131
gb|POF00599.1| tyrosyl-dna phosphodiesterase 1 [Quercus suber]        397   e-130
ref|XP_020217732.1| tyrosyl-DNA phosphodiesterase 1 isoform X2 [...   394   e-130
gb|KYP67403.1| Tyrosyl-DNA phosphodiesterase 1 [Cajanus cajan]        394   e-130

>ref|XP_022015799.1| tyrosyl-DNA phosphodiesterase 1 isoform X1 [Helianthus annuus]
 gb|OTF90890.1| putative tyrosyl-DNA phosphodiesterase [Helianthus annuus]
          Length = 648

 Score =  479 bits (1232), Expect = e-163
 Identities = 228/255 (89%), Positives = 241/255 (94%), Gaps = 1/255 (0%)
 Frame = +3

Query: 3    MKLRSILKECVFDKEFQNSPLIYQFSSLGSLDEKWMTEFAFSMSSGVSDDKKPLGLGEPL 182
            MK+RS+L++CVFDKEF+N+PLIYQFSSLGSLDEKWM EFAFSMSSGVSDDKKPLGLGEPL
Sbjct: 394  MKIRSVLQDCVFDKEFRNAPLIYQFSSLGSLDEKWMAEFAFSMSSGVSDDKKPLGLGEPL 453

Query: 183  IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWAKWKASHSGRCRAMPHIKTFTR 362
            IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYW KWKA+H+GRCRAMPHIKTFTR
Sbjct: 454  IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWGKWKATHTGRCRAMPHIKTFTR 513

Query: 363  YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSSATQAHAFSCTENGS 542
            YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSS + AH FSCTENGS
Sbjct: 514  YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSSTSHAHVFSCTENGS 573

Query: 543  TSENK-CGPSLKTPEAKRTKLVSLASIHSKRMDLPDVITLPVPYELPPQRYSSEDVPWSW 719
            TSENK  G  LKT EAKRTKLV+LAS HSK+M LPDV+TLPVPYELPP RYSSEDVPWSW
Sbjct: 574  TSENKYSGSPLKTHEAKRTKLVTLASPHSKKMHLPDVVTLPVPYELPPARYSSEDVPWSW 633

Query: 720  DRQYKKRDVFGQVWP 764
            D+QYKKRDV GQVWP
Sbjct: 634  DKQYKKRDVLGQVWP 648


>ref|XP_023743532.1| tyrosyl-DNA phosphodiesterase 1 [Lactuca sativa]
          Length = 650

 Score =  458 bits (1179), Expect = e-155
 Identities = 223/255 (87%), Positives = 237/255 (92%), Gaps = 1/255 (0%)
 Frame = +3

Query: 3    MKLRSILKECVFDKEFQNSPLIYQFSSLGSLDEKWMTEFAFSMSSGVSDD-KKPLGLGEP 179
            MKLRSIL++CVFDKEFQNSPLIYQFSSLGSLDEKWM+EFAFSMSSGVSDD KKPLGLG+P
Sbjct: 398  MKLRSILQDCVFDKEFQNSPLIYQFSSLGSLDEKWMSEFAFSMSSGVSDDNKKPLGLGDP 457

Query: 180  LIVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWAKWKASHSGRCRAMPHIKTFT 359
            LIVWPTVEDIRCSLEGYAAGSCVPSPQKNVEK FLKKYWAKWKA+H+GRCRA+PHIKTFT
Sbjct: 458  LIVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKPFLKKYWAKWKATHTGRCRAIPHIKTFT 517

Query: 360  RYNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSSATQAHAFSCTENG 539
            RYNGQNLAWFLLTS+NLSKAAWGALQKNNTQLMIRSYELGVLFLPSS   AHAFSCTEN 
Sbjct: 518  RYNGQNLAWFLLTSANLSKAAWGALQKNNTQLMIRSYELGVLFLPSSTIHAHAFSCTENR 577

Query: 540  STSENKCGPSLKTPEAKRTKLVSLASIHSKRMDLPDVITLPVPYELPPQRYSSEDVPWSW 719
            + SEN    S KT E KRTKLV+L+S+H+ +M   DVITLPVPYELPPQRYSSEDVPWSW
Sbjct: 578  TPSENIHVSSSKTHEEKRTKLVTLSSLHTNKMS--DVITLPVPYELPPQRYSSEDVPWSW 635

Query: 720  DRQYKKRDVFGQVWP 764
            DRQYKKRDVFGQVWP
Sbjct: 636  DRQYKKRDVFGQVWP 650


>ref|XP_019078223.1| PREDICTED: tyrosyl-DNA phosphodiesterase 1 isoform X2 [Vitis
            vinifera]
          Length = 557

 Score =  409 bits (1050), Expect = e-137
 Identities = 195/255 (76%), Positives = 222/255 (87%), Gaps = 1/255 (0%)
 Frame = +3

Query: 3    MKLRSILKECVFDKEFQNSPLIYQFSSLGSLDEKWMTEFAFSMSSGVSDDKKPLGLGEPL 182
            MKL S+L+EC+FDKEFQ SPL YQFSSLGSLDEKWMTE A SMSSG  DDK PLGLG+PL
Sbjct: 293  MKLCSVLQECIFDKEFQKSPLAYQFSSLGSLDEKWMTELASSMSSGSCDDKTPLGLGKPL 352

Query: 183  IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWAKWKASHSGRCRAMPHIKTFTR 362
            I+WPTVED+RCSLEGYAAG+ +PSPQKNVEK FLKKYWAKWKA+H+GRCRAMPHIKT+TR
Sbjct: 353  IIWPTVEDVRCSLEGYAAGNAIPSPQKNVEKEFLKKYWAKWKATHTGRCRAMPHIKTYTR 412

Query: 363  YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSSATQAHAFSCTENGS 542
            YNGQNLAWFLLTS+NLSKAAWGALQKNN+QLMIRSYELGVLFLPS   +   FSCT+NGS
Sbjct: 413  YNGQNLAWFLLTSANLSKAAWGALQKNNSQLMIRSYELGVLFLPSPINRGQGFSCTDNGS 472

Query: 543  TSENKCGPSLKTPEAKRTKLVSLASIHSKRMD-LPDVITLPVPYELPPQRYSSEDVPWSW 719
             S+NKCG S  T +++RTKLV+L    ++  D   +VI LPVPYELPP++YSSEDVPWSW
Sbjct: 473  PSKNKCGLSENT-KSQRTKLVTLTWEGNRSSDSSSEVIPLPVPYELPPKQYSSEDVPWSW 531

Query: 720  DRQYKKRDVFGQVWP 764
            DR+Y K+DV GQVWP
Sbjct: 532  DRRYYKKDVCGQVWP 546


>dbj|GAV73664.1| Tyr-DNA_phospho domain-containing protein [Cephalotus follicularis]
          Length = 660

 Score =  408 bits (1049), Expect = e-135
 Identities = 196/259 (75%), Positives = 222/259 (85%), Gaps = 1/259 (0%)
 Frame = +3

Query: 3    MKLRSILKECVFDKEFQNSPLIYQFSSLGSLDEKWMTEFAFSMSSGVSDDKKPLGLGEPL 182
            MKLR+IL+EC FDKEFQNSPL+YQFSSLGSLDEKWMTE A SMSSG S+DK PLGLGEPL
Sbjct: 396  MKLRTILQECTFDKEFQNSPLVYQFSSLGSLDEKWMTELASSMSSGFSEDKMPLGLGEPL 455

Query: 183  IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWAKWKASHSGRCRAMPHIKTFTR 362
            I+WPTVED+RCSLEGYAAGS +PSPQKNVE+ FLKKYWAKWKA H+GRCRAMPHIKT+TR
Sbjct: 456  IIWPTVEDVRCSLEGYAAGSAIPSPQKNVEREFLKKYWAKWKAIHTGRCRAMPHIKTYTR 515

Query: 363  YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLP-SSATQAHAFSCTENG 539
            YNGQ LAWFLLTS+NLSKAAWGALQKNN+QLMIRSYELGVLFLP  +    + FSCT+NG
Sbjct: 516  YNGQKLAWFLLTSANLSKAAWGALQKNNSQLMIRSYELGVLFLPYPTRRHGYGFSCTDNG 575

Query: 540  STSENKCGPSLKTPEAKRTKLVSLASIHSKRMDLPDVITLPVPYELPPQRYSSEDVPWSW 719
              S +K   S +  +A   KLV+L S  S+  DL DVI LPVPYELPPQ+YSSEDVPWSW
Sbjct: 576  GPSLDKF-ESTENSKAAMGKLVTLTSQGSRNTDLSDVIPLPVPYELPPQQYSSEDVPWSW 634

Query: 720  DRQYKKRDVFGQVWP*KIK 776
            DR+Y K+DV+GQVWP K++
Sbjct: 635  DRRYGKKDVYGQVWPRKVQ 653


>ref|XP_010655352.1| PREDICTED: tyrosyl-DNA phosphodiesterase 1 isoform X1 [Vitis
            vinifera]
 emb|CBI23170.3| unnamed protein product, partial [Vitis vinifera]
          Length = 678

 Score =  409 bits (1050), Expect = e-135
 Identities = 195/255 (76%), Positives = 222/255 (87%), Gaps = 1/255 (0%)
 Frame = +3

Query: 3    MKLRSILKECVFDKEFQNSPLIYQFSSLGSLDEKWMTEFAFSMSSGVSDDKKPLGLGEPL 182
            MKL S+L+EC+FDKEFQ SPL YQFSSLGSLDEKWMTE A SMSSG  DDK PLGLG+PL
Sbjct: 414  MKLCSVLQECIFDKEFQKSPLAYQFSSLGSLDEKWMTELASSMSSGSCDDKTPLGLGKPL 473

Query: 183  IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWAKWKASHSGRCRAMPHIKTFTR 362
            I+WPTVED+RCSLEGYAAG+ +PSPQKNVEK FLKKYWAKWKA+H+GRCRAMPHIKT+TR
Sbjct: 474  IIWPTVEDVRCSLEGYAAGNAIPSPQKNVEKEFLKKYWAKWKATHTGRCRAMPHIKTYTR 533

Query: 363  YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSSATQAHAFSCTENGS 542
            YNGQNLAWFLLTS+NLSKAAWGALQKNN+QLMIRSYELGVLFLPS   +   FSCT+NGS
Sbjct: 534  YNGQNLAWFLLTSANLSKAAWGALQKNNSQLMIRSYELGVLFLPSPINRGQGFSCTDNGS 593

Query: 543  TSENKCGPSLKTPEAKRTKLVSLASIHSKRMD-LPDVITLPVPYELPPQRYSSEDVPWSW 719
             S+NKCG S  T +++RTKLV+L    ++  D   +VI LPVPYELPP++YSSEDVPWSW
Sbjct: 594  PSKNKCGLSENT-KSQRTKLVTLTWEGNRSSDSSSEVIPLPVPYELPPKQYSSEDVPWSW 652

Query: 720  DRQYKKRDVFGQVWP 764
            DR+Y K+DV GQVWP
Sbjct: 653  DRRYYKKDVCGQVWP 667


>ref|XP_016432676.1| PREDICTED: tyrosyl-DNA phosphodiesterase 1-like [Nicotiana tabacum]
          Length = 261

 Score =  393 bits (1010), Expect = e-135
 Identities = 187/258 (72%), Positives = 217/258 (84%)
 Frame = +3

Query: 3   MKLRSILKECVFDKEFQNSPLIYQFSSLGSLDEKWMTEFAFSMSSGVSDDKKPLGLGEPL 182
           MKLR+IL+EC F KEFQ SPLIYQFSSLGSLDEKW+ E A SMS+GVS+DKKPLG+GEPL
Sbjct: 1   MKLRTILQECTFSKEFQKSPLIYQFSSLGSLDEKWLAELASSMSAGVSEDKKPLGIGEPL 60

Query: 183 IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWAKWKASHSGRCRAMPHIKTFTR 362
           IVWP+VED+RCSLEGYAAG+ VPSP KNVEK FLKKYWA+WKASH+GRCRAMPHIKTF R
Sbjct: 61  IVWPSVEDVRCSLEGYAAGNAVPSPLKNVEKEFLKKYWARWKASHTGRCRAMPHIKTFLR 120

Query: 363 YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSSATQAHAFSCTENGS 542
           YNGQ+LAW LLTSSNLSKAAWG+LQKNN+QLMIRSYELGVLFLPSS  +   FSCT+NG 
Sbjct: 121 YNGQSLAWLLLTSSNLSKAAWGSLQKNNSQLMIRSYELGVLFLPSSVKRGCGFSCTDNGY 180

Query: 543 TSENKCGPSLKTPEAKRTKLVSLASIHSKRMDLPDVITLPVPYELPPQRYSSEDVPWSWD 722
           +SE++        E  R KLV+LA       D  +V+ LPVPYELPP+ YS+ED+PWSWD
Sbjct: 181 SSEDE----TSMHEGNRIKLVTLAWQGKGNDDYSEVLKLPVPYELPPKPYSAEDIPWSWD 236

Query: 723 RQYKKRDVFGQVWP*KIK 776
           R+Y K+DV+GQVWP ++K
Sbjct: 237 RRYTKKDVYGQVWPRQVK 254


>ref|XP_017231366.1| PREDICTED: tyrosyl-DNA phosphodiesterase 1 isoform X2 [Daucus carota
            subsp. sativus]
          Length = 597

 Score =  403 bits (1035), Expect = e-134
 Identities = 189/258 (73%), Positives = 224/258 (86%)
 Frame = +3

Query: 3    MKLRSILKECVFDKEFQNSPLIYQFSSLGSLDEKWMTEFAFSMSSGVSDDKKPLGLGEPL 182
            MKLR++L+E +FD++F+ +PL+YQFSSLGSLDEKWMTE A SMSSGVS+D++PLGLG+PL
Sbjct: 336  MKLRTVLQESIFDQQFRKAPLVYQFSSLGSLDEKWMTELASSMSSGVSEDQQPLGLGQPL 395

Query: 183  IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWAKWKASHSGRCRAMPHIKTFTR 362
            I+WP+VED+RCSLEGYAAG+ +PSPQKNVEK FLKKYWAKWKA HSGRC AMPHIKTF R
Sbjct: 396  IIWPSVEDVRCSLEGYAAGNAIPSPQKNVEKEFLKKYWAKWKARHSGRCHAMPHIKTFAR 455

Query: 363  YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSSATQAHAFSCTENGS 542
            YNGQ+LAWFLLTSSNLSKAAWGALQKNN+QLMIRSYELGVLFLPS      +FSCT+NG+
Sbjct: 456  YNGQDLAWFLLTSSNLSKAAWGALQKNNSQLMIRSYELGVLFLPSK-PHGCSFSCTDNGN 514

Query: 543  TSENKCGPSLKTPEAKRTKLVSLASIHSKRMDLPDVITLPVPYELPPQRYSSEDVPWSWD 722
             SE KC       EA+RTKLV+L+   +K   + +VITLPVPYELPPQRYSSED+PWSWD
Sbjct: 515  QSEGKC-EMANNSEAERTKLVTLSWEGNKNTKISEVITLPVPYELPPQRYSSEDIPWSWD 573

Query: 723  RQYKKRDVFGQVWP*KIK 776
            R+Y K+DV GQVWP +++
Sbjct: 574  RRYNKKDVHGQVWPRQVQ 591


>ref|XP_017231364.1| PREDICTED: tyrosyl-DNA phosphodiesterase 1 isoform X1 [Daucus carota
            subsp. sativus]
 ref|XP_017231365.1| PREDICTED: tyrosyl-DNA phosphodiesterase 1 isoform X1 [Daucus carota
            subsp. sativus]
          Length = 657

 Score =  403 bits (1035), Expect = e-133
 Identities = 189/258 (73%), Positives = 224/258 (86%)
 Frame = +3

Query: 3    MKLRSILKECVFDKEFQNSPLIYQFSSLGSLDEKWMTEFAFSMSSGVSDDKKPLGLGEPL 182
            MKLR++L+E +FD++F+ +PL+YQFSSLGSLDEKWMTE A SMSSGVS+D++PLGLG+PL
Sbjct: 396  MKLRTVLQESIFDQQFRKAPLVYQFSSLGSLDEKWMTELASSMSSGVSEDQQPLGLGQPL 455

Query: 183  IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWAKWKASHSGRCRAMPHIKTFTR 362
            I+WP+VED+RCSLEGYAAG+ +PSPQKNVEK FLKKYWAKWKA HSGRC AMPHIKTF R
Sbjct: 456  IIWPSVEDVRCSLEGYAAGNAIPSPQKNVEKEFLKKYWAKWKARHSGRCHAMPHIKTFAR 515

Query: 363  YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSSATQAHAFSCTENGS 542
            YNGQ+LAWFLLTSSNLSKAAWGALQKNN+QLMIRSYELGVLFLPS      +FSCT+NG+
Sbjct: 516  YNGQDLAWFLLTSSNLSKAAWGALQKNNSQLMIRSYELGVLFLPSK-PHGCSFSCTDNGN 574

Query: 543  TSENKCGPSLKTPEAKRTKLVSLASIHSKRMDLPDVITLPVPYELPPQRYSSEDVPWSWD 722
             SE KC       EA+RTKLV+L+   +K   + +VITLPVPYELPPQRYSSED+PWSWD
Sbjct: 575  QSEGKC-EMANNSEAERTKLVTLSWEGNKNTKISEVITLPVPYELPPQRYSSEDIPWSWD 633

Query: 723  RQYKKRDVFGQVWP*KIK 776
            R+Y K+DV GQVWP +++
Sbjct: 634  RRYNKKDVHGQVWPRQVQ 651


>gb|PIN03584.1| Phosphodiesterase I [Handroanthus impetiginosus]
          Length = 376

 Score =  392 bits (1007), Expect = e-133
 Identities = 182/258 (70%), Positives = 219/258 (84%)
 Frame = +3

Query: 3   MKLRSILKECVFDKEFQNSPLIYQFSSLGSLDEKWMTEFAFSMSSGVSDDKKPLGLGEPL 182
           MKLR++L+EC F+K+F+ SPLIYQFSSLGSLDEKWM+E A S+S+G++DDKKPLGLG+P+
Sbjct: 113 MKLRTVLQECTFEKQFEKSPLIYQFSSLGSLDEKWMSELATSVSAGMTDDKKPLGLGKPM 172

Query: 183 IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWAKWKASHSGRCRAMPHIKTFTR 362
           I+WP+VED+RCSLEGYAAG+ +PSP KNVEK FLKKYWAKW AS +GRCRAMPHIKTFTR
Sbjct: 173 IIWPSVEDVRCSLEGYAAGNAIPSPLKNVEKEFLKKYWAKWNASQTGRCRAMPHIKTFTR 232

Query: 363 YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSSATQAHAFSCTENGS 542
           YNGQNLAW LLTSSNLSKAAWGALQKNN+QLMIRSYELGVLFLP S     AFSCT++  
Sbjct: 233 YNGQNLAWLLLTSSNLSKAAWGALQKNNSQLMIRSYELGVLFLPCSGKYIRAFSCTDDAH 292

Query: 543 TSENKCGPSLKTPEAKRTKLVSLASIHSKRMDLPDVITLPVPYELPPQRYSSEDVPWSWD 722
            SE K  PS ++ E K+ KLV+LA   ++  +  +VI LPVPYELPP+ YS +DVPWSWD
Sbjct: 293 ISEGK-SPSSRSSEVKQKKLVTLACNENRNNESSEVIQLPVPYELPPKPYSPQDVPWSWD 351

Query: 723 RQYKKRDVFGQVWP*KIK 776
           R+Y ++DV+GQVWP  +K
Sbjct: 352 RRYTEKDVYGQVWPRPVK 369


>ref|XP_015067766.1| PREDICTED: tyrosyl-DNA phosphodiesterase 1 [Solanum pennellii]
          Length = 645

 Score =  401 bits (1030), Expect = e-133
 Identities = 191/254 (75%), Positives = 214/254 (84%)
 Frame = +3

Query: 3    MKLRSILKECVFDKEFQNSPLIYQFSSLGSLDEKWMTEFAFSMSSGVSDDKKPLGLGEPL 182
            MKLR++L+EC F KEFQ SPLIYQFSSLGSLDEKWMTEFA SMS+GV+DDKKPLG+GEP+
Sbjct: 395  MKLRTVLQECTFSKEFQKSPLIYQFSSLGSLDEKWMTEFASSMSAGVTDDKKPLGIGEPM 454

Query: 183  IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWAKWKASHSGRCRAMPHIKTFTR 362
            IVWP VED+RCSLEGYAAGS +PSP KNVEK FLKKYWAKWKASH+GRCRAMPHIKTF R
Sbjct: 455  IVWPNVEDVRCSLEGYAAGSAIPSPSKNVEKEFLKKYWAKWKASHTGRCRAMPHIKTFLR 514

Query: 363  YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSSATQAHAFSCTENGS 542
            YNGQ+LAWFLLTSSNLSKAAWGALQKNN+QLMIRSYELGVLFLPSS  +   FSCT NG 
Sbjct: 515  YNGQSLAWFLLTSSNLSKAAWGALQKNNSQLMIRSYELGVLFLPSSVKRGCGFSCTNNGF 574

Query: 543  TSENKCGPSLKTPEAKRTKLVSLASIHSKRMDLPDVITLPVPYELPPQRYSSEDVPWSWD 722
             SE++        E K+ KLV+LA       D  +VI LPVPYELPP+ YS ED+PWSWD
Sbjct: 575  PSEDE----TSIHEGKKIKLVTLAWQGKGNDDSSEVIKLPVPYELPPKPYSLEDIPWSWD 630

Query: 723  RQYKKRDVFGQVWP 764
            R+Y KRD++GQVWP
Sbjct: 631  RRYTKRDIYGQVWP 644


>ref|XP_010240926.1| PREDICTED: tyrosyl-DNA phosphodiesterase 1 isoform X2 [Nelumbo
            nucifera]
          Length = 653

 Score =  399 bits (1025), Expect = e-132
 Identities = 191/256 (74%), Positives = 218/256 (85%), Gaps = 2/256 (0%)
 Frame = +3

Query: 3    MKLRSILKECVFDKEFQNSPLIYQFSSLGSLDEKWMTEFAFSMSSGVSDDKKPLGLGEPL 182
            MKLR++L+EC+FDKEF+NSPL+YQFSSLGSLDEKWM+E A SMSSG+SDDK PLGLG+PL
Sbjct: 397  MKLRTVLQECIFDKEFKNSPLVYQFSSLGSLDEKWMSELALSMSSGLSDDKMPLGLGKPL 456

Query: 183  IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWAKWKASHSGRCRAMPHIKTFTR 362
            IVWPTVED+RCSLEGYAAGS +PSPQKNVEK FLKKYWA+WKASH+GRCRAMPHIKTFTR
Sbjct: 457  IVWPTVEDVRCSLEGYAAGSAIPSPQKNVEKEFLKKYWARWKASHTGRCRAMPHIKTFTR 516

Query: 363  YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSSATQAH-AFSCTENG 539
            YNGQNLAWFLLTS+NLSKAAWGALQKNN+QLMIRSYELGVLFLPS +   +  FSCT+NG
Sbjct: 517  YNGQNLAWFLLTSANLSKAAWGALQKNNSQLMIRSYELGVLFLPSVSKDHYCGFSCTDNG 576

Query: 540  STSENKCGPSLKTPEAKRTKLVSLA-SIHSKRMDLPDVITLPVPYELPPQRYSSEDVPWS 716
             T ++    S    +  RTKLV+L    +       +VI LPVPYELPPQ YS EDVPWS
Sbjct: 577  DTIKDLHKSSETNTQGHRTKLVTLRWQGNQSSNSSSEVIQLPVPYELPPQPYSPEDVPWS 636

Query: 717  WDRQYKKRDVFGQVWP 764
            WDR+Y K+DV+GQVWP
Sbjct: 637  WDRRYYKKDVYGQVWP 652


>ref|XP_006343414.2| PREDICTED: tyrosyl-DNA phosphodiesterase 1 [Solanum tuberosum]
          Length = 646

 Score =  398 bits (1022), Expect = e-131
 Identities = 189/254 (74%), Positives = 213/254 (83%)
 Frame = +3

Query: 3    MKLRSILKECVFDKEFQNSPLIYQFSSLGSLDEKWMTEFAFSMSSGVSDDKKPLGLGEPL 182
            MKLR+IL+EC F KEFQ SPLIYQFSSLGSLDEKWMTEFA SMS+GV+DDKKPLG+GEP+
Sbjct: 396  MKLRTILQECTFSKEFQKSPLIYQFSSLGSLDEKWMTEFASSMSAGVTDDKKPLGIGEPM 455

Query: 183  IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWAKWKASHSGRCRAMPHIKTFTR 362
            IVWP VED+RCSLEGYAAGS +PSP KNVEK FLKKYWA+WKASH+GRCRAMPHIKTF R
Sbjct: 456  IVWPNVEDVRCSLEGYAAGSAIPSPSKNVEKEFLKKYWARWKASHTGRCRAMPHIKTFLR 515

Query: 363  YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSSATQAHAFSCTENGS 542
            YNGQ+LAWFLLTSSNLSKAAWG LQKNN+QLMIRSYELGVLFLPSS  +   FSCT NG 
Sbjct: 516  YNGQSLAWFLLTSSNLSKAAWGTLQKNNSQLMIRSYELGVLFLPSSVKRGCGFSCTNNGY 575

Query: 543  TSENKCGPSLKTPEAKRTKLVSLASIHSKRMDLPDVITLPVPYELPPQRYSSEDVPWSWD 722
             SE++        E K+ KLV+LA       D  +VI LPVPYELPP+ YS ED+PWSWD
Sbjct: 576  PSEDE----TSMHEGKKIKLVTLAWQGKGNDDSSEVIKLPVPYELPPKPYSPEDIPWSWD 631

Query: 723  RQYKKRDVFGQVWP 764
            R+Y K+D++GQVWP
Sbjct: 632  RRYTKKDIYGQVWP 645


>gb|OMO76723.1| hypothetical protein CCACVL1_15470 [Corchorus capsularis]
          Length = 871

 Score =  404 bits (1037), Expect = e-131
 Identities = 197/255 (77%), Positives = 218/255 (85%), Gaps = 1/255 (0%)
 Frame = +3

Query: 3    MKLRSILKECVFDKEFQNSPLIYQFSSLGSLDEKWMTEFAFSMSSGVSDDKKPLGLGEPL 182
            MKLR++L+ECVFDKEFQ SPL+YQFSSLGSLDEKWM E A SMSSG S+DK PLGLGEPL
Sbjct: 618  MKLRTVLQECVFDKEFQRSPLVYQFSSLGSLDEKWMAELASSMSSGYSEDKTPLGLGEPL 677

Query: 183  IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWAKWKASHSGRCRAMPHIKTFTR 362
            I+WPTVED+RCSLEGYAAGS +PSP KNVEKAFLKKYWAKWKASH+GRCRAMPHIKTFTR
Sbjct: 678  IIWPTVEDVRCSLEGYAAGSAIPSPIKNVEKAFLKKYWAKWKASHTGRCRAMPHIKTFTR 737

Query: 363  YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSSA-TQAHAFSCTENG 539
            YNGQ LAWFLLTS+NLSKAAWGALQKNN+QLMIRSYELGVLFLPS    +   FSCT NG
Sbjct: 738  YNGQRLAWFLLTSANLSKAAWGALQKNNSQLMIRSYELGVLFLPSDVKEEGGEFSCTSNG 797

Query: 540  STSENKCGPSLKTPEAKRTKLVSLASIHSKRMDLPDVITLPVPYELPPQRYSSEDVPWSW 719
             + + KCGPS    EA +TKLV+LA   SK     +VI LPVPYELPP+ YSSEDVPWS 
Sbjct: 798  GSGKGKCGPS-GNSEATKTKLVTLAWQGSK---TSEVIQLPVPYELPPKPYSSEDVPWSG 853

Query: 720  DRQYKKRDVFGQVWP 764
            DR+Y K+DV+GQVWP
Sbjct: 854  DRRYSKKDVYGQVWP 868


>gb|PKI40197.1| hypothetical protein CRG98_039390 [Punica granatum]
          Length = 438

 Score =  390 bits (1001), Expect = e-131
 Identities = 187/256 (73%), Positives = 215/256 (83%), Gaps = 2/256 (0%)
 Frame = +3

Query: 3   MKLRSILKECVFDKEFQNSPLIYQFSSLGSLDEKWMTEFAFSMSSGVSDDKKPLGLGEPL 182
           MKLRS+L+EC FDKEFQ +PLIYQFSSLGSLDEKWM E A SMS+G S+DKKPLGLG+P 
Sbjct: 173 MKLRSVLQECTFDKEFQKAPLIYQFSSLGSLDEKWMAELASSMSAGSSEDKKPLGLGDPQ 232

Query: 183 IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWAKWKASHSGRCRAMPHIKTFTR 362
           I+WPTVED+RCSLEGYAAG+ +P P KNVEK FLKKYWAKWKA+H+GRCRAMPHIKT+TR
Sbjct: 233 IIWPTVEDVRCSLEGYAAGNAIPGPLKNVEKEFLKKYWAKWKANHTGRCRAMPHIKTYTR 292

Query: 363 YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSS-ATQAHAFSCTENG 539
           Y GQ LAW LLTS+NLSKAAWGALQKNN+QLMIRSYELGVLFLP+S   + H FSCT  G
Sbjct: 293 YKGQKLAWLLLTSANLSKAAWGALQKNNSQLMIRSYELGVLFLPNSMRREGHVFSCTNGG 352

Query: 540 STSENKCGPSLKTPEAKRTKLVSLASIHSKRMDL-PDVITLPVPYELPPQRYSSEDVPWS 716
           + S+    PS +  E KRTKLV+L     ++ DL  +VI LPVPYELPP+ YSSEDVPWS
Sbjct: 353 TPSKGTGLPS-EESEVKRTKLVTLLGQGCEKTDLSSEVIPLPVPYELPPRPYSSEDVPWS 411

Query: 717 WDRQYKKRDVFGQVWP 764
           WDR+Y K+DV+GQVWP
Sbjct: 412 WDRRYNKKDVYGQVWP 427


>ref|XP_022870063.1| tyrosyl-DNA phosphodiesterase 1-like [Olea europaea var.
           sylvestris]
          Length = 483

 Score =  391 bits (1005), Expect = e-131
 Identities = 185/258 (71%), Positives = 217/258 (84%)
 Frame = +3

Query: 3   MKLRSILKECVFDKEFQNSPLIYQFSSLGSLDEKWMTEFAFSMSSGVSDDKKPLGLGEPL 182
           MKLR++L+EC F+KEF  SPL+ QFSSLGSLDEKWM E   SMS+GV+++KKPLGLG+PL
Sbjct: 220 MKLRTVLQECTFEKEFHMSPLVCQFSSLGSLDEKWMAELTASMSAGVTEEKKPLGLGKPL 279

Query: 183 IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWAKWKASHSGRCRAMPHIKTFTR 362
           I+WPTVED+RCSLEGYAAG+ +PSP KNVEK FLKKYWAKWKASH+GRC AMPHIKTFTR
Sbjct: 280 IIWPTVEDVRCSLEGYAAGNAIPSPVKNVEKEFLKKYWAKWKASHTGRCHAMPHIKTFTR 339

Query: 363 YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSSATQAHAFSCTENGS 542
           YNGQNLAWFLLTS+NLSKAAWGALQKN++QLMIRSYELGVLFLP S      FSCT NG+
Sbjct: 340 YNGQNLAWFLLTSANLSKAAWGALQKNSSQLMIRSYELGVLFLPFSGNHCCEFSCTYNGN 399

Query: 543 TSENKCGPSLKTPEAKRTKLVSLASIHSKRMDLPDVITLPVPYELPPQRYSSEDVPWSWD 722
            SE K   S +  E KRTKLV+LA   ++  +  +VI LP+PYELPP+ YSSEDVPWSWD
Sbjct: 400 HSEAK-SESSRRSEVKRTKLVTLAWKGNRNAESTEVIQLPIPYELPPKLYSSEDVPWSWD 458

Query: 723 RQYKKRDVFGQVWP*KIK 776
           RQY + DV+GQVWP +++
Sbjct: 459 RQYTQTDVYGQVWPRQVQ 476


>ref|XP_010317667.1| PREDICTED: tyrosyl-DNA phosphodiesterase 1 [Solanum lycopersicum]
          Length = 645

 Score =  397 bits (1019), Expect = e-131
 Identities = 189/254 (74%), Positives = 213/254 (83%)
 Frame = +3

Query: 3    MKLRSILKECVFDKEFQNSPLIYQFSSLGSLDEKWMTEFAFSMSSGVSDDKKPLGLGEPL 182
            MKLR++L+EC F KEFQ SPLIYQFSSLGSLDEKWMTEFA SMS+GV+DDKKPLG+GEP+
Sbjct: 395  MKLRTVLQECTFSKEFQKSPLIYQFSSLGSLDEKWMTEFASSMSAGVTDDKKPLGIGEPM 454

Query: 183  IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWAKWKASHSGRCRAMPHIKTFTR 362
            IVWP VED+RCSLEGYAAGS +PSP KNVEK FLKKYWAKWKASH+GRCRAMPHIKTF R
Sbjct: 455  IVWPNVEDVRCSLEGYAAGSAIPSPSKNVEKEFLKKYWAKWKASHTGRCRAMPHIKTFLR 514

Query: 363  YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSSATQAHAFSCTENGS 542
            YNGQ+LAWFLLTSSNLSKAAWGALQKNN+QLMIRSYELGVLFLPSS  +   FSCT NG 
Sbjct: 515  YNGQSLAWFLLTSSNLSKAAWGALQKNNSQLMIRSYELGVLFLPSSVKRGCGFSCTNNGY 574

Query: 543  TSENKCGPSLKTPEAKRTKLVSLASIHSKRMDLPDVITLPVPYELPPQRYSSEDVPWSWD 722
             SE++        E K+ KLV+LA       D  +VI LPV YELPP+ YS ED+PWSWD
Sbjct: 575  PSEDE----TSIHEGKKIKLVTLAWQGKGNDDSSEVIKLPVAYELPPKPYSLEDIPWSWD 630

Query: 723  RQYKKRDVFGQVWP 764
            R+Y K+D++GQVWP
Sbjct: 631  RRYTKKDIYGQVWP 644


>ref|XP_023920145.1| tyrosyl-DNA phosphodiesterase 1 [Quercus suber]
          Length = 658

 Score =  397 bits (1020), Expect = e-131
 Identities = 190/260 (73%), Positives = 219/260 (84%), Gaps = 2/260 (0%)
 Frame = +3

Query: 3    MKLRSILKECVFDKEFQNSPLIYQFSSLGSLDEKWMTEFAFSMSSGVSDDKKPLGLGEPL 182
            MKLR++L+EC FDK+F+NSPL YQFSSLGSLDEKW+ E  +SMSSG S+DK PLGLG+P 
Sbjct: 393  MKLRTVLQECTFDKDFKNSPLAYQFSSLGSLDEKWLAELTYSMSSGFSEDKTPLGLGQPR 452

Query: 183  IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWAKWKASHSGRCRAMPHIKTFTR 362
            I+WPTVED+RCSLEGYAAG+ +PSP KNVEK FLKKYWAKWKASH+GRCRAMPHIKTFTR
Sbjct: 453  IIWPTVEDVRCSLEGYAAGNAIPSPLKNVEKEFLKKYWAKWKASHTGRCRAMPHIKTFTR 512

Query: 363  YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSSATQ-AHAFSCTENG 539
            YNGQ LAW LLTSSNLSKAAWGALQKNN+QLMIRSYELGVLFLPSS  +    FSCT NG
Sbjct: 513  YNGQKLAWLLLTSSNLSKAAWGALQKNNSQLMIRSYELGVLFLPSSVERYGSGFSCTSNG 572

Query: 540  STSENKCGPSLKTPEAKRTKLVSLASIHSKRMD-LPDVITLPVPYELPPQRYSSEDVPWS 716
              +E+KC  SL+  E +RTKLV+L    S+  D   DVI LPVPYELPPQ Y+SEDVPWS
Sbjct: 573  DITEDKC-RSLENSEVRRTKLVTLTWQGSRNSDSSSDVIPLPVPYELPPQPYTSEDVPWS 631

Query: 717  WDRQYKKRDVFGQVWP*KIK 776
            WDR+Y K+DV+ QVWP +++
Sbjct: 632  WDRRYTKKDVYDQVWPRQVQ 651


>gb|POF00599.1| tyrosyl-dna phosphodiesterase 1 [Quercus suber]
          Length = 703

 Score =  397 bits (1020), Expect = e-130
 Identities = 190/260 (73%), Positives = 219/260 (84%), Gaps = 2/260 (0%)
 Frame = +3

Query: 3    MKLRSILKECVFDKEFQNSPLIYQFSSLGSLDEKWMTEFAFSMSSGVSDDKKPLGLGEPL 182
            MKLR++L+EC FDK+F+NSPL YQFSSLGSLDEKW+ E  +SMSSG S+DK PLGLG+P 
Sbjct: 438  MKLRTVLQECTFDKDFKNSPLAYQFSSLGSLDEKWLAELTYSMSSGFSEDKTPLGLGQPR 497

Query: 183  IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWAKWKASHSGRCRAMPHIKTFTR 362
            I+WPTVED+RCSLEGYAAG+ +PSP KNVEK FLKKYWAKWKASH+GRCRAMPHIKTFTR
Sbjct: 498  IIWPTVEDVRCSLEGYAAGNAIPSPLKNVEKEFLKKYWAKWKASHTGRCRAMPHIKTFTR 557

Query: 363  YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSSATQ-AHAFSCTENG 539
            YNGQ LAW LLTSSNLSKAAWGALQKNN+QLMIRSYELGVLFLPSS  +    FSCT NG
Sbjct: 558  YNGQKLAWLLLTSSNLSKAAWGALQKNNSQLMIRSYELGVLFLPSSVERYGSGFSCTSNG 617

Query: 540  STSENKCGPSLKTPEAKRTKLVSLASIHSKRMD-LPDVITLPVPYELPPQRYSSEDVPWS 716
              +E+KC  SL+  E +RTKLV+L    S+  D   DVI LPVPYELPPQ Y+SEDVPWS
Sbjct: 618  DITEDKC-RSLENSEVRRTKLVTLTWQGSRNSDSSSDVIPLPVPYELPPQPYTSEDVPWS 676

Query: 717  WDRQYKKRDVFGQVWP*KIK 776
            WDR+Y K+DV+ QVWP +++
Sbjct: 677  WDRRYTKKDVYDQVWPRQVQ 696


>ref|XP_020217732.1| tyrosyl-DNA phosphodiesterase 1 isoform X2 [Cajanus cajan]
          Length = 606

 Score =  394 bits (1011), Expect = e-130
 Identities = 188/256 (73%), Positives = 214/256 (83%), Gaps = 2/256 (0%)
 Frame = +3

Query: 3    MKLRSILKECVFDKEFQNSPLIYQFSSLGSLDEKWMTEFAFSMSSGVSDDKKPLGLGEPL 182
            MKLRS+L+EC FD+EF+ SPL+YQFSSLGSLDEKWM E A SMS+G+S+DK PLG+GEPL
Sbjct: 350  MKLRSLLQECTFDEEFKKSPLVYQFSSLGSLDEKWMAELASSMSAGLSEDKTPLGMGEPL 409

Query: 183  IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWAKWKASHSGRCRAMPHIKTFTR 362
            I+WPTVED+RCSLEGYAAGS +PSP KNVEKAFLKKYWAKWKA H+GRCRAMPHIKTF R
Sbjct: 410  IIWPTVEDVRCSLEGYAAGSAIPSPLKNVEKAFLKKYWAKWKADHTGRCRAMPHIKTFAR 469

Query: 363  YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSS-ATQAHAFSCTENG 539
            YN QNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSS       FSCT N 
Sbjct: 470  YNNQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSSFKRHGSVFSCTSNV 529

Query: 540  STSENKCGPSLKTPEAKRTKLVSLASIHSKRMDLPDV-ITLPVPYELPPQRYSSEDVPWS 716
            + SE+K  P+ +T E K+TKLV+L  +  +     +V I LP+PYELPP  YSS+D PWS
Sbjct: 530  AQSEDKI-PARETSEMKKTKLVTLTGLRGRMHSSSEVIIQLPLPYELPPMPYSSQDTPWS 588

Query: 717  WDRQYKKRDVFGQVWP 764
            WDRQY K+DV+G VWP
Sbjct: 589  WDRQYNKKDVYGNVWP 604


>gb|KYP67403.1| Tyrosyl-DNA phosphodiesterase 1 [Cajanus cajan]
          Length = 614

 Score =  394 bits (1011), Expect = e-130
 Identities = 188/256 (73%), Positives = 214/256 (83%), Gaps = 2/256 (0%)
 Frame = +3

Query: 3    MKLRSILKECVFDKEFQNSPLIYQFSSLGSLDEKWMTEFAFSMSSGVSDDKKPLGLGEPL 182
            MKLRS+L+EC FD+EF+ SPL+YQFSSLGSLDEKWM E A SMS+G+S+DK PLG+GEPL
Sbjct: 358  MKLRSLLQECTFDEEFKKSPLVYQFSSLGSLDEKWMAELASSMSAGLSEDKTPLGMGEPL 417

Query: 183  IVWPTVEDIRCSLEGYAAGSCVPSPQKNVEKAFLKKYWAKWKASHSGRCRAMPHIKTFTR 362
            I+WPTVED+RCSLEGYAAGS +PSP KNVEKAFLKKYWAKWKA H+GRCRAMPHIKTF R
Sbjct: 418  IIWPTVEDVRCSLEGYAAGSAIPSPLKNVEKAFLKKYWAKWKADHTGRCRAMPHIKTFAR 477

Query: 363  YNGQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSS-ATQAHAFSCTENG 539
            YN QNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSS       FSCT N 
Sbjct: 478  YNNQNLAWFLLTSSNLSKAAWGALQKNNTQLMIRSYELGVLFLPSSFKRHGSVFSCTSNV 537

Query: 540  STSENKCGPSLKTPEAKRTKLVSLASIHSKRMDLPDV-ITLPVPYELPPQRYSSEDVPWS 716
            + SE+K  P+ +T E K+TKLV+L  +  +     +V I LP+PYELPP  YSS+D PWS
Sbjct: 538  AQSEDKI-PARETSEMKKTKLVTLTGLRGRMHSSSEVIIQLPLPYELPPMPYSSQDTPWS 596

Query: 717  WDRQYKKRDVFGQVWP 764
            WDRQY K+DV+G VWP
Sbjct: 597  WDRQYNKKDVYGNVWP 612