BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Chrysanthemum22_contig00030057
         (1702 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_021977342.1| DNA topoisomerase 2-like [Helianthus annuus]...   743   0.0  
ref|XP_022005320.1| DNA topoisomerase 2-like [Helianthus annuus]...   740   0.0  
gb|KVI00753.1| Arginine repressor C-terminal-like domain-contain...   734   0.0  
ref|XP_023759895.1| DNA topoisomerase 2 [Lactuca sativa]              725   0.0  
gb|PLY88472.1| hypothetical protein LSAT_1X105720 [Lactuca sativa]    725   0.0  
ref|XP_019053336.1| PREDICTED: DNA topoisomerase 2-like [Nelumbo...   656   0.0  
ref|XP_008779357.2| PREDICTED: DNA topoisomerase 2 [Phoenix dact...   653   0.0  
ref|XP_020577441.1| DNA topoisomerase 2 [Phalaenopsis equestris]      652   0.0  
gb|PKA63063.1| DNA topoisomerase 2 [Apostasia shenzhenica]            650   0.0  
ref|XP_010920068.1| PREDICTED: DNA topoisomerase 2 [Elaeis guine...   648   0.0  
gb|AQK73815.1| DNA topoisomerase 2, partial [Zea mays]                621   0.0  
ref|XP_020703085.1| DNA topoisomerase 2-like [Dendrobium catenat...   639   0.0  
ref|XP_020693654.1| DNA topoisomerase 2 [Dendrobium catenatum] >...   643   0.0  
ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform ...   644   0.0  
ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform ...   644   0.0  
ref|XP_004308680.1| PREDICTED: DNA topoisomerase 2 [Fragaria ves...   642   0.0  
ref|XP_024173810.1| DNA topoisomerase 2-like isoform X2 [Rosa ch...   642   0.0  
ref|XP_024173808.1| DNA topoisomerase 2-like isoform X1 [Rosa ch...   642   0.0  
gb|OWM78385.1| hypothetical protein CDL15_Pgr016109 [Punica gran...   642   0.0  
ref|XP_010023597.1| PREDICTED: DNA topoisomerase 2 [Eucalyptus g...   640   0.0  

>ref|XP_021977342.1| DNA topoisomerase 2-like [Helianthus annuus]
 gb|OTG37224.1| putative topoisomerase II [Helianthus annuus]
          Length = 1499

 Score =  743 bits (1919), Expect = 0.0
 Identities = 395/597 (66%), Positives = 464/597 (77%), Gaps = 30/597 (5%)
 Frame = +1

Query: 1    MECLEDDTVALMKRRVVDLAGCLGNGVKVELDGKCVPVKTFEDYVKLY--PGTSTTRIYE 174
            MECLEDD VALMK+RVVDLAGCLG  VKVELDGK VP KTFEDYVKLY  P T T RIYE
Sbjct: 229  MECLEDDVVALMKKRVVDLAGCLGKSVKVELDGKRVPPKTFEDYVKLYLQPSTDTLRIYE 288

Query: 175  KVHDRWDICVCLSDGKFKQVSFLNYVATMKGGSQVDYITNQITGHLERVV-------NFE 333
            KV++RW+ICV ++DG F+QVSF+N +AT+KGG+ VDYITNQI  HL  VV       N +
Sbjct: 289  KVNERWEICVSIADGHFEQVSFVNNIATIKGGTHVDYITNQIANHLVTVVKKQNKHANLK 348

Query: 334  PDNIKSYLWVFVNA------FDSQTKENLTTTDKGIYGSACELTHEFLKRIAKPYLRKRL 495
              N+K+YLWVFVNA      FDSQTKE LT      +GS CEL+ EFLK++AK  + KR+
Sbjct: 349  AHNVKNYLWVFVNALIDNPAFDSQTKETLTIKQSS-FGSTCELSPEFLKKVAKSDIVKRV 407

Query: 496  SLLKDNPDNQYEGLKKTAGKRKGKLNIALLEDANMAATNKSRECTLILTQGDSAKAFAMS 675
              +      Q   LKKT G ++GKLNI  LE+AN AATN S  CTLILT+GDSAKA AMS
Sbjct: 408  --VSWVQFKQQNDLKKTDGNKRGKLNIPKLEEANFAATNNSDNCTLILTEGDSAKALAMS 465

Query: 676  GLAVLGQDYYGVLPLKDKLLNVREASHQKLQENTEIQNIKEILGLQDGKVYENVEELRYG 855
            GL+V+GQDYYGV PL+ KLLNVREAS ++LQEN EIQNIK+ILGLQ GK+Y+NV+ LRYG
Sbjct: 466  GLSVVGQDYYGVFPLRGKLLNVREASPKQLQENAEIQNIKKILGLQHGKIYDNVKSLRYG 525

Query: 856  HLMIMADEDHDGSRIKGLLINFFHTFWPSLLKVPHFMRAFI-----------KDVKWFYI 1002
            HLMIMAD+DHDGS IKGLLINF H+FWPSLLKVP F+  FI           K+V  FY 
Sbjct: 526  HLMIMADQDHDGSHIKGLLINFLHSFWPSLLKVPEFVLEFITPIVKATNKKTKNVISFYT 585

Query: 1003 MHEYVTSKVESLGNEATKYIIKYFKGLGTT--EDEAQYFG-FDHHIQDFVWANNEDHDAI 1173
            M EY   K E+LG++A +Y IKY+KGLGT+  ++ A+YF   + H +DFVWA++ED DAI
Sbjct: 586  MPEYEAWK-ENLGHKAREYKIKYYKGLGTSNGKEGAEYFADLEKHKKDFVWADDEDGDAI 644

Query: 1174 ELAFSKTKIEARMDWLRAPQAGTYTDSKKKSIRYRDFINEEFKQCVVADLRRSIPSVVDG 1353
            ELAFSK KIEAR +WLRA QAGT+ DSK+K I YRDFIN+E     +ADL+RSIPS+VDG
Sbjct: 645  ELAFSKKKIEARKNWLRALQAGTFFDSKEKHIPYRDFINKELILFSMADLQRSIPSMVDG 704

Query: 1354 LTRGQRKILFCAFKKPIIQEIKVAEFSHYVSEHSAYHHGEASLVGTIIGMAQNYVGSNNI 1533
            L  GQRKILFCAFKKPI QE+KVA+FS YVSEHSAYHHGE SLV TIIGMAQN++GSNNI
Sbjct: 705  LKPGQRKILFCAFKKPIFQEVKVAQFSGYVSEHSAYHHGEQSLVSTIIGMAQNFIGSNNI 764

Query: 1534 NLLQPIGQYGTRYMGGKDHADDRCIFTRLSPITRYLFYEADELCL-YLNDDGQSIEP 1701
            NL  P GQ+GTR MGGKDHA  R I+T+LSPITR+LF++ADEL L YLN+DGQSIEP
Sbjct: 765  NLFYPSGQFGTRQMGGKDHASGRYIYTKLSPITRHLFHKADELLLNYLNEDGQSIEP 821


>ref|XP_022005320.1| DNA topoisomerase 2-like [Helianthus annuus]
 gb|OTF98638.1| putative DNA topoisomerase 2 [Helianthus annuus]
          Length = 1488

 Score =  740 bits (1911), Expect = 0.0
 Identities = 396/597 (66%), Positives = 465/597 (77%), Gaps = 30/597 (5%)
 Frame = +1

Query: 1    MECLEDDTVALMKRRVVDLAGCLGNGVKVELDGKCVPVKTFEDYVKLY--PGTSTTRIYE 174
            MECLEDD VALMK+RVVDLAGCLG  VKVEL+GK VP KTFEDYVKLY  P T T RIYE
Sbjct: 216  MECLEDDVVALMKKRVVDLAGCLGKTVKVELNGKRVPPKTFEDYVKLYLQPSTDTLRIYE 275

Query: 175  KVHDRWDICVCLSDGKFKQVSFLNYVATMKGGSQVDYITNQITGHLERVV-------NFE 333
            KV++RW+ICV ++DG F+QVSF+N +AT+KGG+ VDYITNQI  HL  VV       N +
Sbjct: 276  KVNERWEICVSMADGHFEQVSFVNNIATIKGGTHVDYITNQIANHLVTVVKKQNKHANIK 335

Query: 334  PDNIKSYLWVFVNA------FDSQTKENLTTTDKGIYGSACELTHEFLKRIAKPYLRKRL 495
              N+K+YLWVFVNA      FDSQTKE LT      +GS CEL+ EFLK++AK  + KR+
Sbjct: 336  AHNVKNYLWVFVNALIDNPAFDSQTKETLTIKHSS-FGSTCELSLEFLKKVAKSDVVKRV 394

Query: 496  SLLKDNPDNQYEGLKKTAGKRKGKLNIALLEDANMAATNKSRECTLILTQGDSAKAFAMS 675
              +      Q   LKKT G ++GKLNI  LE+AN AAT+ S +CTLILT+GDSAKA AMS
Sbjct: 395  --MSWVQFKQQNDLKKTDGNKRGKLNIPKLEEANFAATSNSDKCTLILTEGDSAKALAMS 452

Query: 676  GLAVLGQDYYGVLPLKDKLLNVREASHQKLQENTEIQNIKEILGLQDGKVYENVEELRYG 855
            GL+V+GQDYYGV PL+ KLLNVREAS ++LQEN EIQNIK+ILGLQ GK Y+NV+ LRYG
Sbjct: 453  GLSVVGQDYYGVFPLRGKLLNVREASPKQLQENAEIQNIKKILGLQHGKTYDNVKSLRYG 512

Query: 856  HLMIMADEDHDGSRIKGLLINFFHTFWPSLLKVPHFMRAFI-----------KDVKWFYI 1002
            HLMIMAD+DHDGS IKGLLINF H+FWPSLLKVP F+  FI           K+V  FY 
Sbjct: 513  HLMIMADQDHDGSHIKGLLINFLHSFWPSLLKVPEFVLEFITPIVKATNKKTKNVISFYT 572

Query: 1003 MHEYVTSKVESLGNEATKYIIKYFKGLGTT--EDEAQYFG-FDHHIQDFVWANNEDHDAI 1173
            M EY   K E+LG++A +Y IKY+KGLGT+  ++ A+YF   + H +DFVWA++ED DAI
Sbjct: 573  MPEYENWK-ENLGHKAREYKIKYYKGLGTSNGKEGAEYFADLEKHKKDFVWADDEDGDAI 631

Query: 1174 ELAFSKTKIEARMDWLRAPQAGTYTDSKKKSIRYRDFINEEFKQCVVADLRRSIPSVVDG 1353
            ELAFSK KIEAR +WLRA QAGTY DSK+K I YRDFIN+E     +ADL+RSIPS+VDG
Sbjct: 632  ELAFSKKKIEARKNWLRALQAGTYFDSKEKHIPYRDFINKELILFSMADLQRSIPSMVDG 691

Query: 1354 LTRGQRKILFCAFKKPIIQEIKVAEFSHYVSEHSAYHHGEASLVGTIIGMAQNYVGSNNI 1533
            L  GQRKILFCAFKKPI QE+KVA+FS YVSEHSAYHHGE SLV TIIGMAQN+VGSNNI
Sbjct: 692  LKPGQRKILFCAFKKPIFQEVKVAQFSGYVSEHSAYHHGEQSLVSTIIGMAQNFVGSNNI 751

Query: 1534 NLLQPIGQYGTRYMGGKDHADDRCIFTRLSPITRYLFYEADELCL-YLNDDGQSIEP 1701
            NLL P GQ+GTR MGGKDHA  R I+TRLSPITR+LF++ADEL L +LN+DGQSIEP
Sbjct: 752  NLLYPSGQFGTRQMGGKDHASGRYIYTRLSPITRHLFHKADELLLNFLNEDGQSIEP 808


>gb|KVI00753.1| Arginine repressor C-terminal-like domain-containing protein [Cynara
            cardunculus var. scolymus]
          Length = 1484

 Score =  734 bits (1896), Expect = 0.0
 Identities = 395/597 (66%), Positives = 461/597 (77%), Gaps = 30/597 (5%)
 Frame = +1

Query: 1    MECLEDDTVALMKRRVVDLAGCLGNGVKVELDGKCVPVKTFEDYVKLYPGTS--TTRIYE 174
            MECLEDD VALMK+RVVDLAGCLG  VKVELDGK VP KTFEDYVKLY  +S  T R+YE
Sbjct: 229  MECLEDDVVALMKKRVVDLAGCLGKSVKVELDGKRVPPKTFEDYVKLYLPSSADTLRLYE 288

Query: 175  KVHDRWDICVCLSDGKFKQVSFLNYVATMKGGSQVDYITNQITGHLERVVN-------FE 333
            KV++RW+ICV ++DG F+QVSF+N +AT+KGG+ VDYITNQI  HL  VV         +
Sbjct: 289  KVNERWEICVSMADGHFEQVSFVNNIATIKGGTHVDYITNQIANHLVAVVKKQNKHATLK 348

Query: 334  PDNIKSYLWVFVNA------FDSQTKENLTTTDKGIYGSACELTHEFLKRIAKPYLRKRL 495
              N+K+YLWVFVNA      FDSQTKE LT      +GS CELT +FLK++AK  + KR+
Sbjct: 349  AHNVKNYLWVFVNALIDNPAFDSQTKETLTIKQSS-FGSTCELTPDFLKKVAKSDVVKRV 407

Query: 496  SLLKDNPDNQYEGLKKTAGKRKGKLNIALLEDANMAATNKSRECTLILTQGDSAKAFAMS 675
              +      Q   LKKT G ++GKLNI  LE+AN AAT+ S  CTLILT+GDSAKA AMS
Sbjct: 408  --VSWVQFKQQNDLKKTDGNKRGKLNIPKLEEANYAATSNSDNCTLILTEGDSAKALAMS 465

Query: 676  GLAVLGQDYYGVLPLKDKLLNVREASHQKLQENTEIQNIKEILGLQDGKVYENVEELRYG 855
            GL+V+GQD+YGV PL+ KLLNVREAS ++LQEN EIQNIK+ILGLQ  KVYENV+ LRYG
Sbjct: 466  GLSVVGQDFYGVFPLRGKLLNVREASPKQLQENAEIQNIKKILGLQQAKVYENVKSLRYG 525

Query: 856  HLMIMADEDHDGSRIKGLLINFFHTFWPSLLKVPHFMRAFI-----------KDVKWFYI 1002
            HLMIMAD+DHDGS IKGLLINF HTFWPSLLKVP+F+  FI           K+V  FY 
Sbjct: 526  HLMIMADQDHDGSHIKGLLINFLHTFWPSLLKVPNFVLEFITPIVKATNKRTKNVLSFYT 585

Query: 1003 MHEYVTSKVESLGNEATKYIIKYFKGLGTT--EDEAQYFG-FDHHIQDFVWANNEDHDAI 1173
            M EY   K E+LG+ A +Y IKY+KGLGT+  ++ A+YF   D H +DFVWA++ED +AI
Sbjct: 586  MPEYEGWK-ENLGHRAREYKIKYYKGLGTSNGKEGAEYFADLDKHKKDFVWADDEDGEAI 644

Query: 1174 ELAFSKTKIEARMDWLRAPQAGTYTDSKKKSIRYRDFINEEFKQCVVADLRRSIPSVVDG 1353
            ELAFSK KIEAR  WLRA QAGTY DSK+K I YRDFIN+E     +ADL+RSIPS+VDG
Sbjct: 645  ELAFSKKKIEARKTWLRALQAGTYFDSKEKHIPYRDFINKELILFSMADLQRSIPSMVDG 704

Query: 1354 LTRGQRKILFCAFKKPIIQEIKVAEFSHYVSEHSAYHHGEASLVGTIIGMAQNYVGSNNI 1533
            L  GQRKILFCAFKKPI QE+KVA+FS YVSEHSAYHHGE SLV TIIGMAQNYVGSNNI
Sbjct: 705  LKPGQRKILFCAFKKPIFQEVKVAQFSGYVSEHSAYHHGEQSLVSTIIGMAQNYVGSNNI 764

Query: 1534 NLLQPIGQYGTRYMGGKDHADDRCIFTRLSPITRYLFYEADELCL-YLNDDGQSIEP 1701
            NLL P GQ+GTR MGGKDHA  R I+T+LSPITR+LF ++DEL L YLN+DGQSIEP
Sbjct: 765  NLLYPSGQFGTRQMGGKDHASGRYIYTKLSPITRHLFQKSDELLLDYLNEDGQSIEP 821


>ref|XP_023759895.1| DNA topoisomerase 2 [Lactuca sativa]
          Length = 1508

 Score =  725 bits (1871), Expect = 0.0
 Identities = 393/597 (65%), Positives = 454/597 (76%), Gaps = 30/597 (5%)
 Frame = +1

Query: 1    MECLEDDTVALMKRRVVDLAGCLGNGVKVELDGKCVPVKTFEDYVKLYPGTSTT--RIYE 174
            MECLE D VALMK+RVVDLAGCLG  VKVELDGK VP KTFEDYVKLY  +S    RIYE
Sbjct: 230  MECLEADVVALMKKRVVDLAGCLGKSVKVELDGKRVPPKTFEDYVKLYLQSSQEPLRIYE 289

Query: 175  KVHDRWDICVCLSDGKFKQVSFLNYVATMKGGSQVDYITNQITGHLERVVN-------FE 333
            KV++RW+ICV ++DG F+QVSF+N +AT+KGG+ VDYITNQI  HL  VV         +
Sbjct: 290  KVNERWEICVSIADGHFEQVSFVNNIATIKGGTHVDYITNQIANHLVAVVKKQNKHATLK 349

Query: 334  PDNIKSYLWVFVNA------FDSQTKENLTTTDKGIYGSACELTHEFLKRIAKPYLRKRL 495
              N+K+YLWVFVNA      FDSQTKE LT      +GS CELT EFLK++AK  + K++
Sbjct: 350  AHNVKNYLWVFVNALIDNPAFDSQTKETLTIKQSS-FGSTCELTPEFLKKVAKSDIVKKV 408

Query: 496  SLLKDNPDNQYEGLKKTAGKRKGKLNIALLEDANMAATNKSRECTLILTQGDSAKAFAMS 675
              L      Q+  LKKT G ++GKLNI  LE+AN AATN S  CTLILT+GDSAKA AMS
Sbjct: 409  --LSWVQFKQHNDLKKTDGNKRGKLNIPKLEEANFAATNNSDNCTLILTEGDSAKALAMS 466

Query: 676  GLAVLGQDYYGVLPLKDKLLNVREASHQKLQENTEIQNIKEILGLQDGKVYENVEELRYG 855
            GL+V+GQDYYGV PLK KLLNVREAS ++LQEN EIQNIK+ILGLQ GK Y+NV+ LRYG
Sbjct: 467  GLSVVGQDYYGVFPLKGKLLNVREASPKQLQENAEIQNIKKILGLQHGKEYDNVKSLRYG 526

Query: 856  HLMIMADEDHDGSRIKGLLINFFHTFWPSLLKVPHFMRAFI-----------KDVKWFYI 1002
            HLMIMAD+DHDGS IKGLLINF HTFWPSLLK+  F+  FI            +V  FY 
Sbjct: 527  HLMIMADQDHDGSHIKGLLINFLHTFWPSLLKLSEFVLEFITPIVKATQKNSNNVISFYN 586

Query: 1003 MHEYVTSKVESLGNEATKYIIKYFKGLGTT--EDEAQYFG-FDHHIQDFVWANNEDHDAI 1173
            M EY   K ESLG     + IKY+KGLGT+  ++ A+YF   D H +DFVW N+ED DAI
Sbjct: 587  MPEYEAWK-ESLGCRVKNFKIKYYKGLGTSNGKEGAEYFADLDKHKKDFVWDNDEDGDAI 645

Query: 1174 ELAFSKTKIEARMDWLRAPQAGTYTDSKKKSIRYRDFINEEFKQCVVADLRRSIPSVVDG 1353
            ELAFSK KIEAR  WLRA QAGTY DS +K I YRDFIN+E     +ADL+RSIPS+VDG
Sbjct: 646  ELAFSKKKIEARKTWLRALQAGTYFDSNEKHIPYRDFINKELILFSMADLQRSIPSMVDG 705

Query: 1354 LTRGQRKILFCAFKKPIIQEIKVAEFSHYVSEHSAYHHGEASLVGTIIGMAQNYVGSNNI 1533
            L  GQRKILFCAFKKPI QE+KVA+FS YVSEHSAYHHGEASLVGTIIGMAQN+VGSNNI
Sbjct: 706  LKPGQRKILFCAFKKPIFQEVKVAQFSGYVSEHSAYHHGEASLVGTIIGMAQNFVGSNNI 765

Query: 1534 NLLQPIGQYGTRYMGGKDHADDRCIFTRLSPITRYLFYEADELCL-YLNDDGQSIEP 1701
            NLL P GQ+GTR MGGKDHA  R I+T+L+PITR+LF +ADEL L YL++DGQSIEP
Sbjct: 766  NLLYPSGQFGTRQMGGKDHASGRYIYTKLTPITRHLFNKADELLLNYLSEDGQSIEP 822


>gb|PLY88472.1| hypothetical protein LSAT_1X105720 [Lactuca sativa]
          Length = 1508

 Score =  725 bits (1871), Expect = 0.0
 Identities = 393/597 (65%), Positives = 454/597 (76%), Gaps = 30/597 (5%)
 Frame = +1

Query: 1    MECLEDDTVALMKRRVVDLAGCLGNGVKVELDGKCVPVKTFEDYVKLYPGTSTT--RIYE 174
            MECLE D VALMK+RVVDLAGCLG  VKVELDGK VP KTFEDYVKLY  +S    RIYE
Sbjct: 230  MECLEADVVALMKKRVVDLAGCLGKSVKVELDGKRVPPKTFEDYVKLYLQSSQEPLRIYE 289

Query: 175  KVHDRWDICVCLSDGKFKQVSFLNYVATMKGGSQVDYITNQITGHLERVVN-------FE 333
            KV++RW+ICV ++DG F+QVSF+N +AT+KGG+ VDYITNQI  HL  VV         +
Sbjct: 290  KVNERWEICVSIADGHFEQVSFVNNIATIKGGTHVDYITNQIANHLVAVVKKQNKHATLK 349

Query: 334  PDNIKSYLWVFVNA------FDSQTKENLTTTDKGIYGSACELTHEFLKRIAKPYLRKRL 495
              N+K+YLWVFVNA      FDSQTKE LT      +GS CELT EFLK++AK  + K++
Sbjct: 350  AHNVKNYLWVFVNALIDNPAFDSQTKETLTIKQSS-FGSTCELTPEFLKKVAKSDIVKKV 408

Query: 496  SLLKDNPDNQYEGLKKTAGKRKGKLNIALLEDANMAATNKSRECTLILTQGDSAKAFAMS 675
              L      Q+  LKKT G ++GKLNI  LE+AN AATN S  CTLILT+GDSAKA AMS
Sbjct: 409  --LSWVQFKQHNDLKKTDGNKRGKLNIPKLEEANFAATNNSDNCTLILTEGDSAKALAMS 466

Query: 676  GLAVLGQDYYGVLPLKDKLLNVREASHQKLQENTEIQNIKEILGLQDGKVYENVEELRYG 855
            GL+V+GQDYYGV PLK KLLNVREAS ++LQEN EIQNIK+ILGLQ GK Y+NV+ LRYG
Sbjct: 467  GLSVVGQDYYGVFPLKGKLLNVREASPKQLQENAEIQNIKKILGLQHGKEYDNVKSLRYG 526

Query: 856  HLMIMADEDHDGSRIKGLLINFFHTFWPSLLKVPHFMRAFI-----------KDVKWFYI 1002
            HLMIMAD+DHDGS IKGLLINF HTFWPSLLK+  F+  FI            +V  FY 
Sbjct: 527  HLMIMADQDHDGSHIKGLLINFLHTFWPSLLKLSEFVLEFITPIVKATQKNSNNVISFYN 586

Query: 1003 MHEYVTSKVESLGNEATKYIIKYFKGLGTT--EDEAQYFG-FDHHIQDFVWANNEDHDAI 1173
            M EY   K ESLG     + IKY+KGLGT+  ++ A+YF   D H +DFVW N+ED DAI
Sbjct: 587  MPEYEAWK-ESLGCRVKNFKIKYYKGLGTSNGKEGAEYFADLDKHKKDFVWDNDEDGDAI 645

Query: 1174 ELAFSKTKIEARMDWLRAPQAGTYTDSKKKSIRYRDFINEEFKQCVVADLRRSIPSVVDG 1353
            ELAFSK KIEAR  WLRA QAGTY DS +K I YRDFIN+E     +ADL+RSIPS+VDG
Sbjct: 646  ELAFSKKKIEARKTWLRALQAGTYFDSNEKHIPYRDFINKELILFSMADLQRSIPSMVDG 705

Query: 1354 LTRGQRKILFCAFKKPIIQEIKVAEFSHYVSEHSAYHHGEASLVGTIIGMAQNYVGSNNI 1533
            L  GQRKILFCAFKKPI QE+KVA+FS YVSEHSAYHHGEASLVGTIIGMAQN+VGSNNI
Sbjct: 706  LKPGQRKILFCAFKKPIFQEVKVAQFSGYVSEHSAYHHGEASLVGTIIGMAQNFVGSNNI 765

Query: 1534 NLLQPIGQYGTRYMGGKDHADDRCIFTRLSPITRYLFYEADELCL-YLNDDGQSIEP 1701
            NLL P GQ+GTR MGGKDHA  R I+T+L+PITR+LF +ADEL L YL++DGQSIEP
Sbjct: 766  NLLYPSGQFGTRQMGGKDHASGRYIYTKLTPITRHLFNKADELLLNYLSEDGQSIEP 822


>ref|XP_019053336.1| PREDICTED: DNA topoisomerase 2-like [Nelumbo nucifera]
          Length = 1471

 Score =  656 bits (1693), Expect = 0.0
 Identities = 354/602 (58%), Positives = 443/602 (73%), Gaps = 35/602 (5%)
 Frame = +1

Query: 1    MECLEDDTVALMKRRVVDLAGCLGNGVKVELDGKCVPVKTFEDYVKLYPGT-------ST 159
            M  LEDD +ALMK+RV+DLAGCLG  VKVEL+G+ VPVK+F DYV LY  +       S 
Sbjct: 228  MTHLEDDVLALMKKRVIDLAGCLGKTVKVELNGQRVPVKSFLDYVNLYLQSASKTRPESL 287

Query: 160  TRIYEKVHDRWDICVCLSDGKFKQVSFLNYVATMKGGSQVDYITNQITGHLERVVNFEPD 339
             RI EKV++RW+ICV LS+G+F+QVSF+N +AT+KGG+ VDY+TNQIT H+  +VN +  
Sbjct: 288  PRITEKVNERWEICVSLSEGQFQQVSFVNGIATIKGGTHVDYVTNQITNHVMTIVNKKNK 347

Query: 340  N-------IKSYLWVFVNA------FDSQTKENLTTTDKGIYGSACELTHEFLKRIAKPY 480
            N       +K++LWVFVNA      FDSQTKE LTT     +GS CEL+ EFLK++AK  
Sbjct: 348  NANLKAHTVKNHLWVFVNALIDNPAFDSQTKETLTTRQNS-FGSKCELSQEFLKKVAKSG 406

Query: 481  LRKRLSLLKDNPDNQYEGLKKTAGKRKGKLN-IALLEDANMAATNKSRECTLILTQGDSA 657
            + + L    D    Q + LKKT G ++ ++  I  LEDAN A    S +CTLILT+GDSA
Sbjct: 407  VVENLLSWADF--KQSKDLKKTDGAKRQRITGITKLEDANDAGGKNSEKCTLILTEGDSA 464

Query: 658  KAFAMSGLAVLGQDYYGVLPLKDKLLNVREASHQKLQENTEIQNIKEILGLQDGKVYENV 837
            KA AM+G++V+G+++YGV PL+ KLLNVREA+H+++ EN EIQNIK+ILGLQ GK Y++V
Sbjct: 465  KALAMAGISVVGRNHYGVFPLRGKLLNVREANHKQIMENAEIQNIKQILGLQHGKEYDSV 524

Query: 838  EELRYGHLMIMADEDHDGSRIKGLLINFFHTFWPSLLKVPHFMRAFIKDVKW-------- 993
            + LRYGHLMIM D+DHDGS IKGLLINF HTFWPSLLK+P F+  FI  V          
Sbjct: 525  KSLRYGHLMIMTDQDHDGSHIKGLLINFIHTFWPSLLKIPSFLVEFITPVVKAIHKNGRV 584

Query: 994  --FYIMHEYVTSKVESLGNEATKYIIKYFKGLGTT--EDEAQYF-GFDHHIQDFVWANNE 1158
              FY M EY + K ESL   A+ + IKY+KGLGT+  ++  +YF   D H +DF+W N +
Sbjct: 585  LSFYSMPEYESWK-ESLAGNASGWSIKYYKGLGTSTSKEGKEYFKDLDMHKKDFIWINEQ 643

Query: 1159 DHDAIELAFSKTKIEARMDWLRAPQAGTYTDSKKKSIRYRDFINEEFKQCVVADLRRSIP 1338
            D DAIELAFSK KIEAR +WLR  + GTY D K+K I+Y DF+N+E     +ADL+RSIP
Sbjct: 644  DGDAIELAFSKKKIEARKNWLRNFEPGTYLDQKEKFIKYSDFVNKELILFSMADLQRSIP 703

Query: 1339 SVVDGLTRGQRKILFCAFKKPIIQEIKVAEFSHYVSEHSAYHHGEASLVGTIIGMAQNYV 1518
            S+VDGL  GQRKILFCAFK+  I+E KVA+FS YVSEHSAYHHGE SL+ TIIGMAQ+YV
Sbjct: 704  SMVDGLKPGQRKILFCAFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLMSTIIGMAQDYV 763

Query: 1519 GSNNINLLQPIGQYGTRYMGGKDHADDRCIFTRLSPITRYLFYEADELCL-YLNDDGQSI 1695
            GSNNINL QP GQ+GTR+ GGKDHA  R I+TRLSPITR+LF + D++ L YLN+DGQSI
Sbjct: 764  GSNNINLFQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDILLDYLNEDGQSI 823

Query: 1696 EP 1701
            EP
Sbjct: 824  EP 825


>ref|XP_008779357.2| PREDICTED: DNA topoisomerase 2 [Phoenix dactylifera]
          Length = 1378

 Score =  653 bits (1685), Expect = 0.0
 Identities = 350/603 (58%), Positives = 439/603 (72%), Gaps = 36/603 (5%)
 Frame = +1

Query: 1    MECLEDDTVALMKRRVVDLAGCLGNGVKVELDGKCVPVKTFEDYVKLYPGTSTT------ 162
            M  LEDD  ALMK+RVVDLAG LG  VKVEL+G+ +PVK+F DYV LY  + +       
Sbjct: 128  MTHLEDDVAALMKKRVVDLAGTLGKSVKVELNGQRIPVKSFSDYVNLYLQSVSKSRPEPL 187

Query: 163  -RIYEKVHDRWDICVCLSDGKFKQVSFLNYVATMKGGSQVDYITNQITGHLERVVN---- 327
             RI EKV+DRW+ICV LS+G+F+QVSF+N +AT KGG+ V+Y+TNQIT H+  +VN    
Sbjct: 188  PRISEKVNDRWEICVSLSEGQFQQVSFVNGIATTKGGTHVEYVTNQITSHVMNIVNKKNK 247

Query: 328  ---FEPDNIKSYLWVFVNA------FDSQTKENLTTTDKGIYGSACELTHEFLKRIAKPY 480
                +  N++S+LWVFVNA      FDSQTKE LTT  +G +GS CEL+ EFLK++AK  
Sbjct: 248  NANLKAHNVRSHLWVFVNALIDNPAFDSQTKETLTTR-QGSFGSKCELSQEFLKKVAKSG 306

Query: 481  LRKRLSLLKDNPDNQYEGLKKTAGKRKGKLN-IALLEDANMAATNKSRECTLILTQGDSA 657
            +    SLL      Q + LKKT G ++ ++  I  LEDAN A    S +CTLILT+GDSA
Sbjct: 307  VVN--SLLSWADFKQSKELKKTDGTKRQRITGIPKLEDANDAGGRNSEKCTLILTEGDSA 364

Query: 658  KAFAMSGLAVLGQDYYGVLPLKDKLLNVREASHQKLQENTEIQNIKEILGLQDGKVYENV 837
            KA AM+G++V+G++YYGV PL+ KLLNVREASH+++ EN EIQNIK+ILGLQ GK Y++ 
Sbjct: 365  KALAMAGISVVGRNYYGVFPLRGKLLNVREASHKQIMENAEIQNIKQILGLQHGKEYDST 424

Query: 838  EELRYGHLMIMADEDHDGSRIKGLLINFFHTFWPSLLKVPHFMRAFI-----------KD 984
            + LRYGHLMIM D+DHDGS IKGLLINF H+FWPSLLK+P FM  FI           K 
Sbjct: 425  KGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFMVEFITPIVKATHSKNKT 484

Query: 985  VKWFYIMHEYVTSKVESLGNEATKYIIKYFKGLGTT---EDEAQYFGFDHHIQDFVWANN 1155
            V  FY M EY   K E LG  A+ + IKY+KGLGT+   E +  +   D H +DF+W ++
Sbjct: 485  VLPFYSMPEYEAWK-ERLGGNASGWSIKYYKGLGTSTSKEGKEYFHDIDKHKKDFIWVDD 543

Query: 1156 EDHDAIELAFSKTKIEARMDWLRAPQAGTYTDSKKKSIRYRDFINEEFKQCVVADLRRSI 1335
            +D DAIELAFSK KIEAR +WLR  + GTY D ++K I+Y DF+N+E     +ADL+RSI
Sbjct: 544  QDGDAIELAFSKKKIEARKNWLRHFETGTYLDQRQKHIKYSDFVNKELILFSMADLQRSI 603

Query: 1336 PSVVDGLTRGQRKILFCAFKKPIIQEIKVAEFSHYVSEHSAYHHGEASLVGTIIGMAQNY 1515
            PS VDGL  GQRKILFC+FK+  ++E KVA+FS YVSEHSAYHHGE SL  TIIGMAQ++
Sbjct: 604  PSTVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDF 663

Query: 1516 VGSNNINLLQPIGQYGTRYMGGKDHADDRCIFTRLSPITRYLFYEADELCL-YLNDDGQS 1692
            VGSNNINLLQP GQ+GTR+ GGKDHA  R I+TRLSP+TR+LF + D++ L YLN+DGQS
Sbjct: 664  VGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPLTRFLFPKDDDMLLDYLNEDGQS 723

Query: 1693 IEP 1701
            IEP
Sbjct: 724  IEP 726


>ref|XP_020577441.1| DNA topoisomerase 2 [Phalaenopsis equestris]
          Length = 1468

 Score =  652 bits (1683), Expect = 0.0
 Identities = 349/603 (57%), Positives = 442/603 (73%), Gaps = 36/603 (5%)
 Frame = +1

Query: 1    MECLEDDTVALMKRRVVDLAGCLGNGVKVELDGKCVPVKTFEDYVKLYPGTSTT------ 162
            M+ LE+D VALMK+RVVDLAG LG  VKV+L+GK VPVKTF DYV LY  T++       
Sbjct: 232  MDHLEEDVVALMKKRVVDLAGTLGKTVKVDLNGKRVPVKTFGDYVNLYLQTASKSRSEPL 291

Query: 163  -RIYEKVHDRWDICVCLSDGKFKQVSFLNYVATMKGGSQVDYITNQITGHLERVVN---- 327
             RI EKV+DRW+IC+ LSDG+F+QVSF+N + T+KGG+ V+Y+T+QI  H+  +VN    
Sbjct: 292  PRIVEKVNDRWEICISLSDGQFQQVSFVNSINTIKGGTHVEYVTSQIASHVMSIVNKKNK 351

Query: 328  ---FEPDNIKSYLWVFVN------AFDSQTKENLTTTDKGIYGSACELTHEFLKRIAKPY 480
                +P N+KS+LWVFVN      AFDSQTKE LTT  +G +GS C+L+ +FLK++AK  
Sbjct: 352  NANLKPHNVKSHLWVFVNCLIDNPAFDSQTKETLTTR-QGSFGSKCDLSQDFLKKVAKSG 410

Query: 481  LRKRLSLLKDNPDNQYEGLKKTAGKRKGKLN-IALLEDANMAATNKSRECTLILTQGDSA 657
            + + L    D    Q++ LKKT G ++ K+  I+ L+DAN A    S +CTLILT+GDSA
Sbjct: 411  IVENLLSWADF--KQHKELKKTDGAKRQKITGISKLDDANDAGGKHSDKCTLILTEGDSA 468

Query: 658  KAFAMSGLAVLGQDYYGVLPLKDKLLNVREASHQKLQENTEIQNIKEILGLQDGKVYENV 837
            KA AM G+AV+G+DYYGV PL+ KLLNVREASH+++ EN EIQNIK+ILGLQ GK Y++V
Sbjct: 469  KALAMGGIAVVGRDYYGVFPLRGKLLNVREASHKQIMENAEIQNIKQILGLQQGKQYDSV 528

Query: 838  EELRYGHLMIMADEDHDGSRIKGLLINFFHTFWPSLLKVPHFMRAFIKD----------- 984
            + LRYGHLMIM D+DHDGS IKGLLINF HTFWPSLLK+P F+  FI             
Sbjct: 529  KGLRYGHLMIMTDQDHDGSHIKGLLINFIHTFWPSLLKIPSFLVEFITPIVKATYKKTGK 588

Query: 985  VKWFYIMHEYVTSKVESLGNEATKYIIKYFKGLGTT--EDEAQYF-GFDHHIQDFVWANN 1155
            V  FY M EY   K ESL   A+ + IKY+KGLGT+  ++  +YF     H +DFVW++ 
Sbjct: 589  VTSFYTMPEYEAWK-ESLRGNASSWSIKYYKGLGTSTSQEGKEYFQDLQRHKKDFVWSDE 647

Query: 1156 EDHDAIELAFSKTKIEARMDWLRAPQAGTYTDSKKKSIRYRDFINEEFKQCVVADLRRSI 1335
            +D DAIELAFSK KIEAR +WLR  + GT+ D  +K I Y DF+N+E     +ADL+RSI
Sbjct: 648  QDGDAIELAFSKKKIEARKNWLRQFEPGTHLDQNEKLISYSDFVNKELILFSMADLQRSI 707

Query: 1336 PSVVDGLTRGQRKILFCAFKKPIIQEIKVAEFSHYVSEHSAYHHGEASLVGTIIGMAQNY 1515
            PS+VDGL  GQRKILFC+FK+  ++E+K+ +F+ YVSEHSAYHHGE SL  TIIGMAQ++
Sbjct: 708  PSMVDGLKPGQRKILFCSFKRNFVKELKIGQFAGYVSEHSAYHHGEQSLATTIIGMAQDF 767

Query: 1516 VGSNNINLLQPIGQYGTRYMGGKDHADDRCIFTRLSPITRYLFYEADELCL-YLNDDGQS 1692
            VGSNNINLLQP GQ+GTR+ GGKDHA  R I+T+LSPITR+LF + D+L L YL DDGQS
Sbjct: 768  VGSNNINLLQPNGQFGTRHQGGKDHASARYIYTKLSPITRFLFPKEDDLVLDYLTDDGQS 827

Query: 1693 IEP 1701
            IEP
Sbjct: 828  IEP 830


>gb|PKA63063.1| DNA topoisomerase 2 [Apostasia shenzhenica]
          Length = 1404

 Score =  650 bits (1676), Expect = 0.0
 Identities = 351/603 (58%), Positives = 443/603 (73%), Gaps = 36/603 (5%)
 Frame = +1

Query: 1    MECLEDDTVALMKRRVVDLAGCLGNGVKVELDGKCVPVKTFEDYVKLYPGTSTT------ 162
            M  LE D VALMK+RVVD+AG +G  VKVEL+G+ +PVK F DYV LY  +++T      
Sbjct: 231  MSFLEADVVALMKKRVVDIAGAIGKTVKVELNGQRLPVKNFTDYVNLYLQSASTSRLEPL 290

Query: 163  -RIYEKVHDRWDICVCLSDGKFKQVSFLNYVATMKGGSQVDYITNQITGHLERVVN---- 327
             RIYEKV+DRW+ICV LSDG+F+QVSF+N + T+KGGS V+Y+TNQIT H+  +VN    
Sbjct: 291  PRIYEKVNDRWEICVSLSDGQFQQVSFVNAINTIKGGSHVEYVTNQITSHVITIVNKKNK 350

Query: 328  ---FEPDNIKSYLWVFVNA------FDSQTKENLTTTDKGIYGSACELTHEFLKRIAKPY 480
                +P  ++++LWVFVNA      FDSQTKE LTT  +G +GS CEL+ +FLK+++K  
Sbjct: 351  HANLKPHIVRNHLWVFVNALIDNPAFDSQTKETLTTR-QGCFGSKCELSQDFLKKVSKSG 409

Query: 481  LRKRLSLLKDNPDNQYEGLKKTAGKRKGKLN-IALLEDANMAATNKSRECTLILTQGDSA 657
            +    SLL      Q + LKKT G ++ K+  I  L+DAN A    S +CTLILT+GDSA
Sbjct: 410  IVD--SLLSWADFKQSKELKKTDGTKRQKITGITKLDDANDAGGKNSDKCTLILTEGDSA 467

Query: 658  KAFAMSGLAVLGQDYYGVLPLKDKLLNVREASHQKLQENTEIQNIKEILGLQDGKVYENV 837
            KA AM+G++V+G+++YGV PL+ KLLNVREASH+++ +N EIQNIK+ILGLQ GK Y++V
Sbjct: 468  KALAMAGISVVGRNHYGVFPLRGKLLNVREASHKQIMDNAEIQNIKQILGLQHGKQYDSV 527

Query: 838  EELRYGHLMIMADEDHDGSRIKGLLINFFHTFWPSLLKVPHFMRAFIKD----------- 984
              LRYGHLMIM D+DHDGS IKGLLINF H+FWPSLLK+P F+  FI             
Sbjct: 528  NGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPTFLVEFITPIVKATNNRNGK 587

Query: 985  VKWFYIMHEYVTSKVESLGNEATKYIIKYFKGLGTT--EDEAQYFGFDH-HIQDFVWANN 1155
            V  FY M EY   K ESLG  AT + +KY+KGLGT+  ++  +YF   H H +DF+WAN+
Sbjct: 588  VLSFYTMPEYEAWK-ESLGGNATGWSVKYYKGLGTSTSKEGKEYFQDIHKHKKDFLWAND 646

Query: 1156 EDHDAIELAFSKTKIEARMDWLRAPQAGTYTDSKKKSIRYRDFINEEFKQCVVADLRRSI 1335
            +D DAIELAFSK KIEAR +WLR  + GTY D K K I Y DF+N+E     +ADL+RSI
Sbjct: 647  QDGDAIELAFSKKKIEARKNWLRQFEPGTYLDQKGKLISYSDFVNKELILFSLADLQRSI 706

Query: 1336 PSVVDGLTRGQRKILFCAFKKPIIQEIKVAEFSHYVSEHSAYHHGEASLVGTIIGMAQNY 1515
            PS+VDGL  GQRKILFC+FK+  I+E+KVA+FS YVSEHSAYHHGE SL  TIIGMAQ++
Sbjct: 707  PSMVDGLKPGQRKILFCSFKRNFIKEMKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDF 766

Query: 1516 VGSNNINLLQPIGQYGTRYMGGKDHADDRCIFTRLSPITRYLFYEADELCL-YLNDDGQS 1692
            VGSNNINLLQP GQ+GTR+ GGKDHA  R I+T LSP+TR+LF + D+L L YLN+DGQS
Sbjct: 767  VGSNNINLLQPSGQFGTRHQGGKDHASARYIYTCLSPMTRFLFPKEDDLILDYLNEDGQS 826

Query: 1693 IEP 1701
            IEP
Sbjct: 827  IEP 829


>ref|XP_010920068.1| PREDICTED: DNA topoisomerase 2 [Elaeis guineensis]
          Length = 1486

 Score =  648 bits (1671), Expect = 0.0
 Identities = 350/603 (58%), Positives = 444/603 (73%), Gaps = 36/603 (5%)
 Frame = +1

Query: 1    MECLEDDTVALMKRRVVDLAGCLGNGVKVELDGKCVPVKTFEDYVKLYPGTSTT------ 162
            M  LEDD VALMK+RVVDLAG LG  VKVEL+G+ +PVK+F DYV LY  +++       
Sbjct: 230  MTHLEDDVVALMKKRVVDLAGILGKSVKVELNGQRIPVKSFGDYVNLYLQSASKSRPEPL 289

Query: 163  -RIYEKVHDRWDICVCLSDGKFKQVSFLNYVATMKGGSQVDYITNQITGHLERVVN---- 327
             RI EKV+DRW+IC  LS+G+F+QVSF+N +AT+KGG+ V+Y+TNQIT H+  +VN    
Sbjct: 290  PRISEKVNDRWEICASLSEGQFQQVSFVNGIATVKGGTHVEYVTNQITSHVMSIVNKKNK 349

Query: 328  ---FEPDNIKSYLWVFVNA------FDSQTKENLTTTDKGIYGSACELTHEFLKRIAKPY 480
                +  N++S+LWVFVNA      FDSQTKE LTT  +G +GS CEL+ EFLK++AK  
Sbjct: 350  NANLKAHNVRSHLWVFVNALIDNPAFDSQTKETLTTR-QGSFGSKCELSQEFLKKVAKSG 408

Query: 481  LRKRLSLLKDNPDNQYEGLKKTAG-KRKGKLNIALLEDANMAATNKSRECTLILTQGDSA 657
            +    SLL      Q + LKKT G KR+  + I  LEDAN A    S +CTLILT+GDSA
Sbjct: 409  VVN--SLLSWADFKQSKELKKTDGTKRQRIVGIPKLEDANDAGGRNSEKCTLILTEGDSA 466

Query: 658  KAFAMSGLAVLGQDYYGVLPLKDKLLNVREASHQKLQENTEIQNIKEILGLQDGKVYENV 837
            KA AM+G++V+G+++YGV PL+ KLLNVREASH+++ +N EIQ+IK+ILGLQ GK YE+ 
Sbjct: 467  KALAMAGISVVGRNHYGVFPLRGKLLNVREASHKQIMDNAEIQSIKQILGLQQGKEYEST 526

Query: 838  EELRYGHLMIMADEDHDGSRIKGLLINFFHTFWPSLLKVPHFMRAFI-----------KD 984
            + LRYGHLMIM D+DHDGS IKGLLINF H+FWPSLLK+P FM  FI           K+
Sbjct: 527  KGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFMVEFITPIVKATHNRNKN 586

Query: 985  VKWFYIMHEYVTSKVESLGNEATKYIIKYFKGLGTT--EDEAQYF-GFDHHIQDFVWANN 1155
            V  FY M EY   K ESLG  A+ + IKY+KGLGT+  ++  +YF     H +DF+W +N
Sbjct: 587  VLPFYSMPEYEAWK-ESLGGNASGWSIKYYKGLGTSTSKEGKEYFQDIVKHKKDFMWVDN 645

Query: 1156 EDHDAIELAFSKTKIEARMDWLRAPQAGTYTDSKKKSIRYRDFINEEFKQCVVADLRRSI 1335
            +D DAIELAFSK KIEAR +WLR  + GTY D ++K I+Y DF+N+E     +ADL+RSI
Sbjct: 646  QDGDAIELAFSKKKIEARKNWLRQFEPGTYLDQREKLIKYSDFVNKELILFSMADLQRSI 705

Query: 1336 PSVVDGLTRGQRKILFCAFKKPIIQEIKVAEFSHYVSEHSAYHHGEASLVGTIIGMAQNY 1515
            PS+VDGL  GQRKILFC+FK+  ++E KVA+F+ YVSEHSAYHHGE SL  TIIGMAQ++
Sbjct: 706  PSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFAGYVSEHSAYHHGEQSLASTIIGMAQDF 765

Query: 1516 VGSNNINLLQPIGQYGTRYMGGKDHADDRCIFTRLSPITRYLFYEADELCL-YLNDDGQS 1692
            VGSNNINLLQP GQ+GTR+ GGKDHA  R I+TRLSP+TR+LF + D++ L YLN+DGQ 
Sbjct: 766  VGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPLTRFLFPKDDDILLDYLNEDGQL 825

Query: 1693 IEP 1701
            IEP
Sbjct: 826  IEP 828


>gb|AQK73815.1| DNA topoisomerase 2, partial [Zea mays]
          Length = 739

 Score =  621 bits (1602), Expect = 0.0
 Identities = 336/601 (55%), Positives = 433/601 (72%), Gaps = 34/601 (5%)
 Frame = +1

Query: 1    MECLEDDTVALMKRRVVDLAGCLGNGVKVELDGKCVPVKTFEDYVKLYPGTSTT------ 162
            M  LEDD VALM++RVVD+AG LG  VKVELDG+ VP+K+F DYV LY  ++        
Sbjct: 128  MTHLEDDVVALMRKRVVDMAGTLGKTVKVELDGQRVPIKSFCDYVDLYMKSANCDRPDNF 187

Query: 163  -RIYEKVHDRWDICVCLSDGKFKQVSFLNYVATMKGGSQVDYITNQITGHLERVVN---- 327
             RIYE+V+DRW++CV  S+G+F+QVSF+N +AT++GGS VDY+TNQI  H+  +VN    
Sbjct: 188  KRIYEQVNDRWEVCVSQSEGQFQQVSFVNRIATIRGGSHVDYVTNQIANHVVAIVNKKNK 247

Query: 328  ---FEPDNIKSYLWVFVNA------FDSQTKENLTTTDKGIYGSACELTHEFLKRIAKPY 480
                +  N+KS+LWVFVNA      FDSQTKE LTT  +G +GS CEL+ +FLK++ K  
Sbjct: 248  NANMKLHNVKSHLWVFVNALIDNPAFDSQTKETLTTR-QGSFGSKCELSSDFLKKVEKSG 306

Query: 481  LRKRLSLLKDNPDNQYEGLKKTAGKRKGKLN-IALLEDANMAATNKSRECTLILTQGDSA 657
            + + +    D   ++   LKKT G +K +++ I  LEDAN A    S +CTLILT+GDSA
Sbjct: 307  VIENVLSWADFKLSKE--LKKTDGSKKSRISGIPKLEDANEAGGKDSDKCTLILTEGDSA 364

Query: 658  KAFAMSGLAVLGQDYYGVLPLKDKLLNVREASHQKLQENTEIQNIKEILGLQDGKVYENV 837
            KA AMSG+AV+G+DYYGV PL+ KLLNVREA+H+++ +N EIQ+IK+ILGLQ GK YE+ 
Sbjct: 365  KALAMSGIAVVGRDYYGVFPLRGKLLNVREANHKQIMDNAEIQHIKQILGLQHGKQYEST 424

Query: 838  EELRYGHLMIMADEDHDGSRIKGLLINFFHTFWPSLLKVPHFMRAFIKDV---------K 990
            + LRYGHLMIM D+DHDGS IKGLLINF H+FWPSLLKVP F+  FI  +         K
Sbjct: 425  KGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIIKATRGQTTK 484

Query: 991  WFYIMHEYVTSKVESLGNEATKYIIKYFKGLGTT--EDEAQYF-GFDHHIQDFVWANNED 1161
             FY M EY   + ++LG  A+ + IKY+KGLGT+  ++  +YF     H +DFVW +++D
Sbjct: 485  SFYTMPEYEEWR-KNLGASASSWTIKYYKGLGTSTAKEGRKYFEDIIDHKKDFVWVDDQD 543

Query: 1162 HDAIELAFSKTKIEARMDWLRAPQAGTYTDSKKKSIRYRDFINEEFKQCVVADLRRSIPS 1341
             + IELAFSK +I  R  WL   Q GTY D ++K ++Y DFIN+E     +ADL+RSIPS
Sbjct: 544  GNHIELAFSKKRIADRKQWLTNFQPGTYIDQREKQVKYSDFINKELILFSMADLQRSIPS 603

Query: 1342 VVDGLTRGQRKILFCAFKKPIIQEIKVAEFSHYVSEHSAYHHGEASLVGTIIGMAQNYVG 1521
            +VDGL  GQRKILFC+FK+  ++E KVA+FS YVSEHSAYHHGE SL  TIIGMAQN+VG
Sbjct: 604  MVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQNFVG 663

Query: 1522 SNNINLLQPIGQYGTRYMGGKDHADDRCIFTRLSPITRYLFYEADELCL-YLNDDGQSIE 1698
            SNNINL+ P GQ+GTR  GGKD A  R IFT+LS ITR +F + D++ L YLN+DGQSIE
Sbjct: 664  SNNINLMSPNGQFGTRAQGGKDAASPRYIFTKLSNITRSIFPKDDDILLNYLNEDGQSIE 723

Query: 1699 P 1701
            P
Sbjct: 724  P 724


>ref|XP_020703085.1| DNA topoisomerase 2-like [Dendrobium catenatum]
 gb|PKU64218.1| DNA topoisomerase 2 [Dendrobium catenatum]
          Length = 1268

 Score =  639 bits (1647), Expect = 0.0
 Identities = 343/602 (56%), Positives = 442/602 (73%), Gaps = 35/602 (5%)
 Frame = +1

Query: 1    MECLEDDTVALMKRRVVDLAGCLGNGVKVELDGKCVPVKTFEDYVKLYPGTSTT------ 162
            M+ LE+D VALMK+RVVDLAG LG  VKVEL+GK +PVKTF DYV LY  +++       
Sbjct: 32   MDHLEEDVVALMKKRVVDLAGTLGKTVKVELNGKRLPVKTFADYVNLYLQSASKSRPEPL 91

Query: 163  -RIYEKVHDRWDICVCLSDGKFKQVSFLNYVATMKGGSQVDYITNQITGHLERVVN---- 327
             RI EKV+DRW+ICV L+DG+F+QVSF+N + T+KGG+ V+Y+T+QI  H+  +VN    
Sbjct: 92   PRIAEKVNDRWEICVSLTDGQFQQVSFVNSINTIKGGTHVEYVTSQIASHVMSIVNKKNK 151

Query: 328  ---FEPDNIKSYLWVFVN------AFDSQTKENLTTTDKGIYGSACELTHEFLKRIAKPY 480
                 P N+K++LWVFVN      AFDSQTKE LTT  +G +GS C+L+ EFLK++AK  
Sbjct: 152  NANLRPHNVKNHLWVFVNCLIDNPAFDSQTKETLTTR-QGSFGSKCDLSQEFLKKVAKSG 210

Query: 481  LRKRLSLLKDNPDNQYEGLKKTAGKRKGKLN-IALLEDANMAATNKSRECTLILTQGDSA 657
            + +  SLL      Q + LKKT G ++ K++ I  L+DAN A    S +CTLILT+GDSA
Sbjct: 211  IVE--SLLSWADFKQNKELKKTDGTKRQKISGIVKLDDANDAGGKNSEKCTLILTEGDSA 268

Query: 658  KAFAMSGLAVLGQDYYGVLPLKDKLLNVREASHQKLQENTEIQNIKEILGLQDGKVYENV 837
            KA AM+G++V+G++ YGV PL+ KLLNVREASH+++ EN EIQNIK+ILGLQ GK YE+V
Sbjct: 269  KALAMAGISVVGRNNYGVFPLRGKLLNVREASHKQIMENAEIQNIKQILGLQQGKQYESV 328

Query: 838  EELRYGHLMIMADEDHDGSRIKGLLINFFHTFWPSLLKVPHFMRAFIKD----------V 987
            + LRYGHLMIM D+DHDGS IKGLLINF H+FWPSLLK+P F+  FI            V
Sbjct: 329  KGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATYRTGKV 388

Query: 988  KWFYIMHEYVTSKVESLGNEATKYIIKYFKGLGTT--EDEAQYF-GFDHHIQDFVWANNE 1158
              FY M EY + K ESL   A+ + IKY+KGLGT+  ++  +YF     H +DFVW + +
Sbjct: 389  LSFYTMPEYESWK-ESLRGNASGWSIKYYKGLGTSTSKEGKEYFQDLQKHKKDFVWFDEQ 447

Query: 1159 DHDAIELAFSKTKIEARMDWLRAPQAGTYTDSKKKSIRYRDFINEEFKQCVVADLRRSIP 1338
            D +AIELAFSK KIEAR +WLR  + GTY D  +K I Y DF+N+E     +ADL+RSIP
Sbjct: 448  DGEAIELAFSKKKIEARKNWLRQFEPGTYLDQNEKLISYSDFVNKELILFSMADLQRSIP 507

Query: 1339 SVVDGLTRGQRKILFCAFKKPIIQEIKVAEFSHYVSEHSAYHHGEASLVGTIIGMAQNYV 1518
            S++DGL  GQRKILFC+FK+  ++E K+++FS YVSEHSAYHHGE SL  TIIGMAQ++V
Sbjct: 508  SMLDGLKPGQRKILFCSFKRNFVKEAKISQFSGYVSEHSAYHHGEQSLASTIIGMAQDFV 567

Query: 1519 GSNNINLLQPIGQYGTRYMGGKDHADDRCIFTRLSPITRYLFYEADELCL-YLNDDGQSI 1695
            GSNNINLLQP GQ+GTR+ GGKDHA  R I+T+LSP+TR+LF + D+L L Y+++DGQSI
Sbjct: 568  GSNNINLLQPNGQFGTRHQGGKDHASARYIYTKLSPMTRFLFPKEDDLILDYMSEDGQSI 627

Query: 1696 EP 1701
            EP
Sbjct: 628  EP 629


>ref|XP_020693654.1| DNA topoisomerase 2 [Dendrobium catenatum]
 gb|PKU72193.1| DNA topoisomerase 2 [Dendrobium catenatum]
          Length = 1466

 Score =  643 bits (1658), Expect = 0.0
 Identities = 345/602 (57%), Positives = 443/602 (73%), Gaps = 35/602 (5%)
 Frame = +1

Query: 1    MECLEDDTVALMKRRVVDLAGCLGNGVKVELDGKCVPVKTFEDYVKLYPGTSTT------ 162
            M+ LE+D VALMK+RVVDLAG LG  VKVEL+GK +PVKTF DYV LY  +++       
Sbjct: 230  MDHLEEDVVALMKKRVVDLAGTLGKTVKVELNGKRLPVKTFADYVNLYLQSASKSRPEPL 289

Query: 163  -RIYEKVHDRWDICVCLSDGKFKQVSFLNYVATMKGGSQVDYITNQITGHLERVVN---- 327
             RI EKV+DRW+ICV L+DG+F+QVSF+N + T+KGG+ V+Y+T+QI  H+  +VN    
Sbjct: 290  PRIAEKVNDRWEICVSLTDGQFQQVSFVNSINTIKGGTHVEYVTSQIASHVMSIVNKKNK 349

Query: 328  ---FEPDNIKSYLWVFVN------AFDSQTKENLTTTDKGIYGSACELTHEFLKRIAKPY 480
                 P N+K++LWVFVN      AFDSQTKE LTT  +G +GS C+L+ EFLK++AK  
Sbjct: 350  NANLRPHNVKNHLWVFVNCLIDNPAFDSQTKETLTTR-QGSFGSKCDLSQEFLKKVAKSG 408

Query: 481  LRKRLSLLKDNPDNQYEGLKKTAGKRKGKLN-IALLEDANMAATNKSRECTLILTQGDSA 657
            + +  SLL      Q + LKKT G ++ K++ I  L+DAN A    S +CTLILT+GDSA
Sbjct: 409  IVE--SLLSWADFKQNKELKKTDGTKRQKISGIVKLDDANDAGGKNSEKCTLILTEGDSA 466

Query: 658  KAFAMSGLAVLGQDYYGVLPLKDKLLNVREASHQKLQENTEIQNIKEILGLQDGKVYENV 837
            KA AM+G++V+G++ YGV PL+ KLLNVREASH+++ EN EIQNIK+ILGLQ GK YE+V
Sbjct: 467  KALAMAGISVVGRNNYGVFPLRGKLLNVREASHKQIMENAEIQNIKQILGLQQGKEYESV 526

Query: 838  EELRYGHLMIMADEDHDGSRIKGLLINFFHTFWPSLLKVPHFMRAFIKD----------V 987
            + LRYGHLMIM D+DHDGS IKGLLINF H+FWPSLLK+P F+  FI            V
Sbjct: 527  KGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATYRTGKV 586

Query: 988  KWFYIMHEYVTSKVESLGNEATKYIIKYFKGLGTT--EDEAQYF-GFDHHIQDFVWANNE 1158
              FY M EY + K ESLG  A+ + IKY+KGLGT+  ++  +YF     H +DFVW + +
Sbjct: 587  LSFYTMPEYESWK-ESLGGNASGWSIKYYKGLGTSTSKEGKEYFQDLQKHKKDFVWFDEQ 645

Query: 1159 DHDAIELAFSKTKIEARMDWLRAPQAGTYTDSKKKSIRYRDFINEEFKQCVVADLRRSIP 1338
            D +AIELAFSK KIEAR +WLR  + GTY D  +K I Y DF+N+E     +ADL+RSIP
Sbjct: 646  DGEAIELAFSKKKIEARKNWLRQFEPGTYLDQNEKLISYSDFVNKELILFSMADLQRSIP 705

Query: 1339 SVVDGLTRGQRKILFCAFKKPIIQEIKVAEFSHYVSEHSAYHHGEASLVGTIIGMAQNYV 1518
            S+VDGL  GQRKILFC+FK+  ++E K+++FS YVSEHSAYHHGE SL  TIIGMAQ++V
Sbjct: 706  SMVDGLKPGQRKILFCSFKRNFVKEAKISQFSGYVSEHSAYHHGEQSLASTIIGMAQDFV 765

Query: 1519 GSNNINLLQPIGQYGTRYMGGKDHADDRCIFTRLSPITRYLFYEADELCL-YLNDDGQSI 1695
            GSNNINLLQP GQ+GTR+ GGKDHA  R I+T+LSP+TR+LF + D+L L Y+++DGQSI
Sbjct: 766  GSNNINLLQPNGQFGTRHQGGKDHASARYIYTKLSPMTRFLFPKEDDLILDYMSEDGQSI 825

Query: 1696 EP 1701
            EP
Sbjct: 826  EP 827


>ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform X2 [Nelumbo nucifera]
          Length = 1503

 Score =  644 bits (1660), Expect = 0.0
 Identities = 347/599 (57%), Positives = 440/599 (73%), Gaps = 35/599 (5%)
 Frame = +1

Query: 10   LEDDTVALMKRRVVDLAGCLGNGVKVELDGKCVPVKTFEDYVKLYPGTSTT-------RI 168
            LEDD VALMK+RV+DLAGCLG  VKVEL+G+ VPVK+F DYV LY  +++        RI
Sbjct: 231  LEDDVVALMKKRVIDLAGCLGKTVKVELNGQRVPVKSFLDYVNLYLQSASKSRPEPLPRI 290

Query: 169  YEKVHDRWDICVCLSDGKFKQVSFLNYVATMKGGSQVDYITNQITGHLERVVNFEPDN-- 342
             EKV +RW++CV LS+G+F+QVSF+N +AT+KGG+ VDY+TNQIT H+  +VN +  N  
Sbjct: 291  TEKVSERWEVCVSLSEGQFQQVSFVNGIATIKGGTHVDYVTNQITNHVMTIVNKKNKNAN 350

Query: 343  -----IKSYLWVFVN------AFDSQTKENLTTTDKGIYGSACELTHEFLKRIAKPYLRK 489
                 +K++LWVFVN      AFDSQTKE LTT     +GS CEL+ EFLK++AK  + +
Sbjct: 351  LKAHTVKNHLWVFVNSLIDNPAFDSQTKETLTTRQSS-FGSKCELSQEFLKKVAKSGVVE 409

Query: 490  RLSLLKDNPDNQYEGLKKTAGKRKGKLN-IALLEDANMAATNKSRECTLILTQGDSAKAF 666
             L    D    Q + LKKT G ++ ++  I  LEDAN A    S +CTLILT+GDSAKA 
Sbjct: 410  NLLSWADF--KQSKDLKKTDGAKRQRITGITKLEDANDAGGRNSEKCTLILTEGDSAKAL 467

Query: 667  AMSGLAVLGQDYYGVLPLKDKLLNVREASHQKLQENTEIQNIKEILGLQDGKVYENVEEL 846
            AM+G++V+G++ YGV PL+ KLLNVREA+H+++ +N EIQNIK+ILGLQ GK Y++V+ L
Sbjct: 468  AMAGISVVGRNNYGVFPLRGKLLNVREATHKQIMDNAEIQNIKQILGLQHGKEYDSVKSL 527

Query: 847  RYGHLMIMADEDHDGSRIKGLLINFFHTFWPSLLKVPHFMRAFIKD----------VKWF 996
            RYGHLMIM D+DHDGS IKGLLINF H+FWPSLLK+P F+  FI            V  F
Sbjct: 528  RYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHKNGKVLSF 587

Query: 997  YIMHEYVTSKVESLGNEATKYIIKYFKGLGTT--EDEAQYFGFDH-HIQDFVWANNEDHD 1167
            Y M EY + K   LG  A+ + IKY+KGLGT+  ++  +YF   H H +DF+W ++ D D
Sbjct: 588  YSMPEYESWKX--LGGNASGWSIKYYKGLGTSTSKEGKEYFKDLHKHKKDFLWVDDRDGD 645

Query: 1168 AIELAFSKTKIEARMDWLRAPQAGTYTDSKKKSIRYRDFINEEFKQCVVADLRRSIPSVV 1347
            AIELAFSK KIEAR +WLR  + GT  D K+K I+Y DF+N+E     +ADL+RSIPS+V
Sbjct: 646  AIELAFSKKKIEARKNWLRQFEPGTCLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMV 705

Query: 1348 DGLTRGQRKILFCAFKKPIIQEIKVAEFSHYVSEHSAYHHGEASLVGTIIGMAQNYVGSN 1527
            DGL  GQRKILFCAFK+ +I+E KVA+FS YVSEHSAYHHGE SL+ TIIGMAQ+YVGSN
Sbjct: 706  DGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAYHHGEQSLMSTIIGMAQDYVGSN 765

Query: 1528 NINLLQPIGQYGTRYMGGKDHADDRCIFTRLSPITRYLFYEADELCL-YLNDDGQSIEP 1701
            NINL QP GQ+GTR+ GGKDHA  R I+TRLSPITR+LF + D++ L YLN+DGQSIEP
Sbjct: 766  NINLFQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKGDDILLDYLNEDGQSIEP 824


>ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform X1 [Nelumbo nucifera]
          Length = 1504

 Score =  644 bits (1660), Expect = 0.0
 Identities = 347/599 (57%), Positives = 440/599 (73%), Gaps = 35/599 (5%)
 Frame = +1

Query: 10   LEDDTVALMKRRVVDLAGCLGNGVKVELDGKCVPVKTFEDYVKLYPGTSTT-------RI 168
            LEDD VALMK+RV+DLAGCLG  VKVEL+G+ VPVK+F DYV LY  +++        RI
Sbjct: 231  LEDDVVALMKKRVIDLAGCLGKTVKVELNGQRVPVKSFLDYVNLYLQSASKSRPEPLPRI 290

Query: 169  YEKVHDRWDICVCLSDGKFKQVSFLNYVATMKGGSQVDYITNQITGHLERVVNFEPDN-- 342
             EKV +RW++CV LS+G+F+QVSF+N +AT+KGG+ VDY+TNQIT H+  +VN +  N  
Sbjct: 291  TEKVSERWEVCVSLSEGQFQQVSFVNGIATIKGGTHVDYVTNQITNHVMTIVNKKNKNAN 350

Query: 343  -----IKSYLWVFVN------AFDSQTKENLTTTDKGIYGSACELTHEFLKRIAKPYLRK 489
                 +K++LWVFVN      AFDSQTKE LTT     +GS CEL+ EFLK++AK  + +
Sbjct: 351  LKAHTVKNHLWVFVNSLIDNPAFDSQTKETLTTRQSS-FGSKCELSQEFLKKVAKSGVVE 409

Query: 490  RLSLLKDNPDNQYEGLKKTAGKRKGKLN-IALLEDANMAATNKSRECTLILTQGDSAKAF 666
             L    D    Q + LKKT G ++ ++  I  LEDAN A    S +CTLILT+GDSAKA 
Sbjct: 410  NLLSWADF--KQSKDLKKTDGAKRQRITGITKLEDANDAGGRNSEKCTLILTEGDSAKAL 467

Query: 667  AMSGLAVLGQDYYGVLPLKDKLLNVREASHQKLQENTEIQNIKEILGLQDGKVYENVEEL 846
            AM+G++V+G++ YGV PL+ KLLNVREA+H+++ +N EIQNIK+ILGLQ GK Y++V+ L
Sbjct: 468  AMAGISVVGRNNYGVFPLRGKLLNVREATHKQIMDNAEIQNIKQILGLQHGKEYDSVKSL 527

Query: 847  RYGHLMIMADEDHDGSRIKGLLINFFHTFWPSLLKVPHFMRAFIKD----------VKWF 996
            RYGHLMIM D+DHDGS IKGLLINF H+FWPSLLK+P F+  FI            V  F
Sbjct: 528  RYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHKNGKVLSF 587

Query: 997  YIMHEYVTSKVESLGNEATKYIIKYFKGLGTT--EDEAQYFGFDH-HIQDFVWANNEDHD 1167
            Y M EY + K   LG  A+ + IKY+KGLGT+  ++  +YF   H H +DF+W ++ D D
Sbjct: 588  YSMPEYESWKX--LGGNASGWSIKYYKGLGTSTSKEGKEYFKDLHKHKKDFLWVDDRDGD 645

Query: 1168 AIELAFSKTKIEARMDWLRAPQAGTYTDSKKKSIRYRDFINEEFKQCVVADLRRSIPSVV 1347
            AIELAFSK KIEAR +WLR  + GT  D K+K I+Y DF+N+E     +ADL+RSIPS+V
Sbjct: 646  AIELAFSKKKIEARKNWLRQFEPGTCLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMV 705

Query: 1348 DGLTRGQRKILFCAFKKPIIQEIKVAEFSHYVSEHSAYHHGEASLVGTIIGMAQNYVGSN 1527
            DGL  GQRKILFCAFK+ +I+E KVA+FS YVSEHSAYHHGE SL+ TIIGMAQ+YVGSN
Sbjct: 706  DGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAYHHGEQSLMSTIIGMAQDYVGSN 765

Query: 1528 NINLLQPIGQYGTRYMGGKDHADDRCIFTRLSPITRYLFYEADELCL-YLNDDGQSIEP 1701
            NINL QP GQ+GTR+ GGKDHA  R I+TRLSPITR+LF + D++ L YLN+DGQSIEP
Sbjct: 766  NINLFQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKGDDILLDYLNEDGQSIEP 824


>ref|XP_004308680.1| PREDICTED: DNA topoisomerase 2 [Fragaria vesca subsp. vesca]
          Length = 1469

 Score =  642 bits (1657), Expect = 0.0
 Identities = 352/605 (58%), Positives = 436/605 (72%), Gaps = 38/605 (6%)
 Frame = +1

Query: 1    MECLEDDTVALMKRRVVDLAGCLGNGVKVELDGKCVPVKTFEDYVKLYPGTS-------T 159
            M  LE+D VALMK+RV+D+AGCLG  VKVEL+GK VPVK+F DYV LY  ++        
Sbjct: 224  MTYLEEDVVALMKKRVIDMAGCLGKTVKVELNGKRVPVKSFLDYVDLYLQSAGKSKDIKL 283

Query: 160  TRIYEKVHDRWDICVCLSDGKFKQVSFLNYVATMKGGSQVDYITNQITGHLERVVN---- 327
             R+ EKV+DRW+ICV LSDG+F+QVSF+N +AT+KGG+ VDY+TNQIT H+  VVN    
Sbjct: 284  PRMTEKVNDRWEICVSLSDGQFQQVSFVNSIATIKGGTHVDYVTNQITNHVMNVVNKKNK 343

Query: 328  ---FEPDNIKSYLWVFVNA------FDSQTKENLTTTDKGIYGSACELTHEFLKRIAKPY 480
                +  N+K+YLWVFVNA      FDSQTKE LT      +GS CEL  EFLK++AK  
Sbjct: 344  NANLKAHNVKNYLWVFVNALIDNPAFDSQTKETLTIRPSS-FGSKCELPQEFLKKVAKSG 402

Query: 481  LRKRL---SLLKDNPDNQYEGLKKTAGKRKGKL-NIALLEDANMAATNKSRECTLILTQG 648
            + + L   +  K+N D     LKKT G +  +L NI  LEDAN+A    S +CTLILT+G
Sbjct: 403  VVESLLSWANFKNNKD-----LKKTDGTKTERLHNINKLEDANLAGGRNSEKCTLILTEG 457

Query: 649  DSAKAFAMSGLAVLGQDYYGVLPLKDKLLNVREASHQKLQENTEIQNIKEILGLQDGKVY 828
            DSAKA AM+GLAV+G+D+YGV PL+ KLLNVREAS  +L++N EI+NIK+ILGLQ  K Y
Sbjct: 458  DSAKALAMAGLAVVGRDHYGVFPLRGKLLNVREASTTQLRDNEEIKNIKKILGLQQDKEY 517

Query: 829  ENVEELRYGHLMIMADEDHDGSRIKGLLINFFHTFWPSLLKVPHFMRAFIKDVKW----- 993
             N++ LRYGHLMIM D+DHDGS IKGLLINF H+FWPSLLKVP F+  FI  +       
Sbjct: 518  TNIKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHKN 577

Query: 994  -----FYIMHEYVTSKVESLGNEATKYIIKYFKGLGTT--EDEAQYF-GFDHHIQDFVWA 1149
                 FY M EY   + ESL   A+ + IKY+KGLGT+  ++   YF   D H +DFVW 
Sbjct: 578  GKELAFYSMPEYEAWR-ESLRGNASGWTIKYYKGLGTSTSKEGRDYFQNLDMHKKDFVWI 636

Query: 1150 NNEDHDAIELAFSKTKIEARMDWLRAPQAGTYTDSKKKSIRYRDFINEEFKQCVVADLRR 1329
            +  D +AIELAFSK KIE R +WLR  + GT+ D K+K ++Y DF+++E  Q  +ADL+R
Sbjct: 637  DERDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQKEKLVKYSDFVHKELIQFSMADLQR 696

Query: 1330 SIPSVVDGLTRGQRKILFCAFKKPIIQEIKVAEFSHYVSEHSAYHHGEASLVGTIIGMAQ 1509
            SIPS+VDGL  GQRKILFC+FK+  I+E KVA+FS YVSEHSAYHHGE SL  TIIGMAQ
Sbjct: 697  SIPSMVDGLKPGQRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQ 756

Query: 1510 NYVGSNNINLLQPIGQYGTRYMGGKDHADDRCIFTRLSPITRYLFYEADELCL-YLNDDG 1686
            +YVGSNNIN LQP GQ+GTR +GGKDHA  R I+TRLSPITR+LF + D+  L YLN+DG
Sbjct: 757  DYVGSNNINFLQPNGQFGTRNLGGKDHASARYIYTRLSPITRFLFPKDDDRLLDYLNEDG 816

Query: 1687 QSIEP 1701
            QSIEP
Sbjct: 817  QSIEP 821


>ref|XP_024173810.1| DNA topoisomerase 2-like isoform X2 [Rosa chinensis]
          Length = 1470

 Score =  642 bits (1657), Expect = 0.0
 Identities = 351/602 (58%), Positives = 434/602 (72%), Gaps = 35/602 (5%)
 Frame = +1

Query: 1    MECLEDDTVALMKRRVVDLAGCLGNGVKVELDGKCVPVKTFEDYVKLY-------PGTST 159
            M  LEDD VALMK+RV+D+AGCLG  VKVEL+GK VPVK+F DYV L+         T  
Sbjct: 228  MTHLEDDVVALMKKRVIDMAGCLGKTVKVELNGKRVPVKSFLDYVDLFLQSAGKSKDTKL 287

Query: 160  TRIYEKVHDRWDICVCLSDGKFKQVSFLNYVATMKGGSQVDYITNQITGHLERVVN---- 327
             R+ EKV+DRW+ICV LSDG+F+QVSF+N +AT+KGG+ VDY+TNQIT H+  VVN    
Sbjct: 288  PRMTEKVNDRWEICVSLSDGQFQQVSFVNSIATIKGGTHVDYVTNQITAHVMNVVNKKNK 347

Query: 328  ---FEPDNIKSYLWVFVNA------FDSQTKENLTTTDKGIYGSACELTHEFLKRIAKPY 480
                +  N+K+YLWVFVNA      FDSQTKE LT      +GS CEL  EFLK++AK  
Sbjct: 348  NANLKAHNVKNYLWVFVNALIDNPAFDSQTKETLTIRPSS-FGSKCELPQEFLKKVAKSG 406

Query: 481  LRKRLSLLKDNPDNQYEGLKKTAGKRKGKL-NIALLEDANMAATNKSRECTLILTQGDSA 657
            + +  SLL      Q + LKKT G +  +L NI  LEDAN+A    S +CTLILT+GDSA
Sbjct: 407  VVE--SLLSWASFKQNKDLKKTDGTKTERLHNINKLEDANLAGGRNSEKCTLILTEGDSA 464

Query: 658  KAFAMSGLAVLGQDYYGVLPLKDKLLNVREASHQKLQENTEIQNIKEILGLQDGKVYENV 837
            KA AM+GLAV+G+D+YGV PL+ KLLNVREAS  ++++N EI+NIK+ILGLQ  K Y N+
Sbjct: 465  KALAMAGLAVVGRDHYGVFPLRGKLLNVREASATQVRDNEEIKNIKKILGLQQDKQYTNI 524

Query: 838  EELRYGHLMIMADEDHDGSRIKGLLINFFHTFWPSLLKVPHFMRAFIKDVKW-------- 993
            + LRYGHLMIM D+DHDGS IKGLLINF H+FWPSLLKVP F+  FI  +          
Sbjct: 525  KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATQKNGKE 584

Query: 994  --FYIMHEYVTSKVESLGNEATKYIIKYFKGLGTT--EDEAQYF-GFDHHIQDFVWANNE 1158
              FY M EY   + ESL   A+ + IKY+KGLGT+  ++   YF     H +DFVW + +
Sbjct: 585  LAFYSMPEYEAWR-ESLRGNASGWTIKYYKGLGTSTSKEGRDYFQNLGMHKKDFVWIDEQ 643

Query: 1159 DHDAIELAFSKTKIEARMDWLRAPQAGTYTDSKKKSIRYRDFINEEFKQCVVADLRRSIP 1338
            D +AIELAFSK KIE R +WLR  + GT+ D K K ++Y DF+++E  Q  +ADL+RSIP
Sbjct: 644  DGEAIELAFSKKKIEERKNWLRQFEPGTHLDQKAKLVKYSDFVHKELIQFSMADLQRSIP 703

Query: 1339 SVVDGLTRGQRKILFCAFKKPIIQEIKVAEFSHYVSEHSAYHHGEASLVGTIIGMAQNYV 1518
            S+VDGL  GQRKILFC+FK+  I+E KVA+FS YVSEHSAYHHGE SL  TIIGMAQ+YV
Sbjct: 704  SMVDGLKPGQRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYV 763

Query: 1519 GSNNINLLQPIGQYGTRYMGGKDHADDRCIFTRLSPITRYLFYEADELCL-YLNDDGQSI 1695
            GSNNINLLQP GQ+GTR +GGKDHA  R I+T+LSPITR+LF + D+  L YLN+DGQSI
Sbjct: 764  GSNNINLLQPNGQFGTRNLGGKDHASARYIYTKLSPITRFLFPKDDDRLLDYLNEDGQSI 823

Query: 1696 EP 1701
            EP
Sbjct: 824  EP 825


>ref|XP_024173808.1| DNA topoisomerase 2-like isoform X1 [Rosa chinensis]
 gb|PRQ54739.1| putative DNA topoisomerase (ATP-hydrolyzing) [Rosa chinensis]
          Length = 1471

 Score =  642 bits (1657), Expect = 0.0
 Identities = 351/602 (58%), Positives = 434/602 (72%), Gaps = 35/602 (5%)
 Frame = +1

Query: 1    MECLEDDTVALMKRRVVDLAGCLGNGVKVELDGKCVPVKTFEDYVKLY-------PGTST 159
            M  LEDD VALMK+RV+D+AGCLG  VKVEL+GK VPVK+F DYV L+         T  
Sbjct: 228  MTHLEDDVVALMKKRVIDMAGCLGKTVKVELNGKRVPVKSFLDYVDLFLQSAGKSKDTKL 287

Query: 160  TRIYEKVHDRWDICVCLSDGKFKQVSFLNYVATMKGGSQVDYITNQITGHLERVVN---- 327
             R+ EKV+DRW+ICV LSDG+F+QVSF+N +AT+KGG+ VDY+TNQIT H+  VVN    
Sbjct: 288  PRMTEKVNDRWEICVSLSDGQFQQVSFVNSIATIKGGTHVDYVTNQITAHVMNVVNKKNK 347

Query: 328  ---FEPDNIKSYLWVFVNA------FDSQTKENLTTTDKGIYGSACELTHEFLKRIAKPY 480
                +  N+K+YLWVFVNA      FDSQTKE LT      +GS CEL  EFLK++AK  
Sbjct: 348  NANLKAHNVKNYLWVFVNALIDNPAFDSQTKETLTIRPSS-FGSKCELPQEFLKKVAKSG 406

Query: 481  LRKRLSLLKDNPDNQYEGLKKTAGKRKGKL-NIALLEDANMAATNKSRECTLILTQGDSA 657
            + +  SLL      Q + LKKT G +  +L NI  LEDAN+A    S +CTLILT+GDSA
Sbjct: 407  VVE--SLLSWASFKQNKDLKKTDGTKTERLHNINKLEDANLAGGRNSEKCTLILTEGDSA 464

Query: 658  KAFAMSGLAVLGQDYYGVLPLKDKLLNVREASHQKLQENTEIQNIKEILGLQDGKVYENV 837
            KA AM+GLAV+G+D+YGV PL+ KLLNVREAS  ++++N EI+NIK+ILGLQ  K Y N+
Sbjct: 465  KALAMAGLAVVGRDHYGVFPLRGKLLNVREASATQVRDNEEIKNIKKILGLQQDKQYTNI 524

Query: 838  EELRYGHLMIMADEDHDGSRIKGLLINFFHTFWPSLLKVPHFMRAFIKDVKW-------- 993
            + LRYGHLMIM D+DHDGS IKGLLINF H+FWPSLLKVP F+  FI  +          
Sbjct: 525  KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATQKNGKE 584

Query: 994  --FYIMHEYVTSKVESLGNEATKYIIKYFKGLGTT--EDEAQYF-GFDHHIQDFVWANNE 1158
              FY M EY   + ESL   A+ + IKY+KGLGT+  ++   YF     H +DFVW + +
Sbjct: 585  LAFYSMPEYEAWR-ESLRGNASGWTIKYYKGLGTSTSKEGRDYFQNLGMHKKDFVWIDEQ 643

Query: 1159 DHDAIELAFSKTKIEARMDWLRAPQAGTYTDSKKKSIRYRDFINEEFKQCVVADLRRSIP 1338
            D +AIELAFSK KIE R +WLR  + GT+ D K K ++Y DF+++E  Q  +ADL+RSIP
Sbjct: 644  DGEAIELAFSKKKIEERKNWLRQFEPGTHLDQKAKLVKYSDFVHKELIQFSMADLQRSIP 703

Query: 1339 SVVDGLTRGQRKILFCAFKKPIIQEIKVAEFSHYVSEHSAYHHGEASLVGTIIGMAQNYV 1518
            S+VDGL  GQRKILFC+FK+  I+E KVA+FS YVSEHSAYHHGE SL  TIIGMAQ+YV
Sbjct: 704  SMVDGLKPGQRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYV 763

Query: 1519 GSNNINLLQPIGQYGTRYMGGKDHADDRCIFTRLSPITRYLFYEADELCL-YLNDDGQSI 1695
            GSNNINLLQP GQ+GTR +GGKDHA  R I+T+LSPITR+LF + D+  L YLN+DGQSI
Sbjct: 764  GSNNINLLQPNGQFGTRNLGGKDHASARYIYTKLSPITRFLFPKDDDRLLDYLNEDGQSI 823

Query: 1696 EP 1701
            EP
Sbjct: 824  EP 825


>gb|OWM78385.1| hypothetical protein CDL15_Pgr016109 [Punica granatum]
 gb|PKI31894.1| hypothetical protein CRG98_047704 [Punica granatum]
          Length = 1473

 Score =  642 bits (1655), Expect = 0.0
 Identities = 350/603 (58%), Positives = 437/603 (72%), Gaps = 36/603 (5%)
 Frame = +1

Query: 1    MECLEDDTVALMKRRVVDLAGCLGNGVKVELDGKCVPVKTFEDYVKLY--------PGTS 156
            M  LEDD VALMK+RVVDLAGCLG  VKVEL+GK VPVKTF +YV LY        P +S
Sbjct: 227  MTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGKRVPVKTFGEYVGLYLASASKNRPESS 286

Query: 157  TTRIYEKVHDRWDICVCLSDGKFKQVSFLNYVATMKGGSQVDYITNQITGHLERVVN--- 327
              RI E V+DRW++CV LS+G+F+QVSF+N +AT+KGG+ VDY+TNQI  H+  VVN   
Sbjct: 287  LPRIEEAVNDRWEVCVSLSEGQFQQVSFVNSIATIKGGTHVDYVTNQIANHVMSVVNKKN 346

Query: 328  ----FEPDNIKSYLWVFVNA------FDSQTKENLTTTDKGIYGSACELTHEFLKRIAKP 477
                 +  N+K++LWVFVNA      FDSQTKE LT      +GS CEL+ +FL+++AK 
Sbjct: 347  KNANLKAHNVKNHLWVFVNALIDNPAFDSQTKETLTLRQSS-FGSKCELSDKFLQKVAKS 405

Query: 478  YLRKRLSLLKDNPDNQYEGLKKTAGKRKGKLN-IALLEDANMAATNKSRECTLILTQGDS 654
             + +  +LL        + LKKT G +K  L  I  LEDAN A    S +CTLILT+GDS
Sbjct: 406  GIVE--TLLSWATFKLSKDLKKTDGSKKENLRGIPKLEDANDAGGRNSDKCTLILTEGDS 463

Query: 655  AKAFAMSGLAVLGQDYYGVLPLKDKLLNVREASHQKLQENTEIQNIKEILGLQDGKVYEN 834
            AKA AM+GL+V+G+D+YGV PL+ KLLNVREASH ++ +N EIQ+IK+ILGLQ  K Y++
Sbjct: 464  AKALAMAGLSVVGRDHYGVFPLRGKLLNVREASHSQIMDNKEIQHIKQILGLQQNKDYDS 523

Query: 835  VEELRYGHLMIMADEDHDGSRIKGLLINFFHTFWPSLLKVPHFMRAFIKDVK-------- 990
            V+ LRYGHLMIM D+DHDGS IKGLLINF H+FWPSLLKVP FM  FI  +         
Sbjct: 524  VKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFMVEFITPIVKATHKNGR 583

Query: 991  --WFYIMHEYVTSKVESLGNEATKYIIKYFKGLGTT--EDEAQYF-GFDHHIQDFVWANN 1155
               FY M EY + K ESL   A+ + IKY+KGLGT+  ++  QYF   + H +DF+WA+ 
Sbjct: 584  ELCFYTMPEYESWK-ESLSGNASGWSIKYYKGLGTSTSKEGKQYFQALNKHKKDFIWADE 642

Query: 1156 EDHDAIELAFSKTKIEARMDWLRAPQAGTYTDSKKKSIRYRDFINEEFKQCVVADLRRSI 1335
            +D +AIELAFSK KIEAR +WLR  + GT+ D K+K I+Y DF+N+E     +ADL+RSI
Sbjct: 643  KDGEAIELAFSKKKIEARKNWLRQFEPGTFLDQKEKLIKYSDFVNKELILFSMADLQRSI 702

Query: 1336 PSVVDGLTRGQRKILFCAFKKPIIQEIKVAEFSHYVSEHSAYHHGEASLVGTIIGMAQNY 1515
            PS++DGL  GQRKILFC+FK+  ++E KVA+FS YVSEHSAYHHGE SL GTIIGMAQ++
Sbjct: 703  PSMLDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLAGTIIGMAQDF 762

Query: 1516 VGSNNINLLQPIGQYGTRYMGGKDHADDRCIFTRLSPITRYLFYEADELCL-YLNDDGQS 1692
            VGSNNINLL P GQ+GTR MGGKDHA  R I+TRLSPITR+LF + D+  L YLN+DG S
Sbjct: 763  VGSNNINLLVPSGQFGTRNMGGKDHASPRYIYTRLSPITRFLFPKDDDNLLDYLNEDGVS 822

Query: 1693 IEP 1701
            IEP
Sbjct: 823  IEP 825


>ref|XP_010023597.1| PREDICTED: DNA topoisomerase 2 [Eucalyptus grandis]
 gb|KCW59909.1| hypothetical protein EUGRSUZ_H02633 [Eucalyptus grandis]
          Length = 1438

 Score =  640 bits (1652), Expect = 0.0
 Identities = 352/603 (58%), Positives = 433/603 (71%), Gaps = 36/603 (5%)
 Frame = +1

Query: 1    MECLEDDTVALMKRRVVDLAGCLGNGVKVELDGKCVPVKTFEDYVKLY--------PGTS 156
            M  LEDD VALMK+RV+D+AGCLG  VKVEL+GK VPVKTF +YV LY        P  S
Sbjct: 233  MTHLEDDVVALMKKRVIDMAGCLGKTVKVELNGKRVPVKTFAEYVGLYLKSASKNRPEAS 292

Query: 157  TTRIYEKVHDRWDICVCLSDGKFKQVSFLNYVATMKGGSQVDYITNQITGHLERVVNFEP 336
              RI E V++RW++CV LS+G+F+QVSF+N +AT+KGG+ VDY+TNQI  H+  VVN + 
Sbjct: 293  LPRIEETVNERWEVCVSLSEGQFQQVSFVNGIATIKGGTHVDYVTNQIANHVMSVVNKKN 352

Query: 337  DN-------IKSYLWVFVNA------FDSQTKENLTTTDKGIYGSACELTHEFLKRIAKP 477
             N       +KS+LWVFVNA      FDSQTKE LT      +GS CEL+ +FL+++AK 
Sbjct: 353  KNANLKAHHVKSHLWVFVNALIDNPAFDSQTKETLTLRQSS-FGSKCELSDKFLQKVAKS 411

Query: 478  YLRKRLSLLKDNPDNQYEGLKKTAG-KRKGKLNIALLEDANMAATNKSRECTLILTQGDS 654
             + +  SLL      Q + LKKT G KR+    I  LEDAN A    S +CTLILT+GDS
Sbjct: 412  GIVE--SLLSWANFKQSKDLKKTDGSKRENLRGIPKLEDANDAGGRNSDKCTLILTEGDS 469

Query: 655  AKAFAMSGLAVLGQDYYGVLPLKDKLLNVREASHQKLQENTEIQNIKEILGLQDGKVYEN 834
            AKA AM+GL+V+G+D YGV PL+ KLLNVREASH ++ EN EIQ +K+ILGLQ  K Y++
Sbjct: 470  AKALAMAGLSVVGRDRYGVFPLRGKLLNVREASHSQIMENKEIQYMKQILGLQQNKDYDS 529

Query: 835  VEELRYGHLMIMADEDHDGSRIKGLLINFFHTFWPSLLKVPHFMRAFIKDVKW------- 993
            V+ LRYGHLMIM D+DHDGS IKGLLINF H+FWPSLLKVP F+  FI  +         
Sbjct: 530  VKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHKNGR 589

Query: 994  ---FYIMHEYVTSKVESLGNEATKYIIKYFKGLGTT--EDEAQYF-GFDHHIQDFVWANN 1155
               FY M EY + K ESLG  A+ + IKY+KGLGT+  ++  QYF     H +DFVW ++
Sbjct: 590  ELSFYTMPEYESWK-ESLGGNASGWSIKYYKGLGTSTSKEGKQYFQNLQLHKKDFVWVDD 648

Query: 1156 EDHDAIELAFSKTKIEARMDWLRAPQAGTYTDSKKKSIRYRDFINEEFKQCVVADLRRSI 1335
            +D DAIELAFSK KIEAR  WLR  + GTY D K+K I+Y DF+N+E     +ADL+RSI
Sbjct: 649  QDGDAIELAFSKKKIEARKTWLRQYEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSI 708

Query: 1336 PSVVDGLTRGQRKILFCAFKKPIIQEIKVAEFSHYVSEHSAYHHGEASLVGTIIGMAQNY 1515
            PS+VDGL  GQRKILFC+FK+  I+E KVA+FS YVSEHSAYHHGE SL  TIIGMAQ++
Sbjct: 709  PSMVDGLKPGQRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDF 768

Query: 1516 VGSNNINLLQPIGQYGTRYMGGKDHADDRCIFTRLSPITRYLF-YEADELCLYLNDDGQS 1692
            VGSNNINLL P GQ+GTR +GGKDHA  R I+T+LSPITR+LF  + D L  YLN+DGQS
Sbjct: 769  VGSNNINLLMPNGQFGTRNLGGKDHASSRYIYTKLSPITRFLFPKDDDNLLNYLNEDGQS 828

Query: 1693 IEP 1701
            IEP
Sbjct: 829  IEP 831