BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Chrysanthemum22_contig00020140
         (2536 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_023771449.1| DNA topoisomerase 1 alpha-like [Lactuca sativa]  1248   0.0  
ref|XP_022017085.1| DNA topoisomerase 1 beta-like [Helianthus an...  1221   0.0  
gb|KVI01089.1| DNA breaking-rejoining enzyme, catalytic core [Cy...  1173   0.0  
ref|XP_023748033.1| DNA topoisomerase 1 alpha-like [Lactuca sati...  1155   0.0  
ref|XP_022041894.1| DNA topoisomerase 1 alpha-like [Helianthus a...  1154   0.0  
ref|XP_011093631.1| DNA topoisomerase 1 [Sesamum indicum] >gi|11...  1091   0.0  
dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]              1075   0.0  
ref|XP_017241904.1| PREDICTED: DNA topoisomerase 1-like [Daucus ...  1075   0.0  
ref|XP_022846035.1| DNA topoisomerase 1 beta-like [Olea europaea...  1075   0.0  
dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]      1071   0.0  
dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]                1068   0.0  
emb|CDP13767.1| unnamed protein product [Coffea canephora]           1066   0.0  
gb|KZV21640.1| DNA topoisomerase 1-like [Dorcoceras hygrometricum]   1059   0.0  
gb|PIN13662.1| DNA topoisomerase I [Handroanthus impetiginosus]      1055   0.0  
dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]               1052   0.0  
dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. g...  1044   0.0  
dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]            1042   0.0  
ref|XP_023553297.1| DNA topoisomerase 1 beta-like [Cucurbita pep...  1039   0.0  
ref|XP_009619726.2| PREDICTED: DNA topoisomerase 1-like [Nicotia...  1038   0.0  
dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]                 1036   0.0  

>ref|XP_023771449.1| DNA topoisomerase 1 alpha-like [Lactuca sativa]
          Length = 828

 Score = 1248 bits (3229), Expect = 0.0
 Identities = 646/835 (77%), Positives = 685/835 (82%), Gaps = 26/835 (3%)
 Frame = -3

Query: 2492 MNYSSDEDDKPLVFKRSSTADKSKHSSQQKAAPTVKQEXXXXXXXXXXXS---------- 2343
            MNYSSDEDDKPLVFKRSS +D+ KHSSQQK     KQE           +          
Sbjct: 1    MNYSSDEDDKPLVFKRSSNSDRLKHSSQQKPTSISKQENPVAKPVAKPVAKPLARPIVKP 60

Query: 2342 ------DTEDSEDDKPLSSRILTAP-KGNSNHTKT----GPPTSSSQRPKPPVKAKVKDE 2196
                  D+EDSEDDKPLSSRI   P K NSNH K      P  SSSQ P+P    +VK E
Sbjct: 61   PPKQKSDSEDSEDDKPLSSRISVVPNKPNSNHVKITPNPNPNPSSSQHPRP----QVKHE 116

Query: 2195 DSDDEKPLSLKITSKSSAGASINKHDDSDDDKPLSSRVKQNGSASRDNQIKKPSVGVNKR 2016
            DS DEKPLS K T K S G  I KHDDSDDDKPLSSRV QNGSASRDNQIKKP++G+NKR
Sbjct: 117  DSKDEKPLSSKFTPKPSIGPFIRKHDDSDDDKPLSSRVNQNGSASRDNQIKKPNLGLNKR 176

Query: 2015 PPNEERSSGQSLVKKPKLSDS--STPINRKPAPAKPEADT--DDENDHVPISQRIKNQTP 1848
            PPNEERSS Q LVKKPKLSDS   TPI RKP   KPEA++  DDENDHVPISQRIKNQ+P
Sbjct: 177  PPNEERSSSQPLVKKPKLSDSYSPTPIIRKPE-VKPEAESSDDDENDHVPISQRIKNQSP 235

Query: 1847 XXXXXXXXXXXXXXXXXSFLKKTNQKSKRVEKNSKYSKPSKVPPGSGEGQKWTSLAHNGV 1668
                             S   KT +KSK+VEK SKYSKPSKVPPGSGEGQKWTSL HNGV
Sbjct: 236  SSSKSASVKKVMKVTSSS--SKTFKKSKKVEKKSKYSKPSKVPPGSGEGQKWTSLVHNGV 293

Query: 1667 IFPPPYQPHGVKILYKGKPVELTPEQEEVATMFAVMLDTDYMTKPVFKENFWNDWRKILG 1488
            IFPPPY+PHGVKILYKGKPV+LTPEQEEVATMFAVMLDTDYMTKPVFK+NFWNDWRKILG
Sbjct: 294  IFPPPYKPHGVKILYKGKPVDLTPEQEEVATMFAVMLDTDYMTKPVFKQNFWNDWRKILG 353

Query: 1487 RNHTIQNLEDCDFKPIYDWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAVVDGVKEK 1308
            RNHTIQ+L+DCDFKPIYDWH                           KYMWA+VDGVKEK
Sbjct: 354  RNHTIQSLDDCDFKPIYDWHQREKEKKKQMTTEEKKAIKEEKMKLEEKYMWAIVDGVKEK 413

Query: 1307 VGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDITINIGKGEPIPECPIPGQSWKEVRHDN 1128
            VGNFRVEPPGLFRGRGEHPKMGKLK RI+PSDITINIGKG PIPECPIPG+SWKE+RHDN
Sbjct: 414  VGNFRVEPPGLFRGRGEHPKMGKLKSRIRPSDITINIGKGAPIPECPIPGESWKEIRHDN 473

Query: 1127 TVTWLAYWNDPINGKDFKYVFLAASSALKGQSDKEKYEKARSLKKHIEGIRKAYTKDFGN 948
            TVTWLAYWND INGKDFKYVFLAASSALKGQSDKEKYEKAR LK +I GIR+AYTKDF N
Sbjct: 474  TVTWLAYWNDAINGKDFKYVFLAASSALKGQSDKEKYEKARLLKGYIGGIRQAYTKDFTN 533

Query: 947  KDLTKRQVAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENCEPVPPNILKFDFLGKD 768
            KDLTKRQVAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVEN EP PPNILKFDFLGKD
Sbjct: 534  KDLTKRQVAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPQPPNILKFDFLGKD 593

Query: 767  SIRYQNEVEVELPVFKAIQQFRTGKKGNDDLFDKLDTSTLNAHLKELMPGLTAKVFRTYN 588
            SIRYQNEVEVE  VFKAIQQFRTGKK N+DLFDKLDTSTLNAHLK LMPGLTAKVFRTYN
Sbjct: 594  SIRYQNEVEVEPLVFKAIQQFRTGKKSNEDLFDKLDTSTLNAHLKALMPGLTAKVFRTYN 653

Query: 587  ASITLDDMLDKGM-KGESVAENVVVYNQANKQVAIICNHQRSVSKSHGTQMTRLNEKIDE 411
            ASITLDDML+K M  G ++AENVVVYNQANK+VAIICNHQRSVSKSH  QM RLNEKI+E
Sbjct: 654  ASITLDDMLNKDMSSGGNLAENVVVYNQANKEVAIICNHQRSVSKSHSAQMMRLNEKIEE 713

Query: 410  LKALIEELETDLARAKKGKPPLKGSDGKAKRNLNPEAIRKKIDQTNAKIDKMERDKETKE 231
            LK ++EELETDL RA+KGKPPLKGSDGK KRN+NPEA++KKI QTNAKI+KMERDKETKE
Sbjct: 714  LKGVVEELETDLGRARKGKPPLKGSDGKLKRNMNPEALQKKIAQTNAKIEKMERDKETKE 773

Query: 230  DLKTIALGTSKINYLDPRITVAWCKRSEVPIEKIFNKSLLAKFAWSMDVDPSFRF 66
            DLKT+ALGTSKINYLDPRITVAWCKR EVPIEKIFNKSLLAKFAWSMDVDPSFRF
Sbjct: 774  DLKTVALGTSKINYLDPRITVAWCKRREVPIEKIFNKSLLAKFAWSMDVDPSFRF 828


>ref|XP_022017085.1| DNA topoisomerase 1 beta-like [Helianthus annuus]
 gb|OTF91899.1| putative DNA topoisomerase I [Helianthus annuus]
          Length = 847

 Score = 1221 bits (3160), Expect = 0.0
 Identities = 639/869 (73%), Positives = 681/869 (78%), Gaps = 61/869 (7%)
 Frame = -3

Query: 2489 NYSSDEDDKPLVFKRSS------------------------------------------- 2439
            +YSSDEDDKPLVFKR+S                                           
Sbjct: 4    SYSSDEDDKPLVFKRTSAADKLKHSGQLKSASSADKLKHSGQLKSASSADKLKHSGQLKS 63

Query: 2438 --TADKSKHSSQQKAAPTVKQEXXXXXXXXXXXS----DTEDSEDDKPLSSRILTAPKGN 2277
              +ADK KHS Q K+   V +E           +    DTEDSEDDKPLS+RI TAPK N
Sbjct: 64   ASSADKLKHSGQIKSTSIVNREKPSTSTKPKPPAKQESDTEDSEDDKPLSARISTAPKTN 123

Query: 2276 SNHTKTGPPTSSSQRPKPPVKAKVKDEDSDDEKPLSLKITSKSSAGASINKHDDSDDD-K 2100
            SNH KTGP  S+SQRPKP    +VK++DSDD+KPLS K TS    G S+ K DDSDDD K
Sbjct: 124  SNHAKTGP-VSASQRPKP----QVKNDDSDDKKPLSSKFTS---VGPSVKKPDDSDDDDK 175

Query: 2099 PLSSRVKQNGSASRDNQI----------KKPSVGVNKRPPNEERSSGQSLVKKPKLSDSS 1950
            PLS+RVKQNGS SRDN            KKP++G+NKRPPNEER +GQS VKKPKLSDS 
Sbjct: 176  PLSARVKQNGSTSRDNNNNNNNNNNQLNKKPNIGLNKRPPNEERLAGQSSVKKPKLSDS- 234

Query: 1949 TPINRKPAPAKPEADTDDENDHVPISQRIKNQTPXXXXXXXXXXXXXXXXXSF-LKKTNQ 1773
                            +DENDHVPISQR+K QTP                 S   KKT +
Sbjct: 235  ----------------EDENDHVPISQRMKKQTPSGSKPSSSVKQKVVKVNSSSFKKTFK 278

Query: 1772 KSKRVEKNSKYSKPSKVPPGSGEGQKWTSLAHNGVIFPPPYQPHGVKILYKGKPVELTPE 1593
            KS + EK SKYSK SKVPPGSGEGQKWT+L HNGVIFPPPY+PHG+KILYKGKPV+LTP 
Sbjct: 279  KSNKFEKKSKYSKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGIKILYKGKPVDLTPA 338

Query: 1592 QEEVATMFAVMLDTDYMTKPVFKENFWNDWRKILGRNHTIQNLEDCDFKPIYDWHXXXXX 1413
            QEEVATMFAVMLDTDYMTKPVFKENFWNDWRKILGRNHTIQNLEDCDFKPIYDWH     
Sbjct: 339  QEEVATMFAVMLDTDYMTKPVFKENFWNDWRKILGRNHTIQNLEDCDFKPIYDWHQREKE 398

Query: 1412 XXXXXXXXXXXXXXXXXXXXXXKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK 1233
                                  KYMWA+VDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK
Sbjct: 399  KKKQMSTEEKKAIKEEKMKLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK 458

Query: 1232 KRIQPSDITINIGKGEPIPECPIPGQSWKEVRHDNTVTWLAYWNDPINGKDFKYVFLAAS 1053
            KRI+PSDITINIGKG PIPECPIPG+SWKEVRHDNTVTWLAYWNDPINGKDFKYVFLAAS
Sbjct: 459  KRIRPSDITINIGKGAPIPECPIPGESWKEVRHDNTVTWLAYWNDPINGKDFKYVFLAAS 518

Query: 1052 SALKGQSDKEKYEKARSLKKHIEGIRKAYTKDFGNKDLTKRQVAVATYLIDKLALRAGNE 873
            SALKGQSDKEKYEKARSLKK+IEGIRKAYTKDF NKD+TKRQVAVATYLIDKLALRAGNE
Sbjct: 519  SALKGQSDKEKYEKARSLKKYIEGIRKAYTKDFINKDVTKRQVAVATYLIDKLALRAGNE 578

Query: 872  KDDDEADTVGCCTLKVENCEPVPPNILKFDFLGKDSIRYQNEVEVELPVFKAIQQFRTGK 693
            KDDDEADTVGCCTLKVEN EP PPNILKFDFLGKDSIRYQNEVEVELPVFKAIQQFR+GK
Sbjct: 579  KDDDEADTVGCCTLKVENVEPKPPNILKFDFLGKDSIRYQNEVEVELPVFKAIQQFRSGK 638

Query: 692  KGNDDLFDKLDTSTLNAHLKELMPGLTAKVFRTYNASITLDDMLDKGMKGESVAENVVVY 513
            KGNDDLFDKLDTSTLNAHLKELMPGLTAKVFRTYNASITLDDML KG  G +VAENVVVY
Sbjct: 639  KGNDDLFDKLDTSTLNAHLKELMPGLTAKVFRTYNASITLDDMLSKGATGGNVAENVVVY 698

Query: 512  NQANKQVAIICNHQRSVSKSHGTQMTRLNEKIDELKALIEELETDLARAKKGKPPLKGSD 333
            NQANK+VAIICNHQRSVSKSH  QM RLNEKI+ELK ++EELETDLARAKKGKPPLKGSD
Sbjct: 699  NQANKEVAIICNHQRSVSKSHTAQMMRLNEKIEELKGVLEELETDLARAKKGKPPLKGSD 758

Query: 332  GKAKRNLNPEAIRKKIDQTNAKIDKMERDKETKEDLKTIALGTSKINYLDPRITVAWCKR 153
            GK KRN+NPEA++KKIDQT AKI+KMERDKETKEDLKT+ALGTSKINYLDPRITVAWCKR
Sbjct: 759  GKIKRNMNPEALQKKIDQTYAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKR 818

Query: 152  SEVPIEKIFNKSLLAKFAWSMDVDPSFRF 66
             EVPIEKIFNKSLLAKFAWSMDVDPSFRF
Sbjct: 819  QEVPIEKIFNKSLLAKFAWSMDVDPSFRF 847


>gb|KVI01089.1| DNA breaking-rejoining enzyme, catalytic core [Cynara cardunculus
            var. scolymus]
          Length = 778

 Score = 1173 bits (3034), Expect = 0.0
 Identities = 606/810 (74%), Positives = 653/810 (80%), Gaps = 1/810 (0%)
 Frame = -3

Query: 2492 MNYSSDEDDKPLVFKRSSTADKSKHSSQQKAAPTVKQEXXXXXXXXXXXSDTEDSEDDKP 2313
            MNYSSDEDDKPLVF+RSS ADK K SSQ    P+ K              D  DSEDDKP
Sbjct: 1    MNYSSDEDDKPLVFRRSSKADKVKCSSQS-LRPSPKPSN-----------DLTDSEDDKP 48

Query: 2312 LSSRILTAPKGNSNHTKTGPPTSSSQRPKPPVKAKVKDEDSDDEKPLSLKITSKSSAGAS 2133
            LS R+ T  KGN+NH K G   + S  PKP    +VKDEDSDDEKPLS K  SK +  +S
Sbjct: 49   LSFRLSTVSKGNTNHAKKGSCMNVSPLPKP----QVKDEDSDDEKPLSSKYISKPNVVSS 104

Query: 2132 INKHDDSDDDKPLSSRVKQNGSASRDNQIKKPSVGVNKRPPNEERSSGQSLVKKPKLSDS 1953
            I+KH  S++DK L+S+V QNGSASRDNQ +  S G  KRP +EERSS QSL KKPKLS+S
Sbjct: 105  ISKHSGSNNDKTLTSKVHQNGSASRDNQSR--STGSIKRPLDEERSSSQSLAKKPKLSES 162

Query: 1952 STPINRKPAPAKPEADTDD-ENDHVPISQRIKNQTPXXXXXXXXXXXXXXXXXSFLKKTN 1776
            STPINRK  P K E ++DD E D VPISQRIKN  P                 S LK+TN
Sbjct: 163  STPINRKQVPLKAETESDDDEEDDVPISQRIKNHAPSGSKSSSVKHKVTKKNSS-LKETN 221

Query: 1775 QKSKRVEKNSKYSKPSKVPPGSGEGQKWTSLAHNGVIFPPPYQPHGVKILYKGKPVELTP 1596
            +KSK+V KNSKYSKPSKVPPGSGEGQKWTSL H+GVIFPP Y+PHGVKILYKGKPV+LTP
Sbjct: 222  KKSKKVVKNSKYSKPSKVPPGSGEGQKWTSLVHSGVIFPPAYKPHGVKILYKGKPVDLTP 281

Query: 1595 EQEEVATMFAVMLDTDYMTKPVFKENFWNDWRKILGRNHTIQNLEDCDFKPIYDWHXXXX 1416
            EQEEVATMFAVMLDTDYMTKP FKENFW+DWRKILGRNHTIQNL+DCDFKPIY+WH    
Sbjct: 282  EQEEVATMFAVMLDTDYMTKPKFKENFWDDWRKILGRNHTIQNLDDCDFKPIYEWHQTEK 341

Query: 1415 XXXXXXXXXXXXXXXXXXXXXXXKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL 1236
                                   KYMWA+VDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL
Sbjct: 342  EKKKQMSTEEKKALKEEKMKLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL 401

Query: 1235 KKRIQPSDITINIGKGEPIPECPIPGQSWKEVRHDNTVTWLAYWNDPINGKDFKYVFLAA 1056
            KKRI PSDITINIGK  PIPECPIPG+SWKE+RHDNTVTWLAYWNDPIN K+FKYVFLAA
Sbjct: 402  KKRIHPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINSKEFKYVFLAA 461

Query: 1055 SSALKGQSDKEKYEKARSLKKHIEGIRKAYTKDFGNKDLTKRQVAVATYLIDKLALRAGN 876
            SS+LKGQSDKEKYEKAR LK +I+GIR AYT+DFGNKDLTKRQVAVATYLIDKLALRAGN
Sbjct: 462  SSSLKGQSDKEKYEKARMLKGYIQGIRNAYTRDFGNKDLTKRQVAVATYLIDKLALRAGN 521

Query: 875  EKDDDEADTVGCCTLKVENCEPVPPNILKFDFLGKDSIRYQNEVEVELPVFKAIQQFRTG 696
            EKDDDEADTVGCCTLKVEN EP PPNILKFDFLGKDSIRYQNEVEVELPVFKAIQQFRTG
Sbjct: 522  EKDDDEADTVGCCTLKVENVEPKPPNILKFDFLGKDSIRYQNEVEVELPVFKAIQQFRTG 581

Query: 695  KKGNDDLFDKLDTSTLNAHLKELMPGLTAKVFRTYNASITLDDMLDKGMKGESVAENVVV 516
            K+G DDLFDKLDTS LNAHLKELMPGLTAKVFRTYNASITLDDML +  KG  VA+N+VV
Sbjct: 582  KQGTDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAQNLVV 641

Query: 515  YNQANKQVAIICNHQRSVSKSHGTQMTRLNEKIDELKALIEELETDLARAKKGKPPLKGS 336
            Y  ANK+VAIICNHQR+VSKSH  QMTRLNEKIDELK +I+ELETDL RAKKGKPPLK S
Sbjct: 642  YQHANKEVAIICNHQRTVSKSHSAQMTRLNEKIDELKGVIKELETDLVRAKKGKPPLKNS 701

Query: 335  DGKAKRNLNPEAIRKKIDQTNAKIDKMERDKETKEDLKTIALGTSKINYLDPRITVAWCK 156
            DGK KRNLNPEA+ KKI QTNAKI+KMERDKETKEDLKT+ALGTSKINYLDPRITV    
Sbjct: 702  DGKPKRNLNPEALAKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITV---- 757

Query: 155  RSEVPIEKIFNKSLLAKFAWSMDVDPSFRF 66
                     FNKSLLAKFAWSMDVDP+FRF
Sbjct: 758  ---------FNKSLLAKFAWSMDVDPNFRF 778


>ref|XP_023748033.1| DNA topoisomerase 1 alpha-like [Lactuca sativa]
 gb|PLY62974.1| hypothetical protein LSAT_1X128740 [Lactuca sativa]
          Length = 788

 Score = 1155 bits (2987), Expect = 0.0
 Identities = 598/816 (73%), Positives = 654/816 (80%), Gaps = 7/816 (0%)
 Frame = -3

Query: 2492 MNYSSDEDDKPLVFKRSSTADKSKHSSQQKAAPTVKQEXXXXXXXXXXXSDTEDSEDDKP 2313
            M+YSSD DDKPL+F+R++  D  K SS Q + P+ K              D  DSEDDKP
Sbjct: 1    MSYSSD-DDKPLIFRRNARPDTVK-SSSQPSKPSPKPSN-----------DEVDSEDDKP 47

Query: 2312 LSSRILTAPKGNSNHTKTGPPTSSSQRPKPPVKAKVKDEDSDDEKPLSLKITSKSSAGAS 2133
            LS RI T  KG++NH K GP TS S  PKP     VKDEDSDDEKPLS K  SKS  G+S
Sbjct: 48   LSFRISTVSKGDTNHAKKGPGTSVSPLPKP----SVKDEDSDDEKPLSSKYNSKSKVGSS 103

Query: 2132 INKHDDSDDDKPLSSRVKQNGSASRDNQIKKPSVGVNKRPPNEERSSGQSLVKKPKLSDS 1953
             N H      KP+  +V QNGSAS+DN   K ++G+NKRPP+EERS+    VKKPKLSDS
Sbjct: 104  -NNH------KPVVPKVHQNGSASKDNTQLK-NIGLNKRPPDEERSAS---VKKPKLSDS 152

Query: 1952 STPINRKPAPAKPE--ADTDDENDHVPISQRIKNQTPXXXXXXXXXXXXXXXXXSF-LKK 1782
             TP+N KP   K E  +D DD++D VPISQRIK Q P                 S  L +
Sbjct: 153  VTPVNHKPVALKAEIKSDDDDDDDDVPISQRIKKQAPSSSNKSSSVKQKVMKKSSSSLNQ 212

Query: 1781 TNQKSKRV--EKNSKYSKPSKVPPGSGEGQKWTSLAHNGVIFPPPYQPHGVKILYKGKPV 1608
            TN+KSK++  +K SKYSKPSK+PPGSGEGQKWTSL H+GVIFPP Y+PHGVK+LYKGKPV
Sbjct: 213  TNKKSKKMMKQKQSKYSKPSKIPPGSGEGQKWTSLVHSGVIFPPEYKPHGVKMLYKGKPV 272

Query: 1607 ELTPEQEEVATMFAVMLDTDYMTKPVFKENFWNDWRKILGRNHTIQNLEDCDFKPIYDWH 1428
            +LTPEQEEVATMF+VMLDTDYM KP FKENFW DWRKILG+NHTIQNLE+CDFKPIY+WH
Sbjct: 273  DLTPEQEEVATMFSVMLDTDYMAKPQFKENFWGDWRKILGKNHTIQNLENCDFKPIYEWH 332

Query: 1427 XXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPK 1248
                                       KYMWA+VDGVKEKVGNFRVEPPGLFRGRGEHPK
Sbjct: 333  QAEKEKKKLMTTEEKKAIKEEKMKIEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPK 392

Query: 1247 MGKLKKRIQPSDITINIGKGEPIPECPIPGQSWKEVRHDNTVTWLAYWNDPINGKDFKYV 1068
            MGKLKKRI+PSDITINIGK  PIPECPIPG+ WKE+RHDNTVTWLAYWNDPIN K+FKYV
Sbjct: 393  MGKLKKRIRPSDITINIGKDAPIPECPIPGERWKEIRHDNTVTWLAYWNDPINSKEFKYV 452

Query: 1067 FLAASSALKGQSDKEKYEKARSLKKHIEGIRKAYTKDFGNKDLTKRQVAVATYLIDKLAL 888
            FLAASS+LKGQSDKEKYEKAR LK +IEGIRKAYTKDFGN D+TKRQVAVATYLIDKLAL
Sbjct: 453  FLAASSSLKGQSDKEKYEKARKLKGYIEGIRKAYTKDFGNSDVTKRQVAVATYLIDKLAL 512

Query: 887  RAGNEKDDDEADTVGCCTLKVENCEPVPPNILKFDFLGKDSIRYQNEVEVELPVFKAIQQ 708
            RAGNEKDDDEADTVGCCTLKVEN EP PPNILKFDFLGKDSIRYQNEVEVELPVFKAIQQ
Sbjct: 513  RAGNEKDDDEADTVGCCTLKVENVEPEPPNILKFDFLGKDSIRYQNEVEVELPVFKAIQQ 572

Query: 707  FRTGKKGNDDLFDKLDTSTLNAHLKELMPGLTAKVFRTYNASITLDDMLDKGMKGESVAE 528
            FRTGK GNDDLFDKLDTS LNAHLKELMPGLTAKVFRTYNASITLDDML +  KG  VA+
Sbjct: 573  FRTGKAGNDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLTRETKGGDVAQ 632

Query: 527  NVVVYNQANKQVAIICNHQRSVSKSHGTQMTRLNEKIDELKALIEELETDLARAKKGKPP 348
            N+VVY  ANK+VAIICNHQR+VSKSH  QMTRLNEKIDELK +I+ELE+DLARAKKGKPP
Sbjct: 633  NLVVYQHANKEVAIICNHQRTVSKSHSAQMTRLNEKIDELKGVIKELESDLARAKKGKPP 692

Query: 347  --LKGSDGKAKRNLNPEAIRKKIDQTNAKIDKMERDKETKEDLKTIALGTSKINYLDPRI 174
                G DGK KRNLNPEA+ KKI QTNAKI+KMERDKETKEDLKT+ALGTSKINYLDPRI
Sbjct: 693  SNKNGPDGKPKRNLNPEALEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRI 752

Query: 173  TVAWCKRSEVPIEKIFNKSLLAKFAWSMDVDPSFRF 66
            TVAWCKR EVPIEK+FNKSLLAKFAWSMDVDPSFRF
Sbjct: 753  TVAWCKRHEVPIEKLFNKSLLAKFAWSMDVDPSFRF 788


>ref|XP_022041894.1| DNA topoisomerase 1 alpha-like [Helianthus annuus]
 gb|OTG36132.1| putative DNA topoisomerase I alpha [Helianthus annuus]
          Length = 776

 Score = 1154 bits (2984), Expect = 0.0
 Identities = 595/812 (73%), Positives = 648/812 (79%), Gaps = 3/812 (0%)
 Frame = -3

Query: 2492 MNYSSDEDDKPLVFKRSSTADKSKHSSQQ-KAAPTVKQEXXXXXXXXXXXSDTEDSEDDK 2316
            M+YSSD D+KPL+F+RS   DK+K SSQ  K +P    +               DSEDDK
Sbjct: 1    MSYSSD-DEKPLIFRRSVKPDKAKGSSQPPKPSPKPSND--------------SDSEDDK 45

Query: 2315 PLSSRILTAPKG--NSNHTKTGPPTSSSQRPKPPVKAKVKDEDSDDEKPLSLKITSKSSA 2142
            PLSS+I T  KG  N+NH K G   S S  PKP    ++KDEDSDDEKPLS K  SK + 
Sbjct: 46   PLSSKISTVSKGNTNANHAKNGSHKSVSAAPKP----QIKDEDSDDEKPLSSKFISKPNV 101

Query: 2141 GASINKHDDSDDDKPLSSRVKQNGSASRDNQIKKPSVGVNKRPPNEERSSGQSLVKKPKL 1962
            G+              +++V QNGSASRDNQ K  ++ VNKRP  EE+SSGQS VKKPKL
Sbjct: 102  GS--------------ANKVHQNGSASRDNQSK--NISVNKRPLGEEKSSGQSSVKKPKL 145

Query: 1961 SDSSTPINRKPAPAKPEADTDDENDHVPISQRIKNQTPXXXXXXXXXXXXXXXXXSFLKK 1782
            SDSSTP+NRKP   K E  +DD++D +PI+QRIKNQ                   S L +
Sbjct: 146  SDSSTPVNRKPVNLKAETKSDDDDD-LPIAQRIKNQASSSSKPSSSKQKVIKKNSSSLNQ 204

Query: 1781 TNQKSKRVEKNSKYSKPSKVPPGSGEGQKWTSLAHNGVIFPPPYQPHGVKILYKGKPVEL 1602
            TN+KSK+V K SKYSKPSKVPPGSGEGQKWTSL H+GVIFPP Y+PHGVK+LYKGKPV+L
Sbjct: 205  TNKKSKKVVKESKYSKPSKVPPGSGEGQKWTSLVHSGVIFPPAYKPHGVKMLYKGKPVDL 264

Query: 1601 TPEQEEVATMFAVMLDTDYMTKPVFKENFWNDWRKILGRNHTIQNLEDCDFKPIYDWHXX 1422
            TPEQEEVATMFAVMLDTDYMTKP FKENFW DW+KILG+ H IQNL+DCDFKPIY+WH  
Sbjct: 265  TPEQEEVATMFAVMLDTDYMTKPKFKENFWEDWQKILGKKHMIQNLDDCDFKPIYEWHQS 324

Query: 1421 XXXXXXXXXXXXXXXXXXXXXXXXXKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMG 1242
                                     KYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMG
Sbjct: 325  EKEKKKQMTTEEKKALKEEKMKLEDKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMG 384

Query: 1241 KLKKRIQPSDITINIGKGEPIPECPIPGQSWKEVRHDNTVTWLAYWNDPINGKDFKYVFL 1062
            KLKKRI PSDITINIGK  PIPECPIPG SWKE+RHDNTVTWLAYW DPIN K+FKYVFL
Sbjct: 385  KLKKRIFPSDITINIGKDAPIPECPIPGDSWKEIRHDNTVTWLAYWLDPINNKEFKYVFL 444

Query: 1061 AASSALKGQSDKEKYEKARSLKKHIEGIRKAYTKDFGNKDLTKRQVAVATYLIDKLALRA 882
            AASS+LKGQSDKEKYEKAR LK +I+GIR AYTKDFGNKD+TKRQVAVATYLIDKLALRA
Sbjct: 445  AASSSLKGQSDKEKYEKARLLKGYIQGIRNAYTKDFGNKDVTKRQVAVATYLIDKLALRA 504

Query: 881  GNEKDDDEADTVGCCTLKVENCEPVPPNILKFDFLGKDSIRYQNEVEVELPVFKAIQQFR 702
            GNEKDDDEADTVGCCTLKVEN EP PPNILKFDFLGKDSIRYQNEVEVELPVFKAIQQFR
Sbjct: 505  GNEKDDDEADTVGCCTLKVENVEPSPPNILKFDFLGKDSIRYQNEVEVELPVFKAIQQFR 564

Query: 701  TGKKGNDDLFDKLDTSTLNAHLKELMPGLTAKVFRTYNASITLDDMLDKGMKGESVAENV 522
            TGK G DDLFDKLDTS LNAHLKELMPGLTAKVFRTYNASITLDDML +  KG  VAEN+
Sbjct: 565  TGKAGGDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGREVAENL 624

Query: 521  VVYNQANKQVAIICNHQRSVSKSHGTQMTRLNEKIDELKALIEELETDLARAKKGKPPLK 342
            VVY  ANK+VAIICNHQR+VSKSH  QMTRLN+KIDELK +I+ELETDLARAKKGKPPLK
Sbjct: 625  VVYQHANKEVAIICNHQRTVSKSHSAQMTRLNDKIDELKDVIKELETDLARAKKGKPPLK 684

Query: 341  GSDGKAKRNLNPEAIRKKIDQTNAKIDKMERDKETKEDLKTIALGTSKINYLDPRITVAW 162
             SDGK KRNLNPEA+ KKI QT AKI+KMERDKETKEDLKT+ALGTS+INYLDPRITVAW
Sbjct: 685  TSDGKTKRNLNPEALEKKIAQTKAKIEKMERDKETKEDLKTVALGTSRINYLDPRITVAW 744

Query: 161  CKRSEVPIEKIFNKSLLAKFAWSMDVDPSFRF 66
            CKR EVPIEKIFNKSLLAKFAWSMDVDPSFRF
Sbjct: 745  CKRHEVPIEKIFNKSLLAKFAWSMDVDPSFRF 776


>ref|XP_011093631.1| DNA topoisomerase 1 [Sesamum indicum]
 ref|XP_020553411.1| DNA topoisomerase 1 [Sesamum indicum]
          Length = 893

 Score = 1091 bits (2822), Expect = 0.0
 Identities = 560/795 (70%), Positives = 621/795 (78%), Gaps = 2/795 (0%)
 Frame = -3

Query: 2444 SSTADKSKHSSQQKAAPTVKQEXXXXXXXXXXXSDTEDSEDDKPLSSRILTA-PKGNSNH 2268
            +S  D+S     Q     +K E            D+EDSEDDKPLS+R+     K NSNH
Sbjct: 113  TSVTDESNSVKHQ-----IKDEKPSTKATGGLNEDSEDSEDDKPLSARLPAGLSKVNSNH 167

Query: 2267 TKTGPPTSSS-QRPKPPVKAKVKDEDSDDEKPLSLKITSKSSAGASINKHDDSDDDKPLS 2091
               GP   +S Q+ K P     K EDSDDE PLS K   KS+AG S N+   S + KPL 
Sbjct: 168  ANKGPNALTSVQKTKIP-----KPEDSDDEIPLSSKFQVKSNAGESTNRPSISGERKPLL 222

Query: 2090 SRVKQNGSASRDNQIKKPSVGVNKRPPNEERSSGQSLVKKPKLSDSSTPINRKPAPAKPE 1911
            ++  QNGSAS +   +KPS  + KRP +  +S+G+S +KKPKLSD+STP   K    K E
Sbjct: 223  AKYDQNGSASAE---RKPSTILKKRPADGVKSAGESYLKKPKLSDASTPNKTKETSIKDE 279

Query: 1910 ADTDDENDHVPISQRIKNQTPXXXXXXXXXXXXXXXXXSFLKKTNQKSKRVEKNSKYSKP 1731
               +D+ DHVPISQRIK QT                  S  KKT++K K+V KNSKYSK 
Sbjct: 280  MKDEDDEDHVPISQRIKQQTSSDKKSSSAKNMTKPISAS-AKKTSKKPKKVMKNSKYSKS 338

Query: 1730 SKVPPGSGEGQKWTSLAHNGVIFPPPYQPHGVKILYKGKPVELTPEQEEVATMFAVMLDT 1551
            SKVPP SGEGQKWT+L HNGVIFPPPY+PHGVK+LYKGKPV+LTPEQEEVATM+AVMLDT
Sbjct: 339  SKVPPSSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLDT 398

Query: 1550 DYMTKPVFKENFWNDWRKILGRNHTIQNLEDCDFKPIYDWHXXXXXXXXXXXXXXXXXXX 1371
            DYM KP FKENF  DWRKILG+NH IQ+LE CDF PIY+WH                   
Sbjct: 399  DYMNKPKFKENFMADWRKILGKNHVIQSLEHCDFTPIYEWHQKEKEKKKQMTAEEKKALK 458

Query: 1370 XXXXXXXXKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDITINIGK 1191
                    KYMWA+V+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI+PSDITINIGK
Sbjct: 459  EEKLKQEEKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGK 518

Query: 1190 GEPIPECPIPGQSWKEVRHDNTVTWLAYWNDPINGKDFKYVFLAASSALKGQSDKEKYEK 1011
              PIPECPIPG+SWKE+RHDNTVTWLAYWNDPIN K+FKYVFLAASS LKGQSDKEKYEK
Sbjct: 519  DAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEK 578

Query: 1010 ARSLKKHIEGIRKAYTKDFGNKDLTKRQVAVATYLIDKLALRAGNEKDDDEADTVGCCTL 831
            AR LK +I GIR AYTKDF NKD TK+Q+AVATYLIDKLALRAGNEKDDDEADTVGCCTL
Sbjct: 579  ARLLKDYIHGIRAAYTKDFTNKDPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTL 638

Query: 830  KVENCEPVPPNILKFDFLGKDSIRYQNEVEVELPVFKAIQQFRTGKKGNDDLFDKLDTST 651
            KVEN EPVPPNILKFDFLGKDSIRYQNEVEVE PVFKAIQQFR+GKKG+DD+FD+LDTS 
Sbjct: 639  KVENVEPVPPNILKFDFLGKDSIRYQNEVEVETPVFKAIQQFRSGKKGSDDMFDRLDTSK 698

Query: 650  LNAHLKELMPGLTAKVFRTYNASITLDDMLDKGMKGESVAENVVVYNQANKQVAIICNHQ 471
            LNAHLKELMPGLTAKVFRTYNASITLDD L +  KG  VAE VVVY  ANK+VAIICNHQ
Sbjct: 699  LNAHLKELMPGLTAKVFRTYNASITLDDKLSRETKGGDVAEKVVVYQHANKEVAIICNHQ 758

Query: 470  RSVSKSHGTQMTRLNEKIDELKALIEELETDLARAKKGKPPLKGSDGKAKRNLNPEAIRK 291
            R+VSKSH  QMTRLNEKI+ELK ++EEL+TDLARAKKGKPPLK +DGK KRNLNP+A+ K
Sbjct: 759  RTVSKSHSAQMTRLNEKIEELKGVLEELQTDLARAKKGKPPLKSADGKPKRNLNPDALEK 818

Query: 290  KIDQTNAKIDKMERDKETKEDLKTIALGTSKINYLDPRITVAWCKRSEVPIEKIFNKSLL 111
            KI QTNAKI+KMERDKETKEDLKT+ALGTSKINYLDPRITVAWCKR EVPIEKIFNKSLL
Sbjct: 819  KIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLL 878

Query: 110  AKFAWSMDVDPSFRF 66
            AKFAW+MDVDPSFRF
Sbjct: 879  AKFAWAMDVDPSFRF 893


>dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]
          Length = 894

 Score = 1075 bits (2780), Expect = 0.0
 Identities = 551/796 (69%), Positives = 622/796 (78%), Gaps = 3/796 (0%)
 Frame = -3

Query: 2444 SSTADKSKHSSQQKAAPTVKQEXXXXXXXXXXXSDTEDSEDDKPLSSRILTA-PKGNSNH 2268
            SS+ D+SKHSS+Q     VK+E            D   SED+KPLS+R+ T   KG+SN+
Sbjct: 105  SSSDDRSKHSSKQNTINVVKEEKELVNPAAEPYGD---SEDEKPLSARLFTGLTKGSSNN 161

Query: 2267 TKTGPPTSS-SQRPKPPVKAKVKDEDSDDEKPLSLKITSKSSAGASINKHDDSDDDKPLS 2091
               G   SS +  P P  +     +DSDDE PLS K   K++AG S  K  +SDD+K L 
Sbjct: 162  ANKGLINSSPASLPVPKPEINRYSDDSDDEIPLSSKFRLKANAGTSTVKSYESDDNKTLV 221

Query: 2090 SRVKQNGSASRDNQIKKPSVGVNKRPPNEERSSGQSLVKKPKLSDSSTPINRKPAPAKPE 1911
            S  +QNGS +R +   K S+ VNKRP  E +SS QS VKKPKLSD+STP+N K A  K E
Sbjct: 222  SNFQQNGSINRGS---KSSIKVNKRPLGEVKSSVQSSVKKPKLSDASTPVNNKQASKKAE 278

Query: 1910 ADTDD-ENDHVPISQRIKNQTPXXXXXXXXXXXXXXXXXSFLKKTNQKSKRVEKNSKYSK 1734
               DD ++DHVPISQR+K                     S +KK ++K K+V K SKYSK
Sbjct: 279  PKADDSDDDHVPISQRMKKSATSGNKSSTAKQKVTKVVSSSMKKASKKFKKVVKKSKYSK 338

Query: 1733 PSKVPPGSGEGQKWTSLAHNGVIFPPPYQPHGVKILYKGKPVELTPEQEEVATMFAVMLD 1554
             SKVPP SGEG+KW +L HNGVIFPPPY+PHGVK+LYKGKPV+LTPEQEEVATMFAVMLD
Sbjct: 339  SSKVPPSSGEGKKWNTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMLD 398

Query: 1553 TDYMTKPVFKENFWNDWRKILGRNHTIQNLEDCDFKPIYDWHXXXXXXXXXXXXXXXXXX 1374
            TDYMTK  FKENF +DWRKILG+NH IQNLEDCDF PIY+WH                  
Sbjct: 399  TDYMTKSKFKENFMDDWRKILGKNHVIQNLEDCDFTPIYEWHQREKEKKKKMTAEEKKVL 458

Query: 1373 XXXXXXXXXKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDITINIG 1194
                     KYMWA+V+GVKEKVGNFRVEPP LFRGRGEHPKMGKLKK I+PSDITINIG
Sbjct: 459  KEERLKQEEKYMWAIVNGVKEKVGNFRVEPPSLFRGRGEHPKMGKLKKCIRPSDITINIG 518

Query: 1193 KGEPIPECPIPGQSWKEVRHDNTVTWLAYWNDPINGKDFKYVFLAASSALKGQSDKEKYE 1014
            K  PIPECPIPG+SWKE+RHDNTVTWLA+WNDPI  ++FKYVFLAASS+LKGQSDKEKYE
Sbjct: 519  KDAPIPECPIPGESWKEIRHDNTVTWLAFWNDPIKPREFKYVFLAASSSLKGQSDKEKYE 578

Query: 1013 KARSLKKHIEGIRKAYTKDFGNKDLTKRQVAVATYLIDKLALRAGNEKDDDEADTVGCCT 834
            KAR LK  I+GIR AYTKDF +KD+TKRQ+AVATYLIDKLALRAGNEKDDDEADTVGCCT
Sbjct: 579  KARLLKDFIQGIRAAYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCT 638

Query: 833  LKVENCEPVPPNILKFDFLGKDSIRYQNEVEVELPVFKAIQQFRTGKKGNDDLFDKLDTS 654
            LKVEN EP PP+ILKFDFLGKDSIRYQNEVEVELPV+KAIQQFRTGK+G DDLFDKLDTS
Sbjct: 639  LKVENVEPKPPSILKFDFLGKDSIRYQNEVEVELPVYKAIQQFRTGKRGGDDLFDKLDTS 698

Query: 653  TLNAHLKELMPGLTAKVFRTYNASITLDDMLDKGMKGESVAENVVVYNQANKQVAIICNH 474
             LNAHLK LMPGLTAKVFRTYNASITLD+ML +  KG +VAE +VVY  ANK+VAIICNH
Sbjct: 699  KLNAHLKGLMPGLTAKVFRTYNASITLDEMLSRETKGGNVAEKIVVYQHANKEVAIICNH 758

Query: 473  QRSVSKSHGTQMTRLNEKIDELKALIEELETDLARAKKGKPPLKGSDGKAKRNLNPEAIR 294
            QR+VSKSH  QMTRLN KIDELK +++ L+TDLARAKKGKPPL+ +DGK KRNL PEA+ 
Sbjct: 759  QRTVSKSHPAQMTRLNGKIDELKGILDGLQTDLARAKKGKPPLEDADGKPKRNLTPEALE 818

Query: 293  KKIDQTNAKIDKMERDKETKEDLKTIALGTSKINYLDPRITVAWCKRSEVPIEKIFNKSL 114
            +KI QTNAKI+KMERDKETKE LKTIALGTSKI+YLDPRITVAWCKR EVPIEK+FNKSL
Sbjct: 819  RKIGQTNAKIEKMERDKETKEGLKTIALGTSKISYLDPRITVAWCKRHEVPIEKVFNKSL 878

Query: 113  LAKFAWSMDVDPSFRF 66
            LAKFAWSMDVDPSFRF
Sbjct: 879  LAKFAWSMDVDPSFRF 894


>ref|XP_017241904.1| PREDICTED: DNA topoisomerase 1-like [Daucus carota subsp. sativus]
 gb|KZN00059.1| hypothetical protein DCAR_008813 [Daucus carota subsp. sativus]
          Length = 895

 Score = 1075 bits (2780), Expect = 0.0
 Identities = 551/801 (68%), Positives = 631/801 (78%), Gaps = 8/801 (0%)
 Frame = -3

Query: 2444 SSTADKSKHSSQQKAAPTVKQEXXXXXXXXXXXSDTEDSEDDKPLSSRI-LTAPKGNSNH 2268
            +S AD+S+ +SQQ     VK E           S +EDS+DDKPL+SR+ +   KG+ + 
Sbjct: 104  TSGADQSRQNSQQNRTAIVKAERPSGIPKEEPDSGSEDSDDDKPLNSRLPVGGSKGSISE 163

Query: 2267 TKTGPPTSSSQRPKPPVKAK---VKDEDSDDEKPLSLKITSKSSAGASINKHDDSDDDKP 2097
                P +S      P   AK   +K+EDS+D+ PLS K   KS+AG S N +D SD+ KP
Sbjct: 164  VNRRPSSSG-----PAALAKDLGIKEEDSEDDIPLSHKFKQKSNAGESSNAYD-SDEGKP 217

Query: 2096 LSSRVKQNGSASRDNQIKKPSVGVNKRPPNEERSSGQSLVKKPKLSDSSTPINRKPAPAK 1917
             +S+ +QNG+  +DN +K PS  +NKRP  E + SGQS VKK K + +STP+N K    K
Sbjct: 218  FASKPRQNGTNVKDN-VKNPSTAINKRPSAEVKCSGQSPVKKAKHTAASTPVNGKKVTVK 276

Query: 1916 --PEADTDD-ENDHVPISQRIKNQ-TPXXXXXXXXXXXXXXXXXSFLKKTNQKSKRVEKN 1749
              P+ + DD ++D+  ISQR+K   TP                   L K N+ SK++ K+
Sbjct: 277  AEPKKEADDSDDDNATISQRVKKPATPISKASDKKKSAVSVSSS--LNKVNKNSKKITKS 334

Query: 1748 SKYSKPSKVPPGSGEGQKWTSLAHNGVIFPPPYQPHGVKILYKGKPVELTPEQEEVATMF 1569
            +++SK  KVPPGSGEGQKWT+L HNGVIFPPPY+PHGVK+LYKGKPV+LTPEQEEVATM 
Sbjct: 335  TQFSKSLKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMI 394

Query: 1568 AVMLDTDYMTKPVFKENFWNDWRKILGRNHTIQNLEDCDFKPIYDWHXXXXXXXXXXXXX 1389
            AVM DT+YMTKPVF+EN  NDW+KILGRNH I+NL+DCDF PIY+WH             
Sbjct: 395  AVMQDTEYMTKPVFRENVMNDWKKILGRNHIIKNLDDCDFTPIYEWHQTEKEKKKQMSAE 454

Query: 1388 XXXXXXXXXXXXXXKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDI 1209
                          KYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI PSDI
Sbjct: 455  EKKAVKEEKLKQEEKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRISPSDI 514

Query: 1208 TINIGKGEPIPECPIPGQSWKEVRHDNTVTWLAYWNDPINGKDFKYVFLAASSALKGQSD 1029
            TINIGK  PIPECPIPG+SWKEVRHDNTVTWLAYWNDPINGK+FKYVFLAASS+LKGQSD
Sbjct: 515  TINIGKDAPIPECPIPGESWKEVRHDNTVTWLAYWNDPINGKEFKYVFLAASSSLKGQSD 574

Query: 1028 KEKYEKARSLKKHIEGIRKAYTKDFGNKDLTKRQVAVATYLIDKLALRAGNEKDDDEADT 849
            KEKYEKAR LK +IEGIR AYTKDF +KD+TKRQ+AVATYLIDKLALRAGNEKDDDEADT
Sbjct: 575  KEKYEKARKLKGYIEGIRTAYTKDFSSKDVTKRQIAVATYLIDKLALRAGNEKDDDEADT 634

Query: 848  VGCCTLKVENCEPVPPNILKFDFLGKDSIRYQNEVEVELPVFKAIQQFRTGKKGNDDLFD 669
            VGCCTLKVEN EP PPNILK DFLGKDSIRYQNEVEVE+PVFKAIQQFR+GKKG+D+LFD
Sbjct: 635  VGCCTLKVENVEPSPPNILKLDFLGKDSIRYQNEVEVEIPVFKAIQQFRSGKKGSDNLFD 694

Query: 668  KLDTSTLNAHLKELMPGLTAKVFRTYNASITLDDMLDKGMKGESVAENVVVYNQANKQVA 489
            KLDTS LNAHLKELMPGL+AKVFRTYNASITLD+ML+K  KG  V++ V VY  ANK+VA
Sbjct: 695  KLDTSKLNAHLKELMPGLSAKVFRTYNASITLDEMLNKETKGGDVSQKVAVYQHANKEVA 754

Query: 488  IICNHQRSVSKSHGTQMTRLNEKIDELKALIEELETDLARAKKGKPPLKGSDGKAKRNLN 309
            IICNHQRSVSKSH TQM RL+EKI+ELK LIEEL+TDL+RAKKGKPPLKGSDGK KRN+N
Sbjct: 755  IICNHQRSVSKSHSTQMMRLDEKINELKNLIEELKTDLSRAKKGKPPLKGSDGKTKRNMN 814

Query: 308  PEAIRKKIDQTNAKIDKMERDKETKEDLKTIALGTSKINYLDPRITVAWCKRSEVPIEKI 129
            PEAI KKI QTN KI+KMERDKETKEDLKT+ALGTSKINYLDPRITVAWCKR EVPIEK+
Sbjct: 815  PEAIEKKIAQTNVKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKM 874

Query: 128  FNKSLLAKFAWSMDVDPSFRF 66
            FNKSLLAKFAW+MDV+PSFRF
Sbjct: 875  FNKSLLAKFAWAMDVEPSFRF 895


>ref|XP_022846035.1| DNA topoisomerase 1 beta-like [Olea europaea var. sylvestris]
          Length = 771

 Score = 1075 bits (2779), Expect = 0.0
 Identities = 544/762 (71%), Positives = 608/762 (79%), Gaps = 3/762 (0%)
 Frame = -3

Query: 2342 DTEDSEDDKPLSSRILTA-PKGNSNHTKTGPPTSS-SQRPKPPVKAKVKDEDSDDEKPLS 2169
            D+EDSEDDKPLS+R+ T+  K NSN+   G   S   Q+P  P     K EDSDDEKPLS
Sbjct: 16   DSEDSEDDKPLSARLSTSLSKNNSNNASKGSNASRLGQKPSIP-----KQEDSDDEKPLS 70

Query: 2168 LKITSKSSAGASINKHDDSDDDKPLSSRVKQNGSASRDNQIKKPSVGVNKRPPNEERSSG 1989
             K+  KS+ G+S  K  DSD+   L+++  QNGS  +D+  KKPS  ++KRP +E  S+G
Sbjct: 71   HKVQLKSNVGSSTRKSYDSDEKMHLAAKNNQNGSPLQDSGSKKPSTILSKRPASEVNSAG 130

Query: 1988 QSLVKKPKLSDSSTPINRKPAPAKPEADT-DDENDHVPISQRIKNQTPXXXXXXXXXXXX 1812
            QS +KK K+S++S  IN K A  K E    DD++DH+PISQR+K                
Sbjct: 131  QSSIKKHKISNASVLINNKQASVKAEPKVEDDDDDHIPISQRMKKPAASDKKISAIKKVT 190

Query: 1811 XXXXXSFLKKTNQKSKRVEKNSKYSKPSKVPPGSGEGQKWTSLAHNGVIFPPPYQPHGVK 1632
                 S L KTN+ SK+V K S+YSK SKVPPGSGEGQKWT+L HNGVIFPPPYQ HGVK
Sbjct: 191  KVVSSS-LNKTNKNSKKVVKKSQYSKSSKVPPGSGEGQKWTTLIHNGVIFPPPYQSHGVK 249

Query: 1631 ILYKGKPVELTPEQEEVATMFAVMLDTDYMTKPVFKENFWNDWRKILGRNHTIQNLEDCD 1452
            +LYKGKPV LTPEQEEVATMFAVMLDT+YM KP FKENF +DWRKILG+NH IQNLEDCD
Sbjct: 250  MLYKGKPVNLTPEQEEVATMFAVMLDTEYMNKPKFKENFMSDWRKILGKNHIIQNLEDCD 309

Query: 1451 FKPIYDWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAVVDGVKEKVGNFRVEPPGLF 1272
            F PIY+WH                           KYMWA+VDGVKEKVGNFRVEPPGLF
Sbjct: 310  FTPIYEWHQKEKEKKKQMTTEEKKVIKEEKMKQEEKYMWAIVDGVKEKVGNFRVEPPGLF 369

Query: 1271 RGRGEHPKMGKLKKRIQPSDITINIGKGEPIPECPIPGQSWKEVRHDNTVTWLAYWNDPI 1092
            RGRGEHPKMGKLK+RI+PSDITINIGK  PIPECPIPG+SWKE+RHDNTVTWLA+WNDPI
Sbjct: 370  RGRGEHPKMGKLKRRIRPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAFWNDPI 429

Query: 1091 NGKDFKYVFLAASSALKGQSDKEKYEKARSLKKHIEGIRKAYTKDFGNKDLTKRQVAVAT 912
            N K+ KYVFLAASS LKGQSDKEKYEK+R LK +I+GIR +YTKDF +KD TK+Q+AVAT
Sbjct: 430  NPKEIKYVFLAASSTLKGQSDKEKYEKSRLLKDYIQGIRASYTKDFASKDPTKKQIAVAT 489

Query: 911  YLIDKLALRAGNEKDDDEADTVGCCTLKVENCEPVPPNILKFDFLGKDSIRYQNEVEVEL 732
            YLIDKLALRAGNEKDDDEADTVGCCTLKVEN EP+PPNILKFDFLGKDSIRYQNEVEVE 
Sbjct: 490  YLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPMPPNILKFDFLGKDSIRYQNEVEVES 549

Query: 731  PVFKAIQQFRTGKKGNDDLFDKLDTSTLNAHLKELMPGLTAKVFRTYNASITLDDMLDKG 552
             VFKAIQQFR+GKK  DDLFDKLDTS LNAHLKELMPGLTAKVFRTYNASITLD+ML K 
Sbjct: 550  AVFKAIQQFRSGKKAADDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSKD 609

Query: 551  MKGESVAENVVVYNQANKQVAIICNHQRSVSKSHGTQMTRLNEKIDELKALIEELETDLA 372
             K   VAEN+VVY  ANK+VAIICNHQR+VSKSH  QM RLNEKI+ELK ++EEL TDL 
Sbjct: 610  TKAGDVAENIVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKVVLEELTTDLV 669

Query: 371  RAKKGKPPLKGSDGKAKRNLNPEAIRKKIDQTNAKIDKMERDKETKEDLKTIALGTSKIN 192
            RAKKGKPPLK +DGK KRNLNPEA+ KKI QTNAKI+KMERDKETKEDLKT+ALGTSKIN
Sbjct: 670  RAKKGKPPLKSADGKTKRNLNPEALEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKIN 729

Query: 191  YLDPRITVAWCKRSEVPIEKIFNKSLLAKFAWSMDVDPSFRF 66
            YLDPRITVAWCKR EVPIEKIFNKSLLAKF W+MDVDPSFRF
Sbjct: 730  YLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPSFRF 771


>dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]
          Length = 925

 Score = 1071 bits (2770), Expect = 0.0
 Identities = 551/786 (70%), Positives = 614/786 (78%), Gaps = 27/786 (3%)
 Frame = -3

Query: 2342 DTEDSEDDKPLSSRIL-TAPKGNSNHT-KTGPPTSSSQRPKPPVKAKVKDEDSDDEKPLS 2169
            ++E S+D+KPLS+R    + KG SNH  K G  + S +RP        + EDS+DEKPLS
Sbjct: 145  NSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSCSIRRP-----VIEESEDSEDEKPLS 199

Query: 2168 LKITSKSSAGASINKHDDSDDDKPLSSRVKQNGSASRDNQIKKPSVGVNKRPPNEERSSG 1989
             + TSKSS G S +K  DSD+ KPL+++V+QNGSASRD  + K +   NKRPP E +S  
Sbjct: 200  CRFTSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGPMNKSASLSNKRPPGEAKSLN 259

Query: 1988 QSLVKKPKLSDSSTPINRKPAPAKPE--ADTDDEN----------------------DHV 1881
            QS VKKPKLS   T I+ K A  KPE  A+ DD+N                      D+V
Sbjct: 260  QSSVKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQSATSKPKDDDDDNV 319

Query: 1880 PISQRIKNQTPXXXXXXXXXXXXXXXXXSFLKKTNQKSKRVEKNSKYSKPSKVPPGSGEG 1701
            PISQRIK                     S LKK N+ SK+V K + Y+K SKVPPGSGEG
Sbjct: 320  PISQRIKKSPASVSKSSVPVKKASTVVSSSLKKVNKNSKKVIKKTAYTKSSKVPPGSGEG 379

Query: 1700 QKWTSLAHNGVIFPPPYQPHGVKILYKGKPVELTPEQEEVATMFAVMLDTDYMTKPVFKE 1521
            QKWT+L HNGVIFPPPY+PHGVK+LYK +P+ LTPEQEEVATMFAVMLDTDYM KP FKE
Sbjct: 380  QKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEVATMFAVMLDTDYMNKPCFKE 439

Query: 1520 NFWNDWRKILGRNHTIQNLEDCDFKPIYDWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKY 1341
            NF++DW+KILG+NH IQNLEDCDF PIY+WH                           KY
Sbjct: 440  NFFSDWKKILGKNHMIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEKKALKEEKLQQEEKY 499

Query: 1340 MWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDITINIGKGEPIPECPIP 1161
            MWA+VDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI+P DITINIGK  PIPECPIP
Sbjct: 500  MWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDITINIGKDAPIPECPIP 559

Query: 1160 GQSWKEVRHDNTVTWLAYWNDPINGKDFKYVFLAASSALKGQSDKEKYEKARSLKKHIEG 981
            G+ WKEVR+ NTVTWLAYWNDPIN K+FKYVFLAASS LKGQSDKEKYEKAR LK +I G
Sbjct: 560  GERWKEVRNGNTVTWLAYWNDPINQKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHG 619

Query: 980  IRKAYTKDF-GNKDLTKRQVAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENCEPVP 804
            IR AYTKDF  NKD  K+Q+AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVEN EPVP
Sbjct: 620  IRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVP 679

Query: 803  PNILKFDFLGKDSIRYQNEVEVELPVFKAIQQFRTGKKGNDDLFDKLDTSTLNAHLKELM 624
            PNILKFDFLGKDSIRYQNEV+VE  VFKAIQQFR+GK+G++DLFD+LDTS LNAHLKELM
Sbjct: 680  PNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELM 739

Query: 623  PGLTAKVFRTYNASITLDDMLDKGMKGESVAENVVVYNQANKQVAIICNHQRSVSKSHGT 444
            PGLTAKVFRTYNASITLDDML K  KG  VAENVVVY  ANK+VAIICNHQR+VSKSH  
Sbjct: 740  PGLTAKVFRTYNASITLDDMLSKETKGGEVAENVVVYQHANKEVAIICNHQRTVSKSHSA 799

Query: 443  QMTRLNEKIDELKALIEELETDLARAKKGKPPLKGSDGKAKRNLNPEAIRKKIDQTNAKI 264
            QM+RLNEKIDELK  +EEL+TDL+RAKKGKPP KG+DGKAKRNLNPEA+ +KI QTNAKI
Sbjct: 800  QMSRLNEKIDELKTALEELKTDLSRAKKGKPPTKGADGKAKRNLNPEALERKITQTNAKI 859

Query: 263  DKMERDKETKEDLKTIALGTSKINYLDPRITVAWCKRSEVPIEKIFNKSLLAKFAWSMDV 84
            +KMERDKETKEDLKT+ALGTSKINYLDPRITVAWCKR EVPIEKIFNKSLLAKFAWSMDV
Sbjct: 860  EKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWSMDV 919

Query: 83   DPSFRF 66
            DPSFRF
Sbjct: 920  DPSFRF 925


>dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]
          Length = 910

 Score = 1068 bits (2762), Expect = 0.0
 Identities = 549/798 (68%), Positives = 619/798 (77%), Gaps = 5/798 (0%)
 Frame = -3

Query: 2444 SSTADKSKHSSQQKAAPTVKQEXXXXXXXXXXXS-DTEDSEDDKPLSSR-ILTAPKGNSN 2271
            +S + K K  +Q K+A  +K+E             D+EDS+D KPLS R   ++ KGN+N
Sbjct: 127  TSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSASSSKGNTN 186

Query: 2270 HTKTGPPTSSSQRPKPPVKAKVKDEDSDDEKPLSLKITSKSSAGASINKHDDSDDDKPLS 2091
                     S +  KP      ++EDSDDEKPLS +   KS  G S +K  DSDDDKPL+
Sbjct: 187  QV-------SKEGSKP------ENEDSDDEKPLSSRFPLKSGVGESTSKAYDSDDDKPLA 233

Query: 2090 SRVKQNGSASRDNQIKKPSVGVNKRPPNEERSSGQSLVKKPKLSDSSTPINRKPAPAKPE 1911
             +++ NGSA RD Q  K S   NKRPP + +SS Q  VKKPKLS  + P N+K A  KPE
Sbjct: 234  KKLQHNGSAMRDGQPNKYSNMSNKRPPGDIKSSNQLSVKKPKLSSVTAPTNKKQASVKPE 293

Query: 1910 ADT-DDENDHVPISQRIKNQTPXXXXXXXXXXXXXXXXXSFLKKTNQKSKRVEKNSKYSK 1734
                DD++DH+PISQRIK ++P                 S +KK N+KSK+V KNSKYSK
Sbjct: 294  PKAEDDDDDHLPISQRIK-KSPTSESKSSSIKKTTKVVSSSVKKVNKKSKKVMKNSKYSK 352

Query: 1733 PSKVPPGSGEGQKWTSLAHNGVIFPPPYQPHGVKILYKGKPVELTPEQEEVATMFAVMLD 1554
             SKVPP SGEG+KW  L HNGVIFPPPY+PHG+K+LYKGKPV+LTPEQEEVATMFAVMLD
Sbjct: 353  SSKVPPSSGEGKKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVATMFAVMLD 412

Query: 1553 TDYMTKPVFKENFWNDWRKILGRNHTIQNLEDCDFKPIYDWHXXXXXXXXXXXXXXXXXX 1374
            TDYM KP FKENF+ DW+KILG+NH IQNLE+CDF PIY+WH                  
Sbjct: 413  TDYMNKPRFKENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSEKEKKKQMTTEEKKAL 472

Query: 1373 XXXXXXXXXKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDITINIG 1194
                     KYMWA VDG KEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI+P DITINIG
Sbjct: 473  KEEKLKQEEKYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCDITINIG 532

Query: 1193 KGEPIPECPIPGQSWKEVRHDNTVTWLAYWNDPINGKDFKYVFLAASSALKGQSDKEKYE 1014
            K  PIPECP+PG+ WKEVRHDNTVTWLA+WNDPIN K+FKYVFLAASS LKG SDKEKYE
Sbjct: 533  KDAPIPECPVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGLSDKEKYE 592

Query: 1013 KARSLKKHIEGIRKAYTKDFGNKDLTKRQVAVATYLIDKLALRAGNEKDDDEADTVGCCT 834
            KAR LK +I+GIR AYTKDF +KD TK+Q+AVATYLIDKLALRAGNEKDDDEADTVGCCT
Sbjct: 593  KARLLKDYIQGIRAAYTKDFASKDPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCT 652

Query: 833  LKVENCEPVPPNILKFDFLGKDSIRYQNEVEVELPVFKAIQQFRTGKKGNDDLFDKLDTS 654
            LKVEN EPVPPNILKFDFLGKDSIRYQNEVEVE  VFKAIQQFR+GK+G+ DLFD LDTS
Sbjct: 653  LKVENVEPVPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSSDLFDLLDTS 712

Query: 653  TLNAHLKELMPGLTAKVFRTYNASITLDDMLDKGMKGESVAENVVVYNQANKQVAIICNH 474
             LNAHLKELMPGLTAKVFRTYNASITLDDML +  KG  VAE VVVY  ANK+VAIICNH
Sbjct: 713  KLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKEVAIICNH 772

Query: 473  QRSVSKSHGTQMTRLNEKIDELKALIEELETDLARAKKGKPPL--KGSDGKAKRNLNPEA 300
            QR+VSKSH  QM RLNEKI+ELKA++EEL++DL+R KKGKPPL  K +DGK KRNLNPE+
Sbjct: 773  QRTVSKSHSAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPKRNLNPES 832

Query: 299  IRKKIDQTNAKIDKMERDKETKEDLKTIALGTSKINYLDPRITVAWCKRSEVPIEKIFNK 120
            + KKI QTNAKI+KMERDKETKEDLKT+ALGTSKINYLDPRITVAWCKR EVPIEKIFNK
Sbjct: 833  LEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNK 892

Query: 119  SLLAKFAWSMDVDPSFRF 66
            SLLAKF W+MDVDPSFRF
Sbjct: 893  SLLAKFTWAMDVDPSFRF 910


>emb|CDP13767.1| unnamed protein product [Coffea canephora]
          Length = 926

 Score = 1066 bits (2756), Expect = 0.0
 Identities = 553/824 (67%), Positives = 625/824 (75%), Gaps = 31/824 (3%)
 Frame = -3

Query: 2444 SSTADKSKHSSQQKAAPTVKQEXXXXXXXXXXXSDTEDSEDDKPLSSRILTAPKGNS--- 2274
            SST+   K     K +P VK             +  EDS+DDKPL +++   P G+S   
Sbjct: 113  SSTSATVKQLENHKNSPVVKLPKRSVSAAKLSSTP-EDSDDDKPLMAKL---PSGSSRAI 168

Query: 2273 -NH-TKTGPPTSSSQRPKPPVKAKVKDEDSDDEKPLSLKITSKSSAGASINKHDDSDDDK 2100
             NH  K G  +S  Q+P        +DEDSDDEKPLS +  SKS+   SI+K  +  + K
Sbjct: 169  VNHGNKDGDGSSLVQKP-----GVEEDEDSDDEKPLSSRYLSKSNLVESISKSRNPGEKK 223

Query: 2099 PLSSRVKQNGSASRDNQIKKPSVGVNKRPPNEERSSGQSLVKKPKLSDSSTPINRKPAPA 1920
             L ++V+QNGSA RD  + K S   NKRPP E +SS +S VKKPKLS  +  IN+K A  
Sbjct: 224  SLPAKVQQNGSALRDGPVGKSSSLSNKRPPGEVKSSDESAVKKPKLSGPTAAINKKQATL 283

Query: 1919 KPEA--------------------------DTDDENDHVPISQRIKNQTPXXXXXXXXXX 1818
            K E                             DD++DHVPI+QR+K  T           
Sbjct: 284  KAEPKVEDDDDDILISQTAKKMFASASKPKSNDDDDDHVPITQRMKKSTTSVSQSSSVKK 343

Query: 1817 XXXXXXXSFLKKTNQKSKRVEKNSKYSKPSKVPPGSGEGQKWTSLAHNGVIFPPPYQPHG 1638
                   S LKKTN+KSK++ K SKYSK SKVPPGSGEGQKWT+L HNGVIFPPPY+PHG
Sbjct: 344  VAKVVSSS-LKKTNKKSKKIIKKSKYSKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHG 402

Query: 1637 VKILYKGKPVELTPEQEEVATMFAVMLDTDYMTKPVFKENFWNDWRKILGRNHTIQNLED 1458
            VK+LYKG+PV LTPEQEEVATMFAVMLDTDYM+KP FKENF++DW++ILG+NHTIQNLED
Sbjct: 403  VKMLYKGQPVTLTPEQEEVATMFAVMLDTDYMSKPQFKENFFSDWKRILGKNHTIQNLED 462

Query: 1457 CDFKPIYDWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAVVDGVKEKVGNFRVEPPG 1278
            CDF+PIY+WH                           KYMWA+VDGVKEKVGNFRVEPPG
Sbjct: 463  CDFRPIYEWHQKEKEKKKQMTTEEKKSLKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPG 522

Query: 1277 LFRGRGEHPKMGKLKKRIQPSDITINIGKGEPIPECPIPGQSWKEVRHDNTVTWLAYWND 1098
            LFRGRGEHPKMGKLKKRI+P DITINIGK  PIPECPIPG+ WKE+RHDNTVTWLA+WND
Sbjct: 523  LFRGRGEHPKMGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWND 582

Query: 1097 PINGKDFKYVFLAASSALKGQSDKEKYEKARSLKKHIEGIRKAYTKDFGNKDLTKRQVAV 918
            PIN K+FKYVFLAASS LKGQSDKEKYEKAR LK +I GIR AYTKDF +KD  K+Q+AV
Sbjct: 583  PINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRTAYTKDFASKDPMKKQIAV 642

Query: 917  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENCEPVPPNILKFDFLGKDSIRYQNEVEV 738
            ATYLIDKLALRAGNEKDDDEADTVGCCTLKVEN EPVPPNILKFDFLGKDSIRYQNEVEV
Sbjct: 643  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEV 702

Query: 737  ELPVFKAIQQFRTGKKGNDDLFDKLDTSTLNAHLKELMPGLTAKVFRTYNASITLDDMLD 558
            E  VFKAIQQFR+GK+G++DLFDKLDTS LNAHLKELMPGLTAKVFRTYNASITLDDML 
Sbjct: 703  ESGVFKAIQQFRSGKEGSEDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS 762

Query: 557  KGMKGESVAENVVVYNQANKQVAIICNHQRSVSKSHGTQMTRLNEKIDELKALIEELETD 378
            +   G  V E VVVY QANK+VAIICNHQR+VSK+H  QM+RLNEKI+ELK ++EEL+TD
Sbjct: 763  RKTNGGDVLEKVVVYQQANKEVAIICNHQRTVSKTHSAQMSRLNEKIEELKGVLEELKTD 822

Query: 377  LARAKKGKPPLKGSDGKAKRNLNPEAIRKKIDQTNAKIDKMERDKETKEDLKTIALGTSK 198
            L+RAKKGKPPLK +DGK KRNLNPEA+ +KI QTNAKI+KMERDKETKEDLKT+ALGTSK
Sbjct: 823  LSRAKKGKPPLKNADGKPKRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSK 882

Query: 197  INYLDPRITVAWCKRSEVPIEKIFNKSLLAKFAWSMDVDPSFRF 66
            INYLDPRITVAWCKR EVPIEKIFNKSLLAKFAWSMDVDPSFRF
Sbjct: 883  INYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWSMDVDPSFRF 926


>gb|KZV21640.1| DNA topoisomerase 1-like [Dorcoceras hygrometricum]
          Length = 870

 Score = 1059 bits (2739), Expect = 0.0
 Identities = 553/818 (67%), Positives = 623/818 (76%), Gaps = 5/818 (0%)
 Frame = -3

Query: 2504 LTNKMNYSSDEDDKPLVFKRSSTADKSKHSSQQKAAPTVKQ---EXXXXXXXXXXXSDTE 2334
            LT+  + SS   + P+   +SS A+  +  S+     +VKQ   E            D E
Sbjct: 69   LTSPKSSSSAAKESPV---KSSAANSKRPMSETDKPNSVKQQVKEEQPFAQAADETHDLE 125

Query: 2333 DSEDDKPLSSRIL-TAPKGNSNHTKTGPPTSSS-QRPKPPVKAKVKDEDSDDEKPLSLKI 2160
            DS DD PLS+R+L ++ KGNSNH K  P   +  Q+   P     K EDSDDE PLS K 
Sbjct: 126  DSGDDTPLSARLLASSSKGNSNHAKQRPNALALVQKNSIP-----KKEDSDDEMPLSSKF 180

Query: 2159 TSKSSAGASINKHDDSDDDKPLSSRVKQNGSASRDNQIKKPSVGVNKRPPNEERSSGQSL 1980
              KS    S ++ ++SD+ KP+ ++  QNGS+S D+  KKPS+ + KRPPN  +   +S 
Sbjct: 181  QVKSDVRVSTSRSNNSDERKPILNKADQNGSSSTDHSQKKPSIAM-KRPPNPVKVECRSP 239

Query: 1979 VKKPKLSDSSTPINRKPAPAKPEADTDDENDHVPISQRIKNQTPXXXXXXXXXXXXXXXX 1800
             KKPKLS++S+ I R    AKP+A+ DD  DHVPISQR+KNQ+                 
Sbjct: 240  EKKPKLSNASSAIPR----AKPKAEDDD--DHVPISQRMKNQSSSEKKSLSVKKVTKSVS 293

Query: 1799 XSFLKKTNQKSKRVEKNSKYSKPSKVPPGSGEGQKWTSLAHNGVIFPPPYQPHGVKILYK 1620
                 KTN+ SK++ KN+KYS  SKV P SGEGQKWT+L HNGVIFPPPY+PHGVK+LYK
Sbjct: 294  AV-ATKTNKISKKIVKNTKYSISSKVLPNSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYK 352

Query: 1619 GKPVELTPEQEEVATMFAVMLDTDYMTKPVFKENFWNDWRKILGRNHTIQNLEDCDFKPI 1440
            GKPV LTPEQEEVATMFAVMLDTDYM KP FKENF  DWRKILG+NHTIQ LEDCDF PI
Sbjct: 353  GKPVVLTPEQEEVATMFAVMLDTDYMNKPKFKENFMTDWRKILGKNHTIQKLEDCDFTPI 412

Query: 1439 YDWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAVVDGVKEKVGNFRVEPPGLFRGRG 1260
            Y+WH                           KYMWA++DGVKEKVGNFRVEPPGLFRGRG
Sbjct: 413  YEWHQKEKEKKKQMSTEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRG 472

Query: 1259 EHPKMGKLKKRIQPSDITINIGKGEPIPECPIPGQSWKEVRHDNTVTWLAYWNDPINGKD 1080
            EHPKMGKLKKRIQPSDI INIGK   IPECPIPG+SWKE+RHDNTVTWLAYWNDPIN K+
Sbjct: 473  EHPKMGKLKKRIQPSDIIINIGKDAAIPECPIPGESWKEIRHDNTVTWLAYWNDPINQKE 532

Query: 1079 FKYVFLAASSALKGQSDKEKYEKARSLKKHIEGIRKAYTKDFGNKDLTKRQVAVATYLID 900
            FKYVFLAASS LKGQSDKEKYEKAR LK +I+GIR AYTKDF +KD T++Q+AVATYLID
Sbjct: 533  FKYVFLAASSTLKGQSDKEKYEKARLLKNYIQGIRAAYTKDFSSKDPTRKQIAVATYLID 592

Query: 899  KLALRAGNEKDDDEADTVGCCTLKVENCEPVPPNILKFDFLGKDSIRYQNEVEVELPVFK 720
            KLALRAGNEKDDDEADTVGCCTLKVEN EPVPPNILKFDFLGKDSIRYQNEV VE  VFK
Sbjct: 593  KLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVVVETAVFK 652

Query: 719  AIQQFRTGKKGNDDLFDKLDTSTLNAHLKELMPGLTAKVFRTYNASITLDDMLDKGMKGE 540
            AIQQFR GKKG DDLFDKLDTS LNAHLKELMPGLTAKVFRTYNASITLDDML++  KG 
Sbjct: 653  AIQQFRNGKKGGDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLNRETKGG 712

Query: 539  SVAENVVVYNQANKQVAIICNHQRSVSKSHGTQMTRLNEKIDELKALIEELETDLARAKK 360
             VAE +VVY  ANK+VAIICNHQR+VSKSH  QM RL+EKIDELK  +EEL  DL+RAKK
Sbjct: 713  EVAEKIVVYQHANKEVAIICNHQRTVSKSHSAQMLRLDEKIDELKGAMEELREDLSRAKK 772

Query: 359  GKPPLKGSDGKAKRNLNPEAIRKKIDQTNAKIDKMERDKETKEDLKTIALGTSKINYLDP 180
            GKPPLK +DGK KRN+NPEA+ KKI QT AKI+KMERDKETKEDLKTIALGTS+INYLDP
Sbjct: 773  GKPPLKSADGKPKRNMNPEALEKKIAQTAAKIEKMERDKETKEDLKTIALGTSRINYLDP 832

Query: 179  RITVAWCKRSEVPIEKIFNKSLLAKFAWSMDVDPSFRF 66
            RITVAWCKR EVPIEKIFNKSLLAKFAW+MDVDP FRF
Sbjct: 833  RITVAWCKRQEVPIEKIFNKSLLAKFAWAMDVDPEFRF 870


>gb|PIN13662.1| DNA topoisomerase I [Handroanthus impetiginosus]
          Length = 895

 Score = 1055 bits (2728), Expect = 0.0
 Identities = 545/808 (67%), Positives = 613/808 (75%), Gaps = 2/808 (0%)
 Frame = -3

Query: 2483 SSDEDDKPLVFKRSSTADKSKHSSQQKAAPTVKQEXXXXXXXXXXXSDTEDSEDDKPLSS 2304
            SS  + KP     +S AD+S    QQ      + +            ++EDS+DDKPL++
Sbjct: 104  SSGVNSKP----STSVADESNSVKQQS-----RDKRPLTEATAELNEESEDSDDDKPLTA 154

Query: 2303 RILTA-PKGNSNHTKTGPPTSS-SQRPKPPVKAKVKDEDSDDEKPLSLKITSKSSAGASI 2130
            R+     K NSNH   GP  S   Q+PK P     K EDSDDE PLS K   KS+AG S 
Sbjct: 155  RLSAGFSKINSNHANKGPNASILGQKPKIP-----KSEDSDDEIPLSSKFQVKSNAGDSS 209

Query: 2129 NKHDDSDDDKPLSSRVKQNGSASRDNQIKKPSVGVNKRPPNEERSSGQSLVKKPKLSDSS 1950
             K   S   KPLS++   NG  S + +    ++ + KRP +  +S+G+S +K+PKLSD+S
Sbjct: 210  KKSPTSGGRKPLSAKCDHNGLGSPERKPSSSTI-LKKRPADGVKSAGESHLKRPKLSDAS 268

Query: 1949 TPINRKPAPAKPEADTDDENDHVPISQRIKNQTPXXXXXXXXXXXXXXXXXSFLKKTNQK 1770
                 K    K E   +D+ DHVPIS R+K  T                     KK N+K
Sbjct: 269  ASNKNKETSIKAELKEEDDEDHVPISARMKKSTSSDKKPSSSKNITKPVSS-LSKKINKK 327

Query: 1769 SKRVEKNSKYSKPSKVPPGSGEGQKWTSLAHNGVIFPPPYQPHGVKILYKGKPVELTPEQ 1590
            SK+V K S+YSK SKVPPGSGEGQKWT+L HNGVIFPPPY+PHGVK+LYKGKPV+LTPEQ
Sbjct: 328  SKKVTKKSEYSKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQ 387

Query: 1589 EEVATMFAVMLDTDYMTKPVFKENFWNDWRKILGRNHTIQNLEDCDFKPIYDWHXXXXXX 1410
            EEVATMFAVMLDTDYM KP FKENF +DWRKILG+NH IQ+LE C+F PIY+WH      
Sbjct: 388  EEVATMFAVMLDTDYMNKPKFKENFMDDWRKILGKNHVIQSLEHCNFTPIYEWHQKEKEK 447

Query: 1409 XXXXXXXXXXXXXXXXXXXXXKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKK 1230
                                 KYMWA+VDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKK
Sbjct: 448  KKQMSADEKKALKEEKLKQEDKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKK 507

Query: 1229 RIQPSDITINIGKGEPIPECPIPGQSWKEVRHDNTVTWLAYWNDPINGKDFKYVFLAASS 1050
            RI+PSDI INIGK  PIPECPIPG+SWKEVRHDNTVTWLAYWNDPIN K+FKYVFLAASS
Sbjct: 508  RIRPSDIVINIGKDAPIPECPIPGESWKEVRHDNTVTWLAYWNDPINPKEFKYVFLAASS 567

Query: 1049 ALKGQSDKEKYEKARSLKKHIEGIRKAYTKDFGNKDLTKRQVAVATYLIDKLALRAGNEK 870
            ALKGQSDKEKYEKAR LK +I+ IR  YTK+F +KD TK+Q+AVATYLIDKLALRAGNEK
Sbjct: 568  ALKGQSDKEKYEKARLLKDYIQDIRATYTKNFTSKDPTKKQIAVATYLIDKLALRAGNEK 627

Query: 869  DDDEADTVGCCTLKVENCEPVPPNILKFDFLGKDSIRYQNEVEVELPVFKAIQQFRTGKK 690
            DDDEADTVGCCTLKVEN EPVPPNILKFDFLGKDSIRYQNEVEVE  VF+AIQ+FR GKK
Sbjct: 628  DDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVETAVFRAIQEFRRGKK 687

Query: 689  GNDDLFDKLDTSTLNAHLKELMPGLTAKVFRTYNASITLDDMLDKGMKGESVAENVVVYN 510
            G DDLFDKLDTS LNAHLKELMPGLTAKVFRTYNASITLDDML +  KG  VAE VVVY 
Sbjct: 688  GGDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQ 747

Query: 509  QANKQVAIICNHQRSVSKSHGTQMTRLNEKIDELKALIEELETDLARAKKGKPPLKGSDG 330
             ANK+VAIICNHQR+VSKSH  QM RLNEKI+ELK ++EEL+TDLARAKKGKPPLK +DG
Sbjct: 748  LANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELQTDLARAKKGKPPLKNADG 807

Query: 329  KAKRNLNPEAIRKKIDQTNAKIDKMERDKETKEDLKTIALGTSKINYLDPRITVAWCKRS 150
            K KRNLNP+A+ +KI QT AKI+KMERDKETKEDLKT+ALGTSKINYLDPRITVAWCKR 
Sbjct: 808  KPKRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH 867

Query: 149  EVPIEKIFNKSLLAKFAWSMDVDPSFRF 66
            EVPIEKIFNKSLLAKFAW+MDVDPSFRF
Sbjct: 868  EVPIEKIFNKSLLAKFAWAMDVDPSFRF 895


>dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]
          Length = 927

 Score = 1052 bits (2721), Expect = 0.0
 Identities = 541/788 (68%), Positives = 608/788 (77%), Gaps = 29/788 (3%)
 Frame = -3

Query: 2342 DTEDSEDDKPLSSRIL-TAPKGNSNHT-KTGPPTSSSQRPKPPVKAKVKDEDSDDEKPLS 2169
            ++E S+D+KPLS+R    + KG SNH  K G  + S +R     +   + EDS+DEKPLS
Sbjct: 145  NSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSCSIRR-----RVIEESEDSEDEKPLS 199

Query: 2168 LKITSKSSAGASINKHDDSDDDKPLSSRVKQNGSASRDNQIKKPSVGVNKRPPNEERSSG 1989
             + TSKSS G S +K  DSD+ KPL+++V+QNGS SRD  + K +   NKRPP E +S  
Sbjct: 200  RRFTSKSSLGESTSKSYDSDEKKPLAAKVQQNGSVSRDGPMNKSASLSNKRPPGEVKSLN 259

Query: 1988 QSLVKKPKLSDSSTPINRKPAPAKPE----ADTDDEN----------------------D 1887
            QS VKKPKLS   T I+ K A  KPE    A+ DD+N                      D
Sbjct: 260  QSSVKKPKLSSPITSISNKQAAVKPEPEPKAEDDDDNIPLSQRGKKSQAATSKPKDEDDD 319

Query: 1886 HVPISQRIKNQTPXXXXXXXXXXXXXXXXXSFLKKTNQKSKRVEKNSKYSKPSKVPPGSG 1707
            +VPI+QRIK                       LKK N+ SK+V K + Y+K SKVPPGSG
Sbjct: 320  NVPIAQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKNSKKVIKKTAYTKSSKVPPGSG 379

Query: 1706 EGQKWTSLAHNGVIFPPPYQPHGVKILYKGKPVELTPEQEEVATMFAVMLDTDYMTKPVF 1527
            EGQKWT+L HNGVIFPPPY PHGVK+LYK +P+ LTPEQEEVATMFAVMLDTDYM KP F
Sbjct: 380  EGQKWTTLVHNGVIFPPPYNPHGVKMLYKRQPITLTPEQEEVATMFAVMLDTDYMNKPRF 439

Query: 1526 KENFWNDWRKILGRNHTIQNLEDCDFKPIYDWHXXXXXXXXXXXXXXXXXXXXXXXXXXX 1347
            KENF++DW+K+LG+NHTIQNLEDCDF PIY+WH                           
Sbjct: 440  KENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEKKALKEDKLQQEE 499

Query: 1346 KYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDITINIGKGEPIPECP 1167
            KYMWA+VDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI+P DITINIGK  PIPECP
Sbjct: 500  KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDITINIGKDAPIPECP 559

Query: 1166 IPGQSWKEVRHDNTVTWLAYWNDPINGKDFKYVFLAASSALKGQSDKEKYEKARSLKKHI 987
            IPG+ WKEVR+DNTVTWLA+W DPIN K+FKYVFLAASS LKGQSDKEKYEKAR LK +I
Sbjct: 560  IPGERWKEVRNDNTVTWLAFWIDPINQKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYI 619

Query: 986  EGIRKAYTKDF-GNKDLTKRQVAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENCEP 810
             GIR AYTKDF  NKD  K+Q+AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVEN EP
Sbjct: 620  HGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP 679

Query: 809  VPPNILKFDFLGKDSIRYQNEVEVELPVFKAIQQFRTGKKGNDDLFDKLDTSTLNAHLKE 630
            VPPNILKFDFLGKDSIRYQNEV+VE  VFKAIQQFR+GK+G++DLFD+LDTS LNAHLKE
Sbjct: 680  VPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKE 739

Query: 629  LMPGLTAKVFRTYNASITLDDMLDKGMKGESVAENVVVYNQANKQVAIICNHQRSVSKSH 450
            LMPGLTAKVFRTYNASITLDDML K  KG  VAE VVVY  ANK+VAIICNHQR+VSKSH
Sbjct: 740  LMPGLTAKVFRTYNASITLDDMLSKETKGGEVAEKVVVYQHANKEVAIICNHQRTVSKSH 799

Query: 449  GTQMTRLNEKIDELKALIEELETDLARAKKGKPPLKGSDGKAKRNLNPEAIRKKIDQTNA 270
              QM+RLNEKIDELK  +EEL+TDL+R KKGKPP KG+DGK KRNLNPEA+ +K+ Q NA
Sbjct: 800  SAQMSRLNEKIDELKTAMEELKTDLSRVKKGKPPSKGADGKPKRNLNPEALERKMAQINA 859

Query: 269  KIDKMERDKETKEDLKTIALGTSKINYLDPRITVAWCKRSEVPIEKIFNKSLLAKFAWSM 90
            KI+KMERDKETKEDLKT+ALGTSKINYLDPRITVAWCKR EVPIEKIFNKSLLAKFAWSM
Sbjct: 860  KIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWSM 919

Query: 89   DVDPSFRF 66
            DVDPSFRF
Sbjct: 920  DVDPSFRF 927


>dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. glabra]
          Length = 920

 Score = 1044 bits (2699), Expect = 0.0
 Identities = 537/779 (68%), Positives = 605/779 (77%), Gaps = 27/779 (3%)
 Frame = -3

Query: 2342 DTEDSEDDKPLSSRIL-TAPKGNSNHT-KTGPPTSSSQRPKPPVKAKVKDEDSDDEKPLS 2169
            ++E S+D+KPLS+R    + KG SNH  K G  + S +RP        + EDS+DEKPLS
Sbjct: 146  NSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSCSIRRP-----VIEESEDSEDEKPLS 200

Query: 2168 LKITSKSSAGASINKHDDSDDDKPLSSRVKQNGSASRDNQIKKPSVGVNKRPPNEERSSG 1989
             + TSKSS G S +K  DSD+ KPL+++V+ NGSASRD+ + K +   NKRPP E +S  
Sbjct: 201  RRFTSKSSLGESTSKSYDSDEKKPLAAKVQPNGSASRDSPMNKSASLSNKRPPGEVKSLN 260

Query: 1988 QSLVKKPKLSDSSTPINRKPAPAKPE--ADTDDEN----------------------DHV 1881
            QS +KKPKLS   T I+ K A  KPE  A+ DD+N                      D+V
Sbjct: 261  QSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQTATSKPKDEDDDNV 320

Query: 1880 PISQRIKNQTPXXXXXXXXXXXXXXXXXSFLKKTNQKSKRVEKNSKYSKPSKVPPGSGEG 1701
            PISQRIK                       LKK N+KSK+V K + Y+K SKVPPGSGEG
Sbjct: 321  PISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEG 380

Query: 1700 QKWTSLAHNGVIFPPPYQPHGVKILYKGKPVELTPEQEEVATMFAVMLDTDYMTKPVFKE 1521
            QKWT+L HNGVIFPPPY+PHGVK+LYK +P+ LTPEQEEVATMFAVMLDTDYM KP FKE
Sbjct: 381  QKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEVATMFAVMLDTDYMNKPRFKE 440

Query: 1520 NFWNDWRKILGRNHTIQNLEDCDFKPIYDWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKY 1341
            NF++DW+K+LG+NHTIQNLEDCDF PIY+WH                           KY
Sbjct: 441  NFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEKKALKEEKLQQEEKY 500

Query: 1340 MWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDITINIGKGEPIPECPIP 1161
            MWA+VDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI+P DITINIGK  PIPECPIP
Sbjct: 501  MWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDITINIGKDAPIPECPIP 560

Query: 1160 GQSWKEVRHDNTVTWLAYWNDPINGKDFKYVFLAASSALKGQSDKEKYEKARSLKKHIEG 981
            G+ WKEVR+DNTVTWLAYWNDPIN K+FKYVFLAASS LKGQSDKEKYEKAR LK +I G
Sbjct: 561  GERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHG 620

Query: 980  IRKAYTKDF-GNKDLTKRQVAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENCEPVP 804
            IR AYTKDF  NKD  K+Q+AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVEN EPVP
Sbjct: 621  IRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVP 680

Query: 803  PNILKFDFLGKDSIRYQNEVEVELPVFKAIQQFRTGKKGNDDLFDKLDTSTLNAHLKELM 624
            PNILKFDFLGKDSIRYQNEV+VE  VFKAIQQFR+GK+G++DLFD+LDTS LNAHLKELM
Sbjct: 681  PNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELM 740

Query: 623  PGLTAKVFRTYNASITLDDMLDKGMKGESVAENVVVYNQANKQVAIICNHQRSVSKSHGT 444
            PGLTAKVFRTYNASITLDDML K   G  VAE VVVY  ANK+VAIICNHQR+VSKSH  
Sbjct: 741  PGLTAKVFRTYNASITLDDMLSKKTNGGEVAEKVVVYQHANKEVAIICNHQRTVSKSHSA 800

Query: 443  QMTRLNEKIDELKALIEELETDLARAKKGKPPLKGSDGKAKRNLNPEAIRKKIDQTNAKI 264
            QM+RLNEKIDELK  +EEL+TDL+RAKKGKP  KG+DGK KRNLNPEA+ +KI QTNAKI
Sbjct: 801  QMSRLNEKIDELKTALEELKTDLSRAKKGKPLSKGADGKPKRNLNPEALERKIAQTNAKI 860

Query: 263  DKMERDKETKEDLKTIALGTSKINYLDPRITVAWCKRSEVPIEKIFNKSLLAKFAWSMD 87
            +KMERDKETKEDLKT+ALGTSKINYLDPRITVAWCKR EVPIEKIFNKSLLAKFAW+M+
Sbjct: 861  EKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMN 919


>dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]
          Length = 920

 Score = 1042 bits (2694), Expect = 0.0
 Identities = 536/779 (68%), Positives = 604/779 (77%), Gaps = 27/779 (3%)
 Frame = -3

Query: 2342 DTEDSEDDKPLSSRIL-TAPKGNSNHT-KTGPPTSSSQRPKPPVKAKVKDEDSDDEKPLS 2169
            ++E S+D+KPLS+R    + KG SNH  K G  + S +RP        + EDS+DEKPLS
Sbjct: 146  NSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSCSIRRP-----VIEESEDSEDEKPLS 200

Query: 2168 LKITSKSSAGASINKHDDSDDDKPLSSRVKQNGSASRDNQIKKPSVGVNKRPPNEERSSG 1989
             + TSKSS G S +K  DSD+ KPL+++V+ NGSASRD+ + K +   NKRPP E +S  
Sbjct: 201  RRFTSKSSLGESTSKSYDSDEKKPLAAKVQPNGSASRDSPMNKSASLSNKRPPGEVKSLN 260

Query: 1988 QSLVKKPKLSDSSTPINRKPAPAKPE--ADTDDEN----------------------DHV 1881
            QS +KKPKLS   T I+ K A  KPE  A+ DD+N                      D+V
Sbjct: 261  QSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQTATSKPKDEDDDNV 320

Query: 1880 PISQRIKNQTPXXXXXXXXXXXXXXXXXSFLKKTNQKSKRVEKNSKYSKPSKVPPGSGEG 1701
            PISQRIK                       LKK N+KSK+V K + Y+K SKVPPGSGEG
Sbjct: 321  PISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEG 380

Query: 1700 QKWTSLAHNGVIFPPPYQPHGVKILYKGKPVELTPEQEEVATMFAVMLDTDYMTKPVFKE 1521
            QKWT+L HNGVIFPPPY+PHGVK+LYK +P+ LTPEQEEVATMFAVMLDTDYM KP FKE
Sbjct: 381  QKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEVATMFAVMLDTDYMNKPRFKE 440

Query: 1520 NFWNDWRKILGRNHTIQNLEDCDFKPIYDWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKY 1341
            NF++DW+K+LG+NHTIQNLEDCDF PIY+WH                           KY
Sbjct: 441  NFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEKKALKEEKLQQEEKY 500

Query: 1340 MWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDITINIGKGEPIPECPIP 1161
            MWA+VDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI+P DITINIGK  PIPECPIP
Sbjct: 501  MWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDITINIGKDAPIPECPIP 560

Query: 1160 GQSWKEVRHDNTVTWLAYWNDPINGKDFKYVFLAASSALKGQSDKEKYEKARSLKKHIEG 981
            G+ WKEVR+DNTVTWLAYWNDPIN K+FKYVFLAASS LKGQSDKEKYEKAR LK +I G
Sbjct: 561  GERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHG 620

Query: 980  IRKAYTKDF-GNKDLTKRQVAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENCEPVP 804
            IR AYTKDF  NKD  K+Q+AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVEN EPVP
Sbjct: 621  IRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVP 680

Query: 803  PNILKFDFLGKDSIRYQNEVEVELPVFKAIQQFRTGKKGNDDLFDKLDTSTLNAHLKELM 624
            PNILKFDFLGKDSIRYQNEV+VE  VFKAI QFR+GK+G++DLFD+LDTS LNAHLKELM
Sbjct: 681  PNILKFDFLGKDSIRYQNEVQVEPAVFKAIHQFRSGKEGSEDLFDRLDTSKLNAHLKELM 740

Query: 623  PGLTAKVFRTYNASITLDDMLDKGMKGESVAENVVVYNQANKQVAIICNHQRSVSKSHGT 444
            PGLTAKVFRTYNASITLDDML K   G  VAE VVVY  ANK+VAIICNHQR+VSKSH  
Sbjct: 741  PGLTAKVFRTYNASITLDDMLSKKTNGGEVAEKVVVYQHANKEVAIICNHQRTVSKSHSA 800

Query: 443  QMTRLNEKIDELKALIEELETDLARAKKGKPPLKGSDGKAKRNLNPEAIRKKIDQTNAKI 264
            QM+RLNEKIDELK  +EEL+TDL+RAKKGKP  KG+DGK KRNLNPEA+ +KI QTNAKI
Sbjct: 801  QMSRLNEKIDELKTALEELKTDLSRAKKGKPLSKGADGKPKRNLNPEALERKIAQTNAKI 860

Query: 263  DKMERDKETKEDLKTIALGTSKINYLDPRITVAWCKRSEVPIEKIFNKSLLAKFAWSMD 87
            +KMERDKETKEDLKT+ALGTSKINYLDPRITVAWCKR EVPIEKIFNKSLLAKFAW+M+
Sbjct: 861  EKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMN 919


>ref|XP_023553297.1| DNA topoisomerase 1 beta-like [Cucurbita pepo subsp. pepo]
          Length = 887

 Score = 1039 bits (2686), Expect = 0.0
 Identities = 538/813 (66%), Positives = 616/813 (75%), Gaps = 7/813 (0%)
 Frame = -3

Query: 2483 SSDEDDKPLVFKRSST---ADKSKHSSQQKAAPTVKQEXXXXXXXXXXXSDTEDSEDDKP 2313
            S     +PLV    +T   +D      +Q A   VK+E            D  DSEDDKP
Sbjct: 91   SKSSIQEPLVKSLGTTLKVSDSMDSRPKQLANAAVKEENDSIHPTQ----DNSDSEDDKP 146

Query: 2312 LSSRILTAPKGNSNHTKTGP-PTSSSQRPKPPVKAKVKDEDSDDEKPLSLKITSKSSAGA 2136
            LS R+    KGNSNH   GP PT          K K   EDSDDE PLS K   KS++G 
Sbjct: 147  LSIRL----KGNSNHPSKGPIPTVQKN------KIKKSSEDSDDEVPLSSKFQMKSASGV 196

Query: 2135 SINKHDDSDDDKPLSSRVKQNGSASRDNQIKKPSVGVNKRP-PN-EERSSGQSLVKKPKL 1962
               +    D+ KPL S+V QNGS SRD +++KP+V  +KRP PN +  SS Q   KKPKL
Sbjct: 197  LGGRQHGFDEKKPLDSKVHQNGSTSRD-KLQKPAVVSSKRPLPNADSHSSSQISSKKPKL 255

Query: 1961 SDSSTPINRKPAPAKPEADTDDENDHVPISQRIKNQTPXXXXXXXXXXXXXXXXXSFLKK 1782
            SDSSTP++      K + +  D++DH+PISQR+K  +                  S +KK
Sbjct: 256  SDSSTPLSTNTVSLKAKQEVADDDDHIPISQRMK-MSAAVNKSSGSKKTVSKVASSSIKK 314

Query: 1781 TNQKSKRVEKNSKYSKPSKVPPGSGEGQK-WTSLAHNGVIFPPPYQPHGVKILYKGKPVE 1605
            T +KSK+  K SKY K +K+ P SG+GQK WT+L HNGVIFPPPYQ HGVKIL+KGKPV+
Sbjct: 315  TLKKSKKPVKKSKYVKSTKLLPSSGDGQKKWTTLVHNGVIFPPPYQTHGVKILHKGKPVD 374

Query: 1604 LTPEQEEVATMFAVMLDTDYMTKPVFKENFWNDWRKILGRNHTIQNLEDCDFKPIYDWHX 1425
            LTPEQEEVATMFAVM DTDYM KP FKENFWNDWRK+LG+NH IQNL+DCDF PIYDW+ 
Sbjct: 375  LTPEQEEVATMFAVMKDTDYMQKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQ 434

Query: 1424 XXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKM 1245
                                      KYMWA++DGVKEKVGNFRVEPPGLFRGRGEHPKM
Sbjct: 435  TEKEKKKQMTTEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKM 494

Query: 1244 GKLKKRIQPSDITINIGKGEPIPECPIPGQSWKEVRHDNTVTWLAYWNDPINGKDFKYVF 1065
            GKLKKRI+PSDITINIGK  PIPECPIPGQ WKEVRHDNTVTWLA+WNDPIN K+FKYVF
Sbjct: 495  GKLKKRIRPSDITINIGKDAPIPECPIPGQRWKEVRHDNTVTWLAFWNDPINPKEFKYVF 554

Query: 1064 LAASSALKGQSDKEKYEKARSLKKHIEGIRKAYTKDFGNKDLTKRQVAVATYLIDKLALR 885
            LAASS+LKGQSDKEKYEKAR LK +I+ IR +YTKDF +KD T+RQ+AVATYLIDKLALR
Sbjct: 555  LAASSSLKGQSDKEKYEKARMLKDYIKNIRNSYTKDFTSKDPTRRQIAVATYLIDKLALR 614

Query: 884  AGNEKDDDEADTVGCCTLKVENCEPVPPNILKFDFLGKDSIRYQNEVEVELPVFKAIQQF 705
            AGNEKDDDEADTVGCCTLKVEN + VPPN+L+F+FLGKDSI+Y+N VEVELPVFKAI QF
Sbjct: 615  AGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQF 674

Query: 704  RTGKKGNDDLFDKLDTSTLNAHLKELMPGLTAKVFRTYNASITLDDMLDKGMKGESVAEN 525
            ++GK G+DDLFDKLDTS LNAHLK+LMPGLTAKVFRTYNASITLDDML++G K   V+E 
Sbjct: 675  QSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTYNASITLDDMLNRGTKDGEVSEK 734

Query: 524  VVVYNQANKQVAIICNHQRSVSKSHGTQMTRLNEKIDELKALIEELETDLARAKKGKPPL 345
            +V Y  ANK+VAIICNHQR+VSKSHG QMTRLNEKI EL+ +++EL+ DL RAKKGKPPL
Sbjct: 735  IVTYQHANKEVAIICNHQRTVSKSHGAQMTRLNEKISELRDIVKELKIDLDRAKKGKPPL 794

Query: 344  KGSDGKAKRNLNPEAIRKKIDQTNAKIDKMERDKETKEDLKTIALGTSKINYLDPRITVA 165
            KGSDGK KRNL PEA+ KKI QTNAKI+K+ERD +TKEDLKT+ALGTSKINYLDPRITVA
Sbjct: 795  KGSDGKQKRNLTPEALEKKISQTNAKIEKIERDMKTKEDLKTVALGTSKINYLDPRITVA 854

Query: 164  WCKRSEVPIEKIFNKSLLAKFAWSMDVDPSFRF 66
            WCKR EVPIEKIFNKSLLAKFAW+MDVDP FRF
Sbjct: 855  WCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF 887


>ref|XP_009619726.2| PREDICTED: DNA topoisomerase 1-like [Nicotiana tomentosiformis]
 ref|XP_018631669.1| PREDICTED: DNA topoisomerase 1-like [Nicotiana tomentosiformis]
          Length = 877

 Score = 1038 bits (2683), Expect = 0.0
 Identities = 524/761 (68%), Positives = 604/761 (79%), Gaps = 2/761 (0%)
 Frame = -3

Query: 2342 DTEDSEDDKPLSSRILTA-PKGNSNHTKTGPPTSSS-QRPKPPVKAKVKDEDSDDEKPLS 2169
            + EDSEDDKPLS+R+ +   K NS+H      TS+S Q+ +PP     K EDSDDE PL+
Sbjct: 139  EAEDSEDDKPLSARLSSGLSKSNSSHANKVLGTSASVQKSRPP-----KKEDSDDEIPLA 193

Query: 2168 LKITSKSSAGASINKHDDSDDDKPLSSRVKQNGSASRDNQIKKPSVGVNKRPPNEERSSG 1989
             +   KS+AGAS +K  +S++ KP   +++QNG  S        +  ++KRPP + +S+ 
Sbjct: 194  SRFQLKSNAGASTSKSSNSEEVKP---KIRQNGLPS--------TTVLSKRPPGDVKSAA 242

Query: 1988 QSLVKKPKLSDSSTPINRKPAPAKPEADTDDENDHVPISQRIKNQTPXXXXXXXXXXXXX 1809
            Q+ VKKP+LSD+STP++ K A  KPE  T+D++D VPISQRIK                 
Sbjct: 243  QASVKKPRLSDASTPVSSKQASVKPEKKTEDDDDDVPISQRIKKSVASASKLSSAKKATK 302

Query: 1808 XXXXSFLKKTNQKSKRVEKNSKYSKPSKVPPGSGEGQKWTSLAHNGVIFPPPYQPHGVKI 1629
                  +  ++ K+K+  K SKYSK SK+ P SGEGQKWT+L HNGVIFPPPY+PHGVK+
Sbjct: 303  ------VVSSSMKTKKKLKKSKYSKSSKLQPSSGEGQKWTTLVHNGVIFPPPYKPHGVKM 356

Query: 1628 LYKGKPVELTPEQEEVATMFAVMLDTDYMTKPVFKENFWNDWRKILGRNHTIQNLEDCDF 1449
            LYKGKPV+LTPEQEEVATM+AVMLDTDYM+K  FKENF NDWRKILG+NH IQNL+DCDF
Sbjct: 357  LYKGKPVDLTPEQEEVATMYAVMLDTDYMSKLQFKENFMNDWRKILGKNHVIQNLDDCDF 416

Query: 1448 KPIYDWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAVVDGVKEKVGNFRVEPPGLFR 1269
             PIY+WH                           KYMWA+VDGVKEKVGNFRVEPPGLFR
Sbjct: 417  TPIYEWHQSEKEKKKQMSTEEKKALREEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFR 476

Query: 1268 GRGEHPKMGKLKKRIQPSDITINIGKGEPIPECPIPGQSWKEVRHDNTVTWLAYWNDPIN 1089
            GRGEHPKMGKLK+RI+P+DITINIGKG PIPECPIPG+ WKEVRHDNTVTWLA+WNDPIN
Sbjct: 477  GRGEHPKMGKLKRRIRPNDITINIGKGAPIPECPIPGERWKEVRHDNTVTWLAFWNDPIN 536

Query: 1088 GKDFKYVFLAASSALKGQSDKEKYEKARSLKKHIEGIRKAYTKDFGNKDLTKRQVAVATY 909
             ++FKYVFLAASS+LKGQSDKEKYEKAR LK +IEGIR AYTKDF +KD  KRQ+AVATY
Sbjct: 537  PREFKYVFLAASSSLKGQSDKEKYEKARRLKDYIEGIRSAYTKDFTSKDPVKRQIAVATY 596

Query: 908  LIDKLALRAGNEKDDDEADTVGCCTLKVENCEPVPPNILKFDFLGKDSIRYQNEVEVELP 729
            LIDKLALRAGNEKDDDEADTVGCCTLKVEN EPVPPNILKFDFLGKDSIRYQNEV V  P
Sbjct: 597  LIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVAVYEP 656

Query: 728  VFKAIQQFRTGKKGNDDLFDKLDTSTLNAHLKELMPGLTAKVFRTYNASITLDDMLDKGM 549
            VFKAIQ FR+GKKG DDLFDKLDTS LNAHLKELMPGLTAKVFRTYNAS+TL+  L K  
Sbjct: 657  VFKAIQLFRSGKKGGDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASVTLEQQLTKLT 716

Query: 548  KGESVAENVVVYNQANKQVAIICNHQRSVSKSHGTQMTRLNEKIDELKALIEELETDLAR 369
            +G  +AE V VYN ANK+VAIICNHQRSVSKSH  Q+++LNEKIDELKAL+EE + DLAR
Sbjct: 717  QGGELAEKVAVYNLANKEVAIICNHQRSVSKSHSVQISKLNEKIDELKALLEEFKVDLAR 776

Query: 368  AKKGKPPLKGSDGKAKRNLNPEAIRKKIDQTNAKIDKMERDKETKEDLKTIALGTSKINY 189
            AKKGKPPLKG+DGKAKRNL PEA++KKIDQTN KI+ +ER  ETKE+LKT+ALGTSKINY
Sbjct: 777  AKKGKPPLKGADGKAKRNLAPEALQKKIDQTNVKIENIERQIETKEELKTVALGTSKINY 836

Query: 188  LDPRITVAWCKRSEVPIEKIFNKSLLAKFAWSMDVDPSFRF 66
            LDPRITVAWCKR EVPIEK+FNKSLLAKFAW+MDV+PSF F
Sbjct: 837  LDPRITVAWCKRHEVPIEKMFNKSLLAKFAWAMDVEPSFTF 877


>dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]
          Length = 926

 Score = 1036 bits (2679), Expect = 0.0
 Identities = 532/786 (67%), Positives = 605/786 (76%), Gaps = 27/786 (3%)
 Frame = -3

Query: 2342 DTEDSEDDKPLSSRIL-TAPKGNSNHT-KTGPPTSSSQRPKPPVKAKVKDEDSDDEKPLS 2169
            ++E S+D+KPL +R    + KG SNH  K G  + S +RP        + EDS+DEKPLS
Sbjct: 146  NSESSDDEKPLIARTSGCSSKGKSNHANKEGGDSCSIRRP-----VIEESEDSEDEKPLS 200

Query: 2168 LKITSKSSAGASINKHDDSDDDKPLSSRVKQNGSASRDNQIKKPSVGVNKRPPNEERSSG 1989
             +  SKSS G S +K  DSD+ KPL+++V+QNGSASRD  + K +   NKR P E +S  
Sbjct: 201  RRFPSKSSLGESTSKSHDSDEKKPLAAKVQQNGSASRDGPMNKSASLSNKRAPGEVKSLN 260

Query: 1988 QSLVKKPKLSDSSTPINRKPAPAKPE--ADTDDEN----------------------DHV 1881
            QS +KKPKLS + T I+ K A  KPE  A+ DD+N                      D+ 
Sbjct: 261  QSSLKKPKLSSTITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQTAASKPKDEDDDNA 320

Query: 1880 PISQRIKNQTPXXXXXXXXXXXXXXXXXSFLKKTNQKSKRVEKNSKYSKPSKVPPGSGEG 1701
            PISQRIK                       LKK N+KSK+V K + Y+K SKVPPGSGEG
Sbjct: 321  PISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEG 380

Query: 1700 QKWTSLAHNGVIFPPPYQPHGVKILYKGKPVELTPEQEEVATMFAVMLDTDYMTKPVFKE 1521
            QKWT+L HNGV+FPPPY+PHGVK+LYK +P+ LTPEQEEVATMFA MLDTDYM KP FKE
Sbjct: 381  QKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQEEVATMFAAMLDTDYMNKPRFKE 440

Query: 1520 NFWNDWRKILGRNHTIQNLEDCDFKPIYDWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKY 1341
            NF++DW+KILG+NHTIQNLEDCDF PIY+WH                           KY
Sbjct: 441  NFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEKKALKEERLQLEEKY 500

Query: 1340 MWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDITINIGKGEPIPECPIP 1161
            MWA+VDGVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI+P DITINIGK  PIPECPIP
Sbjct: 501  MWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIRPRDITINIGKDAPIPECPIP 560

Query: 1160 GQSWKEVRHDNTVTWLAYWNDPINGKDFKYVFLAASSALKGQSDKEKYEKARSLKKHIEG 981
            G+ WKEVR+DNTVTWLAYWNDP+N K+ KYVFLAASS LKGQSDKEKYEKAR LK +I G
Sbjct: 561  GERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAASSTLKGQSDKEKYEKARLLKDYIHG 620

Query: 980  IRKAYTKDF-GNKDLTKRQVAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENCEPVP 804
            IR AYTKDF  NKD  K+QVAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVEN EPVP
Sbjct: 621  IRAAYTKDFTNNKDPMKKQVAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVP 680

Query: 803  PNILKFDFLGKDSIRYQNEVEVELPVFKAIQQFRTGKKGNDDLFDKLDTSTLNAHLKELM 624
            PNILK DF+GKDSIRYQNEV+VE  VFKAIQQFR+GK+G++DLFD+LDTS LNAHLKELM
Sbjct: 681  PNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELM 740

Query: 623  PGLTAKVFRTYNASITLDDMLDKGMKGESVAENVVVYNQANKQVAIICNHQRSVSKSHGT 444
            PGLTAKVFRTYNASITLDDML K  KG  VAE V VY +ANK+VAIICNHQR+VSKSH  
Sbjct: 741  PGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQRANKEVAIICNHQRTVSKSHSA 800

Query: 443  QMTRLNEKIDELKALIEELETDLARAKKGKPPLKGSDGKAKRNLNPEAIRKKIDQTNAKI 264
            QM+RLNEKIDELK  +EEL+TDL+RAKKGKPP KG DG+ KRNLNPEA+ +KI QTNAKI
Sbjct: 801  QMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGEPKRNLNPEALERKIAQTNAKI 860

Query: 263  DKMERDKETKEDLKTIALGTSKINYLDPRITVAWCKRSEVPIEKIFNKSLLAKFAWSMDV 84
            +KMERDK+TKEDLK +AL TSKI+YLDPRITVAWCKR EVPIEK+FNKSLLAKFAW+MDV
Sbjct: 861  EKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEVPIEKMFNKSLLAKFAWAMDV 920

Query: 83   DPSFRF 66
            DPSFRF
Sbjct: 921  DPSFRF 926