BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Chrysanthemum22_contig00013555
         (2175 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gb|KVH98657.1| BRCT domain-containing protein [Cynara cardunculu...   778   0.0  
ref|XP_022016124.1| DNA topoisomerase 2-binding protein 1 isofor...   771   0.0  
ref|XP_022016116.1| DNA topoisomerase 2-binding protein 1 isofor...   771   0.0  
ref|XP_023763409.1| DNA topoisomerase 2-binding protein 1 isofor...   761   0.0  
ref|XP_023763403.1| DNA topoisomerase 2-binding protein 1 isofor...   761   0.0  
ref|XP_023763396.1| DNA topoisomerase 2-binding protein 1 isofor...   761   0.0  
ref|XP_023763387.1| DNA topoisomerase 2-binding protein 1 isofor...   761   0.0  
ref|XP_023763415.1| DNA topoisomerase 2-binding protein 1 isofor...   739   0.0  
gb|OTG33974.1| putative transcription coactivator [Helianthus an...   727   0.0  
ref|XP_022016130.1| DNA topoisomerase 2-binding protein 1 isofor...   673   0.0  
ref|XP_023763423.1| DNA topoisomerase 2-binding protein 1 isofor...   664   0.0  
ref|XP_017981837.1| PREDICTED: DNA topoisomerase 2-binding prote...   598   0.0  
gb|EOY16438.1| Topbp1, putative isoform 5 [Theobroma cacao]           595   0.0  
gb|EOY16436.1| Topbp1, putative isoform 3 [Theobroma cacao]           595   0.0  
gb|EOY16437.1| Topbp1, putative isoform 4 [Theobroma cacao]           595   0.0  
gb|EOY16434.1| Topbp1, putative isoform 1 [Theobroma cacao]           595   0.0  
gb|EOY16435.1| Topbp1, putative isoform 2 [Theobroma cacao]           595   0.0  
ref|XP_016685711.1| PREDICTED: DNA topoisomerase 2-binding prote...   585   0.0  
ref|XP_016685710.1| PREDICTED: DNA topoisomerase 2-binding prote...   585   0.0  
ref|XP_012464227.1| PREDICTED: DNA topoisomerase 2-binding prote...   583   0.0  

>gb|KVH98657.1| BRCT domain-containing protein [Cynara cardunculus var. scolymus]
          Length = 959

 Score =  778 bits (2008), Expect = 0.0
 Identities = 392/580 (67%), Positives = 442/580 (76%)
 Frame = +1

Query: 1    NDYHIISSRDHEKFQDLRHKGCNLLGPLCVFSCAKENRMLPKQGFTCCLAMDGVKILASG 180
            NDYHIISSRDHE+F+DLR KGCNLLGP CV SCAKE+R+LPKQGFTCCLAMDGVK+LASG
Sbjct: 88   NDYHIISSRDHERFEDLREKGCNLLGPQCVLSCAKEHRVLPKQGFTCCLAMDGVKVLASG 147

Query: 181  FEMEAKVEIGKLVTAMGGMMLNKASSDVDFVIAKNVQAAKYKWALNTLKKPIVLESWLQL 360
            FEME KVEIGKLVTAMGG++  KASSDV FVI KNV AAKYKWALNTLKKPIV ESWL  
Sbjct: 148  FEMEGKVEIGKLVTAMGGVLQTKASSDVSFVIVKNVLAAKYKWALNTLKKPIVSESWLHQ 207

Query: 361  CWKEHHVVPHESYRAPSFSRLKRSVTQVPPAERKEIEMLVIQNGGIYSAELTKKSTHLVC 540
            CWKEH VVPHESYR   F  L  SVTQVP   RKEIE LV+QNGG YSAELT+KS     
Sbjct: 208  CWKEHRVVPHESYRVLPFFGLTISVTQVPLDARKEIEKLVLQNGGKYSAELTRKS----- 262

Query: 541  DAPEGDKYKVAKKWGHPHIVTRAWFNHSVARRACLNEESYPVQKGVATSANSHKNSLKA* 720
                 DKYKVAK+WGH HIVTRAWF+ SVARRACL+EESYPVQ+   TS NS + SL   
Sbjct: 263  -----DKYKVAKRWGHIHIVTRAWFDQSVARRACLSEESYPVQRSPVTSMNSQRTSLTVQ 317

Query: 721  HNQNKVVRNSQCGPHSTTHQEISCDGVPDADVETTLSQNMASTISDISVPVSEDCTPPCI 900
             +Q+KV RNSQCGPHS THQEISCDG+ DAD+E TLSQNMAST SDI + ++ED   P I
Sbjct: 318  RSQDKVTRNSQCGPHSMTHQEISCDGMADADLEATLSQNMASTFSDIPIFINEDNRVPSI 377

Query: 901  QPNNSMNIDNCVAEXXXXXXXXXXXXXCKIHIVGFDASEMRKLVNMVRRGGGSRYMSLNE 1080
            QP +S+NID CVA+             CKIH+VGFDASEMR+LVNMVRRG GSRYMSLNE
Sbjct: 378  QPKSSVNIDGCVAKDSQSEDNDLYLLNCKIHLVGFDASEMRRLVNMVRRGAGSRYMSLNE 437

Query: 1081 QLTHIVVGNPSESEKKEVRSLSAMGVINVVRTVWLEDCERQKKEVPVHRRHVAYDLLLPK 1260
            QLTHIVVG PSE+EKKEVRSLSAMGVINVVRTVWLEDCER+KKE+PV RRHVAYDLLLPK
Sbjct: 438  QLTHIVVGTPSETEKKEVRSLSAMGVINVVRTVWLEDCEREKKEIPVLRRHVAYDLLLPK 497

Query: 1261 DTISSNKGSVSTMSGPKQGKPTSIQPTLPNNXXXXXXXXXXXXXXXXXXXXXEIKXXXXX 1440
            D+ S +KGSVS + GPKQG  +++QP LP++                     +       
Sbjct: 498  DSTSFSKGSVSAIPGPKQGNLSTLQPILPSDQSQSFNKGQQTVQHGIRNESQDNVSSVFR 557

Query: 1441 XXXXXXXXXXPDVQRPEVVDWIQEGGGEVVDTQGVKNVDYTVESHGVLCNPAQFSGVTNV 1620
                      PDVQR E+VDWI EGGGEVVDT+  K V+YTVE+HGVLC+P+QFSGVTNV
Sbjct: 558  GRSFRFSSSFPDVQRAEIVDWIHEGGGEVVDTRAEKTVNYTVETHGVLCSPSQFSGVTNV 617

Query: 1621 SSHWIRSCLQDGHLLDISSHVSFLHFNAKFLYLGLLGFNY 1740
            SSHWIRSCLQDG+LLD+SSH+ F     K    G +G ++
Sbjct: 618  SSHWIRSCLQDGYLLDVSSHILFSPLQCKVPLPGFIGLHF 657



 Score =  164 bits (416), Expect = 2e-38
 Identities = 71/87 (81%), Positives = 82/87 (94%)
 Frame = +3

Query: 1683 LFSPLQCKVPLPGFIGLQLCVSQYEEKDRELLRSLCHVLGGRLNNKLTKKINYLVCKFSG 1862
            LFSPLQCKVPLPGFIGL  CVSQYEEKDRELLR+LCH+LGGRL N+LTKK+NYL+CKF+ 
Sbjct: 639  LFSPLQCKVPLPGFIGLHFCVSQYEEKDRELLRNLCHILGGRLVNRLTKKVNYLICKFTE 698

Query: 1863 GPKYEAACQWGMQSVTIEWIWECVKQD 1943
            GPKY AAC+WG+Q+VTI+WIWECVKQ+
Sbjct: 699  GPKYVAACEWGIQTVTIKWIWECVKQN 725


>ref|XP_022016124.1| DNA topoisomerase 2-binding protein 1 isoform X2 [Helianthus annuus]
          Length = 932

 Score =  771 bits (1992), Expect = 0.0
 Identities = 396/582 (68%), Positives = 437/582 (75%), Gaps = 2/582 (0%)
 Frame = +1

Query: 1    NDYHIISSRDHEKFQDLRHKGCNLLGPLCVFSCAKENRMLPKQGFTCCLAMDGVKILASG 180
            ND+HIISSRDHEKF DLR KGCNLLGP CVFSCAKENR+LPKQGFTCCLAMDGVKILASG
Sbjct: 49   NDFHIISSRDHEKFNDLRQKGCNLLGPQCVFSCAKENRVLPKQGFTCCLAMDGVKILASG 108

Query: 181  FEMEAKVEIGKLVTAMGGMMLNKASSDVDFVIAKNVQAAKYKWALNTLKKPIVLESWLQL 360
            FEM+ K EIGKLVTAMGG++  KASSDV FVI KNV AAKYKWALN LKKPIV +SWL  
Sbjct: 109  FEMKEKDEIGKLVTAMGGVLQTKASSDVSFVIVKNVLAAKYKWALNNLKKPIVSDSWLHR 168

Query: 361  CWKEHHVVPHESYRAPSFSRLKRSVTQVPPAERKEIEMLVIQNGGIYSAELTKKSTHLVC 540
            CWKEH VV HE YR   FS L  SVTQVP  ERKEIE LV QNGG YSAELT+KSTHLVC
Sbjct: 169  CWKEHRVVSHEPYRTLPFSGLTISVTQVPLDERKEIEKLVQQNGGKYSAELTRKSTHLVC 228

Query: 541  DAPEGDKYKVAKKWGHPHIVTRAWFNHSVARRACLNEESYPVQKGVATSANSHKNSLKA* 720
            DAPEGDKYKVAK+WGH HIV+R WFN SVARRACLNEESYPVQK   TS NS + S    
Sbjct: 229  DAPEGDKYKVAKRWGHIHIVSRTWFNQSVARRACLNEESYPVQKTSVTSTNSQRTS---- 284

Query: 721  HNQNKVVRNSQCGPHSTTHQEISCDGVPDADVETTLSQNMASTISDISVPVSED--CTPP 894
               +KVV+N++     +++QEISCDG+ DAD+E TLSQNMASTISDI VPVS+D   TPP
Sbjct: 285  ---SKVVKNAE----GSSYQEISCDGMVDADLEATLSQNMASTISDIPVPVSDDNTSTPP 337

Query: 895  CIQPNNSMNIDNCVAEXXXXXXXXXXXXXCKIHIVGFDASEMRKLVNMVRRGGGSRYMSL 1074
            C+Q   S NID CVAE             CKIH+VGFDASEMR+LVNMVRRGGGSRYMSL
Sbjct: 338  CVQHKTSFNIDACVAEDSQSEDNDLYLLNCKIHLVGFDASEMRRLVNMVRRGGGSRYMSL 397

Query: 1075 NEQLTHIVVGNPSESEKKEVRSLSAMGVINVVRTVWLEDCERQKKEVPVHRRHVAYDLLL 1254
            NEQLTHIVVG+PSESEKKEVRSLSAMGVINVV+TVWLEDCER+KKE+ V RRH AYDLLL
Sbjct: 398  NEQLTHIVVGSPSESEKKEVRSLSAMGVINVVKTVWLEDCEREKKEISVLRRHAAYDLLL 457

Query: 1255 PKDTISSNKGSVSTMSGPKQGKPTSIQPTLPNNXXXXXXXXXXXXXXXXXXXXXEIKXXX 1434
            PKD+IS NKGSV+ + G KQG P++IQP   N+                     E K   
Sbjct: 458  PKDSISYNKGSVNGIPGLKQGNPSTIQPAFSNDLSKSLSEGRQRTQHVISNKSQEKKSSV 517

Query: 1435 XXXXXXXXXXXXPDVQRPEVVDWIQEGGGEVVDTQGVKNVDYTVESHGVLCNPAQFSGVT 1614
                        PDVQR E+VDWI EGGGEVVD+Q  K VDYTVE+HGVLC P Q +G T
Sbjct: 518  FIGRSFRFSSSFPDVQRGEIVDWIHEGGGEVVDSQTKKIVDYTVEAHGVLCRPTQLTGAT 577

Query: 1615 NVSSHWIRSCLQDGHLLDISSHVSFLHFNAKFLYLGLLGFNY 1740
            NVS HWIRSCLQDGHLLD+ SH+ F     K    G +G  +
Sbjct: 578  NVSPHWIRSCLQDGHLLDVRSHLLFSPLQCKVPLPGFIGLQF 619



 Score =  172 bits (437), Expect = 4e-41
 Identities = 77/87 (88%), Positives = 83/87 (95%)
 Frame = +3

Query: 1683 LFSPLQCKVPLPGFIGLQLCVSQYEEKDRELLRSLCHVLGGRLNNKLTKKINYLVCKFSG 1862
            LFSPLQCKVPLPGFIGLQ CVSQYEEKDRELLR+LCHVLGG+L  KLTKK+NYL+CKFS 
Sbjct: 601  LFSPLQCKVPLPGFIGLQFCVSQYEEKDRELLRNLCHVLGGKLIKKLTKKVNYLICKFSE 660

Query: 1863 GPKYEAACQWGMQSVTIEWIWECVKQD 1943
            GPKYEAACQWGMQ+VTIEWIWECVKQ+
Sbjct: 661  GPKYEAACQWGMQTVTIEWIWECVKQN 687


>ref|XP_022016116.1| DNA topoisomerase 2-binding protein 1 isoform X1 [Helianthus annuus]
          Length = 933

 Score =  771 bits (1992), Expect = 0.0
 Identities = 396/582 (68%), Positives = 437/582 (75%), Gaps = 2/582 (0%)
 Frame = +1

Query: 1    NDYHIISSRDHEKFQDLRHKGCNLLGPLCVFSCAKENRMLPKQGFTCCLAMDGVKILASG 180
            ND+HIISSRDHEKF DLR KGCNLLGP CVFSCAKENR+LPKQGFTCCLAMDGVKILASG
Sbjct: 49   NDFHIISSRDHEKFNDLRQKGCNLLGPQCVFSCAKENRVLPKQGFTCCLAMDGVKILASG 108

Query: 181  FEMEAKVEIGKLVTAMGGMMLNKASSDVDFVIAKNVQAAKYKWALNTLKKPIVLESWLQL 360
            FEM+ K EIGKLVTAMGG++  KASSDV FVI KNV AAKYKWALN LKKPIV +SWL  
Sbjct: 109  FEMKEKDEIGKLVTAMGGVLQTKASSDVSFVIVKNVLAAKYKWALNNLKKPIVSDSWLHR 168

Query: 361  CWKEHHVVPHESYRAPSFSRLKRSVTQVPPAERKEIEMLVIQNGGIYSAELTKKSTHLVC 540
            CWKEH VV HE YR   FS L  SVTQVP  ERKEIE LV QNGG YSAELT+KSTHLVC
Sbjct: 169  CWKEHRVVSHEPYRTLPFSGLTISVTQVPLDERKEIEKLVQQNGGKYSAELTRKSTHLVC 228

Query: 541  DAPEGDKYKVAKKWGHPHIVTRAWFNHSVARRACLNEESYPVQKGVATSANSHKNSLKA* 720
            DAPEGDKYKVAK+WGH HIV+R WFN SVARRACLNEESYPVQK   TS NS + S    
Sbjct: 229  DAPEGDKYKVAKRWGHIHIVSRTWFNQSVARRACLNEESYPVQKTSVTSTNSQRTS---- 284

Query: 721  HNQNKVVRNSQCGPHSTTHQEISCDGVPDADVETTLSQNMASTISDISVPVSED--CTPP 894
               +KVV+N++     +++QEISCDG+ DAD+E TLSQNMASTISDI VPVS+D   TPP
Sbjct: 285  ---SKVVKNAE----GSSYQEISCDGMVDADLEATLSQNMASTISDIPVPVSDDNTSTPP 337

Query: 895  CIQPNNSMNIDNCVAEXXXXXXXXXXXXXCKIHIVGFDASEMRKLVNMVRRGGGSRYMSL 1074
            C+Q   S NID CVAE             CKIH+VGFDASEMR+LVNMVRRGGGSRYMSL
Sbjct: 338  CVQHKTSFNIDACVAEDSQSEDNDLYLLNCKIHLVGFDASEMRRLVNMVRRGGGSRYMSL 397

Query: 1075 NEQLTHIVVGNPSESEKKEVRSLSAMGVINVVRTVWLEDCERQKKEVPVHRRHVAYDLLL 1254
            NEQLTHIVVG+PSESEKKEVRSLSAMGVINVV+TVWLEDCER+KKE+ V RRH AYDLLL
Sbjct: 398  NEQLTHIVVGSPSESEKKEVRSLSAMGVINVVKTVWLEDCEREKKEISVLRRHAAYDLLL 457

Query: 1255 PKDTISSNKGSVSTMSGPKQGKPTSIQPTLPNNXXXXXXXXXXXXXXXXXXXXXEIKXXX 1434
            PKD+IS NKGSV+ + G KQG P++IQP   N+                     E K   
Sbjct: 458  PKDSISYNKGSVNGIPGLKQGNPSTIQPAFSNDLSKSLSEGRQRTQHVISNKSQEKKSSV 517

Query: 1435 XXXXXXXXXXXXPDVQRPEVVDWIQEGGGEVVDTQGVKNVDYTVESHGVLCNPAQFSGVT 1614
                        PDVQR E+VDWI EGGGEVVD+Q  K VDYTVE+HGVLC P Q +G T
Sbjct: 518  FIGRSFRFSSSFPDVQRGEIVDWIHEGGGEVVDSQTKKIVDYTVEAHGVLCRPTQLTGAT 577

Query: 1615 NVSSHWIRSCLQDGHLLDISSHVSFLHFNAKFLYLGLLGFNY 1740
            NVS HWIRSCLQDGHLLD+ SH+ F     K    G +G  +
Sbjct: 578  NVSPHWIRSCLQDGHLLDVRSHLLFSPLQCKVPLPGFIGLQF 619



 Score =  172 bits (437), Expect = 4e-41
 Identities = 77/87 (88%), Positives = 83/87 (95%)
 Frame = +3

Query: 1683 LFSPLQCKVPLPGFIGLQLCVSQYEEKDRELLRSLCHVLGGRLNNKLTKKINYLVCKFSG 1862
            LFSPLQCKVPLPGFIGLQ CVSQYEEKDRELLR+LCHVLGG+L  KLTKK+NYL+CKFS 
Sbjct: 601  LFSPLQCKVPLPGFIGLQFCVSQYEEKDRELLRNLCHVLGGKLIKKLTKKVNYLICKFSE 660

Query: 1863 GPKYEAACQWGMQSVTIEWIWECVKQD 1943
            GPKYEAACQWGMQ+VTIEWIWECVKQ+
Sbjct: 661  GPKYEAACQWGMQTVTIEWIWECVKQN 687


>ref|XP_023763409.1| DNA topoisomerase 2-binding protein 1 isoform X4 [Lactuca sativa]
          Length = 953

 Score =  761 bits (1966), Expect = 0.0
 Identities = 387/582 (66%), Positives = 434/582 (74%), Gaps = 2/582 (0%)
 Frame = +1

Query: 1    NDYHIISSRDHEKFQDLRHKGCNLLGPLCVFSCAKENRMLPKQGFTCCLAMDGVKILASG 180
            +DYHIISSRDHEKF DLR KGCNL+GP CVFSCAKENR+LPKQGFTCCLAMDGV IL SG
Sbjct: 50   DDYHIISSRDHEKFNDLRQKGCNLIGPQCVFSCAKENRVLPKQGFTCCLAMDGVNILTSG 109

Query: 181  FEMEAKVEIGKLVTAMGGMMLNKASSDVDFVIAKNVQAAKYKWALNTLKKPIVLESWLQL 360
            FE E K E+ KLVTAMGG++  KAS D++FVI KNV AAKYKWALN LKKPIV ESWL  
Sbjct: 110  FEKEGKDELDKLVTAMGGLLQTKASMDINFVIVKNVLAAKYKWALNALKKPIVSESWLHQ 169

Query: 361  CWKEHHVVPHESYRAPSFSRLKRSVTQVPPAERKEIEMLVIQNGGIYSAELTKKSTHLVC 540
            CWKEH VVPH+SYR   FS L  SVTQVP   RKEIE LVIQNGG YSAELT+KSTHLVC
Sbjct: 170  CWKEHRVVPHDSYRVLPFSGLTISVTQVPLDARKEIEKLVIQNGGKYSAELTRKSTHLVC 229

Query: 541  DAPEGDKYKVAKKWGHPHIVTRAWFNHSVARRACLNEESYPVQKGVATSANSHKNSLKA* 720
            DAPEGDKYKVAK+WGH  IVTR WF+ SVARRACLNE+SYPVQ+   TS NS + SLK  
Sbjct: 230  DAPEGDKYKVAKRWGHIRIVTRTWFDQSVARRACLNEDSYPVQRSPGTSMNSQRTSLKMQ 289

Query: 721  HNQNKVVRNSQCGPHSTTHQEISCDGVPDADVETTLSQNMASTISDISVPVSEDCTPPCI 900
            H+Q KV+RNSQ  P S THQEISCDG+ DAD+E TLSQNMAST SDI   +SE+ T P I
Sbjct: 290  HSQEKVIRNSQGAPISITHQEISCDGMADADLEATLSQNMASTCSDIPGIISEEKTTPTI 349

Query: 901  QPNNSMNIDNCVAEXXXXXXXXXXXXXCKIHIVGFDASEMRKLVNMVRRGGGSRYMSLNE 1080
            QP   M+ID CVAE             CKIH+VGFDA EMR+LVNMVRRG GSRYMSLN+
Sbjct: 350  QPKTCMDIDGCVAEDSQSEGNDLYFLNCKIHLVGFDAPEMRRLVNMVRRGSGSRYMSLND 409

Query: 1081 QLTHIVVGNPSESEKKEVRSLSAMGVINVVRTVWLEDCERQKKEVPVHRRHVAYDLLLPK 1260
            QLTHIVVG PSE+EKKEVRSLSAMGVINVV+TVWLEDCER+KKE+PV RRHVAYDLLLPK
Sbjct: 410  QLTHIVVGTPSETEKKEVRSLSAMGVINVVKTVWLEDCEREKKELPVLRRHVAYDLLLPK 469

Query: 1261 DTISSNKGSVSTMSGPKQGKPTSIQPTLPNNXXXXXXXXXXXXXXXXXXXXXE--IKXXX 1434
            D++  NKG VS + G KQG  +++QP L N+                     +   K   
Sbjct: 470  DSMPFNKGFVSAIPGLKQGNTSTVQPPLQNDQSQSQSLDKGQQKVQHGINNEKQNNKSSV 529

Query: 1435 XXXXXXXXXXXXPDVQRPEVVDWIQEGGGEVVDTQGVKNVDYTVESHGVLCNPAQFSGVT 1614
                        PDVQR E+VDWI EGGG+VVDT   KNV+YTVE+HGVLC+  QF+GVT
Sbjct: 530  FRGRSFRFSSTFPDVQRGEIVDWIHEGGGKVVDTLTEKNVNYTVEAHGVLCSRTQFNGVT 589

Query: 1615 NVSSHWIRSCLQDGHLLDISSHVSFLHFNAKFLYLGLLGFNY 1740
            NVSSHWIRSCLQDG LLD+SS++ F     K    G  G  +
Sbjct: 590  NVSSHWIRSCLQDGCLLDVSSYILFSPLQCKIPLPGFTGLQF 631



 Score =  143 bits (361), Expect = 1e-31
 Identities = 59/87 (67%), Positives = 77/87 (88%)
 Frame = +3

Query: 1683 LFSPLQCKVPLPGFIGLQLCVSQYEEKDRELLRSLCHVLGGRLNNKLTKKINYLVCKFSG 1862
            LFSPLQCK+PLPGF GLQ CVSQYE+K++ELLR++CHVLGG+L  +LTKK+NYL+CKF+ 
Sbjct: 613  LFSPLQCKIPLPGFTGLQFCVSQYEDKEKELLRNVCHVLGGKLVKRLTKKVNYLICKFTE 672

Query: 1863 GPKYEAACQWGMQSVTIEWIWECVKQD 1943
            GPK+EAA +WG+ +VT EW+WE + Q+
Sbjct: 673  GPKFEAAREWGVHTVTTEWLWESINQN 699


>ref|XP_023763403.1| DNA topoisomerase 2-binding protein 1 isoform X3 [Lactuca sativa]
          Length = 954

 Score =  761 bits (1966), Expect = 0.0
 Identities = 387/582 (66%), Positives = 434/582 (74%), Gaps = 2/582 (0%)
 Frame = +1

Query: 1    NDYHIISSRDHEKFQDLRHKGCNLLGPLCVFSCAKENRMLPKQGFTCCLAMDGVKILASG 180
            +DYHIISSRDHEKF DLR KGCNL+GP CVFSCAKENR+LPKQGFTCCLAMDGV IL SG
Sbjct: 50   DDYHIISSRDHEKFNDLRQKGCNLIGPQCVFSCAKENRVLPKQGFTCCLAMDGVNILTSG 109

Query: 181  FEMEAKVEIGKLVTAMGGMMLNKASSDVDFVIAKNVQAAKYKWALNTLKKPIVLESWLQL 360
            FE E K E+ KLVTAMGG++  KAS D++FVI KNV AAKYKWALN LKKPIV ESWL  
Sbjct: 110  FEKEGKDELDKLVTAMGGLLQTKASMDINFVIVKNVLAAKYKWALNALKKPIVSESWLHQ 169

Query: 361  CWKEHHVVPHESYRAPSFSRLKRSVTQVPPAERKEIEMLVIQNGGIYSAELTKKSTHLVC 540
            CWKEH VVPH+SYR   FS L  SVTQVP   RKEIE LVIQNGG YSAELT+KSTHLVC
Sbjct: 170  CWKEHRVVPHDSYRVLPFSGLTISVTQVPLDARKEIEKLVIQNGGKYSAELTRKSTHLVC 229

Query: 541  DAPEGDKYKVAKKWGHPHIVTRAWFNHSVARRACLNEESYPVQKGVATSANSHKNSLKA* 720
            DAPEGDKYKVAK+WGH  IVTR WF+ SVARRACLNE+SYPVQ+   TS NS + SLK  
Sbjct: 230  DAPEGDKYKVAKRWGHIRIVTRTWFDQSVARRACLNEDSYPVQRSPGTSMNSQRTSLKMQ 289

Query: 721  HNQNKVVRNSQCGPHSTTHQEISCDGVPDADVETTLSQNMASTISDISVPVSEDCTPPCI 900
            H+Q KV+RNSQ  P S THQEISCDG+ DAD+E TLSQNMAST SDI   +SE+ T P I
Sbjct: 290  HSQEKVIRNSQGAPISITHQEISCDGMADADLEATLSQNMASTCSDIPGIISEEKTTPTI 349

Query: 901  QPNNSMNIDNCVAEXXXXXXXXXXXXXCKIHIVGFDASEMRKLVNMVRRGGGSRYMSLNE 1080
            QP   M+ID CVAE             CKIH+VGFDA EMR+LVNMVRRG GSRYMSLN+
Sbjct: 350  QPKTCMDIDGCVAEDSQSEGNDLYFLNCKIHLVGFDAPEMRRLVNMVRRGSGSRYMSLND 409

Query: 1081 QLTHIVVGNPSESEKKEVRSLSAMGVINVVRTVWLEDCERQKKEVPVHRRHVAYDLLLPK 1260
            QLTHIVVG PSE+EKKEVRSLSAMGVINVV+TVWLEDCER+KKE+PV RRHVAYDLLLPK
Sbjct: 410  QLTHIVVGTPSETEKKEVRSLSAMGVINVVKTVWLEDCEREKKELPVLRRHVAYDLLLPK 469

Query: 1261 DTISSNKGSVSTMSGPKQGKPTSIQPTLPNNXXXXXXXXXXXXXXXXXXXXXE--IKXXX 1434
            D++  NKG VS + G KQG  +++QP L N+                     +   K   
Sbjct: 470  DSMPFNKGFVSAIPGLKQGNTSTVQPPLQNDQSQSQSLDKGQQKVQHGINNEKQNNKSSV 529

Query: 1435 XXXXXXXXXXXXPDVQRPEVVDWIQEGGGEVVDTQGVKNVDYTVESHGVLCNPAQFSGVT 1614
                        PDVQR E+VDWI EGGG+VVDT   KNV+YTVE+HGVLC+  QF+GVT
Sbjct: 530  FRGRSFRFSSTFPDVQRGEIVDWIHEGGGKVVDTLTEKNVNYTVEAHGVLCSRTQFNGVT 589

Query: 1615 NVSSHWIRSCLQDGHLLDISSHVSFLHFNAKFLYLGLLGFNY 1740
            NVSSHWIRSCLQDG LLD+SS++ F     K    G  G  +
Sbjct: 590  NVSSHWIRSCLQDGCLLDVSSYILFSPLQCKIPLPGFTGLQF 631



 Score =  143 bits (361), Expect = 1e-31
 Identities = 59/87 (67%), Positives = 77/87 (88%)
 Frame = +3

Query: 1683 LFSPLQCKVPLPGFIGLQLCVSQYEEKDRELLRSLCHVLGGRLNNKLTKKINYLVCKFSG 1862
            LFSPLQCK+PLPGF GLQ CVSQYE+K++ELLR++CHVLGG+L  +LTKK+NYL+CKF+ 
Sbjct: 613  LFSPLQCKIPLPGFTGLQFCVSQYEDKEKELLRNVCHVLGGKLVKRLTKKVNYLICKFTE 672

Query: 1863 GPKYEAACQWGMQSVTIEWIWECVKQD 1943
            GPK+EAA +WG+ +VT EW+WE + Q+
Sbjct: 673  GPKFEAAREWGVHTVTTEWLWESINQN 699


>ref|XP_023763396.1| DNA topoisomerase 2-binding protein 1 isoform X2 [Lactuca sativa]
 gb|PLY98445.1| hypothetical protein LSAT_1X6740 [Lactuca sativa]
          Length = 955

 Score =  761 bits (1966), Expect = 0.0
 Identities = 387/582 (66%), Positives = 434/582 (74%), Gaps = 2/582 (0%)
 Frame = +1

Query: 1    NDYHIISSRDHEKFQDLRHKGCNLLGPLCVFSCAKENRMLPKQGFTCCLAMDGVKILASG 180
            +DYHIISSRDHEKF DLR KGCNL+GP CVFSCAKENR+LPKQGFTCCLAMDGV IL SG
Sbjct: 50   DDYHIISSRDHEKFNDLRQKGCNLIGPQCVFSCAKENRVLPKQGFTCCLAMDGVNILTSG 109

Query: 181  FEMEAKVEIGKLVTAMGGMMLNKASSDVDFVIAKNVQAAKYKWALNTLKKPIVLESWLQL 360
            FE E K E+ KLVTAMGG++  KAS D++FVI KNV AAKYKWALN LKKPIV ESWL  
Sbjct: 110  FEKEGKDELDKLVTAMGGLLQTKASMDINFVIVKNVLAAKYKWALNALKKPIVSESWLHQ 169

Query: 361  CWKEHHVVPHESYRAPSFSRLKRSVTQVPPAERKEIEMLVIQNGGIYSAELTKKSTHLVC 540
            CWKEH VVPH+SYR   FS L  SVTQVP   RKEIE LVIQNGG YSAELT+KSTHLVC
Sbjct: 170  CWKEHRVVPHDSYRVLPFSGLTISVTQVPLDARKEIEKLVIQNGGKYSAELTRKSTHLVC 229

Query: 541  DAPEGDKYKVAKKWGHPHIVTRAWFNHSVARRACLNEESYPVQKGVATSANSHKNSLKA* 720
            DAPEGDKYKVAK+WGH  IVTR WF+ SVARRACLNE+SYPVQ+   TS NS + SLK  
Sbjct: 230  DAPEGDKYKVAKRWGHIRIVTRTWFDQSVARRACLNEDSYPVQRSPGTSMNSQRTSLKMQ 289

Query: 721  HNQNKVVRNSQCGPHSTTHQEISCDGVPDADVETTLSQNMASTISDISVPVSEDCTPPCI 900
            H+Q KV+RNSQ  P S THQEISCDG+ DAD+E TLSQNMAST SDI   +SE+ T P I
Sbjct: 290  HSQEKVIRNSQGAPISITHQEISCDGMADADLEATLSQNMASTCSDIPGIISEEKTTPTI 349

Query: 901  QPNNSMNIDNCVAEXXXXXXXXXXXXXCKIHIVGFDASEMRKLVNMVRRGGGSRYMSLNE 1080
            QP   M+ID CVAE             CKIH+VGFDA EMR+LVNMVRRG GSRYMSLN+
Sbjct: 350  QPKTCMDIDGCVAEDSQSEGNDLYFLNCKIHLVGFDAPEMRRLVNMVRRGSGSRYMSLND 409

Query: 1081 QLTHIVVGNPSESEKKEVRSLSAMGVINVVRTVWLEDCERQKKEVPVHRRHVAYDLLLPK 1260
            QLTHIVVG PSE+EKKEVRSLSAMGVINVV+TVWLEDCER+KKE+PV RRHVAYDLLLPK
Sbjct: 410  QLTHIVVGTPSETEKKEVRSLSAMGVINVVKTVWLEDCEREKKELPVLRRHVAYDLLLPK 469

Query: 1261 DTISSNKGSVSTMSGPKQGKPTSIQPTLPNNXXXXXXXXXXXXXXXXXXXXXE--IKXXX 1434
            D++  NKG VS + G KQG  +++QP L N+                     +   K   
Sbjct: 470  DSMPFNKGFVSAIPGLKQGNTSTVQPPLQNDQSQSQSLDKGQQKVQHGINNEKQNNKSSV 529

Query: 1435 XXXXXXXXXXXXPDVQRPEVVDWIQEGGGEVVDTQGVKNVDYTVESHGVLCNPAQFSGVT 1614
                        PDVQR E+VDWI EGGG+VVDT   KNV+YTVE+HGVLC+  QF+GVT
Sbjct: 530  FRGRSFRFSSTFPDVQRGEIVDWIHEGGGKVVDTLTEKNVNYTVEAHGVLCSRTQFNGVT 589

Query: 1615 NVSSHWIRSCLQDGHLLDISSHVSFLHFNAKFLYLGLLGFNY 1740
            NVSSHWIRSCLQDG LLD+SS++ F     K    G  G  +
Sbjct: 590  NVSSHWIRSCLQDGCLLDVSSYILFSPLQCKIPLPGFTGLQF 631



 Score =  143 bits (361), Expect = 1e-31
 Identities = 59/87 (67%), Positives = 77/87 (88%)
 Frame = +3

Query: 1683 LFSPLQCKVPLPGFIGLQLCVSQYEEKDRELLRSLCHVLGGRLNNKLTKKINYLVCKFSG 1862
            LFSPLQCK+PLPGF GLQ CVSQYE+K++ELLR++CHVLGG+L  +LTKK+NYL+CKF+ 
Sbjct: 613  LFSPLQCKIPLPGFTGLQFCVSQYEDKEKELLRNVCHVLGGKLVKRLTKKVNYLICKFTE 672

Query: 1863 GPKYEAACQWGMQSVTIEWIWECVKQD 1943
            GPK+EAA +WG+ +VT EW+WE + Q+
Sbjct: 673  GPKFEAAREWGVHTVTTEWLWESINQN 699


>ref|XP_023763387.1| DNA topoisomerase 2-binding protein 1 isoform X1 [Lactuca sativa]
 ref|XP_023763390.1| DNA topoisomerase 2-binding protein 1 isoform X1 [Lactuca sativa]
          Length = 956

 Score =  761 bits (1966), Expect = 0.0
 Identities = 387/582 (66%), Positives = 434/582 (74%), Gaps = 2/582 (0%)
 Frame = +1

Query: 1    NDYHIISSRDHEKFQDLRHKGCNLLGPLCVFSCAKENRMLPKQGFTCCLAMDGVKILASG 180
            +DYHIISSRDHEKF DLR KGCNL+GP CVFSCAKENR+LPKQGFTCCLAMDGV IL SG
Sbjct: 50   DDYHIISSRDHEKFNDLRQKGCNLIGPQCVFSCAKENRVLPKQGFTCCLAMDGVNILTSG 109

Query: 181  FEMEAKVEIGKLVTAMGGMMLNKASSDVDFVIAKNVQAAKYKWALNTLKKPIVLESWLQL 360
            FE E K E+ KLVTAMGG++  KAS D++FVI KNV AAKYKWALN LKKPIV ESWL  
Sbjct: 110  FEKEGKDELDKLVTAMGGLLQTKASMDINFVIVKNVLAAKYKWALNALKKPIVSESWLHQ 169

Query: 361  CWKEHHVVPHESYRAPSFSRLKRSVTQVPPAERKEIEMLVIQNGGIYSAELTKKSTHLVC 540
            CWKEH VVPH+SYR   FS L  SVTQVP   RKEIE LVIQNGG YSAELT+KSTHLVC
Sbjct: 170  CWKEHRVVPHDSYRVLPFSGLTISVTQVPLDARKEIEKLVIQNGGKYSAELTRKSTHLVC 229

Query: 541  DAPEGDKYKVAKKWGHPHIVTRAWFNHSVARRACLNEESYPVQKGVATSANSHKNSLKA* 720
            DAPEGDKYKVAK+WGH  IVTR WF+ SVARRACLNE+SYPVQ+   TS NS + SLK  
Sbjct: 230  DAPEGDKYKVAKRWGHIRIVTRTWFDQSVARRACLNEDSYPVQRSPGTSMNSQRTSLKMQ 289

Query: 721  HNQNKVVRNSQCGPHSTTHQEISCDGVPDADVETTLSQNMASTISDISVPVSEDCTPPCI 900
            H+Q KV+RNSQ  P S THQEISCDG+ DAD+E TLSQNMAST SDI   +SE+ T P I
Sbjct: 290  HSQEKVIRNSQGAPISITHQEISCDGMADADLEATLSQNMASTCSDIPGIISEEKTTPTI 349

Query: 901  QPNNSMNIDNCVAEXXXXXXXXXXXXXCKIHIVGFDASEMRKLVNMVRRGGGSRYMSLNE 1080
            QP   M+ID CVAE             CKIH+VGFDA EMR+LVNMVRRG GSRYMSLN+
Sbjct: 350  QPKTCMDIDGCVAEDSQSEGNDLYFLNCKIHLVGFDAPEMRRLVNMVRRGSGSRYMSLND 409

Query: 1081 QLTHIVVGNPSESEKKEVRSLSAMGVINVVRTVWLEDCERQKKEVPVHRRHVAYDLLLPK 1260
            QLTHIVVG PSE+EKKEVRSLSAMGVINVV+TVWLEDCER+KKE+PV RRHVAYDLLLPK
Sbjct: 410  QLTHIVVGTPSETEKKEVRSLSAMGVINVVKTVWLEDCEREKKELPVLRRHVAYDLLLPK 469

Query: 1261 DTISSNKGSVSTMSGPKQGKPTSIQPTLPNNXXXXXXXXXXXXXXXXXXXXXE--IKXXX 1434
            D++  NKG VS + G KQG  +++QP L N+                     +   K   
Sbjct: 470  DSMPFNKGFVSAIPGLKQGNTSTVQPPLQNDQSQSQSLDKGQQKVQHGINNEKQNNKSSV 529

Query: 1435 XXXXXXXXXXXXPDVQRPEVVDWIQEGGGEVVDTQGVKNVDYTVESHGVLCNPAQFSGVT 1614
                        PDVQR E+VDWI EGGG+VVDT   KNV+YTVE+HGVLC+  QF+GVT
Sbjct: 530  FRGRSFRFSSTFPDVQRGEIVDWIHEGGGKVVDTLTEKNVNYTVEAHGVLCSRTQFNGVT 589

Query: 1615 NVSSHWIRSCLQDGHLLDISSHVSFLHFNAKFLYLGLLGFNY 1740
            NVSSHWIRSCLQDG LLD+SS++ F     K    G  G  +
Sbjct: 590  NVSSHWIRSCLQDGCLLDVSSYILFSPLQCKIPLPGFTGLQF 631



 Score =  143 bits (361), Expect = 1e-31
 Identities = 59/87 (67%), Positives = 77/87 (88%)
 Frame = +3

Query: 1683 LFSPLQCKVPLPGFIGLQLCVSQYEEKDRELLRSLCHVLGGRLNNKLTKKINYLVCKFSG 1862
            LFSPLQCK+PLPGF GLQ CVSQYE+K++ELLR++CHVLGG+L  +LTKK+NYL+CKF+ 
Sbjct: 613  LFSPLQCKIPLPGFTGLQFCVSQYEDKEKELLRNVCHVLGGKLVKRLTKKVNYLICKFTE 672

Query: 1863 GPKYEAACQWGMQSVTIEWIWECVKQD 1943
            GPK+EAA +WG+ +VT EW+WE + Q+
Sbjct: 673  GPKFEAAREWGVHTVTTEWLWESINQN 699


>ref|XP_023763415.1| DNA topoisomerase 2-binding protein 1 isoform X5 [Lactuca sativa]
          Length = 931

 Score =  739 bits (1909), Expect = 0.0
 Identities = 377/571 (66%), Positives = 423/571 (74%), Gaps = 2/571 (0%)
 Frame = +1

Query: 34   EKFQDLRHKGCNLLGPLCVFSCAKENRMLPKQGFTCCLAMDGVKILASGFEMEAKVEIGK 213
            EKF DLR KGCNL+GP CVFSCAKENR+LPKQGFTCCLAMDGV IL SGFE E K E+ K
Sbjct: 36   EKFNDLRQKGCNLIGPQCVFSCAKENRVLPKQGFTCCLAMDGVNILTSGFEKEGKDELDK 95

Query: 214  LVTAMGGMMLNKASSDVDFVIAKNVQAAKYKWALNTLKKPIVLESWLQLCWKEHHVVPHE 393
            LVTAMGG++  KAS D++FVI KNV AAKYKWALN LKKPIV ESWL  CWKEH VVPH+
Sbjct: 96   LVTAMGGLLQTKASMDINFVIVKNVLAAKYKWALNALKKPIVSESWLHQCWKEHRVVPHD 155

Query: 394  SYRAPSFSRLKRSVTQVPPAERKEIEMLVIQNGGIYSAELTKKSTHLVCDAPEGDKYKVA 573
            SYR   FS L  SVTQVP   RKEIE LVIQNGG YSAELT+KSTHLVCDAPEGDKYKVA
Sbjct: 156  SYRVLPFSGLTISVTQVPLDARKEIEKLVIQNGGKYSAELTRKSTHLVCDAPEGDKYKVA 215

Query: 574  KKWGHPHIVTRAWFNHSVARRACLNEESYPVQKGVATSANSHKNSLKA*HNQNKVVRNSQ 753
            K+WGH  IVTR WF+ SVARRACLNE+SYPVQ+   TS NS + SLK  H+Q KV+RNSQ
Sbjct: 216  KRWGHIRIVTRTWFDQSVARRACLNEDSYPVQRSPGTSMNSQRTSLKMQHSQEKVIRNSQ 275

Query: 754  CGPHSTTHQEISCDGVPDADVETTLSQNMASTISDISVPVSEDCTPPCIQPNNSMNIDNC 933
              P S THQEISCDG+ DAD+E TLSQNMAST SDI   +SE+ T P IQP   M+ID C
Sbjct: 276  GAPISITHQEISCDGMADADLEATLSQNMASTCSDIPGIISEEKTTPTIQPKTCMDIDGC 335

Query: 934  VAEXXXXXXXXXXXXXCKIHIVGFDASEMRKLVNMVRRGGGSRYMSLNEQLTHIVVGNPS 1113
            VAE             CKIH+VGFDA EMR+LVNMVRRG GSRYMSLN+QLTHIVVG PS
Sbjct: 336  VAEDSQSEGNDLYFLNCKIHLVGFDAPEMRRLVNMVRRGSGSRYMSLNDQLTHIVVGTPS 395

Query: 1114 ESEKKEVRSLSAMGVINVVRTVWLEDCERQKKEVPVHRRHVAYDLLLPKDTISSNKGSVS 1293
            E+EKKEVRSLSAMGVINVV+TVWLEDCER+KKE+PV RRHVAYDLLLPKD++  NKG VS
Sbjct: 396  ETEKKEVRSLSAMGVINVVKTVWLEDCEREKKELPVLRRHVAYDLLLPKDSMPFNKGFVS 455

Query: 1294 TMSGPKQGKPTSIQPTLPNNXXXXXXXXXXXXXXXXXXXXXE--IKXXXXXXXXXXXXXX 1467
             + G KQG  +++QP L N+                     +   K              
Sbjct: 456  AIPGLKQGNTSTVQPPLQNDQSQSQSLDKGQQKVQHGINNEKQNNKSSVFRGRSFRFSST 515

Query: 1468 XPDVQRPEVVDWIQEGGGEVVDTQGVKNVDYTVESHGVLCNPAQFSGVTNVSSHWIRSCL 1647
             PDVQR E+VDWI EGGG+VVDT   KNV+YTVE+HGVLC+  QF+GVTNVSSHWIRSCL
Sbjct: 516  FPDVQRGEIVDWIHEGGGKVVDTLTEKNVNYTVEAHGVLCSRTQFNGVTNVSSHWIRSCL 575

Query: 1648 QDGHLLDISSHVSFLHFNAKFLYLGLLGFNY 1740
            QDG LLD+SS++ F     K    G  G  +
Sbjct: 576  QDGCLLDVSSYILFSPLQCKIPLPGFTGLQF 606



 Score =  143 bits (361), Expect = 1e-31
 Identities = 59/87 (67%), Positives = 77/87 (88%)
 Frame = +3

Query: 1683 LFSPLQCKVPLPGFIGLQLCVSQYEEKDRELLRSLCHVLGGRLNNKLTKKINYLVCKFSG 1862
            LFSPLQCK+PLPGF GLQ CVSQYE+K++ELLR++CHVLGG+L  +LTKK+NYL+CKF+ 
Sbjct: 588  LFSPLQCKIPLPGFTGLQFCVSQYEDKEKELLRNVCHVLGGKLVKRLTKKVNYLICKFTE 647

Query: 1863 GPKYEAACQWGMQSVTIEWIWECVKQD 1943
            GPK+EAA +WG+ +VT EW+WE + Q+
Sbjct: 648  GPKFEAAREWGVHTVTTEWLWESINQN 674


>gb|OTG33974.1| putative transcription coactivator [Helianthus annuus]
          Length = 978

 Score =  727 bits (1877), Expect = 0.0
 Identities = 391/633 (61%), Positives = 432/633 (68%), Gaps = 53/633 (8%)
 Frame = +1

Query: 1    NDYHIISSRDHEKFQDLRHKGCNLLG---------------------------PLCVFSC 99
            ND+HIISSRDHEKF DLR KGCNLLG                           P CVFSC
Sbjct: 49   NDFHIISSRDHEKFNDLRQKGCNLLGMAVSLSSQYGVFQLSCFFVPKYSNLVRPQCVFSC 108

Query: 100  AKENRMLPKQGFTCCLAMDGVKILASGFEMEAKVEIGKLVTAMGGMMLNKASSDVDFVIA 279
            AKENR+LPKQGFTCCLAMDGVKILASGFEM+ K EIGKLVTAMGG++  KASSDV FVI 
Sbjct: 109  AKENRVLPKQGFTCCLAMDGVKILASGFEMKEKDEIGKLVTAMGGVLQTKASSDVSFVIV 168

Query: 280  KNVQAAKYKWALNTLKKPIVLESWLQLCWKEHHVVPHESYRAPSFSRLKRSVTQVPPA-- 453
            KNV AAKYKWALN LKKPIV +SWL  CWKEH VV HE YR   FS L  SVTQVP    
Sbjct: 169  KNVLAAKYKWALNNLKKPIVSDSWLHRCWKEHRVVSHEPYRTLPFSGLTISVTQVPLGLL 228

Query: 454  ----------------------ERKEIEMLVIQNGGIYSAELTKKSTHLVCDAPEGDKYK 567
                                  ERKEIE LV QNGG YSAELT+KSTHLVCD     KYK
Sbjct: 229  AYFMNIGKYVFMSLLMCFFIIDERKEIEKLVQQNGGKYSAELTRKSTHLVCD-----KYK 283

Query: 568  VAKKWGHPHIVTRAWFNHSVARRACLNEESYPVQKGVATSANSHKNSLKA*HNQNKVVRN 747
            VAK+WGH HIV+R WFN SVARRACLNEESYPVQK   TS NS + S       +KVV+N
Sbjct: 284  VAKRWGHIHIVSRTWFNQSVARRACLNEESYPVQKTSVTSTNSQRTS-------SKVVKN 336

Query: 748  SQCGPHSTTHQEISCDGVPDADVETTLSQNMASTISDISVPVSED--CTPPCIQPNNSMN 921
            ++     +++QEISCDG+ DAD+E TLSQNMASTISDI VPVS+D   TPPC+Q   S N
Sbjct: 337  AE----GSSYQEISCDGMVDADLEATLSQNMASTISDIPVPVSDDNTSTPPCVQHKTSFN 392

Query: 922  IDNCVAEXXXXXXXXXXXXXCKIHIVGFDASEMRKLVNMVRRGGGSRYMSLNEQLTHIVV 1101
            ID CVAE             CKIH+VGFDASEMR+LVNMVRRGGGSRYMSLNEQLTHIVV
Sbjct: 393  IDACVAEDSQSEDNDLYLLNCKIHLVGFDASEMRRLVNMVRRGGGSRYMSLNEQLTHIVV 452

Query: 1102 GNPSESEKKEVRSLSAMGVINVVRTVWLEDCERQKKEVPVHRRHVAYDLLLPKDTISSNK 1281
            G+PSESEKKEVRSLSAMGVINVV+TVWLEDCER+KKE+ V RRH AYDLLLPKD+IS NK
Sbjct: 453  GSPSESEKKEVRSLSAMGVINVVKTVWLEDCEREKKEISVLRRHAAYDLLLPKDSISYNK 512

Query: 1282 GSVSTMSGPKQGKPTSIQPTLPNNXXXXXXXXXXXXXXXXXXXXXEIKXXXXXXXXXXXX 1461
            GSV+ + G KQG P++IQP   N+                     E K            
Sbjct: 513  GSVNGIPGLKQGNPSTIQPAFSNDLSKSLSEGRQRTQHVISNKSQEKKSSVFIGRSFRFS 572

Query: 1462 XXXPDVQRPEVVDWIQEGGGEVVDTQGVKNVDYTVESHGVLCNPAQFSGVTNVSSHWIRS 1641
               PDVQR E+VDWI EGGGEVVD+Q  K VDYTVE+HGVLC P Q +G TNVS HWIRS
Sbjct: 573  SSFPDVQRGEIVDWIHEGGGEVVDSQTKKIVDYTVEAHGVLCRPTQLTGATNVSPHWIRS 632

Query: 1642 CLQDGHLLDISSHVSFLHFNAKFLYLGLLGFNY 1740
            CLQDGHLLD+ SH+ F     K    G +G  +
Sbjct: 633  CLQDGHLLDVRSHLLFSPLQCKVPLPGFIGLQF 665



 Score =  172 bits (437), Expect = 5e-41
 Identities = 77/87 (88%), Positives = 83/87 (95%)
 Frame = +3

Query: 1683 LFSPLQCKVPLPGFIGLQLCVSQYEEKDRELLRSLCHVLGGRLNNKLTKKINYLVCKFSG 1862
            LFSPLQCKVPLPGFIGLQ CVSQYEEKDRELLR+LCHVLGG+L  KLTKK+NYL+CKFS 
Sbjct: 647  LFSPLQCKVPLPGFIGLQFCVSQYEEKDRELLRNLCHVLGGKLIKKLTKKVNYLICKFSE 706

Query: 1863 GPKYEAACQWGMQSVTIEWIWECVKQD 1943
            GPKYEAACQWGMQ+VTIEWIWECVKQ+
Sbjct: 707  GPKYEAACQWGMQTVTIEWIWECVKQN 733


>ref|XP_022016130.1| DNA topoisomerase 2-binding protein 1 isoform X3 [Helianthus annuus]
 ref|XP_022016137.1| DNA topoisomerase 2-binding protein 1 isoform X3 [Helianthus annuus]
          Length = 835

 Score =  673 bits (1736), Expect = 0.0
 Identities = 351/532 (65%), Positives = 390/532 (73%), Gaps = 2/532 (0%)
 Frame = +1

Query: 151  MDGVKILASGFEMEAKVEIGKLVTAMGGMMLNKASSDVDFVIAKNVQAAKYKWALNTLKK 330
            MDGVKILASGFEM+ K EIGKLVTAMGG++  KASSDV FVI KNV AAKYKWALN LKK
Sbjct: 1    MDGVKILASGFEMKEKDEIGKLVTAMGGVLQTKASSDVSFVIVKNVLAAKYKWALNNLKK 60

Query: 331  PIVLESWLQLCWKEHHVVPHESYRAPSFSRLKRSVTQVPPAERKEIEMLVIQNGGIYSAE 510
            PIV +SWL  CWKEH VV HE YR   FS L  SVTQVP  ERKEIE LV QNGG YSAE
Sbjct: 61   PIVSDSWLHRCWKEHRVVSHEPYRTLPFSGLTISVTQVPLDERKEIEKLVQQNGGKYSAE 120

Query: 511  LTKKSTHLVCDAPEGDKYKVAKKWGHPHIVTRAWFNHSVARRACLNEESYPVQKGVATSA 690
            LT+KSTHLVCDAPEGDKYKVAK+WGH HIV+R WFN SVARRACLNEESYPVQK   TS 
Sbjct: 121  LTRKSTHLVCDAPEGDKYKVAKRWGHIHIVSRTWFNQSVARRACLNEESYPVQKTSVTST 180

Query: 691  NSHKNSLKA*HNQNKVVRNSQCGPHSTTHQEISCDGVPDADVETTLSQNMASTISDISVP 870
            NS + S       +KVV+N++     +++QEISCDG+ DAD+E TLSQNMASTISDI VP
Sbjct: 181  NSQRTS-------SKVVKNAE----GSSYQEISCDGMVDADLEATLSQNMASTISDIPVP 229

Query: 871  VSED--CTPPCIQPNNSMNIDNCVAEXXXXXXXXXXXXXCKIHIVGFDASEMRKLVNMVR 1044
            VS+D   TPPC+Q   S NID CVAE             CKIH+VGFDASEMR+LVNMVR
Sbjct: 230  VSDDNTSTPPCVQHKTSFNIDACVAEDSQSEDNDLYLLNCKIHLVGFDASEMRRLVNMVR 289

Query: 1045 RGGGSRYMSLNEQLTHIVVGNPSESEKKEVRSLSAMGVINVVRTVWLEDCERQKKEVPVH 1224
            RGGGSRYMSLNEQLTHIVVG+PSESEKKEVRSLSAMGVINVV+TVWLEDCER+KKE+ V 
Sbjct: 290  RGGGSRYMSLNEQLTHIVVGSPSESEKKEVRSLSAMGVINVVKTVWLEDCEREKKEISVL 349

Query: 1225 RRHVAYDLLLPKDTISSNKGSVSTMSGPKQGKPTSIQPTLPNNXXXXXXXXXXXXXXXXX 1404
            RRH AYDLLLPKD+IS NKGSV+ + G KQG P++IQP   N+                 
Sbjct: 350  RRHAAYDLLLPKDSISYNKGSVNGIPGLKQGNPSTIQPAFSNDLSKSLSEGRQRTQHVIS 409

Query: 1405 XXXXEIKXXXXXXXXXXXXXXXPDVQRPEVVDWIQEGGGEVVDTQGVKNVDYTVESHGVL 1584
                E K               PDVQR E+VDWI EGGGEVVD+Q  K VDYTVE+HGVL
Sbjct: 410  NKSQEKKSSVFIGRSFRFSSSFPDVQRGEIVDWIHEGGGEVVDSQTKKIVDYTVEAHGVL 469

Query: 1585 CNPAQFSGVTNVSSHWIRSCLQDGHLLDISSHVSFLHFNAKFLYLGLLGFNY 1740
            C P Q +G TNVS HWIRSCLQDGHLLD+ SH+ F     K    G +G  +
Sbjct: 470  CRPTQLTGATNVSPHWIRSCLQDGHLLDVRSHLLFSPLQCKVPLPGFIGLQF 521



 Score =  172 bits (437), Expect = 3e-41
 Identities = 77/87 (88%), Positives = 83/87 (95%)
 Frame = +3

Query: 1683 LFSPLQCKVPLPGFIGLQLCVSQYEEKDRELLRSLCHVLGGRLNNKLTKKINYLVCKFSG 1862
            LFSPLQCKVPLPGFIGLQ CVSQYEEKDRELLR+LCHVLGG+L  KLTKK+NYL+CKFS 
Sbjct: 503  LFSPLQCKVPLPGFIGLQFCVSQYEEKDRELLRNLCHVLGGKLIKKLTKKVNYLICKFSE 562

Query: 1863 GPKYEAACQWGMQSVTIEWIWECVKQD 1943
            GPKYEAACQWGMQ+VTIEWIWECVKQ+
Sbjct: 563  GPKYEAACQWGMQTVTIEWIWECVKQN 589


>ref|XP_023763423.1| DNA topoisomerase 2-binding protein 1 isoform X6 [Lactuca sativa]
          Length = 857

 Score =  664 bits (1713), Expect = 0.0
 Identities = 343/532 (64%), Positives = 387/532 (72%), Gaps = 2/532 (0%)
 Frame = +1

Query: 151  MDGVKILASGFEMEAKVEIGKLVTAMGGMMLNKASSDVDFVIAKNVQAAKYKWALNTLKK 330
            MDGV IL SGFE E K E+ KLVTAMGG++  KAS D++FVI KNV AAKYKWALN LKK
Sbjct: 1    MDGVNILTSGFEKEGKDELDKLVTAMGGLLQTKASMDINFVIVKNVLAAKYKWALNALKK 60

Query: 331  PIVLESWLQLCWKEHHVVPHESYRAPSFSRLKRSVTQVPPAERKEIEMLVIQNGGIYSAE 510
            PIV ESWL  CWKEH VVPH+SYR   FS L  SVTQVP   RKEIE LVIQNGG YSAE
Sbjct: 61   PIVSESWLHQCWKEHRVVPHDSYRVLPFSGLTISVTQVPLDARKEIEKLVIQNGGKYSAE 120

Query: 511  LTKKSTHLVCDAPEGDKYKVAKKWGHPHIVTRAWFNHSVARRACLNEESYPVQKGVATSA 690
            LT+KSTHLVCDAPEGDKYKVAK+WGH  IVTR WF+ SVARRACLNE+SYPVQ+   TS 
Sbjct: 121  LTRKSTHLVCDAPEGDKYKVAKRWGHIRIVTRTWFDQSVARRACLNEDSYPVQRSPGTSM 180

Query: 691  NSHKNSLKA*HNQNKVVRNSQCGPHSTTHQEISCDGVPDADVETTLSQNMASTISDISVP 870
            NS + SLK  H+Q KV+RNSQ  P S THQEISCDG+ DAD+E TLSQNMAST SDI   
Sbjct: 181  NSQRTSLKMQHSQEKVIRNSQGAPISITHQEISCDGMADADLEATLSQNMASTCSDIPGI 240

Query: 871  VSEDCTPPCIQPNNSMNIDNCVAEXXXXXXXXXXXXXCKIHIVGFDASEMRKLVNMVRRG 1050
            +SE+ T P IQP   M+ID CVAE             CKIH+VGFDA EMR+LVNMVRRG
Sbjct: 241  ISEEKTTPTIQPKTCMDIDGCVAEDSQSEGNDLYFLNCKIHLVGFDAPEMRRLVNMVRRG 300

Query: 1051 GGSRYMSLNEQLTHIVVGNPSESEKKEVRSLSAMGVINVVRTVWLEDCERQKKEVPVHRR 1230
             GSRYMSLN+QLTHIVVG PSE+EKKEVRSLSAMGVINVV+TVWLEDCER+KKE+PV RR
Sbjct: 301  SGSRYMSLNDQLTHIVVGTPSETEKKEVRSLSAMGVINVVKTVWLEDCEREKKELPVLRR 360

Query: 1231 HVAYDLLLPKDTISSNKGSVSTMSGPKQGKPTSIQPTLPNNXXXXXXXXXXXXXXXXXXX 1410
            HVAYDLLLPKD++  NKG VS + G KQG  +++QP L N+                   
Sbjct: 361  HVAYDLLLPKDSMPFNKGFVSAIPGLKQGNTSTVQPPLQNDQSQSQSLDKGQQKVQHGIN 420

Query: 1411 XXE--IKXXXXXXXXXXXXXXXPDVQRPEVVDWIQEGGGEVVDTQGVKNVDYTVESHGVL 1584
              +   K               PDVQR E+VDWI EGGG+VVDT   KNV+YTVE+HGVL
Sbjct: 421  NEKQNNKSSVFRGRSFRFSSTFPDVQRGEIVDWIHEGGGKVVDTLTEKNVNYTVEAHGVL 480

Query: 1585 CNPAQFSGVTNVSSHWIRSCLQDGHLLDISSHVSFLHFNAKFLYLGLLGFNY 1740
            C+  QF+GVTNVSSHWIRSCLQDG LLD+SS++ F     K    G  G  +
Sbjct: 481  CSRTQFNGVTNVSSHWIRSCLQDGCLLDVSSYILFSPLQCKIPLPGFTGLQF 532



 Score =  143 bits (361), Expect = 1e-31
 Identities = 59/87 (67%), Positives = 77/87 (88%)
 Frame = +3

Query: 1683 LFSPLQCKVPLPGFIGLQLCVSQYEEKDRELLRSLCHVLGGRLNNKLTKKINYLVCKFSG 1862
            LFSPLQCK+PLPGF GLQ CVSQYE+K++ELLR++CHVLGG+L  +LTKK+NYL+CKF+ 
Sbjct: 514  LFSPLQCKIPLPGFTGLQFCVSQYEDKEKELLRNVCHVLGGKLVKRLTKKVNYLICKFTE 573

Query: 1863 GPKYEAACQWGMQSVTIEWIWECVKQD 1943
            GPK+EAA +WG+ +VT EW+WE + Q+
Sbjct: 574  GPKFEAAREWGVHTVTTEWLWESINQN 600


>ref|XP_017981837.1| PREDICTED: DNA topoisomerase 2-binding protein 1-A [Theobroma cacao]
          Length = 979

 Score =  598 bits (1543), Expect = 0.0
 Identities = 322/630 (51%), Positives = 395/630 (62%), Gaps = 50/630 (7%)
 Frame = +1

Query: 1    NDYHIISSRDHEKFQDLRHKGCNLLGPLCVFSCAKENRMLPKQGFTCCLAMDGVKILASG 180
            +D+H+ISS DHEKF+DLR KGCNLLGP CV SCAKENR LPKQGFTCCLAMDG+K+LASG
Sbjct: 52   DDFHVISSIDHEKFEDLRAKGCNLLGPQCVLSCAKENRALPKQGFTCCLAMDGLKVLASG 111

Query: 181  FEMEAKVEIGKLVTAMGGMMLNKASSDVDFVIAKNVQAAKYKWALNTLKKPIVLESWLQL 360
            F+M+ KV+I KLVTAMGG++  KAS DV FV+ KNV AAKYKWALN LKKPIV   WL  
Sbjct: 112  FDMDEKVKIEKLVTAMGGVLHTKASLDVSFVVVKNVLAAKYKWALNVLKKPIVTLHWLYQ 171

Query: 361  CWKEHHVVPHESYRAPSFSRLKRSVTQVPPAERKEIEMLVIQNGGIYSAELTKKSTHLVC 540
            CW EH VVP ESYR   FS L   VT++P  ERKEIE L+IQNGG YSAELTKK THL+C
Sbjct: 172  CWGEHRVVPQESYRVLPFSGLTICVTRIPADERKEIEKLIIQNGGKYSAELTKKCTHLIC 231

Query: 541  DAPEGDKYKVAKKWGHPHIVTRAWFNHSVARRACLNEESYPVQKGVATSANSHKNSLKA* 720
            DAPEGDKYKVA++WGH HIV R WF+ S+ARRACLNEESYPVQ G ++S  S   SL   
Sbjct: 232  DAPEGDKYKVARRWGHVHIVVRKWFDQSIARRACLNEESYPVQGGCSSSKKSVSGSLSTQ 291

Query: 721  HNQNKVVRNSQCGPHSTTHQEISCDGVP-----DADVETTLSQNMASTISDISVPVSEDC 885
            H+Q+K  R S     S+   E +   VP     D D+E TLSQN+ S +SD  V V ED 
Sbjct: 292  HSQDKF-RGSSLSATSSMISEFNLSTVPPTGVGDPDLEATLSQNIPSMVSDAQVIVKEDG 350

Query: 886  -TPPCIQPNNSMNIDNCVAEXXXXXXXXXXXXXCKIHIVGFDASEMRKLVNMVRRGGGSR 1062
               P +QP+N   +D CVA              C+I +VGF+ASEMRKLV MVRRGGGSR
Sbjct: 351  GEAPTLQPSNETKLDGCVANDSESEDNDLYLSDCRISLVGFEASEMRKLVMMVRRGGGSR 410

Query: 1063 YMSLNEQLTHIVVGNPSESEKKEVRSLSAMGVINVVRTVWLEDCERQKKEVPVHRRHVAY 1242
            YMS N++LTHIVVG PSE EKKEVRS +A GV++VV++ WLEDC+RQKKE+PV +RH+AY
Sbjct: 411  YMSCNDKLTHIVVGTPSEVEKKEVRSFAASGVMHVVKSNWLEDCDRQKKEIPVQQRHIAY 470

Query: 1243 DLLLPKDTISS-------------NKGSVSTMSGP------------------------- 1308
            DLLLPKD++ S             +K SV   SG                          
Sbjct: 471  DLLLPKDSVQSVKGAVIGMVSSNQSKSSVLANSGTGMSSFLGDNLDDKTKINRNGDKSLE 530

Query: 1309 ------KQGKPTSIQPTLPNNXXXXXXXXXXXXXXXXXXXXXEIKXXXXXXXXXXXXXXX 1470
                  KQG P ++  T  NN                       K               
Sbjct: 531  ATVRSSKQGVPPTVNST--NNGWQKQHCGSIVLNLKNGMSSTVFKGKLFCFSNSF----- 583

Query: 1471 PDVQRPEVVDWIQEGGGEVVDTQGVKNVDYTVESHGVLCNPAQFSGVTNVSSHWIRSCLQ 1650
            P+ +R E+V+W+ +GGGEVVD    ++V++ +E HGV+      S +T VS+HW+RSCL+
Sbjct: 584  PEDRRAEIVEWVDQGGGEVVDDHVKQSVNFIIECHGVISRSIIDSQITYVSTHWVRSCLE 643

Query: 1651 DGHLLDISSHVSFLHFNAKFLYLGLLGFNY 1740
            DG LLD+  H+ +     +  + G   F +
Sbjct: 644  DGCLLDVGCHILYSPLPCQIPFPGFKSFRF 673



 Score =  130 bits (327), Expect = 2e-27
 Identities = 58/95 (61%), Positives = 72/95 (75%), Gaps = 6/95 (6%)
 Frame = +3

Query: 1683 LFSPLQCKVPLPGFIGLQLCVSQYEEKDRELLRSLCHVLGGRLNNKLTKKINYLVCKFSG 1862
            L+SPL C++P PGF   + CVSQYEEKDR LLR+LC +LG +   KLTKK+ +L+CKF+ 
Sbjct: 655  LYSPLPCQIPFPGFKSFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFTS 714

Query: 1863 GPKYEAACQWGMQSVTIEWIWECVKQ------DPF 1949
            GPKYEAAC+WG+ SVT EWI+ECV Q      DPF
Sbjct: 715  GPKYEAACKWGIYSVTAEWIYECVSQNKVVSLDPF 749


>gb|EOY16438.1| Topbp1, putative isoform 5 [Theobroma cacao]
          Length = 894

 Score =  595 bits (1534), Expect = 0.0
 Identities = 320/630 (50%), Positives = 393/630 (62%), Gaps = 50/630 (7%)
 Frame = +1

Query: 1    NDYHIISSRDHEKFQDLRHKGCNLLGPLCVFSCAKENRMLPKQGFTCCLAMDGVKILASG 180
            +D+H+ISS DHEKF+DLR KGCNLLGP CV SCAKENR LPKQGFTCCLAMDG+K+LASG
Sbjct: 52   DDFHVISSIDHEKFEDLRAKGCNLLGPQCVLSCAKENRALPKQGFTCCLAMDGLKVLASG 111

Query: 181  FEMEAKVEIGKLVTAMGGMMLNKASSDVDFVIAKNVQAAKYKWALNTLKKPIVLESWLQL 360
            F+M+ KV+I KLVTAMGG++  KAS DV FV+ KNV AAKYKWALN LKKPIV   WL  
Sbjct: 112  FDMDEKVKIEKLVTAMGGVLHTKASLDVSFVVVKNVLAAKYKWALNVLKKPIVTLHWLYQ 171

Query: 361  CWKEHHVVPHESYRAPSFSRLKRSVTQVPPAERKEIEMLVIQNGGIYSAELTKKSTHLVC 540
            CW EH VVP ESYR   FS L   VT++P  ERKEIE L+IQNGG YSAELTKK THL+C
Sbjct: 172  CWGEHRVVPQESYRVLPFSGLTICVTRIPADERKEIEKLIIQNGGKYSAELTKKCTHLIC 231

Query: 541  DAPEGDKYKVAKKWGHPHIVTRAWFNHSVARRACLNEESYPVQKGVATSANSHKNSLKA* 720
            DAPEGDKYKVA++WGH HIV R WF+ S+ARRACLNEESYPVQ G ++S  +   SL   
Sbjct: 232  DAPEGDKYKVARRWGHVHIVVRKWFDQSIARRACLNEESYPVQGGCSSSKKNVSGSLSTQ 291

Query: 721  HNQNKVVRNSQCGPHSTTHQEISCDGVP-----DADVETTLSQNMASTISDISVPVSEDC 885
            H+Q+K  R S     S    + +   VP     D D+E TLSQN+ S +SD  V V ED 
Sbjct: 292  HSQDKF-RGSSLSATSLMISDFNLSTVPPTGVGDPDLEATLSQNIPSMVSDAQVIVKEDG 350

Query: 886  -TPPCIQPNNSMNIDNCVAEXXXXXXXXXXXXXCKIHIVGFDASEMRKLVNMVRRGGGSR 1062
               P +QP+N   +D CVA              C+I +VGF+ASEMRKLV MVRRGGGSR
Sbjct: 351  GEAPTLQPSNETKLDGCVANDSESEDNDLYLSDCRISLVGFEASEMRKLVMMVRRGGGSR 410

Query: 1063 YMSLNEQLTHIVVGNPSESEKKEVRSLSAMGVINVVRTVWLEDCERQKKEVPVHRRHVAY 1242
            YMS N++LTHIVVG PSE EKKEVRS +A GV+ VV++ WLEDC+RQKKE+PV +RH+AY
Sbjct: 411  YMSCNDKLTHIVVGTPSEVEKKEVRSFAASGVMQVVKSNWLEDCDRQKKEIPVQQRHIAY 470

Query: 1243 DLLLPKDTISS-------------NKGSVSTMSGP------------------------- 1308
            DLLLPKD++ S             +K SV   SG                          
Sbjct: 471  DLLLPKDSVQSVKGAVIGMVSSNQSKSSVLANSGTGMSSFLGDNLDDKTKINRNGDKSLE 530

Query: 1309 ------KQGKPTSIQPTLPNNXXXXXXXXXXXXXXXXXXXXXEIKXXXXXXXXXXXXXXX 1470
                  KQG P ++  T  NN                       K               
Sbjct: 531  ATVRSSKQGVPPTVNST--NNGWQKQHCGSIVLNLKNGMSSTVFKGKIFCFSNSF----- 583

Query: 1471 PDVQRPEVVDWIQEGGGEVVDTQGVKNVDYTVESHGVLCNPAQFSGVTNVSSHWIRSCLQ 1650
            P+ +R E+V+W+ +GGGEVVD    ++V++ +E HGV+      S +T VS+HW+RSCL+
Sbjct: 584  PEDRRAEIVEWVDQGGGEVVDDHVKQSVNFIIECHGVISRSIIDSQITYVSTHWVRSCLE 643

Query: 1651 DGHLLDISSHVSFLHFNAKFLYLGLLGFNY 1740
            DG LLD+  H+ +     +  + G   F +
Sbjct: 644  DGCLLDVGCHILYSPLPCQIPFPGFKSFRF 673



 Score =  130 bits (327), Expect = 2e-27
 Identities = 58/95 (61%), Positives = 72/95 (75%), Gaps = 6/95 (6%)
 Frame = +3

Query: 1683 LFSPLQCKVPLPGFIGLQLCVSQYEEKDRELLRSLCHVLGGRLNNKLTKKINYLVCKFSG 1862
            L+SPL C++P PGF   + CVSQYEEKDR LLR+LC +LG +   KLTKK+ +L+CKF+ 
Sbjct: 655  LYSPLPCQIPFPGFKSFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFTS 714

Query: 1863 GPKYEAACQWGMQSVTIEWIWECVKQ------DPF 1949
            GPKYEAAC+WG+ SVT EWI+ECV Q      DPF
Sbjct: 715  GPKYEAACKWGIYSVTAEWIYECVSQNKVVSLDPF 749


>gb|EOY16436.1| Topbp1, putative isoform 3 [Theobroma cacao]
          Length = 929

 Score =  595 bits (1534), Expect = 0.0
 Identities = 320/630 (50%), Positives = 393/630 (62%), Gaps = 50/630 (7%)
 Frame = +1

Query: 1    NDYHIISSRDHEKFQDLRHKGCNLLGPLCVFSCAKENRMLPKQGFTCCLAMDGVKILASG 180
            +D+H+ISS DHEKF+DLR KGCNLLGP CV SCAKENR LPKQGFTCCLAMDG+K+LASG
Sbjct: 52   DDFHVISSIDHEKFEDLRAKGCNLLGPQCVLSCAKENRALPKQGFTCCLAMDGLKVLASG 111

Query: 181  FEMEAKVEIGKLVTAMGGMMLNKASSDVDFVIAKNVQAAKYKWALNTLKKPIVLESWLQL 360
            F+M+ KV+I KLVTAMGG++  KAS DV FV+ KNV AAKYKWALN LKKPIV   WL  
Sbjct: 112  FDMDEKVKIEKLVTAMGGVLHTKASLDVSFVVVKNVLAAKYKWALNVLKKPIVTLHWLYQ 171

Query: 361  CWKEHHVVPHESYRAPSFSRLKRSVTQVPPAERKEIEMLVIQNGGIYSAELTKKSTHLVC 540
            CW EH VVP ESYR   FS L   VT++P  ERKEIE L+IQNGG YSAELTKK THL+C
Sbjct: 172  CWGEHRVVPQESYRVLPFSGLTICVTRIPADERKEIEKLIIQNGGKYSAELTKKCTHLIC 231

Query: 541  DAPEGDKYKVAKKWGHPHIVTRAWFNHSVARRACLNEESYPVQKGVATSANSHKNSLKA* 720
            DAPEGDKYKVA++WGH HIV R WF+ S+ARRACLNEESYPVQ G ++S  +   SL   
Sbjct: 232  DAPEGDKYKVARRWGHVHIVVRKWFDQSIARRACLNEESYPVQGGCSSSKKNVSGSLSTQ 291

Query: 721  HNQNKVVRNSQCGPHSTTHQEISCDGVP-----DADVETTLSQNMASTISDISVPVSEDC 885
            H+Q+K  R S     S    + +   VP     D D+E TLSQN+ S +SD  V V ED 
Sbjct: 292  HSQDKF-RGSSLSATSLMISDFNLSTVPPTGVGDPDLEATLSQNIPSMVSDAQVIVKEDG 350

Query: 886  -TPPCIQPNNSMNIDNCVAEXXXXXXXXXXXXXCKIHIVGFDASEMRKLVNMVRRGGGSR 1062
               P +QP+N   +D CVA              C+I +VGF+ASEMRKLV MVRRGGGSR
Sbjct: 351  GEAPTLQPSNETKLDGCVANDSESEDNDLYLSDCRISLVGFEASEMRKLVMMVRRGGGSR 410

Query: 1063 YMSLNEQLTHIVVGNPSESEKKEVRSLSAMGVINVVRTVWLEDCERQKKEVPVHRRHVAY 1242
            YMS N++LTHIVVG PSE EKKEVRS +A GV+ VV++ WLEDC+RQKKE+PV +RH+AY
Sbjct: 411  YMSCNDKLTHIVVGTPSEVEKKEVRSFAASGVMQVVKSNWLEDCDRQKKEIPVQQRHIAY 470

Query: 1243 DLLLPKDTISS-------------NKGSVSTMSGP------------------------- 1308
            DLLLPKD++ S             +K SV   SG                          
Sbjct: 471  DLLLPKDSVQSVKGAVIGMVSSNQSKSSVLANSGTGMSSFLGDNLDDKTKINRNGDKSLE 530

Query: 1309 ------KQGKPTSIQPTLPNNXXXXXXXXXXXXXXXXXXXXXEIKXXXXXXXXXXXXXXX 1470
                  KQG P ++  T  NN                       K               
Sbjct: 531  ATVRSSKQGVPPTVNST--NNGWQKQHCGSIVLNLKNGMSSTVFKGKIFCFSNSF----- 583

Query: 1471 PDVQRPEVVDWIQEGGGEVVDTQGVKNVDYTVESHGVLCNPAQFSGVTNVSSHWIRSCLQ 1650
            P+ +R E+V+W+ +GGGEVVD    ++V++ +E HGV+      S +T VS+HW+RSCL+
Sbjct: 584  PEDRRAEIVEWVDQGGGEVVDDHVKQSVNFIIECHGVISRSIIDSQITYVSTHWVRSCLE 643

Query: 1651 DGHLLDISSHVSFLHFNAKFLYLGLLGFNY 1740
            DG LLD+  H+ +     +  + G   F +
Sbjct: 644  DGCLLDVGCHILYSPLPCQIPFPGFKSFRF 673



 Score =  130 bits (327), Expect = 2e-27
 Identities = 58/95 (61%), Positives = 72/95 (75%), Gaps = 6/95 (6%)
 Frame = +3

Query: 1683 LFSPLQCKVPLPGFIGLQLCVSQYEEKDRELLRSLCHVLGGRLNNKLTKKINYLVCKFSG 1862
            L+SPL C++P PGF   + CVSQYEEKDR LLR+LC +LG +   KLTKK+ +L+CKF+ 
Sbjct: 655  LYSPLPCQIPFPGFKSFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFTS 714

Query: 1863 GPKYEAACQWGMQSVTIEWIWECVKQ------DPF 1949
            GPKYEAAC+WG+ SVT EWI+ECV Q      DPF
Sbjct: 715  GPKYEAACKWGIYSVTAEWIYECVSQNKVVSLDPF 749


>gb|EOY16437.1| Topbp1, putative isoform 4 [Theobroma cacao]
          Length = 971

 Score =  595 bits (1534), Expect = 0.0
 Identities = 320/630 (50%), Positives = 393/630 (62%), Gaps = 50/630 (7%)
 Frame = +1

Query: 1    NDYHIISSRDHEKFQDLRHKGCNLLGPLCVFSCAKENRMLPKQGFTCCLAMDGVKILASG 180
            +D+H+ISS DHEKF+DLR KGCNLLGP CV SCAKENR LPKQGFTCCLAMDG+K+LASG
Sbjct: 52   DDFHVISSIDHEKFEDLRAKGCNLLGPQCVLSCAKENRALPKQGFTCCLAMDGLKVLASG 111

Query: 181  FEMEAKVEIGKLVTAMGGMMLNKASSDVDFVIAKNVQAAKYKWALNTLKKPIVLESWLQL 360
            F+M+ KV+I KLVTAMGG++  KAS DV FV+ KNV AAKYKWALN LKKPIV   WL  
Sbjct: 112  FDMDEKVKIEKLVTAMGGVLHTKASLDVSFVVVKNVLAAKYKWALNVLKKPIVTLHWLYQ 171

Query: 361  CWKEHHVVPHESYRAPSFSRLKRSVTQVPPAERKEIEMLVIQNGGIYSAELTKKSTHLVC 540
            CW EH VVP ESYR   FS L   VT++P  ERKEIE L+IQNGG YSAELTKK THL+C
Sbjct: 172  CWGEHRVVPQESYRVLPFSGLTICVTRIPADERKEIEKLIIQNGGKYSAELTKKCTHLIC 231

Query: 541  DAPEGDKYKVAKKWGHPHIVTRAWFNHSVARRACLNEESYPVQKGVATSANSHKNSLKA* 720
            DAPEGDKYKVA++WGH HIV R WF+ S+ARRACLNEESYPVQ G ++S  +   SL   
Sbjct: 232  DAPEGDKYKVARRWGHVHIVVRKWFDQSIARRACLNEESYPVQGGCSSSKKNVSGSLSTQ 291

Query: 721  HNQNKVVRNSQCGPHSTTHQEISCDGVP-----DADVETTLSQNMASTISDISVPVSEDC 885
            H+Q+K  R S     S    + +   VP     D D+E TLSQN+ S +SD  V V ED 
Sbjct: 292  HSQDKF-RGSSLSATSLMISDFNLSTVPPTGVGDPDLEATLSQNIPSMVSDAQVIVKEDG 350

Query: 886  -TPPCIQPNNSMNIDNCVAEXXXXXXXXXXXXXCKIHIVGFDASEMRKLVNMVRRGGGSR 1062
               P +QP+N   +D CVA              C+I +VGF+ASEMRKLV MVRRGGGSR
Sbjct: 351  GEAPTLQPSNETKLDGCVANDSESEDNDLYLSDCRISLVGFEASEMRKLVMMVRRGGGSR 410

Query: 1063 YMSLNEQLTHIVVGNPSESEKKEVRSLSAMGVINVVRTVWLEDCERQKKEVPVHRRHVAY 1242
            YMS N++LTHIVVG PSE EKKEVRS +A GV+ VV++ WLEDC+RQKKE+PV +RH+AY
Sbjct: 411  YMSCNDKLTHIVVGTPSEVEKKEVRSFAASGVMQVVKSNWLEDCDRQKKEIPVQQRHIAY 470

Query: 1243 DLLLPKDTISS-------------NKGSVSTMSGP------------------------- 1308
            DLLLPKD++ S             +K SV   SG                          
Sbjct: 471  DLLLPKDSVQSVKGAVIGMVSSNQSKSSVLANSGTGMSSFLGDNLDDKTKINRNGDKSLE 530

Query: 1309 ------KQGKPTSIQPTLPNNXXXXXXXXXXXXXXXXXXXXXEIKXXXXXXXXXXXXXXX 1470
                  KQG P ++  T  NN                       K               
Sbjct: 531  ATVRSSKQGVPPTVNST--NNGWQKQHCGSIVLNLKNGMSSTVFKGKIFCFSNSF----- 583

Query: 1471 PDVQRPEVVDWIQEGGGEVVDTQGVKNVDYTVESHGVLCNPAQFSGVTNVSSHWIRSCLQ 1650
            P+ +R E+V+W+ +GGGEVVD    ++V++ +E HGV+      S +T VS+HW+RSCL+
Sbjct: 584  PEDRRAEIVEWVDQGGGEVVDDHVKQSVNFIIECHGVISRSIIDSQITYVSTHWVRSCLE 643

Query: 1651 DGHLLDISSHVSFLHFNAKFLYLGLLGFNY 1740
            DG LLD+  H+ +     +  + G   F +
Sbjct: 644  DGCLLDVGCHILYSPLPCQIPFPGFKSFRF 673



 Score =  130 bits (327), Expect = 2e-27
 Identities = 58/95 (61%), Positives = 72/95 (75%), Gaps = 6/95 (6%)
 Frame = +3

Query: 1683 LFSPLQCKVPLPGFIGLQLCVSQYEEKDRELLRSLCHVLGGRLNNKLTKKINYLVCKFSG 1862
            L+SPL C++P PGF   + CVSQYEEKDR LLR+LC +LG +   KLTKK+ +L+CKF+ 
Sbjct: 655  LYSPLPCQIPFPGFKSFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFTS 714

Query: 1863 GPKYEAACQWGMQSVTIEWIWECVKQ------DPF 1949
            GPKYEAAC+WG+ SVT EWI+ECV Q      DPF
Sbjct: 715  GPKYEAACKWGIYSVTAEWIYECVSQNKVVSLDPF 749


>gb|EOY16434.1| Topbp1, putative isoform 1 [Theobroma cacao]
          Length = 979

 Score =  595 bits (1534), Expect = 0.0
 Identities = 320/630 (50%), Positives = 393/630 (62%), Gaps = 50/630 (7%)
 Frame = +1

Query: 1    NDYHIISSRDHEKFQDLRHKGCNLLGPLCVFSCAKENRMLPKQGFTCCLAMDGVKILASG 180
            +D+H+ISS DHEKF+DLR KGCNLLGP CV SCAKENR LPKQGFTCCLAMDG+K+LASG
Sbjct: 52   DDFHVISSIDHEKFEDLRAKGCNLLGPQCVLSCAKENRALPKQGFTCCLAMDGLKVLASG 111

Query: 181  FEMEAKVEIGKLVTAMGGMMLNKASSDVDFVIAKNVQAAKYKWALNTLKKPIVLESWLQL 360
            F+M+ KV+I KLVTAMGG++  KAS DV FV+ KNV AAKYKWALN LKKPIV   WL  
Sbjct: 112  FDMDEKVKIEKLVTAMGGVLHTKASLDVSFVVVKNVLAAKYKWALNVLKKPIVTLHWLYQ 171

Query: 361  CWKEHHVVPHESYRAPSFSRLKRSVTQVPPAERKEIEMLVIQNGGIYSAELTKKSTHLVC 540
            CW EH VVP ESYR   FS L   VT++P  ERKEIE L+IQNGG YSAELTKK THL+C
Sbjct: 172  CWGEHRVVPQESYRVLPFSGLTICVTRIPADERKEIEKLIIQNGGKYSAELTKKCTHLIC 231

Query: 541  DAPEGDKYKVAKKWGHPHIVTRAWFNHSVARRACLNEESYPVQKGVATSANSHKNSLKA* 720
            DAPEGDKYKVA++WGH HIV R WF+ S+ARRACLNEESYPVQ G ++S  +   SL   
Sbjct: 232  DAPEGDKYKVARRWGHVHIVVRKWFDQSIARRACLNEESYPVQGGCSSSKKNVSGSLSTQ 291

Query: 721  HNQNKVVRNSQCGPHSTTHQEISCDGVP-----DADVETTLSQNMASTISDISVPVSEDC 885
            H+Q+K  R S     S    + +   VP     D D+E TLSQN+ S +SD  V V ED 
Sbjct: 292  HSQDKF-RGSSLSATSLMISDFNLSTVPPTGVGDPDLEATLSQNIPSMVSDAQVIVKEDG 350

Query: 886  -TPPCIQPNNSMNIDNCVAEXXXXXXXXXXXXXCKIHIVGFDASEMRKLVNMVRRGGGSR 1062
               P +QP+N   +D CVA              C+I +VGF+ASEMRKLV MVRRGGGSR
Sbjct: 351  GEAPTLQPSNETKLDGCVANDSESEDNDLYLSDCRISLVGFEASEMRKLVMMVRRGGGSR 410

Query: 1063 YMSLNEQLTHIVVGNPSESEKKEVRSLSAMGVINVVRTVWLEDCERQKKEVPVHRRHVAY 1242
            YMS N++LTHIVVG PSE EKKEVRS +A GV+ VV++ WLEDC+RQKKE+PV +RH+AY
Sbjct: 411  YMSCNDKLTHIVVGTPSEVEKKEVRSFAASGVMQVVKSNWLEDCDRQKKEIPVQQRHIAY 470

Query: 1243 DLLLPKDTISS-------------NKGSVSTMSGP------------------------- 1308
            DLLLPKD++ S             +K SV   SG                          
Sbjct: 471  DLLLPKDSVQSVKGAVIGMVSSNQSKSSVLANSGTGMSSFLGDNLDDKTKINRNGDKSLE 530

Query: 1309 ------KQGKPTSIQPTLPNNXXXXXXXXXXXXXXXXXXXXXEIKXXXXXXXXXXXXXXX 1470
                  KQG P ++  T  NN                       K               
Sbjct: 531  ATVRSSKQGVPPTVNST--NNGWQKQHCGSIVLNLKNGMSSTVFKGKIFCFSNSF----- 583

Query: 1471 PDVQRPEVVDWIQEGGGEVVDTQGVKNVDYTVESHGVLCNPAQFSGVTNVSSHWIRSCLQ 1650
            P+ +R E+V+W+ +GGGEVVD    ++V++ +E HGV+      S +T VS+HW+RSCL+
Sbjct: 584  PEDRRAEIVEWVDQGGGEVVDDHVKQSVNFIIECHGVISRSIIDSQITYVSTHWVRSCLE 643

Query: 1651 DGHLLDISSHVSFLHFNAKFLYLGLLGFNY 1740
            DG LLD+  H+ +     +  + G   F +
Sbjct: 644  DGCLLDVGCHILYSPLPCQIPFPGFKSFRF 673



 Score =  130 bits (327), Expect = 2e-27
 Identities = 58/95 (61%), Positives = 72/95 (75%), Gaps = 6/95 (6%)
 Frame = +3

Query: 1683 LFSPLQCKVPLPGFIGLQLCVSQYEEKDRELLRSLCHVLGGRLNNKLTKKINYLVCKFSG 1862
            L+SPL C++P PGF   + CVSQYEEKDR LLR+LC +LG +   KLTKK+ +L+CKF+ 
Sbjct: 655  LYSPLPCQIPFPGFKSFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFTS 714

Query: 1863 GPKYEAACQWGMQSVTIEWIWECVKQ------DPF 1949
            GPKYEAAC+WG+ SVT EWI+ECV Q      DPF
Sbjct: 715  GPKYEAACKWGIYSVTAEWIYECVSQNKVVSLDPF 749


>gb|EOY16435.1| Topbp1, putative isoform 2 [Theobroma cacao]
          Length = 980

 Score =  595 bits (1534), Expect = 0.0
 Identities = 320/630 (50%), Positives = 393/630 (62%), Gaps = 50/630 (7%)
 Frame = +1

Query: 1    NDYHIISSRDHEKFQDLRHKGCNLLGPLCVFSCAKENRMLPKQGFTCCLAMDGVKILASG 180
            +D+H+ISS DHEKF+DLR KGCNLLGP CV SCAKENR LPKQGFTCCLAMDG+K+LASG
Sbjct: 52   DDFHVISSIDHEKFEDLRAKGCNLLGPQCVLSCAKENRALPKQGFTCCLAMDGLKVLASG 111

Query: 181  FEMEAKVEIGKLVTAMGGMMLNKASSDVDFVIAKNVQAAKYKWALNTLKKPIVLESWLQL 360
            F+M+ KV+I KLVTAMGG++  KAS DV FV+ KNV AAKYKWALN LKKPIV   WL  
Sbjct: 112  FDMDEKVKIEKLVTAMGGVLHTKASLDVSFVVVKNVLAAKYKWALNVLKKPIVTLHWLYQ 171

Query: 361  CWKEHHVVPHESYRAPSFSRLKRSVTQVPPAERKEIEMLVIQNGGIYSAELTKKSTHLVC 540
            CW EH VVP ESYR   FS L   VT++P  ERKEIE L+IQNGG YSAELTKK THL+C
Sbjct: 172  CWGEHRVVPQESYRVLPFSGLTICVTRIPADERKEIEKLIIQNGGKYSAELTKKCTHLIC 231

Query: 541  DAPEGDKYKVAKKWGHPHIVTRAWFNHSVARRACLNEESYPVQKGVATSANSHKNSLKA* 720
            DAPEGDKYKVA++WGH HIV R WF+ S+ARRACLNEESYPVQ G ++S  +   SL   
Sbjct: 232  DAPEGDKYKVARRWGHVHIVVRKWFDQSIARRACLNEESYPVQGGCSSSKKNVSGSLSTQ 291

Query: 721  HNQNKVVRNSQCGPHSTTHQEISCDGVP-----DADVETTLSQNMASTISDISVPVSEDC 885
            H+Q+K  R S     S    + +   VP     D D+E TLSQN+ S +SD  V V ED 
Sbjct: 292  HSQDKF-RGSSLSATSLMISDFNLSTVPPTGVGDPDLEATLSQNIPSMVSDAQVIVKEDG 350

Query: 886  -TPPCIQPNNSMNIDNCVAEXXXXXXXXXXXXXCKIHIVGFDASEMRKLVNMVRRGGGSR 1062
               P +QP+N   +D CVA              C+I +VGF+ASEMRKLV MVRRGGGSR
Sbjct: 351  GEAPTLQPSNETKLDGCVANDSESEDNDLYLSDCRISLVGFEASEMRKLVMMVRRGGGSR 410

Query: 1063 YMSLNEQLTHIVVGNPSESEKKEVRSLSAMGVINVVRTVWLEDCERQKKEVPVHRRHVAY 1242
            YMS N++LTHIVVG PSE EKKEVRS +A GV+ VV++ WLEDC+RQKKE+PV +RH+AY
Sbjct: 411  YMSCNDKLTHIVVGTPSEVEKKEVRSFAASGVMQVVKSNWLEDCDRQKKEIPVQQRHIAY 470

Query: 1243 DLLLPKDTISS-------------NKGSVSTMSGP------------------------- 1308
            DLLLPKD++ S             +K SV   SG                          
Sbjct: 471  DLLLPKDSVQSVKGAVIGMVSSNQSKSSVLANSGTGMSSFLGDNLDDKTKINRNGDKSLE 530

Query: 1309 ------KQGKPTSIQPTLPNNXXXXXXXXXXXXXXXXXXXXXEIKXXXXXXXXXXXXXXX 1470
                  KQG P ++  T  NN                       K               
Sbjct: 531  ATVRSSKQGVPPTVNST--NNGWQKQHCGSIVLNLKNGMSSTVFKGKIFCFSNSF----- 583

Query: 1471 PDVQRPEVVDWIQEGGGEVVDTQGVKNVDYTVESHGVLCNPAQFSGVTNVSSHWIRSCLQ 1650
            P+ +R E+V+W+ +GGGEVVD    ++V++ +E HGV+      S +T VS+HW+RSCL+
Sbjct: 584  PEDRRAEIVEWVDQGGGEVVDDHVKQSVNFIIECHGVISRSIIDSQITYVSTHWVRSCLE 643

Query: 1651 DGHLLDISSHVSFLHFNAKFLYLGLLGFNY 1740
            DG LLD+  H+ +     +  + G   F +
Sbjct: 644  DGCLLDVGCHILYSPLPCQIPFPGFKSFRF 673



 Score =  130 bits (327), Expect = 2e-27
 Identities = 58/95 (61%), Positives = 72/95 (75%), Gaps = 6/95 (6%)
 Frame = +3

Query: 1683 LFSPLQCKVPLPGFIGLQLCVSQYEEKDRELLRSLCHVLGGRLNNKLTKKINYLVCKFSG 1862
            L+SPL C++P PGF   + CVSQYEEKDR LLR+LC +LG +   KLTKK+ +L+CKF+ 
Sbjct: 655  LYSPLPCQIPFPGFKSFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFTS 714

Query: 1863 GPKYEAACQWGMQSVTIEWIWECVKQ------DPF 1949
            GPKYEAAC+WG+ SVT EWI+ECV Q      DPF
Sbjct: 715  GPKYEAACKWGIYSVTAEWIYECVSQNKVVSLDPF 749


>ref|XP_016685711.1| PREDICTED: DNA topoisomerase 2-binding protein 1-like isoform X3
            [Gossypium hirsutum]
          Length = 826

 Score =  585 bits (1507), Expect = 0.0
 Identities = 314/623 (50%), Positives = 385/623 (61%), Gaps = 43/623 (6%)
 Frame = +1

Query: 1    NDYHIISSRDHEKFQDLRHKGCNLLGPLCVFSCAKENRMLPKQGFTCCLAMDGVKILASG 180
            +D+H+ISS DHEKF+DLR KGCNL+GP CV SCA ENR LP+QGF+CCLAMDG+K+LASG
Sbjct: 53   DDFHVISSFDHEKFEDLRTKGCNLIGPQCVISCANENRALPQQGFSCCLAMDGLKVLASG 112

Query: 181  FEMEAKVEIGKLVTAMGGMMLNKASSDVDFVIAKNVQAAKYKWALNTLKKPIVLESWLQL 360
            F+M+ KV+I KLV AMGG++  KAS DV FVI KNV AAKYKWALN LKKPIV   WL  
Sbjct: 113  FDMDEKVKIEKLVIAMGGVLHTKASLDVSFVIVKNVLAAKYKWALNVLKKPIVTIQWLYQ 172

Query: 361  CWKEHHVVPHESYRAPSFSRLKRSVTQVPPAERKEIEMLVIQNGGIYSAELTKKSTHLVC 540
            CW EH VVP ESYR   F+ L  SVT +   ERKEIE L+IQNGG YSAELTKK THL+C
Sbjct: 173  CWSEHRVVPQESYRVLPFTGLTISVTGIRADERKEIEKLIIQNGGKYSAELTKKCTHLIC 232

Query: 541  DAPEGDKYKVAKKWGHPHIVTRAWFNHSVARRACLNEESYPVQKGVATSANSHKNSLKA* 720
            D PEGDKYKVA++WGH HI+ R WF+  +ARRACLNEESYPVQ G A+S  S   SL A 
Sbjct: 233  DVPEGDKYKVARRWGHVHIIVRKWFDQCIARRACLNEESYPVQGGSASSKKSVSGSLSAQ 292

Query: 721  HNQNKVVRNSQCGPHSTTHQEISCDGVP-----DADVETTLSQNMASTISDISVPVSEDC 885
            H+Q+K  R S     S    E +   VP     D D+E   SQN  S +SD      ED 
Sbjct: 293  HSQDKF-RASSVSATSLVVPEFNMSTVPSTGLGDPDLEAAHSQNTPSVLSDAQAIFEEDG 351

Query: 886  -TPPCIQPNNSMNIDNCVAEXXXXXXXXXXXXXCKIHIVGFDASEMRKLVNMVRRGGGSR 1062
               P ++P+    +D CVA              CKI +VGF+ASEMRKLV MVRRGG SR
Sbjct: 352  GEAPNLKPSTETKLDGCVANDSQSEDNDLYLSDCKISLVGFEASEMRKLVTMVRRGGASR 411

Query: 1063 YMSLNEQLTHIVVGNPSESEKKEVRSLSAMGVINVVRTVWLEDCERQKKEVPVHRRHVAY 1242
            YMS NE+LTHIVVG PSE EKKEVRS++A GVI+VV+T WLEDC+RQKKE+PVH+RHVAY
Sbjct: 412  YMSCNEKLTHIVVGAPSELEKKEVRSIAASGVIHVVKTSWLEDCDRQKKEIPVHQRHVAY 471

Query: 1243 DLLLPKDT-----------ISSNKGSVSTMSGPKQGKPTSI------------------- 1332
            DLLLPKD+           I+SN+   S  +    G P+S                    
Sbjct: 472  DLLLPKDSAHSVRGAVTGIINSNQSKSSVPTNSGTGMPSSFGKSLDDKPKINMNGGSCLK 531

Query: 1333 -------QPTLPNNXXXXXXXXXXXXXXXXXXXXXEIKXXXXXXXXXXXXXXXPDVQRPE 1491
                   Q  LP                        I                P+ +R E
Sbjct: 532  ATVGSSKQGLLPTINSTSNFWQKQQSDSVVQNPKNGISSAVFKGKTFCFSVSFPEDRRAE 591

Query: 1492 VVDWIQEGGGEVVDTQGVKNVDYTVESHGVLCNPAQFSGVTNVSSHWIRSCLQDGHLLDI 1671
            +V+W+ +GGG+VV+ Q  KNV++ +E HGV+ +    S +T VS+HW+RSCL+DG LLD+
Sbjct: 592  IVEWVDQGGGQVVEDQVKKNVNFIIECHGVIPSCIADSQITYVSTHWVRSCLEDGCLLDV 651

Query: 1672 SSHVSFLHFNAKFLYLGLLGFNY 1740
             SH+ +     +  + G   F +
Sbjct: 652  GSHILYSPLPCQIPFPGFKNFRF 674



 Score =  129 bits (325), Expect = 3e-27
 Identities = 54/86 (62%), Positives = 71/86 (82%)
 Frame = +3

Query: 1683 LFSPLQCKVPLPGFIGLQLCVSQYEEKDRELLRSLCHVLGGRLNNKLTKKINYLVCKFSG 1862
            L+SPL C++P PGF   + CVSQYEEKDR LLR+LC +LG +   KLTKK+ +L+CKF+ 
Sbjct: 656  LYSPLPCQIPFPGFKNFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFTS 715

Query: 1863 GPKYEAACQWGMQSVTIEWIWECVKQ 1940
            GPKYEAAC+WG++SVT EWI+EC++Q
Sbjct: 716  GPKYEAACKWGIRSVTSEWIYECLRQ 741


>ref|XP_016685710.1| PREDICTED: DNA topoisomerase 2-binding protein 1-A-like isoform X2
            [Gossypium hirsutum]
          Length = 937

 Score =  585 bits (1507), Expect = 0.0
 Identities = 314/623 (50%), Positives = 385/623 (61%), Gaps = 43/623 (6%)
 Frame = +1

Query: 1    NDYHIISSRDHEKFQDLRHKGCNLLGPLCVFSCAKENRMLPKQGFTCCLAMDGVKILASG 180
            +D+H+ISS DHEKF+DLR KGCNL+GP CV SCA ENR LP+QGF+CCLAMDG+K+LASG
Sbjct: 53   DDFHVISSFDHEKFEDLRTKGCNLIGPQCVISCANENRALPQQGFSCCLAMDGLKVLASG 112

Query: 181  FEMEAKVEIGKLVTAMGGMMLNKASSDVDFVIAKNVQAAKYKWALNTLKKPIVLESWLQL 360
            F+M+ KV+I KLV AMGG++  KAS DV FVI KNV AAKYKWALN LKKPIV   WL  
Sbjct: 113  FDMDEKVKIEKLVIAMGGVLHTKASLDVSFVIVKNVLAAKYKWALNVLKKPIVTIQWLYQ 172

Query: 361  CWKEHHVVPHESYRAPSFSRLKRSVTQVPPAERKEIEMLVIQNGGIYSAELTKKSTHLVC 540
            CW EH VVP ESYR   F+ L  SVT +   ERKEIE L+IQNGG YSAELTKK THL+C
Sbjct: 173  CWSEHRVVPQESYRVLPFTGLTISVTGIRADERKEIEKLIIQNGGKYSAELTKKCTHLIC 232

Query: 541  DAPEGDKYKVAKKWGHPHIVTRAWFNHSVARRACLNEESYPVQKGVATSANSHKNSLKA* 720
            D PEGDKYKVA++WGH HI+ R WF+  +ARRACLNEESYPVQ G A+S  S   SL A 
Sbjct: 233  DVPEGDKYKVARRWGHVHIIVRKWFDQCIARRACLNEESYPVQGGSASSKKSVSGSLSAQ 292

Query: 721  HNQNKVVRNSQCGPHSTTHQEISCDGVP-----DADVETTLSQNMASTISDISVPVSEDC 885
            H+Q+K  R S     S    E +   VP     D D+E   SQN  S +SD      ED 
Sbjct: 293  HSQDKF-RASSVSATSLVVPEFNMSTVPSTGLGDPDLEAAHSQNTPSVLSDAQAIFEEDG 351

Query: 886  -TPPCIQPNNSMNIDNCVAEXXXXXXXXXXXXXCKIHIVGFDASEMRKLVNMVRRGGGSR 1062
               P ++P+    +D CVA              CKI +VGF+ASEMRKLV MVRRGG SR
Sbjct: 352  GEAPNLKPSTETKLDGCVANDSQSEDNDLYLSDCKISLVGFEASEMRKLVTMVRRGGASR 411

Query: 1063 YMSLNEQLTHIVVGNPSESEKKEVRSLSAMGVINVVRTVWLEDCERQKKEVPVHRRHVAY 1242
            YMS NE+LTHIVVG PSE EKKEVRS++A GVI+VV+T WLEDC+RQKKE+PVH+RHVAY
Sbjct: 412  YMSCNEKLTHIVVGAPSELEKKEVRSIAASGVIHVVKTSWLEDCDRQKKEIPVHQRHVAY 471

Query: 1243 DLLLPKDT-----------ISSNKGSVSTMSGPKQGKPTSI------------------- 1332
            DLLLPKD+           I+SN+   S  +    G P+S                    
Sbjct: 472  DLLLPKDSAHSVRGAVTGIINSNQSKSSVPTNSGTGMPSSFGKSLDDKPKINMNGGSCLK 531

Query: 1333 -------QPTLPNNXXXXXXXXXXXXXXXXXXXXXEIKXXXXXXXXXXXXXXXPDVQRPE 1491
                   Q  LP                        I                P+ +R E
Sbjct: 532  ATVGSSKQGLLPTINSTSNFWQKQQSDSVVQNPKNGISSAVFKGKTFCFSVSFPEDRRAE 591

Query: 1492 VVDWIQEGGGEVVDTQGVKNVDYTVESHGVLCNPAQFSGVTNVSSHWIRSCLQDGHLLDI 1671
            +V+W+ +GGG+VV+ Q  KNV++ +E HGV+ +    S +T VS+HW+RSCL+DG LLD+
Sbjct: 592  IVEWVDQGGGQVVEDQVKKNVNFIIECHGVIPSCIADSQITYVSTHWVRSCLEDGCLLDV 651

Query: 1672 SSHVSFLHFNAKFLYLGLLGFNY 1740
             SH+ +     +  + G   F +
Sbjct: 652  GSHILYSPLPCQIPFPGFKNFRF 674



 Score =  130 bits (327), Expect = 2e-27
 Identities = 57/95 (60%), Positives = 74/95 (77%), Gaps = 6/95 (6%)
 Frame = +3

Query: 1683 LFSPLQCKVPLPGFIGLQLCVSQYEEKDRELLRSLCHVLGGRLNNKLTKKINYLVCKFSG 1862
            L+SPL C++P PGF   + CVSQYEEKDR LLR+LC +LG +   KLTKK+ +L+CKF+ 
Sbjct: 656  LYSPLPCQIPFPGFKNFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFTS 715

Query: 1863 GPKYEAACQWGMQSVTIEWIWECVKQ------DPF 1949
            GPKYEAAC+WG++SVT EWI+EC++Q      DPF
Sbjct: 716  GPKYEAACKWGIRSVTSEWIYECLRQNKVVSLDPF 750


>ref|XP_012464227.1| PREDICTED: DNA topoisomerase 2-binding protein 1-A isoform X2
            [Gossypium raimondii]
          Length = 937

 Score =  583 bits (1503), Expect = 0.0
 Identities = 314/623 (50%), Positives = 383/623 (61%), Gaps = 43/623 (6%)
 Frame = +1

Query: 1    NDYHIISSRDHEKFQDLRHKGCNLLGPLCVFSCAKENRMLPKQGFTCCLAMDGVKILASG 180
            +D+H+ISS DHEKF+DLR KGCNL+GP CV SCA ENR LPKQGF+CCLAMDG+K+LASG
Sbjct: 53   DDFHVISSFDHEKFEDLRAKGCNLIGPQCVISCANENRALPKQGFSCCLAMDGLKVLASG 112

Query: 181  FEMEAKVEIGKLVTAMGGMMLNKASSDVDFVIAKNVQAAKYKWALNTLKKPIVLESWLQL 360
            F+M+ KV+I KLV AMGG++  KAS DV FVI KNV AAKYKWALN LKKPIV   WL  
Sbjct: 113  FDMDEKVKIEKLVIAMGGVLHTKASLDVSFVIVKNVLAAKYKWALNVLKKPIVTIQWLYQ 172

Query: 361  CWKEHHVVPHESYRAPSFSRLKRSVTQVPPAERKEIEMLVIQNGGIYSAELTKKSTHLVC 540
            CW EH VVP ESYR   F+ L  SVT +   ERKEIE L+IQNGG YSAELTKK THL+C
Sbjct: 173  CWSEHRVVPQESYRVLPFTGLTISVTGIRADERKEIEKLIIQNGGKYSAELTKKCTHLIC 232

Query: 541  DAPEGDKYKVAKKWGHPHIVTRAWFNHSVARRACLNEESYPVQKGVATSANSHKNSLKA* 720
            D PEGDKYKVA++WGH HI+ R WF+  +ARRACLNEESYPVQ G A+S  S   SL A 
Sbjct: 233  DVPEGDKYKVARRWGHVHIIVRKWFDQCIARRACLNEESYPVQGGSASSKKSVSGSLSAQ 292

Query: 721  HNQNKVVRNSQCGPHSTTHQEISCDGVP-----DADVETTLSQNMASTISDISVPVSEDC 885
            H+Q+K  R S     S    E +   VP     D D+E   SQN  S +SD      ED 
Sbjct: 293  HSQDKF-RASSVSATSLVVPEFNMSTVPSTGLGDPDLEAAHSQNTPSVLSDAQAIFEEDG 351

Query: 886  -TPPCIQPNNSMNIDNCVAEXXXXXXXXXXXXXCKIHIVGFDASEMRKLVNMVRRGGGSR 1062
               P +QP+    +D CVA              CKI +VGF+ASEMRKLV MVRRGG SR
Sbjct: 352  GEAPNLQPSTETKLDGCVANDSQSEDNDLYLSDCKISLVGFEASEMRKLVTMVRRGGASR 411

Query: 1063 YMSLNEQLTHIVVGNPSESEKKEVRSLSAMGVINVVRTVWLEDCERQKKEVPVHRRHVAY 1242
            YMS NE+LTHIVVG PSE EKKEVRS++A GVI+VV+T WLEDC+RQKKE+PVH+RHVAY
Sbjct: 412  YMSCNEKLTHIVVGAPSELEKKEVRSIAASGVIHVVKTSWLEDCDRQKKEIPVHQRHVAY 471

Query: 1243 DLLLPKDT-----------ISSNKGSVSTMSGPKQGKPTSI------------------- 1332
             LLLPKD+           I+SN+   S  +    G P+S                    
Sbjct: 472  GLLLPKDSAHSVRGAVTGIINSNQSKSSVPTNSGTGMPSSFGKSLDDKPKINMNGGSCLK 531

Query: 1333 -------QPTLPNNXXXXXXXXXXXXXXXXXXXXXEIKXXXXXXXXXXXXXXXPDVQRPE 1491
                   Q  LP                        I                P+ +R E
Sbjct: 532  ATVGSSKQGLLPTINSTSNFWQKQQYDSVVQNPKNGISSAVFKGKTFCFSVSFPEDRRAE 591

Query: 1492 VVDWIQEGGGEVVDTQGVKNVDYTVESHGVLCNPAQFSGVTNVSSHWIRSCLQDGHLLDI 1671
            +V+W+ +GGG+VV+ Q  KNV++ +E HGV+ +    S +T VS+HW+RSCL+DG LLD+
Sbjct: 592  IVEWVDQGGGQVVEDQVKKNVNFIIECHGVIPSCITDSQITYVSTHWVRSCLEDGCLLDV 651

Query: 1672 SSHVSFLHFNAKFLYLGLLGFNY 1740
              H+ +     +  + G   F +
Sbjct: 652  GRHILYSPLPCQIPFPGFKNFRF 674



 Score =  133 bits (334), Expect = 3e-28
 Identities = 59/95 (62%), Positives = 74/95 (77%), Gaps = 6/95 (6%)
 Frame = +3

Query: 1683 LFSPLQCKVPLPGFIGLQLCVSQYEEKDRELLRSLCHVLGGRLNNKLTKKINYLVCKFSG 1862
            L+SPL C++P PGF   + CVSQYEEKDR LLR+LC +LG +   KLTKK+ +L+CKF+ 
Sbjct: 656  LYSPLPCQIPFPGFKNFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFTS 715

Query: 1863 GPKYEAACQWGMQSVTIEWIWECVKQ------DPF 1949
            GPKYEAAC+WG+QSVT EWI+ECV+Q      DPF
Sbjct: 716  GPKYEAACKWGIQSVTSEWIYECVRQNKVVSLDPF 750