BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Chrysanthemum22_contig00012486
         (1144 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_021977342.1| DNA topoisomerase 2-like [Helianthus annuus]...   239   2e-66
ref|XP_023759895.1| DNA topoisomerase 2 [Lactuca sativa]              238   3e-66
ref|XP_022005320.1| DNA topoisomerase 2-like [Helianthus annuus]...   236   1e-65
gb|PLY88472.1| hypothetical protein LSAT_1X105720 [Lactuca sativa]    236   1e-65
ref|XP_015881654.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Z...   226   4e-62
ref|XP_015881653.1| PREDICTED: DNA topoisomerase 2 isoform X1 [Z...   226   4e-62
gb|PON46642.1| DNA topoisomerase II-type [Trema orientalis]           225   7e-62
gb|PON74229.1| DNA topoisomerase II-type [Parasponia andersonii]      224   2e-61
ref|XP_020113224.1| DNA topoisomerase 2-like [Ananas comosus]         211   1e-59
gb|EOY18139.1| Topoisomerase II isoform 3 [Theobroma cacao]           218   2e-59
gb|EOY18138.1| DNA topoisomerase 2 isoform 2 [Theobroma cacao]        218   2e-59
gb|EOY18137.1| DNA topoisomerase 2 isoform 1 [Theobroma cacao]        218   2e-59
gb|ESR52318.1| hypothetical protein CICLE_v10030505mg [Citrus cl...   217   6e-59
dbj|GAY37029.1| hypothetical protein CUMW_026090 [Citrus unshiu]      217   6e-59
ref|XP_006482851.1| PREDICTED: DNA topoisomerase 2 [Citrus sinen...   217   6e-59
ref|XP_006439079.1| DNA topoisomerase 2 isoform X2 [Citrus cleme...   217   6e-59
ref|XP_024041601.1| DNA topoisomerase 2 isoform X1 [Citrus cleme...   217   6e-59
dbj|GAY37030.1| hypothetical protein CUMW_026090 [Citrus unshiu]      217   6e-59
ref|XP_021824766.1| DNA topoisomerase 2 isoform X2 [Prunus avium]     216   1e-58
ref|XP_021824765.1| DNA topoisomerase 2 isoform X1 [Prunus avium]     216   1e-58

>ref|XP_021977342.1| DNA topoisomerase 2-like [Helianthus annuus]
 gb|OTG37224.1| putative topoisomerase II [Helianthus annuus]
          Length = 1499

 Score =  239 bits (609), Expect = 2e-66
 Identities = 159/352 (45%), Positives = 201/352 (57%), Gaps = 42/352 (11%)
 Frame = -3

Query: 1142 NGSEGRGVGCSSFIPNYNPRDIIANLKRLIQGKEVVSTCPWYRGFKGDIQKEKESKGILY 963
            NGSEG G G SSFIPNYNPRDIIANLKRL+ G+++V   PWY+ FKG IQK   SK   Y
Sbjct: 834  NGSEGIGTGWSSFIPNYNPRDIIANLKRLLNGEQMVPMDPWYKWFKGTIQKTT-SKDTGY 892

Query: 962  TTKGIIKQ--ENNVLTINELPVGTWTNNYMEFLKEASQVGKD----IKDYRVRECHIND- 804
            TT G+ ++  +NN L I ELP+  WT  Y EFL+ AS  GKD    I++Y     H +D 
Sbjct: 893  TTVGVFEENEDNNSLNITELPIRRWTQEYKEFLEAASLSGKDKEPFIEEYNA---HNDDT 949

Query: 803  -VDFEVTMTADCAKQEAKQEGVLLEKLNLTTILSTANMHVLNEIGELKKYDTPEQILEDF 627
             V FEV MTA+    +AK+EG LL+K  LTT LST+NMH+ +  G +KKYDTPEQILEDF
Sbjct: 950  TVHFEVVMTAN-QMNKAKEEG-LLKKFKLTTTLSTSNMHLFDANGVIKKYDTPEQILEDF 1007

Query: 626  YRFRLDLYKKRKQALIRELKIASRVLGNKVEFINKVLLSEIALFPLYGKDKRFAELKGKG 447
            +  RLD Y+KRK AL+ EL  AS  L NKV FI +V+   + +      D   AELK KG
Sbjct: 1008 FHLRLDYYEKRKNALLHELGKASLQLENKVRFIREVVEGTLVVSNRKKAD-LCAELKVKG 1066

Query: 446  FQSLP-------SIVHEVDH--HTKETEDNI-------------------------TGYD 369
            +  LP       SI   VDH   ++ETE+                           T YD
Sbjct: 1067 YTPLPKEAVLEASIAGAVDHVEGSEETEEGSEEETAEMAVEEQKPSAGTASKTIPGTEYD 1126

Query: 368  YLLSTPVASFTYXXXXXXXXXXXXXXXXXXKLDFTSPESLWIRDLEALDSQL 213
            YLLS  + + TY                  +L  T  +SLW+RDL++L++QL
Sbjct: 1127 YLLSMAIGTLTYEKMQQLWHERDTKKAEFDELTNTPSKSLWLRDLDSLNNQL 1178


>ref|XP_023759895.1| DNA topoisomerase 2 [Lactuca sativa]
          Length = 1508

 Score =  238 bits (607), Expect = 3e-66
 Identities = 156/344 (45%), Positives = 198/344 (57%), Gaps = 34/344 (9%)
 Frame = -3

Query: 1142 NGSEGRGVGCSSFIPNYNPRDIIANLKRLIQGKEVVSTCPWYRGFKGDIQKEKESKGILY 963
            NGSEG G G S+F+PNYNPRDIIANLKRL+ G+E+V   PWY+ F+G IQK   SK   Y
Sbjct: 835  NGSEGIGTGWSTFVPNYNPRDIIANLKRLLNGEEMVPMDPWYKWFRGTIQKTA-SKDTGY 893

Query: 962  TTKGIIKQEN--NVLTINELPVGTWTNNYMEFLKEASQVGKD----IKDYRVRECHIND- 804
            TT GI+ ++   N L I ELPV  WT  Y EFL+ AS  GKD    I++Y     H +D 
Sbjct: 894  TTTGIVDEDEDENTLRITELPVRRWTQEYKEFLEVASTAGKDKEPFIEEYNA---HNDDT 950

Query: 803  -VDFEVTMTADCAKQEAKQEGVLLEKLNLTTILSTANMHVLNEIGELKKYDTPEQILEDF 627
             V+F++ MTAD    +A+QEG LL+K  LTT LST+NMH+ +  G +KKYDTPEQILEDF
Sbjct: 951  TVNFQIIMTAD-QMNKARQEG-LLKKFKLTTTLSTSNMHLFDANGVIKKYDTPEQILEDF 1008

Query: 626  YRFRLDLYKKRKQALIRELKIASRVLGNKVEFINKVLLSEIALFPLYGKDKRFAELKGKG 447
            +  RLD Y++RK AL+REL   S  L NKV FI +V+   + +      D  +AEL  K 
Sbjct: 1009 FPLRLDYYERRKTALLRELGKISLTLENKVRFIKEVVEGTLVVSNRKKAD-LYAELAKKK 1067

Query: 446  FQSLP-------SIVHEVDH--HTKETEDNI-----------------TGYDYLLSTPVA 345
            +  LP       SI   VDH   ++ETE+                   T YDYLLS  +A
Sbjct: 1068 YTPLPKEAVIEASIAGAVDHVEGSEETEEEEASDVPIDVEAAAAXIPGTEYDYLLSMAIA 1127

Query: 344  SFTYXXXXXXXXXXXXXXXXXXKLDFTSPESLWIRDLEALDSQL 213
            S TY                  +L  T   SLW++DL+ LD QL
Sbjct: 1128 SLTYEKMKQLWKERDEKKAEFDELTNTPSRSLWLKDLDDLDKQL 1171


>ref|XP_022005320.1| DNA topoisomerase 2-like [Helianthus annuus]
 gb|OTF98638.1| putative DNA topoisomerase 2 [Helianthus annuus]
          Length = 1488

 Score =  236 bits (603), Expect = 1e-65
 Identities = 161/354 (45%), Positives = 196/354 (55%), Gaps = 44/354 (12%)
 Frame = -3

Query: 1142 NGSEGRGVGCSSFIPNYNPRDIIANLKRLIQGKEVVSTCPWYRGFKGDIQKEKESKGILY 963
            NGSEG G G SSF+PNYNPRDIIANLKRL+ G+ +V   PWY+ FKG IQK   SK   Y
Sbjct: 821  NGSEGIGTGWSSFVPNYNPRDIIANLKRLLNGEPMVPMDPWYKWFKGTIQKTT-SKDTGY 879

Query: 962  TTKGII--KQENNVLTINELPVGTWTNNYMEFLKEASQVGKD----IKDYRVRECHIND- 804
            TT G +  K++ N L+I ELP+  WT  Y EFL+ AS  GKD    I++Y     H +D 
Sbjct: 880  TTIGNVEEKEDENALSITELPIRRWTQEYKEFLEAASLSGKDKEPFIEEYNA---HNDDT 936

Query: 803  -VDFEVTMTADCAKQEAKQEGVLLEKLNLTTILSTANMHVLNEIGELKKYDTPEQILEDF 627
             V FEV MTA     +AK+EG LL+K  LTT LST+NMH+ +  G +KKYDTPEQILEDF
Sbjct: 937  TVHFEVIMTAS-QMNKAKEEG-LLKKFKLTTTLSTSNMHLFDANGVIKKYDTPEQILEDF 994

Query: 626  YRFRLDLYKKRKQALIRELKIASRVLGNKVEFINKVLLSEIALFPLYGKDKRFAELKGKG 447
            +  RLD Y+KRK AL+ EL  AS +L NKV FI +V+   I +      D   AELK KG
Sbjct: 995  FHLRLDFYEKRKVALLHELGKASLILENKVRFIREVVEGTIVVSNRKKAD-LCAELKVKG 1053

Query: 446  FQSLP-------SIVHEVDH--HTKETEDNI---------------------------TG 375
            F  LP       SI   VDH   + ETE+                             T 
Sbjct: 1054 FTPLPKEAVLEASIAGAVDHVEGSDETEEEEGSGSPADVAAVEEEKSHVGTASKTIPGTE 1113

Query: 374  YDYLLSTPVASFTYXXXXXXXXXXXXXXXXXXKLDFTSPESLWIRDLEALDSQL 213
            YDYLLS  + + TY                  +L  T  +SLW+RDL AL  QL
Sbjct: 1114 YDYLLSMAIGTLTYEKMKQLWHERDTKKAEFDELTNTPSKSLWLRDLNALSDQL 1167


>gb|PLY88472.1| hypothetical protein LSAT_1X105720 [Lactuca sativa]
          Length = 1508

 Score =  236 bits (603), Expect = 1e-65
 Identities = 155/344 (45%), Positives = 197/344 (57%), Gaps = 34/344 (9%)
 Frame = -3

Query: 1142 NGSEGRGVGCSSFIPNYNPRDIIANLKRLIQGKEVVSTCPWYRGFKGDIQKEKESKGILY 963
            NGSEG G G S+F+PNYNPRDIIANLKRL+ G+E+V   PWY+ F+G IQK   SK   Y
Sbjct: 835  NGSEGIGTGWSTFVPNYNPRDIIANLKRLLNGEEMVPMDPWYKWFRGTIQKTA-SKDTGY 893

Query: 962  TTKGIIKQEN--NVLTINELPVGTWTNNYMEFLKEASQVGKD----IKDYRVRECHIND- 804
            TT GI+ ++   N L I ELPV  WT  Y EFL+ AS  GKD    I++Y     H +D 
Sbjct: 894  TTTGIVDEDEDENTLRITELPVRRWTQEYKEFLEVASTAGKDKEPFIEEYNA---HNDDT 950

Query: 803  -VDFEVTMTADCAKQEAKQEGVLLEKLNLTTILSTANMHVLNEIGELKKYDTPEQILEDF 627
             V+F++ MTAD    +A+QEG LL+K  LTT LST+NMH+ +  G +KKYDTPEQILEDF
Sbjct: 951  TVNFQIIMTAD-QMNKARQEG-LLKKFKLTTTLSTSNMHLFDANGVIKKYDTPEQILEDF 1008

Query: 626  YRFRLDLYKKRKQALIRELKIASRVLGNKVEFINKVLLSEIALFPLYGKDKRFAELKGKG 447
            +  RLD Y++RK  L+REL   S  L NKV FI +V+   + +      D  +AEL  K 
Sbjct: 1009 FPLRLDYYERRKATLLRELGKISLTLENKVRFIKEVVEGTLVVSNRKKAD-LYAELAKKK 1067

Query: 446  FQSLP-------SIVHEVDH--HTKETEDNI-----------------TGYDYLLSTPVA 345
            +  LP       SI   VDH   ++ETE+                   T YDYLLS  +A
Sbjct: 1068 YTPLPKEAVIEASIAGAVDHVEGSEETEEEEASDVPIDVEAAAAXIPGTEYDYLLSMAIA 1127

Query: 344  SFTYXXXXXXXXXXXXXXXXXXKLDFTSPESLWIRDLEALDSQL 213
            S TY                  +L  T   SLW++DL+ LD QL
Sbjct: 1128 SLTYEKMKQLWKERDEKKAEFDELTNTPSRSLWLKDLDDLDKQL 1171


>ref|XP_015881654.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Ziziphus jujuba]
          Length = 1486

 Score =  226 bits (576), Expect = 4e-62
 Identities = 140/330 (42%), Positives = 186/330 (56%), Gaps = 20/330 (6%)
 Frame = -3

Query: 1142 NGSEGRGVGCSSFIPNYNPRDIIANLKRLIQGKEVVSTCPWYRGFKGDIQKEKESKGILY 963
            NGSEG G G SS+IPNYNPRDI+AN++RL+ G  +V   PWYRGFKG I+K  +  G+ Y
Sbjct: 843  NGSEGIGTGWSSYIPNYNPRDIVANIRRLLNGHSMVPMDPWYRGFKGTIEKTVKEAGVSY 902

Query: 962  TTKGIIKQEN-NVLTINELPVGTWTNNYMEFLKEASQVGKDIKD-----YRVRECHINDV 801
            T  GI+++ N   + I ELP+  WT +Y EFL+  SQ     KD     +     HI  V
Sbjct: 903  TISGILEEVNETTIRITELPIRKWTQDYKEFLESISQGNDKAKDPFIEGFTQHSDHIT-V 961

Query: 800  DFEVTMTADCAKQEAKQEGVLLEKLNLTTILSTANMHVLNEIGELKKYDTPEQILEDFYR 621
            D  V M  +     AKQEG LL+K  LTT +ST+NMH+ +  G +KKYDTPEQILE+F+ 
Sbjct: 962  DILVHMPEE-NLVAAKQEG-LLKKFKLTTTISTSNMHLFDAKGVIKKYDTPEQILEEFFH 1019

Query: 620  FRLDLYKKRKQALIRELKIASRVLGNKVEFINKVLLSEIALFPLYGKDKRFAELKGKGFQ 441
             RL+ Y+KRKQ L+  L++    L NKV FI  V+  EI +      D  F EL+ KGF 
Sbjct: 1020 LRLEFYEKRKQVLLDNLEMELLKLENKVRFILGVVNEEIIVSNRKRAD-LFLELQQKGFT 1078

Query: 440  SLPSIVHEVD-------HHTKETEDN-------ITGYDYLLSTPVASFTYXXXXXXXXXX 303
              P     V+        +T+ETEDN       I+ Y+YLLS  + + T           
Sbjct: 1079 PFPKKAKSVEPEVAGATDYTEETEDNSNPDGVRISDYEYLLSMAIGTLTLEKVQALCAER 1138

Query: 302  XXXXXXXXKLDFTSPESLWIRDLEALDSQL 213
                     L   +P+SLW +DL+ALD +L
Sbjct: 1139 DKLNGEVDDLRKATPKSLWEKDLDALDKEL 1168


>ref|XP_015881653.1| PREDICTED: DNA topoisomerase 2 isoform X1 [Ziziphus jujuba]
          Length = 1487

 Score =  226 bits (576), Expect = 4e-62
 Identities = 140/330 (42%), Positives = 186/330 (56%), Gaps = 20/330 (6%)
 Frame = -3

Query: 1142 NGSEGRGVGCSSFIPNYNPRDIIANLKRLIQGKEVVSTCPWYRGFKGDIQKEKESKGILY 963
            NGSEG G G SS+IPNYNPRDI+AN++RL+ G  +V   PWYRGFKG I+K  +  G+ Y
Sbjct: 843  NGSEGIGTGWSSYIPNYNPRDIVANIRRLLNGHSMVPMDPWYRGFKGTIEKTVKEAGVSY 902

Query: 962  TTKGIIKQEN-NVLTINELPVGTWTNNYMEFLKEASQVGKDIKD-----YRVRECHINDV 801
            T  GI+++ N   + I ELP+  WT +Y EFL+  SQ     KD     +     HI  V
Sbjct: 903  TISGILEEVNETTIRITELPIRKWTQDYKEFLESISQGNDKAKDPFIEGFTQHSDHIT-V 961

Query: 800  DFEVTMTADCAKQEAKQEGVLLEKLNLTTILSTANMHVLNEIGELKKYDTPEQILEDFYR 621
            D  V M  +     AKQEG LL+K  LTT +ST+NMH+ +  G +KKYDTPEQILE+F+ 
Sbjct: 962  DILVHMPEE-NLVAAKQEG-LLKKFKLTTTISTSNMHLFDAKGVIKKYDTPEQILEEFFH 1019

Query: 620  FRLDLYKKRKQALIRELKIASRVLGNKVEFINKVLLSEIALFPLYGKDKRFAELKGKGFQ 441
             RL+ Y+KRKQ L+  L++    L NKV FI  V+  EI +      D  F EL+ KGF 
Sbjct: 1020 LRLEFYEKRKQVLLDNLEMELLKLENKVRFILGVVNEEIIVSNRKRAD-LFLELQQKGFT 1078

Query: 440  SLPSIVHEVD-------HHTKETEDN-------ITGYDYLLSTPVASFTYXXXXXXXXXX 303
              P     V+        +T+ETEDN       I+ Y+YLLS  + + T           
Sbjct: 1079 PFPKKAKSVEPEVAGATDYTEETEDNSNPDGVRISDYEYLLSMAIGTLTLEKVQALCAER 1138

Query: 302  XXXXXXXXKLDFTSPESLWIRDLEALDSQL 213
                     L   +P+SLW +DL+ALD +L
Sbjct: 1139 DKLNGEVDDLRKATPKSLWEKDLDALDKEL 1168


>gb|PON46642.1| DNA topoisomerase II-type [Trema orientalis]
          Length = 1397

 Score =  225 bits (574), Expect = 7e-62
 Identities = 140/333 (42%), Positives = 189/333 (56%), Gaps = 23/333 (6%)
 Frame = -3

Query: 1142 NGSEGRGVGCSSFIPNYNPRDIIANLKRLIQGKEVVSTCPWYRGFKGDIQKEKESKGILY 963
            NGSEG G G SS+IPNYNPRDI+AN++RL+ G E+V   PWYRGFKG I++  +  G  Y
Sbjct: 805  NGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGDEMVPMDPWYRGFKGTIERSSKEGGASY 864

Query: 962  TTKGIIKQEN-NVLTINELPVGTWTNNYMEFLKEASQVGKDIKDYRV----RECHINDVD 798
               GII++ N   + I ELP+  WT +Y EFL+  SQ  +  KD  +    +    + VD
Sbjct: 865  IVSGIIEEVNETTVRITELPIRRWTQDYKEFLESISQGNEKAKDPFIEGFTQHSDHSTVD 924

Query: 797  FEVTMTADCAKQEAKQEGVLLEKLNLTTILSTANMHVLNEIGELKKYDTPEQILEDFYRF 618
              V +  +     AKQEG LL+KL LTT +ST NMH+ +  G +KKYDTPEQILE+F+  
Sbjct: 925  ILVHLPEE-NLMAAKQEG-LLKKLKLTTSISTTNMHLFDANGVIKKYDTPEQILEEFFHL 982

Query: 617  RLDLYKKRKQALIRELKIASRVLGNKVEFINKVLLSEIALFPLYGKDKRFAELKGKGFQS 438
            RL+ Y+KRK+ L+  L++    L NKV FI  V+  EI +      D  F EL+ KGF  
Sbjct: 983  RLEFYEKRKKVLLDNLELDLLKLENKVRFILGVVKGEIIVNNRKRAD-LFVELQKKGFTP 1041

Query: 437  LP----SIVHEVDHHTKETED--------------NITGYDYLLSTPVASFTYXXXXXXX 312
             P    S+  EV   T+ETED               I+ Y+YLLS  + + T        
Sbjct: 1042 FPKKTKSVEPEVAGATEETEDTEDNSNAEAAATEVRISDYEYLLSMAIGTLTLEKVQALL 1101

Query: 311  XXXXXXXXXXXKLDFTSPESLWIRDLEALDSQL 213
                       +L   +P+SLW+RDL+ALD+QL
Sbjct: 1102 AERDKLNNEVDELRKATPKSLWVRDLDALDTQL 1134


>gb|PON74229.1| DNA topoisomerase II-type [Parasponia andersonii]
          Length = 1397

 Score =  224 bits (570), Expect = 2e-61
 Identities = 139/333 (41%), Positives = 188/333 (56%), Gaps = 23/333 (6%)
 Frame = -3

Query: 1142 NGSEGRGVGCSSFIPNYNPRDIIANLKRLIQGKEVVSTCPWYRGFKGDIQKEKESKGILY 963
            NGSEG G G SS+IPNYNPRDI+AN++RL+ G E+V   PWYRGFKG I++  +  G  Y
Sbjct: 805  NGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGDEMVPMDPWYRGFKGTIERSSKEGGASY 864

Query: 962  TTKGIIKQEN-NVLTINELPVGTWTNNYMEFLKEASQVGKDIKDYRV----RECHINDVD 798
               GII++ N   + I ELP+  WT +Y EFL+  SQ  +  KD  +    +    + VD
Sbjct: 865  IVSGIIEEVNETTVRITELPIRRWTQDYKEFLESISQGNEKAKDPFIEGFTQHSDHSTVD 924

Query: 797  FEVTMTADCAKQEAKQEGVLLEKLNLTTILSTANMHVLNEIGELKKYDTPEQILEDFYRF 618
              V +  +     AKQEG LL+K  LTT +ST NMH+ +  G +KKYDTPEQILE+F+  
Sbjct: 925  ILVHLPEE-NLMAAKQEG-LLKKFKLTTSISTTNMHLFDANGVIKKYDTPEQILEEFFHL 982

Query: 617  RLDLYKKRKQALIRELKIASRVLGNKVEFINKVLLSEIALFPLYGKDKRFAELKGKGFQS 438
            RL+ Y+KRK+ L+  L++    L NKV FI  V+  EI +      D  F EL+ KGF  
Sbjct: 983  RLEFYEKRKKVLLDNLELDLLKLENKVRFILGVVKGEIIVNNRKRAD-LFVELQKKGFTP 1041

Query: 437  LP----SIVHEVDHHTKETED--------------NITGYDYLLSTPVASFTYXXXXXXX 312
             P    S+  EV   T+ETED               I+ Y+YLLS  + + T        
Sbjct: 1042 FPKKTKSVEPEVAGATEETEDTEDNSNAEAAATEVRISDYEYLLSMAIGTLTLEKVQALL 1101

Query: 311  XXXXXXXXXXXKLDFTSPESLWIRDLEALDSQL 213
                       +L   +P+SLW+RDL+ALD+QL
Sbjct: 1102 AERDKLNNEVDELRKATPKSLWVRDLDALDTQL 1134


>ref|XP_020113224.1| DNA topoisomerase 2-like [Ananas comosus]
          Length = 536

 Score =  211 bits (536), Expect = 1e-59
 Identities = 143/339 (42%), Positives = 186/339 (54%), Gaps = 29/339 (8%)
 Frame = -3

Query: 1142 NGSEGRGVGCSSFIPNYNPRDIIANLKRLIQGKEVVSTCPWYRGFKGDIQKEKESK-GIL 966
            NGSEG G G SSF+PNYNPRDIIAN++RL+  + +    PWYRGFKG I+K    + G+ 
Sbjct: 134  NGSEGIGTGWSSFVPNYNPRDIIANVRRLLNDEPMQPMDPWYRGFKGLIEKSATKEAGVT 193

Query: 965  YTTKGIIKQ-ENNVLTINELPVGTWTNNYMEFLKEASQVGKD------IKDYRVRECHIN 807
            YT  GII++ +N  L I ELPV  WT +Y EFL EA   G D      IKDYR    H +
Sbjct: 194  YTITGIIEEVDNTTLRIMELPVRRWTQDYKEFL-EALMTGNDKVKEPFIKDYRE---HND 249

Query: 806  D--VDFEVTMTADCAKQEAKQEGVLLEKLNLTTILSTANMHVLNEIGELKKYDTPEQILE 633
            D  V FEVT+T +     A QEG L +K  LTT + T NMH+ +  G +KKYDTPEQILE
Sbjct: 250  DTTVHFEVTLTEENLNI-ALQEG-LEKKFKLTTTIGTTNMHLFDSNGVIKKYDTPEQILE 307

Query: 632  DFYRFRLDLYKKRKQALIRELKIASRVLGNKVEFINKVLLSEIALFPLYGKDKR---FAE 462
            DF+  RL+ Y+KRK+ L+  L++    L NKV FI  V+  EI    +    KR   F E
Sbjct: 308  DFFHLRLEFYEKRKKVLLDNLEMDLLKLDNKVRFILGVVRGEI----IVNNRKRAELFIE 363

Query: 461  LKGKGFQSLPSIVHEVD----HHTKETEDN------------ITGYDYLLSTPVASFTYX 330
            L  KGF   P     +D      T E E+N             + Y+YLLS  + + T  
Sbjct: 364  LHQKGFTPFPKKSKGIDVAIVGATTEEEENEESPEMGKGGVRASDYEYLLSMAIGTLTLE 423

Query: 329  XXXXXXXXXXXXXXXXXKLDFTSPESLWIRDLEALDSQL 213
                             +L   +P SLW++DL+AL+ +L
Sbjct: 424  KVQELCGERDKLESEVEELRKATPRSLWLKDLDALEREL 462


>gb|EOY18139.1| Topoisomerase II isoform 3 [Theobroma cacao]
          Length = 1244

 Score =  218 bits (555), Expect = 2e-59
 Identities = 138/330 (41%), Positives = 190/330 (57%), Gaps = 20/330 (6%)
 Frame = -3

Query: 1142 NGSEGRGVGCSSFIPNYNPRDIIANLKRLIQGKEVVSTCPWYRGFKGDIQKEKESK-GIL 966
            NGSEG G G SS+IPNYNPRDI+AN++RL+ G+++    PWYRGFKG+I+K    + G+ 
Sbjct: 831  NGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMHPWYRGFKGNIEKTASKEAGVT 890

Query: 965  YTTKGIIKQ-ENNVLTINELPVGTWTNNYMEFLKEASQVGKD--IKDYRVRECHINDVDF 795
            YT  GII++ +   L I ELPV  WT +Y EFL E+   G D  IK++R +      V+F
Sbjct: 891  YTITGIIEEVDETTLRITELPVRRWTQDYREFL-ESIITGNDPFIKEFR-QYSDDTTVEF 948

Query: 794  EVTMTADCAKQEAKQEGVLLEKLNLTTILSTANMHVLNEIGELKKYDTPEQILEDFYRFR 615
            EV +T +     AKQEG LL+K  LTT +ST+NMH+ +  G +KKYDTPEQILE+F+  R
Sbjct: 949  EVILTEE-NMMVAKQEG-LLKKFKLTTTISTSNMHLFDSKGMIKKYDTPEQILEEFFHLR 1006

Query: 614  LDLYKKRKQALIRELKIASRVLGNKVEFINKVLLSEIALFPLYGKDKRFAELKGKGFQSL 435
             + Y+KRK+ L+  L++    + NKV FI  V+  EI +      D  F EL+ KGF   
Sbjct: 1007 FEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRAD-LFLELQTKGFTPF 1065

Query: 434  PSIVHEVD-------HHTKETEDN---------ITGYDYLLSTPVASFTYXXXXXXXXXX 303
            P     V+         T+ETE+N          + YDYLLS  + S T           
Sbjct: 1066 PKKAKTVEVAVAGATDDTEETEENSEVSAKGLQASDYDYLLSMAIGSLTLEKVQELCADR 1125

Query: 302  XXXXXXXXKLDFTSPESLWIRDLEALDSQL 213
                     L   +P+SLW++DL+ L+ QL
Sbjct: 1126 DKLQQEVEDLRKATPKSLWLKDLDNLEIQL 1155


>gb|EOY18138.1| DNA topoisomerase 2 isoform 2 [Theobroma cacao]
          Length = 1285

 Score =  218 bits (555), Expect = 2e-59
 Identities = 138/330 (41%), Positives = 190/330 (57%), Gaps = 20/330 (6%)
 Frame = -3

Query: 1142 NGSEGRGVGCSSFIPNYNPRDIIANLKRLIQGKEVVSTCPWYRGFKGDIQKEKESK-GIL 966
            NGSEG G G SS+IPNYNPRDI+AN++RL+ G+++    PWYRGFKG+I+K    + G+ 
Sbjct: 642  NGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMHPWYRGFKGNIEKTASKEAGVT 701

Query: 965  YTTKGIIKQ-ENNVLTINELPVGTWTNNYMEFLKEASQVGKD--IKDYRVRECHINDVDF 795
            YT  GII++ +   L I ELPV  WT +Y EFL E+   G D  IK++R +      V+F
Sbjct: 702  YTITGIIEEVDETTLRITELPVRRWTQDYREFL-ESIITGNDPFIKEFR-QYSDDTTVEF 759

Query: 794  EVTMTADCAKQEAKQEGVLLEKLNLTTILSTANMHVLNEIGELKKYDTPEQILEDFYRFR 615
            EV +T +     AKQEG LL+K  LTT +ST+NMH+ +  G +KKYDTPEQILE+F+  R
Sbjct: 760  EVILTEE-NMMVAKQEG-LLKKFKLTTTISTSNMHLFDSKGMIKKYDTPEQILEEFFHLR 817

Query: 614  LDLYKKRKQALIRELKIASRVLGNKVEFINKVLLSEIALFPLYGKDKRFAELKGKGFQSL 435
             + Y+KRK+ L+  L++    + NKV FI  V+  EI +      D  F EL+ KGF   
Sbjct: 818  FEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRAD-LFLELQTKGFTPF 876

Query: 434  PSIVHEVD-------HHTKETEDN---------ITGYDYLLSTPVASFTYXXXXXXXXXX 303
            P     V+         T+ETE+N          + YDYLLS  + S T           
Sbjct: 877  PKKAKTVEVAVAGATDDTEETEENSEVSAKGLQASDYDYLLSMAIGSLTLEKVQELCADR 936

Query: 302  XXXXXXXXKLDFTSPESLWIRDLEALDSQL 213
                     L   +P+SLW++DL+ L+ QL
Sbjct: 937  DKLQQEVEDLRKATPKSLWLKDLDNLEIQL 966


>gb|EOY18137.1| DNA topoisomerase 2 isoform 1 [Theobroma cacao]
          Length = 1473

 Score =  218 bits (555), Expect = 2e-59
 Identities = 138/330 (41%), Positives = 190/330 (57%), Gaps = 20/330 (6%)
 Frame = -3

Query: 1142 NGSEGRGVGCSSFIPNYNPRDIIANLKRLIQGKEVVSTCPWYRGFKGDIQKEKESK-GIL 966
            NGSEG G G SS+IPNYNPRDI+AN++RL+ G+++    PWYRGFKG+I+K    + G+ 
Sbjct: 831  NGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMHPWYRGFKGNIEKTASKEAGVT 890

Query: 965  YTTKGIIKQ-ENNVLTINELPVGTWTNNYMEFLKEASQVGKD--IKDYRVRECHINDVDF 795
            YT  GII++ +   L I ELPV  WT +Y EFL E+   G D  IK++R +      V+F
Sbjct: 891  YTITGIIEEVDETTLRITELPVRRWTQDYREFL-ESIITGNDPFIKEFR-QYSDDTTVEF 948

Query: 794  EVTMTADCAKQEAKQEGVLLEKLNLTTILSTANMHVLNEIGELKKYDTPEQILEDFYRFR 615
            EV +T +     AKQEG LL+K  LTT +ST+NMH+ +  G +KKYDTPEQILE+F+  R
Sbjct: 949  EVILTEE-NMMVAKQEG-LLKKFKLTTTISTSNMHLFDSKGMIKKYDTPEQILEEFFHLR 1006

Query: 614  LDLYKKRKQALIRELKIASRVLGNKVEFINKVLLSEIALFPLYGKDKRFAELKGKGFQSL 435
             + Y+KRK+ L+  L++    + NKV FI  V+  EI +      D  F EL+ KGF   
Sbjct: 1007 FEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRAD-LFLELQTKGFTPF 1065

Query: 434  PSIVHEVD-------HHTKETEDN---------ITGYDYLLSTPVASFTYXXXXXXXXXX 303
            P     V+         T+ETE+N          + YDYLLS  + S T           
Sbjct: 1066 PKKAKTVEVAVAGATDDTEETEENSEVSAKGLQASDYDYLLSMAIGSLTLEKVQELCADR 1125

Query: 302  XXXXXXXXKLDFTSPESLWIRDLEALDSQL 213
                     L   +P+SLW++DL+ L+ QL
Sbjct: 1126 DKLQQEVEDLRKATPKSLWLKDLDNLEIQL 1155


>gb|ESR52318.1| hypothetical protein CICLE_v10030505mg [Citrus clementina]
          Length = 1455

 Score =  217 bits (552), Expect = 6e-59
 Identities = 135/328 (41%), Positives = 189/328 (57%), Gaps = 18/328 (5%)
 Frame = -3

Query: 1142 NGSEGRGVGCSSFIPNYNPRDIIANLKRLIQGKEVVSTCPWYRGFKGDIQKEKESK-GIL 966
            NGSEG G G SS+IPNYNPRDI+AN++RL+ G+ +    PWYRGF+G I+K    + G+ 
Sbjct: 830  NGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEMMEPMHPWYRGFRGTIEKTASKEAGVT 889

Query: 965  YTTKGIIKQENNV-LTINELPVGTWTNNYMEFLKEA-SQVGKDIKDYRVRECHINDVDFE 792
            YT  GII++ N   L I ELP+  WT +Y EFL+    Q    I+ +R +      VDFE
Sbjct: 890  YTVTGIIEEVNETTLRIKELPIRRWTQDYREFLESIIDQNDSFIRGFR-QYSDDTTVDFE 948

Query: 791  VTMTADCAKQEAKQEGVLLEKLNLTTILSTANMHVLNEIGELKKYDTPEQILEDFYRFRL 612
            V ++ + +    KQEG LL+K  LTT +ST+NMH+ +  G +KKYDTPEQILE+F+  RL
Sbjct: 949  VFLSEE-SMMRTKQEG-LLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEQILEEFFHIRL 1006

Query: 611  DLYKKRKQALIRELKIASRVLGNKVEFINKVLLSEIALFPLYGKDKRFAELKGKGF---- 444
            + Y+KRK+  +  L++    L NKV FI  V+  EI +      D    EL+ KGF    
Sbjct: 1007 EFYEKRKKVQLENLELELLKLENKVRFILGVVNGEIVVNNRKRTD-LLLELRQKGFTPFP 1065

Query: 443  ---QSLPSIVHEVDHHTKETEDN---ITG-----YDYLLSTPVASFTYXXXXXXXXXXXX 297
               +S+ ++V      T+E+E+N   + G     YDYLLS  + + T             
Sbjct: 1066 KNSKSIEAVVAGATDETEESEENPEVVNGVQSIDYDYLLSMAIGTLTLEKVQGLLADRDK 1125

Query: 296  XXXXXXKLDFTSPESLWIRDLEALDSQL 213
                   L   +PESLW++DL+ALD QL
Sbjct: 1126 LNEEVDDLRKATPESLWVKDLDALDMQL 1153


>dbj|GAY37029.1| hypothetical protein CUMW_026090 [Citrus unshiu]
          Length = 1456

 Score =  217 bits (552), Expect = 6e-59
 Identities = 135/328 (41%), Positives = 189/328 (57%), Gaps = 18/328 (5%)
 Frame = -3

Query: 1142 NGSEGRGVGCSSFIPNYNPRDIIANLKRLIQGKEVVSTCPWYRGFKGDIQKEKESK-GIL 966
            NGSEG G G SS+IPNYNPRDI+AN++RL+ G+ +    PWYRGF+G I+K    + G+ 
Sbjct: 830  NGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEMMEPMHPWYRGFRGTIEKTASKEAGVT 889

Query: 965  YTTKGIIKQENNV-LTINELPVGTWTNNYMEFLKEA-SQVGKDIKDYRVRECHINDVDFE 792
            YT  GII++ N   L I ELP+  WT +Y EFL+    Q    I+ +R +      VDFE
Sbjct: 890  YTVTGIIEEVNETTLRIKELPIRRWTQDYREFLESIIDQNDSFIRGFR-QYSDDTTVDFE 948

Query: 791  VTMTADCAKQEAKQEGVLLEKLNLTTILSTANMHVLNEIGELKKYDTPEQILEDFYRFRL 612
            V ++ + +    KQEG LL+K  LTT +ST+NMH+ +  G +KKYDTPEQILE+F+  RL
Sbjct: 949  VFLSEE-SMMRTKQEG-LLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEQILEEFFHIRL 1006

Query: 611  DLYKKRKQALIRELKIASRVLGNKVEFINKVLLSEIALFPLYGKDKRFAELKGKGF---- 444
            + Y+KRK+  +  L++    L NKV FI  V+  EI +      D    EL+ KGF    
Sbjct: 1007 EFYEKRKKVQLENLELELLKLENKVRFILGVVNGEIVVNNRKRTD-LLLELRQKGFTPFP 1065

Query: 443  ---QSLPSIVHEVDHHTKETEDN---ITG-----YDYLLSTPVASFTYXXXXXXXXXXXX 297
               +S+ ++V      T+E+E+N   + G     YDYLLS  + + T             
Sbjct: 1066 KNSKSIEAVVAGATDETEESEENPEVVNGVQSIDYDYLLSMAIGTLTLEKVQGLLADRDK 1125

Query: 296  XXXXXXKLDFTSPESLWIRDLEALDSQL 213
                   L   +PESLW++DL+ALD QL
Sbjct: 1126 LNEEVDDLRKATPESLWVKDLDALDMQL 1153


>ref|XP_006482851.1| PREDICTED: DNA topoisomerase 2 [Citrus sinensis]
          Length = 1456

 Score =  217 bits (552), Expect = 6e-59
 Identities = 135/328 (41%), Positives = 189/328 (57%), Gaps = 18/328 (5%)
 Frame = -3

Query: 1142 NGSEGRGVGCSSFIPNYNPRDIIANLKRLIQGKEVVSTCPWYRGFKGDIQKEKESK-GIL 966
            NGSEG G G SS+IPNYNPRDI+AN++RL+ G+ +    PWYRGF+G I+K    + G+ 
Sbjct: 830  NGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEMMEPMHPWYRGFRGTIEKTASKEAGVT 889

Query: 965  YTTKGIIKQENNV-LTINELPVGTWTNNYMEFLKEA-SQVGKDIKDYRVRECHINDVDFE 792
            YT  GII++ N   L I ELP+  WT +Y EFL+    Q    I+ +R +      VDFE
Sbjct: 890  YTVTGIIEEVNETTLRIKELPIRRWTQDYREFLESIIDQNDSFIRGFR-QYSDDTTVDFE 948

Query: 791  VTMTADCAKQEAKQEGVLLEKLNLTTILSTANMHVLNEIGELKKYDTPEQILEDFYRFRL 612
            V ++ + +    KQEG LL+K  LTT +ST+NMH+ +  G +KKYDTPEQILE+F+  RL
Sbjct: 949  VFLSEE-SMMRTKQEG-LLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEQILEEFFHIRL 1006

Query: 611  DLYKKRKQALIRELKIASRVLGNKVEFINKVLLSEIALFPLYGKDKRFAELKGKGF---- 444
            + Y+KRK+  +  L++    L NKV FI  V+  EI +      D    EL+ KGF    
Sbjct: 1007 EFYEKRKKVQLENLELELLKLENKVRFILGVVNGEIVVNNRKRTD-LLLELRQKGFTPFP 1065

Query: 443  ---QSLPSIVHEVDHHTKETEDN---ITG-----YDYLLSTPVASFTYXXXXXXXXXXXX 297
               +S+ ++V      T+E+E+N   + G     YDYLLS  + + T             
Sbjct: 1066 KNSKSIEAVVAGATDETEESEENPEVVNGVQSIDYDYLLSMAIGTLTLEKVQGLLADRDK 1125

Query: 296  XXXXXXKLDFTSPESLWIRDLEALDSQL 213
                   L   +PESLW++DL+ALD QL
Sbjct: 1126 LNEEVDDLRKATPESLWVKDLDALDMQL 1153


>ref|XP_006439079.1| DNA topoisomerase 2 isoform X2 [Citrus clementina]
 gb|ESR52319.1| hypothetical protein CICLE_v10030505mg [Citrus clementina]
          Length = 1456

 Score =  217 bits (552), Expect = 6e-59
 Identities = 135/328 (41%), Positives = 189/328 (57%), Gaps = 18/328 (5%)
 Frame = -3

Query: 1142 NGSEGRGVGCSSFIPNYNPRDIIANLKRLIQGKEVVSTCPWYRGFKGDIQKEKESK-GIL 966
            NGSEG G G SS+IPNYNPRDI+AN++RL+ G+ +    PWYRGF+G I+K    + G+ 
Sbjct: 830  NGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEMMEPMHPWYRGFRGTIEKTASKEAGVT 889

Query: 965  YTTKGIIKQENNV-LTINELPVGTWTNNYMEFLKEA-SQVGKDIKDYRVRECHINDVDFE 792
            YT  GII++ N   L I ELP+  WT +Y EFL+    Q    I+ +R +      VDFE
Sbjct: 890  YTVTGIIEEVNETTLRIKELPIRRWTQDYREFLESIIDQNDSFIRGFR-QYSDDTTVDFE 948

Query: 791  VTMTADCAKQEAKQEGVLLEKLNLTTILSTANMHVLNEIGELKKYDTPEQILEDFYRFRL 612
            V ++ + +    KQEG LL+K  LTT +ST+NMH+ +  G +KKYDTPEQILE+F+  RL
Sbjct: 949  VFLSEE-SMMRTKQEG-LLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEQILEEFFHIRL 1006

Query: 611  DLYKKRKQALIRELKIASRVLGNKVEFINKVLLSEIALFPLYGKDKRFAELKGKGF---- 444
            + Y+KRK+  +  L++    L NKV FI  V+  EI +      D    EL+ KGF    
Sbjct: 1007 EFYEKRKKVQLENLELELLKLENKVRFILGVVNGEIVVNNRKRTD-LLLELRQKGFTPFP 1065

Query: 443  ---QSLPSIVHEVDHHTKETEDN---ITG-----YDYLLSTPVASFTYXXXXXXXXXXXX 297
               +S+ ++V      T+E+E+N   + G     YDYLLS  + + T             
Sbjct: 1066 KNSKSIEAVVAGATDETEESEENPEVVNGVQSIDYDYLLSMAIGTLTLEKVQGLLADRDK 1125

Query: 296  XXXXXXKLDFTSPESLWIRDLEALDSQL 213
                   L   +PESLW++DL+ALD QL
Sbjct: 1126 LNEEVDDLRKATPESLWVKDLDALDMQL 1153


>ref|XP_024041601.1| DNA topoisomerase 2 isoform X1 [Citrus clementina]
          Length = 1484

 Score =  217 bits (552), Expect = 6e-59
 Identities = 135/328 (41%), Positives = 189/328 (57%), Gaps = 18/328 (5%)
 Frame = -3

Query: 1142 NGSEGRGVGCSSFIPNYNPRDIIANLKRLIQGKEVVSTCPWYRGFKGDIQKEKESK-GIL 966
            NGSEG G G SS+IPNYNPRDI+AN++RL+ G+ +    PWYRGF+G I+K    + G+ 
Sbjct: 858  NGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEMMEPMHPWYRGFRGTIEKTASKEAGVT 917

Query: 965  YTTKGIIKQENNV-LTINELPVGTWTNNYMEFLKEA-SQVGKDIKDYRVRECHINDVDFE 792
            YT  GII++ N   L I ELP+  WT +Y EFL+    Q    I+ +R +      VDFE
Sbjct: 918  YTVTGIIEEVNETTLRIKELPIRRWTQDYREFLESIIDQNDSFIRGFR-QYSDDTTVDFE 976

Query: 791  VTMTADCAKQEAKQEGVLLEKLNLTTILSTANMHVLNEIGELKKYDTPEQILEDFYRFRL 612
            V ++ + +    KQEG LL+K  LTT +ST+NMH+ +  G +KKYDTPEQILE+F+  RL
Sbjct: 977  VFLSEE-SMMRTKQEG-LLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEQILEEFFHIRL 1034

Query: 611  DLYKKRKQALIRELKIASRVLGNKVEFINKVLLSEIALFPLYGKDKRFAELKGKGF---- 444
            + Y+KRK+  +  L++    L NKV FI  V+  EI +      D    EL+ KGF    
Sbjct: 1035 EFYEKRKKVQLENLELELLKLENKVRFILGVVNGEIVVNNRKRTD-LLLELRQKGFTPFP 1093

Query: 443  ---QSLPSIVHEVDHHTKETEDN---ITG-----YDYLLSTPVASFTYXXXXXXXXXXXX 297
               +S+ ++V      T+E+E+N   + G     YDYLLS  + + T             
Sbjct: 1094 KNSKSIEAVVAGATDETEESEENPEVVNGVQSIDYDYLLSMAIGTLTLEKVQGLLADRDK 1153

Query: 296  XXXXXXKLDFTSPESLWIRDLEALDSQL 213
                   L   +PESLW++DL+ALD QL
Sbjct: 1154 LNEEVDDLRKATPESLWVKDLDALDMQL 1181


>dbj|GAY37030.1| hypothetical protein CUMW_026090 [Citrus unshiu]
          Length = 1484

 Score =  217 bits (552), Expect = 6e-59
 Identities = 135/328 (41%), Positives = 189/328 (57%), Gaps = 18/328 (5%)
 Frame = -3

Query: 1142 NGSEGRGVGCSSFIPNYNPRDIIANLKRLIQGKEVVSTCPWYRGFKGDIQKEKESK-GIL 966
            NGSEG G G SS+IPNYNPRDI+AN++RL+ G+ +    PWYRGF+G I+K    + G+ 
Sbjct: 858  NGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEMMEPMHPWYRGFRGTIEKTASKEAGVT 917

Query: 965  YTTKGIIKQENNV-LTINELPVGTWTNNYMEFLKEA-SQVGKDIKDYRVRECHINDVDFE 792
            YT  GII++ N   L I ELP+  WT +Y EFL+    Q    I+ +R +      VDFE
Sbjct: 918  YTVTGIIEEVNETTLRIKELPIRRWTQDYREFLESIIDQNDSFIRGFR-QYSDDTTVDFE 976

Query: 791  VTMTADCAKQEAKQEGVLLEKLNLTTILSTANMHVLNEIGELKKYDTPEQILEDFYRFRL 612
            V ++ + +    KQEG LL+K  LTT +ST+NMH+ +  G +KKYDTPEQILE+F+  RL
Sbjct: 977  VFLSEE-SMMRTKQEG-LLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEQILEEFFHIRL 1034

Query: 611  DLYKKRKQALIRELKIASRVLGNKVEFINKVLLSEIALFPLYGKDKRFAELKGKGF---- 444
            + Y+KRK+  +  L++    L NKV FI  V+  EI +      D    EL+ KGF    
Sbjct: 1035 EFYEKRKKVQLENLELELLKLENKVRFILGVVNGEIVVNNRKRTD-LLLELRQKGFTPFP 1093

Query: 443  ---QSLPSIVHEVDHHTKETEDN---ITG-----YDYLLSTPVASFTYXXXXXXXXXXXX 297
               +S+ ++V      T+E+E+N   + G     YDYLLS  + + T             
Sbjct: 1094 KNSKSIEAVVAGATDETEESEENPEVVNGVQSIDYDYLLSMAIGTLTLEKVQGLLADRDK 1153

Query: 296  XXXXXXKLDFTSPESLWIRDLEALDSQL 213
                   L   +PESLW++DL+ALD QL
Sbjct: 1154 LNEEVDDLRKATPESLWVKDLDALDMQL 1181


>ref|XP_021824766.1| DNA topoisomerase 2 isoform X2 [Prunus avium]
          Length = 1469

 Score =  216 bits (550), Expect = 1e-58
 Identities = 133/332 (40%), Positives = 187/332 (56%), Gaps = 22/332 (6%)
 Frame = -3

Query: 1142 NGSEGRGVGCSSFIPNYNPRDIIANLKRLIQGKEVVSTCPWYRGFKGDIQKEKESKGILY 963
            NGSEG G G SS+IPNYNPRDI+AN++RL+ G+ +V   PWYRGF G I+K  +  G+ Y
Sbjct: 837  NGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEAMVPMDPWYRGFSGTIEKTVKESGVSY 896

Query: 962  TTKGIIKQEN-NVLTINELPVGTWTNNYMEFLKEASQVGKDIKDYRV----RECHINDVD 798
            T  GII++ N   + I+ELP+  WT +Y EFL+  SQ     KD  +    +    + VD
Sbjct: 897  TVCGIIEEGNETTVRISELPIRRWTQDYKEFLESISQGNDKAKDPFIEGFTQHSDHSTVD 956

Query: 797  FEVTMTADCAKQEAKQEGVLLEKLNLTTILSTANMHVLNEIGELKKYDTPEQILEDFYRF 618
              V +  +     A+QEG LL+K  LTT +ST+NMH+ +  G +KKYDTPEQILEDF+  
Sbjct: 957  IIVHLPEE-NLMAARQEG-LLKKFKLTTSISTSNMHLFDPKGVIKKYDTPEQILEDFFHL 1014

Query: 617  RLDLYKKRKQALIRELKIASRVLGNKVEFINKVLLSEIALFPLYGKDKRFAELKGKGFQS 438
            RL+ Y+KRK+ L+  L++    L NKV FI  V+  EI +      D  F EL+ KGF  
Sbjct: 1015 RLEFYEKRKKVLLDNLEMELLKLENKVRFILAVVNGEIIVSNRRRAD-LFLELQQKGFTP 1073

Query: 437  LPSIVHEVD-------HHTKETEDN----------ITGYDYLLSTPVASFTYXXXXXXXX 309
             P      +         T+ETE+N          I+ Y+YL+S  + S T         
Sbjct: 1074 FPKKTKAQEPEVAGAIEDTEETEENSESASGNGARISDYEYLISMAIGSLTIERVQALCA 1133

Query: 308  XXXXXXXXXXKLDFTSPESLWIRDLEALDSQL 213
                      +L  ++P SLW++DL+AL+ +L
Sbjct: 1134 DRDKVNNEVAELRNSTPRSLWLKDLDALEMEL 1165


>ref|XP_021824765.1| DNA topoisomerase 2 isoform X1 [Prunus avium]
          Length = 1470

 Score =  216 bits (550), Expect = 1e-58
 Identities = 133/332 (40%), Positives = 187/332 (56%), Gaps = 22/332 (6%)
 Frame = -3

Query: 1142 NGSEGRGVGCSSFIPNYNPRDIIANLKRLIQGKEVVSTCPWYRGFKGDIQKEKESKGILY 963
            NGSEG G G SS+IPNYNPRDI+AN++RL+ G+ +V   PWYRGF G I+K  +  G+ Y
Sbjct: 837  NGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEAMVPMDPWYRGFSGTIEKTVKESGVSY 896

Query: 962  TTKGIIKQEN-NVLTINELPVGTWTNNYMEFLKEASQVGKDIKDYRV----RECHINDVD 798
            T  GII++ N   + I+ELP+  WT +Y EFL+  SQ     KD  +    +    + VD
Sbjct: 897  TVCGIIEEGNETTVRISELPIRRWTQDYKEFLESISQGNDKAKDPFIEGFTQHSDHSTVD 956

Query: 797  FEVTMTADCAKQEAKQEGVLLEKLNLTTILSTANMHVLNEIGELKKYDTPEQILEDFYRF 618
              V +  +     A+QEG LL+K  LTT +ST+NMH+ +  G +KKYDTPEQILEDF+  
Sbjct: 957  IIVHLPEE-NLMAARQEG-LLKKFKLTTSISTSNMHLFDPKGVIKKYDTPEQILEDFFHL 1014

Query: 617  RLDLYKKRKQALIRELKIASRVLGNKVEFINKVLLSEIALFPLYGKDKRFAELKGKGFQS 438
            RL+ Y+KRK+ L+  L++    L NKV FI  V+  EI +      D  F EL+ KGF  
Sbjct: 1015 RLEFYEKRKKVLLDNLEMELLKLENKVRFILAVVNGEIIVSNRRRAD-LFLELQQKGFTP 1073

Query: 437  LPSIVHEVD-------HHTKETEDN----------ITGYDYLLSTPVASFTYXXXXXXXX 309
             P      +         T+ETE+N          I+ Y+YL+S  + S T         
Sbjct: 1074 FPKKTKAQEPEVAGAIEDTEETEENSESASGNGARISDYEYLISMAIGSLTIERVQALCA 1133

Query: 308  XXXXXXXXXXKLDFTSPESLWIRDLEALDSQL 213
                      +L  ++P SLW++DL+AL+ +L
Sbjct: 1134 DRDKVNNEVAELRNSTPRSLWLKDLDALEMEL 1165