BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Chrysanthemum21_contig00033234
         (359 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gb|PLY80976.1| hypothetical protein LSAT_9X107560 [Lactuca sativa]     75   4e-13
gb|PLY73028.1| hypothetical protein LSAT_9X35401 [Lactuca sativa]      74   9e-13
ref|XP_023746224.1| F-box protein At5g03100-like [Lactuca sativa...    72   3e-12
ref|XP_023761558.1| putative F-box/FBD/LRR-repeat protein At1g78...    72   4e-12
ref|XP_023732060.1| uncharacterized protein LOC111879855 isoform...    70   2e-11
gb|PLY97294.1| hypothetical protein LSAT_3X106860 [Lactuca sativa]     70   2e-11
ref|XP_023732415.1| putative F-box/LRR-repeat protein At5g02700 ...    69   4e-11
gb|PLY74936.1| hypothetical protein LSAT_9X12941 [Lactuca sativa]      69   4e-11
ref|XP_023763265.1| uncharacterized protein LOC111911752 [Lactuc...    68   7e-11
ref|XP_023768765.1| F-box/LRR-repeat protein At5g02910-like [Lac...    68   1e-10
ref|XP_023730411.1| putative F-box/LRR-repeat protein At3g28410 ...    66   5e-10
ref|XP_023730410.1| putative F-box/LRR-repeat protein At3g28410 ...    66   5e-10
gb|PLY87227.1| hypothetical protein LSAT_4X154940 [Lactuca sativa]     63   3e-09
ref|XP_023740058.1| putative F-box/LRR-repeat protein At5g02700 ...    60   5e-08
gb|PLY68965.1| hypothetical protein LSAT_9X89481 [Lactuca sativa]      60   5e-08
ref|XP_023761562.1| uncharacterized protein LOC111909993 [Lactuc...    60   6e-08
ref|XP_023773266.1| F-box/LRR-repeat protein At5g02910-like [Lac...    59   2e-07
ref|XP_023761561.1| uncharacterized protein LOC111909991 isoform...    56   1e-06
ref|XP_023761560.1| uncharacterized protein LOC111909991 isoform...    56   1e-06
gb|PLY70261.1| hypothetical protein LSAT_4X116140 [Lactuca sativa]     55   3e-06

>gb|PLY80976.1| hypothetical protein LSAT_9X107560 [Lactuca sativa]
          Length = 500

 Score = 74.7 bits (182), Expect = 4e-13
 Identities = 42/108 (38%), Positives = 60/108 (55%), Gaps = 5/108 (4%)
 Frame = +3

Query: 3   RTRVPFP-ATNVETLSFESFSSNGLWDNLLLFDAFFSICQPMYVRAEGQLRLKVATYFLK 179
           RTR+  P ATNV+ L F++     +W+  L FDAFF IC P  V A+  +R K   +F +
Sbjct: 378 RTRLLLPPATNVQELRFQTTEDECMWERSLFFDAFFEICHPKCVYAKPDVRFKHNNHFCR 437

Query: 180 LIKRAVRKSKTGKVS----GQHLKYGEIRNGCYEKWEKLTGASLSMLD 311
           L+ R V + KT  +       +LK+ +IR   ++KWE LT    S LD
Sbjct: 438 LMLREVLEKKTTTIGIVYWPHYLKHVQIRRALHQKWETLTNFHRSFLD 485


>gb|PLY73028.1| hypothetical protein LSAT_9X35401 [Lactuca sativa]
          Length = 513

 Score = 73.6 bits (179), Expect = 9e-13
 Identities = 40/105 (38%), Positives = 55/105 (52%), Gaps = 8/105 (7%)
 Frame = +3

Query: 21  PATNVETLSFESFSSNGLWDNLLLFDAFFSICQPMYVRAEGQLRLKVATYFLKLIKRAVR 200
           PATNV+ L FE+     LW+    FDAFF IC P +V A+    L+   +F +L+ R   
Sbjct: 394 PATNVQKLEFEAIEDECLWERSPFFDAFFEICHPKHVVAKPDACLRQKNHFCRLMLREFL 453

Query: 201 KSKTGKVS--------GQHLKYGEIRNGCYEKWEKLTGASLSMLD 311
           + KT   +          HL++ +IR   YEKWE LT +  S LD
Sbjct: 454 EKKTTTTTTTTTTPYWPHHLQHVQIRRNSYEKWETLTDSHRSFLD 498


>ref|XP_023746224.1| F-box protein At5g03100-like [Lactuca sativa]
 gb|PLY64363.1| hypothetical protein LSAT_4X14860 [Lactuca sativa]
          Length = 537

 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 47/106 (44%), Positives = 62/106 (58%), Gaps = 3/106 (2%)
 Frame = +3

Query: 3   RTRVPFPATNVETLSFESFSSNGLW-DNLLLFDAFFSICQPMYVRAEGQLRLKVATYFLK 179
           R RVPFPA NV+ +S  +FS +GLW D+   FDAFF IC P +V  +    L   ++F K
Sbjct: 418 RRRVPFPAMNVQRVSLRTFSDDGLWRDSSPFFDAFFMICHPKHVEDQS---LNNNSHFCK 474

Query: 180 LIKRAVRKSKTGKVSGQHLKYGEIRNGCY--EKWEKLTGASLSMLD 311
           L+    +K++ G   G +LK  EIR  C   EKWE LT +  S LD
Sbjct: 475 LM-MLEKKTRKG-YWGDYLKDVEIRRQCLGDEKWETLTNSWRSFLD 518


>ref|XP_023761558.1| putative F-box/FBD/LRR-repeat protein At1g78840 [Lactuca sativa]
 gb|PLY87203.1| hypothetical protein LSAT_4X155001 [Lactuca sativa]
          Length = 538

 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 45/120 (37%), Positives = 65/120 (54%), Gaps = 2/120 (1%)
 Frame = +3

Query: 3   RTRVPFP-ATNVETLSFESFSSNGLWDNLLLFDAFFSICQPMYVRAEGQLRLKVATYFLK 179
           R R+ FP ATNV+ L FE+     +W+    FDAFF IC P  V A+  +  +   +F +
Sbjct: 415 RRRLLFPPATNVKELEFETDEDECMWERSTFFDAFFEICHPKLVYAKPDMAYRDNNHFCR 474

Query: 180 LIKRAVRKSKTGKVS-GQHLKYGEIRNGCYEKWEKLTGASLSMLDDGKWEKLTSASLSML 356
           L+ R V ++ TG     +HLK  +IR   ++KW+ LT +  S LD   + KL    LS L
Sbjct: 475 LMMREVLETTTGSAFWHRHLKRVQIRR--HKKWKTLTNSERSFLDRDMYFKLKWRELSSL 532


>ref|XP_023732060.1| uncharacterized protein LOC111879855 isoform X1 [Lactuca sativa]
 gb|PLY75192.1| hypothetical protein LSAT_2X123821 [Lactuca sativa]
          Length = 522

 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 41/105 (39%), Positives = 60/105 (57%), Gaps = 2/105 (1%)
 Frame = +3

Query: 3   RTRVPFP-ATNVETLSFESFSSNGLWDNLLLFDAFFSICQPMYVRAEGQLRLKVATYFLK 179
           RTR+ FP A NV+ L+F++ +   LW+    FDAFF IC P +V A    R +   +F +
Sbjct: 403 RTRLLFPPARNVQELAFQTVADECLWERSQFFDAFFEICHPKHVFARPDSRFRHNNHFCR 462

Query: 180 LIKRAVRKSKTGKVSGQH-LKYGEIRNGCYEKWEKLTGASLSMLD 311
           L+ R V + KT      H LK+ +IR   ++KW+ LT +  S LD
Sbjct: 463 LMLREVLEKKTRIAYWPHYLKHVQIRQYRHQKWKPLTVSHRSFLD 507


>gb|PLY97294.1| hypothetical protein LSAT_3X106860 [Lactuca sativa]
          Length = 336

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 39/105 (37%), Positives = 59/105 (56%), Gaps = 2/105 (1%)
 Frame = +3

Query: 3   RTRVPFP-ATNVETLSFESFSSNGLWDNLLLFDAFFSICQPMYVRAEGQLRLKVATYFLK 179
           +TR+ FP ATNV+ LSF +     LW+    FDAFF IC P +V A+    L+   +F +
Sbjct: 217 KTRLRFPPATNVQQLSFGTIGDECLWERSPFFDAFFEICHPKHVFAKPDAWLRQNNHFCR 276

Query: 180 LIKRAVRKSKTGKVS-GQHLKYGEIRNGCYEKWEKLTGASLSMLD 311
           ++ R V + KT       HLK+ +I+   ++ W+ LT +  S LD
Sbjct: 277 IMLREVLEKKTTTAKWPHHLKHVQIKQPLHKIWKTLTNSKKSFLD 321


>ref|XP_023732415.1| putative F-box/LRR-repeat protein At5g02700 [Lactuca sativa]
          Length = 530

 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 36/96 (37%), Positives = 51/96 (53%)
 Frame = +3

Query: 21  PATNVETLSFESFSSNGLWDNLLLFDAFFSICQPMYVRAEGQLRLKVATYFLKLIKRAVR 200
           PA NV+ L F +     LW+  L FDAFF IC P YV A+     +   +F +L+ R V 
Sbjct: 422 PAMNVQHLWFGTVDDECLWERSLFFDAFFEICHPKYVYAKPDSYFRQNNHFCRLMLREVL 481

Query: 201 KSKTGKVSGQHLKYGEIRNGCYEKWEKLTGASLSML 308
           +  T      +L++  IR   Y+KWE LT +  S+L
Sbjct: 482 EKNTTPYWPHYLEHVRIRRDRYQKWETLTNSHTSLL 517


>gb|PLY74936.1| hypothetical protein LSAT_9X12941 [Lactuca sativa]
          Length = 536

 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 36/96 (37%), Positives = 51/96 (53%)
 Frame = +3

Query: 21  PATNVETLSFESFSSNGLWDNLLLFDAFFSICQPMYVRAEGQLRLKVATYFLKLIKRAVR 200
           PA NV+ L F +     LW+  L FDAFF IC P YV A+     +   +F +L+ R V 
Sbjct: 428 PAMNVQHLWFGTVDDECLWERSLFFDAFFEICHPKYVYAKPDSYFRQNNHFCRLMLREVL 487

Query: 201 KSKTGKVSGQHLKYGEIRNGCYEKWEKLTGASLSML 308
           +  T      +L++  IR   Y+KWE LT +  S+L
Sbjct: 488 EKNTTPYWPHYLEHVRIRRDRYQKWETLTNSHTSLL 523


>ref|XP_023763265.1| uncharacterized protein LOC111911752 [Lactuca sativa]
 gb|PLY85886.1| hypothetical protein LSAT_5X48561 [Lactuca sativa]
          Length = 527

 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 39/106 (36%), Positives = 60/106 (56%), Gaps = 3/106 (2%)
 Frame = +3

Query: 3   RTRVPFP-ATNVETLSFESFSSNGLWDNLLLFDAFFSICQPMYVRAEGQLRLKVATYFLK 179
           RTR+  P ATN++ L FE+    GLW+    FDAFF IC P  V  +  +  K   +F +
Sbjct: 407 RTRLLLPPATNMQELWFETDEDEGLWERSPFFDAFFEICHPKQVFPQPDVSFKQNNHFCR 466

Query: 180 LIKRAVRKSKTGKVS--GQHLKYGEIRNGCYEKWEKLTGASLSMLD 311
           L+ R V + K  + +    +LK+ +IR   ++KW+ LT +  S+LD
Sbjct: 467 LMLREVLEKKNTRTAYWPHYLKHVQIRWDPHKKWKALTNSHRSLLD 512


>ref|XP_023768765.1| F-box/LRR-repeat protein At5g02910-like [Lactuca sativa]
 gb|PLY81753.1| hypothetical protein LSAT_3X23161 [Lactuca sativa]
          Length = 536

 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 36/100 (36%), Positives = 54/100 (54%), Gaps = 3/100 (3%)
 Frame = +3

Query: 21  PATNVETLSFESFSSNGLWDNLLLFDAFFSICQPMYVRAEGQLRLKVATYFLKLIKRAVR 200
           PATNV+ LSFE++    LW+    FDA   IC P  V A+  ++   + +F +L+ R V 
Sbjct: 422 PATNVQKLSFETWKDECLWERSPFFDAILEICHPKLVFAQPDMQFSHSNHFCRLMLREVL 481

Query: 201 KSKTGKVS---GQHLKYGEIRNGCYEKWEKLTGASLSMLD 311
           + KT         +LK+ +IR   Y+ W+ LT +  S LD
Sbjct: 482 EKKTTTTPLYWPHYLKHVQIRQSPYQTWKTLTNSHRSFLD 521


>ref|XP_023730411.1| putative F-box/LRR-repeat protein At3g28410 isoform X2 [Lactuca
           sativa]
 ref|XP_023730413.1| putative F-box/LRR-repeat protein At3g28410 isoform X2 [Lactuca
           sativa]
 gb|PLY76493.1| hypothetical protein LSAT_9X121120 [Lactuca sativa]
          Length = 527

 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 42/108 (38%), Positives = 58/108 (53%), Gaps = 5/108 (4%)
 Frame = +3

Query: 3   RTRVPFP-ATNVETLSFESFSSNGLWDNLLLFDAFFSICQPMYVRAEGQLRLKVATYFLK 179
           RTR+ FP ATNV+ L F++     +W+    FDAFF IC P  V A+         +F +
Sbjct: 405 RTRLMFPPATNVQELRFQTTEDECMWEQSPFFDAFFEICHPKCVYAKPDDHFNHNNHFCR 464

Query: 180 LIKRAVRKSK---TGKVSGQH-LKYGEIRNGCYEKWEKLTGASLSMLD 311
           L+ R V + K   TG V   H LK+ +I+    +KWE LT +  S LD
Sbjct: 465 LMLREVLEKKTTTTGIVYWPHYLKHVQIKQPLDQKWETLTNSHRSFLD 512


>ref|XP_023730410.1| putative F-box/LRR-repeat protein At3g28410 isoform X1 [Lactuca
           sativa]
          Length = 552

 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 42/108 (38%), Positives = 58/108 (53%), Gaps = 5/108 (4%)
 Frame = +3

Query: 3   RTRVPFP-ATNVETLSFESFSSNGLWDNLLLFDAFFSICQPMYVRAEGQLRLKVATYFLK 179
           RTR+ FP ATNV+ L F++     +W+    FDAFF IC P  V A+         +F +
Sbjct: 430 RTRLMFPPATNVQELRFQTTEDECMWEQSPFFDAFFEICHPKCVYAKPDDHFNHNNHFCR 489

Query: 180 LIKRAVRKSK---TGKVSGQH-LKYGEIRNGCYEKWEKLTGASLSMLD 311
           L+ R V + K   TG V   H LK+ +I+    +KWE LT +  S LD
Sbjct: 490 LMLREVLEKKTTTTGIVYWPHYLKHVQIKQPLDQKWETLTNSHRSFLD 537


>gb|PLY87227.1| hypothetical protein LSAT_4X154940 [Lactuca sativa]
          Length = 249

 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 41/104 (39%), Positives = 55/104 (52%), Gaps = 2/104 (1%)
 Frame = +3

Query: 3   RTRVPFP-ATNVETLSFESFSSNGLWDNLLLFDAFFSICQPMYVRAEGQLRLKVATYFLK 179
           R R+ FP ATNV+ L FE+     LW+    FDAFF IC P YV A+  +      +F +
Sbjct: 137 RRRLLFPPATNVQDLEFETSWDECLWERSPFFDAFFEICHPKYVYAKPDVMRPDNNHFCR 196

Query: 180 LIKRAVRKSKTG-KVSGQHLKYGEIRNGCYEKWEKLTGASLSML 308
           L+ R V  + TG      HLK  +IR   ++KW+ LT    S L
Sbjct: 197 LMMREVLDTTTGIAFWPHHLKDVQIRR--HKKWKTLTDCERSFL 238


>ref|XP_023740058.1| putative F-box/LRR-repeat protein At5g02700 [Lactuca sativa]
          Length = 514

 Score = 60.1 bits (144), Expect = 5e-08
 Identities = 36/104 (34%), Positives = 54/104 (51%), Gaps = 2/104 (1%)
 Frame = +3

Query: 3   RTRVPFP-ATNVETLSFESFSSNGLWDNLLLFDAFFSICQPMYVRAEGQLRLKVATYFLK 179
           R R+ FP A NV+ L FE+     LW+    FDAFF IC P ++ A      +   +F +
Sbjct: 398 RRRLLFPPAMNVQELEFETDEDECLWERSPFFDAFFEICHPKHIYARPDRHYRHNNHFCR 457

Query: 180 LIKRAV-RKSKTGKVSGQHLKYGEIRNGCYEKWEKLTGASLSML 308
           L+ R V  K KT  +    L++  IR   ++KW  LT +  ++L
Sbjct: 458 LMLREVLEKKKTTAIWPHRLQHVLIRPPPHKKWRTLTNSQRTLL 501


>gb|PLY68965.1| hypothetical protein LSAT_9X89481 [Lactuca sativa]
          Length = 569

 Score = 60.1 bits (144), Expect = 5e-08
 Identities = 36/104 (34%), Positives = 54/104 (51%), Gaps = 2/104 (1%)
 Frame = +3

Query: 3   RTRVPFP-ATNVETLSFESFSSNGLWDNLLLFDAFFSICQPMYVRAEGQLRLKVATYFLK 179
           R R+ FP A NV+ L FE+     LW+    FDAFF IC P ++ A      +   +F +
Sbjct: 453 RRRLLFPPAMNVQELEFETDEDECLWERSPFFDAFFEICHPKHIYARPDRHYRHNNHFCR 512

Query: 180 LIKRAV-RKSKTGKVSGQHLKYGEIRNGCYEKWEKLTGASLSML 308
           L+ R V  K KT  +    L++  IR   ++KW  LT +  ++L
Sbjct: 513 LMLREVLEKKKTTAIWPHRLQHVLIRPPPHKKWRTLTNSQRTLL 556


>ref|XP_023761562.1| uncharacterized protein LOC111909993 [Lactuca sativa]
 gb|PLY87216.1| hypothetical protein LSAT_4X154921 [Lactuca sativa]
          Length = 361

 Score = 59.7 bits (143), Expect = 6e-08
 Identities = 36/99 (36%), Positives = 54/99 (54%), Gaps = 2/99 (2%)
 Frame = +3

Query: 3   RTRVPFP-ATNVETLSFESFSSNGLWDNLLLFDAFFSICQPMYVRAEGQLRLKVATYFLK 179
           R R+ FP ATNV+ L FE+     LW+    FDAFF IC P  V A+  +  +   +F +
Sbjct: 265 RRRLLFPPATNVQELEFETVEDECLWERSPFFDAFFEICHPNLVYAKPDMTYRDNNHFCR 324

Query: 180 LIKRAVRKSKTGKVS-GQHLKYGEIRNGCYEKWEKLTGA 293
           L+ R V ++  G      HLK  +I+   ++KW+ LT +
Sbjct: 325 LMLREVLETTAGAAFWPHHLKRVQIKR--HKKWKTLTNS 361


>ref|XP_023773266.1| F-box/LRR-repeat protein At5g02910-like [Lactuca sativa]
 gb|PLY78202.1| hypothetical protein LSAT_4X131761 [Lactuca sativa]
          Length = 519

 Score = 58.5 bits (140), Expect = 2e-07
 Identities = 36/104 (34%), Positives = 53/104 (50%), Gaps = 2/104 (1%)
 Frame = +3

Query: 3   RTRVPFP-ATNVETLSFESFSSNGLWDNLLLFDAFFSICQPMYVRAEGQLRLKVATYFLK 179
           R R+ FP A NV+ L FE+     LW+    FDAFF IC P ++ A      +   +F +
Sbjct: 403 RRRLLFPPAMNVQELEFETDEDECLWERSPFFDAFFEICHPKHIYARPDRHYRHNNHFCR 462

Query: 180 LIKRAV-RKSKTGKVSGQHLKYGEIRNGCYEKWEKLTGASLSML 308
           L+ R V  K KT  +    L++  IR   ++KW  LT +  + L
Sbjct: 463 LMLREVLEKKKTTAIWPHRLQHVLIRPLPHKKWRTLTNSQRTFL 506


>ref|XP_023761561.1| uncharacterized protein LOC111909991 isoform X2 [Lactuca sativa]
          Length = 525

 Score = 55.8 bits (133), Expect = 1e-06
 Identities = 39/111 (35%), Positives = 54/111 (48%), Gaps = 1/111 (0%)
 Frame = +3

Query: 3   RTRVPFP-ATNVETLSFESFSSNGLWDNLLLFDAFFSICQPMYVRAEGQLRLKVATYFLK 179
           RTR+ FP ATNV+   F++     L D    FDAFF IC P +V A+  +  + + +F  
Sbjct: 416 RTRLLFPPATNVQKFEFQTVEDECLSDRSPFFDAFFEICHPKHVYAKRDMMDEYSNHFCS 475

Query: 180 LIKRAVRKSKTGKVSGQHLKYGEIRNGCYEKWEKLTGASLSMLDDGKWEKL 332
           L+   +    T      HLK  +IR   ++KWE LT    S L      KL
Sbjct: 476 LMLSEMTTGTT--FWSHHLKDVQIRR--HKKWETLTDCPRSFLHGNMHFKL 522


>ref|XP_023761560.1| uncharacterized protein LOC111909991 isoform X1 [Lactuca sativa]
 gb|PLY87206.1| hypothetical protein LSAT_4X154980 [Lactuca sativa]
          Length = 539

 Score = 55.8 bits (133), Expect = 1e-06
 Identities = 39/111 (35%), Positives = 54/111 (48%), Gaps = 1/111 (0%)
 Frame = +3

Query: 3   RTRVPFP-ATNVETLSFESFSSNGLWDNLLLFDAFFSICQPMYVRAEGQLRLKVATYFLK 179
           RTR+ FP ATNV+   F++     L D    FDAFF IC P +V A+  +  + + +F  
Sbjct: 430 RTRLLFPPATNVQKFEFQTVEDECLSDRSPFFDAFFEICHPKHVYAKRDMMDEYSNHFCS 489

Query: 180 LIKRAVRKSKTGKVSGQHLKYGEIRNGCYEKWEKLTGASLSMLDDGKWEKL 332
           L+   +    T      HLK  +IR   ++KWE LT    S L      KL
Sbjct: 490 LMLSEMTTGTT--FWSHHLKDVQIRR--HKKWETLTDCPRSFLHGNMHFKL 536


>gb|PLY70261.1| hypothetical protein LSAT_4X116140 [Lactuca sativa]
          Length = 511

 Score = 55.1 bits (131), Expect = 3e-06
 Identities = 37/109 (33%), Positives = 54/109 (49%), Gaps = 6/109 (5%)
 Frame = +3

Query: 3   RTRVPFP-ATNVETLSFESFSSNGLWDNLLLFDAFFSICQPMYVRAEGQLRLKVATYFLK 179
           RTR+  P A NV+ + F++      W+    FDAFF IC P ++       LK   +F K
Sbjct: 392 RTRLLLPPAINVQQVLFKTIGDECTWERSQFFDAFFEICHPDHISIWPDSMLKHNNHFCK 451

Query: 180 LIKRAV---RKSKTGKVS--GQHLKYGEIRNGCYEKWEKLTGASLSMLD 311
            + RAV    K+KT   S    +LK  +I+     +WE LT +  S L+
Sbjct: 452 FMLRAVMERNKNKTATTSYWPSYLKNVKIKQPHNREWETLTDSHTSFLE 500