BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Chrysanthemum21_contig00021563
         (1031 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_021977342.1| DNA topoisomerase 2-like [Helianthus annuus]...   358   e-109
ref|XP_022005320.1| DNA topoisomerase 2-like [Helianthus annuus]...   357   e-109
ref|XP_023759895.1| DNA topoisomerase 2 [Lactuca sativa]              342   e-103
gb|PLY88472.1| hypothetical protein LSAT_1X105720 [Lactuca sativa]    340   e-103
ref|XP_020113224.1| DNA topoisomerase 2-like [Ananas comosus]         311   6e-99
ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform ...   314   1e-93
ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform ...   314   2e-93
ref|XP_008791090.1| PREDICTED: DNA topoisomerase 2-like [Phoenix...   305   1e-92
gb|OAY66581.1| DNA topoisomerase 2 [Ananas comosus]                   311   1e-92
gb|EOY18139.1| Topoisomerase II isoform 3 [Theobroma cacao]           307   1e-91
gb|AQK54509.1| DNA topoisomerase 2 [Zea mays]                         289   1e-91
gb|EOY18138.1| DNA topoisomerase 2 isoform 2 [Theobroma cacao]        307   2e-91
gb|PON74229.1| DNA topoisomerase II-type [Parasponia andersonii]      306   5e-91
gb|EOY18137.1| DNA topoisomerase 2 isoform 1 [Theobroma cacao]        307   5e-91
gb|AQK54488.1| DNA topoisomerase 2 [Zea mays]                         289   8e-91
ref|XP_008779357.2| PREDICTED: DNA topoisomerase 2 [Phoenix dact...   305   2e-90
gb|PON46642.1| DNA topoisomerase II-type [Trema orientalis]           305   2e-90
ref|XP_021295966.1| DNA topoisomerase 2 [Herrania umbratica]          305   4e-90
ref|XP_010548805.1| PREDICTED: DNA topoisomerase 2 [Tarenaya has...   304   4e-90
ref|XP_008346962.1| PREDICTED: DNA topoisomerase 2-like [Malus d...   304   4e-90

>ref|XP_021977342.1| DNA topoisomerase 2-like [Helianthus annuus]
 gb|OTG37224.1| putative topoisomerase II [Helianthus annuus]
          Length = 1499

 Score =  358 bits (919), Expect = e-109
 Identities = 199/380 (52%), Positives = 247/380 (65%), Gaps = 44/380 (11%)
 Frame = +3

Query: 3    EADELCLNYLNDDGQSIEPEWFMPIIPMVLVNGIEGTVIGCSSFIPNYNPRAIIANLKRL 182
            +ADEL LNYLN+DGQSIEP WF+PIIPMVLVNG EG   G SSFIPNYNPR IIANLKRL
Sbjct: 803  KADELLLNYLNEDGQSIEPTWFIPIIPMVLVNGSEGIGTGWSSFIPNYNPRDIIANLKRL 862

Query: 183  LHGEAMLAMIPWYKGFKGDIEPASN--TEYTTKGKWGELEDGKTLRITELPVGRWTREYK 356
            L+GE M+ M PWYK FKG I+  ++  T YTT G + E ED  +L ITELP+ RWT+EYK
Sbjct: 863  LNGEQMVPMDPWYKWFKGTIQKTTSKDTGYTTVGVFEENEDNNSLNITELPIRRWTQEYK 922

Query: 357  QFLKAAQY-GKDQTPFIKAYTAHNDKTTVDFTISMSENQMNTAKKEEIWKKFKLTTTLST 533
            +FL+AA   GKD+ PFI+ Y AHND TTV F + M+ NQMN AK+E + KKFKLTTTLST
Sbjct: 923  EFLEAASLSGKDKEPFIEEYNAHNDDTTVHFEVVMTANQMNKAKEEGLLKKFKLTTTLST 982

Query: 534  ANMYLFDKDGAIKKYETPEEILRDFFCLRLDFYKKRMIALTDKLGKAILLLENKVRYINE 713
            +NM+LFD +G IKKY+TPE+IL DFF LRLD+Y+KR  AL  +LGKA L LENKVR+I E
Sbjct: 983  SNMHLFDANGVIKKYDTPEQILEDFFHLRLDYYEKRKNALLHELGKASLQLENKVRFIRE 1042

Query: 714  VKKGDIDIFNREDDAICADLKANGFKYLPKET--EPTIAGR------------------- 830
            V +G + + NR+   +CA+LK  G+  LPKE   E +IAG                    
Sbjct: 1043 VVEGTLVVSNRKKADLCAELKVKGYTPLPKEAVLEASIAGAVDHVEGSEETEEGSEEETA 1102

Query: 831  --------------------EEYDYLLSMTLASFTNKKIIEQFXXXXXXXXXXXXXXXXS 950
                                 EYDYLLSM + + T +K ++Q                 +
Sbjct: 1103 EMAVEEQKPSAGTASKTIPGTEYDYLLSMAIGTLTYEK-MQQLWHERDTKKAEFDELTNT 1161

Query: 951  TPESLWLRDLEALEQQLEEK 1010
              +SLWLRDL++L  QL+E+
Sbjct: 1162 PSKSLWLRDLDSLNNQLDEQ 1181


>ref|XP_022005320.1| DNA topoisomerase 2-like [Helianthus annuus]
 gb|OTF98638.1| putative DNA topoisomerase 2 [Helianthus annuus]
          Length = 1488

 Score =  357 bits (916), Expect = e-109
 Identities = 199/382 (52%), Positives = 246/382 (64%), Gaps = 46/382 (12%)
 Frame = +3

Query: 3    EADELCLNYLNDDGQSIEPEWFMPIIPMVLVNGIEGTVIGCSSFIPNYNPRAIIANLKRL 182
            +ADEL LN+LN+DGQSIEP W++PIIPMVLVNG EG   G SSF+PNYNPR IIANLKRL
Sbjct: 790  KADELLLNFLNEDGQSIEPTWYIPIIPMVLVNGSEGIGTGWSSFVPNYNPRDIIANLKRL 849

Query: 183  LHGEAMLAMIPWYKGFKGDIEPASN--TEYTTKGKWGELEDGKTLRITELPVGRWTREYK 356
            L+GE M+ M PWYK FKG I+  ++  T YTT G   E ED   L ITELP+ RWT+EYK
Sbjct: 850  LNGEPMVPMDPWYKWFKGTIQKTTSKDTGYTTIGNVEEKEDENALSITELPIRRWTQEYK 909

Query: 357  QFLKAAQY-GKDQTPFIKAYTAHNDKTTVDFTISMSENQMNTAKKEEIWKKFKLTTTLST 533
            +FL+AA   GKD+ PFI+ Y AHND TTV F + M+ +QMN AK+E + KKFKLTTTLST
Sbjct: 910  EFLEAASLSGKDKEPFIEEYNAHNDDTTVHFEVIMTASQMNKAKEEGLLKKFKLTTTLST 969

Query: 534  ANMYLFDKDGAIKKYETPEEILRDFFCLRLDFYKKRMIALTDKLGKAILLLENKVRYINE 713
            +NM+LFD +G IKKY+TPE+IL DFF LRLDFY+KR +AL  +LGKA L+LENKVR+I E
Sbjct: 970  SNMHLFDANGVIKKYDTPEQILEDFFHLRLDFYEKRKVALLHELGKASLILENKVRFIRE 1029

Query: 714  VKKGDIDIFNREDDAICADLKANGFKYLPKET--EPTIAGR------------------- 830
            V +G I + NR+   +CA+LK  GF  LPKE   E +IAG                    
Sbjct: 1030 VVEGTIVVSNRKKADLCAELKVKGFTPLPKEAVLEASIAGAVDHVEGSDETEEEEGSGSP 1089

Query: 831  ----------------------EEYDYLLSMTLASFTNKKIIEQFXXXXXXXXXXXXXXX 944
                                   EYDYLLSM + + T +K ++Q                
Sbjct: 1090 ADVAAVEEEKSHVGTASKTIPGTEYDYLLSMAIGTLTYEK-MKQLWHERDTKKAEFDELT 1148

Query: 945  XSTPESLWLRDLEALEQQLEEK 1010
             +  +SLWLRDL AL  QL+E+
Sbjct: 1149 NTPSKSLWLRDLNALSDQLDEQ 1170


>ref|XP_023759895.1| DNA topoisomerase 2 [Lactuca sativa]
          Length = 1508

 Score =  342 bits (877), Expect = e-103
 Identities = 191/372 (51%), Positives = 244/372 (65%), Gaps = 36/372 (9%)
 Frame = +3

Query: 3    EADELCLNYLNDDGQSIEPEWFMPIIPMVLVNGIEGTVIGCSSFIPNYNPRAIIANLKRL 182
            +ADEL LNYL++DGQSIEP W++PIIPMVLVNG EG   G S+F+PNYNPR IIANLKRL
Sbjct: 804  KADELLLNYLSEDGQSIEPTWYLPIIPMVLVNGSEGIGTGWSTFVPNYNPRDIIANLKRL 863

Query: 183  LHGEAMLAMIPWYKGFKGDIEPASN--TEYTTKGKWGELEDGKTLRITELPVGRWTREYK 356
            L+GE M+ M PWYK F+G I+  ++  T YTT G   E ED  TLRITELPV RWT+EYK
Sbjct: 864  LNGEEMVPMDPWYKWFRGTIQKTASKDTGYTTTGIVDEDEDENTLRITELPVRRWTQEYK 923

Query: 357  QFLKAAQY-GKDQTPFIKAYTAHNDKTTVDFTISMSENQMNTAKKEEIWKKFKLTTTLST 533
            +FL+ A   GKD+ PFI+ Y AHND TTV+F I M+ +QMN A++E + KKFKLTTTLST
Sbjct: 924  EFLEVASTAGKDKEPFIEEYNAHNDDTTVNFQIIMTADQMNKARQEGLLKKFKLTTTLST 983

Query: 534  ANMYLFDKDGAIKKYETPEEILRDFFCLRLDFYKKRMIALTDKLGKAILLLENKVRYINE 713
            +NM+LFD +G IKKY+TPE+IL DFF LRLD+Y++R  AL  +LGK  L LENKVR+I E
Sbjct: 984  SNMHLFDANGVIKKYDTPEQILEDFFPLRLDYYERRKTALLRELGKISLTLENKVRFIKE 1043

Query: 714  VKKGDIDIFNREDDAICADLKANGFKYLPKET--EPTIAGR------------------- 830
            V +G + + NR+   + A+L    +  LPKE   E +IAG                    
Sbjct: 1044 VVEGTLVVSNRKKADLYAELAKKKYTPLPKEAVIEASIAGAVDHVEGSEETEEEEASDVP 1103

Query: 831  ------------EEYDYLLSMTLASFTNKKIIEQFXXXXXXXXXXXXXXXXSTPESLWLR 974
                         EYDYLLSM +AS T +K ++Q                 +   SLWL+
Sbjct: 1104 IDVEAAAAXIPGTEYDYLLSMAIASLTYEK-MKQLWKERDEKKAEFDELTNTPSRSLWLK 1162

Query: 975  DLEALEQQLEEK 1010
            DL+ L++QL+E+
Sbjct: 1163 DLDDLDKQLDEQ 1174


>gb|PLY88472.1| hypothetical protein LSAT_1X105720 [Lactuca sativa]
          Length = 1508

 Score =  340 bits (873), Expect = e-103
 Identities = 190/372 (51%), Positives = 243/372 (65%), Gaps = 36/372 (9%)
 Frame = +3

Query: 3    EADELCLNYLNDDGQSIEPEWFMPIIPMVLVNGIEGTVIGCSSFIPNYNPRAIIANLKRL 182
            +ADEL LNYL++DGQSIEP W++PIIPMVLVNG EG   G S+F+PNYNPR IIANLKRL
Sbjct: 804  KADELLLNYLSEDGQSIEPTWYLPIIPMVLVNGSEGIGTGWSTFVPNYNPRDIIANLKRL 863

Query: 183  LHGEAMLAMIPWYKGFKGDIEPASN--TEYTTKGKWGELEDGKTLRITELPVGRWTREYK 356
            L+GE M+ M PWYK F+G I+  ++  T YTT G   E ED  TLRITELPV RWT+EYK
Sbjct: 864  LNGEEMVPMDPWYKWFRGTIQKTASKDTGYTTTGIVDEDEDENTLRITELPVRRWTQEYK 923

Query: 357  QFLKAAQY-GKDQTPFIKAYTAHNDKTTVDFTISMSENQMNTAKKEEIWKKFKLTTTLST 533
            +FL+ A   GKD+ PFI+ Y AHND TTV+F I M+ +QMN A++E + KKFKLTTTLST
Sbjct: 924  EFLEVASTAGKDKEPFIEEYNAHNDDTTVNFQIIMTADQMNKARQEGLLKKFKLTTTLST 983

Query: 534  ANMYLFDKDGAIKKYETPEEILRDFFCLRLDFYKKRMIALTDKLGKAILLLENKVRYINE 713
            +NM+LFD +G IKKY+TPE+IL DFF LRLD+Y++R   L  +LGK  L LENKVR+I E
Sbjct: 984  SNMHLFDANGVIKKYDTPEQILEDFFPLRLDYYERRKATLLRELGKISLTLENKVRFIKE 1043

Query: 714  VKKGDIDIFNREDDAICADLKANGFKYLPKET--EPTIAGR------------------- 830
            V +G + + NR+   + A+L    +  LPKE   E +IAG                    
Sbjct: 1044 VVEGTLVVSNRKKADLYAELAKKKYTPLPKEAVIEASIAGAVDHVEGSEETEEEEASDVP 1103

Query: 831  ------------EEYDYLLSMTLASFTNKKIIEQFXXXXXXXXXXXXXXXXSTPESLWLR 974
                         EYDYLLSM +AS T +K ++Q                 +   SLWL+
Sbjct: 1104 IDVEAAAAXIPGTEYDYLLSMAIASLTYEK-MKQLWKERDEKKAEFDELTNTPSRSLWLK 1162

Query: 975  DLEALEQQLEEK 1010
            DL+ L++QL+E+
Sbjct: 1163 DLDDLDKQLDEQ 1174


>ref|XP_020113224.1| DNA topoisomerase 2-like [Ananas comosus]
          Length = 536

 Score =  311 bits (798), Expect = 6e-99
 Identities = 171/363 (47%), Positives = 231/363 (63%), Gaps = 29/363 (7%)
 Frame = +3

Query: 9    DELCLNYLNDDGQSIEPEWFMPIIPMVLVNGIEGTVIGCSSFIPNYNPRAIIANLKRLLH 188
            D++ L+YLN+DGQSIEP W++PIIPMVL+NG EG   G SSF+PNYNPR IIAN++RLL+
Sbjct: 105  DDILLDYLNEDGQSIEPTWYIPIIPMVLINGSEGIGTGWSSFVPNYNPRDIIANVRRLLN 164

Query: 189  GEAMLAMIPWYKGFKGDIEPASNTE----YTTKGKWGELEDGKTLRITELPVGRWTREYK 356
             E M  M PWY+GFKG IE ++  E    YT  G   E+ D  TLRI ELPV RWT++YK
Sbjct: 165  DEPMQPMDPWYRGFKGLIEKSATKEAGVTYTITGIIEEV-DNTTLRIMELPVRRWTQDYK 223

Query: 357  QFLKAAQYGKDQT--PFIKAYTAHNDKTTVDFTISMSENQMNTAKKEEIWKKFKLTTTLS 530
            +FL+A   G D+   PFIK Y  HND TTV F ++++E  +N A +E + KKFKLTTT+ 
Sbjct: 224  EFLEALMTGNDKVKEPFIKDYREHNDDTTVHFEVTLTEENLNIALQEGLEKKFKLTTTIG 283

Query: 531  TANMYLFDKDGAIKKYETPEEILRDFFCLRLDFYKKRMIALTDKLGKAILLLENKVRYIN 710
            T NM+LFD +G IKKY+TPE+IL DFF LRL+FY+KR   L D L   +L L+NKVR+I 
Sbjct: 284  TTNMHLFDSNGVIKKYDTPEQILEDFFHLRLEFYEKRKKVLLDNLEMDLLKLDNKVRFIL 343

Query: 711  EVKKGDIDIFNREDDAICADLKANGFKYLPKET---EPTIAG------------------ 827
             V +G+I + NR+   +  +L   GF   PK++   +  I G                  
Sbjct: 344  GVVRGEIIVNNRKRAELFIELHQKGFTPFPKKSKGIDVAIVGATTEEEENEESPEMGKGG 403

Query: 828  --REEYDYLLSMTLASFTNKKIIEQFXXXXXXXXXXXXXXXXSTPESLWLRDLEALEQQL 1001
                +Y+YLLSM + + T +K +++                 +TP SLWL+DL+ALE++L
Sbjct: 404  VRASDYEYLLSMAIGTLTLEK-VQELCGERDKLESEVEELRKATPRSLWLKDLDALEREL 462

Query: 1002 EEK 1010
            EE+
Sbjct: 463  EEQ 465


>ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform X2 [Nelumbo nucifera]
          Length = 1503

 Score =  314 bits (805), Expect = 1e-93
 Identities = 174/366 (47%), Positives = 231/366 (63%), Gaps = 30/366 (8%)
 Frame = +3

Query: 3    EADELCLNYLNDDGQSIEPEWFMPIIPMVLVNGIEGTVIGCSSFIPNYNPRAIIANLKRL 182
            + D++ L+YLN+DGQSIEP W+MPIIP VLVNG EG   G SS+IPNYNPR I+AN+KRL
Sbjct: 806  KGDDILLDYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIKRL 865

Query: 183  LHGEAMLAMIPWYKGFKGDIEPASNTE----YTTKGKWGELEDGKTLRITELPVGRWTRE 350
            L+GE M  M PWYKGFKG IE  +  E    YT  G   E+ +  TLRITELP+ RWT++
Sbjct: 866  LNGEPMEPMDPWYKGFKGLIEKTATKEAGSSYTVSGIIEEINE-TTLRITELPIRRWTQD 924

Query: 351  YKQFLKAAQYGKDQT--PFIKAYTAHNDKTTVDFTISMSENQMNTAKKEEIWKKFKLTTT 524
            YK+FL++   G D+   PFIK Y  HND TTV F I +SE  +  AK+E + KKFKLTTT
Sbjct: 925  YKEFLESIMTGNDKIKEPFIKDYKEHNDDTTVHFEIILSEENLMMAKQEGLMKKFKLTTT 984

Query: 525  LSTANMYLFDKDGAIKKYETPEEILRDFFCLRLDFYKKRMIALTDKLGKAILLLENKVRY 704
            +ST+NM+LFD  G IKKY+ PE+IL +FF LRL+FY+KR     D L   +L L+NKVR+
Sbjct: 985  ISTSNMHLFDPKGTIKKYDNPEQILEEFFHLRLEFYEKRKKTQLDNLELDLLKLDNKVRF 1044

Query: 705  INEVKKGDIDIFNREDDAICADLKANGFKYLPKET---EPTIAGREE------------- 836
            I  V KG+I + NR+   +  +L+  GF   PK+T   E  +AG  E             
Sbjct: 1045 ILGVVKGEIIVSNRKRVDLFLELQQKGFTPFPKKTKALEAAVAGANEDGEENEENSEVVS 1104

Query: 837  --------YDYLLSMTLASFTNKKIIEQFXXXXXXXXXXXXXXXXSTPESLWLRDLEALE 992
                    Y+YLLSM + + T +K +++                 +TP SLW+ DL+ALE
Sbjct: 1105 SRGVRASDYEYLLSMAIGTLTLEK-VQELCSDRDKLNHEVEELRKATPNSLWMNDLDALE 1163

Query: 993  QQLEEK 1010
            ++L+E+
Sbjct: 1164 KELDEQ 1169


>ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform X1 [Nelumbo nucifera]
          Length = 1504

 Score =  314 bits (805), Expect = 2e-93
 Identities = 174/366 (47%), Positives = 231/366 (63%), Gaps = 30/366 (8%)
 Frame = +3

Query: 3    EADELCLNYLNDDGQSIEPEWFMPIIPMVLVNGIEGTVIGCSSFIPNYNPRAIIANLKRL 182
            + D++ L+YLN+DGQSIEP W+MPIIP VLVNG EG   G SS+IPNYNPR I+AN+KRL
Sbjct: 806  KGDDILLDYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIKRL 865

Query: 183  LHGEAMLAMIPWYKGFKGDIEPASNTE----YTTKGKWGELEDGKTLRITELPVGRWTRE 350
            L+GE M  M PWYKGFKG IE  +  E    YT  G   E+ +  TLRITELP+ RWT++
Sbjct: 866  LNGEPMEPMDPWYKGFKGLIEKTATKEAGSSYTVSGIIEEINE-TTLRITELPIRRWTQD 924

Query: 351  YKQFLKAAQYGKDQT--PFIKAYTAHNDKTTVDFTISMSENQMNTAKKEEIWKKFKLTTT 524
            YK+FL++   G D+   PFIK Y  HND TTV F I +SE  +  AK+E + KKFKLTTT
Sbjct: 925  YKEFLESIMTGNDKIKEPFIKDYKEHNDDTTVHFEIILSEENLMMAKQEGLMKKFKLTTT 984

Query: 525  LSTANMYLFDKDGAIKKYETPEEILRDFFCLRLDFYKKRMIALTDKLGKAILLLENKVRY 704
            +ST+NM+LFD  G IKKY+ PE+IL +FF LRL+FY+KR     D L   +L L+NKVR+
Sbjct: 985  ISTSNMHLFDPKGTIKKYDNPEQILEEFFHLRLEFYEKRKKTQLDNLELDLLKLDNKVRF 1044

Query: 705  INEVKKGDIDIFNREDDAICADLKANGFKYLPKET---EPTIAGREE------------- 836
            I  V KG+I + NR+   +  +L+  GF   PK+T   E  +AG  E             
Sbjct: 1045 ILGVVKGEIIVSNRKRVDLFLELQQKGFTPFPKKTKALEAAVAGANEDGEENEENSEVVS 1104

Query: 837  --------YDYLLSMTLASFTNKKIIEQFXXXXXXXXXXXXXXXXSTPESLWLRDLEALE 992
                    Y+YLLSM + + T +K +++                 +TP SLW+ DL+ALE
Sbjct: 1105 SRGVRASDYEYLLSMAIGTLTLEK-VQELCSDRDKLNHEVEELRKATPNSLWMNDLDALE 1163

Query: 993  QQLEEK 1010
            ++L+E+
Sbjct: 1164 KELDEQ 1169


>ref|XP_008791090.1| PREDICTED: DNA topoisomerase 2-like [Phoenix dactylifera]
          Length = 896

 Score =  305 bits (780), Expect = 1e-92
 Identities = 169/364 (46%), Positives = 229/364 (62%), Gaps = 30/364 (8%)
 Frame = +3

Query: 9    DELCLNYLNDDGQSIEPEWFMPIIPMVLVNGIEGTVIGCSSFIPNYNPRAIIANLKRLLH 188
            D++ L+YLN+DGQSIEP W+MPIIPMVLVNG EG   G SSF+PNYNPR I+AN++RLL+
Sbjct: 236  DDILLDYLNEDGQSIEPTWYMPIIPMVLVNGSEGIGTGWSSFVPNYNPRDIVANVRRLLN 295

Query: 189  GEAMLAMIPWYKGFKGDIEPASNTE----YTTKGKWGELEDGKTLRITELPVGRWTREYK 356
            GE M  M PWY+GFKG IE +++ E    YT  G   E ED  TLRITELP+ RWT++YK
Sbjct: 296  GEPMQPMDPWYRGFKGLIEKSASKEAGVTYTVTGLSQE-EDNTTLRITELPIRRWTQDYK 354

Query: 357  QFLKAAQYGKDQT--PFIKAYTAHNDKTTVDFTISMSENQMNTAKKEEIWKKFKLTTTLS 530
            +FL++   G D+   P IK Y   ND  +V F I ++E ++  A++E I KKFKLTTT+ 
Sbjct: 355  EFLESMMTGNDKIKEPLIKDYREQNDDVSVHFEIILTEEKLKMAREEGIEKKFKLTTTIG 414

Query: 531  TANMYLFDKDGAIKKYETPEEILRDFFCLRLDFYKKRMIALTDKLGKAILLLENKVRYIN 710
            T NM+LFD  G IKKY+TPE+IL DFF LRL+FY KR  AL D L   +L L+NKVR+I 
Sbjct: 415  TTNMHLFDSKGVIKKYDTPEQILEDFFHLRLEFYGKRKKALLDNLELDLLKLDNKVRFIL 474

Query: 711  EVKKGDIDIFNREDDAICADLKANGFKYLPKET---EPTIAG------------------ 827
             V +G+I + NR+   +  +L+  GF   PK++   +  IAG                  
Sbjct: 475  GVVRGEIIVNNRKRADLFLELQQKGFAPFPKKSKGIDAAIAGATVEEDGNEESPEVVNGG 534

Query: 828  ---REEYDYLLSMTLASFTNKKIIEQFXXXXXXXXXXXXXXXXSTPESLWLRDLEALEQQ 998
                 +Y+YLLSM + + T +K +++                 S+P  LW RDL+A E++
Sbjct: 535  GAKATDYEYLLSMAIGTLTWEK-VQELCAERKKLEDEVEELRKSSPRDLWTRDLDAFERE 593

Query: 999  LEEK 1010
            L+E+
Sbjct: 594  LDEQ 597


>gb|OAY66581.1| DNA topoisomerase 2 [Ananas comosus]
          Length = 1476

 Score =  311 bits (798), Expect = 1e-92
 Identities = 171/363 (47%), Positives = 231/363 (63%), Gaps = 29/363 (7%)
 Frame = +3

Query: 9    DELCLNYLNDDGQSIEPEWFMPIIPMVLVNGIEGTVIGCSSFIPNYNPRAIIANLKRLLH 188
            D++ L+YLN+DGQSIEP W++PIIPMVL+NG EG   G SSF+PNYNPR IIAN++RLL+
Sbjct: 810  DDILLDYLNEDGQSIEPTWYIPIIPMVLINGSEGIGTGWSSFVPNYNPRDIIANVRRLLN 869

Query: 189  GEAMLAMIPWYKGFKGDIEPASNTE----YTTKGKWGELEDGKTLRITELPVGRWTREYK 356
             E M  M PWY+GFKG IE ++  E    YT  G   E+ D  TLRI ELPV RWT++YK
Sbjct: 870  DEPMQPMDPWYRGFKGLIEKSATKEAGVTYTITGIIEEV-DNATLRIMELPVRRWTQDYK 928

Query: 357  QFLKAAQYGKDQT--PFIKAYTAHNDKTTVDFTISMSENQMNTAKKEEIWKKFKLTTTLS 530
            +FL+A   G D+   PFIK Y  HND TTV F ++++E  +N A +E + KKFKLTTT+ 
Sbjct: 929  EFLEALMTGNDKVKEPFIKDYREHNDDTTVHFEVTLTEENLNIALQEGLEKKFKLTTTIG 988

Query: 531  TANMYLFDKDGAIKKYETPEEILRDFFCLRLDFYKKRMIALTDKLGKAILLLENKVRYIN 710
            T NM+LFD +G IKKY+TPE+IL DFF LRL+FY+KR   L D L   +L L+NKVR+I 
Sbjct: 989  TTNMHLFDSNGVIKKYDTPEQILEDFFHLRLEFYEKRKKVLLDNLEMDLLKLDNKVRFIL 1048

Query: 711  EVKKGDIDIFNREDDAICADLKANGFKYLPKET---EPTIAG------------------ 827
             V +G+I + NR+   +  +L   GF   PK++   +  I G                  
Sbjct: 1049 GVVRGEIIVNNRKRAELFIELHQKGFTPFPKKSKGIDVAIVGATTEEEENEESPEMGKGG 1108

Query: 828  --REEYDYLLSMTLASFTNKKIIEQFXXXXXXXXXXXXXXXXSTPESLWLRDLEALEQQL 1001
                +Y+YLLSM + + T +K +++                 +TP SLWL+DL+ALE++L
Sbjct: 1109 VRASDYEYLLSMAIGTLTLEK-VQELCGERDKLESEVEELRKATPRSLWLKDLDALEREL 1167

Query: 1002 EEK 1010
            EE+
Sbjct: 1168 EEQ 1170


>gb|EOY18139.1| Topoisomerase II isoform 3 [Theobroma cacao]
          Length = 1244

 Score =  307 bits (786), Expect = 1e-91
 Identities = 170/361 (47%), Positives = 233/361 (64%), Gaps = 27/361 (7%)
 Frame = +3

Query: 9    DELCLNYLNDDGQSIEPEWFMPIIPMVLVNGIEGTVIGCSSFIPNYNPRAIIANLKRLLH 188
            D+  L+YLN+DGQSIEP W++PIIPMVLVNG EG   G SS+IPNYNPR I+AN++RLL+
Sbjct: 802  DDGLLDYLNEDGQSIEPIWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLN 861

Query: 189  GEAMLAMIPWYKGFKGDIEPASNTE----YTTKGKWGELEDGKTLRITELPVGRWTREYK 356
            GE M  M PWY+GFKG+IE  ++ E    YT  G   E+++  TLRITELPV RWT++Y+
Sbjct: 862  GEQMEPMHPWYRGFKGNIEKTASKEAGVTYTITGIIEEVDE-TTLRITELPVRRWTQDYR 920

Query: 357  QFLKAAQYGKDQTPFIKAYTAHNDKTTVDFTISMSENQMNTAKKEEIWKKFKLTTTLSTA 536
            +FL++   G D  PFIK +  ++D TTV+F + ++E  M  AK+E + KKFKLTTT+ST+
Sbjct: 921  EFLESIITGND--PFIKEFRQYSDDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTS 978

Query: 537  NMYLFDKDGAIKKYETPEEILRDFFCLRLDFYKKRMIALTDKLGKAILLLENKVRYINEV 716
            NM+LFD  G IKKY+TPE+IL +FF LR +FY+KR   L D L   +L +ENKVR+I  V
Sbjct: 979  NMHLFDSKGMIKKYDTPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGV 1038

Query: 717  KKGDIDIFNREDDAICADLKANGFKYLPKE---TEPTIAG-------------------- 827
             KG+I + NR+   +  +L+  GF   PK+    E  +AG                    
Sbjct: 1039 VKGEIIVNNRKRADLFLELQTKGFTPFPKKAKTVEVAVAGATDDTEETEENSEVSAKGLQ 1098

Query: 828  REEYDYLLSMTLASFTNKKIIEQFXXXXXXXXXXXXXXXXSTPESLWLRDLEALEQQLEE 1007
              +YDYLLSM + S T +K +++                 +TP+SLWL+DL+ LE QL+E
Sbjct: 1099 ASDYDYLLSMAIGSLTLEK-VQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDE 1157

Query: 1008 K 1010
            +
Sbjct: 1158 Q 1158


>gb|AQK54509.1| DNA topoisomerase 2 [Zea mays]
          Length = 419

 Score =  289 bits (739), Expect = 1e-91
 Identities = 162/360 (45%), Positives = 221/360 (61%), Gaps = 28/360 (7%)
 Frame = +3

Query: 9    DELCLNYLNDDGQSIEPEWFMPIIPMVLVNGIEGTVIGCSSFIPNYNPRAIIANLKRLLH 188
            D++ LNYLN+DGQSIEP W+MPI+PMVLVNG EG   G S++IPNYNPR I+ANL+RLL+
Sbjct: 38   DDILLNYLNEDGQSIEPTWYMPILPMVLVNGSEGIGTGWSTYIPNYNPRDILANLRRLLN 97

Query: 189  GEAMLAMIPWYKGFKGDIEPASNTE-----YTTKGKWGELEDGKTLRITELPVGRWTREY 353
            GE+ + M PWY+GFKG IE   NT+     YT  G   E+ D  TLRITELP+ RWT++Y
Sbjct: 98   GESTVPMHPWYRGFKGSIEKTVNTKVAGSTYTVTGII-EVLDNTTLRITELPIRRWTQDY 156

Query: 354  KQFLKAA---QYGKDQTPFIKAYTAHNDKTTVDFTISMSENQMNTAKKEEIWKKFKLTTT 524
            K +L++       KD+ PFI+  T   D   V    ++SE  MN A +E + KKFKLTTT
Sbjct: 157  KDYLESLAPDTKNKDKVPFIEDVTCQGDNEDVYIQFTLSEKNMNIAMEEGLVKKFKLTTT 216

Query: 525  LSTANMYLFDKDGAIKKYETPEEILRDFFCLRLDFYKKRMIALTDKLGKAILLLENKVRY 704
            + T+NM+LFD DG I+KY+TPE+IL +F  LRL+FY KR  AL   +   +  LENKVR+
Sbjct: 217  IGTSNMHLFDSDGKIRKYDTPEQILEEFCHLRLEFYCKRKEALLKSIKLDLKKLENKVRF 276

Query: 705  INEVKKGDIDIFNREDDAICADLKANGFKYLPK------------------ETEPTIAGR 830
            I  V   +I + NR+   +  +L+   F   PK                  E  P  AG 
Sbjct: 277  IRCVVDNEIIVNNRKRADLFLELRQKNFDPFPKKKKRAEPAAVGALEEEENEESPEAAGA 336

Query: 831  E--EYDYLLSMTLASFTNKKIIEQFXXXXXXXXXXXXXXXXSTPESLWLRDLEALEQQLE 1004
            E  +Y+YLLSM++ + T +K I++                  +P+SLWL+DL+A E++L+
Sbjct: 337  EPSDYEYLLSMSIGTLTLEK-IQELNAEKQKLVDDVEELENMSPKSLWLKDLDAFEKELD 395


>gb|EOY18138.1| DNA topoisomerase 2 isoform 2 [Theobroma cacao]
          Length = 1285

 Score =  307 bits (786), Expect = 2e-91
 Identities = 170/361 (47%), Positives = 233/361 (64%), Gaps = 27/361 (7%)
 Frame = +3

Query: 9    DELCLNYLNDDGQSIEPEWFMPIIPMVLVNGIEGTVIGCSSFIPNYNPRAIIANLKRLLH 188
            D+  L+YLN+DGQSIEP W++PIIPMVLVNG EG   G SS+IPNYNPR I+AN++RLL+
Sbjct: 613  DDGLLDYLNEDGQSIEPIWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLN 672

Query: 189  GEAMLAMIPWYKGFKGDIEPASNTE----YTTKGKWGELEDGKTLRITELPVGRWTREYK 356
            GE M  M PWY+GFKG+IE  ++ E    YT  G   E+++  TLRITELPV RWT++Y+
Sbjct: 673  GEQMEPMHPWYRGFKGNIEKTASKEAGVTYTITGIIEEVDE-TTLRITELPVRRWTQDYR 731

Query: 357  QFLKAAQYGKDQTPFIKAYTAHNDKTTVDFTISMSENQMNTAKKEEIWKKFKLTTTLSTA 536
            +FL++   G D  PFIK +  ++D TTV+F + ++E  M  AK+E + KKFKLTTT+ST+
Sbjct: 732  EFLESIITGND--PFIKEFRQYSDDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTS 789

Query: 537  NMYLFDKDGAIKKYETPEEILRDFFCLRLDFYKKRMIALTDKLGKAILLLENKVRYINEV 716
            NM+LFD  G IKKY+TPE+IL +FF LR +FY+KR   L D L   +L +ENKVR+I  V
Sbjct: 790  NMHLFDSKGMIKKYDTPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGV 849

Query: 717  KKGDIDIFNREDDAICADLKANGFKYLPKE---TEPTIAG-------------------- 827
             KG+I + NR+   +  +L+  GF   PK+    E  +AG                    
Sbjct: 850  VKGEIIVNNRKRADLFLELQTKGFTPFPKKAKTVEVAVAGATDDTEETEENSEVSAKGLQ 909

Query: 828  REEYDYLLSMTLASFTNKKIIEQFXXXXXXXXXXXXXXXXSTPESLWLRDLEALEQQLEE 1007
              +YDYLLSM + S T +K +++                 +TP+SLWL+DL+ LE QL+E
Sbjct: 910  ASDYDYLLSMAIGSLTLEK-VQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDE 968

Query: 1008 K 1010
            +
Sbjct: 969  Q 969


>gb|PON74229.1| DNA topoisomerase II-type [Parasponia andersonii]
          Length = 1397

 Score =  306 bits (785), Expect = 5e-91
 Identities = 165/363 (45%), Positives = 232/363 (63%), Gaps = 30/363 (8%)
 Frame = +3

Query: 9    DELCLNYLNDDGQSIEPEWFMPIIPMVLVNGIEGTVIGCSSFIPNYNPRAIIANLKRLLH 188
            D++ L+Y+++DGQSIEP W+MPIIP VLVNG EG   G SS+IPNYNPR I+AN++RLL+
Sbjct: 776  DDILLDYMDEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLN 835

Query: 189  GEAMLAMIPWYKGFKGDIEPASN---TEYTTKGKWGELEDGKTLRITELPVGRWTREYKQ 359
            G+ M+ M PWY+GFKG IE +S      Y   G   E+ +  T+RITELP+ RWT++YK+
Sbjct: 836  GDEMVPMDPWYRGFKGTIERSSKEGGASYIVSGIIEEVNE-TTVRITELPIRRWTQDYKE 894

Query: 360  FLKAAQYGKDQT--PFIKAYTAHNDKTTVDFTISMSENQMNTAKKEEIWKKFKLTTTLST 533
            FL++   G ++   PFI+ +T H+D +TVD  + + E  +  AK+E + KKFKLTT++ST
Sbjct: 895  FLESISQGNEKAKDPFIEGFTQHSDHSTVDILVHLPEENLMAAKQEGLLKKFKLTTSIST 954

Query: 534  ANMYLFDKDGAIKKYETPEEILRDFFCLRLDFYKKRMIALTDKLGKAILLLENKVRYINE 713
             NM+LFD +G IKKY+TPE+IL +FF LRL+FY+KR   L D L   +L LENKVR+I  
Sbjct: 955  TNMHLFDANGVIKKYDTPEQILEEFFHLRLEFYEKRKKVLLDNLELDLLKLENKVRFILG 1014

Query: 714  VKKGDIDIFNREDDAICADLKANGFKYLPKET---EPTIAGREE---------------- 836
            V KG+I + NR+   +  +L+  GF   PK+T   EP +AG  E                
Sbjct: 1015 VVKGEIIVNNRKRADLFVELQKKGFTPFPKKTKSVEPEVAGATEETEDTEDNSNAEAAAT 1074

Query: 837  ------YDYLLSMTLASFTNKKIIEQFXXXXXXXXXXXXXXXXSTPESLWLRDLEALEQQ 998
                  Y+YLLSM + + T +K ++                  +TP+SLW+RDL+AL+ Q
Sbjct: 1075 EVRISDYEYLLSMAIGTLTLEK-VQALLAERDKLNNEVDELRKATPKSLWVRDLDALDTQ 1133

Query: 999  LEE 1007
            L+E
Sbjct: 1134 LDE 1136


>gb|EOY18137.1| DNA topoisomerase 2 isoform 1 [Theobroma cacao]
          Length = 1473

 Score =  307 bits (786), Expect = 5e-91
 Identities = 170/361 (47%), Positives = 233/361 (64%), Gaps = 27/361 (7%)
 Frame = +3

Query: 9    DELCLNYLNDDGQSIEPEWFMPIIPMVLVNGIEGTVIGCSSFIPNYNPRAIIANLKRLLH 188
            D+  L+YLN+DGQSIEP W++PIIPMVLVNG EG   G SS+IPNYNPR I+AN++RLL+
Sbjct: 802  DDGLLDYLNEDGQSIEPIWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLN 861

Query: 189  GEAMLAMIPWYKGFKGDIEPASNTE----YTTKGKWGELEDGKTLRITELPVGRWTREYK 356
            GE M  M PWY+GFKG+IE  ++ E    YT  G   E+++  TLRITELPV RWT++Y+
Sbjct: 862  GEQMEPMHPWYRGFKGNIEKTASKEAGVTYTITGIIEEVDE-TTLRITELPVRRWTQDYR 920

Query: 357  QFLKAAQYGKDQTPFIKAYTAHNDKTTVDFTISMSENQMNTAKKEEIWKKFKLTTTLSTA 536
            +FL++   G D  PFIK +  ++D TTV+F + ++E  M  AK+E + KKFKLTTT+ST+
Sbjct: 921  EFLESIITGND--PFIKEFRQYSDDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTS 978

Query: 537  NMYLFDKDGAIKKYETPEEILRDFFCLRLDFYKKRMIALTDKLGKAILLLENKVRYINEV 716
            NM+LFD  G IKKY+TPE+IL +FF LR +FY+KR   L D L   +L +ENKVR+I  V
Sbjct: 979  NMHLFDSKGMIKKYDTPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGV 1038

Query: 717  KKGDIDIFNREDDAICADLKANGFKYLPKE---TEPTIAG-------------------- 827
             KG+I + NR+   +  +L+  GF   PK+    E  +AG                    
Sbjct: 1039 VKGEIIVNNRKRADLFLELQTKGFTPFPKKAKTVEVAVAGATDDTEETEENSEVSAKGLQ 1098

Query: 828  REEYDYLLSMTLASFTNKKIIEQFXXXXXXXXXXXXXXXXSTPESLWLRDLEALEQQLEE 1007
              +YDYLLSM + S T +K +++                 +TP+SLWL+DL+ LE QL+E
Sbjct: 1099 ASDYDYLLSMAIGSLTLEK-VQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDE 1157

Query: 1008 K 1010
            +
Sbjct: 1158 Q 1158


>gb|AQK54488.1| DNA topoisomerase 2 [Zea mays]
          Length = 480

 Score =  289 bits (739), Expect = 8e-91
 Identities = 162/360 (45%), Positives = 221/360 (61%), Gaps = 28/360 (7%)
 Frame = +3

Query: 9    DELCLNYLNDDGQSIEPEWFMPIIPMVLVNGIEGTVIGCSSFIPNYNPRAIIANLKRLLH 188
            D++ LNYLN+DGQSIEP W+MPI+PMVLVNG EG   G S++IPNYNPR I+ANL+RLL+
Sbjct: 52   DDILLNYLNEDGQSIEPTWYMPILPMVLVNGSEGIGTGWSTYIPNYNPRDILANLRRLLN 111

Query: 189  GEAMLAMIPWYKGFKGDIEPASNTE-----YTTKGKWGELEDGKTLRITELPVGRWTREY 353
            GE+ + M PWY+GFKG IE   NT+     YT  G   E+ D  TLRITELP+ RWT++Y
Sbjct: 112  GESTVPMHPWYRGFKGSIEKTVNTKVAGSTYTVTGII-EVLDNTTLRITELPIRRWTQDY 170

Query: 354  KQFLKAA---QYGKDQTPFIKAYTAHNDKTTVDFTISMSENQMNTAKKEEIWKKFKLTTT 524
            K +L++       KD+ PFI+  T   D   V    ++SE  MN A +E + KKFKLTTT
Sbjct: 171  KDYLESLAPDTKNKDKVPFIEDVTCQGDNEDVYIQFTLSEKNMNIAMEEGLVKKFKLTTT 230

Query: 525  LSTANMYLFDKDGAIKKYETPEEILRDFFCLRLDFYKKRMIALTDKLGKAILLLENKVRY 704
            + T+NM+LFD DG I+KY+TPE+IL +F  LRL+FY KR  AL   +   +  LENKVR+
Sbjct: 231  IGTSNMHLFDSDGKIRKYDTPEQILEEFCHLRLEFYCKRKEALLKSIKLDLKKLENKVRF 290

Query: 705  INEVKKGDIDIFNREDDAICADLKANGFKYLPK------------------ETEPTIAGR 830
            I  V   +I + NR+   +  +L+   F   PK                  E  P  AG 
Sbjct: 291  IRCVVDNEIIVNNRKRADLFLELRQKNFDPFPKKKKRAEPAAVGALEEEENEESPEAAGA 350

Query: 831  E--EYDYLLSMTLASFTNKKIIEQFXXXXXXXXXXXXXXXXSTPESLWLRDLEALEQQLE 1004
            E  +Y+YLLSM++ + T +K I++                  +P+SLWL+DL+A E++L+
Sbjct: 351  EPSDYEYLLSMSIGTLTLEK-IQELNAEKQKLVDDVEELENMSPKSLWLKDLDAFEKELD 409


>ref|XP_008779357.2| PREDICTED: DNA topoisomerase 2 [Phoenix dactylifera]
          Length = 1378

 Score =  305 bits (781), Expect = 2e-90
 Identities = 165/358 (46%), Positives = 227/358 (63%), Gaps = 25/358 (6%)
 Frame = +3

Query: 9    DELCLNYLNDDGQSIEPEWFMPIIPMVLVNGIEGTVIGCSSFIPNYNPRAIIANLKRLLH 188
            D++ L+YLN+DGQSIEP W+MPIIP+VLVNG EG   G SSF+PNYNPR I+AN++RLL+
Sbjct: 710  DDMLLDYLNEDGQSIEPTWYMPIIPLVLVNGSEGIGTGWSSFVPNYNPRDIVANVRRLLN 769

Query: 189  GEAMLAMIPWYKGFKGDIEPASNTE----YTTKGKWGELEDGKTLRITELPVGRWTREYK 356
             E M  M PWY+GFKG IE ++  E    YT  G   E+ D  TLRITELP+ RWT++YK
Sbjct: 770  DEPMQPMDPWYRGFKGLIEKSATKEAGVTYTITGLIEEV-DSTTLRITELPIRRWTQDYK 828

Query: 357  QFLKAAQYGKDQT--PFIKAYTAHNDKTTVDFTISMSENQMNTAKKEEIWKKFKLTTTLS 530
            +FL++   G D+   PFIK Y  HND   V F I ++E ++  AK+E + +KFKLTTT+S
Sbjct: 829  EFLESMMTGNDKIKEPFIKDYREHNDDINVHFEIILTEEKLKMAKEEGLERKFKLTTTIS 888

Query: 531  TANMYLFDKDGAIKKYETPEEILRDFFCLRLDFYKKRMIALTDKLGKAILLLENKVRYIN 710
            T NM+LFD +G IKKY+TPE+IL DFF LRL++Y KR   L D L   +L L+NKVR+I 
Sbjct: 889  TTNMHLFDSEGVIKKYDTPEQILEDFFHLRLEYYAKRKKVLLDNLEMDLLKLDNKVRFIL 948

Query: 711  EVKKGDIDIFNREDDAICADLKANGFKYLPK------------------ETEPTIAGR-E 833
             V +G+I + NR+   +  +L+  GF   PK                  E  P +A R  
Sbjct: 949  GVVRGEIIVSNRKRADLFLELQQKGFTPFPKKSKGIDAAIAGATEEDDNEESPEVAARAT 1008

Query: 834  EYDYLLSMTLASFTNKKIIEQFXXXXXXXXXXXXXXXXSTPESLWLRDLEALEQQLEE 1007
            +Y+YLLSM + + T +K +++                 S+P  LW++DL+  E++L+E
Sbjct: 1009 DYEYLLSMAIGTLTWEK-VQELCADRKKLEGEVEELKKSSPRDLWMKDLDDFERELDE 1065


>gb|PON46642.1| DNA topoisomerase II-type [Trema orientalis]
          Length = 1397

 Score =  305 bits (781), Expect = 2e-90
 Identities = 165/363 (45%), Positives = 231/363 (63%), Gaps = 30/363 (8%)
 Frame = +3

Query: 9    DELCLNYLNDDGQSIEPEWFMPIIPMVLVNGIEGTVIGCSSFIPNYNPRAIIANLKRLLH 188
            D++ L+YL++DGQSIEP W+MPIIP VLVNG EG   G SS+IPNYNPR I+AN++RLL+
Sbjct: 776  DDILLDYLDEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLN 835

Query: 189  GEAMLAMIPWYKGFKGDIEPASN---TEYTTKGKWGELEDGKTLRITELPVGRWTREYKQ 359
            G+ M+ M PWY+GFKG IE +S      Y   G   E+ +  T+RITELP+ RWT++YK+
Sbjct: 836  GDEMVPMDPWYRGFKGTIERSSKEGGASYIVSGIIEEVNE-TTVRITELPIRRWTQDYKE 894

Query: 360  FLKAAQYGKDQT--PFIKAYTAHNDKTTVDFTISMSENQMNTAKKEEIWKKFKLTTTLST 533
            FL++   G ++   PFI+ +T H+D +TVD  + + E  +  AK+E + KK KLTT++ST
Sbjct: 895  FLESISQGNEKAKDPFIEGFTQHSDHSTVDILVHLPEENLMAAKQEGLLKKLKLTTSIST 954

Query: 534  ANMYLFDKDGAIKKYETPEEILRDFFCLRLDFYKKRMIALTDKLGKAILLLENKVRYINE 713
             NM+LFD +G IKKY+TPE+IL +FF LRL+FY+KR   L D L   +L LENKVR+I  
Sbjct: 955  TNMHLFDANGVIKKYDTPEQILEEFFHLRLEFYEKRKKVLLDNLELDLLKLENKVRFILG 1014

Query: 714  VKKGDIDIFNREDDAICADLKANGFKYLPKET---EPTIAGREE---------------- 836
            V KG+I + NR+   +  +L+  GF   PK+T   EP +AG  E                
Sbjct: 1015 VVKGEIIVNNRKRADLFVELQKKGFTPFPKKTKSVEPEVAGATEETEDTEDNSNAEAAAT 1074

Query: 837  ------YDYLLSMTLASFTNKKIIEQFXXXXXXXXXXXXXXXXSTPESLWLRDLEALEQQ 998
                  Y+YLLSM + + T +K ++                  +TP+SLW+RDL+AL+ Q
Sbjct: 1075 EVRISDYEYLLSMAIGTLTLEK-VQALLAERDKLNNEVDELRKATPKSLWVRDLDALDTQ 1133

Query: 999  LEE 1007
            L+E
Sbjct: 1134 LDE 1136


>ref|XP_021295966.1| DNA topoisomerase 2 [Herrania umbratica]
          Length = 1475

 Score =  305 bits (780), Expect = 4e-90
 Identities = 169/361 (46%), Positives = 232/361 (64%), Gaps = 27/361 (7%)
 Frame = +3

Query: 9    DELCLNYLNDDGQSIEPEWFMPIIPMVLVNGIEGTVIGCSSFIPNYNPRAIIANLKRLLH 188
            D+  L+YLN+DGQSIEP W++PIIPMVLVNG EG   G SS+IPNYNPR I+AN++RLL+
Sbjct: 802  DDGVLDYLNEDGQSIEPIWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLN 861

Query: 189  GEAMLAMIPWYKGFKGDIEPASNTE----YTTKGKWGELEDGKTLRITELPVGRWTREYK 356
             E M  M PWY+GFKG+IE  ++ E    YT  G   E+++  TLRITELPV RWT++Y+
Sbjct: 862  DEQMEPMHPWYRGFKGNIEKTASKEAGVTYTITGVIEEVDEA-TLRITELPVRRWTQDYR 920

Query: 357  QFLKAAQYGKDQTPFIKAYTAHNDKTTVDFTISMSENQMNTAKKEEIWKKFKLTTTLSTA 536
            +FL++   G D  PFIK +  ++D TTV+F + ++E  M  AK+E + KKFKLTTT+ST+
Sbjct: 921  EFLESIITGND--PFIKEFRQYSDDTTVEFEVILTEENMMMAKQEGLLKKFKLTTTISTS 978

Query: 537  NMYLFDKDGAIKKYETPEEILRDFFCLRLDFYKKRMIALTDKLGKAILLLENKVRYINEV 716
            NM+LFD  G IKKY+TPE+IL +FF LR +FY+KR   L D L   +L +ENKVR+I  V
Sbjct: 979  NMHLFDSKGMIKKYDTPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGV 1038

Query: 717  KKGDIDIFNREDDAICADLKANGFKYLPKE---TEPTIAG-------------------- 827
             KG+I + NR+   +  +L+  GF   PK+    E  +AG                    
Sbjct: 1039 VKGEIIVNNRKRADLFLELQTKGFTPFPKKAKTVEVAVAGATDDTEETEENSEVSAKGVQ 1098

Query: 828  REEYDYLLSMTLASFTNKKIIEQFXXXXXXXXXXXXXXXXSTPESLWLRDLEALEQQLEE 1007
              +YDYLLSM + S T +K +++                 +TP+SLWL+DL+ LE QL+E
Sbjct: 1099 ASDYDYLLSMAIGSLTLEK-VQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDE 1157

Query: 1008 K 1010
            +
Sbjct: 1158 Q 1158


>ref|XP_010548805.1| PREDICTED: DNA topoisomerase 2 [Tarenaya hassleriana]
          Length = 1420

 Score =  304 bits (779), Expect = 4e-90
 Identities = 165/364 (45%), Positives = 229/364 (62%), Gaps = 31/364 (8%)
 Frame = +3

Query: 9    DELCLNYLNDDGQSIEPEWFMPIIPMVLVNGIEGTVIGCSSFIPNYNPRAIIANLKRLLH 188
            D++ LNYLN+DGQSIEP W+MPIIP VLVNG EG   G SSFIPNYNPR ++AN++RLL+
Sbjct: 801  DDVLLNYLNEDGQSIEPTWYMPIIPTVLVNGCEGIGTGWSSFIPNYNPREVVANVRRLLN 860

Query: 189  GEAMLAMIPWYKGFKGDIEPASNTE----YTTKGKWGELEDGKTLRITELPVGRWTREYK 356
            GE M+ M PWY+GFKG IE  S  E    YT  G   E++D  TLR+ ELP+ RWT +Y+
Sbjct: 861  GETMVPMDPWYRGFKGTIEKTSTKESGATYTVTGIIEEVDD-TTLRVKELPIRRWTDDYR 919

Query: 357  QFLKAAQYGKDQTPFIKAYTAHNDKTTVDFTISMSENQMNTAKKEEIWKKFKLTTTLSTA 536
            +FL++ +   D  PFI     ++D TTVDF + +SE  M  A++E + KKFKLTTT+ST+
Sbjct: 920  EFLRSMK--TDYGPFILNIREYSDDTTVDFELILSEENMIAAQQEGLVKKFKLTTTISTS 977

Query: 537  NMYLFDKDGAIKKYETPEEILRDFFCLRLDFYKKRMIALTDKLGKAILLLENKVRYINEV 716
            NM+LFD++G IKKYETPE+IL +FF LRL FY+KR   L + L   +L LENKV++I  V
Sbjct: 978  NMHLFDQNGVIKKYETPEQILEEFFDLRLQFYEKRKKILLENLELELLKLENKVKFILGV 1037

Query: 717  KKGDIDIFNREDDAICADLKANGFKYLPKETEP--------------------------- 815
              G+I + NR+   +  +L+  GF   PK+ +P                           
Sbjct: 1038 VSGEIIVSNRKKADLFQELRQKGFTPFPKKAKPVEAAVAGATDTTEESEESSEPAAAPSS 1097

Query: 816  TIAGREEYDYLLSMTLASFTNKKIIEQFXXXXXXXXXXXXXXXXSTPESLWLRDLEALEQ 995
            T     +YDYLLS+ +A+ T +K +++                 +TP+SLWL+DL++LE 
Sbjct: 1098 TFVQGSDYDYLLSLAIATLTLEK-VQELCAERDKMNEEVEDLRKATPKSLWLKDLDSLEV 1156

Query: 996  QLEE 1007
            +L++
Sbjct: 1157 ELDK 1160


>ref|XP_008346962.1| PREDICTED: DNA topoisomerase 2-like [Malus domestica]
          Length = 1435

 Score =  304 bits (779), Expect = 4e-90
 Identities = 165/362 (45%), Positives = 230/362 (63%), Gaps = 29/362 (8%)
 Frame = +3

Query: 9    DELCLNYLNDDGQSIEPEWFMPIIPMVLVNGIEGTVIGCSSFIPNYNPRAIIANLKRLLH 188
            D+  L+YLN+DGQSIEP W++PIIP VLVNG EG   G SS+IPNYNPR I+AN++RLL 
Sbjct: 811  DDRLLDYLNEDGQSIEPTWYVPIIPAVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLD 870

Query: 189  GEAMLAMIPWYKGFKGDIEPA---SNTEYTTKGKWGELEDGKTLRITELPVGRWTREYKQ 359
            G+AM+ M PWY+GF G IE     S   YT  G   E+ +  +LRI+ELP+ RWT++YK+
Sbjct: 871  GDAMVPMDPWYRGFTGTIEKTVKESGVSYTACGIIEEVSE-TSLRISELPIRRWTQDYKE 929

Query: 360  FLKAAQYGKDQT--PFIKAYTAHNDKTTVDFTISMSENQMNTAKKEEIWKKFKLTTTLST 533
            FL++   G D+   PFI+ +T H+D +TVD  + + E ++  AK+E + KKFKLTT++ST
Sbjct: 930  FLESISEGNDKAKDPFIEGFTQHSDHSTVDIIVHLREEKLMAAKQEGLLKKFKLTTSIST 989

Query: 534  ANMYLFDKDGAIKKYETPEEILRDFFCLRLDFYKKRMIALTDKLGKAILLLENKVRYINE 713
            +NM+LFD+ G IKKY+TPE+IL DFF LRL+FY+KR   L + L   +L LENKVR+I  
Sbjct: 990  SNMHLFDRKGVIKKYDTPEQILEDFFHLRLEFYEKRKKVLLEDLELELLKLENKVRFILG 1049

Query: 714  VKKGDIDIFNREDDAICADLKANGFKYLPKET---EPTIAGREE---------------- 836
            V  G+I + NR+   +  +L+  GF   PK+T   EP +AG  E                
Sbjct: 1050 VVNGEIIVSNRKRADLFLELQQKGFTPFPKKTKALEPEVAGATENTEDAEENSEAAIEKG 1109

Query: 837  -----YDYLLSMTLASFTNKKIIEQFXXXXXXXXXXXXXXXXSTPESLWLRDLEALEQQL 1001
                 Y+YL+SM + + T ++ ++                  STP SLWL+DL+ALE +L
Sbjct: 1110 ARISDYEYLISMAIGTLTIER-VQALLADRDKANAEVDGLRKSTPRSLWLKDLDALEMEL 1168

Query: 1002 EE 1007
            +E
Sbjct: 1169 DE 1170