BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Chrysanthemum21_contig00021562
         (1371 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_022005320.1| DNA topoisomerase 2-like [Helianthus annuus]...   588   0.0  
ref|XP_021977342.1| DNA topoisomerase 2-like [Helianthus annuus]...   582   0.0  
ref|XP_023759895.1| DNA topoisomerase 2 [Lactuca sativa]              576   0.0  
gb|PLY88472.1| hypothetical protein LSAT_1X105720 [Lactuca sativa]    575   0.0  
gb|KVI00753.1| Arginine repressor C-terminal-like domain-contain...   518   e-167
ref|XP_020113224.1| DNA topoisomerase 2-like [Ananas comosus]         473   e-160
gb|PON74229.1| DNA topoisomerase II-type [Parasponia andersonii]      495   e-159
ref|XP_008791090.1| PREDICTED: DNA topoisomerase 2-like [Phoenix...   482   e-159
gb|PON46642.1| DNA topoisomerase II-type [Trema orientalis]           493   e-158
ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform ...   495   e-158
ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform ...   495   e-158
ref|XP_015881654.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Z...   492   e-157
ref|XP_015881653.1| PREDICTED: DNA topoisomerase 2 isoform X1 [Z...   492   e-157
ref|XP_009354783.1| PREDICTED: DNA topoisomerase 2-like [Pyrus x...   488   e-156
gb|OAY66581.1| DNA topoisomerase 2 [Ananas comosus]                   488   e-156
emb|CAJ44361.1| putative DNA topoisomerase II [Malus domestica]       488   e-156
gb|KMZ63752.1| DNA topoisomerase 2 [Zostera marina]                   487   e-156
ref|XP_008231458.1| PREDICTED: DNA topoisomerase 2 isoform X2 [P...   487   e-155
ref|XP_008231457.1| PREDICTED: DNA topoisomerase 2 isoform X1 [P...   487   e-155
ref|XP_021824766.1| DNA topoisomerase 2 isoform X2 [Prunus avium]     487   e-155

>ref|XP_022005320.1| DNA topoisomerase 2-like [Helianthus annuus]
 gb|OTF98638.1| putative DNA topoisomerase 2 [Helianthus annuus]
          Length = 1488

 Score =  588 bits (1516), Expect = 0.0
 Identities = 316/491 (64%), Positives = 360/491 (73%), Gaps = 41/491 (8%)
 Frame = +1

Query: 1    DLRRSIPSVVDGLNPGQRKILFCAFKKPIIQEIKVAQFSHYVSEHSAYHHGEASLVGTII 180
            DL+RSIPS+VDGL PGQRKILFCAFKKPI QE+KVAQFS YVSEHSAYHHGE SLV TII
Sbjct: 680  DLQRSIPSMVDGLKPGQRKILFCAFKKPIFQEVKVAQFSGYVSEHSAYHHGEQSLVSTII 739

Query: 181  GMAQNYVGSNNINLLQPIGQFGTRHMGGKEYLNDRCIFTQLSPITRYLFHKADELLLNYL 360
            GMAQN+VGSNNINLL P GQFGTR MGGK++ + R I+T+LSPITR+LFHKADELLLN+L
Sbjct: 740  GMAQNFVGSNNINLLYPSGQFGTRQMGGKDHASGRYIYTRLSPITRHLFHKADELLLNFL 799

Query: 361  NDDGQSIEPARLMPIIPMVLVNGSEG-GLGCSSFISNYNPRDIIANLKRKLRGEAMVPMD 537
            N+DGQSIEP   +PIIPMVLVNGSEG G G SSF+ NYNPRDIIANLKR L GE MVPMD
Sbjct: 800  NEDGQSIEPTWYIPIIPMVLVNGSEGIGTGWSSFVPNYNPRDIIANLKRLLNGEPMVPMD 859

Query: 538  PWYKGFIGKIV-TASKDTGYTTIGKVEELKDGKGLRITELPVGRWTWEYEEFLKAASQYK 714
            PWYK F G I  T SKDTGYTTIG VEE +D   L ITELP+ RWT EY+EFL+AAS   
Sbjct: 860  PWYKWFKGTIQKTTSKDTGYTTIGNVEEKEDENALSITELPIRRWTQEYKEFLEAASLSG 919

Query: 715  KGKAPFIEDYTAHNDKTIVDFTINMSKDQMNTAKQEGFVTKFKLTTTLSTANMCLFDAHG 894
            K K PFIE+Y AHND T V F + M+  QMN AK+EG + KFKLTTTLST+NM LFDA+G
Sbjct: 920  KDKEPFIEEYNAHNDDTTVHFEVIMTASQMNKAKEEGLLKKFKLTTTLSTSNMHLFDANG 979

Query: 895  AIKKYDTPEQILEDFFYLFLAFYEERTIALRGELTKAILLLENKVKFIGEVREGNIRLFN 1074
             IKKYDTPEQILEDFF+L L FYE+R +AL  EL KA L+LENKV+FI EV EG I + N
Sbjct: 980  VIKKYDTPEQILEDFFHLRLDFYEKRKVALLHELGKASLILENKVRFIREVVEGTIVVSN 1039

Query: 1075 REDADICAELKAKGFAYLPKET--KPTTAGAVDHVGRE---------------------- 1182
            R+ AD+CAELK KGF  LPKE   + + AGAVDHV                         
Sbjct: 1040 RKKADLCAELKVKGFTPLPKEAVLEASIAGAVDHVEGSDETEEEEGSGSPADVAAVEEEK 1099

Query: 1183 -------------EYDYLLSMSFAT--FSKFEQLKKEMDAKKQELEMITKSTYESLWVRD 1317
                         EYDYLLSM+  T  + K +QL  E D KK E + +T +  +SLW+RD
Sbjct: 1100 SHVGTASKTIPGTEYDYLLSMAIGTLTYEKMKQLWHERDTKKAEFDELTNTPSKSLWLRD 1159

Query: 1318 LEALDQQLEEQ 1350
            L AL  QL+EQ
Sbjct: 1160 LNALSDQLDEQ 1170


>ref|XP_021977342.1| DNA topoisomerase 2-like [Helianthus annuus]
 gb|OTG37224.1| putative topoisomerase II [Helianthus annuus]
          Length = 1499

 Score =  582 bits (1500), Expect = 0.0
 Identities = 312/489 (63%), Positives = 361/489 (73%), Gaps = 39/489 (7%)
 Frame = +1

Query: 1    DLRRSIPSVVDGLNPGQRKILFCAFKKPIIQEIKVAQFSHYVSEHSAYHHGEASLVGTII 180
            DL+RSIPS+VDGL PGQRKILFCAFKKPI QE+KVAQFS YVSEHSAYHHGE SLV TII
Sbjct: 693  DLQRSIPSMVDGLKPGQRKILFCAFKKPIFQEVKVAQFSGYVSEHSAYHHGEQSLVSTII 752

Query: 181  GMAQNYVGSNNINLLQPIGQFGTRHMGGKEYLNDRCIFTQLSPITRYLFHKADELLLNYL 360
            GMAQN++GSNNINL  P GQFGTR MGGK++ + R I+T+LSPITR+LFHKADELLLNYL
Sbjct: 753  GMAQNFIGSNNINLFYPSGQFGTRQMGGKDHASGRYIYTKLSPITRHLFHKADELLLNYL 812

Query: 361  NDDGQSIEPARLMPIIPMVLVNGSEG-GLGCSSFISNYNPRDIIANLKRKLRGEAMVPMD 537
            N+DGQSIEP   +PIIPMVLVNGSEG G G SSFI NYNPRDIIANLKR L GE MVPMD
Sbjct: 813  NEDGQSIEPTWFIPIIPMVLVNGSEGIGTGWSSFIPNYNPRDIIANLKRLLNGEQMVPMD 872

Query: 538  PWYKGFIGKI-VTASKDTGYTTIGKVEELKDGKGLRITELPVGRWTWEYEEFLKAASQYK 714
            PWYK F G I  T SKDTGYTT+G  EE +D   L ITELP+ RWT EY+EFL+AAS   
Sbjct: 873  PWYKWFKGTIQKTTSKDTGYTTVGVFEENEDNNSLNITELPIRRWTQEYKEFLEAASLSG 932

Query: 715  KGKAPFIEDYTAHNDKTIVDFTINMSKDQMNTAKQEGFVTKFKLTTTLSTANMCLFDAHG 894
            K K PFIE+Y AHND T V F + M+ +QMN AK+EG + KFKLTTTLST+NM LFDA+G
Sbjct: 933  KDKEPFIEEYNAHNDDTTVHFEVVMTANQMNKAKEEGLLKKFKLTTTLSTSNMHLFDANG 992

Query: 895  AIKKYDTPEQILEDFFYLFLAFYEERTIALRGELTKAILLLENKVKFIGEVREGNIRLFN 1074
             IKKYDTPEQILEDFF+L L +YE+R  AL  EL KA L LENKV+FI EV EG + + N
Sbjct: 993  VIKKYDTPEQILEDFFHLRLDYYEKRKNALLHELGKASLQLENKVRFIREVVEGTLVVSN 1052

Query: 1075 REDADICAELKAKGFAYLPKET--KPTTAGAVDHV-GRE--------------------- 1182
            R+ AD+CAELK KG+  LPKE   + + AGAVDHV G E                     
Sbjct: 1053 RKKADLCAELKVKGYTPLPKEAVLEASIAGAVDHVEGSEETEEGSEEETAEMAVEEQKPS 1112

Query: 1183 -----------EYDYLLSMSFA--TFSKFEQLKKEMDAKKQELEMITKSTYESLWVRDLE 1323
                       EYDYLLSM+    T+ K +QL  E D KK E + +T +  +SLW+RDL+
Sbjct: 1113 AGTASKTIPGTEYDYLLSMAIGTLTYEKMQQLWHERDTKKAEFDELTNTPSKSLWLRDLD 1172

Query: 1324 ALDQQLEEQ 1350
            +L+ QL+EQ
Sbjct: 1173 SLNNQLDEQ 1181


>ref|XP_023759895.1| DNA topoisomerase 2 [Lactuca sativa]
          Length = 1508

 Score =  576 bits (1485), Expect = 0.0
 Identities = 313/481 (65%), Positives = 361/481 (75%), Gaps = 31/481 (6%)
 Frame = +1

Query: 1    DLRRSIPSVVDGLNPGQRKILFCAFKKPIIQEIKVAQFSHYVSEHSAYHHGEASLVGTII 180
            DL+RSIPS+VDGL PGQRKILFCAFKKPI QE+KVAQFS YVSEHSAYHHGEASLVGTII
Sbjct: 694  DLQRSIPSMVDGLKPGQRKILFCAFKKPIFQEVKVAQFSGYVSEHSAYHHGEASLVGTII 753

Query: 181  GMAQNYVGSNNINLLQPIGQFGTRHMGGKEYLNDRCIFTQLSPITRYLFHKADELLLNYL 360
            GMAQN+VGSNNINLL P GQFGTR MGGK++ + R I+T+L+PITR+LF+KADELLLNYL
Sbjct: 754  GMAQNFVGSNNINLLYPSGQFGTRQMGGKDHASGRYIYTKLTPITRHLFNKADELLLNYL 813

Query: 361  NDDGQSIEPARLMPIIPMVLVNGSEG-GLGCSSFISNYNPRDIIANLKRKLRGEAMVPMD 537
            ++DGQSIEP   +PIIPMVLVNGSEG G G S+F+ NYNPRDIIANLKR L GE MVPMD
Sbjct: 814  SEDGQSIEPTWYLPIIPMVLVNGSEGIGTGWSTFVPNYNPRDIIANLKRLLNGEEMVPMD 873

Query: 538  PWYKGFIGKI-VTASKDTGYTTIGKVEELKDGKGLRITELPVGRWTWEYEEFLKAASQYK 714
            PWYK F G I  TASKDTGYTT G V+E +D   LRITELPV RWT EY+EFL+ AS   
Sbjct: 874  PWYKWFRGTIQKTASKDTGYTTTGIVDEDEDENTLRITELPVRRWTQEYKEFLEVASTAG 933

Query: 715  KGKAPFIEDYTAHNDKTIVDFTINMSKDQMNTAKQEGFVTKFKLTTTLSTANMCLFDAHG 894
            K K PFIE+Y AHND T V+F I M+ DQMN A+QEG + KFKLTTTLST+NM LFDA+G
Sbjct: 934  KDKEPFIEEYNAHNDDTTVNFQIIMTADQMNKARQEGLLKKFKLTTTLSTSNMHLFDANG 993

Query: 895  AIKKYDTPEQILEDFFYLFLAFYEERTIALRGELTKAILLLENKVKFIGEVREGNIRLFN 1074
             IKKYDTPEQILEDFF L L +YE R  AL  EL K  L LENKV+FI EV EG + + N
Sbjct: 994  VIKKYDTPEQILEDFFPLRLDYYERRKTALLRELGKISLTLENKVRFIKEVVEGTLVVSN 1053

Query: 1075 REDADICAELKAKGFAYLPKET--KPTTAGAVDHV-GRE--------------------- 1182
            R+ AD+ AEL  K +  LPKE   + + AGAVDHV G E                     
Sbjct: 1054 RKKADLYAELAKKKYTPLPKEAVIEASIAGAVDHVEGSEETEEEEASDVPIDVEAAAAXI 1113

Query: 1183 ---EYDYLLSMSFA--TFSKFEQLKKEMDAKKQELEMITKSTYESLWVRDLEALDQQLEE 1347
               EYDYLLSM+ A  T+ K +QL KE D KK E + +T +   SLW++DL+ LD+QL+E
Sbjct: 1114 PGTEYDYLLSMAIASLTYEKMKQLWKERDEKKAEFDELTNTPSRSLWLKDLDDLDKQLDE 1173

Query: 1348 Q 1350
            Q
Sbjct: 1174 Q 1174


>gb|PLY88472.1| hypothetical protein LSAT_1X105720 [Lactuca sativa]
          Length = 1508

 Score =  575 bits (1481), Expect = 0.0
 Identities = 312/481 (64%), Positives = 360/481 (74%), Gaps = 31/481 (6%)
 Frame = +1

Query: 1    DLRRSIPSVVDGLNPGQRKILFCAFKKPIIQEIKVAQFSHYVSEHSAYHHGEASLVGTII 180
            DL+RSIPS+VDGL PGQRKILFCAFKKPI QE+KVAQFS YVSEHSAYHHGEASLVGTII
Sbjct: 694  DLQRSIPSMVDGLKPGQRKILFCAFKKPIFQEVKVAQFSGYVSEHSAYHHGEASLVGTII 753

Query: 181  GMAQNYVGSNNINLLQPIGQFGTRHMGGKEYLNDRCIFTQLSPITRYLFHKADELLLNYL 360
            GMAQN+VGSNNINLL P GQFGTR MGGK++ + R I+T+L+PITR+LF+KADELLLNYL
Sbjct: 754  GMAQNFVGSNNINLLYPSGQFGTRQMGGKDHASGRYIYTKLTPITRHLFNKADELLLNYL 813

Query: 361  NDDGQSIEPARLMPIIPMVLVNGSEG-GLGCSSFISNYNPRDIIANLKRKLRGEAMVPMD 537
            ++DGQSIEP   +PIIPMVLVNGSEG G G S+F+ NYNPRDIIANLKR L GE MVPMD
Sbjct: 814  SEDGQSIEPTWYLPIIPMVLVNGSEGIGTGWSTFVPNYNPRDIIANLKRLLNGEEMVPMD 873

Query: 538  PWYKGFIGKI-VTASKDTGYTTIGKVEELKDGKGLRITELPVGRWTWEYEEFLKAASQYK 714
            PWYK F G I  TASKDTGYTT G V+E +D   LRITELPV RWT EY+EFL+ AS   
Sbjct: 874  PWYKWFRGTIQKTASKDTGYTTTGIVDEDEDENTLRITELPVRRWTQEYKEFLEVASTAG 933

Query: 715  KGKAPFIEDYTAHNDKTIVDFTINMSKDQMNTAKQEGFVTKFKLTTTLSTANMCLFDAHG 894
            K K PFIE+Y AHND T V+F I M+ DQMN A+QEG + KFKLTTTLST+NM LFDA+G
Sbjct: 934  KDKEPFIEEYNAHNDDTTVNFQIIMTADQMNKARQEGLLKKFKLTTTLSTSNMHLFDANG 993

Query: 895  AIKKYDTPEQILEDFFYLFLAFYEERTIALRGELTKAILLLENKVKFIGEVREGNIRLFN 1074
             IKKYDTPEQILEDFF L L +YE R   L  EL K  L LENKV+FI EV EG + + N
Sbjct: 994  VIKKYDTPEQILEDFFPLRLDYYERRKATLLRELGKISLTLENKVRFIKEVVEGTLVVSN 1053

Query: 1075 REDADICAELKAKGFAYLPKET--KPTTAGAVDHV-GRE--------------------- 1182
            R+ AD+ AEL  K +  LPKE   + + AGAVDHV G E                     
Sbjct: 1054 RKKADLYAELAKKKYTPLPKEAVIEASIAGAVDHVEGSEETEEEEASDVPIDVEAAAAXI 1113

Query: 1183 ---EYDYLLSMSFA--TFSKFEQLKKEMDAKKQELEMITKSTYESLWVRDLEALDQQLEE 1347
               EYDYLLSM+ A  T+ K +QL KE D KK E + +T +   SLW++DL+ LD+QL+E
Sbjct: 1114 PGTEYDYLLSMAIASLTYEKMKQLWKERDEKKAEFDELTNTPSRSLWLKDLDDLDKQLDE 1173

Query: 1348 Q 1350
            Q
Sbjct: 1174 Q 1174


>gb|KVI00753.1| Arginine repressor C-terminal-like domain-containing protein [Cynara
            cardunculus var. scolymus]
          Length = 1484

 Score =  518 bits (1334), Expect = e-167
 Identities = 292/488 (59%), Positives = 339/488 (69%), Gaps = 38/488 (7%)
 Frame = +1

Query: 1    DLRRSIPSVVDGLNPGQRKILFCAFKKPIIQEIKVAQFSHYVSEHSAYHHGEASLVGTII 180
            DL+RSIPS+VDGL PGQRKILFCAFKKPI QE+KVAQFS YVSEHSAYHHGE SLV TII
Sbjct: 693  DLQRSIPSMVDGLKPGQRKILFCAFKKPIFQEVKVAQFSGYVSEHSAYHHGEQSLVSTII 752

Query: 181  GMAQNYVGSNNINLLQPIGQFGTRHMGGKEYLNDRCIFTQLSPITRYLFHKADELLLNYL 360
            GMAQNYVGSNNINLL P GQFGTR MGGK++ + R I+T+LSPITR+LF K+DELLL+YL
Sbjct: 753  GMAQNYVGSNNINLLYPSGQFGTRQMGGKDHASGRYIYTKLSPITRHLFQKSDELLLDYL 812

Query: 361  NDDGQSIEPARLMPIIPMVLVNGSEG-GLGCSSFISNYNPRDIIANLKRKLRGEAMVPMD 537
            N+DGQSIEP   MPIIPM LVNGSEG G G S+F+ NYNPRDIIANLKR L  E +VPMD
Sbjct: 813  NEDGQSIEPTWFMPIIPMALVNGSEGIGTGWSTFVPNYNPRDIIANLKRLLNNEPLVPMD 872

Query: 538  PWYKGFIGKIV-TASKDTGYTTIGKVEELKDGKG-LRITELPVGRWTWEYEEFLKAASQY 711
            PWYK F G I+   SKDTGYTT G VEE +D    L I+ELP+ +WT EY+EFL+AAS  
Sbjct: 873  PWYKWFKGTILKMTSKDTGYTTTGIVEEKEDEPNKLIISELPIRKWTQEYKEFLEAASLS 932

Query: 712  KKGKAPFIEDYTAHNDKTIVDFTINMSKDQMNTAKQEGFVTKFKLTTTLSTANMCLFDAH 891
             K K PFIE+Y AHND T V+F + MS +QMN A+QEGF+ KFKLT+ L+T+NM LFDA+
Sbjct: 933  GKDKEPFIEEYMAHNDDTTVNFEVIMSAEQMNNARQEGFLKKFKLTSNLNTSNMHLFDAN 992

Query: 892  GAIKKYDTPEQILEDFFYLFLAFYEERTIALRGELTKAILLLENKVKFIGEVREGNIRLF 1071
            G IKKYDTPEQ                   L  EL KA+L LENKV+FI EV  G I L 
Sbjct: 993  GVIKKYDTPEQ------------------TLLHELRKALLQLENKVRFILEVMAGTIILN 1034

Query: 1072 NREDADICAELKAKGFAYLPKET--KPTTAGAVDHV-GRE-------------------- 1182
            NR   D+ AELK KG+  LPKE   + + AGAVDHV G E                    
Sbjct: 1035 NRVIEDLYAELKDKGYTPLPKEAVLEASIAGAVDHVEGSEETDEATEEETSEVVIEEKYQ 1094

Query: 1183 ----------EYDYLLSMSFATFS--KFEQLKKEMDAKKQELEMITKSTYESLWVRDLEA 1326
                      EYDYLLSM   T +  K  QL  E D KK   + +T +   SLW+RDL+A
Sbjct: 1095 ATASKTIPGTEYDYLLSMELRTLTLKKKNQLCAERDTKKAIFDELTGTPSRSLWLRDLDA 1154

Query: 1327 LDQQLEEQ 1350
            L++QL+EQ
Sbjct: 1155 LEKQLDEQ 1162


>ref|XP_020113224.1| DNA topoisomerase 2-like [Ananas comosus]
          Length = 536

 Score =  473 bits (1216), Expect = e-160
 Identities = 257/466 (55%), Positives = 325/466 (69%), Gaps = 24/466 (5%)
 Frame = +1

Query: 25   VVDGLNPGQRKILFCAFKKPIIQEIKVAQFSHYVSEHSAYHHGEASLVGTIIGMAQNYVG 204
            +VDGL PGQRKILFC+FK+  ++E KVAQFS YVSEHSAYHHGE SL  TIIGMAQ++VG
Sbjct: 1    MVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVG 60

Query: 205  SNNINLLQPIGQFGTRHMGGKEYLNDRCIFTQLSPITRYLFHKADELLLNYLNDDGQSIE 384
            SNNINLLQP GQFGTR+ GGK++ + R I T LSP+TR+LF K D++LL+YLN+DGQSIE
Sbjct: 61   SNNINLLQPNGQFGTRNQGGKDHASARYICTSLSPLTRFLFPKDDDILLDYLNEDGQSIE 120

Query: 385  PARLMPIIPMVLVNGSEG-GLGCSSFISNYNPRDIIANLKRKLRGEAMVPMDPWYKGFIG 561
            P   +PIIPMVL+NGSEG G G SSF+ NYNPRDIIAN++R L  E M PMDPWY+GF G
Sbjct: 121  PTWYIPIIPMVLINGSEGIGTGWSSFVPNYNPRDIIANVRRLLNDEPMQPMDPWYRGFKG 180

Query: 562  KI-VTASKDTG--YTTIGKVEELKDGKGLRITELPVGRWTWEYEEFLKA-ASQYKKGKAP 729
             I  +A+K+ G  YT  G +EE+ D   LRI ELPV RWT +Y+EFL+A  +   K K P
Sbjct: 181  LIEKSATKEAGVTYTITGIIEEV-DNTTLRIMELPVRRWTQDYKEFLEALMTGNDKVKEP 239

Query: 730  FIEDYTAHNDKTIVDFTINMSKDQMNTAKQEGFVTKFKLTTTLSTANMCLFDAHGAIKKY 909
            FI+DY  HND T V F + ++++ +N A QEG   KFKLTTT+ T NM LFD++G IKKY
Sbjct: 240  FIKDYREHNDDTTVHFEVTLTEENLNIALQEGLEKKFKLTTTIGTTNMHLFDSNGVIKKY 299

Query: 910  DTPEQILEDFFYLFLAFYEERTIALRGELTKAILLLENKVKFIGEVREGNIRLFNREDAD 1089
            DTPEQILEDFF+L L FYE+R   L   L   +L L+NKV+FI  V  G I + NR+ A+
Sbjct: 300  DTPEQILEDFFHLRLEFYEKRKKVLLDNLEMDLLKLDNKVRFILGVVRGEIIVNNRKRAE 359

Query: 1090 ICAELKAKGFAYLPKETKPTTAGAVDHVGREE-----------------YDYLLSMSFAT 1218
            +  EL  KGF   PK++K      V     EE                 Y+YLLSM+  T
Sbjct: 360  LFIELHQKGFTPFPKKSKGIDVAIVGATTEEEENEESPEMGKGGVRASDYEYLLSMAIGT 419

Query: 1219 FS--KFEQLKKEMDAKKQELEMITKSTYESLWVRDLEALDQQLEEQ 1350
             +  K ++L  E D  + E+E + K+T  SLW++DL+AL+++LEEQ
Sbjct: 420  LTLEKVQELCGERDKLESEVEELRKATPRSLWLKDLDALERELEEQ 465


>gb|PON74229.1| DNA topoisomerase II-type [Parasponia andersonii]
          Length = 1397

 Score =  495 bits (1274), Expect = e-159
 Identities = 265/474 (55%), Positives = 341/474 (71%), Gaps = 25/474 (5%)
 Frame = +1

Query: 1    DLRRSIPSVVDGLNPGQRKILFCAFKKPIIQEIKVAQFSHYVSEHSAYHHGEASLVGTII 180
            DL+RSIPS+VDGL PGQRKILFC+FK+  ++E KVAQFS YVSEHSAYHHGE SL  TII
Sbjct: 664  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTII 723

Query: 181  GMAQNYVGSNNINLLQPIGQFGTRHMGGKEYLNDRCIFTQLSPITRYLFHKADELLLNYL 360
            GMAQ+Y+GSNNINLL P GQFGTR++GGK++ + R I+T+LSPITR LF K D++LL+Y+
Sbjct: 724  GMAQDYMGSNNINLLMPNGQFGTRNLGGKDHASARYIYTRLSPITRSLFPKDDDILLDYM 783

Query: 361  NDDGQSIEPARLMPIIPMVLVNGSEG-GLGCSSFISNYNPRDIIANLKRKLRGEAMVPMD 537
            ++DGQSIEP   MPIIP VLVNGSEG G G SS+I NYNPRDI+AN++R L G+ MVPMD
Sbjct: 784  DEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGDEMVPMD 843

Query: 538  PWYKGFIGKIVTASKDTG--YTTIGKVEELKDGKGLRITELPVGRWTWEYEEFLKAASQ- 708
            PWY+GF G I  +SK+ G  Y   G +EE+ +   +RITELP+ RWT +Y+EFL++ SQ 
Sbjct: 844  PWYRGFKGTIERSSKEGGASYIVSGIIEEVNE-TTVRITELPIRRWTQDYKEFLESISQG 902

Query: 709  YKKGKAPFIEDYTAHNDKTIVDFTINMSKDQMNTAKQEGFVTKFKLTTTLSTANMCLFDA 888
             +K K PFIE +T H+D + VD  +++ ++ +  AKQEG + KFKLTT++ST NM LFDA
Sbjct: 903  NEKAKDPFIEGFTQHSDHSTVDILVHLPEENLMAAKQEGLLKKFKLTTSISTTNMHLFDA 962

Query: 889  HGAIKKYDTPEQILEDFFYLFLAFYEERTIALRGELTKAILLLENKVKFIGEVREGNIRL 1068
            +G IKKYDTPEQILE+FF+L L FYE+R   L   L   +L LENKV+FI  V +G I +
Sbjct: 963  NGVIKKYDTPEQILEEFFHLRLEFYEKRKKVLLDNLELDLLKLENKVRFILGVVKGEIIV 1022

Query: 1069 FNREDADICAELKAKGFAYLPKETK---PTTAGAVD----------------HVGREEYD 1191
             NR+ AD+  EL+ KGF   PK+TK   P  AGA +                 V   +Y+
Sbjct: 1023 NNRKRADLFVELQKKGFTPFPKKTKSVEPEVAGATEETEDTEDNSNAEAAATEVRISDYE 1082

Query: 1192 YLLSMSFATFS--KFEQLKKEMDAKKQELEMITKSTYESLWVRDLEALDQQLEE 1347
            YLLSM+  T +  K + L  E D    E++ + K+T +SLWVRDL+ALD QL+E
Sbjct: 1083 YLLSMAIGTLTLEKVQALLAERDKLNNEVDELRKATPKSLWVRDLDALDTQLDE 1136


>ref|XP_008791090.1| PREDICTED: DNA topoisomerase 2-like [Phoenix dactylifera]
          Length = 896

 Score =  482 bits (1240), Expect = e-159
 Identities = 263/474 (55%), Positives = 336/474 (70%), Gaps = 24/474 (5%)
 Frame = +1

Query: 1    DLRRSIPSVVDGLNPGQRKILFCAFKKPIIQEIKVAQFSHYVSEHSAYHHGEASLVGTII 180
            DL+RSIPS+VDGL PGQRKILFC+FK+  ++E KVAQFS YVSEHSAYHHGE SL  TII
Sbjct: 124  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTII 183

Query: 181  GMAQNYVGSNNINLLQPIGQFGTRHMGGKEYLNDRCIFTQLSPITRYLFHKADELLLNYL 360
            GMAQ++VGSNNINLLQP GQFGTRH GGK++ + R I+T+LSP+TR+LF K D++LL+YL
Sbjct: 184  GMAQDFVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPLTRFLFPKDDDILLDYL 243

Query: 361  NDDGQSIEPARLMPIIPMVLVNGSEG-GLGCSSFISNYNPRDIIANLKRKLRGEAMVPMD 537
            N+DGQSIEP   MPIIPMVLVNGSEG G G SSF+ NYNPRDI+AN++R L GE M PMD
Sbjct: 244  NEDGQSIEPTWYMPIIPMVLVNGSEGIGTGWSSFVPNYNPRDIVANVRRLLNGEPMQPMD 303

Query: 538  PWYKGFIGKI-VTASKDTGYT-TIGKVEELKDGKGLRITELPVGRWTWEYEEFLKA-ASQ 708
            PWY+GF G I  +ASK+ G T T+  + + +D   LRITELP+ RWT +Y+EFL++  + 
Sbjct: 304  PWYRGFKGLIEKSASKEAGVTYTVTGLSQEEDNTTLRITELPIRRWTQDYKEFLESMMTG 363

Query: 709  YKKGKAPFIEDYTAHNDKTIVDFTINMSKDQMNTAKQEGFVTKFKLTTTLSTANMCLFDA 888
              K K P I+DY   ND   V F I ++++++  A++EG   KFKLTTT+ T NM LFD+
Sbjct: 364  NDKIKEPLIKDYREQNDDVSVHFEIILTEEKLKMAREEGIEKKFKLTTTIGTTNMHLFDS 423

Query: 889  HGAIKKYDTPEQILEDFFYLFLAFYEERTIALRGELTKAILLLENKVKFIGEVREGNIRL 1068
             G IKKYDTPEQILEDFF+L L FY +R  AL   L   +L L+NKV+FI  V  G I +
Sbjct: 424  KGVIKKYDTPEQILEDFFHLRLEFYGKRKKALLDNLELDLLKLDNKVRFILGVVRGEIIV 483

Query: 1069 FNREDADICAELKAKGFAYLPKETK---PTTAGA-VDHVGREE--------------YDY 1194
             NR+ AD+  EL+ KGFA  PK++K      AGA V+  G EE              Y+Y
Sbjct: 484  NNRKRADLFLELQQKGFAPFPKKSKGIDAAIAGATVEEDGNEESPEVVNGGGAKATDYEY 543

Query: 1195 LLSMSFA--TFSKFEQLKKEMDAKKQELEMITKSTYESLWVRDLEALDQQLEEQ 1350
            LLSM+    T+ K ++L  E    + E+E + KS+   LW RDL+A +++L+EQ
Sbjct: 544  LLSMAIGTLTWEKVQELCAERKKLEDEVEELRKSSPRDLWTRDLDAFERELDEQ 597


>gb|PON46642.1| DNA topoisomerase II-type [Trema orientalis]
          Length = 1397

 Score =  493 bits (1270), Expect = e-158
 Identities = 265/474 (55%), Positives = 340/474 (71%), Gaps = 25/474 (5%)
 Frame = +1

Query: 1    DLRRSIPSVVDGLNPGQRKILFCAFKKPIIQEIKVAQFSHYVSEHSAYHHGEASLVGTII 180
            DL+RSIPS+VDGL PGQRKILFC+FK+  ++E KVAQFS YVSEHSAYHHGE SL  TII
Sbjct: 664  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTII 723

Query: 181  GMAQNYVGSNNINLLQPIGQFGTRHMGGKEYLNDRCIFTQLSPITRYLFHKADELLLNYL 360
            GMAQ+Y+GSNNINLL P GQFGTR++GGK++ + R I+T+LSPITR LF K D++LL+YL
Sbjct: 724  GMAQDYMGSNNINLLMPNGQFGTRNLGGKDHASARYIYTRLSPITRSLFPKDDDILLDYL 783

Query: 361  NDDGQSIEPARLMPIIPMVLVNGSEG-GLGCSSFISNYNPRDIIANLKRKLRGEAMVPMD 537
            ++DGQSIEP   MPIIP VLVNGSEG G G SS+I NYNPRDI+AN++R L G+ MVPMD
Sbjct: 784  DEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGDEMVPMD 843

Query: 538  PWYKGFIGKIVTASKDTG--YTTIGKVEELKDGKGLRITELPVGRWTWEYEEFLKAASQ- 708
            PWY+GF G I  +SK+ G  Y   G +EE+ +   +RITELP+ RWT +Y+EFL++ SQ 
Sbjct: 844  PWYRGFKGTIERSSKEGGASYIVSGIIEEVNE-TTVRITELPIRRWTQDYKEFLESISQG 902

Query: 709  YKKGKAPFIEDYTAHNDKTIVDFTINMSKDQMNTAKQEGFVTKFKLTTTLSTANMCLFDA 888
             +K K PFIE +T H+D + VD  +++ ++ +  AKQEG + K KLTT++ST NM LFDA
Sbjct: 903  NEKAKDPFIEGFTQHSDHSTVDILVHLPEENLMAAKQEGLLKKLKLTTSISTTNMHLFDA 962

Query: 889  HGAIKKYDTPEQILEDFFYLFLAFYEERTIALRGELTKAILLLENKVKFIGEVREGNIRL 1068
            +G IKKYDTPEQILE+FF+L L FYE+R   L   L   +L LENKV+FI  V +G I +
Sbjct: 963  NGVIKKYDTPEQILEEFFHLRLEFYEKRKKVLLDNLELDLLKLENKVRFILGVVKGEIIV 1022

Query: 1069 FNREDADICAELKAKGFAYLPKETK---PTTAGAVD----------------HVGREEYD 1191
             NR+ AD+  EL+ KGF   PK+TK   P  AGA +                 V   +Y+
Sbjct: 1023 NNRKRADLFVELQKKGFTPFPKKTKSVEPEVAGATEETEDTEDNSNAEAAATEVRISDYE 1082

Query: 1192 YLLSMSFATFS--KFEQLKKEMDAKKQELEMITKSTYESLWVRDLEALDQQLEE 1347
            YLLSM+  T +  K + L  E D    E++ + K+T +SLWVRDL+ALD QL+E
Sbjct: 1083 YLLSMAIGTLTLEKVQALLAERDKLNNEVDELRKATPKSLWVRDLDALDTQLDE 1136


>ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform X2 [Nelumbo nucifera]
          Length = 1503

 Score =  495 bits (1274), Expect = e-158
 Identities = 270/475 (56%), Positives = 338/475 (71%), Gaps = 25/475 (5%)
 Frame = +1

Query: 1    DLRRSIPSVVDGLNPGQRKILFCAFKKPIIQEIKVAQFSHYVSEHSAYHHGEASLVGTII 180
            DL+RSIPS+VDGL PGQRKILFCAFK+ +I+E KVAQFS YVSEHSAYHHGE SL+ TII
Sbjct: 696  DLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAYHHGEQSLMSTII 755

Query: 181  GMAQNYVGSNNINLLQPIGQFGTRHMGGKEYLNDRCIFTQLSPITRYLFHKADELLLNYL 360
            GMAQ+YVGSNNINL QP GQFGTRH GGK++ + R I+T+LSPITR+LF K D++LL+YL
Sbjct: 756  GMAQDYVGSNNINLFQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKGDDILLDYL 815

Query: 361  NDDGQSIEPARLMPIIPMVLVNGSEG-GLGCSSFISNYNPRDIIANLKRKLRGEAMVPMD 537
            N+DGQSIEP   MPIIP VLVNGSEG G G SS+I NYNPRDI+AN+KR L GE M PMD
Sbjct: 816  NEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIKRLLNGEPMEPMD 875

Query: 538  PWYKGFIGKI-VTASKDTG--YTTIGKVEELKDGKGLRITELPVGRWTWEYEEFLKA-AS 705
            PWYKGF G I  TA+K+ G  YT  G +EE+ +   LRITELP+ RWT +Y+EFL++  +
Sbjct: 876  PWYKGFKGLIEKTATKEAGSSYTVSGIIEEINE-TTLRITELPIRRWTQDYKEFLESIMT 934

Query: 706  QYKKGKAPFIEDYTAHNDKTIVDFTINMSKDQMNTAKQEGFVTKFKLTTTLSTANMCLFD 885
               K K PFI+DY  HND T V F I +S++ +  AKQEG + KFKLTTT+ST+NM LFD
Sbjct: 935  GNDKIKEPFIKDYKEHNDDTTVHFEIILSEENLMMAKQEGLMKKFKLTTTISTSNMHLFD 994

Query: 886  AHGAIKKYDTPEQILEDFFYLFLAFYEERTIALRGELTKAILLLENKVKFIGEVREGNIR 1065
              G IKKYD PEQILE+FF+L L FYE+R       L   +L L+NKV+FI  V +G I 
Sbjct: 995  PKGTIKKYDNPEQILEEFFHLRLEFYEKRKKTQLDNLELDLLKLDNKVRFILGVVKGEII 1054

Query: 1066 LFNREDADICAELKAKGFAYLPKETK---PTTAGAVDH---------------VGREEYD 1191
            + NR+  D+  EL+ KGF   PK+TK      AGA +                V   +Y+
Sbjct: 1055 VSNRKRVDLFLELQQKGFTPFPKKTKALEAAVAGANEDGEENEENSEVVSSRGVRASDYE 1114

Query: 1192 YLLSMSFATFS--KFEQLKKEMDAKKQELEMITKSTYESLWVRDLEALDQQLEEQ 1350
            YLLSM+  T +  K ++L  + D    E+E + K+T  SLW+ DL+AL+++L+EQ
Sbjct: 1115 YLLSMAIGTLTLEKVQELCSDRDKLNHEVEELRKATPNSLWMNDLDALEKELDEQ 1169


>ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform X1 [Nelumbo nucifera]
          Length = 1504

 Score =  495 bits (1274), Expect = e-158
 Identities = 270/475 (56%), Positives = 338/475 (71%), Gaps = 25/475 (5%)
 Frame = +1

Query: 1    DLRRSIPSVVDGLNPGQRKILFCAFKKPIIQEIKVAQFSHYVSEHSAYHHGEASLVGTII 180
            DL+RSIPS+VDGL PGQRKILFCAFK+ +I+E KVAQFS YVSEHSAYHHGE SL+ TII
Sbjct: 696  DLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAYHHGEQSLMSTII 755

Query: 181  GMAQNYVGSNNINLLQPIGQFGTRHMGGKEYLNDRCIFTQLSPITRYLFHKADELLLNYL 360
            GMAQ+YVGSNNINL QP GQFGTRH GGK++ + R I+T+LSPITR+LF K D++LL+YL
Sbjct: 756  GMAQDYVGSNNINLFQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKGDDILLDYL 815

Query: 361  NDDGQSIEPARLMPIIPMVLVNGSEG-GLGCSSFISNYNPRDIIANLKRKLRGEAMVPMD 537
            N+DGQSIEP   MPIIP VLVNGSEG G G SS+I NYNPRDI+AN+KR L GE M PMD
Sbjct: 816  NEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIKRLLNGEPMEPMD 875

Query: 538  PWYKGFIGKI-VTASKDTG--YTTIGKVEELKDGKGLRITELPVGRWTWEYEEFLKA-AS 705
            PWYKGF G I  TA+K+ G  YT  G +EE+ +   LRITELP+ RWT +Y+EFL++  +
Sbjct: 876  PWYKGFKGLIEKTATKEAGSSYTVSGIIEEINE-TTLRITELPIRRWTQDYKEFLESIMT 934

Query: 706  QYKKGKAPFIEDYTAHNDKTIVDFTINMSKDQMNTAKQEGFVTKFKLTTTLSTANMCLFD 885
               K K PFI+DY  HND T V F I +S++ +  AKQEG + KFKLTTT+ST+NM LFD
Sbjct: 935  GNDKIKEPFIKDYKEHNDDTTVHFEIILSEENLMMAKQEGLMKKFKLTTTISTSNMHLFD 994

Query: 886  AHGAIKKYDTPEQILEDFFYLFLAFYEERTIALRGELTKAILLLENKVKFIGEVREGNIR 1065
              G IKKYD PEQILE+FF+L L FYE+R       L   +L L+NKV+FI  V +G I 
Sbjct: 995  PKGTIKKYDNPEQILEEFFHLRLEFYEKRKKTQLDNLELDLLKLDNKVRFILGVVKGEII 1054

Query: 1066 LFNREDADICAELKAKGFAYLPKETK---PTTAGAVDH---------------VGREEYD 1191
            + NR+  D+  EL+ KGF   PK+TK      AGA +                V   +Y+
Sbjct: 1055 VSNRKRVDLFLELQQKGFTPFPKKTKALEAAVAGANEDGEENEENSEVVSSRGVRASDYE 1114

Query: 1192 YLLSMSFATFS--KFEQLKKEMDAKKQELEMITKSTYESLWVRDLEALDQQLEEQ 1350
            YLLSM+  T +  K ++L  + D    E+E + K+T  SLW+ DL+AL+++L+EQ
Sbjct: 1115 YLLSMAIGTLTLEKVQELCSDRDKLNHEVEELRKATPNSLWMNDLDALEKELDEQ 1169


>ref|XP_015881654.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Ziziphus jujuba]
          Length = 1486

 Score =  492 bits (1266), Expect = e-157
 Identities = 265/470 (56%), Positives = 335/470 (71%), Gaps = 21/470 (4%)
 Frame = +1

Query: 1    DLRRSIPSVVDGLNPGQRKILFCAFKKPIIQEIKVAQFSHYVSEHSAYHHGEASLVGTII 180
            DL+RSIPS+VDGL PGQRKILFC+FK+   +E KVAQFS YVSEHSAYHHGE SL  TII
Sbjct: 702  DLQRSIPSMVDGLKPGQRKILFCSFKRNFFKEAKVAQFSGYVSEHSAYHHGEQSLASTII 761

Query: 181  GMAQNYVGSNNINLLQPIGQFGTRHMGGKEYLNDRCIFTQLSPITRYLFHKADELLLNYL 360
            GMAQ+YVGSNNINLLQP GQFGTR++GGK++ + R IFT+LSPITR+LF K D+ LL+YL
Sbjct: 762  GMAQDYVGSNNINLLQPNGQFGTRNLGGKDHASARYIFTRLSPITRFLFPKDDDKLLDYL 821

Query: 361  NDDGQSIEPARLMPIIPMVLVNGSEG-GLGCSSFISNYNPRDIIANLKRKLRGEAMVPMD 537
            N+DGQ+IEP   +PIIP VLVNGSEG G G SS+I NYNPRDI+AN++R L G +MVPMD
Sbjct: 822  NEDGQTIEPTWYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRRLLNGHSMVPMD 881

Query: 538  PWYKGFIGKIVTASKDTG--YTTIGKVEELKDGKGLRITELPVGRWTWEYEEFLKAASQ- 708
            PWY+GF G I    K+ G  YT  G +EE+ +   +RITELP+ +WT +Y+EFL++ SQ 
Sbjct: 882  PWYRGFKGTIEKTVKEAGVSYTISGILEEVNE-TTIRITELPIRKWTQDYKEFLESISQG 940

Query: 709  YKKGKAPFIEDYTAHNDKTIVDFTINMSKDQMNTAKQEGFVTKFKLTTTLSTANMCLFDA 888
              K K PFIE +T H+D   VD  ++M ++ +  AKQEG + KFKLTTT+ST+NM LFDA
Sbjct: 941  NDKAKDPFIEGFTQHSDHITVDILVHMPEENLVAAKQEGLLKKFKLTTTISTSNMHLFDA 1000

Query: 889  HGAIKKYDTPEQILEDFFYLFLAFYEERTIALRGELTKAILLLENKVKFIGEVREGNIRL 1068
             G IKKYDTPEQILE+FF+L L FYE+R   L   L   +L LENKV+FI  V    I +
Sbjct: 1001 KGVIKKYDTPEQILEEFFHLRLEFYEKRKQVLLDNLEMELLKLENKVRFILGVVNEEIIV 1060

Query: 1069 FNREDADICAELKAKGFAYLPKETK---PTTAGAVDHVGREE------------YDYLLS 1203
             NR+ AD+  EL+ KGF   PK+ K   P  AGA D+    E            Y+YLLS
Sbjct: 1061 SNRKRADLFLELQQKGFTPFPKKAKSVEPEVAGATDYTEETEDNSNPDGVRISDYEYLLS 1120

Query: 1204 MSFATFS--KFEQLKKEMDAKKQELEMITKSTYESLWVRDLEALDQQLEE 1347
            M+  T +  K + L  E D    E++ + K+T +SLW +DL+ALD++L+E
Sbjct: 1121 MAIGTLTLEKVQALCAERDKLNGEVDDLRKATPKSLWEKDLDALDKELDE 1170


>ref|XP_015881653.1| PREDICTED: DNA topoisomerase 2 isoform X1 [Ziziphus jujuba]
          Length = 1487

 Score =  492 bits (1266), Expect = e-157
 Identities = 265/470 (56%), Positives = 335/470 (71%), Gaps = 21/470 (4%)
 Frame = +1

Query: 1    DLRRSIPSVVDGLNPGQRKILFCAFKKPIIQEIKVAQFSHYVSEHSAYHHGEASLVGTII 180
            DL+RSIPS+VDGL PGQRKILFC+FK+   +E KVAQFS YVSEHSAYHHGE SL  TII
Sbjct: 702  DLQRSIPSMVDGLKPGQRKILFCSFKRNFFKEAKVAQFSGYVSEHSAYHHGEQSLASTII 761

Query: 181  GMAQNYVGSNNINLLQPIGQFGTRHMGGKEYLNDRCIFTQLSPITRYLFHKADELLLNYL 360
            GMAQ+YVGSNNINLLQP GQFGTR++GGK++ + R IFT+LSPITR+LF K D+ LL+YL
Sbjct: 762  GMAQDYVGSNNINLLQPNGQFGTRNLGGKDHASARYIFTRLSPITRFLFPKDDDKLLDYL 821

Query: 361  NDDGQSIEPARLMPIIPMVLVNGSEG-GLGCSSFISNYNPRDIIANLKRKLRGEAMVPMD 537
            N+DGQ+IEP   +PIIP VLVNGSEG G G SS+I NYNPRDI+AN++R L G +MVPMD
Sbjct: 822  NEDGQTIEPTWYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRRLLNGHSMVPMD 881

Query: 538  PWYKGFIGKIVTASKDTG--YTTIGKVEELKDGKGLRITELPVGRWTWEYEEFLKAASQ- 708
            PWY+GF G I    K+ G  YT  G +EE+ +   +RITELP+ +WT +Y+EFL++ SQ 
Sbjct: 882  PWYRGFKGTIEKTVKEAGVSYTISGILEEVNE-TTIRITELPIRKWTQDYKEFLESISQG 940

Query: 709  YKKGKAPFIEDYTAHNDKTIVDFTINMSKDQMNTAKQEGFVTKFKLTTTLSTANMCLFDA 888
              K K PFIE +T H+D   VD  ++M ++ +  AKQEG + KFKLTTT+ST+NM LFDA
Sbjct: 941  NDKAKDPFIEGFTQHSDHITVDILVHMPEENLVAAKQEGLLKKFKLTTTISTSNMHLFDA 1000

Query: 889  HGAIKKYDTPEQILEDFFYLFLAFYEERTIALRGELTKAILLLENKVKFIGEVREGNIRL 1068
             G IKKYDTPEQILE+FF+L L FYE+R   L   L   +L LENKV+FI  V    I +
Sbjct: 1001 KGVIKKYDTPEQILEEFFHLRLEFYEKRKQVLLDNLEMELLKLENKVRFILGVVNEEIIV 1060

Query: 1069 FNREDADICAELKAKGFAYLPKETK---PTTAGAVDHVGREE------------YDYLLS 1203
             NR+ AD+  EL+ KGF   PK+ K   P  AGA D+    E            Y+YLLS
Sbjct: 1061 SNRKRADLFLELQQKGFTPFPKKAKSVEPEVAGATDYTEETEDNSNPDGVRISDYEYLLS 1120

Query: 1204 MSFATFS--KFEQLKKEMDAKKQELEMITKSTYESLWVRDLEALDQQLEE 1347
            M+  T +  K + L  E D    E++ + K+T +SLW +DL+ALD++L+E
Sbjct: 1121 MAIGTLTLEKVQALCAERDKLNGEVDDLRKATPKSLWEKDLDALDKELDE 1170


>ref|XP_009354783.1| PREDICTED: DNA topoisomerase 2-like [Pyrus x bretschneideri]
 ref|XP_009354789.1| PREDICTED: DNA topoisomerase 2-like [Pyrus x bretschneideri]
          Length = 1467

 Score =  488 bits (1256), Expect = e-156
 Identities = 261/473 (55%), Positives = 338/473 (71%), Gaps = 24/473 (5%)
 Frame = +1

Query: 1    DLRRSIPSVVDGLNPGQRKILFCAFKKPIIQEIKVAQFSHYVSEHSAYHHGEASLVGTII 180
            DL+RSIPS+VDGL PGQRKILF +FK+  ++E KVAQFS YVSEHSAYHHGE SL  TII
Sbjct: 699  DLQRSIPSMVDGLKPGQRKILFSSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTII 758

Query: 181  GMAQNYVGSNNINLLQPIGQFGTRHMGGKEYLNDRCIFTQLSPITRYLFHKADELLLNYL 360
            GMAQ++VGSNNINLLQP GQFGTR++GGK++ + R I+T+LS ITR+LF K D+ LL+YL
Sbjct: 759  GMAQDFVGSNNINLLQPNGQFGTRNLGGKDHASARYIYTRLSHITRFLFSKDDDRLLDYL 818

Query: 361  NDDGQSIEPARLMPIIPMVLVNGSEG-GLGCSSFISNYNPRDIIANLKRKLRGEAMVPMD 537
            N+DGQSIEP   +PIIP VLVNGSEG G G SS+I NYNPRDI+AN++R L G+AMVPMD
Sbjct: 819  NEDGQSIEPTWYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLDGDAMVPMD 878

Query: 538  PWYKGFIGKIVTASKDTG--YTTIGKVEELKDGKGLRITELPVGRWTWEYEEFLKAASQ- 708
            PWY+GF G I    KD+G  YT  G +EE+ +   LRI+ELP+ RWT +Y+EFL++ S+ 
Sbjct: 879  PWYRGFTGTIEKNVKDSGVSYTACGIIEEVSE-TSLRISELPIRRWTQDYKEFLESISEG 937

Query: 709  YKKGKAPFIEDYTAHNDKTIVDFTINMSKDQMNTAKQEGFVTKFKLTTTLSTANMCLFDA 888
              K K PFIE +T H+D + VD  +++ ++++  AKQEG + KFKLTT++ST+NM LFD 
Sbjct: 938  NDKAKDPFIEGFTQHSDHSTVDIIVHLREEKLMAAKQEGLLKKFKLTTSISTSNMHLFDR 997

Query: 889  HGAIKKYDTPEQILEDFFYLFLAFYEERTIALRGELTKAILLLENKVKFIGEVREGNIRL 1068
             G IKKYDTPEQILEDFF+L L FYEER   L   L   +L LENKV+FI  V  G I +
Sbjct: 998  KGVIKKYDTPEQILEDFFHLRLEFYEERKKVLLENLELELLKLENKVRFILGVVNGEIIV 1057

Query: 1069 FNREDADICAELKAKGFAYLPKETK---PTTAGAVDHVGREE---------------YDY 1194
             NR+ AD+  EL+ KGF   PK+TK   P  AGA ++    E               Y+Y
Sbjct: 1058 SNRKRADLFLELQEKGFTPFPKKTKVLEPEVAGATENTEDAEENSEAAIEKGARISDYEY 1117

Query: 1195 LLSMSFATFS--KFEQLKKEMDAKKQELEMITKSTYESLWVRDLEALDQQLEE 1347
            L+SM+  T +  + + L  + D    E++ + KST  SLW++DL+AL+ +L+E
Sbjct: 1118 LISMAIGTLTIERVQALLADRDKANSEVDELKKSTPRSLWLKDLDALEMELDE 1170


>gb|OAY66581.1| DNA topoisomerase 2 [Ananas comosus]
          Length = 1476

 Score =  488 bits (1256), Expect = e-156
 Identities = 264/474 (55%), Positives = 334/474 (70%), Gaps = 24/474 (5%)
 Frame = +1

Query: 1    DLRRSIPSVVDGLNPGQRKILFCAFKKPIIQEIKVAQFSHYVSEHSAYHHGEASLVGTII 180
            DL+RSIPS+VDGL PGQRKILFC+FK+  ++E KVAQFS YVSEHSAYHHGE SL  TII
Sbjct: 698  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTII 757

Query: 181  GMAQNYVGSNNINLLQPIGQFGTRHMGGKEYLNDRCIFTQLSPITRYLFHKADELLLNYL 360
            GMAQ++VGSNNINLLQP GQFGTR+ GGK++ + R I+T LSP+TR+LF K D++LL+YL
Sbjct: 758  GMAQDFVGSNNINLLQPNGQFGTRNQGGKDHASARYIYTSLSPLTRFLFPKDDDILLDYL 817

Query: 361  NDDGQSIEPARLMPIIPMVLVNGSEG-GLGCSSFISNYNPRDIIANLKRKLRGEAMVPMD 537
            N+DGQSIEP   +PIIPMVL+NGSEG G G SSF+ NYNPRDIIAN++R L  E M PMD
Sbjct: 818  NEDGQSIEPTWYIPIIPMVLINGSEGIGTGWSSFVPNYNPRDIIANVRRLLNDEPMQPMD 877

Query: 538  PWYKGFIGKI-VTASKDTG--YTTIGKVEELKDGKGLRITELPVGRWTWEYEEFLKA-AS 705
            PWY+GF G I  +A+K+ G  YT  G +EE+ D   LRI ELPV RWT +Y+EFL+A  +
Sbjct: 878  PWYRGFKGLIEKSATKEAGVTYTITGIIEEV-DNATLRIMELPVRRWTQDYKEFLEALMT 936

Query: 706  QYKKGKAPFIEDYTAHNDKTIVDFTINMSKDQMNTAKQEGFVTKFKLTTTLSTANMCLFD 885
               K K PFI+DY  HND T V F + ++++ +N A QEG   KFKLTTT+ T NM LFD
Sbjct: 937  GNDKVKEPFIKDYREHNDDTTVHFEVTLTEENLNIALQEGLEKKFKLTTTIGTTNMHLFD 996

Query: 886  AHGAIKKYDTPEQILEDFFYLFLAFYEERTIALRGELTKAILLLENKVKFIGEVREGNIR 1065
            ++G IKKYDTPEQILEDFF+L L FYE+R   L   L   +L L+NKV+FI  V  G I 
Sbjct: 997  SNGVIKKYDTPEQILEDFFHLRLEFYEKRKKVLLDNLEMDLLKLDNKVRFILGVVRGEII 1056

Query: 1066 LFNREDADICAELKAKGFAYLPKETKPTTAGAVDHVGREE-----------------YDY 1194
            + NR+ A++  EL  KGF   PK++K      V     EE                 Y+Y
Sbjct: 1057 VNNRKRAELFIELHQKGFTPFPKKSKGIDVAIVGATTEEEENEESPEMGKGGVRASDYEY 1116

Query: 1195 LLSMSFATFS--KFEQLKKEMDAKKQELEMITKSTYESLWVRDLEALDQQLEEQ 1350
            LLSM+  T +  K ++L  E D  + E+E + K+T  SLW++DL+AL+++LEEQ
Sbjct: 1117 LLSMAIGTLTLEKVQELCGERDKLESEVEELRKATPRSLWLKDLDALERELEEQ 1170


>emb|CAJ44361.1| putative DNA topoisomerase II [Malus domestica]
          Length = 1467

 Score =  488 bits (1255), Expect = e-156
 Identities = 259/472 (54%), Positives = 339/472 (71%), Gaps = 24/472 (5%)
 Frame = +1

Query: 1    DLRRSIPSVVDGLNPGQRKILFCAFKKPIIQEIKVAQFSHYVSEHSAYHHGEASLVGTII 180
            DL+RSIPS+VDGL PGQRKILF +FK+  ++E KVAQFS YVSEHSAYHHGE SL  TII
Sbjct: 660  DLQRSIPSMVDGLKPGQRKILFSSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTII 719

Query: 181  GMAQNYVGSNNINLLQPIGQFGTRHMGGKEYLNDRCIFTQLSPITRYLFHKADELLLNYL 360
            GMAQ++VGSNNINLLQP GQFGTR++GGK++ + R I+T+LSPITR+LF K D+ LL+YL
Sbjct: 720  GMAQDFVGSNNINLLQPNGQFGTRNLGGKDHASARYIYTRLSPITRFLFSKDDDRLLDYL 779

Query: 361  NDDGQSIEPARLMPIIPMVLVNGSEG-GLGCSSFISNYNPRDIIANLKRKLRGEAMVPMD 537
            N+DGQSIEP   +PIIP VLVNGSEG G G SS+I NYNPRDI+AN++R L G+AMVPMD
Sbjct: 780  NEDGQSIEPTWYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLDGDAMVPMD 839

Query: 538  PWYKGFIGKIVTASKDTG--YTTIGKVEELKDGKGLRITELPVGRWTWEYEEFLKAASQ- 708
            PWY+GF G I    K++G  YT  G +EE+ +   LRI+ELP+ RWT +Y+EFL++ S+ 
Sbjct: 840  PWYRGFTGTIEKTVKESGVSYTACGIIEEVSE-TSLRISELPIRRWTQDYKEFLESISEG 898

Query: 709  YKKGKAPFIEDYTAHNDKTIVDFTINMSKDQMNTAKQEGFVTKFKLTTTLSTANMCLFDA 888
              K K PFIE +T H+D + VD  +++ ++++  AKQEG + KFKLTT++ST+NM LFD 
Sbjct: 899  NDKAKDPFIEGFTQHSDHSTVDIIVHLREEKLMAAKQEGLLKKFKLTTSISTSNMHLFDR 958

Query: 889  HGAIKKYDTPEQILEDFFYLFLAFYEERTIALRGELTKAILLLENKVKFIGEVREGNIRL 1068
             G IKKYDTPEQILEDFF+L L FYE+R   L  +L   +L LENKV+FI  V  G I +
Sbjct: 959  KGVIKKYDTPEQILEDFFHLRLEFYEKRKKVLLEDLELELLKLENKVRFILGVVNGEIIV 1018

Query: 1069 FNREDADICAELKAKGFAYLPKETK---PTTAGAVDHVGREE---------------YDY 1194
             NR+ AD+  EL+ KGF   PK+TK   P  AGA ++    E               Y+Y
Sbjct: 1019 SNRKRADLFLELQQKGFTPFPKKTKALEPEVAGATENTEDAEENSEAAIEKGARISDYEY 1078

Query: 1195 LLSMSFATFS--KFEQLKKEMDAKKQELEMITKSTYESLWVRDLEALDQQLE 1344
            L+SM+  T +  + + L  + D    E++ + KST  SLW++DL+AL+ +L+
Sbjct: 1079 LISMAIGTLTIERVQALLADRDKANAEVDELRKSTPRSLWLKDLDALEMELD 1130


>gb|KMZ63752.1| DNA topoisomerase 2 [Zostera marina]
          Length = 1454

 Score =  487 bits (1254), Expect = e-156
 Identities = 263/470 (55%), Positives = 336/470 (71%), Gaps = 24/470 (5%)
 Frame = +1

Query: 1    DLRRSIPSVVDGLNPGQRKILFCAFKKPIIQEIKVAQFSHYVSEHSAYHHGEASLVGTII 180
            DL+RSIPS+VDGL PGQRKILFC FK+   +E KVAQFS YVSEHSAYHHGE SL GTII
Sbjct: 695  DLQRSIPSMVDGLKPGQRKILFCCFKRNFTKEAKVAQFSGYVSEHSAYHHGETSLAGTII 754

Query: 181  GMAQNYVGSNNINLLQPIGQFGTRHMGGKEYLNDRCIFTQLSPITRYLFHKADELLLNYL 360
            GMAQ++VGSNNINLLQP GQFGTR+ GGK++ + R I+TQLSP+TR+LF K D++LL+YL
Sbjct: 755  GMAQDFVGSNNINLLQPNGQFGTRNQGGKDHASARYIYTQLSPLTRFLFPKDDDILLDYL 814

Query: 361  NDDGQSIEPARLMPIIPMVLVNGSEG-GLGCSSFISNYNPRDIIANLKRKLRGEAMVPMD 537
            N+DGQSIEP   MPI+P +LVNGSEG G G S++I NYNPRDI+ANL+R L  E MVPMD
Sbjct: 815  NEDGQSIEPTWYMPILPTILVNGSEGIGTGWSTYIPNYNPRDIVANLRRLLNDEPMVPMD 874

Query: 538  PWYKGFIGKI-VTASKDTG--YTTIGKVEELKDGKGLRITELPVGRWTWEYEEFLKA-AS 705
            PWY+GF G I  +A+K+TG  YTT G +EE+ D   +R+TELP+ RWT EY+EFL+A  +
Sbjct: 875  PWYRGFKGLIDKSATKETGVTYTTTGTLEEVNDTM-IRVTELPIRRWTQEYKEFLEAQMT 933

Query: 706  QYKKGKAPFIEDYTAHNDKTIVDFTINMSKDQMNTAKQEGFVTKFKLTTTLSTANMCLFD 885
              +K K PF+ DY  HND T V+F + +S++  + A+QEG + K KLTT++ST+NM LFD
Sbjct: 934  GNEKIKEPFVMDYREHNDDTSVNFEVFLSEENFSIARQEGLLKKLKLTTSISTSNMHLFD 993

Query: 886  AHGAIKKYDTPEQILEDFFYLFLAFYEERTIALRGELTKAILLLENKVKFIGEVREGNIR 1065
            A+GAIKKYD PEQILE+FF++ LAFYE+R   L   L   +L L NKV+FI  V EG I 
Sbjct: 994  ANGAIKKYDNPEQILEEFFHMRLAFYEKRKKVLLDNLELELLKLSNKVRFILGVVEGKIV 1053

Query: 1066 LFNREDADICAELKAKGFAYLPKETK-------PTTAGAVDH----------VGREEYDY 1194
            + NR+++++C EL   GF+  PK+ K         T  A D+          V   +YDY
Sbjct: 1054 VNNRKNSELCIELYHMGFSVFPKKKKGIEIVVAENTEEAEDNEDGDEFGTSGVKASDYDY 1113

Query: 1195 LLSMSFATFS--KFEQLKKEMDAKKQELEMITKSTYESLWVRDLEALDQQ 1338
            LLSMS  T +  K EQL  E      E+E +  ST  SLW++DL+A + +
Sbjct: 1114 LLSMSIKTLTREKVEQLCAEKKNLDNEVEELRGSTGSSLWIKDLDAFENE 1163


>ref|XP_008231458.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Prunus mume]
          Length = 1470

 Score =  487 bits (1254), Expect = e-155
 Identities = 260/473 (54%), Positives = 334/473 (70%), Gaps = 24/473 (5%)
 Frame = +1

Query: 1    DLRRSIPSVVDGLNPGQRKILFCAFKKPIIQEIKVAQFSHYVSEHSAYHHGEASLVGTII 180
            DL+RSIPS+VDGL PGQRKILFC+FK+  ++E KVAQFS YVSEHSAYHHGE SL  TII
Sbjct: 696  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTII 755

Query: 181  GMAQNYVGSNNINLLQPIGQFGTRHMGGKEYLNDRCIFTQLSPITRYLFHKADELLLNYL 360
            GMAQ+YVGSNNINLLQP GQFGTR++GGK++ + R I+T+LSPITR+LF K D+ LL+YL
Sbjct: 756  GMAQDYVGSNNINLLQPNGQFGTRNLGGKDHASARYIYTRLSPITRFLFPKDDDRLLDYL 815

Query: 361  NDDGQSIEPARLMPIIPMVLVNGSEG-GLGCSSFISNYNPRDIIANLKRKLRGEAMVPMD 537
            N+DGQSIEP   +PIIP VLVNGSEG G G SS+I NYNPRDI+AN++R L GEAMVPMD
Sbjct: 816  NEDGQSIEPTWYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEAMVPMD 875

Query: 538  PWYKGFIGKIVTASKDTG--YTTIGKVEELKDGKGLRITELPVGRWTWEYEEFLKAASQ- 708
            PWY+GF G I    K++G  YT  G +EE  +   +RI+ELP+ RWT +Y+EFL++ SQ 
Sbjct: 876  PWYRGFAGTIEKTVKESGVSYTVCGVIEEGNE-TTVRISELPIRRWTQDYKEFLESISQG 934

Query: 709  YKKGKAPFIEDYTAHNDKTIVDFTINMSKDQMNTAKQEGFVTKFKLTTTLSTANMCLFDA 888
              K K PFIE +T H+D + VD  +++ ++ +  A+QEG + KFKLTT++ST+NM LFD 
Sbjct: 935  NDKAKDPFIEGFTQHSDHSTVDIIVHLPEENLMAARQEGLLKKFKLTTSISTSNMHLFDP 994

Query: 889  HGAIKKYDTPEQILEDFFYLFLAFYEERTIALRGELTKAILLLENKVKFIGEVREGNIRL 1068
             G IKKYDTPEQILE+FF+L L FYE+R   L   L   +L LENKV+FI  V  G I +
Sbjct: 995  KGVIKKYDTPEQILEEFFHLRLEFYEKRKKVLLDNLEMELLKLENKVRFILAVVNGEIIV 1054

Query: 1069 FNREDADICAELKAKGFAYLPKETK---PTTAGAVDHVGREE---------------YDY 1194
             NR  AD+  EL+ KGF   PK+TK   P  AGA++     E               Y+Y
Sbjct: 1055 SNRRRADLFLELQQKGFTPFPKKTKAQEPEVAGAIEDTEETEENSESASGNGARISDYEY 1114

Query: 1195 LLSMSFATFS--KFEQLKKEMDAKKQELEMITKSTYESLWVRDLEALDQQLEE 1347
            L+SM+  T +  + + L  + D    E+  +  ST  SLW++DL+AL+ +L E
Sbjct: 1115 LISMAIGTLTIERVQALCADRDKVNNEVAELRNSTPRSLWLKDLDALEMELGE 1167


>ref|XP_008231457.1| PREDICTED: DNA topoisomerase 2 isoform X1 [Prunus mume]
          Length = 1471

 Score =  487 bits (1254), Expect = e-155
 Identities = 260/473 (54%), Positives = 334/473 (70%), Gaps = 24/473 (5%)
 Frame = +1

Query: 1    DLRRSIPSVVDGLNPGQRKILFCAFKKPIIQEIKVAQFSHYVSEHSAYHHGEASLVGTII 180
            DL+RSIPS+VDGL PGQRKILFC+FK+  ++E KVAQFS YVSEHSAYHHGE SL  TII
Sbjct: 696  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTII 755

Query: 181  GMAQNYVGSNNINLLQPIGQFGTRHMGGKEYLNDRCIFTQLSPITRYLFHKADELLLNYL 360
            GMAQ+YVGSNNINLLQP GQFGTR++GGK++ + R I+T+LSPITR+LF K D+ LL+YL
Sbjct: 756  GMAQDYVGSNNINLLQPNGQFGTRNLGGKDHASARYIYTRLSPITRFLFPKDDDRLLDYL 815

Query: 361  NDDGQSIEPARLMPIIPMVLVNGSEG-GLGCSSFISNYNPRDIIANLKRKLRGEAMVPMD 537
            N+DGQSIEP   +PIIP VLVNGSEG G G SS+I NYNPRDI+AN++R L GEAMVPMD
Sbjct: 816  NEDGQSIEPTWYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEAMVPMD 875

Query: 538  PWYKGFIGKIVTASKDTG--YTTIGKVEELKDGKGLRITELPVGRWTWEYEEFLKAASQ- 708
            PWY+GF G I    K++G  YT  G +EE  +   +RI+ELP+ RWT +Y+EFL++ SQ 
Sbjct: 876  PWYRGFAGTIEKTVKESGVSYTVCGVIEEGNE-TTVRISELPIRRWTQDYKEFLESISQG 934

Query: 709  YKKGKAPFIEDYTAHNDKTIVDFTINMSKDQMNTAKQEGFVTKFKLTTTLSTANMCLFDA 888
              K K PFIE +T H+D + VD  +++ ++ +  A+QEG + KFKLTT++ST+NM LFD 
Sbjct: 935  NDKAKDPFIEGFTQHSDHSTVDIIVHLPEENLMAARQEGLLKKFKLTTSISTSNMHLFDP 994

Query: 889  HGAIKKYDTPEQILEDFFYLFLAFYEERTIALRGELTKAILLLENKVKFIGEVREGNIRL 1068
             G IKKYDTPEQILE+FF+L L FYE+R   L   L   +L LENKV+FI  V  G I +
Sbjct: 995  KGVIKKYDTPEQILEEFFHLRLEFYEKRKKVLLDNLEMELLKLENKVRFILAVVNGEIIV 1054

Query: 1069 FNREDADICAELKAKGFAYLPKETK---PTTAGAVDHVGREE---------------YDY 1194
             NR  AD+  EL+ KGF   PK+TK   P  AGA++     E               Y+Y
Sbjct: 1055 SNRRRADLFLELQQKGFTPFPKKTKAQEPEVAGAIEDTEETEENSESASGNGARISDYEY 1114

Query: 1195 LLSMSFATFS--KFEQLKKEMDAKKQELEMITKSTYESLWVRDLEALDQQLEE 1347
            L+SM+  T +  + + L  + D    E+  +  ST  SLW++DL+AL+ +L E
Sbjct: 1115 LISMAIGTLTIERVQALCADRDKVNNEVAELRNSTPRSLWLKDLDALEMELGE 1167


>ref|XP_021824766.1| DNA topoisomerase 2 isoform X2 [Prunus avium]
          Length = 1469

 Score =  487 bits (1253), Expect = e-155
 Identities = 261/473 (55%), Positives = 333/473 (70%), Gaps = 24/473 (5%)
 Frame = +1

Query: 1    DLRRSIPSVVDGLNPGQRKILFCAFKKPIIQEIKVAQFSHYVSEHSAYHHGEASLVGTII 180
            DL+RSIPS+VDGL PGQRKILFC+FK+  ++E KVAQFS YVSEHSAYHHGE SL  TII
Sbjct: 696  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTII 755

Query: 181  GMAQNYVGSNNINLLQPIGQFGTRHMGGKEYLNDRCIFTQLSPITRYLFHKADELLLNYL 360
            GMAQ+YVGSNNINLLQP GQFGTR++GGK++ + R IFT+LSPITR+LF K D+ LL+YL
Sbjct: 756  GMAQDYVGSNNINLLQPNGQFGTRNLGGKDHASARYIFTRLSPITRFLFPKDDDRLLDYL 815

Query: 361  NDDGQSIEPARLMPIIPMVLVNGSEG-GLGCSSFISNYNPRDIIANLKRKLRGEAMVPMD 537
            ++DGQSIEP   +PIIP VLVNGSEG G G SS+I NYNPRDI+AN++R L GEAMVPMD
Sbjct: 816  DEDGQSIEPTWYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEAMVPMD 875

Query: 538  PWYKGFIGKIVTASKDTG--YTTIGKVEELKDGKGLRITELPVGRWTWEYEEFLKAASQ- 708
            PWY+GF G I    K++G  YT  G +EE  +   +RI+ELP+ RWT +Y+EFL++ SQ 
Sbjct: 876  PWYRGFSGTIEKTVKESGVSYTVCGIIEEGNE-TTVRISELPIRRWTQDYKEFLESISQG 934

Query: 709  YKKGKAPFIEDYTAHNDKTIVDFTINMSKDQMNTAKQEGFVTKFKLTTTLSTANMCLFDA 888
              K K PFIE +T H+D + VD  +++ ++ +  A+QEG + KFKLTT++ST+NM LFD 
Sbjct: 935  NDKAKDPFIEGFTQHSDHSTVDIIVHLPEENLMAARQEGLLKKFKLTTSISTSNMHLFDP 994

Query: 889  HGAIKKYDTPEQILEDFFYLFLAFYEERTIALRGELTKAILLLENKVKFIGEVREGNIRL 1068
             G IKKYDTPEQILEDFF+L L FYE+R   L   L   +L LENKV+FI  V  G I +
Sbjct: 995  KGVIKKYDTPEQILEDFFHLRLEFYEKRKKVLLDNLEMELLKLENKVRFILAVVNGEIIV 1054

Query: 1069 FNREDADICAELKAKGFAYLPKETK---PTTAGAVDHVGREE---------------YDY 1194
             NR  AD+  EL+ KGF   PK+TK   P  AGA++     E               Y+Y
Sbjct: 1055 SNRRRADLFLELQQKGFTPFPKKTKAQEPEVAGAIEDTEETEENSESASGNGARISDYEY 1114

Query: 1195 LLSMSFA--TFSKFEQLKKEMDAKKQELEMITKSTYESLWVRDLEALDQQLEE 1347
            L+SM+    T  + + L  + D    E+  +  ST  SLW++DL+AL+ +L E
Sbjct: 1115 LISMAIGSLTIERVQALCADRDKVNNEVAELRNSTPRSLWLKDLDALEMELGE 1167