BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Chrysanthemum21_contig00012639
         (2639 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_023770000.1| nicastrin [Lactuca sativa] >gi|1322387876|gb...   981   0.0  
ref|XP_022016107.1| nicastrin [Helianthus annuus] >gi|1191641428...   966   0.0  
gb|KVI03088.1| Nicastrin [Cynara cardunculus var. scolymus]           949   0.0  
ref|XP_023922018.1| nicastrin [Quercus suber] >gi|1336370009|gb|...   847   0.0  
gb|ONI17531.1| hypothetical protein PRUPE_3G165300 [Prunus persica]   846   0.0  
ref|XP_007217700.1| nicastrin [Prunus persica] >gi|1139783703|gb...   846   0.0  
ref|XP_007010305.2| PREDICTED: nicastrin [Theobroma cacao]            845   0.0  
ref|XP_021300371.1| nicastrin [Herrania umbratica]                    845   0.0  
ref|XP_002264144.1| PREDICTED: nicastrin [Vitis vinifera] >gi|29...   844   0.0  
gb|EOY19115.1| Zn-dependent exopeptidases superfamily protein is...   843   0.0  
ref|XP_018816638.1| PREDICTED: nicastrin isoform X2 [Juglans regia]   842   0.0  
ref|XP_018816637.1| PREDICTED: nicastrin isoform X1 [Juglans regia]   842   0.0  
dbj|GAV60467.1| Nicastrin domain-containing protein [Cephalotus ...   839   0.0  
ref|XP_021891327.1| nicastrin [Carica papaya]                         837   0.0  
ref|XP_019223514.1| PREDICTED: nicastrin isoform X2 [Nicotiana a...   835   0.0  
ref|XP_009758540.1| PREDICTED: nicastrin isoform X2 [Nicotiana s...   835   0.0  
gb|KDP25818.1| hypothetical protein JCGZ_22540 [Jatropha curcas]      835   0.0  
ref|XP_012086441.1| nicastrin [Jatropha curcas]                       835   0.0  
ref|XP_017248165.1| PREDICTED: nicastrin [Daucus carota subsp. s...   834   0.0  
ref|XP_006352434.1| PREDICTED: nicastrin isoform X2 [Solanum tub...   833   0.0  

>ref|XP_023770000.1| nicastrin [Lactuca sativa]
 gb|PLY80718.1| hypothetical protein LSAT_3X63981 [Lactuca sativa]
          Length = 663

 Score =  981 bits (2536), Expect = 0.0
 Identities = 492/640 (76%), Positives = 547/640 (85%), Gaps = 1/640 (0%)
 Frame = -1

Query: 2417 VPDLEKSMYTVLDGYPCVRLLNLSGEIGCANPSLDKVVAPIVRFKKGMELIRSSSVLVPL 2238
            VPDLEKSMY V+DGYPC+RLLNLSGEIGCANP LDKVVAPIVRFK G+EL++SSSVLVPL
Sbjct: 34   VPDLEKSMYMVIDGYPCIRLLNLSGEIGCANPGLDKVVAPIVRFKNGIELVKSSSVLVPL 93

Query: 2237 PXXXXXXXXXXXXXXFARNVAGILVESGARNQTHLKGSSPDTKFPQAEFAPYQNNKFEWN 2058
                           FARN+AG+LVESG +NQT+L  SSPD KFPQAEF+PYQNNKFEWN
Sbjct: 94   SDFDSLLSRVSSDSNFARNLAGVLVESGPQNQTNLTASSPDKKFPQAEFSPYQNNKFEWN 153

Query: 2057 PAGSGIMWKPYDFPVFLLSESSTETLQEIAVKNEDKKETYATKVTEFDLVMQTTKAGTHD 1878
            P GSGIMW  Y+FPVFLLSESST TLQEI+++NE+K ET+ATKVTEFDLVMQTTKAGTHD
Sbjct: 154  PTGSGIMWGLYEFPVFLLSESSTRTLQEISLENENK-ETHATKVTEFDLVMQTTKAGTHD 212

Query: 1877 SESCLNEGTCLPLGGYSVWSALPTTNVSASSKEKPIVLAVASMDSASFFRDKSLGADSPL 1698
            SESCL EGTCLPLGGYSV SA PTTNVS+S   KPI+L VASMDSASFFRDKSLGA SPL
Sbjct: 213  SESCLREGTCLPLGGYSVLSAFPTTNVSSS---KPILLTVASMDSASFFRDKSLGAQSPL 269

Query: 1697 SGLISLLAAVDALSRIEGSETLAKQIVFVVFTGEAWGYLGSRRFLFELDQHTDAVNGINN 1518
            SGLISLLAAVDALS I+  +TLAKQ+VFVVFTGEAWGYLGSRRFL ELD      NGINN
Sbjct: 270  SGLISLLAAVDALSHIDDLDTLAKQLVFVVFTGEAWGYLGSRRFLLELD------NGINN 323

Query: 1517 TLIETVIEVGSVGKGYDKGVKTFYAHTTGVSSATNETLKALQQAQDSLGTESIKYSAASK 1338
            TLIETVIEVGSVGKGYD+GVKTFYAHTTGVSSATN+TL ALQ AQDSLGT+SIK+S AS+
Sbjct: 324  TLIETVIEVGSVGKGYDQGVKTFYAHTTGVSSATNDTLNALQLAQDSLGTKSIKFSKASE 383

Query: 1337 SNPGIPPSSFMSFSKQKPHIAGVVLEDFDTSFTNKFYHSHLDDXXXXXXXXXXXXXXXXA 1158
            SNPGIPPSSFMSFSKQ PH +GVVLEDFDTSFTNKFYHSHLDD                A
Sbjct: 384  SNPGIPPSSFMSFSKQNPHTSGVVLEDFDTSFTNKFYHSHLDDQSNINSSAIVAAASLVA 443

Query: 1157 RTLYILASNSKDLSNSSINSIKVNTSLVDELLGCLLNCEPGLSCELVNHYISPFSTCPSH 978
            RTLYILA+N+K L++SS+N+IKVNTSLVD+LLGCLLNCEPGLSCELV +YI+PFS CPSH
Sbjct: 444  RTLYILANNNKTLNDSSLNTIKVNTSLVDQLLGCLLNCEPGLSCELVKNYITPFSICPSH 503

Query: 977  YVGVIQGEPSSEPYLGYVGDVSRFIWNYMADKTSIPSKNVSPCSENCSKTGGICIKQEID 798
            YVGV+QGEPSS+P+LGYV DVSRF+WN+MADKTS P +N +PCSENCS TGG+CIKQEID
Sbjct: 504  YVGVMQGEPSSQPFLGYVNDVSRFLWNFMADKTSTPLENATPCSENCSGTGGVCIKQEID 563

Query: 797  GKGECVMSTTRYIPAYSTRLKYDSS-GTWSVLPPNSSDQMGVTDPIWTESNWNIISLRVY 621
            GKG CV+S TRY+PAYSTRLKY+S+ GTW++LPPNSSD MG  DP+W ESNWN+I LRVY
Sbjct: 564  GKGICVISKTRYVPAYSTRLKYESALGTWTILPPNSSDPMGEADPVWAESNWNVIGLRVY 623

Query: 620  SVQGASYDHLVLMAGVAVTALSYLIIVVIKTFIAKALKQD 501
            SVQG  YD  V  +GVAVT  SY +I +IK FIAKALKQD
Sbjct: 624  SVQGGGYDRAVFWSGVAVTVFSYFLIKIIKAFIAKALKQD 663


>ref|XP_022016107.1| nicastrin [Helianthus annuus]
 gb|OTF93430.1| putative zn-dependent exopeptidases superfamily protein [Helianthus
            annuus]
          Length = 663

 Score =  966 bits (2496), Expect = 0.0
 Identities = 491/642 (76%), Positives = 550/642 (85%), Gaps = 3/642 (0%)
 Frame = -1

Query: 2417 VPDLEKSMYTVLDGYPCVRLLNLSGEIGCANPSLDKVVAPIVRFKKGMELIRSSSVLVPL 2238
            VPDLEKSMY V+DGYPCVRLLNLSGEIGCANP LDKVVAPIV+FK  +EL +SSS+LV  
Sbjct: 34   VPDLEKSMYKVIDGYPCVRLLNLSGEIGCANPGLDKVVAPIVKFKNDIELTQSSSLLVAS 93

Query: 2237 PXXXXXXXXXXXXXXFARNVAGILVESGARNQTHLKGSSPDTKFPQAEFAPYQNNKFEWN 2058
                           FARNVAG+LVESGA+NQTHLKGSSPD KFPQ EF+PYQN+KFEWN
Sbjct: 94   YDFESFLSRVSSDSKFARNVAGVLVESGAQNQTHLKGSSPDKKFPQVEFSPYQNSKFEWN 153

Query: 2057 PAGSGIMWKPYDFPVFLLSESSTETLQEIAVKNEDKKETYATKVTEFDLVMQTTKAGTHD 1878
            P GSGIMW  YDFPVFLLSESST++LQE+AVKNE+K +TYA +VTEFDLVMQTTKAGTHD
Sbjct: 154  PTGSGIMWGLYDFPVFLLSESSTQSLQEVAVKNENK-DTYAAEVTEFDLVMQTTKAGTHD 212

Query: 1877 SESCLNEGTCLPLGGYSVWSALPTTNVSASSKE--KPIVLAVASMDSASFFRDKSLGADS 1704
            SESCL E TCLPLGGYSVWSALPT N+S+SS +  KPI+LAVASMDSASFFRDKSLGA+S
Sbjct: 213  SESCLRERTCLPLGGYSVWSALPTVNISSSSSKNRKPIILAVASMDSASFFRDKSLGAES 272

Query: 1703 PLSGLISLLAAVDALSRIEGSETLAKQIVFVVFTGEAWGYLGSRRFLFELDQHTDAVNGI 1524
            PLSG+ISLLAAVDALSRIEG +TL+KQ+VFVVFTGEAWGYLGSRRFL ELDQHTDAVNGI
Sbjct: 273  PLSGMISLLAAVDALSRIEGLDTLSKQLVFVVFTGEAWGYLGSRRFLLELDQHTDAVNGI 332

Query: 1523 NNTLIETVIEVGSVGKGYDKGVKTFYAHTTGVSSATNETLKALQQAQDSLGTESIKYSAA 1344
            NNTLIETVIE+GSVGKGYD+GVKTFYAHT GVSSATN+TL A+Q+A+DSLGTESIKYS A
Sbjct: 333  NNTLIETVIELGSVGKGYDQGVKTFYAHTAGVSSATNKTLSAIQKARDSLGTESIKYSTA 392

Query: 1343 SKSNPGIPPSSFMSFSKQKPHIAGVVLEDFDTSFTNKFYHSHLDDXXXXXXXXXXXXXXX 1164
            S+SNPGIPPSSFMSF +Q P   GVVLEDFDTSFTNKFYHSHLDD               
Sbjct: 393  SESNPGIPPSSFMSFLRQNPLTPGVVLEDFDTSFTNKFYHSHLDDLSNINSSAIAAAASL 452

Query: 1163 XARTLYILASNSKDLSNSSINSIKVNTSLVDELLGCLLNCEPGLSCELVNHYISPFSTCP 984
             ARTLY+LASN+ DLS+SS+ SIKVNTSLV+EL+GCLL+CEPGLSCELVN YISP S CP
Sbjct: 453  VARTLYVLASNNNDLSDSSLKSIKVNTSLVEELVGCLLSCEPGLSCELVNRYISPSSACP 512

Query: 983  SHYVGVIQGEPSSEPYLGYVGDVSRFIWNYMADKTSIPSKNVSPCSENC-SKTGGICIKQ 807
            SHYVGVIQG+P SEPY GYV DV RF+WN+MAD T   S N  PCSENC S+TGG+C+K+
Sbjct: 513  SHYVGVIQGDP-SEPYYGYVNDVPRFVWNFMADMT---STNGGPCSENCSSQTGGVCVKK 568

Query: 806  EIDGKGECVMSTTRYIPAYSTRLKYDSSGTWSVLPPNSSDQMGVTDPIWTESNWNIISLR 627
            EIDGKG C +STTRY+PAYSTRLKY+S  +W+VLP + +      DP+WTESNWN ISLR
Sbjct: 569  EIDGKGVCAISTTRYVPAYSTRLKYESE-SWTVLPSDPA------DPVWTESNWNTISLR 621

Query: 626  VYSVQGASYDHLVLMAGVAVTALSYLIIVVIKTFIAKALKQD 501
            VYSVQGA+YDHLVL+AGV+VTAL+YL+IVVIK FIAKALKQD
Sbjct: 622  VYSVQGAAYDHLVLVAGVSVTALAYLLIVVIKAFIAKALKQD 663


>gb|KVI03088.1| Nicastrin [Cynara cardunculus var. scolymus]
          Length = 631

 Score =  949 bits (2454), Expect = 0.0
 Identities = 482/639 (75%), Positives = 528/639 (82%)
 Frame = -1

Query: 2417 VPDLEKSMYTVLDGYPCVRLLNLSGEIGCANPSLDKVVAPIVRFKKGMELIRSSSVLVPL 2238
            VPDLEKSMY VLDGYPCVRLLNLSGEIGCANP LDKVVAPIVRFK G+EL+RS+++LVPL
Sbjct: 34   VPDLEKSMYMVLDGYPCVRLLNLSGEIGCANPGLDKVVAPIVRFKNGIELVRSTTILVPL 93

Query: 2237 PXXXXXXXXXXXXXXFARNVAGILVESGARNQTHLKGSSPDTKFPQAEFAPYQNNKFEWN 2058
                           FARNVAG+LVESG +NQTHL GSSPD KFPQAEFAPY+NNKFEWN
Sbjct: 94   YDFDRLLSRVSSDSNFARNVAGVLVESGTQNQTHLTGSSPDKKFPQAEFAPYENNKFEWN 153

Query: 2057 PAGSGIMWKPYDFPVFLLSESSTETLQEIAVKNEDKKETYATKVTEFDLVMQTTKAGTHD 1878
            P GSG MW+ YDFPVFLLSESST+TLQEIAVKNE+KKETYA  VTEFDLVMQ        
Sbjct: 154  PTGSGSMWRRYDFPVFLLSESSTQTLQEIAVKNENKKETYAADVTEFDLVMQG------- 206

Query: 1877 SESCLNEGTCLPLGGYSVWSALPTTNVSASSKEKPIVLAVASMDSASFFRDKSLGADSPL 1698
                            SVWSALPTTNVSASS+EKP+VL VASMDSASFFRDKSLGADSP+
Sbjct: 207  ----------------SVWSALPTTNVSASSREKPVVLTVASMDSASFFRDKSLGADSPI 250

Query: 1697 SGLISLLAAVDALSRIEGSETLAKQIVFVVFTGEAWGYLGSRRFLFELDQHTDAVNGINN 1518
            SG+ISLLAAVDALSRIE  +TLAKQ+VFVVFTGEAWGYLGSRRFL ELDQHTDAV+GINN
Sbjct: 251  SGMISLLAAVDALSRIEDLDTLAKQLVFVVFTGEAWGYLGSRRFLLELDQHTDAVHGINN 310

Query: 1517 TLIETVIEVGSVGKGYDKGVKTFYAHTTGVSSATNETLKALQQAQDSLGTESIKYSAASK 1338
            TLIETVIEVGSVGKGYD+GVKTFYAHTTGVSSATNETLKALQQA+DSLGTESIKYS ASK
Sbjct: 311  TLIETVIEVGSVGKGYDQGVKTFYAHTTGVSSATNETLKALQQARDSLGTESIKYSTASK 370

Query: 1337 SNPGIPPSSFMSFSKQKPHIAGVVLEDFDTSFTNKFYHSHLDDXXXXXXXXXXXXXXXXA 1158
            SNPGIPPSSFMSFS+Q PH AGVVLEDFD++FTNKFYHSHLDD                A
Sbjct: 371  SNPGIPPSSFMSFSRQNPHAAGVVLEDFDSAFTNKFYHSHLDDISNINSSAIVAAASLVA 430

Query: 1157 RTLYILASNSKDLSNSSINSIKVNTSLVDELLGCLLNCEPGLSCELVNHYISPFSTCPSH 978
            RTLYILAS++KDLS+SS+N++ VNTSLVDELLGCLL+CEPGLSCELV  YI+P STCPSH
Sbjct: 431  RTLYILASDNKDLSSSSLNAVNVNTSLVDELLGCLLSCEPGLSCELVKRYITPSSTCPSH 490

Query: 977  YVGVIQGEPSSEPYLGYVGDVSRFIWNYMADKTSIPSKNVSPCSENCSKTGGICIKQEID 798
            YVGVIQG+PS EP+LGYVGDV RF+WN+MAD+TS P K+VSPCSENCS +GG+CIKQEID
Sbjct: 491  YVGVIQGDPSLEPFLGYVGDVPRFVWNFMADRTSTPLKDVSPCSENCSMSGGVCIKQEID 550

Query: 797  GKGECVMSTTRYIPAYSTRLKYDSSGTWSVLPPNSSDQMGVTDPIWTESNWNIISLRVYS 618
            GKG CV STT                  SVLPPNSSD MG  DP+W ESNWN+I LRVYS
Sbjct: 551  GKGICVTSTT------------------SVLPPNSSDLMGAADPVWAESNWNVIGLRVYS 592

Query: 617  VQGASYDHLVLMAGVAVTALSYLIIVVIKTFIAKALKQD 501
            VQGA+YD L+LMAGV VTALSYL+IV++K  IAKALKQD
Sbjct: 593  VQGAAYDRLILMAGVVVTALSYLLIVIVKAIIAKALKQD 631


>ref|XP_023922018.1| nicastrin [Quercus suber]
 gb|POE98469.1| nicastrin [Quercus suber]
          Length = 671

 Score =  847 bits (2188), Expect = 0.0
 Identities = 418/640 (65%), Positives = 503/640 (78%), Gaps = 1/640 (0%)
 Frame = -1

Query: 2417 VPDLEKSMYTVLDGYPCVRLLNLSGEIGCANPSLDKVVAPIVRFKKGMELIRSSSVLVPL 2238
            VPDL+KSMY V+DGYPCVRLLNLSG IGC+NP    VVAPIVR++   +L +SSS+LV L
Sbjct: 34   VPDLQKSMYKVIDGYPCVRLLNLSGPIGCSNPGRQVVVAPIVRYQNATQLSQSSSILVSL 93

Query: 2237 PXXXXXXXXXXXXXXFARNVAGILVESGARNQTHLKGSSPDTKFPQAEFAPYQNNKFEWN 2058
                           FA N+AG++VESG   Q  LKG SP  KFPQAEFAPYQN  +EWN
Sbjct: 94   DEFQSFITRIWNDSSFASNIAGVIVESGTEIQNKLKGFSPAHKFPQAEFAPYQNTNYEWN 153

Query: 2057 PAGSGIMWKPYDFPVFLLSESSTETLQEIAVKNEDKKETYATKVTEFDLVMQTTKAGTHD 1878
            P GSGIMWK Y+FPVFLLS SST TL+E A  NE   + Y T V EFDLVMQ+TKAGTHD
Sbjct: 154  PIGSGIMWKAYNFPVFLLSGSSTLTLEEAATNNEKSMKAYTTDVAEFDLVMQSTKAGTHD 213

Query: 1877 SESCLNEGTCLPLGGYSVWSALPTTNVSASSKEKPIVLAVASMDSASFFRDKSLGADSPL 1698
            SESCL EG CLPLGGYSVWS+LP  NVS+S + KP++L VASMDSASFFRDKSLGADSPL
Sbjct: 214  SESCLKEGACLPLGGYSVWSSLPPINVSSSEQSKPVILTVASMDSASFFRDKSLGADSPL 273

Query: 1697 SGLISLLAAVDALSRIEGSETLAKQIVFVVFTGEAWGYLGSRRFLFELDQHTDAVNGINN 1518
            SGLISLLAAVDALSR++G + L KQ+VF+VFTGEAWGYLGSRRFL ELD  +DAV+G++N
Sbjct: 274  SGLISLLAAVDALSRVDGLDDLTKQLVFIVFTGEAWGYLGSRRFLHELDLQSDAVSGLDN 333

Query: 1517 TLIETVIEVGSVGKGYDKGVKTFYAHTTGVSSATNETLKALQQAQDSLGTESIKYSAASK 1338
            +LIE V+E+GS+GKG+++GV  FYAH TG SSATNETL AL+QAQDSL +E I  SAA+ 
Sbjct: 334  SLIEMVMEIGSIGKGFNQGVNKFYAHITGASSATNETLDALEQAQDSLKSEHIICSAANA 393

Query: 1337 SNPGIPPSSFMSFSKQKPHIAGVVLEDFDTSFTNKFYHSHLDDXXXXXXXXXXXXXXXXA 1158
            SNPGIPPSS M+F ++  H +GVVLEDF++ F+NKFYHSHLDD                A
Sbjct: 394  SNPGIPPSSLMAFLQKNSHTSGVVLEDFNSVFSNKFYHSHLDDISNINSSAVVAAASLVA 453

Query: 1157 RTLYILASNSKDLSNSSINSIKVNTSLVDELLGCLLNCEPGLSCELVNHYISPFSTCPSH 978
            RTLYILAS++  LS+S++ +I VN SLV+EL+GCL +C+PGLSC LV +YISP +TCPSH
Sbjct: 454  RTLYILASDNNTLSSSALTAINVNVSLVEELMGCLFDCDPGLSCNLVKNYISPTNTCPSH 513

Query: 977  YVGVIQGEPSSEPYLGYVGDVSRFIWNYMADKTSIPSKN-VSPCSENCSKTGGICIKQEI 801
            YVGVI  EPSS PYLGYV DVSRF+WN++AD+TSIP +N  S CS+ C+  G +C++ E 
Sbjct: 514  YVGVILDEPSSTPYLGYVDDVSRFLWNFLADRTSIPRENSSSTCSKGCN-NGEVCVRAET 572

Query: 800  DGKGECVMSTTRYIPAYSTRLKYDSSGTWSVLPPNSSDQMGVTDPIWTESNWNIISLRVY 621
            +GKG CV+STTRY+PAYSTRLK+DS   W VLPPNSSD MG+ DP+WTESNWN I LRVY
Sbjct: 573  EGKGVCVISTTRYVPAYSTRLKFDSE-AWIVLPPNSSDPMGMVDPVWTESNWNAIGLRVY 631

Query: 620  SVQGASYDHLVLMAGVAVTALSYLIIVVIKTFIAKALKQD 501
            +VQ  +YD+LVL+ G+AVT L+YL IV+ + FI K+LK+D
Sbjct: 632  TVQNGAYDNLVLLGGIAVTVLAYLAIVITRAFITKSLKRD 671


>gb|ONI17531.1| hypothetical protein PRUPE_3G165300 [Prunus persica]
          Length = 645

 Score =  846 bits (2185), Expect = 0.0
 Identities = 420/641 (65%), Positives = 502/641 (78%), Gaps = 2/641 (0%)
 Frame = -1

Query: 2417 VPDLEKSMYTVLDGYPCVRLLNLSGEIGCANPSLDKVVAPIVRFKKGMELIRSSSVLVPL 2238
            VPDL+ SMY  LDGYPCVRLLNLSG IGC+NP   KVVAPI+R     EL + S+VL+ +
Sbjct: 5    VPDLQSSMYMTLDGYPCVRLLNLSGVIGCSNPGRVKVVAPIIRLNNATELSQLSAVLLSV 64

Query: 2237 PXXXXXXXXXXXXXXFARNVAGILVESGARNQTHLKGSSPDTKFPQAEFAPYQNNKFEWN 2058
                           FA+NVAGILVES    Q  LKG SPD KFPQ+EFAPYQ+  +EWN
Sbjct: 65   DEIQSFLTRILNDSTFAKNVAGILVESSPEFQNKLKGFSPDQKFPQSEFAPYQSINYEWN 124

Query: 2057 PAGSGIMWKPYDFPVFLLSESSTETLQEIAVKNEDKKETYATKVTEFDLVMQTTKAGTHD 1878
            P GSGIMW PY+FPVFLLS+SST TLQE A+KNE   ++Y   V EFDLVMQT KAGTHD
Sbjct: 125  PIGSGIMWNPYNFPVFLLSQSSTLTLQEAAIKNEKNIKSYTADVAEFDLVMQTMKAGTHD 184

Query: 1877 SESCLNEGTCLPLGGYSVWSALPTTNVSASSKEKPIVLAVASMDSASFFRDKSLGADSPL 1698
            SESCL E TCLPLGGYSVWS+LP  N S+S + KPI+L VASMDSASFFRDK LGADSP+
Sbjct: 185  SESCLKENTCLPLGGYSVWSSLPPINFSSSEQSKPIILVVASMDSASFFRDKGLGADSPI 244

Query: 1697 SGLISLLAAVDALSRIEGSETLAKQIVFVVFTGEAWGYLGSRRFLFELDQHTDAVNGINN 1518
            SGLISLLAAVDALS ++G +   KQ+VF+VFTGEAWGYLGSRRFL ELD  +DAV+G+N 
Sbjct: 245  SGLISLLAAVDALSHVDGLDDFNKQLVFIVFTGEAWGYLGSRRFLLELDLQSDAVSGLNY 304

Query: 1517 TLIETVIEVGSVGKGYDKGVKTFYAHTTGVSSATNETLKALQQAQDSLGTESIKYSAASK 1338
            +LIE V+E+GSVGKG ++GVK F+ HTTGVSSATNETL AL++AQDS+ +ES   S+A+ 
Sbjct: 305  SLIEKVVEIGSVGKGLNQGVKNFFVHTTGVSSATNETLDALKRAQDSVKSESFTISSANA 364

Query: 1337 SNPGIPPSSFMSFSKQKPHIAGVVLEDFDTSFTNKFYHSHLDDXXXXXXXXXXXXXXXXA 1158
            SNPGIPPSS M+F ++    +GVVLEDFDT FTNKFY+SHLDD                A
Sbjct: 365  SNPGIPPSSLMTFLRKNSLTSGVVLEDFDTVFTNKFYNSHLDDISNVNSSAIVAAASLVA 424

Query: 1157 RTLYILASNSKDLSNSSINSIKVNTSLVDELLGCLLNCEPGLSCELVNHYISPFSTCPSH 978
            RTLYILAS++K+LS+S+I SI VN SLV+EL+GCLL+CEPGLSCELV  YISP +TCPSH
Sbjct: 425  RTLYILASDNKNLSSSAITSINVNVSLVEELMGCLLDCEPGLSCELVKSYISPANTCPSH 484

Query: 977  YVGVIQGEPSSEPYLGYVGDVSRFIWNYMADKTSIPSKN-VSPCSENCSKTGGICIKQEI 801
            YVGVI GEPSS PYLGYV D+SRF+WN++A+KTSIP KN  S CS++CS  G +CI+ E 
Sbjct: 485  YVGVILGEPSSPPYLGYVDDISRFVWNFLAEKTSIPRKNGSSVCSQDCSNEGEVCIRAET 544

Query: 800  DGKGECVMSTTRYIPAYSTRLKYDS-SGTWSVLPPNSSDQMGVTDPIWTESNWNIISLRV 624
            +GKG CV+STTRY+PAYSTRLKY+S SGTW+VLPPN+SD MG+ D +WTESNW+ I LRV
Sbjct: 545  EGKGVCVVSTTRYVPAYSTRLKYESESGTWNVLPPNNSDPMGLVDAVWTESNWDTIGLRV 604

Query: 623  YSVQGASYDHLVLMAGVAVTALSYLIIVVIKTFIAKALKQD 501
            Y+VQ AS+D LVL+  +A+T LS   IV+ K F+ KA+K+D
Sbjct: 605  YTVQNASFDRLVLLGSIAITVLSCFAIVITKAFVTKAVKRD 645


>ref|XP_007217700.1| nicastrin [Prunus persica]
 gb|ONI17530.1| hypothetical protein PRUPE_3G165300 [Prunus persica]
          Length = 670

 Score =  846 bits (2185), Expect = 0.0
 Identities = 420/641 (65%), Positives = 502/641 (78%), Gaps = 2/641 (0%)
 Frame = -1

Query: 2417 VPDLEKSMYTVLDGYPCVRLLNLSGEIGCANPSLDKVVAPIVRFKKGMELIRSSSVLVPL 2238
            VPDL+ SMY  LDGYPCVRLLNLSG IGC+NP   KVVAPI+R     EL + S+VL+ +
Sbjct: 30   VPDLQSSMYMTLDGYPCVRLLNLSGVIGCSNPGRVKVVAPIIRLNNATELSQLSAVLLSV 89

Query: 2237 PXXXXXXXXXXXXXXFARNVAGILVESGARNQTHLKGSSPDTKFPQAEFAPYQNNKFEWN 2058
                           FA+NVAGILVES    Q  LKG SPD KFPQ+EFAPYQ+  +EWN
Sbjct: 90   DEIQSFLTRILNDSTFAKNVAGILVESSPEFQNKLKGFSPDQKFPQSEFAPYQSINYEWN 149

Query: 2057 PAGSGIMWKPYDFPVFLLSESSTETLQEIAVKNEDKKETYATKVTEFDLVMQTTKAGTHD 1878
            P GSGIMW PY+FPVFLLS+SST TLQE A+KNE   ++Y   V EFDLVMQT KAGTHD
Sbjct: 150  PIGSGIMWNPYNFPVFLLSQSSTLTLQEAAIKNEKNIKSYTADVAEFDLVMQTMKAGTHD 209

Query: 1877 SESCLNEGTCLPLGGYSVWSALPTTNVSASSKEKPIVLAVASMDSASFFRDKSLGADSPL 1698
            SESCL E TCLPLGGYSVWS+LP  N S+S + KPI+L VASMDSASFFRDK LGADSP+
Sbjct: 210  SESCLKENTCLPLGGYSVWSSLPPINFSSSEQSKPIILVVASMDSASFFRDKGLGADSPI 269

Query: 1697 SGLISLLAAVDALSRIEGSETLAKQIVFVVFTGEAWGYLGSRRFLFELDQHTDAVNGINN 1518
            SGLISLLAAVDALS ++G +   KQ+VF+VFTGEAWGYLGSRRFL ELD  +DAV+G+N 
Sbjct: 270  SGLISLLAAVDALSHVDGLDDFNKQLVFIVFTGEAWGYLGSRRFLLELDLQSDAVSGLNY 329

Query: 1517 TLIETVIEVGSVGKGYDKGVKTFYAHTTGVSSATNETLKALQQAQDSLGTESIKYSAASK 1338
            +LIE V+E+GSVGKG ++GVK F+ HTTGVSSATNETL AL++AQDS+ +ES   S+A+ 
Sbjct: 330  SLIEKVVEIGSVGKGLNQGVKNFFVHTTGVSSATNETLDALKRAQDSVKSESFTISSANA 389

Query: 1337 SNPGIPPSSFMSFSKQKPHIAGVVLEDFDTSFTNKFYHSHLDDXXXXXXXXXXXXXXXXA 1158
            SNPGIPPSS M+F ++    +GVVLEDFDT FTNKFY+SHLDD                A
Sbjct: 390  SNPGIPPSSLMTFLRKNSLTSGVVLEDFDTVFTNKFYNSHLDDISNVNSSAIVAAASLVA 449

Query: 1157 RTLYILASNSKDLSNSSINSIKVNTSLVDELLGCLLNCEPGLSCELVNHYISPFSTCPSH 978
            RTLYILAS++K+LS+S+I SI VN SLV+EL+GCLL+CEPGLSCELV  YISP +TCPSH
Sbjct: 450  RTLYILASDNKNLSSSAITSINVNVSLVEELMGCLLDCEPGLSCELVKSYISPANTCPSH 509

Query: 977  YVGVIQGEPSSEPYLGYVGDVSRFIWNYMADKTSIPSKN-VSPCSENCSKTGGICIKQEI 801
            YVGVI GEPSS PYLGYV D+SRF+WN++A+KTSIP KN  S CS++CS  G +CI+ E 
Sbjct: 510  YVGVILGEPSSPPYLGYVDDISRFVWNFLAEKTSIPRKNGSSVCSQDCSNEGEVCIRAET 569

Query: 800  DGKGECVMSTTRYIPAYSTRLKYDS-SGTWSVLPPNSSDQMGVTDPIWTESNWNIISLRV 624
            +GKG CV+STTRY+PAYSTRLKY+S SGTW+VLPPN+SD MG+ D +WTESNW+ I LRV
Sbjct: 570  EGKGVCVVSTTRYVPAYSTRLKYESESGTWNVLPPNNSDPMGLVDAVWTESNWDTIGLRV 629

Query: 623  YSVQGASYDHLVLMAGVAVTALSYLIIVVIKTFIAKALKQD 501
            Y+VQ AS+D LVL+  +A+T LS   IV+ K F+ KA+K+D
Sbjct: 630  YTVQNASFDRLVLLGSIAITVLSCFAIVITKAFVTKAVKRD 670


>ref|XP_007010305.2| PREDICTED: nicastrin [Theobroma cacao]
          Length = 666

 Score =  845 bits (2184), Expect = 0.0
 Identities = 414/639 (64%), Positives = 497/639 (77%)
 Frame = -1

Query: 2417 VPDLEKSMYTVLDGYPCVRLLNLSGEIGCANPSLDKVVAPIVRFKKGMELIRSSSVLVPL 2238
            VPDL+KSMY V+DGYPCVRL+NLSGEIGC+NP  DKVVAPIV++K   EL + S++L+ +
Sbjct: 30   VPDLQKSMYMVVDGYPCVRLVNLSGEIGCSNPGRDKVVAPIVKYKDTKELAQPSAILLSM 89

Query: 2237 PXXXXXXXXXXXXXXFARNVAGILVESGARNQTHLKGSSPDTKFPQAEFAPYQNNKFEWN 2058
                           FARNV G+LVESG   Q  LKG SP  KFPQAEFAPY N  +EWN
Sbjct: 90   DDVQGFFSRVSNDSSFARNVGGVLVESGIEIQNKLKGFSPAQKFPQAEFAPYHNTSYEWN 149

Query: 2057 PAGSGIMWKPYDFPVFLLSESSTETLQEIAVKNEDKKETYATKVTEFDLVMQTTKAGTHD 1878
            P G+G MWK Y+FPVFLLSESST TLQE+ +KNE  ++ Y T V EFDLVMQTTK GTHD
Sbjct: 150  PIGNGDMWKSYNFPVFLLSESSTSTLQEVTMKNEKTEKAYTTNVAEFDLVMQTTKVGTHD 209

Query: 1877 SESCLNEGTCLPLGGYSVWSALPTTNVSASSKEKPIVLAVASMDSASFFRDKSLGADSPL 1698
            SESCL E TCLPLGGYSVWSA+P  N S+S++ KPI+L VASMD+ASFFRDKSLGADSP+
Sbjct: 210  SESCLKEETCLPLGGYSVWSAVPPINSSSSNQSKPIILTVASMDAASFFRDKSLGADSPI 269

Query: 1697 SGLISLLAAVDALSRIEGSETLAKQIVFVVFTGEAWGYLGSRRFLFELDQHTDAVNGINN 1518
            SG+ISLLAAVDALSR++G + L KQ+VF+VFTGEAWGYLGSRRFL ELDQ +DAV G+N+
Sbjct: 270  SGVISLLAAVDALSRVDGLDDLNKQLVFLVFTGEAWGYLGSRRFLLELDQQSDAVRGLNS 329

Query: 1517 TLIETVIEVGSVGKGYDKGVKTFYAHTTGVSSATNETLKALQQAQDSLGTESIKYSAASK 1338
            TL+E V+E+GS GKG+ +G KTF+AHT  VSS  NE L AL+ AQ+SL +E +  S A+ 
Sbjct: 330  TLVELVMEIGSTGKGFSQGNKTFFAHTE-VSSGANEALDALKLAQESLKSEGVTISTANS 388

Query: 1337 SNPGIPPSSFMSFSKQKPHIAGVVLEDFDTSFTNKFYHSHLDDXXXXXXXXXXXXXXXXA 1158
            SNPGIPPSS M+F ++    +G+VLEDFD+ F NKFYHSHLDD                A
Sbjct: 389  SNPGIPPSSLMAFLRKNSSTSGIVLEDFDSIFVNKFYHSHLDDSSNINSSAIVAAASLVA 448

Query: 1157 RTLYILASNSKDLSNSSINSIKVNTSLVDELLGCLLNCEPGLSCELVNHYISPFSTCPSH 978
            RTLYILASN+KDL++S+I++I VN SLV+EL+ C+L+C PGLSCELV  YIS  +TCPSH
Sbjct: 449  RTLYILASNNKDLTSSAISTISVNASLVEELISCMLDCNPGLSCELVKSYISSTNTCPSH 508

Query: 977  YVGVIQGEPSSEPYLGYVGDVSRFIWNYMADKTSIPSKNVSPCSENCSKTGGICIKQEID 798
            YVGV+ GEPSS PY   V DVSRF+WN++AD+TSIP  N S CS +C K GG+CI+ E D
Sbjct: 509  YVGVVLGEPSSTPYPSQVDDVSRFLWNFLADRTSIPKGNTSVCSHDCGKNGGVCIRAETD 568

Query: 797  GKGECVMSTTRYIPAYSTRLKYDSSGTWSVLPPNSSDQMGVTDPIWTESNWNIISLRVYS 618
            GKG CV+STTRY+PAYSTRLK+D SGTW VLPPNS+D MG+ DP+WTESNWN I LRVY+
Sbjct: 569  GKGVCVISTTRYVPAYSTRLKFD-SGTWKVLPPNSTDPMGMLDPVWTESNWNTIGLRVYT 627

Query: 617  VQGASYDHLVLMAGVAVTALSYLIIVVIKTFIAKALKQD 501
            VQ  +YD LVL+ GVAVT LSY  IV+ + +I KALKQD
Sbjct: 628  VQDPAYDRLVLLGGVAVTVLSYFAIVLTRAYITKALKQD 666


>ref|XP_021300371.1| nicastrin [Herrania umbratica]
          Length = 666

 Score =  845 bits (2182), Expect = 0.0
 Identities = 412/639 (64%), Positives = 497/639 (77%)
 Frame = -1

Query: 2417 VPDLEKSMYTVLDGYPCVRLLNLSGEIGCANPSLDKVVAPIVRFKKGMELIRSSSVLVPL 2238
            VPDL+KSMY V+DGYPCVRL+NLSGEIGC+NP  DKVVAPIV++K   EL + S++L+ +
Sbjct: 30   VPDLQKSMYMVVDGYPCVRLVNLSGEIGCSNPGRDKVVAPIVKYKDTRELAQPSAILLSM 89

Query: 2237 PXXXXXXXXXXXXXXFARNVAGILVESGARNQTHLKGSSPDTKFPQAEFAPYQNNKFEWN 2058
                           FA NV G+LVESG   Q  LKG SP  KFPQAEFAPY N  +EWN
Sbjct: 90   DDVQGFFSRISNDSSFASNVGGVLVESGVEIQNKLKGFSPAQKFPQAEFAPYHNTSYEWN 149

Query: 2057 PAGSGIMWKPYDFPVFLLSESSTETLQEIAVKNEDKKETYATKVTEFDLVMQTTKAGTHD 1878
            P G+G+MWK Y+FPVFLLSESST TLQE+ +KNE  ++ YAT V EFDLVMQTTK GTHD
Sbjct: 150  PIGNGVMWKSYNFPVFLLSESSTSTLQEVTMKNEKTEKVYATNVAEFDLVMQTTKVGTHD 209

Query: 1877 SESCLNEGTCLPLGGYSVWSALPTTNVSASSKEKPIVLAVASMDSASFFRDKSLGADSPL 1698
            SESCL E TCLPLGGYSVWSA+P  N S+S+  KPI+L VASMD+ASFFRDKSLGADSP+
Sbjct: 210  SESCLKEETCLPLGGYSVWSAVPPINSSSSNLSKPIILTVASMDAASFFRDKSLGADSPI 269

Query: 1697 SGLISLLAAVDALSRIEGSETLAKQIVFVVFTGEAWGYLGSRRFLFELDQHTDAVNGINN 1518
            SG+ISLLAAVDALS ++G + L KQ+VF+VFTGEAWGYLGSRRFL ELDQ +DAV G+N+
Sbjct: 270  SGVISLLAAVDALSHVDGLDDLNKQLVFLVFTGEAWGYLGSRRFLLELDQQSDAVRGLNS 329

Query: 1517 TLIETVIEVGSVGKGYDKGVKTFYAHTTGVSSATNETLKALQQAQDSLGTESIKYSAASK 1338
            TL+E V+E+GS G+G  +G KTF+AHT  VSS  NE L AL+ AQ+SL +E++  S A+ 
Sbjct: 330  TLVELVMEIGSTGRGLSQGNKTFFAHTE-VSSGANEALDALKLAQESLKSEAVTISTANS 388

Query: 1337 SNPGIPPSSFMSFSKQKPHIAGVVLEDFDTSFTNKFYHSHLDDXXXXXXXXXXXXXXXXA 1158
            SNPGIPPSS M+F ++    +G+VLEDFD+ F NKFYHSHLDD                A
Sbjct: 389  SNPGIPPSSLMAFLRKNSSTSGIVLEDFDSIFANKFYHSHLDDSSNINSSAIVAAASLVA 448

Query: 1157 RTLYILASNSKDLSNSSINSIKVNTSLVDELLGCLLNCEPGLSCELVNHYISPFSTCPSH 978
            RTLYILASN+KDL++S++ +I VN SLV+EL+GC+L+C PGLSCELV  YIS  +TCPSH
Sbjct: 449  RTLYILASNNKDLTSSALTTISVNASLVEELIGCMLDCNPGLSCELVKSYISSTNTCPSH 508

Query: 977  YVGVIQGEPSSEPYLGYVGDVSRFIWNYMADKTSIPSKNVSPCSENCSKTGGICIKQEID 798
            YVGV+ GEPSS PY   V DVSRF+WN++AD+TSIP  N S CS +C K GG+CI+ E D
Sbjct: 509  YVGVVLGEPSSTPYPSQVDDVSRFLWNFLADRTSIPKGNTSVCSHDCGKNGGVCIRAETD 568

Query: 797  GKGECVMSTTRYIPAYSTRLKYDSSGTWSVLPPNSSDQMGVTDPIWTESNWNIISLRVYS 618
            GKG CV+STTRY+PAYSTRLK+D SGTW VLPPNS+D MG+ DP+WTESNWN I LRVY+
Sbjct: 569  GKGVCVISTTRYVPAYSTRLKFD-SGTWKVLPPNSTDPMGMLDPVWTESNWNTIGLRVYT 627

Query: 617  VQGASYDHLVLMAGVAVTALSYLIIVVIKTFIAKALKQD 501
            VQ A+YD LVL+ G+AVT LSY  IV+ + +I KALKQD
Sbjct: 628  VQDAAYDRLVLLGGIAVTVLSYFAIVLTRAYITKALKQD 666


>ref|XP_002264144.1| PREDICTED: nicastrin [Vitis vinifera]
 emb|CBI33472.3| unnamed protein product, partial [Vitis vinifera]
          Length = 671

 Score =  844 bits (2180), Expect = 0.0
 Identities = 419/640 (65%), Positives = 502/640 (78%), Gaps = 1/640 (0%)
 Frame = -1

Query: 2417 VPDLEKSMYTVLDGYPCVRLLNLSGEIGCANPSLDKVVAPIVRFKKGMELIRSSSVLVPL 2238
            VPDLEKSMY V+DGYPCVRLLNLSGEIGC+NP  +KVVAPIVRFK    L +SS++LV L
Sbjct: 33   VPDLEKSMYMVVDGYPCVRLLNLSGEIGCSNPGREKVVAPIVRFKNVNVLAQSSAILVSL 92

Query: 2237 PXXXXXXXXXXXXXXFARNVAGILVESGARNQTHLKGSSPDTKFPQAEFAPYQNNKFEWN 2058
                           FARNV G+LVES + +Q  LKG SP  KFPQAEFAPYQ+  +EWN
Sbjct: 93   DEIQSFFTRLSHDSNFARNVGGVLVESVSASQNKLKGFSPVEKFPQAEFAPYQSINYEWN 152

Query: 2057 PAGSGIMWKPYDFPVFLLSESSTETLQEIAVKNEDKKETYATKVTEFDLVMQTTKAGTHD 1878
            P GSGIMW  Y+FP+FLLS+SST TLQE+A+KNE  K+ Y   V EFDLVMQTTK+GTHD
Sbjct: 153  PIGSGIMWNTYNFPMFLLSQSSTLTLQEVAIKNEKNKKAYTADVAEFDLVMQTTKSGTHD 212

Query: 1877 SESCLNEGTCLPLGGYSVWSALPTTNVSASSKEKPIVLAVASMDSASFFRDKSLGADSPL 1698
            SESCL E TCLPLGGYSVWS+LP  NVS+S + KP++L VASMDSASFFRDKSLGADSP+
Sbjct: 213  SESCLKEETCLPLGGYSVWSSLPPINVSSSDQSKPVILTVASMDSASFFRDKSLGADSPI 272

Query: 1697 SGLISLLAAVDALSRIEGSETLAKQIVFVVFTGEAWGYLGSRRFLFELDQHTDAVNGINN 1518
            SGLISL+AAVDALS ++G   L+KQ+VF+VFTGEAWGYLGSRRFL ELD H+D V GI++
Sbjct: 273  SGLISLMAAVDALSHLDGLNDLSKQLVFLVFTGEAWGYLGSRRFLLELDLHSDFVKGIDS 332

Query: 1517 TLIETVIEVGSVGKGYDKGVKTFYAHTTGVSSATNETLKALQQAQDSLGTESIKYSAASK 1338
            TLIE V+E+GSVGKG+ +GVKTF+AH   VSS TNETL ALQQA+DSL +ESI  S A+ 
Sbjct: 333  TLIEMVMEIGSVGKGFSQGVKTFFAHVAEVSSVTNETLNALQQAKDSLKSESIMISTANS 392

Query: 1337 SNPGIPPSSFMSFSKQKPHIAGVVLEDFDTSFTNKFYHSHLDDXXXXXXXXXXXXXXXXA 1158
            SNPGIPPSS MSF ++    +G+VLEDFD +F N+FYHSHLDD                A
Sbjct: 393  SNPGIPPSSLMSFLRKNSSTSGIVLEDFDATFANQFYHSHLDDLSNVNSSAIVAAASLVA 452

Query: 1157 RTLYILASNSKDLSNSSINSIKVNTSLVDELLGCLLNCEPGLSCELVNHYISPFSTCPSH 978
            RTLYILAS+ KDLS S++++I VN SLV+ LLGCLLNC+PGLSC+LV  YI+P + CPS+
Sbjct: 453  RTLYILASDDKDLSTSALSAINVNASLVEALLGCLLNCDPGLSCDLVKKYIAPRTNCPSN 512

Query: 977  YVGVIQGEPSSEPYLGYVGDVSRFIWNYMADKTSIPSKN-VSPCSENCSKTGGICIKQEI 801
            YVGV+ GEPS+  Y GYV DVSRFIWN++AD+TSIP +N  S C ++CS  G +CI +E+
Sbjct: 513  YVGVLLGEPSATLYPGYVSDVSRFIWNFLADRTSIPRENATSACPKDCSNEGEVCIGEEL 572

Query: 800  DGKGECVMSTTRYIPAYSTRLKYDSSGTWSVLPPNSSDQMGVTDPIWTESNWNIISLRVY 621
            DGKG CV+STTRY+PAYSTRL ++ SG W V+P NSS+ MG  DP+WTESNW+ I LRVY
Sbjct: 573  DGKGVCVISTTRYVPAYSTRLMFE-SGIWKVMPLNSSNSMGTEDPVWTESNWDAIGLRVY 631

Query: 620  SVQGASYDHLVLMAGVAVTALSYLIIVVIKTFIAKALKQD 501
            +VQ A+YD LVL+AG+ VT L+YL IVV + FI KALKQD
Sbjct: 632  TVQNAAYDRLVLLAGLVVTVLAYLAIVVARAFITKALKQD 671


>gb|EOY19115.1| Zn-dependent exopeptidases superfamily protein isoform 1 [Theobroma
            cacao]
          Length = 666

 Score =  843 bits (2177), Expect = 0.0
 Identities = 413/639 (64%), Positives = 497/639 (77%)
 Frame = -1

Query: 2417 VPDLEKSMYTVLDGYPCVRLLNLSGEIGCANPSLDKVVAPIVRFKKGMELIRSSSVLVPL 2238
            VPDL+KSMY V+DGYPCVRL+NLSGEIGC+NP  DKVVAPIV++K   EL + S++L+ +
Sbjct: 30   VPDLQKSMYMVVDGYPCVRLVNLSGEIGCSNPGRDKVVAPIVKYKDTKELGQPSAILLSM 89

Query: 2237 PXXXXXXXXXXXXXXFARNVAGILVESGARNQTHLKGSSPDTKFPQAEFAPYQNNKFEWN 2058
                           FARNV G+LVESG   Q  LKG SP  KFPQAEFAPY N  +EWN
Sbjct: 90   DDVQGFFSRVSNDSSFARNVGGVLVESGIEIQNKLKGFSPAQKFPQAEFAPYHNTSYEWN 149

Query: 2057 PAGSGIMWKPYDFPVFLLSESSTETLQEIAVKNEDKKETYATKVTEFDLVMQTTKAGTHD 1878
            P G+G MWK Y+FPVFLLSESST TLQE+ +KNE  ++ Y T V EFDLVMQTTK GTHD
Sbjct: 150  PIGNGDMWKSYNFPVFLLSESSTSTLQEVTMKNEKTEKAYTTNVAEFDLVMQTTKVGTHD 209

Query: 1877 SESCLNEGTCLPLGGYSVWSALPTTNVSASSKEKPIVLAVASMDSASFFRDKSLGADSPL 1698
            SESCL E TCLPLGGYSVWSA+P  N S+S++ KPI++ VASMD+ASFFRDKSLGADSP+
Sbjct: 210  SESCLKEETCLPLGGYSVWSAVPPINSSSSNQSKPIIITVASMDAASFFRDKSLGADSPI 269

Query: 1697 SGLISLLAAVDALSRIEGSETLAKQIVFVVFTGEAWGYLGSRRFLFELDQHTDAVNGINN 1518
            SG+ISLLAAVDALSR++G + L KQ+VF+VFTGEAWGYLGSRRFL ELDQ +DAV G+N+
Sbjct: 270  SGVISLLAAVDALSRVDGLDDLNKQLVFLVFTGEAWGYLGSRRFLLELDQQSDAVRGLNS 329

Query: 1517 TLIETVIEVGSVGKGYDKGVKTFYAHTTGVSSATNETLKALQQAQDSLGTESIKYSAASK 1338
            TL+E V+E+GS GKG+ +G KTF+AHT  VSS  NE L AL+ AQ+SL +E +  S A+ 
Sbjct: 330  TLVELVMEIGSTGKGFSQGNKTFFAHTE-VSSGANEALDALKLAQESLKSEGVTISTANS 388

Query: 1337 SNPGIPPSSFMSFSKQKPHIAGVVLEDFDTSFTNKFYHSHLDDXXXXXXXXXXXXXXXXA 1158
            SNPGIPPSS M+F ++    +G+VLEDFD+ F NKFYHSHLDD                A
Sbjct: 389  SNPGIPPSSLMAFLRKNSSTSGIVLEDFDSIFVNKFYHSHLDDSSNINSSAIVAAASLVA 448

Query: 1157 RTLYILASNSKDLSNSSINSIKVNTSLVDELLGCLLNCEPGLSCELVNHYISPFSTCPSH 978
            RTLYILASN+KDL++S+I++I VN SLV+EL+ C+L+C PGLSCELV  YIS  +TCPSH
Sbjct: 449  RTLYILASNNKDLTSSAISTISVNASLVEELISCMLDCNPGLSCELVKSYISSTNTCPSH 508

Query: 977  YVGVIQGEPSSEPYLGYVGDVSRFIWNYMADKTSIPSKNVSPCSENCSKTGGICIKQEID 798
            YVGV+ GEPSS PY   V DVSRF+WN++AD+TSIP  N S CS +C K GG+CI+ E D
Sbjct: 509  YVGVVLGEPSSTPYPSQVDDVSRFLWNFLADRTSIPKGNTSVCSHDCGKNGGMCIRAETD 568

Query: 797  GKGECVMSTTRYIPAYSTRLKYDSSGTWSVLPPNSSDQMGVTDPIWTESNWNIISLRVYS 618
            GKG CV+STTRY+PAYSTRLK+D SGTW VLPPNS+D MG+ DP+WTESNWN I LRVY+
Sbjct: 569  GKGVCVISTTRYVPAYSTRLKFD-SGTWKVLPPNSTDPMGMLDPVWTESNWNTIGLRVYT 627

Query: 617  VQGASYDHLVLMAGVAVTALSYLIIVVIKTFIAKALKQD 501
            VQ  +YD LVL+ GVAVT LSY  IV+ + +I KALKQD
Sbjct: 628  VQDPAYDRLVLLGGVAVTVLSYFAIVLTRAYITKALKQD 666


>ref|XP_018816638.1| PREDICTED: nicastrin isoform X2 [Juglans regia]
          Length = 641

 Score =  842 bits (2174), Expect = 0.0
 Identities = 413/639 (64%), Positives = 500/639 (78%)
 Frame = -1

Query: 2417 VPDLEKSMYTVLDGYPCVRLLNLSGEIGCANPSLDKVVAPIVRFKKGMELIRSSSVLVPL 2238
            VPDL+KSMY  +DGYPCVRLLNLSG IGC+NP  + VVAPIVR+K  + L +SS+VLV  
Sbjct: 4    VPDLQKSMYKFIDGYPCVRLLNLSGVIGCSNPGREMVVAPIVRYKNTIALSQSSAVLVSS 63

Query: 2237 PXXXXXXXXXXXXXXFARNVAGILVESGARNQTHLKGSSPDTKFPQAEFAPYQNNKFEWN 2058
                           FA N+AG++VES    Q   KG SP  KFP AEFAPYQN  +EWN
Sbjct: 64   DELQSFLSRIWHDSSFAGNIAGVIVESENEFQNKSKGFSPAGKFPLAEFAPYQNTSYEWN 123

Query: 2057 PAGSGIMWKPYDFPVFLLSESSTETLQEIAVKNEDKKETYATKVTEFDLVMQTTKAGTHD 1878
            P GSGIMW  YDFPVFLLSESST TLQE A KNE  K+ Y   V EF+LVMQTTKAGTHD
Sbjct: 124  PIGSGIMWNAYDFPVFLLSESSTLTLQEAANKNEKNKKAYIADVAEFNLVMQTTKAGTHD 183

Query: 1877 SESCLNEGTCLPLGGYSVWSALPTTNVSASSKEKPIVLAVASMDSASFFRDKSLGADSPL 1698
            SE+CL E TCLPLGGYSVWS+LP  NVS+S + KPI+L +ASMDSASFFRDKSLGADSPL
Sbjct: 184  SETCLKEETCLPLGGYSVWSSLPPINVSSSDQSKPIILTMASMDSASFFRDKSLGADSPL 243

Query: 1697 SGLISLLAAVDALSRIEGSETLAKQIVFVVFTGEAWGYLGSRRFLFELDQHTDAVNGINN 1518
            SGLISLLAA+DALS ++G + L KQ+VF+ FTGE+WGYLGSRRFL+ELD  +DAV+G+NN
Sbjct: 244  SGLISLLAAIDALSHVDGLDDLTKQLVFIFFTGESWGYLGSRRFLYELDLQSDAVSGLNN 303

Query: 1517 TLIETVIEVGSVGKGYDKGVKTFYAHTTGVSSATNETLKALQQAQDSLGTESIKYSAASK 1338
            +LIE  IE+GSVGKG+++GVK FY HT  VSSATNETLKAL+ AQDS+ +E I  S A+ 
Sbjct: 304  SLIEMAIEIGSVGKGFNQGVKRFYTHTAEVSSATNETLKALKHAQDSMKSEHIIVSPANA 363

Query: 1337 SNPGIPPSSFMSFSKQKPHIAGVVLEDFDTSFTNKFYHSHLDDXXXXXXXXXXXXXXXXA 1158
            SNPGIPPSS M+F ++    +G+VLEDFD+ F+NKFYHSHLD+                A
Sbjct: 364  SNPGIPPSSLMAFLRKNSLSSGLVLEDFDSVFSNKFYHSHLDNISNINSSAIVAAASLVA 423

Query: 1157 RTLYILASNSKDLSNSSINSIKVNTSLVDELLGCLLNCEPGLSCELVNHYISPFSTCPSH 978
            RTLYILAS++K++S S++ +I VN SLV+EL+GCLL+C+PGLSCELV  YISP STCPSH
Sbjct: 424  RTLYILASDNKNVSGSALTAISVNVSLVEELMGCLLDCDPGLSCELVKDYISPTSTCPSH 483

Query: 977  YVGVIQGEPSSEPYLGYVGDVSRFIWNYMADKTSIPSKNVSPCSENCSKTGGICIKQEID 798
            Y GVI  EPSS PY GYV D+SRF+WN++AD+TSIPS+N S CS+ C   G +C+++E D
Sbjct: 484  YAGVILDEPSSTPYPGYVDDMSRFLWNFLADRTSIPSENGSSCSQGCHNKGAVCVREETD 543

Query: 797  GKGECVMSTTRYIPAYSTRLKYDSSGTWSVLPPNSSDQMGVTDPIWTESNWNIISLRVYS 618
            GKG CV+STTRY+PAYSTRLK++ SGTW+VLPPNSSD MG+ DP+WTESNWN I LRVY+
Sbjct: 544  GKGVCVISTTRYVPAYSTRLKFE-SGTWTVLPPNSSDPMGILDPVWTESNWNAIGLRVYT 602

Query: 617  VQGASYDHLVLMAGVAVTALSYLIIVVIKTFIAKALKQD 501
            VQ A+YDH+VL+AG++VT L+YL IV  +  + KALK+D
Sbjct: 603  VQDAAYDHIVLVAGISVTVLAYLAIVTTRAVLTKALKRD 641


>ref|XP_018816637.1| PREDICTED: nicastrin isoform X1 [Juglans regia]
          Length = 667

 Score =  842 bits (2174), Expect = 0.0
 Identities = 413/639 (64%), Positives = 500/639 (78%)
 Frame = -1

Query: 2417 VPDLEKSMYTVLDGYPCVRLLNLSGEIGCANPSLDKVVAPIVRFKKGMELIRSSSVLVPL 2238
            VPDL+KSMY  +DGYPCVRLLNLSG IGC+NP  + VVAPIVR+K  + L +SS+VLV  
Sbjct: 30   VPDLQKSMYKFIDGYPCVRLLNLSGVIGCSNPGREMVVAPIVRYKNTIALSQSSAVLVSS 89

Query: 2237 PXXXXXXXXXXXXXXFARNVAGILVESGARNQTHLKGSSPDTKFPQAEFAPYQNNKFEWN 2058
                           FA N+AG++VES    Q   KG SP  KFP AEFAPYQN  +EWN
Sbjct: 90   DELQSFLSRIWHDSSFAGNIAGVIVESENEFQNKSKGFSPAGKFPLAEFAPYQNTSYEWN 149

Query: 2057 PAGSGIMWKPYDFPVFLLSESSTETLQEIAVKNEDKKETYATKVTEFDLVMQTTKAGTHD 1878
            P GSGIMW  YDFPVFLLSESST TLQE A KNE  K+ Y   V EF+LVMQTTKAGTHD
Sbjct: 150  PIGSGIMWNAYDFPVFLLSESSTLTLQEAANKNEKNKKAYIADVAEFNLVMQTTKAGTHD 209

Query: 1877 SESCLNEGTCLPLGGYSVWSALPTTNVSASSKEKPIVLAVASMDSASFFRDKSLGADSPL 1698
            SE+CL E TCLPLGGYSVWS+LP  NVS+S + KPI+L +ASMDSASFFRDKSLGADSPL
Sbjct: 210  SETCLKEETCLPLGGYSVWSSLPPINVSSSDQSKPIILTMASMDSASFFRDKSLGADSPL 269

Query: 1697 SGLISLLAAVDALSRIEGSETLAKQIVFVVFTGEAWGYLGSRRFLFELDQHTDAVNGINN 1518
            SGLISLLAA+DALS ++G + L KQ+VF+ FTGE+WGYLGSRRFL+ELD  +DAV+G+NN
Sbjct: 270  SGLISLLAAIDALSHVDGLDDLTKQLVFIFFTGESWGYLGSRRFLYELDLQSDAVSGLNN 329

Query: 1517 TLIETVIEVGSVGKGYDKGVKTFYAHTTGVSSATNETLKALQQAQDSLGTESIKYSAASK 1338
            +LIE  IE+GSVGKG+++GVK FY HT  VSSATNETLKAL+ AQDS+ +E I  S A+ 
Sbjct: 330  SLIEMAIEIGSVGKGFNQGVKRFYTHTAEVSSATNETLKALKHAQDSMKSEHIIVSPANA 389

Query: 1337 SNPGIPPSSFMSFSKQKPHIAGVVLEDFDTSFTNKFYHSHLDDXXXXXXXXXXXXXXXXA 1158
            SNPGIPPSS M+F ++    +G+VLEDFD+ F+NKFYHSHLD+                A
Sbjct: 390  SNPGIPPSSLMAFLRKNSLSSGLVLEDFDSVFSNKFYHSHLDNISNINSSAIVAAASLVA 449

Query: 1157 RTLYILASNSKDLSNSSINSIKVNTSLVDELLGCLLNCEPGLSCELVNHYISPFSTCPSH 978
            RTLYILAS++K++S S++ +I VN SLV+EL+GCLL+C+PGLSCELV  YISP STCPSH
Sbjct: 450  RTLYILASDNKNVSGSALTAISVNVSLVEELMGCLLDCDPGLSCELVKDYISPTSTCPSH 509

Query: 977  YVGVIQGEPSSEPYLGYVGDVSRFIWNYMADKTSIPSKNVSPCSENCSKTGGICIKQEID 798
            Y GVI  EPSS PY GYV D+SRF+WN++AD+TSIPS+N S CS+ C   G +C+++E D
Sbjct: 510  YAGVILDEPSSTPYPGYVDDMSRFLWNFLADRTSIPSENGSSCSQGCHNKGAVCVREETD 569

Query: 797  GKGECVMSTTRYIPAYSTRLKYDSSGTWSVLPPNSSDQMGVTDPIWTESNWNIISLRVYS 618
            GKG CV+STTRY+PAYSTRLK++ SGTW+VLPPNSSD MG+ DP+WTESNWN I LRVY+
Sbjct: 570  GKGVCVISTTRYVPAYSTRLKFE-SGTWTVLPPNSSDPMGILDPVWTESNWNAIGLRVYT 628

Query: 617  VQGASYDHLVLMAGVAVTALSYLIIVVIKTFIAKALKQD 501
            VQ A+YDH+VL+AG++VT L+YL IV  +  + KALK+D
Sbjct: 629  VQDAAYDHIVLVAGISVTVLAYLAIVTTRAVLTKALKRD 667


>dbj|GAV60467.1| Nicastrin domain-containing protein [Cephalotus follicularis]
          Length = 668

 Score =  839 bits (2167), Expect = 0.0
 Identities = 415/640 (64%), Positives = 504/640 (78%), Gaps = 1/640 (0%)
 Frame = -1

Query: 2417 VPDLEKSMYTVLDGYPCVRLLNLSGEIGCANPSLDKVVAPIVRFKKGMELIRSSSVLVPL 2238
            VPDL+ SMY V+DGYPCVR LNLSG+IGC+NP  DKVVAPIVRFK   EL + S+VLV L
Sbjct: 30   VPDLQNSMYMVVDGYPCVRRLNLSGKIGCSNPWRDKVVAPIVRFKNANELHQPSAVLVSL 89

Query: 2237 PXXXXXXXXXXXXXXFARNVAGILVESGARNQTHLKGSSPDTKFPQAEFAPYQNNKFEWN 2058
                           F+ N+ G+LVESG   Q  LKG SP  KFPQA +APYQ+  +EWN
Sbjct: 90   DEIQDFFTRVGNDSSFSSNIGGVLVESGTEIQNKLKGFSPTQKFPQAVYAPYQSINYEWN 149

Query: 2057 PAGSGIMWKPYDFPVFLLSESSTETLQEIAVKNEDKKETYATKVTEFDLVMQTTKAGTHD 1878
            P GSGIMWK YDFPVFLLSE+ST TLQE+A +NE  K+    +V EF+LVMQTTKA THD
Sbjct: 150  PMGSGIMWKAYDFPVFLLSENSTLTLQEVAERNEKTKKDNTAEVAEFNLVMQTTKAATHD 209

Query: 1877 SESCLNEGTCLPLGGYSVWSALPTTNVSASSKEKPIVLAVASMDSASFFRDKSLGADSPL 1698
            SESCL E TCLPLGGYSVWS+LP  NV++ ++ KP++L +ASMDSASFF DK++GADSP+
Sbjct: 210  SESCLKEETCLPLGGYSVWSSLPPINVTSLNQSKPLILTLASMDSASFFHDKNIGADSPI 269

Query: 1697 SGLISLLAAVDALSRIEGSETLAKQIVFVVFTGEAWGYLGSRRFLFELDQHTDAVNGINN 1518
            SGLI+LLAAVD LS+++  + L+KQ+VF+VFTGEAWGYLGSRRFL ELD H+DAVNG+N+
Sbjct: 270  SGLIALLAAVDTLSQLDDVDELSKQLVFLVFTGEAWGYLGSRRFLLELDLHSDAVNGLNS 329

Query: 1517 TLIETVIEVGSVGKGYDKGVKTFYAHTTGVSSATNETLKALQQAQDSLGTESIKYSAASK 1338
            TLIE V+E+GSVGK   +GVKTF+AHT GV+SATNETL AL  A+DSL +ESIK  +A+ 
Sbjct: 330  TLIEMVLEIGSVGKALHQGVKTFFAHTAGVTSATNETLDALIGARDSLNSESIKILSANP 389

Query: 1337 SNPGIPPSSFMSFSKQKPHIAGVVLEDFDTSFTNKFYHSHLDDXXXXXXXXXXXXXXXXA 1158
            SNPG+PPSS M+F ++    +G+VLEDFD+ FTNKFYHSHLDD                A
Sbjct: 390  SNPGVPPSSLMAFLRKNSLTSGIVLEDFDSVFTNKFYHSHLDDSSNINSSSIVAAASLVA 449

Query: 1157 RTLYILASNSKDLSNSSINSIKVNTSLVDELLGCLLNCEPGLSCELVNHYISPFSTCPSH 978
            RTLYILAS+SK+LS+S++ +IKVN SLV+EL+GCLLNCEPGLSCELV  YIS  +TCPSH
Sbjct: 450  RTLYILASDSKNLSSSALGAIKVNVSLVEELMGCLLNCEPGLSCELVKKYISATNTCPSH 509

Query: 977  YVGVIQGEPSSEPYLGYVGDVSRFIWNYMADKTSIPSKN-VSPCSENCSKTGGICIKQEI 801
            YVGV+ GEPSS PY GYV D+SRFIWN++ADKTS    N  S C+++CSK GG+CI  EI
Sbjct: 510  YVGVVLGEPSSTPYAGYVDDISRFIWNFLADKTSTSEVNRSSVCTQDCSKKGGVCIGAEI 569

Query: 800  DGKGECVMSTTRYIPAYSTRLKYDSSGTWSVLPPNSSDQMGVTDPIWTESNWNIISLRVY 621
            DGKG CV STTRY+PAYSTRLK++ SGTW+VLPPN+SD MG+ DP+WTESNW+ I LRVY
Sbjct: 570  DGKGVCVTSTTRYVPAYSTRLKFE-SGTWNVLPPNTSDPMGMLDPVWTESNWDAIGLRVY 628

Query: 620  SVQGASYDHLVLMAGVAVTALSYLIIVVIKTFIAKALKQD 501
            ++Q A+YD LVL+ G+AVT L+YL IV  +T I KALK+D
Sbjct: 629  TIQDAAYDRLVLIGGIAVTVLAYLAIVATRTVITKALKRD 668


>ref|XP_021891327.1| nicastrin [Carica papaya]
          Length = 672

 Score =  837 bits (2162), Expect = 0.0
 Identities = 409/640 (63%), Positives = 495/640 (77%), Gaps = 1/640 (0%)
 Frame = -1

Query: 2417 VPDLEKSMYTVLDGYPCVRLLNLSGEIGCANPSLDKVVAPIVRFKKGMELIRSSSVLVPL 2238
            VPDL K MY V DGYPCVRLLNLSGEIGC+NP  DKVVAPI+RFK   EL +SS++LV  
Sbjct: 34   VPDLRKLMYIVADGYPCVRLLNLSGEIGCSNPGRDKVVAPIIRFKDAKELAQSSTILVSE 93

Query: 2237 PXXXXXXXXXXXXXXFARNVAGILVESGARNQTHLKGSSPDTKFPQAEFAPYQNNKFEWN 2058
                           F  N+ G+L+ESG   Q  LKG SPD KFPQAEFAPYQ+N +EWN
Sbjct: 94   DEIQAFFSRMLNDSSFTENIGGVLLESGTGIQNKLKGFSPDRKFPQAEFAPYQSNGYEWN 153

Query: 2057 PAGSGIMWKPYDFPVFLLSESSTETLQEIAVKNEDKKETYATKVTEFDLVMQTTKAGTHD 1878
            P GSGIMW  Y+FP FLLSESST+T+ EIA K +  ++ Y   V EFD+ M+TTKAGT +
Sbjct: 154  PIGSGIMWNTYNFPAFLLSESSTDTVLEIASKKDKTRKAYTANVAEFDMAMETTKAGTQN 213

Query: 1877 SESCLNEGTCLPLGGYSVWSALPTTNVSASSKEKPIVLAVASMDSASFFRDKSLGADSPL 1698
            SESCL E TCLPLGGYSVWS+LP  N+S+S ++KPIVL + SMDSASFFRDK+LGADSP+
Sbjct: 214  SESCLKEMTCLPLGGYSVWSSLPPINISSSDQKKPIVLTMTSMDSASFFRDKNLGADSPI 273

Query: 1697 SGLISLLAAVDALSRIEGSETLAKQIVFVVFTGEAWGYLGSRRFLFELDQHTDAVNGINN 1518
            SGLISLLAAVDALS ++G E L KQ+VF+V TGE+WGYLGSRRFL ELD  T+AV G+N+
Sbjct: 274  SGLISLLAAVDALSHVDGLENLNKQLVFLVLTGESWGYLGSRRFLLELDLRTEAVRGLNS 333

Query: 1517 TLIETVIEVGSVGKGYDKGVKTFYAHTTGVSSATNETLKALQQAQDSLGTESIKYSAASK 1338
            TLIETV+E+GSVGKG  +G+KTFYAH  GVSS TNETL AL+QA DSL +ES+   +AS 
Sbjct: 334  TLIETVVEIGSVGKGLSQGIKTFYAHKAGVSSNTNETLDALKQAGDSLKSESVSIFSASN 393

Query: 1337 SNPGIPPSSFMSFSKQKPHIAGVVLEDFDTSFTNKFYHSHLDDXXXXXXXXXXXXXXXXA 1158
            SNPGIPPSS M+F ++ P   G+VLEDFD +FTNKFYHSHLDD                A
Sbjct: 394  SNPGIPPSSLMAFLRKNPFTPGIVLEDFDNNFTNKFYHSHLDDLSNINSSSVAAAAALVA 453

Query: 1157 RTLYILASNSKDLSNSSINSIKVNTSLVDELLGCLLNCEPGLSCELVNHYISPFSTCPSH 978
            RTLYILAS+SKD+S+S +++I VN +LV+EL+GCLL+C+PGLSCELV +YISP  TCPSH
Sbjct: 454  RTLYILASDSKDVSSSDLSAISVNITLVEELMGCLLDCDPGLSCELVKNYISPAGTCPSH 513

Query: 977  YVGVIQGEPSSEPYLGYVGDVSRFIWNYMADKTS-IPSKNVSPCSENCSKTGGICIKQEI 801
            YVGVI GEPS+ PY GYV D+SRF+WN++ADKTS +     S CS+ CS    +CIK E 
Sbjct: 514  YVGVILGEPSATPYPGYVSDISRFVWNFLADKTSKLEDNATSVCSQGCSNRSEVCIKAET 573

Query: 800  DGKGECVMSTTRYIPAYSTRLKYDSSGTWSVLPPNSSDQMGVTDPIWTESNWNIISLRVY 621
            DGKG CV STTRY+PAYSTRLK++ SGTW++LP NSSD MG+ DP+WTESNWN I LRVY
Sbjct: 574  DGKGVCVTSTTRYVPAYSTRLKFE-SGTWNLLPSNSSDTMGMLDPVWTESNWNTIGLRVY 632

Query: 620  SVQGASYDHLVLMAGVAVTALSYLIIVVIKTFIAKALKQD 501
            +VQ A+YD +VL+AG+A+T L+YL I+  ++ I KALK+D
Sbjct: 633  TVQDAAYDRIVLLAGIAITVLAYLAIISTRSLITKALKRD 672


>ref|XP_019223514.1| PREDICTED: nicastrin isoform X2 [Nicotiana attenuata]
          Length = 670

 Score =  835 bits (2157), Expect = 0.0
 Identities = 411/640 (64%), Positives = 498/640 (77%), Gaps = 1/640 (0%)
 Frame = -1

Query: 2417 VPDLEKSMYTVLDGYPCVRLLNLSGEIGCANPSLDKVVAPIVRFKKGMELIRSSSVLVPL 2238
            VPDLEKSMY  +DGYPCVRLLNLSGEIGC+NP    +VAP+ RFK   +L   S+++V +
Sbjct: 33   VPDLEKSMYMAIDGYPCVRLLNLSGEIGCSNPGRANIVAPVARFKTANKLAEPSALMVSI 92

Query: 2237 PXXXXXXXXXXXXXXFARNVAGILVESGARNQTHLKGSSPDTKFPQAEFAPYQNNKFEWN 2058
                           F+R+V G+LVESG++ Q  LKG SPD KFPQAEFAPYQ+  FEWN
Sbjct: 93   EQFEELFGRLSNDAEFSRHVVGVLVESGSQLQNGLKGFSPDKKFPQAEFAPYQSGHFEWN 152

Query: 2057 PAGSGIMWKPYDFPVFLLSESSTETLQEIAVKNEDKKETYATKVTEFDLVMQTTKAGTHD 1878
            P GSG+MWK Y+FPVFLLS SST  LQEIA++NE +K++Y   V +F+LVMQTTK+GT D
Sbjct: 153  PIGSGLMWKAYNFPVFLLSNSSTSALQEIALRNEKRKKSYTVDVADFNLVMQTTKSGTRD 212

Query: 1877 SESCLNEGTCLPLGGYSVWSALPTTNVSASSKEKPIVLAVASMDSASFFRDKSLGADSPL 1698
            SESCL E TCLPLGGYSVWSALP   +S+S K KP++L VASMD+ASFFRDKS+GADSP+
Sbjct: 213  SESCLREQTCLPLGGYSVWSALPPMAISSSEKAKPVILVVASMDAASFFRDKSIGADSPI 272

Query: 1697 SGLISLLAAVDALSRIEGSETLAKQIVFVVFTGEAWGYLGSRRFLFELDQHTDAVNGINN 1518
            SGLISLLA VDALSR++G + L KQ+VF VFTGEAWGYLGSRRFL ELDQH+DAV+G++ 
Sbjct: 273  SGLISLLAVVDALSRVDGLKDLDKQLVFAVFTGEAWGYLGSRRFLLELDQHSDAVSGLDL 332

Query: 1517 TLIETVIEVGSVGKGYDKGVKTFYAHTTGVSSATNETLKALQQAQDSLGTESIKYSAASK 1338
             LIETV+E+GSVGKG+ +  KTF+AH+T   +ATN TL A+Q A  SL T+S K S ASK
Sbjct: 333  ALIETVLEIGSVGKGFARDDKTFFAHSTS-ETATNGTLSAIQDAVGSLKTQSTKISRASK 391

Query: 1337 SNPGIPPSSFMSFSKQKPHIAGVVLEDFDTSFTNKFYHSHLDDXXXXXXXXXXXXXXXXA 1158
            SNPG+PPSS MSF K+ P  +GVVLEDFDT+FTNKFYHSHLDD                A
Sbjct: 392  SNPGLPPSSLMSFLKKNPKTSGVVLEDFDTAFTNKFYHSHLDDLLNINSSAIVAAASVVA 451

Query: 1157 RTLYILASNSKDLSNSSINSIKVNTSLVDELLGCLLNCEPGLSCELVNHYISPFSTCPSH 978
            R+LYILAS+ K++  S++N+I +N SLV+ELLGCLL+CEPGLSCELVN YI+P ++CPSH
Sbjct: 452  RSLYILASDKKEIKTSALNTININASLVEELLGCLLSCEPGLSCELVNRYIAPSTSCPSH 511

Query: 977  YVGVIQGEPSSEPYLGYVGDVSRFIWNYMADKTSIPSKNV-SPCSENCSKTGGICIKQEI 801
            YVGV+ GEPSS+PY G VGDV RF+WN++ADKT+IPSKN+ S C + CS  G +C+K E 
Sbjct: 512  YVGVVLGEPSSQPYPGNVGDVPRFVWNFLADKTAIPSKNLSSTCPKGCSGNGEMCVKAET 571

Query: 800  DGKGECVMSTTRYIPAYSTRLKYDSSGTWSVLPPNSSDQMGVTDPIWTESNWNIISLRVY 621
            DGKG CV+STTRYIPAYSTRLKY+S  TW VLP NSSD MG  DP+WTESNW  I LRVY
Sbjct: 572  DGKGVCVISTTRYIPAYSTRLKYESD-TWEVLPHNSSDIMGEADPVWTESNWETIKLRVY 630

Query: 620  SVQGASYDHLVLMAGVAVTALSYLIIVVIKTFIAKALKQD 501
            +VQ   +D  +L+ G+AVT LSY+I V+ K FI KALK+D
Sbjct: 631  TVQDTRFDTWILLLGIAVTVLSYIITVMAKAFITKALKRD 670


>ref|XP_009758540.1| PREDICTED: nicastrin isoform X2 [Nicotiana sylvestris]
 ref|XP_016500129.1| PREDICTED: nicastrin-like isoform X2 [Nicotiana tabacum]
          Length = 670

 Score =  835 bits (2157), Expect = 0.0
 Identities = 411/640 (64%), Positives = 498/640 (77%), Gaps = 1/640 (0%)
 Frame = -1

Query: 2417 VPDLEKSMYTVLDGYPCVRLLNLSGEIGCANPSLDKVVAPIVRFKKGMELIRSSSVLVPL 2238
            VPDLEKSMY  +DGYPCVRLLNLSGEIGC+NP    +VAP+ RFK   +L   S+++V +
Sbjct: 33   VPDLEKSMYMAIDGYPCVRLLNLSGEIGCSNPGRANIVAPVARFKTANKLAEPSALVVSI 92

Query: 2237 PXXXXXXXXXXXXXXFARNVAGILVESGARNQTHLKGSSPDTKFPQAEFAPYQNNKFEWN 2058
                           F+R+V G+LVESG++ Q  LKG SPD KFPQAEFAPY++  FEWN
Sbjct: 93   DQFEELFGRLSNDAEFSRHVVGVLVESGSQLQNGLKGFSPDKKFPQAEFAPYRSGSFEWN 152

Query: 2057 PAGSGIMWKPYDFPVFLLSESSTETLQEIAVKNEDKKETYATKVTEFDLVMQTTKAGTHD 1878
            P GSG+MWK Y+FPVFLLS SST  LQEIA++NE +K++Y   V +F+LVMQTTK+GT D
Sbjct: 153  PIGSGLMWKAYNFPVFLLSNSSTSALQEIALRNEKRKKSYTVDVADFNLVMQTTKSGTRD 212

Query: 1877 SESCLNEGTCLPLGGYSVWSALPTTNVSASSKEKPIVLAVASMDSASFFRDKSLGADSPL 1698
            SESCL E TCLPLGGYSVWSALP   +S+S K KP++L VASMD+ASFFRDKS+GADSP+
Sbjct: 213  SESCLREQTCLPLGGYSVWSALPPMAISSSEKAKPVILVVASMDAASFFRDKSIGADSPI 272

Query: 1697 SGLISLLAAVDALSRIEGSETLAKQIVFVVFTGEAWGYLGSRRFLFELDQHTDAVNGINN 1518
            SGLISLL  VDALSR++G + L KQ+VF VFTGEAWGYLGSRRFL ELDQH+DAV+G++ 
Sbjct: 273  SGLISLLTVVDALSRVDGLKDLDKQLVFAVFTGEAWGYLGSRRFLLELDQHSDAVSGLDL 332

Query: 1517 TLIETVIEVGSVGKGYDKGVKTFYAHTTGVSSATNETLKALQQAQDSLGTESIKYSAASK 1338
             LIETV+E+GSVGKG+ +  KTF+AH+T   +ATN TL A+Q A  SL T+SIK S ASK
Sbjct: 333  ALIETVLEIGSVGKGFAQDDKTFFAHSTS-ETATNGTLSAIQDALGSLRTQSIKISRASK 391

Query: 1337 SNPGIPPSSFMSFSKQKPHIAGVVLEDFDTSFTNKFYHSHLDDXXXXXXXXXXXXXXXXA 1158
            SNPG+PPSS MSF K+ P  +GVVLEDFDT+FTNKFYHSHLDD                A
Sbjct: 392  SNPGLPPSSLMSFLKKNPKTSGVVLEDFDTAFTNKFYHSHLDDLLNINSSAIVAAASVVA 451

Query: 1157 RTLYILASNSKDLSNSSINSIKVNTSLVDELLGCLLNCEPGLSCELVNHYISPFSTCPSH 978
            R+LYILASN K++  S++N+I +N SLV+ELLGCLL+CEPGLSCELVN YI+P ++CPSH
Sbjct: 452  RSLYILASNKKEIKTSALNTININASLVEELLGCLLSCEPGLSCELVNRYIAPSTSCPSH 511

Query: 977  YVGVIQGEPSSEPYLGYVGDVSRFIWNYMADKTSIPSKNV-SPCSENCSKTGGICIKQEI 801
            YVGV+ GEPSS+PY G VGDV RF+WN++ADKT+IPSKN+ S C + CS  G +C+K E 
Sbjct: 512  YVGVVLGEPSSQPYPGNVGDVPRFVWNFLADKTAIPSKNLSSTCPKGCSGKGEMCVKAET 571

Query: 800  DGKGECVMSTTRYIPAYSTRLKYDSSGTWSVLPPNSSDQMGVTDPIWTESNWNIISLRVY 621
            DGKG CV+STTRYIPAYSTRLKY+S  TW VLP NSSD MG  DP+WTESNW  I LRVY
Sbjct: 572  DGKGVCVISTTRYIPAYSTRLKYESD-TWEVLPHNSSDIMGEADPVWTESNWETIKLRVY 630

Query: 620  SVQGASYDHLVLMAGVAVTALSYLIIVVIKTFIAKALKQD 501
            +VQ   +D  +L+ G+AVT LSY+I V+ K FI KALK+D
Sbjct: 631  TVQDTRFDTWILLLGIAVTVLSYIITVMAKAFITKALKRD 670


>gb|KDP25818.1| hypothetical protein JCGZ_22540 [Jatropha curcas]
          Length = 671

 Score =  835 bits (2157), Expect = 0.0
 Identities = 404/640 (63%), Positives = 497/640 (77%), Gaps = 1/640 (0%)
 Frame = -1

Query: 2417 VPDLEKSMYTVLDGYPCVRLLNLSGEIGCANPSLDKVVAPIVRFKKGMELIRSSSVLVPL 2238
            VPDL+KSMY V+DGYPCVRLLNLSGEIGCANP  DKVVAP++RFK   EL  SS+VLV L
Sbjct: 33   VPDLQKSMYKVIDGYPCVRLLNLSGEIGCANPGRDKVVAPVIRFKNARELAHSSAVLVSL 92

Query: 2237 PXXXXXXXXXXXXXXFARNVAGILVESGARNQTHLKGSSPDTKFPQAEFAPYQNNKFEWN 2058
                           FA+N+ G+LVE   +NQ+   G SP  KFP+ +FAPY++  +EWN
Sbjct: 93   DEIQELFDRISNDSSFAKNIGGVLVEPRTKNQSQSTGFSPAQKFPEVQFAPYKSVNYEWN 152

Query: 2057 PAGSGIMWKPYDFPVFLLSESSTETLQEIAVKNEDKKETYATKVTEFDLVMQTTKAGTHD 1878
            P GSGIMWK Y+FPVFLLSE S++ +QE+A+KN ++K  Y   V EFD VMQTTK+GTHD
Sbjct: 153  PIGSGIMWKAYNFPVFLLSEESSQFMQEVALKNANQKNAYTAYVAEFDSVMQTTKSGTHD 212

Query: 1877 SESCLNEGTCLPLGGYSVWSALPTTNVSASSKEKPIVLAVASMDSASFFRDKSLGADSPL 1698
            SESCL EGTCLPLGGYSVWS+LP  NVS+S++ KPI+LA +SMDSASFFRDKSLGA+SP+
Sbjct: 213  SESCLREGTCLPLGGYSVWSSLPPINVSSSNQSKPIILAASSMDSASFFRDKSLGAESPI 272

Query: 1697 SGLISLLAAVDALSRIEGSETLAKQIVFVVFTGEAWGYLGSRRFLFELDQHTDAVNGINN 1518
            SGLISLLAAVD+LS ++G   L+KQ+VF VFTGEAWGYLGSRRFL ELD  +DAV+G+N+
Sbjct: 273  SGLISLLAAVDSLSHVDGLSDLSKQLVFSVFTGEAWGYLGSRRFLLELDLRSDAVSGLND 332

Query: 1517 TLIETVIEVGSVGKGYDKGVKTFYAHTTGVSSATNETLKALQQAQDSLGTESIKYSAASK 1338
             L+ETVIE+GSVGKG+  G  TF+ H  GVSSATNETLKA + AQDSL ++++    AS 
Sbjct: 333  KLVETVIEIGSVGKGFSGGNNTFFIHRAGVSSATNETLKAFKHAQDSLESKNVTIVEAST 392

Query: 1337 SNPGIPPSSFMSFSKQKPHIAGVVLEDFDTSFTNKFYHSHLDDXXXXXXXXXXXXXXXXA 1158
            SNPGIPPSS M+F ++     G+VLEDFDT+F NKFYHSHLDD                A
Sbjct: 393  SNPGIPPSSLMAFLRKNSSTNGIVLEDFDTAFANKFYHSHLDDMSNVNSSAIVAAASLIA 452

Query: 1157 RTLYILASNSKDLSNSSINSIKVNTSLVDELLGCLLNCEPGLSCELVNHYISPFSTCPSH 978
            RTLYILAS + +LS+S++N+I VN SLV+EL+ CLL C PGLSC+LV +Y+SP S+CP+H
Sbjct: 453  RTLYILASGNNNLSSSALNAINVNASLVEELMSCLLGCNPGLSCDLVKNYMSPTSSCPNH 512

Query: 977  YVGVIQGEPSSEPYLGYVGDVSRFIWNYMADKTSIPSKNV-SPCSENCSKTGGICIKQEI 801
            YVGVI GEPSS PYLGYV D+SRFIWN++AD+TS P +N  S CS+ CS    +CI+ E 
Sbjct: 513  YVGVIIGEPSSTPYLGYVDDISRFIWNFLADRTSTPKENTKSDCSKGCSNKDEVCIRAET 572

Query: 800  DGKGECVMSTTRYIPAYSTRLKYDSSGTWSVLPPNSSDQMGVTDPIWTESNWNIISLRVY 621
            +GKG CV STTRY+PAYSTRLKY+ SG W+VLP NSSD MG+ DP+WTESNW++I LR Y
Sbjct: 573  NGKGVCVTSTTRYVPAYSTRLKYE-SGMWTVLPANSSDPMGMVDPVWTESNWDVIGLRAY 631

Query: 620  SVQGASYDHLVLMAGVAVTALSYLIIVVIKTFIAKALKQD 501
            ++Q ASYD LVL+ G+AVT L+Y++IV+ + FI K LKQD
Sbjct: 632  TIQNASYDRLVLLGGIAVTILAYVVIVITRAFITKVLKQD 671


>ref|XP_012086441.1| nicastrin [Jatropha curcas]
          Length = 678

 Score =  835 bits (2157), Expect = 0.0
 Identities = 404/640 (63%), Positives = 497/640 (77%), Gaps = 1/640 (0%)
 Frame = -1

Query: 2417 VPDLEKSMYTVLDGYPCVRLLNLSGEIGCANPSLDKVVAPIVRFKKGMELIRSSSVLVPL 2238
            VPDL+KSMY V+DGYPCVRLLNLSGEIGCANP  DKVVAP++RFK   EL  SS+VLV L
Sbjct: 40   VPDLQKSMYKVIDGYPCVRLLNLSGEIGCANPGRDKVVAPVIRFKNARELAHSSAVLVSL 99

Query: 2237 PXXXXXXXXXXXXXXFARNVAGILVESGARNQTHLKGSSPDTKFPQAEFAPYQNNKFEWN 2058
                           FA+N+ G+LVE   +NQ+   G SP  KFP+ +FAPY++  +EWN
Sbjct: 100  DEIQELFDRISNDSSFAKNIGGVLVEPRTKNQSQSTGFSPAQKFPEVQFAPYKSVNYEWN 159

Query: 2057 PAGSGIMWKPYDFPVFLLSESSTETLQEIAVKNEDKKETYATKVTEFDLVMQTTKAGTHD 1878
            P GSGIMWK Y+FPVFLLSE S++ +QE+A+KN ++K  Y   V EFD VMQTTK+GTHD
Sbjct: 160  PIGSGIMWKAYNFPVFLLSEESSQFMQEVALKNANQKNAYTAYVAEFDSVMQTTKSGTHD 219

Query: 1877 SESCLNEGTCLPLGGYSVWSALPTTNVSASSKEKPIVLAVASMDSASFFRDKSLGADSPL 1698
            SESCL EGTCLPLGGYSVWS+LP  NVS+S++ KPI+LA +SMDSASFFRDKSLGA+SP+
Sbjct: 220  SESCLREGTCLPLGGYSVWSSLPPINVSSSNQSKPIILAASSMDSASFFRDKSLGAESPI 279

Query: 1697 SGLISLLAAVDALSRIEGSETLAKQIVFVVFTGEAWGYLGSRRFLFELDQHTDAVNGINN 1518
            SGLISLLAAVD+LS ++G   L+KQ+VF VFTGEAWGYLGSRRFL ELD  +DAV+G+N+
Sbjct: 280  SGLISLLAAVDSLSHVDGLSDLSKQLVFSVFTGEAWGYLGSRRFLLELDLRSDAVSGLND 339

Query: 1517 TLIETVIEVGSVGKGYDKGVKTFYAHTTGVSSATNETLKALQQAQDSLGTESIKYSAASK 1338
             L+ETVIE+GSVGKG+  G  TF+ H  GVSSATNETLKA + AQDSL ++++    AS 
Sbjct: 340  KLVETVIEIGSVGKGFSGGNNTFFIHRAGVSSATNETLKAFKHAQDSLESKNVTIVEAST 399

Query: 1337 SNPGIPPSSFMSFSKQKPHIAGVVLEDFDTSFTNKFYHSHLDDXXXXXXXXXXXXXXXXA 1158
            SNPGIPPSS M+F ++     G+VLEDFDT+F NKFYHSHLDD                A
Sbjct: 400  SNPGIPPSSLMAFLRKNSSTNGIVLEDFDTAFANKFYHSHLDDMSNVNSSAIVAAASLIA 459

Query: 1157 RTLYILASNSKDLSNSSINSIKVNTSLVDELLGCLLNCEPGLSCELVNHYISPFSTCPSH 978
            RTLYILAS + +LS+S++N+I VN SLV+EL+ CLL C PGLSC+LV +Y+SP S+CP+H
Sbjct: 460  RTLYILASGNNNLSSSALNAINVNASLVEELMSCLLGCNPGLSCDLVKNYMSPTSSCPNH 519

Query: 977  YVGVIQGEPSSEPYLGYVGDVSRFIWNYMADKTSIPSKNV-SPCSENCSKTGGICIKQEI 801
            YVGVI GEPSS PYLGYV D+SRFIWN++AD+TS P +N  S CS+ CS    +CI+ E 
Sbjct: 520  YVGVIIGEPSSTPYLGYVDDISRFIWNFLADRTSTPKENTKSDCSKGCSNKDEVCIRAET 579

Query: 800  DGKGECVMSTTRYIPAYSTRLKYDSSGTWSVLPPNSSDQMGVTDPIWTESNWNIISLRVY 621
            +GKG CV STTRY+PAYSTRLKY+ SG W+VLP NSSD MG+ DP+WTESNW++I LR Y
Sbjct: 580  NGKGVCVTSTTRYVPAYSTRLKYE-SGMWTVLPANSSDPMGMVDPVWTESNWDVIGLRAY 638

Query: 620  SVQGASYDHLVLMAGVAVTALSYLIIVVIKTFIAKALKQD 501
            ++Q ASYD LVL+ G+AVT L+Y++IV+ + FI K LKQD
Sbjct: 639  TIQNASYDRLVLLGGIAVTILAYVVIVITRAFITKVLKQD 678


>ref|XP_017248165.1| PREDICTED: nicastrin [Daucus carota subsp. sativus]
          Length = 667

 Score =  834 bits (2154), Expect = 0.0
 Identities = 411/640 (64%), Positives = 508/640 (79%), Gaps = 1/640 (0%)
 Frame = -1

Query: 2417 VPDLEKSMYTVLDGYPCVRLLNLSGEIGCANPSLDKVVAPIVRFKKGMELIRSSSVLVPL 2238
            VPDLEKSMY+++DG+PCVRLLNL GEIGC+NP   KVVAP+VR      +++ S++LV  
Sbjct: 31   VPDLEKSMYSIIDGFPCVRLLNLHGEIGCSNPGNGKVVAPVVRLDSAENIVQPSALLVSS 90

Query: 2237 PXXXXXXXXXXXXXXFARNVAGILVESGARNQTHLKGSSPDTKFPQAEFAPYQNNKFEWN 2058
                           FARNVAG+LV+S  +++  LKG SPDTKFPQAEF+PY +   +WN
Sbjct: 91   DEYDSLLKRISDDSHFARNVAGVLVQSDMQDK--LKGLSPDTKFPQAEFSPYDSRTHQWN 148

Query: 2057 PAGSGIMWKPYDFPVFLLSESSTETLQEIAVKNEDKKETYATKVTEFDLVMQTTKAGTHD 1878
            P GSG MW  Y+FPVFLLS+SST  LQE+A KNE + +  AT V EFD+VMQTTKAGTH+
Sbjct: 149  PNGSGTMWGRYNFPVFLLSQSSTAKLQEVAEKNEKRNKGSATHVAEFDVVMQTTKAGTHN 208

Query: 1877 SESCLNEGTCLPLGGYSVWSALPTTNVSASSKEKPIVLAVASMDSASFFRDKSLGADSPL 1698
            SESCL E  CLPLGGYSVWSALP  + + S++ KPI+LAV SMD+ASFFRDKSLGADSP+
Sbjct: 209  SESCLEEEACLPLGGYSVWSALPPIDTTLSTQSKPIILAVTSMDAASFFRDKSLGADSPI 268

Query: 1697 SGLISLLAAVDALSRIEGSETLAKQIVFVVFTGEAWGYLGSRRFLFELDQHTDAVNGINN 1518
            SGLISLLAAVDALSR++G + LAKQ+VFVVFTGEAWGYLGSRRFL ELDQH+DA +G+++
Sbjct: 269  SGLISLLAAVDALSRVDGLKDLAKQLVFVVFTGEAWGYLGSRRFLAELDQHSDATSGLSH 328

Query: 1517 TLIETVIEVGSVGKGYDKGVKTFYAHTTGVSSATNETLKALQQAQDSLGTESIKYSAASK 1338
             LIETV+EVGSVGKG+D GVK+F+AH TGVSS TN+TLKAL++AQ+SLGTESIK S+AS 
Sbjct: 329  MLIETVLEVGSVGKGFDDGVKSFFAHATGVSSGTNDTLKALKKAQESLGTESIKISSASS 388

Query: 1337 SNPGIPPSSFMSFSKQKPHIAGVVLEDFDTSFTNKFYHSHLDDXXXXXXXXXXXXXXXXA 1158
            SNPGIPPSS M+F  +    +G+VLE+FDT F NK YHSHLDD                A
Sbjct: 389  SNPGIPPSSLMAFLNKDSRTSGIVLEEFDTVFDNKLYHSHLDDITNINSSAIIAAATIVA 448

Query: 1157 RTLYILASNSKDLSNSSINSIKVNTSLVDELLGCLLNCEPGLSCELVNHYISPFSTCPSH 978
            R+LYILAS++K+LS+S+++++ VNTSLV+ELLGCLL+CEPGLSC+LV  YISP S+CPSH
Sbjct: 449  RSLYILASDNKELSSSALSAVSVNTSLVEELLGCLLSCEPGLSCDLVKQYISPTSSCPSH 508

Query: 977  YVGVIQGEPSSEPYLGYVGDVSRFIWNYMADKTSIPSKN-VSPCSENCSKTGGICIKQEI 801
            YVGV+  EPSS PYLGYVGDV RF+WN++A+KTS PSKN  S C ++CS TG  CIK E 
Sbjct: 509  YVGVVLEEPSSTPYLGYVGDVPRFVWNFLAEKTSFPSKNDSSACPKDCSNTGESCIKAET 568

Query: 800  DGKGECVMSTTRYIPAYSTRLKYDSSGTWSVLPPNSSDQMGVTDPIWTESNWNIISLRVY 621
            DGKG CV+STTRY+PAYSTRLK++S  +W VLP N+SD MGV DP+W+ESNW  I LRV+
Sbjct: 569  DGKGVCVISTTRYVPAYSTRLKFESE-SWKVLPKNASDPMGVADPVWSESNWAPIQLRVF 627

Query: 620  SVQGASYDHLVLMAGVAVTALSYLIIVVIKTFIAKALKQD 501
             VQ +SYD+L+L  G+ +T LSY+ IVV ++ IAK++K+D
Sbjct: 628  LVQDSSYDYLILFVGIGLTVLSYIAIVVARSIIAKSMKRD 667


>ref|XP_006352434.1| PREDICTED: nicastrin isoform X2 [Solanum tuberosum]
          Length = 670

 Score =  833 bits (2152), Expect = 0.0
 Identities = 412/640 (64%), Positives = 495/640 (77%), Gaps = 1/640 (0%)
 Frame = -1

Query: 2417 VPDLEKSMYTVLDGYPCVRLLNLSGEIGCANPSLDKVVAPIVRFKKGMELIRSSSVLVPL 2238
            VPDLEKSMY  +DGYPCVRLLNLSGEIGC+NP    +VAP+ RFK   +L   S++LV +
Sbjct: 33   VPDLEKSMYMAIDGYPCVRLLNLSGEIGCSNPGRANIVAPVTRFKTENKLAEPSALLVSM 92

Query: 2237 PXXXXXXXXXXXXXXFARNVAGILVESGARNQTHLKGSSPDTKFPQAEFAPYQNNKFEWN 2058
                           F+R+V G+LVES ++ Q  LKG SPD KFPQAEF PYQ+ KFEWN
Sbjct: 93   DQFEDLFARLSIDADFSRHVVGVLVESSSQLQNGLKGFSPDKKFPQAEFTPYQSGKFEWN 152

Query: 2057 PAGSGIMWKPYDFPVFLLSESSTETLQEIAVKNEDKKETYATKVTEFDLVMQTTKAGTHD 1878
            P GSG+MWK Y+FPVFLLS SST  LQE+A++NE +K++    V +FDLVMQTTK+GT D
Sbjct: 153  PTGSGLMWKAYNFPVFLLSNSSTLALQEVALRNEKRKKSSTVDVADFDLVMQTTKSGTRD 212

Query: 1877 SESCLNEGTCLPLGGYSVWSALPTTNVSASSKEKPIVLAVASMDSASFFRDKSLGADSPL 1698
            SESCL E TCLPLGGYSVWSALP   VS+S K KP++L VASMD+AS FRD S+GADSP+
Sbjct: 213  SESCLREQTCLPLGGYSVWSALPPIIVSSSKKAKPVILTVASMDAASLFRDVSIGADSPI 272

Query: 1697 SGLISLLAAVDALSRIEGSETLAKQIVFVVFTGEAWGYLGSRRFLFELDQHTDAVNGINN 1518
            SGLISLLA VDALSR++G   L KQ+VF VFTGEAWGYLGSRRFL ELDQH+DAV+G++ 
Sbjct: 273  SGLISLLAVVDALSRVDGLGDLDKQLVFAVFTGEAWGYLGSRRFLLELDQHSDAVSGLDL 332

Query: 1517 TLIETVIEVGSVGKGYDKGVKTFYAHTTGVSSATNETLKALQQAQDSLGTESIKYSAASK 1338
             LIETV+E+GSVGKG+ +   TF+AH+T   SATN TL AL+ A  SL T+SIK S ASK
Sbjct: 333  ALIETVLEIGSVGKGFTQDDNTFFAHST-TESATNGTLSALKDALGSLKTQSIKISRASK 391

Query: 1337 SNPGIPPSSFMSFSKQKPHIAGVVLEDFDTSFTNKFYHSHLDDXXXXXXXXXXXXXXXXA 1158
            SNPG+PPSS MSF K+ P  +GVVLEDFD +FTNKFYHSHLDD                A
Sbjct: 392  SNPGLPPSSLMSFLKKNPETSGVVLEDFDAAFTNKFYHSHLDDLSNINSSAIVAAASIVA 451

Query: 1157 RTLYILASNSKDLSNSSINSIKVNTSLVDELLGCLLNCEPGLSCELVNHYISPFSTCPSH 978
            R+LYILAS+ K++ NS +N+I +N SLV+ELLGCLL+CEPG +CELVNHYI+P + CPSH
Sbjct: 452  RSLYILASDKKEIKNSVLNTININASLVEELLGCLLSCEPGYTCELVNHYIAPSTRCPSH 511

Query: 977  YVGVIQGEPSSEPYLGYVGDVSRFIWNYMADKTSIPSKNV-SPCSENCSKTGGICIKQEI 801
            YVGV+ GEPSS+PYLG VGDVSRF+WN++ADKT+IPSKN+ S C + CS  G +C+K E 
Sbjct: 512  YVGVVMGEPSSQPYLGNVGDVSRFVWNFLADKTAIPSKNMSSTCPKGCSGNGEMCVKAET 571

Query: 800  DGKGECVMSTTRYIPAYSTRLKYDSSGTWSVLPPNSSDQMGVTDPIWTESNWNIISLRVY 621
            DGKG CV+STTRY+PAYSTRLKY+S  TW VLP NSSD MG  DP+WTESNW+ I LRVY
Sbjct: 572  DGKGVCVISTTRYVPAYSTRLKYESE-TWEVLPHNSSDTMGEADPVWTESNWDTIRLRVY 630

Query: 620  SVQGASYDHLVLMAGVAVTALSYLIIVVIKTFIAKALKQD 501
            +VQ   +D LVL+ G+ VT LSY+IIV+ K FI KALK+D
Sbjct: 631  TVQDTGFDLLVLLLGITVTVLSYIIIVISKAFITKALKRD 670