BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Cheilocostus21_contig00004710
         (3267 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_009384014.1| PREDICTED: Niemann-Pick C1 protein-like [Mus...   970   0.0  
gb|KDO85101.1| hypothetical protein CISIN_1g000762mg [Citrus sin...   826   0.0  
gb|PIA46755.1| hypothetical protein AQUCO_01500358v1 [Aquilegia ...   807   0.0  
ref|XP_022762939.1| Niemann-Pick C1 protein isoform X4 [Durio zi...   782   0.0  
ref|XP_019705210.1| PREDICTED: Niemann-Pick C1 protein-like isof...   738   0.0  
ref|XP_009384608.1| PREDICTED: Niemann-Pick C1 protein-like isof...   901   0.0  
ref|XP_019702346.1| PREDICTED: Niemann-Pick C1 protein-like [Ela...   865   0.0  
ref|XP_020084535.1| Niemann-Pick C1 protein-like [Ananas comosus]     851   0.0  
ref|XP_010918252.2| PREDICTED: Niemann-Pick C1 protein-like isof...   850   0.0  
gb|POF00322.1| niemann-pick c1 protein [Quercus suber]                844   0.0  
ref|XP_023920396.1| Niemann-Pick C1 protein-like [Quercus suber]      844   0.0  
gb|OVA00612.1| Sterol-sensing domain [Macleaya cordata]               843   0.0  
emb|CBI40718.3| unnamed protein product, partial [Vitis vinifera]     840   0.0  
ref|XP_018836419.1| PREDICTED: Niemann-Pick C1 protein-like isof...   837   0.0  
ref|XP_019072216.1| PREDICTED: Niemann-Pick C1 protein [Vitis vi...   840   0.0  
gb|OAY77489.1| Niemann-Pick C1 protein [Ananas comosus]               835   0.0  
gb|KDO85105.1| hypothetical protein CISIN_1g000762mg [Citrus sin...   826   0.0  
ref|XP_018836418.1| PREDICTED: Niemann-Pick C1 protein-like isof...   837   0.0  
gb|PON90466.1| Niemann-Pick C type protein [Trema orientalis]         832   0.0  
gb|KDO85104.1| hypothetical protein CISIN_1g000762mg [Citrus sin...   826   0.0  

>ref|XP_009384014.1| PREDICTED: Niemann-Pick C1 protein-like [Musa acuminata subsp.
            malaccensis]
          Length = 1235

 Score =  970 bits (2507), Expect = 0.0
 Identities = 484/685 (70%), Positives = 550/685 (80%), Gaps = 3/685 (0%)
 Frame = +1

Query: 1    QQAIPLLVSCPACLRNFLNLFCELSCSPDQSLFINVTSVKKVNDSMTVDMIDYFITPYFG 180
            QQAIPLLV CPACLRNFLNLFCELSCSP+QSLFINVTS+KKVN ++ VD ID+F+T YFG
Sbjct: 59   QQAIPLLVGCPACLRNFLNLFCELSCSPNQSLFINVTSIKKVNGTLAVDAIDFFVTHYFG 118

Query: 181  EQLFNSCKDVKFGTLNTRAMDFVGGGAQNYTEWFAFLGHRANLSMPGSPYAIAFQSIISD 360
            EQLFNSCKDVKFG++NTRAMDFVG GA NY +W AFLG RANL +PGSPYAI F+S ISD
Sbjct: 119  EQLFNSCKDVKFGSMNTRAMDFVGAGAHNYADWLAFLGRRANLDVPGSPYAITFRSNISD 178

Query: 361  LSGVRPLNATVYSCGDTSLGCSCGDCPSSALCVGSLQPAPHVKRSCSVKIASLKVKCLDF 540
             +G++P+N TVYSCGD+SLGCSCGDCPSSA+C+ S  PA H K+SCS+ I SLK+KCLDF
Sbjct: 179  STGMKPMNTTVYSCGDSSLGCSCGDCPSSAVCLDSSTPAQHAKQSCSINIGSLKIKCLDF 238

Query: 541  SLVIVYLFLLPAFLLWGSWYQKKKADPSRTEPFFNA---NGGNSSDKQENRSPQISEAVP 711
            SL IVYLFL+ AFLLWG  Y+KK+A PSRT+   N    N  NS DK+E  S QISE VP
Sbjct: 239  SLAIVYLFLVSAFLLWGFVYRKKRAGPSRTKALLNVRDDNNHNSGDKKEAPS-QISEEVP 297

Query: 712  SVIKANRPSVVQLYLSSFFRKYGNFISRHPTXXXXXXXXXXXXXXXXXIRFKVETRPEKL 891
             V+KA+RPSV+QLY+S+FFRKYG+F+S++PT                 IRFKVETRPEKL
Sbjct: 298  PVVKAHRPSVIQLYMSNFFRKYGSFVSKNPTLILCLSLVVPLLLCLGLIRFKVETRPEKL 357

Query: 892  WVGPGSKAAKEKLYFDSHLAPFYRIEQFILANISASNGENPPNIVTEENVKLLFQIQKKV 1071
            WVGPGSKAAKEK YFDSHLAPFYRIEQ ILA IS S+ E PPNI+T++N+KLLF++QKKV
Sbjct: 358  WVGPGSKAAKEKQYFDSHLAPFYRIEQLILAGISGSDAERPPNIITDKNLKLLFELQKKV 417

Query: 1072 DDLHANYSGSVVSLPDICLKPLGNDCATQSILQYFQMDPQNYDAYGGLAHLQYCFEHFSS 1251
            DDL ANYSGS+VSL DICLKPLG DCATQS+LQYF+MDPQNYDAYGGL H+QYCF+HFSS
Sbjct: 418  DDLRANYSGSMVSLADICLKPLGKDCATQSVLQYFKMDPQNYDAYGGLDHVQYCFQHFSS 477

Query: 1252 EKSCLSAFSAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDKTSSEYRNAVAWEKAFV 1431
             ++CLSAF APLDPSTALGGFSGNNYSEASAFVITYPVNN LD+TS+EYR+AVAWEKAF+
Sbjct: 478  AENCLSAFHAPLDPSTALGGFSGNNYSEASAFVITYPVNNQLDETSTEYRSAVAWEKAFI 537

Query: 1432 QLMKDEIIPMVXXXXXXXXXXXXXXXXXXXKRESTADAITIFISYLVMFAYISVTLGNRH 1611
            +L++DE++PMV                   KRESTAD ITI +SYLVMFAYIS+ LG+R 
Sbjct: 538  RLIQDELVPMVQSQNLSLSFSSESSIQEELKRESTADVITIIVSYLVMFAYISIMLGDRG 597

Query: 1612 HLSSIFXXXXXXXXXXXXXXXXXXXXXXXXFYSAIGVKSTLIIMEVIPFLVLAVGVDNMC 1791
            HLS+ F                        FYSAIG+KSTLIIMEVIPFLVLAVGVDNMC
Sbjct: 598  HLSTFFVSSKLLLGLSGVVLVMLSVLGSVGFYSAIGIKSTLIIMEVIPFLVLAVGVDNMC 657

Query: 1792 ILVHTIKRQPLELLLEERISSALADVGPSITLASLSEVLAFAVGSFIPMPACRVFSMXXX 1971
            ILVH +KRQP ELLLEERIS+AL +VGPSITLASLSEVLAFAVGSFIPMPACRVFSM   
Sbjct: 658  ILVHAVKRQPCELLLEERISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFAA 717

Query: 1972 XXXXXXXXXQVTAFVSLIIFDFLRA 2046
                     QVTAFVSLIIFDFLRA
Sbjct: 718  LAVLLDFFLQVTAFVSLIIFDFLRA 742



 Score =  654 bits (1688), Expect = 0.0
 Identities = 326/389 (83%), Positives = 347/389 (89%)
 Frame = +2

Query: 2099 LRGVKIIVILVFSGFAFASIALCTRVQPGLEQKIVLPRDSYLQNYFDDLAKYLRVGPPLY 2278
            L GVKIIVI VF GFAFASIALCTRVQPGLEQK+VLPR+SYLQ+YFDDLAKYLRVGPPLY
Sbjct: 787  LWGVKIIVIAVFVGFAFASIALCTRVQPGLEQKVVLPRNSYLQDYFDDLAKYLRVGPPLY 846

Query: 2279 FVVKDFNYSLESRNTNQICSISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWL 2458
            FVVKDFNYSLE+RNTNQICSISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWL
Sbjct: 847  FVVKDFNYSLEARNTNQICSISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWL 906

Query: 2459 SPEAFSCCRKFLNGSYXXXXXXXXXXXXXXGLCNMGTTCKDCTTCYRYSDLHDGRPSTMD 2638
            SP+AFSCCR+F+NGSY              G C +G  CKDCTTC+RY DLHDGRPST+ 
Sbjct: 907  SPDAFSCCREFVNGSYCPPDDQPPCCQPNDGSCTLGIECKDCTTCFRYLDLHDGRPSTVQ 966

Query: 2639 FKVKLPWFLNALPSSNCAKGGKGAYTSSVDLSGYESGIIQASSFRTYHTPLNRQIDYVNS 2818
            F+ KLPWFLNALPSSNCAKGGKGAYTSSVDLSGYESGII+AS+FRTYHTPLN+Q DYVNS
Sbjct: 967  FREKLPWFLNALPSSNCAKGGKGAYTSSVDLSGYESGIIEASAFRTYHTPLNKQSDYVNS 1026

Query: 2819 MKAALDFXXXXXXXXXMEIFPYSVFYIFFEQYLDIWRTALINISIGLGAVFVVCLVLTGS 2998
            MKAA DF         MEIFPY+VFYIFFEQYLDIWRTALINISIGLGAVFVVCLVLT S
Sbjct: 1027 MKAARDFSSKMSDSLKMEIFPYAVFYIFFEQYLDIWRTALINISIGLGAVFVVCLVLTSS 1086

Query: 2999 IWVSTIILAVLVMIVIDMLGLMAILGIQLNAISVVNLVMSIGIAVEFCVHITHAFLLSSG 3178
            IW+S IIL VL MIVIDMLG+MA+L IQLNAISVVNLVMSIGIAVEFCVHITHAFL+SSG
Sbjct: 1087 IWISAIILLVLAMIVIDMLGIMAVLDIQLNAISVVNLVMSIGIAVEFCVHITHAFLVSSG 1146

Query: 3179 DRETRMKMALSTMGASVFSGITLTKLVGV 3265
            DR TR K+A+STMGASVFSGITLTKLVGV
Sbjct: 1147 DRGTRTKLAVSTMGASVFSGITLTKLVGV 1175


>gb|KDO85101.1| hypothetical protein CISIN_1g000762mg [Citrus sinensis]
          Length = 1268

 Score =  826 bits (2133), Expect(2) = 0.0
 Identities = 417/689 (60%), Positives = 506/689 (73%), Gaps = 7/689 (1%)
 Frame = +1

Query: 1    QQAIPLLVSCPACLRNFLNLFCELSCSPDQSLFINVTSVKKVNDSMTVDMIDYFITPYFG 180
            QQAIP LV CPACLRNFLNLFCEL+CSP+QSLFINVTSV KV++++TVD IDY+IT  FG
Sbjct: 113  QQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVSKVSNNLTVDGIDYYITDTFG 172

Query: 181  EQLFNSCKDVKFGTLNTRAMDFVGGGAQNYTEWFAFLGHRANLSMPGSPYAIAFQSIISD 360
            + L+ SCKDVKFGT+NTRA+DF+GGGAQN+ +WFAF+G RA  ++PGSPY I F     +
Sbjct: 173  QGLYESCKDVKFGTMNTRALDFIGGGAQNFKDWFAFIGRRAAANLPGSPYTIKFWPSAPE 232

Query: 361  LSGVRPLNATVYSCGDTSLGCSCGDCPSSALCVGSLQPAPHVKRSCSVKIASLKVKCLDF 540
            LSG+ P+N + YSC D SLGCSCGDC SS +C  S  P PH   SCSVK+ SL  KC+DF
Sbjct: 233  LSGMIPMNVSAYSCADGSLGCSCGDCTSSPVC-SSTAPPPHKSSSCSVKMGSLNAKCVDF 291

Query: 541  SLVIVYLFLLPAFLLWGSWYQKKKADPS-RTEPFFNANGGNS-----SDKQENRSPQISE 702
            +L I+Y+ L+  F  WG +++K++   S R +P  NA  G+        K+EN   Q+  
Sbjct: 292  ALAILYIILVSLFFGWGFFHRKRERSRSFRMKPLVNAMDGSELHSVERQKEENLPMQVQM 351

Query: 703  -AVPSVIKANRPSVVQLYLSSFFRKYGNFISRHPTXXXXXXXXXXXXXXXXXIRFKVETR 879
               P      + S+VQ Y+S+F+RKYG +++R+PT                 IRF+VETR
Sbjct: 352  LGTPRTRNRIQLSIVQGYMSNFYRKYGKWVARNPTLVLSLSMALVLLLCLGLIRFEVETR 411

Query: 880  PEKLWVGPGSKAAKEKLYFDSHLAPFYRIEQFILANISASNGENPPNIVTEENVKLLFQI 1059
            PEKLWVGPGS+AA+EKL+FDSHLAPFYRIE+ ILA I  +   N P+IVTE N+KLLF+I
Sbjct: 412  PEKLWVGPGSRAAEEKLFFDSHLAPFYRIEELILATIPDTTHGNLPSIVTESNIKLLFEI 471

Query: 1060 QKKVDDLHANYSGSVVSLPDICLKPLGNDCATQSILQYFQMDPQNYDAYGGLAHLQYCFE 1239
            QKK+D L ANYSGS++SL DIC+KPLG DCATQS+LQYF+MDP+N+D +GG+ H++YCF+
Sbjct: 472  QKKIDGLRANYSGSMISLTDICMKPLGQDCATQSVLQYFKMDPKNFDDFGGVEHVKYCFQ 531

Query: 1240 HFSSEKSCLSAFSAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDKTSSEYRNAVAWE 1419
            H++S +SC+SAF  PLDPSTALGGFSGNNYSEASAFV+TYPVNN +D+  +E + AVAWE
Sbjct: 532  HYTSTESCMSAFKGPLDPSTALGGFSGNNYSEASAFVVTYPVNNAVDREGNETKKAVAWE 591

Query: 1420 KAFVQLMKDEIIPMVXXXXXXXXXXXXXXXXXXXKRESTADAITIFISYLVMFAYISVTL 1599
            KAFVQL KDE++PMV                   KRESTADAITI ISYLVMFAYIS+TL
Sbjct: 592  KAFVQLAKDELLPMVQSKNLTLAFSSESSIEEELKRESTADAITIVISYLVMFAYISLTL 651

Query: 1600 GNRHHLSSIFXXXXXXXXXXXXXXXXXXXXXXXXFYSAIGVKSTLIIMEVIPFLVLAVGV 1779
            G+  HLSS +                        F+SAIGVKSTLIIMEVIPFLVLAVGV
Sbjct: 652  GDTPHLSSFYISSKVLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVGV 711

Query: 1780 DNMCILVHTIKRQPLELLLEERISSALADVGPSITLASLSEVLAFAVGSFIPMPACRVFS 1959
            DNMCILVH +KRQ LEL LE RIS+AL +VGPSITLASLSEVLAFAVGSFIPMPACRVFS
Sbjct: 712  DNMCILVHAVKRQQLELPLETRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFS 771

Query: 1960 MXXXXXXXXXXXXQVTAFVSLIIFDFLRA 2046
            M            Q+TAFV+LI+FDFLRA
Sbjct: 772  MFAALAVLLDFLLQITAFVALIVFDFLRA 800



 Score =  559 bits (1441), Expect(2) = 0.0
 Identities = 268/369 (72%), Positives = 310/369 (84%)
 Frame = +2

Query: 2159 ALCTRVQPGLEQKIVLPRDSYLQNYFDDLAKYLRVGPPLYFVVKDFNYSLESRNTNQICS 2338
            ALCTR++PGLEQKIVLPRDSYLQ YF++++++LR+GPPLYFVVK++NYS ESR TNQ+CS
Sbjct: 838  ALCTRIEPGLEQKIVLPRDSYLQGYFNNISEHLRIGPPLYFVVKNYNYSSESRQTNQLCS 897

Query: 2339 ISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWLSPEAFSCCRKFLNGSYXXXX 2518
            ISQCDSNSLLNEI++ASL+P SSYIAKPAASWLDDFL+W+SPEAF CCRKF NGSY    
Sbjct: 898  ISQCDSNSLLNEISRASLIPQSSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPD 957

Query: 2519 XXXXXXXXXXGLCNMGTTCKDCTTCYRYSDLHDGRPSTMDFKVKLPWFLNALPSSNCAKG 2698
                        C     CKDCTTC+ +SDL   RPST+ FK KLPWFLNALPS++CAKG
Sbjct: 958  DQPPCCPSGQSSCGSAGVCKDCTTCFHHSDLLKDRPSTIQFKEKLPWFLNALPSASCAKG 1017

Query: 2699 GKGAYTSSVDLSGYESGIIQASSFRTYHTPLNRQIDYVNSMKAALDFXXXXXXXXXMEIF 2878
            G GAYT+SVDL GYE+GI+QASSFRTYHTPLNRQIDYVNSM+AA +F         MEIF
Sbjct: 1018 GHGAYTNSVDLKGYENGIVQASSFRTYHTPLNRQIDYVNSMRAAREFSSRVSDSLQMEIF 1077

Query: 2879 PYSVFYIFFEQYLDIWRTALINISIGLGAVFVVCLVLTGSIWVSTIILAVLVMIVIDMLG 3058
            PYSVFY++FEQYLDIWRTALIN++I +GAVFVVCL+ T S W S IIL VL MIV+D++G
Sbjct: 1078 PYSVFYMYFEQYLDIWRTALINLAIAIGAVFVVCLITTCSFWSSAIILLVLTMIVVDLMG 1137

Query: 3059 LMAILGIQLNAISVVNLVMSIGIAVEFCVHITHAFLLSSGDRETRMKMALSTMGASVFSG 3238
            +MAIL IQLNA+SVVNLVM++GIAVEFCVHITHAF +SSGD+  RMK AL TMGASVFSG
Sbjct: 1138 VMAILKIQLNAVSVVNLVMAVGIAVEFCVHITHAFSVSSGDKNQRMKEALGTMGASVFSG 1197

Query: 3239 ITLTKLVGV 3265
            ITLTKLVGV
Sbjct: 1198 ITLTKLVGV 1206


>gb|PIA46755.1| hypothetical protein AQUCO_01500358v1 [Aquilegia coerulea]
          Length = 1274

 Score =  807 bits (2085), Expect(2) = 0.0
 Identities = 407/687 (59%), Positives = 497/687 (72%), Gaps = 5/687 (0%)
 Frame = +1

Query: 1    QQAIPLLVSCPACLRNFLNLFCELSCSPDQSLFINVTSVKKVNDSMTVDMIDYFITPYFG 180
            QQAIP LV CPACLRNFLNLFCEL+CSP+QS FINVTS+ KVN+++TV+ ID+++T  FG
Sbjct: 120  QQAIPFLVGCPACLRNFLNLFCELTCSPNQSQFINVTSISKVNNNLTVNGIDFYLTDAFG 179

Query: 181  EQLFNSCKDVKFGTLNTRAMDFVGGGAQNYTEWFAFLGHRANLSMPGSPYAIAFQSIISD 360
            E+L+NSCKDVKFGT+NTRA++F+G GA N  EW AF+G RA   +PGSPYAI FQS   +
Sbjct: 180  EELYNSCKDVKFGTMNTRAIEFIGAGANNIKEWLAFIGKRAGNDVPGSPYAINFQSKTQE 239

Query: 361  LSGVRPLNATVYSCGDTSLGCSCGDCPSSALCVGSLQPAPHVKRSCSVKIASLKVKCLDF 540
             SG+ P+N +VYSCGDTSLGCSCGDCPSSA+C  S   + H K SCS+KI SL+VKC++ 
Sbjct: 240  SSGMMPMNVSVYSCGDTSLGCSCGDCPSSAICSSSAPSSFHKKHSCSIKIGSLQVKCVEL 299

Query: 541  SLVIVYLFLLPAFLLWGSWYQKKKADPSRTEPFFNANGGN-----SSDKQENRSPQISEA 705
            +L I+Y  L+  F  WG ++++K    SR     +  GG      S  K ++   Q+S  
Sbjct: 300  TLAILYGVLVMTFFGWGVFHRRKSIPVSRNNNLASVAGGGEQHYISKQKDDSHPLQMSHE 359

Query: 706  VPSVIKANRPSVVQLYLSSFFRKYGNFISRHPTXXXXXXXXXXXXXXXXXIRFKVETRPE 885
            +P  IK  +  +VQ Y+SSF+R+YG +++R+PT                 IRF+VETRPE
Sbjct: 360  LPRAIKGVQLPLVQGYMSSFYRRYGIWVARNPTLVLFSSLAVVLCLCLGLIRFEVETRPE 419

Query: 886  KLWVGPGSKAAKEKLYFDSHLAPFYRIEQFILANISASNGENPPNIVTEENVKLLFQIQK 1065
            KLWVG GSKAA+EK +FD+HLAPFYRIEQ ILA I  S     P IVT+EN  LLF+IQK
Sbjct: 420  KLWVGHGSKAAEEKRFFDTHLAPFYRIEQLILATIPDSKQGKSPGIVTDENFHLLFEIQK 479

Query: 1066 KVDDLHANYSGSVVSLPDICLKPLGNDCATQSILQYFQMDPQNYDAYGGLAHLQYCFEHF 1245
            KVD + ANYSGS+VSL DIC KPLG DCATQS+LQYF+MDP+NYD  GG+ H QYCF+ +
Sbjct: 480  KVDRIQANYSGSMVSLTDICSKPLGKDCATQSVLQYFKMDPKNYDDLGGVEHAQYCFQQY 539

Query: 1246 SSEKSCLSAFSAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDKTSSEYRNAVAWEKA 1425
            +S  +C++AF  PLDP+TALGGFS NNYSEASAFV+TYPVNN +D+TSS    AVAWEKA
Sbjct: 540  TSAATCMTAFKGPLDPTTALGGFSANNYSEASAFVVTYPVNNNVDQTSSGNGKAVAWEKA 599

Query: 1426 FVQLMKDEIIPMVXXXXXXXXXXXXXXXXXXXKRESTADAITIFISYLVMFAYISVTLGN 1605
            F++L K+E++PM                    KRESTAD ITI ISY+VMFAYIS+TLG+
Sbjct: 600  FIRLAKEELMPMAQSHNLTLSFSSESSIQEELKRESTADVITILISYIVMFAYISLTLGD 659

Query: 1606 RHHLSSIFXXXXXXXXXXXXXXXXXXXXXXXXFYSAIGVKSTLIIMEVIPFLVLAVGVDN 1785
              H+SS +                        F+SA+GVKSTLIIMEVIPFLVLAVGVDN
Sbjct: 660  APHISSFYISSKVLLGLSGVLVVMLSVLGSVGFFSAVGVKSTLIIMEVIPFLVLAVGVDN 719

Query: 1786 MCILVHTIKRQPLELLLEERISSALADVGPSITLASLSEVLAFAVGSFIPMPACRVFSMX 1965
            MCILVH +KRQP+EL LEER+S+AL +VGPSITLASLSEVLAFAVGSFIPMPACRVFSM 
Sbjct: 720  MCILVHAVKRQPVELPLEERMSNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMF 779

Query: 1966 XXXXXXXXXXXQVTAFVSLIIFDFLRA 2046
                       QVTAFV+LI+FDFLRA
Sbjct: 780  AALAVLLDFLLQVTAFVALIVFDFLRA 806



 Score =  546 bits (1406), Expect(2) = 0.0
 Identities = 259/369 (70%), Positives = 309/369 (83%)
 Frame = +2

Query: 2159 ALCTRVQPGLEQKIVLPRDSYLQNYFDDLAKYLRVGPPLYFVVKDFNYSLESRNTNQICS 2338
            AL TR+QPGLEQK+VLP+DSYLQ YF+++++YLR+GPPLYFVVK++NYSLESR TNQ+CS
Sbjct: 844  ALSTRIQPGLEQKVVLPQDSYLQGYFNNISEYLRIGPPLYFVVKNYNYSLESRQTNQLCS 903

Query: 2339 ISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWLSPEAFSCCRKFLNGSYXXXX 2518
            ISQCD+NSLL+EI +ASL P  SYIAKPAASWLDDFL+W+SPEAF CCRKF NG+Y    
Sbjct: 904  ISQCDTNSLLSEIARASLTPKESYIAKPAASWLDDFLVWMSPEAFGCCRKFTNGTYCPPD 963

Query: 2519 XXXXXXXXXXGLCNMGTTCKDCTTCYRYSDLHDGRPSTMDFKVKLPWFLNALPSSNCAKG 2698
                      GLC++G  C DCTTC+R+ DL + RPST  FK KLPWFLNALPS++CAKG
Sbjct: 964  DQPPCCSPDQGLCSLGGVCSDCTTCFRHLDLRNDRPSTAQFKEKLPWFLNALPSADCAKG 1023

Query: 2699 GKGAYTSSVDLSGYESGIIQASSFRTYHTPLNRQIDYVNSMKAALDFXXXXXXXXXMEIF 2878
            G GAYT+S+DL+GYESG+I AS FRTYHTPLN+Q D+VNSM+AA +F         M+IF
Sbjct: 1024 GHGAYTNSLDLNGYESGVITASEFRTYHTPLNKQSDFVNSMRAAREFSSRVSNTLKMDIF 1083

Query: 2879 PYSVFYIFFEQYLDIWRTALINISIGLGAVFVVCLVLTGSIWVSTIILAVLVMIVIDMLG 3058
            PYSV YIFFEQYLDIWRTALIN+++ LGAVF+VC ++T S+W S II+ VL M+V+D++G
Sbjct: 1084 PYSVAYIFFEQYLDIWRTALINLAMALGAVFIVCWLITCSLWSSAIIIFVLAMVVVDLMG 1143

Query: 3059 LMAILGIQLNAISVVNLVMSIGIAVEFCVHITHAFLLSSGDRETRMKMALSTMGASVFSG 3238
            +MAIL IQLNA+SVVNLVMSIGIAVEFCVHITHAF +S+GDRE R K ALSTMGASV SG
Sbjct: 1144 VMAILNIQLNAVSVVNLVMSIGIAVEFCVHITHAFSVSNGDREHRAKEALSTMGASVLSG 1203

Query: 3239 ITLTKLVGV 3265
            ITLTKLVGV
Sbjct: 1204 ITLTKLVGV 1212


>ref|XP_022762939.1| Niemann-Pick C1 protein isoform X4 [Durio zibethinus]
          Length = 1258

 Score =  782 bits (2020), Expect(2) = 0.0
 Identities = 392/688 (56%), Positives = 491/688 (71%), Gaps = 6/688 (0%)
 Frame = +1

Query: 1    QQAIPLLVSCPACLRNFLNLFCELSCSPDQSLFINVTSVKKVNDSMTVDMIDYFITPYFG 180
            QQAIP LV CP+CLRNFLNLFCELSCSP+QSLFINVTSV +VN ++TVD ID++++  FG
Sbjct: 111  QQAIPFLVGCPSCLRNFLNLFCELSCSPNQSLFINVTSVSEVNGNLTVDGIDFYVSNAFG 170

Query: 181  EQLFNSCKDVKFGTLNTRAMDFVGGGAQNYTEWFAFLGHRANLSMPGSPYAIAFQSIISD 360
            E L++SCK+VKFGT+NTRA++F+G GA N+ EWF F+G +A    PGSPYAI F+S + D
Sbjct: 171  EGLYDSCKEVKFGTMNTRAIEFIGAGATNFKEWFEFIGQKAPPGFPGSPYAINFKSTVPD 230

Query: 361  LSGVRPLNATVYSCGDTSLGCSCGDCPSSALCVGSLQPAPHVKRSCSVKIASLKVKCLDF 540
             SG+  +N + YSCGDTSLGCSCGDCPSS  C     P+P  K  CS+ I  +KV+C+DF
Sbjct: 231  FSGMELMNVSSYSCGDTSLGCSCGDCPSSPQCSNFEPPSPPEKDHCSITIGPVKVRCMDF 290

Query: 541  SLVIVYLFLLPAFLLWGSWYQ-KKKADPSRTEPFFNANGGNSS-----DKQENRSPQISE 702
            +L I Y+ L+   L W  +++ +++   S  EP   +  G+ +     +  EN + +  E
Sbjct: 291  ALAIAYIILVLGLLGWVLFHRPRERRAASDREPLLKSIDGDEANYANMEYDENLALKGRE 350

Query: 703  AVPSVIKANRPSVVQLYLSSFFRKYGNFISRHPTXXXXXXXXXXXXXXXXXIRFKVETRP 882
              P +    + SV+Q Y+SSF+R YG +++R+PT                 IRF+VETRP
Sbjct: 351  VAPHLTNGVQLSVIQGYMSSFYRSYGRWVARNPTVVLCLSFAVVIVLCFGLIRFEVETRP 410

Query: 883  EKLWVGPGSKAAKEKLYFDSHLAPFYRIEQFILANISASNGENPPNIVTEENVKLLFQIQ 1062
            EKLWVG GSKAA+EK +FDS LAPFYRIEQ ILA +       PP+IVT++N++LLF+IQ
Sbjct: 411  EKLWVGHGSKAAEEKQFFDSQLAPFYRIEQLILATLPDKTRGKPPSIVTDDNIQLLFEIQ 470

Query: 1063 KKVDDLHANYSGSVVSLPDICLKPLGNDCATQSILQYFQMDPQNYDAYGGLAHLQYCFEH 1242
            +KVD++ ANYSGS +SL DICLKPLG DCATQS+LQYF MD +N++ YGG+ H +YCF+H
Sbjct: 471  EKVDEIRANYSGSTLSLTDICLKPLGQDCATQSVLQYFMMDRENFENYGGVTHAEYCFQH 530

Query: 1243 FSSEKSCLSAFSAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDKTSSEYRNAVAWEK 1422
            +++  +CLSAF APLDPSTALGGFSGNNYSEASAFV+TYPVNN +D+  +    AVAWEK
Sbjct: 531  YTTSDTCLSAFKAPLDPSTALGGFSGNNYSEASAFVVTYPVNNAIDEAGNGNGKAVAWEK 590

Query: 1423 AFVQLMKDEIIPMVXXXXXXXXXXXXXXXXXXXKRESTADAITIFISYLVMFAYISVTLG 1602
            AF+QL+K+E++PMV                   KRESTAD ITI +SYLVMFAYIS+TLG
Sbjct: 591  AFIQLVKEELLPMVQSRNLTLSFSSESSIEEELKRESTADIITIVVSYLVMFAYISITLG 650

Query: 1603 NRHHLSSIFXXXXXXXXXXXXXXXXXXXXXXXXFYSAIGVKSTLIIMEVIPFLVLAVGVD 1782
            +   LS+ +                        F+SA GVKSTLIIMEVIPFLVLAVGVD
Sbjct: 651  DAPRLSTFYISSKVLLGFSGVILVMLSVLGSVGFFSAFGVKSTLIIMEVIPFLVLAVGVD 710

Query: 1783 NMCILVHTIKRQPLELLLEERISSALADVGPSITLASLSEVLAFAVGSFIPMPACRVFSM 1962
            NMCILVH +KRQPLEL LEERIS+AL +VGPSITLASLSE+LAFAVG FIPMPACRVFS+
Sbjct: 711  NMCILVHAVKRQPLELPLEERISNALVEVGPSITLASLSEILAFAVGGFIPMPACRVFSL 770

Query: 1963 XXXXXXXXXXXXQVTAFVSLIIFDFLRA 2046
                        QVTAFVSLI+FD LRA
Sbjct: 771  FAALAVLLDFLLQVTAFVSLIVFDCLRA 798



 Score =  553 bits (1425), Expect(2) = 0.0
 Identities = 264/369 (71%), Positives = 315/369 (85%)
 Frame = +2

Query: 2159 ALCTRVQPGLEQKIVLPRDSYLQNYFDDLAKYLRVGPPLYFVVKDFNYSLESRNTNQICS 2338
            AL TR++ GLEQ+IVLPRDSYLQ YF +++++LR+GPPLYFVVKD+NYSLESR+TN++CS
Sbjct: 836  ALSTRIESGLEQQIVLPRDSYLQGYFTNVSEFLRIGPPLYFVVKDYNYSLESRDTNKLCS 895

Query: 2339 ISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWLSPEAFSCCRKFLNGSYXXXX 2518
            I+QCDSNSLLNEI++ASLVP SSYIAKPAASWLDDFL+WLSPEAF CCRKF NG+Y    
Sbjct: 896  INQCDSNSLLNEISRASLVPESSYIAKPAASWLDDFLVWLSPEAFGCCRKFTNGTYCPPD 955

Query: 2519 XXXXXXXXXXGLCNMGTTCKDCTTCYRYSDLHDGRPSTMDFKVKLPWFLNALPSSNCAKG 2698
                      G C +G  CKDCTTC+R+SDL + RPST  FK KLPWFLNALPS++CAKG
Sbjct: 956  DQPPCCSPDGGSCGLGGICKDCTTCFRHSDLVNDRPSTEQFKDKLPWFLNALPSADCAKG 1015

Query: 2699 GKGAYTSSVDLSGYESGIIQASSFRTYHTPLNRQIDYVNSMKAALDFXXXXXXXXXMEIF 2878
            G GAYTSSVDL+GYESG+I+AS FRTYHTPLNRQ DYVN+++AA +F         M++F
Sbjct: 1016 GHGAYTSSVDLNGYESGVIKASEFRTYHTPLNRQGDYVNALRAAREFSLRISDSLKMQVF 1075

Query: 2879 PYSVFYIFFEQYLDIWRTALINISIGLGAVFVVCLVLTGSIWVSTIILAVLVMIVIDMLG 3058
            PYSVFYIFFEQYLDIW  AL+NI+I LGA+F+VCLV+T S+W+S IIL VLVM+V+D++G
Sbjct: 1076 PYSVFYIFFEQYLDIWGIALMNIAIALGAIFIVCLVITSSLWISAIILLVLVMLVVDLMG 1135

Query: 3059 LMAILGIQLNAISVVNLVMSIGIAVEFCVHITHAFLLSSGDRETRMKMALSTMGASVFSG 3238
            +MAIL IQLNA+SVVNLVMSIGIAVEFCVHI +AFL+S+GDR+ RMK AL T+GASVFSG
Sbjct: 1136 VMAILDIQLNAVSVVNLVMSIGIAVEFCVHIANAFLVSNGDRDQRMKEALGTIGASVFSG 1195

Query: 3239 ITLTKLVGV 3265
            ITLTKLVGV
Sbjct: 1196 ITLTKLVGV 1204


>ref|XP_019705210.1| PREDICTED: Niemann-Pick C1 protein-like isoform X2 [Elaeis
            guineensis]
          Length = 1082

 Score =  738 bits (1906), Expect(2) = 0.0
 Identities = 381/614 (62%), Positives = 448/614 (72%), Gaps = 6/614 (0%)
 Frame = +1

Query: 223  LNTRAMDFVGGGAQNYTEWFAFLGHRANLSMPGSPYAIAFQSIISDLSGVRPLNATVYSC 402
            +NTRAMDFVG GAQNY EW AF+GH+AN + PGSPYAIAFQ I  D SG++P+N TVYSC
Sbjct: 1    MNTRAMDFVGAGAQNYKEWLAFIGHQANPNEPGSPYAIAFQ-IDVDSSGMKPMNVTVYSC 59

Query: 403  GDTSLGCSCGDCPSSALCVGSLQPAPHVKRSCSVKIASLKVKCLDFSLVIVYLFLLPAFL 582
            GD SLGCSCGDCPSS++C  S  PAP  K++C+++I SLKVKCLDFSL I+YL  + A L
Sbjct: 60   GDPSLGCSCGDCPSSSVCSDSASPAPREKQACAIRIGSLKVKCLDFSLAILYLLTISAIL 119

Query: 583  LWGSWYQKK-KADPSRTEPFFNANGGN---SSDKQE--NRSPQISEAVPSVIKANRPSVV 744
             WG  ++K+ +  PSRT+ F N    N   S +KQE   +  Q+SE VP+V+    PSVV
Sbjct: 120  AWGLLHRKQERTGPSRTKLFLNVKDENELHSVNKQEISTQPNQVSEEVPAVVTMLHPSVV 179

Query: 745  QLYLSSFFRKYGNFISRHPTXXXXXXXXXXXXXXXXXIRFKVETRPEKLWVGPGSKAAKE 924
            Q Y+ +FFR YG+F+SR+PT                 I FKVET+PEKLWVGP SKAA+E
Sbjct: 180  QGYILNFFRIYGSFVSRNPTLVLCLSLAVPLLLCIGLIHFKVETQPEKLWVGPRSKAAEE 239

Query: 925  KLYFDSHLAPFYRIEQFILANISASNGENPPNIVTEENVKLLFQIQKKVDDLHANYSGSV 1104
            K YFDSHLAPFYRIEQ ILA +  S  E PP+IVTE+N+KLLF+IQKK+D L AN+SGS 
Sbjct: 240  KQYFDSHLAPFYRIEQLILATVPVSKHEKPPSIVTEKNIKLLFEIQKKIDGLRANFSGST 299

Query: 1105 VSLPDICLKPLGNDCATQSILQYFQMDPQNYDAYGGLAHLQYCFEHFSSEKSCLSAFSAP 1284
            V L DICLKPLG DCATQS+LQYF+MDP+NYD +GG+ H +YCF+H+SS ++CLSAF AP
Sbjct: 300  VFLTDICLKPLGEDCATQSVLQYFKMDPENYDGFGGVDHAEYCFQHYSSAETCLSAFQAP 359

Query: 1285 LDPSTALGGFSGNNYSEASAFVITYPVNNVLDKTSSEYRNAVAWEKAFVQLMKDEIIPMV 1464
            LDP+TALGGF+G+NYSEASAFVITYPVNN  DK   E   AVAWEKAF+ L+K+E+ PMV
Sbjct: 360  LDPATALGGFTGSNYSEASAFVITYPVNNEADKNGKENGKAVAWEKAFIHLVKEELRPMV 419

Query: 1465 XXXXXXXXXXXXXXXXXXXKRESTADAITIFISYLVMFAYISVTLGNRHHLSSIFXXXXX 1644
                               KRESTAD ITI +SYLVMFAYIS TLG+  H+SS       
Sbjct: 420  QLQNLTLSFSSESSVQEELKRESTADVITIVVSYLVMFAYISFTLGDSPHMSSFIVSSKV 479

Query: 1645 XXXXXXXXXXXXXXXXXXXFYSAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHTIKRQPL 1824
                               F+SAIGVKSTLIIMEVIPFLVLAVGVDNMCILVH +KRQ L
Sbjct: 480  LLGLSGVVLVMLSVLGSIGFFSAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQSL 539

Query: 1825 ELLLEERISSALADVGPSITLASLSEVLAFAVGSFIPMPACRVFSMXXXXXXXXXXXXQV 2004
            EL LEERI++AL +VGPSITLASLSE+LAFAVGSFIPMPACRVFSM            QV
Sbjct: 540  ELPLEERITNALVEVGPSITLASLSEILAFAVGSFIPMPACRVFSMFAALAVLLDFLLQV 599

Query: 2005 TAFVSLIIFDFLRA 2046
            TAFV+LIIFDFLRA
Sbjct: 600  TAFVALIIFDFLRA 613



 Score =  602 bits (1552), Expect(2) = 0.0
 Identities = 293/369 (79%), Positives = 326/369 (88%)
 Frame = +2

Query: 2159 ALCTRVQPGLEQKIVLPRDSYLQNYFDDLAKYLRVGPPLYFVVKDFNYSLESRNTNQICS 2338
            ALCTR+QPGLEQK+VLPRDSYLQ+YFDDLAKYLRVGPPLYFVVKDFNYSLES+ TN+ICS
Sbjct: 650  ALCTRLQPGLEQKVVLPRDSYLQDYFDDLAKYLRVGPPLYFVVKDFNYSLESKQTNKICS 709

Query: 2339 ISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWLSPEAFSCCRKFLNGSYXXXX 2518
            IS+CDSNSLLNEI KASL+P SSYIAKPAASWLDDFLIWLSPEAFSCCRKF+NGSY    
Sbjct: 710  ISRCDSNSLLNEIAKASLIPESSYIAKPAASWLDDFLIWLSPEAFSCCRKFVNGSYCPPD 769

Query: 2519 XXXXXXXXXXGLCNMGTTCKDCTTCYRYSDLHDGRPSTMDFKVKLPWFLNALPSSNCAKG 2698
                      G C +G  CKDCTTC+RYS+LHDGRPS + FK KLPWFLNALPSS+CAKG
Sbjct: 770  DQPPCCQPDEGSCGVGGICKDCTTCFRYSELHDGRPSMVQFKEKLPWFLNALPSSDCAKG 829

Query: 2699 GKGAYTSSVDLSGYESGIIQASSFRTYHTPLNRQIDYVNSMKAALDFXXXXXXXXXMEIF 2878
            GKGAYT+SVDL+GYESGIIQA+SFRTYHTPLN+Q DYVNSM+AA DF         M+IF
Sbjct: 830  GKGAYTTSVDLTGYESGIIQAASFRTYHTPLNKQSDYVNSMRAARDFSSKISDSLKMQIF 889

Query: 2879 PYSVFYIFFEQYLDIWRTALINISIGLGAVFVVCLVLTGSIWVSTIILAVLVMIVIDMLG 3058
            PYS+FYIFFEQYLDIW+TAL +ISIGLGAVF+VCLV+T S+W STIIL VL MIV+DM+G
Sbjct: 890  PYSMFYIFFEQYLDIWKTALTDISIGLGAVFIVCLVITCSLWTSTIILIVLGMIVVDMMG 949

Query: 3059 LMAILGIQLNAISVVNLVMSIGIAVEFCVHITHAFLLSSGDRETRMKMALSTMGASVFSG 3238
            +MAIL IQLNA+SVVNLVMSIGIAVEFCVHITHAF +S+GDR+TR+K ALSTMGASVFSG
Sbjct: 950  VMAILEIQLNAVSVVNLVMSIGIAVEFCVHITHAFSVSNGDRQTRVKKALSTMGASVFSG 1009

Query: 3239 ITLTKLVGV 3265
            ITLTKLVGV
Sbjct: 1010 ITLTKLVGV 1018


>ref|XP_009384608.1| PREDICTED: Niemann-Pick C1 protein-like isoform X1 [Musa acuminata
            subsp. malaccensis]
          Length = 1271

 Score =  901 bits (2329), Expect = 0.0
 Identities = 463/687 (67%), Positives = 527/687 (76%), Gaps = 5/687 (0%)
 Frame = +1

Query: 1    QQAIPLLVSCPACLRNFLNLFCELSCSPDQSLFINVTSVKKVNDS-MTVDMIDYFITPYF 177
            QQ IPLLV CPACLRNFLNLFCEL CSP+QSLF NVTSVKKVN + M VD ID+++T YF
Sbjct: 101  QQVIPLLVGCPACLRNFLNLFCELVCSPNQSLFTNVTSVKKVNGNRMAVDAIDFYVTHYF 160

Query: 178  GEQLFNSCKDVKFGTLNTRAMDFVGGGAQNYTEWFAFLGHRANLSMPGSPYAIAFQSIIS 357
            GEQLFNSCKDVKFGT+NTRAMDF+G GA+NY EWFA+LGH+AN + PGSPYAI F+S  +
Sbjct: 161  GEQLFNSCKDVKFGTMNTRAMDFIGAGAKNYPEWFAYLGHQANSNEPGSPYAITFRSKSN 220

Query: 358  DLSGVRPLNATVYSCGDTSLGCSCGDCPSSALCVGSLQPAPHVKRSCSVKIASLKVKCLD 537
            D SG+ P+N T YSC D+SLGCSCGDCPSS++C  SL PAPHVK+ CS+KI SLKVKCLD
Sbjct: 221  DSSGMMPMNVTAYSCVDSSLGCSCGDCPSSSVCFDSLPPAPHVKQFCSIKIVSLKVKCLD 280

Query: 538  FSLVIVYLFLLPAFLLWGSWYQKKKADPSRTEPFFNANGG---NSSDKQENRS-PQISEA 705
             SL I YLFL+ AFLLWG  Y+K++ D  RT+P  N N     NS +KQE     QISEA
Sbjct: 281  LSLAIGYLFLISAFLLWGFVYRKERTDSLRTKPSINVNEESKLNSDEKQEILCISQISEA 340

Query: 706  VPSVIKANRPSVVQLYLSSFFRKYGNFISRHPTXXXXXXXXXXXXXXXXXIRFKVETRPE 885
             P V+KA +P V Q Y+S FFRKYG+F+S+HPT                 I F++ETRPE
Sbjct: 341  -PPVVKAQQP-VAQRYMSDFFRKYGSFVSKHPTLVLCLSLAVPLLLCLGLIHFEMETRPE 398

Query: 886  KLWVGPGSKAAKEKLYFDSHLAPFYRIEQFILANISASNGENPPNIVTEENVKLLFQIQK 1065
            KLWVGPGSK AKEK +FDS L PFYRIEQ ILA+I  SNGE  P+IVT++N+KLLF++QK
Sbjct: 399  KLWVGPGSKTAKEKQFFDSTLGPFYRIEQLILASILDSNGERAPSIVTDKNLKLLFELQK 458

Query: 1066 KVDDLHANYSGSVVSLPDICLKPLGNDCATQSILQYFQMDPQNYDAYGGLAHLQYCFEHF 1245
            KVD L ANYSGS+VSL DICLKPLG +CATQS+LQYF+MDPQNYDAYGGL H+QYCF+HF
Sbjct: 459  KVDGLRANYSGSMVSLTDICLKPLGRNCATQSVLQYFKMDPQNYDAYGGLDHVQYCFQHF 518

Query: 1246 SSEKSCLSAFSAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDKTSSEYRNAVAWEKA 1425
            SS + CLS F APLDPSTALGGFSG+NYSEA AFVITYPVNN LDK S+EY  +VAWEKA
Sbjct: 519  SSAEKCLSEFQAPLDPSTALGGFSGSNYSEALAFVITYPVNNELDKKSTEYAKSVAWEKA 578

Query: 1426 FVQLMKDEIIPMVXXXXXXXXXXXXXXXXXXXKRESTADAITIFISYLVMFAYISVTLGN 1605
            FV+LM+DE++PMV                   KRESTAD ITI +SYLVMFAYIS+TLG+
Sbjct: 579  FVRLMQDELVPMVQPQNLTLSFSSESSIEEELKRESTADVITILVSYLVMFAYISITLGD 638

Query: 1606 RHHLSSIFXXXXXXXXXXXXXXXXXXXXXXXXFYSAIGVKSTLIIMEVIPFLVLAVGVDN 1785
            R  LSS F                        FYS IGVKSTLIIMEVIPFLVLAVGVDN
Sbjct: 639  RCQLSSSFVSSKVLLGLSGVVLVMLSVLGSVGFYSIIGVKSTLIIMEVIPFLVLAVGVDN 698

Query: 1786 MCILVHTIKRQPLELLLEERISSALADVGPSITLASLSEVLAFAVGSFIPMPACRVFSMX 1965
            MCILVH +KRQPLEL+LEERIS+AL +VGPSITLASLSEV+AFAVGSFIPMPACRVFSM 
Sbjct: 699  MCILVHAVKRQPLELVLEERISNALVEVGPSITLASLSEVMAFAVGSFIPMPACRVFSMF 758

Query: 1966 XXXXXXXXXXXQVTAFVSLIIFDFLRA 2046
                       QVTAFVSLIIFDFLRA
Sbjct: 759  AALAVLLDFILQVTAFVSLIIFDFLRA 785



 Score =  642 bits (1655), Expect = 0.0
 Identities = 316/389 (81%), Positives = 343/389 (88%)
 Frame = +2

Query: 2099 LRGVKIIVILVFSGFAFASIALCTRVQPGLEQKIVLPRDSYLQNYFDDLAKYLRVGPPLY 2278
            L+GVKI+V+ VF GFAFASIALCTRVQPGLEQK+VLPRDSYLQ+YFDD+AKYLRVGPPLY
Sbjct: 830  LQGVKIVVVAVFFGFAFASIALCTRVQPGLEQKVVLPRDSYLQSYFDDIAKYLRVGPPLY 889

Query: 2279 FVVKDFNYSLESRNTNQICSISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWL 2458
            FV+KDFNYSLESRNTNQICSISQCD NS LNEITKASLVP+SSYIAKPAASWLDDFLIWL
Sbjct: 890  FVLKDFNYSLESRNTNQICSISQCDPNSFLNEITKASLVPSSSYIAKPAASWLDDFLIWL 949

Query: 2459 SPEAFSCCRKFLNGSYXXXXXXXXXXXXXXGLCNMGTTCKDCTTCYRYSDLHDGRPSTMD 2638
            SPEAFSCCR+FLNGSY              GLC  G  CKDCTTC+ YSDLHDGRPST+ 
Sbjct: 950  SPEAFSCCREFLNGSYCPPDDQPPCCQPNDGLCTTGVECKDCTTCFLYSDLHDGRPSTVQ 1009

Query: 2639 FKVKLPWFLNALPSSNCAKGGKGAYTSSVDLSGYESGIIQASSFRTYHTPLNRQIDYVNS 2818
            F  KLPWFL+ALPSSNCAKGGKGAYTSSV++SGYESGIIQAS+FRTYHTPL++Q DYVNS
Sbjct: 1010 FMEKLPWFLSALPSSNCAKGGKGAYTSSVNISGYESGIIQASAFRTYHTPLSKQSDYVNS 1069

Query: 2819 MKAALDFXXXXXXXXXMEIFPYSVFYIFFEQYLDIWRTALINISIGLGAVFVVCLVLTGS 2998
            MKAA DF         MEIFPYSVFYIFFEQYLDIWRTALINISIGLGAVF+VCL+LT S
Sbjct: 1070 MKAARDFSSKLSDSLKMEIFPYSVFYIFFEQYLDIWRTALINISIGLGAVFIVCLILTSS 1129

Query: 2999 IWVSTIILAVLVMIVIDMLGLMAILGIQLNAISVVNLVMSIGIAVEFCVHITHAFLLSSG 3178
            IW+S IIL VL MI+IDMLG+MAIL IQLNAISVVNLVMSIGIAVEFCVH+ HAFL++SG
Sbjct: 1130 IWISAIILLVLTMIIIDMLGVMAILDIQLNAISVVNLVMSIGIAVEFCVHVMHAFLVNSG 1189

Query: 3179 DRETRMKMALSTMGASVFSGITLTKLVGV 3265
            DR +R K A+STMGASVFSGITLTKLVGV
Sbjct: 1190 DRGSRTKEAVSTMGASVFSGITLTKLVGV 1218


>ref|XP_019702346.1| PREDICTED: Niemann-Pick C1 protein-like [Elaeis guineensis]
          Length = 1294

 Score =  865 bits (2235), Expect = 0.0
 Identities = 440/689 (63%), Positives = 518/689 (75%), Gaps = 7/689 (1%)
 Frame = +1

Query: 1    QQAIPLLVSCPACLRNFLNLFCELSCSPDQSLFINVTSVKKVNDSMTVDMIDYFITPYFG 180
            QQAIP LV CPACLRNFLNLFCELSCSP+QSLFINVTSV KVND++TVD ID+++T  + 
Sbjct: 110  QQAIPFLVGCPACLRNFLNLFCELSCSPNQSLFINVTSVMKVNDTLTVDGIDFYVTSQYV 169

Query: 181  EQLFNSCKDVKFGTLNTRAMDFVGGGAQNYTEWFAFLGHRANLSMPGSPYAIAFQSIISD 360
            E+LFNSCKDVKFGT+NTRAMDFVG GAQNY EW AF+GHRANLS PGSPYAIAFQ+ ++D
Sbjct: 170  EELFNSCKDVKFGTMNTRAMDFVGAGAQNYKEWLAFIGHRANLSEPGSPYAIAFQTTLND 229

Query: 361  LSGVRPLNATVYSCGDTSLGCSCGDCPSSALCVGSLQPAPHVKRSCSVKIASLKVKCLDF 540
               ++P+N TVYSCGD+SLGCSCGDCPSS++C  S  PAP  K++C+++I SLKVKCLDF
Sbjct: 230  SVRIKPMNVTVYSCGDSSLGCSCGDCPSSSVCFDSASPAPQEKQACAIRIGSLKVKCLDF 289

Query: 541  SLVIVYLFLLPAFLLWGSWYQKKKADP--SRTEPFFNANGGN---SSDKQENRSP--QIS 699
            SL ++Y  L+ AF +WG W  +K+     SRT+P  N  G N   S +KQE  +   Q S
Sbjct: 290  SLAMLYFLLVSAFSVWG-WLNRKQDRTCLSRTKPSVNVKGENELHSVNKQEISAQLTQAS 348

Query: 700  EAVPSVIKANRPSVVQLYLSSFFRKYGNFISRHPTXXXXXXXXXXXXXXXXXIRFKVETR 879
            E    V+K  RPSVVQ ++S+FFR YG+F+SR+P                  IRFKVETR
Sbjct: 349  EEASPVVKMLRPSVVQGHISNFFRIYGSFVSRNPNLVLCLSLAVPLLLCLGLIRFKVETR 408

Query: 880  PEKLWVGPGSKAAKEKLYFDSHLAPFYRIEQFILANISASNGENPPNIVTEENVKLLFQI 1059
            PEKLWVGPGS+A +EK +FDSHLAPFYRIEQ ILA +  S  + PP+IVT++N+KLLF+I
Sbjct: 409  PEKLWVGPGSRAVEEKQFFDSHLAPFYRIEQLILATVPVSKRDKPPSIVTDKNIKLLFEI 468

Query: 1060 QKKVDDLHANYSGSVVSLPDICLKPLGNDCATQSILQYFQMDPQNYDAYGGLAHLQYCFE 1239
            QKK+D L AN+SGS+VSL DICLKPLG+DCATQS+LQYF+MDP+NYD YGG+ H +YCF+
Sbjct: 469  QKKIDGLRANFSGSMVSLTDICLKPLGDDCATQSVLQYFKMDPENYDGYGGVNHAEYCFQ 528

Query: 1240 HFSSEKSCLSAFSAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDKTSSEYRNAVAWE 1419
            H+SS ++CLSAF AP DP+TALGGFS +NYSEASAFV+TYPVNN +DKT  E   AVAWE
Sbjct: 529  HYSSAETCLSAFQAPQDPATALGGFSRSNYSEASAFVVTYPVNNEIDKTGKENGKAVAWE 588

Query: 1420 KAFVQLMKDEIIPMVXXXXXXXXXXXXXXXXXXXKRESTADAITIFISYLVMFAYISVTL 1599
            KAF+ L+K+E+ PMV                   KRESTAD ITI ISYLVMFAYIS TL
Sbjct: 589  KAFIHLVKEELGPMVQLQNLTLSFSSESSIQEELKRESTADVITILISYLVMFAYISFTL 648

Query: 1600 GNRHHLSSIFXXXXXXXXXXXXXXXXXXXXXXXXFYSAIGVKSTLIIMEVIPFLVLAVGV 1779
            G+   +SS                          F+SAIGVKSTLIIMEVIPFLVLAVGV
Sbjct: 649  GDTPRMSSFLVSSKVLLGLSGVVLVMLSVLGSIGFFSAIGVKSTLIIMEVIPFLVLAVGV 708

Query: 1780 DNMCILVHTIKRQPLELLLEERISSALADVGPSITLASLSEVLAFAVGSFIPMPACRVFS 1959
            DNMCILVH +KRQPLEL LE RIS+AL +VGPSITLASLSEVLAFAVGSFIPMPACRVFS
Sbjct: 709  DNMCILVHAVKRQPLELPLEGRISNALMEVGPSITLASLSEVLAFAVGSFIPMPACRVFS 768

Query: 1960 MXXXXXXXXXXXXQVTAFVSLIIFDFLRA 2046
            M            QVTAFV+LIIFDFLRA
Sbjct: 769  MFAALAVLLDFLLQVTAFVALIIFDFLRA 797



 Score =  629 bits (1623), Expect = 0.0
 Identities = 308/389 (79%), Positives = 341/389 (87%)
 Frame = +2

Query: 2099 LRGVKIIVILVFSGFAFASIALCTRVQPGLEQKIVLPRDSYLQNYFDDLAKYLRVGPPLY 2278
            L GVKI+VI VF GFA ASIALCTR+QPGLEQK+VLP+DSYLQ+YFDDLAKYLRVGPPLY
Sbjct: 842  LLGVKILVIAVFVGFALASIALCTRLQPGLEQKVVLPQDSYLQDYFDDLAKYLRVGPPLY 901

Query: 2279 FVVKDFNYSLESRNTNQICSISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWL 2458
            FVVKDFNYSLESR+TNQICSISQCDSNSLLNEI KASL+P SSYIAKPAASWLDDFLIWL
Sbjct: 902  FVVKDFNYSLESRHTNQICSISQCDSNSLLNEIAKASLIPDSSYIAKPAASWLDDFLIWL 961

Query: 2459 SPEAFSCCRKFLNGSYXXXXXXXXXXXXXXGLCNMGTTCKDCTTCYRYSDLHDGRPSTMD 2638
            SPEAFSCCRKF+NGSY              G C MG  CKDCTTC+RYS LH+GRPST+ 
Sbjct: 962  SPEAFSCCRKFVNGSYCPPDDQPPCCQPDEGSCGMGEICKDCTTCFRYSQLHNGRPSTVQ 1021

Query: 2639 FKVKLPWFLNALPSSNCAKGGKGAYTSSVDLSGYESGIIQASSFRTYHTPLNRQIDYVNS 2818
            FK KLPWFLNALPSS+CAKGGKGAYT+SVDL+GYESGIIQA+SFRTYHTPLN+Q DYVNS
Sbjct: 1022 FKQKLPWFLNALPSSDCAKGGKGAYTTSVDLTGYESGIIQAASFRTYHTPLNKQSDYVNS 1081

Query: 2819 MKAALDFXXXXXXXXXMEIFPYSVFYIFFEQYLDIWRTALINISIGLGAVFVVCLVLTGS 2998
            M+AA DF         M+IFPYSVFY+FFEQYLDIW+TALI+ISIGLGA+F+VCLV+T S
Sbjct: 1082 MRAAQDFSSKISDSLKMQIFPYSVFYVFFEQYLDIWKTALIDISIGLGAIFIVCLVITCS 1141

Query: 2999 IWVSTIILAVLVMIVIDMLGLMAILGIQLNAISVVNLVMSIGIAVEFCVHITHAFLLSSG 3178
            +W S II  VL MI++DM+G+MAIL IQLNA+SVVNLVMSIGIAVEFCVHITHAF  S+G
Sbjct: 1142 LWTSAIIFIVLAMILVDMMGVMAILEIQLNAVSVVNLVMSIGIAVEFCVHITHAFSASNG 1201

Query: 3179 DRETRMKMALSTMGASVFSGITLTKLVGV 3265
            DR+TR+K ALSTMGASVFSGITLTKLVGV
Sbjct: 1202 DRQTRVKEALSTMGASVFSGITLTKLVGV 1230


>ref|XP_020084535.1| Niemann-Pick C1 protein-like [Ananas comosus]
          Length = 1300

 Score =  851 bits (2199), Expect = 0.0
 Identities = 440/690 (63%), Positives = 512/690 (74%), Gaps = 8/690 (1%)
 Frame = +1

Query: 1    QQAIPLLVSCPACLRNFLNLFCELSCSPDQSLFINVTSVKKVNDSMTVDMIDYFITPYFG 180
            QQAIP LV CPACLRNFLN+FCELSCSP+QSLFINVTS+ +VN++MTVD ID+F+T  +G
Sbjct: 114  QQAIPFLVGCPACLRNFLNIFCELSCSPNQSLFINVTSIAEVNNTMTVDGIDFFVTSEYG 173

Query: 181  EQLFNSCKDVKFGTLNTRAMDFVGGGAQNYTEWFAFLGHRANLSMPGSPYAIAFQSIISD 360
            E+L+NSCKDVKFGT+NTR+MDF+GG AQNYTEWFAFLG +ANL+ PGSPYA++F+S ISD
Sbjct: 174  EELYNSCKDVKFGTMNTRSMDFIGGAAQNYTEWFAFLGRQANLNEPGSPYAVSFRSDISD 233

Query: 361  LSGVRPLNATVYSCGDTSLGCSCGDCPSSALCVGSLQPAPHVKRSCSVKIASLKVKCLDF 540
             SG++PLN TVYSCGD SLGCSCGDCPSS++C+ +   A   KRSCS K+ SLKVKCL+F
Sbjct: 234  SSGMKPLNITVYSCGDHSLGCSCGDCPSSSVCMNNAPSASRGKRSCSFKMGSLKVKCLEF 293

Query: 541  SLVIVYLFLLPAFLLWGSWYQKKKADP--SRTEPFFNANGGN-----SSDKQENRSPQIS 699
            SL IVY  LL AFL W S ++K++     SRTEP  N    N     S ++   R  QI+
Sbjct: 294  SLAIVYFVLLAAFLTWVSLHRKRERVGLFSRTEPLQNVQDQNQLHSVSKEELSGRPLQIT 353

Query: 700  EAVPSVIKANRPSVVQLYLSSFFRKYGNFISRHPTXXXXXXXXXXXXXXXXXIRFKVETR 879
            E VP V +  RPSVVQ Y++SFFRKYG F++R+P                  IRFKVETR
Sbjct: 354  EEVPLVAETLRPSVVQSYMTSFFRKYGTFVARNPILVLCLSLAVPLLLCIGLIRFKVETR 413

Query: 880  PEKLWVGPGSKAAKEKLYFDSHLAPFYRIEQFILANISASNGENPPNIVTEENVKLLFQI 1059
            PEKLWVGPGSKAA+EK YFDSHLAPFYRIEQ I+A I AS   + P IVT  N++LLF++
Sbjct: 414  PEKLWVGPGSKAAEEKQYFDSHLAPFYRIEQLIVATIPASRTSSSPTIVTGNNIQLLFEV 473

Query: 1060 QKKVDDLHANYSGSVVSLPDICLKPLGNDCATQSILQYFQMDPQNYDAYGGLAHLQYCFE 1239
            QKKVD L ANYSG++VSL DIC KPLG DCATQS+LQYFQMDPQ Y+   G+ H +YCF+
Sbjct: 474  QKKVDGLRANYSGNMVSLSDICFKPLGADCATQSVLQYFQMDPQKYNDL-GIDHAKYCFQ 532

Query: 1240 HFSSEKSCLSAFSAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDKTSSEYRNAVAWE 1419
            HFSS++SCLSAF APLDPSTALGGFSGNNYSEASAFVITYPVNN +DKT  E   AVAWE
Sbjct: 533  HFSSDESCLSAFQAPLDPSTALGGFSGNNYSEASAFVITYPVNNKVDKTGEENGQAVAWE 592

Query: 1420 KAFVQLMKDEIIPMVXXXXXXXXXXXXXXXXXXXKRESTADAITIFISYLVMFAYISVTL 1599
            +AF+ LMK+EI+PM+                   KRESTADAITI ISYLVMFAYIS  L
Sbjct: 593  EAFIHLMKEEIMPMIQMQNLTLAFSSESSIQEELKRESTADAITILISYLVMFAYISFAL 652

Query: 1600 GNRHHLSSIF-XXXXXXXXXXXXXXXXXXXXXXXXFYSAIGVKSTLIIMEVIPFLVLAVG 1776
            G+    SS F                         F++AIGVKSTLIIMEVIPFLVLAVG
Sbjct: 653  GDSFRCSSSFIISSKVLLGLSGVVLVLLSVLGSIGFFTAIGVKSTLIIMEVIPFLVLAVG 712

Query: 1777 VDNMCILVHTIKRQPLELLLEERISSALADVGPSITLASLSEVLAFAVGSFIPMPACRVF 1956
            VDNMCILVH +KRQPL L LE RIS+AL +VGPSITLASLSE LAFAV +F PMPACRVF
Sbjct: 713  VDNMCILVHAVKRQPLALSLEGRISNALVEVGPSITLASLSEFLAFAVSTFTPMPACRVF 772

Query: 1957 SMXXXXXXXXXXXXQVTAFVSLIIFDFLRA 2046
            SM            QVTAFV+LI+FDF+RA
Sbjct: 773  SMFAALAVLLDFVLQVTAFVALIVFDFIRA 802



 Score =  614 bits (1583), Expect = 0.0
 Identities = 303/389 (77%), Positives = 333/389 (85%)
 Frame = +2

Query: 2099 LRGVKIIVILVFSGFAFASIALCTRVQPGLEQKIVLPRDSYLQNYFDDLAKYLRVGPPLY 2278
            LRGVK+IVI VF GFAF SI L TR+QPGLEQKIVLPR+SYLQ+YFDDLAKYLR+GPPLY
Sbjct: 847  LRGVKVIVIAVFVGFAFTSIVLSTRLQPGLEQKIVLPRNSYLQDYFDDLAKYLRIGPPLY 906

Query: 2279 FVVKDFNYSLESRNTNQICSISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWL 2458
            FVVKDFNYSLES  TNQICSISQC+SNSLLNEI KASLVP SSYIAKPAASWLDDFLIWL
Sbjct: 907  FVVKDFNYSLESSQTNQICSISQCNSNSLLNEIAKASLVPESSYIAKPAASWLDDFLIWL 966

Query: 2459 SPEAFSCCRKFLNGSYXXXXXXXXXXXXXXGLCNMGTTCKDCTTCYRYSDLHDGRPSTMD 2638
            SPEAFSCCR+F+NGSY              G C +   CKDCTTC+R+SDLHDGRPS   
Sbjct: 967  SPEAFSCCREFVNGSYCPPDDQPPCCQPSQGSCGVTGKCKDCTTCFRHSDLHDGRPSIAQ 1026

Query: 2639 FKVKLPWFLNALPSSNCAKGGKGAYTSSVDLSGYESGIIQASSFRTYHTPLNRQIDYVNS 2818
            FK KLPWFLNALPSS+CAKGGKGAYT++V+L+GYE GIIQAS+FRTYHTPLN+Q DYVNS
Sbjct: 1027 FKEKLPWFLNALPSSDCAKGGKGAYTTNVNLTGYERGIIQASAFRTYHTPLNKQTDYVNS 1086

Query: 2819 MKAALDFXXXXXXXXXMEIFPYSVFYIFFEQYLDIWRTALINISIGLGAVFVVCLVLTGS 2998
            MKAA DF         M+IFPYSVFYIFFEQYLDIW+T+LINISIGLGAVF+VCLV+TGS
Sbjct: 1087 MKAARDFSSKISDSLQMQIFPYSVFYIFFEQYLDIWKTSLINISIGLGAVFMVCLVVTGS 1146

Query: 2999 IWVSTIILAVLVMIVIDMLGLMAILGIQLNAISVVNLVMSIGIAVEFCVHITHAFLLSSG 3178
            +W S IIL V+ MI++DM+G+M IL IQLNAISVVNLVMSIGIAVEFCVHITHAF +S G
Sbjct: 1147 LWASAIILLVIAMIILDMMGVMGILDIQLNAISVVNLVMSIGIAVEFCVHITHAFSISRG 1206

Query: 3179 DRETRMKMALSTMGASVFSGITLTKLVGV 3265
            DR TR K AL TMGASVFSGITLTKLVGV
Sbjct: 1207 DRNTRAKEALCTMGASVFSGITLTKLVGV 1235


>ref|XP_010918252.2| PREDICTED: Niemann-Pick C1 protein-like isoform X3 [Elaeis
            guineensis]
          Length = 1294

 Score =  850 bits (2196), Expect = 0.0
 Identities = 435/688 (63%), Positives = 510/688 (74%), Gaps = 6/688 (0%)
 Frame = +1

Query: 1    QQAIPLLVSCPACLRNFLNLFCELSCSPDQSLFINVTSVKKVNDSMTVDMIDYFITPYFG 180
            QQ IP LV CPACLRNFLNLFCEL+CSP+QSLFINV+SV KV   + VD ID++IT  + 
Sbjct: 111  QQVIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVSSVTKVXXXLRVDGIDFYITSVYV 170

Query: 181  EQLFNSCKDVKFGTLNTRAMDFVGGGAQNYTEWFAFLGHRANLSMPGSPYAIAFQSIISD 360
            E+LFNSCKDVKFGT+NTRAMDFVG GAQNY EW AF+GH+AN + PGSPYAIAFQ I  D
Sbjct: 171  EELFNSCKDVKFGTMNTRAMDFVGAGAQNYKEWLAFIGHQANPNEPGSPYAIAFQ-IDVD 229

Query: 361  LSGVRPLNATVYSCGDTSLGCSCGDCPSSALCVGSLQPAPHVKRSCSVKIASLKVKCLDF 540
             SG++P+N TVYSCGD SLGCSCGDCPSS++C  S  PAP  K++C+++I SLKVKCLDF
Sbjct: 230  SSGMKPMNVTVYSCGDPSLGCSCGDCPSSSVCSDSASPAPREKQACAIRIGSLKVKCLDF 289

Query: 541  SLVIVYLFLLPAFLLWGSWYQKK-KADPSRTEPFFNANGGN---SSDKQE--NRSPQISE 702
            SL I+YL  + A L WG  ++K+ +  PSRT+ F N    N   S +KQE   +  Q+SE
Sbjct: 290  SLAILYLLTISAILAWGLLHRKQERTGPSRTKLFLNVKDENELHSVNKQEISTQPNQVSE 349

Query: 703  AVPSVIKANRPSVVQLYLSSFFRKYGNFISRHPTXXXXXXXXXXXXXXXXXIRFKVETRP 882
             VP+V+    PSVVQ Y+ +FFR YG+F+SR+PT                 I FKVET+P
Sbjct: 350  EVPAVVTMLHPSVVQGYILNFFRIYGSFVSRNPTLVLCLSLAVPLLLCIGLIHFKVETQP 409

Query: 883  EKLWVGPGSKAAKEKLYFDSHLAPFYRIEQFILANISASNGENPPNIVTEENVKLLFQIQ 1062
            EKLWVGP SKAA+EK YFDSHLAPFYRIEQ ILA +  S  E PP+IVTE+N+KLLF+IQ
Sbjct: 410  EKLWVGPRSKAAEEKQYFDSHLAPFYRIEQLILATVPVSKHEKPPSIVTEKNIKLLFEIQ 469

Query: 1063 KKVDDLHANYSGSVVSLPDICLKPLGNDCATQSILQYFQMDPQNYDAYGGLAHLQYCFEH 1242
            KK+D L AN+SGS V L DICLKPLG DCATQS+LQYF+MDP+NYD +GG+ H +YCF+H
Sbjct: 470  KKIDGLRANFSGSTVFLTDICLKPLGEDCATQSVLQYFKMDPENYDGFGGVDHAEYCFQH 529

Query: 1243 FSSEKSCLSAFSAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDKTSSEYRNAVAWEK 1422
            +SS ++CLSAF APLDP+TALGGF+G+NYSEASAFVITYPVNN  DK   E   AVAWEK
Sbjct: 530  YSSAETCLSAFQAPLDPATALGGFTGSNYSEASAFVITYPVNNEADKNGKENGKAVAWEK 589

Query: 1423 AFVQLMKDEIIPMVXXXXXXXXXXXXXXXXXXXKRESTADAITIFISYLVMFAYISVTLG 1602
            AF+ L+K+E+ PMV                   KRESTAD ITI +SYLVMFAYIS TLG
Sbjct: 590  AFIHLVKEELRPMVQLQNLTLSFSSESSVQEELKRESTADVITIVVSYLVMFAYISFTLG 649

Query: 1603 NRHHLSSIFXXXXXXXXXXXXXXXXXXXXXXXXFYSAIGVKSTLIIMEVIPFLVLAVGVD 1782
            +  H+SS                          F+SAIGVKSTLIIMEVIPFLVLAVGVD
Sbjct: 650  DSPHMSSFIVSSKVLLGLSGVVLVMLSVLGSIGFFSAIGVKSTLIIMEVIPFLVLAVGVD 709

Query: 1783 NMCILVHTIKRQPLELLLEERISSALADVGPSITLASLSEVLAFAVGSFIPMPACRVFSM 1962
            NMCILVH +KRQ LEL LEERI++AL +VGPSITLASLSE+LAFAVGSFIPMPACRVFSM
Sbjct: 710  NMCILVHAVKRQSLELPLEERITNALVEVGPSITLASLSEILAFAVGSFIPMPACRVFSM 769

Query: 1963 XXXXXXXXXXXXQVTAFVSLIIFDFLRA 2046
                        QVTAFV+LIIFDFLRA
Sbjct: 770  FAALAVLLDFLLQVTAFVALIIFDFLRA 797



 Score =  627 bits (1617), Expect = 0.0
 Identities = 308/389 (79%), Positives = 342/389 (87%)
 Frame = +2

Query: 2099 LRGVKIIVILVFSGFAFASIALCTRVQPGLEQKIVLPRDSYLQNYFDDLAKYLRVGPPLY 2278
            L GVKIIVI +F GFA ASIALCTR+QPGLEQK+VLPRDSYLQ+YFDDLAKYLRVGPPLY
Sbjct: 842  LLGVKIIVIALFVGFALASIALCTRLQPGLEQKVVLPRDSYLQDYFDDLAKYLRVGPPLY 901

Query: 2279 FVVKDFNYSLESRNTNQICSISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWL 2458
            FVVKDFNYSLES+ TN+ICSIS+CDSNSLLNEI KASL+P SSYIAKPAASWLDDFLIWL
Sbjct: 902  FVVKDFNYSLESKQTNKICSISRCDSNSLLNEIAKASLIPESSYIAKPAASWLDDFLIWL 961

Query: 2459 SPEAFSCCRKFLNGSYXXXXXXXXXXXXXXGLCNMGTTCKDCTTCYRYSDLHDGRPSTMD 2638
            SPEAFSCCRKF+NGSY              G C +G  CKDCTTC+RYS+LHDGRPS + 
Sbjct: 962  SPEAFSCCRKFVNGSYCPPDDQPPCCQPDEGSCGVGGICKDCTTCFRYSELHDGRPSMVQ 1021

Query: 2639 FKVKLPWFLNALPSSNCAKGGKGAYTSSVDLSGYESGIIQASSFRTYHTPLNRQIDYVNS 2818
            FK KLPWFLNALPSS+CAKGGKGAYT+SVDL+GYESGIIQA+SFRTYHTPLN+Q DYVNS
Sbjct: 1022 FKEKLPWFLNALPSSDCAKGGKGAYTTSVDLTGYESGIIQAASFRTYHTPLNKQSDYVNS 1081

Query: 2819 MKAALDFXXXXXXXXXMEIFPYSVFYIFFEQYLDIWRTALINISIGLGAVFVVCLVLTGS 2998
            M+AA DF         M+IFPYS+FYIFFEQYLDIW+TAL +ISIGLGAVF+VCLV+T S
Sbjct: 1082 MRAARDFSSKISDSLKMQIFPYSMFYIFFEQYLDIWKTALTDISIGLGAVFIVCLVITCS 1141

Query: 2999 IWVSTIILAVLVMIVIDMLGLMAILGIQLNAISVVNLVMSIGIAVEFCVHITHAFLLSSG 3178
            +W STIIL VL MIV+DM+G+MAIL IQLNA+SVVNLVMSIGIAVEFCVHITHAF +S+G
Sbjct: 1142 LWTSTIILIVLGMIVVDMMGVMAILEIQLNAVSVVNLVMSIGIAVEFCVHITHAFSVSNG 1201

Query: 3179 DRETRMKMALSTMGASVFSGITLTKLVGV 3265
            DR+TR+K ALSTMGASVFSGITLTKLVGV
Sbjct: 1202 DRQTRVKKALSTMGASVFSGITLTKLVGV 1230


>gb|POF00322.1| niemann-pick c1 protein [Quercus suber]
          Length = 1290

 Score =  844 bits (2180), Expect = 0.0
 Identities = 421/688 (61%), Positives = 510/688 (74%), Gaps = 6/688 (0%)
 Frame = +1

Query: 1    QQAIPLLVSCPACLRNFLNLFCELSCSPDQSLFINVTSVKKVNDSMTVDMIDYFITPYFG 180
            QQAIP LV CPACLRNFLNLFCEL+CSP+QSLFINVT++ KVN++MTVD ID+++T  FG
Sbjct: 109  QQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTAISKVNNNMTVDGIDFYVTDSFG 168

Query: 181  EQLFNSCKDVKFGTLNTRAMDFVGGGAQNYTEWFAFLGHRANLSMPGSPYAIAFQSIISD 360
            E L++SCKDVKFGT+N+RA+ F+G GAQN+ EW+AF+G +A   MPGSPYAI F S  ++
Sbjct: 169  EGLYDSCKDVKFGTMNSRAIQFIGAGAQNFKEWYAFIGRQAEPHMPGSPYAIKFLSNATE 228

Query: 361  LSGVRPLNATVYSCGDTSLGCSCGDCPSSALCVGSLQPAPHVKRSCSVKIASLKVKCLDF 540
             SG++P+N ++YSCGD SLGCSCGDCPSS +C  +  PA H   SCSV++ SLK KC+DF
Sbjct: 229  SSGMKPMNVSIYSCGDISLGCSCGDCPSSPVCTNTAPPAHHKAGSCSVRVGSLKAKCIDF 288

Query: 541  SLVIVYLFLLPAFLLWGSWYQKKKADP-SRTEPFFNANGGN-----SSDKQENRSPQISE 702
            +L I+Y+ L+  FL WG +++ ++ +P SRT+PF N N G      +  K EN   Q+ E
Sbjct: 289  ALAILYIILVSMFLGWGLFHRTRERNPRSRTKPFLNVNDGGQLHSVNRQKDENLPMQMLE 348

Query: 703  AVPSVIKANRPSVVQLYLSSFFRKYGNFISRHPTXXXXXXXXXXXXXXXXXIRFKVETRP 882
              P +    + SVVQ Y+S+F+R+YG +++R+PT                 +RFKVETRP
Sbjct: 349  DHPQIRNGVQLSVVQGYMSNFYRRYGTWVARNPTLVLCSSLAMVLVLCLGLVRFKVETRP 408

Query: 883  EKLWVGPGSKAAKEKLYFDSHLAPFYRIEQFILANISASNGENPPNIVTEENVKLLFQIQ 1062
            EKLWVGPGSKAA+EK +FDSHLAPFYRIEQ ILA    +     P+IVTE N+KLLF+IQ
Sbjct: 409  EKLWVGPGSKAAEEKQFFDSHLAPFYRIEQLILATTPDAVDGKLPSIVTENNIKLLFEIQ 468

Query: 1063 KKVDDLHANYSGSVVSLPDICLKPLGNDCATQSILQYFQMDPQNYDAYGGLAHLQYCFEH 1242
            KKVD +HANY GS++SL DIC+KPL  DCATQS+LQYF+MDP+NYD YGG+ HL+YCFEH
Sbjct: 469  KKVDRIHANYLGSMISLNDICMKPLDQDCATQSVLQYFKMDPENYDNYGGVEHLKYCFEH 528

Query: 1243 FSSEKSCLSAFSAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDKTSSEYRNAVAWEK 1422
            +SS   C+SAF  PLDPSTALGGF GNNYSEASAF+ITYPVNN +DK  +E + AVAWEK
Sbjct: 529  YSSADKCMSAFKGPLDPSTALGGFPGNNYSEASAFIITYPVNNAIDKEGNETQKAVAWEK 588

Query: 1423 AFVQLMKDEIIPMVXXXXXXXXXXXXXXXXXXXKRESTADAITIFISYLVMFAYISVTLG 1602
            AF+QL+KDE++PMV                   KRESTADAITI ISYLVMFAYIS+TLG
Sbjct: 589  AFIQLVKDELLPMVQSKNVTVSFSSESSIEEELKRESTADAITIVISYLVMFAYISLTLG 648

Query: 1603 NRHHLSSIFXXXXXXXXXXXXXXXXXXXXXXXXFYSAIGVKSTLIIMEVIPFLVLAVGVD 1782
            +   LSS +                        F+SAIGVKSTLIIMEVIPFLVLAVGVD
Sbjct: 649  DSPRLSSFYISSKVLLGLCGVMLVMLSVLASVGFFSAIGVKSTLIIMEVIPFLVLAVGVD 708

Query: 1783 NMCILVHTIKRQPLELLLEERISSALADVGPSITLASLSEVLAFAVGSFIPMPACRVFSM 1962
            NMCILVH +KRQPLEL LE RIS+AL +VGPSITLASLSEVLAFAVGSFIPMPACRVFSM
Sbjct: 709  NMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSM 768

Query: 1963 XXXXXXXXXXXXQVTAFVSLIIFDFLRA 2046
                        QVTAFV+LI+FDFLRA
Sbjct: 769  FAALAVLLDFLLQVTAFVALIVFDFLRA 796



 Score =  573 bits (1477), Expect = 0.0
 Identities = 274/389 (70%), Positives = 327/389 (84%)
 Frame = +2

Query: 2099 LRGVKIIVILVFSGFAFASIALCTRVQPGLEQKIVLPRDSYLQNYFDDLAKYLRVGPPLY 2278
            L GVKI+VI +F G A ASIALCTR++PGLEQKIVLPRDSYLQ YF+++++YLR+GPPLY
Sbjct: 842  LWGVKIVVISLFLGCALASIALCTRIEPGLEQKIVLPRDSYLQGYFNNVSEYLRIGPPLY 901

Query: 2279 FVVKDFNYSLESRNTNQICSISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWL 2458
            FVVK++NYS ESR+TNQ+CSISQC+S+SLLNEI +ASL P SSYIA PAASWLDDFL+W+
Sbjct: 902  FVVKNYNYSSESRHTNQLCSISQCESDSLLNEIARASLTPESSYIAMPAASWLDDFLVWM 961

Query: 2459 SPEAFSCCRKFLNGSYXXXXXXXXXXXXXXGLCNMGTTCKDCTTCYRYSDLHDGRPSTMD 2638
            SPEAF CCRKF NGSY                C +   CKDCTTC+R+SDL + RPST+ 
Sbjct: 962  SPEAFGCCRKFTNGSYCPPDDQPPCCSSNDVACGVNGVCKDCTTCFRHSDLQNDRPSTLQ 1021

Query: 2639 FKVKLPWFLNALPSSNCAKGGKGAYTSSVDLSGYESGIIQASSFRTYHTPLNRQIDYVNS 2818
            FK KLPWFL+ALPS++CAKGG GAYT+SV+L GY++GIIQASSFRTYHTPLN+Q+DYVNS
Sbjct: 1022 FKEKLPWFLDALPSADCAKGGHGAYTTSVELEGYDNGIIQASSFRTYHTPLNKQVDYVNS 1081

Query: 2819 MKAALDFXXXXXXXXXMEIFPYSVFYIFFEQYLDIWRTALINISIGLGAVFVVCLVLTGS 2998
            M+AA +F         +EIFPYSVFY+FFEQYLDIWRTALIN++I +GAVF+VCL++T S
Sbjct: 1082 MRAAREFSSKVSDSLKIEIFPYSVFYMFFEQYLDIWRTALINLAIAIGAVFIVCLIITSS 1141

Query: 2999 IWVSTIILAVLVMIVIDMLGLMAILGIQLNAISVVNLVMSIGIAVEFCVHITHAFLLSSG 3178
             W S IIL VL MIV+D++G+MAIL IQLNA+SVVNLVMS+GIAVEFCVH+THAF +SSG
Sbjct: 1142 FWSSAIILLVLAMIVVDLMGVMAILEIQLNAVSVVNLVMSVGIAVEFCVHMTHAFSVSSG 1201

Query: 3179 DRETRMKMALSTMGASVFSGITLTKLVGV 3265
            D++ R K AL TMGASVFSGITLTKLVGV
Sbjct: 1202 DKDQRTKEALGTMGASVFSGITLTKLVGV 1230


>ref|XP_023920396.1| Niemann-Pick C1 protein-like [Quercus suber]
          Length = 1304

 Score =  844 bits (2180), Expect = 0.0
 Identities = 421/688 (61%), Positives = 510/688 (74%), Gaps = 6/688 (0%)
 Frame = +1

Query: 1    QQAIPLLVSCPACLRNFLNLFCELSCSPDQSLFINVTSVKKVNDSMTVDMIDYFITPYFG 180
            QQAIP LV CPACLRNFLNLFCEL+CSP+QSLFINVT++ KVN++MTVD ID+++T  FG
Sbjct: 123  QQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTAISKVNNNMTVDGIDFYVTDSFG 182

Query: 181  EQLFNSCKDVKFGTLNTRAMDFVGGGAQNYTEWFAFLGHRANLSMPGSPYAIAFQSIISD 360
            E L++SCKDVKFGT+N+RA+ F+G GAQN+ EW+AF+G +A   MPGSPYAI F S  ++
Sbjct: 183  EGLYDSCKDVKFGTMNSRAIQFIGAGAQNFKEWYAFIGRQAEPHMPGSPYAIKFLSNATE 242

Query: 361  LSGVRPLNATVYSCGDTSLGCSCGDCPSSALCVGSLQPAPHVKRSCSVKIASLKVKCLDF 540
             SG++P+N ++YSCGD SLGCSCGDCPSS +C  +  PA H   SCSV++ SLK KC+DF
Sbjct: 243  SSGMKPMNVSIYSCGDISLGCSCGDCPSSPVCTNTAPPAHHKAGSCSVRVGSLKAKCIDF 302

Query: 541  SLVIVYLFLLPAFLLWGSWYQKKKADP-SRTEPFFNANGGN-----SSDKQENRSPQISE 702
            +L I+Y+ L+  FL WG +++ ++ +P SRT+PF N N G      +  K EN   Q+ E
Sbjct: 303  ALAILYIILVSMFLGWGLFHRTRERNPRSRTKPFLNVNDGGQLHSVNRQKDENLPMQMLE 362

Query: 703  AVPSVIKANRPSVVQLYLSSFFRKYGNFISRHPTXXXXXXXXXXXXXXXXXIRFKVETRP 882
              P +    + SVVQ Y+S+F+R+YG +++R+PT                 +RFKVETRP
Sbjct: 363  DHPQIRNGVQLSVVQGYMSNFYRRYGTWVARNPTLVLCSSLAMVLVLCLGLVRFKVETRP 422

Query: 883  EKLWVGPGSKAAKEKLYFDSHLAPFYRIEQFILANISASNGENPPNIVTEENVKLLFQIQ 1062
            EKLWVGPGSKAA+EK +FDSHLAPFYRIEQ ILA    +     P+IVTE N+KLLF+IQ
Sbjct: 423  EKLWVGPGSKAAEEKQFFDSHLAPFYRIEQLILATTPDAVDGKLPSIVTENNIKLLFEIQ 482

Query: 1063 KKVDDLHANYSGSVVSLPDICLKPLGNDCATQSILQYFQMDPQNYDAYGGLAHLQYCFEH 1242
            KKVD +HANY GS++SL DIC+KPL  DCATQS+LQYF+MDP+NYD YGG+ HL+YCFEH
Sbjct: 483  KKVDRIHANYLGSMISLNDICMKPLDQDCATQSVLQYFKMDPENYDNYGGVEHLKYCFEH 542

Query: 1243 FSSEKSCLSAFSAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDKTSSEYRNAVAWEK 1422
            +SS   C+SAF  PLDPSTALGGF GNNYSEASAF+ITYPVNN +DK  +E + AVAWEK
Sbjct: 543  YSSADKCMSAFKGPLDPSTALGGFPGNNYSEASAFIITYPVNNAIDKEGNETQKAVAWEK 602

Query: 1423 AFVQLMKDEIIPMVXXXXXXXXXXXXXXXXXXXKRESTADAITIFISYLVMFAYISVTLG 1602
            AF+QL+KDE++PMV                   KRESTADAITI ISYLVMFAYIS+TLG
Sbjct: 603  AFIQLVKDELLPMVQSKNVTVSFSSESSIEEELKRESTADAITIVISYLVMFAYISLTLG 662

Query: 1603 NRHHLSSIFXXXXXXXXXXXXXXXXXXXXXXXXFYSAIGVKSTLIIMEVIPFLVLAVGVD 1782
            +   LSS +                        F+SAIGVKSTLIIMEVIPFLVLAVGVD
Sbjct: 663  DSPRLSSFYISSKVLLGLCGVMLVMLSVLASVGFFSAIGVKSTLIIMEVIPFLVLAVGVD 722

Query: 1783 NMCILVHTIKRQPLELLLEERISSALADVGPSITLASLSEVLAFAVGSFIPMPACRVFSM 1962
            NMCILVH +KRQPLEL LE RIS+AL +VGPSITLASLSEVLAFAVGSFIPMPACRVFSM
Sbjct: 723  NMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSM 782

Query: 1963 XXXXXXXXXXXXQVTAFVSLIIFDFLRA 2046
                        QVTAFV+LI+FDFLRA
Sbjct: 783  FAALAVLLDFLLQVTAFVALIVFDFLRA 810



 Score =  573 bits (1477), Expect = 0.0
 Identities = 274/389 (70%), Positives = 327/389 (84%)
 Frame = +2

Query: 2099 LRGVKIIVILVFSGFAFASIALCTRVQPGLEQKIVLPRDSYLQNYFDDLAKYLRVGPPLY 2278
            L GVKI+VI +F G A ASIALCTR++PGLEQKIVLPRDSYLQ YF+++++YLR+GPPLY
Sbjct: 856  LWGVKIVVISLFLGCALASIALCTRIEPGLEQKIVLPRDSYLQGYFNNVSEYLRIGPPLY 915

Query: 2279 FVVKDFNYSLESRNTNQICSISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWL 2458
            FVVK++NYS ESR+TNQ+CSISQC+S+SLLNEI +ASL P SSYIA PAASWLDDFL+W+
Sbjct: 916  FVVKNYNYSSESRHTNQLCSISQCESDSLLNEIARASLTPESSYIAMPAASWLDDFLVWM 975

Query: 2459 SPEAFSCCRKFLNGSYXXXXXXXXXXXXXXGLCNMGTTCKDCTTCYRYSDLHDGRPSTMD 2638
            SPEAF CCRKF NGSY                C +   CKDCTTC+R+SDL + RPST+ 
Sbjct: 976  SPEAFGCCRKFTNGSYCPPDDQPPCCSSNDVACGVNGVCKDCTTCFRHSDLQNDRPSTLQ 1035

Query: 2639 FKVKLPWFLNALPSSNCAKGGKGAYTSSVDLSGYESGIIQASSFRTYHTPLNRQIDYVNS 2818
            FK KLPWFL+ALPS++CAKGG GAYT+SV+L GY++GIIQASSFRTYHTPLN+Q+DYVNS
Sbjct: 1036 FKEKLPWFLDALPSADCAKGGHGAYTTSVELEGYDNGIIQASSFRTYHTPLNKQVDYVNS 1095

Query: 2819 MKAALDFXXXXXXXXXMEIFPYSVFYIFFEQYLDIWRTALINISIGLGAVFVVCLVLTGS 2998
            M+AA +F         +EIFPYSVFY+FFEQYLDIWRTALIN++I +GAVF+VCL++T S
Sbjct: 1096 MRAAREFSSKVSDSLKIEIFPYSVFYMFFEQYLDIWRTALINLAIAIGAVFIVCLIITSS 1155

Query: 2999 IWVSTIILAVLVMIVIDMLGLMAILGIQLNAISVVNLVMSIGIAVEFCVHITHAFLLSSG 3178
             W S IIL VL MIV+D++G+MAIL IQLNA+SVVNLVMS+GIAVEFCVH+THAF +SSG
Sbjct: 1156 FWSSAIILLVLAMIVVDLMGVMAILEIQLNAVSVVNLVMSVGIAVEFCVHMTHAFSVSSG 1215

Query: 3179 DRETRMKMALSTMGASVFSGITLTKLVGV 3265
            D++ R K AL TMGASVFSGITLTKLVGV
Sbjct: 1216 DKDQRTKEALGTMGASVFSGITLTKLVGV 1244


>gb|OVA00612.1| Sterol-sensing domain [Macleaya cordata]
          Length = 1295

 Score =  843 bits (2179), Expect = 0.0
 Identities = 422/687 (61%), Positives = 516/687 (75%), Gaps = 5/687 (0%)
 Frame = +1

Query: 1    QQAIPLLVSCPACLRNFLNLFCELSCSPDQSLFINVTSVKKVNDSMTVDMIDYFITPYFG 180
            QQAIP LV CPACLRNFLNLFCELSCSP+QS FINVTS+ KVN+++TVD ID+++T  FG
Sbjct: 112  QQAIPFLVGCPACLRNFLNLFCELSCSPNQSQFINVTSISKVNNNLTVDGIDFYVTDAFG 171

Query: 181  EQLFNSCKDVKFGTLNTRAMDFVGGGAQNYTEWFAFLGHRANLSMPGSPYAIAFQSIISD 360
            E+L+NSCKDVKFGT+NTRA++F+G GA+N+ EWFAF+GH+A L++PGSPYA+ F+S    
Sbjct: 172  EELYNSCKDVKFGTMNTRAIEFIGAGAKNFKEWFAFIGHQAGLNVPGSPYAMNFRSAAPP 231

Query: 361  LSGVRPLNATVYSCGDTSLGCSCGDCPSSALCVGSLQPAPHVKRSCSVKIASLKVKCLDF 540
             SG++P+N +VYSCGDTSLGCSCGDCPSS  C  S  P+PH KRSCS++I SLKVKCLDF
Sbjct: 232  SSGMKPMNVSVYSCGDTSLGCSCGDCPSSPTCSSSTPPSPHKKRSCSIRIGSLKVKCLDF 291

Query: 541  SLVIVYLFLLPAFLLWGSWYQKKKADP-SRTEPFFNANGG---NSSDKQENRSP-QISEA 705
            SL I+Y+ L+  F  WG ++++++  P SR +P  N       +S +KQ++  P Q+ E 
Sbjct: 292  SLAILYIVLVSTFFGWGLFHKRERRSPASRLKPLLNVRDEGELHSVNKQKDTHPVQMPEE 351

Query: 706  VPSVIKANRPSVVQLYLSSFFRKYGNFISRHPTXXXXXXXXXXXXXXXXXIRFKVETRPE 885
            +P V+K  + S VQ Y+SSF+R+YG +++R+PT                 IRFKVETRPE
Sbjct: 352  LPRVMKGIQLSAVQGYMSSFYRRYGAWVARNPTLVLCSSLAVVLLLCLGLIRFKVETRPE 411

Query: 886  KLWVGPGSKAAKEKLYFDSHLAPFYRIEQFILANISASNGENPPNIVTEENVKLLFQIQK 1065
            KLWVG GSKAA+EK +FD+HLAPFYRIEQ ILA +  S     P+IVTE+N +LLF++QK
Sbjct: 412  KLWVGHGSKAAEEKQFFDTHLAPFYRIEQLILATVPDSKLGKAPSIVTEDNFQLLFEVQK 471

Query: 1066 KVDDLHANYSGSVVSLPDICLKPLGNDCATQSILQYFQMDPQNYDAYGGLAHLQYCFEHF 1245
            KVD + ANYSGS+VSL DIC+KPLG DCATQS+LQYF+MDP NYD YGG+ H +YCF+H+
Sbjct: 472  KVDGIRANYSGSMVSLTDICMKPLGEDCATQSVLQYFKMDPDNYDDYGGVQHAEYCFQHY 531

Query: 1246 SSEKSCLSAFSAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDKTSSEYRNAVAWEKA 1425
            +S  +CLSAF  PLDPSTALGGFSGNNYSEASAFVITYPV N +D+T +    AVAWEKA
Sbjct: 532  TSAVTCLSAFQGPLDPSTALGGFSGNNYSEASAFVITYPVENKIDQTGNGNGKAVAWEKA 591

Query: 1426 FVQLMKDEIIPMVXXXXXXXXXXXXXXXXXXXKRESTADAITIFISYLVMFAYISVTLGN 1605
            F+ L+K+E++P+V                   KRESTADAITI ISY+VMFAYIS+TLG+
Sbjct: 592  FIHLVKEELLPLVQAKNLTLSFSSESSIQEELKRESTADAITILISYIVMFAYISMTLGD 651

Query: 1606 RHHLSSIFXXXXXXXXXXXXXXXXXXXXXXXXFYSAIGVKSTLIIMEVIPFLVLAVGVDN 1785
               LSS +                        F+SAIGVKSTLII+EVIPFLVLAVGVDN
Sbjct: 652  TPRLSSFYISSKVLLGLSGVVVVMLSVLGSVGFFSAIGVKSTLIIIEVIPFLVLAVGVDN 711

Query: 1786 MCILVHTIKRQPLELLLEERISSALADVGPSITLASLSEVLAFAVGSFIPMPACRVFSMX 1965
            MCILVH +KRQPLEL LEERIS+AL +VGPSITLASLSEVLAFAVGSFI MPACRVFSM 
Sbjct: 712  MCILVHAVKRQPLELPLEERISNALVEVGPSITLASLSEVLAFAVGSFISMPACRVFSMF 771

Query: 1966 XXXXXXXXXXXQVTAFVSLIIFDFLRA 2046
                       QVTAFV+LI+FDFLRA
Sbjct: 772  AALAVFLDFLLQVTAFVALIVFDFLRA 798



 Score =  582 bits (1501), Expect = 0.0
 Identities = 279/389 (71%), Positives = 328/389 (84%)
 Frame = +2

Query: 2099 LRGVKIIVILVFSGFAFASIALCTRVQPGLEQKIVLPRDSYLQNYFDDLAKYLRVGPPLY 2278
            L GVKI+V+ VF GFA ASIALCTR++PGLEQK+VLPRDSYLQ YF+++ +YLRVGPPLY
Sbjct: 842  LWGVKIVVVAVFVGFALASIALCTRIEPGLEQKVVLPRDSYLQGYFNNVTEYLRVGPPLY 901

Query: 2279 FVVKDFNYSLESRNTNQICSISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWL 2458
            FVVKD+NYS ESR+TNQ+CSISQCDSNSLLNEI +AS +P SSYIAKPAASWLDDFL+W+
Sbjct: 902  FVVKDYNYSSESRHTNQLCSISQCDSNSLLNEIARASSIPESSYIAKPAASWLDDFLVWM 961

Query: 2459 SPEAFSCCRKFLNGSYXXXXXXXXXXXXXXGLCNMGTTCKDCTTCYRYSDLHDGRPSTMD 2638
            SPEAF CCRKF NGSY              G C +G  CKDCTTC+R+SDL++ RP+T  
Sbjct: 962  SPEAFGCCRKFTNGSYCPPDDQPPCCSPDEGSCGLGGVCKDCTTCFRHSDLNNDRPTTAQ 1021

Query: 2639 FKVKLPWFLNALPSSNCAKGGKGAYTSSVDLSGYESGIIQASSFRTYHTPLNRQIDYVNS 2818
            F+ KLPWFLN+LPS++CAKGG GAYT+SVDL+GYESG+IQAS FRTYHTPLN+Q D+VNS
Sbjct: 1022 FREKLPWFLNSLPSADCAKGGHGAYTNSVDLNGYESGLIQASEFRTYHTPLNKQSDFVNS 1081

Query: 2819 MKAALDFXXXXXXXXXMEIFPYSVFYIFFEQYLDIWRTALINISIGLGAVFVVCLVLTGS 2998
            ++AA +F         +EIFPY++FYIFFEQYLDIWRTALINI+I L AVF+VCL++T S
Sbjct: 1082 LRAAREFSSRVSDSLNIEIFPYAMFYIFFEQYLDIWRTALINIAIALAAVFIVCLIITCS 1141

Query: 2999 IWVSTIILAVLVMIVIDMLGLMAILGIQLNAISVVNLVMSIGIAVEFCVHITHAFLLSSG 3178
            +W S IIL VL MIVID++G+MA+L IQLNA+SVVNLVM+IGIAVEFCVHITHAF +SSG
Sbjct: 1142 LWSSAIILLVLTMIVIDLMGVMALLNIQLNAVSVVNLVMAIGIAVEFCVHITHAFSVSSG 1201

Query: 3179 DRETRMKMALSTMGASVFSGITLTKLVGV 3265
            DR  R K AL TMGASVFSGITLTKLVGV
Sbjct: 1202 DRGQRAKEALGTMGASVFSGITLTKLVGV 1230


>emb|CBI40718.3| unnamed protein product, partial [Vitis vinifera]
          Length = 1242

 Score =  840 bits (2170), Expect = 0.0
 Identities = 419/688 (60%), Positives = 517/688 (75%), Gaps = 6/688 (0%)
 Frame = +1

Query: 1    QQAIPLLVSCPACLRNFLNLFCELSCSPDQSLFINVTSVKKVNDSMTVDMIDYFITPYFG 180
            QQAIP LV CPACLRNFLNLFCEL+CSP+QSLFINVTSV KVN+++TVD I++ IT  FG
Sbjct: 59   QQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVSKVNNNLTVDGIEFIITDAFG 118

Query: 181  EQLFNSCKDVKFGTLNTRAMDFVGGGAQNYTEWFAFLGHRANLSMPGSPYAIAFQSIISD 360
            E L+NSCKDVKFGT+NTRA+DF+G GA+ + EWFAF+G RA  S+PGSPYAI FQ  I++
Sbjct: 119  EGLYNSCKDVKFGTMNTRAIDFIGAGAKTFKEWFAFIGTRAAPSVPGSPYAINFQPSIAE 178

Query: 361  LSGVRPLNATVYSCGDTSLGCSCGDCPSSALCVGSLQPAPHVKRSCSVKIASLKVKCLDF 540
             SG++P+N + YSCGD SLGCSCGDCPS+++C G   P+ H + SCSV+I SLK KC++F
Sbjct: 179  SSGMKPMNVSTYSCGDNSLGCSCGDCPSASVCSGYAPPSLHKEGSCSVRIGSLKAKCIEF 238

Query: 541  SLVIVYLFLLPAFLLWGSWYQKKKADPS-RTEPFFNANGGN-----SSDKQENRSPQISE 702
            SL I+Y+ L+  F  WG +++ ++ +P+ R +P  N   G+     +  K EN S Q+ E
Sbjct: 239  SLAILYIILVTIFFGWGLFHRTRERNPAPRMKPMLNVMDGSELHSMNRPKDENLSSQMLE 298

Query: 703  AVPSVIKANRPSVVQLYLSSFFRKYGNFISRHPTXXXXXXXXXXXXXXXXXIRFKVETRP 882
             VP +    + S+VQ Y+S+F+R+YG +++RHPT                 IRFKVETRP
Sbjct: 299  DVPQIRNGVQLSIVQGYMSNFYRRYGTWVARHPTIMLCSSLAIVLVLCLGLIRFKVETRP 358

Query: 883  EKLWVGPGSKAAKEKLYFDSHLAPFYRIEQFILANISASNGENPPNIVTEENVKLLFQIQ 1062
            EKLWVGPGSKAA+EK +FDSHLAPFYRIEQ +LA I  +NG + P+IVTE N+KLLF+IQ
Sbjct: 359  EKLWVGPGSKAAEEKQFFDSHLAPFYRIEQLVLATIPDANGIS-PSIVTENNIKLLFEIQ 417

Query: 1063 KKVDDLHANYSGSVVSLPDICLKPLGNDCATQSILQYFQMDPQNYDAYGGLAHLQYCFEH 1242
            KKVD L AN+SGS++SL DIC+KPLG DCATQS+LQYF+MD +NYD YGG+ H++YCF+H
Sbjct: 418  KKVDGLRANFSGSMISLTDICMKPLGQDCATQSVLQYFKMDSRNYDDYGGVQHVEYCFQH 477

Query: 1243 FSSEKSCLSAFSAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDKTSSEYRNAVAWEK 1422
            ++S  +C+SAF APLDPSTALGGFSGNNYSEASAF++TYPVNN +DK  +E   AVAWEK
Sbjct: 478  YTSADTCMSAFKAPLDPSTALGGFSGNNYSEASAFIVTYPVNNAIDKEGNETGKAVAWEK 537

Query: 1423 AFVQLMKDEIIPMVXXXXXXXXXXXXXXXXXXXKRESTADAITIFISYLVMFAYISVTLG 1602
            AF+Q++KD+++PM+                   KRESTADAITI ISYLVMFAYIS+TLG
Sbjct: 538  AFIQIVKDDLLPMMQSKNLTLSFSSESSIEEELKRESTADAITISISYLVMFAYISLTLG 597

Query: 1603 NRHHLSSIFXXXXXXXXXXXXXXXXXXXXXXXXFYSAIGVKSTLIIMEVIPFLVLAVGVD 1782
            +   LSS +                        F+SAIGVKSTLIIMEVIPFLVLAVGVD
Sbjct: 598  DTPRLSSFYISSKIFLGLAGVMLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVGVD 657

Query: 1783 NMCILVHTIKRQPLELLLEERISSALADVGPSITLASLSEVLAFAVGSFIPMPACRVFSM 1962
            NMCILVH +KRQPLEL LE RIS+AL +VGPSITLASL+EVLAFAVG+FIPMPACRVFSM
Sbjct: 658  NMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLAEVLAFAVGTFIPMPACRVFSM 717

Query: 1963 XXXXXXXXXXXXQVTAFVSLIIFDFLRA 2046
                        QVTAFV+LI+FDFLRA
Sbjct: 718  FAALAVLLDFLLQVTAFVALIVFDFLRA 745



 Score =  580 bits (1495), Expect = 0.0
 Identities = 279/389 (71%), Positives = 330/389 (84%)
 Frame = +2

Query: 2099 LRGVKIIVILVFSGFAFASIALCTRVQPGLEQKIVLPRDSYLQNYFDDLAKYLRVGPPLY 2278
            L GVK++VI VF  FA ASIALCTR++PGLEQKIVLPRDSYLQ YF+++++YLR+GPPLY
Sbjct: 791  LWGVKLVVISVFVAFALASIALCTRIEPGLEQKIVLPRDSYLQGYFNNVSEYLRIGPPLY 850

Query: 2279 FVVKDFNYSLESRNTNQICSISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWL 2458
            FVVK++NYS ESR+TNQ+CSISQC+S+SLLNEI +ASL+P SSYIAKPAASWLDDFL+W+
Sbjct: 851  FVVKNYNYSSESRHTNQLCSISQCNSDSLLNEIARASLIPESSYIAKPAASWLDDFLVWI 910

Query: 2459 SPEAFSCCRKFLNGSYXXXXXXXXXXXXXXGLCNMGTTCKDCTTCYRYSDLHDGRPSTMD 2638
            SPEAF CCRKF NGSY              G C +   CKDCTTC+R+SDL++ RPST  
Sbjct: 911  SPEAFGCCRKFTNGSYCPPNDQPPCCASEDGSCYLNGLCKDCTTCFRHSDLYNDRPSTAQ 970

Query: 2639 FKVKLPWFLNALPSSNCAKGGKGAYTSSVDLSGYESGIIQASSFRTYHTPLNRQIDYVNS 2818
            F+ KLPWFL ALPS++C+KGG GAYTSSV+L G+ESGIIQASSFRTYHTPLN+QIDYVNS
Sbjct: 971  FREKLPWFLAALPSADCSKGGHGAYTSSVELKGFESGIIQASSFRTYHTPLNKQIDYVNS 1030

Query: 2819 MKAALDFXXXXXXXXXMEIFPYSVFYIFFEQYLDIWRTALINISIGLGAVFVVCLVLTGS 2998
            M+AA +F         ++IFPYSVFY+FFEQYLDIWRTALIN++I +GAVF+VCLV+T S
Sbjct: 1031 MRAAREFTSRVSDSLKIQIFPYSVFYMFFEQYLDIWRTALINLAIAIGAVFIVCLVITCS 1090

Query: 2999 IWVSTIILAVLVMIVIDMLGLMAILGIQLNAISVVNLVMSIGIAVEFCVHITHAFLLSSG 3178
            +W S IIL VL MIV+D++G+MAIL IQLNA+SVVNLVM++GIAVEFCVHITHAF +SSG
Sbjct: 1091 LWSSAIILLVLAMIVVDLMGVMAILNIQLNALSVVNLVMAVGIAVEFCVHITHAFSVSSG 1150

Query: 3179 DRETRMKMALSTMGASVFSGITLTKLVGV 3265
            DR  RMK AL TMGASVFSGITLTKLVGV
Sbjct: 1151 DRNQRMKEALGTMGASVFSGITLTKLVGV 1179


>ref|XP_018836419.1| PREDICTED: Niemann-Pick C1 protein-like isoform X2 [Juglans regia]
          Length = 1175

 Score =  837 bits (2161), Expect = 0.0
 Identities = 420/688 (61%), Positives = 507/688 (73%), Gaps = 6/688 (0%)
 Frame = +1

Query: 1    QQAIPLLVSCPACLRNFLNLFCELSCSPDQSLFINVTSVKKVNDSMTVDMIDYFITPYFG 180
            QQAIP LV CPACLRNFLNLFCEL+CSP+QSLFINVTSV KVN ++TVD ID++IT  FG
Sbjct: 118  QQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVSKVNSNLTVDGIDFYITDAFG 177

Query: 181  EQLFNSCKDVKFGTLNTRAMDFVGGGAQNYTEWFAFLGHRANLSMPGSPYAIAFQSIISD 360
            E L++SCKDVK+GT+N+RA++F+G GAQN+ EWFAF+G RA L++PGSPYAI F S  ++
Sbjct: 178  EGLYDSCKDVKYGTMNSRALEFIGAGAQNFKEWFAFIGRRAGLNLPGSPYAIVFHSNAAE 237

Query: 361  LSGVRPLNATVYSCGDTSLGCSCGDCPSSALCVGSLQPAPHVKRSCSVKIASLKVKCLDF 540
             SG++P+N T YSCGD SL CSCGDC SS +C  +  PA H + SCSV+I SLK KC+DF
Sbjct: 238  SSGMKPMNVTSYSCGDISLRCSCGDCRSSPVCTNTSPPATHKRGSCSVRIGSLKAKCIDF 297

Query: 541  SLVIVYLFLLPAFLLWGSWYQKKKADP-SRTEPFFNANGGN-----SSDKQENRSPQISE 702
            +L I+Y+ L+  FL WG ++  ++ +P SRT+P  NA         +  K EN   Q+ E
Sbjct: 298  ALAILYVVLVSIFLGWGLFHHTRERNPHSRTKPVLNAMDVGQLHSVNRKKDENFPMQMLE 357

Query: 703  AVPSVIKANRPSVVQLYLSSFFRKYGNFISRHPTXXXXXXXXXXXXXXXXXIRFKVETRP 882
              P +    R SVVQ Y+S+F+R+YG +++R+PT                 IRFKVETRP
Sbjct: 358  DSPQIGNGVRLSVVQGYMSNFYRRYGTWVARNPTLVLCSSLAIVLMLCLGLIRFKVETRP 417

Query: 883  EKLWVGPGSKAAKEKLYFDSHLAPFYRIEQFILANISASNGENPPNIVTEENVKLLFQIQ 1062
            EKLWVGPGS+AA+EK +FDSHLAPFYRIEQ ILA I  +     P+IVTE N+KLLF+IQ
Sbjct: 418  EKLWVGPGSRAAEEKQFFDSHLAPFYRIEQIILATIPDAMDGRSPSIVTESNIKLLFEIQ 477

Query: 1063 KKVDDLHANYSGSVVSLPDICLKPLGNDCATQSILQYFQMDPQNYDAYGGLAHLQYCFEH 1242
            KKVD +HANYSGS++SL DIC+KPL  DCATQS+LQYF+MDP+NYD YGG+ HL+YCF+H
Sbjct: 478  KKVDGIHANYSGSMISLSDICMKPLDQDCATQSVLQYFKMDPENYDNYGGVEHLEYCFQH 537

Query: 1243 FSSEKSCLSAFSAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDKTSSEYRNAVAWEK 1422
            +SS   C+SAF APLDPSTALGGF  NNYSEASAF++TYPVNN +DK  +E + AVAWEK
Sbjct: 538  YSSADKCMSAFKAPLDPSTALGGFPANNYSEASAFIVTYPVNNAIDKEGNETQRAVAWEK 597

Query: 1423 AFVQLMKDEIIPMVXXXXXXXXXXXXXXXXXXXKRESTADAITIFISYLVMFAYISVTLG 1602
            AF+QL+KDE++P+                    KRESTADAITI ISYLVMFAYIS+TLG
Sbjct: 598  AFIQLVKDELLPLAQSQNLTLSFSSESSIEEELKRESTADAITILISYLVMFAYISLTLG 657

Query: 1603 NRHHLSSIFXXXXXXXXXXXXXXXXXXXXXXXXFYSAIGVKSTLIIMEVIPFLVLAVGVD 1782
            +   LSS +                        F+S IGVKSTLIIMEVIPFLVLAVGVD
Sbjct: 658  DTPRLSSFYISSKMLLGFSGVILVVLSVLASVGFFSVIGVKSTLIIMEVIPFLVLAVGVD 717

Query: 1783 NMCILVHTIKRQPLELLLEERISSALADVGPSITLASLSEVLAFAVGSFIPMPACRVFSM 1962
            NMCILVH +KRQPLEL LE RIS+AL +VGPSITLASLSEVLAFAVGSFIPMPACRVFSM
Sbjct: 718  NMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSM 777

Query: 1963 XXXXXXXXXXXXQVTAFVSLIIFDFLRA 2046
                        QVTAFV+LI+FDFLRA
Sbjct: 778  FAALAVLLDFLLQVTAFVALIVFDFLRA 805



 Score =  462 bits (1190), Expect = e-140
 Identities = 219/319 (68%), Positives = 259/319 (81%)
 Frame = +2

Query: 2099 LRGVKIIVILVFSGFAFASIALCTRVQPGLEQKIVLPRDSYLQNYFDDLAKYLRVGPPLY 2278
            L GVKI+VI VF G+A ASIALCTR++PGLEQKIVLPRDSYLQ Y +D+++YLR+GPPLY
Sbjct: 851  LWGVKIVVISVFLGYALASIALCTRIEPGLEQKIVLPRDSYLQGYLNDVSEYLRIGPPLY 910

Query: 2279 FVVKDFNYSLESRNTNQICSISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWL 2458
            FVVK++NYS ESR+TNQ+CSISQCDS+SLLNEI + SL P SSYIAKPAASWLDDFL+W+
Sbjct: 911  FVVKNYNYSSESRHTNQLCSISQCDSDSLLNEIARESLTPDSSYIAKPAASWLDDFLLWM 970

Query: 2459 SPEAFSCCRKFLNGSYXXXXXXXXXXXXXXGLCNMGTTCKDCTTCYRYSDLHDGRPSTMD 2638
            SPEAF CCRKF N SY                C +   CKDCTTC+R+SDLH+ RPST+ 
Sbjct: 971  SPEAFGCCRKFTNQSYCPPDDQPPCCSPNEVSCGLDGVCKDCTTCFRHSDLHNDRPSTVQ 1030

Query: 2639 FKVKLPWFLNALPSSNCAKGGKGAYTSSVDLSGYESGIIQASSFRTYHTPLNRQIDYVNS 2818
            FK KLPWFLN+LPS+ CAKGG GAYTSSV+L GYE+ +I ASSFRTYHTPLNRQIDYVNS
Sbjct: 1031 FKEKLPWFLNSLPSAACAKGGHGAYTSSVELKGYENSVIPASSFRTYHTPLNRQIDYVNS 1090

Query: 2819 MKAALDFXXXXXXXXXMEIFPYSVFYIFFEQYLDIWRTALINISIGLGAVFVVCLVLTGS 2998
            M+AA +F         +EIFPYSVFY+FFEQYLDIWRTALIN++I +GAVF+VCLV+T S
Sbjct: 1091 MRAAREFTSKISDSLKIEIFPYSVFYMFFEQYLDIWRTALINLAIAIGAVFIVCLVITCS 1150

Query: 2999 IWVSTIILAVLVMIVIDML 3055
             W S II  VL MI++D++
Sbjct: 1151 FWSSAIIFLVLAMILVDLM 1169


>ref|XP_019072216.1| PREDICTED: Niemann-Pick C1 protein [Vitis vinifera]
          Length = 1292

 Score =  840 bits (2170), Expect = 0.0
 Identities = 419/688 (60%), Positives = 517/688 (75%), Gaps = 6/688 (0%)
 Frame = +1

Query: 1    QQAIPLLVSCPACLRNFLNLFCELSCSPDQSLFINVTSVKKVNDSMTVDMIDYFITPYFG 180
            QQAIP LV CPACLRNFLNLFCEL+CSP+QSLFINVTSV KVN+++TVD I++ IT  FG
Sbjct: 109  QQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVSKVNNNLTVDGIEFIITDAFG 168

Query: 181  EQLFNSCKDVKFGTLNTRAMDFVGGGAQNYTEWFAFLGHRANLSMPGSPYAIAFQSIISD 360
            E L+NSCKDVKFGT+NTRA+DF+G GA+ + EWFAF+G RA  S+PGSPYAI FQ  I++
Sbjct: 169  EGLYNSCKDVKFGTMNTRAIDFIGAGAKTFKEWFAFIGTRAAPSVPGSPYAINFQPSIAE 228

Query: 361  LSGVRPLNATVYSCGDTSLGCSCGDCPSSALCVGSLQPAPHVKRSCSVKIASLKVKCLDF 540
             SG++P+N + YSCGD SLGCSCGDCPS+++C G   P+ H + SCSV+I SLK KC++F
Sbjct: 229  SSGMKPMNVSTYSCGDNSLGCSCGDCPSASVCSGYAPPSLHKEGSCSVRIGSLKAKCIEF 288

Query: 541  SLVIVYLFLLPAFLLWGSWYQKKKADPS-RTEPFFNANGGN-----SSDKQENRSPQISE 702
            SL I+Y+ L+  F  WG +++ ++ +P+ R +P  N   G+     +  K EN S Q+ E
Sbjct: 289  SLAILYIILVTIFFGWGLFHRTRERNPAPRMKPMLNVMDGSELHSMNRPKDENLSSQMLE 348

Query: 703  AVPSVIKANRPSVVQLYLSSFFRKYGNFISRHPTXXXXXXXXXXXXXXXXXIRFKVETRP 882
             VP +    + S+VQ Y+S+F+R+YG +++RHPT                 IRFKVETRP
Sbjct: 349  DVPQIRNGVQLSIVQGYMSNFYRRYGTWVARHPTIMLCSSLAIVLVLCLGLIRFKVETRP 408

Query: 883  EKLWVGPGSKAAKEKLYFDSHLAPFYRIEQFILANISASNGENPPNIVTEENVKLLFQIQ 1062
            EKLWVGPGSKAA+EK +FDSHLAPFYRIEQ +LA I  +NG + P+IVTE N+KLLF+IQ
Sbjct: 409  EKLWVGPGSKAAEEKQFFDSHLAPFYRIEQLVLATIPDANGIS-PSIVTENNIKLLFEIQ 467

Query: 1063 KKVDDLHANYSGSVVSLPDICLKPLGNDCATQSILQYFQMDPQNYDAYGGLAHLQYCFEH 1242
            KKVD L AN+SGS++SL DIC+KPLG DCATQS+LQYF+MD +NYD YGG+ H++YCF+H
Sbjct: 468  KKVDGLRANFSGSMISLTDICMKPLGQDCATQSVLQYFKMDSRNYDDYGGVQHVEYCFQH 527

Query: 1243 FSSEKSCLSAFSAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDKTSSEYRNAVAWEK 1422
            ++S  +C+SAF APLDPSTALGGFSGNNYSEASAF++TYPVNN +DK  +E   AVAWEK
Sbjct: 528  YTSADTCMSAFKAPLDPSTALGGFSGNNYSEASAFIVTYPVNNAIDKEGNETGKAVAWEK 587

Query: 1423 AFVQLMKDEIIPMVXXXXXXXXXXXXXXXXXXXKRESTADAITIFISYLVMFAYISVTLG 1602
            AF+Q++KD+++PM+                   KRESTADAITI ISYLVMFAYIS+TLG
Sbjct: 588  AFIQIVKDDLLPMMQSKNLTLSFSSESSIEEELKRESTADAITISISYLVMFAYISLTLG 647

Query: 1603 NRHHLSSIFXXXXXXXXXXXXXXXXXXXXXXXXFYSAIGVKSTLIIMEVIPFLVLAVGVD 1782
            +   LSS +                        F+SAIGVKSTLIIMEVIPFLVLAVGVD
Sbjct: 648  DTPRLSSFYISSKIFLGLAGVMLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVGVD 707

Query: 1783 NMCILVHTIKRQPLELLLEERISSALADVGPSITLASLSEVLAFAVGSFIPMPACRVFSM 1962
            NMCILVH +KRQPLEL LE RIS+AL +VGPSITLASL+EVLAFAVG+FIPMPACRVFSM
Sbjct: 708  NMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLAEVLAFAVGTFIPMPACRVFSM 767

Query: 1963 XXXXXXXXXXXXQVTAFVSLIIFDFLRA 2046
                        QVTAFV+LI+FDFLRA
Sbjct: 768  FAALAVLLDFLLQVTAFVALIVFDFLRA 795



 Score =  580 bits (1495), Expect = 0.0
 Identities = 279/389 (71%), Positives = 330/389 (84%)
 Frame = +2

Query: 2099 LRGVKIIVILVFSGFAFASIALCTRVQPGLEQKIVLPRDSYLQNYFDDLAKYLRVGPPLY 2278
            L GVK++VI VF  FA ASIALCTR++PGLEQKIVLPRDSYLQ YF+++++YLR+GPPLY
Sbjct: 841  LWGVKLVVISVFVAFALASIALCTRIEPGLEQKIVLPRDSYLQGYFNNVSEYLRIGPPLY 900

Query: 2279 FVVKDFNYSLESRNTNQICSISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWL 2458
            FVVK++NYS ESR+TNQ+CSISQC+S+SLLNEI +ASL+P SSYIAKPAASWLDDFL+W+
Sbjct: 901  FVVKNYNYSSESRHTNQLCSISQCNSDSLLNEIARASLIPESSYIAKPAASWLDDFLVWI 960

Query: 2459 SPEAFSCCRKFLNGSYXXXXXXXXXXXXXXGLCNMGTTCKDCTTCYRYSDLHDGRPSTMD 2638
            SPEAF CCRKF NGSY              G C +   CKDCTTC+R+SDL++ RPST  
Sbjct: 961  SPEAFGCCRKFTNGSYCPPNDQPPCCASEDGSCYLNGLCKDCTTCFRHSDLYNDRPSTAQ 1020

Query: 2639 FKVKLPWFLNALPSSNCAKGGKGAYTSSVDLSGYESGIIQASSFRTYHTPLNRQIDYVNS 2818
            F+ KLPWFL ALPS++C+KGG GAYTSSV+L G+ESGIIQASSFRTYHTPLN+QIDYVNS
Sbjct: 1021 FREKLPWFLAALPSADCSKGGHGAYTSSVELKGFESGIIQASSFRTYHTPLNKQIDYVNS 1080

Query: 2819 MKAALDFXXXXXXXXXMEIFPYSVFYIFFEQYLDIWRTALINISIGLGAVFVVCLVLTGS 2998
            M+AA +F         ++IFPYSVFY+FFEQYLDIWRTALIN++I +GAVF+VCLV+T S
Sbjct: 1081 MRAAREFTSRVSDSLKIQIFPYSVFYMFFEQYLDIWRTALINLAIAIGAVFIVCLVITCS 1140

Query: 2999 IWVSTIILAVLVMIVIDMLGLMAILGIQLNAISVVNLVMSIGIAVEFCVHITHAFLLSSG 3178
            +W S IIL VL MIV+D++G+MAIL IQLNA+SVVNLVM++GIAVEFCVHITHAF +SSG
Sbjct: 1141 LWSSAIILLVLAMIVVDLMGVMAILNIQLNALSVVNLVMAVGIAVEFCVHITHAFSVSSG 1200

Query: 3179 DRETRMKMALSTMGASVFSGITLTKLVGV 3265
            DR  RMK AL TMGASVFSGITLTKLVGV
Sbjct: 1201 DRNQRMKEALGTMGASVFSGITLTKLVGV 1229


>gb|OAY77489.1| Niemann-Pick C1 protein [Ananas comosus]
          Length = 1203

 Score =  835 bits (2157), Expect = 0.0
 Identities = 435/690 (63%), Positives = 507/690 (73%), Gaps = 8/690 (1%)
 Frame = +1

Query: 1    QQAIPLLVSCPACLRNFLNLFCELSCSPDQSLFINVTSVKKVNDSMTVDMIDYFITPYFG 180
            QQAIP LV CPACLRNFLN+FCELSCSP+QSLFINVTS+ +VN++MTVD ID+F+T  +G
Sbjct: 131  QQAIPFLVGCPACLRNFLNIFCELSCSPNQSLFINVTSIAEVNNTMTVDGIDFFVTSEYG 190

Query: 181  EQLFNSCKDVKFGTLNTRAMDFVGGGAQNYTEWFAFLGHRANLSMPGSPYAIAFQSIISD 360
            E+L+NSCKDVKFGT+NTR+MDF+GG AQNYTEWFAFLG +ANL+ PGSPYA++F+S ISD
Sbjct: 191  EELYNSCKDVKFGTMNTRSMDFIGGAAQNYTEWFAFLGRQANLNEPGSPYAVSFRSDISD 250

Query: 361  LSGVRPLNATVYSCGDTSLGCSCGDCPSSALCVGSLQPAPHVKRSCSVKIASLKVKCLDF 540
             SG++PLN TVYSCGD SLGCSCGDCPSS++C+ +   A   KRSCS K+ SLKVKCL+F
Sbjct: 251  SSGMKPLNITVYSCGDHSLGCSCGDCPSSSVCMNNAPSASRGKRSCSFKMGSLKVKCLEF 310

Query: 541  SLVIVYLFLLPAFLLWGSWYQKKKADP--SRTEPFFNANGGN-----SSDKQENRSPQIS 699
            SL IVY  LL AFL W S ++K++     SRTEP  N    N     S ++   R  QI+
Sbjct: 311  SLAIVYFVLLAAFLTWVSLHRKRERVGLFSRTEPLQNVQDQNQLHSVSKEELSGRPLQIT 370

Query: 700  EAVPSVIKANRPSVVQLYLSSFFRKYGNFISRHPTXXXXXXXXXXXXXXXXXIRFKVETR 879
            E VP V +  RPSVVQ Y++SFFRKYG F++R+P                  IRFKVETR
Sbjct: 371  EEVPLVAETLRPSVVQSYMTSFFRKYGTFVARNPILVLCLSLAVPLLICIGLIRFKVETR 430

Query: 880  PEKLWVGPGSKAAKEKLYFDSHLAPFYRIEQFILANISASNGENPPNIVTEENVKLLFQI 1059
             EKLWVGPGSKAA+EK YFDSHLAPFYRIEQ I+A I AS   + P IVT  N++LLF++
Sbjct: 431  AEKLWVGPGSKAAEEKQYFDSHLAPFYRIEQLIVATIPASRTSSSPTIVTGNNIQLLFEV 490

Query: 1060 QKKVDDLHANYSGSVVSLPDICLKPLGNDCATQSILQYFQMDPQNYDAYGGLAHLQYCFE 1239
            QKKVD L ANYSG++VSL DIC KPLG DCATQS+LQYFQMDPQ Y+   G+ H +YCF+
Sbjct: 491  QKKVDGLRANYSGNMVSLSDICFKPLGADCATQSVLQYFQMDPQKYNDL-GIDHAKYCFQ 549

Query: 1240 HFSSEKSCLSAFSAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDKTSSEYRNAVAWE 1419
            H SS++SCLSAF APLDPSTALGGFSGNNYSEASAFVITYPVNN +DKT  E   AVAWE
Sbjct: 550  HSSSDESCLSAFQAPLDPSTALGGFSGNNYSEASAFVITYPVNNKVDKTGEENGKAVAWE 609

Query: 1420 KAFVQLMKDEIIPMVXXXXXXXXXXXXXXXXXXXKRESTADAITIFISYLVMFAYISVTL 1599
            +AF+ LMK+EI+PM+                   KRESTADAITI ISYLVMFAYIS  L
Sbjct: 610  EAFIHLMKEEIMPMIQMQNLTLAFSSESSIQEELKRESTADAITILISYLVMFAYISFAL 669

Query: 1600 GNRHHLSSIF-XXXXXXXXXXXXXXXXXXXXXXXXFYSAIGVKSTLIIMEVIPFLVLAVG 1776
            G+    SS F                         F++AIGVKSTLIIMEVIPFL   VG
Sbjct: 670  GDSFRCSSSFIISSKVLLGLSGVVLVLLSVLGSIGFFTAIGVKSTLIIMEVIPFL---VG 726

Query: 1777 VDNMCILVHTIKRQPLELLLEERISSALADVGPSITLASLSEVLAFAVGSFIPMPACRVF 1956
            VDNMCILVH +KRQPL L LE RIS+AL +VGPSITLASLSE LAFAV +F PMPACRVF
Sbjct: 727  VDNMCILVHAVKRQPLALSLEGRISNALVEVGPSITLASLSEFLAFAVSTFTPMPACRVF 786

Query: 1957 SMXXXXXXXXXXXXQVTAFVSLIIFDFLRA 2046
            SM            QVTAFV+LI+FDF+RA
Sbjct: 787  SMFAALAVLLDFLLQVTAFVALIVFDFIRA 816



 Score =  437 bits (1123), Expect = e-130
 Identities = 240/389 (61%), Positives = 264/389 (67%)
 Frame = +2

Query: 2099 LRGVKIIVILVFSGFAFASIALCTRVQPGLEQKIVLPRDSYLQNYFDDLAKYLRVGPPLY 2278
            LRGVK+IVI VF GFAF SIAL TR+QPGLEQKIVLPR+SYLQ+YFDDLAKYLR+GPPLY
Sbjct: 861  LRGVKVIVIAVFVGFAFTSIALSTRLQPGLEQKIVLPRNSYLQDYFDDLAKYLRIGPPLY 920

Query: 2279 FVVKDFNYSLESRNTNQICSISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWL 2458
            FVVKDFNYSLES  TNQICSISQC+SNSLLNEI KASLVP SSYIAKPAASWLDDFLIWL
Sbjct: 921  FVVKDFNYSLESSQTNQICSISQCNSNSLLNEIAKASLVPESSYIAKPAASWLDDFLIWL 980

Query: 2459 SPEAFSCCRKFLNGSYXXXXXXXXXXXXXXGLCNMGTTCKDCTTCYRYSDLHDGRPSTMD 2638
            SPEAFSCCR+F+NGSY                      C     C+R+SDLHDGRPST  
Sbjct: 981  SPEAFSCCREFVNGSY----------------------CPPDDQCFRHSDLHDGRPSTAQ 1018

Query: 2639 FKVKLPWFLNALPSSNCAKGGKGAYTSSVDLSGYESGIIQASSFRTYHTPLNRQIDYVNS 2818
            FK KLPWFLNALPSS+CAKGGKGAYT++V+L+GYE GIIQAS+FRTYHTPLN+Q DYVNS
Sbjct: 1019 FKEKLPWFLNALPSSDCAKGGKGAYTTNVNLTGYEHGIIQASAFRTYHTPLNKQTDYVNS 1078

Query: 2819 MKAALDFXXXXXXXXXMEIFPYSVFYIFFEQYLDIWRTALINISIGLGAVFVVCLVLTGS 2998
            MKAA DF                       +  D  +  +  + I L A+ VV LV+   
Sbjct: 1079 MKAARDFS---------------------SKISDSLQGVMGILDIQLNAISVVNLVM--- 1114

Query: 2999 IWVSTIILAVLVMIVIDMLGLMAILGIQLNAISVVNLVMSIGIAVEFCVHITHAFLLSSG 3178
                                                   SIGIAVEFCVHITHAF +S G
Sbjct: 1115 ---------------------------------------SIGIAVEFCVHITHAFSISRG 1135

Query: 3179 DRETRMKMALSTMGASVFSGITLTKLVGV 3265
            DR TR K AL TMGASVFSGITLTKLVGV
Sbjct: 1136 DRNTRAKEALCTMGASVFSGITLTKLVGV 1164


>gb|KDO85105.1| hypothetical protein CISIN_1g000762mg [Citrus sinensis]
          Length = 951

 Score =  826 bits (2133), Expect = 0.0
 Identities = 417/689 (60%), Positives = 506/689 (73%), Gaps = 7/689 (1%)
 Frame = +1

Query: 1    QQAIPLLVSCPACLRNFLNLFCELSCSPDQSLFINVTSVKKVNDSMTVDMIDYFITPYFG 180
            QQAIP LV CPACLRNFLNLFCEL+CSP+QSLFINVTSV KV++++TVD IDY+IT  FG
Sbjct: 113  QQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVSKVSNNLTVDGIDYYITDTFG 172

Query: 181  EQLFNSCKDVKFGTLNTRAMDFVGGGAQNYTEWFAFLGHRANLSMPGSPYAIAFQSIISD 360
            + L+ SCKDVKFGT+NTRA+DF+GGGAQN+ +WFAF+G RA  ++PGSPY I F     +
Sbjct: 173  QGLYESCKDVKFGTMNTRALDFIGGGAQNFKDWFAFIGRRAAANLPGSPYTIKFWPSAPE 232

Query: 361  LSGVRPLNATVYSCGDTSLGCSCGDCPSSALCVGSLQPAPHVKRSCSVKIASLKVKCLDF 540
            LSG+ P+N + YSC D SLGCSCGDC SS +C  S  P PH   SCSVK+ SL  KC+DF
Sbjct: 233  LSGMIPMNVSAYSCADGSLGCSCGDCTSSPVC-SSTAPPPHKSSSCSVKMGSLNAKCVDF 291

Query: 541  SLVIVYLFLLPAFLLWGSWYQKKKADPS-RTEPFFNANGGNS-----SDKQENRSPQISE 702
            +L I+Y+ L+  F  WG +++K++   S R +P  NA  G+        K+EN   Q+  
Sbjct: 292  ALAILYIILVSLFFGWGFFHRKRERSRSFRMKPLVNAMDGSELHSVERQKEENLPMQVQM 351

Query: 703  -AVPSVIKANRPSVVQLYLSSFFRKYGNFISRHPTXXXXXXXXXXXXXXXXXIRFKVETR 879
               P      + S+VQ Y+S+F+RKYG +++R+PT                 IRF+VETR
Sbjct: 352  LGTPRTRNRIQLSIVQGYMSNFYRKYGKWVARNPTLVLSLSMALVLLLCLGLIRFEVETR 411

Query: 880  PEKLWVGPGSKAAKEKLYFDSHLAPFYRIEQFILANISASNGENPPNIVTEENVKLLFQI 1059
            PEKLWVGPGS+AA+EKL+FDSHLAPFYRIE+ ILA I  +   N P+IVTE N+KLLF+I
Sbjct: 412  PEKLWVGPGSRAAEEKLFFDSHLAPFYRIEELILATIPDTTHGNLPSIVTESNIKLLFEI 471

Query: 1060 QKKVDDLHANYSGSVVSLPDICLKPLGNDCATQSILQYFQMDPQNYDAYGGLAHLQYCFE 1239
            QKK+D L ANYSGS++SL DIC+KPLG DCATQS+LQYF+MDP+N+D +GG+ H++YCF+
Sbjct: 472  QKKIDGLRANYSGSMISLTDICMKPLGQDCATQSVLQYFKMDPKNFDDFGGVEHVKYCFQ 531

Query: 1240 HFSSEKSCLSAFSAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDKTSSEYRNAVAWE 1419
            H++S +SC+SAF  PLDPSTALGGFSGNNYSEASAFV+TYPVNN +D+  +E + AVAWE
Sbjct: 532  HYTSTESCMSAFKGPLDPSTALGGFSGNNYSEASAFVVTYPVNNAVDREGNETKKAVAWE 591

Query: 1420 KAFVQLMKDEIIPMVXXXXXXXXXXXXXXXXXXXKRESTADAITIFISYLVMFAYISVTL 1599
            KAFVQL KDE++PMV                   KRESTADAITI ISYLVMFAYIS+TL
Sbjct: 592  KAFVQLAKDELLPMVQSKNLTLAFSSESSIEEELKRESTADAITIVISYLVMFAYISLTL 651

Query: 1600 GNRHHLSSIFXXXXXXXXXXXXXXXXXXXXXXXXFYSAIGVKSTLIIMEVIPFLVLAVGV 1779
            G+  HLSS +                        F+SAIGVKSTLIIMEVIPFLVLAVGV
Sbjct: 652  GDTPHLSSFYISSKVLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVGV 711

Query: 1780 DNMCILVHTIKRQPLELLLEERISSALADVGPSITLASLSEVLAFAVGSFIPMPACRVFS 1959
            DNMCILVH +KRQ LEL LE RIS+AL +VGPSITLASLSEVLAFAVGSFIPMPACRVFS
Sbjct: 712  DNMCILVHAVKRQQLELPLETRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFS 771

Query: 1960 MXXXXXXXXXXXXQVTAFVSLIIFDFLRA 2046
            M            Q+TAFV+LI+FDFLRA
Sbjct: 772  MFAALAVLLDFLLQITAFVALIVFDFLRA 800



 Score =  149 bits (375), Expect = 1e-32
 Identities = 70/97 (72%), Positives = 85/97 (87%)
 Frame = +2

Query: 2099 LRGVKIIVILVFSGFAFASIALCTRVQPGLEQKIVLPRDSYLQNYFDDLAKYLRVGPPLY 2278
            L GVKI VI +F  F  ASIALCTR++PGLEQKIVLPRDSYLQ YF++++++LR+GPPLY
Sbjct: 846  LWGVKIAVISLFVAFTLASIALCTRIEPGLEQKIVLPRDSYLQGYFNNISEHLRIGPPLY 905

Query: 2279 FVVKDFNYSLESRNTNQICSISQCDSNSLLNEITKAS 2389
            FVVK++NYS ESR TNQ+CSISQCDSNSLLNE+  +S
Sbjct: 906  FVVKNYNYSSESRQTNQLCSISQCDSNSLLNEVELSS 942


>ref|XP_018836418.1| PREDICTED: Niemann-Pick C1 protein-like isoform X1 [Juglans regia]
          Length = 1302

 Score =  837 bits (2161), Expect = 0.0
 Identities = 420/688 (61%), Positives = 507/688 (73%), Gaps = 6/688 (0%)
 Frame = +1

Query: 1    QQAIPLLVSCPACLRNFLNLFCELSCSPDQSLFINVTSVKKVNDSMTVDMIDYFITPYFG 180
            QQAIP LV CPACLRNFLNLFCEL+CSP+QSLFINVTSV KVN ++TVD ID++IT  FG
Sbjct: 118  QQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVSKVNSNLTVDGIDFYITDAFG 177

Query: 181  EQLFNSCKDVKFGTLNTRAMDFVGGGAQNYTEWFAFLGHRANLSMPGSPYAIAFQSIISD 360
            E L++SCKDVK+GT+N+RA++F+G GAQN+ EWFAF+G RA L++PGSPYAI F S  ++
Sbjct: 178  EGLYDSCKDVKYGTMNSRALEFIGAGAQNFKEWFAFIGRRAGLNLPGSPYAIVFHSNAAE 237

Query: 361  LSGVRPLNATVYSCGDTSLGCSCGDCPSSALCVGSLQPAPHVKRSCSVKIASLKVKCLDF 540
             SG++P+N T YSCGD SL CSCGDC SS +C  +  PA H + SCSV+I SLK KC+DF
Sbjct: 238  SSGMKPMNVTSYSCGDISLRCSCGDCRSSPVCTNTSPPATHKRGSCSVRIGSLKAKCIDF 297

Query: 541  SLVIVYLFLLPAFLLWGSWYQKKKADP-SRTEPFFNANGGN-----SSDKQENRSPQISE 702
            +L I+Y+ L+  FL WG ++  ++ +P SRT+P  NA         +  K EN   Q+ E
Sbjct: 298  ALAILYVVLVSIFLGWGLFHHTRERNPHSRTKPVLNAMDVGQLHSVNRKKDENFPMQMLE 357

Query: 703  AVPSVIKANRPSVVQLYLSSFFRKYGNFISRHPTXXXXXXXXXXXXXXXXXIRFKVETRP 882
              P +    R SVVQ Y+S+F+R+YG +++R+PT                 IRFKVETRP
Sbjct: 358  DSPQIGNGVRLSVVQGYMSNFYRRYGTWVARNPTLVLCSSLAIVLMLCLGLIRFKVETRP 417

Query: 883  EKLWVGPGSKAAKEKLYFDSHLAPFYRIEQFILANISASNGENPPNIVTEENVKLLFQIQ 1062
            EKLWVGPGS+AA+EK +FDSHLAPFYRIEQ ILA I  +     P+IVTE N+KLLF+IQ
Sbjct: 418  EKLWVGPGSRAAEEKQFFDSHLAPFYRIEQIILATIPDAMDGRSPSIVTESNIKLLFEIQ 477

Query: 1063 KKVDDLHANYSGSVVSLPDICLKPLGNDCATQSILQYFQMDPQNYDAYGGLAHLQYCFEH 1242
            KKVD +HANYSGS++SL DIC+KPL  DCATQS+LQYF+MDP+NYD YGG+ HL+YCF+H
Sbjct: 478  KKVDGIHANYSGSMISLSDICMKPLDQDCATQSVLQYFKMDPENYDNYGGVEHLEYCFQH 537

Query: 1243 FSSEKSCLSAFSAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDKTSSEYRNAVAWEK 1422
            +SS   C+SAF APLDPSTALGGF  NNYSEASAF++TYPVNN +DK  +E + AVAWEK
Sbjct: 538  YSSADKCMSAFKAPLDPSTALGGFPANNYSEASAFIVTYPVNNAIDKEGNETQRAVAWEK 597

Query: 1423 AFVQLMKDEIIPMVXXXXXXXXXXXXXXXXXXXKRESTADAITIFISYLVMFAYISVTLG 1602
            AF+QL+KDE++P+                    KRESTADAITI ISYLVMFAYIS+TLG
Sbjct: 598  AFIQLVKDELLPLAQSQNLTLSFSSESSIEEELKRESTADAITILISYLVMFAYISLTLG 657

Query: 1603 NRHHLSSIFXXXXXXXXXXXXXXXXXXXXXXXXFYSAIGVKSTLIIMEVIPFLVLAVGVD 1782
            +   LSS +                        F+S IGVKSTLIIMEVIPFLVLAVGVD
Sbjct: 658  DTPRLSSFYISSKMLLGFSGVILVVLSVLASVGFFSVIGVKSTLIIMEVIPFLVLAVGVD 717

Query: 1783 NMCILVHTIKRQPLELLLEERISSALADVGPSITLASLSEVLAFAVGSFIPMPACRVFSM 1962
            NMCILVH +KRQPLEL LE RIS+AL +VGPSITLASLSEVLAFAVGSFIPMPACRVFSM
Sbjct: 718  NMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSM 777

Query: 1963 XXXXXXXXXXXXQVTAFVSLIIFDFLRA 2046
                        QVTAFV+LI+FDFLRA
Sbjct: 778  FAALAVLLDFLLQVTAFVALIVFDFLRA 805



 Score =  573 bits (1476), Expect = 0.0
 Identities = 277/389 (71%), Positives = 323/389 (83%)
 Frame = +2

Query: 2099 LRGVKIIVILVFSGFAFASIALCTRVQPGLEQKIVLPRDSYLQNYFDDLAKYLRVGPPLY 2278
            L GVKI+VI VF G+A ASIALCTR++PGLEQKIVLPRDSYLQ Y +D+++YLR+GPPLY
Sbjct: 851  LWGVKIVVISVFLGYALASIALCTRIEPGLEQKIVLPRDSYLQGYLNDVSEYLRIGPPLY 910

Query: 2279 FVVKDFNYSLESRNTNQICSISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWL 2458
            FVVK++NYS ESR+TNQ+CSISQCDS+SLLNEI + SL P SSYIAKPAASWLDDFL+W+
Sbjct: 911  FVVKNYNYSSESRHTNQLCSISQCDSDSLLNEIARESLTPDSSYIAKPAASWLDDFLLWM 970

Query: 2459 SPEAFSCCRKFLNGSYXXXXXXXXXXXXXXGLCNMGTTCKDCTTCYRYSDLHDGRPSTMD 2638
            SPEAF CCRKF N SY                C +   CKDCTTC+R+SDLH+ RPST+ 
Sbjct: 971  SPEAFGCCRKFTNQSYCPPDDQPPCCSPNEVSCGLDGVCKDCTTCFRHSDLHNDRPSTVQ 1030

Query: 2639 FKVKLPWFLNALPSSNCAKGGKGAYTSSVDLSGYESGIIQASSFRTYHTPLNRQIDYVNS 2818
            FK KLPWFLN+LPS+ CAKGG GAYTSSV+L GYE+ +I ASSFRTYHTPLNRQIDYVNS
Sbjct: 1031 FKEKLPWFLNSLPSAACAKGGHGAYTSSVELKGYENSVIPASSFRTYHTPLNRQIDYVNS 1090

Query: 2819 MKAALDFXXXXXXXXXMEIFPYSVFYIFFEQYLDIWRTALINISIGLGAVFVVCLVLTGS 2998
            M+AA +F         +EIFPYSVFY+FFEQYLDIWRTALIN++I +GAVF+VCLV+T S
Sbjct: 1091 MRAAREFTSKISDSLKIEIFPYSVFYMFFEQYLDIWRTALINLAIAIGAVFIVCLVITCS 1150

Query: 2999 IWVSTIILAVLVMIVIDMLGLMAILGIQLNAISVVNLVMSIGIAVEFCVHITHAFLLSSG 3178
             W S II  VL MI++D++G+MAIL IQLNA+SVVNLVMS+GIAVEFCVH+THAF +SSG
Sbjct: 1151 FWSSAIIFLVLAMILVDLMGVMAILDIQLNAVSVVNLVMSVGIAVEFCVHMTHAFSVSSG 1210

Query: 3179 DRETRMKMALSTMGASVFSGITLTKLVGV 3265
            D+E R K AL TMGASVFSGITLTKLVGV
Sbjct: 1211 DKEQRTKEALGTMGASVFSGITLTKLVGV 1239


>gb|PON90466.1| Niemann-Pick C type protein [Trema orientalis]
          Length = 1292

 Score =  832 bits (2148), Expect = 0.0
 Identities = 421/687 (61%), Positives = 508/687 (73%), Gaps = 6/687 (0%)
 Frame = +1

Query: 1    QQAIPLLVSCPACLRNFLNLFCELSCSPDQSLFINVTSVKKVNDSMTVDMIDYFITPYFG 180
            QQAIP LV CPACLRNFLNLFCEL+CSP+QSLFINVTSV KVN+S+TVD ID++IT  FG
Sbjct: 120  QQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVSKVNNSLTVDGIDFYITDAFG 179

Query: 181  EQLFNSCKDVKFGTLNTRAMDFVGGGAQNYTEWFAFLGHRANLSMPGSPYAIAFQSIISD 360
            E L++SC DVKFGT+N+RA++F+G GA+N+ EWFAF+G RA  ++PGSPYAIAFQS IS+
Sbjct: 180  EGLYDSCNDVKFGTMNSRALEFIGAGAKNFKEWFAFIGRRAPANVPGSPYAIAFQSSISE 239

Query: 361  LSGVRPLNATVYSCGDTSLGCSCGDCPSSALCVGSLQPAPHVKRSCSVKIASLKVKCLDF 540
             SG++P+N + YSCGD SLGCSCGDCP+S +C  S+ P    + SC+V+I SLK KC+D 
Sbjct: 240  SSGMKPMNVSTYSCGDVSLGCSCGDCPASPVCSSSVPPPLQKEGSCTVRIGSLKAKCIDI 299

Query: 541  SLVIVYLFLLPAFLLWGSWYQKKKADP-SRTEPFFNANGGN-----SSDKQENRSPQISE 702
            ++ I+Y+ L+ AFL W  +Y   K  P SRT+P +NA  G      +  K+EN S Q+ E
Sbjct: 300  AVAILYIILVSAFLGWRLFYLNGKKKPASRTKPVWNAMEGGELHSVNRQKEENPSIQMLE 359

Query: 703  AVPSVIKANRPSVVQLYLSSFFRKYGNFISRHPTXXXXXXXXXXXXXXXXXIRFKVETRP 882
              P +    + SVVQ Y+S+FFR YG +++++P                  IRFKVETRP
Sbjct: 360  DDPQIRNGVQLSVVQGYMSNFFRIYGTWVAKNPIIVLCSSLAIVLILCLGLIRFKVETRP 419

Query: 883  EKLWVGPGSKAAKEKLYFDSHLAPFYRIEQFILANISASNGENPPNIVTEENVKLLFQIQ 1062
            EKLWVGPGSKAA+EK +FDSHLAPFYRIEQ ILA I   NG++ P+IVTE N+KLLF+IQ
Sbjct: 420  EKLWVGPGSKAAEEKQFFDSHLAPFYRIEQLILATIPDDNGKS-PSIVTENNIKLLFEIQ 478

Query: 1063 KKVDDLHANYSGSVVSLPDICLKPLGNDCATQSILQYFQMDPQNYDAYGGLAHLQYCFEH 1242
            KKVD L AN+SGS +SL DIC+KPL  DCATQS+LQYF+MDP NYD +GG+ HL+YCFEH
Sbjct: 479  KKVDGLRANFSGSAISLSDICMKPLDQDCATQSVLQYFKMDPDNYDNFGGVEHLKYCFEH 538

Query: 1243 FSSEKSCLSAFSAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDKTSSEYRNAVAWEK 1422
            +SS   C+SAF APLDPSTALGGFSGNNYSEASAF++TYPVNN +DK  +E   AVAWEK
Sbjct: 539  YSSADKCMSAFKAPLDPSTALGGFSGNNYSEASAFIVTYPVNNAVDKRGNESEKAVAWEK 598

Query: 1423 AFVQLMKDEIIPMVXXXXXXXXXXXXXXXXXXXKRESTADAITIFISYLVMFAYISVTLG 1602
            A++Q+ KDE++ MV                   KREST DAITI ISYLVMFAYIS+TLG
Sbjct: 599  AYIQMAKDELLQMVQSKNLTLSFSSESSIEEELKRESTTDAITIVISYLVMFAYISLTLG 658

Query: 1603 NRHHLSSIFXXXXXXXXXXXXXXXXXXXXXXXXFYSAIGVKSTLIIMEVIPFLVLAVGVD 1782
            +   LSS +                        F+SAIGVKSTLIIMEVIPFLVLAVGVD
Sbjct: 659  DTPRLSSFYISSKVLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVGVD 718

Query: 1783 NMCILVHTIKRQPLELLLEERISSALADVGPSITLASLSEVLAFAVGSFIPMPACRVFSM 1962
            NMCILVH +KRQP+EL LEERIS+AL +VGPSITLAS++EVLAFAVGSFIPMPACRVFSM
Sbjct: 719  NMCILVHAVKRQPMELPLEERISNALVEVGPSITLASIAEVLAFAVGSFIPMPACRVFSM 778

Query: 1963 XXXXXXXXXXXXQVTAFVSLIIFDFLR 2043
                        QVTAFV+LI FDFLR
Sbjct: 779  FAALAVLLDFLLQVTAFVALIAFDFLR 805



 Score =  525 bits (1351), Expect = e-162
 Identities = 264/392 (67%), Positives = 306/392 (78%), Gaps = 3/392 (0%)
 Frame = +2

Query: 2099 LRGVKIIVILVFSGFAFASIALCTRVQPGLEQKIVLPRDSYLQNYFDDLAKYLRVGPPLY 2278
            L GVKI+VI VF  F  ASIALCTR++PGLEQKIVLP+DSYLQ YF+ +++YLR+GPPLY
Sbjct: 851  LWGVKIVVISVFVAFTLASIALCTRIEPGLEQKIVLPQDSYLQGYFNSVSEYLRIGPPLY 910

Query: 2279 FVVKDFNYSLESRNTNQICSISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWL 2458
            FVVK++NYS ESR+TNQ+CSIS+CDS+SLLNEI KAS  P +SYIAKPAASWLDDFL+W+
Sbjct: 911  FVVKNYNYSSESRHTNQLCSISKCDSDSLLNEIAKASSTPKASYIAKPAASWLDDFLVWI 970

Query: 2459 SPEAFSCCRKFLNGSYXXXXXXXXXXXXXXGLCNMGTTCKDCTTCYRYSDLHDGRPSTMD 2638
            SPEAF CCRKF+N +Y              G C++G  CKDCTTC+R SDL + RPST  
Sbjct: 971  SPEAFGCCRKFINSTYCPPDDQPPCCSSSDGSCSLGGVCKDCTTCFRRSDLQNDRPSTTQ 1030

Query: 2639 FKVKLPWFLNALPSSNCAKGGKGAYTSSVDLSGYESGIIQASSFRTYHTPLNRQIDYVNS 2818
            FK KLPWFLNALPS+ CAKGG GAYT+SV+L  YESGIIQASSFRTYHTPLN+QIDYVNS
Sbjct: 1031 FKDKLPWFLNALPSAACAKGGHGAYTTSVELKDYESGIIQASSFRTYHTPLNKQIDYVNS 1090

Query: 2819 MKAALDFXXXXXXXXXMEIFPYSVFYIFFEQYLDIWRTALINISIGLGAVFVVCLVLTGS 2998
            M+AA +F         +EIFPYSVFY+FFEQYLDIW+TALIN+SI +G+           
Sbjct: 1091 MRAAREFSSRISDSLKVEIFPYSVFYMFFEQYLDIWKTALINLSIAIGS----------- 1139

Query: 2999 IWVSTIILAVLVMIVIDML---GLMAILGIQLNAISVVNLVMSIGIAVEFCVHITHAFLL 3169
                   L  LVM   DM    G+MAIL IQLNAISVVNLVMS+GIAVEFCVH+THAF +
Sbjct: 1140 -------LCYLVMSPYDMTNLQGVMAILRIQLNAISVVNLVMSVGIAVEFCVHMTHAFSV 1192

Query: 3170 SSGDRETRMKMALSTMGASVFSGITLTKLVGV 3265
            SSGD+  R+K AL TMGASVFSGITLTKLVGV
Sbjct: 1193 SSGDKNQRVKEALGTMGASVFSGITLTKLVGV 1224


>gb|KDO85104.1| hypothetical protein CISIN_1g000762mg [Citrus sinensis]
          Length = 1133

 Score =  826 bits (2133), Expect = 0.0
 Identities = 417/689 (60%), Positives = 506/689 (73%), Gaps = 7/689 (1%)
 Frame = +1

Query: 1    QQAIPLLVSCPACLRNFLNLFCELSCSPDQSLFINVTSVKKVNDSMTVDMIDYFITPYFG 180
            QQAIP LV CPACLRNFLNLFCEL+CSP+QSLFINVTSV KV++++TVD IDY+IT  FG
Sbjct: 113  QQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVSKVSNNLTVDGIDYYITDTFG 172

Query: 181  EQLFNSCKDVKFGTLNTRAMDFVGGGAQNYTEWFAFLGHRANLSMPGSPYAIAFQSIISD 360
            + L+ SCKDVKFGT+NTRA+DF+GGGAQN+ +WFAF+G RA  ++PGSPY I F     +
Sbjct: 173  QGLYESCKDVKFGTMNTRALDFIGGGAQNFKDWFAFIGRRAAANLPGSPYTIKFWPSAPE 232

Query: 361  LSGVRPLNATVYSCGDTSLGCSCGDCPSSALCVGSLQPAPHVKRSCSVKIASLKVKCLDF 540
            LSG+ P+N + YSC D SLGCSCGDC SS +C  S  P PH   SCSVK+ SL  KC+DF
Sbjct: 233  LSGMIPMNVSAYSCADGSLGCSCGDCTSSPVC-SSTAPPPHKSSSCSVKMGSLNAKCVDF 291

Query: 541  SLVIVYLFLLPAFLLWGSWYQKKKADPS-RTEPFFNANGGNS-----SDKQENRSPQISE 702
            +L I+Y+ L+  F  WG +++K++   S R +P  NA  G+        K+EN   Q+  
Sbjct: 292  ALAILYIILVSLFFGWGFFHRKRERSRSFRMKPLVNAMDGSELHSVERQKEENLPMQVQM 351

Query: 703  -AVPSVIKANRPSVVQLYLSSFFRKYGNFISRHPTXXXXXXXXXXXXXXXXXIRFKVETR 879
               P      + S+VQ Y+S+F+RKYG +++R+PT                 IRF+VETR
Sbjct: 352  LGTPRTRNRIQLSIVQGYMSNFYRKYGKWVARNPTLVLSLSMALVLLLCLGLIRFEVETR 411

Query: 880  PEKLWVGPGSKAAKEKLYFDSHLAPFYRIEQFILANISASNGENPPNIVTEENVKLLFQI 1059
            PEKLWVGPGS+AA+EKL+FDSHLAPFYRIE+ ILA I  +   N P+IVTE N+KLLF+I
Sbjct: 412  PEKLWVGPGSRAAEEKLFFDSHLAPFYRIEELILATIPDTTHGNLPSIVTESNIKLLFEI 471

Query: 1060 QKKVDDLHANYSGSVVSLPDICLKPLGNDCATQSILQYFQMDPQNYDAYGGLAHLQYCFE 1239
            QKK+D L ANYSGS++SL DIC+KPLG DCATQS+LQYF+MDP+N+D +GG+ H++YCF+
Sbjct: 472  QKKIDGLRANYSGSMISLTDICMKPLGQDCATQSVLQYFKMDPKNFDDFGGVEHVKYCFQ 531

Query: 1240 HFSSEKSCLSAFSAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDKTSSEYRNAVAWE 1419
            H++S +SC+SAF  PLDPSTALGGFSGNNYSEASAFV+TYPVNN +D+  +E + AVAWE
Sbjct: 532  HYTSTESCMSAFKGPLDPSTALGGFSGNNYSEASAFVVTYPVNNAVDREGNETKKAVAWE 591

Query: 1420 KAFVQLMKDEIIPMVXXXXXXXXXXXXXXXXXXXKRESTADAITIFISYLVMFAYISVTL 1599
            KAFVQL KDE++PMV                   KRESTADAITI ISYLVMFAYIS+TL
Sbjct: 592  KAFVQLAKDELLPMVQSKNLTLAFSSESSIEEELKRESTADAITIVISYLVMFAYISLTL 651

Query: 1600 GNRHHLSSIFXXXXXXXXXXXXXXXXXXXXXXXXFYSAIGVKSTLIIMEVIPFLVLAVGV 1779
            G+  HLSS +                        F+SAIGVKSTLIIMEVIPFLVLAVGV
Sbjct: 652  GDTPHLSSFYISSKVLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVGV 711

Query: 1780 DNMCILVHTIKRQPLELLLEERISSALADVGPSITLASLSEVLAFAVGSFIPMPACRVFS 1959
            DNMCILVH +KRQ LEL LE RIS+AL +VGPSITLASLSEVLAFAVGSFIPMPACRVFS
Sbjct: 712  DNMCILVHAVKRQQLELPLETRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFS 771

Query: 1960 MXXXXXXXXXXXXQVTAFVSLIIFDFLRA 2046
            M            Q+TAFV+LI+FDFLRA
Sbjct: 772  MFAALAVLLDFLLQITAFVALIVFDFLRA 800



 Score =  429 bits (1102), Expect = e-128
 Identities = 202/288 (70%), Positives = 235/288 (81%)
 Frame = +2

Query: 2099 LRGVKIIVILVFSGFAFASIALCTRVQPGLEQKIVLPRDSYLQNYFDDLAKYLRVGPPLY 2278
            L GVKI VI +F  F  ASIALCTR++PGLEQKIVLPRDSYLQ YF++++++LR+GPPLY
Sbjct: 846  LWGVKIAVISLFVAFTLASIALCTRIEPGLEQKIVLPRDSYLQGYFNNISEHLRIGPPLY 905

Query: 2279 FVVKDFNYSLESRNTNQICSISQCDSNSLLNEITKASLVPASSYIAKPAASWLDDFLIWL 2458
            FVVK++NYS ESR TNQ+CSISQCDSNSLLNEI++ASL+P SSYIAKPAASWLDDFL+W+
Sbjct: 906  FVVKNYNYSSESRQTNQLCSISQCDSNSLLNEISRASLIPQSSYIAKPAASWLDDFLVWI 965

Query: 2459 SPEAFSCCRKFLNGSYXXXXXXXXXXXXXXGLCNMGTTCKDCTTCYRYSDLHDGRPSTMD 2638
            SPEAF CCRKF NGSY                C     CKDCTTC+ +SDL   RPST+ 
Sbjct: 966  SPEAFGCCRKFTNGSYCPPDDQPPCCPSGQSSCGSAGVCKDCTTCFHHSDLLKDRPSTIQ 1025

Query: 2639 FKVKLPWFLNALPSSNCAKGGKGAYTSSVDLSGYESGIIQASSFRTYHTPLNRQIDYVNS 2818
            FK KLPWFLNALPS++CAKGG GAYT+SVDL GYE+GI+QASSFRTYHTPLNRQIDYVNS
Sbjct: 1026 FKEKLPWFLNALPSASCAKGGHGAYTNSVDLKGYENGIVQASSFRTYHTPLNRQIDYVNS 1085

Query: 2819 MKAALDFXXXXXXXXXMEIFPYSVFYIFFEQYLDIWRTALINISIGLG 2962
            M+AA +F         MEIFPYSVFY++FEQYLDIWRTALIN++I +G
Sbjct: 1086 MRAAREFSSRVSDSLQMEIFPYSVFYMYFEQYLDIWRTALINLAIAIG 1133