BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Catharanthus22_contig00011739
         (3494 letters)

Database: ./nr 
           37,332,560 sequences; 13,225,080,153 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]                1529   0.0  
dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]               1162   0.0  
dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]      1154   0.0  
dbj|BAK32961.1| topoisomerase I [Ophiorrhiza ridleyana]              1146   0.0  
dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. g...  1144   0.0  
dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]            1143   0.0  
dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]            1137   0.0  
dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]                 1135   0.0  
dbj|BAK32956.1| topoisomerase I [Ophiorrhiza fucosa]                 1132   0.0  
dbj|BAK32959.1| topoisomerase I [Ophiorrhiza plumbea]                1123   0.0  
dbj|BAK32963.1| topoisomerase I [Ophiorrhiza sp. 35]                 1116   0.0  
dbj|BAK32957.1| topoisomerase I [Ophiorrhiza harrisiana]             1104   0.0  
dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]              1103   0.0  
gb|EOY12189.1| DNA topoisomerase I alpha isoform 1 [Theobroma ca...  1018   0.0  
ref|XP_006364175.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...  1003   0.0  
ref|XP_006474977.1| PREDICTED: DNA topoisomerase 1-like isoform ...   993   0.0  
ref|XP_006452479.1| hypothetical protein CICLE_v10007398mg [Citr...   991   0.0  
ref|XP_002300344.1| DNA topoisomerase family protein [Populus tr...   976   0.0  
ref|XP_002529020.1| DNA topoisomerase type I, putative [Ricinus ...   972   0.0  
ref|XP_002317355.1| DNA topoisomerase family protein [Populus tr...   964   0.0  

>dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]
          Length = 910

 Score = 1529 bits (3958), Expect = 0.0
 Identities = 784/910 (86%), Positives = 786/910 (86%)
 Frame = -3

Query: 3240 MAVEACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDSR 3061
            MAVEACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDSR
Sbjct: 1    MAVEACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDSR 60

Query: 3060 PANGESSSGQKGRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXP 2881
            PANGESSSGQKGRM                                             P
Sbjct: 61   PANGESSSGQKGRMVPPSKPSQVKSPLSSPPSKPSQVKSPLSSPKVSTSSAKKSPVSSLP 120

Query: 2880 ANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSASS 2701
            ANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSASS
Sbjct: 121  ANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSASS 180

Query: 2700 SKGNTNQVSKEGSKPENEDSDDEKPLSSRFPLKSGVGESTSNAYDSDDDKPLAKKLQHNG 2521
            SKGNTNQVSKEGSKPENEDSDDEKPLSSRFPLKSGVGESTS AYDSDDDKPLAKKLQHNG
Sbjct: 181  SKGNTNQVSKEGSKPENEDSDDEKPLSSRFPLKSGVGESTSKAYDSDDDKPLAKKLQHNG 240

Query: 2520 SAMRDGQPNKYSNMSNKRPPGEIKSSNQLSVKKPKLSSVTAPTNKKQASVKPEPKAEXXX 2341
            SAMRDGQPNKYSNMSNKRPPG+IKSSNQLSVKKPKLSSVTAPTNKKQASVKPEPKAE   
Sbjct: 241  SAMRDGQPNKYSNMSNKRPPGDIKSSNQLSVKKPKLSSVTAPTNKKQASVKPEPKAEDDD 300

Query: 2340 XDHLPISQRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXS 2161
             DHLPISQRI                                                 S
Sbjct: 301  DDHLPISQRIKKSPTSESKSSSIKKTTKVVSSSVKKVNKKSKKVMKNSKYSKSSKVPPSS 360

Query: 2160 GEGKKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMNKPR 1981
            GEGKKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMNKPR
Sbjct: 361  GEGKKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMNKPR 420

Query: 1980 FKENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSXXXXXXXXXXXXXXXXXXXXXXXX 1801
            FKENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQS                        
Sbjct: 421  FKENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSEKEKKKQMTTEEKKALKEEKLKQE 480

Query: 1800 XKYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCDITINIGKDAPIPEC 1621
             KYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCDITINIGKDAPIPEC
Sbjct: 481  EKYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCDITINIGKDAPIPEC 540

Query: 1620 PVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGLSDKEKYEKARLLKDY 1441
            PVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGLSDKEKYEKARLLKDY
Sbjct: 541  PVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGLSDKEKYEKARLLKDY 600

Query: 1440 IQGIRAAYTKNFASKDPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP 1261
            IQGIRAAYTK+FASKDPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP
Sbjct: 601  IQGIRAAYTKDFASKDPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP 660

Query: 1260 VPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSSDLFDLLDTSKLNAHLKE 1081
            VPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSSDLFDLLDTSKLNAHLKE
Sbjct: 661  VPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSSDLFDLLDTSKLNAHLKE 720

Query: 1080 LMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSH 901
            LMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSH
Sbjct: 721  LMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSH 780

Query: 900  SAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPKRNLNPESLEKKIAQT 721
            SAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPKRNLNPESLEKKIAQT
Sbjct: 781  SAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPKRNLNPESLEKKIAQT 840

Query: 720  NAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTW 541
            NAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTW
Sbjct: 841  NAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTW 900

Query: 540  AMDVDPSFRF 511
            AMDVDPSFRF
Sbjct: 901  AMDVDPSFRF 910


>dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]
          Length = 927

 Score = 1162 bits (3006), Expect = 0.0
 Identities = 626/948 (66%), Positives = 682/948 (71%), Gaps = 38/948 (4%)
 Frame = -3

Query: 3240 MAVEACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDSR 3061
            MAVEAC TPNL +DM++D+ P++FKR+N ASKQ+Q NSE +K+S QK  GQS     D R
Sbjct: 1    MAVEAC-TPNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 59

Query: 3060 PANGESSSGQKGRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXP 2881
            PANGESSS QKGR+                                              
Sbjct: 60   PANGESSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPG-------------- 105

Query: 2880 ANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSASS 2701
            ANSKPS S +   K  N HKS+    E K  P   A+   ++SE SDD KPLS R    S
Sbjct: 106  ANSKPSASATSTAKQQNHHKSSAAFIEPK--PSVPAAKANSNSESSDDEKPLSARTFGCS 163

Query: 2700 SKGNTNQVSKEGSKP---------ENEDSDDEKPLSSRFPLKSGVGESTSNAYDSDDDKP 2548
            SKG +N  +KEG            E+EDS+DEKPLS RF  KS +GESTS +YDSD+ KP
Sbjct: 164  SKGKSNHANKEGGDSCSIRRRVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKP 223

Query: 2547 LAKKLQHNGSAMRDGQPNKYSNMSNKRPPGEIKSSNQLSVKKPKLSS-VTAPTN------ 2389
            LA K+Q NGS  RDG  NK +++SNKRPPGE+KS NQ SVKKPKLSS +T+ +N      
Sbjct: 224  LAAKVQQNGSVSRDGPMNKSASLSNKRPPGEVKSLNQSSVKKPKLSSPITSISNKQAAVK 283

Query: 2388 --------------------KKQASVKPEPKAEXXXXDHLPISQRIXXXXXXXXXXXXXX 2269
                                KK  +   +PK E     ++PI+QRI              
Sbjct: 284  PEPEPKAEDDDDNIPLSQRGKKSQAATSKPKDEDDD--NVPIAQRIKKSPASVSKSSAPV 341

Query: 2268 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXS-GEGKKWNKLEHNGVIFPPPYKPH 2092
                                                 GEG+KW  L HNGVIFPPPY PH
Sbjct: 342  KKASTVVSPSLKKVNKNSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYNPH 401

Query: 2091 GIKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLE 1912
            G+KMLYK +P+ LTPEQEEVATMFAVMLDTDYMNKPRFKENFF DWKK+LGKNH IQNLE
Sbjct: 402  GVKMLYKRQPITLTPEQEEVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLE 461

Query: 1911 NCDFSPIYEWHQSXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAWVDGKKEKVGNFRVEPP 1732
            +CDF PIYEWHQ                          KYMWA VDG KEKVGNFRVEPP
Sbjct: 462  DCDFGPIYEWHQQEKEKKKQMTTEEKKALKEDKLQQEEKYMWAIVDGVKEKVGNFRVEPP 521

Query: 1731 GLFRGRGEHPKMGKLKKRIRPCDITINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWN 1552
            GLFRGRGEHPKMGKLKKRIRP DITINIGKDAPIPECP+PGERWKEVR+DNTVTWLAFW 
Sbjct: 522  GLFRGRGEHPKMGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWI 581

Query: 1551 DPINPKEFKYVFLAASSTLKGLSDKEKYEKARLLKDYIQGIRAAYTKNFAS-KDPTKKQI 1375
            DPIN KEFKYVFLAASSTLKG SDKEKYEKARLLKDYI GIRAAYTK+F + KDP KKQI
Sbjct: 582  DPINQKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQI 641

Query: 1374 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEV 1195
            AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEV
Sbjct: 642  AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEV 701

Query: 1194 EVEAAVFKAIQQFRSGKEGSSDLFDLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 1015
            +VE AVFKAIQQFRSGKEGS DLFD LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM
Sbjct: 702  QVEPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 761

Query: 1014 LSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELK 835
            LS+ETKGG+VAEKVVVYQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EELK
Sbjct: 762  LSKETKGGEVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTAMEELK 821

Query: 834  SDLSRVKKGKPPLKSKNADGKPKRNLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVAL 655
            +DLSRVKKGKPP  SK ADGKPKRNLNPE+LE+K+AQ NAKIEKMERDKETKEDLKTVAL
Sbjct: 822  TDLSRVKKGKPP--SKGADGKPKRNLNPEALERKMAQINAKIEKMERDKETKEDLKTVAL 879

Query: 654  GTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPSFRF 511
            GTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF W+MDVDPSFRF
Sbjct: 880  GTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWSMDVDPSFRF 927


>dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]
          Length = 925

 Score = 1154 bits (2984), Expect = 0.0
 Identities = 623/946 (65%), Positives = 678/946 (71%), Gaps = 36/946 (3%)
 Frame = -3

Query: 3240 MAVEACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDSR 3061
            MAVEAC T NL +DM++D  P++FKR+  A KQ+Q NSE +K+S QK+DGQS     D R
Sbjct: 1    MAVEACTT-NLMEDMEDDGGPVIFKRSKPAPKQNQANSEKKKLSLQKQDGQSAVHTSDVR 59

Query: 3060 PANGESSSGQKGRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXP 2881
            PANGESSS QKGR+                                              
Sbjct: 60   PANGESSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPG-------------- 105

Query: 2880 ANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSASS 2701
            ANSKPS S +   K  N HKS+    E K  P   A+   ++SE SDD KPLS R    S
Sbjct: 106  ANSKPSASATSTAKQQNHHKSSAAFIEPK--PSVPAAKANSNSESSDDEKPLSARTFGCS 163

Query: 2700 SKGNTNQVSKEGSKP---------ENEDSDDEKPLSSRFPLKSGVGESTSNAYDSDDDKP 2548
            SKG +N  +KEG            E+EDS+DEKPLS RF  KS +GESTS +YDSD+ KP
Sbjct: 164  SKGKSNHANKEGGDSCSIRRPVIEESEDSEDEKPLSCRFTSKSSLGESTSKSYDSDEKKP 223

Query: 2547 LAKKLQHNGSAMRDGQPNKYSNMSNKRPPGEIKSSNQLSVKKPKLSS-VTAPTNK----- 2386
            LA K+Q NGSA RDG  NK +++SNKRPPGE KS NQ SVKKPKLSS +T+ +NK     
Sbjct: 224  LAAKVQQNGSASRDGPMNKSASLSNKRPPGEAKSLNQSSVKKPKLSSPITSISNKQAAVK 283

Query: 2385 -------------------KQASVKPEPKAEXXXXDHLPISQRIXXXXXXXXXXXXXXXX 2263
                               K  S   +PK +     ++PISQRI                
Sbjct: 284  PEPKAEDDDDNIPLSQRGKKSQSATSKPKDDDDD--NVPISQRIKKSPASVSKSSVPVKK 341

Query: 2262 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXS-GEGKKWNKLEHNGVIFPPPYKPHGI 2086
                                               GEG+KW  L HNGVIFPPPYKPHG+
Sbjct: 342  ASTVVSSSLKKVNKNSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV 401

Query: 2085 KMLYKGKPVDLTPEQEEVATMFAVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLENC 1906
            KMLYK +P+ LTPEQEEVATMFAVMLDTDYMNKP FKENFF DWKKILGKNH+IQNLE+C
Sbjct: 402  KMLYKRQPITLTPEQEEVATMFAVMLDTDYMNKPCFKENFFSDWKKILGKNHMIQNLEDC 461

Query: 1905 DFSPIYEWHQSXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAWVDGKKEKVGNFRVEPPGL 1726
            DF PIYEWHQ                          KYMWA VDG KEKVGNFRVEPPGL
Sbjct: 462  DFGPIYEWHQQEKEKKKQMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGL 521

Query: 1725 FRGRGEHPKMGKLKKRIRPCDITINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDP 1546
            FRGRGEHPKMGKLKKRIRP DITINIGKDAPIPECP+PGERWKEVR+ NTVTWLA+WNDP
Sbjct: 522  FRGRGEHPKMGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNGNTVTWLAYWNDP 581

Query: 1545 INPKEFKYVFLAASSTLKGLSDKEKYEKARLLKDYIQGIRAAYTKNFAS-KDPTKKQIAV 1369
            IN KEFKYVFLAASSTLKG SDKEKYEKARLLKDYI GIRAAYTK+F + KDP KKQIAV
Sbjct: 582  INQKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAV 641

Query: 1368 ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEV 1189
            ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEV+V
Sbjct: 642  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQV 701

Query: 1188 EAAVFKAIQQFRSGKEGSSDLFDLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS 1009
            E AVFKAIQQFRSGKEGS DLFD LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS
Sbjct: 702  EPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS 761

Query: 1008 RETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELKSD 829
            +ETKGG+VAE VVVYQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EELK+D
Sbjct: 762  KETKGGEVAENVVVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTD 821

Query: 828  LSRVKKGKPPLKSKNADGKPKRNLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGT 649
            LSR KKGKPP  +K ADGK KRNLNPE+LE+KI QTNAKIEKMERDKETKEDLKTVALGT
Sbjct: 822  LSRAKKGKPP--TKGADGKAKRNLNPEALERKITQTNAKIEKMERDKETKEDLKTVALGT 879

Query: 648  SKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPSFRF 511
            SKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF W+MDVDPSFRF
Sbjct: 880  SKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWSMDVDPSFRF 925


>dbj|BAK32961.1| topoisomerase I [Ophiorrhiza ridleyana]
          Length = 926

 Score = 1146 bits (2964), Expect = 0.0
 Identities = 613/944 (64%), Positives = 673/944 (71%), Gaps = 34/944 (3%)
 Frame = -3

Query: 3240 MAVEACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDSR 3061
            MAVEAC T NL +DM++D+ P++FKR+N  SKQ+Q N+E +K+S QK  GQS     D R
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPTSKQNQANAEKKKLSLQKHVGQSAVHTSDVR 60

Query: 3060 PANGESSSGQKGRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXP 2881
            PANGESSS QKGR+                                              
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPG-------------- 106

Query: 2880 ANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSASS 2701
            ANSK S S +   K  N HKS+    E K  P   A+   ++SE SDD KPL  R S  S
Sbjct: 107  ANSKLSASATSTAKQQNHHKSSAAFIEPK--PSVPAAKANSNSESSDDEKPLIARTSGCS 164

Query: 2700 SKGNTNQVSKEGSKP---------ENEDSDDEKPLSSRFPLKSGVGESTSNAYDSDDDKP 2548
            S G +N  +KEG            E+EDS+DEKPLS RFP KS +GESTS +YDSD+ KP
Sbjct: 165  SMGKSNHANKEGGDSCSIRRPVIEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKP 224

Query: 2547 LAKKLQHNGSAMRDGQPNKYSNMSNKRPPGEIKSSNQLSVKKPKLSSVTAPTNKKQASVK 2368
            LA K+Q NGSA  +G  NK +++SNKR PGE+KS NQ S+KKPKLSS     + KQA+VK
Sbjct: 225  LAAKVQQNGSASPEGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVK 284

Query: 2367 PEPKA-----------------------EXXXXDHLPISQRIXXXXXXXXXXXXXXXXXX 2257
            PEPKA                       +    DH PISQRI                  
Sbjct: 285  PEPKAEDDDDNIPLSQRGKKSQTAASKPKDEDDDHAPISQRIKKSPVSVSKSSAPVKKAS 344

Query: 2256 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXS-GEGKKWNKLEHNGVIFPPPYKPHGIKM 2080
                                             GEG+KW  L HNGV+FPPPYKPHG+KM
Sbjct: 345  TVVSTSLKKVNKKSKKVIRKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKM 404

Query: 2079 LYKGKPVDLTPEQEEVATMFAVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLENCDF 1900
            LYK +P+ LTPEQEEVATMFAVMLDTDYMNKPRFKENFF DWKKILGKNH IQNLE+CDF
Sbjct: 405  LYKRQPLTLTPEQEEVATMFAVMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDF 464

Query: 1899 SPIYEWHQSXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAWVDGKKEKVGNFRVEPPGLFR 1720
             PIYEWHQ                          KYMWA VDG KEKVGNFRVEPPGLFR
Sbjct: 465  GPIYEWHQQEKEKKKQMTTEEKKALKEERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFR 524

Query: 1719 GRGEHPKMGKLKKRIRPCDITINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDPIN 1540
            GRGEHPK+GKLKKRIRP DITINIGKDAPIPECP+PGERWKEVR+DNTVTWLA+WNDP+N
Sbjct: 525  GRGEHPKVGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVN 584

Query: 1539 PKEFKYVFLAASSTLKGLSDKEKYEKARLLKDYIQGIRAAYTKNFAS-KDPTKKQIAVAT 1363
             KE KYVFLAASSTLKG S KEKYEKAR+LKDYI GIRAAYTK F + KDP KKQIAVAT
Sbjct: 585  IKECKYVFLAASSTLKGQSVKEKYEKARVLKDYIHGIRAAYTKGFTNNKDPMKKQIAVAT 644

Query: 1362 YLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVEA 1183
            YLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILK DF+GKDSIRYQNEV+VE 
Sbjct: 645  YLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEP 704

Query: 1182 AVFKAIQQFRSGKEGSSDLFDLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRE 1003
            AVFKAIQQFRSGKEGS DLFD LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+E
Sbjct: 705  AVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKE 764

Query: 1002 TKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELKSDLS 823
            TKGG +AEKV VYQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EELK+DLS
Sbjct: 765  TKGGKIAEKVAVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLS 824

Query: 822  RVKKGKPPLKSKNADGKPKRNLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGTSK 643
            R KKGKPP  SK+ADG+PKRNLNPESLE+KIAQTNAKIEKMERDK+TKEDLK VAL TSK
Sbjct: 825  RAKKGKPP--SKDADGEPKRNLNPESLERKIAQTNAKIEKMERDKKTKEDLKAVALSTSK 882

Query: 642  INYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPSFRF 511
            I+YLDPRITVAWCKR EVPIEK+FNKSLLAKF WAMDVDPSFRF
Sbjct: 883  ISYLDPRITVAWCKRQEVPIEKMFNKSLLAKFAWAMDVDPSFRF 926


>dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. glabra]
          Length = 920

 Score = 1144 bits (2959), Expect = 0.0
 Identities = 615/939 (65%), Positives = 674/939 (71%), Gaps = 36/939 (3%)
 Frame = -3

Query: 3240 MAVEACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDSR 3061
            MAVEAC T NL +DM++D+ P++FKR+N ASKQ+Q NSE +K+S Q+  GQS     D R
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQRHVGQSAVHTSDVR 60

Query: 3060 PANGESSSGQKGRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXP 2881
            PANGE+SS QKGR+                                              
Sbjct: 61   PANGENSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSAG-------------- 106

Query: 2880 ANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSASS 2701
            ANSKPS S +   K  N HKS+    E K  P   A+   ++SE SDD KPLS R    S
Sbjct: 107  ANSKPSASATSTAKQQNHHKSSAAFIEPK--PSVPAAKANSNSESSDDEKPLSARTFGCS 164

Query: 2700 SKGNTNQVSKEGSKP---------ENEDSDDEKPLSSRFPLKSGVGESTSNAYDSDDDKP 2548
            SKG +N  +KEG            E+EDS+DEKPLS RF  KS +GESTS +YDSD+ KP
Sbjct: 165  SKGKSNHANKEGGDSCSIRRPVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKP 224

Query: 2547 LAKKLQHNGSAMRDGQPNKYSNMSNKRPPGEIKSSNQLSVKKPKLSS-VTAPTNK----- 2386
            LA K+Q NGSA RD   NK +++SNKRPPGE+KS NQ S+KKPKLSS +T+ +NK     
Sbjct: 225  LAAKVQPNGSASRDSPMNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVK 284

Query: 2385 -------------------KQASVKPEPKAEXXXXDHLPISQRIXXXXXXXXXXXXXXXX 2263
                               K  +   +PK E     ++PISQRI                
Sbjct: 285  PEPKAEDDDDNIPLSQRGKKSQTATSKPKDEDDD--NVPISQRIKKSPASVSKSSAPVKK 342

Query: 2262 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXS-GEGKKWNKLEHNGVIFPPPYKPHGI 2086
                                               GEG+KW  L HNGVIFPPPYKPHG+
Sbjct: 343  ASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV 402

Query: 2085 KMLYKGKPVDLTPEQEEVATMFAVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLENC 1906
            KMLYK +P+ LTPEQEEVATMFAVMLDTDYMNKPRFKENFF DWKK+LGKNH IQNLE+C
Sbjct: 403  KMLYKRQPITLTPEQEEVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDC 462

Query: 1905 DFSPIYEWHQSXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAWVDGKKEKVGNFRVEPPGL 1726
            DF PIYEWHQ                          KYMWA VDG KEKVGNFRVEPPGL
Sbjct: 463  DFGPIYEWHQQEKEKKKQMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGL 522

Query: 1725 FRGRGEHPKMGKLKKRIRPCDITINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDP 1546
            FRGRGEHPKMGKLKKRIRP DITINIGKDAPIPECP+PGERWKEVR+DNTVTWLA+WNDP
Sbjct: 523  FRGRGEHPKMGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDP 582

Query: 1545 INPKEFKYVFLAASSTLKGLSDKEKYEKARLLKDYIQGIRAAYTKNFAS-KDPTKKQIAV 1369
            IN KEFKYVFLAASSTLKG SDKEKYEKARLLKDYI GIRAAYTK+F + KDP KKQIAV
Sbjct: 583  INQKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAV 642

Query: 1368 ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEV 1189
            ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEV+V
Sbjct: 643  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQV 702

Query: 1188 EAAVFKAIQQFRSGKEGSSDLFDLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS 1009
            E AVFKAIQQFRSGKEGS DLFD LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS
Sbjct: 703  EPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS 762

Query: 1008 RETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELKSD 829
            ++T GG+VAEKVVVYQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EELK+D
Sbjct: 763  KKTNGGEVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTD 822

Query: 828  LSRVKKGKPPLKSKNADGKPKRNLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGT 649
            LSR KKGKP   SK ADGKPKRNLNPE+LE+KIAQTNAKIEKMERDKETKEDLKTVALGT
Sbjct: 823  LSRAKKGKP--LSKGADGKPKRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGT 880

Query: 648  SKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD 532
            SKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF WAM+
Sbjct: 881  SKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMN 919


>dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]
          Length = 920

 Score = 1143 bits (2957), Expect = 0.0
 Identities = 615/939 (65%), Positives = 673/939 (71%), Gaps = 36/939 (3%)
 Frame = -3

Query: 3240 MAVEACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDSR 3061
            MAVEAC T NL +DM++D+ P++FKR+N ASKQ+Q NSE +K+S QK  GQS     D R
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 3060 PANGESSSGQKGRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXP 2881
            PANGE+SS QKGR+                                              
Sbjct: 61   PANGENSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPG-------------- 106

Query: 2880 ANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSASS 2701
            ANSKPS S +   K  N HKS+    E K  P   A+   ++SE SDD KPLS R    S
Sbjct: 107  ANSKPSASATSTAKQQNHHKSSAAFIEPK--PSVPAAKANSNSESSDDEKPLSARTFGCS 164

Query: 2700 SKGNTNQVSKEGSKP---------ENEDSDDEKPLSSRFPLKSGVGESTSNAYDSDDDKP 2548
            SKG +N  +KEG            E+EDS+DEKPLS RF  KS +GESTS +YDSD+ KP
Sbjct: 165  SKGKSNHANKEGGDSCSIRRPVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKP 224

Query: 2547 LAKKLQHNGSAMRDGQPNKYSNMSNKRPPGEIKSSNQLSVKKPKLSS-VTAPTNK----- 2386
            LA K+Q NGSA RD   NK +++SNKRPPGE+KS NQ S+KKPKLSS +T+ +NK     
Sbjct: 225  LAAKVQPNGSASRDSPMNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVK 284

Query: 2385 -------------------KQASVKPEPKAEXXXXDHLPISQRIXXXXXXXXXXXXXXXX 2263
                               K  +   +PK E     ++PISQRI                
Sbjct: 285  PEPKAEDDDDNIPLSQRGKKSQTATSKPKDEDDD--NVPISQRIKKSPASVSKSSAPVKK 342

Query: 2262 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXS-GEGKKWNKLEHNGVIFPPPYKPHGI 2086
                                               GEG+KW  L HNGVIFPPPYKPHG+
Sbjct: 343  ASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV 402

Query: 2085 KMLYKGKPVDLTPEQEEVATMFAVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLENC 1906
            KMLYK +P+ LTPEQEEVATMFAVMLDTDYMNKPRFKENFF DWKK+LGKNH IQNLE+C
Sbjct: 403  KMLYKRQPITLTPEQEEVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDC 462

Query: 1905 DFSPIYEWHQSXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAWVDGKKEKVGNFRVEPPGL 1726
            DF PIYEWHQ                          KYMWA VDG KEKVGNFRVEPPGL
Sbjct: 463  DFGPIYEWHQQEKEKKKQMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGL 522

Query: 1725 FRGRGEHPKMGKLKKRIRPCDITINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDP 1546
            FRGRGEHPKMGKLKKRIRP DITINIGKDAPIPECP+PGERWKEVR+DNTVTWLA+WNDP
Sbjct: 523  FRGRGEHPKMGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDP 582

Query: 1545 INPKEFKYVFLAASSTLKGLSDKEKYEKARLLKDYIQGIRAAYTKNFAS-KDPTKKQIAV 1369
            IN KEFKYVFLAASSTLKG SDKEKYEKARLLKDYI GIRAAYTK+F + KDP KKQIAV
Sbjct: 583  INQKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAV 642

Query: 1368 ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEV 1189
            ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEV+V
Sbjct: 643  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQV 702

Query: 1188 EAAVFKAIQQFRSGKEGSSDLFDLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS 1009
            E AVFKAI QFRSGKEGS DLFD LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS
Sbjct: 703  EPAVFKAIHQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS 762

Query: 1008 RETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELKSD 829
            ++T GG+VAEKVVVYQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EELK+D
Sbjct: 763  KKTNGGEVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTD 822

Query: 828  LSRVKKGKPPLKSKNADGKPKRNLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGT 649
            LSR KKGKP   SK ADGKPKRNLNPE+LE+KIAQTNAKIEKMERDKETKEDLKTVALGT
Sbjct: 823  LSRAKKGKP--LSKGADGKPKRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGT 880

Query: 648  SKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD 532
            SKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF WAM+
Sbjct: 881  SKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMN 919


>dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]
          Length = 926

 Score = 1137 bits (2941), Expect = 0.0
 Identities = 613/946 (64%), Positives = 673/946 (71%), Gaps = 36/946 (3%)
 Frame = -3

Query: 3240 MAVEACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDSR 3061
            MAVEAC TPNL +DM++D+ P++FKR+N ASKQ+Q NSE +K+S QK  GQS     D R
Sbjct: 1    MAVEACTTPNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 3060 PANGESSSGQKGRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXP 2881
            PANGESSS QKGR+                                              
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPG-------------- 106

Query: 2880 ANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSASS 2701
            ANSK S S +   K  N HKS+    E K  P   A+   ++SE SDD KPL  R S  S
Sbjct: 107  ANSKLSASATSTAKQQNHHKSSAAFIEPK--PSVPAAKANSNSESSDDEKPLIARTSGCS 164

Query: 2700 SKGNTNQVSKEGSKP---------ENEDSDDEKPLSSRFPLKSGVGESTSNAYDSDDDKP 2548
            SKG +N  +KEG            E+EDS+DEKPLS RFP KS +GESTS +YDSD+ KP
Sbjct: 165  SKGKSNHANKEGGDSCSIRRPVIEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKP 224

Query: 2547 LAKKLQHNGSAMRDGQPNKYSNMSNKRPPGEIKSSNQLSVKKPKLSS-VTAPTN------ 2389
            LA K+Q NGSA RDG  NK +++ NKR PGE+KS NQ S+KK KLSS +T+ +N      
Sbjct: 225  LATKVQQNGSASRDGPMNKSASLLNKRAPGEVKSLNQSSLKKAKLSSPITSISNKQAAVK 284

Query: 2388 ------------------KKQASVKPEPKAEXXXXDHLPISQRIXXXXXXXXXXXXXXXX 2263
                              KK  +   +PK E     + PISQRI                
Sbjct: 285  PEPKAEDDDDNIPLSQRGKKSQTAASKPKDEDDD--NAPISQRIKKSPASVSKSSAPVKK 342

Query: 2262 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXS-GEGKKWNKLEHNGVIFPPPYKPHGI 2086
                                               GEG+KW  L HNGV+F PPYKPHG+
Sbjct: 343  ASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFLPPYKPHGV 402

Query: 2085 KMLYKGKPVDLTPEQEEVATMFAVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLENC 1906
            KMLYK +P+ LTPEQEEVATMFAVMLDTDYM KPRFKENFF DWKK+LGKNH +QNLE+C
Sbjct: 403  KMLYKXQPLTLTPEQEEVATMFAVMLDTDYMTKPRFKENFFSDWKKMLGKNHTVQNLEDC 462

Query: 1905 DFSPIYEWHQSXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAWVDGKKEKVGNFRVEPPGL 1726
            DF PIYEWHQ                          KYMWA VDG KEKVGNFRVEPPGL
Sbjct: 463  DFGPIYEWHQQEKEKRKQMTTEEKKALKEERLQQEEKYMWAIVDGVKEKVGNFRVEPPGL 522

Query: 1725 FRGRGEHPKMGKLKKRIRPCDITINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDP 1546
            FRGRGEHPKMGKLKKRIRP DITINIGKDAPIPECP+PGERWKEVR+DNTVTWLAFWNDP
Sbjct: 523  FRGRGEHPKMGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWNDP 582

Query: 1545 INPKEFKYVFLAASSTLKGLSDKEKYEKARLLKDYIQGIRAAYTKNFAS-KDPTKKQIAV 1369
            IN KE KYVFLAASSTLKG SDKEKYEKARLLKDYI GIRAAYTK+F + KDP KKQIAV
Sbjct: 583  INQKECKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAV 642

Query: 1368 ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEV 1189
            ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILK DF+GKDSIRYQNEV+V
Sbjct: 643  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQV 702

Query: 1188 EAAVFKAIQQFRSGKEGSSDLFDLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS 1009
            E AVFKAIQQFRSGKEG +DLFD LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS
Sbjct: 703  EPAVFKAIQQFRSGKEGCADLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS 762

Query: 1008 RETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELKSD 829
            +ETKGG VAEKV VYQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EELK+D
Sbjct: 763  KETKGGKVAEKVGVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTD 822

Query: 828  LSRVKKGKPPLKSKNADGKPKRNLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGT 649
            LSR KKGKPP  +K ADG+PKRNLNPESLE+KIAQTNAKIEKMERDK+TKEDLK VAL T
Sbjct: 823  LSRAKKGKPP--AKGADGEPKRNLNPESLERKIAQTNAKIEKMERDKKTKEDLKAVALST 880

Query: 648  SKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPSFRF 511
            SKI+YLDPRITVAWCKRHEVPIEKIFNKSLLAKF W+MDVDPSFRF
Sbjct: 881  SKISYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWSMDVDPSFRF 926


>dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]
          Length = 926

 Score = 1135 bits (2936), Expect = 0.0
 Identities = 611/946 (64%), Positives = 673/946 (71%), Gaps = 36/946 (3%)
 Frame = -3

Query: 3240 MAVEACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDSR 3061
            MAVEAC TPNL +DM++D+ P++FKR+N ASKQ+Q NSE +K+S QK  GQS     D R
Sbjct: 1    MAVEACTTPNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 3060 PANGESSSGQKGRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXP 2881
            PANGESSS QKGR+                                              
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPG-------------- 106

Query: 2880 ANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSASS 2701
            ANSK S S +   K  N HKS+    E K  P   A+   ++SE SDD KPL  R S  S
Sbjct: 107  ANSKLSASATSTAKQQNHHKSSAAFIEPK--PSVPAAKANSNSESSDDEKPLIARTSGCS 164

Query: 2700 SKGNTNQVSKEGSKP---------ENEDSDDEKPLSSRFPLKSGVGESTSNAYDSDDDKP 2548
            SKG +N  +KEG            E+EDS+DEKPLS RFP KS +GESTS ++DSD+ KP
Sbjct: 165  SKGKSNHANKEGGDSCSIRRPVIEESEDSEDEKPLSRRFPSKSSLGESTSKSHDSDEKKP 224

Query: 2547 LAKKLQHNGSAMRDGQPNKYSNMSNKRPPGEIKSSNQLSVKKPKLSS-VTAPTN------ 2389
            LA K+Q NGSA RDG  NK +++SNKR PGE+KS NQ S+KKPKLSS +T+ +N      
Sbjct: 225  LAAKVQQNGSASRDGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSTITSISNKQAAVK 284

Query: 2388 ------------------KKQASVKPEPKAEXXXXDHLPISQRIXXXXXXXXXXXXXXXX 2263
                              KK  +   +PK E     + PISQRI                
Sbjct: 285  PEPKAEDDDDNIPLSQRGKKSQTAASKPKDEDDD--NAPISQRIKKSPASVSKSSAPVKK 342

Query: 2262 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXS-GEGKKWNKLEHNGVIFPPPYKPHGI 2086
                                               GEG+KW  L HNGV+FPPPYKPHG+
Sbjct: 343  ASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGV 402

Query: 2085 KMLYKGKPVDLTPEQEEVATMFAVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLENC 1906
            KMLYK +P+ LTPEQEEVATMFA MLDTDYMNKPRFKENFF DWKKILGKNH IQNLE+C
Sbjct: 403  KMLYKRQPLTLTPEQEEVATMFAAMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDC 462

Query: 1905 DFSPIYEWHQSXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAWVDGKKEKVGNFRVEPPGL 1726
            DF PIYEWHQ                          KYMWA VDG KEKVGNFRVEPPGL
Sbjct: 463  DFGPIYEWHQQEKEKKKQMTTEEKKALKEERLQLEEKYMWAIVDGVKEKVGNFRVEPPGL 522

Query: 1725 FRGRGEHPKMGKLKKRIRPCDITINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDP 1546
            FRGRGEHPK+GKLKKRIRP DITINIGKDAPIPECP+PGERWKEVR+DNTVTWLA+WNDP
Sbjct: 523  FRGRGEHPKVGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDP 582

Query: 1545 INPKEFKYVFLAASSTLKGLSDKEKYEKARLLKDYIQGIRAAYTKNFAS-KDPTKKQIAV 1369
            +N KE KYVFLAASSTLKG SDKEKYEKARLLKDYI GIRAAYTK+F + KDP KKQ+AV
Sbjct: 583  VNLKECKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQVAV 642

Query: 1368 ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEV 1189
            ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILK DF+GKDSIRYQNEV+V
Sbjct: 643  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQV 702

Query: 1188 EAAVFKAIQQFRSGKEGSSDLFDLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS 1009
            E AVFKAIQQFRSGKEGS DLFD LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS
Sbjct: 703  EPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS 762

Query: 1008 RETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELKSD 829
            +ETKGG VAEKV VYQ ANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EELK+D
Sbjct: 763  KETKGGKVAEKVGVYQRANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTD 822

Query: 828  LSRVKKGKPPLKSKNADGKPKRNLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGT 649
            LSR KKGKPP  SK  DG+PKRNLNPE+LE+KIAQTNAKIEKMERDK+TKEDLK VAL T
Sbjct: 823  LSRAKKGKPP--SKGDDGEPKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALST 880

Query: 648  SKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPSFRF 511
            SKI+YLDPRITVAWCKR EVPIEK+FNKSLLAKF WAMDVDPSFRF
Sbjct: 881  SKISYLDPRITVAWCKRQEVPIEKMFNKSLLAKFAWAMDVDPSFRF 926


>dbj|BAK32956.1| topoisomerase I [Ophiorrhiza fucosa]
          Length = 926

 Score = 1132 bits (2929), Expect = 0.0
 Identities = 612/948 (64%), Positives = 671/948 (70%), Gaps = 38/948 (4%)
 Frame = -3

Query: 3240 MAVEACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDSR 3061
            MAVEAC T NL +DM++D+ P++FKR+N ASKQ+Q NSE +K+S QK  GQS     D R
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 3060 PANGESSSGQKGRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXP 2881
            PANGESSS QKGR+                                              
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPG-------------- 106

Query: 2880 ANSKPSTSGSFKVKPFNQHKSATVIKEEKSS--PLRLASAIINDSEDSDDGKPLSLRHSA 2707
            ANSK S S +   K  N HKS+    E K S  P +  S    +SE SDD KPL  R S 
Sbjct: 107  ANSKLSASATSTAKQQNHHKSSAAFIEPKPSVPPAKANS----NSESSDDEKPLIARTSG 162

Query: 2706 SSSKGNTNQVSKEGSKP---------ENEDSDDEKPLSSRFPLKSGVGESTSNAYDSDDD 2554
             SSKG +N  +KEG            E+EDS+DEKPLS RFP KS +GESTS +YDSD+ 
Sbjct: 163  CSSKGKSNHANKEGGDSCSIRRPVVEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEK 222

Query: 2553 KPLAKKLQHNGSAMRDGQPNKYSNMSNKRPPGEIKSSNQLSVKKPKLSS-VTAPTN---- 2389
            KPLA K+Q NGSA RDG  NK +++SNKR PGE+KS NQ S+KKPKLSS +T+ +N    
Sbjct: 223  KPLAAKVQQNGSASRDGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAA 282

Query: 2388 --------------------KKQASVKPEPKAEXXXXDHLPISQRIXXXXXXXXXXXXXX 2269
                                KK  +   +PK E     + PISQRI              
Sbjct: 283  VKPEPKAEDDDDNIPLSQRGKKSQTAASKPKDEDDD--NAPISQRIKKSPASVSKSSAPV 340

Query: 2268 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXS-GEGKKWNKLEHNGVIFPPPYKPH 2092
                                                 GEG+KW  L HNGV+FPPPYKPH
Sbjct: 341  KKASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPH 400

Query: 2091 GIKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLE 1912
            G+KMLYK +P+ LTPEQEEVATMFA MLDTDYMNKPRFKENFF DWKKILGKNH IQNLE
Sbjct: 401  GVKMLYKRQPLTLTPEQEEVATMFAAMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLE 460

Query: 1911 NCDFSPIYEWHQSXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAWVDGKKEKVGNFRVEPP 1732
            +CDF PIYEWHQ                          KYMWA VDG KEKVGNFRVEPP
Sbjct: 461  DCDFGPIYEWHQQEREKKKQMTTEEKKALKDERLQLEEKYMWAIVDGVKEKVGNFRVEPP 520

Query: 1731 GLFRGRGEHPKMGKLKKRIRPCDITINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWN 1552
            GLFRGRGEHPK+GKLKKRI P DITINIGKDAPIPECP+PGERWKEVR+DNTVTWLA+WN
Sbjct: 521  GLFRGRGEHPKVGKLKKRIHPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWN 580

Query: 1551 DPINPKEFKYVFLAASSTLKGLSDKEKYEKARLLKDYIQGIRAAYTKNFAS-KDPTKKQI 1375
            DP+N KE KYVFLA SSTLKG SDKEKYEKARLLKDYI GIRAAYTK+F + KDP KKQI
Sbjct: 581  DPVNLKECKYVFLAPSSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQI 640

Query: 1374 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEV 1195
            AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILK DF+GKDSIRYQNEV
Sbjct: 641  AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEV 700

Query: 1194 EVEAAVFKAIQQFRSGKEGSSDLFDLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 1015
            +VE AVFKAIQQFRSGKEGS DLFD LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM
Sbjct: 701  QVEPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 760

Query: 1014 LSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELK 835
            LS+ETKGG VAEKV VYQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EELK
Sbjct: 761  LSKETKGGKVAEKVGVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELK 820

Query: 834  SDLSRVKKGKPPLKSKNADGKPKRNLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVAL 655
            +DLSR KKGKPP  SK  DG+PKRNLNPE+LE+KIAQTNAKIEKMERDK+TKEDLK VAL
Sbjct: 821  TDLSRAKKGKPP--SKGDDGEPKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVAL 878

Query: 654  GTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPSFRF 511
             TSKI+YLDPRITVAWCKR EVPIEK+FNKSLLAKF WAMDVDPSFRF
Sbjct: 879  STSKISYLDPRITVAWCKRQEVPIEKMFNKSLLAKFAWAMDVDPSFRF 926


>dbj|BAK32959.1| topoisomerase I [Ophiorrhiza plumbea]
          Length = 920

 Score = 1124 bits (2906), Expect = 0.0
 Identities = 606/939 (64%), Positives = 667/939 (71%), Gaps = 36/939 (3%)
 Frame = -3

Query: 3240 MAVEACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDSR 3061
            MAVEAC TPNL +DM++D+ P++FKR+N ASKQ+Q NSE +K+S QK  GQS     D R
Sbjct: 1    MAVEACTTPNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 3060 PANGESSSGQKGRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXP 2881
            PANGESSS QKGR+                                              
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPG-------------- 106

Query: 2880 ANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSASS 2701
            ANSK S S +   K  N HKS+    E K  P   A+   ++SE SDD KPL  R S  S
Sbjct: 107  ANSKLSASATSTAKQQNHHKSSAAFIEPK--PSVPAAKANSNSESSDDEKPLIARTSGCS 164

Query: 2700 SKGNTNQVSKEGSKP---------ENEDSDDEKPLSSRFPLKSGVGESTSNAYDSDDDKP 2548
            SKG +N  +KEG            E+EDS+DEKPLS RFP KS +GESTS +YDSD+ KP
Sbjct: 165  SKGKSNHANKEGGDSCSIRRPVIEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKP 224

Query: 2547 LAKKLQHNGSAMRDGQPNKYSNMSNKRPPGEIKSSNQLSVKKPKLSS-VTAPTN------ 2389
            LA K+Q NGSA RDG  NK +++SNKR PGE+KS NQ S+KKPKLSS +T+ +N      
Sbjct: 225  LAAKVQPNGSASRDGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVK 284

Query: 2388 ------------------KKQASVKPEPKAEXXXXDHLPISQRIXXXXXXXXXXXXXXXX 2263
                              KK  +   +PK E     + PISQRI                
Sbjct: 285  PEPKAEDDDDNIPLSQRGKKSQTAASKPKDEDDD--NAPISQRIKKSPASVSKSSAPVKK 342

Query: 2262 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXS-GEGKKWNKLEHNGVIFPPPYKPHGI 2086
                                               GEG+KW  L HNGVIFPPPYKPHG+
Sbjct: 343  ASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV 402

Query: 2085 KMLYKGKPVDLTPEQEEVATMFAVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLENC 1906
            KMLYK +P+ LTPEQEEVATMFAVMLDTDYMNKPRFKENFF DWKK+LGKNH IQNLE+C
Sbjct: 403  KMLYKRQPITLTPEQEEVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDC 462

Query: 1905 DFSPIYEWHQSXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAWVDGKKEKVGNFRVEPPGL 1726
            DF PIYEWHQ                          KYMW  VDG KEKVGNFRVEPPGL
Sbjct: 463  DFGPIYEWHQQEKEKKKQMTTEEKKALKEERLQQEEKYMWVIVDGVKEKVGNFRVEPPGL 522

Query: 1725 FRGRGEHPKMGKLKKRIRPCDITINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDP 1546
            FRGRGEHPK+GKLKKRIRP DITINIGKDAPIPECP+PGERWKEVR+DNTVTWLA+WNDP
Sbjct: 523  FRGRGEHPKVGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDP 582

Query: 1545 INPKEFKYVFLAASSTLKGLSDKEKYEKARLLKDYIQGIRAAYTKNFAS-KDPTKKQIAV 1369
            IN KE KYVFL ASSTLKG SDKEKYEKARLLKDYI GIRAAYTK+F + KDP KKQIAV
Sbjct: 583  INQKERKYVFLGASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAV 642

Query: 1368 ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEV 1189
            ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILK DF+GKDSIRYQNEV+V
Sbjct: 643  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQV 702

Query: 1188 EAAVFKAIQQFRSGKEGSSDLFDLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS 1009
            E AVFKAIQQFRSGKEGS+DLFD LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS
Sbjct: 703  EPAVFKAIQQFRSGKEGSADLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS 762

Query: 1008 RETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELKSD 829
            +ETKGG VAEKV VYQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EELK+D
Sbjct: 763  KETKGGKVAEKVGVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTD 822

Query: 828  LSRVKKGKPPLKSKNADGKPKRNLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGT 649
            LSR KKGKPP  SK ADG+PKRNLNPE+LE+KIAQTNAKIEKME DK+TKEDLK VAL T
Sbjct: 823  LSRAKKGKPP--SKGADGEPKRNLNPEALERKIAQTNAKIEKMEGDKKTKEDLKAVALST 880

Query: 648  SKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD 532
            SKI+YL PRITVAWCKRHEVPIEK+FNKSLLAKF WAM+
Sbjct: 881  SKISYLGPRITVAWCKRHEVPIEKMFNKSLLAKFAWAMN 919


>dbj|BAK32963.1| topoisomerase I [Ophiorrhiza sp. 35]
          Length = 920

 Score = 1116 bits (2887), Expect = 0.0
 Identities = 604/941 (64%), Positives = 665/941 (70%), Gaps = 38/941 (4%)
 Frame = -3

Query: 3240 MAVEACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDSR 3061
            MAVEAC T NL +DM++D+ P++FKR+N ASKQ+Q NSE +K+S QK  GQS     D R
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 3060 PANGESSSGQKGRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXP 2881
            PANGESSS QKGR+                                              
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPG-------------- 106

Query: 2880 ANSKPSTSGSFKVKPFNQHKSATVIKEEKSS--PLRLASAIINDSEDSDDGKPLSLRHSA 2707
            ANSK S S +   K  N HKS+    E K S  P +  S    +SE SDD KPL  R S 
Sbjct: 107  ANSKLSASATSTAKQQNHHKSSAAFIEPKPSVPPAKANS----NSESSDDEKPLIARTSG 162

Query: 2706 SSSKGNTNQVSKEGSKP---------ENEDSDDEKPLSSRFPLKSGVGESTSNAYDSDDD 2554
             SSKG +N  +KEG            E+EDS+DEKPLS RFP KS +GESTS +YDSD+ 
Sbjct: 163  CSSKGKSNHANKEGGDSCSIRRPVVEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEK 222

Query: 2553 KPLAKKLQHNGSAMRDGQPNKYSNMSNKRPPGEIKSSNQLSVKKPKLSS-VTAPTN---- 2389
            KPLA K+Q NGSA RDG  NK +++SNKR PGE+KS NQ S+KKPKLSS +T+ +N    
Sbjct: 223  KPLAAKVQQNGSASRDGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAA 282

Query: 2388 --------------------KKQASVKPEPKAEXXXXDHLPISQRIXXXXXXXXXXXXXX 2269
                                KK  +   +PK E     + PISQRI              
Sbjct: 283  VKPEPKAEDDDDNIPLSQRGKKSQTAASKPKDEDDD--NAPISQRIKKSPASVSKSSAPV 340

Query: 2268 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXS-GEGKKWNKLEHNGVIFPPPYKPH 2092
                                                 GEG+KW  L HNGVIFPPPYKPH
Sbjct: 341  KKASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPH 400

Query: 2091 GIKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLE 1912
            G+KMLYK +P+ LTPEQEEVATMFAVMLDTDYMNKPRFKENFF DWKK+LGKNH IQNLE
Sbjct: 401  GVKMLYKRQPLTLTPEQEEVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLE 460

Query: 1911 NCDFSPIYEWHQSXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAWVDGKKEKVGNFRVEPP 1732
            +CDF PIYEWHQ                          KYMWA VDG KEKVGNFRVEPP
Sbjct: 461  DCDFGPIYEWHQQEREKKKQMTTEEKKALKDERLQQEEKYMWAIVDGVKEKVGNFRVEPP 520

Query: 1731 GLFRGRGEHPKMGKLKKRIRPCDITINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWN 1552
            GLFRGRGEHPK+GKLKKRI P DITINIGKDAPIPECP+PGERWKEVR+DNTVTWLA+WN
Sbjct: 521  GLFRGRGEHPKVGKLKKRIHPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWN 580

Query: 1551 DPINPKEFKYVFLAASSTLKGLSDKEKYEKARLLKDYIQGIRAAYTKNFAS-KDPTKKQI 1375
            DP+N KE KYVFLA SSTLKG SDKEKYEKARLLKDYI GIRAAYTK+F + KDP KKQI
Sbjct: 581  DPVNLKECKYVFLAPSSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQI 640

Query: 1374 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEV 1195
            AVATYLIDKLALRAGNEKDDDEADTVGCCTL+VENVEPVPPNILK DF+GKDSIRYQNEV
Sbjct: 641  AVATYLIDKLALRAGNEKDDDEADTVGCCTLRVENVEPVPPNILKIDFIGKDSIRYQNEV 700

Query: 1194 EVEAAVFKAIQQFRSGKEGSSDLFDLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 1015
            +VE AVFKAIQQFRSGKEGS DLFD LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM
Sbjct: 701  QVEPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 760

Query: 1014 LSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELK 835
            LS+ETKGG VAEKV VYQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EELK
Sbjct: 761  LSKETKGGKVAEKVGVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELK 820

Query: 834  SDLSRVKKGKPPLKSKNADGKPKRNLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVAL 655
            +DLSR KKGKPP  SK  DG+PKRNLNPE+LE+KIAQTNAKIEKMERDK+TKEDLK VAL
Sbjct: 821  TDLSRAKKGKPP--SKGDDGEPKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVAL 878

Query: 654  GTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD 532
             TSKI+YLDPRITVAWCKR EVPIEK+FNKSLLAKF WAM+
Sbjct: 879  STSKISYLDPRITVAWCKRQEVPIEKMFNKSLLAKFAWAMN 919


>dbj|BAK32957.1| topoisomerase I [Ophiorrhiza harrisiana]
          Length = 920

 Score = 1104 bits (2856), Expect = 0.0
 Identities = 600/941 (63%), Positives = 662/941 (70%), Gaps = 38/941 (4%)
 Frame = -3

Query: 3240 MAVEACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDSR 3061
            MAVEAC T NL +DM++D+ P++FKR+N ASKQ+Q NSE +K+S QK  GQS     D R
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 3060 PANGESSSGQKGRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXP 2881
            PANGESSS QKGR+                                              
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPG-------------- 106

Query: 2880 ANSKPSTSGSFKVKPFNQHKSATVIKEEKSS--PLRLASAIINDSEDSDDGKPLSLRHSA 2707
            ANSK S S +   K  N HKS+    E K S  P +  S    +SE SDD KPL  R S 
Sbjct: 107  ANSKLSASATSTAKQQNHHKSSAAFIEPKPSVPPAKANS----NSESSDDEKPLIARTSG 162

Query: 2706 SSSKGNTNQVSKEGSKP---------ENEDSDDEKPLSSRFPLKSGVGESTSNAYDSDDD 2554
             SSKG +N  +KEG            E+EDS+DEKPLS RFP KS +GESTS +YDSD+ 
Sbjct: 163  CSSKGKSNHANKEGGDSCSIRRPVVEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEK 222

Query: 2553 KPLAKKLQHNGSAMRDGQPNKYSNMSNKRPPGEIKSSNQLSVKKPKLSS-VTAPTN---- 2389
            KPLA K+Q NGSA RDG  NK +++SNKR PGE+KS NQ S+KKPKLSS +T+ +N    
Sbjct: 223  KPLAAKVQQNGSASRDGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAA 282

Query: 2388 --------------------KKQASVKPEPKAEXXXXDHLPISQRIXXXXXXXXXXXXXX 2269
                                KK  +   +PK E     + PISQRI              
Sbjct: 283  VKPEPKAEDDDDNIPLSQRGKKSQTAASKPKDEDDD--NAPISQRIKKSPASVSKSSAPV 340

Query: 2268 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXS-GEGKKWNKLEHNGVIFPPPYKPH 2092
                                                 GEG+KW  L HNGV+F PPYKPH
Sbjct: 341  KKASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFLPPYKPH 400

Query: 2091 GIKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLE 1912
            G+KMLYK +P+ LTPEQEEVATMFAVMLDTDYM KPRFKENFF DWKK+LGKNH +QNLE
Sbjct: 401  GVKMLYKQQPLTLTPEQEEVATMFAVMLDTDYMTKPRFKENFFSDWKKMLGKNHTVQNLE 460

Query: 1911 NCDFSPIYEWHQSXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAWVDGKKEKVGNFRVEPP 1732
            +CDF PIYEWHQ                          KYM A VDG KEKVGNFRVEPP
Sbjct: 461  DCDFGPIYEWHQQEKEKRKQMTTEEKKALKEERLQQEEKYMRAIVDGVKEKVGNFRVEPP 520

Query: 1731 GLFRGRGEHPKMGKLKKRIRPCDITINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWN 1552
            GLFRGRGEHPK+GKLKKRI P DITINIGKDAPIPECP+PGERWKEVR+DNTVTWLA+WN
Sbjct: 521  GLFRGRGEHPKVGKLKKRIHPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWN 580

Query: 1551 DPINPKEFKYVFLAASSTLKGLSDKEKYEKARLLKDYIQGIRAAYTKNFAS-KDPTKKQI 1375
            DP+N KE KYVFLA SSTLKG SDKEKYEKARLLKDYI GIRAAYTK+F + KDP KKQI
Sbjct: 581  DPVNLKECKYVFLAPSSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQI 640

Query: 1374 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEV 1195
            AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILK DF+GKDSIRYQNEV
Sbjct: 641  AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEV 700

Query: 1194 EVEAAVFKAIQQFRSGKEGSSDLFDLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 1015
            +VE AVFKAIQQFRSGKEGS DLFD LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM
Sbjct: 701  QVEPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 760

Query: 1014 LSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELK 835
            LS+ETKGG VAEKV VYQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EELK
Sbjct: 761  LSKETKGGKVAEKVGVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELK 820

Query: 834  SDLSRVKKGKPPLKSKNADGKPKRNLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVAL 655
            +DLSR KKGKPP  SK  DG+PKRNLNPE+LE+KIAQTNAKIEKMERDK+TKEDLK VAL
Sbjct: 821  TDLSRAKKGKPP--SKGDDGEPKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVAL 878

Query: 654  GTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD 532
             TSKI+YLDPRITVAWCKR EVPIEK+FNKSLLAKF WAM+
Sbjct: 879  STSKISYLDPRITVAWCKRQEVPIEKMFNKSLLAKFAWAMN 919


>dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]
          Length = 894

 Score = 1103 bits (2853), Expect = 0.0
 Identities = 588/925 (63%), Positives = 661/925 (71%), Gaps = 15/925 (1%)
 Frame = -3

Query: 3240 MAVEACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDSR 3061
            MAV+AC    + D++DEDDEP+VFKR+N+ SK +Q NS+T+K SSQ+ DGQS RQ+ D  
Sbjct: 1    MAVQACVKEKMMDEIDEDDEPLVFKRSNATSKHNQLNSDTKK-SSQRYDGQSGRQVSDVP 59

Query: 3060 PANGESSSGQKGRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXP 2881
              NG+SSS  KG+                                               
Sbjct: 60   STNGQSSSASKGKTTKLSSMKSPIASPKASTSFAKASPV--------------------- 98

Query: 2880 ANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSASS 2701
            AN K S+S   + K  ++  +  V+KEEK     L +       DS+D KPLS R     
Sbjct: 99   ANPKVSSSSDDRSKHSSKQNTINVVKEEKE----LVNPAAEPYGDSEDEKPLSARLFTGL 154

Query: 2700 SKGNTNQVSK----------EGSKPE----NEDSDDEKPLSSRFPLKSGVGESTSNAYDS 2563
            +KG++N  +K             KPE    ++DSDDE PLSS+F LK+  G ST  +Y+S
Sbjct: 155  TKGSSNNANKGLINSSPASLPVPKPEINRYSDDSDDEIPLSSKFRLKANAGTSTVKSYES 214

Query: 2562 DDDKPLAKKLQHNGSAMRDGQPNKYSNMSNKRPPGEIKSSNQLSVKKPKLSSVTAPTNKK 2383
            DD+K L    Q NGS  R    +K S   NKRP GE+KSS Q SVKKPKLS  + P N K
Sbjct: 215  DDNKTLVSNFQQNGSINRG---SKSSIKVNKRPLGEVKSSVQSSVKKPKLSDASTPVNNK 271

Query: 2382 QASVKPEPKAEXXXXDHLPISQRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2203
            QAS K EPKA+    DH+PISQR+                                    
Sbjct: 272  QASKKAEPKADDSDDDHVPISQRMKKSATSGNKSSTAKQKVTKVVSSSMKKASKKFKKVV 331

Query: 2202 XXXXXXXXXXXXXS-GEGKKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVAT 2026
                         S GEGKKWN L HNGVIFPPPYKPHG+KMLYKGKPVDLTPEQEEVAT
Sbjct: 332  KKSKYSKSSKVPPSSGEGKKWNTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVAT 391

Query: 2025 MFAVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSXXXXXXXXX 1846
            MFAVMLDTDYM K +FKENF  DW+KILGKNHVIQNLE+CDF+PIYEWHQ          
Sbjct: 392  MFAVMLDTDYMTKSKFKENFMDDWRKILGKNHVIQNLEDCDFTPIYEWHQREKEKKKKMT 451

Query: 1845 XXXXXXXXXXXXXXXXKYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPC 1666
                            KYMWA V+G KEKVGNFRVEPP LFRGRGEHPKMGKLKK IRP 
Sbjct: 452  AEEKKVLKEERLKQEEKYMWAIVNGVKEKVGNFRVEPPSLFRGRGEHPKMGKLKKCIRPS 511

Query: 1665 DITINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGL 1486
            DITINIGKDAPIPECP+PGE WKE+RHDNTVTWLAFWNDPI P+EFKYVFLAASS+LKG 
Sbjct: 512  DITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAFWNDPIKPREFKYVFLAASSSLKGQ 571

Query: 1485 SDKEKYEKARLLKDYIQGIRAAYTKNFASKDPTKKQIAVATYLIDKLALRAGNEKDDDEA 1306
            SDKEKYEKARLLKD+IQGIRAAYTK+FASKD TK+QIAVATYLIDKLALRAGNEKDDDEA
Sbjct: 572  SDKEKYEKARLLKDFIQGIRAAYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEA 631

Query: 1305 DTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSSDL 1126
            DTVGCCTLKVENVEP PP+ILKFDFLGKDSIRYQNEVEVE  V+KAIQQFR+GK G  DL
Sbjct: 632  DTVGCCTLKVENVEPKPPSILKFDFLGKDSIRYQNEVEVELPVYKAIQQFRTGKRGGDDL 691

Query: 1125 FDLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKE 946
            FD LDTSKLNAHLK LMPGLTAKVFRTYNASITLD+MLSRETKGG+VAEK+VVYQHANKE
Sbjct: 692  FDKLDTSKLNAHLKGLMPGLTAKVFRTYNASITLDEMLSRETKGGNVAEKIVVYQHANKE 751

Query: 945  VAIICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPK 766
            VAIICNHQRTVSKSH AQM RLN KI+ELK +++ L++DL+R KKGKPPL  ++ADGKPK
Sbjct: 752  VAIICNHQRTVSKSHPAQMTRLNGKIDELKGILDGLQTDLARAKKGKPPL--EDADGKPK 809

Query: 765  RNLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVP 586
            RNL PE+LE+KI QTNAKIEKMERDKETKE LKT+ALGTSKI+YLDPRITVAWCKRHEVP
Sbjct: 810  RNLTPEALERKIGQTNAKIEKMERDKETKEGLKTIALGTSKISYLDPRITVAWCKRHEVP 869

Query: 585  IEKIFNKSLLAKFTWAMDVDPSFRF 511
            IEK+FNKSLLAKF W+MDVDPSFRF
Sbjct: 870  IEKVFNKSLLAKFAWSMDVDPSFRF 894


>gb|EOY12189.1| DNA topoisomerase I alpha isoform 1 [Theobroma cacao]
            gi|508720293|gb|EOY12190.1| DNA topoisomerase I alpha
            isoform 1 [Theobroma cacao]
          Length = 904

 Score = 1018 bits (2632), Expect = 0.0
 Identities = 554/925 (59%), Positives = 635/925 (68%), Gaps = 15/925 (1%)
 Frame = -3

Query: 3240 MAVEACPTPNLRD-DMDEDDEPIVFKRNN-SASKQSQTNSETRKVSSQKRDGQSVRQIYD 3067
            MAVEA P  ++ D D D+DD P+VFKRNN S+SKQ+Q NSE +K SSQ+ DGQS RQ+ D
Sbjct: 1    MAVEA-PAKHVYDFDDDDDDGPVVFKRNNTSSSKQNQLNSEVKKASSQRSDGQSGRQVSD 59

Query: 3066 SRPANGESSSGQKGRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2887
             R  NG+SS+  K +                                             
Sbjct: 60   VRSPNGQSSNAPKNKSISSSKSPPVKSPILSPKASTSSTKALPVKSPV------------ 107

Query: 2886 XPANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSA 2707
               N K STS + + K   +    T +KE +S P++  +   +D +D DD  PLS R   
Sbjct: 108  --VNFKASTSLNDQSKQALKQNMTTAVKEGRS-PIKGTTEPNSDDDDDDDSLPLSARLKG 164

Query: 2706 SSSKGNTNQ-----------VSKEGSKPENEDSDDEKPLSSRFPLKSGVGESTSNAYDSD 2560
             S++GN              V K   K   ED DDE PLS+RF +KS  G S+S  +D D
Sbjct: 165  ISNQGNKGASTSAPAQSRRLVPKTEVKVSAEDPDDEAPLSARFNVKSNTGTSSSRLHDCD 224

Query: 2559 DDKPLAKKLQHNGSAMRDGQPNKYSNMSNKRPPGEIKSSNQLSVKKPKLSSVTAPTNKKQ 2380
            + KPLA K+Q NGS M+  Q N  S +S KRP  +  SS+  S KKPK S        KQ
Sbjct: 225  EKKPLASKIQQNGSIMKGKQQNS-STLSGKRPLDKGNSSDHSSAKKPKTSDAPTTMKTKQ 283

Query: 2379 ASVKPEPKAEXXXXDHLPISQRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2200
             +VK E   E     H+PI+QR+                                     
Sbjct: 284  VTVKAEKADEDDD--HMPIAQRMKKSTASNSKLSSMKQKTTKVVSSSFKKINKKSKKEMK 341

Query: 2199 XXXXXXXXXXXXS-GEG-KKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVAT 2026
                        S G+G KKW+ L HNGVIFP PY PHG+KMLY G+PVDLTPEQEEVAT
Sbjct: 342  SSKYIKSTKVPPSSGDGQKKWSTLVHNGVIFPSPYTPHGVKMLYDGRPVDLTPEQEEVAT 401

Query: 2025 MFAVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSXXXXXXXXX 1846
            MFAVM DTDYM+K +FK+NF+ DW K+LGKNH I++L+ CDF+PIYEWH           
Sbjct: 402  MFAVMKDTDYMSKTQFKKNFWEDWSKLLGKNHTIKDLDRCDFTPIYEWHLQEKEKKKQMS 461

Query: 1845 XXXXXXXXXXXXXXXXKYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPC 1666
                            K+MWA VDG KEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRP 
Sbjct: 462  SEEKKALKEEKLKQEEKFMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPS 521

Query: 1665 DITINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGL 1486
            DITINIGKDAPIPECP+PGERWK+++HDNTVTWLAFWNDPINPKEFKYVFLAASS+LKG 
Sbjct: 522  DITINIGKDAPIPECPIPGERWKDIKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQ 581

Query: 1485 SDKEKYEKARLLKDYIQGIRAAYTKNFASKDPTKKQIAVATYLIDKLALRAGNEKDDDEA 1306
            SDKEKYEKAR+LKDYI+ IRAAYTK+F +KD  K+QIAVATYLIDKLALRAGNEKDDDEA
Sbjct: 582  SDKEKYEKARMLKDYIKNIRAAYTKDFTTKDVMKRQIAVATYLIDKLALRAGNEKDDDEA 641

Query: 1305 DTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSSDL 1126
            DTVGCCTLKV NVE +PPN LKFDFLGKDSI+Y N VEVE  V+KAI QF++GK  S DL
Sbjct: 642  DTVGCCTLKVGNVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKSKSDDL 701

Query: 1125 FDLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKE 946
            FD LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+ML++ETK GDVAEKVVVYQ ANKE
Sbjct: 702  FDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLNKETKDGDVAEKVVVYQRANKE 761

Query: 945  VAIICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPK 766
            VAIICNHQR++SKSHSAQM RL EKI ELK V++ELK DL R KKGKPPL  K+ADGK K
Sbjct: 762  VAIICNHQRSISKSHSAQMSRLTEKITELKGVLKELKIDLDRAKKGKPPL--KDADGKQK 819

Query: 765  RNLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVP 586
            RNL P++++KKI QTNAKIEKMERD +TKEDLKTVALGTSKINYLDPRITVAWCKRHEVP
Sbjct: 820  RNLTPQAIQKKIDQTNAKIEKMERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVP 879

Query: 585  IEKIFNKSLLAKFTWAMDVDPSFRF 511
            IEKIFNKSLLAKF WAMDVDP FRF
Sbjct: 880  IEKIFNKSLLAKFAWAMDVDPDFRF 904


>ref|XP_006364175.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 1-like [Solanum
            tuberosum]
          Length = 905

 Score = 1003 bits (2593), Expect = 0.0
 Identities = 542/926 (58%), Positives = 628/926 (67%), Gaps = 16/926 (1%)
 Frame = -3

Query: 3240 MAVEACPTPNLRDDMDEDDE-PIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDS 3064
            MAVEA    NL +D+D+DD+ P+VFKR+++ SKQ+Q+NS     SSQK+DG+S RQ+ D 
Sbjct: 1    MAVEAFAKTNLMEDIDDDDDMPLVFKRSSTTSKQNQSNS-----SSQKQDGRSGRQVPDV 55

Query: 3063 RPANGESSSGQK------GRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2902
            R  NG+SSS  K       +                                        
Sbjct: 56   RSPNGQSSSTHKVKTAASSKASPAVSPLTSPKAAPLSSRTSPAPNFRTSPAPNSRTPPAP 115

Query: 2901 XXXXXXPANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLS 2722
                    NS+PS+S   + K  NQ  +  +  +E    +   S   +++EDS+D KPLS
Sbjct: 116  NSRTSPAPNSRPSSSAGNQAKNVNQQSN--IAPKESKQAIEPKSEPNDEAEDSEDDKPLS 173

Query: 2721 LRHSASSSKGN---------TNQVSKEGSKPENEDSDDEKPLSSRFPLKSGVGESTSNAY 2569
             R  +  SK N         T+   ++   P+ EDSDDE PL+SRF +KS  G STS   
Sbjct: 174  ARVPSGLSKSNSIHANNVLGTSTSVQKSRPPKKEDSDDEIPLASRFQMKSSAGASTSKFS 233

Query: 2568 DSDDDKPLAKKLQHNGSAMRDGQPNKYSNMSNKRPPGEIKSSNQLSVKKPKLSSVTAPTN 2389
             S++ KP   K++ NG           + + +KRPPGE+    +L +K            
Sbjct: 234  SSEEVKP---KIRQNGLPS--------ATVLSKRPPGEVSLLLRLQLKSLDFLMHLHLFL 282

Query: 2388 KKQASVKPEPKAEXXXXDHLPISQRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2209
                SVK E K E      +P+SQRI                                  
Sbjct: 283  VSNXSVKTEKKTEDDDD-EVPLSQRIKKAVASASASASKVSSVKKATKVVSSSMKKTKKK 341

Query: 2208 XXXXXXXXXXXXXXXSGEGKKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVA 2029
                           SG+G+KW  LEHNGVIFPPPYKPHG+KMLYKGKPVDLTPEQEEVA
Sbjct: 342  LKKPKYSKSSKLQPSSGDGQKWTTLEHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVA 401

Query: 2028 TMFAVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSXXXXXXXX 1849
            TM+AVMLDT+Y+ K +FKENF  DW+KILGKNHVIQ LE C+F+PIYEWHQS        
Sbjct: 402  TMYAVMLDTEYLTKQQFKENFMNDWRKILGKNHVIQKLEECNFTPIYEWHQSEKEKKKQM 461

Query: 1848 XXXXXXXXXXXXXXXXXKYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRP 1669
                             KYMWA VDG KEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRP
Sbjct: 462  SSEEKKALREEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRP 521

Query: 1668 CDITINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKG 1489
             DITINIGK  P+PECP+PG+RWKEVRHDNTVTWLAFWNDPINP+EFKYVFLAASS+LKG
Sbjct: 522  NDITINIGKGVPVPECPIPGQRWKEVRHDNTVTWLAFWNDPINPREFKYVFLAASSSLKG 581

Query: 1488 LSDKEKYEKARLLKDYIQGIRAAYTKNFASKDPTKKQIAVATYLIDKLALRAGNEKDDDE 1309
             SDKEKYEKAR LKDYI+GIR+AYTK+F SKDP K+QIAVATYLIDKLALRAGNEKDDDE
Sbjct: 582  QSDKEKYEKARRLKDYIEGIRSAYTKDFTSKDPVKRQIAVATYLIDKLALRAGNEKDDDE 641

Query: 1308 ADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSSD 1129
            ADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEV V   VFKAIQQFRSGK+G  D
Sbjct: 642  ADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVAVYEPVFKAIQQFRSGKKGGDD 701

Query: 1128 LFDLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANK 949
            LFD LDTSKLNAHLKELMPGLTAKVFRTYNAS TL+  L++ T+GG++A+KV VY  ANK
Sbjct: 702  LFDKLDTSKLNAHLKELMPGLTAKVFRTYNASFTLEQQLTKLTQGGELADKVAVYNVANK 761

Query: 948  EVAIICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKP 769
            EVAIICNHQRTVSKSHS Q+ RLNEKI+ELKA++EE K DL+R KKGKPP+  K ADGK 
Sbjct: 762  EVAIICNHQRTVSKSHSVQISRLNEKIDELKAILEEFKVDLARAKKGKPPV--KGADGKA 819

Query: 768  KRNLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV 589
            KRNL PE+L+KKI QTN KI+ +ER  ETKE+LKTVALGTSKINYLDPRITVAWCKRHEV
Sbjct: 820  KRNLTPEALQKKIDQTNVKIDNIERQIETKEELKTVALGTSKINYLDPRITVAWCKRHEV 879

Query: 588  PIEKIFNKSLLAKFTWAMDVDPSFRF 511
            PIEK+FNKSLLAKF WAMDV+PSF F
Sbjct: 880  PIEKMFNKSLLAKFAWAMDVEPSFTF 905


>ref|XP_006474977.1| PREDICTED: DNA topoisomerase 1-like isoform X1 [Citrus sinensis]
            gi|568842074|ref|XP_006474978.1| PREDICTED: DNA
            topoisomerase 1-like isoform X2 [Citrus sinensis]
            gi|568842076|ref|XP_006474979.1| PREDICTED: DNA
            topoisomerase 1-like isoform X3 [Citrus sinensis]
            gi|568842078|ref|XP_006474980.1| PREDICTED: DNA
            topoisomerase 1-like isoform X4 [Citrus sinensis]
          Length = 902

 Score =  993 bits (2566), Expect = 0.0
 Identities = 543/923 (58%), Positives = 627/923 (67%), Gaps = 13/923 (1%)
 Frame = -3

Query: 3240 MAVEACPTPNLRDDMDEDDE-PIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDS 3064
            MAVEA   P+   D D+D++ P VFKRN +AS+Q+  N E ++ SS   +GQ+      +
Sbjct: 1    MAVEASSKPSRVYDFDDDEDGPAVFKRNTAASRQNLANPEVKRPSSSTANGQN-----SN 55

Query: 3063 RPANGESSSGQKGRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2884
             P +  + S  K                                                
Sbjct: 56   APKDKTTVSSSK------VLPVKSPPPSQKATTSSAKASPSKSPMRSPVKSPVRSPVKSP 109

Query: 2883 PANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSAS 2704
             ANSK S+    ++K   QH +  V+K+E+   ++  + + +D  DS+D KPLS R   +
Sbjct: 110  VANSKESSPLDDRLKQSPQHNALAVVKKEE---IKDGNGLKSDDNDSEDDKPLSARLKGN 166

Query: 2703 SSKGNTNQ----------VSKEGSKPENEDSDDEKPLSSRFPLKSGVGESTSNAYDSDDD 2554
            S   N NQ          +S+   K + EDSDDE PLSSRFP KS  G S +   DSD+ 
Sbjct: 167  SK--NVNQGIGASKADAAISEVNVKTDPEDSDDEVPLSSRFP-KSNAGTSGAKPIDSDEK 223

Query: 2553 KPLAKKLQHNGSAMRDGQPNKYSNMSNKRPPGEIKSSNQLSVKKPKLSSVTAPTNKKQAS 2374
            KPLA K+Q NGS  R+ Q  K S++  KRP  +  SS   S KKPK+S  +     KQ +
Sbjct: 224  KPLASKVQQNGSTSRETQ-QKSSSVPVKRPLQKASSSGASSAKKPKVSDTSKEVKVKQVT 282

Query: 2373 VKPEPKAEXXXXDHLPISQRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2194
            VK E KA+     H+PISQR+                                       
Sbjct: 283  VKVEKKADDDD--HIPISQRMKNSAPSVKKSVTNTAKATKSVSSSSNKINKKTKKVIKNS 340

Query: 2193 XXXXXXXXXXS-GEG-KKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVATMF 2020
                        G+G KKW  L HNGVIFPPPY PHG+KMLYKGK V+LTPEQEEVATMF
Sbjct: 341  QYSKSTKMLPGSGDGQKKWTTLVHNGVIFPPPYLPHGVKMLYKGKEVNLTPEQEEVATMF 400

Query: 2019 AVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSXXXXXXXXXXX 1840
            AVMLDTDYM KP+F+ENF+ DW+K+LGKNHVIQNLE CDF PIY+WHQ            
Sbjct: 401  AVMLDTDYMQKPKFRENFWNDWRKLLGKNHVIQNLEGCDFKPIYDWHQEQKEKKKQMSSE 460

Query: 1839 XXXXXXXXXXXXXXKYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCDI 1660
                          KYMWA VDG KEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI+P DI
Sbjct: 461  EKKALKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDI 520

Query: 1659 TINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGLSD 1480
            TINIGKD PIPECP+PGE WKEV+HDNTVTWLAFWNDPINPKEFKYVFLAASS+LKG SD
Sbjct: 521  TINIGKDVPIPECPIPGESWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSD 580

Query: 1479 KEKYEKARLLKDYIQGIRAAYTKNFASKDPTKKQIAVATYLIDKLALRAGNEKDDDEADT 1300
            KEKYEKAR LKDYI  IRAAYTK+F S+D T++QIAVATYLIDKLALRAGNEKDDDEADT
Sbjct: 581  KEKYEKARKLKDYIHSIRAAYTKDFVSRDGTRRQIAVATYLIDKLALRAGNEKDDDEADT 640

Query: 1299 VGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSSDLFD 1120
            VGCCTLKV NVE +PPN LKFDFLGKDSI+Y N VEVE  V+KAI QF++GK+ + DLFD
Sbjct: 641  VGCCTLKVGNVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFD 700

Query: 1119 LLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKEVA 940
             LDT+KLNAHLKELMPGLTAKVFRTYNASITLD ML++ T  GDVA K+ VYQ ANKEVA
Sbjct: 701  KLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTGDGDVAVKIDVYQRANKEVA 760

Query: 939  IICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPKRN 760
            IICNHQRTVSK+HSAQM RL EKIE+LK V+++L+ DL R KKGKPPL  K++DGK KRN
Sbjct: 761  IICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPL-MKDSDGKRKRN 819

Query: 759  LNPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIE 580
            L PE+LE+K+AQTNAKIEKMERD +TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIE
Sbjct: 820  LAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIE 879

Query: 579  KIFNKSLLAKFTWAMDVDPSFRF 511
            KIFNKSLLAKF WAMDVDP FRF
Sbjct: 880  KIFNKSLLAKFAWAMDVDPEFRF 902


>ref|XP_006452479.1| hypothetical protein CICLE_v10007398mg [Citrus clementina]
            gi|567920950|ref|XP_006452481.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
            gi|557555705|gb|ESR65719.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
            gi|557555707|gb|ESR65721.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
          Length = 902

 Score =  991 bits (2562), Expect = 0.0
 Identities = 541/923 (58%), Positives = 627/923 (67%), Gaps = 13/923 (1%)
 Frame = -3

Query: 3240 MAVEACPTPNLRDDMDEDDE-PIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDS 3064
            MAVEA   P+   D D+D++ P VFKRN +AS+Q+  N E ++ SS   +GQ+      +
Sbjct: 1    MAVEASSKPSRVYDFDDDEDGPAVFKRNTAASRQNLANPEVKRPSSSTANGQN-----SN 55

Query: 3063 RPANGESSSGQKGRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2884
             P +  + S  K                                                
Sbjct: 56   APKDKTTVSSSK------VLPVKSPPPSQKATTSSAKASPLKSPMRSPVKSPVRSPVKSP 109

Query: 2883 PANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSAS 2704
             ANSK S+    ++K   QH +  V+K+E+   ++  + + +D  DS+D KPLS R   +
Sbjct: 110  VANSKESSPLDDRLKQLPQHNALAVVKKEE---IKDGNGLKSDDNDSEDDKPLSARLKGN 166

Query: 2703 SSKGNTNQ----------VSKEGSKPENEDSDDEKPLSSRFPLKSGVGESTSNAYDSDDD 2554
            +   N NQ          +S+   K + EDSDDE PLSSRFP KS  G S +   DSD+ 
Sbjct: 167  TK--NVNQGIGASKADAAISEVNVKTDPEDSDDEVPLSSRFP-KSNAGTSGAKPIDSDEK 223

Query: 2553 KPLAKKLQHNGSAMRDGQPNKYSNMSNKRPPGEIKSSNQLSVKKPKLSSVTAPTNKKQAS 2374
            KPLA K+Q NGS  R+ Q  K S++  KRP  +  SS   S KKPK+S  +     KQ +
Sbjct: 224  KPLASKVQQNGSTSRETQ-QKSSSVPVKRPLQKASSSGASSAKKPKVSDTSKEVKVKQVT 282

Query: 2373 VKPEPKAEXXXXDHLPISQRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2194
            VK E KA+     H+PISQR+                                       
Sbjct: 283  VKVEKKADDDD--HIPISQRMKNSAPSVKKSVTNTAKATKSVSSSSKKINKKTKKVIKNS 340

Query: 2193 XXXXXXXXXXS-GEG-KKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVATMF 2020
                        G+G KKW  L HNGVIFPPPY PHG+KMLYKGK V+LTPEQEEVATMF
Sbjct: 341  QYSKSTKMLPGSGDGQKKWTTLVHNGVIFPPPYLPHGVKMLYKGKEVNLTPEQEEVATMF 400

Query: 2019 AVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSXXXXXXXXXXX 1840
            AVMLDTDYM KP+F+ENF+ DW+K+LGKNHVIQNLE CDF PIY+WHQ            
Sbjct: 401  AVMLDTDYMQKPKFRENFWNDWRKLLGKNHVIQNLEGCDFKPIYDWHQEQKEKKKQMSSE 460

Query: 1839 XXXXXXXXXXXXXXKYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCDI 1660
                          KYMWA VDG KEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI+P DI
Sbjct: 461  EKKALKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDI 520

Query: 1659 TINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGLSD 1480
            TINIGKD PIPECP+PGE WKEV+HDNTVTWLAFWNDPINPKEFKYVFLAASS+LKG SD
Sbjct: 521  TINIGKDVPIPECPIPGESWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSD 580

Query: 1479 KEKYEKARLLKDYIQGIRAAYTKNFASKDPTKKQIAVATYLIDKLALRAGNEKDDDEADT 1300
            +EKYEKAR LKDYI  IRAAYTK+F S+D T++QIAVATYLIDKLALRAGNEKDDDEADT
Sbjct: 581  REKYEKARKLKDYIHSIRAAYTKDFVSRDGTRRQIAVATYLIDKLALRAGNEKDDDEADT 640

Query: 1299 VGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSSDLFD 1120
            VGCCTLKV NVE +PPN LKFDFLGKDSI+Y N VEVE  V+KAI QF++GK+ + DLFD
Sbjct: 641  VGCCTLKVGNVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFD 700

Query: 1119 LLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKEVA 940
             LDT+KLNAHLKELMPGLTAKVFRTYNASITLD ML++ T  GDVA K+ VYQ ANKEVA
Sbjct: 701  KLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTGDGDVAVKIDVYQRANKEVA 760

Query: 939  IICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPKRN 760
            IICNHQRTVSK+HSAQM RL EKIE+LK V+++L+ DL R KKGKPPL  K++DGK KRN
Sbjct: 761  IICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPL-MKDSDGKRKRN 819

Query: 759  LNPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIE 580
            L PE+LE+K+AQTNAKIEKMERD +TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIE
Sbjct: 820  LAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIE 879

Query: 579  KIFNKSLLAKFTWAMDVDPSFRF 511
            KIFNKSLLAKF WAMDVDP FRF
Sbjct: 880  KIFNKSLLAKFAWAMDVDPEFRF 902


>ref|XP_002300344.1| DNA topoisomerase family protein [Populus trichocarpa]
            gi|222847602|gb|EEE85149.1| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 877

 Score =  976 bits (2523), Expect = 0.0
 Identities = 534/908 (58%), Positives = 605/908 (66%), Gaps = 7/908 (0%)
 Frame = -3

Query: 3213 NLRDDMDEDDEPIVFKRN-NSASKQSQTNSETRKVSSQKRDGQSVRQIYDSRPANGESSS 3037
            N  DD D+DD PIVFKR  NS SKQ+Q N E +K SS             S+ +NG+S +
Sbjct: 13   NFNDDDDDDDGPIVFKRGGNSTSKQNQLNPEAKKPSSS------------SQNSNGQSLN 60

Query: 3036 GQKGRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPANSKPSTS 2857
             QKG+                                                 ++  TS
Sbjct: 61   LQKGKSPIPSSNASPMKSSTGSPKASASSAKASPLKSPLTY-------------TRALTS 107

Query: 2856 GSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSASSSKGNTNQV 2677
             + ++K  ++   +  +KEE  S        I D EDS+D KPLS R      KG+TN V
Sbjct: 108  SNDQLKQASKQVVSNAVKEETKS--------IVDDEDSEDDKPLSSR-----IKGSTNNV 154

Query: 2676 SKEGSKP----ENEDSDDEKPLSSRFPLKSGVGESTSNAYDSDDDKPLAKKLQHNGSAMR 2509
            +K  + P    +    DDE PLSSRF +KS  G S+S +  S + +P   K Q NGS   
Sbjct: 155  NKGVTAPAHVKDEPSDDDEVPLSSRFAMKSNAGTSSSKSIRSSEIRPFPSKSQLNGSTKN 214

Query: 2508 DGQPNKYSNMSNKRPPGEIKSSNQLSVKKPKLSSVTAPTNKKQASVKPEPKAEXXXXDHL 2329
            D Q  K S +  KRP      SN  S KKPKL      T  KQ +VK E KA+     HL
Sbjct: 215  DKQ-QKSSVVPTKRPMDNKVPSNHSSAKKPKLLDACTTTKVKQVTVKVEQKADDDD--HL 271

Query: 2328 PISQRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSGEG- 2152
             ISQR+                                                      
Sbjct: 272  TISQRMKKADSSANKSSFAKKKVTKVVSSSLKKTTQKNKKQMKNSKYSKSTKVQPGSSDG 331

Query: 2151 -KKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMNKPRFK 1975
             KKW  L HNGVIFPPPYKPHG+K+LYKGKP+DLTPEQEEVATMFAVM DTDY+ KP+F+
Sbjct: 332  QKKWTTLVHNGVIFPPPYKPHGVKILYKGKPIDLTPEQEEVATMFAVMKDTDYVQKPQFR 391

Query: 1974 ENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSXXXXXXXXXXXXXXXXXXXXXXXXXK 1795
            +NF+ DW+K+LGKNHVIQ L++CDF+PIYEWHQ                          K
Sbjct: 392  QNFWNDWRKLLGKNHVIQKLDDCDFNPIYEWHQQEKEKKKQMSTEEKKVLKEEKLKQEEK 451

Query: 1794 YMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCDITINIGKDAPIPECPV 1615
            YMWA V+G KEKVGNFRVEPPGLFRGRGEHPKMGKLK RIRP DITINIGKDAPIPECP+
Sbjct: 452  YMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKSRIRPSDITINIGKDAPIPECPI 511

Query: 1614 PGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGLSDKEKYEKARLLKDYIQ 1435
            PGERWKEV+HDNTVTWLAFWNDPINPKEFKYVFLAASS+LKG SDKEKYEKAR LKDYI 
Sbjct: 512  PGERWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIH 571

Query: 1434 GIRAAYTKNFASKDPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVP 1255
             IRAAYTK+FASKD TK+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NVE +P
Sbjct: 572  NIRAAYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVANVECIP 631

Query: 1254 PNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSSDLFDLLDTSKLNAHLKELM 1075
            PN LKFDFLGKDSIRY+N VEVE  V+KAI  F+  K+ + DLFD LDTSKLNAHLKELM
Sbjct: 632  PNKLKFDFLGKDSIRYENTVEVELPVYKAIGHFQVAKKQTDDLFDSLDTSKLNAHLKELM 691

Query: 1074 PGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSA 895
            PGLTAKVFRTYNASITLD+ L  ET+ GDVAEK+V+Y  ANK+VAIICNHQRT+SKSH A
Sbjct: 692  PGLTAKVFRTYNASITLDEKLYEETEDGDVAEKIVIYNQANKQVAIICNHQRTISKSHDA 751

Query: 894  QMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPKRNLNPESLEKKIAQTNA 715
            QM RL EKIEELK+ ++ELK+DL R KKGKPPL  K ADGK KR+L PE++EKKIA TN 
Sbjct: 752  QMSRLTEKIEELKSTLKELKTDLDRAKKGKPPL--KGADGKQKRSLTPEAIEKKIATTNQ 809

Query: 714  KIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM 535
            KIEKME   +TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPI+KIFNKSLLAKFTWAM
Sbjct: 810  KIEKMEMAMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIDKIFNKSLLAKFTWAM 869

Query: 534  DVDPSFRF 511
            DVDP FRF
Sbjct: 870  DVDPQFRF 877


>ref|XP_002529020.1| DNA topoisomerase type I, putative [Ricinus communis]
            gi|223531500|gb|EEF33331.1| DNA topoisomerase type I,
            putative [Ricinus communis]
          Length = 891

 Score =  972 bits (2513), Expect = 0.0
 Identities = 539/927 (58%), Positives = 626/927 (67%), Gaps = 17/927 (1%)
 Frame = -3

Query: 3240 MAVEACPTPNLRD-DMDEDDEPIVFKR-NNSASKQSQTNSETRKVSSQKRDGQSVRQIYD 3067
            MA  A   PN+ + D D+DD P+VFKR NNS +KQ+Q+N E +K             +  
Sbjct: 3    MAAPATAKPNIYEYDEDDDDMPLVFKRGNNSTTKQNQSNPEVKK------------PLLS 50

Query: 3066 SRPANGESSSGQKGRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2887
            S+ +NG+SS+ QKG+                                             
Sbjct: 51   SQNSNGQSSNAQKGKSTVPSLKASPVKSPIGSPKASTSSAKASPLRSPV----------- 99

Query: 2886 XPANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIIN-------DSEDSDDGKP 2728
              ANSK S+S   ++K  ++  ++ V+K+  S+   +    +        D EDS+D  P
Sbjct: 100  --ANSKGSSSLDEQLKQASKQNASNVVKDVSSAKPEIGLKSVKHETKSNGDDEDSEDDLP 157

Query: 2727 LSLRHSASSSKGNTNQVSKEGSKPE---NEDSDDEK-PLSSRFPLKSGVGESTSNAYDSD 2560
            LS R      KGNTN VSK  + P+   +EDSDD+K PL SRFP+KS  G S +   +  
Sbjct: 158  LSARR-----KGNTNNVSKVVTAPKRVKDEDSDDDKVPLCSRFPMKSTAGTSGNKPNNIS 212

Query: 2559 DDKPLAKKLQHNGSAMRDGQPNKYSNMSNKRPPGEIKSSNQLSVKKPKLSSVTAPTNKKQ 2380
            + KPL  K+Q NGS  +D Q  K   +  KRP  +  SS Q S+KKPKLS+ +  T  KQ
Sbjct: 213  EKKPLPSKVQQNGSTSKDKQ-QKAPLIPTKRPLDKANSSEQSSIKKPKLSAGSTITKVKQ 271

Query: 2379 ASVKPEPKAEXXXXDHLPISQR---IXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2209
            A+V    KAE    D +PI+QR   +                                  
Sbjct: 272  ATV----KAEEDDPDDIPIAQRKKSLGSSESKLSSAKQKAIKVVSSSFKKPIKKNKKQMK 327

Query: 2208 XXXXXXXXXXXXXXXSGEGKKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVA 2029
                            G+ K W  L HNGVIFPPPYKPHGIK+LYKG+PVDL PEQEEVA
Sbjct: 328  NTKYSKSTKVQPSSTDGQKK-WTTLIHNGVIFPPPYKPHGIKILYKGRPVDLAPEQEEVA 386

Query: 2028 TMFAVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSXXXXXXXX 1849
            TMFAVM DTDYM KP+F ENF+ DW+K+LG+NHVIQ LE+CDF+PIYEWH+         
Sbjct: 387  TMFAVMKDTDYMQKPKFLENFWNDWRKLLGRNHVIQKLEDCDFTPIYEWHEREKEKKKQM 446

Query: 1848 XXXXXXXXXXXXXXXXXKYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRP 1669
                             KYMWA VDG KEKVGNFRVEPP LFRGRGEHPKMGKLKKRI+P
Sbjct: 447  STEEKKAQKEEKLRQEEKYMWAIVDGVKEKVGNFRVEPPALFRGRGEHPKMGKLKKRIQP 506

Query: 1668 CDITINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKG 1489
             DITINIGKDAPIPECP+PGE WKEV+HDNTVTWLAFWNDPINPKEFKYVFLAASS+LKG
Sbjct: 507  SDITINIGKDAPIPECPIPGESWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKG 566

Query: 1488 LSDKEKYEKARLLKDYIQGIRAAYTKNFASKDPTKKQIAVATYLIDKLALRAGNEKDDDE 1309
             SDKEKYEKAR LKDYI  IRAAY K+  SKD TKKQIAVATYLIDKLALRAGNEKDDDE
Sbjct: 567  QSDKEKYEKARKLKDYIHNIRAAYQKDLRSKDITKKQIAVATYLIDKLALRAGNEKDDDE 626

Query: 1308 ADTVGCCTLKVENVEPVPPNI-LKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSS 1132
            ADTVGCCTLKV NVE +P +  LKFDFLGKDSIRY+N VEV+  V++AI  F+ GK+ + 
Sbjct: 627  ADTVGCCTLKVANVECIPGSFNLKFDFLGKDSIRYENTVEVKPEVYEAIGTFQKGKKQTD 686

Query: 1131 DLFDLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHAN 952
            DLFD LDT+KLNAHLKELMPGLTAKVFRTYNASITLD+ L  ET+ GDVAEKVV+YQ AN
Sbjct: 687  DLFDKLDTTKLNAHLKELMPGLTAKVFRTYNASITLDEKLYEETEDGDVAEKVVIYQRAN 746

Query: 951  KEVAIICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGK 772
            KEVAIICNHQRT+SKSH AQM +L EKIEELKA ++ELK+DL R KKGKPPL  K+ADGK
Sbjct: 747  KEVAIICNHQRTISKSHGAQMSKLIEKIEELKATLKELKTDLDRAKKGKPPL--KDADGK 804

Query: 771  PKRNLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE 592
             KRNL+PE++EKKIA TN +IEKME + +TKEDLKTVALGTSKINYLDPRITVAWCKRHE
Sbjct: 805  QKRNLSPENIEKKIASTNQRIEKMELNMKTKEDLKTVALGTSKINYLDPRITVAWCKRHE 864

Query: 591  VPIEKIFNKSLLAKFTWAMDVDPSFRF 511
            VPIEKIFNKSLLAKFTWAMDVDP FRF
Sbjct: 865  VPIEKIFNKSLLAKFTWAMDVDPQFRF 891


>ref|XP_002317355.1| DNA topoisomerase family protein [Populus trichocarpa]
            gi|222860420|gb|EEE97967.1| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 860

 Score =  964 bits (2491), Expect = 0.0
 Identities = 533/923 (57%), Positives = 606/923 (65%), Gaps = 13/923 (1%)
 Frame = -3

Query: 3240 MAVEACPTPNLRD--DMDEDDEPIVFKRN-NSASKQSQTNSETRKVSS--QKRDGQSVRQ 3076
            M V+A P P L +  D D+DD PIVFKR  NS SKQ+Q N E +K SS  Q  +GQS+  
Sbjct: 1    MVVQAPPKPILNNFNDDDDDDGPIVFKRGGNSTSKQNQPNLEAKKPSSSSQNSNGQSLNA 60

Query: 3075 IYDSRPANGESSSGQKGRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2896
                 P +  ++S  K  +                                         
Sbjct: 61   HKGKSPISSSNASPVKSPI----------------------------------------- 79

Query: 2895 XXXXPANSKPSTSGSFKVKP------FNQHKSATVIKEEKSSPLRLASAIINDSEDSDDG 2734
                   S  +++ S K  P      +++  S+++  +E++ P       I D +DS+D 
Sbjct: 80   ------GSPKASASSAKASPMKPPVTYSRVPSSSIAVKEETKP-------IVDDDDSEDD 126

Query: 2733 KPLSLRHSASSSKGNTNQVSKEGSKPENEDSDDEKPLSSRFPLKSGVGESTSNAYDSDDD 2554
            KPLS R   S++  N         K E+ D DDE PLSSRF  KS  G S+     S + 
Sbjct: 127  KPLSSRFKGSTNNANKGVTVPARVKDEHSD-DDEVPLSSRFAAKSNAGSSSCKTISSSEK 185

Query: 2553 KPLAKKLQHNGSAMRDGQPNKYSNMSNKRPPGEIKSSNQLSVKKPKLSSVTAPTNKKQAS 2374
              L  K+Q NGS  +D Q  K S +  KRP      SNQ   KKPKLS  +     KQ +
Sbjct: 186  ILLVSKIQLNGSTAKDKQ-QKSSAVPTKRPMDNKVPSNQSFAKKPKLSDASTT---KQVT 241

Query: 2373 VKPEPKAEXXXXDHLPISQRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2194
            VK E KA+     HL ISQR+                                       
Sbjct: 242  VKAELKADDDD--HLTISQRMKKASSSSNKSLSVKQNVTKVVSFSSKKTTKNNKKQMQNS 299

Query: 2193 XXXXXXXXXXSGEG--KKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVATMF 2020
                            KKW  L HNGVIFPPPYKPHG+KMLYKGKPVDLTPEQEEVATMF
Sbjct: 300  KYSKSTKVQPGSSDGQKKWKTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMF 359

Query: 2019 AVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSXXXXXXXXXXX 1840
            AVM DT+Y+ KP+F +NF+ DW+ +LGKNHVIQ LE CDF+PIYEWHQ            
Sbjct: 360  AVMKDTEYVQKPQFLQNFWNDWRTLLGKNHVIQKLEACDFNPIYEWHQKEKEKKKQMSTE 419

Query: 1839 XXXXXXXXXXXXXXKYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCDI 1660
                           YMWA V+G KEKVGNFRVEPPGLFRGRGEHPKMGKLK RIRP DI
Sbjct: 420  EKKAVREEKLKQEEMYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKSRIRPSDI 479

Query: 1659 TINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGLSD 1480
            TINIGKDAPIP+CP+PGERWKEV+HDNTVTWLAFWNDPINPKEFKYVFLAASS+LKG SD
Sbjct: 480  TINIGKDAPIPKCPIPGERWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSD 539

Query: 1479 KEKYEKARLLKDYIQGIRAAYTKNFASKDPTKKQIAVATYLIDKLALRAGNEKDDDEADT 1300
            KEKYEKAR LKDYI  IR AYTK+FASKD TK+QIAVATYLIDKLALRAGNEKDDDEADT
Sbjct: 540  KEKYEKARKLKDYIHNIRTAYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADT 599

Query: 1299 VGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSSDLFD 1120
            VGCCTLKV NVE +PPN LKFDFLGKDSIRY+N VEVE  V+KAI+QF+  K+ + DLFD
Sbjct: 600  VGCCTLKVANVECIPPNKLKFDFLGKDSIRYENTVEVELPVYKAIRQFQVAKKPTDDLFD 659

Query: 1119 LLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKEVA 940
             LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+ L  ET+ GDVAEK V+Y  ANK+VA
Sbjct: 660  SLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEKLYEETEDGDVAEKFVIYNQANKQVA 719

Query: 939  IICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPKRN 760
            IICNHQRT+SKSH AQM RL EK+EELK  ++E K+DL R KKGKPPL  K+ADGK KRN
Sbjct: 720  IICNHQRTISKSHDAQMSRLTEKLEELKGTLKEFKTDLDRAKKGKPPL--KDADGKQKRN 777

Query: 759  LNPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIE 580
            L PE++EKKIA TN KIEKME   +TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIE
Sbjct: 778  LTPEAIEKKIATTNQKIEKMELSMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIE 837

Query: 579  KIFNKSLLAKFTWAMDVDPSFRF 511
            KIFNKSLLAKFTWAMDVDP FRF
Sbjct: 838  KIFNKSLLAKFTWAMDVDPQFRF 860