BLASTX nr result
ID: Bupleurum21_contig00016000
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Bupleurum21_contig00016000
(1950 letters)
Database: ./nr
23,641,837 sequences; 8,123,359,852 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gb|ACV71017.1| UPA17 [Capsicum annuum] 310 e-156
ref|XP_002510052.1| conserved hypothetical protein [Ricinus comm... 300 e-153
ref|XP_002301140.1| predicted protein [Populus trichocarpa] gi|2... 298 e-150
ref|XP_003545352.1| PREDICTED: uncharacterized protein LOC100807... 287 e-141
ref|XP_003549367.1| PREDICTED: uncharacterized protein LOC100818... 280 e-136
>gb|ACV71017.1| UPA17 [Capsicum annuum]
Length = 596
Score = 310 bits (795), Expect(2) = e-156
Identities = 168/301 (55%), Positives = 218/301 (72%), Gaps = 8/301 (2%)
Frame = -1
Query: 960 SSASVVQGN---VTSNNLGLQHQ-QLINLQHGDSNPSATHLNSLSRSYLNKANVDEKIQD 793
+SA++ G +SN+L L H QL NLQ +NPS T L RSY K N E+ D
Sbjct: 277 ASAALASGGGAAASSNSLNLSHHSQLCNLQPAVTNPSTTS-PYLERSYTAKENFGERYSD 335
Query: 792 AAGLSTLSRNTALRDNQLLSQKQMNLYQEPSRSEFGLVCSDSLLNPFQKSTSMIT---YD 622
G + +S ++++ Q K+ NLY SR+EFGLVC+DSL+NP K +S++ +
Sbjct: 336 MKGSTIVS--PSVKEPQY---KEQNLYGVTSRAEFGLVCADSLINPLNKKSSLVNCRGFG 390
Query: 621 STKDLNDNQNKSQHS-LRQFMDEWPKNQTERSSISWPATDMQSDRTQLSISIPMAASDFM 445
++ +++D ++KSQH LRQFMD+WPKNQ+++S++SWP D+QSD TQLSISIP+ SDFM
Sbjct: 391 NSDNISDQESKSQHHPLRQFMDDWPKNQSDQSNVSWPDIDLQSDPTQLSISIPVVTSDFM 450
Query: 444 SSTSSPNNENRAVSPLRLSRNLDSTQMGLEMNGMFNDTDQRQASWIPITWENSMGGPLGE 265
SSTSSP N+ S R SR ++TQMGL + + ++ +QRQ SWIPI+WE+SMGGPLGE
Sbjct: 451 SSTSSPANDKLTASSHR-SREHEATQMGLGIGTIISEHNQRQGSWIPISWESSMGGPLGE 509
Query: 264 VLHSTNSSAGDCNNNSALNLMTEGWDSSPRLASSPTGVLQKMTFRSLSNSSAGSSPRTEN 85
VLHSTNSS+GDC NNSALNLMTEGWD SPR+ SSPTGVLQK +F SLSNSSAGSSPR EN
Sbjct: 510 VLHSTNSSSGDCKNNSALNLMTEGWDRSPRMGSSPTGVLQKSSFGSLSNSSAGSSPRAEN 569
Query: 84 N 82
+
Sbjct: 570 S 570
Score = 271 bits (692), Expect(2) = e-156
Identities = 154/273 (56%), Positives = 177/273 (64%), Gaps = 20/273 (7%)
Frame = -3
Query: 1750 MDFGVDVVGL-------VSSDTSTHFADPPDAKLKLYGSGVFKQQKND-----EDEWNSF 1607
MDFGV V GL S +TS FA+ KL LYGS F + + EDEWN
Sbjct: 1 MDFGVVVGGLDSGGGVICSDNTSNMFAETKQQKL-LYGSVGFNKHERSSVVTSEDEWNDK 59
Query: 1606 -RKVAKICDSNADDYTISKGVLQERSNKNGSLFSDGQMLSFSSPNLHP----YSYHNGSS 1442
K+AK D+++SK + LF QMLSF++PN SY+ S
Sbjct: 60 DTKLAK----TTHDFSVSKPTM---------LFQQQQMLSFAAPNNTQNHLTMSYYQHPS 106
Query: 1441 ATPYSRNGGYGSGGLTGANMHGMLSG---PFTPSQWMELQHQALIYKYITANSPVPSNLL 1271
+ G GSG L G NMHG+++G PFTPSQWMEL+HQALIYKYITAN P+P LL
Sbjct: 107 SGFARNTPGCGSGALNGGNMHGLIAGVKGPFTPSQWMELEHQALIYKYITANVPIPPYLL 166
Query: 1270 NPIRKALDSAGFSSFLGAHLGSNTLGWGGYHFGFSNNTDPEPGRCRRTDGKKWRCSRDAV 1091
NPIRKAL+SAGF +F G L SN LGWG +H GFSN+ DPEPGRCRRTDGKKWRCSRDAV
Sbjct: 167 NPIRKALESAGFPTFTG--LRSNALGWGAFHLGFSNSNDPEPGRCRRTDGKKWRCSRDAV 224
Query: 1090 PDQKYCERHVNRGRHRSRKPVEGQTSNSVSGTT 992
DQKYCERH+NRGRHRSRKPVEGQT NS S T
Sbjct: 225 ADQKYCERHMNRGRHRSRKPVEGQTGNSASANT 257
>ref|XP_002510052.1| conserved hypothetical protein [Ricinus communis]
gi|223550753|gb|EEF52239.1| conserved hypothetical
protein [Ricinus communis]
Length = 617
Score = 300 bits (769), Expect(2) = e-153
Identities = 167/310 (53%), Positives = 217/310 (70%), Gaps = 6/310 (1%)
Frame = -1
Query: 993 PLHTTTKFLPTSSASVVQGNVTSNNLGL--QHQQLINLQ-HGDSNPSATHLNSLSRSYLN 823
P+ T + ++S + G+ SNNL + QQL NLQ SN SA L ++R LN
Sbjct: 284 PMSTPSSSSASASVVGLHGSGASNNLIIAQNQQQLKNLQPDSSSNLSADTL--VNRMILN 341
Query: 822 KANVDEKIQDAAGLSTLSRNTALRDNQLLSQKQMNLYQEPSRSEFGLVCSDSLLNPFQKS 643
K N+ E++QD+ LS S L+ + + YQE S+ EFG V DSLLNP Q S
Sbjct: 342 KENLGERLQDSPSLSMQSSKIYLKSKENPFFISKHPYQESSQIEFGHVNFDSLLNPSQNS 401
Query: 642 TSMIT---YDSTKDLNDNQNKSQHSLRQFMDEWPKNQTERSSISWPATDMQSDRTQLSIS 472
+S+I+ + S++D++ + SQHS RQFMD+WPK+Q+++SS+SWP D+QSDRTQLSIS
Sbjct: 402 SSLISCRNFASSQDMSGQETISQHSFRQFMDDWPKSQSDQSSVSWPQLDVQSDRTQLSIS 461
Query: 471 IPMAASDFMSSTSSPNNENRAVSPLRLSRNLDSTQMGLEMNGMFNDTDQRQASWIPITWE 292
IP +DF SSTSSP+NE AVSPLRLSR+LDS Q G ++ +FND Q+QA+W P+ WE
Sbjct: 462 IPNDPTDFKSSTSSPSNEIFAVSPLRLSRDLDSIQTGTGVDIVFNDHKQKQANWRPVPWE 521
Query: 291 NSMGGPLGEVLHSTNSSAGDCNNNSALNLMTEGWDSSPRLASSPTGVLQKMTFRSLSNSS 112
S+GGPLGEVLH++N+SA +C N+S LNL+ E WDSS +L SPTGVLQK TF SLSNSS
Sbjct: 522 TSVGGPLGEVLHNSNNSASECKNSSGLNLLVERWDSSSQLGLSPTGVLQKTTFGSLSNSS 581
Query: 111 AGSSPRTENN 82
AGSSPRTENN
Sbjct: 582 AGSSPRTENN 591
Score = 271 bits (692), Expect(2) = e-153
Identities = 154/285 (54%), Positives = 182/285 (63%), Gaps = 30/285 (10%)
Frame = -3
Query: 1750 MDFGV-DVVGLVSSDTSTHF--------------ADPPDAKLKLYGSGVFKQQKN----D 1628
MDFGV GLV SDT+T + P+ K K YGSG KQ+++ +
Sbjct: 1 MDFGVVGFEGLVGSDTTTTTTTGSSGFASLAAAPSSDPETKQKWYGSGFLKQERSSTTTN 60
Query: 1627 EDEWNSFRKVAKICDSNADDYTISKGVLQERSNKNGSLFSDG---QMLSFSSPNLHPYS- 1460
ED+W S + S + +S + SLF+D QMLSFS P P S
Sbjct: 61 EDDWRSSKL------SKTESMLLSHRSTTLLKSNATSLFTDNGQQQMLSFSCPKPEPPSS 114
Query: 1459 ---YHNGSSATPYSRNGGYGS-GGLTGANMHGMLS---GPFTPSQWMELQHQALIYKYIT 1301
Y + +S+ Y+RN GY + G ANMHG+ + GPFTPSQWMEL+HQALIYKYIT
Sbjct: 115 TLPYFHLTSSAAYNRNTGYMNYGNFNSANMHGVYTEARGPFTPSQWMELEHQALIYKYIT 174
Query: 1300 ANSPVPSNLLNPIRKALDSAGFSSFLGAHLGSNTLGWGGYHFGFSNNTDPEPGRCRRTDG 1121
AN P+PSNLL PIRKALDSAGFSSF G L NTL WG +H GFS+N DPEPGRCRRTDG
Sbjct: 175 ANVPIPSNLLIPIRKALDSAGFSSFSGGLLRPNTLPWGAFHLGFSSNNDPEPGRCRRTDG 234
Query: 1120 KKWRCSRDAVPDQKYCERHVNRGRHRSRKPVEGQTSNSVSGTTIT 986
KKWRCSRDAV DQKYCERH+NRGRHRSRK VEGQ+ +S + T T
Sbjct: 235 KKWRCSRDAVADQKYCERHMNRGRHRSRKHVEGQSGHSAAAATKT 279
>ref|XP_002301140.1| predicted protein [Populus trichocarpa] gi|222842866|gb|EEE80413.1|
predicted protein [Populus trichocarpa]
Length = 605
Score = 298 bits (764), Expect(2) = e-150
Identities = 162/313 (51%), Positives = 217/313 (69%), Gaps = 10/313 (3%)
Frame = -1
Query: 984 TTTKFLPTSSASVVQGNVTSNNLGLQHQQLI--NLQHGDSNPSATHLNSLSRSYLNKANV 811
TT K + ++S +V + I N Q S+ + + N+LSR +L NV
Sbjct: 271 TTLKPMANGTSSFASASVVGLRSAVSDSHTIVHNQQQPASSSNLSATNTLSRVFLATENV 330
Query: 810 DEKIQDAAGLSTLSRNTALRDNQ--LLSQKQMNLYQEPSRSEFGLVCSDSLLNPFQKSTS 637
E++QDA+GLS L + L+ + KQ N Y E ++EF LV SDSLLN QKS+S
Sbjct: 331 GERMQDASGLSMLPSSIDLKSKETPFFISKQQNSYGESLQNEFALVTSDSLLNHSQKSSS 390
Query: 636 MIT---YDSTKDLNDNQNKSQHSLRQFMDEWPKNQTERSSISWPATDMQSDRTQLSISIP 466
+++ + S++DL D ++ SQHSLRQFMD+ PK+ ++RS+++WP D+QS+RTQLSISIP
Sbjct: 391 LMSCRNFGSSQDLTDQESVSQHSLRQFMDDCPKSHSDRSAVAWPGLDLQSERTQLSISIP 450
Query: 465 MAASDFMSSTSSPNNENRAVSPLRLSRNLDSTQMGLEM--NGMFNDTDQRQASWIPITWE 292
MA +DF+SSTSS NNE ++SPLRLSR D +MGL + + N+ +QRQA+WIPI+WE
Sbjct: 451 MAPADFVSSTSSSNNEKISLSPLRLSREFDPIKMGLGVGAGSVANEPNQRQANWIPISWE 510
Query: 291 NSMGGPLGEVLHSTNSSA-GDCNNNSALNLMTEGWDSSPRLASSPTGVLQKMTFRSLSNS 115
SMGGPLGEVLH+TN++A +C N S+LNLMTE WD+SPR+ SSPTGVLQK F SLSNS
Sbjct: 511 TSMGGPLGEVLHNTNNNATAECKNESSLNLMTERWDNSPRVGSSPTGVLQKSAFASLSNS 570
Query: 114 SAGSSPRTENNLL 76
SAGSSPR EN +
Sbjct: 571 SAGSSPRAENKTI 583
Score = 262 bits (669), Expect(2) = e-150
Identities = 156/287 (54%), Positives = 187/287 (65%), Gaps = 34/287 (11%)
Frame = -3
Query: 1750 MDFGVDVV--GLVSSDTSTH-----FADPPDAKLKLYGSGVFKQQKND--EDEWNSFRKV 1598
MDFGV V GLV SDTS + P+AK K YGSG KQ+++ +D+W + K+
Sbjct: 1 MDFGVQVGLDGLVGSDTSNSGFASLASSDPEAKQK-YGSGFLKQERSAAADDDWRN-SKL 58
Query: 1597 AKICDSNADDYTISKGVLQERSN------KNGSLFSDGQ----MLSFSSPN--------- 1475
AK ++ +L ++ N N SLF+DGQ MLSFS P
Sbjct: 59 AK-----------TESMLLDQRNTFLLKSSNNSLFTDGQQQQQMLSFSCPKSASSGERSS 107
Query: 1474 ---LHPYSYHNGSSATPYSRNGGYGSGGLTGANMHGMLSG---PFTPSQWMELQHQALIY 1313
+ PY +H SSA +RN GY SG A+MHG+L+ PFT QWMEL+HQALIY
Sbjct: 108 PNAMLPY-FHLTSSAC--NRNTGYNSGIFNAASMHGVLTETRWPFTQLQWMELEHQALIY 164
Query: 1312 KYITANSPVPSNLLNPIRKALDSAGFSSFLGAHLGSNTLGWGGYHFGFSNNTDPEPGRCR 1133
KY+TAN P+PSNLL PIRKALDSAGFSSF G + L WG +H GFS+NTDPEPGRCR
Sbjct: 165 KYMTANVPIPSNLLIPIRKALDSAGFSSFSGGLFKPSALQWGTFHMGFSSNTDPEPGRCR 224
Query: 1132 RTDGKKWRCSRDAVPDQKYCERHVNRGRHRSRKPVEGQTSNSVSGTT 992
RTDGKKWRCSRDAV DQKYCERH+NRGRHRSRKPVEGQ+ +S + TT
Sbjct: 225 RTDGKKWRCSRDAVADQKYCERHMNRGRHRSRKPVEGQSGHSAAATT 271
>ref|XP_003545352.1| PREDICTED: uncharacterized protein LOC100807080 [Glycine max]
Length = 652
Score = 287 bits (734), Expect(2) = e-141
Identities = 164/293 (55%), Positives = 199/293 (67%), Gaps = 38/293 (12%)
Frame = -3
Query: 1750 MDFGV-DVVGLVSSDTSTHF----ADPPDAKLKLYGSGVFKQQKN----DEDEWNSFRKV 1598
MD GV + G+V S++ F A P+ K K YGSGV KQ+++ ++DEW ++ KV
Sbjct: 59 MDLGVVGLEGVVGSESGCVFGSSLASDPETKHKWYGSGVLKQERSAIASEDDEWGTY-KV 117
Query: 1597 AKICDSNADDYTISKG----VLQERSNK-----NGSLFSDG----QMLSFSSPNLH---- 1469
AKI D+ +S + Q+R+N N +LFSDG QMLSFSSP
Sbjct: 118 AKI------DHDMSSAPKAMIFQQRNNSLLRSNNATLFSDGHHQSQMLSFSSPKSETLLV 171
Query: 1468 ---------PYSYHNGSSATPYSRNGGYGSGGLTGANMHGMLSG---PFTPSQWMELQHQ 1325
P+SYH SS YSRN GY SG ++ MHG L+G PFTPSQWMEL+HQ
Sbjct: 172 DTASSNATLPFSYHQLSS---YSRNTGYSSGSIS---MHGALAGVRGPFTPSQWMELEHQ 225
Query: 1324 ALIYKYITANSPVPSNLLNPIRKALDSAGFSSFLGAHLGSNTLGWGGYHFGFSNNTDPEP 1145
ALIYKYITAN PVP++LL PIRKALDS GF +F L SN+LGWGG+H GFSN+TDPEP
Sbjct: 226 ALIYKYITANMPVPTHLLIPIRKALDSVGFCNFSTGLLRSNSLGWGGFHLGFSNSTDPEP 285
Query: 1144 GRCRRTDGKKWRCSRDAVPDQKYCERHVNRGRHRSRKPVEGQTSNSVSGTTIT 986
GRCRRTDGKKWRCSRDAV DQKYCERH+NRGRHRSRKPVEGQ+ ++++ TT T
Sbjct: 286 GRCRRTDGKKWRCSRDAVVDQKYCERHMNRGRHRSRKPVEGQSGHALTTTTTT 338
Score = 244 bits (622), Expect(2) = e-141
Identities = 162/325 (49%), Positives = 209/325 (64%), Gaps = 24/325 (7%)
Frame = -1
Query: 984 TTTKFLPTSSASVVQGNVTSNNLGLQHQQLINLQHGDSNPSATHLNSLSRSYLNKA---N 814
TT +S+++VV GN T + N H P+++ N+++R ++N +
Sbjct: 338 TTNTLNASSNSTVVPGNNTFAH---------NKVHHPLPPNSSPANTINRMFMNNKENNS 388
Query: 813 VDEKIQDAAGLSTLSRNTALRD---NQLLSQKQMNLYQEPSRS--EFGLVCSDSLLNPFQ 649
E+++D + L L L+ N + K + Y E SR+ EFGLV SDSLLNP Q
Sbjct: 389 TSERMEDCSALPMLPPTLELKPKEKNNFMIHKHQDPYDESSRNNNEFGLVTSDSLLNPTQ 448
Query: 648 KSTSMITYDSTKDLNDNQNKSQHSLRQFMDEWPK---NQTERSSISWPATD-MQSDRTQL 481
K S + S KD D++++ QHSLR F+D+ PK + RSS WP D +QSDRTQL
Sbjct: 449 KR-SFDSSSSQKD--DSESQQQHSLRHFIDDSPKPPSHNHHRSSSIWPELDNIQSDRTQL 505
Query: 480 SISIPMAASDFMS-STSSPNNENRAVSPLRLSRNLDSTQMGLEM-NGMFNDTDQRQASWI 307
SISIP+++SDFMS +TSSP+NE +SPLRLSR LD QMGL + +G N+ + RQA+WI
Sbjct: 506 SISIPISSSDFMSFTTSSPSNEKLTLSPLRLSRALDPIQMGLGVGSGASNEANPRQANWI 565
Query: 306 PITWENSMGGPLGEVLH-STNSSAGD-C--NNNSALNLMTE----GWDSSPRLASSPTGV 151
PITWE+SMGGPLGEVL+ S NS+A D C NN SALNLM + GWD+SP L SSPTGV
Sbjct: 566 PITWESSMGGPLGEVLNLSNNSNASDQCGKNNTSALNLMKDDDDDGWDNSPPLGSSPTGV 625
Query: 150 LQKMTFRSLSNSSAGSSPR--TENN 82
LQK F SLSNSSAGSSPR ENN
Sbjct: 626 LQKTAFGSLSNSSAGSSPRGAPENN 650
>ref|XP_003549367.1| PREDICTED: uncharacterized protein LOC100818860 [Glycine max]
Length = 600
Score = 280 bits (715), Expect(2) = e-136
Identities = 157/288 (54%), Positives = 196/288 (68%), Gaps = 35/288 (12%)
Frame = -3
Query: 1750 MDFGV-DVVGLVSSDTSTHFADP----PDAKLKLYGSGVFKQQKN----DEDEWNSFRKV 1598
MD GV + G+V S++ F P+ K K YGSG+ KQ+++ ++DEW ++
Sbjct: 1 MDLGVVGLEGVVGSESGCVFGSSLVSDPETKHKWYGSGLLKQERSAIATEDDEW----RI 56
Query: 1597 AKICDSNADDYTISKGVL-QERSNK-----NGSLFSDG----QMLSFSSPNLH------- 1469
+K+ ++ D + SK +L Q+R+N N +LFSDG QMLSFSSP
Sbjct: 57 SKVAKTDHDMSSASKAMLFQQRNNSLLRSNNATLFSDGHHQSQMLSFSSPKSDSLLIDKA 116
Query: 1468 ------PYSYHNGSSATPYSRNGGYGSGGLTGANMHGMLS---GPFTPSQWMELQHQALI 1316
P+S H SS Y+RN GY SG ++ MHG L+ GPFTPSQWMEL+HQALI
Sbjct: 117 SSNATLPFSSHQLSS---YTRNTGYNSGSIS---MHGALASVRGPFTPSQWMELEHQALI 170
Query: 1315 YKYITANSPVPSNLLNPIRKALDSAGFSSFLGAHLGSNTLGWGGYHFGFSNNTDPEPGRC 1136
YKYITAN PVP++LL PIRKALDS GF +F L N+LGWGG+H GFSNNTDPEPGRC
Sbjct: 171 YKYITANVPVPTHLLIPIRKALDSVGFCNFSAGLLRPNSLGWGGFHLGFSNNTDPEPGRC 230
Query: 1135 RRTDGKKWRCSRDAVPDQKYCERHVNRGRHRSRKPVEGQTSNSVSGTT 992
RRTDGKKWRCSRDAV DQKYCERH+NRGRHRSRKPVEGQ+ ++++ TT
Sbjct: 231 RRTDGKKWRCSRDAVVDQKYCERHMNRGRHRSRKPVEGQSGHALTTTT 278
Score = 234 bits (597), Expect(2) = e-136
Identities = 159/332 (47%), Positives = 208/332 (62%), Gaps = 26/332 (7%)
Frame = -1
Query: 990 LHTTTKFLPTSSA-SVVQGNVTSNNLGLQHQQLINLQHGDSNPSATHLNSLSRSYL---- 826
L TTT P +S+ SVV GN NN H + H P ++ +N+++R +
Sbjct: 274 LTTTTSNTPNASSNSVVPGN---NNNTFAHNNV----HHPIPPHSSPVNTITRMFTSNKE 326
Query: 825 NKANVDEKIQDAAGLSTLSRNTALR---DNQLLSQKQM---NLYQEPSRSEFGLVCSDSL 664
N + E++QD A L L L+ +N + K + Y + +EFGLV SDSL
Sbjct: 327 NNNSTSERMQDPA-LPMLPPTLELKPKENNPFMIHKHQIPSDEYSSRNNNEFGLVTSDSL 385
Query: 663 LNPFQKSTSMITYDSTKDLNDNQNKSQHSLRQFMDEWPKNQTE---RSSISWPATD-MQS 496
LNP +K + + S++ + ++++ QHSLR F+D+ PK Q+ RSS WP D MQS
Sbjct: 386 LNPSEKRS----FTSSQKNDSSESQQQHSLRHFIDDSPKPQSNHHHRSSSIWPELDNMQS 441
Query: 495 DRTQLSISIPMAASD-FMSSTSS-PNNENRAVSPLRLSRNLDSTQMGLEMNGMFNDTDQR 322
DRTQLSISIP+++SD FMS T+S P+NE +SPLRLSR LD QMGL + N+ + R
Sbjct: 442 DRTQLSISIPISSSDHFMSFTTSLPSNEKLTLSPLRLSRELDPIQMGLGVGSAPNEANTR 501
Query: 321 QASWIPITWENSMGGPLGEVL---HSTNSSAGD-C----NNNSALNLMTEGWDSSPRLAS 166
QA+WIPITWE+SMGGPLGEVL ++ NS+A D C NN SALNLM +GWD++P S
Sbjct: 502 QANWIPITWESSMGGPLGEVLNLSNNNNSNASDQCGKNNNNTSALNLMKDGWDNNPPSGS 561
Query: 165 SPTGVLQKMTFRSLSNSSAGSSPR-TENNLLG 73
SPTGVLQK F SLSNSSAGSSPR ENN G
Sbjct: 562 SPTGVLQKSAFGSLSNSSAGSSPRGAENNKEG 593