BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Bupleurum21_contig00002752
         (3607 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002512412.1| acyl-CoA binding protein, putative [Ricinus ...   885   0.0  
emb|CBI39496.3| unnamed protein product [Vitis vinifera]              879   0.0  
ref|XP_002284019.1| PREDICTED: acyl-CoA-binding domain-containin...   877   0.0  
gb|AFZ62126.1| acyl-CoA binding protein 4 [Vernicia fordii]           853   0.0  
ref|XP_004144782.1| PREDICTED: acyl-CoA-binding domain-containin...   837   0.0  

>ref|XP_002512412.1| acyl-CoA binding protein, putative [Ricinus communis]
            gi|223548373|gb|EEF49864.1| acyl-CoA binding protein,
            putative [Ricinus communis]
          Length = 675

 Score =  885 bits (2287), Expect = 0.0
 Identities = 440/572 (76%), Positives = 499/572 (87%), Gaps = 3/572 (0%)
 Frame = +3

Query: 1548 SWNGLENMASTEAMRLFVKILEEEDPGWYSRASNLVSEPIQDIEINKNPKIETAIENGSA 1727
            SW GL NMASTEAMRLFVKILEEEDPGWYSRASN V EP+ D+++N NPK+E+ +ENG++
Sbjct: 78   SWQGLGNMASTEAMRLFVKILEEEDPGWYSRASNSVPEPVVDMQLNHNPKVESIVENGNS 137

Query: 1728 LPEMKTIPTENGNVLEAQDKDVVMVGIGSVAVYDQWITPPVSGPRPKARYEHGATVIDDK 1907
             PE KTI +ENGNV+E QDKDVV  G+GSVAVYDQWITPP+SG RPKARYEHGA V+ DK
Sbjct: 138  YPETKTISSENGNVIETQDKDVVSEGLGSVAVYDQWITPPISGQRPKARYEHGAAVVQDK 197

Query: 1908 MYVYGGNHNGRYLNDLQVLDLRNWTWSRVEVKAPPVALEP-SSFTSSPCAGHSLIPWGRD 2084
            MY+YGGNHNGRYLNDL VLDLR+W+WS+V+ K    + E  SS T +PCAGHSLI W  +
Sbjct: 198  MYIYGGNHNGRYLNDLHVLDLRSWSWSKVDAKVEAESNESKSSPTLTPCAGHSLISW-EN 256

Query: 2085 KLLSIAGHTKDPSESMQVKVFDLQTCSWSALKTYGKPPVSRGGQSVTLVGTSVVIFGGED 2264
            KLLSIAGHTKDPSE MQVKVFDLQT +WS LKTYGKPPVSRGGQSVTLVGTS+VIFGG+D
Sbjct: 257  KLLSIAGHTKDPSEYMQVKVFDLQTRTWSTLKTYGKPPVSRGGQSVTLVGTSLVIFGGQD 316

Query: 2265 AKRSLLNDLHILDLETLTWDEIDTLGVPPSPRSDHAAAVHADRYLLIFGGGSHATCFNDL 2444
            AKRSLLNDLHILDLE++TWDEID +GVPPSPRSDHAAAVHA+RY+LIFGGGSHATCFNDL
Sbjct: 317  AKRSLLNDLHILDLESMTWDEIDAVGVPPSPRSDHAAAVHAERYILIFGGGSHATCFNDL 376

Query: 2445 HVLDLQTMEWSRPSQQGELPSPRAGHAGATVGESWFIAGGGDNKSGVSETVVLNMSTLSW 2624
            HVLD + MEW+RP+QQG+LPSPRAGHAG TVGE+WFIAGGGDNKSGVSET+VLNMSTL W
Sbjct: 377  HVLDSKNMEWTRPTQQGKLPSPRAGHAGVTVGENWFIAGGGDNKSGVSETIVLNMSTLVW 436

Query: 2625 SVVTTVQGRVPLASEGLSLVLSSCSGEDILISFGGYNGRYSNEVHVLKPSHKSSLQSKL- 2801
            SVVT+V+GRVPLASEGLSL++SS +GEDIL+SFGGYNGRYSN+V+VLKPSHKS+LQSK+ 
Sbjct: 437  SVVTSVEGRVPLASEGLSLMVSSYNGEDILVSFGGYNGRYSNDVNVLKPSHKSTLQSKII 496

Query: 2802 -TPVPDSVSAVNNDTNATRDVESEIEAGQEGKIREIVMDNVDLKPKIKNIKQTSEQTLAA 2978
             TPVPDSVSAV+N TNATRD+ESE EAGQEGKIREIVMDNVD +P     + +SE  LA 
Sbjct: 497  ETPVPDSVSAVHNATNATRDLESESEAGQEGKIREIVMDNVDPEPMKSKGEVSSEHLLAT 556

Query: 2979 LKAERDDLESSLSKEKLQAMQLKNQLEEAESRNTDLYKELQSVRGQLASEQSRCFKLEVD 3158
            LKAE+++LESSLSKEK Q +QLK +L EAE+RNTDLYKELQSVR QLA+EQSRCFKLEVD
Sbjct: 557  LKAEKEELESSLSKEKFQTLQLKQELAEAETRNTDLYKELQSVRSQLAAEQSRCFKLEVD 616

Query: 3159 VAELRQKXXXXXXXXXXXXXXXRQKAASEEAA 3254
            VAELRQK               RQKAASE+AA
Sbjct: 617  VAELRQKLQTMETLQKELELLQRQKAASEQAA 648


>emb|CBI39496.3| unnamed protein product [Vitis vinifera]
          Length = 674

 Score =  879 bits (2271), Expect = 0.0
 Identities = 434/571 (76%), Positives = 498/571 (87%), Gaps = 2/571 (0%)
 Frame = +3

Query: 1545 SSWNGLENMASTEAMRLFVKILEEEDPGWYSRASNLVSEPIQDIEINKNPKIETAIENGS 1724
            +SW+GL NMA+ EAMRLFVKILEEEDPGWYSRAS+ V+EP+ D+E+N +PK+E   ENG+
Sbjct: 79   TSWHGLGNMAAAEAMRLFVKILEEEDPGWYSRASDFVAEPVVDVEMNHHPKVEPVTENGN 138

Query: 1725 ALPEMKTIPTENGNVLEAQDKDVVMVGIGSVAVYDQWITPPVSGPRPKARYEHGATVIDD 1904
            + PE KTI  ENG++LE QDKDVV+ G+GS+AVYDQWI P VSG RPK RYEHGA V+ D
Sbjct: 139  SFPETKTISHENGSMLETQDKDVVLEGLGSIAVYDQWIAPSVSGQRPKPRYEHGAAVVQD 198

Query: 1905 KMYVYGGNHNGRYLNDLQVLDLRNWTWSRVEVKAPPVALE-PSSFTSSPCAGHSLIPWGR 2081
            KMY++GGNHNGRYLNDLQVLDLR+WTWS+VEVKA   +LE PS+     CAGHSLI W  
Sbjct: 199  KMYIFGGNHNGRYLNDLQVLDLRSWTWSKVEVKAGTESLESPSTVPLPSCAGHSLIQW-E 257

Query: 2082 DKLLSIAGHTKDPSESMQVKVFDLQTCSWSALKTYGKPPVSRGGQSVTLVGTSVVIFGGE 2261
            +KLLSIAGHTKDPSE++QVK FDLQTC+WS LKTYGK P SRGGQSVTLVGTS+VIFGG+
Sbjct: 258  NKLLSIAGHTKDPSETIQVKAFDLQTCTWSTLKTYGKAPASRGGQSVTLVGTSLVIFGGQ 317

Query: 2262 DAKRSLLNDLHILDLETLTWDEIDTLGVPPSPRSDHAAAVHADRYLLIFGGGSHATCFND 2441
            DAKRSLLNDLH+LDLET+TWDEID +GVPPSPRSDHAAAVHA+RYLLIFGGGSHATCFND
Sbjct: 318  DAKRSLLNDLHLLDLETMTWDEIDAVGVPPSPRSDHAAAVHAERYLLIFGGGSHATCFND 377

Query: 2442 LHVLDLQTMEWSRPSQQGELPSPRAGHAGATVGESWFIAGGGDNKSGVSETVVLNMSTLS 2621
            LHVLDLQ MEWSRP+QQG++P+PRAGHAG  VGE+WFI GGGDNKSGVSETVVLNMSTL 
Sbjct: 378  LHVLDLQAMEWSRPTQQGDIPTPRAGHAGVPVGENWFIVGGGDNKSGVSETVVLNMSTLV 437

Query: 2622 WSVVTTVQGRVPLASEGLSLVLSSCSGEDILISFGGYNGRYSNEVHVLKPSHKSSLQSK- 2798
            WSVVTTVQGRVPLASEGLSLV+ S +GED+LISFGGYNGRYSNEV+VLKPSHKSSLQ+K 
Sbjct: 438  WSVVTTVQGRVPLASEGLSLVVGSYNGEDVLISFGGYNGRYSNEVNVLKPSHKSSLQTKI 497

Query: 2799 LTPVPDSVSAVNNDTNATRDVESEIEAGQEGKIREIVMDNVDLKPKIKNIKQTSEQTLAA 2978
            + PVP+SVSAV+N TNATRDVESE EAGQEGKIREIVMDN+D +P IKN ++T E  +A 
Sbjct: 498  MEPVPESVSAVHNATNATRDVESEFEAGQEGKIREIVMDNIDSEPMIKN-EETGEGLIAT 556

Query: 2979 LKAERDDLESSLSKEKLQAMQLKNQLEEAESRNTDLYKELQSVRGQLASEQSRCFKLEVD 3158
            LK+E+++LESSL+KEK Q++QLK +L EAE+RN+DLYKELQSVRGQLA+EQSRCFKLEVD
Sbjct: 557  LKSEKEELESSLNKEKTQSLQLKQELAEAETRNSDLYKELQSVRGQLAAEQSRCFKLEVD 616

Query: 3159 VAELRQKXXXXXXXXXXXXXXXRQKAASEEA 3251
            VAELRQK               RQKAASE+A
Sbjct: 617  VAELRQKLQTMETLQKELELLQRQKAASEQA 647


>ref|XP_002284019.1| PREDICTED: acyl-CoA-binding domain-containing protein 4-like isoform
            1 [Vitis vinifera]
          Length = 675

 Score =  877 bits (2265), Expect = 0.0
 Identities = 435/572 (76%), Positives = 499/572 (87%), Gaps = 3/572 (0%)
 Frame = +3

Query: 1545 SSWNGLENMASTEAMRLFVKILEEEDPGWYSRASNLVSEPIQDIEINKNPKIETAIENGS 1724
            +SW+GL NMA+ EAMRLFVKILEEEDPGWYSRAS+ V+EP+ D+E+N +PK+E   ENG+
Sbjct: 79   TSWHGLGNMAAAEAMRLFVKILEEEDPGWYSRASDFVAEPVVDVEMNHHPKVEPVTENGN 138

Query: 1725 ALPEMKTIPTENGNVLEAQDKDVVMVGIGSVAVYDQWITPPVSGPRPKARYEHGATVIDD 1904
            + PE KTI  ENG++LE QDKDVV+ G+GS+AVYDQWI P VSG RPK RYEHGA V+ D
Sbjct: 139  SFPETKTISHENGSMLETQDKDVVLEGLGSIAVYDQWIAPSVSGQRPKPRYEHGAAVVQD 198

Query: 1905 KMYVYGGNHNGRYLNDLQVLDLRNWTWSRVEVKAPPVALE-PSSFTSSPCAGHSLIPWGR 2081
            KMY++GGNHNGRYLNDLQVLDLR+WTWS+VEVKA   +LE PS+     CAGHSLI W  
Sbjct: 199  KMYIFGGNHNGRYLNDLQVLDLRSWTWSKVEVKAGTESLESPSTVPLPSCAGHSLIQW-E 257

Query: 2082 DKLLSIAGHTKDPSESMQVKVFDLQTCSWSALKTYGKPPVSRGGQSVTLVGTSVVIFGGE 2261
            +KLLSIAGHTKDPSE++QVK FDLQTC+WS LKTYGK P SRGGQSVTLVGTS+VIFGG+
Sbjct: 258  NKLLSIAGHTKDPSETIQVKAFDLQTCTWSTLKTYGKAPASRGGQSVTLVGTSLVIFGGQ 317

Query: 2262 DAKRSLLNDLHILDLETLTWDEIDTLGVPPSPRSDHAAAVHADRYLLIFGGGSHATCFND 2441
            DAKRSLLNDLH+LDLET+TWDEID +GVPPSPRSDHAAAVHA+RYLLIFGGGSHATCFND
Sbjct: 318  DAKRSLLNDLHLLDLETMTWDEIDAVGVPPSPRSDHAAAVHAERYLLIFGGGSHATCFND 377

Query: 2442 LHVLDLQTMEWSRPSQQGELPSPRAGHAGATVGESWFIAGGGDNKSGVSETVVLNMSTLS 2621
            LHVLDLQ MEWSRP+QQG++P+PRAGHAG  VGE+WFI GGGDNKSGVSETVVLNMSTL 
Sbjct: 378  LHVLDLQAMEWSRPTQQGDIPTPRAGHAGVPVGENWFIVGGGDNKSGVSETVVLNMSTLV 437

Query: 2622 WSVVTTVQGRVPLASEGLSLVLSSCSGEDILISFGGYNGRYSNEVHVLKPSHKSSLQSK- 2798
            WSVVTTVQGRVPLASEGLSLV+ S +GED+LISFGGYNGRYSNEV+VLKPSHKSSLQ+K 
Sbjct: 438  WSVVTTVQGRVPLASEGLSLVVGSYNGEDVLISFGGYNGRYSNEVNVLKPSHKSSLQTKI 497

Query: 2799 LTPVPDSVSAVNNDTNATRDVESEIEAGQEGKIREIVMDNVDLKP-KIKNIKQTSEQTLA 2975
            + PVP+SVSAV+N TNATRDVESE EAGQEGKIREIVMDN+D +P KIKN ++T E  +A
Sbjct: 498  MEPVPESVSAVHNATNATRDVESEFEAGQEGKIREIVMDNIDSEPMKIKN-EETGEGLIA 556

Query: 2976 ALKAERDDLESSLSKEKLQAMQLKNQLEEAESRNTDLYKELQSVRGQLASEQSRCFKLEV 3155
             LK+E+++LESSL+KEK Q++QLK +L EAE+RN+DLYKELQSVRGQLA+EQSRCFKLEV
Sbjct: 557  TLKSEKEELESSLNKEKTQSLQLKQELAEAETRNSDLYKELQSVRGQLAAEQSRCFKLEV 616

Query: 3156 DVAELRQKXXXXXXXXXXXXXXXRQKAASEEA 3251
            DVAELRQK               RQKAASE+A
Sbjct: 617  DVAELRQKLQTMETLQKELELLQRQKAASEQA 648


>gb|AFZ62126.1| acyl-CoA binding protein 4 [Vernicia fordii]
          Length = 669

 Score =  853 bits (2205), Expect = 0.0
 Identities = 429/569 (75%), Positives = 484/569 (85%), Gaps = 1/569 (0%)
 Frame = +3

Query: 1548 SWNGLENMASTEAMRLFVKILEEEDPGWYSRASNLVSEPIQDIEINKNPKIETAIENGSA 1727
            SWNGL NMASTEAMRLFVKILEEEDPGWYSRASN V EP+ D+++N NPK +  +ENG++
Sbjct: 77   SWNGLANMASTEAMRLFVKILEEEDPGWYSRASNFVLEPVVDMQMNHNPKADPVVENGNS 136

Query: 1728 LPEMKTIPTENGNVLEAQDKDVVMVGIGSVAVYDQWITPPVSGPRPKARYEHGATVIDDK 1907
             PE KTI +ENG V+E QDKDVV  G+GSVAVYDQWI PP+SG  PKARYEHGA VI D+
Sbjct: 137  FPETKTISSENGTVIETQDKDVVSEGLGSVAVYDQWIAPPISGQCPKARYEHGAVVIQDQ 196

Query: 1908 MYVYGGNHNGRYLNDLQVLDLRNWTWSRVEVKAPPVALEPSS-FTSSPCAGHSLIPWGRD 2084
            MY+YGGNHNGRYLNDL VLDLR+WTWS+V+ K    + E  S  T +PCAGHSLIPW  +
Sbjct: 197  MYIYGGNHNGRYLNDLHVLDLRSWTWSKVDAKVEAESDESKSPATVTPCAGHSLIPW-EN 255

Query: 2085 KLLSIAGHTKDPSESMQVKVFDLQTCSWSALKTYGKPPVSRGGQSVTLVGTSVVIFGGED 2264
            KLLSIAGHTKDPSES+QVK FD Q  SWS LKTYGK PVSRGGQSVTLVGT++VIFGG+D
Sbjct: 256  KLLSIAGHTKDPSESIQVKAFDPQNRSWSTLKTYGKAPVSRGGQSVTLVGTNLVIFGGQD 315

Query: 2265 AKRSLLNDLHILDLETLTWDEIDTLGVPPSPRSDHAAAVHADRYLLIFGGGSHATCFNDL 2444
            AKRSLLNDLHILDLET+TWDEID +G PPSPRSDHAAAVHA+RYLLIFGGGSHATCFNDL
Sbjct: 316  AKRSLLNDLHILDLETMTWDEIDAVGGPPSPRSDHAAAVHAERYLLIFGGGSHATCFNDL 375

Query: 2445 HVLDLQTMEWSRPSQQGELPSPRAGHAGATVGESWFIAGGGDNKSGVSETVVLNMSTLSW 2624
            HVLDLQ MEW+RP QQGE+PSPRAGHAG TVGE+WFI GGGDNKSGVSETVVLNMSTL W
Sbjct: 376  HVLDLQAMEWTRPIQQGEIPSPRAGHAGVTVGENWFIVGGGDNKSGVSETVVLNMSTLVW 435

Query: 2625 SVVTTVQGRVPLASEGLSLVLSSCSGEDILISFGGYNGRYSNEVHVLKPSHKSSLQSKLT 2804
            SVVT+V+GRVPLASEGLSLV+SS +GEDIL+SFGGYNGRYSN+V+VLKPSHKS+ +   T
Sbjct: 436  SVVTSVEGRVPLASEGLSLVVSSYNGEDILVSFGGYNGRYSNDVNVLKPSHKST-KIMET 494

Query: 2805 PVPDSVSAVNNDTNATRDVESEIEAGQEGKIREIVMDNVDLKPKIKNIKQTSEQTLAALK 2984
            PV DSVSAV+N TNATRD+ESE +  QEGKIREIVMDNVD +P     + +SE  +A+LK
Sbjct: 495  PVLDSVSAVHNATNATRDLESEFD--QEGKIREIVMDNVDAEPMKSKGEVSSEHRIASLK 552

Query: 2985 AERDDLESSLSKEKLQAMQLKNQLEEAESRNTDLYKELQSVRGQLASEQSRCFKLEVDVA 3164
             E+++LESSLSKEKLQ +QLK +L EAE+RNTDLYKELQSVRGQLA+EQSRCFKLEVDVA
Sbjct: 553  GEKEELESSLSKEKLQTLQLKQELAEAETRNTDLYKELQSVRGQLAAEQSRCFKLEVDVA 612

Query: 3165 ELRQKXXXXXXXXXXXXXXXRQKAASEEA 3251
            ELRQK               RQKAASE+A
Sbjct: 613  ELRQKFQTMEALQKELELLQRQKAASEQA 641


>ref|XP_004144782.1| PREDICTED: acyl-CoA-binding domain-containing protein 4-like [Cucumis
            sativus] gi|449526493|ref|XP_004170248.1| PREDICTED:
            acyl-CoA-binding domain-containing protein 4-like
            [Cucumis sativus]
          Length = 671

 Score =  837 bits (2162), Expect = 0.0
 Identities = 417/596 (69%), Positives = 491/596 (82%), Gaps = 6/596 (1%)
 Frame = +3

Query: 1482 RCNAPQKR--HIIICMEPAKILVSSWNGLENMASTEAMRLFVKILEEEDPGWYSRASNLV 1655
            RCN P+    H I      K    SW+GL NM   EAMRLFVKILEEE+PGWYSR S+ V
Sbjct: 60   RCNVPEPSSWHAI-----EKSKWKSWDGLGNMVPAEAMRLFVKILEEEEPGWYSRVSSFV 114

Query: 1656 SEP--IQDIEINKNPKIETAIENGSALPEMKTIPTENGNVLEAQDKDVVMVGIGSVAVYD 1829
             EP  I D++IN +PKIE  IENG+++PE K I TENG++ E QDKDV++ G+GS+ VYD
Sbjct: 115  PEPEPILDVQINNDPKIEPIIENGNSIPETKNISTENGSLPETQDKDVLVEGLGSIVVYD 174

Query: 1830 QWITPPVSGPRPKARYEHGATVIDDKMYVYGGNHNGRYLNDLQVLDLRNWTWSRVEVKAP 2009
            QWI+PPVSG RPKARYEHGA VI DKMY++GGNHNGRYL+DL VLDLR+W W+++E K  
Sbjct: 175  QWISPPVSGLRPKARYEHGAAVIQDKMYIFGGNHNGRYLSDLHVLDLRSWAWTKLEAKTQ 234

Query: 2010 PVALEPSSFTSSPCAGHSLIPWGRDKLLSIAGHTKDPSESMQVKVFDLQTCSWSALKTYG 2189
                 P   T  PCAGHSLIPW  +KLLS+AGHTKDPS+++QV+VFD+QT +WS LKTYG
Sbjct: 235  SPESPPEKLT--PCAGHSLIPW-ENKLLSVAGHTKDPSDAIQVRVFDVQTSTWSNLKTYG 291

Query: 2190 KPPVSRGGQSVTLVGTSVVIFGGEDAKRSLLNDLHILDLETLTWDEIDTLGVPPSPRSDH 2369
            KPP SRGGQSVTLVGTSVVIFGG+DAKR+LLNDLHILDLET+TWDEID +G PPSPRSDH
Sbjct: 292  KPPASRGGQSVTLVGTSVVIFGGQDAKRTLLNDLHILDLETMTWDEIDAVGAPPSPRSDH 351

Query: 2370 AAAVHADRYLLIFGGGSHATCFNDLHVLDLQTMEWSRPSQQGELPSPRAGHAGATVGESW 2549
            AAAVHA+RYLLIFGGGSHATCFNDLHVLDLQ MEWSRP+QQG++P+PRAGHAG TVGE+W
Sbjct: 352  AAAVHAERYLLIFGGGSHATCFNDLHVLDLQAMEWSRPTQQGDIPTPRAGHAGVTVGENW 411

Query: 2550 FIAGGGDNKSGVSETVVLNMSTLSWSVVTTVQGRVPLASEGLSLVLSSCSGEDILISFGG 2729
            FI GGGDNK+GVSET VLNMSTL WSVVT+VQGRVP+ASEG+SLV+SS  GEDIL+SFGG
Sbjct: 412  FIVGGGDNKNGVSETAVLNMSTLVWSVVTSVQGRVPIASEGISLVVSSYGGEDILVSFGG 471

Query: 2730 YNGRYSNEVHVLKPSHKSSLQSKL--TPVPDSVSAVNNDTNATRDVESEIEAGQEGKIRE 2903
            YNGRY+NEV+VLKPSHKS+LQSK+  TPVPDSVSAV+N TN TRDVESE E  QEGKIRE
Sbjct: 472  YNGRYTNEVNVLKPSHKSTLQSKMMATPVPDSVSAVHNITNPTRDVESEFEGAQEGKIRE 531

Query: 2904 IVMDNVDLKPKIKNIKQTSEQTLAALKAERDDLESSLSKEKLQAMQLKNQLEEAESRNTD 3083
            IVMDN++    +KN  + +++ ++ LKAE+++LESSL+KEK+ ++QLK +L +AE+RN +
Sbjct: 532  IVMDNIE-SDHLKNKSEPTKELVSTLKAEKEELESSLNKEKIHSLQLKQELSDAENRNDE 590

Query: 3084 LYKELQSVRGQLASEQSRCFKLEVDVAELRQKXXXXXXXXXXXXXXXRQKAASEEA 3251
            LYKELQSVR QL +EQSRCFKLEVDVAELRQK               RQKAASEEA
Sbjct: 591  LYKELQSVRLQLVAEQSRCFKLEVDVAELRQKLQTMETLQKELDLLQRQKAASEEA 646