BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Atractylodes21_contig00009546
         (4683 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2-like [Vitis v...  1750   0.0  
emb|CBI24922.3| unnamed protein product [Vitis vinifera]             1721   0.0  
ref|XP_002314046.1| predicted protein [Populus trichocarpa] gi|2...  1675   0.0  
gb|AAN85207.1| DNA topoisomerase II [Nicotiana tabacum] gi|26984...  1640   0.0  
dbj|BAE06274.1| topoisomerase II [Scutellaria baicalensis]           1614   0.0  

>ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2-like [Vitis vinifera]
          Length = 1489

 Score = 1750 bits (4532), Expect = 0.0
 Identities = 916/1516 (60%), Positives = 1094/1516 (72%), Gaps = 24/1516 (1%)
 Frame = +2

Query: 71   MATGQRRPLQSSTTDNIPPTTKPSTGAANKTGRTIEETYQKKTQLEHILLRPDTYIGSIE 250
            MA   + PLQSS   N+P         A   G+TIEETYQKK+QLEHILLRPDTYIGSIE
Sbjct: 1    MAVDNKLPLQSSNNANMP---------AKPAGKTIEETYQKKSQLEHILLRPDTYIGSIE 51

Query: 251  KHEQTLWVWEGDQMVKKQISYVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVEKNLI 430
            KH Q LWV+E ++MV + +SYVPGLYKIFDEILVNAADNKQRDP MDSVKV IDVEKN I
Sbjct: 52   KHTQALWVFENNEMVHRSVSYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEKNCI 111

Query: 431  SVYNNGDGIPVEIHQEEGVYVPELIFGHLLTSSNYDDSIKKTTGGRNGYGAKLANIFSTE 610
            SVYNNGDG+PVEIHQEEGVYVPE+IFGHLLTSSNYDD +KKTTGGRNGYGAKL NIFSTE
Sbjct: 112  SVYNNGDGVPVEIHQEEGVYVPEMIFGHLLTSSNYDDDVKKTTGGRNGYGAKLTNIFSTE 171

Query: 611  FIIETADGKRNRRYKQVFSNNMGKKSEPTITKCKSGENWTMVTFQPDLSKFGMECLEDDV 790
            F+IETADG+R ++YKQVFSNNMGKKSEP ITKCK  ENWT V+F+PDL+KF M  LEDDV
Sbjct: 172  FVIETADGRRQKKYKQVFSNNMGKKSEPVITKCKERENWTKVSFKPDLAKFNMTHLEDDV 231

Query: 791  VALMKKRVVDLAGCLGKTVKVELDGKRVPPKTFEDYVKLYLQSSNETF-----RLYEKVN 955
            VALMKKRVVD+AGCLGKTVKVEL+G+R+P K+F DYV LYLQS+ ++      R+ EKVN
Sbjct: 232  VALMKKRVVDIAGCLGKTVKVELNGQRIPVKSFNDYVNLYLQSAAKSRPESLPRIAEKVN 291

Query: 956  ERWEVCVSLADGHFEQVSFVNNIATIKGGTHVDYITNQIANHIVAVVKKQNKHATLKAHN 1135
            ERWE+CVSL++G F+QVSFVN+IATIKGGTHVDY+TNQIAN ++++V K+NK+A +KAH 
Sbjct: 292  ERWEICVSLSEGQFQQVSFVNSIATIKGGTHVDYVTNQIANFVMSIVNKKNKNANIKAHT 351

Query: 1136 VKNYLWVFVNALIDNPAFDSQTKETLTIKQSSFGSTCELTPEFLKKVAKSDIVKRVVSWV 1315
            VKN+LWVFVNALIDNPAFDSQTKETLTI+QSSFGS CEL+ EFLKKV+KS +V+ ++SW 
Sbjct: 352  VKNHLWVFVNALIDNPAFDSQTKETLTIRQSSFGSKCELSQEFLKKVSKSGVVESLLSWA 411

Query: 1316 QFKQQNDLKKTDGNKRGKLN-IPKLEEANYAATNNSDNCTLILTEGDSAKALAMSGLSVV 1492
             +KQ  DLKKTDG KR +L  I KLE+AN A   NS+ CTLILTEGDSAKALAM+G+SVV
Sbjct: 412  DYKQNKDLKKTDGTKRQRLTGITKLEDANDAGGRNSEKCTLILTEGDSAKALAMAGISVV 471

Query: 1493 GQDFYGVFPLRGKLLNVREASHKQLQENAEIENIKKILGLQTGKVYDNVKSLRYGHLMIM 1672
            G++ YGVFPLRGKLLNVR+A  KQ+ ENAEI+NIK+ILGLQ GK YD++KSLRYGHLMIM
Sbjct: 472  GRNHYGVFPLRGKLLNVRDAQKKQILENAEIQNIKQILGLQQGKEYDSIKSLRYGHLMIM 531

Query: 1673 ADQDHDGSHIKGLLINFLHSFWPSLLKVPNFVLEFITPIVKATNKKTKNVLSFYTMPEYE 1852
             DQDHDGSHIKGLLINF+HSFWPSLLK+P+F++EFITPIVKAT++  + VLSFY+MPEYE
Sbjct: 532  TDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHRNGR-VLSFYSMPEYE 590

Query: 1853 AWKENLGHRARDYKIKYYKGLGTSNGKEGAEYFADLEKHKKDFVWADDEDGDAIELAFSK 2032
            +WKE+LG  A  + IKYYKGLGTS  KEG EYF DL KHKKDF+W D++DGDAIELAFSK
Sbjct: 591  SWKESLGGNASGWSIKYYKGLGTSTSKEGKEYFKDLGKHKKDFMWVDEKDGDAIELAFSK 650

Query: 2033 KKIEARKNWLRALQAGTYFDSKEKHIPYRDFINKELILFSMADLQRSIPSMVDGLKPGQR 2212
            KKIE RKNWLR  Q GTY D KEK I Y DF+NKELILFSMADLQRSIPSMVDGLKPGQR
Sbjct: 651  KKIEERKNWLRQFQPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQR 710

Query: 2213 KILFCAFKKPIFQEVKVAQFSGYVSEHSAYHHGEQSLVSTIIGMAQNFVGSNNINLLYPS 2392
            KILFC+FK+   +E K+AQFSGYVSEHSAYHHGEQSL STIIGMAQ+FVGSNNINLL P+
Sbjct: 711  KILFCSFKRNFIKEAKIAQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPN 770

Query: 2393 GQFGTRQMGGKDHASGRYIYTRLSPITRHLFHKADELLLNYLNEDGQSIEPTWFIPIIPM 2572
            GQFGTR  GGKDHAS RYIYTRLSPITR LF K D++LL+YLNEDGQSIEPTW++P IPM
Sbjct: 771  GQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDILLDYLNEDGQSIEPTWYVPTIPM 830

Query: 2573 VLVNGSEGIGTGWSSFVPNYNPREIIANLKRLLNGEAMVPMDPWYKWFKGTIQK---TAA 2743
            VLVNGSEGIGTGWSS +PNYNPR+IIAN++RLLNGE M PMDPWY+ F+GTI+K   T  
Sbjct: 831  VLVNGSEGIGTGWSSSIPNYNPRDIIANVRRLLNGEMMEPMDPWYRGFRGTIEKTDPTKQ 890

Query: 2744 KDTGYTTTGVVEENEDEPNRLTITELPIRRWTQEYKEFLEAASLSGKD--KEPFIEEYMA 2917
            +  GYT  G++EE  +    L I+ELP+R+WTQ+YKEFLE+  ++G D  K+PFI++Y  
Sbjct: 891  ESVGYTVKGIIEEVNE--TTLRISELPVRKWTQDYKEFLESI-MTGNDKIKDPFIKDYKE 947

Query: 2918 HNDDTTVNFEVIMTSDQMNKARQEGXXXXXXXXXXXXXXNMHLFDSNGVIKKYDTPEQIL 3097
            HNDDTTV+FEVIM+ + +  A+QEG              NMHLFDSNG IKKY+TPEQIL
Sbjct: 948  HNDDTTVHFEVIMSEENLLMAKQEGLLQKFKLTTKISTSNMHLFDSNGTIKKYETPEQIL 1007

Query: 3098 EDFFHLRLEFYEKRKSALLHVLGRDTLQLENKVRFIGEVVEGTIIVSQRKKADLYAELKD 3277
            E+FFHLRLEFYEKRK  LL  L  + L+LENKVRFI  VV G IIVS RK+ADL+ EL  
Sbjct: 1008 EEFFHLRLEFYEKRKRVLLDNLELELLKLENKVRFILGVVRGEIIVSNRKRADLFHELHQ 1067

Query: 3278 KGYTPLPKEA-VLEASIAGAVDHVXXXXXXXXXXXXXXXXXXXXXXKPHVTASKTIPGTE 3454
            KG+TP PK++  +E ++AGA D                             +   +  T+
Sbjct: 1068 KGFTPFPKKSKSVEIAVAGATDDT-----------------EEAEENTDAVSKGGVRATD 1110

Query: 3455 YDYLLSMAISSLTYEKMKQLWDERDAKKAEFEELTHTPSRSLWLRDLDALEKQLGEQDKR 3634
            Y+YLLSMAI +LT EK+++L  +RD      ++L     ++LW+ DLDALE++L EQDK 
Sbjct: 1111 YEYLLSMAIGTLTLEKVQELCADRDKLNKGVDDLKKATPKALWITDLDALERELDEQDKN 1170

Query: 3635 DAKDEAERRKQQEKARAKGPGG---GRNARKPARKAVTKKASNTSVAAEPVETSVTSAME 3805
            DA+  AE  ++Q K+R     G    R A K  RK   KKA+N   AAE ++ S +SAME
Sbjct: 1171 DAR--AEETRKQLKSRVMSEAGMKVSRQAPKNPRKN-NKKANNAEPAAETMDVSASSAME 1227

Query: 3806 TGNAPPAVKRRGRXXXXXXXXXXXXXXXSLVDEDKDDEIPSLAERMGRQNLHSEQEDTIE 3985
              + P  VK +GR               S++ ++ DDE+  L ER+   NL S  + +  
Sbjct: 1228 MESVPEVVKPKGRAAPRKAPAKKKEMPTSVLKDEDDDEVHELKERLAAYNLESSPDGSAA 1287

Query: 3986 DIVELEDQLARHNIESSPDQEVVPXXXXXXXXXXXXXXXTITXXXXXXXXXXXXXXXXXX 4165
               E+    A    E S                        +                  
Sbjct: 1288 MEAEVPQVPAARKKEPS-------------RRAAAQKKPLASFTEISDDDEDDEDFEVEE 1334

Query: 4166 XXVLEEKKKGSGGXXXXXXXXXXXXXXXXXXXXXXXSKKSQQPAAGQKLITDVLKPAAS- 4342
                + KKKG                          + K Q    GQ L+T++ KPA + 
Sbjct: 1335 VSASDVKKKGGRKPAANAKAAAAKPAAAAAKNKRGAANKQQPQLLGQTLLTEIFKPAETL 1394

Query: 4343 GVSPEKKVRKMRPSPFNKKSGSMLGRL--------SKKNXXXXXXXXXXXXTSGEGVAAP 4498
            G+SPEKKVRKMR SPFNKKSGS+LG          +++N             S E V   
Sbjct: 1395 GISPEKKVRKMRASPFNKKSGSVLGSTGEEDETAETEENSGSASTSNSSGGESNEVVMPA 1454

Query: 4499 KARPQRANRRKTAYVL 4546
            + RPQR NR +T YV+
Sbjct: 1455 RTRPQRENRVQTRYVV 1470


>emb|CBI24922.3| unnamed protein product [Vitis vinifera]
          Length = 1452

 Score = 1721 bits (4457), Expect = 0.0
 Identities = 906/1515 (59%), Positives = 1077/1515 (71%), Gaps = 23/1515 (1%)
 Frame = +2

Query: 71   MATGQRRPLQSSTTDNIPPTTKPSTGAANKTGRTIEETYQKKTQLEHILLRPDTYIGSIE 250
            MA   + PLQSS   N+P         A   G+TIEETYQKK+QLEHILLRPDTYIGSIE
Sbjct: 1    MAVDNKLPLQSSNNANMP---------AKPAGKTIEETYQKKSQLEHILLRPDTYIGSIE 51

Query: 251  KHEQTLWVWEGDQMVKKQISYVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVEKNLI 430
            KH Q LWV+E ++MV + +SYVPGLYKIFDEILVNAADNKQRDP MDSVKV IDVEKN I
Sbjct: 52   KHTQALWVFENNEMVHRSVSYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEKNCI 111

Query: 431  SVYNNGDGIPVEIHQEEGVYVPELIFGHLLTSSNYDDSIKKTTGGRNGYGAKLANIFSTE 610
            SVYNNGDG+PVEIHQEEGVYVPE+IFGHLLTSSNYDD +KKTTGGRNGYGAKL NIFSTE
Sbjct: 112  SVYNNGDGVPVEIHQEEGVYVPEMIFGHLLTSSNYDDDVKKTTGGRNGYGAKLTNIFSTE 171

Query: 611  FIIETADGKRNRRYKQVFSNNMGKKSEPTITKCKSGENWTMVTFQPDLSKFGMECLEDDV 790
            F+IETADG+R ++YKQVFSNNMGKKSEP ITKCK  ENWT V+F+PDL+KF M  LEDDV
Sbjct: 172  FVIETADGRRQKKYKQVFSNNMGKKSEPVITKCKERENWTKVSFKPDLAKFNMTHLEDDV 231

Query: 791  VALMKKRVVDLAGCLGKTVKVELDGKRVPPKTFEDYVKLYLQSSNETF-----RLYEKVN 955
            VALMKKRVVD+AGCLGKTVKVEL+G+R+P K+F DYV LYLQS+ ++      R+ EKVN
Sbjct: 232  VALMKKRVVDIAGCLGKTVKVELNGQRIPVKSFNDYVNLYLQSAAKSRPESLPRIAEKVN 291

Query: 956  ERWEVCVSLADGHFEQVSFVNNIATIKGGTHVDYITNQIANHIVAVVKKQNKHATLKAHN 1135
            ERWE+CVSL++G F+QVSFVN+IATIKGGTHVDY+TNQIAN ++++V K+NK+A +KAH 
Sbjct: 292  ERWEICVSLSEGQFQQVSFVNSIATIKGGTHVDYVTNQIANFVMSIVNKKNKNANIKAHT 351

Query: 1136 VKNYLWVFVNALIDNPAFDSQTKETLTIKQSSFGSTCELTPEFLKKVAKSDIVKRVVSWV 1315
            VKN+LWVFVNALIDNPAFDSQTKETLTI+QSSFGS CEL+ EFLKKV+KS +V+ ++SW 
Sbjct: 352  VKNHLWVFVNALIDNPAFDSQTKETLTIRQSSFGSKCELSQEFLKKVSKSGVVESLLSWA 411

Query: 1316 QFKQQNDLKKTDGNKRGKLN-IPKLEEANYAATNNSDNCTLILTEGDSAKALAMSGLSVV 1492
             +KQ  DLKKTDG KR +L  I KLE+AN A   NS+ CTLILTEGDSAKALAM+G+SVV
Sbjct: 412  DYKQNKDLKKTDGTKRQRLTGITKLEDANDAGGRNSEKCTLILTEGDSAKALAMAGISVV 471

Query: 1493 GQDFYGVFPLRGKLLNVREASHKQLQENAEIENIKKILGLQTGKVYDNVKSLRYGHLMIM 1672
            G++ YGVFPLRGKLLNVR+A  KQ+ ENAEI+NIK+ILGLQ GK YD++KSLRYGHLMIM
Sbjct: 472  GRNHYGVFPLRGKLLNVRDAQKKQILENAEIQNIKQILGLQQGKEYDSIKSLRYGHLMIM 531

Query: 1673 ADQDHDGSHIKGLLINFLHSFWPSLLKVPNFVLEFITPIVKATNKKTKNVLSFYTMPEYE 1852
             DQDHDGSHIKGLLINF+HSFWPSLLK+P+F++EFITPIVKAT++  + VLSFY+MPEYE
Sbjct: 532  TDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHRNGR-VLSFYSMPEYE 590

Query: 1853 AWKENLGHRARDYKIKYYKGLGTSNGKEGAEYFADLEKHKKDFVWADDEDGDAIELAFSK 2032
            +WKE+LG  A  + IKYYKGLGTS  KEG EYF DL KHKKDF+W D++DGDAIELAFSK
Sbjct: 591  SWKESLGGNASGWSIKYYKGLGTSTSKEGKEYFKDLGKHKKDFMWVDEKDGDAIELAFSK 650

Query: 2033 KKIEARKNWLRALQAGTYFDSKEKHIPYRDFINKELILFSMADLQRSIPSMVDGLKPGQR 2212
            KKIE RKNWLR  Q GTY D KEK I Y DF+NKELILFSMADLQRSIPSMVDGLKPGQR
Sbjct: 651  KKIEERKNWLRQFQPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQR 710

Query: 2213 KILFCAFKKPIFQEVKVAQFSGYVSEHSAYHHGEQSLVSTIIGMAQNFVGSNNINLLYPS 2392
            KILFC+FK+   +E K+AQFSGYVSEHSAYHHGEQSL STIIGMAQ+FVGSNNINLL P+
Sbjct: 711  KILFCSFKRNFIKEAKIAQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPN 770

Query: 2393 GQFGTRQMGGKDHASGRYIYTRLSPITRHLFHKADELLLNYLNEDGQSIEPTWFIPIIPM 2572
            GQFGTR  GGKDHAS RYIYTRLSPITR LF K D++LL+YLNEDGQSIEPTW++P IPM
Sbjct: 771  GQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDILLDYLNEDGQSIEPTWYVPTIPM 830

Query: 2573 VLVNGSEGIGTGWSSFVPNYNPREIIANLKRLLNGEAMVPMDPWYKWFKGTIQK---TAA 2743
            VLVNGSEGIGTGWSS +PNYNPR+IIAN++RLLNGE M PMDPWY+ F+GTI+K   T  
Sbjct: 831  VLVNGSEGIGTGWSSSIPNYNPRDIIANVRRLLNGEMMEPMDPWYRGFRGTIEKTDPTKQ 890

Query: 2744 KDTGYTTTGVVEENEDEPNRLTITELPIRRWTQEYKEFLEAASLSGKD--KEPFIEEYMA 2917
            +  GYT  G++EE  +    L I+ELP+R+WTQ+YKEFLE+  ++G D  K+PFI++Y  
Sbjct: 891  ESVGYTVKGIIEEVNE--TTLRISELPVRKWTQDYKEFLESI-MTGNDKIKDPFIKDYKE 947

Query: 2918 HNDDTTVNFEVIMTSDQMNKARQEGXXXXXXXXXXXXXXNMHLFDSNGVIKKYDTPEQIL 3097
            HNDDTTV+FEVIM+ + +  A+QEG              NMHLFDSNG IKKY+TPEQIL
Sbjct: 948  HNDDTTVHFEVIMSEENLLMAKQEGLLQKFKLTTKISTSNMHLFDSNGTIKKYETPEQIL 1007

Query: 3098 EDFFHLRLEFYEKRKSALLHVLGRDTLQLENKVRFIGEVVEGTIIVSQRKKADLYAELKD 3277
            E+FFHLRLEFYEKRK  LL  L  + L+LENKVRFI  VV G IIVS RK+ADL+ EL  
Sbjct: 1008 EEFFHLRLEFYEKRKRVLLDNLELELLKLENKVRFILGVVRGEIIVSNRKRADLFHELHQ 1067

Query: 3278 KGYTPLPKEAVLEASIAGAVDHVXXXXXXXXXXXXXXXXXXXXXXKPHVTASKTIPGTEY 3457
            K                                                     +  T+Y
Sbjct: 1068 K-----------------------------------------------------VRATDY 1074

Query: 3458 DYLLSMAISSLTYEKMKQLWDERDAKKAEFEELTHTPSRSLWLRDLDALEKQLGEQDKRD 3637
            +YLLSMAI +LT EK+++L  +RD      ++L     ++LW+ DLDALE++L EQDK D
Sbjct: 1075 EYLLSMAIGTLTLEKVQELCADRDKLNKGVDDLKKATPKALWITDLDALERELDEQDKND 1134

Query: 3638 AKDEAERRKQQEKARAKGPGG---GRNARKPARKAVTKKASNTSVAAEPVETSVTSAMET 3808
            A+  AE  ++Q K+R     G    R A K  RK   KKA+N   AAE ++ S +SAME 
Sbjct: 1135 AR--AEETRKQLKSRVMSEAGMKVSRQAPKNPRKN-NKKANNAEPAAETMDVSASSAMEM 1191

Query: 3809 GNAPPAVKRRGRXXXXXXXXXXXXXXXSLVDEDKDDEIPSLAERMGRQNLHSEQEDTIED 3988
             + P  VK +GR               S++ ++ DDE+  L ER+   NL S  + +   
Sbjct: 1192 ESVPEVVKPKGRAAPRKAPAKKKEMPTSVLKDEDDDEVHELKERLAAYNLESSPDGSAAM 1251

Query: 3989 IVELEDQLARHNIESSPDQEVVPXXXXXXXXXXXXXXXTITXXXXXXXXXXXXXXXXXXX 4168
              E+    A    E S                        +                   
Sbjct: 1252 EAEVPQVPAARKKEPS-------------RRAAAQKKPLASFTEISDDDEDDEDFEVEEV 1298

Query: 4169 XVLEEKKKGSGGXXXXXXXXXXXXXXXXXXXXXXXSKKSQQPAAGQKLITDVLKPAAS-G 4345
               + KKKG                          + K Q    GQ L+T++ KPA + G
Sbjct: 1299 SASDVKKKGGRKPAANAKAAAAKPAAAAAKNKRGAANKQQPQLLGQTLLTEIFKPAETLG 1358

Query: 4346 VSPEKKVRKMRPSPFNKKSGSMLGRL--------SKKNXXXXXXXXXXXXTSGEGVAAPK 4501
            +SPEKKVRKMR SPFNKKSGS+LG          +++N             S E V   +
Sbjct: 1359 ISPEKKVRKMRASPFNKKSGSVLGSTGEEDETAETEENSGSASTSNSSGGESNEVVMPAR 1418

Query: 4502 ARPQRANRRKTAYVL 4546
             RPQR NR +T YV+
Sbjct: 1419 TRPQRENRVQTRYVV 1433


>ref|XP_002314046.1| predicted protein [Populus trichocarpa] gi|222850454|gb|EEE88001.1|
            predicted protein [Populus trichocarpa]
          Length = 1482

 Score = 1675 bits (4338), Expect = 0.0
 Identities = 892/1507 (59%), Positives = 1077/1507 (71%), Gaps = 25/1507 (1%)
 Frame = +2

Query: 101  SSTTDNIPPTTKPSTGAANKTGRTIEETYQKKTQLEHILLRPDTYIGSIEKHEQTLWVWE 280
            ++ T  IP +T  S     +  +TIEETYQKK+QLEHILLRPDTYIGSIEKH Q LWV+E
Sbjct: 2    AAETKKIPLSTSDSLNMNQE--KTIEETYQKKSQLEHILLRPDTYIGSIEKHAQILWVFE 59

Query: 281  GDQMVKKQISYVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVEKNLISVYNNGDGIP 460
             D+MV + ++YVPGLYKIFDEILVNAADNKQRDPKMDS+KV IDVE NL+SVYNNGDG+P
Sbjct: 60   NDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPKMDSLKVVIDVENNLVSVYNNGDGVP 119

Query: 461  VEIHQEEGVYVPELIFGHLLTSSNYDDSIKKTTGGRNGYGAKLANIFSTEFIIETADGKR 640
            V+IH+EEGVYVPELIFGHLLTSSNYDD++KKTTGGRNGYGAKL NIFSTEF+IETADGKR
Sbjct: 120  VDIHKEEGVYVPELIFGHLLTSSNYDDTMKKTTGGRNGYGAKLTNIFSTEFVIETADGKR 179

Query: 641  NRRYKQVFSNNMGKKSEPTITKCKSGENWTMVTFQPDLSKFGMECLEDDVVALMKKRVVD 820
             ++YKQVFSNNMGK+SEP ITKCK  ENWT VTF+PDL+KF M  LE+DVVALMKKRVVD
Sbjct: 180  KKKYKQVFSNNMGKRSEPIITKCKESENWTKVTFKPDLAKFSMTHLEEDVVALMKKRVVD 239

Query: 821  LAGCLGKTVKVELDGKRVPPKTFEDYVKLYLQSSNETFR-----LYEKVNERWEVCVSLA 985
            +AGCLGKTVKVEL+G RVP K+F+DYV +YL S+ E+        Y+KV ERWEVCVSL 
Sbjct: 240  MAGCLGKTVKVELNGSRVPVKSFQDYVNMYLNSAAESGSERPKCFYDKVGERWEVCVSLT 299

Query: 986  DGHFEQVSFVNNIATIKGGTHVDYITNQIANHIVAVVKKQNKHATLKAHNVKNYLWVFVN 1165
            +G F+Q SFVN+IATIKGGTHVDY+TNQI N+++  V K++K+  +KAHNVKNYLWVFVN
Sbjct: 300  EGQFQQASFVNSIATIKGGTHVDYVTNQITNYVMNAVNKKHKNGNIKAHNVKNYLWVFVN 359

Query: 1166 ALIDNPAFDSQTKETLTIKQSSFGSTCELTPEFLKKVAKSDIVKRVVSWVQFKQQNDLKK 1345
             LIDNPAFDSQTKETLT++QSSFGS CEL+ +FLKKVAKSDIV  ++SW +FK+  +LKK
Sbjct: 360  CLIDNPAFDSQTKETLTLRQSSFGSKCELSEDFLKKVAKSDIVDNLLSWAKFKENKELKK 419

Query: 1346 TDGNKRGKLNIPKLEEANYAATNNSDNCTLILTEGDSAKALAMSG---LSVVGQDFYGVF 1516
            TDG K  K+N+PKLE+AN A    S+ CTLILTEGDSAKALA++G   LS + ++FYGVF
Sbjct: 420  TDGTKTAKVNVPKLEDANEAGGRYSEKCTLILTEGDSAKALAIAGVAGLSQMERNFYGVF 479

Query: 1517 PLRGKLLNVREASHKQLQENAEIENIKKILGLQTGKVYDNVKSLRYGHLMIMADQDHDGS 1696
            PLRGKLLNVREA+ KQL+EN EIE+IKKILGLQ  K Y NVKSLRYGHLMIM DQDHDGS
Sbjct: 480  PLRGKLLNVREATSKQLKENKEIESIKKILGLQHDKQYINVKSLRYGHLMIMTDQDHDGS 539

Query: 1697 HIKGLLINFLHSFWPSLLKVPNFVLEFITPIVKATNKKTKNVLSFYTMPEYEAWKENLGH 1876
            HIKGLLINF+HSFWPSLLKVP+F++EFITPIVKAT++    VLSFY+MPEYE+WKE+L  
Sbjct: 540  HIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNG-TVLSFYSMPEYESWKESLSG 598

Query: 1877 RARDYKIKYYKGLGTSNGKEGAEYFADLEKHKKDFVWADDEDGDAIELAFSKKKIEARKN 2056
             A  + IKYYKGLGTS  KEG +YF +L KHKKDF+W D+ DGDAIELAFSKKKIEARKN
Sbjct: 599  NASGWSIKYYKGLGTSTSKEGKDYFKNLHKHKKDFLWMDELDGDAIELAFSKKKIEARKN 658

Query: 2057 WLRALQAGTYFDSKEKHIPYRDFINKELILFSMADLQRSIPSMVDGLKPGQRKILFCAFK 2236
            WLR  + GT+ D  +K I Y DFINKELILFSMADLQRSIPSMVDGLKPGQRKILFC+FK
Sbjct: 659  WLRQHEPGTHLDHNQKIIKYSDFINKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFK 718

Query: 2237 KPIFQEVKVAQFSGYVSEHSAYHHGEQSLVSTIIGMAQNFVGSNNINLLYPSGQFGTRQM 2416
            +   +E KV+QFSGYVSEHSAYHHGEQSL  TIIGMAQ+FVGSNNINLL P+GQFGTR +
Sbjct: 719  RNFVKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDFVGSNNINLLQPNGQFGTRSV 778

Query: 2417 GGKDHASGRYIYTRLSPITRHLFHKADELLLNYLNEDGQSIEPTWFIPIIPMVLVNGSEG 2596
            GGKDHAS RYIYT+LSPITR LF K D+ LL+YL+EDGQ+IEPTW++PIIP VLVNG EG
Sbjct: 779  GGKDHASARYIYTQLSPITRFLFPKDDDGLLDYLDEDGQTIEPTWYMPIIPTVLVNGCEG 838

Query: 2597 IGTGWSSFVPNYNPREIIANLKRLLNGEAMVPMDPWYKWFKGTIQKTAAKDTG---YTTT 2767
            IGTGWS+F+PNYNPR+++AN++RLLNGE M PM+PWY+ FKGTI+K A+K+ G   YT  
Sbjct: 839  IGTGWSTFIPNYNPRDVVANIRRLLNGEMMEPMNPWYRGFKGTIEKGASKEGGCSSYTVN 898

Query: 2768 GVVEENEDEPNRLTITELPIRRWTQEYKEFLEAASLSGKD------KEPFIEEYMAHNDD 2929
            GV+  NE     L ITELPIRRWT +YK FL + +   +D      K+PF++++  + DD
Sbjct: 899  GVI--NEVNETTLRITELPIRRWTDDYKAFLNSVTEGTRDENGNLPKDPFVKDFRKYGDD 956

Query: 2930 TTVNFEVIMTSDQMNKARQEGXXXXXXXXXXXXXXNMHLFDSNGVIKKYDTPEQILEDFF 3109
              V+FEV ++ + M  A+QEG              NMHLFDS GVIKKYD PEQILE+FF
Sbjct: 957  AAVHFEVQLSEENMLVAKQEGLLKKFKLTTTISTSNMHLFDSAGVIKKYDNPEQILENFF 1016

Query: 3110 HLRLEFYEKRKSALLHVLGRDTLQLENKVRFIGEVVEGTIIVSQRKKADLYAELKDKGYT 3289
            HLRLE+YE RK  LL  L  + L+LENKVRFI  VV G IIV+ RK+ADL  EL  KG+ 
Sbjct: 1017 HLRLEYYETRKKVLLENLEFELLKLENKVRFILGVVRGEIIVNNRKRADLLLELHQKGFN 1076

Query: 3290 PLPKEAVLEASIAGAVDHVXXXXXXXXXXXXXXXXXXXXXXKPHVTASKTIPGTEYDYLL 3469
            P+PK++  +A +AGA D                         P V+    +  ++YDYLL
Sbjct: 1077 PIPKKS--KAVVAGATDDT-----------------EEAEDSPDVSG---VRASDYDYLL 1114

Query: 3470 SMAISSLTYEKMKQLWDERDAKKAEFEELTHTPSRSLWLRDLDALEKQLGEQDKRDAKDE 3649
            SMAI +LT E+++QL  +RD    E + L  T  + LW++DL+ALE QL   D+ DA+ E
Sbjct: 1115 SMAIGTLTLERVQQLCADRDKLNGEVDSLRKTTPKVLWVKDLEALEMQLDMLDEYDAEAE 1174

Query: 3650 AERRKQQEKARAKGPGG---GRNARKPARKAVTKKASNTSVAAEPVETSVTSAMETG--- 3811
              RRK  +   AKG  G    + A K  RK  TKKA N  V+ E   TS + A+ET    
Sbjct: 1175 EARRK-LKGGGAKGEAGFKVSKQAPKYPRKN-TKKAINEEVSVETTGTSSSFAIETASSE 1232

Query: 3812 NAPPAVKRRGRXXXXXXXXXXXXXXXSLVDEDKDDEIPSLAERMGRQNLHSEQEDTIEDI 3991
            NA   VK +GR                L D D+DDEI SL +R+    L S  E + +  
Sbjct: 1233 NAAAVVKPKGRAGSKKAPAKMEKLSPVLDDFDEDDEIESLKDRLNAYRLDSSPEQSADME 1292

Query: 3992 VELEDQLARHNIESSPDQEVVPXXXXXXXXXXXXXXXTITXXXXXXXXXXXXXXXXXXXX 4171
             ++    AR                             ++                    
Sbjct: 1293 TDVLQVPARRGAARK------------------KPLANVSVISDSEDEPNLDDDADVEVK 1334

Query: 4172 VLEEKKKGSGGXXXXXXXXXXXXXXXXXXXXXXXSKKSQQPAAGQKLITDVLKPA-ASGV 4348
             L E KK  GG                       S++SQ    GQKL+T++LKPA  +G+
Sbjct: 1335 ALPETKK-KGGRKAAAANDKAAKPPAATKRRGPASQQSQ--GLGQKLLTEMLKPAEGAGI 1391

Query: 4349 SPEKKVRKMRPSPFNKKSGSMLGRLSKKNXXXXXXXXXXXXTSGEGVAAP-KARPQRANR 4525
            SPEKKVRK+R SPFNKKSGS+LGR+ K++             + + +  P +ARPQRANR
Sbjct: 1392 SPEKKVRKVRASPFNKKSGSVLGRIHKEDDTGSEPMSASSSENTDVIDVPARARPQRANR 1451

Query: 4526 RKTAYVL 4546
            ++T YVL
Sbjct: 1452 KQTRYVL 1458


>gb|AAN85207.1| DNA topoisomerase II [Nicotiana tabacum] gi|26984168|gb|AAN85208.1|
            DNA topoisomerase II [Nicotiana tabacum]
          Length = 1482

 Score = 1640 bits (4246), Expect = 0.0
 Identities = 828/1311 (63%), Positives = 1009/1311 (76%), Gaps = 10/1311 (0%)
 Frame = +2

Query: 83   QRRPLQSSTTDNIPPTTKPSTGAANKTGRTIEETYQKKTQLEHILLRPDTYIGSIEKHEQ 262
            ++ PLQSS+  NI         A N  G+TIE+TYQKKTQLEHILLRPDTYIGS+EKH Q
Sbjct: 4    KKLPLQSSSNANI---------ATN--GKTIEQTYQKKTQLEHILLRPDTYIGSVEKHTQ 52

Query: 263  TLWVWEGDQMVKKQISYVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVEKNLISVYN 442
            TLWVWE D+M  + ++YVPGLYKIFDEILVNAADNKQRDPKMD+V+V ID E+N ISVYN
Sbjct: 53   TLWVWENDKMTHRPVTYVPGLYKIFDEILVNAADNKQRDPKMDAVEVVIDPEQNFISVYN 112

Query: 443  NGDGIPVEIHQEEGVYVPELIFGHLLTSSNYDDSIKKTTGGRNGYGAKLANIFSTEFIIE 622
            NGDGIPVEIHQEEGVYVPELIFGHLLTSSNYDD+ KKTTGGRNGYGAKL NIFSTEF+IE
Sbjct: 113  NGDGIPVEIHQEEGVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIE 172

Query: 623  TADGKRNRRYKQVFSNNMGKKSEPTITKCKSGENWTMVTFQPDLSKFGMECLEDDVVALM 802
            TADGKR ++YKQVFS+NMGKK EP ITKCK+ ENWT V+ +PDL+KF ME LE+DVVALM
Sbjct: 173  TADGKRQKKYKQVFSSNMGKKGEPIITKCKASENWTKVSSKPDLAKFNMEHLEEDVVALM 232

Query: 803  KKRVVDLAGCLGKTVKVELDGKRVPPKTFEDYVKLYLQSSNETFRLYEKVNE-----RWE 967
            +KRV+DL GCLGKTVKV+L+ +R+P K+FE+Y KL+L S++   R + KV +     RWE
Sbjct: 233  RKRVIDLGGCLGKTVKVKLNEQRIPVKSFEEYCKLFLDSTDAK-REFLKVTDADGLLRWE 291

Query: 968  VCVSLADGHFEQVSFVNNIATIKGGTHVDYITNQIANHIVAVVKKQNKHATLKAHNVKNY 1147
            +CVSL++G F+QVSFVN+IATIKGGTHVDY+ NQIANHI+  V K+NK+A +KAH VKN+
Sbjct: 292  ICVSLSEGQFQQVSFVNSIATIKGGTHVDYVANQIANHIMGAVIKKNKNANIKAHAVKNH 351

Query: 1148 LWVFVNALIDNPAFDSQTKETLTIKQSSFGSTCELTPEFLKKVAKS-DIVKRVVSWVQFK 1324
            LW+FVNALIDNPAFDSQTKETLT++QSSFGS CEL P+FLKKV K+  IV+ ++SW  FK
Sbjct: 352  LWMFVNALIDNPAFDSQTKETLTLRQSSFGSKCELQPDFLKKVEKNIGIVETLLSWADFK 411

Query: 1325 QQNDLKKTDGNKRGKLNIPKLEEANYAATNNSDNCTLILTEGDSAKALAMSGLSVVGQDF 1504
               DLKKTDG K  K+ + KLE+AN A   NS+ CTLILTEGDSAKALAM+G+SVVG+D 
Sbjct: 412  NSKDLKKTDGKKSEKVKVEKLEDANDAGGRNSEKCTLILTEGDSAKALAMAGISVVGRDH 471

Query: 1505 YGVFPLRGKLLNVREASHKQLQENAEIENIKKILGLQTGKVYDNVKSLRYGHLMIMADQD 1684
            YGVFPLRGKLLNVREASHKQ+ EN EIE IKKILGLQTGK YD+VKSLRYGHLMIM DQD
Sbjct: 472  YGVFPLRGKLLNVREASHKQVSENKEIEAIKKILGLQTGKEYDSVKSLRYGHLMIMTDQD 531

Query: 1685 HDGSHIKGLLINFLHSFWPSLLKVPNFVLEFITPIVKATNKKTKNVLSFYTMPEYEAWKE 1864
            HDGSHIKGLLINF+H+FWPSLLKVP+F++EFITPIVKAT+K  K +LSFYTMPEYE+W++
Sbjct: 532  HDGSHIKGLLINFIHTFWPSLLKVPSFLIEFITPIVKATHKSGK-ILSFYTMPEYESWRK 590

Query: 1865 NLGHRARDYKIKYYKGLGTSNGKEGAEYFADLEKHKKDFVWADDEDGDAIELAFSKKKIE 2044
            +LG  +  + IKYYKGLGTS  KEG EYF DL+KH+KDF+WAD++DG++IELAFSKKKIE
Sbjct: 591  SLGANSSGWSIKYYKGLGTSTSKEGKEYFQDLQKHRKDFIWADNQDGESIELAFSKKKIE 650

Query: 2045 ARKNWLRALQAGTYFDSKEKHIPYRDFINKELILFSMADLQRSIPSMVDGLKPGQRKILF 2224
            ARKNWLR  + GT+ D KEK+I Y +F+NKELILFSMADLQRSIPSM+DGLKPGQRKILF
Sbjct: 651  ARKNWLRQFEPGTHLDQKEKYISYTEFVNKELILFSMADLQRSIPSMLDGLKPGQRKILF 710

Query: 2225 CAFKKPIFQEVKVAQFSGYVSEHSAYHHGEQSLVSTIIGMAQNFVGSNNINLLYPSGQFG 2404
            CAFK+   +E KV+QFSGYVSEHSAYHHGEQSL STIIGMAQ++VGSNN+NLL P+GQFG
Sbjct: 711  CAFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLSSTIIGMAQDYVGSNNVNLLQPNGQFG 770

Query: 2405 TRQMGGKDHASGRYIYTRLSPITRHLFHKADELLLNYLNEDGQSIEPTWFIPIIPMVLVN 2584
            TR MGGKDHAS RYIYTRLSPI R LF K D+ + +YLNEDGQ IEPTW++PI+PMVL+N
Sbjct: 771  TRNMGGKDHASSRYIYTRLSPIARFLFPKEDDTIHDYLNEDGQYIEPTWYVPIVPMVLIN 830

Query: 2585 GSEGIGTGWSSFVPNYNPREIIANLKRLLNGEAMVPMDPWYKWFKGTIQKTAAKDTG--Y 2758
            GSEGIGTGWSS+VPNYNPR+++AN++RLLN E M PMDPWYK FKGTI+KTA K+ G  Y
Sbjct: 831  GSEGIGTGWSSYVPNYNPRDLVANVRRLLNDEPMEPMDPWYKGFKGTIEKTATKEAGATY 890

Query: 2759 TTTGVVEENEDEPNRLTITELPIRRWTQEYKEFLEAASLSG-KDKEPFIEEYMAHNDDTT 2935
            T TG++EE  +    L I+ELP+RRWT++YK+FLE+ ++S  K K+PFI+E  A+ D+ +
Sbjct: 891  TVTGIIEEVNE--TTLRISELPVRRWTEDYKQFLESMTVSNDKAKDPFIKEVRAYGDENS 948

Query: 2936 VNFEVIMTSDQMNKARQEGXXXXXXXXXXXXXXNMHLFDSNGVIKKYDTPEQILEDFFHL 3115
            V FEVIM+ + +  A+QEG              NMHLFDSNG IKKYD PE ILE+F+H+
Sbjct: 949  VCFEVIMSEENLILAQQEGLLKKFKLATTISTSNMHLFDSNGKIKKYDNPEDILEEFYHV 1008

Query: 3116 RLEFYEKRKSALLHVLGRDTLQLENKVRFIGEVVEGTIIVSQRKKADLYAELKDKGYTPL 3295
            RLE+YEKRK ALL +L  + L++ENKV+FI  VV+  IIV+ RK+ADL  ELK+KG+TP 
Sbjct: 1009 RLEYYEKRKKALLEILELELLRIENKVKFILGVVKVEIIVNNRKRADLLLELKEKGFTPF 1068

Query: 3296 PKEAVLEASIAGAVDHVXXXXXXXXXXXXXXXXXXXXXXKPHVTASKTIPGTEYDYLLSM 3475
            PK+  +EA +A   D                              ++ +   +YDYLLSM
Sbjct: 1069 PKKKAVEAVVADTSDDA---------------------EDSEEELNRGVRAGDYDYLLSM 1107

Query: 3476 AISSLTYEKMKQLWDERDAKKAEFEELTHTPSRSLWLRDLDALEKQLGEQDKRDAKDEAE 3655
             I +LT EK+++L  ERD    E E++ +   + LWL+DLD LEKQL EQDK D + E  
Sbjct: 1108 PIGTLTLEKVQELCAERDQLNGEVEDMRNATPKLLWLKDLDVLEKQLDEQDKIDIQAEEA 1167

Query: 3656 RRKQQEKARAKGPGGGRNARKPARKAVTKKASNTSVAAEPVE-TSVTSAMETGNAPPAVK 3832
            R K ++K        G  A KP  +   KKAS     AEP++  S  ++    N    VK
Sbjct: 1168 REKIKKKVM---NAAGLKAPKPKPRKNVKKASVVESTAEPMDRVSCFNSGNRSNVTEVVK 1224

Query: 3833 RRGRXXXXXXXXXXXXXXXSLVDEDKDDEIPSLAERMGRQNLHSEQEDTIE 3985
             + R                  +E++DDE+ +L +R+   NL+S  + + E
Sbjct: 1225 PKARGGSKKAPAKAKPIAVEDEEEEEDDEVLALKDRLAAYNLNSSPDHSAE 1275



 Score = 64.7 bits (156), Expect = 2e-07
 Identities = 42/95 (44%), Positives = 52/95 (54%), Gaps = 8/95 (8%)
 Frame = +2

Query: 4286 QQPAAGQKLITDVLKPAAS--GVSPEKKVRKMRPSPFNKKSGSMLGR------LSKKNXX 4441
            Q    GQKLIT +LKPA +    SPEKKVRKMR SPFN+KSG++LG+         ++  
Sbjct: 1360 QAVGIGQKLITSILKPAENTDNSSPEKKVRKMRASPFNEKSGAVLGKNKGSTLQENEDAS 1419

Query: 4442 XXXXXXXXXXTSGEGVAAPKARPQRANRRKTAYVL 4546
                         E V APKAR  R   +KT YV+
Sbjct: 1420 PVSSLGSLEDEVNEAVVAPKARVTRG--KKTTYVI 1452


>dbj|BAE06274.1| topoisomerase II [Scutellaria baicalensis]
          Length = 1469

 Score = 1614 bits (4179), Expect = 0.0
 Identities = 869/1512 (57%), Positives = 1049/1512 (69%), Gaps = 20/1512 (1%)
 Frame = +2

Query: 71   MATGQRRPLQSSTTDNIPPTTKPSTGAANKTGRTIEETYQKKTQLEHILLRPDTYIGSIE 250
            MA G++ PL +S   NIPP      G+     +TIE+ YQKKTQLEHILLRPDTYIGSIE
Sbjct: 1    MAGGKKGPLTTSNNANIPPPDAAGGGSK----KTIEQAYQKKTQLEHILLRPDTYIGSIE 56

Query: 251  KHEQTLWVWEGDQMVKKQISYVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVEKNLI 430
            +H QTLWV+E +QMV+K I+YVPGLYKIFDEILVNAADNKQRDPKM+SVKVTIDVE N I
Sbjct: 57   RHTQTLWVYENEQMVQKSITYVPGLYKIFDEILVNAADNKQRDPKMNSVKVTIDVESNCI 116

Query: 431  SVYNNGDGIPVEIHQEEGVYVPELIFGHLLTSSNYDDSIKKTTGGRNGYGAKLANIFSTE 610
            SVYNNGDG+PVEIHQEEGVYVPELIFGHLLTSSNYDD+ KKTTGGRNGYGAKL NIFSTE
Sbjct: 117  SVYNNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTE 176

Query: 611  FIIETADGKRNRRYKQVFSNNMGKKSEPTITKCKSGENWTMVTFQPDLSKFGMECLEDDV 790
            F+IETADGKR ++YKQVFSNNMG KSEP I+K ++G++WT +TF+PDL+KF M CLEDD 
Sbjct: 177  FVIETADGKREKKYKQVFSNNMGTKSEPIISKRQAGDDWTKITFKPDLAKFNMTCLEDDT 236

Query: 791  VALMKKRVVDLAGCLGKTVKVELDGKRVPPKTFEDYVKLYLQSSNETF-----RLYEKVN 955
            VALMKKRV+D+AGCLGKTVKVEL+G++   K+F  Y  LY++S++ +      R  E+V+
Sbjct: 237  VALMKKRVIDIAGCLGKTVKVELNGQKFHFKSFSSYCDLYMKSTSVSSLDPLPRFEEEVH 296

Query: 956  ERWEVCVSLADGHFEQVSFVNNIATIKGGTHVDYITNQIANHIVAVVK---KQNKHATLK 1126
            ERW++ VS ++G F+QVSFVN IATIKGGTHVDY+TN+I +H+V V+K   K+NK   LK
Sbjct: 297  ERWQIFVSRSEGQFQQVSFVNGIATIKGGTHVDYVTNKITSHLVNVIKNKNKKNKKFDLK 356

Query: 1127 AHNVKNYLWVFVNALIDNPAFDSQTKETLTIKQSSFGSTCELTPEFLKKVAKSDIVKRVV 1306
             H VKN+LWVFVNALIDNPAFDSQTKETLT++ +SFGS+ + +  FL +VAKSDI+K + 
Sbjct: 357  PHTVKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSNFLDRVAKSDIMKNIE 416

Query: 1307 SWVQFKQQNDLKKTDGNKRGKL-NIPKLEEANYAATNNSDNCTLILTEGDSAKALAMSGL 1483
             W +FKQ+ DLKKTDG+K  ++  + KL +AN A   NSD CTLILTEGDSAKALA++GL
Sbjct: 417  EWAEFKQKKDLKKTDGSKDRRIYGLAKLSDANEAGGRNSDKCTLILTEGDSAKALAIAGL 476

Query: 1484 SVVGQDFYGVFPLRGKLLNVREASHKQLQENAEIENIKKILGLQTGKVYDNVKSLRYGHL 1663
            SVVG+D YGVFPLRGKLLNVREASH QL  N EI++IK+ILGLQ GK Y++VK LRYGHL
Sbjct: 477  SVVGRDHYGVFPLRGKLLNVREASHNQLMHNLEIQHIKQILGLQHGKQYESVKPLRYGHL 536

Query: 1664 MIMADQDHDGSHIKGLLINFLHSFWPSLLKVPNFVLEFITPIVKATNKKTKNVLSFYTMP 1843
            MIM DQDHDGSHIKGLLINF+HSFWPSLLK+P+F+L FITPIVKA +K  K  LSFYTMP
Sbjct: 537  MIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLLGFITPIVKARHKDGKRKLSFYTMP 596

Query: 1844 EYEAWKENLGHRARDYKIKYYKGLGTSNGKEGAEYFADLEKHKKDFVWADDEDGDAIELA 2023
            +YEAWKE  G  A+++ +KYYKGLGTS  +E  EYF+DL KH+KDFV+ D ED DAIELA
Sbjct: 597  QYEAWKEAQGTEAKNWTVKYYKGLGTSTDQEAMEYFSDLGKHEKDFVYVDGEDDDAIELA 656

Query: 2024 FSKKKIEARKNWLRALQAGTYFDSKEKHIPYRDFINKELILFSMADLQRSIPSMVDGLKP 2203
            FSKKKIEARK WLR  + GT+ D ++ HI YRDF++KELILFS+AD+QRSIPSMVDGLKP
Sbjct: 657  FSKKKIEARKGWLRQFEPGTFLDDRDSHIKYRDFVHKELILFSIADVQRSIPSMVDGLKP 716

Query: 2204 GQRKILFCAFKKPIFQEVKVAQFSGYVSEHSAYHHGEQSLVSTIIGMAQNFVGSNNINLL 2383
            GQRKILFC+FK+   +E KVAQFSGYVSEHSAYHHGEQSL  TIIGMAQ++VGSNNINLL
Sbjct: 717  GQRKILFCSFKRNFVREAKVAQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLL 776

Query: 2384 YPSGQFGTRQMGGKDHASGRYIYTRLSPITRHLFHKADELLLNYLNEDGQSIEPTWFIPI 2563
             P GQFGTR  GGKDHAS RY++T+LSP+TR LF KAD++LL+YLNEDGQSIEPTW++PI
Sbjct: 777  LPIGQFGTRGQGGKDHASARYVFTQLSPVTRFLFPKADDILLDYLNEDGQSIEPTWYVPI 836

Query: 2564 IPMVLVNGSEGIGTGWSSFVPNYNPREIIANLKRLLNGEAMVPMDPWYKWFKGTIQKTAA 2743
            IPMVLVNGSEGIGTGWSS+VPNYNP +IIAN++ LLN EA  PM PWYK F G+++KTA 
Sbjct: 837  IPMVLVNGSEGIGTGWSSYVPNYNPVDIIANIRHLLNDEATEPMHPWYKGFLGSVEKTAT 896

Query: 2744 KDTG--YTTTGVVEENEDEPNRLTITELPIRRWTQEYKEFLEAASL-SGKDKEPFIEEYM 2914
            K+ G  YT +G++EE +D    L I ELPIRRWTQ+YKEFLE+ S  + K K+PFIE   
Sbjct: 897  KEAGASYTVSGIIEEVDD--TTLCIKELPIRRWTQDYKEFLESVSAENDKSKDPFIEGCR 954

Query: 2915 AHNDDTTVNFEVIMTSDQMNKARQEGXXXXXXXXXXXXXXNMHLFDSNGVIKKYDTPEQI 3094
             ++    VNF V M  +++  A++EG              NMHLFDS GVIKKYDTPEQI
Sbjct: 955  DYSGSELVNFLVGMKPEKLEAAKREGLLKKFKLTTSISTCNMHLFDSKGVIKKYDTPEQI 1014

Query: 3095 LEDFFHLRLEFYEKRKSALLHVLGRDTLQLENKVRFIGEVVEGTIIVSQRKKADLYAELK 3274
            LE+FF++RLE YEKRK  LL +L  D L+ +NK RFI  VVEG+IIVS RK+ D++ ELK
Sbjct: 1015 LEEFFYIRLELYEKRKKVLLDILEHDMLKCDNKYRFIRCVVEGSIIVSNRKRTDVFRELK 1074

Query: 3275 DKGYTPLPKEA-VLEASIAGAVDHVXXXXXXXXXXXXXXXXXXXXXXKPHVTASKTIPGT 3451
            +KG+TP PK+    E +IAGA D                           V  +  +  +
Sbjct: 1075 EKGFTPFPKKKNRAEVAIAGATD-----------------DGEETEENSEVPIAPGVSSS 1117

Query: 3452 EYDYLLSMAISSLTYEKMKQLWDERDAKKAEFEELTHTPSRSLWLRDLDALEKQLGEQDK 3631
            +YDYLLS+AI +LT EKM++L  ERD    E EEL  + +RSLW +DLDALE +L E+ K
Sbjct: 1118 DYDYLLSLAIGTLTTEKMQELRAERDKLMQEVEELKQSTARSLWNKDLDALEDKLAEEQK 1177

Query: 3632 -RDAKDEAERRKQQEKARAKGPGGGRNARKPARKAVTKKASNTSVAAEPVETSVTSAMET 3808
              +   E  +RK   K         +N RK   K  TKK S        VE  ++    T
Sbjct: 1178 IYEETWEKNKRKIHGKTDTL-EIIQKNPRK--NKKTTKKES-------AVEMEISENTTT 1227

Query: 3809 GNAPPAVKRRGRXXXXXXXXXXXXXXXSLVDEDKDDEIPSLAERMGRQNLHSEQEDTIED 3988
                   K RG+               + V+E +DD                      + 
Sbjct: 1228 ETDVKIKKPRGKAAAKKKEPAAKVVTAAPVEEQEDD----------------------DG 1265

Query: 3989 IVELEDQLARHNIESSPDQ------EVVPXXXXXXXXXXXXXXXTITXXXXXXXXXXXXX 4150
            I +L  ++A +N +SSPD       EV P                 T             
Sbjct: 1266 IADLRQRIAAYNFDSSPDHSEDMATEVAPVQTKNKQPARRGAAQKKTLSAASETDEDDDA 1325

Query: 4151 XXXXXXXVLEEKKKGSGGXXXXXXXXXXXXXXXXXXXXXXXSKKSQQPAAGQKLITDVLK 4330
                     EEKKK  G                        S K      GQKLIT+VLK
Sbjct: 1326 FEP------EEKKKKGG-------RKPAAAKAPAAAKKRGPSAKQSSQLVGQKLITEVLK 1372

Query: 4331 PAASGVSPEKKVRKMRPSPFNKKSGSMLGRLSKKNXXXXXXXXXXXXTSGEGVAAPKARP 4510
            PAA   SPEKKVR+MR SPFNKKS S+LG   K              TS     A  ARP
Sbjct: 1373 PAADD-SPEKKVRRMRESPFNKKSSSILG---KTINIDDDDEEETSGTSSMNEGAAAARP 1428

Query: 4511 QRANRRKTAYVL 4546
            +RANR K  YV+
Sbjct: 1429 KRANRGKAKYVI 1440