BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Atractylodes21_contig00003383
         (2007 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gb|ACF17660.1| putative isopropylmalate synthase [Capsicum annuum]    914   0.0  
sp|O04973.1|LEU1A_SOLPN RecName: Full=2-isopropylmalate synthase...   892   0.0  
sp|O04974.1|LEU1B_SOLPN RecName: Full=2-isopropylmalate synthase...   887   0.0  
ref|XP_002268942.2| PREDICTED: 2-isopropylmalate synthase 2, chl...   875   0.0  
ref|XP_002530549.1| isopropylmalate synthase, putative [Ricinus ...   868   0.0  

>gb|ACF17660.1| putative isopropylmalate synthase [Capsicum annuum]
          Length = 602

 Score =  914 bits (2361), Expect = 0.0
 Identities = 465/571 (81%), Positives = 519/571 (90%), Gaps = 6/571 (1%)
 Frame = +1

Query: 292  RALLHFKPSRIPSRKLFSIV---CS--SRPEYIPNHIPDPNYVRIFDTTLRDGEQSPGAT 456
            + LL+FKPS IP+   FSI    CS   RPEY P+HI DPNY+RIFDTTLRDGEQSPGAT
Sbjct: 21   QTLLNFKPS-IPTHS-FSIPIVRCSIRCRPEYTPSHISDPNYIRIFDTTLRDGEQSPGAT 78

Query: 457  MTTKEKLDIARQLAKLGVDIIEAGFPASSQADLEAVKLIAQEVGNMGAGEDGHVPVICGL 636
            MTTKEKLD+ARQLAKLGVDIIEAGFPASS+ADLEAVKLIA+EVGN G  E+GHVPVICGL
Sbjct: 79   MTTKEKLDVARQLAKLGVDIIEAGFPASSEADLEAVKLIAKEVGN-GVYEEGHVPVICGL 137

Query: 637  SRCNKNDIDKAWEAVKHAKFPRIHTFIATSEIHMQYKLNMSKEQVIEKARSMVAYARSLG 816
            +RCNK DIDKAWEAVK+AK PRIHTFIATSEIHM++KL MS+++VIEKARSMVAYARS+G
Sbjct: 138  ARCNKRDIDKAWEAVKYAKKPRIHTFIATSEIHMKFKLKMSRDEVIEKARSMVAYARSIG 197

Query: 817  CNDVEFSPEDAGRSEREFLYEILGEVIKAGATTLNIPDTVGYNWPREFGQLIADIRANTP 996
            C DVEFSPEDAGRS+ EFLY ILGEVIKAGATTLNIPDTVGY  P EFGQLIA+I+ANTP
Sbjct: 198  CQDVEFSPEDAGRSDPEFLYHILGEVIKAGATTLNIPDTVGYTVPEEFGQLIANIKANTP 257

Query: 997  GIENVIISTHCQNDLGLSTANTLEGAYSGARQLEVTINGIGERAGNASLEEVVMTIKCKG 1176
            G+E+VIISTHCQNDLGLSTANTL GA +GARQLEVTINGIGERAGNASLEEVVM +KC+G
Sbjct: 258  GVEDVIISTHCQNDLGLSTANTLAGACAGARQLEVTINGIGERAGNASLEEVVMALKCRG 317

Query: 1177 E-VLGGLYTGINTRHIVMASKMVEEYSGLLVQPHKAIVGANAFAHESGIHQDGMLKNKST 1353
            E VLGGLYTGINT+HI+M+SKMVEEY+GL VQPHKAIVGANAFAHESGIHQDGMLK+K T
Sbjct: 318  EQVLGGLYTGINTQHILMSSKMVEEYTGLHVQPHKAIVGANAFAHESGIHQDGMLKHKDT 377

Query: 1354 YEIMSPEDIGLFRSNESGLTLGKLSGRHALKSKLFELGYDIDGKELNDLFWRFKSVAEMK 1533
            YEIMSPEDIGL R+NESG+ LGKLSGRHAL++K+ ELGY+I+GKEL+DLFWRFKSVAE K
Sbjct: 378  YEIMSPEDIGLNRANESGIVLGKLSGRHALQAKMLELGYEIEGKELDDLFWRFKSVAEKK 437

Query: 1534 KVITDDDLVALVSDEVFQPQVVWKFGDVQVTCGTLGLSTATVKLIDSDGKEHIACSTGTG 1713
            K ITDDDL+AL+SDEVFQPQ VW+  +VQVTCG+LGLSTATVKLID+DGKEHI+CS GTG
Sbjct: 438  KKITDDDLIALMSDEVFQPQFVWQLQNVQVTCGSLGLSTATVKLIDADGKEHISCSVGTG 497

Query: 1714 PVDAAYKAVDLIVKVPVKLLEYSMSAVTAGIDALASTRVLISGENTHIATHASTGEKIVR 1893
            PVDAAYKAVDLIVK+PV LLEYSM+AVT GIDA+ASTRVLI GEN H +THA TGE + R
Sbjct: 498  PVDAAYKAVDLIVKIPVTLLEYSMNAVTQGIDAIASTRVLIRGENGHTSTHALTGETVHR 557

Query: 1894 TYSGTGASMDIVISSVRAYVGALNKMLGLKK 1986
            T+SGTGA MDIVISSVRAY+GALNKM+  +K
Sbjct: 558  TFSGTGADMDIVISSVRAYIGALNKMMSFRK 588


>sp|O04973.1|LEU1A_SOLPN RecName: Full=2-isopropylmalate synthase A; AltName: Full=Alpha-IPM
            synthase A; AltName: Full=Alpha-isopropylmalate synthase
            A gi|2213882|gb|AAB61598.1| 2-isopropylmalate synthase
            [Solanum pennellii]
          Length = 589

 Score =  892 bits (2304), Expect = 0.0
 Identities = 446/547 (81%), Positives = 494/547 (90%), Gaps = 1/547 (0%)
 Frame = +1

Query: 349  VCSSRPEYIPNHIPDPNYVRIFDTTLRDGEQSPGATMTTKEKLDIARQLAKLGVDIIEAG 528
            + + RPEY+P+ I DP YVRIFDTTLRDGEQSPGATMTTKEKLD+ARQLAKLGVDIIEAG
Sbjct: 30   ISNRRPEYVPSKISDPKYVRIFDTTLRDGEQSPGATMTTKEKLDVARQLAKLGVDIIEAG 89

Query: 529  FPASSQADLEAVKLIAQEVGNMGAGEDGHVPVICGLSRCNKNDIDKAWEAVKHAKFPRIH 708
            FPASS+AD E+VKLIA+E+GN    E+G VPVICGLSRCNK+DIDKAWEAVK+AK PR+H
Sbjct: 90   FPASSEADFESVKLIAEEIGN-NTDENGFVPVICGLSRCNKSDIDKAWEAVKYAKKPRVH 148

Query: 709  TFIATSEIHMQYKLNMSKEQVIEKARSMVAYARSLGCNDVEFSPEDAGRSEREFLYEILG 888
            TFIATSEIHM+YKL MS+EQV+EKARSMVAYARSLGC DVEFSPEDAGRS+REFLY+ILG
Sbjct: 149  TFIATSEIHMKYKLKMSREQVVEKARSMVAYARSLGCEDVEFSPEDAGRSDREFLYDILG 208

Query: 889  EVIKAGATTLNIPDTVGYNWPREFGQLIADIRANTPGIENVIISTHCQNDLGLSTANTLE 1068
            EVIKAGATTLNIPDTVGY  P EFGQLI DI+ANTPGIENVIISTHCQNDLGLSTANTL 
Sbjct: 209  EVIKAGATTLNIPDTVGYTVPSEFGQLITDIKANTPGIENVIISTHCQNDLGLSTANTLA 268

Query: 1069 GAYSGARQLEVTINGIGERAGNASLEEVVMTIKCKGE-VLGGLYTGINTRHIVMASKMVE 1245
            GA +GARQLEVTINGIGERAGNASLEEVVM +KC+GE VLGGLYTGINT+HIV +SKMVE
Sbjct: 269  GACAGARQLEVTINGIGERAGNASLEEVVMALKCRGEQVLGGLYTGINTQHIVPSSKMVE 328

Query: 1246 EYSGLLVQPHKAIVGANAFAHESGIHQDGMLKNKSTYEIMSPEDIGLFRSNESGLTLGKL 1425
            EYSGL VQPHKAIVGANAFAHESGIHQDGMLK+K TYEI+SP+D+GL RSNE+G+ LGKL
Sbjct: 329  EYSGLQVQPHKAIVGANAFAHESGIHQDGMLKHKDTYEIISPDDVGLSRSNEAGIVLGKL 388

Query: 1426 SGRHALKSKLFELGYDIDGKELNDLFWRFKSVAEMKKVITDDDLVALVSDEVFQPQVVWK 1605
            SGRHALKSK+ ELGYDIDGKEL DLFWRFKSVAE KK ITDDDL+AL+SDEV QP V WK
Sbjct: 389  SGRHALKSKMLELGYDIDGKELEDLFWRFKSVAEKKKKITDDDLIALMSDEVLQPNVYWK 448

Query: 1606 FGDVQVTCGTLGLSTATVKLIDSDGKEHIACSTGTGPVDAAYKAVDLIVKVPVKLLEYSM 1785
             GDVQ+ CG+LGLSTATVKLI++DG+EHIACS GTGPVDAAYKAVDLIVKVP+ LLEYSM
Sbjct: 449  LGDVQIMCGSLGLSTATVKLINTDGQEHIACSVGTGPVDAAYKAVDLIVKVPITLLEYSM 508

Query: 1786 SAVTAGIDALASTRVLISGENTHIATHASTGEKIVRTYSGTGASMDIVISSVRAYVGALN 1965
            +AVT GIDA+ASTRV I   + H   + STG+ I RT+SGTGA MD+VISSVRAY+GALN
Sbjct: 509  NAVTEGIDAIASTRVSICSIDRHTIMNGSTGQTIHRTFSGTGADMDVVISSVRAYIGALN 568

Query: 1966 KMLGLKK 1986
            KML  +K
Sbjct: 569  KMLSYEK 575


>sp|O04974.1|LEU1B_SOLPN RecName: Full=2-isopropylmalate synthase B; AltName: Full=Alpha-IPM
            synthase B; AltName: Full=Alpha-isopropylmalate synthase
            B gi|2213884|gb|AAB61599.1| 2-isopropylmalate synthase
            [Solanum pennellii]
          Length = 612

 Score =  887 bits (2293), Expect = 0.0
 Identities = 457/572 (79%), Positives = 504/572 (88%), Gaps = 7/572 (1%)
 Frame = +1

Query: 292  RALLHFKPSRIP-SRKLFSIV---CSSR--PEYIPNHIPDPNYVRIFDTTLRDGEQSPGA 453
            + L +FKPS    S   FSI    CS R  PEY P+HIPDPNYVRIFDTTLRDGEQSPGA
Sbjct: 28   QTLFNFKPSISKHSNSSFSIPVVRCSIRRIPEYTPSHIPDPNYVRIFDTTLRDGEQSPGA 87

Query: 454  TMTTKEKLDIARQLAKLGVDIIEAGFPASSQADLEAVKLIAQEVGNMGAGEDGHVPVICG 633
            TMTTKEKLD+ARQ AKLGVDIIEAGFPASS+ADLEAVKLIA+EVGN G  E+ +VPVICG
Sbjct: 88   TMTTKEKLDVARQSAKLGVDIIEAGFPASSEADLEAVKLIAKEVGN-GVYEEEYVPVICG 146

Query: 634  LSRCNKNDIDKAWEAVKHAKFPRIHTFIATSEIHMQYKLNMSKEQVIEKARSMVAYARSL 813
            L+RCNK DIDKAWEAVK+AK PRIHTFIATSE+HM YKL MS++QV+EKARSMVAYARS+
Sbjct: 147  LARCNKKDIDKAWEAVKYAKKPRIHTFIATSEVHMNYKLKMSRDQVVEKARSMVAYARSI 206

Query: 814  GCNDVEFSPEDAGRSEREFLYEILGEVIKAGATTLNIPDTVGYNWPREFGQLIADIRANT 993
            GC DVEFSPEDAGRS+ EFLY ILGEVIKAGATTLNIPDTVGY  P EFGQLIA I+ANT
Sbjct: 207  GCEDVEFSPEDAGRSDPEFLYHILGEVIKAGATTLNIPDTVGYTVPEEFGQLIAKIKANT 266

Query: 994  PGIENVIISTHCQNDLGLSTANTLEGAYSGARQLEVTINGIGERAGNASLEEVVMTIKCK 1173
            PG+E+VIISTHCQNDLGLSTANTL GA +GARQLEVTINGIGERAGNASLEEVVM +KC+
Sbjct: 267  PGVEDVIISTHCQNDLGLSTANTLAGACAGARQLEVTINGIGERAGNASLEEVVMALKCR 326

Query: 1174 GE-VLGGLYTGINTRHIVMASKMVEEYSGLLVQPHKAIVGANAFAHESGIHQDGMLKNKS 1350
            GE VLGGLYTGINT+HI+M+SKMVE  SGL VQPHKAIVGANAF HESGIHQDGMLK+K 
Sbjct: 327  GEQVLGGLYTGINTQHILMSSKMVEGISGLHVQPHKAIVGANAFVHESGIHQDGMLKHKD 386

Query: 1351 TYEIMSPEDIGLFRSNESGLTLGKLSGRHALKSKLFELGYDIDGKELNDLFWRFKSVAEM 1530
            TYEI+SPEDIGL R+NESG+  GKLSG    K K+ ELGY+I+GKEL+DLFWRFKSVAE 
Sbjct: 387  TYEIISPEDIGLNRANESGIVFGKLSGVMLCKPKMLELGYEIEGKELDDLFWRFKSVAEK 446

Query: 1531 KKVITDDDLVALVSDEVFQPQVVWKFGDVQVTCGTLGLSTATVKLIDSDGKEHIACSTGT 1710
            KK ITDDDLVAL+SDEVFQPQ VW+  +VQVTCG+LGLSTATVKLID+DG+EHI+CS GT
Sbjct: 447  KKKITDDDLVALMSDEVFQPQFVWQLQNVQVTCGSLGLSTATVKLIDADGREHISCSVGT 506

Query: 1711 GPVDAAYKAVDLIVKVPVKLLEYSMSAVTAGIDALASTRVLISGENTHIATHASTGEKIV 1890
            GPVDAAYKAVDLIVKVPV LLEYSM+AVT GIDA+ASTRVLI GEN H +THA TGE + 
Sbjct: 507  GPVDAAYKAVDLIVKVPVTLLEYSMNAVTQGIDAIASTRVLIRGENGHTSTHALTGETVH 566

Query: 1891 RTYSGTGASMDIVISSVRAYVGALNKMLGLKK 1986
            RT+SGTGA MDIVISSVRAYVGALNKM+  +K
Sbjct: 567  RTFSGTGADMDIVISSVRAYVGALNKMMSFRK 598


>ref|XP_002268942.2| PREDICTED: 2-isopropylmalate synthase 2, chloroplastic-like [Vitis
            vinifera]
          Length = 628

 Score =  875 bits (2260), Expect = 0.0
 Identities = 444/576 (77%), Positives = 500/576 (86%), Gaps = 9/576 (1%)
 Frame = +1

Query: 289  IRALLHFKPSRIPSRKLFSIVCSSR--------PEYIPNHIPDPNYVRIFDTTLRDGEQS 444
            I + L FKP   PS  L + V S R        PEYIPN I DPNYVRIFDTTLRDGEQS
Sbjct: 43   IPSTLFFKP---PSHSLATKVLSHRLPVRSALRPEYIPNRIDDPNYVRIFDTTLRDGEQS 99

Query: 445  PGATMTTKEKLDIARQLAKLGVDIIEAGFPASSQADLEAVKLIAQEVGNMGAGEDGHVPV 624
            PGATMT+KEKLDIARQLAKLGVDIIEAGFPA+S+ DL+AVK+IA+EVGN    E+GHVPV
Sbjct: 100  PGATMTSKEKLDIARQLAKLGVDIIEAGFPAASKDDLDAVKIIAKEVGN-AVDENGHVPV 158

Query: 625  ICGLSRCNKNDIDKAWEAVKHAKFPRIHTFIATSEIHMQYKLNMSKEQVIEKARSMVAYA 804
            ICGL+RCN+NDI  AWEAVK+AK PRIHTFIATSEIHM+YKL  S+++VIE AR MV YA
Sbjct: 159  ICGLARCNRNDISTAWEAVKYAKRPRIHTFIATSEIHMKYKLKKSEKEVIEIAREMVKYA 218

Query: 805  RSLGCNDVEFSPEDAGRSEREFLYEILGEVIKAGATTLNIPDTVGYNWPREFGQLIADIR 984
            RSLGC+DVEFSPEDAGRSEREFLY+ILGEVIKAGATTLNIPDTVGY  P EFGQLIADI+
Sbjct: 219  RSLGCDDVEFSPEDAGRSEREFLYKILGEVIKAGATTLNIPDTVGYTVPNEFGQLIADIK 278

Query: 985  ANTPGIENVIISTHCQNDLGLSTANTLEGAYSGARQLEVTINGIGERAGNASLEEVVMTI 1164
            +NTPGIENVIISTHCQNDLGLSTANT+ GA +GARQ+EVTINGIGERAGNASLEEVVM +
Sbjct: 279  SNTPGIENVIISTHCQNDLGLSTANTIAGACAGARQVEVTINGIGERAGNASLEEVVMAL 338

Query: 1165 KCKGE-VLGGLYTGINTRHIVMASKMVEEYSGLLVQPHKAIVGANAFAHESGIHQDGMLK 1341
            KC+GE  LGGLYTGIN RHIV  SKMV EYSGL VQPHKAIVGANAFAHESGIHQDGMLK
Sbjct: 339  KCRGEKALGGLYTGINIRHIVKTSKMVAEYSGLQVQPHKAIVGANAFAHESGIHQDGMLK 398

Query: 1342 NKSTYEIMSPEDIGLFRSNESGLTLGKLSGRHALKSKLFELGYDIDGKELNDLFWRFKSV 1521
            +K TYEI+SPEDIGLFRSNESG+ LGKLSGRHALKS+L ELGY+I+G EL+D+FWRFK V
Sbjct: 399  HKETYEIISPEDIGLFRSNESGIVLGKLSGRHALKSRLLELGYEIEGMELDDIFWRFKEV 458

Query: 1522 AEMKKVITDDDLVALVSDEVFQPQVVWKFGDVQVTCGTLGLSTATVKLIDSDGKEHIACS 1701
            AE KK +TD D++ALVSDE+FQP+V WK GD+QVTCGTLGLSTATVKLID+DG++H+ACS
Sbjct: 459  AEKKKNLTDVDVIALVSDEIFQPKVFWKLGDLQVTCGTLGLSTATVKLIDADGQKHVACS 518

Query: 1702 TGTGPVDAAYKAVDLIVKVPVKLLEYSMSAVTAGIDALASTRVLISGENTHIATHASTGE 1881
             GTGPVD+AYKA+DL+VK  V LLEY ++AVT GIDA+A+TRVLI GE  H  T+A TGE
Sbjct: 519  VGTGPVDSAYKAIDLLVKEQVTLLEYGLNAVTEGIDAIATTRVLIRGEKNHTLTNALTGE 578

Query: 1882 KIVRTYSGTGASMDIVISSVRAYVGALNKMLGLKKQ 1989
             + R++SGTGA MDIV+SSVRAY+ ALNKMLG K Q
Sbjct: 579  TVHRSFSGTGAGMDIVVSSVRAYISALNKMLGFKDQ 614


>ref|XP_002530549.1| isopropylmalate synthase, putative [Ricinus communis]
            gi|223529911|gb|EEF31840.1| isopropylmalate synthase,
            putative [Ricinus communis]
          Length = 632

 Score =  868 bits (2243), Expect = 0.0
 Identities = 444/589 (75%), Positives = 505/589 (85%), Gaps = 24/589 (4%)
 Frame = +1

Query: 295  ALLHFKPSR------------IPSRKLF----SIVCSS-------RPEYIPNHIPDPNYV 405
            +LLHF P+R             PS   F    +I CSS       RPEYIP+HIPDP+YV
Sbjct: 29   SLLHFTPTRCRFFSNSKFSVSFPSNSRFKSSTAISCSSSAAPLSRRPEYIPSHIPDPSYV 88

Query: 406  RIFDTTLRDGEQSPGATMTTKEKLDIARQLAKLGVDIIEAGFPASSQADLEAVKLIAQEV 585
            RIFDTTLRDGEQSPGAT+T+KEKLDIARQL+KLGVDIIEAGFPA+S+ D EAVK IA+EV
Sbjct: 89   RIFDTTLRDGEQSPGATLTSKEKLDIARQLSKLGVDIIEAGFPAASKDDFEAVKTIAKEV 148

Query: 586  GNMGAGEDGHVPVICGLSRCNKNDIDKAWEAVKHAKFPRIHTFIATSEIHMQYKLNMSKE 765
            GN    EDG+VPVICGLSRCN+ DI  AWEAVK+AK PRIHTFIATS IHM+YKL  SKE
Sbjct: 149  GN-AVDEDGYVPVICGLSRCNEKDIRTAWEAVKYAKRPRIHTFIATSAIHMEYKLRKSKE 207

Query: 766  QVIEKARSMVAYARSLGCNDVEFSPEDAGRSEREFLYEILGEVIKAGATTLNIPDTVGYN 945
            +V+E ARSMV +ARSLGC+DVEFSPEDAGRS+REFLY ILGEVIKAGATTLNIPDTVG  
Sbjct: 208  EVVEIARSMVKFARSLGCDDVEFSPEDAGRSDREFLYHILGEVIKAGATTLNIPDTVGIT 267

Query: 946  WPREFGQLIADIRANTPGIENVIISTHCQNDLGLSTANTLEGAYSGARQLEVTINGIGER 1125
             P EFGQLIADI+ANTPGI+ VIISTHCQNDLGLSTANTL GAY+GARQ+EVTINGIGER
Sbjct: 268  LPSEFGQLIADIKANTPGIDKVIISTHCQNDLGLSTANTLAGAYAGARQVEVTINGIGER 327

Query: 1126 AGNASLEEVVMTIKCKGE-VLGGLYTGINTRHIVMASKMVEEYSGLLVQPHKAIVGANAF 1302
            AGNASLEEVVM IKC+GE +LGGLYTGIN R I MASKMVEEY+GL +QPHKAIVGANAF
Sbjct: 328  AGNASLEEVVMAIKCRGEHILGGLYTGINPRQITMASKMVEEYTGLHLQPHKAIVGANAF 387

Query: 1303 AHESGIHQDGMLKNKSTYEIMSPEDIGLFRSNESGLTLGKLSGRHALKSKLFELGYDIDG 1482
            AHESGIHQDGMLK+K TYEI+SPEDIGL RSN++G+ LGKLSGRHALK +L ELGY+++ 
Sbjct: 388  AHESGIHQDGMLKHKGTYEIISPEDIGLERSNDAGIVLGKLSGRHALKDRLKELGYELND 447

Query: 1483 KELNDLFWRFKSVAEMKKVITDDDLVALVSDEVFQPQVVWKFGDVQVTCGTLGLSTATVK 1662
            ++L  +FWRFK+VAE KK +TD DL+ALVSDEVFQP++VWK GD+QVTCGTLGLSTATVK
Sbjct: 448  EQLGTIFWRFKAVAETKKRVTDADLIALVSDEVFQPEIVWKLGDLQVTCGTLGLSTATVK 507

Query: 1663 LIDSDGKEHIACSTGTGPVDAAYKAVDLIVKVPVKLLEYSMSAVTAGIDALASTRVLISG 1842
            LI++DG+EHIACS G+GPVDA YKAVDLIVK PV+LLEYSM+AVT GIDA+A+TRVLI  
Sbjct: 508  LINADGEEHIACSVGSGPVDAGYKAVDLIVKEPVELLEYSMNAVTEGIDAIATTRVLIRR 567

Query: 1843 ENTHIATHASTGEKIVRTYSGTGASMDIVISSVRAYVGALNKMLGLKKQ 1989
            E+ H +THA TGE   RT+SG+GA MDIV+SSV+AYVGALNKML LK+Q
Sbjct: 568  EDNHTSTHALTGEPFQRTFSGSGAGMDIVVSSVKAYVGALNKMLALKQQ 616