BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Angelica27_contig00003205
         (3189 letters)

Database: ./nr 
           115,041,592 sequences; 42,171,959,267 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_017241904.1 PREDICTED: DNA topoisomerase 1-like [Daucus carot...  1401   0.0  
CAB46363.1 DNA topoisomerase I [Daucus carota]                       1258   0.0  
XP_011093631.1 PREDICTED: DNA topoisomerase 1-like [Sesamum indi...  1068   0.0  
BAG31376.1 topoisomerase I [Camptotheca acuminata]                   1066   0.0  
BAK32960.1 topoisomerase I [Ophiorrhiza pseudofasciculata]           1045   0.0  
CDP13767.1 unnamed protein product [Coffea canephora]                1042   0.0  
BAG31377.1 topoisomerase I [Catharanthus roseus]                     1037   0.0  
BAG31375.1 topoisomerase I [Ophiorrhiza japonica]                    1031   0.0  
BAK32956.1 topoisomerase I [Ophiorrhiza fucosa]                      1025   0.0  
BAG31373.1 topoisomerase I [Ophiorrhiza pumila]                      1023   0.0  
BAK32962.1 topoisomerase I [Ophiorrhiza trichocarpon var. glabra]    1022   0.0  
BAK32958.1 topoisomerase I [Ophiorrhiza pedunculata]                 1021   0.0  
BAG31374.1 topoisomerase I [Ophiorrhiza liukiuensis]                 1020   0.0  
XP_010266803.1 PREDICTED: DNA topoisomerase 1 alpha-like [Nelumb...  1020   0.0  
XP_012845487.1 PREDICTED: DNA topoisomerase 1-like [Erythranthe ...  1014   0.0  
BAK32961.1 topoisomerase I [Ophiorrhiza ridleyana]                   1013   0.0  
BAK32963.1 topoisomerase I [Ophiorrhiza sp. 35]                      1011   0.0  
KZV21640.1 DNA topoisomerase 1-like [Dorcoceras hygrometricum]       1008   0.0  
XP_016684952.1 PREDICTED: DNA topoisomerase 1-like [Gossypium hi...  1003   0.0  
BAK32957.1 topoisomerase I [Ophiorrhiza harrisiana]                  1003   0.0  

>XP_017241904.1 PREDICTED: DNA topoisomerase 1-like [Daucus carota subsp. sativus]
            KZN00059.1 hypothetical protein DCAR_008813 [Daucus
            carota subsp. sativus]
          Length = 895

 Score = 1401 bits (3627), Expect = 0.0
 Identities = 723/900 (80%), Positives = 756/900 (84%), Gaps = 3/900 (0%)
 Frame = -2

Query: 2957 MENGSDSEDDRPLVFKRSTPLVKHNQVKPDVKKTSMQKPDGKSGRQMSDVRSPNGNGNGQ 2778
            ME+GSDSEDD+PL+FKRS   VK NQ KPDVKK+S+QKPDGKSGR +SDVRS NG+    
Sbjct: 1    MEHGSDSEDDKPLIFKRSNTSVKQNQAKPDVKKSSVQKPDGKSGRPISDVRSTNGH---- 56

Query: 2777 DSNIQKGKTGPSTKGXXXXXXXXXXXXXXXXXXXXXXXXPLASTKASTSGADRSRQNIQQ 2598
            DSN+QKGKT PSTKG                        P+ STKASTSGAD+SRQN QQ
Sbjct: 57   DSNVQKGKTVPSTKGSPVVSPLASPKASVSSSKASQVKPPVGSTKASTSGADQSRQNSQQ 116

Query: 2597 NKTATVKVDKPSGXXXXXXXXXXXXXXXP--LNSRLPVGGSKGSISVVNKRPGSSGPASL 2424
            N+TA VK ++PSG                  LNSRLPVGGSKGSIS VN+RP SSGPA+L
Sbjct: 117  NRTAIVKAERPSGIPKEEPDSGSEDSDDDKPLNSRLPVGGSKGSISEVNRRPSSSGPAAL 176

Query: 2423 AKPDPGVKEEDSEDDIPLSHKFKQKSNAGESSNANDSDV-KPFASKHQQNGTSARDNVKN 2247
            AK D G+KEEDSEDDIPLSHKFKQKSNAGESSNA DSD  KPFASK +QNGT+ +DNVKN
Sbjct: 177  AK-DLGIKEEDSEDDIPLSHKFKQKSNAGESSNAYDSDEGKPFASKPRQNGTNVKDNVKN 235

Query: 2246 PSPGLNKRPSAEVKCSGQSPVKKAKHAAASTPVNGKKVSVKAEPKKEXXXXXXDYATISQ 2067
            PS  +NKRPSAEVKCSGQSPVKKAKH AASTPVNGKKV+VKAEPKKE      D ATISQ
Sbjct: 236  PSTAINKRPSAEVKCSGQSPVKKAKHTAASTPVNGKKVTVKAEPKKEADDSDDDNATISQ 295

Query: 2066 RLKKPVTPIXXXXXXXXXXXXXXXXXXXXXXXXXKITKSTQFSKSLNVPPGSGEGQKWTT 1887
            R+KKP TPI                         KITKSTQFSKSL VPPGSGEGQKWTT
Sbjct: 296  RVKKPATPISKASDKKKSAVSVSSSLNKVNKNSKKITKSTQFSKSLKVPPGSGEGQKWTT 355

Query: 1886 LVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAVMQDTDYMTKPVFRENVMND 1707
            LVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAVMQDT+YMTKPVFRENVMND
Sbjct: 356  LVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAVMQDTEYMTKPVFRENVMND 415

Query: 1706 WKKILGRNHIIKNLDDCDFTPIYEWHQSEKEKKKQMSAXXXXXXXXXXXXXXXKYMWAIV 1527
            WKKILGRNHIIKNLDDCDFTPIYEWHQ+EKEKKKQMSA               KYMWA+V
Sbjct: 416  WKKILGRNHIIKNLDDCDFTPIYEWHQTEKEKKKQMSAEEKKAVKEEKLKQEEKYMWAVV 475

Query: 1526 DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITINIGKDAPIPECPIPGESWK 1347
            DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI PSDITINIGKDAPIPECPIPGESWK
Sbjct: 476  DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRISPSDITINIGKDAPIPECPIPGESWK 535

Query: 1346 EVRHDNTVTWLAYWLDPINGKEFKYVFLAASSSLKGQSDKEKYEKARKLKGYIAGIRTAY 1167
            EVRHDNTVTWLAYW DPINGKEFKYVFLAASSSLKGQSDKEKYEKARKLKGYI GIRTAY
Sbjct: 536  EVRHDNTVTWLAYWNDPINGKEFKYVFLAASSSLKGQSDKEKYEKARKLKGYIEGIRTAY 595

Query: 1166 TKDFANKDTAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPSPPNILKL 987
            TKDF++KD  KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPSPPNILKL
Sbjct: 596  TKDFSSKDVTKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPSPPNILKL 655

Query: 986  DFLGKDSIRYQNEVEVEIPVFKAIQQFRSGKEGSDNLFDKLDTTKLNAHLKELMPGLSAK 807
            DFLGKDSIRYQNEVEVEIPVFKAIQQFRSGK+GSDNLFDKLDT+KLNAHLKELMPGLSAK
Sbjct: 656  DFLGKDSIRYQNEVEVEIPVFKAIQQFRSGKKGSDNLFDKLDTSKLNAHLKELMPGLSAK 715

Query: 806  VFRTYNASITLDDMLNKETKGGDVSQKVAVYQHANKEVAIICNHQRTVSKSHSTQMLRXX 627
            VFRTYNASITLD+MLNKETKGGDVSQKVAVYQHANKEVAIICNHQR+VSKSHSTQM+R  
Sbjct: 716  VFRTYNASITLDEMLNKETKGGDVSQKVAVYQHANKEVAIICNHQRSVSKSHSTQMMRLD 775

Query: 626  XXXXXXXXXXXXXXXXLSRAKKGKPPLKGSDGKTKRNMNPEALEKKIAQTNTKIEKMERD 447
                            LSRAKKGKPPLKGSDGKTKRNMNPEA+EKKIAQTN KIEKMERD
Sbjct: 776  EKINELKNLIEELKTDLSRAKKGKPPLKGSDGKTKRNMNPEAIEKKIAQTNVKIEKMERD 835

Query: 446  KEIKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMFNKSLLAKFAWAMDVEPSFRF 267
            KE KEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMFNKSLLAKFAWAMDVEPSFRF
Sbjct: 836  KETKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMFNKSLLAKFAWAMDVEPSFRF 895


>CAB46363.1 DNA topoisomerase I [Daucus carota]
          Length = 909

 Score = 1258 bits (3255), Expect = 0.0
 Identities = 676/917 (73%), Positives = 714/917 (77%), Gaps = 20/917 (2%)
 Frame = -2

Query: 2957 MENGSDSEDDRPLVFKRSTPLVKHNQVKPDVKKTSMQKPDGKSGRQMSDVRSPNGNGNGQ 2778
            ME+GSDSEDD+PL+FKRS   VK NQ KP  +K    +   + GR +SDVRS NG+    
Sbjct: 1    MEHGSDSEDDKPLIFKRSNTSVKQNQAKPRCQKIISAEAVWQVGRLISDVRSTNGH---- 56

Query: 2777 DSNIQKGKTGPSTKGXXXXXXXXXXXXXXXXXXXXXXXXPLASTKASTSGADRSRQNIQQ 2598
            DSN+QKGKT PSTKG                        P+ASTKASTSGAD+SRQN QQ
Sbjct: 57   DSNVQKGKTVPSTKGSPVVSPLASPKASVSSSKASQVKPPVASTKASTSGADQSRQNSQQ 116

Query: 2597 NKTATVKVDKPSGXXXXXXXXXXXXXXXP--LNSRLPVGGSKGSISVVNKRPGSSGPASL 2424
            N+TA VK ++PSG                  LNSRLPVGGSKGSIS VN+RP SSGPA+ 
Sbjct: 117  NRTAIVKAERPSGIPKEEPDSGSEDSDDDKPLNSRLPVGGSKGSISEVNRRPSSSGPAAF 176

Query: 2423 AKPDPGVKEEDSEDDIPLSHKFKQKSNAGESSNANDSDV-KPFASKHQQNGTSARDNVKN 2247
             K D G+KEEDSEDDIPLSHKFKQKSNAGESSNA DSD  KPFASK +QNGT+ +DNVKN
Sbjct: 177  EK-DLGIKEEDSEDDIPLSHKFKQKSNAGESSNAYDSDEGKPFASKPRQNGTNVKDNVKN 235

Query: 2246 PSPGLNKRPSAEVKCSGQSPVKKAKHAAASTPVNGKKVSVKAEPKKEXXXXXXDYATISQ 2067
            PS  +NKRPSAEVKCSGQSPVKKA        V  +K++VKAEPKKE      D ATISQ
Sbjct: 236  PSTAINKRPSAEVKCSGQSPVKKATVQLHLHQV--RKLTVKAEPKKEADDSDDDNATISQ 293

Query: 2066 RLKKPVTPIXXXXXXXXXXXXXXXXXXXXXXXXXKITKSTQFSKSLNVPPGSGEGQKWTT 1887
            R+KKP TPI                         KITKSTQFSKSL VPPGSGEGQKWTT
Sbjct: 294  RVKKPATPISKASDKKKSAVSVSSSLNKVNKNSKKITKSTQFSKSLKVPPGSGEGQKWTT 353

Query: 1886 LVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAVMQD-TDYMTKPVFRENVMN 1710
            LVHNGVIFPPPYKPHGVKMLYK  PVDLT  QEEV  MIAVMQ  T+Y+TKPVFRENVMN
Sbjct: 354  LVHNGVIFPPPYKPHGVKMLYKESPVDLTLNQEEVH-MIAVMQILTEYLTKPVFRENVMN 412

Query: 1709 DWKKILGRNHIIKNLDDCDFTPIYEWHQSEKEKKKQMSAXXXXXXXXXXXXXXXKYMWAI 1530
            DWK ILGRNHIIKNLDDCDFTPIYEW + +KEKKKQMSA               KYMWA+
Sbjct: 413  DWKIILGRNHIIKNLDDCDFTPIYEWFRLKKEKKKQMSAEEKKAVKEEKLKQEEKYMWAV 472

Query: 1529 VDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITINIGKDAPIPECPIPGESW 1350
            VDGVKE VGNFRVEPPGLFRGR   PKMGKLKKRI PSDITINIGKDAPIPECPIPGESW
Sbjct: 473  VDGVKENVGNFRVEPPGLFRGRESIPKMGKLKKRISPSDITINIGKDAPIPECPIPGESW 532

Query: 1349 KEVRHDNTVTWLAYWLDPINGKEFKYVFLAASSSLKGQSDKEKYEKARKLKGYIAGIRTA 1170
            KEVRHDNTVTWLAYW DPINGKEFKYVFLAASSSLKGQSDKEKYEKARKLKGYI GIRTA
Sbjct: 533  KEVRHDNTVTWLAYWNDPINGKEFKYVFLAASSSLKGQSDKEKYEKARKLKGYIEGIRTA 592

Query: 1169 YTKDFANKDTAKRQIAVATYLIDKLALRAGN----------------EKDDDEADTVGCC 1038
            YTKDF++KD  KRQIAVATYLIDKLALRAGN                EKDDDEADTVGCC
Sbjct: 593  YTKDFSSKDVTKRQIAVATYLIDKLALRAGNAVATYLIDKLALRAGNEKDDDEADTVGCC 652

Query: 1037 TLKVENVEPSPPNILKLDFLGKDSIRYQNEVEVEIPVFKAIQQFRSGKEGSDNLFDKLDT 858
            TLKVENVEP    +LKLDFL KDSIRYQ  VEVEIPVFKAIQQFRSGK+GSDNLFDKLDT
Sbjct: 653  TLKVENVEPRNNPLLKLDFLPKDSIRYQKRVEVEIPVFKAIQQFRSGKKGSDNLFDKLDT 712

Query: 857  TKLNAHLKELMPGLSAKVFRTYNASITLDDMLNKETKGGDVSQKVAVYQHANKEVAIICN 678
             KLNAHLKELMPGLSAKVFRTYNASITLD+MLNKETKGGDVSQKVAVYQHANKEVAIICN
Sbjct: 713  CKLNAHLKELMPGLSAKVFRTYNASITLDEMLNKETKGGDVSQKVAVYQHANKEVAIICN 772

Query: 677  HQRTVSKSHSTQMLRXXXXXXXXXXXXXXXXXXLSRAKKGKPPLKGSDGKTKRNMNPEAL 498
            HQR+VSKSHSTQM+R                  LSRAKKGKPPLKGSDGKTKRNMNPEA+
Sbjct: 773  HQRSVSKSHSTQMMRLDEKINKLKNFIEELKTDLSRAKKGKPPLKGSDGKTKRNMNPEAI 832

Query: 497  EKKIAQTNTKIEKMERDKEIKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMFNKS 318
            EKKIAQTN KIEKMERDKE KEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMFNKS
Sbjct: 833  EKKIAQTNVKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMFNKS 892

Query: 317  LLAKFAWAMDVEPSFRF 267
            LLAKFAWAMDVEPSFRF
Sbjct: 893  LLAKFAWAMDVEPSFRF 909


>XP_011093631.1 PREDICTED: DNA topoisomerase 1-like [Sesamum indicum]
          Length = 893

 Score = 1068 bits (2762), Expect = 0.0
 Identities = 571/894 (63%), Positives = 644/894 (72%), Gaps = 4/894 (0%)
 Frame = -2

Query: 2936 EDDRPLVFKRSTPLVKHNQVKPDVKKTSMQKPDGKSGRQMSDVRSPNGNGNGQDSNIQKG 2757
            EDD PLVFKRS+   K +Q   + K+   QK D    R   DVR  NG    Q + IQK 
Sbjct: 17   EDDEPLVFKRSSSSAKQSQGNSETKRPLSQKHDRPLNRPSPDVRPQNG----QSTMIQKS 72

Query: 2756 KTGPSTKGXXXXXXXXXXXXXXXXXXXXXXXXPLASTKASTSGADRSRQNIQQNKTATVK 2577
            KT PS++                              + STS  D S     Q     +K
Sbjct: 73   KTVPSSRTPPLRSPLASPKSSNSSAKALAVRPREVDPRPSTSVTDESNSVKHQ-----IK 127

Query: 2576 VDKPS--GXXXXXXXXXXXXXXXPLNSRLPVGGSKGSISVVNKRPGSSGPASLAKPDPGV 2403
             +KPS                  PL++RLP G SK + +  NK P +       K     
Sbjct: 128  DEKPSTKATGGLNEDSEDSEDDKPLSARLPAGLSKVNSNHANKGPNALTSVQKTKIP--- 184

Query: 2402 KEEDSEDDIPLSHKFKQKSNAGESSN--ANDSDVKPFASKHQQNGTSARDNVKNPSPGLN 2229
            K EDS+D+IPLS KF+ KSNAGES+N  +   + KP  +K+ QNG+++ +  + PS  L 
Sbjct: 185  KPEDSDDEIPLSSKFQVKSNAGESTNRPSISGERKPLLAKYDQNGSASAE--RKPSTILK 242

Query: 2228 KRPSAEVKCSGQSPVKKAKHAAASTPVNGKKVSVKAEPKKEXXXXXXDYATISQRLKKPV 2049
            KRP+  VK +G+S +KK K + ASTP   K+ S+K E K E       +  ISQR+K+  
Sbjct: 243  KRPADGVKSAGESYLKKPKLSDASTPNKTKETSIKDEMKDEDDED---HVPISQRIKQQT 299

Query: 2048 TPIXXXXXXXXXXXXXXXXXXXXXXXXXKITKSTQFSKSLNVPPGSGEGQKWTTLVHNGV 1869
            +                           K+ K++++SKS  VPP SGEGQKWTTLVHNGV
Sbjct: 300  SSDKKSSSAKNMTKPISASAKKTSKKPKKVMKNSKYSKSSKVPPSSGEGQKWTTLVHNGV 359

Query: 1868 IFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAVMQDTDYMTKPVFRENVMNDWKKILG 1689
            IFPPPYKPHGVKMLYKGKPVDLTPEQEEVATM AVM DTDYM KP F+EN M DW+KILG
Sbjct: 360  IFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLDTDYMNKPKFKENFMADWRKILG 419

Query: 1688 RNHIIKNLDDCDFTPIYEWHQSEKEKKKQMSAXXXXXXXXXXXXXXXKYMWAIVDGVKEK 1509
            +NH+I++L+ CDFTPIYEWHQ EKEKKKQM+A               KYMWAIV+GVKEK
Sbjct: 420  KNHVIQSLEHCDFTPIYEWHQKEKEKKKQMTAEEKKALKEEKLKQEEKYMWAIVNGVKEK 479

Query: 1508 VGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITINIGKDAPIPECPIPGESWKEVRHDN 1329
            VGNFRVEPPGLFRGRGEHPKMGKLKKRI PSDITINIGKDAPIPECPIPGESWKE+RHDN
Sbjct: 480  VGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWKEIRHDN 539

Query: 1328 TVTWLAYWLDPINGKEFKYVFLAASSSLKGQSDKEKYEKARKLKGYIAGIRTAYTKDFAN 1149
            TVTWLAYW DPIN KEFKYVFLAASS+LKGQSDKEKYEKAR LK YI GIR AYTKDF N
Sbjct: 540  TVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTN 599

Query: 1148 KDTAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPSPPNILKLDFLGKD 969
            KD  K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP PPNILK DFLGKD
Sbjct: 600  KDPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKD 659

Query: 968  SIRYQNEVEVEIPVFKAIQQFRSGKEGSDNLFDKLDTTKLNAHLKELMPGLSAKVFRTYN 789
            SIRYQNEVEVE PVFKAIQQFRSGK+GSD++FD+LDT+KLNAHLKELMPGL+AKVFRTYN
Sbjct: 660  SIRYQNEVEVETPVFKAIQQFRSGKKGSDDMFDRLDTSKLNAHLKELMPGLTAKVFRTYN 719

Query: 788  ASITLDDMLNKETKGGDVSQKVAVYQHANKEVAIICNHQRTVSKSHSTQMLRXXXXXXXX 609
            ASITLDD L++ETKGGDV++KV VYQHANKEVAIICNHQRTVSKSHS QM R        
Sbjct: 720  ASITLDDKLSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMTRLNEKIEEL 779

Query: 608  XXXXXXXXXXLSRAKKGKPPLKGSDGKTKRNMNPEALEKKIAQTNTKIEKMERDKEIKED 429
                      L+RAKKGKPPLK +DGK KRN+NP+ALEKKIAQTN KIEKMERDKE KED
Sbjct: 780  KGVLEELQTDLARAKKGKPPLKSADGKPKRNLNPDALEKKIAQTNAKIEKMERDKETKED 839

Query: 428  LKTVALGTSKINYLDPRITVAWCKRYEVPIEKMFNKSLLAKFAWAMDVEPSFRF 267
            LKTVALGTSKINYLDPRITVAWCKR+EVPIEK+FNKSLLAKFAWAMDV+PSFRF
Sbjct: 840  LKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPSFRF 893


>BAG31376.1 topoisomerase I [Camptotheca acuminata]
          Length = 894

 Score = 1066 bits (2757), Expect = 0.0
 Identities = 572/895 (63%), Positives = 652/895 (72%), Gaps = 5/895 (0%)
 Frame = -2

Query: 2936 EDDRPLVFKRSTPLVKHNQVKPDVKKTSMQKPDGKSGRQMSDVRSPNGNGNGQDSNIQKG 2757
            EDD PLVFKRS    KHNQ+  D KK+S Q+ DG+SGRQ+SDV S NG    Q S+  KG
Sbjct: 17   EDDEPLVFKRSNATSKHNQLNSDTKKSS-QRYDGQSGRQVSDVPSTNG----QSSSASKG 71

Query: 2756 KTGPSTKGXXXXXXXXXXXXXXXXXXXXXXXXPLASTKASTSGADRSRQNIQQNKTATVK 2577
            KT   +                          P+A+ K S+S  DRS+ + +QN    VK
Sbjct: 72   KTTKLSS-------MKSPIASPKASTSFAKASPVANPKVSSSSDDRSKHSSKQNTINVVK 124

Query: 2576 VDKPSGXXXXXXXXXXXXXXXPLNSRLPVGGSKGSISVVNKRPGSSGPASLAKPDPGVKE 2397
             +K                  PL++RL  G +KGS +  NK   +S PASL  P P +  
Sbjct: 125  EEKEL-VNPAAEPYGDSEDEKPLSARLFTGLTKGSSNNANKGLINSSPASLPVPKPEINR 183

Query: 2396 --EDSEDDIPLSHKFKQKSNAGESS--NANDSDVKPFASKHQQNGTSARDNVKNPSPGLN 2229
              +DS+D+IPLS KF+ K+NAG S+  +    D K   S  QQNG+  R +    S  +N
Sbjct: 184  YSDDSDDEIPLSSKFRLKANAGTSTVKSYESDDNKTLVSNFQQNGSINRGS--KSSIKVN 241

Query: 2228 KRPSAEVKCSGQSPVKKAKHAAASTPVNGKKVSVKAEPKKEXXXXXXDYATISQRLKKPV 2049
            KRP  EVK S QS VKK K + ASTPVN K+ S KAEPK +       +  ISQR+KK  
Sbjct: 242  KRPLGEVKSSVQSSVKKPKLSDASTPVNNKQASKKAEPKADDSDDD--HVPISQRMKKSA 299

Query: 2048 TP-IXXXXXXXXXXXXXXXXXXXXXXXXXKITKSTQFSKSLNVPPGSGEGQKWTTLVHNG 1872
            T                            K+ K +++SKS  VPP SGEG+KW TLVHNG
Sbjct: 300  TSGNKSSTAKQKVTKVVSSSMKKASKKFKKVVKKSKYSKSSKVPPSSGEGKKWNTLVHNG 359

Query: 1871 VIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAVMQDTDYMTKPVFRENVMNDWKKIL 1692
            VIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATM AVM DTDYMTK  F+EN M+DW+KIL
Sbjct: 360  VIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMTKSKFKENFMDDWRKIL 419

Query: 1691 GRNHIIKNLDDCDFTPIYEWHQSEKEKKKQMSAXXXXXXXXXXXXXXXKYMWAIVDGVKE 1512
            G+NH+I+NL+DCDFTPIYEWHQ EKEKKK+M+A               KYMWAIV+GVKE
Sbjct: 420  GKNHVIQNLEDCDFTPIYEWHQREKEKKKKMTAEEKKVLKEERLKQEEKYMWAIVNGVKE 479

Query: 1511 KVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITINIGKDAPIPECPIPGESWKEVRHD 1332
            KVGNFRVEPP LFRGRGEHPKMGKLKK I PSDITINIGKDAPIPECPIPGESWKE+RHD
Sbjct: 480  KVGNFRVEPPSLFRGRGEHPKMGKLKKCIRPSDITINIGKDAPIPECPIPGESWKEIRHD 539

Query: 1331 NTVTWLAYWLDPINGKEFKYVFLAASSSLKGQSDKEKYEKARKLKGYIAGIRTAYTKDFA 1152
            NTVTWLA+W DPI  +EFKYVFLAASSSLKGQSDKEKYEKAR LK +I GIR AYTKDFA
Sbjct: 540  NTVTWLAFWNDPIKPREFKYVFLAASSSLKGQSDKEKYEKARLLKDFIQGIRAAYTKDFA 599

Query: 1151 NKDTAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPSPPNILKLDFLGK 972
            +KD  KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP PP+ILK DFLGK
Sbjct: 600  SKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPKPPSILKFDFLGK 659

Query: 971  DSIRYQNEVEVEIPVFKAIQQFRSGKEGSDNLFDKLDTTKLNAHLKELMPGLSAKVFRTY 792
            DSIRYQNEVEVE+PV+KAIQQFR+GK G D+LFDKLDT+KLNAHLK LMPGL+AKVFRTY
Sbjct: 660  DSIRYQNEVEVELPVYKAIQQFRTGKRGGDDLFDKLDTSKLNAHLKGLMPGLTAKVFRTY 719

Query: 791  NASITLDDMLNKETKGGDVSQKVAVYQHANKEVAIICNHQRTVSKSHSTQMLRXXXXXXX 612
            NASITLD+ML++ETKGG+V++K+ VYQHANKEVAIICNHQRTVSKSH  QM R       
Sbjct: 720  NASITLDEMLSRETKGGNVAEKIVVYQHANKEVAIICNHQRTVSKSHPAQMTRLNGKIDE 779

Query: 611  XXXXXXXXXXXLSRAKKGKPPLKGSDGKTKRNMNPEALEKKIAQTNTKIEKMERDKEIKE 432
                       L+RAKKGKPPL+ +DGK KRN+ PEALE+KI QTN KIEKMERDKE KE
Sbjct: 780  LKGILDGLQTDLARAKKGKPPLEDADGKPKRNLTPEALERKIGQTNAKIEKMERDKETKE 839

Query: 431  DLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMFNKSLLAKFAWAMDVEPSFRF 267
             LKT+ALGTSKI+YLDPRITVAWCKR+EVPIEK+FNKSLLAKFAW+MDV+PSFRF
Sbjct: 840  GLKTIALGTSKISYLDPRITVAWCKRHEVPIEKVFNKSLLAKFAWSMDVDPSFRF 894


>BAK32960.1 topoisomerase I [Ophiorrhiza pseudofasciculata]
          Length = 925

 Score = 1045 bits (2701), Expect = 0.0
 Identities = 573/920 (62%), Positives = 641/920 (69%), Gaps = 28/920 (3%)
 Frame = -2

Query: 2942 DSEDDR-PLVFKRSTPLVKHNQVKPDVKKTSMQKPDGKSGRQMSDVRSPNGNGNGQDSNI 2766
            D EDD  P++FKRS P  K NQ   + KK S+QK DG+S    SDVR      NG+ S+ 
Sbjct: 13   DMEDDGGPVIFKRSKPAPKQNQANSEKKKLSLQKQDGQSAVHTSDVRP----ANGESSSA 68

Query: 2765 QKGKTGPSTKGXXXXXXXXXXXXXXXXXXXXXXXXPLASTKASTSGADRSRQNIQQNKTA 2586
            QKG+  PS K                         P A++K S S    ++Q      +A
Sbjct: 69   QKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAKQQNHHKSSA 128

Query: 2585 TVKVDKPS-GXXXXXXXXXXXXXXXPLNSRLPVGGSKGSISVVNKRPGSSGPASLAKPDP 2409
                 KPS                 PL++R     SKG  +  NK  G S   S+ +P  
Sbjct: 129  AFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDS--CSIRRPVI 186

Query: 2408 GVKEEDSEDDIPLSHKFKQKSNAGES-SNANDSDVK-PFASKHQQNGTSARDNVKNPSPG 2235
              + EDSED+ PLS +F  KS+ GES S + DSD K P A+K QQNG+++RD   N S  
Sbjct: 187  E-ESEDSEDEKPLSCRFTSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGPMNKSAS 245

Query: 2234 L-NKRPSAEVKCSGQSPVKKAKHAAASTPVNGKKVSVKAEPKKEXXXXXXDYAT------ 2076
            L NKRP  E K   QS VKK K ++  T ++ K+ +VK EPK E        +       
Sbjct: 246  LSNKRPPGEAKSLNQSSVKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQ 305

Query: 2075 ---------------ISQRLKK-PVTPIXXXXXXXXXXXXXXXXXXXXXXXXXKITKSTQ 1944
                           ISQR+KK P +                           K+ K T 
Sbjct: 306  SATSKPKDDDDDNVPISQRIKKSPASVSKSSVPVKKASTVVSSSLKKVNKNSKKVIKKTA 365

Query: 1943 FSKSLNVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAV 1764
            ++KS  VPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYK +P+ LTPEQEEVATM AV
Sbjct: 366  YTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEVATMFAV 425

Query: 1763 MQDTDYMTKPVFRENVMNDWKKILGRNHIIKNLDDCDFTPIYEWHQSEKEKKKQMSAXXX 1584
            M DTDYM KP F+EN  +DWKKILG+NH+I+NL+DCDF PIYEWHQ EKEKKKQM+    
Sbjct: 426  MLDTDYMNKPCFKENFFSDWKKILGKNHMIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEK 485

Query: 1583 XXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITI 1404
                        KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI P DITI
Sbjct: 486  KALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDITI 545

Query: 1403 NIGKDAPIPECPIPGESWKEVRHDNTVTWLAYWLDPINGKEFKYVFLAASSSLKGQSDKE 1224
            NIGKDAPIPECPIPGE WKEVR+ NTVTWLAYW DPIN KEFKYVFLAASS+LKGQSDKE
Sbjct: 546  NIGKDAPIPECPIPGERWKEVRNGNTVTWLAYWNDPINQKEFKYVFLAASSTLKGQSDKE 605

Query: 1223 KYEKARKLKGYIAGIRTAYTKDFAN-KDTAKRQIAVATYLIDKLALRAGNEKDDDEADTV 1047
            KYEKAR LK YI GIR AYTKDF N KD  K+QIAVATYLIDKLALRAGNEKDDDEADTV
Sbjct: 606  KYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTV 665

Query: 1046 GCCTLKVENVEPSPPNILKLDFLGKDSIRYQNEVEVEIPVFKAIQQFRSGKEGSDNLFDK 867
            GCCTLKVENVEP PPNILK DFLGKDSIRYQNEV+VE  VFKAIQQFRSGKEGS++LFD+
Sbjct: 666  GCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDR 725

Query: 866  LDTTKLNAHLKELMPGLSAKVFRTYNASITLDDMLNKETKGGDVSQKVAVYQHANKEVAI 687
            LDT+KLNAHLKELMPGL+AKVFRTYNASITLDDML+KETKGG+V++ V VYQHANKEVAI
Sbjct: 726  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEVAENVVVYQHANKEVAI 785

Query: 686  ICNHQRTVSKSHSTQMLRXXXXXXXXXXXXXXXXXXLSRAKKGKPPLKGSDGKTKRNMNP 507
            ICNHQRTVSKSHS QM R                  LSRAKKGKPP KG+DGK KRN+NP
Sbjct: 786  ICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPTKGADGKAKRNLNP 845

Query: 506  EALEKKIAQTNTKIEKMERDKEIKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMF 327
            EALE+KI QTN KIEKMERDKE KEDLKTVALGTSKINYLDPRITVAWCKR+EVPIEK+F
Sbjct: 846  EALERKITQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 905

Query: 326  NKSLLAKFAWAMDVEPSFRF 267
            NKSLLAKFAW+MDV+PSFRF
Sbjct: 906  NKSLLAKFAWSMDVDPSFRF 925


>CDP13767.1 unnamed protein product [Coffea canephora]
          Length = 926

 Score = 1042 bits (2694), Expect = 0.0
 Identities = 565/918 (61%), Positives = 639/918 (69%), Gaps = 28/918 (3%)
 Frame = -2

Query: 2936 EDDRPLVFKRSTPLVKHNQVKPDVKKTSMQKPDGKSGRQMSDVRSPNGNGNGQDSNIQKG 2757
            E++ PLVFKR++   K N    + KK S QK DG+S R  SDV   NG    Q S+ Q G
Sbjct: 17   EENAPLVFKRTSSSSKQNLSNSETKKLSSQKRDGQSSRNSSDVCPVNG----QSSSAQTG 72

Query: 2756 KTGPSTKGXXXXXXXXXXXXXXXXXXXXXXXXPLASTKASTSGADRSRQNIQQNKTATVK 2577
            +   S K                         P A++K S+S +   +Q      +  VK
Sbjct: 73   RVVSSAKTPPAKSPLSSPKAANISAKTSLITSPGANSKPSSSTSATVKQLENHKNSPVVK 132

Query: 2576 VDKPS-GXXXXXXXXXXXXXXXPLNSRLPVGGSKGSISVVNKRPGSSGPASLAKPDPGVK 2400
            + K S                 PL ++LP G S+  ++  NK     G  S     PGV+
Sbjct: 133  LPKRSVSAAKLSSTPEDSDDDKPLMAKLPSGSSRAIVNHGNK----DGDGSSLVQKPGVE 188

Query: 2399 E-EDSEDDIPLSHKFKQKSNAGES--SNANDSDVKPFASKHQQNGTSARDNVKNPSPGL- 2232
            E EDS+D+ PLS ++  KSN  ES   + N  + K   +K QQNG++ RD     S  L 
Sbjct: 189  EDEDSDDEKPLSSRYLSKSNLVESISKSRNPGEKKSLPAKVQQNGSALRDGPVGKSSSLS 248

Query: 2231 NKRPSAEVKCSGQSPVKKAKHAAASTPVNGKKVSVKAEPKKEXXXXXXD----------- 2085
            NKRP  EVK S +S VKK K +  +  +N K+ ++KAEPK E                  
Sbjct: 249  NKRPPGEVKSSDESAVKKPKLSGPTAAINKKQATLKAEPKVEDDDDDILISQTAKKMFAS 308

Query: 2084 ------------YATISQRLKKPVTPIXXXXXXXXXXXXXXXXXXXXXXXXXKITKSTQF 1941
                        +  I+QR+KK  T +                         KI K +++
Sbjct: 309  ASKPKSNDDDDDHVPITQRMKKSTTSVSQSSSVKKVAKVVSSSLKKTNKKSKKIIKKSKY 368

Query: 1940 SKSLNVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAVM 1761
            SKS  VPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKG+PV LTPEQEEVATM AVM
Sbjct: 369  SKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGQPVTLTPEQEEVATMFAVM 428

Query: 1760 QDTDYMTKPVFRENVMNDWKKILGRNHIIKNLDDCDFTPIYEWHQSEKEKKKQMSAXXXX 1581
             DTDYM+KP F+EN  +DWK+ILG+NH I+NL+DCDF PIYEWHQ EKEKKKQM+     
Sbjct: 429  LDTDYMSKPQFKENFFSDWKRILGKNHTIQNLEDCDFRPIYEWHQKEKEKKKQMTTEEKK 488

Query: 1580 XXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITIN 1401
                       KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI P DITIN
Sbjct: 489  SLKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDITIN 548

Query: 1400 IGKDAPIPECPIPGESWKEVRHDNTVTWLAYWLDPINGKEFKYVFLAASSSLKGQSDKEK 1221
            IGKDAPIPECPIPGE WKE+RHDNTVTWLA+W DPIN KEFKYVFLAASS+LKGQSDKEK
Sbjct: 549  IGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGQSDKEK 608

Query: 1220 YEKARKLKGYIAGIRTAYTKDFANKDTAKRQIAVATYLIDKLALRAGNEKDDDEADTVGC 1041
            YEKAR LK YI GIRTAYTKDFA+KD  K+QIAVATYLIDKLALRAGNEKDDDEADTVGC
Sbjct: 609  YEKARLLKDYIHGIRTAYTKDFASKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTVGC 668

Query: 1040 CTLKVENVEPSPPNILKLDFLGKDSIRYQNEVEVEIPVFKAIQQFRSGKEGSDNLFDKLD 861
            CTLKVENVEP PPNILK DFLGKDSIRYQNEVEVE  VFKAIQQFRSGKEGS++LFDKLD
Sbjct: 669  CTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVESGVFKAIQQFRSGKEGSEDLFDKLD 728

Query: 860  TTKLNAHLKELMPGLSAKVFRTYNASITLDDMLNKETKGGDVSQKVAVYQHANKEVAIIC 681
            T+KLNAHLKELMPGL+AKVFRTYNASITLDDML+++T GGDV +KV VYQ ANKEVAIIC
Sbjct: 729  TSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRKTNGGDVLEKVVVYQQANKEVAIIC 788

Query: 680  NHQRTVSKSHSTQMLRXXXXXXXXXXXXXXXXXXLSRAKKGKPPLKGSDGKTKRNMNPEA 501
            NHQRTVSK+HS QM R                  LSRAKKGKPPLK +DGK KRN+NPEA
Sbjct: 789  NHQRTVSKTHSAQMSRLNEKIEELKGVLEELKTDLSRAKKGKPPLKNADGKPKRNLNPEA 848

Query: 500  LEKKIAQTNTKIEKMERDKEIKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMFNK 321
            LE+KIAQTN KIEKMERDKE KEDLKTVALGTSKINYLDPRITVAWCKR+EVPIEK+FNK
Sbjct: 849  LERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNK 908

Query: 320  SLLAKFAWAMDVEPSFRF 267
            SLLAKFAW+MDV+PSFRF
Sbjct: 909  SLLAKFAWSMDVDPSFRF 926


>BAG31377.1 topoisomerase I [Catharanthus roseus]
          Length = 910

 Score = 1037 bits (2681), Expect = 0.0
 Identities = 558/908 (61%), Positives = 631/908 (69%), Gaps = 18/908 (1%)
 Frame = -2

Query: 2936 EDDRPLVFKRSTPLVKHNQVKPDVKKTSMQKPDGKSGRQMSDVRSPNGNGNG-------- 2781
            EDD P+VFKR+    K +Q   + +K S QK DG+S RQ+ D R  NG  +         
Sbjct: 17   EDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDSRPANGESSSGQKGRMVP 76

Query: 2780 --QDSNIQKGKTGPSTKGXXXXXXXXXXXXXXXXXXXXXXXXPLASTKASTSGADRSRQN 2607
              + S ++   + P +K                           A++K STSG+ + +  
Sbjct: 77   PSKPSQVKSPLSSPPSKPSQVKSPLSSPKVSTSSAKKSPVSSLPANSKPSTSGSFKVKPF 136

Query: 2606 IQQNKTATVKVDKPSGXXXXXXXXXXXXXXXP---LNSRLPVGGSKGSISVVNKRPGSSG 2436
             Q      +K +K S                    L+ R     SKG+ + V+K      
Sbjct: 137  NQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSASSSKGNTNQVSKEG---- 192

Query: 2435 PASLAKPDPGVKEEDSEDDIPLSHKFKQKSNAGES-SNANDSDV-KPFASKHQQNGTSAR 2262
                +KP+     EDS+D+ PLS +F  KS  GES S A DSD  KP A K Q NG++ R
Sbjct: 193  ----SKPE----NEDSDDEKPLSSRFPLKSGVGESTSKAYDSDDDKPLAKKLQHNGSAMR 244

Query: 2261 DNVKNPSPGL-NKRPSAEVKCSGQSPVKKAKHAAASTPVNGKKVSVKAEPKKEXXXXXXD 2085
            D   N    + NKRP  ++K S Q  VKK K ++ + P N K+ SVK EPK E       
Sbjct: 245  DGQPNKYSNMSNKRPPGDIKSSNQLSVKKPKLSSVTAPTNKKQASVKPEPKAEDDDDD-- 302

Query: 2084 YATISQRLKKPVTPIXXXXXXXXXXXXXXXXXXXXXXXXXKITKSTQFSKSLNVPPGSGE 1905
            +  ISQR+KK  T                           K+ K++++SKS  VPP SGE
Sbjct: 303  HLPISQRIKKSPTSESKSSSIKKTTKVVSSSVKKVNKKSKKVMKNSKYSKSSKVPPSSGE 362

Query: 1904 GQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAVMQDTDYMTKPVFR 1725
            G+KW  L HNGVIFPPPYKPHG+KMLYKGKPVDLTPEQEEVATM AVM DTDYM KP F+
Sbjct: 363  GKKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMNKPRFK 422

Query: 1724 ENVMNDWKKILGRNHIIKNLDDCDFTPIYEWHQSEKEKKKQMSAXXXXXXXXXXXXXXXK 1545
            EN   DWKKILG+NH+I+NL++CDF+PIYEWHQSEKEKKKQM+                K
Sbjct: 423  ENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSEKEKKKQMTTEEKKALKEEKLKQEEK 482

Query: 1544 YMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITINIGKDAPIPECPI 1365
            YMWA VDG KEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI P DITINIGKDAPIPECP+
Sbjct: 483  YMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCDITINIGKDAPIPECPV 542

Query: 1364 PGESWKEVRHDNTVTWLAYWLDPINGKEFKYVFLAASSSLKGQSDKEKYEKARKLKGYIA 1185
            PGE WKEVRHDNTVTWLA+W DPIN KEFKYVFLAASS+LKG SDKEKYEKAR LK YI 
Sbjct: 543  PGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGLSDKEKYEKARLLKDYIQ 602

Query: 1184 GIRTAYTKDFANKDTAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPSP 1005
            GIR AYTKDFA+KD  K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP P
Sbjct: 603  GIRAAYTKDFASKDPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVP 662

Query: 1004 PNILKLDFLGKDSIRYQNEVEVEIPVFKAIQQFRSGKEGSDNLFDKLDTTKLNAHLKELM 825
            PNILK DFLGKDSIRYQNEVEVE  VFKAIQQFRSGKEGS +LFD LDT+KLNAHLKELM
Sbjct: 663  PNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSSDLFDLLDTSKLNAHLKELM 722

Query: 824  PGLSAKVFRTYNASITLDDMLNKETKGGDVSQKVAVYQHANKEVAIICNHQRTVSKSHST 645
            PGL+AKVFRTYNASITLDDML++ETKGGDV++KV VYQHANKEVAIICNHQRTVSKSHS 
Sbjct: 723  PGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSA 782

Query: 644  QMLRXXXXXXXXXXXXXXXXXXLSRAKKGKPPL--KGSDGKTKRNMNPEALEKKIAQTNT 471
            QMLR                  LSR KKGKPPL  K +DGK KRN+NPE+LEKKIAQTN 
Sbjct: 783  QMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPKRNLNPESLEKKIAQTNA 842

Query: 470  KIEKMERDKEIKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMFNKSLLAKFAWAM 291
            KIEKMERDKE KEDLKTVALGTSKINYLDPRITVAWCKR+EVPIEK+FNKSLLAKF WAM
Sbjct: 843  KIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM 902

Query: 290  DVEPSFRF 267
            DV+PSFRF
Sbjct: 903  DVDPSFRF 910


>BAG31375.1 topoisomerase I [Ophiorrhiza japonica]
          Length = 927

 Score = 1031 bits (2667), Expect = 0.0
 Identities = 565/922 (61%), Positives = 637/922 (69%), Gaps = 30/922 (3%)
 Frame = -2

Query: 2942 DSEDDR-PLVFKRSTPLVKHNQVKPDVKKTSMQKPDGKSGRQMSDVRSPNGNGNGQDSNI 2766
            D EDD  P++FKRS P  K NQ   + KK S+QK  G+S    SDVR      NG+ S+ 
Sbjct: 13   DMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVRP----ANGESSSA 68

Query: 2765 QKGKTGPSTKGXXXXXXXXXXXXXXXXXXXXXXXXPLASTKASTSGADRSRQNIQQNKTA 2586
            QKG+  PS K                         P A++K S S    ++Q      +A
Sbjct: 69   QKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAKQQNHHKSSA 128

Query: 2585 TVKVDKPS-GXXXXXXXXXXXXXXXPLNSRLPVGGSKGSISVVNKRPGSSGPASLAKPDP 2409
                 KPS                 PL++R     SKG  +  NK  G S        + 
Sbjct: 129  AFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSCSIRRRVIE- 187

Query: 2408 GVKEEDSEDDIPLSHKFKQKSNAGES-SNANDSDVK-PFASKHQQNGTSARDNVKNPSPG 2235
              + EDSED+ PLS +F  KS+ GES S + DSD K P A+K QQNG+ +RD   N S  
Sbjct: 188  --ESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQQNGSVSRDGPMNKSAS 245

Query: 2234 L-NKRPSAEVKCSGQSPVKKAKHAAASTPVNGKKVSVKAEPKKEXXXXXXDY-------- 2082
            L NKRP  EVK   QS VKK K ++  T ++ K+ +VK EP+ +      +         
Sbjct: 246  LSNKRPPGEVKSLNQSSVKKPKLSSPITSISNKQAAVKPEPEPKAEDDDDNIPLSQRGKK 305

Query: 2081 ---------------ATISQRLKK-PVTPIXXXXXXXXXXXXXXXXXXXXXXXXXKITKS 1950
                             I+QR+KK P +                           K+ K 
Sbjct: 306  SQAATSKPKDEDDDNVPIAQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKNSKKVIKK 365

Query: 1949 TQFSKSLNVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMI 1770
            T ++KS  VPPGSGEGQKWTTLVHNGVIFPPPY PHGVKMLYK +P+ LTPEQEEVATM 
Sbjct: 366  TAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYNPHGVKMLYKRQPITLTPEQEEVATMF 425

Query: 1769 AVMQDTDYMTKPVFRENVMNDWKKILGRNHIIKNLDDCDFTPIYEWHQSEKEKKKQMSAX 1590
            AVM DTDYM KP F+EN  +DWKK+LG+NH I+NL+DCDF PIYEWHQ EKEKKKQM+  
Sbjct: 426  AVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQMTTE 485

Query: 1589 XXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDI 1410
                          KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI P DI
Sbjct: 486  EKKALKEDKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDI 545

Query: 1409 TINIGKDAPIPECPIPGESWKEVRHDNTVTWLAYWLDPINGKEFKYVFLAASSSLKGQSD 1230
            TINIGKDAPIPECPIPGE WKEVR+DNTVTWLA+W+DPIN KEFKYVFLAASS+LKGQSD
Sbjct: 546  TINIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWIDPINQKEFKYVFLAASSTLKGQSD 605

Query: 1229 KEKYEKARKLKGYIAGIRTAYTKDFAN-KDTAKRQIAVATYLIDKLALRAGNEKDDDEAD 1053
            KEKYEKAR LK YI GIR AYTKDF N KD  K+QIAVATYLIDKLALRAGNEKDDDEAD
Sbjct: 606  KEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEAD 665

Query: 1052 TVGCCTLKVENVEPSPPNILKLDFLGKDSIRYQNEVEVEIPVFKAIQQFRSGKEGSDNLF 873
            TVGCCTLKVENVEP PPNILK DFLGKDSIRYQNEV+VE  VFKAIQQFRSGKEGS++LF
Sbjct: 666  TVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLF 725

Query: 872  DKLDTTKLNAHLKELMPGLSAKVFRTYNASITLDDMLNKETKGGDVSQKVAVYQHANKEV 693
            D+LDT+KLNAHLKELMPGL+AKVFRTYNASITLDDML+KETKGG+V++KV VYQHANKEV
Sbjct: 726  DRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEVAEKVVVYQHANKEV 785

Query: 692  AIICNHQRTVSKSHSTQMLRXXXXXXXXXXXXXXXXXXLSRAKKGKPPLKGSDGKTKRNM 513
            AIICNHQRTVSKSHS QM R                  LSR KKGKPP KG+DGK KRN+
Sbjct: 786  AIICNHQRTVSKSHSAQMSRLNEKIDELKTAMEELKTDLSRVKKGKPPSKGADGKPKRNL 845

Query: 512  NPEALEKKIAQTNTKIEKMERDKEIKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEK 333
            NPEALE+K+AQ N KIEKMERDKE KEDLKTVALGTSKINYLDPRITVAWCKR+EVPIEK
Sbjct: 846  NPEALERKMAQINAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEK 905

Query: 332  MFNKSLLAKFAWAMDVEPSFRF 267
            +FNKSLLAKFAW+MDV+PSFRF
Sbjct: 906  IFNKSLLAKFAWSMDVDPSFRF 927


>BAK32956.1 topoisomerase I [Ophiorrhiza fucosa]
          Length = 926

 Score = 1025 bits (2651), Expect = 0.0
 Identities = 564/920 (61%), Positives = 635/920 (69%), Gaps = 28/920 (3%)
 Frame = -2

Query: 2942 DSEDDR-PLVFKRSTPLVKHNQVKPDVKKTSMQKPDGKSGRQMSDVRSPNGNGNGQDSNI 2766
            D EDD  P++FKRS P  K NQ   + KK S+QK  G+S    SDVR      NG+ S+ 
Sbjct: 14   DMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVRP----ANGESSSA 69

Query: 2765 QKGKTGPSTKGXXXXXXXXXXXXXXXXXXXXXXXXPLASTKASTSGADRSRQNIQQNKTA 2586
            QKG+  PS +                         P A++K S S    ++Q      +A
Sbjct: 70   QKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAKQQNHHKSSA 129

Query: 2585 TVKVDKPS-GXXXXXXXXXXXXXXXPLNSRLPVGGSKGSISVVNKRPGSSGPASLAKPDP 2409
                 KPS                 PL +R     SKG  +  NK  G S   S+ +P  
Sbjct: 130  AFIEPKPSVPPAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDS--CSIRRPVV 187

Query: 2408 GVKEEDSEDDIPLSHKFKQKSNAGES-SNANDSDVK-PFASKHQQNGTSARDNVKNPSPG 2235
              + EDSED+ PLS +F  KS+ GES S + DSD K P A+K QQNG+++RD   N S  
Sbjct: 188  E-ESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGPMNKSAS 246

Query: 2234 L-NKRPSAEVKCSGQSPVKKAKHAAASTPVNGKKVSVKAEPKKEXXXXXXDY-------- 2082
            L NKR   EVK   QS +KK K ++  T ++ K+ +VK EPK E                
Sbjct: 247  LSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQ 306

Query: 2081 -------------ATISQRLKK-PVTPIXXXXXXXXXXXXXXXXXXXXXXXXXKITKSTQ 1944
                         A ISQR+KK P +                           K+ K T 
Sbjct: 307  TAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTA 366

Query: 1943 FSKSLNVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAV 1764
            ++KS  VPPGSGEGQKWTTLVHNGV+FPPPYKPHGVKMLYK +P+ LTPEQEEVATM A 
Sbjct: 367  YTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQEEVATMFAA 426

Query: 1763 MQDTDYMTKPVFRENVMNDWKKILGRNHIIKNLDDCDFTPIYEWHQSEKEKKKQMSAXXX 1584
            M DTDYM KP F+EN  +DWKKILG+NH I+NL+DCDF PIYEWHQ E+EKKKQM+    
Sbjct: 427  MLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEREKKKQMTTEEK 486

Query: 1583 XXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITI 1404
                        KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRIHP DITI
Sbjct: 487  KALKDERLQLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIHPRDITI 546

Query: 1403 NIGKDAPIPECPIPGESWKEVRHDNTVTWLAYWLDPINGKEFKYVFLAASSSLKGQSDKE 1224
            NIGKDAPIPECPIPGE WKEVR+DNTVTWLAYW DP+N KE KYVFLA SS+LKGQSDKE
Sbjct: 547  NIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPSSTLKGQSDKE 606

Query: 1223 KYEKARKLKGYIAGIRTAYTKDFAN-KDTAKRQIAVATYLIDKLALRAGNEKDDDEADTV 1047
            KYEKAR LK YI GIR AYTKDF N KD  K+QIAVATYLIDKLALRAGNEKDDDEADTV
Sbjct: 607  KYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTV 666

Query: 1046 GCCTLKVENVEPSPPNILKLDFLGKDSIRYQNEVEVEIPVFKAIQQFRSGKEGSDNLFDK 867
            GCCTLKVENVEP PPNILK+DF+GKDSIRYQNEV+VE  VFKAIQQFRSGKEGS++LFD+
Sbjct: 667  GCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDR 726

Query: 866  LDTTKLNAHLKELMPGLSAKVFRTYNASITLDDMLNKETKGGDVSQKVAVYQHANKEVAI 687
            LDT+KLNAHLKELMPGL+AKVFRTYNASITLDDML+KETKGG V++KV VYQHANKEVAI
Sbjct: 727  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHANKEVAI 786

Query: 686  ICNHQRTVSKSHSTQMLRXXXXXXXXXXXXXXXXXXLSRAKKGKPPLKGSDGKTKRNMNP 507
            ICNHQRTVSKSHS QM R                  LSRAKKGKPP KG DG+ KRN+NP
Sbjct: 787  ICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGEPKRNLNP 846

Query: 506  EALEKKIAQTNTKIEKMERDKEIKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMF 327
            EALE+KIAQTN KIEKMERDK+ KEDLK VAL TSKI+YLDPRITVAWCKR EVPIEKMF
Sbjct: 847  EALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEVPIEKMF 906

Query: 326  NKSLLAKFAWAMDVEPSFRF 267
            NKSLLAKFAWAMDV+PSFRF
Sbjct: 907  NKSLLAKFAWAMDVDPSFRF 926


>BAG31373.1 topoisomerase I [Ophiorrhiza pumila]
          Length = 926

 Score = 1023 bits (2645), Expect = 0.0
 Identities = 563/920 (61%), Positives = 635/920 (69%), Gaps = 28/920 (3%)
 Frame = -2

Query: 2942 DSEDDR-PLVFKRSTPLVKHNQVKPDVKKTSMQKPDGKSGRQMSDVRSPNGNGNGQDSNI 2766
            D EDD  P++FKRS P  K NQ   + KK S+QK  G+S    SDVR      NG+ S+ 
Sbjct: 14   DMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVRP----ANGESSSA 69

Query: 2765 QKGKTGPSTKGXXXXXXXXXXXXXXXXXXXXXXXXPLASTKASTSGADRSRQNIQQNKTA 2586
            QKG+  PS +                         P A++K S S    ++Q      +A
Sbjct: 70   QKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAKQQNHHKSSA 129

Query: 2585 TVKVDKPS-GXXXXXXXXXXXXXXXPLNSRLPVGGSKGSISVVNKRPGSSGPASLAKPDP 2409
                 KPS                 PL +R     SKG  +  NK  G S   S+ +P  
Sbjct: 130  AFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDS--CSIRRPVI 187

Query: 2408 GVKEEDSEDDIPLSHKFKQKSNAGES-SNANDSDVK-PFASKHQQNGTSARDNVKNPSPG 2235
              + EDSED+ PLS +F  KS+ GES S ++DSD K P A+K QQNG+++RD   N S  
Sbjct: 188  E-ESEDSEDEKPLSRRFPSKSSLGESTSKSHDSDEKKPLAAKVQQNGSASRDGPMNKSAS 246

Query: 2234 L-NKRPSAEVKCSGQSPVKKAKHAAASTPVNGKKVSVKAEPKKEXXXXXXDY-------- 2082
            L NKR   EVK   QS +KK K ++  T ++ K+ +VK EPK E                
Sbjct: 247  LSNKRAPGEVKSLNQSSLKKPKLSSTITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQ 306

Query: 2081 -------------ATISQRLKK-PVTPIXXXXXXXXXXXXXXXXXXXXXXXXXKITKSTQ 1944
                         A ISQR+KK P +                           K+ K T 
Sbjct: 307  TAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTA 366

Query: 1943 FSKSLNVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAV 1764
            ++KS  VPPGSGEGQKWTTLVHNGV+FPPPYKPHGVKMLYK +P+ LTPEQEEVATM A 
Sbjct: 367  YTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQEEVATMFAA 426

Query: 1763 MQDTDYMTKPVFRENVMNDWKKILGRNHIIKNLDDCDFTPIYEWHQSEKEKKKQMSAXXX 1584
            M DTDYM KP F+EN  +DWKKILG+NH I+NL+DCDF PIYEWHQ EKEKKKQM+    
Sbjct: 427  MLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEK 486

Query: 1583 XXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITI 1404
                        KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI P DITI
Sbjct: 487  KALKEERLQLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIRPRDITI 546

Query: 1403 NIGKDAPIPECPIPGESWKEVRHDNTVTWLAYWLDPINGKEFKYVFLAASSSLKGQSDKE 1224
            NIGKDAPIPECPIPGE WKEVR+DNTVTWLAYW DP+N KE KYVFLAASS+LKGQSDKE
Sbjct: 547  NIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAASSTLKGQSDKE 606

Query: 1223 KYEKARKLKGYIAGIRTAYTKDFAN-KDTAKRQIAVATYLIDKLALRAGNEKDDDEADTV 1047
            KYEKAR LK YI GIR AYTKDF N KD  K+Q+AVATYLIDKLALRAGNEKDDDEADTV
Sbjct: 607  KYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQVAVATYLIDKLALRAGNEKDDDEADTV 666

Query: 1046 GCCTLKVENVEPSPPNILKLDFLGKDSIRYQNEVEVEIPVFKAIQQFRSGKEGSDNLFDK 867
            GCCTLKVENVEP PPNILK+DF+GKDSIRYQNEV+VE  VFKAIQQFRSGKEGS++LFD+
Sbjct: 667  GCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDR 726

Query: 866  LDTTKLNAHLKELMPGLSAKVFRTYNASITLDDMLNKETKGGDVSQKVAVYQHANKEVAI 687
            LDT+KLNAHLKELMPGL+AKVFRTYNASITLDDML+KETKGG V++KV VYQ ANKEVAI
Sbjct: 727  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQRANKEVAI 786

Query: 686  ICNHQRTVSKSHSTQMLRXXXXXXXXXXXXXXXXXXLSRAKKGKPPLKGSDGKTKRNMNP 507
            ICNHQRTVSKSHS QM R                  LSRAKKGKPP KG DG+ KRN+NP
Sbjct: 787  ICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGEPKRNLNP 846

Query: 506  EALEKKIAQTNTKIEKMERDKEIKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMF 327
            EALE+KIAQTN KIEKMERDK+ KEDLK VAL TSKI+YLDPRITVAWCKR EVPIEKMF
Sbjct: 847  EALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEVPIEKMF 906

Query: 326  NKSLLAKFAWAMDVEPSFRF 267
            NKSLLAKFAWAMDV+PSFRF
Sbjct: 907  NKSLLAKFAWAMDVDPSFRF 926


>BAK32962.1 topoisomerase I [Ophiorrhiza trichocarpon var. glabra]
          Length = 920

 Score = 1022 bits (2643), Expect = 0.0
 Identities = 562/913 (61%), Positives = 634/913 (69%), Gaps = 28/913 (3%)
 Frame = -2

Query: 2942 DSEDDR-PLVFKRSTPLVKHNQVKPDVKKTSMQKPDGKSGRQMSDVRSPNGNGNGQDSNI 2766
            D EDD  P++FKRS P  K NQ   + KK S+Q+  G+S    SDVR      NG++S+ 
Sbjct: 14   DMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQRHVGQSAVHTSDVRP----ANGENSSA 69

Query: 2765 QKGKTGPSTKGXXXXXXXXXXXXXXXXXXXXXXXXPLASTKASTSGADRSRQNIQQNKTA 2586
            QKG+  PS K                           A++K S S    ++Q      +A
Sbjct: 70   QKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSAGANSKPSASATSTAKQQNHHKSSA 129

Query: 2585 TVKVDKPS-GXXXXXXXXXXXXXXXPLNSRLPVGGSKGSISVVNKRPGSSGPASLAKPDP 2409
                 KPS                 PL++R     SKG  +  NK  G S   S+ +P  
Sbjct: 130  AFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDS--CSIRRPVI 187

Query: 2408 GVKEEDSEDDIPLSHKFKQKSNAGES-SNANDSDVK-PFASKHQQNGTSARDNVKNPSPG 2235
              + EDSED+ PLS +F  KS+ GES S + DSD K P A+K Q NG+++RD+  N S  
Sbjct: 188  E-ESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQPNGSASRDSPMNKSAS 246

Query: 2234 L-NKRPSAEVKCSGQSPVKKAKHAAASTPVNGKKVSVKAEPKKEXXXXXXDYAT------ 2076
            L NKRP  EVK   QS +KK K ++  T ++ K+ +VK EPK E        +       
Sbjct: 247  LSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQ 306

Query: 2075 ---------------ISQRLKK-PVTPIXXXXXXXXXXXXXXXXXXXXXXXXXKITKSTQ 1944
                           ISQR+KK P +                           K+ K T 
Sbjct: 307  TATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTA 366

Query: 1943 FSKSLNVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAV 1764
            ++KS  VPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYK +P+ LTPEQEEVATM AV
Sbjct: 367  YTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEVATMFAV 426

Query: 1763 MQDTDYMTKPVFRENVMNDWKKILGRNHIIKNLDDCDFTPIYEWHQSEKEKKKQMSAXXX 1584
            M DTDYM KP F+EN  +DWKK+LG+NH I+NL+DCDF PIYEWHQ EKEKKKQM+    
Sbjct: 427  MLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEK 486

Query: 1583 XXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITI 1404
                        KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI P DITI
Sbjct: 487  KALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDITI 546

Query: 1403 NIGKDAPIPECPIPGESWKEVRHDNTVTWLAYWLDPINGKEFKYVFLAASSSLKGQSDKE 1224
            NIGKDAPIPECPIPGE WKEVR+DNTVTWLAYW DPIN KEFKYVFLAASS+LKGQSDKE
Sbjct: 547  NIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAASSTLKGQSDKE 606

Query: 1223 KYEKARKLKGYIAGIRTAYTKDFAN-KDTAKRQIAVATYLIDKLALRAGNEKDDDEADTV 1047
            KYEKAR LK YI GIR AYTKDF N KD  K+QIAVATYLIDKLALRAGNEKDDDEADTV
Sbjct: 607  KYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTV 666

Query: 1046 GCCTLKVENVEPSPPNILKLDFLGKDSIRYQNEVEVEIPVFKAIQQFRSGKEGSDNLFDK 867
            GCCTLKVENVEP PPNILK DFLGKDSIRYQNEV+VE  VFKAIQQFRSGKEGS++LFD+
Sbjct: 667  GCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDR 726

Query: 866  LDTTKLNAHLKELMPGLSAKVFRTYNASITLDDMLNKETKGGDVSQKVAVYQHANKEVAI 687
            LDT+KLNAHLKELMPGL+AKVFRTYNASITLDDML+K+T GG+V++KV VYQHANKEVAI
Sbjct: 727  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKKTNGGEVAEKVVVYQHANKEVAI 786

Query: 686  ICNHQRTVSKSHSTQMLRXXXXXXXXXXXXXXXXXXLSRAKKGKPPLKGSDGKTKRNMNP 507
            ICNHQRTVSKSHS QM R                  LSRAKKGKP  KG+DGK KRN+NP
Sbjct: 787  ICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPLSKGADGKPKRNLNP 846

Query: 506  EALEKKIAQTNTKIEKMERDKEIKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMF 327
            EALE+KIAQTN KIEKMERDKE KEDLKTVALGTSKINYLDPRITVAWCKR+EVPIEK+F
Sbjct: 847  EALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 906

Query: 326  NKSLLAKFAWAMD 288
            NKSLLAKFAWAM+
Sbjct: 907  NKSLLAKFAWAMN 919


>BAK32958.1 topoisomerase I [Ophiorrhiza pedunculata]
          Length = 920

 Score = 1021 bits (2641), Expect = 0.0
 Identities = 563/913 (61%), Positives = 634/913 (69%), Gaps = 28/913 (3%)
 Frame = -2

Query: 2942 DSEDDR-PLVFKRSTPLVKHNQVKPDVKKTSMQKPDGKSGRQMSDVRSPNGNGNGQDSNI 2766
            D EDD  P++FKRS P  K NQ   + KK S+QK  G+S    SDVR      NG++S+ 
Sbjct: 14   DMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVRP----ANGENSSA 69

Query: 2765 QKGKTGPSTKGXXXXXXXXXXXXXXXXXXXXXXXXPLASTKASTSGADRSRQNIQQNKTA 2586
            QKG+  PS K                         P A++K S S    ++Q      +A
Sbjct: 70   QKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAKQQNHHKSSA 129

Query: 2585 TVKVDKPS-GXXXXXXXXXXXXXXXPLNSRLPVGGSKGSISVVNKRPGSSGPASLAKPDP 2409
                 KPS                 PL++R     SKG  +  NK  G S   S+ +P  
Sbjct: 130  AFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDS--CSIRRPVI 187

Query: 2408 GVKEEDSEDDIPLSHKFKQKSNAGES-SNANDSDVK-PFASKHQQNGTSARDNVKNPSPG 2235
              + EDSED+ PLS +F  KS+ GES S + DSD K P A+K Q NG+++RD+  N S  
Sbjct: 188  E-ESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQPNGSASRDSPMNKSAS 246

Query: 2234 L-NKRPSAEVKCSGQSPVKKAKHAAASTPVNGKKVSVKAEPKKEXXXXXXDYAT------ 2076
            L NKRP  EVK   QS +KK K ++  T ++ K+ +VK EPK E        +       
Sbjct: 247  LSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQ 306

Query: 2075 ---------------ISQRLKK-PVTPIXXXXXXXXXXXXXXXXXXXXXXXXXKITKSTQ 1944
                           ISQR+KK P +                           K+ K T 
Sbjct: 307  TATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTA 366

Query: 1943 FSKSLNVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAV 1764
            ++KS  VPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYK +P+ LTPEQEEVATM AV
Sbjct: 367  YTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEVATMFAV 426

Query: 1763 MQDTDYMTKPVFRENVMNDWKKILGRNHIIKNLDDCDFTPIYEWHQSEKEKKKQMSAXXX 1584
            M DTDYM KP F+EN  +DWKK+LG+NH I+NL+DCDF PIYEWHQ EKEKKKQM+    
Sbjct: 427  MLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEK 486

Query: 1583 XXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITI 1404
                        KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI P DITI
Sbjct: 487  KALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDITI 546

Query: 1403 NIGKDAPIPECPIPGESWKEVRHDNTVTWLAYWLDPINGKEFKYVFLAASSSLKGQSDKE 1224
            NIGKDAPIPECPIPGE WKEVR+DNTVTWLAYW DPIN KEFKYVFLAASS+LKGQSDKE
Sbjct: 547  NIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAASSTLKGQSDKE 606

Query: 1223 KYEKARKLKGYIAGIRTAYTKDFAN-KDTAKRQIAVATYLIDKLALRAGNEKDDDEADTV 1047
            KYEKAR LK YI GIR AYTKDF N KD  K+QIAVATYLIDKLALRAGNEKDDDEADTV
Sbjct: 607  KYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTV 666

Query: 1046 GCCTLKVENVEPSPPNILKLDFLGKDSIRYQNEVEVEIPVFKAIQQFRSGKEGSDNLFDK 867
            GCCTLKVENVEP PPNILK DFLGKDSIRYQNEV+VE  VFKAI QFRSGKEGS++LFD+
Sbjct: 667  GCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIHQFRSGKEGSEDLFDR 726

Query: 866  LDTTKLNAHLKELMPGLSAKVFRTYNASITLDDMLNKETKGGDVSQKVAVYQHANKEVAI 687
            LDT+KLNAHLKELMPGL+AKVFRTYNASITLDDML+K+T GG+V++KV VYQHANKEVAI
Sbjct: 727  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKKTNGGEVAEKVVVYQHANKEVAI 786

Query: 686  ICNHQRTVSKSHSTQMLRXXXXXXXXXXXXXXXXXXLSRAKKGKPPLKGSDGKTKRNMNP 507
            ICNHQRTVSKSHS QM R                  LSRAKKGKP  KG+DGK KRN+NP
Sbjct: 787  ICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPLSKGADGKPKRNLNP 846

Query: 506  EALEKKIAQTNTKIEKMERDKEIKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMF 327
            EALE+KIAQTN KIEKMERDKE KEDLKTVALGTSKINYLDPRITVAWCKR+EVPIEK+F
Sbjct: 847  EALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 906

Query: 326  NKSLLAKFAWAMD 288
            NKSLLAKFAWAM+
Sbjct: 907  NKSLLAKFAWAMN 919


>BAG31374.1 topoisomerase I [Ophiorrhiza liukiuensis]
          Length = 926

 Score = 1020 bits (2637), Expect = 0.0
 Identities = 561/920 (60%), Positives = 637/920 (69%), Gaps = 28/920 (3%)
 Frame = -2

Query: 2942 DSEDDR-PLVFKRSTPLVKHNQVKPDVKKTSMQKPDGKSGRQMSDVRSPNGNGNGQDSNI 2766
            D EDD  P++FKRS P  K NQ   + KK S+QK  G+S    SDVR      NG+ S+ 
Sbjct: 14   DMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVRP----ANGESSSA 69

Query: 2765 QKGKTGPSTKGXXXXXXXXXXXXXXXXXXXXXXXXPLASTKASTSGADRSRQNIQQNKTA 2586
            QKG+  PS +                         P A++K S S    ++Q      +A
Sbjct: 70   QKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAKQQNHHKSSA 129

Query: 2585 TVKVDKPS-GXXXXXXXXXXXXXXXPLNSRLPVGGSKGSISVVNKRPGSSGPASLAKPDP 2409
                 KPS                 PL +R     SKG  +  NK  G S   S+ +P  
Sbjct: 130  AFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDS--CSIRRPVI 187

Query: 2408 GVKEEDSEDDIPLSHKFKQKSNAGES-SNANDSDVK-PFASKHQQNGTSARDNVKNPSPG 2235
              + EDSED+ PLS +F  KS+ GES S + DSD K P A+K QQNG+++RD   N S  
Sbjct: 188  E-ESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLATKVQQNGSASRDGPMNKSAS 246

Query: 2234 L-NKRPSAEVKCSGQSPVKKAKHAAASTPVNGKKVSVKAEPKKEXXXXXXDY-------- 2082
            L NKR   EVK   QS +KKAK ++  T ++ K+ +VK EPK E                
Sbjct: 247  LLNKRAPGEVKSLNQSSLKKAKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQ 306

Query: 2081 -------------ATISQRLKK-PVTPIXXXXXXXXXXXXXXXXXXXXXXXXXKITKSTQ 1944
                         A ISQR+KK P +                           K+ K T 
Sbjct: 307  TAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTA 366

Query: 1943 FSKSLNVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAV 1764
            ++KS  VPPGSGEGQKWTTLVHNGV+F PPYKPHGVKMLYK +P+ LTPEQEEVATM AV
Sbjct: 367  YTKSSKVPPGSGEGQKWTTLVHNGVMFLPPYKPHGVKMLYKXQPLTLTPEQEEVATMFAV 426

Query: 1763 MQDTDYMTKPVFRENVMNDWKKILGRNHIIKNLDDCDFTPIYEWHQSEKEKKKQMSAXXX 1584
            M DTDYMTKP F+EN  +DWKK+LG+NH ++NL+DCDF PIYEWHQ EKEK+KQM+    
Sbjct: 427  MLDTDYMTKPRFKENFFSDWKKMLGKNHTVQNLEDCDFGPIYEWHQQEKEKRKQMTTEEK 486

Query: 1583 XXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITI 1404
                        KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI P DITI
Sbjct: 487  KALKEERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDITI 546

Query: 1403 NIGKDAPIPECPIPGESWKEVRHDNTVTWLAYWLDPINGKEFKYVFLAASSSLKGQSDKE 1224
            NIGKDAPIPECPIPGE WKEVR+DNTVTWLA+W DPIN KE KYVFLAASS+LKGQSDKE
Sbjct: 547  NIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWNDPINQKECKYVFLAASSTLKGQSDKE 606

Query: 1223 KYEKARKLKGYIAGIRTAYTKDFAN-KDTAKRQIAVATYLIDKLALRAGNEKDDDEADTV 1047
            KYEKAR LK YI GIR AYTKDF N KD  K+QIAVATYLIDKLALRAGNEKDDDEADTV
Sbjct: 607  KYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTV 666

Query: 1046 GCCTLKVENVEPSPPNILKLDFLGKDSIRYQNEVEVEIPVFKAIQQFRSGKEGSDNLFDK 867
            GCCTLKVENVEP PPNILK+DF+GKDSIRYQNEV+VE  VFKAIQQFRSGKEG  +LFD+
Sbjct: 667  GCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGCADLFDR 726

Query: 866  LDTTKLNAHLKELMPGLSAKVFRTYNASITLDDMLNKETKGGDVSQKVAVYQHANKEVAI 687
            LDT+KLNAHLKELMPGL+AKVFRTYNASITLDDML+KETKGG V++KV VYQHANKEVAI
Sbjct: 727  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHANKEVAI 786

Query: 686  ICNHQRTVSKSHSTQMLRXXXXXXXXXXXXXXXXXXLSRAKKGKPPLKGSDGKTKRNMNP 507
            ICNHQRTVSKSHS QM R                  LSRAKKGKPP KG+DG+ KRN+NP
Sbjct: 787  ICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPAKGADGEPKRNLNP 846

Query: 506  EALEKKIAQTNTKIEKMERDKEIKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMF 327
            E+LE+KIAQTN KIEKMERDK+ KEDLK VAL TSKI+YLDPRITVAWCKR+EVPIEK+F
Sbjct: 847  ESLERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRHEVPIEKIF 906

Query: 326  NKSLLAKFAWAMDVEPSFRF 267
            NKSLLAKFAW+MDV+PSFRF
Sbjct: 907  NKSLLAKFAWSMDVDPSFRF 926


>XP_010266803.1 PREDICTED: DNA topoisomerase 1 alpha-like [Nelumbo nucifera]
          Length = 890

 Score = 1020 bits (2637), Expect = 0.0
 Identities = 555/902 (61%), Positives = 631/902 (69%), Gaps = 12/902 (1%)
 Frame = -2

Query: 2936 EDDRPLVFKRSTPLVKHNQVKPDVKKTSMQKPDGKSGRQMSDVRSPNGNGNGQDSNIQKG 2757
            +D+ P++FKR+    K NQ+  ++KK S +K DG SG+ +SD  SPNG    Q+S++QKG
Sbjct: 18   DDEGPIIFKRNNASSKKNQLNKELKKVSSRKRDGSSGKCVSDSFSPNG----QNSSLQKG 73

Query: 2756 KTGPSTKGXXXXXXXXXXXXXXXXXXXXXXXXPLASTKASTSGADRSRQNIQQNKTAT-- 2583
            K   S+K                            S+KASTS  D+ + + Q+N +    
Sbjct: 74   KAVQSSKASTGKSTE-------------------TSSKASTSITDKLKCSPQKNSSIDNM 114

Query: 2582 -VKVDKPSGXXXXXXXXXXXXXXXPLNSRLPVGGS--KGSISVVNKRPGSSGPASLAKPD 2412
              ++ KP                  L+ RLP   S  K   S V+K   S   +S     
Sbjct: 115  EKQLKKPCNEPYTDSVDSDDDKP--LSIRLPTSASLLKCKSSPVSKGLSSPVASSSQSEK 172

Query: 2411 PGV----KEEDSEDDIPLSHKFKQKSNAGESSNA--NDSDVKPFASKHQQNGTSARDNVK 2250
              V      EDSED++PLS K K K + G S     +  + KP  SK QQNG+S RDN  
Sbjct: 173  TNVTNKKSSEDSEDELPLSLKLKLKPSVGLSGKKFYDSGEEKPLVSKLQQNGSSKRDNEP 232

Query: 2249 NPSP-GLNKRPSAEVKCSGQSPVKKAKHAAASTPVNGKKVSVKAEPKKEXXXXXXDYATI 2073
              SP  LNKRP +    SGQS VKK K +  S P   K+ S+K+EPK+E          I
Sbjct: 233  LKSPKNLNKRPLSGANSSGQSLVKKLKVSEVSVPTKVKQTSIKSEPKEEDEDDIP----I 288

Query: 2072 SQRLKKPVTPIXXXXXXXXXXXXXXXXXXXXXXXXXKITKSTQFSKSLNVPPGSGEGQKW 1893
            SQRLKK  +                           K  K++++SKS  +PP SGEGQKW
Sbjct: 289  SQRLKKSASSDDKSLSLKKTTKVVSSSFKKTTNKLKKAAKNSKYSKSTKMPPSSGEGQKW 348

Query: 1892 TTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAVMQDTDYMTKPVFRENVM 1713
            TTL HNGVIFPP YKPHGVKMLY GKPVDLTPEQEEVATM AVM+DTDY TK  F EN M
Sbjct: 349  TTLEHNGVIFPPLYKPHGVKMLYNGKPVDLTPEQEEVATMFAVMKDTDYATKSRFIENFM 408

Query: 1712 NDWKKILGRNHIIKNLDDCDFTPIYEWHQSEKEKKKQMSAXXXXXXXXXXXXXXXKYMWA 1533
            NDW+ ILG+NH+IK  + CDFTPIYEWHQ EKEKKKQMSA               KYMWA
Sbjct: 409  NDWRTILGKNHVIKKFELCDFTPIYEWHQREKEKKKQMSAEEKKALKEEKLKQEEKYMWA 468

Query: 1532 IVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITINIGKDAPIPECPIPGES 1353
            IVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITINIGK APIPECPIPGE 
Sbjct: 469  IVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITINIGKGAPIPECPIPGER 528

Query: 1352 WKEVRHDNTVTWLAYWLDPINGKEFKYVFLAASSSLKGQSDKEKYEKARKLKGYIAGIRT 1173
            WKEVRHDNTVTWLA+W DPIN KEFKYVFLAASSSLKGQSDKEKYEKAR LK YI  IR 
Sbjct: 529  WKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIKDIRA 588

Query: 1172 AYTKDFANKDTAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPSPPNIL 993
             YT+DF +KD  KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVE  PPN L
Sbjct: 589  NYTRDFVSKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVELVPPNKL 648

Query: 992  KLDFLGKDSIRYQNEVEVEIPVFKAIQQFRSGKEGSDNLFDKLDTTKLNAHLKELMPGLS 813
            + DFLGKDSIRY N VEVE+ V+KAI QF++GKE  ++LFD LDT+KLNAHLKELMPGL+
Sbjct: 649  QFDFLGKDSIRYFNTVEVELAVYKAIGQFKNGKEDGEDLFDSLDTSKLNAHLKELMPGLT 708

Query: 812  AKVFRTYNASITLDDMLNKETKGGDVSQKVAVYQHANKEVAIICNHQRTVSKSHSTQMLR 633
            AKVFRTYNASITLD+MLN+E+KGGDV++K+AVYQHANKEVAIICNHQR+VSKSHS QM R
Sbjct: 709  AKVFRTYNASITLDEMLNRESKGGDVAEKIAVYQHANKEVAIICNHQRSVSKSHSAQMHR 768

Query: 632  XXXXXXXXXXXXXXXXXXLSRAKKGKPPLKGSDGKTKRNMNPEALEKKIAQTNTKIEKME 453
                              L+RAKKGKPPLKG+DGK KRN+ PEALEKKIAQ N KIEKME
Sbjct: 769  LDDKIKELKDALDELKTDLARAKKGKPPLKGADGKPKRNLTPEALEKKIAQANAKIEKME 828

Query: 452  RDKEIKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMFNKSLLAKFAWAMDVEPSF 273
            RDK+IKEDLKTVALGTSKINYLDPRI+VAWCKR+EVPIEK+FNKSLLAKFAWAMDV+P F
Sbjct: 829  RDKQIKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDF 888

Query: 272  RF 267
            RF
Sbjct: 889  RF 890


>XP_012845487.1 PREDICTED: DNA topoisomerase 1-like [Erythranthe guttata]
          Length = 894

 Score = 1014 bits (2622), Expect = 0.0
 Identities = 554/917 (60%), Positives = 635/917 (69%), Gaps = 20/917 (2%)
 Frame = -2

Query: 2957 MENGSDSEDDRPLVFKRSTPLVKHNQVKPDVKKTSMQKPDGKSGRQMSDVRSPNGNGNGQ 2778
            M    D +DD PLVFKRS    K  Q +P+  K S QK + + GRQ SDVR  NG     
Sbjct: 11   MMEDMDDDDDAPLVFKRSGSSSKPKQSEPE-NKLSSQKHNAQVGRQSSDVRPQNGT---- 65

Query: 2777 DSNIQKGK--TGPSTKGXXXXXXXXXXXXXXXXXXXXXXXXPLASTKASTSGADRSRQ-- 2610
            ++N QKGK  T  S+                          P  ++K STS    S+   
Sbjct: 66   NANAQKGKSVTSSSSMKPPVRPSLVSPKSSNSSVKASPIKSPDVNSKPSTSVVGESKSVK 125

Query: 2609 -NIQQNKTATVKVDKPSGXXXXXXXXXXXXXXXPLNSRLPVGGSKGSISVVNKRPGSSGP 2433
              I++  +   + DKP                  L++R   G SK + +  NK       
Sbjct: 126  STIKEENSEDSEDDKP------------------LSARQVAGSSKNNPNQTNK----PNA 163

Query: 2432 ASLAKPDPGVKEEDSEDDIPLSHKFKQKSNAGESSN--ANDSDVKPF-ASKHQQNGTSAR 2262
             +L K     K EDS+D+IPLS KF+ KSNAG S++  ++  + KP  A K  +NG+++ 
Sbjct: 164  PNLGKKSNVPKPEDSDDEIPLSAKFQGKSNAGASTSRSSHSEEKKPLVARKPDKNGSAST 223

Query: 2261 DNVKNPSPGLNKRPSAEVKCSGQSPVKKAKHAAASTPVNGKKVSVKAEPKKEXXXXXXDY 2082
            +  + PS  L KRP+  V  +GQS +KK K  + S     KK SVK E K E        
Sbjct: 224  E--RKPSTVLQKRPADGVASAGQSNLKKPK-LSDSLASKDKKASVKPEVKAEDDEDL--- 277

Query: 2081 ATISQRLKKPVTP------------IXXXXXXXXXXXXXXXXXXXXXXXXXKITKSTQFS 1938
              +SQR KK  TP                                      +++K   +S
Sbjct: 278  VPLSQRTKKSTTPEKKPSPALKVTKSTASISKKTNNKTNSKTNSKTNKKSKQVSKDNNYS 337

Query: 1937 KSLNVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAVMQ 1758
            KS  +PP SG+GQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPV+LTPEQEEVATM AVM 
Sbjct: 338  KSSKLPPSSGDGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVNLTPEQEEVATMYAVML 397

Query: 1757 DTDYMTKPVFRENVMNDWKKILGRNHIIKNLDDCDFTPIYEWHQSEKEKKKQMSAXXXXX 1578
            +TDY+ KP F+EN M DWKKILG+NH+I++L+ CDFTPIYEWHQ EKEKKKQMS      
Sbjct: 398  ETDYLKKPQFKENFMTDWKKILGKNHVIQSLEHCDFTPIYEWHQREKEKKKQMSTDEKKA 457

Query: 1577 XXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITINI 1398
                      KYMWA++DGV+EKVGNFRVEPPGLFRGRGEHPKMGKLK+RI PSDITINI
Sbjct: 458  LKEEKLKLEEKYMWAVLDGVREKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINI 517

Query: 1397 GKDAPIPECPIPGESWKEVRHDNTVTWLAYWLDPINGKEFKYVFLAASSSLKGQSDKEKY 1218
            G+DAPIPECPI GE WKE+RHDNTVTWLAYW DPINGKEFKYVFLAASS+LKGQSDKEKY
Sbjct: 518  GRDAPIPECPIEGERWKEIRHDNTVTWLAYWSDPINGKEFKYVFLAASSTLKGQSDKEKY 577

Query: 1217 EKARKLKGYIAGIRTAYTKDFANKDTAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCC 1038
            EKAR LK YI GIRTAYT+DF +KD AK+QIAVATYLIDKLALRAGNEKDDDEADTVGCC
Sbjct: 578  EKARLLKDYIQGIRTAYTRDFVSKDPAKKQIAVATYLIDKLALRAGNEKDDDEADTVGCC 637

Query: 1037 TLKVENVEPSPPNILKLDFLGKDSIRYQNEVEVEIPVFKAIQQFRSGKEGSDNLFDKLDT 858
            TLKVENVEP PPNILK DFLGKDSIRYQNEVEVE  VFKAIQQFRSGK+G D+LFDKLDT
Sbjct: 638  TLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDKLDT 697

Query: 857  TKLNAHLKELMPGLSAKVFRTYNASITLDDMLNKETKGGDVSQKVAVYQHANKEVAIICN 678
            +KLNAHLKELMPGL+AKVFRTYNASITLDD L++ETKGGD+++KV  Y HANKEVAIICN
Sbjct: 698  SKLNAHLKELMPGLTAKVFRTYNASITLDDKLSRETKGGDLAEKVVTYNHANKEVAIICN 757

Query: 677  HQRTVSKSHSTQMLRXXXXXXXXXXXXXXXXXXLSRAKKGKPPLKGSDGKTKRNMNPEAL 498
            HQRTVSK+HS QMLR                  L RA+KGKP L G+DGK KRN+NPEAL
Sbjct: 758  HQRTVSKTHSAQMLRLDEKIDELKGVLEELKTDLGRARKGKPLLAGADGKAKRNINPEAL 817

Query: 497  EKKIAQTNTKIEKMERDKEIKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMFNKS 318
            E+KIAQT  KIEKMERDKE KEDLKTVALGTSKINYLDPRITVAWCKR+EVPIEKMFNKS
Sbjct: 818  ERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKMFNKS 877

Query: 317  LLAKFAWAMDVEPSFRF 267
            LL KF+WAMDV+PSFRF
Sbjct: 878  LLEKFSWAMDVDPSFRF 894


>BAK32961.1 topoisomerase I [Ophiorrhiza ridleyana]
          Length = 926

 Score = 1013 bits (2619), Expect = 0.0
 Identities = 559/920 (60%), Positives = 635/920 (69%), Gaps = 28/920 (3%)
 Frame = -2

Query: 2942 DSEDDR-PLVFKRSTPLVKHNQVKPDVKKTSMQKPDGKSGRQMSDVRSPNGNGNGQDSNI 2766
            D EDD  P++FKRS P  K NQ   + KK S+QK  G+S    SDVR      NG+ S+ 
Sbjct: 14   DMEDDEGPVIFKRSNPTSKQNQANAEKKKLSLQKHVGQSAVHTSDVRP----ANGESSSA 69

Query: 2765 QKGKTGPSTKGXXXXXXXXXXXXXXXXXXXXXXXXPLASTKASTSGADRSRQNIQQNKTA 2586
            QKG+  PS +                         P A++K S S    ++Q      +A
Sbjct: 70   QKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAKQQNHHKSSA 129

Query: 2585 TVKVDKPS-GXXXXXXXXXXXXXXXPLNSRLPVGGSKGSISVVNKRPGSSGPASLAKPDP 2409
                 KPS                 PL +R     S G  +  NK  G S   S+ +P  
Sbjct: 130  AFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSMGKSNHANKEGGDS--CSIRRPVI 187

Query: 2408 GVKEEDSEDDIPLSHKFKQKSNAGES-SNANDSDVK-PFASKHQQNGTSARDNVKNPSPG 2235
              + EDSED+ PLS +F  KS+ GES S + DSD K P A+K QQNG+++ +   N S  
Sbjct: 188  E-ESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASPEGPMNKSAS 246

Query: 2234 L-NKRPSAEVKCSGQSPVKKAKHAAASTPVNGKKVSVKAEPKKEXXXXXXD--------- 2085
            L NKR   EVK   QS +KK K ++  T ++ K+ +VK EPK E                
Sbjct: 247  LSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQ 306

Query: 2084 ------------YATISQRLKK-PVTPIXXXXXXXXXXXXXXXXXXXXXXXXXKITKSTQ 1944
                        +A ISQR+KK PV+                           K+ + T 
Sbjct: 307  TAASKPKDEDDDHAPISQRIKKSPVSVSKSSAPVKKASTVVSTSLKKVNKKSKKVIRKTA 366

Query: 1943 FSKSLNVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAV 1764
            ++KS  VPPGSGEGQKWTTLVHNGV+FPPPYKPHGVKMLYK +P+ LTPEQEEVATM AV
Sbjct: 367  YTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQEEVATMFAV 426

Query: 1763 MQDTDYMTKPVFRENVMNDWKKILGRNHIIKNLDDCDFTPIYEWHQSEKEKKKQMSAXXX 1584
            M DTDYM KP F+EN  +DWKKILG+NH I+NL+DCDF PIYEWHQ EKEKKKQM+    
Sbjct: 427  MLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEK 486

Query: 1583 XXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITI 1404
                        KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI P DITI
Sbjct: 487  KALKEERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIRPRDITI 546

Query: 1403 NIGKDAPIPECPIPGESWKEVRHDNTVTWLAYWLDPINGKEFKYVFLAASSSLKGQSDKE 1224
            NIGKDAPIPECPIPGE WKEVR+DNTVTWLAYW DP+N KE KYVFLAASS+LKGQS KE
Sbjct: 547  NIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNIKECKYVFLAASSTLKGQSVKE 606

Query: 1223 KYEKARKLKGYIAGIRTAYTKDFAN-KDTAKRQIAVATYLIDKLALRAGNEKDDDEADTV 1047
            KYEKAR LK YI GIR AYTK F N KD  K+QIAVATYLIDKLALRAGNEKDDDEADTV
Sbjct: 607  KYEKARVLKDYIHGIRAAYTKGFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTV 666

Query: 1046 GCCTLKVENVEPSPPNILKLDFLGKDSIRYQNEVEVEIPVFKAIQQFRSGKEGSDNLFDK 867
            GCCTLKVENVEP PPNILK+DF+GKDSIRYQNEV+VE  VFKAIQQFRSGKEGS++LFD+
Sbjct: 667  GCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDR 726

Query: 866  LDTTKLNAHLKELMPGLSAKVFRTYNASITLDDMLNKETKGGDVSQKVAVYQHANKEVAI 687
            LDT+KLNAHLKELMPGL+AKVFRTYNASITLDDML+KETKGG +++KVAVYQHANKEVAI
Sbjct: 727  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKIAEKVAVYQHANKEVAI 786

Query: 686  ICNHQRTVSKSHSTQMLRXXXXXXXXXXXXXXXXXXLSRAKKGKPPLKGSDGKTKRNMNP 507
            ICNHQRTVSKSHS QM R                  LSRAKKGKPP K +DG+ KRN+NP
Sbjct: 787  ICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKDADGEPKRNLNP 846

Query: 506  EALEKKIAQTNTKIEKMERDKEIKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMF 327
            E+LE+KIAQTN KIEKMERDK+ KEDLK VAL TSKI+YLDPRITVAWCKR EVPIEKMF
Sbjct: 847  ESLERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEVPIEKMF 906

Query: 326  NKSLLAKFAWAMDVEPSFRF 267
            NKSLLAKFAWAMDV+PSFRF
Sbjct: 907  NKSLLAKFAWAMDVDPSFRF 926


>BAK32963.1 topoisomerase I [Ophiorrhiza sp. 35]
          Length = 920

 Score = 1011 bits (2613), Expect = 0.0
 Identities = 557/913 (61%), Positives = 629/913 (68%), Gaps = 28/913 (3%)
 Frame = -2

Query: 2942 DSEDDR-PLVFKRSTPLVKHNQVKPDVKKTSMQKPDGKSGRQMSDVRSPNGNGNGQDSNI 2766
            D EDD  P++FKRS P  K NQ   + KK S+QK  G+S    SDVR      NG+ S+ 
Sbjct: 14   DMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVRP----ANGESSSA 69

Query: 2765 QKGKTGPSTKGXXXXXXXXXXXXXXXXXXXXXXXXPLASTKASTSGADRSRQNIQQNKTA 2586
            QKG+  PS +                         P A++K S S    ++Q      +A
Sbjct: 70   QKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAKQQNHHKSSA 129

Query: 2585 TVKVDKPS-GXXXXXXXXXXXXXXXPLNSRLPVGGSKGSISVVNKRPGSSGPASLAKPDP 2409
                 KPS                 PL +R     SKG  +  NK  G S   S+ +P  
Sbjct: 130  AFIEPKPSVPPAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDS--CSIRRPVV 187

Query: 2408 GVKEEDSEDDIPLSHKFKQKSNAGES-SNANDSDVK-PFASKHQQNGTSARDNVKNPSPG 2235
              + EDSED+ PLS +F  KS+ GES S + DSD K P A+K QQNG+++RD   N S  
Sbjct: 188  E-ESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGPMNKSAS 246

Query: 2234 L-NKRPSAEVKCSGQSPVKKAKHAAASTPVNGKKVSVKAEPKKEXXXXXXDY-------- 2082
            L NKR   EVK   QS +KK K ++  T ++ K+ +VK EPK E                
Sbjct: 247  LSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQ 306

Query: 2081 -------------ATISQRLKK-PVTPIXXXXXXXXXXXXXXXXXXXXXXXXXKITKSTQ 1944
                         A ISQR+KK P +                           K+ K T 
Sbjct: 307  TAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTA 366

Query: 1943 FSKSLNVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAV 1764
            ++KS  VPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYK +P+ LTPEQEEVATM AV
Sbjct: 367  YTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPLTLTPEQEEVATMFAV 426

Query: 1763 MQDTDYMTKPVFRENVMNDWKKILGRNHIIKNLDDCDFTPIYEWHQSEKEKKKQMSAXXX 1584
            M DTDYM KP F+EN  +DWKK+LG+NH I+NL+DCDF PIYEWHQ E+EKKKQM+    
Sbjct: 427  MLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEREKKKQMTTEEK 486

Query: 1583 XXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITI 1404
                        KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRIHP DITI
Sbjct: 487  KALKDERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIHPRDITI 546

Query: 1403 NIGKDAPIPECPIPGESWKEVRHDNTVTWLAYWLDPINGKEFKYVFLAASSSLKGQSDKE 1224
            NIGKDAPIPECPIPGE WKEVR+DNTVTWLAYW DP+N KE KYVFLA SS+LKGQSDKE
Sbjct: 547  NIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPSSTLKGQSDKE 606

Query: 1223 KYEKARKLKGYIAGIRTAYTKDFAN-KDTAKRQIAVATYLIDKLALRAGNEKDDDEADTV 1047
            KYEKAR LK YI GIR AYTKDF N KD  K+QIAVATYLIDKLALRAGNEKDDDEADTV
Sbjct: 607  KYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTV 666

Query: 1046 GCCTLKVENVEPSPPNILKLDFLGKDSIRYQNEVEVEIPVFKAIQQFRSGKEGSDNLFDK 867
            GCCTL+VENVEP PPNILK+DF+GKDSIRYQNEV+VE  VFKAIQQFRSGKEGS++LFD+
Sbjct: 667  GCCTLRVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDR 726

Query: 866  LDTTKLNAHLKELMPGLSAKVFRTYNASITLDDMLNKETKGGDVSQKVAVYQHANKEVAI 687
            LDT+KLNAHLKELMPGL+AKVFRTYNASITLDDML+KETKGG V++KV VYQHANKEVAI
Sbjct: 727  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHANKEVAI 786

Query: 686  ICNHQRTVSKSHSTQMLRXXXXXXXXXXXXXXXXXXLSRAKKGKPPLKGSDGKTKRNMNP 507
            ICNHQRTVSKSHS QM R                  LSRAKKGKPP KG DG+ KRN+NP
Sbjct: 787  ICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGEPKRNLNP 846

Query: 506  EALEKKIAQTNTKIEKMERDKEIKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMF 327
            EALE+KIAQTN KIEKMERDK+ KEDLK VAL TSKI+YLDPRITVAWCKR EVPIEKMF
Sbjct: 847  EALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEVPIEKMF 906

Query: 326  NKSLLAKFAWAMD 288
            NKSLLAKFAWAM+
Sbjct: 907  NKSLLAKFAWAMN 919


>KZV21640.1 DNA topoisomerase 1-like [Dorcoceras hygrometricum]
          Length = 870

 Score = 1008 bits (2606), Expect = 0.0
 Identities = 550/896 (61%), Positives = 627/896 (69%), Gaps = 4/896 (0%)
 Frame = -2

Query: 2942 DSEDDRPLVFKRSTPLVKHNQVKPDVKKTSMQKPDGKSGRQMSDVRSPNGNGNGQDSNIQ 2763
            D +DD+PLVFKRS+   KHN                K+G+Q         + NG+ S++Q
Sbjct: 16   DDDDDQPLVFKRSSSSSKHNL---------------KNGQQ---------SRNGESSSVQ 51

Query: 2762 KGK-TGPSTKGXXXXXXXXXXXXXXXXXXXXXXXXPLASTKASTSGADRSRQNIQQNKTA 2586
            KG    PS+K                           A++K   S  D+     QQ    
Sbjct: 52   KGTLVPPSSKAPPIKSPLTSPKSSSSAAKESPVKSSAANSKRPMSETDKPNSVKQQ---- 107

Query: 2585 TVKVDKP-SGXXXXXXXXXXXXXXXPLNSRLPVGGSKGSISVVNKRPGSSGPASLAKPDP 2409
             VK ++P +                PL++RL    SKG+ +   +RP +    +L + + 
Sbjct: 108  -VKEEQPFAQAADETHDLEDSGDDTPLSARLLASSSKGNSNHAKQRPNA---LALVQKNS 163

Query: 2408 GVKEEDSEDDIPLSHKFKQKSNAGES-SNANDSDV-KPFASKHQQNGTSARDNVKNPSPG 2235
              K+EDS+D++PLS KF+ KS+   S S +N+SD  KP  +K  QNG+S+ D+ +     
Sbjct: 164  IPKKEDSDDEMPLSSKFQVKSDVRVSTSRSNNSDERKPILNKADQNGSSSTDHSQKKPSI 223

Query: 2234 LNKRPSAEVKCSGQSPVKKAKHAAASTPVNGKKVSVKAEPKKEXXXXXXDYATISQRLKK 2055
              KRP   VK   +SP KK K + AS+ +       +A+PK E       +  ISQR+K 
Sbjct: 224  AMKRPPNPVKVECRSPEKKPKLSNASSAIP------RAKPKAEDDDD---HVPISQRMKN 274

Query: 2054 PVTPIXXXXXXXXXXXXXXXXXXXXXXXXXKITKSTQFSKSLNVPPGSGEGQKWTTLVHN 1875
              +                           KI K+T++S S  V P SGEGQKWTTLVHN
Sbjct: 275  QSSSEKKSLSVKKVTKSVSAVATKTNKISKKIVKNTKYSISSKVLPNSGEGQKWTTLVHN 334

Query: 1874 GVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAVMQDTDYMTKPVFRENVMNDWKKI 1695
            GVIFPPPYKPHGVKMLYKGKPV LTPEQEEVATM AVM DTDYM KP F+EN M DW+KI
Sbjct: 335  GVIFPPPYKPHGVKMLYKGKPVVLTPEQEEVATMFAVMLDTDYMNKPKFKENFMTDWRKI 394

Query: 1694 LGRNHIIKNLDDCDFTPIYEWHQSEKEKKKQMSAXXXXXXXXXXXXXXXKYMWAIVDGVK 1515
            LG+NH I+ L+DCDFTPIYEWHQ EKEKKKQMS                KYMWAI+DGVK
Sbjct: 395  LGKNHTIQKLEDCDFTPIYEWHQKEKEKKKQMSTEEKKALKEEKLKQEEKYMWAILDGVK 454

Query: 1514 EKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITINIGKDAPIPECPIPGESWKEVRH 1335
            EKVGNFRVEPPGLFRGRGEHPKMGKLKKRI PSDI INIGKDA IPECPIPGESWKE+RH
Sbjct: 455  EKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDIIINIGKDAAIPECPIPGESWKEIRH 514

Query: 1334 DNTVTWLAYWLDPINGKEFKYVFLAASSSLKGQSDKEKYEKARKLKGYIAGIRTAYTKDF 1155
            DNTVTWLAYW DPIN KEFKYVFLAASS+LKGQSDKEKYEKAR LK YI GIR AYTKDF
Sbjct: 515  DNTVTWLAYWNDPINQKEFKYVFLAASSTLKGQSDKEKYEKARLLKNYIQGIRAAYTKDF 574

Query: 1154 ANKDTAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPSPPNILKLDFLG 975
            ++KD  ++QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP PPNILK DFLG
Sbjct: 575  SSKDPTRKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLG 634

Query: 974  KDSIRYQNEVEVEIPVFKAIQQFRSGKEGSDNLFDKLDTTKLNAHLKELMPGLSAKVFRT 795
            KDSIRYQNEV VE  VFKAIQQFR+GK+G D+LFDKLDT+KLNAHLKELMPGL+AKVFRT
Sbjct: 635  KDSIRYQNEVVVETAVFKAIQQFRNGKKGGDDLFDKLDTSKLNAHLKELMPGLTAKVFRT 694

Query: 794  YNASITLDDMLNKETKGGDVSQKVAVYQHANKEVAIICNHQRTVSKSHSTQMLRXXXXXX 615
            YNASITLDDMLN+ETKGG+V++K+ VYQHANKEVAIICNHQRTVSKSHS QMLR      
Sbjct: 695  YNASITLDDMLNRETKGGEVAEKIVVYQHANKEVAIICNHQRTVSKSHSAQMLRLDEKID 754

Query: 614  XXXXXXXXXXXXLSRAKKGKPPLKGSDGKTKRNMNPEALEKKIAQTNTKIEKMERDKEIK 435
                        LSRAKKGKPPLK +DGK KRNMNPEALEKKIAQT  KIEKMERDKE K
Sbjct: 755  ELKGAMEELREDLSRAKKGKPPLKSADGKPKRNMNPEALEKKIAQTAAKIEKMERDKETK 814

Query: 434  EDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMFNKSLLAKFAWAMDVEPSFRF 267
            EDLKT+ALGTS+INYLDPRITVAWCKR EVPIEK+FNKSLLAKFAWAMDV+P FRF
Sbjct: 815  EDLKTIALGTSRINYLDPRITVAWCKRQEVPIEKIFNKSLLAKFAWAMDVDPEFRF 870


>XP_016684952.1 PREDICTED: DNA topoisomerase 1-like [Gossypium hirsutum]
            XP_016684953.1 PREDICTED: DNA topoisomerase 1-like
            [Gossypium hirsutum] XP_016684954.1 PREDICTED: DNA
            topoisomerase 1-like [Gossypium hirsutum] XP_016684955.1
            PREDICTED: DNA topoisomerase 1-like [Gossypium hirsutum]
            XP_016684956.1 PREDICTED: DNA topoisomerase 1-like
            [Gossypium hirsutum] XP_016684957.1 PREDICTED: DNA
            topoisomerase 1-like [Gossypium hirsutum] XP_016684958.1
            PREDICTED: DNA topoisomerase 1-like [Gossypium hirsutum]
            XP_016684959.1 PREDICTED: DNA topoisomerase 1-like
            [Gossypium hirsutum]
          Length = 901

 Score = 1003 bits (2594), Expect = 0.0
 Identities = 545/901 (60%), Positives = 631/901 (70%), Gaps = 9/901 (0%)
 Frame = -2

Query: 2942 DSEDDRPLVFKRS-TPLVKHNQVKPDVKKTSMQKPDGKSGRQMSDVRSPNGNGNGQDSNI 2766
            D +DD P+VFKRS T   K NQ+  +VKK S Q+ DG+SGRQ S ++SPNG    Q+S  
Sbjct: 15   DEDDDGPVVFKRSNTSSSKQNQLNSEVKKASSQRSDGQSGRQASSLQSPNG----QNSVA 70

Query: 2765 QKGKTGPSTKGXXXXXXXXXXXXXXXXXXXXXXXXPLASTKASTSGADRSRQNIQQNKTA 2586
            +  K+   +K                         P+ S+KASTS +D+S+Q ++QNK  
Sbjct: 71   RTNKSILPSKSPPTRSPILSPKSSNSSAKASPVRSPVVSSKASTSLSDQSKQALKQNKFT 130

Query: 2585 TVKVDKPS-GXXXXXXXXXXXXXXXPLNSRLPVGGSKGSISVVNKRPGSSGPASLAKPDP 2409
             VK +K                   PL++RL     KG  S  NK   +S PA   +  P
Sbjct: 131  AVKEEKSLIKCTDETNSDDDDDDSKPLSARL-----KGISSQGNKGVSTSTPAQSQRLVP 185

Query: 2408 GVK----EEDSEDDIPLSHKFKQKSNAGESSNA--NDSDVKPFASKHQQNGTSARDNVKN 2247
             ++     ED +DD PLS +F  KSN G SS+      + KP  SK QQNG+  +D  + 
Sbjct: 186  KIEVKGSAEDPDDDAPLSARFSMKSNTGTSSSKPYGSHEKKPLPSKIQQNGSIMKDKQQK 245

Query: 2246 PSPGLNKRPSAEVKCSGQSPVKKAKHAAASTPVNGKKVSVKAEPKKEXXXXXXDYATISQ 2067
             S   +KRP  +   S QS  KK K +   T +  K+V+VKAE   E       +  ISQ
Sbjct: 246  CSVLSDKRPLDKGNSSDQSYAKKPKISDTPTTMKTKQVTVKAEKDDEDD-----HIPISQ 300

Query: 2066 RLKKPVTPIXXXXXXXXXXXXXXXXXXXXXXXXXKITKSTQFSKSLNVPPGSGEGQK-WT 1890
            R+KK V+ +                         K  K +++SKS  + P SG+GQK W+
Sbjct: 301  RIKKSVSSVSKTSSVKQKATKVVSSSFKKINKSKKDMKKSKYSKSTKLSPSSGDGQKKWS 360

Query: 1889 TLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAVMQDTDYMTKPVFRENVMN 1710
            TLVHNGVIFPPPYKPHGVKMLY G+PVDLTPEQEEVATM AVMQ+TDYM+KP F++N   
Sbjct: 361  TLVHNGVIFPPPYKPHGVKMLYDGQPVDLTPEQEEVATMFAVMQETDYMSKPQFKKNFWE 420

Query: 1709 DWKKILGRNHIIKNLDDCDFTPIYEWHQSEKEKKKQMSAXXXXXXXXXXXXXXXKYMWAI 1530
            DW K+LGRNH+IK+LD CDFTPIYEWH  EKEKKKQMS+               KYMWAI
Sbjct: 421  DWSKLLGRNHVIKSLDKCDFTPIYEWHLQEKEKKKQMSSEEKKALKEEKLKQEEKYMWAI 480

Query: 1529 VDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITINIGKDAPIPECPIPGESW 1350
            VDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RI P DITINIGKDAPIPECPIPGE W
Sbjct: 481  VDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPCDITINIGKDAPIPECPIPGERW 540

Query: 1349 KEVRHDNTVTWLAYWLDPINGKEFKYVFLAASSSLKGQSDKEKYEKARKLKGYIAGIRTA 1170
            K+++HDNTVTWLA+W DPIN KEFKYVFLAASSSLKGQSDKEKYEKAR LK YI  IR A
Sbjct: 541  KDIKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIKNIRAA 600

Query: 1169 YTKDFANKDTAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPSPPNILK 990
            YTKDF  KD  KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NVE  PPN LK
Sbjct: 601  YTKDFTAKDVTKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGNVECIPPNKLK 660

Query: 989  LDFLGKDSIRYQNEVEVEIPVFKAIQQFRSGKEGSDNLFDKLDTTKLNAHLKELMPGLSA 810
             DFLGKDSI+Y N VEVE+PV+KAI QF++ K  SD+LFD+LDT+KLNAHLKELMPGL+A
Sbjct: 661  FDFLGKDSIQYVNTVEVELPVYKAIGQFQTRKSKSDDLFDELDTSKLNAHLKELMPGLTA 720

Query: 809  KVFRTYNASITLDDMLNKETKGGDVSQKVAVYQHANKEVAIICNHQRTVSKSHSTQMLRX 630
            KVFRTYNASITLDDMLN+ET+ GDV++KV +YQ ANKEVAIICNHQR++SKSHS QM R 
Sbjct: 721  KVFRTYNASITLDDMLNQETEDGDVAEKVVIYQRANKEVAIICNHQRSISKSHSAQMSRL 780

Query: 629  XXXXXXXXXXXXXXXXXLSRAKKGKPPLKGSDGKTKRNMNPEALEKKIAQTNTKIEKMER 450
                             L RAKKGKPPLK +DGK KRN+ PEA+EKKIAQTN KIEKMER
Sbjct: 781  TEKITELKGVLKELKTDLDRAKKGKPPLKDADGKQKRNLTPEAIEKKIAQTNVKIEKMER 840

Query: 449  DKEIKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMFNKSLLAKFAWAMDVEPSFR 270
            D + KEDLKTVALGTSKINYLDPRITVAWCKR+EVPIEK+FNKSLLAKFAWAMDV+P FR
Sbjct: 841  DMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFR 900

Query: 269  F 267
            F
Sbjct: 901  F 901


>BAK32957.1 topoisomerase I [Ophiorrhiza harrisiana]
          Length = 920

 Score = 1003 bits (2593), Expect = 0.0
 Identities = 555/913 (60%), Positives = 628/913 (68%), Gaps = 28/913 (3%)
 Frame = -2

Query: 2942 DSEDDR-PLVFKRSTPLVKHNQVKPDVKKTSMQKPDGKSGRQMSDVRSPNGNGNGQDSNI 2766
            D EDD  P++FKRS P  K NQ   + KK S+QK  G+S    SDVR      NG+ S+ 
Sbjct: 14   DMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVRP----ANGESSSA 69

Query: 2765 QKGKTGPSTKGXXXXXXXXXXXXXXXXXXXXXXXXPLASTKASTSGADRSRQNIQQNKTA 2586
            QKG+  PS +                         P A++K S S    ++Q      +A
Sbjct: 70   QKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAKQQNHHKSSA 129

Query: 2585 TVKVDKPS-GXXXXXXXXXXXXXXXPLNSRLPVGGSKGSISVVNKRPGSSGPASLAKPDP 2409
                 KPS                 PL +R     SKG  +  NK  G S   S+ +P  
Sbjct: 130  AFIEPKPSVPPAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDS--CSIRRPVV 187

Query: 2408 GVKEEDSEDDIPLSHKFKQKSNAGES-SNANDSDVK-PFASKHQQNGTSARDNVKNPSPG 2235
              + EDSED+ PLS +F  KS+ GES S + DSD K P A+K QQNG+++RD   N S  
Sbjct: 188  E-ESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGPMNKSAS 246

Query: 2234 L-NKRPSAEVKCSGQSPVKKAKHAAASTPVNGKKVSVKAEPKKEXXXXXXDY-------- 2082
            L NKR   EVK   QS +KK K ++  T ++ K+ +VK EPK E                
Sbjct: 247  LSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQ 306

Query: 2081 -------------ATISQRLKK-PVTPIXXXXXXXXXXXXXXXXXXXXXXXXXKITKSTQ 1944
                         A ISQR+KK P +                           K+ K T 
Sbjct: 307  TAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTA 366

Query: 1943 FSKSLNVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMIAV 1764
            ++KS  VPPGSGEGQKWTTLVHNGV+F PPYKPHGVKMLYK +P+ LTPEQEEVATM AV
Sbjct: 367  YTKSSKVPPGSGEGQKWTTLVHNGVMFLPPYKPHGVKMLYKQQPLTLTPEQEEVATMFAV 426

Query: 1763 MQDTDYMTKPVFRENVMNDWKKILGRNHIIKNLDDCDFTPIYEWHQSEKEKKKQMSAXXX 1584
            M DTDYMTKP F+EN  +DWKK+LG+NH ++NL+DCDF PIYEWHQ EKEK+KQM+    
Sbjct: 427  MLDTDYMTKPRFKENFFSDWKKMLGKNHTVQNLEDCDFGPIYEWHQQEKEKRKQMTTEEK 486

Query: 1583 XXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITI 1404
                        KYM AIVDGVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRIHP DITI
Sbjct: 487  KALKEERLQQEEKYMRAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIHPRDITI 546

Query: 1403 NIGKDAPIPECPIPGESWKEVRHDNTVTWLAYWLDPINGKEFKYVFLAASSSLKGQSDKE 1224
            NIGKDAPIPECPIPGE WKEVR+DNTVTWLAYW DP+N KE KYVFLA SS+LKGQSDKE
Sbjct: 547  NIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPSSTLKGQSDKE 606

Query: 1223 KYEKARKLKGYIAGIRTAYTKDFAN-KDTAKRQIAVATYLIDKLALRAGNEKDDDEADTV 1047
            KYEKAR LK YI GIR AYTKDF N KD  K+QIAVATYLIDKLALRAGNEKDDDEADTV
Sbjct: 607  KYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTV 666

Query: 1046 GCCTLKVENVEPSPPNILKLDFLGKDSIRYQNEVEVEIPVFKAIQQFRSGKEGSDNLFDK 867
            GCCTLKVENVEP PPNILK+DF+GKDSIRYQNEV+VE  VFKAIQQFRSGKEGS++LFD+
Sbjct: 667  GCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDR 726

Query: 866  LDTTKLNAHLKELMPGLSAKVFRTYNASITLDDMLNKETKGGDVSQKVAVYQHANKEVAI 687
            LDT+KLNAHLKELMPGL+AKVFRTYNASITLDDML+KETKGG V++KV VYQHANKEVAI
Sbjct: 727  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHANKEVAI 786

Query: 686  ICNHQRTVSKSHSTQMLRXXXXXXXXXXXXXXXXXXLSRAKKGKPPLKGSDGKTKRNMNP 507
            ICNHQRTVSKSHS QM R                  LSRAKKGKPP KG DG+ KRN+NP
Sbjct: 787  ICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGEPKRNLNP 846

Query: 506  EALEKKIAQTNTKIEKMERDKEIKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMF 327
            EALE+KIAQTN KIEKMERDK+ KEDLK VAL TSKI+YLDPRITVAWCKR EVPIEKMF
Sbjct: 847  EALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEVPIEKMF 906

Query: 326  NKSLLAKFAWAMD 288
            NKSLLAKFAWAM+
Sbjct: 907  NKSLLAKFAWAMN 919