BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Angelica22_contig00010111
         (3833 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002280960.2| PREDICTED: DNA topoisomerase 1-like [Vitis v...  1309   0.0  
ref|XP_003545557.1| PREDICTED: DNA topoisomerase 1-like [Glycine...  1195   0.0  
ref|XP_003551158.1| PREDICTED: DNA topoisomerase 1-like [Glycine...  1194   0.0  
ref|XP_002528003.1| prokaryotic DNA topoisomerase, putative [Ric...  1180   0.0  
ref|NP_194849.3| DNA topoisomerase, type IA, core [Arabidopsis t...  1142   0.0  

>ref|XP_002280960.2| PREDICTED: DNA topoisomerase 1-like [Vitis vinifera]
          Length = 1185

 Score = 1309 bits (3387), Expect = 0.0
 Identities = 713/1187 (60%), Positives = 837/1187 (70%), Gaps = 37/1187 (3%)
 Frame = +1

Query: 181  LQNRALQY--CTGLHFRHSSFGGRCDSFVDLNFTKNRVSCVSFSDYPKAIRLE------- 333
            LQ R  Q    T L     + G +  +F  +NF K  +  +  +  PK +RL        
Sbjct: 33   LQYRGFQNYPATSLPCTRLNGGDKFGNFSQINFRKIGIPALVNNIQPKILRLNVNRNFHI 92

Query: 334  -------SRLSRVDEPQLGTGVL-ALARSVGVLGNGMLPSSGPYRGALSKRLFCHVT--- 480
                   SR +   + QL  G   A+    G L  G+  SS PY  AL+KR F  V    
Sbjct: 93   FGSLTDSSRFAVPVQSQLRLGFPNAVTPIYGTLDIGIRFSS-PYYKALAKRPFSQVPRVK 151

Query: 481  GKDGNFGSKDDKRGVKNSSFNVFNKHKK----------------RAKG-NQITGYSPSNS 609
             K  N G +D       S F  FNKH+K                RA G NQ T  S S+S
Sbjct: 152  NKGDNLGIRDGT-AENTSLFKPFNKHRKWEKSLTAHRRSFNGAVRAAGSNQPTKVSSSSS 210

Query: 610  RIAASEDADVVTSSNHIVEEVSKDVNVSTSKSKPKQQSGSRRRQKKSXXXXXXXXXXXEV 789
            R +A  D D++T    +V+   KD ++S S S     + +R  +              + 
Sbjct: 211  RRSALGDGDMMTQQEQLVDNGRKDADLSPSISTSPVSNNNRGSKATEKQRKQSRTKKNKE 270

Query: 790  QPXXXXXXXXXXXXXXAQSDQVPLESESAVVQPXXXXXXXXXXXXXXXQSDQIPLEPEKS 969
            Q                       ++ S V Q                +  Q P   + +
Sbjct: 271  QV-------------------TSTDASSDVAQKKSTKSSSEANKSNITKKSQSPQASKNN 311

Query: 970  LTDAMTEELLDSSVPXXXXXXXXXXXXXXXXXXVVPSARAEAPSVSSAIDLPQKQTSQTS 1149
             T     E LDSSV                      S+  +  S   A + P+KQT  T 
Sbjct: 312  STGNKPVEALDSSVSTKSQSKK-----------ATGSSNKKGKSPKVANESPKKQTVHTM 360

Query: 1150 VKPKPHKQRVIKQLYPPTGKSVLVVESVTKAKVIQGYLGDMFEVIPSYGHVRDLAARSGS 1329
             K K  +QR +K+LYP +GKSV+VVESVTKAKVIQGYLGDM+EV+PSYGHVRDLA RSGS
Sbjct: 361  GKIKSLEQRPLKKLYPSSGKSVVVVESVTKAKVIQGYLGDMYEVLPSYGHVRDLAGRSGS 420

Query: 1330 VRPDEDFSMVWEVPSAAWTHLKSIKVALSGAKNLILASDPDREGEAIAWHIVEMLEQQDA 1509
            VRPD+DFSMVWEVPSAAWTHLKSIKVAL GA+NLILASDPDREGEAIAWHI+EML QQDA
Sbjct: 421  VRPDDDFSMVWEVPSAAWTHLKSIKVALGGAENLILASDPDREGEAIAWHIIEMLLQQDA 480

Query: 1510 LHDDINLARVVFNEITEASIKTALLAPRDIDANLVNSYLARRALDYLIGFNISPVLWRKL 1689
            LH D+ +ARVVF+EITE+SIK+AL APR+ID NLV++YLARRALDYLIGFNISP+LWRKL
Sbjct: 481  LHKDLTVARVVFHEITESSIKSALDAPREIDVNLVHAYLARRALDYLIGFNISPLLWRKL 540

Query: 1690 PGCRSAGRVQSAALSLICDREMEIDGFKPQEYWTLDVLFREXXXXXXXXXXXXXXYLTHF 1869
            PGC+SAGRVQSAAL+LICDREMEID FKPQEYWT++V F                YLTHF
Sbjct: 541  PGCQSAGRVQSAALALICDREMEIDEFKPQEYWTVEVEFNRKQGSSMNSKFFPS-YLTHF 599

Query: 1870 QSKKLSKLSINSQTKAIDIQAEIEASEFEVSNSKRSKMRKNPPAPYITSSLQQDAANKLS 2049
             SKKL++ SI+S T+A  I+ EI + EF+V  SKR+KMRKNPP PYITS+LQQDAANKL 
Sbjct: 600  DSKKLNQFSISSHTEAKAIEQEINSLEFKVIGSKRNKMRKNPPTPYITSTLQQDAANKLH 659

Query: 2050 FPATYTMKLAQKLYEGVQLPDGVSAGLITYIRTDGLHISDEACKDICSLVRERYGESFAS 2229
            F A YTMKLAQ+LYEGVQL DG +AGLITY+RTDGLH+SDEA KDI SLV ERYG + AS
Sbjct: 660  FSAMYTMKLAQRLYEGVQLSDGKAAGLITYMRTDGLHVSDEAAKDIRSLVAERYGSNLAS 719

Query: 2230 DGARKYFKKVKNAQEAHEAIRPTNIRRVPSSLAGVLDEDSLKLYTLIWSRTLACQMEPAI 2409
            DG RKYFKKVKNAQEAHEAIRPT+I+R+PS LAGVLDEDSLKLYTLIWSRT+ACQMEPA 
Sbjct: 720  DGVRKYFKKVKNAQEAHEAIRPTDIQRLPSMLAGVLDEDSLKLYTLIWSRTMACQMEPAT 779

Query: 2410 YDQIQVDIGNADRSIIFRSSCSRTEFLGYQAAFEDVETRAIRNRDNEVNDRSDVSDVLSN 2589
             DQIQVDIGNA+ S++FRS+CS  EF GYQA ++DVE +AIR  +NE N+R +V   LS+
Sbjct: 780  IDQIQVDIGNANESVVFRSTCSGVEFFGYQAVYKDVEAKAIRVDENEGNERGEVFKALSS 839

Query: 2590 LKAGDPLYLGKVEPKQHHTQPPPRFSEGSLVKMLEELGIGRPSTYASTMKVLQDRNYITV 2769
            LKAGDPLYL  +E +QHHT PP R+SEG+LVK LEELGIGRPSTYA TMKVLQDRNY+TV
Sbjct: 840  LKAGDPLYLSLLELEQHHTLPPSRYSEGALVKKLEELGIGRPSTYAITMKVLQDRNYVTV 899

Query: 2770 KSRILYPEFRGRMLSAFLSNHFSEVTDYSFTADMETELDNVSAGLTEWKGLLGDYWTRFS 2949
            K+R+LYPEFRGRM+SAFLS+HFSEVTDYSFTADMETELDNVSAGLTEWKGLL DYWTRFS
Sbjct: 900  KNRVLYPEFRGRMVSAFLSHHFSEVTDYSFTADMETELDNVSAGLTEWKGLLKDYWTRFS 959

Query: 2950 KYCESTSNVHIHEVEKMLEKTFGDFVFSSLPNKSRTCPSCREGTLVFKVSRFGVGYFIGC 3129
             YC   SNVHIH+VEKMLEK FGDF+FS LP+KSRTCPSC EGTL+FKVSRFG GYFIGC
Sbjct: 960  MYCNRVSNVHIHQVEKMLEKKFGDFLFSFLPDKSRTCPSCMEGTLIFKVSRFGSGYFIGC 1019

Query: 3130 DQHPRCKYIAKTIHGDDDDDEGTPENHNLEEPKVLGVKPGSDEKILLKNGPYGYYVQLGV 3309
            DQHP+CKYIAK + G DDD+E   ++   EEPK LG+ PGS EKILLKNGPYG+Y+QLG 
Sbjct: 1020 DQHPKCKYIAKMLDG-DDDEEVASQDKTFEEPKALGLSPGSSEKILLKNGPYGFYLQLGE 1078

Query: 3310 DRKGYLPKRASVSQVKDTSSITLEDALEMLRYPVTLGEHPEDGHPVILKLGRFGFSIKHR 3489
            DRKGYLPKRASVS +KD  SITLEDALE+LRYPVTLG HP D HPV+LKL + GFSI+HR
Sbjct: 1079 DRKGYLPKRASVSHIKDVGSITLEDALELLRYPVTLGNHPNDDHPVVLKLAKNGFSIRHR 1138

Query: 3490 RTVSPVPKNMKPDAISLEKALQILLSKDAKRSGRPKNKPKYEEIDAI 3630
            RT++PVPKN+KP+ I+LEKAL++LL KD K+SGRPKNK K E  +A+
Sbjct: 1139 RTIAPVPKNIKPNDITLEKALKLLLGKDVKQSGRPKNKKKQEVYEAM 1185


>ref|XP_003545557.1| PREDICTED: DNA topoisomerase 1-like [Glycine max]
          Length = 1197

 Score = 1195 bits (3092), Expect = 0.0
 Identities = 589/855 (68%), Positives = 707/855 (82%), Gaps = 3/855 (0%)
 Frame = +1

Query: 1078 SARAEAPSVS-SAIDLPQKQTSQTSV--KPKPHKQRVIKQLYPPTGKSVLVVESVTKAKV 1248
            SA  E P  S SA D  +K+   +SV  + KP      K LYPPT KSV+VVESVTKAKV
Sbjct: 342  SAIEEMPENSASAKDELKKKNGNSSVIEEVKPPWNFTYKPLYPPTRKSVVVVESVTKAKV 401

Query: 1249 IQGYLGDMFEVIPSYGHVRDLAARSGSVRPDEDFSMVWEVPSAAWTHLKSIKVALSGAKN 1428
            I+ YLGDM+EV+PSYGHVRDLAARSGSVRPD+DFSMVWEVP  AWTHLKSIKVALS A+N
Sbjct: 402  IKRYLGDMYEVLPSYGHVRDLAARSGSVRPDDDFSMVWEVPPPAWTHLKSIKVALSRAEN 461

Query: 1429 LILASDPDREGEAIAWHIVEMLEQQDALHDDINLARVVFNEITEASIKTALLAPRDIDAN 1608
            LILASDPDREGEAIAWHI+EML+QQ ALHD+I+LARVVF+EITE SIK AL  PR+ID N
Sbjct: 462  LILASDPDREGEAIAWHIIEMLQQQGALHDNISLARVVFHEITEKSIKGALQTPREIDVN 521

Query: 1609 LVNSYLARRALDYLIGFNISPVLWRKLPGCRSAGRVQSAALSLICDREMEIDGFKPQEYW 1788
            LV +YLARRALDYLIGFNISP+LWRKLPGC+SAGRVQSAALSLICDREMEID FKP+EYW
Sbjct: 522  LVQAYLARRALDYLIGFNISPLLWRKLPGCQSAGRVQSAALSLICDREMEIDEFKPKEYW 581

Query: 1789 TLDVLFREXXXXXXXXXXXXXXYLTHFQSKKLSKLSINSQTKAIDIQAEIEASEFEVSNS 1968
            T++V  ++              +LTHF SKKL+K SI S T+A DI++ I +++F V + 
Sbjct: 582  TVEVQMKKKELRSNKNLTFPA-HLTHFDSKKLNKFSITSDTEARDIRSNINSADFHVVSL 640

Query: 1969 KRSKMRKNPPAPYITSSLQQDAANKLSFPATYTMKLAQKLYEGVQLPDGVSAGLITYIRT 2148
            K++K R+NPP PYITS+LQQDAANKL F A++TMKLAQKLYEGV+L D V+ GLITYIRT
Sbjct: 641  KKNKSRRNPPTPYITSTLQQDAANKLHFTASHTMKLAQKLYEGVELSDSVAVGLITYIRT 700

Query: 2149 DGLHISDEACKDICSLVRERYGESFASDGARKYFKKVKNAQEAHEAIRPTNIRRVPSSLA 2328
            DGLHISDEA   I SL+ ERYG+ F S  A KY+KKVKNAQEAHEAIRPT+IR++PS L+
Sbjct: 701  DGLHISDEAVASIRSLIIERYGQDFVSQSAPKYYKKVKNAQEAHEAIRPTDIRKLPSMLS 760

Query: 2329 GVLDEDSLKLYTLIWSRTLACQMEPAIYDQIQVDIGNADRSIIFRSSCSRTEFLGYQAAF 2508
             +LDE+SLKLYTLIWSRT++CQMEPA+++QIQ+DIGN D SII +SS SR EF GY+A F
Sbjct: 761  AILDEESLKLYTLIWSRTVSCQMEPAVFEQIQLDIGNLDESIILQSSISRVEFPGYRAVF 820

Query: 2509 EDVETRAIRNRDNEVNDRSDVSDVLSNLKAGDPLYLGKVEPKQHHTQPPPRFSEGSLVKM 2688
             D+ + A++++ ++ +       VL++LK GD L++ + EP QHHTQPPPR+SE SLVK 
Sbjct: 821  TDIVSEAVQDKGSDESSHDQTFGVLNSLKTGDSLHVVQTEPNQHHTQPPPRYSEASLVKK 880

Query: 2689 LEELGIGRPSTYASTMKVLQDRNYITVKSRILYPEFRGRMLSAFLSNHFSEVTDYSFTAD 2868
            LEELGIGRPSTYAST+KVLQDRNY+TVKSR+L PEFRGRM+SAFLSNHFSEVTDYSFTAD
Sbjct: 881  LEELGIGRPSTYASTIKVLQDRNYVTVKSRVLSPEFRGRMVSAFLSNHFSEVTDYSFTAD 940

Query: 2869 METELDNVSAGLTEWKGLLGDYWTRFSKYCESTSNVHIHEVEKMLEKTFGDFVFSSLPNK 3048
            METELDNVSAGLTEWKGLL DYWTRF  YCE TSNVHIH+VEKMLEK FGD++F+SLP++
Sbjct: 941  METELDNVSAGLTEWKGLLRDYWTRFKSYCERTSNVHIHQVEKMLEKKFGDYLFASLPDQ 1000

Query: 3049 SRTCPSCREGTLVFKVSRFGVGYFIGCDQHPRCKYIAKTIHGDDDDDEGTPENHNLEEPK 3228
            SR CPSC EGTL+FKVSRFG GYFIGCDQHPRCKYIAKT++G +++++ +  N  +EEPK
Sbjct: 1001 SRVCPSCMEGTLIFKVSRFGAGYFIGCDQHPRCKYIAKTLYGTEEEEDASQPNTRIEEPK 1060

Query: 3229 VLGVKPGSDEKILLKNGPYGYYVQLGVDRKGYLPKRASVSQVKDTSSITLEDALEMLRYP 3408
            +LGV  GS+EK+LLK+GPYG YVQLG DRKGY+P+RASVS +KD  SITL+DALE+L+YP
Sbjct: 1061 LLGVTSGSNEKVLLKSGPYGVYVQLGEDRKGYIPRRASVSHIKDVDSITLKDALEVLQYP 1120

Query: 3409 VTLGEHPEDGHPVILKLGRFGFSIKHRRTVSPVPKNMKPDAISLEKALQILLSKDAKRSG 3588
            +TLG HP+DG PVIL+L R GF ++HRRT++ +PKN+KP  ++LEKAL+ L   D +RSG
Sbjct: 1121 LTLGNHPKDGQPVILRLARAGFCVRHRRTIASIPKNVKPSDVTLEKALEYLSGDDVRRSG 1180

Query: 3589 RPKNKPKYEEIDAIE 3633
            RPK      E++ IE
Sbjct: 1181 RPKKGKSKVEVEVIE 1195


>ref|XP_003551158.1| PREDICTED: DNA topoisomerase 1-like [Glycine max]
          Length = 1070

 Score = 1194 bits (3090), Expect = 0.0
 Identities = 585/845 (69%), Positives = 703/845 (83%), Gaps = 2/845 (0%)
 Frame = +1

Query: 1105 SSAIDLPQKQTSQTSV--KPKPHKQRVIKQLYPPTGKSVLVVESVTKAKVIQGYLGDMFE 1278
            +SA D  +K+   +S+  + KP      K LYPPTGKSV+VVESVTKAKVI+ YLGDM+E
Sbjct: 225  ASAKDKVKKKNGNSSLIEEAKPLWNFTYKPLYPPTGKSVVVVESVTKAKVIKRYLGDMYE 284

Query: 1279 VIPSYGHVRDLAARSGSVRPDEDFSMVWEVPSAAWTHLKSIKVALSGAKNLILASDPDRE 1458
            V+PSYGHVRDLAARSGSVRPD+DFSMVWEVPS AWTHLKSIKVALSGA+NLILASDPDRE
Sbjct: 285  VLPSYGHVRDLAARSGSVRPDDDFSMVWEVPSPAWTHLKSIKVALSGAENLILASDPDRE 344

Query: 1459 GEAIAWHIVEMLEQQDALHDDINLARVVFNEITEASIKTALLAPRDIDANLVNSYLARRA 1638
            GEAIAWHI+EML+QQ ALHD+I+LARVVF+EITE SIK +L  PR+ID NLV +YLARRA
Sbjct: 345  GEAIAWHIIEMLQQQGALHDNISLARVVFHEITEKSIKGSLQTPREIDINLVQAYLARRA 404

Query: 1639 LDYLIGFNISPVLWRKLPGCRSAGRVQSAALSLICDREMEIDGFKPQEYWTLDVLFREXX 1818
            LDYLIGF+ISP+LWRKLPGC+SAGRVQSAALSLICDREMEID FKP+EYW ++V  ++  
Sbjct: 405  LDYLIGFSISPLLWRKLPGCQSAGRVQSAALSLICDREMEIDEFKPKEYWIVEVQLKKKE 464

Query: 1819 XXXXXXXXXXXXYLTHFQSKKLSKLSINSQTKAIDIQAEIEASEFEVSNSKRSKMRKNPP 1998
                        +LTHF SKKL++ SI S T+A DIQ+ I +++F V + K+SK R+NPP
Sbjct: 465  LRSNKNLTFPA-HLTHFDSKKLNQFSITSDTEARDIQSTINSADFHVVSLKKSKSRRNPP 523

Query: 1999 APYITSSLQQDAANKLSFPATYTMKLAQKLYEGVQLPDGVSAGLITYIRTDGLHISDEAC 2178
             PYITS+LQQDAANKL F A++TMKLAQKLYEGV+L DG++ GLITYIRTDGLHISDE  
Sbjct: 524  TPYITSTLQQDAANKLHFTASHTMKLAQKLYEGVELSDGIAVGLITYIRTDGLHISDEVV 583

Query: 2179 KDICSLVRERYGESFASDGARKYFKKVKNAQEAHEAIRPTNIRRVPSSLAGVLDEDSLKL 2358
              I SL+ ERYG+ F S  A KY+KKVKNAQEAHEAIRPT+I ++PS L+G+LD +SLKL
Sbjct: 584  ASIRSLIIERYGQDFVSQSAPKYYKKVKNAQEAHEAIRPTDICKLPSMLSGILDGESLKL 643

Query: 2359 YTLIWSRTLACQMEPAIYDQIQVDIGNADRSIIFRSSCSRTEFLGYQAAFEDVETRAIRN 2538
            YTLIWSRT++CQM PA+++QIQ++IGN D+SII RSS SR EF GY+A F D+ T A+++
Sbjct: 644  YTLIWSRTVSCQMGPAVFEQIQLNIGNPDKSIILRSSSSRVEFPGYRAVFTDIVTEAVQD 703

Query: 2539 RDNEVNDRSDVSDVLSNLKAGDPLYLGKVEPKQHHTQPPPRFSEGSLVKMLEELGIGRPS 2718
            +D++   R     VL++LK GDPL++ + EP QHHTQPPPR+SE SLVK LEELGIGRPS
Sbjct: 704  KDSDEFSRDQTFGVLNSLKTGDPLHVVQTEPNQHHTQPPPRYSEASLVKKLEELGIGRPS 763

Query: 2719 TYASTMKVLQDRNYITVKSRILYPEFRGRMLSAFLSNHFSEVTDYSFTADMETELDNVSA 2898
            TYAST+KVLQDRNY+TVKSR+L PEFRG M+SAFLS+HFSEV DY FTADMETELDNVS 
Sbjct: 764  TYASTIKVLQDRNYVTVKSRVLSPEFRGCMVSAFLSHHFSEVMDYGFTADMETELDNVSG 823

Query: 2899 GLTEWKGLLGDYWTRFSKYCESTSNVHIHEVEKMLEKTFGDFVFSSLPNKSRTCPSCREG 3078
            GLTEWKGLL DYWTRF  YCE TSNVHIH+VEKMLEK FGD++F+SLP++SR CPSC EG
Sbjct: 824  GLTEWKGLLRDYWTRFKSYCERTSNVHIHQVEKMLEKKFGDYLFASLPDQSRVCPSCMEG 883

Query: 3079 TLVFKVSRFGVGYFIGCDQHPRCKYIAKTIHGDDDDDEGTPENHNLEEPKVLGVKPGSDE 3258
            TL+FKVSRFG GYFIGCDQHPRCKYIAKT++G +++++ +  N  +EEPK+LGV  GS E
Sbjct: 884  TLIFKVSRFGAGYFIGCDQHPRCKYIAKTLYGTEEEEDASQPNSRVEEPKLLGVTSGSYE 943

Query: 3259 KILLKNGPYGYYVQLGVDRKGYLPKRASVSQVKDTSSITLEDALEMLRYPVTLGEHPEDG 3438
            K+LLK+GPYG YVQLG DRKGY+PKRASVS +KD  SITL+DALE+L+YP+TLG HP+DG
Sbjct: 944  KVLLKSGPYGVYVQLGEDRKGYIPKRASVSHIKDVDSITLKDALEVLQYPLTLGNHPKDG 1003

Query: 3439 HPVILKLGRFGFSIKHRRTVSPVPKNMKPDAISLEKALQILLSKDAKRSGRPKNKPKYEE 3618
             PVILKL R G  ++HRRTV+ VPKN+KP  ++LEKAL+ L   D +RSGRPK K K +E
Sbjct: 1004 QPVILKLARAGLCVRHRRTVASVPKNVKPSDVTLEKALEYLSGDDVRRSGRPKGKSKVQE 1063

Query: 3619 IDAIE 3633
            ++ IE
Sbjct: 1064 VEVIE 1068


>ref|XP_002528003.1| prokaryotic DNA topoisomerase, putative [Ricinus communis]
            gi|223532629|gb|EEF34415.1| prokaryotic DNA
            topoisomerase, putative [Ricinus communis]
          Length = 1071

 Score = 1180 bits (3053), Expect = 0.0
 Identities = 588/834 (70%), Positives = 683/834 (81%), Gaps = 1/834 (0%)
 Frame = +1

Query: 1123 PQKQTSQTSV-KPKPHKQRVIKQLYPPTGKSVLVVESVTKAKVIQGYLGDMFEVIPSYGH 1299
            P KQ     + K KP +Q  +K LYPPT KSV+VVESVTKAKVIQGYLG MFEV+PSYGH
Sbjct: 260  PDKQQQHKPMHKSKPFRQGSLKPLYPPTAKSVVVVESVTKAKVIQGYLGPMFEVLPSYGH 319

Query: 1300 VRDLAARSGSVRPDEDFSMVWEVPSAAWTHLKSIKVALSGAKNLILASDPDREGEAIAWH 1479
            VRDLAARSGSVRPD+DFSMVWEVPS AWTHLK+IKVAL+GA+NL+LASDPDREGEAIAWH
Sbjct: 320  VRDLAARSGSVRPDDDFSMVWEVPSPAWTHLKTIKVALNGAENLVLASDPDREGEAIAWH 379

Query: 1480 IVEMLEQQDALHDDINLARVVFNEITEASIKTALLAPRDIDANLVNSYLARRALDYLIGF 1659
            I+EML+QQDALH  + +ARVVF+EITE SIK AL APR+ID NLV++YLARRALDYLIGF
Sbjct: 380  IIEMLQQQDALHQGVTVARVVFHEITEQSIKNALQAPREIDLNLVHAYLARRALDYLIGF 439

Query: 1660 NISPVLWRKLPGCRSAGRVQSAALSLICDREMEIDGFKPQEYWTLDVLFREXXXXXXXXX 1839
            NISP+LWRKLPGC+SAGRVQSAALSLICDREMEID F PQEYWT+DV             
Sbjct: 440  NISPLLWRKLPGCQSAGRVQSAALSLICDREMEIDEFTPQEYWTIDV-----ELYIMETG 494

Query: 1840 XXXXXYLTHFQSKKLSKLSINSQTKAIDIQAEIEASEFEVSNSKRSKMRKNPPAPYITSS 2019
                  LTHF   KL++LS+ S T+A DI+ +I  + F V+ +K SKMR+NPP PYITS+
Sbjct: 495  SSVNARLTHFDFNKLNQLSVRSHTEARDIEQKINVASFLVAGAKESKMRRNPPTPYITST 554

Query: 2020 LQQDAANKLSFPATYTMKLAQKLYEGVQLPDGVSAGLITYIRTDGLHISDEACKDICSLV 2199
            LQQDAANKL F + YTMKLAQKLYEGVQL DG + GLITYIRTDGLHIS EA K+I SLV
Sbjct: 555  LQQDAANKLHFSSMYTMKLAQKLYEGVQLSDGKTTGLITYIRTDGLHISGEAVKEIHSLV 614

Query: 2200 RERYGESFASDGARKYFKKVKNAQEAHEAIRPTNIRRVPSSLAGVLDEDSLKLYTLIWSR 2379
             ERYG+ FASD  RKYFKKVKNAQEAHEA+RPTN+R +PS LA VLDEDSLKLYTLIWSR
Sbjct: 615  IERYGQDFASDSPRKYFKKVKNAQEAHEAVRPTNVRMLPSMLANVLDEDSLKLYTLIWSR 674

Query: 2380 TLACQMEPAIYDQIQVDIGNADRSIIFRSSCSRTEFLGYQAAFEDVETRAIRNRDNEVND 2559
            T+ACQMEPA  +QIQVDIGNA+ SI  RS+CS   FLGYQ  +ED E  AI+N+++EVND
Sbjct: 675  TVACQMEPATIEQIQVDIGNANGSITLRSACSGVGFLGYQIVYEDKEAGAIKNKESEVND 734

Query: 2560 RSDVSDVLSNLKAGDPLYLGKVEPKQHHTQPPPRFSEGSLVKMLEELGIGRPSTYASTMK 2739
             ++   +L +LK GDP  L +V+ KQH TQPPPR+SEG+LVK LEELGIGRPSTYAST+K
Sbjct: 735  HNEAFGILKSLKPGDPFNLSEVKLKQHFTQPPPRYSEGTLVKKLEELGIGRPSTYASTLK 794

Query: 2740 VLQDRNYITVKSRILYPEFRGRMLSAFLSNHFSEVTDYSFTADMETELDNVSAGLTEWKG 2919
            VLQDRNY+TVK+R+L PEFRGRM+SAFLS HF+EVTDYSFTADMETELDNVSAGLTEWKG
Sbjct: 795  VLQDRNYVTVKNRVLNPEFRGRMVSAFLSQHFTEVTDYSFTADMETELDNVSAGLTEWKG 854

Query: 2920 LLGDYWTRFSKYCESTSNVHIHEVEKMLEKTFGDFVFSSLPNKSRTCPSCREGTLVFKVS 3099
            LL DYWTRFS YC    +VHIH+VEKMLEKTFGDF+F SLP+ SRTCPSC EGTL+FK  
Sbjct: 855  LLRDYWTRFSSYCSHAESVHIHQVEKMLEKTFGDFLFGSLPDDSRTCPSCLEGTLIFK-- 912

Query: 3100 RFGVGYFIGCDQHPRCKYIAKTIHGDDDDDEGTPENHNLEEPKVLGVKPGSDEKILLKNG 3279
                 Y +              I+GDD+D+E TP+N+++EEPK+LGV P S EK+LLKNG
Sbjct: 913  -----YML-------------DIYGDDEDEE-TPQNNSVEEPKLLGVHPVSTEKVLLKNG 953

Query: 3280 PYGYYVQLGVDRKGYLPKRASVSQVKDTSSITLEDALEMLRYPVTLGEHPEDGHPVILKL 3459
            PYG+Y+QLG DRKGY PKRASVS +KD  +ITLEDALE+LRYPVTLG HP+DGHP+ILKL
Sbjct: 954  PYGFYLQLGEDRKGYTPKRASVSHIKDVDNITLEDALELLRYPVTLGNHPKDGHPIILKL 1013

Query: 3460 GRFGFSIKHRRTVSPVPKNMKPDAISLEKALQILLSKDAKRSGRPKNKPKYEEI 3621
             + GF+++HRRT++ VPKNMKPD +SLEKAL++L   D +RSGRPK KPK EE+
Sbjct: 1014 AKVGFAVRHRRTIASVPKNMKPDNVSLEKALELLSGDDVRRSGRPKRKPKVEEV 1067


>ref|NP_194849.3| DNA topoisomerase, type IA, core [Arabidopsis thaliana]
            gi|332660478|gb|AEE85878.1| DNA topoisomerase, type IA,
            core [Arabidopsis thaliana]
          Length = 1284

 Score = 1142 bits (2954), Expect = 0.0
 Identities = 553/817 (67%), Positives = 676/817 (82%), Gaps = 1/817 (0%)
 Frame = +1

Query: 1171 QRVIKQLYPPTGKSVLVVESVTKAKVIQGYLGDMFEVIPSYGHVRDLAARSGSVRPDEDF 1350
            Q   K LYPP+GKSV+VVES+TKAK+IQGYLGDM+EV+PSYGH+RDLA RSGSVRPD+DF
Sbjct: 462  QNASKPLYPPSGKSVIVVESMTKAKIIQGYLGDMYEVLPSYGHIRDLATRSGSVRPDDDF 521

Query: 1351 SMVWEVPSAAWTHLKSIKVALSGAKNLILASDPDREGEAIAWHIVEMLEQQDALHDDINL 1530
            SMVWEVPS+AWTH+KSIKVAL+GA+NLILASDPDREGEAIAWHI+EML+QQ ALH+ + +
Sbjct: 522  SMVWEVPSSAWTHIKSIKVALNGAENLILASDPDREGEAIAWHIIEMLQQQGALHESMTV 581

Query: 1531 ARVVFNEITEASIKTALLAPRDIDANLVNSYLARRALDYLIGFNISPVLWRKLPGCRSAG 1710
            ARVVF+EITE++IK+AL +PR+ID +LV++YLARRALDYLIGFNISP+LWRKLPGC SAG
Sbjct: 582  ARVVFHEITESAIKSALQSPREIDGDLVHAYLARRALDYLIGFNISPLLWRKLPGCPSAG 641

Query: 1711 RVQSAALSLICDREMEIDGFKPQEYWTLDVLFREXXXXXXXXXXXXXXYLTHFQSKKLSK 1890
            RVQSAAL+L+CDRE EIDGFKPQEYWT+ +  +               +LT   SK+L++
Sbjct: 642  RVQSAALALVCDRESEIDGFKPQEYWTVGIKVK-----GKDNSATFSAHLTSLNSKRLNQ 696

Query: 1891 LSINSQTKAIDIQAEIEASEFEVSNSKRSKMRKNPPAPYITSSLQQDAANKLSFPATYTM 2070
            LSI+S+  A DI+  I++  F V  +K S  RKNPP PYITS+LQQDAANKL F   +TM
Sbjct: 697  LSISSEANAQDIEQRIKSEGFLVKGTKTSTTRKNPPTPYITSTLQQDAANKLHFSTAHTM 756

Query: 2071 KLAQKLYEGVQLPDGVSAGLITYIRTDGLHISDEACKDICSLVRERYGESFASDGARKYF 2250
            KLAQKLYEGVQL DG SAGLITY+RTDGLHI+DEA KDI SLV ERYG++F SD  RKYF
Sbjct: 757  KLAQKLYEGVQLSDGKSAGLITYMRTDGLHIADEAIKDIQSLVAERYGKNFTSDSPRKYF 816

Query: 2251 KKVKNAQEAHEAIRPTNIRRVPSSLAGVLDEDSLKLYTLIWSRTLACQMEPAIYDQIQVD 2430
            KKVKNAQEAHEAIRPT+IRR+PS++A +LD DSLKLYTLIWSR +ACQMEPA   QIQ+D
Sbjct: 817  KKVKNAQEAHEAIRPTDIRRLPSTIASLLDADSLKLYTLIWSRAVACQMEPASIAQIQLD 876

Query: 2431 IGNADRSIIFRSSCSRTEFLGYQAAFEDVETRAIRNRDNEVN-DRSDVSDVLSNLKAGDP 2607
            IGNA  SIIFRSSCS+ EFLGYQA +ED E +AI+N DN+ + +R +    LS+LK GD 
Sbjct: 877  IGNASESIIFRSSCSKVEFLGYQAVYEDPEAKAIKNNDNDQSSEREETFKTLSSLKDGDL 936

Query: 2608 LYLGKVEPKQHHTQPPPRFSEGSLVKMLEELGIGRPSTYASTMKVLQDRNYITVKSRILY 2787
            L +G+VE KQHHTQ PPR+SEGSLVK LEELGIGRPSTYAS  +VLQ R Y+T+K+R+LY
Sbjct: 937  LQIGEVELKQHHTQHPPRYSEGSLVKKLEELGIGRPSTYASIFRVLQHRKYVTIKNRVLY 996

Query: 2788 PEFRGRMLSAFLSNHFSEVTDYSFTADMETELDNVSAGLTEWKGLLGDYWTRFSKYCEST 2967
            PEFR RM+SAFL+++F+E+TDYSFTADMETELDNVS G+TEWKGLL DYWTRFS YC+  
Sbjct: 997  PEFRARMVSAFLTHYFTEITDYSFTADMETELDNVSGGVTEWKGLLRDYWTRFSAYCKRV 1056

Query: 2968 SNVHIHEVEKMLEKTFGDFVFSSLPNKSRTCPSCREGTLVFKVSRFGVGYFIGCDQHPRC 3147
             NV   +VEKMLEK + D +FS LP  SRTCPSC EGTL FK S+FG GYFIGCDQHP C
Sbjct: 1057 ENVQRSQVEKMLEKKYEDVLFSLLPYPSRTCPSCMEGTLSFKASKFGAGYFIGCDQHPSC 1116

Query: 3148 KYIAKTIHGDDDDDEGTPENHNLEEPKVLGVKPGSDEKILLKNGPYGYYVQLGVDRKGYL 3327
            K+IAKT++G+D+D++  P+N+ +EEPK+LG+ P + EK++LK GPYG+YVQLG D+KG+ 
Sbjct: 1117 KFIAKTLYGEDEDEDDPPKNNCVEEPKLLGLHPNTSEKVILKCGPYGHYVQLGEDKKGHT 1176

Query: 3328 PKRASVSQVKDTSSITLEDALEMLRYPVTLGEHPEDGHPVILKLGRFGFSIKHRRTVSPV 3507
            PKRA+ + +KD +SITLE ALE+LRYP+TLG HPEDG PV+LKL + GF+IKHRR ++ V
Sbjct: 1177 PKRANAAHIKDVNSITLESALELLRYPLTLGTHPEDGQPVVLKLSKSGFTIKHRRNMATV 1236

Query: 3508 PKNMKPDAISLEKALQILLSKDAKRSGRPKNKPKYEE 3618
            PKN +P  ++LE+A+++L  K+ ++SGRP      EE
Sbjct: 1237 PKNTEPGEVTLERAMKLLSGKNVRKSGRPPKSILPEE 1273